ORF_ID e_value Gene_name EC_number CAZy COGs Description
MCPNGMEK_00001 4.1e-144 L IstB-like ATP binding protein
MCPNGMEK_00002 2.2e-145 L PFAM Integrase catalytic
MCPNGMEK_00003 1e-114 L PFAM Integrase catalytic
MCPNGMEK_00004 7e-103
MCPNGMEK_00005 1.1e-19
MCPNGMEK_00006 5.4e-160 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
MCPNGMEK_00007 1.7e-27 rom S Rop protein
MCPNGMEK_00008 3.7e-44 L DNA integration
MCPNGMEK_00009 6e-16 virB4 U multi-organism process
MCPNGMEK_00010 1.2e-214 tetA EGP Sugar (and other) transporter
MCPNGMEK_00011 1.4e-144 cobB2 K Sir2 family
MCPNGMEK_00012 1.3e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MCPNGMEK_00013 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MCPNGMEK_00014 1.2e-145 ypfH S Phospholipase/Carboxylesterase
MCPNGMEK_00015 0.0 yjcE P Sodium/hydrogen exchanger family
MCPNGMEK_00016 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
MCPNGMEK_00017 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
MCPNGMEK_00018 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
MCPNGMEK_00020 9.9e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCPNGMEK_00021 1e-270 KLT Domain of unknown function (DUF4032)
MCPNGMEK_00022 3.7e-154
MCPNGMEK_00023 2e-180 3.4.22.70 M Sortase family
MCPNGMEK_00024 1.7e-285 M LPXTG-motif cell wall anchor domain protein
MCPNGMEK_00025 0.0 S LPXTG-motif cell wall anchor domain protein
MCPNGMEK_00026 6.6e-104 L Helix-turn-helix domain
MCPNGMEK_00027 3.3e-211 ugpC E Belongs to the ABC transporter superfamily
MCPNGMEK_00028 1.2e-174 K Psort location Cytoplasmic, score
MCPNGMEK_00029 0.0 KLT Protein tyrosine kinase
MCPNGMEK_00030 4.9e-151 O Thioredoxin
MCPNGMEK_00032 7.7e-211 S G5
MCPNGMEK_00033 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MCPNGMEK_00034 9.9e-170 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MCPNGMEK_00035 6.7e-113 S LytR cell envelope-related transcriptional attenuator
MCPNGMEK_00036 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
MCPNGMEK_00037 5.2e-124 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
MCPNGMEK_00038 0.0 M Conserved repeat domain
MCPNGMEK_00039 0.0 murJ KLT MviN-like protein
MCPNGMEK_00040 6.3e-205 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MCPNGMEK_00041 1.8e-243 parB K Belongs to the ParB family
MCPNGMEK_00042 3.8e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
MCPNGMEK_00043 9.1e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MCPNGMEK_00044 5e-93 jag S Putative single-stranded nucleic acids-binding domain
MCPNGMEK_00045 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
MCPNGMEK_00046 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MCPNGMEK_00047 4.1e-300 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MCPNGMEK_00048 7.9e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MCPNGMEK_00049 2.1e-241 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MCPNGMEK_00050 3.2e-93 S Protein of unknown function (DUF721)
MCPNGMEK_00051 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCPNGMEK_00052 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCPNGMEK_00053 3.6e-73 S Transmembrane domain of unknown function (DUF3566)
MCPNGMEK_00054 6.5e-14 abfA1 3.2.1.55 GH51 G arabinose metabolic process
MCPNGMEK_00056 2.7e-187 G Glycosyl hydrolases family 43
MCPNGMEK_00057 2.9e-189 K Periplasmic binding protein domain
MCPNGMEK_00058 1.2e-227 I Serine aminopeptidase, S33
MCPNGMEK_00059 1.5e-08 K helix_turn _helix lactose operon repressor
MCPNGMEK_00061 1.9e-24 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MCPNGMEK_00062 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MCPNGMEK_00063 2.5e-124 gntR K FCD
MCPNGMEK_00064 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MCPNGMEK_00065 0.0 3.2.1.55 GH51 G arabinose metabolic process
