ORF_ID e_value Gene_name EC_number CAZy COGs Description
KGFAGBON_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KGFAGBON_00002 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KGFAGBON_00003 9.3e-239 L Transposase
KGFAGBON_00004 1.1e-29 yyzM S Protein conserved in bacteria
KGFAGBON_00005 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KGFAGBON_00006 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KGFAGBON_00007 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KGFAGBON_00008 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KGFAGBON_00009 2.7e-61 divIC D Septum formation initiator
KGFAGBON_00011 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KGFAGBON_00012 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KGFAGBON_00013 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KGFAGBON_00014 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KGFAGBON_00015 2.4e-164 L Transposase
KGFAGBON_00016 1.1e-92 L Transposase
KGFAGBON_00017 1.6e-55 L transposition
KGFAGBON_00018 2.6e-88 L Integrase core domain protein
KGFAGBON_00031 5.3e-11
KGFAGBON_00037 1.3e-140 mreC M Involved in formation and maintenance of cell shape
KGFAGBON_00038 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KGFAGBON_00039 8.9e-102 usp 3.5.1.28 CBM50 S CHAP domain
KGFAGBON_00040 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KGFAGBON_00041 2.5e-26
KGFAGBON_00042 5.9e-219 araT 2.6.1.1 E Aminotransferase
KGFAGBON_00043 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
KGFAGBON_00044 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KGFAGBON_00045 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KGFAGBON_00046 5.2e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KGFAGBON_00047 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KGFAGBON_00048 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KGFAGBON_00049 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KGFAGBON_00050 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KGFAGBON_00051 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KGFAGBON_00052 1e-90 L transposase activity
KGFAGBON_00053 3.5e-50 L transposition
KGFAGBON_00054 2e-32 L Integrase core domain protein
KGFAGBON_00055 2.3e-161 S CHAP domain
KGFAGBON_00056 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
KGFAGBON_00057 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KGFAGBON_00058 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KGFAGBON_00059 9.2e-141 1.1.1.169 H Ketopantoate reductase
KGFAGBON_00060 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KGFAGBON_00061 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KGFAGBON_00062 8.2e-70 argR K Regulates arginine biosynthesis genes
KGFAGBON_00063 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KGFAGBON_00064 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KGFAGBON_00065 1.9e-80 S Protein of unknown function (DUF3021)
KGFAGBON_00066 6.5e-63 KT phosphorelay signal transduction system
KGFAGBON_00068 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KGFAGBON_00070 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KGFAGBON_00071 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KGFAGBON_00072 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
KGFAGBON_00073 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KGFAGBON_00074 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KGFAGBON_00080 2.6e-10
KGFAGBON_00083 1.9e-07
KGFAGBON_00088 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KGFAGBON_00089 2.3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KGFAGBON_00090 1.9e-36 XK27_02060 S Transglycosylase associated protein
KGFAGBON_00091 2.6e-55 badR K DNA-binding transcription factor activity
KGFAGBON_00092 3.5e-97 S reductase
KGFAGBON_00093 6.9e-89 L Integrase core domain protein
KGFAGBON_00094 6.4e-41 L transposition
KGFAGBON_00095 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
KGFAGBON_00096 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KGFAGBON_00099 1.6e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KGFAGBON_00100 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KGFAGBON_00101 5.5e-83 S Putative small multi-drug export protein
KGFAGBON_00102 1.8e-75 ctsR K Belongs to the CtsR family
KGFAGBON_00103 0.0 clpC O Belongs to the ClpA ClpB family
KGFAGBON_00104 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KGFAGBON_00105 1.7e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KGFAGBON_00106 6.7e-122 L Helix-turn-helix domain
KGFAGBON_00107 1.2e-165 L integrase core domain
KGFAGBON_00108 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KGFAGBON_00109 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KGFAGBON_00110 6.9e-144 S SseB protein N-terminal domain
KGFAGBON_00111 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
KGFAGBON_00112 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KGFAGBON_00113 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KGFAGBON_00116 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KGFAGBON_00117 3.5e-91 yacP S RNA-binding protein containing a PIN domain
KGFAGBON_00118 3.4e-155 degV S DegV family
KGFAGBON_00120 1.8e-31 K helix-turn-helix
KGFAGBON_00121 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KGFAGBON_00122 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KGFAGBON_00123 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KGFAGBON_00124 1.5e-35 K sequence-specific DNA binding
KGFAGBON_00126 0.0
KGFAGBON_00127 1.2e-88 L Transposase
KGFAGBON_00128 5.9e-64 L Transposase
KGFAGBON_00129 4.7e-56 EGP Major facilitator Superfamily
KGFAGBON_00130 7.7e-112 EGP Major facilitator Superfamily
KGFAGBON_00131 5.9e-24 3.6.4.12
KGFAGBON_00132 1.4e-92 3.6.4.12 K Divergent AAA domain protein
KGFAGBON_00133 1.1e-236 L Helix-turn-helix domain of transposase family ISL3
KGFAGBON_00134 6.2e-128 tnp L DDE domain
KGFAGBON_00135 1.9e-57 L Transposase
KGFAGBON_00137 0.0 ddpA E ABC transporter substrate-binding protein
KGFAGBON_00138 2.8e-188 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFAGBON_00139 1.8e-141 dppC P N-terminal TM domain of oligopeptide transport permease C
KGFAGBON_00140 0.0 P Belongs to the ABC transporter superfamily
KGFAGBON_00141 3e-13 mesE M Transport protein ComB
KGFAGBON_00142 2.4e-178 L transposase, IS4 family
KGFAGBON_00143 2.1e-128 tnp L DDE domain
KGFAGBON_00144 1.9e-225 nodC 2.4.1.212 GT2 M Chitin synthase
KGFAGBON_00145 2.4e-214 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KGFAGBON_00146 1.8e-237 L Transposase
KGFAGBON_00147 5.7e-91 tnp L Transposase
KGFAGBON_00148 1.2e-42 capA M Bacterial capsule synthesis protein PGA_cap
KGFAGBON_00149 4.3e-109 capA M Bacterial capsule synthesis protein
KGFAGBON_00150 1.5e-55 capA M Bacterial capsule synthesis protein
KGFAGBON_00151 3.6e-39 gcvR T UPF0237 protein
KGFAGBON_00152 1.7e-243 XK27_08635 S UPF0210 protein
KGFAGBON_00153 2.4e-135 ais G Phosphoglycerate mutase
KGFAGBON_00154 2.1e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KGFAGBON_00155 1.3e-102 acmA 3.2.1.17 NU amidase activity
KGFAGBON_00156 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KGFAGBON_00157 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KGFAGBON_00158 7.5e-298 dnaK O Heat shock 70 kDa protein
KGFAGBON_00159 3.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KGFAGBON_00160 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KGFAGBON_00161 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KGFAGBON_00162 3.8e-31 hmpT S membrane
KGFAGBON_00175 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KGFAGBON_00176 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KGFAGBON_00177 1e-84
KGFAGBON_00178 1.6e-77 sigH K DNA-templated transcription, initiation
KGFAGBON_00179 3e-148 ykuT M mechanosensitive ion channel
KGFAGBON_00180 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KGFAGBON_00181 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KGFAGBON_00182 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KGFAGBON_00183 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
KGFAGBON_00184 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KGFAGBON_00185 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
KGFAGBON_00186 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KGFAGBON_00187 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KGFAGBON_00188 6.3e-96 nrdI F Belongs to the NrdI family
KGFAGBON_00189 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KGFAGBON_00190 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KGFAGBON_00191 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KGFAGBON_00192 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KGFAGBON_00193 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KGFAGBON_00194 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KGFAGBON_00195 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KGFAGBON_00196 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KGFAGBON_00197 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KGFAGBON_00198 6.5e-202 yhjX P Major Facilitator
KGFAGBON_00199 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KGFAGBON_00200 5e-94 V VanZ like family
KGFAGBON_00203 1e-123 glnQ E abc transporter atp-binding protein
KGFAGBON_00204 1.8e-276 glnP P ABC transporter
KGFAGBON_00205 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KGFAGBON_00206 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KGFAGBON_00207 4.9e-186 tagO 2.7.8.33, 2.7.8.35 M transferase
KGFAGBON_00208 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KGFAGBON_00209 6.3e-235 sufD O assembly protein SufD
KGFAGBON_00210 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KGFAGBON_00211 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
KGFAGBON_00212 3.5e-274 sufB O assembly protein SufB
KGFAGBON_00213 2.4e-19 oppA E ABC transporter substrate-binding protein
KGFAGBON_00214 5.4e-99 oppA E ABC transporter substrate-binding protein
KGFAGBON_00215 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFAGBON_00216 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFAGBON_00217 5.4e-46 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFAGBON_00218 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KGFAGBON_00219 8e-28 oppD P Belongs to the ABC transporter superfamily
KGFAGBON_00220 2.5e-32 oppD P Belongs to the ABC transporter superfamily
KGFAGBON_00221 4.8e-67 oppD P Belongs to the ABC transporter superfamily
KGFAGBON_00222 1.3e-44 oppD P Belongs to the ABC transporter superfamily
KGFAGBON_00223 9e-170 oppF P Belongs to the ABC transporter superfamily
KGFAGBON_00226 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KGFAGBON_00227 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KGFAGBON_00228 1.9e-209 EGP Major facilitator Superfamily
KGFAGBON_00229 2.4e-72 adcR K transcriptional
KGFAGBON_00230 2.2e-136 adcC P ABC transporter, ATP-binding protein
KGFAGBON_00231 5.4e-131 adcB P ABC transporter (Permease
KGFAGBON_00232 4.8e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KGFAGBON_00233 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
KGFAGBON_00234 6e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
KGFAGBON_00235 1.7e-82 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KGFAGBON_00236 1e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
KGFAGBON_00237 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
KGFAGBON_00238 1.9e-127 yeeN K transcriptional regulatory protein
KGFAGBON_00239 9.8e-50 yajC U protein transport
KGFAGBON_00240 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KGFAGBON_00241 1.3e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KGFAGBON_00242 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KGFAGBON_00243 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KGFAGBON_00244 1.1e-298 WQ51_06230 S ABC transporter
KGFAGBON_00245 5.2e-142 cmpC S abc transporter atp-binding protein
KGFAGBON_00246 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KGFAGBON_00247 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KGFAGBON_00248 4.4e-37 L Transposase
KGFAGBON_00249 6.4e-18 L transposase activity
KGFAGBON_00250 1.5e-30 L transposition
KGFAGBON_00253 4.7e-43
KGFAGBON_00254 6.8e-56 S TM2 domain
KGFAGBON_00255 7.3e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KGFAGBON_00256 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KGFAGBON_00257 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KGFAGBON_00258 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
KGFAGBON_00259 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KGFAGBON_00260 1.2e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KGFAGBON_00261 6e-55 cof Q phosphatase activity
KGFAGBON_00262 4e-34 cof Q phosphatase activity
KGFAGBON_00263 2.8e-76 glcR K transcriptional regulator (DeoR family)
KGFAGBON_00264 3.9e-21 glcR K transcriptional regulator (DeoR family)
KGFAGBON_00265 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KGFAGBON_00266 3.8e-40 K transcriptional
KGFAGBON_00268 2.6e-76 S thiolester hydrolase activity
KGFAGBON_00269 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
KGFAGBON_00270 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KGFAGBON_00271 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KGFAGBON_00272 1.9e-77 yhaI L Membrane
KGFAGBON_00273 4.6e-260 pepC 3.4.22.40 E aminopeptidase
KGFAGBON_00274 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KGFAGBON_00275 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KGFAGBON_00276 3.1e-95 ypsA S Belongs to the UPF0398 family
KGFAGBON_00277 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KGFAGBON_00278 7.9e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KGFAGBON_00279 1e-305 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KGFAGBON_00280 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KGFAGBON_00281 2.5e-23
KGFAGBON_00282 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KGFAGBON_00283 3.1e-20 XK27_09675 K -acetyltransferase
KGFAGBON_00284 9.3e-46 XK27_09675 K -acetyltransferase
