ORF_ID e_value Gene_name EC_number CAZy COGs Description
IFKFHHFF_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IFKFHHFF_00002 4.8e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IFKFHHFF_00003 1.1e-29 yyzM S Protein conserved in bacteria
IFKFHHFF_00004 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IFKFHHFF_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IFKFHHFF_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IFKFHHFF_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IFKFHHFF_00008 2.1e-61 divIC D Septum formation initiator
IFKFHHFF_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
IFKFHHFF_00011 3.8e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IFKFHHFF_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IFKFHHFF_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IFKFHHFF_00014 1.6e-134 L Transposase
IFKFHHFF_00015 1.1e-26 L transposase activity
IFKFHHFF_00016 1.8e-56 L transposition
IFKFHHFF_00017 2e-88 L Integrase core domain protein
IFKFHHFF_00030 5.3e-11
IFKFHHFF_00036 1.7e-140 mreC M Involved in formation and maintenance of cell shape
IFKFHHFF_00037 2.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IFKFHHFF_00038 5.5e-94 usp 3.5.1.28 CBM50 S CHAP domain
IFKFHHFF_00039 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IFKFHHFF_00040 5e-27
IFKFHHFF_00041 5.9e-219 araT 2.6.1.1 E Aminotransferase
IFKFHHFF_00042 7e-144 recO L Involved in DNA repair and RecF pathway recombination
IFKFHHFF_00043 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IFKFHHFF_00044 1.1e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IFKFHHFF_00045 6.8e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IFKFHHFF_00046 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IFKFHHFF_00047 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IFKFHHFF_00048 3.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IFKFHHFF_00049 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IFKFHHFF_00050 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IFKFHHFF_00051 1.2e-79 L transposase activity
IFKFHHFF_00052 2.6e-49 L transposition
IFKFHHFF_00053 6.3e-34 L Integrase core domain protein
IFKFHHFF_00054 1.4e-161 S CHAP domain
IFKFHHFF_00055 2e-241 purD 6.3.4.13 F Belongs to the GARS family
IFKFHHFF_00056 1.4e-75 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IFKFHHFF_00057 5e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IFKFHHFF_00058 1.1e-141 1.1.1.169 H Ketopantoate reductase
IFKFHHFF_00059 3.4e-24
IFKFHHFF_00060 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IFKFHHFF_00061 9.4e-183 L Transposase and inactivated derivatives IS30 family
IFKFHHFF_00062 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IFKFHHFF_00063 8.2e-70 argR K Regulates arginine biosynthesis genes
IFKFHHFF_00064 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IFKFHHFF_00065 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IFKFHHFF_00066 5.7e-36 S Protein of unknown function (DUF3021)
IFKFHHFF_00067 4.2e-62 KT phosphorelay signal transduction system
IFKFHHFF_00069 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IFKFHHFF_00071 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IFKFHHFF_00072 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
IFKFHHFF_00073 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
IFKFHHFF_00074 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IFKFHHFF_00075 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
IFKFHHFF_00081 2.6e-10
IFKFHHFF_00084 1.9e-07
IFKFHHFF_00089 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IFKFHHFF_00090 3.9e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IFKFHHFF_00091 5.5e-36 XK27_02060 S Transglycosylase associated protein
IFKFHHFF_00092 6.9e-43 badR K DNA-binding transcription factor activity
IFKFHHFF_00093 3.5e-97 S reductase
IFKFHHFF_00094 5.9e-38 L transposition
IFKFHHFF_00095 1.7e-41 L transposition
IFKFHHFF_00097 3.8e-78 yocD 3.4.17.13 V carboxypeptidase activity
IFKFHHFF_00098 1.4e-92 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IFKFHHFF_00100 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
IFKFHHFF_00101 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IFKFHHFF_00102 1.1e-83 S Putative small multi-drug export protein
IFKFHHFF_00103 6.2e-76 ctsR K Belongs to the CtsR family
IFKFHHFF_00104 0.0 clpC O Belongs to the ClpA ClpB family
IFKFHHFF_00105 1.3e-152 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IFKFHHFF_00106 4.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IFKFHHFF_00107 1.9e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IFKFHHFF_00108 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IFKFHHFF_00109 5.3e-144 S SseB protein N-terminal domain
IFKFHHFF_00110 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
IFKFHHFF_00111 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IFKFHHFF_00112 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IFKFHHFF_00115 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IFKFHHFF_00116 7.8e-85 yacP S RNA-binding protein containing a PIN domain
IFKFHHFF_00117 3.4e-155 degV S DegV family
IFKFHHFF_00119 4.2e-27 K helix-turn-helix
IFKFHHFF_00120 1.2e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IFKFHHFF_00121 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IFKFHHFF_00122 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IFKFHHFF_00123 4.1e-36 K sequence-specific DNA binding
IFKFHHFF_00125 0.0 S Lantibiotic dehydratase, C terminus
IFKFHHFF_00126 2.5e-231 spaC2 V Lanthionine synthetase C family protein
IFKFHHFF_00127 9.1e-124 EGP Major facilitator Superfamily
IFKFHHFF_00128 4.7e-36 EGP Major facilitator Superfamily
IFKFHHFF_00129 6.3e-93 3.6.4.12 K Divergent AAA domain protein
IFKFHHFF_00130 2.3e-226 int L Belongs to the 'phage' integrase family
IFKFHHFF_00131 1.8e-38 S Helix-turn-helix domain
IFKFHHFF_00133 9.4e-192
IFKFHHFF_00135 8.8e-43 isp2 S pathogenesis
IFKFHHFF_00136 5.8e-67 tnp L Transposase
IFKFHHFF_00137 5.8e-48 tnp L Transposase
IFKFHHFF_00138 2.1e-227 capA M Bacterial capsule synthesis protein
IFKFHHFF_00139 3.6e-39 gcvR T UPF0237 protein
IFKFHHFF_00140 1.7e-243 XK27_08635 S UPF0210 protein
IFKFHHFF_00141 5.2e-77 ais G alpha-ribazole phosphatase activity
IFKFHHFF_00142 4.7e-27 ais G alpha-ribazole phosphatase activity
IFKFHHFF_00143 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IFKFHHFF_00144 1.3e-102 acmA 3.2.1.17 NU amidase activity
IFKFHHFF_00145 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IFKFHHFF_00146 1.2e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IFKFHHFF_00147 7.5e-298 dnaK O Heat shock 70 kDa protein
IFKFHHFF_00148 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IFKFHHFF_00149 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IFKFHHFF_00150 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
IFKFHHFF_00151 1.6e-61 hmpT S membrane
IFKFHHFF_00164 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IFKFHHFF_00165 3.9e-170 L Transposase
IFKFHHFF_00166 9.9e-19 S Domain of unknown function (DUF4649)
IFKFHHFF_00167 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IFKFHHFF_00168 2.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IFKFHHFF_00169 1.3e-87
IFKFHHFF_00170 1.6e-77 sigH K DNA-templated transcription, initiation
IFKFHHFF_00171 9.3e-150 ykuT M mechanosensitive ion channel
IFKFHHFF_00172 4.9e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IFKFHHFF_00173 6.3e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IFKFHHFF_00174 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IFKFHHFF_00175 5.8e-85 XK27_03960 S Protein of unknown function (DUF3013)
IFKFHHFF_00176 4.8e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
IFKFHHFF_00177 1.8e-178 prmA J Ribosomal protein L11 methyltransferase
IFKFHHFF_00178 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IFKFHHFF_00179 1.1e-45 F nucleotide catabolic process
IFKFHHFF_00180 9.9e-141 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IFKFHHFF_00181 2.4e-141 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IFKFHHFF_00182 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IFKFHHFF_00183 1.8e-83 nrdI F Belongs to the NrdI family
IFKFHHFF_00184 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IFKFHHFF_00185 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IFKFHHFF_00186 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IFKFHHFF_00187 4e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IFKFHHFF_00188 1.2e-64 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IFKFHHFF_00189 3.9e-41 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IFKFHHFF_00190 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IFKFHHFF_00191 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IFKFHHFF_00192 3.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IFKFHHFF_00193 5.5e-201 yhjX P Major Facilitator
IFKFHHFF_00194 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IFKFHHFF_00195 5e-94 V VanZ like family
IFKFHHFF_00198 1e-123 glnQ E abc transporter atp-binding protein
IFKFHHFF_00199 1.5e-275 glnP P ABC transporter
IFKFHHFF_00200 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IFKFHHFF_00201 1.4e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IFKFHHFF_00202 3.8e-186 tagO 2.7.8.33, 2.7.8.35 M transferase
IFKFHHFF_00203 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IFKFHHFF_00204 1.4e-234 sufD O assembly protein SufD
IFKFHHFF_00205 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IFKFHHFF_00206 8.6e-75 nifU C SUF system FeS assembly protein, NifU family
IFKFHHFF_00207 5.9e-274 sufB O assembly protein SufB
IFKFHHFF_00208 2.4e-19 oppA E ABC transporter substrate-binding protein
IFKFHHFF_00209 1.9e-158 oppA E ABC transporter substrate-binding protein
IFKFHHFF_00210 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFKFHHFF_00211 8.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFKFHHFF_00212 7.9e-76 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFKFHHFF_00213 3.1e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IFKFHHFF_00214 6.1e-28 oppD P Belongs to the ABC transporter superfamily
IFKFHHFF_00215 6.5e-33 oppD P Belongs to the ABC transporter superfamily
IFKFHHFF_00216 1.8e-69 oppD P Belongs to the ABC transporter superfamily
IFKFHHFF_00217 3.9e-46 oppD P Belongs to the ABC transporter superfamily
IFKFHHFF_00218 3.9e-165 oppF P Belongs to the ABC transporter superfamily
IFKFHHFF_00221 6.6e-159 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IFKFHHFF_00222 1.6e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IFKFHHFF_00223 2.3e-119 K sequence-specific DNA binding
IFKFHHFF_00224 0.0 KLT serine threonine protein kinase
IFKFHHFF_00225 1.9e-223 EGP Major facilitator Superfamily
IFKFHHFF_00226 3.1e-72 adcR K transcriptional
IFKFHHFF_00227 1.3e-136 adcC P ABC transporter, ATP-binding protein
IFKFHHFF_00228 1.4e-131 adcB P ABC transporter (Permease
IFKFHHFF_00229 1.3e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IFKFHHFF_00230 1e-66 ptsG 2.7.1.199, 2.7.1.208 G pts system
IFKFHHFF_00231 5.6e-156 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
IFKFHHFF_00232 2.9e-108 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IFKFHHFF_00233 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
IFKFHHFF_00234 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
IFKFHHFF_00235 1.9e-127 yeeN K transcriptional regulatory protein
IFKFHHFF_00236 9.8e-50 yajC U protein transport
IFKFHHFF_00237 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IFKFHHFF_00238 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
IFKFHHFF_00239 1.9e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IFKFHHFF_00240 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IFKFHHFF_00241 0.0 WQ51_06230 S ABC transporter substrate binding protein
IFKFHHFF_00242 5.2e-142 cmpC S abc transporter atp-binding protein
IFKFHHFF_00243 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IFKFHHFF_00244 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IFKFHHFF_00245 1e-57 L transposase activity
IFKFHHFF_00246 9.6e-62 L transposition
IFKFHHFF_00247 4.8e-34 L Integrase core domain protein
IFKFHHFF_00250 4e-42
IFKFHHFF_00251 2.7e-28 J TM2 domain
IFKFHHFF_00252 5.6e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IFKFHHFF_00253 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IFKFHHFF_00254 7.4e-25 secE U Belongs to the SecE SEC61-gamma family
IFKFHHFF_00255 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
IFKFHHFF_00256 2.7e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
IFKFHHFF_00257 7e-56 cof Q phosphatase activity
IFKFHHFF_00258 3.3e-36 cof Q phosphatase activity
IFKFHHFF_00259 5.6e-138 glcR K transcriptional regulator (DeoR family)
IFKFHHFF_00260 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IFKFHHFF_00261 9.4e-183 L Transposase and inactivated derivatives IS30 family
IFKFHHFF_00262 1.7e-93 S thiolester hydrolase activity
IFKFHHFF_00263 8.1e-145 S COG1073 Hydrolases of the alpha beta superfamily
IFKFHHFF_00264 9.6e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IFKFHHFF_00265 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IFKFHHFF_00266 3.2e-77 yhaI L Membrane
IFKFHHFF_00267 6e-260 pepC 3.4.22.40 E aminopeptidase
IFKFHHFF_00268 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IFKFHHFF_00269 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IFKFHHFF_00270 3.1e-95 ypsA S Belongs to the UPF0398 family
IFKFHHFF_00271 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IFKFHHFF_00272 5.1e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IFKFHHFF_00273 0.0 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IFKFHHFF_00274 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
IFKFHHFF_00275 2.5e-23
IFKFHHFF_00276 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IFKFHHFF_00277 8.4e-84 XK27_09675 K -acetyltransferase
IFKFHHFF_00278 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IFKFHHFF_00279 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IFKFHHFF_00280 1e-59 L Integrase core domain protein