MCPNGMEK_00068 0.0 G Glycosyl hydrolase family 20, domain 2
MCPNGMEK_00069 3e-190 K helix_turn _helix lactose operon repressor
MCPNGMEK_00070 8.6e-78 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MCPNGMEK_00071 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
MCPNGMEK_00072 1.6e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MCPNGMEK_00073 3.5e-137 S Protein of unknown function DUF45
MCPNGMEK_00074 1.9e-83 dps P Belongs to the Dps family
MCPNGMEK_00075 1.3e-188 yddG EG EamA-like transporter family
MCPNGMEK_00076 1.2e-241 ytfL P Transporter associated domain
MCPNGMEK_00077 4.5e-97 K helix_turn _helix lactose operon repressor
MCPNGMEK_00078 6.9e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MCPNGMEK_00079 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
MCPNGMEK_00080 0.0 trxB1 1.8.1.9 C Thioredoxin domain
MCPNGMEK_00081 1.3e-309 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCPNGMEK_00082 4.3e-239 yhjX EGP Major facilitator Superfamily
MCPNGMEK_00083 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MCPNGMEK_00084 0.0 yjjP S Threonine/Serine exporter, ThrE
MCPNGMEK_00085 1.1e-155 S Amidohydrolase family
MCPNGMEK_00086 5.2e-17 S Amidohydrolase family
MCPNGMEK_00087 1.8e-195 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCPNGMEK_00088 6.5e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCPNGMEK_00089 1e-47 S Protein of unknown function (DUF3073)
MCPNGMEK_00090 7e-92 K LytTr DNA-binding domain
MCPNGMEK_00091 1.4e-22 T protein histidine kinase activity
MCPNGMEK_00092 3.2e-65 T protein histidine kinase activity
MCPNGMEK_00093 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MCPNGMEK_00094 1.4e-30 I transferase activity, transferring acyl groups other than amino-acyl groups
MCPNGMEK_00095 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
MCPNGMEK_00096 3.8e-176 rfbJ M Glycosyl transferase family 2
MCPNGMEK_00097 0.0
MCPNGMEK_00098 7.2e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MCPNGMEK_00099 0.0 3.6.4.12 K Putative DNA-binding domain
MCPNGMEK_00100 1.6e-290 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MCPNGMEK_00101 4.4e-45 L Transposase DDE domain
MCPNGMEK_00102 7.1e-98 L transposase activity
MCPNGMEK_00103 1.2e-39 L transposition
MCPNGMEK_00104 3.6e-55 L PFAM Integrase catalytic
MCPNGMEK_00105 2.5e-155 L Transposase, Mutator family
MCPNGMEK_00106 2.9e-170 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MCPNGMEK_00107 8.7e-131 rgpC U Transport permease protein
MCPNGMEK_00108 1.3e-208 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
MCPNGMEK_00109 5e-295 S Tetratricopeptide repeat
MCPNGMEK_00110 0.0 rgpF M Rhamnan synthesis protein F
MCPNGMEK_00111 5.2e-195 M Glycosyltransferase like family 2
MCPNGMEK_00112 1.1e-45
MCPNGMEK_00113 2.3e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
MCPNGMEK_00114 8e-70 S Protein of unknown function (DUF4235)
MCPNGMEK_00115 1.8e-138 G Phosphoglycerate mutase family
MCPNGMEK_00118 1e-190 K Psort location Cytoplasmic, score
MCPNGMEK_00119 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
MCPNGMEK_00120 0.0 dnaK O Heat shock 70 kDa protein
MCPNGMEK_00121 1.4e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MCPNGMEK_00122 2.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
MCPNGMEK_00123 6.8e-87 hspR K transcriptional regulator, MerR family
MCPNGMEK_00124 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
MCPNGMEK_00125 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
MCPNGMEK_00126 1.1e-139 S HAD hydrolase, family IA, variant 3
MCPNGMEK_00128 2.7e-126 dedA S SNARE associated Golgi protein
MCPNGMEK_00129 4.6e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MCPNGMEK_00130 8.6e-59
MCPNGMEK_00131 3.6e-130