KGFAGBON_00285 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KGFAGBON_00286 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KGFAGBON_00287 5.3e-89 L Integrase core domain protein
KGFAGBON_00288 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KGFAGBON_00289 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KGFAGBON_00290 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KGFAGBON_00291 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KGFAGBON_00292 1.5e-97 ybhL S Belongs to the BI1 family
KGFAGBON_00295 7.3e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KGFAGBON_00296 9.6e-92 K transcriptional regulator
KGFAGBON_00297 7.6e-36 yneF S UPF0154 protein
KGFAGBON_00298 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KGFAGBON_00299 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KGFAGBON_00300 3.5e-99 XK27_09740 S Phosphoesterase
KGFAGBON_00301 5.4e-86 ykuL S CBS domain
KGFAGBON_00302 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KGFAGBON_00303 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KGFAGBON_00304 2.3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KGFAGBON_00305 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KGFAGBON_00306 8.6e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KGFAGBON_00307 1.2e-258 trkH P Cation transport protein
KGFAGBON_00308 1.8e-248 trkA P Potassium transporter peripheral membrane component
KGFAGBON_00309 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KGFAGBON_00310 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KGFAGBON_00311 8.3e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KGFAGBON_00312 2.5e-161 K sequence-specific DNA binding
KGFAGBON_00313 1.6e-32 V protein secretion by the type I secretion system
KGFAGBON_00314 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KGFAGBON_00315 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KGFAGBON_00316 6.4e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KGFAGBON_00317 3.7e-22 yhaI L Membrane
KGFAGBON_00318 1.4e-54 S Domain of unknown function (DUF4173)
KGFAGBON_00319 6.8e-95 ureI S AmiS/UreI family transporter
KGFAGBON_00320 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KGFAGBON_00321 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KGFAGBON_00322 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KGFAGBON_00323 6.6e-78 ureE O enzyme active site formation
KGFAGBON_00324 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KGFAGBON_00325 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KGFAGBON_00326 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KGFAGBON_00327 2.7e-177 cbiM P PDGLE domain
KGFAGBON_00328 1.7e-137 P cobalt transport protein
KGFAGBON_00329 1.3e-131 cbiO P ABC transporter
KGFAGBON_00330 5.3e-153 ET amino acid transport
KGFAGBON_00331 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGFAGBON_00332 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
KGFAGBON_00333 3.8e-205 EGP Transmembrane secretion effector
KGFAGBON_00334 1.8e-153 ET amino acid transport
KGFAGBON_00335 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
KGFAGBON_00336 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KGFAGBON_00337 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KGFAGBON_00338 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KGFAGBON_00339 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KGFAGBON_00340 3e-98 metI P ABC transporter (Permease
KGFAGBON_00341 2.7e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KGFAGBON_00342 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KGFAGBON_00343 9.4e-95 S UPF0397 protein
KGFAGBON_00344 0.0 ykoD P abc transporter atp-binding protein
KGFAGBON_00345 1.2e-149 cbiQ P cobalt transport
KGFAGBON_00346 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KGFAGBON_00347 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
KGFAGBON_00348 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
KGFAGBON_00349 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
KGFAGBON_00350 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KGFAGBON_00351 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
KGFAGBON_00352 2.3e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFAGBON_00353 1.2e-105 T PhoQ Sensor
KGFAGBON_00354 7.8e-157 T PhoQ Sensor
KGFAGBON_00355 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KGFAGBON_00356 6.5e-218 dnaB L Replication initiation and membrane attachment
KGFAGBON_00357 5.2e-167 dnaI L Primosomal protein DnaI
KGFAGBON_00358 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KGFAGBON_00360 1.2e-34
KGFAGBON_00361 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
KGFAGBON_00362 3e-27 L Integrase core domain protein
KGFAGBON_00363 3.4e-50 L transposition
KGFAGBON_00364 5.7e-23 L Transposase
KGFAGBON_00365 7.8e-28 L transposase activity
KGFAGBON_00366 2.3e-223 L Transposase
KGFAGBON_00367 1.5e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KGFAGBON_00368 6.5e-63 manO S protein conserved in bacteria
KGFAGBON_00369 1.8e-170 manN G PTS system mannose fructose sorbose family IID component
KGFAGBON_00370 7e-118 manM G pts system
KGFAGBON_00371 1.3e-174 manL 2.7.1.191 G pts system
KGFAGBON_00372 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KGFAGBON_00373 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KGFAGBON_00374 1.9e-248 pbuO S permease
KGFAGBON_00375 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KGFAGBON_00376 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
KGFAGBON_00377 2.5e-220 brpA K Transcriptional
KGFAGBON_00378 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KGFAGBON_00379 3.1e-212 nusA K Participates in both transcription termination and antitermination
KGFAGBON_00380 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KGFAGBON_00381 1.4e-41 ylxQ J ribosomal protein
KGFAGBON_00382 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KGFAGBON_00383 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KGFAGBON_00384 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
KGFAGBON_00385 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
KGFAGBON_00386 3.2e-214 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KGFAGBON_00387 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KGFAGBON_00388 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KGFAGBON_00389 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KGFAGBON_00390 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
KGFAGBON_00391 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KGFAGBON_00392 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
KGFAGBON_00393 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KGFAGBON_00394 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KGFAGBON_00395 3.4e-74 ylbF S Belongs to the UPF0342 family
KGFAGBON_00396 7.1e-46 ylbG S UPF0298 protein
KGFAGBON_00397 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KGFAGBON_00398 1.5e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KGFAGBON_00399 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
KGFAGBON_00400 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KGFAGBON_00401 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KGFAGBON_00402 1.1e-69 acuB S IMP dehydrogenase activity
KGFAGBON_00403 3.3e-43 acuB S IMP dehydrogenase activity
KGFAGBON_00404 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KGFAGBON_00405 6.3e-111 yvyE 3.4.13.9 S YigZ family
KGFAGBON_00406 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KGFAGBON_00407 4.4e-123 comFC S Competence protein
KGFAGBON_00408 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KGFAGBON_00416 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
KGFAGBON_00417 6.4e-108 S Domain of unknown function (DUF1803)
KGFAGBON_00418 1.3e-101 ygaC J Belongs to the UPF0374 family
KGFAGBON_00419 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
KGFAGBON_00420 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KGFAGBON_00421 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
KGFAGBON_00422 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
KGFAGBON_00423 1.9e-115 S Haloacid dehalogenase-like hydrolase
KGFAGBON_00424 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KGFAGBON_00425 4e-72 marR K Transcriptional regulator, MarR family
KGFAGBON_00426 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KGFAGBON_00427 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KGFAGBON_00428 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KGFAGBON_00429 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KGFAGBON_00430 1.6e-126 IQ reductase
KGFAGBON_00431 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KGFAGBON_00432 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KGFAGBON_00433 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KGFAGBON_00434 7.5e-258 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KGFAGBON_00435 4.1e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KGFAGBON_00436 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KGFAGBON_00437 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KGFAGBON_00438 1.4e-65 tnp L Transposase
KGFAGBON_00439 1.1e-202 rny D Endoribonuclease that initiates mRNA decay
KGFAGBON_00440 1.8e-84 L Transposase
KGFAGBON_00441 5.6e-114 fruR K transcriptional
KGFAGBON_00442 2.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KGFAGBON_00443 8e-98 fruA 2.7.1.202 G phosphotransferase system
KGFAGBON_00444 5.1e-145 fruA 2.7.1.202 G phosphotransferase system
KGFAGBON_00445 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
KGFAGBON_00446 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KGFAGBON_00447 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KGFAGBON_00449 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KGFAGBON_00450 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KGFAGBON_00451 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KGFAGBON_00452 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KGFAGBON_00453 6.4e-29 2.3.1.128 K acetyltransferase
KGFAGBON_00454 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KGFAGBON_00455 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KGFAGBON_00456 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KGFAGBON_00457 2.6e-64 WQ51_03320 S cog cog4835
KGFAGBON_00458 6.4e-61 XK27_08360 S EDD domain protein, DegV family
KGFAGBON_00459 3.6e-74 XK27_08360 S EDD domain protein, DegV family
KGFAGBON_00460 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KGFAGBON_00461 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KGFAGBON_00462 0.0 yfmR S abc transporter atp-binding protein
KGFAGBON_00463 9.3e-239 L Transposase
KGFAGBON_00464 1.6e-24 U response to pH
KGFAGBON_00465 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KGFAGBON_00466 1.5e-205 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KGFAGBON_00467 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KGFAGBON_00468 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KGFAGBON_00469 1.9e-77 K DNA-binding transcription factor activity
KGFAGBON_00470 0.0 lmrA1 V abc transporter atp-binding protein
KGFAGBON_00471 0.0 lmrA2 V abc transporter atp-binding protein
KGFAGBON_00472 1.6e-44 K Acetyltransferase (GNAT) family
KGFAGBON_00473 2.9e-120 sptS 2.7.13.3 T Histidine kinase
KGFAGBON_00474 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KGFAGBON_00475 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KGFAGBON_00476 5.3e-161 cvfB S Protein conserved in bacteria
KGFAGBON_00477 7.4e-35 yozE S Belongs to the UPF0346 family
KGFAGBON_00478 4.5e-131 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
KGFAGBON_00479 2.3e-61 rlpA M LysM domain protein
KGFAGBON_00480 8e-191 phoH T phosphate starvation-inducible protein PhoH
KGFAGBON_00484 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KGFAGBON_00485 1.8e-167 K transcriptional regulator (lysR family)
KGFAGBON_00486 1.4e-186 coiA 3.6.4.12 S Competence protein
KGFAGBON_00487 0.0 pepF E oligoendopeptidase F
KGFAGBON_00488 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
KGFAGBON_00489 4.6e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KGFAGBON_00490 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KGFAGBON_00491 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KGFAGBON_00492 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KGFAGBON_00493 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
KGFAGBON_00494 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
KGFAGBON_00495 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KGFAGBON_00496 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KGFAGBON_00497 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KGFAGBON_00498 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KGFAGBON_00499 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KGFAGBON_00500 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KGFAGBON_00501 8.5e-142 yxkH G deacetylase
KGFAGBON_00502 9.3e-239 L Transposase
KGFAGBON_00503 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KGFAGBON_00504 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KGFAGBON_00505 5.5e-153 rarD S Transporter
KGFAGBON_00506 2.2e-15 T peptidase
KGFAGBON_00507 8.9e-14 coiA 3.6.4.12 S Competence protein
KGFAGBON_00508 6.6e-147 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KGFAGBON_00509 8.3e-75 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KGFAGBON_00510 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KGFAGBON_00511 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KGFAGBON_00512 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
KGFAGBON_00513 3.3e-78 atpF C ATP synthase F(0) sector subunit b
KGFAGBON_00514 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KGFAGBON_00515 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KGFAGBON_00516 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KGFAGBON_00517 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KGFAGBON_00518 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KGFAGBON_00519 2.8e-230 ftsW D Belongs to the SEDS family
