Probiotic potential risk score
| ARGs (CARD) | VFs (VFDB) | PGs (PHI-base) | PPRS |
|---|---|---|---|
| 0 | 12 | 28 | 30.46 |
CARD
| ARO accession | ARO name | Identity | Coverage | CARD name | Accession no. |
|---|---|---|---|---|---|
| No hit found | |||||
Virulence Factor Database Search
| Gene ID | Gene name | Identity | Coverage | e-value | VF name | VF category | Accession no. |
|---|---|---|---|---|---|---|---|
| VFG005556 | tig/ropA | 94.78 | 100.00 | 0.0 | Trigger factor | Stress survival | WP_011680653 |
| VFG006089 | rfbD | 94.25 | 100.00 | 0.0 | Capsule | Immune modulation | WP_011681446 |
| VFG006022 | rfbB | 94.08 | 100.00 | 0.0 | Capsule | Immune modulation | WP_002947383 |
| VFG019077 | plr/gapA | 93.97 | 100.00 | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | WP_000260685 |
| VFG006000 | STER_RS05315 | 93.85 | 100.00 | 0.0 | Capsule | Immune modulation | WP_011681176 |
| VFG006046 | STR_RS05880 | 91.92 | 100.00 | 0.0 | Capsule | Immune modulation | WP_011226149 |
| VFG006041 | rfbA | 90.92 | 100.00 | 0.0 | Capsule | Immune modulation | WP_011681286 |
| VFG005579 | eno | 90.88 | 100.00 | 0.0 | Streptococcal enolase | Exoenzyme | WP_000022815 |
| VFG005323 | cbpD | 90.36 | 100.00 | 0.0 | Autolysin | Exoenzyme | WP_011225268 |
| VFG005190 | fbp54 | 90.07 | 99.88 | 0.0 | FBPs | Adherence | WP_002952952 |
| VFG006047 | STU_RS14640 | 88.62 | 99.86 | 0.0 | Capsule | Immune modulation | WP_011226047 |
| VFG005382 | srtA | 84.29 | 99.74 | 0.0 | Sortase A | Exoenzyme | WP_011681303 |
| VFG005964 | STER_RS05300 | 94.14 | 69.81 | 0.0 | Capsule | Immune modulation | WP_011681173 |
PHIB-BLAST
| Protein ID | Gene name | Identity | Coverage | e-value | Function | Gene ID |
|---|---|---|---|---|---|---|
| P67331 | spr0084 | 92.88 | 98.18 | 0.0 | pathogenitcity related | AAK98888 |
| Q97S31 | metE | 92.52 | 99.87 | 0.0 | Methionine biosynthesis enzymes | AAK74738 |
| Q1J943 | prsA2 | 92.19 | 98.46 | 0.0 | Ribose-phosphate pyrophosphokinase | ABF36968 |
| Q99Z66 | ptsI | 89.95 | 99.83 | 0.0 | Phosphoenolpyruvate-protein phosphotransferase | AAK34199 |
| Q8DPC2 | potA | 89.84 | 99.48 | 0.0 | ABC transporter ATP-binding protein - spermidine/putrescine transport | AAL00050 |
| Q8DYL6 | uvrB | 88.46 | 78.31 | 0.0 | Excinuclease ABC, B subunit | AE014259_2 |
| Q97S30 | metF | 88.11 | 98.96 | 0.0 | Methionine biosynthesis enzymes | AAK74739 |
| D5AF41 | IMPDH | 87.63 | 99.80 | 0.0 | Inosine-5'-monophosphate dehydrogenase | ADE32434 |
| P0C0B9 | bglB | 87.54 | 99.33 | 0.0 | Putative phospho--glucosidase | AAK33487 |
| A4VWH9 | Eno | 86.44 | 99.54 | 0.0 | Enolase | ABP90468 |
| A4VYE0 | gidA | 85.26 | 98.75 | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | ABP91129 |
| P0A452 | recA | 84.94 | 98.46 | 0.0 | DNA recombination and repair | AAL00560 |
| B5TQV9 | PGM | 84.76 | 99.48 | 0.0 | phosphoglucomutase | ACH87041 |
| Q97RW0 | SP_0676 | 83.44 | 93.50 | 0.0 | Transcription facot | AAK74821 |
| A4VY17 | pdh | 82.79 | 99.41 | 0.0 | Pyruvate dehydrogenase | ABP91006 |
| A4VWD1 | mnmE | 82.24 | 99.34 | 0.0 | Central tRNA-modifying GTPase | ABP90420 |
| A4VUT3 | NisK | 91.49 | 99.58 | 2.26e-159 | Two-component signal-transduction systems | ABP89872 |
| A4VUT4 | NisR | 93.39 | 99.56 | 2.24e-158 | Two-component signal-transduction systems | ABP89873 |
| Q93MY4 | covR | 85.11 | 99.58 | 1.32e-150 | Responder protein | AAK71319 |
| Q9S1K2 | rr01 | 84.38 | 99.12 | 1.41e-144 | Response regulator | CAB54566 |
| P0A4H7 | CiaR | 87.00 | 99.11 | 4.47e-143 | Two-component response regulator | AAK74935 |
| B3VA60 | CovR | 81.66 | 99.56 | 1.18e-137 | serves to repress GAS virulence factor-encoding genes | ACE75886 |
| U2W9V3 | SpxA2 | 91.67 | 99.25 | 1.58e-88 | Transcriptional regulator | ERL21461 |
| Q8DQV4 | spr0479 | 85.42 | 97.96 | 5.97e-58 | essential gene | AAK99283 |
| Q8DP67 | spr1327 | 92.94 | 98.84 | 1.54e-54 | essential gene | AAL00131 |
| Q8CZ89 | spr0175 | 85.23 | 98.88 | 3.63e-52 | pathogenitcity related | AAK98979 |
| Q8DRE1 | spr0177 | 83.15 | 87.25 | 1.40e-50 | essential gene | AAK98981 |
| Q04M32 | ilvC (SPD_0406) | 97.35 | 99.71 | 0.0 | Ketol-acid reductoisomerase (NADP(+)) | ABJ55451 |
| A0A2J9QCW3 | dltA | 82.49 | 65.18 | 0.0 | D-alanine--poly(phosphoribitol) ligase | PNM00420 |