Genome ID:GCA_001075325.1 PPRS_table
 

Probiotic potential risk score

ARGs (CARD) VFs (VFDB) PGs (PHI-base) PPRS
22135310338.83

CARD

ARO accession ARO name Identity Coverage CARD name Accession no.
ARO:3003922oqxA100.00100.00oqxAEU370913.1
ARO:3004580Klebsiella pneumoniae KpnE100.00100.00Kpne_KpnEAP006725.1
ARO:3004583Klebsiella pneumoniae KpnF100.00100.00Kpne_KpnFAP006725.1
ARO:3005049CrcB100.00100.00CrcBHF536482.1
ARO:3005059LptD100.00100.00LptDCP007727.1
ARO:3003923oqxB99.81100.00oqxBEU370913.1
ARO:3004588Klebsiella pneumoniae KpnG99.74100.00Kpne_KpnGACWO01000051.1
ARO:3005044OmpA99.7295.19OmpAFO834906.1
ARO:3005047eptB99.4697.04eptBFO203501.1
ARO:3004111FosA699.28100.00FosA6KU254579.1
ARO:3005053ArnT99.27100.00ArnTFO834906.1
ARO:3000518CRP99.05100.00CRPAP009048.1
ARO:3003890Escherichia coli UhpT with mutation conferring resistance to fosfomycin95.03100.00Ecol_UhpT_FOFHG738867.1
ARO:3004597Klebsiella pneumoniae KpnH94.02100.00Kpne_KpnHASTU01000063.1
ARO:3003950msbA92.78100.00msbAU00096.3
ARO:3000263marA92.7497.64marAAP009048.1
ARO:3000516emrR92.57100.00emrRU00096.3
ARO:3000828baeR91.25100.00baeRAP009048.1
ARO:3001328Escherichia coli mdfA85.61100.00Ecol_mdfAJQ394987.1
ARO:3005069rsmA85.25100.00rsmAAF061757.1
ARO:3003378Escherichia coli AcrAB-TolC with MarR mutations conferring resistance to ciprofloxacin and tetracycline84.03100.00Ecol_MarR_MULTU00096.1
ARO:3003578PmrF83.69101.55PmrFU00096.1

Virulence Factor Database Search

Gene ID Gene name Identity Coverage e-value VF name VF category Accession no.
VFG049219dotU100.00100.000.0T6SS-IIIEffector delivery systemYP_005227576
VFG048245fimA100.00100.000.0Type I fimbriaeAdherenceWP_002916190
VFG048230fimB100.00100.000.0Type I fimbriaeAdherenceWP_042931240
VFG048287fimF100.00100.000.0Type I fimbriaeAdherenceWP_014906962
VFG003114fyuA/psn100.00100.000.0YersiniabactinNutritional/Metabolic factorWP_000784549
VFG048683hcp/tssD100.00100.000.0T6SSEffector delivery systemYP_005226602
VFG048549iroB100.00100.000.0SalNutritional/Metabolic factorWP_004890934
VFG048553iroD100.00100.000.0SalNutritional/Metabolic factorWP_014907291
VFG048327mrkH100.00100.000.0Type 3 fimbriaeBiofilmWP_004152886
VFG048348mrkJ100.00100.000.0Type 3 fimbriaeBiofilmWP_004149658
VFG049007rcsA100.00100.000.0RcsABRegulationWP_002911561
VFG003386ybtA100.00100.000.0YersiniabactinNutritional/Metabolic factorWP_000140406
VFG048585ybtU100.00100.000.0YbtNutritional/Metabolic factorWP_000982853
VFG048839wcaJ100.0097.750.0CapsuleImmune modulationWP_041937831
VFG048861KPN2242_RS1628099.92100.000.0CapsuleImmune modulationWP_004180513
VFG048872KPN2242_RS1628599.91100.000.0CapsuleImmune modulationWP_004180514
VFG048883KPN2242_RS1629099.91100.000.0CapsuleImmune modulationWP_004180515
VFG049313A79E_RS1021599.89100.000.0T6SS-IIIEffector delivery systemWP_002910453
VFG000366ybtQ99.89100.000.0YersiniabactinNutritional/Metabolic factorWP_002212761
VFG048263fimC99.86100.000.0Type I fimbriaeAdherenceYP_005228657
VFG048385mrkB99.8696.690.0Type 3 fimbriaeBiofilmYP_005228646
VFG048277fimD99.85100.000.0Type I fimbriaeAdherenceWP_009308599
VFG049018rcsB99.85100.000.0RcsABRegulationWP_002913007
VFG048395mrkA99.84100.000.0Type 3 fimbriaeBiofilmYP_005228647
VFG048355mrkF99.84100.000.0Type 3 fimbriaeBiofilmYP_005228643
VFG048332mrkI99.83100.000.0Type 3 fimbriaeBiofilmWP_002916079
VFG049134acrA99.8399.920.0AcrABAntimicrobial activity/Competitive advantage-
VFG048927KPN2242_RS1630599.82100.000.0CapsuleImmune modulationWP_004180522
VFG048787sciN/tssJ99.82100.000.0T6SSEffector delivery systemWP_004176417
VFG048894KPN2242_RS1629599.81100.000.0CapsuleImmune modulationWP_004180517
VFG049287sciN99.81100.000.0T6SS-IIIEffector delivery systemWP_004175532
VFG003381ybtE99.81100.000.0YersiniabactinNutritional/Metabolic factorWP_001088826
VFG048663dotU/tssL99.8176.960.0T6SSEffector delivery systemWP_004176431
VFG043624mrkD99.80100.000.0Type 3 fimbriaeBiofilmWP_004149659
VFG049209impJ99.78100.000.0T6SS-IIIEffector delivery systemYP_005227577
VFG048535iroE99.7899.360.0SalNutritional/Metabolic factorWP_004148380
VFG000363irp299.77100.000.0YersiniabactinNutritional/Metabolic factorWP_002212775
