Probiotic potential risk score
| ARGs (CARD) | VFs (VFDB) | PGs (PHI-base) | PPRS |
|---|---|---|---|
| 1 | 9 | 20 | 21.95 |
CARD
| ARO accession | ARO name | Identity | Coverage | CARD name | Accession no. |
|---|---|---|---|---|---|
| ARO:3000191 | tet(Q) | 96.65 | 100.00 | tet(Q) | Z21523.1 |
Virulence Factor Database Search
| Gene ID | Gene name | Identity | Coverage | e-value | VF name | VF category | Accession no. |
|---|---|---|---|---|---|---|---|
| VFG005359 | plr/gapA | 94.56 | 100.10 | 0.0 | Streptococcal plasmin receptor/GAPDH | Adherence | WP_002899102 |
| VFG006059 | STER_RS07055 | 92.67 | 74.81 | 0.0 | Capsule | Immune modulation | WP_011681436 |
| VFG006087 | STER_RS07100 | 92.62 | 99.68 | 0.0 | Capsule | Immune modulation | WP_011681445 |
| VFG006052 | rfbA | 91.43 | 76.32 | 0.0 | Capsule | Immune modulation | WP_011226150 |
| VFG005580 | eno | 90.90 | 74.02 | 0.0 | Streptococcal enolase | Exoenzyme | WP_000022813 |
| VFG005191 | fbp54 | 90.79 | 78.42 | 0.0 | FBPs | Adherence | WP_011681101 |
| VFG006067 | STER_RS07065 | 90.78 | 99.89 | 0.0 | Capsule | Immune modulation | WP_011681438 |
| VFG006077 | STR_RS06910 | 89.47 | 74.41 | 0.0 | Capsule | Immune modulation | WP_011227431 |
| VFG005382 | srtA | 84.53 | 99.87 | 0.0 | Sortase A | Exoenzyme | WP_011681303 |
| VFG006063 | STER_RS07060 | 92.80 | 61.59 | 0.0 | Capsule | Immune modulation | WP_011681437 |
PHIB-BLAST
| Protein ID | Gene name | Identity | Coverage | e-value | Function | Gene ID |
|---|---|---|---|---|---|---|
| Q1JLQ2 | MntE | 96.09 | 99.44 | 0.0 | Manganese Homeostasis | ABF32167 |
| Q1J943 | prsA2 | 92.19 | 98.46 | 0.0 | Ribose-phosphate pyrophosphokinase | ABF36968 |
| Q8DPC2 | potA | 89.84 | 99.48 | 0.0 | ABC transporter ATP-binding protein - spermidine/putrescine transport | AAL00050 |
| Q99Z66 | ptsI | 89.21 | 76.99 | 0.0 | Phosphoenolpyruvate-protein phosphotransferase | AAK34199 |
| D5AF41 | IMPDH | 87.83 | 99.80 | 0.0 | Inosine-5'-monophosphate dehydrogenase | ADE32434 |
| A4VYE0 | gidA | 87.58 | 75.59 | 0.0 | tRNA uridine 5-carboxymethylaminomethyl modification enzyme | ABP91129 |
| P0C0B9 | bglB | 87.54 | 99.33 | 0.0 | Putative phospho--glucosidase | AAK33487 |
| Q97S30 | metF | 87.06 | 98.96 | 0.0 | Methionine biosynthesis enzymes | AAK74739 |
| P0A452 | recA | 85.19 | 98.46 | 0.0 | DNA recombination and repair | AAL00560 |
| Q97RW0 | SP_0676 | 82.78 | 93.19 | 0.0 | Transcription facot | AAK74821 |
| Q93MY4 | covR | 85.53 | 99.58 | 3.61e-151 | Responder protein | AAK71319 |
| Q9S1K2 | rr01 | 83.93 | 99.12 | 1.18e-143 | Response regulator | CAB54566 |
| B3VA60 | CovR | 81.66 | 99.56 | 1.11e-137 | serves to repress GAS virulence factor-encoding genes | ACE75886 |
| U2W9V3 | SpxA2 | 91.67 | 99.25 | 1.49e-88 | Transcriptional regulator | ERL21461 |
| U2UML5 | SpxA1 | 82.09 | 99.26 | 6.18e-82 | Transcriptional regulator | ERL19273 |
| Q8DQV4 | spr0479 | 84.38 | 97.96 | 1.69e-56 | essential gene | AAK99283 |
| Q8DP67 | spr1327 | 92.94 | 98.84 | 1.45e-54 | essential gene | AAL00131 |
| Q8CZ89 | spr0175 | 85.23 | 98.88 | 3.42e-52 | pathogenitcity related | AAK98979 |
| Q8DRE1 | spr0177 | 83.15 | 87.25 | 1.31e-50 | essential gene | AAK98981 |
| Q04M32 | ilvC (SPD_0406) | 97.64 | 87.10 | 0.0 | Ketol-acid reductoisomerase (NADP(+)) | ABJ55451 |
| Q97S31 | metE | 92.77 | 68.27 | 0.0 | Methionine biosynthesis enzymes | AAK74738 |
| Q8DYL6 | uvrB | 87.64 | 67.02 | 0.0 | Excinuclease ABC, B subunit | AE014259_2 |
| P67331 | spr0084 | 94.76 | 69.60 | 2.02e-164 | pathogenitcity related | AAK98888 |
| Q7WYI8 | mtsA | 80.95 | 67.64 | 1.41e-123 | Substrate-binding lipoprotein of manganese transporter | AIK76191 |
| R4Z8M6 | ciaR | 83.67 | 64.76 | 6.66e-90 | Two component system response regulator | AIK75708 |