IFKFHHFF_00281 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IFKFHHFF_00282 1.2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IFKFHHFF_00283 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IFKFHHFF_00284 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
IFKFHHFF_00285 5.2e-98 ybhL S Belongs to the BI1 family
IFKFHHFF_00288 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IFKFHHFF_00289 2.8e-91 K transcriptional regulator
IFKFHHFF_00290 7.6e-36 yneF S UPF0154 protein
IFKFHHFF_00291 2.2e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IFKFHHFF_00292 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IFKFHHFF_00293 3.5e-99 XK27_09740 S Phosphoesterase
IFKFHHFF_00294 4.1e-86 ykuL S CBS domain
IFKFHHFF_00295 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IFKFHHFF_00296 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IFKFHHFF_00297 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IFKFHHFF_00298 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IFKFHHFF_00299 8.6e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IFKFHHFF_00300 1.2e-258 trkH P Cation transport protein
IFKFHHFF_00301 1.8e-248 trkA P Potassium transporter peripheral membrane component
IFKFHHFF_00302 9.4e-183 L Transposase and inactivated derivatives IS30 family
IFKFHHFF_00303 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IFKFHHFF_00304 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IFKFHHFF_00305 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
IFKFHHFF_00306 1.5e-161 K sequence-specific DNA binding
IFKFHHFF_00307 1.9e-33 V protein secretion by the type I secretion system
IFKFHHFF_00308 1.6e-109 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IFKFHHFF_00309 2e-36 V protein secretion by the type I secretion system
IFKFHHFF_00310 2.1e-64 comA V protein secretion by the type I secretion system
IFKFHHFF_00311 1.4e-69 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IFKFHHFF_00312 3.7e-51 yhaI L Membrane
IFKFHHFF_00313 4.7e-105 S Domain of unknown function (DUF4173)
IFKFHHFF_00314 6.8e-95 ureI S AmiS/UreI family transporter
IFKFHHFF_00315 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IFKFHHFF_00316 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IFKFHHFF_00317 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IFKFHHFF_00318 6.6e-78 ureE O enzyme active site formation
IFKFHHFF_00319 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IFKFHHFF_00320 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IFKFHHFF_00321 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IFKFHHFF_00322 6e-177 cbiM P PDGLE domain
IFKFHHFF_00323 1.7e-137 P cobalt transport protein
IFKFHHFF_00324 1.6e-131 cbiO P ABC transporter
IFKFHHFF_00325 6.9e-153 ET amino acid transport
IFKFHHFF_00326 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFKFHHFF_00327 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
IFKFHHFF_00328 3.8e-205 EGP Transmembrane secretion effector
IFKFHHFF_00329 1.8e-153 ET amino acid transport
IFKFHHFF_00330 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
IFKFHHFF_00331 1.3e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IFKFHHFF_00332 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IFKFHHFF_00333 9e-65 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IFKFHHFF_00334 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IFKFHHFF_00335 3e-98 metI P ABC transporter (Permease
IFKFHHFF_00336 2.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IFKFHHFF_00337 5.2e-33 salL 2.5.1.63, 2.5.1.94 F Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
IFKFHHFF_00338 2.6e-109 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
IFKFHHFF_00339 5.3e-27 P Psort location CytoplasmicMembrane, score
IFKFHHFF_00340 1.2e-36 P Psort location CytoplasmicMembrane, score
IFKFHHFF_00341 2.8e-38 ykoD P ATPase activity
IFKFHHFF_00342 5e-265 ykoD P abc transporter atp-binding protein
IFKFHHFF_00343 9.4e-12 cbiQ P cobalt transport
IFKFHHFF_00344 3e-93 cbiQ P cobalt transport
IFKFHHFF_00345 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IFKFHHFF_00346 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
IFKFHHFF_00347 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
IFKFHHFF_00348 4.2e-245 P COG0168 Trk-type K transport systems, membrane components
IFKFHHFF_00349 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
IFKFHHFF_00350 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
IFKFHHFF_00351 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFKFHHFF_00352 2.8e-282 T PhoQ Sensor
IFKFHHFF_00353 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IFKFHHFF_00354 1.3e-218 dnaB L Replication initiation and membrane attachment
IFKFHHFF_00355 4e-167 dnaI L Primosomal protein DnaI
IFKFHHFF_00356 1.1e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IFKFHHFF_00357 3.5e-283 P ABC transporter transmembrane region
IFKFHHFF_00359 1e-223 L Transposase
IFKFHHFF_00360 9.8e-25 S Protein of unknown function DUF262
IFKFHHFF_00361 4.6e-233 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IFKFHHFF_00362 5e-63 manO S protein conserved in bacteria
IFKFHHFF_00363 1.1e-169 manN G PTS system mannose fructose sorbose family IID component
IFKFHHFF_00364 2.7e-117 manM G pts system
IFKFHHFF_00365 7.5e-183 manL 2.7.1.191 G pts system
IFKFHHFF_00366 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
IFKFHHFF_00367 2.1e-151 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IFKFHHFF_00368 1.5e-248 pbuO S permease
IFKFHHFF_00369 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
IFKFHHFF_00370 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
IFKFHHFF_00371 2.5e-220 brpA K Transcriptional
IFKFHHFF_00372 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
IFKFHHFF_00373 4.1e-212 nusA K Participates in both transcription termination and antitermination
IFKFHHFF_00374 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
IFKFHHFF_00375 1.4e-41 ylxQ J ribosomal protein
IFKFHHFF_00376 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IFKFHHFF_00377 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IFKFHHFF_00378 2.1e-48 yvdD 3.2.2.10 S cytokinin biosynthetic process
IFKFHHFF_00379 4e-26 yvdD 3.2.2.10 S cytokinin biosynthetic process
IFKFHHFF_00381 7.4e-236 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
IFKFHHFF_00382 2.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IFKFHHFF_00383 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
IFKFHHFF_00384 1.1e-77 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
IFKFHHFF_00385 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
IFKFHHFF_00386 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IFKFHHFF_00387 4e-09 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
IFKFHHFF_00388 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IFKFHHFF_00389 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IFKFHHFF_00390 1.2e-74 ylbF S Belongs to the UPF0342 family
IFKFHHFF_00391 7.1e-46 ylbG S UPF0298 protein
IFKFHHFF_00392 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IFKFHHFF_00393 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
IFKFHHFF_00394 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
IFKFHHFF_00395 1.3e-137 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IFKFHHFF_00396 2.1e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IFKFHHFF_00397 1.5e-71 acuB S IMP dehydrogenase activity
IFKFHHFF_00398 3.3e-43 acuB S IMP dehydrogenase activity
IFKFHHFF_00399 2.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IFKFHHFF_00400 1.1e-110 yvyE 3.4.13.9 S YigZ family
IFKFHHFF_00401 1.7e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IFKFHHFF_00402 3.4e-123 comFC S Competence protein
IFKFHHFF_00403 9.4e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IFKFHHFF_00411 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
IFKFHHFF_00412 6.4e-108 S Domain of unknown function (DUF1803)
IFKFHHFF_00413 7.8e-102 ygaC J Belongs to the UPF0374 family
IFKFHHFF_00414 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
IFKFHHFF_00415 2.7e-260 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IFKFHHFF_00416 2.3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
IFKFHHFF_00417 3.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
IFKFHHFF_00418 4.3e-115 S HAD hydrolase, family IA, variant 3
IFKFHHFF_00419 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
IFKFHHFF_00420 1.4e-72 marR K Transcriptional regulator, MarR family
IFKFHHFF_00421 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IFKFHHFF_00422 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IFKFHHFF_00423 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
IFKFHHFF_00424 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IFKFHHFF_00425 1.3e-126 IQ reductase
IFKFHHFF_00426 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IFKFHHFF_00427 1.1e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IFKFHHFF_00428 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IFKFHHFF_00429 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IFKFHHFF_00430 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IFKFHHFF_00431 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IFKFHHFF_00432 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IFKFHHFF_00433 3.6e-128 tnp L Transposase
IFKFHHFF_00434 9.2e-207 rny D Endoribonuclease that initiates mRNA decay
IFKFHHFF_00435 1.2e-85 L Transposase
IFKFHHFF_00436 5.6e-114 fruR K transcriptional
IFKFHHFF_00437 3.4e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IFKFHHFF_00438 3.3e-124 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
IFKFHHFF_00439 1.8e-79 fruA 2.7.1.202 G phosphotransferase system
IFKFHHFF_00440 2.9e-52 fruA 2.7.1.202 G phosphotransferase system
IFKFHHFF_00441 3.8e-48 fruA 2.7.1.202 G phosphotransferase system
IFKFHHFF_00442 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IFKFHHFF_00443 2.8e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IFKFHHFF_00445 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IFKFHHFF_00446 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IFKFHHFF_00447 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IFKFHHFF_00448 2.1e-257 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IFKFHHFF_00449 1.1e-38 2.3.1.128 K acetyltransferase
IFKFHHFF_00450 6.4e-29 2.3.1.128 K acetyltransferase
IFKFHHFF_00451 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IFKFHHFF_00452 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IFKFHHFF_00453 2.1e-99 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IFKFHHFF_00454 1.3e-37 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IFKFHHFF_00455 2.6e-64 WQ51_03320 S cog cog4835
IFKFHHFF_00456 2.9e-31 XK27_08360 S lipid binding
IFKFHHFF_00457 6.9e-110 XK27_08360 T EDD domain protein, DegV family
IFKFHHFF_00458 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IFKFHHFF_00459 1.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IFKFHHFF_00460 0.0 yfmR S abc transporter atp-binding protein
IFKFHHFF_00461 8e-24 U response to pH
IFKFHHFF_00462 5.6e-129 3.6.1.13, 3.6.1.55 F Nudix family
IFKFHHFF_00463 1.3e-215 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
IFKFHHFF_00464 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IFKFHHFF_00465 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IFKFHHFF_00467 1.9e-77 K DNA-binding transcription factor activity
IFKFHHFF_00468 0.0 lmrA1 V abc transporter atp-binding protein
IFKFHHFF_00469 0.0 lmrA2 V abc transporter atp-binding protein
IFKFHHFF_00470 4.7e-123 sptS 2.7.13.3 T Histidine kinase
IFKFHHFF_00471 6.4e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IFKFHHFF_00472 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IFKFHHFF_00473 5.3e-161 cvfB S Protein conserved in bacteria
IFKFHHFF_00474 7.4e-35 yozE S Belongs to the UPF0346 family
IFKFHHFF_00475 4.6e-133 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
IFKFHHFF_00476 5.6e-63 rlpA M LysM domain protein
IFKFHHFF_00477 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
IFKFHHFF_00482 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IFKFHHFF_00483 5.2e-167 K transcriptional regulator (lysR family)
IFKFHHFF_00484 1.4e-186 coiA 3.6.4.12 S Competence protein
IFKFHHFF_00485 0.0 pepF E oligoendopeptidase F
IFKFHHFF_00486 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
IFKFHHFF_00487 1.2e-176 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
IFKFHHFF_00488 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IFKFHHFF_00489 4.6e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IFKFHHFF_00490 1.7e-92 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IFKFHHFF_00491 2e-42 S pathogenesis
IFKFHHFF_00492 1.5e-132 3.4.17.14, 3.5.1.28 NU amidase activity
IFKFHHFF_00493 5.3e-147 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IFKFHHFF_00494 2.4e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
IFKFHHFF_00495 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IFKFHHFF_00496 4e-223 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IFKFHHFF_00497 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IFKFHHFF_00498 9.7e-211 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IFKFHHFF_00499 2.9e-142 yxkH G deacetylase
IFKFHHFF_00500 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IFKFHHFF_00501 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IFKFHHFF_00502 7.2e-153 rarD S Transporter
IFKFHHFF_00503 2.2e-15 T peptidase
IFKFHHFF_00504 8.9e-14 coiA 3.6.4.12 S Competence protein
IFKFHHFF_00505 2.3e-53 S FMN binding
IFKFHHFF_00506 2.7e-54 S FMN binding
IFKFHHFF_00507 1.2e-54 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IFKFHHFF_00508 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IFKFHHFF_00509 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IFKFHHFF_00510 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
IFKFHHFF_00511 3.3e-78 atpF C ATP synthase F(0) sector subunit b