VFG048905KPN2242_RS1630099.77100.000.0CapsuleImmune modulationWP_004899437
VFG002747ybtP99.77100.000.0YersiniabactinNutritional/Metabolic factorWP_001327262
VFG048375mrkC99.76100.000.0Type 3 fimbriaeBiofilmYP_005228645
VFG048438entC99.75100.000.0EntNutritional/Metabolic factorWP_004176916
VFG000360ybtT99.75100.000.0YersiniabactinNutritional/Metabolic factorWP_002212799
VFG048744KPHS_2313099.74100.000.0T6SSEffector delivery systemYP_005226613
VFG049195clpV99.73100.000.0T6SS-IIEffector delivery systemWP_004150973
VFG049281impH99.70100.000.0T6SS-IIIEffector delivery systemWP_072157837
VFG048541iroN99.6886.260.0SalNutritional/Metabolic factorWP_041169040
VFG048307fimH99.67100.000.0Type I fimbriaeAdherenceWP_041937815
VFG048255fimI99.63100.000.0Type I fimbriaeAdherenceWP_004174507
VFG048776tssG99.63100.000.0T6SSEffector delivery systemYP_005226618
VFG048552iroC99.62100.000.0SalNutritional/Metabolic factor-
VFG012551irp199.59100.000.0Yersiniabactin siderophoreNutritional/Metabolic factor-
VFG048524entD99.5775.320.0EntNutritional/Metabolic factorYP_005225736
VFG049298impF99.55100.000.0T6SS-IIIEffector delivery systemWP_004175538
VFG049306impA99.51100.000.0T6SS-IIIEffector delivery systemYP_005227545
VFG048466fepD99.50100.000.0EntNutritional/Metabolic factorWP_004223587
VFG048507fes99.50100.000.0EntNutritional/Metabolic factorWP_019705362
VFG048615iutA99.50100.000.0AerobactinNutritional/Metabolic factorYP_005226287
VFG048794galF99.44100.000.0CapsuleImmune modulationWP_049256767
VFG048654vasE/tssK99.41100.000.0T6SSEffector delivery systemWP_004224345
VFG048850KPN2242_RS1627599.38100.000.0CapsuleImmune modulationWP_004899428
VFG048235fimE99.34100.000.0Type I fimbriaeAdherenceWP_002916189
VFG049269impG99.26100.000.0T6SS-IIIEffector delivery systemWP_004148784
VFG048487fepC99.25100.000.0EntNutritional/Metabolic factorWP_002893737
VFG048316fimK99.22100.000.0Type I fimbriaeAdherenceWP_015958940
VFG048409entA99.20100.000.0EntNutritional/Metabolic factorWP_086074289
VFG048630vipA/tssB99.19100.000.0T6SSEffector delivery systemWP_004224339
VFG048514fepA99.1786.140.0EntNutritional/Metabolic factorYP_005225737
VFG048606iucC99.14100.000.0AerobactinNutritional/Metabolic factorWP_004213922
VFG048428entE99.13100.000.0EntNutritional/Metabolic factorWP_012068426
VFG048770tssF99.09100.000.0T6SSEffector delivery systemWP_004892596
VFG048600iucA99.01100.000.0AerobactinNutritional/Metabolic factorWP_004213920
VFG048474fepG98.99100.000.0EntNutritional/Metabolic factorYP_005225742
VFG049082KPN2242_RS1619598.99100.000.0LPSImmune modulationWP_004899405
VFG048419entB98.94100.000.0EntNutritional/Metabolic factorWP_004210873
VFG048704vgrG/tssI98.90100.000.0T6SSEffector delivery systemYP_005226604
VFG048760impA/tssA98.87100.000.0T6SSEffector delivery systemWP_004183804
VFG048603iucB98.84100.000.0AerobactinNutritional/Metabolic factorWP_004213921
VFG049037cpsG98.8097.730.0LPSImmune modulationWP_020956641
VFG049058KPHS_3547098.74100.000.0LPSImmune modulationYP_005227847
VFG048996rmpA98.74100.000.0RmpARegulationWP_004213609
VFG048696clpV/tssH98.66100.640.0T6SSEffector delivery systemWP_040188146
VFG048949KPN2242_RS1631598.41100.000.0CapsuleImmune modulationWP_004184823
VFG048977KPK_RS0803598.31100.000.0CapsuleImmune modulationWP_012541091
VFG048610iucD98.28100.000.0AerobactinNutritional/Metabolic factorWP_004145304
VFG048970ugd98.20100.000.0CapsuleImmune modulationWP_004175261
VFG003509ybtS98.16100.000.0YersiniabactinNutritional/Metabolic factorWP_005168693
VFG049040KP1_RS1722598.0895.450.0LPSImmune modulationWP_074160401
VFG049102KPN2242_RS1620598.05100.000.0LPSImmune modulationWP_041937830
VFG048562ybtX97.97100.000.0YbtNutritional/Metabolic factorWP_014907272
VFG048754icmF/tssM97.9289.150.0T6SSEffector delivery systemWP_077250640
VFG048986KPR_RS0904597.71100.000.0CapsuleImmune modulationWP_004144150
VFG048712KPHS_2305097.69100.000.0T6SSEffector delivery systemYP_005226605
VFG040963gspG97.64100.000.0PulEffector delivery systemWP_002889054
VFG048938KPN2242_RS1631097.35100.000.0CapsuleImmune modulationWP_004899441