KGFAGBON_00520 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KGFAGBON_00521 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KGFAGBON_00522 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KGFAGBON_00523 6.4e-162 holB 2.7.7.7 L dna polymerase iii
KGFAGBON_00524 1.2e-135 yaaT S stage 0 sporulation protein
KGFAGBON_00525 9.5e-55 yabA L Involved in initiation control of chromosome replication
KGFAGBON_00526 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KGFAGBON_00527 2.6e-233 amt P Ammonium Transporter
KGFAGBON_00528 1.1e-53 glnB K Belongs to the P(II) protein family
KGFAGBON_00529 4.9e-106 mur1 NU mannosyl-glycoprotein
KGFAGBON_00530 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KGFAGBON_00531 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
KGFAGBON_00532 1.9e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KGFAGBON_00533 1.8e-53
KGFAGBON_00534 7.5e-26
KGFAGBON_00535 1.5e-59
KGFAGBON_00536 6.1e-63 S membrane
KGFAGBON_00537 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KGFAGBON_00538 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KGFAGBON_00539 4.5e-39 ynzC S UPF0291 protein
KGFAGBON_00540 1.8e-254 cycA E permease
KGFAGBON_00541 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
KGFAGBON_00542 5.8e-71 pts33BCA G pts system
KGFAGBON_00543 3.5e-143 pts33BCA G pts system
KGFAGBON_00544 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KGFAGBON_00545 1.2e-165 L integrase core domain
KGFAGBON_00546 6.7e-122 L Helix-turn-helix domain
KGFAGBON_00551 1.8e-167 fhuR K transcriptional regulator (lysR family)
KGFAGBON_00552 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KGFAGBON_00553 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KGFAGBON_00554 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KGFAGBON_00555 4.9e-227 pyrP F uracil Permease
KGFAGBON_00556 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KGFAGBON_00557 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KGFAGBON_00558 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KGFAGBON_00559 9.3e-239 L Transposase
KGFAGBON_00560 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
KGFAGBON_00561 3.6e-35 V efflux transmembrane transporter activity
KGFAGBON_00562 3.1e-31 V efflux transmembrane transporter activity
KGFAGBON_00563 8.2e-28 ytrF V efflux transmembrane transporter activity
KGFAGBON_00564 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KGFAGBON_00565 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KGFAGBON_00566 3.4e-77 L Transposase
KGFAGBON_00567 4.2e-111 L Transposase
KGFAGBON_00568 1.6e-18 L Integrase core domain
KGFAGBON_00569 2.2e-51 devA 3.6.3.25 V abc transporter atp-binding protein
KGFAGBON_00570 8.1e-55 devA 3.6.3.25 V abc transporter atp-binding protein
KGFAGBON_00571 9.7e-165 hrtB V MacB-like periplasmic core domain
KGFAGBON_00574 3e-92 S MucBP domain
KGFAGBON_00575 6.5e-50 M YSIRK type signal peptide
KGFAGBON_00576 0.0 M the current gene model (or a revised gene model) may contain a
KGFAGBON_00578 0.0 mdlB V abc transporter atp-binding protein
KGFAGBON_00579 0.0 lmrA V abc transporter atp-binding protein
KGFAGBON_00580 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KGFAGBON_00581 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KGFAGBON_00582 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KGFAGBON_00583 2.5e-132 rr02 KT response regulator
KGFAGBON_00584 7.1e-214 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KGFAGBON_00585 2.8e-168 V ABC transporter
KGFAGBON_00586 5.4e-122 sagI S ABC-2 type transporter
KGFAGBON_00587 2.4e-197 yceA S Belongs to the UPF0176 family
KGFAGBON_00588 1.1e-22
KGFAGBON_00589 2.8e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
KGFAGBON_00590 8.7e-114 S VIT family
KGFAGBON_00591 8.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KGFAGBON_00592 8e-221 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KGFAGBON_00593 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
KGFAGBON_00594 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KGFAGBON_00595 6.1e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KGFAGBON_00596 4.6e-105 GBS0088 J protein conserved in bacteria
KGFAGBON_00597 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KGFAGBON_00598 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KGFAGBON_00599 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
KGFAGBON_00600 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KGFAGBON_00601 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KGFAGBON_00602 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KGFAGBON_00603 2.5e-21
KGFAGBON_00604 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KGFAGBON_00606 3.5e-07 U protein secretion
KGFAGBON_00607 2.1e-50 U protein secretion
KGFAGBON_00609 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KGFAGBON_00610 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KGFAGBON_00611 4.9e-21 XK27_13030
KGFAGBON_00612 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KGFAGBON_00613 8.9e-57 S hydrolase activity, acting on ester bonds
KGFAGBON_00614 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KGFAGBON_00615 8.6e-167 S Protein of unknown function (DUF3114)
KGFAGBON_00616 1.2e-22 S Protein of unknown function (DUF3114)
KGFAGBON_00617 1.5e-118 yqfA K protein, Hemolysin III
KGFAGBON_00618 1e-25 K hmm pf08876
KGFAGBON_00619 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KGFAGBON_00620 1.7e-218 mvaS 2.3.3.10 I synthase
KGFAGBON_00621 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KGFAGBON_00622 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KGFAGBON_00623 9.7e-22
KGFAGBON_00624 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KGFAGBON_00625 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KGFAGBON_00626 5.2e-251 mmuP E amino acid
KGFAGBON_00627 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KGFAGBON_00628 1.4e-29 S Domain of unknown function (DUF1912)
KGFAGBON_00629 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
KGFAGBON_00630 3.3e-250 L Transposase
KGFAGBON_00631 1.2e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KGFAGBON_00632 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KGFAGBON_00633 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KGFAGBON_00634 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
KGFAGBON_00635 4.8e-16 S Protein of unknown function (DUF2969)
KGFAGBON_00638 6.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
KGFAGBON_00641 1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
KGFAGBON_00642 1.5e-30 S Domain of Unknown Function with PDB structure (DUF3862)
KGFAGBON_00643 1.7e-63 M Pfam SNARE associated Golgi protein
KGFAGBON_00644 6.8e-234 murN 2.3.2.10, 2.3.2.16 V FemAB family
KGFAGBON_00645 1.5e-50 S oxidoreductase
KGFAGBON_00646 2.4e-66 S oxidoreductase
KGFAGBON_00647 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
KGFAGBON_00648 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KGFAGBON_00649 0.0 clpE O Belongs to the ClpA ClpB family
KGFAGBON_00650 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KGFAGBON_00651 1.3e-34 ykuJ S protein conserved in bacteria
KGFAGBON_00652 3.1e-122 WQ51_01820 P ABC transporter, permease protein
KGFAGBON_00653 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
KGFAGBON_00654 1.1e-78 feoA P FeoA domain protein
KGFAGBON_00655 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KGFAGBON_00656 1.5e-07
KGFAGBON_00657 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KGFAGBON_00658 2.2e-45 K sequence-specific DNA binding
KGFAGBON_00659 1.5e-35 yugF I carboxylic ester hydrolase activity
KGFAGBON_00660 7.5e-23 I Alpha/beta hydrolase family
KGFAGBON_00661 2.1e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KGFAGBON_00662 3.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KGFAGBON_00663 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KGFAGBON_00664 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KGFAGBON_00666 9.2e-43 licT K transcriptional antiterminator
KGFAGBON_00667 6.8e-53 licT K transcriptional antiterminator
KGFAGBON_00668 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KGFAGBON_00669 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KGFAGBON_00670 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KGFAGBON_00671 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KGFAGBON_00672 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KGFAGBON_00673 6e-133 mdtG EGP Major facilitator Superfamily
KGFAGBON_00674 9.5e-74 mdtG EGP Major facilitator Superfamily
KGFAGBON_00675 2.6e-33 secG U Preprotein translocase subunit SecG
KGFAGBON_00676 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KGFAGBON_00677 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KGFAGBON_00678 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KGFAGBON_00679 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KGFAGBON_00680 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KGFAGBON_00681 4.4e-183 ccpA K Catabolite control protein A
KGFAGBON_00682 2.8e-28 yyaQ S YjbR
KGFAGBON_00683 6.6e-101 yyaQ V Protein conserved in bacteria
KGFAGBON_00684 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KGFAGBON_00685 1e-78 yueI S Protein of unknown function (DUF1694)
KGFAGBON_00686 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KGFAGBON_00687 2e-25 WQ51_00785
KGFAGBON_00688 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KGFAGBON_00689 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
KGFAGBON_00690 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KGFAGBON_00691 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KGFAGBON_00692 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KGFAGBON_00693 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KGFAGBON_00694 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KGFAGBON_00695 3.2e-53 yheA S Belongs to the UPF0342 family
KGFAGBON_00696 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KGFAGBON_00697 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KGFAGBON_00698 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KGFAGBON_00699 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
KGFAGBON_00700 2.6e-253 msrR K Transcriptional regulator
KGFAGBON_00701 3.5e-150 ydiA P C4-dicarboxylate transporter malic acid transport protein
KGFAGBON_00702 2.4e-203 I acyl-CoA dehydrogenase
KGFAGBON_00703 3.5e-97 mip S hydroperoxide reductase activity
KGFAGBON_00704 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KGFAGBON_00705 8.9e-20
KGFAGBON_00706 3.2e-46
KGFAGBON_00707 1e-31 K Cro/C1-type HTH DNA-binding domain
KGFAGBON_00708 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
KGFAGBON_00709 1.5e-25 estA E GDSL-like Lipase/Acylhydrolase
KGFAGBON_00710 4.4e-93
KGFAGBON_00711 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KGFAGBON_00712 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KGFAGBON_00713 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KGFAGBON_00714 2.3e-198 S CRISPR-associated protein Csn2 subfamily St
KGFAGBON_00715 1.3e-148 ycgQ S TIGR03943 family
KGFAGBON_00716 1.7e-157 XK27_03015 S permease
KGFAGBON_00718 0.0 yhgF K Transcriptional accessory protein
KGFAGBON_00719 9.9e-42 pspC KT PspC domain
KGFAGBON_00720 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KGFAGBON_00721 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KGFAGBON_00723 5.5e-69 ytxH S General stress protein
KGFAGBON_00725 4.4e-177 yegQ O Peptidase U32
KGFAGBON_00726 3.4e-252 yegQ O Peptidase U32
KGFAGBON_00727 1.5e-89 bioY S biotin synthase
KGFAGBON_00729 1.1e-33 XK27_12190 S protein conserved in bacteria
KGFAGBON_00730 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
KGFAGBON_00731 1.9e-12
KGFAGBON_00732 7.7e-238 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KGFAGBON_00733 4.2e-117
KGFAGBON_00734 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KGFAGBON_00735 1e-163 M LysM domain
KGFAGBON_00736 7.6e-16
KGFAGBON_00737 2.3e-175 S hydrolase
KGFAGBON_00738 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
KGFAGBON_00739 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KGFAGBON_00740 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
KGFAGBON_00741 2.7e-27 P Hemerythrin HHE cation binding domain protein
KGFAGBON_00742 1.6e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KGFAGBON_00743 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
KGFAGBON_00744 9.1e-27 MA20_36090 S Protein of unknown function (DUF2974)
KGFAGBON_00745 8.7e-45 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFAGBON_00746 7.6e-71 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFAGBON_00747 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KGFAGBON_00748 1.2e-216 S Bacteriophage abortive infection AbiH
KGFAGBON_00750 2.8e-221 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
KGFAGBON_00751 2.2e-105
KGFAGBON_00752 1e-136 S Protein conserved in bacteria
KGFAGBON_00753 6.6e-306 hsdM 2.1.1.72 V type I restriction-modification system
KGFAGBON_00754 5.9e-22 S PD-(D/E)XK nuclease family transposase
KGFAGBON_00755 1e-36 spd F DNA RNA non-specific endonuclease
KGFAGBON_00756 9.9e-90 spd F DNA RNA non-specific endonuclease
KGFAGBON_00757 9e-93 lemA S LemA family
KGFAGBON_00758 6.4e-133 htpX O Belongs to the peptidase M48B family
KGFAGBON_00759 1.8e-73 S Psort location CytoplasmicMembrane, score
KGFAGBON_00760 6.2e-56 S Domain of unknown function (DUF4430)
KGFAGBON_00761 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KGFAGBON_00762 1.9e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
KGFAGBON_00763 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KGFAGBON_00764 2.4e-161 L Transposase
KGFAGBON_00765 3e-50 L Transposase
KGFAGBON_00766 4.8e-196 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KGFAGBON_00767 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KGFAGBON_00768 3.2e-92 dps P Belongs to the Dps family
KGFAGBON_00769 1.1e-80 perR P Belongs to the Fur family