MCPNGMEK_00132 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MCPNGMEK_00133 4.8e-85 K Transcriptional regulator
MCPNGMEK_00135 1.7e-276 xylR 5.3.1.12 G MFS/sugar transport protein
MCPNGMEK_00136 5.9e-185 tatD L TatD related DNase
MCPNGMEK_00137 0.0 kup P Transport of potassium into the cell
MCPNGMEK_00139 3.3e-166 S Glutamine amidotransferase domain
MCPNGMEK_00140 2.1e-137 T HD domain
MCPNGMEK_00141 7.4e-186 V ABC transporter
MCPNGMEK_00142 1e-249 V ABC transporter permease
MCPNGMEK_00143 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
MCPNGMEK_00144 0.0 S Psort location Cytoplasmic, score 8.87
MCPNGMEK_00145 6.4e-165 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MCPNGMEK_00146 8.7e-27 thiS 2.8.1.10 H ThiS family
MCPNGMEK_00148 2.3e-262
MCPNGMEK_00149 9e-209 S Glycosyltransferase, group 2 family protein
MCPNGMEK_00150 9.1e-59 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MCPNGMEK_00151 2.9e-99
MCPNGMEK_00152 2.2e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
MCPNGMEK_00153 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MCPNGMEK_00155 5.2e-153 cpaE D bacterial-type flagellum organization
MCPNGMEK_00156 9.8e-191 cpaF U Type II IV secretion system protein
MCPNGMEK_00157 5.1e-122 U Type ii secretion system
MCPNGMEK_00158 3.1e-17 gspF NU Type II secretion system (T2SS), protein F
MCPNGMEK_00159 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
MCPNGMEK_00160 1.9e-41 S Protein of unknown function (DUF4244)
MCPNGMEK_00161 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
MCPNGMEK_00162 2.2e-215 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
MCPNGMEK_00163 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
MCPNGMEK_00164 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MCPNGMEK_00165 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MCPNGMEK_00166 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
MCPNGMEK_00168 2.6e-213 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MCPNGMEK_00169 1.7e-116
MCPNGMEK_00170 1.2e-288 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MCPNGMEK_00171 2.3e-15 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MCPNGMEK_00172 2.2e-281 S Calcineurin-like phosphoesterase
MCPNGMEK_00173 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MCPNGMEK_00174 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MCPNGMEK_00175 2.4e-233 glf 5.4.99.9 M UDP-galactopyranose mutase
MCPNGMEK_00176 1.4e-122 yplQ S Haemolysin-III related
MCPNGMEK_00177 0.0 vpr M PA domain
MCPNGMEK_00178 6.7e-188 3.6.1.27 I PAP2 superfamily
MCPNGMEK_00179 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MCPNGMEK_00180 1.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MCPNGMEK_00181 6.3e-213 holB 2.7.7.7 L DNA polymerase III
MCPNGMEK_00182 4.4e-200 K helix_turn _helix lactose operon repressor
MCPNGMEK_00183 5e-38 ptsH G PTS HPr component phosphorylation site
MCPNGMEK_00184 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MCPNGMEK_00185 6.9e-161 S Fic/DOC family
MCPNGMEK_00186 1.4e-203 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MCPNGMEK_00187 6.9e-23 G MFS/sugar transport protein
MCPNGMEK_00188 7.3e-311 efeU_1 P Iron permease FTR1 family
MCPNGMEK_00189 6.4e-109 tpd P Fe2+ transport protein
MCPNGMEK_00190 1.4e-234 S Predicted membrane protein (DUF2318)
MCPNGMEK_00191 9.7e-223 macB_2 V ABC transporter permease
MCPNGMEK_00192 2.2e-206 Z012_06715 V FtsX-like permease family
MCPNGMEK_00193 5.7e-149 macB V ABC transporter, ATP-binding protein
MCPNGMEK_00194 1.3e-70 S FMN_bind
MCPNGMEK_00195 3.6e-131 yydK K UTRA
MCPNGMEK_00196 1.6e-10 S haloacid dehalogenase-like hydrolase
MCPNGMEK_00197 2.9e-69 S haloacid dehalogenase-like hydrolase