VFG049025KPHS_3544097.34100.000.0LPSImmune modulationYP_005227844
VFG006011STER_RS0532097.33100.000.0CapsuleImmune modulationWP_011681177
VFG048736tle197.3099.770.0T6SSEffector delivery systemYP_005226611
VFG006079STER_RS0708596.7498.330.0CapsuleImmune modulationWP_011681442
VFG040971KPK_RS2175596.63100.000.0PulEffector delivery systemWP_008807384
VFG006087STER_RS0710096.4999.520.0CapsuleImmune modulationWP_011681445
VFG006089rfbD94.95100.000.0CapsuleImmune modulationWP_011681446
VFG048828gndA94.88100.000.0CapsuleImmune modulationWP_004899420
VFG040961gspE94.7799.870.0PulEffector delivery systemWP_012542822
VFG005556tig/ropA94.70100.000.0Trigger factorStress survivalWP_011680653
VFG040962gspF94.57100.000.0PulEffector delivery systemWP_012542823
VFG040966gspJ94.47100.000.0PulEffector delivery systemWP_008807379
VFG006000STER_RS0531594.26100.000.0CapsuleImmune modulationWP_011681176
VFG005976STER_RS0530594.06100.000.0CapsuleImmune modulationWP_011681174
VFG040960gspD93.97100.000.0PulEffector delivery systemWP_162493344
VFG005359plr/gapA93.87100.100.0Streptococcal plasmin receptor/GAPDHAdherenceWP_002899102
VFG040964gspH93.8199.810.0PulEffector delivery systemWP_008807378
VFG040968gspL93.6871.260.0PulEffector delivery systemWP_012542825
VFG006022rfbB93.50100.000.0CapsuleImmune modulationWP_002947383
VFG040970KPK_RS2175091.1999.730.0PulEffector delivery systemWP_012542827
VFG040958gspB91.04100.000.0PulEffector delivery systemWP_012542819
VFG040969KPK_RS2174590.5599.790.0PulEffector delivery systemWP_012542826
VFG006041rfbA90.46100.000.0CapsuleImmune modulationWP_011681286
VFG034408yagZ/ecpA90.4199.320.0ECPAdherenceWP_000730972
VFG005579eno90.27100.000.0Streptococcal enolaseExoenzymeWP_000022815
VFG034492yagW/ecpD89.3997.870.0ECPAdherenceWP_001323478
VFG034447yagY/ecpB88.64100.000.0ECPAdherenceWP_000716398
VFG006047STU_RS1464088.4799.860.0CapsuleImmune modulationWP_011226047
VFG005325cbpD88.2399.880.0AutolysinExoenzymeWP_011680595
VFG040959gspC87.5699.880.0PulEffector delivery systemWP_008807374
VFG002415yagX/ecpC87.4699.920.0ECPAdherenceWP_001131063
VFG000477rpoS86.8199.800.0RpoSRegulationNP_461845
VFG034513yagV/ecpE85.0399.300.0ECPAdherenceWP_001339257
VFG001443ompA84.22101.920.0OmpAInvasionAAF37887
VFG005382srtA84.1699.740.0Sortase AExoenzymeWP_011681303
VFG034392ykgK/ecpR86.74100.002.48e-173ECPAdherenceWP_001323479
VFG049329KPR_RS1700099.39100.006.82e-172T6SS-IIIEffector delivery systemWP_004145442
VFG040965gspI96.17100.007.61e-172PulEffector delivery systemWP_004894160
VFG040957gspS92.80100.003.71e-155PulEffector delivery systemWP_012968915
VFG048740KPHS_23120100.00100.002.57e-135T6SSEffector delivery systemYP_005226612
VFG000478fur83.9896.477.97e-118FurRegulationNP_459678
VFG048498entF99.3260.660.0EntNutritional/Metabolic factorWP_012737619
VFG049244vgrG97.1263.240.0T6SS-IIIEffector delivery systemWP_004899018
VFG006075STER_RS0707594.4960.490.0CapsuleImmune modulationWP_011681440
VFG005189fbp5490.7363.590.0FBPsAdherenceWP_011227179

PHIB-BLAST

Protein ID Gene name Identity Coverage e-value Function Gene ID
W9BBU8leuC100.0099.790.03-Isopropylmalate dehydratase large subunitAIT01851
W9BHK2ybtS100.0099.770.0Isochorismate synthase/isochorismate-pyruvate lyaseAIT04278
A0A086IQC3proV100.0099.750.0Glycine betaine/L-proline transport ATP-binding proteinAIS99989
W9BCN0leuB100.0099.730.03-Isopropylmalate dehydrogenaseAIT01852
O87753ompk35100.0099.720.0PorinADG27466
A6TF99arnC100.0099.700.0Putative sugar transferaseABR79233
A0A0W8AWM7yhbU100.0099.700.0Ubiquinone biosynthesis proteinARA47379
A6TF97arnD100.0099.670.0Hypothetical proteinABR79231
W1I1Q2lpxO100.0099.670.0Fe2+/alpha-ketoglutaratedependent dioxygenaseCDL64297
W9BEV6ycgE100.0099.590.0HTH-type transcriptional regulatorARA45326
A6TAW6gntR100.0099.580.0Fatty acid metabolism regulatorABR77737
W9BHK4irp299.8599.950.0YersiniabactinCDO15339
A6TF98arnA99.8599.850.0Hypothetical proteinABR79232
P46359psn99.8599.850.0Iron bindingCAA84487
U5U790oqxA99.7499.740.0RND family efflux transporterAIS72928
Q6U607iucA99.7399.860.0AerobactinAAR07714
W9B4Q6oqxB99.7199.900.0Multidrug efflux pumpCDO12913