KGFAGBON_00770 8.4e-28 yqgQ S protein conserved in bacteria
KGFAGBON_00771 9.9e-180 glk 2.7.1.2 G Glucokinase
KGFAGBON_00772 0.0 typA T GTP-binding protein TypA
KGFAGBON_00774 9.3e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KGFAGBON_00775 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KGFAGBON_00776 6.7e-172 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KGFAGBON_00777 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KGFAGBON_00778 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KGFAGBON_00779 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KGFAGBON_00780 1.4e-96 sepF D cell septum assembly
KGFAGBON_00781 2e-34 yggT D integral membrane protein
KGFAGBON_00782 4.2e-144 ylmH T S4 RNA-binding domain
KGFAGBON_00783 1.8e-135 divIVA D Cell division protein DivIVA
KGFAGBON_00784 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KGFAGBON_00785 5.5e-30
KGFAGBON_00786 8.4e-10
KGFAGBON_00787 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
KGFAGBON_00788 2e-45 rpmE2 J 50S ribosomal protein L31
KGFAGBON_00789 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KGFAGBON_00790 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KGFAGBON_00791 2.4e-155 gst O Glutathione S-transferase
KGFAGBON_00792 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KGFAGBON_00793 4.5e-111 tdk 2.7.1.21 F thymidine kinase
KGFAGBON_00794 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KGFAGBON_00795 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KGFAGBON_00796 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KGFAGBON_00797 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KGFAGBON_00798 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
KGFAGBON_00799 6e-106 pvaA M lytic transglycosylase activity
KGFAGBON_00800 0.0 yfiB1 V abc transporter atp-binding protein
KGFAGBON_00801 0.0 XK27_10035 V abc transporter atp-binding protein
KGFAGBON_00802 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
KGFAGBON_00803 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGFAGBON_00804 4.6e-238 dltB M Membrane protein involved in D-alanine export
KGFAGBON_00805 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGFAGBON_00806 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KGFAGBON_00807 1.2e-32 L Integrase core domain protein
KGFAGBON_00808 8.7e-67 L Transposase and inactivated derivatives
KGFAGBON_00809 8.3e-18 L transposase activity
KGFAGBON_00810 0.0 3.6.3.8 P cation transport ATPase
KGFAGBON_00811 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KGFAGBON_00813 3e-44 ymbI L transposase activity
KGFAGBON_00814 4e-22 L Belongs to the 'phage' integrase family
KGFAGBON_00815 1.4e-66 S tRNA_anti-like
KGFAGBON_00816 2e-103
KGFAGBON_00818 5e-12
KGFAGBON_00820 2e-296 S DNA primase
KGFAGBON_00821 3e-164 KL Phage plasmid primase P4 family
KGFAGBON_00822 6.9e-22
KGFAGBON_00823 9.2e-13
KGFAGBON_00828 1.3e-17 K Cro/C1-type HTH DNA-binding domain
KGFAGBON_00830 1.1e-220 sip L Belongs to the 'phage' integrase family
KGFAGBON_00832 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KGFAGBON_00833 7.3e-166 metF 1.5.1.20 E reductase
KGFAGBON_00834 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KGFAGBON_00835 1.7e-94 panT S ECF transporter, substrate-specific component
KGFAGBON_00836 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KGFAGBON_00837 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KGFAGBON_00838 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KGFAGBON_00839 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFAGBON_00840 2.8e-40 T PhoQ Sensor
KGFAGBON_00841 1.7e-43 T PhoQ Sensor
KGFAGBON_00842 5.8e-79 T PhoQ Sensor
KGFAGBON_00843 6.7e-122 L Helix-turn-helix domain
KGFAGBON_00844 1.2e-165 L integrase core domain
KGFAGBON_00845 1e-190 L Transposase
KGFAGBON_00846 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
KGFAGBON_00847 8.9e-206 potD P spermidine putrescine ABC transporter
KGFAGBON_00848 3.1e-268 clcA P Chloride transporter, ClC family
KGFAGBON_00849 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
KGFAGBON_00850 3.9e-122 L Helix-turn-helix domain
KGFAGBON_00851 5.6e-166 L Integrase core domain protein
KGFAGBON_00852 1.8e-245 L Transposase
KGFAGBON_00853 2.1e-30 rpsT J rRNA binding
KGFAGBON_00854 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
KGFAGBON_00855 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
KGFAGBON_00856 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KGFAGBON_00857 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KGFAGBON_00858 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KGFAGBON_00859 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KGFAGBON_00860 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KGFAGBON_00861 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KGFAGBON_00862 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KGFAGBON_00863 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
KGFAGBON_00864 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KGFAGBON_00865 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KGFAGBON_00866 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KGFAGBON_00867 3.1e-81 ypmB S Protein conserved in bacteria
KGFAGBON_00868 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KGFAGBON_00869 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KGFAGBON_00870 9e-08
KGFAGBON_00871 2.4e-30
KGFAGBON_00872 3e-13
KGFAGBON_00873 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KGFAGBON_00874 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KGFAGBON_00875 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
KGFAGBON_00876 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KGFAGBON_00877 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KGFAGBON_00878 7.7e-20 D nuclear chromosome segregation
KGFAGBON_00879 7.4e-138 yejC S cyclic nucleotide-binding protein
KGFAGBON_00880 1.2e-163 rapZ S Displays ATPase and GTPase activities
KGFAGBON_00881 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KGFAGBON_00882 8.7e-162 whiA K May be required for sporulation
KGFAGBON_00883 2.8e-90 pepD E Dipeptidase
KGFAGBON_00884 5.8e-41 pepD E dipeptidase activity
KGFAGBON_00885 5.4e-32 cspD K Cold shock protein domain
KGFAGBON_00886 9.4e-43 K Cold-Shock Protein
KGFAGBON_00887 3.6e-224 L Transposase, Mutator family
KGFAGBON_00888 0.0 copB 3.6.3.4 P P-type ATPase
KGFAGBON_00889 4.6e-224 L Transposase, Mutator family
KGFAGBON_00890 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KGFAGBON_00891 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KGFAGBON_00892 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KGFAGBON_00893 2.6e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
KGFAGBON_00894 4.2e-225 L Transposase
KGFAGBON_00895 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
KGFAGBON_00896 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
KGFAGBON_00897 3.7e-157 glcU U Glucose uptake
KGFAGBON_00898 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
KGFAGBON_00899 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
KGFAGBON_00900 2.2e-101 XK27_10720 D peptidase activity
KGFAGBON_00901 9.2e-297 adcA P Belongs to the bacterial solute-binding protein 9 family
KGFAGBON_00902 1.7e-08
KGFAGBON_00904 1.2e-172 yeiH S Membrane
KGFAGBON_00905 5.1e-117 mur1 NU muramidase
KGFAGBON_00906 3.2e-35 L transposase activity
KGFAGBON_00907 2.6e-166 cpsY K Transcriptional regulator
KGFAGBON_00908 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KGFAGBON_00909 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
KGFAGBON_00910 2.4e-105 artQ P ABC transporter (Permease
KGFAGBON_00911 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
KGFAGBON_00912 1.1e-158 aatB ET ABC transporter substrate-binding protein
KGFAGBON_00913 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KGFAGBON_00914 2.1e-07
KGFAGBON_00915 8e-58 adhP 1.1.1.1 C alcohol dehydrogenase
KGFAGBON_00916 4.2e-113 adhP 1.1.1.1 C alcohol dehydrogenase
KGFAGBON_00917 1.1e-19 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KGFAGBON_00918 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KGFAGBON_00919 2e-126 gntR1 K transcriptional
KGFAGBON_00920 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KGFAGBON_00921 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KGFAGBON_00922 2.4e-87 niaX
KGFAGBON_00923 6e-91 niaR S small molecule binding protein (contains 3H domain)
KGFAGBON_00924 9.6e-129 K DNA-binding helix-turn-helix protein
KGFAGBON_00925 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KGFAGBON_00926 5.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KGFAGBON_00927 8.2e-168 GK ROK family
KGFAGBON_00928 8.3e-159 dprA LU DNA protecting protein DprA
KGFAGBON_00929 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KGFAGBON_00930 3.6e-154 S TraX protein
KGFAGBON_00931 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFAGBON_00932 1.3e-249 T PhoQ Sensor
KGFAGBON_00933 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KGFAGBON_00934 1.1e-152 XK27_05470 E Methionine synthase
KGFAGBON_00935 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KGFAGBON_00936 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KGFAGBON_00937 1.8e-51 IQ Acetoin reductase
KGFAGBON_00938 3.9e-19 IQ Acetoin reductase
KGFAGBON_00939 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KGFAGBON_00940 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KGFAGBON_00943 1.3e-212 pqqE C radical SAM domain protein
KGFAGBON_00944 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
KGFAGBON_00945 6.6e-61 EGP Major facilitator Superfamily
KGFAGBON_00946 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KGFAGBON_00947 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KGFAGBON_00948 1.8e-110 L Transposase
KGFAGBON_00949 4.8e-28 L Helix-turn-helix domain of transposase family ISL3
KGFAGBON_00950 6.4e-104 V ABC transporter (Permease
KGFAGBON_00951 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFAGBON_00952 1.6e-10
KGFAGBON_00953 9e-98 K Transcriptional regulator, TetR family
KGFAGBON_00954 1.8e-159 czcD P cation diffusion facilitator family transporter
KGFAGBON_00955 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KGFAGBON_00956 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KGFAGBON_00957 6e-08 S Hydrolases of the alpha beta superfamily
KGFAGBON_00958 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
KGFAGBON_00959 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
KGFAGBON_00962 1.2e-143 2.4.2.3 F Phosphorylase superfamily
KGFAGBON_00963 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KGFAGBON_00964 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
KGFAGBON_00965 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
KGFAGBON_00967 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KGFAGBON_00968 3.7e-190
KGFAGBON_00969 8.1e-90 FNV0100 F Belongs to the Nudix hydrolase family
KGFAGBON_00970 3.5e-28 3.4.13.21 I Protein conserved in bacteria
KGFAGBON_00972 4.3e-118 S TraX protein
KGFAGBON_00973 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KGFAGBON_00974 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KGFAGBON_00975 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KGFAGBON_00976 6e-188 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KGFAGBON_00977 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KGFAGBON_00978 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
KGFAGBON_00979 1.1e-204 csm1 S CRISPR-associated protein Csm1 family
KGFAGBON_00980 1.2e-210 csm1 S CRISPR-associated protein Csm1 family
KGFAGBON_00981 2.5e-62 csm2 L Csm2 Type III-A
KGFAGBON_00982 1.6e-117 csm3 L RAMP superfamily
KGFAGBON_00983 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
KGFAGBON_00984 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
KGFAGBON_00986 9.5e-32 csm6 S Psort location Cytoplasmic, score
KGFAGBON_00987 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KGFAGBON_00988 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KGFAGBON_00989 5.5e-267 dtpT E transporter
KGFAGBON_00990 1.4e-62 yecS P ABC transporter (Permease
KGFAGBON_00991 2.3e-20 yecS P amino acid transport
KGFAGBON_00993 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KGFAGBON_00994 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
KGFAGBON_00995 4e-99 yfiF3 K sequence-specific DNA binding
KGFAGBON_00996 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KGFAGBON_00997 1.8e-240 agcS E (Alanine) symporter
KGFAGBON_00998 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KGFAGBON_00999 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
KGFAGBON_01000 1.8e-59 Q phosphatase activity
KGFAGBON_01001 9.3e-62 S haloacid dehalogenase-like hydrolase
KGFAGBON_01002 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KGFAGBON_01003 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KGFAGBON_01004 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
KGFAGBON_01005 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
KGFAGBON_01006 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KGFAGBON_01007 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KGFAGBON_01008 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KGFAGBON_01009 1.9e-43 yktA S Belongs to the UPF0223 family
KGFAGBON_01010 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KGFAGBON_01011 7.9e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KGFAGBON_01012 3.3e-158 pstS P phosphate
KGFAGBON_01013 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
KGFAGBON_01014 1.2e-155 pstA P phosphate transport system permease
KGFAGBON_01015 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KGFAGBON_01016 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KGFAGBON_01017 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
KGFAGBON_01018 0.0 pepN 3.4.11.2 E aminopeptidase
KGFAGBON_01019 8.3e-196 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KGFAGBON_01020 2.9e-187 lplA 6.3.1.20 H Lipoate-protein ligase