MCPNGMEK_00198 7.3e-250 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCPNGMEK_00199 4.3e-49 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MCPNGMEK_00200 7.5e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MCPNGMEK_00201 1.2e-295 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
MCPNGMEK_00202 1.2e-35 Q phosphatase activity
MCPNGMEK_00203 7e-81
MCPNGMEK_00204 3.5e-241 S Putative ABC-transporter type IV
MCPNGMEK_00205 2.1e-162 S Sucrose-6F-phosphate phosphohydrolase
MCPNGMEK_00207 2e-180 3.4.22.70 M Sortase family
MCPNGMEK_00208 9e-217 M chlorophyll binding
MCPNGMEK_00209 1.7e-191 M chlorophyll binding
MCPNGMEK_00210 5.8e-305 M LPXTG cell wall anchor motif
MCPNGMEK_00211 2.7e-82 K Winged helix DNA-binding domain
MCPNGMEK_00212 1.8e-301 V ABC transporter, ATP-binding protein
MCPNGMEK_00213 0.0 V ABC transporter transmembrane region
MCPNGMEK_00214 1.6e-84
MCPNGMEK_00215 1.2e-70 XK26_04485 P Cobalt transport protein
MCPNGMEK_00217 1.9e-305 pepD E Peptidase family C69
MCPNGMEK_00218 0.0 S Glycosyl hydrolases related to GH101 family, GH129
MCPNGMEK_00219 1.5e-197 XK27_01805 M Glycosyltransferase like family 2
MCPNGMEK_00220 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
MCPNGMEK_00222 2.3e-205 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MCPNGMEK_00223 4.1e-221 amt U Ammonium Transporter Family
MCPNGMEK_00224 1e-54 glnB K Nitrogen regulatory protein P-II
MCPNGMEK_00225 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
MCPNGMEK_00226 8.2e-252 dinF V MatE
MCPNGMEK_00227 7.5e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MCPNGMEK_00228 3.5e-283 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
MCPNGMEK_00229 5.7e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MCPNGMEK_00230 3.5e-19 S granule-associated protein
MCPNGMEK_00231 0.0 ubiB S ABC1 family
MCPNGMEK_00232 0.0 pacS 3.6.3.54 P E1-E2 ATPase
MCPNGMEK_00233 9.6e-43 csoR S Metal-sensitive transcriptional repressor
MCPNGMEK_00234 1.3e-214 rmuC S RmuC family
MCPNGMEK_00235 3.5e-129 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MCPNGMEK_00236 2e-158 spoU 2.1.1.185 J RNA methyltransferase TrmH family
MCPNGMEK_00237 1.3e-60 V ABC transporter
MCPNGMEK_00238 6.4e-90 V ABC transporter
MCPNGMEK_00239 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCPNGMEK_00240 1.1e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MCPNGMEK_00241 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCPNGMEK_00242 1.7e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
MCPNGMEK_00243 2.5e-52 S Protein of unknown function (DUF2469)
MCPNGMEK_00244 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
MCPNGMEK_00245 0.0 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MCPNGMEK_00246 7.2e-236 E Aminotransferase class I and II
MCPNGMEK_00247 9.1e-90 lrp_3 K helix_turn_helix ASNC type
MCPNGMEK_00248 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
MCPNGMEK_00249 0.0 S domain protein
MCPNGMEK_00250 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MCPNGMEK_00251 1.1e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
MCPNGMEK_00252 3e-127 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MCPNGMEK_00253 2e-135 KT Transcriptional regulatory protein, C terminal
MCPNGMEK_00254 1.4e-125
MCPNGMEK_00255 1.3e-102 mntP P Probably functions as a manganese efflux pump
MCPNGMEK_00257 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MCPNGMEK_00258 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MCPNGMEK_00259 0.0 K RNA polymerase II activating transcription factor binding
MCPNGMEK_00260 9.2e-36
MCPNGMEK_00262 4.1e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MCPNGMEK_00263 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