A0A2X3EJX6fimD99.7188.090.0Type 1 fimbriae anchoring proteinSQC44282
A0A086VCI7ybtP99.6599.820.0ATP Binding Cassette ProteinAJE56481
W9BNM8entB99.6599.650.0Enterobactin and salmochelinANN51031
W9B3Z6yfiN99.5199.750.0c-di-GMP turnover enzymeCDO12934
A6TFA0arnB99.4799.740.0Putative aminotransferaseABR79234
A6TF96arnT99.4699.820.04-Amino-4-deoxy-L-arabinose transferaseABR79230
A0A076ZK37VK055_198099.4481.820.0HADa ATPase, P typeAIK80586
Q1RPI4ybtE99.4399.810.0YersiniabactinAIX63806
A0A076ZMY5VK055_195299.3899.800.0Betaine aldehyde dehydrogenaseAIK80558
B0LF88fimH99.3499.670.0Type 1 fimbriae adhesinABW24959
A0A0E0V727ybtQ99.3399.830.0ATP Binding Cassette ProteinAEQ13038
A0A164J6A6rarA99.3399.780.0Holliday junction DNA helicaseSAS94147
B5Y383pgaC99.3299.770.0Production of poly-b-linkedN-acetylglucosamineACI10823
B5Y1W2leuA99.2399.620.02-Isopropylmalate synthaseACI08908
Q6U5X7iroB99.1999.730.0SalmochelinAAR07744
A0A076ZHT9VK055_196199.1999.600.0Serine 3-dehydrogenaseAIK80567
B5XSN9phoQ98.9799.590.0govern the expression of cps and of the loci implicated in lipid A remodelingACI11151
A0A0F6AXS9lon98.8599.870.0ATP-dependent proteaseACY87051
Q7CPB9oxyR98.6999.670.0Regulatory protein sensor for oxidative stressAAL22963
P60651speB98.6999.670.0AgmatinaseAAC75974
P0AC41sdhA98.6499.830.0Succinate dehydrogenase avoprotein subunitAAA23895
P13445RpoS98.4899.700.0RNA polymerase sigma factorBAA02747
B0LF89fimK98.4499.780.0Pilus regulatory geneABW24960
Q8CL21ybtX98.1291.030.0Inner membrane protein, membrane permeaseAAS61888
A0A0F6B5R3STM14_RS1528598.0799.820.0Formate hydrogenlyase subunit 4ACY89857
P0A9E5FNR97.6099.600.0global regulatorAAA87981
A0A0D6I2I2spoT97.17100.000.0(P)ppGpp synthetaseAKH09371
P00722lacZ96.6899.900.0Beta-galactosidaseAAA24053
Q8ZLT3pnp96.4197.750.0polynucleotide phosphorylase, an exoribonuclease involved in RNA processing and degradationAAL22154
P0A2P8fruR95.8099.400.0Regulators of systemic infectionCRA_SALTY
P0A1P6glnA95.7499.790.0Glutamine synthetaseAAL22846
Q1JLQ2MntE95.5399.440.0Manganese HomeostasisABF32167
P0A7F6speD95.4599.620.0S-adenosylmethionine decarboxylase proenzymeAAC73231
D6QLX8OmpK3695.3899.460.0outer membrane proteinsADG56549
B5QZL1prt95.3299.670.0OAg biosynthesisCAR33649
P65882purA95.1499.770.0Pathogenicity islandAAL23186
P08982envZ94.9897.120.0Regulators of systemic infectionENVZ_SALTY
P75825hcp94.9199.820.0Hydroxylamine reductaseAAC73960
P13036fecA94.6486.580.0Ferric citrate outer membrane transporterBAE78282
A0A0F6B0W4sufB94.5599.800.0Sulfur mobilizationACY88142
D2TU77cpxA94.5399.780.0Two-component sensor kinaseCBG90543
Q8ZME2relA93.9799.870.0(P)ppGpp synthetase IAAL21836
D4HYB2guaB93.2499.800.0Inosine-5'-monophosphate dehydrogenaseCBA21987
Q97S31metE93.0699.870.0Methionine biosynthesis enzymesAAK74738
A0A0F6B941atpB92.9999.630.0F0F1 ATP synthase subunit AACY91043
P67331spr008492.8898.180.0pathogenitcity relatedAAK98888
C3T032ppk192.7399.710.0Polyphosphate kinase 1ACI80066
Q1J943prsA292.1998.460.0Ribose-phosphate pyrophosphokinaseABF36968
P63883amiC92.0999.760.0N-acetylmuramoyl-L-alanine amidaseAAC75856
P27550acs92.0399.850.0Acetyl-coenzyme A synthetaseAAC43163
P0A6Z3htpG91.6799.840.0heat shock protein 90 chaperoneAAA23460
P0A6T3galK91.6299.740.0GalactokinaseCAA26172
B5XY48OmpA291.29100.850.0outer membrane proteinsACI08342
P12681pgtP91.1499.780.0Phosphoglycerate transporter proteinAAL21299
D2TPE2tolB90.9399.770.0Colicin import proteinCBG87511
P32705actP90.9199.820.0Acetate/glycolate:cation symporterAAC77037
P05416glgA90.3499.580.0Glycogen synthaseAAL22395
P0A9G2nhaR90.1797.680.0Transcriptional activator proteinCAA27969
P36548amiA90.0099.660.0N-acetylmuramoyl-L-alanine amidaseAAC75488
Q99Z66ptsI89.9599.830.0Phosphoenolpyruvate-protein phosphotransferaseAAK34199
D4HXG4purF89.9099.800.0AmidophosphoribosyltransferaseCBA21663
P23865Prc89.8899.850.0Tail-specific proteaseBAA00577
E1AP33corA89.8799.680.0Magnesium/nickel/cobalt transporterHM852064
Q8DPC2potA89.8499.480.0ABC transporter ATP-binding protein - spermidine/putrescine transportAAL00050
A7ZRQ3sufI89.7999.790.0Cell division proteinABV16661
A0A380PIP1bipA89.7799.670.0Putative GTPaseCAL18716