IFKFHHFF_00512 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IFKFHHFF_00513 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IFKFHHFF_00514 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IFKFHHFF_00515 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IFKFHHFF_00516 1.1e-64 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IFKFHHFF_00517 2.8e-230 ftsW D Belongs to the SEDS family
IFKFHHFF_00518 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IFKFHHFF_00519 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IFKFHHFF_00520 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IFKFHHFF_00521 6.4e-162 holB 2.7.7.7 L dna polymerase iii
IFKFHHFF_00522 1.2e-135 yaaT S stage 0 sporulation protein
IFKFHHFF_00523 9.5e-55 yabA L Involved in initiation control of chromosome replication
IFKFHHFF_00524 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IFKFHHFF_00525 5.8e-233 amt P Ammonium Transporter
IFKFHHFF_00526 6.6e-54 glnB K Belongs to the P(II) protein family
IFKFHHFF_00527 3.2e-105 mur1 NU mannosyl-glycoprotein
IFKFHHFF_00528 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
IFKFHHFF_00529 1.7e-108 nptA P sodium-dependent phosphate transmembrane transporter activity
IFKFHHFF_00530 1.4e-18 nptA P sodium-dependent phosphate transmembrane transporter activity
IFKFHHFF_00531 1.9e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IFKFHHFF_00532 8.7e-56
IFKFHHFF_00533 4.4e-26
IFKFHHFF_00534 8.4e-63
IFKFHHFF_00535 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IFKFHHFF_00536 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IFKFHHFF_00537 4.5e-39 ynzC S UPF0291 protein
IFKFHHFF_00538 1.8e-254 cycA E permease
IFKFHHFF_00539 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
IFKFHHFF_00540 1.5e-25 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IFKFHHFF_00541 5.8e-71 pts33BCA G pts system
IFKFHHFF_00542 8.5e-120 pts33BCA G pts system
IFKFHHFF_00543 1.1e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
IFKFHHFF_00544 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IFKFHHFF_00549 1.4e-167 fhuR K transcriptional regulator (lysR family)
IFKFHHFF_00550 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IFKFHHFF_00551 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IFKFHHFF_00552 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IFKFHHFF_00553 2.2e-227 pyrP F uracil Permease
IFKFHHFF_00554 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IFKFHHFF_00555 4.2e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
IFKFHHFF_00556 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
IFKFHHFF_00557 1.7e-134 J Putative SAM-dependent methyltransferase
IFKFHHFF_00558 2.5e-65 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IFKFHHFF_00559 1.1e-50 V efflux transmembrane transporter activity
IFKFHHFF_00560 1.1e-62 V efflux transmembrane transporter activity
IFKFHHFF_00561 8.2e-28 ytrF V efflux transmembrane transporter activity
IFKFHHFF_00563 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IFKFHHFF_00564 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IFKFHHFF_00566 0.0 mdlB V abc transporter atp-binding protein
IFKFHHFF_00567 0.0 lmrA V abc transporter atp-binding protein
IFKFHHFF_00568 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IFKFHHFF_00569 2.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IFKFHHFF_00570 1.5e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
IFKFHHFF_00571 1.9e-132 rr02 KT response regulator
IFKFHHFF_00572 1.9e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IFKFHHFF_00573 3.7e-168 V ABC transporter
IFKFHHFF_00574 5.4e-122 sagI S ABC-2 type transporter
IFKFHHFF_00575 3.1e-197 yceA S Belongs to the UPF0176 family
IFKFHHFF_00576 1.9e-29 XK27_00085 K Transcriptional
IFKFHHFF_00577 1.9e-22
IFKFHHFF_00578 1.7e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
IFKFHHFF_00579 6.6e-114 S VIT family
IFKFHHFF_00580 1.1e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IFKFHHFF_00581 3e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IFKFHHFF_00582 1.2e-17 ald 1.4.1.1 E alanine dehydrogenase activity
IFKFHHFF_00583 3.6e-45 ald 1.4.1.1 C Belongs to the AlaDH PNT family
IFKFHHFF_00584 3.6e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IFKFHHFF_00585 4.6e-105 GBS0088 J protein conserved in bacteria
IFKFHHFF_00586 3e-143 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IFKFHHFF_00587 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IFKFHHFF_00588 5e-179 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
IFKFHHFF_00589 5.2e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IFKFHHFF_00590 3.9e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IFKFHHFF_00591 4.5e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
IFKFHHFF_00592 6.4e-17
IFKFHHFF_00593 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IFKFHHFF_00595 3.5e-07 U protein secretion
IFKFHHFF_00596 5.5e-51 U protein secretion
IFKFHHFF_00598 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
IFKFHHFF_00599 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IFKFHHFF_00600 3.2e-20 XK27_13030
IFKFHHFF_00601 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IFKFHHFF_00602 7.4e-172 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IFKFHHFF_00603 4.3e-166 S Protein of unknown function (DUF3114)
IFKFHHFF_00604 3.6e-22 S Protein of unknown function (DUF3114)
IFKFHHFF_00605 3.6e-120 yqfA K protein, Hemolysin III
IFKFHHFF_00606 1.6e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IFKFHHFF_00607 1.7e-218 mvaS 2.3.3.10 I synthase
IFKFHHFF_00608 7.7e-168 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IFKFHHFF_00609 4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IFKFHHFF_00610 9.7e-22
IFKFHHFF_00611 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IFKFHHFF_00612 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IFKFHHFF_00613 4e-251 mmuP E amino acid
IFKFHHFF_00614 3.1e-178 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
IFKFHHFF_00615 1.4e-29 S Domain of unknown function (DUF1912)
IFKFHHFF_00616 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
IFKFHHFF_00617 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IFKFHHFF_00618 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IFKFHHFF_00619 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IFKFHHFF_00620 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
IFKFHHFF_00621 4.8e-16 S Protein of unknown function (DUF2969)
IFKFHHFF_00624 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
IFKFHHFF_00627 2.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
IFKFHHFF_00628 1.1e-30 S Domain of Unknown Function with PDB structure (DUF3862)
IFKFHHFF_00629 5.7e-71 M Pfam SNARE associated Golgi protein
IFKFHHFF_00630 4e-234 murN 2.3.2.10, 2.3.2.16 V FemAB family
IFKFHHFF_00631 7.8e-08 S oxidoreductase
IFKFHHFF_00632 7e-26 2.7.7.15 S inositol 2-dehydrogenase activity
IFKFHHFF_00633 1.4e-50 yvaA 1.1.1.371 S inositol 2-dehydrogenase activity
IFKFHHFF_00634 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
IFKFHHFF_00635 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IFKFHHFF_00636 0.0 clpE O Belongs to the ClpA ClpB family
IFKFHHFF_00637 1.6e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IFKFHHFF_00638 1.3e-34 ykuJ S protein conserved in bacteria
IFKFHHFF_00639 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
IFKFHHFF_00640 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
IFKFHHFF_00641 1.1e-78 feoA P FeoA domain protein
IFKFHHFF_00642 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IFKFHHFF_00643 6.6e-08
IFKFHHFF_00644 1.5e-35 yugF I carboxylic ester hydrolase activity
IFKFHHFF_00645 1.5e-23 I Alpha/beta hydrolase family
IFKFHHFF_00646 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IFKFHHFF_00647 1.2e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IFKFHHFF_00648 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
IFKFHHFF_00649 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IFKFHHFF_00650 5.8e-64 licT K transcriptional antiterminator
IFKFHHFF_00651 6.8e-53 licT K transcriptional antiterminator
IFKFHHFF_00652 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IFKFHHFF_00653 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IFKFHHFF_00654 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IFKFHHFF_00655 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IFKFHHFF_00656 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IFKFHHFF_00657 2.9e-221 mdtG EGP Major facilitator Superfamily
IFKFHHFF_00658 2e-33 secG U Preprotein translocase subunit SecG
IFKFHHFF_00659 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IFKFHHFF_00660 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IFKFHHFF_00661 5.7e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IFKFHHFF_00662 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
IFKFHHFF_00663 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
IFKFHHFF_00664 3.4e-183 ccpA K Catabolite control protein A
IFKFHHFF_00665 4e-27 yyaQ S YjbR
IFKFHHFF_00666 7.4e-146 yyaQ S YjbR
IFKFHHFF_00667 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IFKFHHFF_00668 1.3e-78 yueI S Protein of unknown function (DUF1694)
IFKFHHFF_00669 1.3e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IFKFHHFF_00670 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IFKFHHFF_00671 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
IFKFHHFF_00672 2.9e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IFKFHHFF_00673 3.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IFKFHHFF_00674 4.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IFKFHHFF_00675 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IFKFHHFF_00676 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IFKFHHFF_00677 3.2e-53 yheA S Belongs to the UPF0342 family
IFKFHHFF_00678 7.9e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IFKFHHFF_00679 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IFKFHHFF_00680 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IFKFHHFF_00681 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
IFKFHHFF_00682 5.4e-251 msrR K Transcriptional regulator
IFKFHHFF_00683 1.5e-161 ydiA P C4-dicarboxylate transporter malic acid transport
IFKFHHFF_00684 4.8e-204 I acyl-CoA dehydrogenase
IFKFHHFF_00685 2.7e-97 mip S hydroperoxide reductase activity
IFKFHHFF_00686 2.2e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IFKFHHFF_00687 1.1e-105
IFKFHHFF_00688 1.3e-31 K Cro/C1-type HTH DNA-binding domain
IFKFHHFF_00689 2.8e-16 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
IFKFHHFF_00690 5.8e-25 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
IFKFHHFF_00691 6.5e-17 estA E GDSL-like Lipase/Acylhydrolase
IFKFHHFF_00692 2.8e-95
IFKFHHFF_00693 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IFKFHHFF_00694 2.4e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IFKFHHFF_00695 2.4e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IFKFHHFF_00696 1.9e-189 S CRISPR-associated protein Csn2 subfamily St
IFKFHHFF_00697 3.4e-149 ycgQ S TIGR03943 family
IFKFHHFF_00698 3.4e-158 XK27_03015 S permease
IFKFHHFF_00700 0.0 yhgF K Transcriptional accessory protein
IFKFHHFF_00701 4.9e-86 ydcK S Belongs to the SprT family
IFKFHHFF_00702 2.9e-41 pspC KT PspC domain
IFKFHHFF_00703 8e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IFKFHHFF_00704 3.1e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IFKFHHFF_00706 1e-67 ytxH S General stress protein
IFKFHHFF_00708 3e-178 yegQ O Peptidase U32
IFKFHHFF_00709 3.4e-252 yegQ O Peptidase U32
IFKFHHFF_00710 5.8e-89 bioY S biotin synthase
IFKFHHFF_00712 1.1e-33 XK27_12190 S protein conserved in bacteria
IFKFHHFF_00713 2.4e-237 mntH P H( )-stimulated, divalent metal cation uptake system
IFKFHHFF_00714 2.4e-10
IFKFHHFF_00715 8.3e-69 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
IFKFHHFF_00716 0.0 L helicase
IFKFHHFF_00717 1.3e-131 L PLD-like domain
IFKFHHFF_00718 5.8e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IFKFHHFF_00719 1.9e-15 M LysM domain
IFKFHHFF_00720 9.7e-61 M LysM domain
IFKFHHFF_00721 1.9e-58 M LysM domain
IFKFHHFF_00722 7.6e-16
IFKFHHFF_00723 2.3e-175 S hydrolase
IFKFHHFF_00724 5.1e-116 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
IFKFHHFF_00725 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IFKFHHFF_00726 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
IFKFHHFF_00727 2.7e-27 P Hemerythrin HHE cation binding domain protein
IFKFHHFF_00728 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IFKFHHFF_00729 2.3e-10 MA20_36090 S Protein of unknown function (DUF2974)
IFKFHHFF_00730 2.7e-37 MA20_36090 S Protein of unknown function (DUF2974)
IFKFHHFF_00731 1.8e-136 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IFKFHHFF_00732 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IFKFHHFF_00733 5.4e-308 S AAA domain, putative AbiEii toxin, Type IV TA system
IFKFHHFF_00735 5.1e-226 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
IFKFHHFF_00736 0.0 S KAP family P-loop domain
IFKFHHFF_00737 6.1e-137 S Protein conserved in bacteria
IFKFHHFF_00738 5.1e-306 hsdM 2.1.1.72 V type I restriction-modification system
IFKFHHFF_00739 3e-12 S double-stranded DNA endodeoxyribonuclease activity
IFKFHHFF_00740 4.5e-26 S PD-(D/E)XK nuclease family transposase
IFKFHHFF_00741 2.8e-177 spd F DNA RNA non-specific endonuclease
IFKFHHFF_00742 1.5e-92 lemA S LemA family
IFKFHHFF_00743 7.3e-145 htpX O Belongs to the peptidase M48B family
IFKFHHFF_00744 4.2e-75 S Psort location CytoplasmicMembrane, score
IFKFHHFF_00745 6.2e-56 S Domain of unknown function (DUF4430)
IFKFHHFF_00746 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IFKFHHFF_00747 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
IFKFHHFF_00748 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
IFKFHHFF_00749 2.5e-197 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
IFKFHHFF_00750 3e-116 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IFKFHHFF_00751 1.6e-91 dps P Belongs to the Dps family
IFKFHHFF_00752 1.1e-80 perR P Belongs to the Fur family
