Genome ID：GCA_903886745.1

Probiotic potential risk score

ARGs (CARD)	VFs (VFDB)	PGs (PHI-base)	PPRS
1	22	28	35.62

CARD

ARO accession	ARO name	Identity	Coverage	CARD name	Accession no.
ARO:3000192	tet(S)	99.84	100.78	tet(S)	L09756.1

Virulence Factor Database Search

Gene ID	Gene name	Identity	Coverage	e-value	VF name	VF category	Accession no.
VFG005382	srtA	99.87	100.00	0.0	Sortase A	Exoenzyme	WP_011681303
VFG006046	STR_RS05880	99.83	100.00	0.0	Capsule	Immune modulation	WP_011226149
VFG005191	fbp54	99.58	100.00	0.0	FBPs	Adherence	WP_011681101
VFG006086	STU_RS16250	99.48	100.00	0.0	Capsule	Immune modulation	WP_011226328
VFG006041	rfbA	99.42	100.00	0.0	Capsule	Immune modulation	WP_011681286
VFG005556	tig/ropA	99.22	100.00	0.0	Trigger factor	Stress survival	WP_011680653
VFG006022	rfbB	99.05	100.00	0.0	Capsule	Immune modulation	WP_002947383
VFG006084	STU_RS16245	99.01	100.00	0.0	Capsule	Immune modulation	WP_002948020
VFG006047	STU_RS14640	98.99	100.00	0.0	Capsule	Immune modulation	WP_011226047
VFG006088	STU_RS16255	98.87	100.00	0.0	Capsule	Immune modulation	WP_041828290
VFG006082	STU_RS16240	98.76	100.00	0.0	Capsule	Immune modulation	WP_011226326
VFG006090	STU_RS16260	98.65	95.25	0.0	Capsule	Immune modulation	WP_011226330
VFG006074	STU_RS16230	98.60	100.00	0.0	Capsule	Immune modulation	WP_011226325
VFG005325	cbpD	98.45	100.00	0.0	Autolysin	Exoenzyme	WP_011680595
VFG006011	STER_RS05320	98.08	100.00	0.0	Capsule	Immune modulation	WP_011681177
VFG006053	STU_RS14645	97.40	100.00	0.0	Capsule	Immune modulation	WP_011226048
VFG005976	STER_RS05305	97.03	100.00	0.0	Capsule	Immune modulation	WP_011681174
VFG006081	rfbD	96.95	100.00	0.0	Capsule	Immune modulation	WP_014621820
VFG006078	STU_RS16235	95.17	101.14	0.0	Capsule	Immune modulation	WP_002948022
VFG019077	plr/gapA	93.57	100.20	0.0	Streptococcal plasmin receptor/GAPDH	Adherence	WP_000260685
VFG006091	STU_RS16265	90.18	99.69	0.0	Capsule	Immune modulation	WP_011226331
VFG005580	eno	89.66	99.92	0.0	Streptococcal enolase	Exoenzyme	WP_000022813
VFG006031	STU_RS14630	93.95	69.88	0.0	Capsule	Immune modulation	WP_011226045

PHIB-BLAST

Protein ID	Gene name	Identity	Coverage	e-value	Function	Gene ID
Q1JLQ2	MntE	94.41	99.44	0.0	Manganese Homeostasis	ABF32167
P67331	spr0084	93.19	98.18	0.0	pathogenitcity related	AAK98888
Q97S31	metE	91.72	99.87	0.0	Methionine biosynthesis enzymes	AAK74738
Q1J943	prsA2	90.31	98.46	0.0	Ribose-phosphate pyrophosphokinase	ABF36968
Q8DPC2	potA	89.58	99.48	0.0	ABC transporter ATP-binding protein - spermidine/putrescine transport	AAL00050
Q8DYL6	uvrB	89.14	99.85	0.0	Excinuclease ABC, B subunit	AE014259_2
P0C0B9	bglB	88.89	99.33	0.0	Putative phospho--glucosidase	AAK33487
Q99Z66	ptsI	88.39	99.83	0.0	Phosphoenolpyruvate-protein phosphotransferase	AAK34199
D5AF41	IMPDH	87.63	99.80	0.0	Inosine-5'-monophosphate dehydrogenase	ADE32434
A4VWH9	Eno	85.75	99.54	0.0	Enolase	ABP90468
Q97S30	metF	85.31	98.96	0.0	Methionine biosynthesis enzymes	AAK74739
P0A452	recA	85.19	98.46	0.0	DNA recombination and repair	AAL00560
A4VYE0	gidA	85.10	98.75	0.0	tRNA uridine 5-carboxymethylaminomethyl modification enzyme	ABP91129
B5TQV9	PGM	83.71	99.48	0.0	phosphoglucomutase	ACH87041
Q97RW0	SP_0676	82.45	93.50	0.0	Transcription facot	AAK74821
A4VY17	pdh	82.20	99.41	0.0	Pyruvate dehydrogenase	ABP91006
A4VWD1	mnmE	80.92	99.34	0.0	Central tRNA-modifying GTPase	ABP90420
Q1JJJ3	PepO	80.19	99.84	0.0	Endopeptidase	ABF32980
Q93MY4	covR	84.25	99.58	1.63e-148	Responder protein	AAK71319
Q9S1K2	rr01	84.82	99.12	1.78e-145	Response regulator	CAB54566
P0A4H7	CiaR	87.00	99.11	1.68e-143	Two-component response regulator	AAK74935
B3VA60	CovR	81.06	98.69	4.35e-135	serves to repress GAS virulence factor-encoding genes	ACE75886
U2W9V3	SpxA2	89.39	99.25	3.10e-86	Transcriptional regulator	ERL21461
Q8DQV4	spr0479	85.42	97.96	2.30e-57	essential gene	AAK99283
Q8DP67	spr1327	95.29	98.84	4.35e-55	essential gene	AAL00131
Q8DRE1	spr0177	84.27	87.25	2.44e-51	essential gene	AAK98981
Q8CZ89	spr0175	84.09	98.88	4.48e-51	pathogenitcity related	AAK98979
Q04M32	ilvC (SPD_0406)	96.47	99.71	0.0	Ketol-acid reductoisomerase (NADP(+))	ABJ55451