Q8DYL6uvrB89.5999.850.0Excinuclease ABC, B subunitAE014259_2
D2TI55map89.3999.620.0Effector proteinCBG86951
D4HUC7pfkA89.0699.690.0ATP-dependent 6-phosphofructokinaseCBA19050
P19642pafP88.8799.810.0Transcription RegulatorAAA24098
A0A0F6B5R4STM14_RS1529088.6099.680.0Formate hydrogenlyase subunit 3ACY89858
P19786aroA88.5399.770.03-Phosphoshikimate 1-carboxyvinyltransferaseCAD05378
P09158speE88.4298.620.0Polyamine aminopropyltransferaseAAC73232
P30745moaA88.1599.700.0GTP 3',8-cyclaseAAC73868
D4HYW4asnB87.9199.640.0Asparagine synthase BCBA20089
D5AF41IMPDH87.6399.800.0Inosine-5'-monophosphate dehydrogenaseADE32434
P0C0B9bglB87.5499.330.0Putative phospho--glucosidaseAAK33487
C5BEV2glyA87.5399.760.0Serine h ydroxymethyltra nsferaseACR70340
Q97S30metF87.4198.960.0Methionine biosynthesis enzymesAAK74739
B5F8I0ArgD87.3899.510.0Acetylornithine/succinyldiaminopimelate aminotransferaseACH49836
A0A0D6I3U0envC87.2995.560.0Determinants for intrinsic CAMP resistanceALE64165
Q8ZPL7fumC87.2698.930.0Fumarate hydratase class IIAAL20389
P08331cpdB87.1799.850.02_,3_-Cyclic phosphodiesteraseAAA97109
D4HUF7metB86.9498.970.0Cystathionine gamma-synthaseCBA19080
C6DC70clpB86.9399.880.0Chaperone proteinACT14164
P0AB24efeO86.9399.730.0Iron uptake system componentAAC74103
Q66A26pykF86.6099.790.0Part of the pyruvate - tricarboxylic acid cycle nodeCAH21544
Q9ZFU7EutR86.5399.430.0HTH-type transcriptional regulatorAAC78127
Q8ZRE1phoR86.5199.540.0Histidine kinaseAAL19352
Q8ZMX2pat86.4899.210.0acetyltransferaseAAL21545
A4VWH9Eno86.4499.540.0EnolaseABP90468
D4ICB6nlpI86.0599.660.0Tetratricopeptide lipoproteinEAM_3066
P25535ubiI86.0099.750.0Aerobic ubiquinone-8 synthaseBAA14327
C5BDL7frdA85.9898.670.0Fumarate reductaseACR67633
P33221purT85.8395.170.0Formate-dependent phosphoribosylglycinamide formyltransferaseAAA23861
A4VYE0gidA85.2698.750.0tRNA uridine 5-carboxymethylaminomethyl modification enzymeABP91129
P0A452recA85.1998.460.0DNA recombination and repairAAL00560
A0A0F6B5S3STM14_RS1532584.9999.730.0Hydrogenase expression/formation proteinACY89867
B5TQV9PGM84.9499.480.0phosphoglucomutaseACH87041
D4I2T0pgi84.8599.820.0Glucose-6-phosphate isomeraseCBA23505
D4I0H1carA84.8297.450.0Carbamoyl-phosphate synthase small chainCBA22700
D0ZX10sssB84.81100.000.0Secreted effector proteinACY88258
D4HYF4purL84.7999.920.0Phosphoribosylformylglycinamidine synthaseCBA22070
P40120mdoD84.7399.640.0Glucans biosynthesis protein DAAC74506
Q54001MdsABC84.7299.190.0Multidrug transporter of SalmonellaTOLC_SALEN
P21169speC84.6799.860.0Constitutive ornithine decarboxylaseAAC76002
D4HUI1ilvA84.6399.810.0Threonine dehydrataseCBA19104
Q8ZNK8yeiE84.3299.650.0Putative LysR family transcriptional regulatorAAL21105
Q8ZJN0pgm84.2799.610.02,3-Bisphosphoglycerate-independent phosphoglycerate mutaseCAL18753
P13738nhaA84.2499.490.0Antiporter geneAAA23448
A0A2A7U510cadB84.2099.770.0Lysine-dependent acid resistance (LDAR) system membrane proteinPEH73496
D4HUY5rpoN84.0799.790.0Sigma factor, regulating essential virulence gene expressionCBA19258
A0A0F6B1M0ydcR84.0498.740.0Putative transcriptional regulatorACY88406
D4I2T4metA83.8299.680.0Homoserine O-succinyltransferaseCBA23513
Q7CQF1hnr83.6899.700.0Regulators of systemic infectionQ7CQF1_SALTY
D4I4L2glmS83.5899.840.0Glucosamine-fructose-6-phosphateaminotransferaseCBA24212
C6DI95PccS1_00144183.5599.360.0Transcriptional regulator, LysR family, MetRACT15089
P76142lsrB83.2896.480.0Autoinducer-2 ABC transporter periplasmic binding proteinAAC74589
Q8G8P0IroD83.0999.510.0Catecholate siderophore esterasesAAN76096AF449499_2
A0A0F6B5S4STM14_RS1533083.0499.700.0Formate hydrogenlyase transcriptional activatorACY89868
P31545efeB82.90100.470.0Deferrochelatase/peroxidaseAAC74104
A4VY17pdh82.7999.410.0Pyruvate dehydrogenaseABP91006
D0ZKI3bcsA82.7899.540.0cellulose synthesis regulationACY90746
P17750katG82.7699.720.0CatalaseAAL22946
A4VWD1mnmE82.6799.340.0Central tRNA-modifying GTPaseABP90420
D4HWM2cysI382.3999.300.0Sulfite reductaseCBA19698
C5BF98mdh82.3799.680.0Malate dehydrogenaseACR67684
P31554LptD82.3299.750.0LPS-assembly proteinBAA34130