IFKFHHFF_00753 1.1e-161 L Transposase and inactivated derivatives IS30 family
IFKFHHFF_00754 8.4e-28 yqgQ S protein conserved in bacteria
IFKFHHFF_00755 2.2e-179 glk 2.7.1.2 G Glucokinase
IFKFHHFF_00756 0.0 typA T GTP-binding protein TypA
IFKFHHFF_00758 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IFKFHHFF_00759 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IFKFHHFF_00760 2.2e-178 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IFKFHHFF_00761 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IFKFHHFF_00762 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IFKFHHFF_00763 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IFKFHHFF_00764 2.3e-96 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IFKFHHFF_00765 8.8e-35 yggT D integral membrane protein
IFKFHHFF_00766 7.2e-144 ylmH T S4 RNA-binding domain
IFKFHHFF_00767 7.9e-136 divIVA D Cell division protein DivIVA
IFKFHHFF_00768 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IFKFHHFF_00769 1.2e-17
IFKFHHFF_00770 3.8e-10
IFKFHHFF_00771 4.5e-222 mntH P Mn2 and Fe2 transporters of the NRAMP family
IFKFHHFF_00772 2e-45 rpmE2 J 50S ribosomal protein L31
IFKFHHFF_00773 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IFKFHHFF_00774 1.5e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
IFKFHHFF_00775 3.1e-155 gst O Glutathione S-transferase
IFKFHHFF_00776 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IFKFHHFF_00777 2.4e-112 tdk 2.7.1.21 F thymidine kinase
IFKFHHFF_00778 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IFKFHHFF_00779 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IFKFHHFF_00780 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IFKFHHFF_00781 1.4e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IFKFHHFF_00782 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
IFKFHHFF_00783 2.4e-107 pvaA M lytic transglycosylase activity
IFKFHHFF_00784 0.0 yfiB1 V abc transporter atp-binding protein
IFKFHHFF_00785 0.0 XK27_10035 V abc transporter atp-binding protein
IFKFHHFF_00786 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
IFKFHHFF_00787 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFKFHHFF_00788 4.6e-238 dltB M Membrane protein involved in D-alanine export
IFKFHHFF_00789 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IFKFHHFF_00790 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IFKFHHFF_00791 6.3e-34 L Integrase core domain protein
IFKFHHFF_00792 9.6e-32 L transposition
IFKFHHFF_00793 1.3e-54 L transposition
IFKFHHFF_00794 2.6e-09 L transposase activity
IFKFHHFF_00795 1.4e-46 L transposase activity
IFKFHHFF_00796 0.0 3.6.3.8 P cation transport ATPase
IFKFHHFF_00797 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
IFKFHHFF_00799 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IFKFHHFF_00800 7.3e-166 metF 1.5.1.20 C reductase
IFKFHHFF_00801 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IFKFHHFF_00802 1.7e-94 panT S ECF transporter, substrate-specific component
IFKFHHFF_00803 5.7e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IFKFHHFF_00804 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
IFKFHHFF_00805 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IFKFHHFF_00806 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFKFHHFF_00807 2.8e-40 T PhoQ Sensor
IFKFHHFF_00808 1.7e-43 T PhoQ Sensor
IFKFHHFF_00809 1.9e-127 T PhoQ Sensor
IFKFHHFF_00810 1.2e-165 L integrase core domain
IFKFHHFF_00811 3.9e-122 L Transposase
IFKFHHFF_00812 2.1e-30 rpsT J rRNA binding
IFKFHHFF_00813 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
IFKFHHFF_00814 2.3e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
IFKFHHFF_00815 6.9e-26 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
IFKFHHFF_00816 1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
IFKFHHFF_00817 4.5e-59 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IFKFHHFF_00818 8.6e-65 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
IFKFHHFF_00819 6e-21 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IFKFHHFF_00820 4.8e-64 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IFKFHHFF_00821 4.7e-57 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IFKFHHFF_00822 7.3e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IFKFHHFF_00823 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IFKFHHFF_00824 8e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
IFKFHHFF_00825 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
IFKFHHFF_00826 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IFKFHHFF_00827 2.6e-305 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IFKFHHFF_00828 2.3e-142 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IFKFHHFF_00829 6.8e-81 ypmB S Protein conserved in bacteria
IFKFHHFF_00830 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IFKFHHFF_00831 1.3e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IFKFHHFF_00832 1.4e-18
IFKFHHFF_00833 5.4e-22
IFKFHHFF_00834 3.3e-12
IFKFHHFF_00835 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
IFKFHHFF_00836 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IFKFHHFF_00837 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
IFKFHHFF_00838 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IFKFHHFF_00839 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IFKFHHFF_00840 7.7e-20 D nuclear chromosome segregation
IFKFHHFF_00841 7.4e-138 yejC S cyclic nucleotide-binding protein
IFKFHHFF_00842 1.2e-163 rapZ S Displays ATPase and GTPase activities
IFKFHHFF_00843 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IFKFHHFF_00844 8.7e-162 whiA K May be required for sporulation
IFKFHHFF_00845 2.8e-90 pepD E Dipeptidase
IFKFHHFF_00846 5.8e-41 pepD E dipeptidase activity
IFKFHHFF_00847 2.4e-32 cspD K Cold shock
IFKFHHFF_00848 9.4e-43 K Cold-Shock Protein
IFKFHHFF_00849 3.6e-224 L Transposase
IFKFHHFF_00850 0.0 copB 3.6.3.4 P P-type ATPase
IFKFHHFF_00851 9.1e-101 L Transposase
IFKFHHFF_00852 1.3e-54 L Transposase
IFKFHHFF_00853 1.4e-195 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IFKFHHFF_00854 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IFKFHHFF_00855 5.4e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IFKFHHFF_00856 3.6e-100 cysE 2.3.1.30 E serine acetyltransferase
IFKFHHFF_00857 3.9e-223 L Transposase
IFKFHHFF_00858 1.6e-57 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
IFKFHHFF_00859 1.1e-115 hsdM 2.1.1.72 V type I restriction-modification system
IFKFHHFF_00860 7.4e-158 glcU U Glucose uptake
IFKFHHFF_00861 2e-07 mycA 4.2.1.53 S Myosin-crossreactive antigen
IFKFHHFF_00862 1.6e-57 V type I restriction-modification system
IFKFHHFF_00863 1.8e-90 XK27_10720 D peptidase activity
IFKFHHFF_00864 7.8e-296 adcA P Belongs to the bacterial solute-binding protein 9 family
IFKFHHFF_00865 1.7e-08
IFKFHHFF_00866 8.9e-81
IFKFHHFF_00867 2.5e-46
IFKFHHFF_00868 7.1e-17
IFKFHHFF_00869 9.3e-173 yeiH S Membrane
IFKFHHFF_00870 3.8e-84 mur1 NU amidase activity
IFKFHHFF_00871 3.6e-21 L transposase activity
IFKFHHFF_00872 4.1e-86 L transposition
IFKFHHFF_00873 2.6e-166 cpsY K Transcriptional regulator
IFKFHHFF_00874 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IFKFHHFF_00875 5.6e-58 phnA P Alkylphosphonate utilization operon protein PhnA
IFKFHHFF_00876 2.4e-105 artQ P ABC transporter (Permease
IFKFHHFF_00877 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
IFKFHHFF_00878 8.4e-159 aatB ET ABC transporter substrate-binding protein
IFKFHHFF_00879 5.8e-149 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IFKFHHFF_00880 2.1e-07
IFKFHHFF_00881 3.5e-25
IFKFHHFF_00882 4.6e-63 adhP 1.1.1.1 C alcohol dehydrogenase
IFKFHHFF_00883 1.8e-15 adhP 1.1.1.1 P alcohol dehydrogenase
IFKFHHFF_00884 2.4e-81 adhP 1.1.1.1 C alcohol dehydrogenase
IFKFHHFF_00885 2.7e-22
IFKFHHFF_00886 0.0 res_1 3.1.21.5 S Type III restriction
IFKFHHFF_00887 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
IFKFHHFF_00888 1.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IFKFHHFF_00889 1.6e-126 gntR1 K transcriptional
IFKFHHFF_00890 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IFKFHHFF_00891 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IFKFHHFF_00892 2.4e-87 niaX
IFKFHHFF_00893 6e-91 niaR S small molecule binding protein (contains 3H domain)
IFKFHHFF_00894 5.6e-129 K DNA-binding helix-turn-helix protein
IFKFHHFF_00895 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IFKFHHFF_00896 2.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IFKFHHFF_00897 3.7e-168 GK ROK family
IFKFHHFF_00898 8.3e-159 dprA LU DNA protecting protein DprA
IFKFHHFF_00899 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IFKFHHFF_00900 1.2e-165 L integrase core domain
IFKFHHFF_00901 3.9e-122 L Transposase
IFKFHHFF_00902 1e-153 S TraX protein
IFKFHHFF_00903 2.2e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFKFHHFF_00904 7.9e-255 T PhoQ Sensor
IFKFHHFF_00905 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IFKFHHFF_00906 6.2e-156 XK27_05470 E Methionine synthase
IFKFHHFF_00907 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IFKFHHFF_00908 3.6e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IFKFHHFF_00909 6.6e-54 IQ Acetoin reductase
IFKFHHFF_00910 3.9e-19 IQ Acetoin reductase
IFKFHHFF_00911 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IFKFHHFF_00915 1.1e-53 K peptidyl-tyrosine sulfation
IFKFHHFF_00916 6.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IFKFHHFF_00919 1.3e-212 pqqE C radical SAM domain protein
IFKFHHFF_00920 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
IFKFHHFF_00921 6.6e-61 EGP Major facilitator Superfamily
IFKFHHFF_00922 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IFKFHHFF_00923 2.3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IFKFHHFF_00924 1.9e-13
IFKFHHFF_00925 2.4e-181 L Transposase
IFKFHHFF_00926 4.6e-13 L Transposase
IFKFHHFF_00927 1.5e-22 V efflux transmembrane transporter activity
IFKFHHFF_00928 4.4e-95 V ABC transporter (Permease
IFKFHHFF_00929 3.5e-113 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IFKFHHFF_00930 1.6e-10
IFKFHHFF_00931 6.9e-98 K Transcriptional regulator, TetR family
IFKFHHFF_00932 2.3e-159 czcD P cation diffusion facilitator family transporter
IFKFHHFF_00933 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IFKFHHFF_00934 7.5e-135 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IFKFHHFF_00935 8.1e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
IFKFHHFF_00936 6e-08 S Hydrolases of the alpha beta superfamily
IFKFHHFF_00937 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
IFKFHHFF_00938 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
IFKFHHFF_00941 6.9e-144 2.4.2.3 F Phosphorylase superfamily
IFKFHHFF_00942 9.8e-120 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
IFKFHHFF_00943 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
IFKFHHFF_00944 1.2e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
IFKFHHFF_00945 5.3e-93 dinF V Mate efflux family protein
IFKFHHFF_00946 4.5e-36 dinF V drug transmembrane transporter activity
IFKFHHFF_00948 2.1e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IFKFHHFF_00950 9.7e-89 S TraX protein
IFKFHHFF_00951 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
IFKFHHFF_00952 1.5e-149 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IFKFHHFF_00953 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IFKFHHFF_00954 2.8e-111 cas1 L maintenance of DNA repeat elements
IFKFHHFF_00955 2.2e-69 cas1 L maintenance of DNA repeat elements
IFKFHHFF_00956 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IFKFHHFF_00957 6.8e-133 cas6 S Pfam:DUF2276
IFKFHHFF_00958 0.0 csm1 S CRISPR-associated protein Csm1 family
IFKFHHFF_00959 5.6e-62 csm2 L Pfam:DUF310
IFKFHHFF_00960 1.6e-117 csm3 L RAMP superfamily
IFKFHHFF_00961 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
IFKFHHFF_00962 1.5e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
IFKFHHFF_00963 3e-14 csm6 S Psort location Cytoplasmic, score
IFKFHHFF_00964 2.5e-64 csm6 S Psort location Cytoplasmic, score
IFKFHHFF_00965 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IFKFHHFF_00966 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IFKFHHFF_00968 9.3e-55 nylA 3.5.1.4 J Belongs to the amidase family
IFKFHHFF_00969 6.5e-268 dtpT E transporter
IFKFHHFF_00970 9.4e-183 L Transposase and inactivated derivatives IS30 family
IFKFHHFF_00971 2.2e-106 nylA 3.5.1.4 J Belongs to the amidase family
IFKFHHFF_00972 4.6e-73 yckB ET Belongs to the bacterial solute-binding protein 3 family
IFKFHHFF_00973 3.2e-59 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
IFKFHHFF_00974 3.3e-68 yecS P ABC transporter (Permease
IFKFHHFF_00975 9.2e-22 yecS P amino acid transport
IFKFHHFF_00977 3e-281 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
IFKFHHFF_00978 1.9e-38 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
IFKFHHFF_00979 1.2e-106 yfiF3 K sequence-specific DNA binding
IFKFHHFF_00980 2e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IFKFHHFF_00981 8.1e-241 agcS E (Alanine) symporter
IFKFHHFF_00982 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IFKFHHFF_00983 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
IFKFHHFF_00984 1.8e-59 Q phosphatase activity
IFKFHHFF_00985 9.3e-62 S haloacid dehalogenase-like hydrolase
IFKFHHFF_00986 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IFKFHHFF_00987 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
IFKFHHFF_00988 5.1e-139 XK27_04775 S hemerythrin HHE cation binding domain
IFKFHHFF_00989 5.2e-22 XK27_04775 P Hemerythrin HHE cation binding domain protein
IFKFHHFF_00990 8.4e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IFKFHHFF_00991 1.7e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IFKFHHFF_00992 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IFKFHHFF_00993 2.3e-44 yktA S Belongs to the UPF0223 family
IFKFHHFF_00994 6.5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IFKFHHFF_00995 6.1e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IFKFHHFF_00996 5.6e-158 pstS P phosphate