KGFAGBON_01023 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KGFAGBON_01024 1.2e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KGFAGBON_01025 1.3e-48 malR K Transcriptional regulator
KGFAGBON_01026 2.3e-23 L Transposase
KGFAGBON_01027 4.6e-25 tatA U protein secretion
KGFAGBON_01028 9e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KGFAGBON_01029 7.2e-303 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KGFAGBON_01030 8.7e-234 ycdB P peroxidase
KGFAGBON_01031 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
KGFAGBON_01032 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
KGFAGBON_01033 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
KGFAGBON_01034 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFAGBON_01035 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KGFAGBON_01036 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KGFAGBON_01037 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KGFAGBON_01038 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KGFAGBON_01039 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KGFAGBON_01040 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KGFAGBON_01041 8.6e-187 3.5.1.28 M GBS Bsp-like repeat
KGFAGBON_01042 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KGFAGBON_01043 6.4e-11 3.5.1.28 NU amidase activity
KGFAGBON_01044 0.0 lpdA 1.8.1.4 C Dehydrogenase
KGFAGBON_01045 1.1e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KGFAGBON_01046 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KGFAGBON_01047 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KGFAGBON_01048 1.1e-37 P membrane protein (DUF2207)
KGFAGBON_01049 4.4e-66 S the current gene model (or a revised gene model) may contain a frame shift
KGFAGBON_01050 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KGFAGBON_01051 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KGFAGBON_01052 3e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KGFAGBON_01053 3.8e-17 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
KGFAGBON_01054 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
KGFAGBON_01055 1.3e-125 3.4.16.4 M Belongs to the peptidase S11 family
KGFAGBON_01056 1.3e-159 rssA S Phospholipase, patatin family
KGFAGBON_01057 6.1e-79 estA E GDSL-like protein
KGFAGBON_01058 2.6e-15 estA E Lysophospholipase L1 and related esterases
KGFAGBON_01059 2e-294 S unusual protein kinase
KGFAGBON_01060 4.9e-39 S granule-associated protein
KGFAGBON_01061 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KGFAGBON_01062 3.5e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KGFAGBON_01063 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KGFAGBON_01064 1.3e-199 S hmm pf01594
KGFAGBON_01065 3.9e-61 G Belongs to the phosphoglycerate mutase family
KGFAGBON_01066 3.5e-29 G Belongs to the phosphoglycerate mutase family
KGFAGBON_01067 7.6e-70 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
KGFAGBON_01068 1.4e-96 V VanZ like family
KGFAGBON_01069 3e-167 L Transposase
KGFAGBON_01070 1.9e-13
KGFAGBON_01071 3e-246 cps1C S Polysaccharide biosynthesis protein
KGFAGBON_01072 7.9e-45 tnp L DDE domain
KGFAGBON_01073 1.1e-183 M Glycosyltransferase, group 2 family protein
KGFAGBON_01075 5.8e-202 cps1B GT2,GT4 M Glycosyl transferases group 1
KGFAGBON_01076 7.6e-174 rgpB GT2 S Glycosyl transferase family 2
KGFAGBON_01077 4.6e-202 GT4 M Glycosyltransferase, group 1 family protein
KGFAGBON_01078 2e-91 pssE S Glycosyltransferase family 28 C-terminal domain
KGFAGBON_01079 3.3e-88 cpsF M Oligosaccharide biosynthesis protein Alg14 like
KGFAGBON_01080 2.4e-31 rgpAc GT4 M Domain of unknown function (DUF1972)
KGFAGBON_01081 7.5e-258 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KGFAGBON_01082 9.7e-119 cpsD D COG0489 ATPases involved in chromosome partitioning
KGFAGBON_01083 1.9e-116 cps4C M biosynthesis protein
KGFAGBON_01084 4.6e-137 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KGFAGBON_01085 8e-258 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KGFAGBON_01086 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KGFAGBON_01087 1.5e-30 yfeJ 6.3.5.2 F glutamine amidotransferase
KGFAGBON_01088 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
KGFAGBON_01089 9.4e-66 clcA_2 P chloride
KGFAGBON_01090 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KGFAGBON_01091 8.1e-41 S Protein of unknown function (DUF1697)
KGFAGBON_01092 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KGFAGBON_01093 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KGFAGBON_01095 6.1e-22 V Glucan-binding protein C
KGFAGBON_01096 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
KGFAGBON_01097 2.1e-276 pepV 3.5.1.18 E Dipeptidase
KGFAGBON_01098 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KGFAGBON_01099 6.9e-86 XK27_03610 K Gnat family
KGFAGBON_01100 4.7e-24 L Transposase
KGFAGBON_01101 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KGFAGBON_01102 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KGFAGBON_01103 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KGFAGBON_01104 6.6e-122 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KGFAGBON_01105 3.9e-15 M LysM domain
KGFAGBON_01106 2.9e-90 ebsA S Family of unknown function (DUF5322)
KGFAGBON_01107 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KGFAGBON_01108 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KGFAGBON_01109 3.7e-224 G COG0457 FOG TPR repeat
KGFAGBON_01110 2.8e-24 yubA S permease
KGFAGBON_01111 5.9e-132 yubA S permease
KGFAGBON_01112 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KGFAGBON_01113 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KGFAGBON_01114 2.5e-124 ftsE D cell division ATP-binding protein FtsE
KGFAGBON_01115 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KGFAGBON_01116 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KGFAGBON_01117 1.1e-180 yjjH S Calcineurin-like phosphoesterase
KGFAGBON_01118 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KGFAGBON_01119 0.0 pacL 3.6.3.8 P cation transport ATPase
KGFAGBON_01120 2.6e-67 ywiB S Domain of unknown function (DUF1934)
KGFAGBON_01121 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
KGFAGBON_01122 1.2e-146 yidA S hydrolases of the HAD superfamily
KGFAGBON_01123 1.8e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KGFAGBON_01124 5e-35 F Protein of unknown function (DUF454)
KGFAGBON_01125 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KGFAGBON_01126 1.5e-247 vicK 2.7.13.3 T Histidine kinase
KGFAGBON_01127 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFAGBON_01128 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
KGFAGBON_01129 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KGFAGBON_01130 5.9e-118 gltJ P ABC transporter (Permease
KGFAGBON_01131 1.7e-111 tcyB_2 P ABC transporter (permease)
KGFAGBON_01132 2.4e-124 endA F DNA RNA non-specific endonuclease
KGFAGBON_01133 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
KGFAGBON_01134 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KGFAGBON_01136 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KGFAGBON_01137 2.2e-21 G Domain of unknown function (DUF4832)
KGFAGBON_01138 8.4e-53 G Domain of unknown function (DUF4832)
KGFAGBON_01139 1.5e-211 cotH M CotH kinase protein
KGFAGBON_01140 2.3e-49 pelG S Putative exopolysaccharide Exporter (EPS-E)
KGFAGBON_01141 3.8e-199 pelG M Putative exopolysaccharide Exporter (EPS-E)
KGFAGBON_01142 4.3e-277 pelF GT4 M Domain of unknown function (DUF3492)
KGFAGBON_01143 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
KGFAGBON_01144 2.2e-168
KGFAGBON_01145 0.0 5.1.3.2 GM Psort location CytoplasmicMembrane, score
KGFAGBON_01146 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KGFAGBON_01147 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KGFAGBON_01148 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KGFAGBON_01149 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KGFAGBON_01150 4.2e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KGFAGBON_01151 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
KGFAGBON_01154 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KGFAGBON_01155 3.2e-220 XK27_05110 P chloride
KGFAGBON_01156 5.1e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KGFAGBON_01157 6.4e-282 clcA P Chloride transporter, ClC family
KGFAGBON_01158 2.3e-75 fld C Flavodoxin
KGFAGBON_01159 5.5e-14 XK27_08880
KGFAGBON_01160 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
KGFAGBON_01161 9.2e-152 estA CE1 S Putative esterase
KGFAGBON_01162 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KGFAGBON_01163 1.2e-135 XK27_08845 S abc transporter atp-binding protein
KGFAGBON_01164 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KGFAGBON_01165 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
KGFAGBON_01166 3.2e-17 S Domain of unknown function (DUF4649)
KGFAGBON_01168 1.1e-43 Q the current gene model (or a revised gene model) may contain a frame shift
KGFAGBON_01169 7e-27 Q the current gene model (or a revised gene model) may contain a frame shift
KGFAGBON_01172 1.6e-249 L Transposase
KGFAGBON_01173 1.1e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KGFAGBON_01174 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KGFAGBON_01175 0.0 dnaE 2.7.7.7 L DNA polymerase
KGFAGBON_01176 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
KGFAGBON_01177 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KGFAGBON_01178 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KGFAGBON_01179 2.5e-43 ysdA L Membrane
KGFAGBON_01180 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KGFAGBON_01181 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KGFAGBON_01182 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KGFAGBON_01183 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KGFAGBON_01185 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KGFAGBON_01186 2.1e-84 ypmS S Protein conserved in bacteria
KGFAGBON_01187 9.4e-17 ypmR E lipolytic protein G-D-S-L family
KGFAGBON_01188 7.7e-71 ypmR E COG2755 Lysophospholipase L1 and related esterases
KGFAGBON_01189 1e-148 DegV S DegV family
KGFAGBON_01190 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
KGFAGBON_01191 3.7e-73 argR K Regulates arginine biosynthesis genes
KGFAGBON_01192 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KGFAGBON_01193 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KGFAGBON_01194 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
KGFAGBON_01195 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KGFAGBON_01198 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KGFAGBON_01199 2.9e-125 dnaD
KGFAGBON_01200 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KGFAGBON_01201 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KGFAGBON_01202 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KGFAGBON_01203 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KGFAGBON_01204 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KGFAGBON_01205 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KGFAGBON_01206 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KGFAGBON_01207 5.4e-197 L transposase, IS4 family
KGFAGBON_01208 5.6e-240 rodA D Belongs to the SEDS family
KGFAGBON_01209 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
KGFAGBON_01210 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KGFAGBON_01211 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KGFAGBON_01212 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KGFAGBON_01213 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KGFAGBON_01214 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KGFAGBON_01215 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KGFAGBON_01216 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KGFAGBON_01217 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KGFAGBON_01218 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KGFAGBON_01220 6.6e-31 L Integrase core domain protein
KGFAGBON_01221 1.6e-55 L transposition
KGFAGBON_01222 8.2e-22 L Transposase
KGFAGBON_01223 5.2e-36 L transposase activity
KGFAGBON_01224 1.3e-22 XK27_08085
KGFAGBON_01225 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KGFAGBON_01226 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KGFAGBON_01227 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KGFAGBON_01228 1.1e-121 ylfI S tigr01906
KGFAGBON_01229 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KGFAGBON_01230 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
KGFAGBON_01231 1.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KGFAGBON_01234 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KGFAGBON_01235 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KGFAGBON_01236 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KGFAGBON_01237 1.6e-207 yurR 1.4.5.1 E oxidoreductase
KGFAGBON_01238 6.4e-29 zupT P transporter
KGFAGBON_01239 2.3e-14 zupT P Mediates zinc uptake. May also transport other divalent cations
KGFAGBON_01240 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KGFAGBON_01241 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KGFAGBON_01242 1.7e-70 gtrA S GtrA-like protein
KGFAGBON_01243 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KGFAGBON_01244 6e-169 ybbR S Protein conserved in bacteria
KGFAGBON_01245 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KGFAGBON_01246 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KGFAGBON_01247 8.7e-150 cobQ S glutamine amidotransferase
KGFAGBON_01248 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KGFAGBON_01249 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
KGFAGBON_01250 0.0 uup S abc transporter atp-binding protein
KGFAGBON_01251 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KGFAGBON_01252 9.3e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
KGFAGBON_01253 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KGFAGBON_01254 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KGFAGBON_01255 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KGFAGBON_01256 7.9e-39 ptsH G phosphocarrier protein Hpr