Q8Z4H3iroC82.3098.930.0Putative ABC transporter proteinAAO70240
Q8Z445barA81.9999.460.0AAO70423
Q6KD45iucD81.4199.770.0aerobactinACJ63516
A0A0F6B5P9STM14_RS1523081.3199.690.0NorR family transcriptional regulatorACY89843
Q8Z4H1iroN80.9499.590.0TonB-dependent outer membrane siderophore receptor proteinAAO70243
P58662rcsC1180.7899.680.0Sensor proteinAAL21172
H9L460katE80.58100.000.0CatalaseAAL20243
Q8ZQE4MacB80.5699.690.0ABC-Type Efux PumpAAL19878
P26469rfaC80.1996.540.0heptosyl transferaseAAL22571
Q8XDQ1katN80.0099.335.59e-180Effector proteinBAB35075
A0A0F6B5R1STM14_RS1527592.1699.616.72e-179Formate hydrogenlyase complex iron-sulfur subunitACY89855
A0A0F6B5S8STM14_RS1534583.4590.851.53e-178Manganese/iron ABC transporter ATP-binding proteinACY89872
P0AA16ompR100.0099.581.54e-177Transcriptional regulatorAAC76430
P07014sdhB97.4899.581.98e-177Succinate dehydrogenase iron-sulfur subunitAAA23896
A0A0F6B5S1STM14_RS1531588.6299.668.71e-177Hydrogenase assembly chaperoneACY89865
A0A0F6B5P8STM14_RS1522590.6699.618.58e-176Arabinose 5-phosphate isomeraseACY89842
P0A9Q1arcA97.0699.589.33e-175Aerobic respiration control proteinAAA97297
D2TR63artP93.8099.594.49e-173Arginine ABC transporter, ATP-binding proteinCBG87650
U6ZHA8kdgR88.5999.625.92e-173virulence negative regulatorsERO57666
P39832znuB92.3499.622.66e-171Zn(2(+)) ABC transporter membrane subunitAAC74929
P45610tonB99.1899.592.48e-170siderophores synthesisCAA48498
A0A0M2J080sufC90.7399.602.31e-169Sulfur mobilizationAPF09033
A0A0F6B5T0STM14_RS1535587.4594.432.51e-169Iron ABC transporter permeaseACY89874
C6DEY6rsmA81.6299.272.28e-168Ribosomal RNA small subunit methyltransferase AACT14650
P0A9X1znuC90.4099.213.07e-167Zn(2(+)) ABC transporter ATP binding subunitAAC74928
A0A086ITU0fimC100.0099.552.44e-166Molecular chaperoneAUU95693
A0A0F6B5S9STM14_RS1535081.4898.547.58e-166Iron ABC transporter permeaseACY89873
A0A518VKX7kduD84.1999.619.96e-1652-Dehydro-3-deoxy-D-gluconate 5-dehydrogenaseQHP58461
P0A2F2cob84.9398.911.96e-163nicotinamide adenine dinucleotide (NAD + )-dependent deacetylaseAAC78722
W9B383dedA100.0099.551.72e-159DedA family inner membrane proteinARA47408
P0A2T6crp100.0099.532.78e-159Regulators of systemic infectionCRP_SALTY
Q7CPD5tatC84.9499.625.03e-159Sec-independent protein translocaseAAL22819
Q8Z8K9entA85.6699.603.48e-1572,3-Dihydro-2,3-dihydroxybenzoate dehydrogenaseAAO69872
Q8GM84rcsB99.5499.544.23e-157govern the expression of cps and of the loci implicated in lipid A remodelingAAL25250
P0A1D7ClpP99.0399.529.23e-156proteolytic componentBAA94668
C9Y236FkpA88.1294.204.33e-155virulence factorCBA34185
Q8GM81rmpA98.0999.531.42e-154Regulator of mucoid phenotypeAAL25252
F5ZP95phoP93.2799.115.57e-154Virulence transcriptional regulatory proteinAEF07105
D2TU76cpxR95.6999.571.67e-153Two-component response regulatorCBG90542
P96058sirA93.1299.541.79e-153AAO68606
W9BQ45leuD100.0099.501.11e-1523-Isopropylmalate dehydratase small subunitAIT01850
P0AF26narJ86.3899.168.00e-152Nitrate reductase molybdenum cofactor assembly chaperoneAAC74310
P08870pyrE93.9099.531.58e-149Orotate phosphoribosyltransferaseAAL22592
Q93MY4covR84.6899.583.41e-149Responder proteinAAK71319
P43019sodA95.1599.529.66e-149Cytoplasmic superoxide dismutaseAAC43331
P11350narI90.6299.123.14e-147Respiratory nitrate reductase 1 gamma chainAAC74311
Q66EI1pdhR86.3391.764.66e-147Part of the pyruvate - tricarboxylic acid cycle nodeCAH19952
G3FT04MrkA99.5099.515.67e-146Ferrous iron transporterAEO27492
A0A0H3NDI1tsaA95.0099.509.40e-146PeroxiredoxinCBW16497
A0A0F6B1X1pspA92.3499.556.36e-144Phage-shock proteinACY88508
A0A0S3FFR9fimA100.0099.482.18e-141Fimbrial proteinAUU95694
P0A251ahpC99.4799.473.21e-141PeroxiredoxinAAL19559
Q5KQZ9magA99.4899.486.54e-141Contributes to K1 capsular polysaccharide (CPS) biosynthesisBAD86762
P0AF32narV82.7499.566.78e-139Respiratory nitrate reductase 2 gamma chainBAA15102
P64036EF-P97.3499.478.94e-139Elongation factorAAL23157
Q8ZMF9pimt88.9499.522.38e-138Protein isoaspartate methyl transferaseAAL21806
P66796QseB85.8499.553.07e-137Two-component system response regulatorCAD03009
B3VA60CovR81.6699.564.42e-137serves to repress GAS virulence factor-encoding genesACE75886