IFKFHHFF_00997 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
IFKFHHFF_00998 9.1e-156 pstA P phosphate transport system permease
IFKFHHFF_00999 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IFKFHHFF_01000 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IFKFHHFF_01001 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
IFKFHHFF_01002 0.0 pepN 3.4.11.2 E aminopeptidase
IFKFHHFF_01003 2.9e-196 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IFKFHHFF_01005 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
IFKFHHFF_01006 8.9e-08
IFKFHHFF_01007 3.2e-08
IFKFHHFF_01008 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IFKFHHFF_01009 5.3e-305 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
IFKFHHFF_01010 3.7e-182 malR K Transcriptional regulator
IFKFHHFF_01011 2e-19 malX G ABC transporter
IFKFHHFF_01012 4.5e-17 malX G maltose binding
IFKFHHFF_01013 1.8e-68 malX G maltose binding
IFKFHHFF_01014 1.3e-125 malF P ABC transporter (Permease
IFKFHHFF_01015 1.9e-13
IFKFHHFF_01016 4.6e-25 tatA U protein secretion
IFKFHHFF_01017 6.9e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IFKFHHFF_01018 3.1e-306 ywbL P COG0672 High-affinity Fe2 Pb2 permease
IFKFHHFF_01019 1.5e-233 ycdB P peroxidase
IFKFHHFF_01020 2.3e-151 ycdO P periplasmic lipoprotein involved in iron transport
IFKFHHFF_01021 2.6e-178 fatB P ABC-type enterochelin transport system, periplasmic component
IFKFHHFF_01022 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
IFKFHHFF_01023 1.5e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFKFHHFF_01024 1.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IFKFHHFF_01025 1.8e-30 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IFKFHHFF_01026 3.9e-113 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IFKFHHFF_01027 1.6e-210 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IFKFHHFF_01028 2.1e-207 L Transposase
IFKFHHFF_01029 1.7e-07 murA 2.5.1.7 M Belongs to the EPSP synthase family. MurA subfamily
IFKFHHFF_01030 2e-103 L nUDIX hydrolase
IFKFHHFF_01031 3.2e-172 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IFKFHHFF_01032 6.7e-156 K Transcriptional activator, Rgg GadR MutR family
IFKFHHFF_01033 4.6e-238 L Transposase
IFKFHHFF_01034 6.4e-69 3.2.1.17 M lysozyme activity
IFKFHHFF_01035 0.0 lpdA 1.8.1.4 C Dehydrogenase
IFKFHHFF_01036 4.2e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IFKFHHFF_01037 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IFKFHHFF_01038 4.6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IFKFHHFF_01039 4.6e-38 P membrane protein (DUF2207)
IFKFHHFF_01040 9.7e-65 S the current gene model (or a revised gene model) may contain a frame shift
IFKFHHFF_01041 2.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IFKFHHFF_01042 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IFKFHHFF_01043 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IFKFHHFF_01044 2.4e-23 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
IFKFHHFF_01045 5.3e-178 3.4.16.4 M Belongs to the peptidase S11 family
IFKFHHFF_01046 1.3e-159 rssA S Phospholipase, patatin family
IFKFHHFF_01047 4.6e-85 estA E GDSL-like protein
IFKFHHFF_01048 5.2e-295 S unusual protein kinase
IFKFHHFF_01049 1.3e-39 S granule-associated protein
IFKFHHFF_01050 1.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFKFHHFF_01051 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
IFKFHHFF_01052 5.1e-101 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFKFHHFF_01053 4.1e-29 bglH 3.2.1.86 GT1 G beta-glucosidase activity
IFKFHHFF_01054 7.7e-200 S hmm pf01594
IFKFHHFF_01055 1.6e-44 G alpha-ribazole phosphatase activity
IFKFHHFF_01056 4e-71 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
IFKFHHFF_01057 6.2e-97 V VanZ like family
IFKFHHFF_01058 1.1e-236 L Transposase
IFKFHHFF_01059 2e-114
IFKFHHFF_01060 5.1e-116 L Transposase
IFKFHHFF_01061 2.1e-111 U response to pH
IFKFHHFF_01062 3.4e-121 U response to pH
IFKFHHFF_01063 2.1e-32 L Transposase and inactivated derivatives
IFKFHHFF_01064 1.2e-143 S Core-2/I-Branching enzyme
IFKFHHFF_01065 3.4e-208 GT4 M Glycosyltransferase, group 1 family protein
IFKFHHFF_01066 1.7e-103 S Polysaccharide biosynthesis C-terminal domain
IFKFHHFF_01067 5.7e-206 M O-Antigen ligase
IFKFHHFF_01068 6.7e-268 S Sugar ISomerase
IFKFHHFF_01069 6.1e-193 2.4.1.308 GT11 S N-acetyllactosaminide 3-alpha-galactosyltransferase activity
IFKFHHFF_01070 1.4e-141 M Glycosyltransferase sugar-binding region containing DXD motif
IFKFHHFF_01071 2.4e-98 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
IFKFHHFF_01072 5.7e-22 M Glycosyl transferases group 1
IFKFHHFF_01073 4.2e-118 M Glycosyltransferase, group 1 family protein
IFKFHHFF_01074 1.9e-13 M Glycosyltransferase like family 2
IFKFHHFF_01075 4.5e-19 M Glycosyltransferase like family 2
IFKFHHFF_01076 1.2e-157 S Polysaccharide pyruvyl transferase
IFKFHHFF_01077 3.6e-10 GM Glycosyltransferase like family 2
IFKFHHFF_01078 2.8e-82 cysE 2.3.1.30 E Hexapeptide repeat of succinyl-transferase
IFKFHHFF_01079 7.6e-88 pssE S Glycosyltransferase family 28 C-terminal domain
IFKFHHFF_01080 2e-82 cpsF M Oligosaccharide biosynthesis protein Alg14 like
IFKFHHFF_01081 5e-87 cpsE M Bacterial sugar transferase
IFKFHHFF_01082 1.1e-76 cpsE M Bacterial sugar transferase
IFKFHHFF_01083 2.3e-259 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IFKFHHFF_01084 2.8e-118 cpsD D COG0489 ATPases involved in chromosome partitioning
IFKFHHFF_01085 5e-101 cps4C M biosynthesis protein
IFKFHHFF_01086 1.3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
IFKFHHFF_01087 3.6e-258 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
IFKFHHFF_01088 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
IFKFHHFF_01089 3.3e-45 yfeJ 6.3.5.2 F GMP synthase (glutamine-hydrolyzing) activity
IFKFHHFF_01090 1.3e-30 yfeJ 6.3.5.2 F GMP synthase (glutamine-hydrolyzing) activity
IFKFHHFF_01091 8.8e-66 clcA_2 P chloride channel
IFKFHHFF_01092 3e-13 clcA_2 P chloride
IFKFHHFF_01093 3.1e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IFKFHHFF_01094 2.3e-75 S Protein of unknown function (DUF1697)
IFKFHHFF_01095 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IFKFHHFF_01096 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IFKFHHFF_01098 3.7e-07 V Glucan-binding protein C
IFKFHHFF_01099 4.6e-238 L Transposase
IFKFHHFF_01100 4.6e-33 V Glucan-binding protein C
IFKFHHFF_01101 9.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
IFKFHHFF_01102 1.6e-276 pepV 3.5.1.18 E Dipeptidase
IFKFHHFF_01103 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IFKFHHFF_01104 1.4e-86 XK27_03610 K Gnat family
IFKFHHFF_01105 1.6e-24 L Transposase
IFKFHHFF_01106 6.2e-25 L Transposase
IFKFHHFF_01107 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IFKFHHFF_01108 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IFKFHHFF_01109 5.7e-89 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IFKFHHFF_01110 1.1e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IFKFHHFF_01111 5e-23 M LysM domain
IFKFHHFF_01112 2.9e-90 ebsA S Family of unknown function (DUF5322)
IFKFHHFF_01113 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IFKFHHFF_01114 3.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IFKFHHFF_01115 3.7e-224 G COG0457 FOG TPR repeat
IFKFHHFF_01116 2.7e-179 yubA S permease
IFKFHHFF_01117 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
IFKFHHFF_01118 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IFKFHHFF_01119 2.5e-124 ftsE D cell division ATP-binding protein FtsE
IFKFHHFF_01120 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IFKFHHFF_01121 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IFKFHHFF_01122 1.7e-164 yjjH S Calcineurin-like phosphoesterase
IFKFHHFF_01123 6.7e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IFKFHHFF_01124 0.0 pacL 3.6.3.8 P cation transport ATPase
IFKFHHFF_01125 2.6e-67 ywiB S Domain of unknown function (DUF1934)
IFKFHHFF_01126 1.7e-51 XK27_00115 2.3.1.128 K acetyltransferase
IFKFHHFF_01127 9.2e-147 yidA S hydrolases of the HAD superfamily
IFKFHHFF_01128 5.3e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
IFKFHHFF_01129 4.6e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
IFKFHHFF_01130 1.3e-235 vicK 2.7.13.3 T Histidine kinase
IFKFHHFF_01131 7.6e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFKFHHFF_01132 7.2e-141 glnQ 3.6.3.21 E abc transporter atp-binding protein
IFKFHHFF_01133 1.4e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IFKFHHFF_01134 2.7e-118 gltJ P ABC transporter (Permease
IFKFHHFF_01135 1.7e-111 tcyB_2 P ABC transporter (permease)
IFKFHHFF_01136 2e-142 endA F DNA RNA non-specific endonuclease
IFKFHHFF_01137 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
IFKFHHFF_01138 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IFKFHHFF_01139 2.6e-09 S Protein of unknown function (DUF1146)
IFKFHHFF_01140 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IFKFHHFF_01141 1.2e-14 G Domain of unknown function (DUF4832)
IFKFHHFF_01142 2.7e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IFKFHHFF_01143 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IFKFHHFF_01145 1.4e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IFKFHHFF_01146 9.4e-89 ytsP 1.8.4.14 T GAF domain-containing protein
IFKFHHFF_01147 1.3e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IFKFHHFF_01148 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
IFKFHHFF_01151 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IFKFHHFF_01152 5.5e-220 XK27_05110 P chloride
IFKFHHFF_01153 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
IFKFHHFF_01154 2e-283 clcA P Chloride transporter, ClC family
IFKFHHFF_01155 1.7e-60 fld C FMN binding
IFKFHHFF_01156 2.6e-08 XK27_08880
IFKFHHFF_01157 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
IFKFHHFF_01158 1.6e-151 estA CE1 S Putative esterase
IFKFHHFF_01159 2.1e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IFKFHHFF_01160 1.2e-135 XK27_08845 S abc transporter atp-binding protein
IFKFHHFF_01161 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
IFKFHHFF_01162 2.5e-178 XK27_08835 S ABC transporter substrate binding protein
IFKFHHFF_01163 3.2e-17 S Domain of unknown function (DUF4649)
IFKFHHFF_01165 2.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
IFKFHHFF_01166 6.3e-28 Q the current gene model (or a revised gene model) may contain a frame shift
IFKFHHFF_01168 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
IFKFHHFF_01170 3.5e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IFKFHHFF_01171 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IFKFHHFF_01172 0.0 dnaE 2.7.7.7 L DNA polymerase
IFKFHHFF_01173 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
IFKFHHFF_01174 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IFKFHHFF_01175 1.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IFKFHHFF_01176 1.3e-42 ysdA L Membrane
IFKFHHFF_01177 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IFKFHHFF_01178 2e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IFKFHHFF_01179 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IFKFHHFF_01180 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
IFKFHHFF_01182 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IFKFHHFF_01183 6.8e-96 ypmS S Protein conserved in bacteria
IFKFHHFF_01184 9e-148 ypmR E lipolytic protein G-D-S-L family
IFKFHHFF_01185 1.7e-148 DegV S DegV family
IFKFHHFF_01186 7.6e-305 recN L May be involved in recombinational repair of damaged DNA
IFKFHHFF_01187 7.5e-74 argR K arginine binding
IFKFHHFF_01188 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IFKFHHFF_01189 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IFKFHHFF_01190 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
IFKFHHFF_01191 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IFKFHHFF_01194 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IFKFHHFF_01195 2.9e-125 dnaD
IFKFHHFF_01196 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IFKFHHFF_01197 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IFKFHHFF_01198 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
IFKFHHFF_01199 2.3e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IFKFHHFF_01200 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IFKFHHFF_01201 7.9e-117 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IFKFHHFF_01202 1.9e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IFKFHHFF_01203 4.2e-243 rodA D Belongs to the SEDS family
IFKFHHFF_01204 2.1e-91 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IFKFHHFF_01205 7.9e-10 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IFKFHHFF_01206 2.6e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
IFKFHHFF_01207 1.8e-121 ylfI S tigr01906
IFKFHHFF_01208 1.7e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IFKFHHFF_01209 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
IFKFHHFF_01210 1.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
IFKFHHFF_01214 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IFKFHHFF_01215 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IFKFHHFF_01216 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IFKFHHFF_01217 1.3e-207 yurR 1.4.5.1 E oxidoreductase
IFKFHHFF_01218 1.1e-24 zupT P transporter
IFKFHHFF_01219 2.4e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
IFKFHHFF_01220 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IFKFHHFF_01221 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
IFKFHHFF_01222 1.3e-70 gtrA S GtrA-like protein
IFKFHHFF_01223 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IFKFHHFF_01224 6e-169 ybbR S Protein conserved in bacteria
IFKFHHFF_01225 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IFKFHHFF_01226 1.7e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
IFKFHHFF_01227 8.7e-150 cobQ S glutamine amidotransferase
IFKFHHFF_01228 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IFKFHHFF_01229 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
IFKFHHFF_01231 0.0 uup S abc transporter atp-binding protein