KGFAGBON_01257 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
KGFAGBON_01258 6.7e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
KGFAGBON_01259 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KGFAGBON_01260 2.2e-34 nrdH O Glutaredoxin
KGFAGBON_01261 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KGFAGBON_01262 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KGFAGBON_01264 4.2e-71 L Transposase (IS116 IS110 IS902 family)
KGFAGBON_01265 1.8e-165 ypuA S secreted protein
KGFAGBON_01266 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
KGFAGBON_01267 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KGFAGBON_01268 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KGFAGBON_01269 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KGFAGBON_01270 3.4e-258 noxE P NADH oxidase
KGFAGBON_01271 1.9e-294 yfmM S abc transporter atp-binding protein
KGFAGBON_01272 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
KGFAGBON_01273 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KGFAGBON_01274 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KGFAGBON_01275 2e-86 S ECF-type riboflavin transporter, S component
KGFAGBON_01277 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KGFAGBON_01278 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KGFAGBON_01280 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KGFAGBON_01281 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGFAGBON_01282 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KGFAGBON_01283 0.0 smc D Required for chromosome condensation and partitioning
KGFAGBON_01284 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KGFAGBON_01285 2.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KGFAGBON_01286 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KGFAGBON_01287 7.3e-82 alkD L Dna alkylation repair
KGFAGBON_01288 2.8e-93 pat 2.3.1.183 M acetyltransferase
KGFAGBON_01289 3e-13
KGFAGBON_01290 6.8e-30
KGFAGBON_01291 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KGFAGBON_01292 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KGFAGBON_01293 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KGFAGBON_01294 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
KGFAGBON_01295 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
KGFAGBON_01296 2.3e-27
KGFAGBON_01297 7.6e-146 S ABC-2 family transporter protein
KGFAGBON_01298 4.1e-150 S transport system, permease component
KGFAGBON_01299 1.8e-102 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGFAGBON_01300 4.2e-195 desK 2.7.13.3 T Histidine kinase
KGFAGBON_01301 7.4e-135 yvfS V ABC-2 type transporter
KGFAGBON_01302 2.1e-160 XK27_09825 V 'abc transporter, ATP-binding protein
KGFAGBON_01306 2.3e-213 EGP Major facilitator Superfamily
KGFAGBON_01307 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
KGFAGBON_01308 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
KGFAGBON_01309 3.9e-41 3.6.1.55 F NUDIX domain
KGFAGBON_01311 3.7e-122 S An automated process has identified a potential problem with this gene model
KGFAGBON_01312 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
KGFAGBON_01313 1.6e-14 liaI KT membrane
KGFAGBON_01314 2.6e-30 liaI KT membrane
KGFAGBON_01315 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
KGFAGBON_01316 0.0 V ABC transporter (permease)
KGFAGBON_01317 5.8e-135 macB2 V ABC transporter, ATP-binding protein
KGFAGBON_01318 6.2e-166 T Histidine kinase
KGFAGBON_01319 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KGFAGBON_01320 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KGFAGBON_01322 3.3e-69 pbuX F xanthine permease
KGFAGBON_01323 9.2e-119 pbuX F xanthine permease
KGFAGBON_01324 5.3e-248 norM V Multidrug efflux pump
KGFAGBON_01325 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KGFAGBON_01326 7.8e-236 brnQ E Component of the transport system for branched-chain amino acids
KGFAGBON_01327 2.9e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
KGFAGBON_01328 2.8e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
KGFAGBON_01329 9.6e-26 csbD K CsbD-like
KGFAGBON_01330 1.5e-245 yfnA E amino acid
KGFAGBON_01331 6.1e-111 XK27_02070 S nitroreductase
KGFAGBON_01332 2.1e-154 1.13.11.2 S glyoxalase
KGFAGBON_01333 3.3e-77 ywnA K Transcriptional regulator
KGFAGBON_01334 6.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
KGFAGBON_01335 2.4e-234 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGFAGBON_01336 1.3e-111 drgA C Nitroreductase
KGFAGBON_01337 5.1e-122 yoaK S Protein of unknown function (DUF1275)
KGFAGBON_01338 3.1e-161 yvgN C reductase
KGFAGBON_01339 5.6e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KGFAGBON_01340 2.4e-09
KGFAGBON_01341 1.6e-140 S Abortive infection C-terminus
KGFAGBON_01342 0.0 L DEAD-like helicases superfamily
KGFAGBON_01343 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KGFAGBON_01344 2.7e-285 XK27_07020 S Belongs to the UPF0371 family
KGFAGBON_01346 1.1e-37 BP1961 P nitric oxide dioxygenase activity
KGFAGBON_01347 1.6e-53 K response regulator
KGFAGBON_01348 9.3e-72 S Signal peptide protein, YSIRK family
KGFAGBON_01349 4.5e-61
KGFAGBON_01350 5.5e-272 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KGFAGBON_01351 1.9e-35
KGFAGBON_01352 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
KGFAGBON_01353 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
KGFAGBON_01354 5.8e-109 MA20_06410 E LysE type translocator
KGFAGBON_01355 5.6e-08
KGFAGBON_01356 2.7e-09
KGFAGBON_01357 0.0 M family 8
KGFAGBON_01359 7.4e-165 hrtB V MacB-like periplasmic core domain
KGFAGBON_01360 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
KGFAGBON_01361 1.1e-151 V MatE
KGFAGBON_01363 1.5e-109 C Fe-S oxidoreductases
KGFAGBON_01364 1.2e-176 EGP Major Facilitator Superfamily
KGFAGBON_01365 5.5e-258 I radical SAM domain protein
KGFAGBON_01367 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KGFAGBON_01368 1.4e-150 L Integrase core domain protein
KGFAGBON_01369 1.8e-87 L transposase activity
KGFAGBON_01371 1.5e-61
KGFAGBON_01372 0.0 sbcC L ATPase involved in DNA repair
KGFAGBON_01373 5.3e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KGFAGBON_01374 0.0 lacL 3.2.1.23 G -beta-galactosidase
KGFAGBON_01375 0.0 lacS G transporter
KGFAGBON_01376 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KGFAGBON_01377 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KGFAGBON_01378 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KGFAGBON_01379 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KGFAGBON_01380 1.8e-184 galR K Transcriptional regulator
KGFAGBON_01381 2.7e-08 L Integrase core domain protein
KGFAGBON_01382 1.2e-25 L transposition
KGFAGBON_01383 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KGFAGBON_01384 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KGFAGBON_01385 2.5e-101 V abc transporter atp-binding protein
KGFAGBON_01386 4.3e-40 V abc transporter atp-binding protein
KGFAGBON_01387 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KGFAGBON_01388 2.3e-87 L Transposase
KGFAGBON_01389 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KGFAGBON_01390 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KGFAGBON_01391 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KGFAGBON_01392 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KGFAGBON_01395 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KGFAGBON_01396 6.5e-111 vraS 2.7.13.3 T Histidine kinase
KGFAGBON_01397 9e-51 vraS 2.7.13.3 T Histidine kinase
KGFAGBON_01398 3.7e-120 yvqF KT membrane
KGFAGBON_01399 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KGFAGBON_01400 9e-133 stp 3.1.3.16 T phosphatase
KGFAGBON_01401 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KGFAGBON_01402 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KGFAGBON_01403 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KGFAGBON_01404 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KGFAGBON_01405 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KGFAGBON_01406 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KGFAGBON_01407 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
KGFAGBON_01408 2.1e-148 supH S overlaps another CDS with the same product name
KGFAGBON_01409 8.6e-63 yvoA_1 K Transcriptional
KGFAGBON_01410 9.8e-121 skfE V abc transporter atp-binding protein
KGFAGBON_01411 5.6e-133 V ATPase activity
KGFAGBON_01412 4.3e-172 oppF P Belongs to the ABC transporter superfamily
KGFAGBON_01413 2.2e-204 oppD P Belongs to the ABC transporter superfamily
KGFAGBON_01414 4.9e-168 amiD P ABC transporter (Permease
KGFAGBON_01415 4.2e-278 amiC P ABC transporter (Permease
KGFAGBON_01416 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KGFAGBON_01417 1.6e-224 L Transposase
KGFAGBON_01418 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KGFAGBON_01419 8.1e-45 L Transposase
KGFAGBON_01420 4.1e-158 L COG2801 Transposase and inactivated derivatives
KGFAGBON_01421 1e-23 oppF P Belongs to the ABC transporter superfamily
KGFAGBON_01422 3.8e-45 oppF P Belongs to the ABC transporter superfamily
KGFAGBON_01423 1.4e-40 tatD L Hydrolase, tatd
KGFAGBON_01424 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
KGFAGBON_01425 1e-110 L Integrase core domain protein
KGFAGBON_01426 1.1e-23 L transposase activity
KGFAGBON_01427 8.9e-18 L transposase activity
KGFAGBON_01428 8.2e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KGFAGBON_01429 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KGFAGBON_01430 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KGFAGBON_01431 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KGFAGBON_01432 1.5e-103 yjbK S Adenylate cyclase
KGFAGBON_01433 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KGFAGBON_01434 2.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
KGFAGBON_01435 3.1e-59 XK27_04120 S Putative amino acid metabolism
KGFAGBON_01436 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KGFAGBON_01437 7.2e-132 puuD T peptidase C26
KGFAGBON_01438 1.2e-115 radC E Belongs to the UPF0758 family
KGFAGBON_01439 1.7e-268 M Psort location CytoplasmicMembrane, score
KGFAGBON_01440 0.0 rgpF M Rhamnan synthesis protein F
KGFAGBON_01441 2e-305 GT4 M transferase activity, transferring glycosyl groups
KGFAGBON_01442 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KGFAGBON_01443 2.1e-143 rgpC GM Transport permease protein
KGFAGBON_01444 4.9e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
KGFAGBON_01445 1.8e-228 rgpA GT4 M Domain of unknown function (DUF1972)
KGFAGBON_01446 8.2e-153 2.4.1.60 S Glycosyltransferase group 2 family protein
KGFAGBON_01447 4.6e-42 S Uncharacterized conserved protein (DUF2304)
KGFAGBON_01448 6.9e-130 arnC M group 2 family protein
KGFAGBON_01449 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
KGFAGBON_01450 9.3e-186 S Glycosyltransferase like family 2
KGFAGBON_01451 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
KGFAGBON_01452 6.9e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KGFAGBON_01453 5.3e-237 S Predicted membrane protein (DUF2142)
KGFAGBON_01454 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KGFAGBON_01455 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KGFAGBON_01456 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KGFAGBON_01457 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KGFAGBON_01458 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KGFAGBON_01459 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
KGFAGBON_01460 1.6e-202 arcT 2.6.1.1 E Aminotransferase
KGFAGBON_01461 6.5e-137 ET ABC transporter
KGFAGBON_01462 7.5e-144 ET Belongs to the bacterial solute-binding protein 3 family
KGFAGBON_01463 2.9e-84 mutT 3.6.1.55 F Nudix family
KGFAGBON_01464 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KGFAGBON_01465 2.5e-56 V CAAX protease self-immunity
KGFAGBON_01466 2.4e-33 S CAAX amino terminal protease family protein
KGFAGBON_01467 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KGFAGBON_01468 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
KGFAGBON_01469 1.1e-16 XK27_00735
KGFAGBON_01470 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KGFAGBON_01472 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KGFAGBON_01475 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
KGFAGBON_01476 4.7e-51 ycaO O OsmC-like protein
KGFAGBON_01477 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
KGFAGBON_01479 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
KGFAGBON_01480 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KGFAGBON_01481 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KGFAGBON_01482 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KGFAGBON_01483 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
KGFAGBON_01484 1.8e-287 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KGFAGBON_01485 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KGFAGBON_01486 2.6e-109 3.1.3.18 S IA, variant 1
KGFAGBON_01487 2.2e-117 lrgB M effector of murein hydrolase
KGFAGBON_01488 7.7e-56 lrgA S Effector of murein hydrolase LrgA
KGFAGBON_01490 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
KGFAGBON_01491 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KGFAGBON_01492 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGFAGBON_01493 3.9e-104 wecD M Acetyltransferase GNAT family
KGFAGBON_01494 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KGFAGBON_01495 4.6e-58 GK ROK family
KGFAGBON_01496 2.1e-25 GK ROK family
KGFAGBON_01497 1.1e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
KGFAGBON_01498 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
KGFAGBON_01499 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
KGFAGBON_01500 2.3e-206 potD P spermidine putrescine ABC transporter
KGFAGBON_01501 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
KGFAGBON_01502 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
KGFAGBON_01503 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KGFAGBON_01504 7.8e-171 murB 1.3.1.98 M cell wall formation