P0A2F0rpoE96.8699.484.79e-137Regulators of systemic infectionRPOE_SALT
A1ABF3RstA80.7594.442.04e-134Part of a two component regulatory systemABJ00993
B0LF83fimI100.0099.441.96e-132Pilin (type 1 fimbria component protein)ABW24954
P0A2F4sodB91.1999.482.10e-132Cytoplasmic superoxide dismutaseAAL20353
P08179purN83.4199.066.05e-132Phosphoribosylglycinamide formyltransferaseAAA83899
A0A0D6I7L0ppiA92.6398.951.40e-130Peptidyl-prolyl cis-trans isomeraseALD83590
A6T684pagP99.4290.532.98e-128AcyltransferaseABR76105
P60317ProQ85.1599.131.08e-127RNA chaperoneAAL20761
W9BND0yfiR100.0094.942.48e-126Negative regulator of YfiBNR systemCDO12935
Q6D4B5eda85.9299.071.51e-1242-Keto-3-deoxy-6-phosphogluconate aldolaseCAG75378
A0A0F6B5R2STM14_RS1528090.0099.451.68e-123Formate hydrogenlyase subunit 5ACY89856
A1AEN2LuxS93.5799.428.33e-123controller in the Quorum sensingABJ02122
P0AFV4MepS86.2499.474.35e-122Peptidoglycan DD-endopeptidase/peptidoglycan LD-carboxypeptidaseAAC75236
P0ACR9MprA92.5798.876.82e-122Transcriptional repressor of an operon encoding the EmrAB efflux pump.CAA38090
A0A0F7DI09ppiB94.5199.391.67e-117Peptidyl-prolyl cis-trans isomeraseALD83591
D3VBH2lrp96.9599.394.11e-117Global Transcription FactorCBJ89611
A0A0F6B5Q6STM14_RS1525590.7595.051.44e-115Hypothetical proteinACY89850
A0A0H3NC59yeaB82.2999.481.15e-114RNA methyltransferaseCBW17849
P0AC98satP87.2399.471.10e-113Succinate-acetate/proton symporterAAC73121
P0A2G1smpB94.3899.383.27e-113Regulators of systemic infectionSSRP_SALTY
P0AB06ycbK91.2699.455.20e-113Peptidoglycan LD-endopeptidaseAAC74012
A0A0T5I632fimF90.7199.458.63e-113Putative fimbrial subunitSBY39291
P23484fecI89.0299.433.92e-112RNA polymerase sigma factorAAA23766
P64281greA94.3099.373.29e-111Transcription elongation factorAAL22169
P0A1G5DksA98.6799.347.64e-111Response RegulatorAAD01437
D2TNF0argR94.2399.362.26e-107Arginine repressorCBG91281
Q8ZLJ2greB91.0899.371.08e-106Transcription elongation factorAAL22365
Q7CQY3fur96.0099.341.34e-106Ferric uptake regulation proteinAAL19637
D4I230hcp-282.2199.391.29e-102T6SS Effector proteinCBA23273
Q7CQ10iscR93.2998.792.49e-98Fe-S cluster sensorAAL21438
P0A917OmpX81.9898.262.27e-97Outer membrane proteinAAA66329
A6TAK8hns100.0099.268.45e-97pleiotropic regulatorABR77629
Q665I9ptsN85.0695.654.46e-96Part of the pyruvate - tricarboxylic acid cycle nodeCAH22766
A0A0F6B5Q9STM14_RS1526588.3998.733.78e-92Formate hydrogenlyase maturation proteinACY89853
A0A0L9JQ40iscU97.6699.223.24e-91Fe-S cluster sensorAPQ81541
A1JQ74ybeY81.8297.471.32e-89EndoribonucleaseCAL13026
A0A0F6B5R0STM14_RS1527087.5099.271.89e-88NADH-quinone oxidoreductase subunitACY89854
U2W9V3SpxA291.6799.255.91e-88Transcriptional regulatorERL21461
A6TF94arnF100.0099.216.80e-86Hypothetical proteinABR79228
A0A0F7J4C9tomB91.1399.209.29e-86Hha toxicity attenuatorAKH06147
P40676slyA84.0399.311.34e-85Regulators of systemic infectionSLYA_SALTY
P69054sdhC93.0299.236.70e-85Succinate dehydrogenaseAAA23893
Q57PB8MarA92.7496.881.93e-84Transcriptional regulatorAAX65443
Q8XBU9ybdB82.4899.282.21e-84Proofreading thioesteraseAE005239_7
A0A1C1TY69mdtJ99.1799.175.23e-78Multidrug transporter subunitAUY17561
Q57RZ3ramA90.2799.123.70e-76Transcriptional regulatorAAX64518
A6TF95arnE100.0099.129.86e-76Hypothetical proteinABR79229
Q6CZA0metJ96.1999.064.44e-75Repressor of the methionine biosynthesis regulonCAG77150
P0AC44sdhD90.4499.147.76e-71Succinate dehydrogenaseAAA23894
B5XR94mdtI97.2599.099.14e-71Multidrug resistance proteinACI10803
C6DIJ6PccS1_00152397.9698.991.47e-67Transcriptional regulator, Fis family, FisACT11296
P64394himD98.9297.892.77e-66Regulators of systemic infectionIHFB_SALTY
P0A1R0hfq91.2698.061.16e-64Regulators of systemic infectionHFQ_SALTY
D4HX89yfiA80.1898.231.89e-64CBA19780
A0A0F7DJX4ppiC92.4798.943.17e-60Peptidyl-prolyl cis-trans isomeraseALD83589
D0Z9U0hupA95.5698.906.32e-58Nucleoid-associated protein, is a basic DNA-binding protein involved in gene regulationACY83030
Q8DQV4spr047985.4297.962.23e-57essential geneAAK99283
E0SMW8clpS82.9887.851.46e-56ATP-dependent Clp protease adapter proteinADM98238