IFKFHHFF_01232 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
IFKFHHFF_01233 1.2e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
IFKFHHFF_01234 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IFKFHHFF_01235 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
IFKFHHFF_01236 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IFKFHHFF_01237 7.9e-39 ptsH G phosphocarrier protein Hpr
IFKFHHFF_01238 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
IFKFHHFF_01239 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
IFKFHHFF_01240 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IFKFHHFF_01241 2.2e-34 nrdH O Glutaredoxin
IFKFHHFF_01242 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IFKFHHFF_01243 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IFKFHHFF_01245 1.1e-74 L Transposase (IS116 IS110 IS902 family)
IFKFHHFF_01246 5.5e-65 L Transposase (IS116 IS110 IS902 family)
IFKFHHFF_01247 1.8e-165 ypuA S secreted protein
IFKFHHFF_01248 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
IFKFHHFF_01249 9.3e-59 srtA 3.4.22.70 M Sortase family
IFKFHHFF_01250 1.1e-59 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
IFKFHHFF_01251 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IFKFHHFF_01252 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IFKFHHFF_01253 2.6e-258 noxE P NADH oxidase
IFKFHHFF_01254 2.5e-294 yfmM S abc transporter atp-binding protein
IFKFHHFF_01255 5.4e-46 XK27_01265 S ECF-type riboflavin transporter, S component
IFKFHHFF_01256 5.4e-09 XK27_01265 S ECF-type riboflavin transporter, S component
IFKFHHFF_01257 5.5e-155 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IFKFHHFF_01258 2e-86 S ECF-type riboflavin transporter, S component
IFKFHHFF_01260 4.4e-58 XK27_08130 K transaminase activity
IFKFHHFF_01261 1.1e-149 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IFKFHHFF_01262 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
IFKFHHFF_01265 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IFKFHHFF_01266 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFKFHHFF_01267 3.3e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IFKFHHFF_01268 0.0 smc D Required for chromosome condensation and partitioning
IFKFHHFF_01269 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IFKFHHFF_01270 1.7e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IFKFHHFF_01271 1.2e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IFKFHHFF_01272 7.2e-91 alkD L Dna alkylation repair
IFKFHHFF_01273 2.8e-93 pat 2.3.1.183 M acetyltransferase
IFKFHHFF_01274 3.3e-12
IFKFHHFF_01275 9.6e-32
IFKFHHFF_01276 6.6e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IFKFHHFF_01277 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IFKFHHFF_01278 7.9e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
IFKFHHFF_01279 3.3e-66 bioY S biotin transmembrane transporter activity
IFKFHHFF_01280 3.6e-90 proW P Binding-protein-dependent transport system inner membrane component
IFKFHHFF_01281 1.5e-138 proV E abc transporter atp-binding protein
IFKFHHFF_01282 2e-169 proX M ABC transporter, substrate-binding protein, QAT family
IFKFHHFF_01283 3e-111 proWZ P ABC transporter (Permease
IFKFHHFF_01284 8.1e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
IFKFHHFF_01285 4.8e-207 S Protein of unknown function (DUF917)
IFKFHHFF_01286 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IFKFHHFF_01287 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
IFKFHHFF_01288 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
IFKFHHFF_01289 3.3e-26
IFKFHHFF_01290 3.4e-146 S ABC-2 family transporter protein
IFKFHHFF_01291 7.8e-100 S transport system, permease component
IFKFHHFF_01292 6.1e-103 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IFKFHHFF_01293 1.9e-195 desK 2.7.13.3 T Histidine kinase
IFKFHHFF_01294 9.6e-135 yvfS V ABC-2 type transporter
IFKFHHFF_01295 2.3e-159 XK27_09825 V abc transporter atp-binding protein
IFKFHHFF_01298 4.6e-166 yocS S Transporter
IFKFHHFF_01299 1.2e-84 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
IFKFHHFF_01300 2.6e-35 XK27_05000 S metal cluster binding
IFKFHHFF_01301 0.0 V ABC transporter (permease)
IFKFHHFF_01302 2.2e-134 macB2 V ABC transporter, ATP-binding protein
IFKFHHFF_01303 7.4e-167 T Histidine kinase
IFKFHHFF_01304 2.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IFKFHHFF_01305 3.4e-17 xpt 2.4.2.22, 2.4.2.7 F purine ribonucleoside salvage
IFKFHHFF_01306 1.4e-50 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IFKFHHFF_01308 2.6e-136 pbuX F xanthine permease
IFKFHHFF_01309 9e-248 norM V Multidrug efflux pump
IFKFHHFF_01310 2.5e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IFKFHHFF_01311 1.2e-165 L integrase core domain
IFKFHHFF_01312 1.5e-121 L Transposase
IFKFHHFF_01313 1.7e-235 brnQ E Component of the transport system for branched-chain amino acids
IFKFHHFF_01314 7.7e-67 manA 5.3.1.8 G mannose-6-phosphate isomerase
IFKFHHFF_01315 1.4e-59 manA 5.3.1.8 G mannose-6-phosphate isomerase
IFKFHHFF_01316 9.6e-26 csbD K CsbD-like
IFKFHHFF_01317 4.8e-228 yfnA E amino acid
IFKFHHFF_01318 1.3e-110 XK27_02070 S nitroreductase
IFKFHHFF_01319 2.2e-90 1.13.11.2 S glyoxalase
IFKFHHFF_01320 5.6e-77 ywnA K Transcriptional regulator
IFKFHHFF_01321 1.9e-158 E Alpha/beta hydrolase of unknown function (DUF915)
IFKFHHFF_01322 1.2e-233 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IFKFHHFF_01323 1.3e-111 drgA C Nitroreductase
IFKFHHFF_01324 1.7e-60 yoaK S Protein of unknown function (DUF1275)
IFKFHHFF_01326 3.1e-161 yvgN C reductase
IFKFHHFF_01327 5.5e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IFKFHHFF_01328 0.0 L DEAD-like helicases superfamily
IFKFHHFF_01329 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IFKFHHFF_01330 7.8e-285 XK27_07020 S Belongs to the UPF0371 family
IFKFHHFF_01332 6.7e-38 BP1961 P nitric oxide dioxygenase activity
IFKFHHFF_01333 4.4e-36 K the current gene model (or a revised gene model) may contain a frame shift
IFKFHHFF_01334 2.4e-54 K response regulator
IFKFHHFF_01335 1.3e-68 S Signal peptide protein, YSIRK family
IFKFHHFF_01337 7.6e-61
IFKFHHFF_01338 2.5e-272 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IFKFHHFF_01339 1.4e-139
IFKFHHFF_01340 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
IFKFHHFF_01341 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
IFKFHHFF_01342 5.8e-109 MA20_06410 E LysE type translocator
IFKFHHFF_01343 5.6e-08
IFKFHHFF_01344 2.7e-09
IFKFHHFF_01345 0.0 M family 8
IFKFHHFF_01346 1.8e-19
IFKFHHFF_01348 0.0 sbcC L ATPase involved in DNA repair
IFKFHHFF_01349 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IFKFHHFF_01350 0.0 lacL 3.2.1.23 G -beta-galactosidase
IFKFHHFF_01351 0.0 lacS G transporter
IFKFHHFF_01352 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IFKFHHFF_01353 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IFKFHHFF_01354 6.1e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IFKFHHFF_01355 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IFKFHHFF_01356 2.3e-184 galR K Transcriptional regulator
IFKFHHFF_01357 7.1e-09 L Integrase core domain protein
IFKFHHFF_01358 1.2e-25 L transposition
IFKFHHFF_01359 3e-198 M translation initiation factor activity
IFKFHHFF_01360 2.1e-68 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IFKFHHFF_01361 1.5e-77 V abc transporter atp-binding protein
IFKFHHFF_01362 1e-41 V (ABC) transporter
IFKFHHFF_01363 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
IFKFHHFF_01364 2.3e-87 L Transposase
IFKFHHFF_01365 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IFKFHHFF_01366 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IFKFHHFF_01367 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IFKFHHFF_01368 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IFKFHHFF_01371 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IFKFHHFF_01372 5.8e-175 vraS 2.7.13.3 T Histidine kinase
IFKFHHFF_01373 3.7e-120 yvqF KT membrane
IFKFHHFF_01374 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IFKFHHFF_01375 2e-132 stp 3.1.3.16 T phosphatase
IFKFHHFF_01376 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IFKFHHFF_01377 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IFKFHHFF_01378 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IFKFHHFF_01379 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
IFKFHHFF_01380 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IFKFHHFF_01381 1.8e-219 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IFKFHHFF_01382 6.9e-150 XK27_02985 S overlaps another CDS with the same product name
IFKFHHFF_01383 2.1e-148 supH S overlaps another CDS with the same product name
IFKFHHFF_01384 8.6e-63 yvoA_1 K Transcriptional
IFKFHHFF_01385 9.8e-121 skfE V abc transporter atp-binding protein
IFKFHHFF_01386 3.3e-133 V ATPase activity
IFKFHHFF_01387 4.3e-172 oppF P Belongs to the ABC transporter superfamily
IFKFHHFF_01388 2.2e-204 oppD P Belongs to the ABC transporter superfamily
IFKFHHFF_01389 4.9e-168 amiD P ABC transporter (Permease
IFKFHHFF_01390 7.1e-278 amiC P ABC transporter (Permease
IFKFHHFF_01391 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IFKFHHFF_01392 3.9e-237 L Transposase
IFKFHHFF_01393 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IFKFHHFF_01394 2.3e-84 oppF P Belongs to the ABC transporter superfamily
IFKFHHFF_01395 6.9e-22 tatD L hydrolase, TatD family'
IFKFHHFF_01396 1e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
IFKFHHFF_01397 1e-110 L PFAM Integrase catalytic region
IFKFHHFF_01398 9.3e-29 L transposition
IFKFHHFF_01399 4.3e-23 L transposase activity
IFKFHHFF_01400 3.3e-39 L transposase activity
IFKFHHFF_01401 1.7e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IFKFHHFF_01402 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IFKFHHFF_01403 4e-153 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IFKFHHFF_01404 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
IFKFHHFF_01405 1.5e-103 yjbK S Adenylate cyclase
IFKFHHFF_01406 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IFKFHHFF_01407 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
IFKFHHFF_01408 9e-59 XK27_04120 S Putative amino acid metabolism
IFKFHHFF_01409 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IFKFHHFF_01410 7.2e-132 puuD T peptidase C26
IFKFHHFF_01411 6.2e-120 radC E Belongs to the UPF0758 family
IFKFHHFF_01412 0.0 rgpF M Rhamnan synthesis protein F
IFKFHHFF_01413 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IFKFHHFF_01414 3e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IFKFHHFF_01415 2.8e-143 rgpC GM Transport permease protein
IFKFHHFF_01416 7.5e-180 rgpB GT2 M Glycosyltransferase, group 2 family protein
IFKFHHFF_01417 4.4e-227 rgpA GT4 M Domain of unknown function (DUF1972)
IFKFHHFF_01418 5.1e-195 tagF 2.7.8.12 M Glycosyl transferase, family 2
IFKFHHFF_01419 2.3e-224 amrA S polysaccharide biosynthetic process
IFKFHHFF_01420 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
IFKFHHFF_01421 3.4e-126 ycbB S Glycosyl transferase family 2
IFKFHHFF_01422 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IFKFHHFF_01423 9.9e-247
IFKFHHFF_01424 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
IFKFHHFF_01425 2e-253 M Psort location CytoplasmicMembrane, score
IFKFHHFF_01426 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
IFKFHHFF_01427 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IFKFHHFF_01428 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IFKFHHFF_01429 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IFKFHHFF_01430 2.9e-137 gltS ET Belongs to the bacterial solute-binding protein 3 family
IFKFHHFF_01431 2.8e-202 arcT 2.6.1.1 E Aminotransferase
IFKFHHFF_01432 6.5e-137 ET Belongs to the bacterial solute-binding protein 3 family
IFKFHHFF_01433 1.3e-143 ET Belongs to the bacterial solute-binding protein 3 family
IFKFHHFF_01434 2.2e-84 mutT 3.6.1.55 F Nudix family
IFKFHHFF_01435 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IFKFHHFF_01436 2.9e-57 V CAAX protease self-immunity
IFKFHHFF_01437 7.6e-32 S CAAX amino terminal protease family protein
IFKFHHFF_01438 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
IFKFHHFF_01439 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
IFKFHHFF_01440 1.1e-16 XK27_00735
IFKFHHFF_01441 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IFKFHHFF_01443 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IFKFHHFF_01446 2.3e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
IFKFHHFF_01447 7.7e-52 V Psort location Cytoplasmic, score
IFKFHHFF_01448 2.3e-156 K sequence-specific DNA binding
IFKFHHFF_01449 8.9e-253 C Arylsulfatase regulator (Fe-S oxidoreductase)
IFKFHHFF_01450 9.4e-289 V (ABC) transporter
IFKFHHFF_01451 9.6e-10
IFKFHHFF_01452 1.9e-43 S Domain of unknown function (DUF4299)
IFKFHHFF_01453 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
IFKFHHFF_01455 5.9e-155 EG Permeases of the drug metabolite transporter (DMT) superfamily
IFKFHHFF_01457 2e-115 serB 3.1.3.3 E phosphoserine phosphatase
IFKFHHFF_01458 2.1e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IFKFHHFF_01459 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IFKFHHFF_01460 2.6e-109 3.1.3.18 S IA, variant 1
IFKFHHFF_01461 1.6e-118 lrgB M effector of murein hydrolase
IFKFHHFF_01462 2.2e-58 lrgA S Effector of murein hydrolase LrgA
IFKFHHFF_01464 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
IFKFHHFF_01465 1.4e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IFKFHHFF_01466 1.3e-104 wecD M Acetyltransferase (GNAT) domain
IFKFHHFF_01467 6.1e-210 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IFKFHHFF_01468 3.4e-118 GK ROK family
IFKFHHFF_01469 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
IFKFHHFF_01470 2.2e-77 XK27_08050 O stress-induced mitochondrial fusion
IFKFHHFF_01471 3.1e-23 XK27_08050 O HflC and HflK could regulate a protease
IFKFHHFF_01473 2.3e-206 potD P spermidine putrescine ABC transporter
IFKFHHFF_01474 8.6e-134 potC P ABC-type spermidine putrescine transport system, permease component II