KGFAGBON_01505 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KGFAGBON_01506 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KGFAGBON_01507 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KGFAGBON_01508 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KGFAGBON_01509 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
KGFAGBON_01510 0.0 ydaO E amino acid
KGFAGBON_01511 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KGFAGBON_01512 4.1e-37 ylqC L Belongs to the UPF0109 family
KGFAGBON_01513 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KGFAGBON_01514 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KGFAGBON_01515 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
KGFAGBON_01516 2.1e-74 S QueT transporter
KGFAGBON_01517 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KGFAGBON_01518 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KGFAGBON_01519 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KGFAGBON_01520 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KGFAGBON_01521 2.2e-85 ccl S cog cog4708
KGFAGBON_01522 5.8e-161 rbn E Belongs to the UPF0761 family
KGFAGBON_01523 1.9e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KGFAGBON_01524 3e-232 ytoI K transcriptional regulator containing CBS domains
KGFAGBON_01525 1.1e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KGFAGBON_01526 1.5e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KGFAGBON_01527 0.0 comEC S Competence protein ComEC
KGFAGBON_01528 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KGFAGBON_01529 1.7e-142 plsC 2.3.1.51 I Acyltransferase
KGFAGBON_01530 1.8e-140 nodB3 G deacetylase
KGFAGBON_01531 7.1e-141 yabB 2.1.1.223 L Methyltransferase
KGFAGBON_01532 1e-41 yazA L endonuclease containing a URI domain
KGFAGBON_01533 2.4e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KGFAGBON_01534 2.3e-154 corA P CorA-like protein
KGFAGBON_01535 1.9e-62 yjqA S Bacterial PH domain
KGFAGBON_01536 2.3e-99 thiT S Thiamine transporter
KGFAGBON_01537 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KGFAGBON_01538 1.9e-201 yjbB G Permeases of the major facilitator superfamily
KGFAGBON_01539 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KGFAGBON_01540 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
KGFAGBON_01541 1e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KGFAGBON_01545 1.1e-155 cjaA ET ABC transporter substrate-binding protein
KGFAGBON_01546 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KGFAGBON_01547 3.5e-115 P ABC transporter (Permease
KGFAGBON_01548 1e-114 papP P ABC transporter (Permease
KGFAGBON_01549 9.3e-239 L Transposase
KGFAGBON_01550 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KGFAGBON_01551 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
KGFAGBON_01552 0.0 copA 3.6.3.54 P P-type ATPase
KGFAGBON_01553 3.2e-74 copY K Copper transport repressor, CopY TcrY family
KGFAGBON_01554 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KGFAGBON_01555 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KGFAGBON_01556 1.4e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KGFAGBON_01557 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KGFAGBON_01558 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KGFAGBON_01559 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KGFAGBON_01560 8.7e-259 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KGFAGBON_01561 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
KGFAGBON_01562 1.8e-245 L Transposase
KGFAGBON_01563 1.7e-51
KGFAGBON_01564 0.0 ctpE P E1-E2 ATPase
KGFAGBON_01565 3.9e-26
KGFAGBON_01566 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KGFAGBON_01567 5.1e-47 L transposase activity
KGFAGBON_01568 1.4e-81 K transcriptional regulator, MerR family
KGFAGBON_01569 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
KGFAGBON_01570 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
KGFAGBON_01571 7.4e-64 XK27_02560 S cog cog2151
KGFAGBON_01572 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KGFAGBON_01573 7.7e-227 ytfP S Flavoprotein
KGFAGBON_01575 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KGFAGBON_01576 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
KGFAGBON_01577 2.7e-183 ecsB U ABC transporter
KGFAGBON_01578 2.3e-133 ecsA V abc transporter atp-binding protein
KGFAGBON_01579 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KGFAGBON_01580 6e-11
KGFAGBON_01581 1.3e-56 S CD20-like family
KGFAGBON_01582 3.2e-110
KGFAGBON_01583 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KGFAGBON_01584 6.9e-206 ylbM S Belongs to the UPF0348 family
KGFAGBON_01585 2e-140 yqeM Q Methyltransferase domain protein
KGFAGBON_01586 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KGFAGBON_01587 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KGFAGBON_01588 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KGFAGBON_01589 3.5e-49 yhbY J RNA-binding protein
KGFAGBON_01590 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KGFAGBON_01591 1.8e-98 yqeG S hydrolase of the HAD superfamily
KGFAGBON_01592 1.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KGFAGBON_01593 5.8e-24
KGFAGBON_01594 3.5e-13
KGFAGBON_01595 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KGFAGBON_01596 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KGFAGBON_01597 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KGFAGBON_01598 1.5e-25 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
KGFAGBON_01599 1.3e-251 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KGFAGBON_01600 6.7e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KGFAGBON_01601 1.6e-154 hlpA M Belongs to the NlpA lipoprotein family
KGFAGBON_01602 6.8e-101 pncA Q isochorismatase
KGFAGBON_01603 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KGFAGBON_01604 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KGFAGBON_01605 2.4e-75 XK27_03180 T universal stress protein
KGFAGBON_01608 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KGFAGBON_01609 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KGFAGBON_01610 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KGFAGBON_01611 0.0 yjcE P NhaP-type Na H and K H antiporters
KGFAGBON_01613 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
KGFAGBON_01614 1.3e-184 yhcC S radical SAM protein
KGFAGBON_01615 2.2e-196 ylbL T Belongs to the peptidase S16 family
KGFAGBON_01616 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KGFAGBON_01617 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
KGFAGBON_01618 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KGFAGBON_01619 1.9e-09 S Protein of unknown function (DUF4059)
KGFAGBON_01620 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
KGFAGBON_01621 4.7e-163 yxeN P ABC transporter (Permease
KGFAGBON_01622 1.2e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KGFAGBON_01624 1.4e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KGFAGBON_01625 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KGFAGBON_01626 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
KGFAGBON_01627 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGFAGBON_01628 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
KGFAGBON_01629 2.9e-87 D nuclear chromosome segregation
KGFAGBON_01630 1.5e-127 ybbM S transport system, permease component
KGFAGBON_01631 1.2e-117 ybbL S abc transporter atp-binding protein
KGFAGBON_01632 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KGFAGBON_01633 4.6e-140 cppA E CppA N-terminal
KGFAGBON_01634 5e-44 V CAAX protease self-immunity
KGFAGBON_01635 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KGFAGBON_01636 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KGFAGBON_01639 3e-47 spiA K sequence-specific DNA binding
KGFAGBON_01640 2.9e-28 blpT
KGFAGBON_01641 6.7e-98 blpT
KGFAGBON_01648 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
KGFAGBON_01652 7.4e-135 agrA KT phosphorelay signal transduction system
KGFAGBON_01653 3.4e-239 blpH 2.7.13.3 T protein histidine kinase activity
KGFAGBON_01655 7.3e-237 mesE M Transport protein ComB
KGFAGBON_01656 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KGFAGBON_01657 0.0 mdlB V abc transporter atp-binding protein
KGFAGBON_01658 9.1e-303 mdlA V abc transporter atp-binding protein
KGFAGBON_01660 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
KGFAGBON_01661 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KGFAGBON_01662 3.6e-70 yutD J protein conserved in bacteria
KGFAGBON_01663 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KGFAGBON_01665 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KGFAGBON_01666 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KGFAGBON_01667 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KGFAGBON_01668 4.3e-47 ftsL D cell division protein FtsL
KGFAGBON_01669 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KGFAGBON_01670 1.6e-65
KGFAGBON_01671 7.4e-27
KGFAGBON_01672 2.6e-30
KGFAGBON_01674 9.7e-32 yhaI J Protein of unknown function (DUF805)
KGFAGBON_01675 1.3e-08 D nuclear chromosome segregation
KGFAGBON_01676 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KGFAGBON_01677 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KGFAGBON_01678 6.2e-288 XK27_00765
KGFAGBON_01679 1.4e-133 ecsA_2 V abc transporter atp-binding protein
KGFAGBON_01680 2.5e-47 S Protein of unknown function (DUF554)
KGFAGBON_01681 8.5e-32 S Protein of unknown function (DUF554)
KGFAGBON_01682 1.6e-11 S Protein of unknown function (DUF554)
KGFAGBON_01683 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KGFAGBON_01684 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KGFAGBON_01685 2.6e-121 liaI S membrane
KGFAGBON_01686 5.2e-75 XK27_02470 K LytTr DNA-binding domain
KGFAGBON_01687 3.6e-66 KT response to antibiotic
KGFAGBON_01688 2.6e-80 yebC M Membrane
KGFAGBON_01689 2.9e-18 yebC M Membrane
KGFAGBON_01690 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
KGFAGBON_01691 6.2e-174 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KGFAGBON_01693 1.1e-250 L Transposase
KGFAGBON_01694 3.7e-151 K Helix-turn-helix XRE-family like proteins
KGFAGBON_01695 9.2e-284 V ABC transporter transmembrane region
KGFAGBON_01696 2.9e-31 yozG K Transcriptional regulator
KGFAGBON_01699 2.1e-185 V Abi-like protein
KGFAGBON_01701 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KGFAGBON_01702 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KGFAGBON_01703 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KGFAGBON_01704 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KGFAGBON_01705 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KGFAGBON_01706 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KGFAGBON_01708 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KGFAGBON_01709 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KGFAGBON_01710 0.0 scrA 2.7.1.211 G pts system
KGFAGBON_01711 5.4e-291 scrB 3.2.1.26 GH32 G invertase
KGFAGBON_01712 7.5e-180 scrR K Transcriptional
KGFAGBON_01713 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KGFAGBON_01714 3.4e-62 yqhY S protein conserved in bacteria
KGFAGBON_01715 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KGFAGBON_01716 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
KGFAGBON_01717 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KGFAGBON_01719 8e-44 V 'abc transporter, ATP-binding protein
KGFAGBON_01720 3.8e-58 V 'abc transporter, ATP-binding protein
KGFAGBON_01723 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KGFAGBON_01724 2e-169 corA P COG0598 Mg2 and Co2 transporters
KGFAGBON_01725 3.1e-124 XK27_01040 S Pfam PF06570
KGFAGBON_01727 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KGFAGBON_01728 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KGFAGBON_01729 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KGFAGBON_01730 3.6e-41 XK27_05745
KGFAGBON_01731 2.5e-230 mutY L A G-specific adenine glycosylase
KGFAGBON_01736 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KGFAGBON_01737 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KGFAGBON_01738 1e-93 cvpA S toxin biosynthetic process
KGFAGBON_01739 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KGFAGBON_01740 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KGFAGBON_01741 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KGFAGBON_01742 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KGFAGBON_01743 2e-47 azlD E branched-chain amino acid
KGFAGBON_01744 1.3e-117 azlC E AzlC protein
KGFAGBON_01745 1.1e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KGFAGBON_01746 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KGFAGBON_01747 4.3e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KGFAGBON_01748 2.5e-33 ykzG S Belongs to the UPF0356 family
KGFAGBON_01749 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KGFAGBON_01750 2.7e-40 pscB M CHAP domain protein
KGFAGBON_01751 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
KGFAGBON_01752 8.5e-63 glnR K Transcriptional regulator
KGFAGBON_01753 1.3e-87 S Fusaric acid resistance protein-like
KGFAGBON_01754 3e-13
KGFAGBON_01755 8.9e-30
KGFAGBON_01756 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KGFAGBON_01757 3.2e-42 L Transposase
KGFAGBON_01758 1.9e-46 L transposase activity
KGFAGBON_01759 7.4e-23 L Transposase
KGFAGBON_01760 1.8e-56 L transposition
KGFAGBON_01761 9.1e-83 L Integrase core domain protein
KGFAGBON_01762 1e-102 L Transposase
KGFAGBON_01763 1.7e-111 L Transposase
KGFAGBON_01764 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KGFAGBON_01765 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KGFAGBON_01766 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KGFAGBON_01767 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KGFAGBON_01768 1.1e-142 purR 2.4.2.7 F operon repressor
KGFAGBON_01769 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
KGFAGBON_01770 6.9e-173 rmuC S RmuC domain protein
KGFAGBON_01771 1.8e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