D4HXP5ptsH96.4798.847.61e-56Phosphocarrier protein HPrCBA21825
A0A0F6B5S2STM14_RS1532090.0098.901.31e-55Hydrogenase formation proteinACY89866
D4HUY4yhbH80.0098.962.06e-54a novel ribosome-associated modulation proteinCBA19257
Q8DP67spr132792.9498.845.76e-54essential geneAAL00131
P0AA34yedF96.1098.721.60e-52Hypothetical transcription factorAAL20878
Q8CZ89spr017585.2398.881.36e-51pathogenitcity relatedAAK98979
Q8DRE1spr017783.1587.255.21e-50essential geneAAK98981
Q7CR17hha98.6198.638.84e-50Hemolysin expression-modulating proteinAAL19427
Q8ZQ03ycfR84.7198.848.90e-48Outer membrane proteinAAL20143
A0A0U1J4N7yqiC89.8779.001.83e-46Membrane fusogenic activityCNQ39570
P0A9Y9cspC100.0098.574.54e-46Cold shock proteinAAC06037
A0A0F6AYC2cspE97.1098.571.73e-45Cold shock proteinACY87244
A0A0F6B1X0pspB81.0898.671.70e-42Phage-shock proteinACY88507
P69913csrA100.0098.398.56e-40Post-transcriptional regulatorAAA71919
A0A6C7HPB2SEN153893.3398.361.16e-33Conserved hypothetical proteinCAR33117
Q48412RomA (VK055_1984)98.1179.704.66e-72Metallo-beta-lactamase superfamily proteinAIK80590
W9B5X1ykfE (VK055_1949)99.3284.091.40e-108inhibitor of vertebrate C-type lysozymeAIK80555
D4I4J9EaAdeP (EAMY 3685)84.2698.630.0Putative AzgA family transporterCBA24187
W9B570FepA (VK055_1934)99.3786.000.0TonB-dependent siderophore receptor family proteinAIK80540
W9BF24EntA (VK055_1922)99.6095.800.02,3-Dihydro-2,3-dihydroxybenzoate dehydrogenaseAIK80528
Q9I0J4nuoI (PA2644)82.9596.173.65e-108NADH-quinone oxidoreductaseAE004693_3
A1JLB7RcsB (YE1397)91.4397.226.14e-142Transcriptional regulatory proteinCAL11489
A0A0F6B0X0STM14_RS07735 (lppB)84.8197.502.12e-41Hypothetical proteinACY88148
A0A0F6B0X1STM14_RS07740 (lpp)97.4498.731.54e-49Murein lipoproteinACY88149
P0AA28thioredoxin 197.2599.097.65e-76Redox activityBAA00903
A0A0F6B5P4STM14_RS15205 (slrB)81.6799.171.35e-67PTS glucitol/sorbitol transporter subunit IIAACY89838
A0A0F6B0W8STM14_RS07725 (ynhA/sufE)80.4499.281.10e-82Cysteine desulfuration proteinACY88146
A0A0F6B5P2STM14_RS15195 (srlA)93.0599.472.48e-131PTS sorbitol transporter subunit IICACY89836
B5Y006BetI (VK055_1951)100.0099.491.10e-144Transcriptional repressorAIK80557
B5XZZ0EntD (VK055_1935)92.8299.522.26e-1434'-Phosphopantetheinyl transferase superfamily proteinAIK80541
D2TUX9dsbA (ROD_38991)87.9299.524.10e-141Thiol:disulfide interchange proteinCBG90603
Q56056RNase III96.4699.563.30e-164endoribonucleasesAAA92440
A0A0F6B0W5STM14_RS07710 (sufC)90.7399.602.31e-169Fe-S cluster assembly ATPaseACY88143
W9B5Y9FepC (VK055_1930)100.0099.620.0Ferric vibriobactin ABC transporter, ATP-binding proteinAIK80536
A0A0F6B5P5STM14_RS15210 (srlD)91.8999.622.80e-177Sorbitol-6-phosphate dehydrogenaseACY89839
Q8X6J9ovrB (Z0346)84.6999.660.0LysR-type transcriptional regulatorAE005205_3
W9BFU2lpxL1 (BN49_2155)99.6799.670.0Lipid A late acyltransferaseATM55433
W9B4X1lpxL2 (BN49_1538)99.6799.670.0Lipid A late acyltransferaseAIT02281
W9BNM7FepD (VK055_1928)99.7099.700.0Ferric enterobactin transport system permeaseAIK80534
W9B576FepG (VK055_1929)99.7099.700.0Ferric enterobactin transport system permeaseAIK80535
Q04M32ilvC (SPD_0406)97.3599.710.0Ketol-acid reductoisomerase (NADP(+))ABJ55451
A0A086IIR8YbdK (VK055_1976)100.0099.730.0Gamma-glutamyl cysteine ligaseAIK80582
A0A085DFX7EntC (VK055_1925)99.7499.740.0Isochorismate synthaseAIK80531
A0A0F6B0W7STM14_RS07720 (sufS)81.0399.750.0Cysteine desulfuraseACY88145
A0A0F6B0X2STM14_RS07745 (pykF)96.1799.790.0Pyruvate kinase IACY88150
W9B580entE (VK055_1924)99.2599.810.0(2,3-dihydroxybenzoyl)adenylate synthaseAIK80530
E0SMW9clpA (Dda3937_02363)89.8799.870.0ATP-dependent Clp protease ATP-binding subunitADM98239
A0A0F6B5P3STM14_RS15200 (srlE)87.12100.310.0PTS sorbitol transporter subunit IIBACY89837
D2TI49degP (ROD_01651)90.98100.640.0Periplasmic serine endoprotease DegP-likeCBG86945
D4I3E6trpB92.0566.500.0Tryptophan synthase beta chainCBA20869
A0A8E5JM30acrD90.4763.680.0Resistance-nodulation-cell division (RND) transporterQUZ94265
W8ZK20yegN87.3660.810.0Multidrug efflux system subunitCDN82752
B5XZY6EntF (VK055_1931)98.6060.590.0Amino acid adenylation domain proteinAIK80537