Genome ID：GCA_015668115.1

Probiotic potential risk score

ARGs (CARD)	VFs (VFDB)	PGs (PHI-base)	PPRS
1	18	30	35.00

CARD

ARO accession	ARO name	Identity	Coverage	CARD name	Accession no.
ARO:3002687	catQ	94.06	100.00	catQ	M55620.1

Virulence Factor Database Search

Gene ID	Gene name	Identity	Coverage	e-value	VF name	VF category	Accession no.
VFG006087	STER_RS07100	96.25	99.52	0.0	Capsule	Immune modulation	WP_011681445
VFG006079	STER_RS07085	96.17	98.33	0.0	Capsule	Immune modulation	WP_011681442
VFG005556	tig/ropA	95.02	100.00	0.0	Trigger factor	Stress survival	WP_011680653
VFG005976	STER_RS05305	94.87	100.00	0.0	Capsule	Immune modulation	WP_011681174
VFG006081	rfbD	94.72	100.00	0.0	Capsule	Immune modulation	WP_014621820
VFG006031	STU_RS14630	93.93	100.00	0.0	Capsule	Immune modulation	WP_011226045
VFG006022	rfbB	93.89	100.00	0.0	Capsule	Immune modulation	WP_002947383
VFG005359	plr/gapA	93.87	100.10	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	WP_002899102
VFG006011	STER_RS05320	93.71	99.93	0.0	Capsule	Immune modulation	WP_011681177
VFG006075	STER_RS07075	92.28	100.00	0.0	Capsule	Immune modulation	WP_011681440
VFG006053	STU_RS14645	91.67	100.00	0.0	Capsule	Immune modulation	WP_011226048
VFG006046	STR_RS05880	91.41	100.00	0.0	Capsule	Immune modulation	WP_011226149
VFG005190	fbp54	91.08	99.94	0.0	FBPs	Adherence	WP_002952952
VFG006041	rfbA	90.92	100.00	0.0	Capsule	Immune modulation	WP_011681286
VFG005323	cbpD	90.77	99.29	0.0	Autolysin	Exoenzyme	WP_011225268
VFG005579	eno	90.58	100.00	0.0	Streptococcal enolase	Exoenzyme	WP_000022815
VFG006047	STU_RS14640	88.62	99.86	0.0	Capsule	Immune modulation	WP_011226047
VFG005382	srtA	84.93	99.87	0.0	Sortase A	Exoenzyme	WP_011681303

PHIB-BLAST

Protein ID	Gene name	Identity	Coverage	e-value	Function	Gene ID
Q1JLQ2	MntE	95.53	99.44	0.0	Manganese Homeostasis	ABF32167
P67331	spr0084	92.88	98.18	0.0	pathogenitcity related	AAK98888
Q1J943	prsA2	92.19	98.46	0.0	Ribose-phosphate pyrophosphokinase	ABF36968
Q97S31	metE	92.12	99.87	0.0	Methionine biosynthesis enzymes	AAK74738
Q99Z66	ptsI	89.95	99.83	0.0	Phosphoenolpyruvate-protein phosphotransferase	AAK34199
Q8DPC2	potA	89.84	99.48	0.0	ABC transporter ATP-binding protein - spermidine/putrescine transport	AAL00050
Q8DYL6	uvrB	89.59	99.85	0.0	Excinuclease ABC, B subunit	AE014259_2
D5AF41	IMPDH	87.83	99.80	0.0	Inosine-5'-monophosphate dehydrogenase	ADE32434
Q97S30	metF	87.76	98.96	0.0	Methionine biosynthesis enzymes	AAK74739
P0C0B9	bglB	87.54	99.33	0.0	Putative phospho--glucosidase	AAK33487
A4VWH9	Eno	86.44	99.54	0.0	Enolase	ABP90468
A4VYE0	gidA	85.58	98.75	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	ABP91129
P0A452	recA	85.19	98.46	0.0	DNA recombination and repair	AAL00560
B5TQV9	PGM	84.76	99.48	0.0	phosphoglucomutase	ACH87041
Q97RW0	SP_0676	83.44	93.50	0.0	Transcription facot	AAK74821
A4VY17	pdh	83.38	99.41	0.0	Pyruvate dehydrogenase	ABP91006
A4VWD1	mnmE	82.67	99.34	0.0	Central tRNA-modifying GTPase	ABP90420
A4VUT4	NisR	94.71	99.56	2.91e-161	Two-component signal-transduction systems	ABP89873
A4VUT3	NisK	91.49	99.58	2.54e-159	Two-component signal-transduction systems	ABP89872
Q93MY4	covR	85.53	99.58	4.30e-151	Responder protein	AAK71319
Q9S1K2	rr01	84.38	99.12	1.59e-144	Response regulator	CAB54566
R4Z8M6	ciaR	86.16	98.68	9.39e-144	Two component system response regulator	AIK75708
B3VA60	CovR	81.66	99.56	1.33e-137	serves to repress GAS virulence factor-encoding genes	ACE75886
U2W9V3	SpxA2	91.67	99.25	1.78e-88	Transcriptional regulator	ERL21461
U2UML5	SpxA1	82.84	99.26	1.64e-82	Transcriptional regulator	ERL19273
Q8DQV4	spr0479	85.42	97.96	6.69e-58	essential gene	AAK99283
Q8DP67	spr1327	92.94	98.84	1.73e-54	essential gene	AAL00131
Q8CZ89	spr0175	85.23	98.88	4.07e-52	pathogenitcity related	AAK98979
Q8DRE1	spr0177	83.15	87.25	1.56e-50	essential gene	AAK98981
Q04M32	ilvC (SPD_0406)	97.35	99.71	0.0	Ketol-acid reductoisomerase (NADP(+))	ABJ55451