IFKFHHFF_01475 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
IFKFHHFF_01476 7.3e-214 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IFKFHHFF_01477 4.6e-171 murB 1.3.1.98 M cell wall formation
IFKFHHFF_01478 5e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IFKFHHFF_01479 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IFKFHHFF_01480 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
IFKFHHFF_01481 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IFKFHHFF_01482 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
IFKFHHFF_01483 0.0 ydaO E amino acid
IFKFHHFF_01484 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IFKFHHFF_01485 4.1e-37 ylqC L Belongs to the UPF0109 family
IFKFHHFF_01486 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IFKFHHFF_01487 6.9e-172 tehB 2.1.1.265 Q Methyltransferase
IFKFHHFF_01488 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
IFKFHHFF_01489 2.8e-74 S QueT transporter
IFKFHHFF_01490 5.2e-121 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
IFKFHHFF_01491 4.3e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IFKFHHFF_01492 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IFKFHHFF_01493 1.3e-85 ccl S cog cog4708
IFKFHHFF_01494 7.4e-164 rbn E Belongs to the UPF0761 family
IFKFHHFF_01495 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IFKFHHFF_01496 1.7e-232 ytoI K transcriptional regulator containing CBS domains
IFKFHHFF_01497 3.7e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
IFKFHHFF_01498 3.1e-234 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IFKFHHFF_01499 0.0 comEC S Competence protein ComEC
IFKFHHFF_01500 4e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IFKFHHFF_01501 1.3e-142 plsC 2.3.1.51 I Acyltransferase
IFKFHHFF_01502 1.4e-82 nodB3 G polysaccharide deacetylase
IFKFHHFF_01503 4.1e-49 nodB3 G polysaccharide deacetylase
IFKFHHFF_01504 9.3e-141 yabB 2.1.1.223 L Methyltransferase
IFKFHHFF_01505 1e-41 yazA L endonuclease containing a URI domain
IFKFHHFF_01506 1.9e-257 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IFKFHHFF_01507 2.3e-154 corA P CorA-like protein
IFKFHHFF_01508 2.5e-62 yjqA S Bacterial PH domain
IFKFHHFF_01509 7.8e-100 thiT S Thiamine transporter
IFKFHHFF_01510 9.5e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IFKFHHFF_01511 3.2e-201 yjbB G Permeases of the major facilitator superfamily
IFKFHHFF_01512 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IFKFHHFF_01513 1.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
IFKFHHFF_01514 3.6e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IFKFHHFF_01517 8.8e-156 cjaA ET ABC transporter substrate-binding protein
IFKFHHFF_01518 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
IFKFHHFF_01519 7.8e-107 P ABC transporter (Permease
IFKFHHFF_01520 6e-115 papP P ABC transporter (Permease
IFKFHHFF_01521 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IFKFHHFF_01522 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
IFKFHHFF_01523 0.0 copA 3.6.3.54 P P-type ATPase
IFKFHHFF_01524 3.2e-74 copY K negative regulation of transcription, DNA-templated
IFKFHHFF_01525 4.1e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IFKFHHFF_01526 1.3e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IFKFHHFF_01527 5e-102 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
IFKFHHFF_01528 2.9e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IFKFHHFF_01529 1e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IFKFHHFF_01530 2.1e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
IFKFHHFF_01531 2.5e-258 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IFKFHHFF_01532 1.3e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
IFKFHHFF_01533 3.2e-56
IFKFHHFF_01534 0.0 ctpE P E1-E2 ATPase
IFKFHHFF_01535 6.1e-27
IFKFHHFF_01536 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IFKFHHFF_01537 5.1e-47 L transposase activity
IFKFHHFF_01538 2.6e-132 K transcriptional regulator, MerR family
IFKFHHFF_01539 3.4e-106 dnaQ 2.7.7.7 L DNA polymerase III
IFKFHHFF_01540 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
IFKFHHFF_01541 7.4e-64 XK27_02560 S cog cog2151
IFKFHHFF_01542 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IFKFHHFF_01543 7.7e-227 ytfP S Flavoprotein
IFKFHHFF_01545 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IFKFHHFF_01546 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
IFKFHHFF_01547 1.2e-183 ecsB U ABC transporter
IFKFHHFF_01548 2.3e-133 ecsA V abc transporter atp-binding protein
IFKFHHFF_01549 6e-73 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IFKFHHFF_01550 2.8e-11
IFKFHHFF_01551 3.2e-110
IFKFHHFF_01552 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
IFKFHHFF_01553 6.9e-206 ylbM S Belongs to the UPF0348 family
IFKFHHFF_01554 2e-140 yqeM Q Methyltransferase domain protein
IFKFHHFF_01555 3.5e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IFKFHHFF_01556 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IFKFHHFF_01557 4.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IFKFHHFF_01558 3.5e-49 yhbY J RNA-binding protein
IFKFHHFF_01559 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IFKFHHFF_01560 1.8e-98 yqeG S hydrolase of the HAD superfamily
IFKFHHFF_01561 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IFKFHHFF_01562 1.4e-65
IFKFHHFF_01563 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IFKFHHFF_01564 1.8e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IFKFHHFF_01565 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IFKFHHFF_01566 4.4e-25 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
IFKFHHFF_01567 7.4e-32 M lipopolysaccharide 3-alpha-galactosyltransferase activity
IFKFHHFF_01568 1.6e-57 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFKFHHFF_01569 6.5e-181 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IFKFHHFF_01570 1.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IFKFHHFF_01571 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
IFKFHHFF_01572 4.7e-102 pncA Q isochorismatase
IFKFHHFF_01573 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IFKFHHFF_01574 6.2e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
IFKFHHFF_01575 2.4e-75 XK27_03180 T universal stress protein
IFKFHHFF_01578 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IFKFHHFF_01579 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
IFKFHHFF_01580 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
IFKFHHFF_01581 0.0 yjcE P NhaP-type Na H and K H antiporters
IFKFHHFF_01583 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
IFKFHHFF_01584 1.3e-184 yhcC S radical SAM protein
IFKFHHFF_01585 2.2e-196 ylbL T Belongs to the peptidase S16 family
IFKFHHFF_01586 2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IFKFHHFF_01587 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
IFKFHHFF_01588 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IFKFHHFF_01589 2.8e-08 S Protein of unknown function (DUF4059)
IFKFHHFF_01590 3.4e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
IFKFHHFF_01591 1.1e-173 yxeN P ABC transporter (Permease
IFKFHHFF_01592 8.8e-153 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IFKFHHFF_01594 1.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IFKFHHFF_01595 0.0 pflB 2.3.1.54 C formate acetyltransferase'
IFKFHHFF_01596 1.2e-148 cah 4.2.1.1 P carbonic anhydrase
IFKFHHFF_01597 2.7e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IFKFHHFF_01598 5e-47 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
IFKFHHFF_01599 1.3e-47 D nuclear chromosome segregation
IFKFHHFF_01600 1.9e-35 D nuclear chromosome segregation
IFKFHHFF_01601 3.4e-82 L DNA integration
IFKFHHFF_01602 1.3e-125 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
IFKFHHFF_01603 8.9e-128 ybbM S transport system, permease component
IFKFHHFF_01604 9.4e-118 ybbL S abc transporter atp-binding protein
IFKFHHFF_01605 2.9e-29
IFKFHHFF_01606 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
IFKFHHFF_01607 1.6e-140 cppA E CppA N-terminal
IFKFHHFF_01608 2.7e-29 V CAAX protease self-immunity
IFKFHHFF_01609 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
IFKFHHFF_01610 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IFKFHHFF_01613 2e-46 spiA K sequence-specific DNA binding
IFKFHHFF_01614 1.2e-137 blpT
IFKFHHFF_01615 3.9e-122 L Transposase
IFKFHHFF_01616 1.2e-165 L integrase core domain
IFKFHHFF_01621 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
IFKFHHFF_01622 6.8e-133 agrA KT phosphorelay signal transduction system
IFKFHHFF_01623 3.8e-238 blpH 2.7.13.3 T protein histidine kinase activity
IFKFHHFF_01625 4.5e-158 mesE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IFKFHHFF_01626 2.7e-44 mesE M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IFKFHHFF_01627 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IFKFHHFF_01628 0.0 mdlB V abc transporter atp-binding protein
IFKFHHFF_01629 0.0 mdlA V abc transporter atp-binding protein
IFKFHHFF_01631 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
IFKFHHFF_01632 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IFKFHHFF_01633 2.3e-72 yutD J protein conserved in bacteria
IFKFHHFF_01634 1.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IFKFHHFF_01636 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IFKFHHFF_01637 3.7e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IFKFHHFF_01638 0.0 ftsI 3.4.16.4 M penicillin-binding protein
IFKFHHFF_01639 5.6e-47 ftsL D cell division protein FtsL
IFKFHHFF_01640 3e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IFKFHHFF_01641 3.3e-162
IFKFHHFF_01642 6.3e-31 yhaI J Protein of unknown function (DUF805)
IFKFHHFF_01643 3.5e-10 D nuclear chromosome segregation
IFKFHHFF_01644 6.9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IFKFHHFF_01645 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IFKFHHFF_01646 1.4e-287 XK27_00765
IFKFHHFF_01647 1.1e-89 ecsA_2 V abc transporter atp-binding protein
IFKFHHFF_01648 2e-45 ecsA_2 V ATPase activity
IFKFHHFF_01649 1.5e-104 S Protein of unknown function (DUF554)
IFKFHHFF_01650 1.6e-11 S Protein of unknown function (DUF554)
IFKFHHFF_01651 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IFKFHHFF_01652 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IFKFHHFF_01653 2.6e-66 liaI S membrane
IFKFHHFF_01654 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
IFKFHHFF_01655 3.6e-66 KT response to antibiotic
IFKFHHFF_01656 9.1e-18 KT response to antibiotic
IFKFHHFF_01657 1.6e-80 yebC M Membrane
IFKFHHFF_01658 8.5e-18 yebC M Membrane
IFKFHHFF_01659 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
IFKFHHFF_01660 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IFKFHHFF_01661 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IFKFHHFF_01662 6.2e-186 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IFKFHHFF_01663 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IFKFHHFF_01664 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IFKFHHFF_01665 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IFKFHHFF_01666 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IFKFHHFF_01668 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
IFKFHHFF_01669 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
IFKFHHFF_01670 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
IFKFHHFF_01671 4.1e-291 scrB 3.2.1.26 GH32 G invertase
IFKFHHFF_01672 5.1e-34 scrR K purine nucleotide biosynthetic process
IFKFHHFF_01673 4.3e-115 scrR K purine nucleotide biosynthetic process
IFKFHHFF_01674 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IFKFHHFF_01675 3.4e-62 yqhY S protein conserved in bacteria
IFKFHHFF_01676 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IFKFHHFF_01677 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
IFKFHHFF_01678 3.8e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
IFKFHHFF_01680 1e-09 V 'abc transporter, ATP-binding protein
IFKFHHFF_01681 3.2e-20 V 'abc transporter, ATP-binding protein
IFKFHHFF_01682 2.5e-36 V ATPase activity
IFKFHHFF_01685 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IFKFHHFF_01686 2e-169 corA P COG0598 Mg2 and Co2 transporters
IFKFHHFF_01687 4.1e-124 XK27_01040 S Pfam PF06570
IFKFHHFF_01689 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IFKFHHFF_01690 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IFKFHHFF_01691 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
IFKFHHFF_01693 2.8e-28 XK27_05745
IFKFHHFF_01694 4.2e-230 mutY L A G-specific adenine glycosylase
IFKFHHFF_01698 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IFKFHHFF_01699 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IFKFHHFF_01700 1.3e-93 cvpA S toxin biosynthetic process
IFKFHHFF_01701 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IFKFHHFF_01702 3.6e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IFKFHHFF_01703 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IFKFHHFF_01704 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IFKFHHFF_01705 8.8e-48 azlD E branched-chain amino acid
IFKFHHFF_01706 3.8e-117 azlC E AzlC protein
IFKFHHFF_01707 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IFKFHHFF_01708 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IFKFHHFF_01709 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
IFKFHHFF_01710 2.5e-33 ykzG S Belongs to the UPF0356 family
IFKFHHFF_01711 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IFKFHHFF_01712 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
IFKFHHFF_01713 8.5e-63 glnR K Transcriptional regulator
IFKFHHFF_01714 1.3e-87 S Fusaric acid resistance protein-like
IFKFHHFF_01715 3e-13
IFKFHHFF_01716 2.6e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IFKFHHFF_01717 5.5e-42 L Transposase
IFKFHHFF_01718 9.4e-46 L transposase activity
IFKFHHFF_01719 5.7e-23 L Transposase
IFKFHHFF_01720 3.1e-56 L transposition
IFKFHHFF_01721 4.5e-88 L Integrase core domain protein