KGFAGBON_01772 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KGFAGBON_01773 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KGFAGBON_01775 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KGFAGBON_01776 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KGFAGBON_01777 1.4e-144 tatD L Hydrolase, tatd
KGFAGBON_01778 2.5e-26 yccU S CoA-binding protein
KGFAGBON_01779 4.8e-51 trxA O Belongs to the thioredoxin family
KGFAGBON_01780 7.8e-143 S Macro domain protein
KGFAGBON_01781 3.1e-10 L thioesterase
KGFAGBON_01782 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
KGFAGBON_01785 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KGFAGBON_01786 1e-33 L Transposase
KGFAGBON_01787 1e-13 rpmH J Ribosomal protein L34
KGFAGBON_01788 2e-186 jag S RNA-binding protein
KGFAGBON_01789 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KGFAGBON_01790 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KGFAGBON_01791 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
KGFAGBON_01792 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KGFAGBON_01793 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KGFAGBON_01794 6.7e-81 amiA E transmembrane transport
KGFAGBON_01795 2e-41 amiA E transmembrane transport
KGFAGBON_01796 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
KGFAGBON_01797 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
KGFAGBON_01798 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KGFAGBON_01799 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KGFAGBON_01800 9.2e-51 S Protein of unknown function (DUF3397)
KGFAGBON_01801 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KGFAGBON_01802 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
KGFAGBON_01803 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
KGFAGBON_01804 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
KGFAGBON_01805 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KGFAGBON_01806 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KGFAGBON_01807 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
KGFAGBON_01808 4.3e-77 XK27_09620 S reductase
KGFAGBON_01809 9e-62 XK27_09615 C reductase
KGFAGBON_01810 1e-141 XK27_09615 C reductase
KGFAGBON_01811 3.2e-62 fnt P Formate nitrite transporter
KGFAGBON_01812 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
KGFAGBON_01813 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KGFAGBON_01814 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KGFAGBON_01815 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KGFAGBON_01816 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KGFAGBON_01817 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KGFAGBON_01818 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KGFAGBON_01819 2.7e-48 S glycolate biosynthetic process
KGFAGBON_01820 1.5e-64 S phosphatase activity
KGFAGBON_01821 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
KGFAGBON_01824 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KGFAGBON_01825 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KGFAGBON_01826 8.3e-37 yeeD O sulfur carrier activity
KGFAGBON_01827 2.8e-193 yeeE S Sulphur transport
KGFAGBON_01828 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KGFAGBON_01829 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KGFAGBON_01830 4.1e-09 S Domain of unknown function (DUF4651)
KGFAGBON_01831 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KGFAGBON_01832 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KGFAGBON_01833 1.8e-111 S CAAX amino terminal protease family protein
KGFAGBON_01835 5e-67 V CAAX protease self-immunity
KGFAGBON_01836 1.4e-33 V CAAX protease self-immunity
KGFAGBON_01837 8.8e-27 lanR K sequence-specific DNA binding
KGFAGBON_01838 9.8e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KGFAGBON_01839 5.9e-177 ytxK 2.1.1.72 L DNA methylase
KGFAGBON_01840 2e-12 comGF U Putative Competence protein ComGF
KGFAGBON_01841 1.5e-71 comGF U Competence protein ComGF
KGFAGBON_01842 1.4e-15 NU Type II secretory pathway pseudopilin
KGFAGBON_01843 1.8e-57 cglD NU Competence protein
KGFAGBON_01844 8.5e-43 comGC U Required for transformation and DNA binding
KGFAGBON_01845 1.1e-156 cglB U protein transport across the cell outer membrane
KGFAGBON_01846 4.5e-177 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KGFAGBON_01847 1e-68 S cog cog4699
KGFAGBON_01848 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGFAGBON_01849 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGFAGBON_01850 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KGFAGBON_01851 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KGFAGBON_01852 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KGFAGBON_01853 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
KGFAGBON_01854 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KGFAGBON_01855 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KGFAGBON_01857 9.3e-239 L Transposase
KGFAGBON_01858 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
KGFAGBON_01859 1.8e-57 asp S cog cog1302
KGFAGBON_01860 3.2e-226 norN V Mate efflux family protein
KGFAGBON_01861 6.4e-279 thrC 4.2.3.1 E Threonine synthase
KGFAGBON_01862 5.5e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KGFAGBON_01863 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
KGFAGBON_01864 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KGFAGBON_01865 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KGFAGBON_01866 3.1e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
KGFAGBON_01867 0.0 pepO 3.4.24.71 O Peptidase family M13
KGFAGBON_01868 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KGFAGBON_01869 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KGFAGBON_01870 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KGFAGBON_01871 1.4e-54 treB 2.7.1.201 G PTS System
KGFAGBON_01872 5.8e-21 treR K DNA-binding transcription factor activity
KGFAGBON_01873 1.2e-85 treR K trehalose operon
KGFAGBON_01874 3.3e-95 ywlG S Belongs to the UPF0340 family
KGFAGBON_01876 1.8e-127 tnp L Transposase
KGFAGBON_01877 2e-20 S phage tail
KGFAGBON_01878 7.1e-130 S EcsC protein family
KGFAGBON_01879 2.4e-23 S phage tail tape measure protein
KGFAGBON_01880 9.8e-71 L Phage integrase family
KGFAGBON_01882 4.2e-72 L PFAM Integrase, catalytic core
KGFAGBON_01883 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
KGFAGBON_01885 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
KGFAGBON_01886 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
KGFAGBON_01887 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
KGFAGBON_01888 3.3e-09 L PFAM Integrase, catalytic core
KGFAGBON_01889 1.8e-111 L PFAM Integrase, catalytic core
KGFAGBON_01890 3.3e-62 rplQ J ribosomal protein l17
KGFAGBON_01891 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGFAGBON_01892 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KGFAGBON_01893 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KGFAGBON_01894 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KGFAGBON_01895 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KGFAGBON_01896 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KGFAGBON_01897 2.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KGFAGBON_01898 4.4e-58 rplO J binds to the 23S rRNA
KGFAGBON_01899 2.5e-23 rpmD J ribosomal protein l30
KGFAGBON_01900 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KGFAGBON_01901 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KGFAGBON_01902 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KGFAGBON_01903 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KGFAGBON_01904 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KGFAGBON_01905 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KGFAGBON_01906 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KGFAGBON_01907 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KGFAGBON_01908 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KGFAGBON_01909 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KGFAGBON_01910 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KGFAGBON_01911 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KGFAGBON_01912 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KGFAGBON_01913 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KGFAGBON_01914 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KGFAGBON_01915 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KGFAGBON_01916 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
KGFAGBON_01917 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KGFAGBON_01918 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KGFAGBON_01919 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KGFAGBON_01920 0.0 XK27_09800 I Acyltransferase
KGFAGBON_01921 1.7e-35 XK27_09805 S MORN repeat protein
KGFAGBON_01922 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KGFAGBON_01923 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KGFAGBON_01924 8.8e-83 adk 2.7.4.3 F topology modulation protein
KGFAGBON_01925 3.1e-172 yxaM EGP Major facilitator Superfamily
KGFAGBON_01926 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
KGFAGBON_01927 4.8e-54 L Transposase
KGFAGBON_01928 4.1e-147 L Transposase
KGFAGBON_01930 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KGFAGBON_01931 0.0 KLT serine threonine protein kinase
KGFAGBON_01932 2.1e-280 V ABC transporter
KGFAGBON_01933 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KGFAGBON_01934 1.4e-127 Z012_04635 K sequence-specific DNA binding
KGFAGBON_01936 3.4e-191 C Radical SAM
KGFAGBON_01937 3.9e-287 V ABC transporter transmembrane region
KGFAGBON_01938 1.7e-90 K sequence-specific DNA binding
KGFAGBON_01939 1.3e-36 L Replication initiation factor
KGFAGBON_01940 5e-93 L Replication initiation factor
KGFAGBON_01941 1.9e-18 S Domain of unknown function (DUF3173)
KGFAGBON_01942 3.5e-216 int L Belongs to the 'phage' integrase family
KGFAGBON_01944 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KGFAGBON_01945 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KGFAGBON_01946 2.8e-44 yrzL S Belongs to the UPF0297 family
KGFAGBON_01947 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KGFAGBON_01948 4.2e-44 yrzB S Belongs to the UPF0473 family
KGFAGBON_01949 9.3e-239 L Transposase
KGFAGBON_01950 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
KGFAGBON_01951 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KGFAGBON_01952 7.5e-14
KGFAGBON_01953 2.6e-91 XK27_10930 K acetyltransferase
KGFAGBON_01954 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KGFAGBON_01955 1.8e-147 yaaA S Belongs to the UPF0246 family
KGFAGBON_01956 9.9e-169 XK27_01785 S cog cog1284
KGFAGBON_01957 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KGFAGBON_01959 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
KGFAGBON_01960 5.7e-52 metE 2.1.1.14 E Methionine synthase
KGFAGBON_01961 7.6e-64 metE 2.1.1.14 E Methionine synthase
KGFAGBON_01962 9.2e-36 metE 2.1.1.14 E Methionine synthase
KGFAGBON_01963 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KGFAGBON_01964 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KGFAGBON_01966 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
KGFAGBON_01967 2.7e-95 S Hydrophobic domain protein
KGFAGBON_01969 3.7e-27 S Membrane
KGFAGBON_01970 3.1e-101
KGFAGBON_01971 1.8e-23 S Small integral membrane protein
KGFAGBON_01972 1.1e-71 M Protein conserved in bacteria
KGFAGBON_01973 4.9e-12 K CsbD-like
KGFAGBON_01974 7.2e-95 nudL L hydrolase
KGFAGBON_01975 3.4e-13 nudL L hydrolase
KGFAGBON_01976 4e-19 K negative regulation of transcription, DNA-templated
KGFAGBON_01977 1.7e-23 K negative regulation of transcription, DNA-templated
KGFAGBON_01979 3.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
KGFAGBON_01980 1.8e-88 S Putative adhesin
KGFAGBON_01981 3.9e-161 XK27_06930 V domain protein
KGFAGBON_01982 6.4e-96 XK27_06935 K transcriptional regulator
KGFAGBON_01983 4.8e-55 ypaA M Membrane
KGFAGBON_01984 2.7e-08
KGFAGBON_01985 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KGFAGBON_01986 8.2e-48 veg S Biofilm formation stimulator VEG
KGFAGBON_01987 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KGFAGBON_01988 3.9e-70 rplI J binds to the 23S rRNA
KGFAGBON_01989 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KGFAGBON_01990 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KGFAGBON_01991 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KGFAGBON_01992 0.0 S Bacterial membrane protein, YfhO
KGFAGBON_01993 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
KGFAGBON_01994 3.1e-93 lytE M LysM domain protein
KGFAGBON_01995 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGFAGBON_01996 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGFAGBON_01997 7.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGFAGBON_01998 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KGFAGBON_01999 3.7e-138 ymfM S sequence-specific DNA binding
KGFAGBON_02000 1.1e-242 ymfH S Peptidase M16
KGFAGBON_02001 4.8e-235 ymfF S Peptidase M16
KGFAGBON_02002 1.6e-45 yaaA S S4 domain protein YaaA
KGFAGBON_02003 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KGFAGBON_02004 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KGFAGBON_02005 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KGFAGBON_02006 1.1e-153 yvjA S membrane
KGFAGBON_02007 6.7e-306 ybiT S abc transporter atp-binding protein
KGFAGBON_02008 0.0 XK27_10405 S Bacterial membrane protein YfhO
KGFAGBON_02012 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
KGFAGBON_02013 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KGFAGBON_02014 1.5e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KGFAGBON_02015 1e-134 parB K Belongs to the ParB family
KGFAGBON_02018 8.7e-17 D DNA segregation ATPase FtsK SpoIIIE
KGFAGBON_02019 3.3e-22 L Replication initiation factor
KGFAGBON_02021 1.8e-72 hsp O Belongs to the small heat shock protein (HSP20) family
KGFAGBON_02022 2.8e-179 L Replication protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)