IFKFHHFF_01722 2.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IFKFHHFF_01723 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IFKFHHFF_01724 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IFKFHHFF_01725 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IFKFHHFF_01726 9.4e-183 L Transposase and inactivated derivatives IS30 family
IFKFHHFF_01727 8.2e-143 purR 2.4.2.22, 2.4.2.7 F operon repressor
IFKFHHFF_01728 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
IFKFHHFF_01729 6.9e-173 rmuC S RmuC domain protein
IFKFHHFF_01730 2.4e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
IFKFHHFF_01731 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IFKFHHFF_01732 1.2e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IFKFHHFF_01734 6.2e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IFKFHHFF_01735 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IFKFHHFF_01736 1.4e-144 tatD L Hydrolase, tatd
IFKFHHFF_01737 1.5e-74 yccU S CoA-binding protein
IFKFHHFF_01738 4.8e-51 trxA O Belongs to the thioredoxin family
IFKFHHFF_01739 7.8e-143 S Macro domain protein
IFKFHHFF_01740 2.7e-09 L thioesterase
IFKFHHFF_01741 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
IFKFHHFF_01744 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IFKFHHFF_01745 1.6e-87 L Transposase
IFKFHHFF_01746 1e-13 rpmH J Ribosomal protein L34
IFKFHHFF_01747 6.9e-187 jag S RNA-binding protein
IFKFHHFF_01748 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IFKFHHFF_01749 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IFKFHHFF_01750 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
IFKFHHFF_01751 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IFKFHHFF_01752 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IFKFHHFF_01753 1.4e-81 amiA E transmembrane transport
IFKFHHFF_01754 4.9e-75 amiA E transmembrane transport
IFKFHHFF_01755 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IFKFHHFF_01756 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IFKFHHFF_01757 9.2e-51 S Protein of unknown function (DUF3397)
IFKFHHFF_01758 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
IFKFHHFF_01759 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
IFKFHHFF_01760 8.1e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
IFKFHHFF_01761 4.8e-227 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IFKFHHFF_01762 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IFKFHHFF_01763 4.1e-65 XK27_09620 S FMN reductase (NADPH) activity
IFKFHHFF_01764 8.3e-34 XK27_09620 S FMN reductase (NADPH) activity
IFKFHHFF_01765 6.6e-34 XK27_09615 S FMN reductase (NADPH) activity
IFKFHHFF_01766 1.9e-132 XK27_09615 S PAS domain
IFKFHHFF_01767 2.9e-63 fnt P Formate nitrite transporter
IFKFHHFF_01768 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
IFKFHHFF_01769 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IFKFHHFF_01770 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IFKFHHFF_01771 1.2e-165 L integrase core domain
IFKFHHFF_01772 1.5e-121 L Transposase
IFKFHHFF_01773 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IFKFHHFF_01774 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IFKFHHFF_01775 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IFKFHHFF_01776 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IFKFHHFF_01777 9.1e-65 S glycolate biosynthetic process
IFKFHHFF_01778 4e-65 S phosphatase activity
IFKFHHFF_01779 5.7e-160 rrmA 2.1.1.187 Q methyltransferase
IFKFHHFF_01782 9.2e-92 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IFKFHHFF_01783 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IFKFHHFF_01784 6.4e-37 yeeD O sulfur carrier activity
IFKFHHFF_01785 9.2e-192 yeeE S Sulphur transport
IFKFHHFF_01786 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IFKFHHFF_01787 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IFKFHHFF_01788 1.8e-09 S Domain of unknown function (DUF4651)
IFKFHHFF_01789 2.6e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IFKFHHFF_01790 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IFKFHHFF_01791 5.4e-113 S CAAX amino terminal protease family protein
IFKFHHFF_01793 7.6e-68 V CAAX protease self-immunity
IFKFHHFF_01794 8.8e-27 lanR K sequence-specific DNA binding
IFKFHHFF_01795 2.6e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IFKFHHFF_01796 5.9e-177 ytxK 2.1.1.72 L DNA methylase
IFKFHHFF_01797 8.9e-13 comGF U Putative Competence protein ComGF
IFKFHHFF_01798 4e-72 comGF U Competence protein ComGF
IFKFHHFF_01799 1.4e-15 NU Type II secretory pathway pseudopilin
IFKFHHFF_01800 1.8e-57 cglD NU Competence protein
IFKFHHFF_01801 1.5e-42 comGC U Required for transformation and DNA binding
IFKFHHFF_01802 9.2e-153 cglB NU type II secretion system
IFKFHHFF_01803 4.5e-177 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IFKFHHFF_01804 1e-68 S cog cog4699
IFKFHHFF_01805 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFKFHHFF_01806 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFKFHHFF_01807 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IFKFHHFF_01808 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IFKFHHFF_01809 1.2e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IFKFHHFF_01810 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
IFKFHHFF_01811 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
IFKFHHFF_01812 6.1e-282 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IFKFHHFF_01813 3.3e-11 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IFKFHHFF_01814 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
IFKFHHFF_01815 1.4e-57 asp S cog cog1302
IFKFHHFF_01816 8.4e-227 norM V Mate efflux family protein
IFKFHHFF_01817 4.9e-279 thrC 4.2.3.1 E Threonine synthase
IFKFHHFF_01818 8.3e-63 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IFKFHHFF_01819 7.2e-36 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
IFKFHHFF_01820 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IFKFHHFF_01821 1.1e-103 1.1.1.1, 1.1.99.1, 1.2.1.10, 1.2.1.18, 1.2.1.27, 1.2.1.3 C Dehydrogenase
IFKFHHFF_01822 3.2e-31 C belongs to the aldehyde dehydrogenase family
IFKFHHFF_01823 5.1e-66 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
IFKFHHFF_01824 0.0 pepO 3.4.24.71 O Peptidase family M13
IFKFHHFF_01825 2.3e-120 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IFKFHHFF_01826 7e-67 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IFKFHHFF_01827 2e-56 treB 2.7.1.201 G PTS System
IFKFHHFF_01828 5.8e-21 treR K DNA-binding transcription factor activity
IFKFHHFF_01829 7.8e-88 treR K trehalose operon
IFKFHHFF_01830 3.3e-95 ywlG S Belongs to the UPF0340 family
IFKFHHFF_01833 2.7e-13 L PFAM Integrase, catalytic core
IFKFHHFF_01834 5.1e-78 L PFAM Integrase, catalytic core
IFKFHHFF_01835 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
IFKFHHFF_01837 2.1e-111 6.3.2.2 H ergothioneine biosynthetic process
IFKFHHFF_01838 1.1e-16 6.3.2.2 H gamma-glutamylcysteine synthetase
IFKFHHFF_01839 2.5e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
IFKFHHFF_01840 2.7e-13 L PFAM Integrase, catalytic core
IFKFHHFF_01841 5.1e-78 L PFAM Integrase, catalytic core
IFKFHHFF_01842 3.3e-62 rplQ J ribosomal protein l17
IFKFHHFF_01843 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IFKFHHFF_01844 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IFKFHHFF_01845 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IFKFHHFF_01846 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IFKFHHFF_01847 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IFKFHHFF_01848 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IFKFHHFF_01849 1.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IFKFHHFF_01850 7.4e-58 rplO J binds to the 23S rRNA
IFKFHHFF_01851 2.5e-23 rpmD J ribosomal protein l30
IFKFHHFF_01852 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IFKFHHFF_01853 1.1e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IFKFHHFF_01854 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IFKFHHFF_01855 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IFKFHHFF_01856 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IFKFHHFF_01857 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IFKFHHFF_01858 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IFKFHHFF_01859 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IFKFHHFF_01860 2e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IFKFHHFF_01861 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
IFKFHHFF_01862 3.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IFKFHHFF_01863 3.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IFKFHHFF_01864 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IFKFHHFF_01865 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IFKFHHFF_01866 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IFKFHHFF_01867 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IFKFHHFF_01868 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
IFKFHHFF_01869 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IFKFHHFF_01870 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
IFKFHHFF_01871 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IFKFHHFF_01872 0.0 XK27_09800 I Acyltransferase
IFKFHHFF_01873 1.7e-35 XK27_09805 S MORN repeat protein
IFKFHHFF_01874 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IFKFHHFF_01875 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IFKFHHFF_01876 8.9e-95 adk 2.7.4.3 F topology modulation protein
IFKFHHFF_01878 1.4e-223 L Transposase
IFKFHHFF_01880 3.4e-155 Z012_04635 K sequence-specific DNA binding
IFKFHHFF_01881 0.0 KLT serine threonine protein kinase
IFKFHHFF_01882 2.1e-280 V ABC transporter
IFKFHHFF_01883 3.3e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IFKFHHFF_01884 1.3e-128 Z012_04635 K sequence-specific DNA binding
IFKFHHFF_01886 3.6e-232 C Radical SAM
IFKFHHFF_01887 3.9e-287 V ABC transporter transmembrane region
IFKFHHFF_01888 1e-155 L Replication initiation factor
IFKFHHFF_01889 1.9e-18 S Domain of unknown function (DUF3173)
IFKFHHFF_01890 3.5e-216 int L Belongs to the 'phage' integrase family
IFKFHHFF_01892 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
IFKFHHFF_01893 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IFKFHHFF_01894 2.2e-44 yrzL S Belongs to the UPF0297 family
IFKFHHFF_01895 9.5e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IFKFHHFF_01896 4.2e-44 yrzB S Belongs to the UPF0473 family
IFKFHHFF_01897 3.5e-302 ccs S the current gene model (or a revised gene model) may contain a frame shift
IFKFHHFF_01898 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IFKFHHFF_01899 7.5e-14
IFKFHHFF_01900 3.4e-91 XK27_10930 K acetyltransferase
IFKFHHFF_01901 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IFKFHHFF_01902 2.2e-145 yaaA S Belongs to the UPF0246 family
IFKFHHFF_01903 3.4e-169 XK27_01785 S cog cog1284
IFKFHHFF_01904 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IFKFHHFF_01906 1.2e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
IFKFHHFF_01907 4.3e-130 metE 2.1.1.14 E Methionine synthase
IFKFHHFF_01908 1.4e-36 yxjG 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IFKFHHFF_01909 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IFKFHHFF_01910 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IFKFHHFF_01913 4.8e-51 yegS 2.7.1.107 I lipid kinase activity
IFKFHHFF_01914 8.5e-97 S Hydrophobic domain protein
IFKFHHFF_01916 7.4e-28 S Membrane
IFKFHHFF_01917 1.4e-101
IFKFHHFF_01918 1.8e-23 S Small integral membrane protein
IFKFHHFF_01919 9.4e-183 L Transposase and inactivated derivatives IS30 family
IFKFHHFF_01920 6.6e-86 M Protein conserved in bacteria
IFKFHHFF_01921 2.8e-12 K CsbD-like
IFKFHHFF_01922 2.8e-102 nudL L hydrolase
IFKFHHFF_01923 3.4e-13 nudL L hydrolase
IFKFHHFF_01924 4e-19 K negative regulation of transcription, DNA-templated
IFKFHHFF_01925 4.4e-24 K negative regulation of transcription, DNA-templated
IFKFHHFF_01927 8e-109 S Putative adhesin
IFKFHHFF_01928 1.4e-125 XK27_06930 V domain protein
IFKFHHFF_01929 2.9e-41 XK27_06930 Q domain protein
IFKFHHFF_01930 6.4e-96 XK27_06935 K transcriptional regulator
IFKFHHFF_01931 4.8e-55 ypaA S membrane
IFKFHHFF_01932 2.7e-08
IFKFHHFF_01933 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IFKFHHFF_01934 8.2e-48 veg S Biofilm formation stimulator VEG
IFKFHHFF_01935 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IFKFHHFF_01936 6.7e-70 rplI J binds to the 23S rRNA
IFKFHHFF_01937 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IFKFHHFF_01938 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IFKFHHFF_01939 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IFKFHHFF_01940 0.0 S Bacterial membrane protein, YfhO
IFKFHHFF_01941 2e-93 isaA GH23 M Immunodominant staphylococcal antigen A
IFKFHHFF_01942 3.1e-93 lytE M LysM domain protein
IFKFHHFF_01943 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFKFHHFF_01944 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFKFHHFF_01945 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IFKFHHFF_01946 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IFKFHHFF_01947 1.7e-138 ymfM S sequence-specific DNA binding
IFKFHHFF_01948 3.1e-242 ymfH S Peptidase M16
IFKFHHFF_01949 1.4e-234 ymfF S Peptidase M16
IFKFHHFF_01950 1.6e-45 yaaA S S4 domain protein YaaA
IFKFHHFF_01951 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IFKFHHFF_01952 1.1e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IFKFHHFF_01953 9.4e-183 L Transposase and inactivated derivatives IS30 family
IFKFHHFF_01954 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IFKFHHFF_01955 3.9e-54 yvjA S membrane
IFKFHHFF_01956 8.3e-70 yvjA S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IFKFHHFF_01957 6.7e-306 ybiT S abc transporter atp-binding protein
IFKFHHFF_01958 0.0 XK27_10405 S Bacterial membrane protein YfhO
IFKFHHFF_01962 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
IFKFHHFF_01963 8.6e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IFKFHHFF_01964 1.1e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IFKFHHFF_01965 7.7e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)