MCPNGMEK_00265 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCPNGMEK_00266 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MCPNGMEK_00267 2.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCPNGMEK_00268 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MCPNGMEK_00269 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MCPNGMEK_00270 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MCPNGMEK_00271 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MCPNGMEK_00272 3e-119 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MCPNGMEK_00273 5.9e-146 QT PucR C-terminal helix-turn-helix domain
MCPNGMEK_00274 0.0
MCPNGMEK_00275 1.4e-153 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MCPNGMEK_00276 4.2e-93 bioY S BioY family
MCPNGMEK_00277 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MCPNGMEK_00278 7.2e-308 pccB I Carboxyl transferase domain
MCPNGMEK_00279 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
MCPNGMEK_00280 2e-100 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MCPNGMEK_00281 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MCPNGMEK_00283 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
MCPNGMEK_00284 4e-119
MCPNGMEK_00285 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MCPNGMEK_00286 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MCPNGMEK_00287 4e-152 xylR K purine nucleotide biosynthetic process
MCPNGMEK_00288 2.3e-41 K purine nucleotide biosynthetic process
MCPNGMEK_00289 3.7e-94 lemA S LemA family
MCPNGMEK_00290 0.0 S Predicted membrane protein (DUF2207)
MCPNGMEK_00291 4e-77 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MCPNGMEK_00292 1.8e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCPNGMEK_00293 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCPNGMEK_00294 2.2e-99 nrdI F Probably involved in ribonucleotide reductase function
MCPNGMEK_00295 2.8e-41 nrdH O Glutaredoxin
MCPNGMEK_00296 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
MCPNGMEK_00297 7.2e-103 L Transposase and inactivated derivatives IS30 family
MCPNGMEK_00298 0.0 yegQ O Peptidase family U32 C-terminal domain
MCPNGMEK_00299 2.9e-190 yfiH Q Multi-copper polyphenol oxidoreductase laccase
MCPNGMEK_00300 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MCPNGMEK_00301 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MCPNGMEK_00302 3.7e-53 D nuclear chromosome segregation
MCPNGMEK_00303 2.5e-269 pepC 3.4.22.40 E Peptidase C1-like family
MCPNGMEK_00304 9.6e-173 L Excalibur calcium-binding domain
MCPNGMEK_00305 1.1e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MCPNGMEK_00306 3e-246 EGP Major facilitator Superfamily
MCPNGMEK_00307 9.7e-109 K helix_turn_helix, Arsenical Resistance Operon Repressor
MCPNGMEK_00308 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MCPNGMEK_00309 8.7e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MCPNGMEK_00310 7.2e-245 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MCPNGMEK_00311 3.4e-129 KT Transcriptional regulatory protein, C terminal
MCPNGMEK_00312 2.3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
MCPNGMEK_00313 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
MCPNGMEK_00314 4.8e-180 pstA P Phosphate transport system permease
MCPNGMEK_00315 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MCPNGMEK_00316 3e-170 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCPNGMEK_00317 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCPNGMEK_00318 8.8e-222 pbuO S Permease family
MCPNGMEK_00320 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
MCPNGMEK_00321 2.5e-186 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
MCPNGMEK_00322 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MCPNGMEK_00323 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MCPNGMEK_00325 1.6e-246 T Forkhead associated domain
MCPNGMEK_00326 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
MCPNGMEK_00327 9.6e-42
MCPNGMEK_00328 5.6e-110 flgA NO SAF
MCPNGMEK_00329 3.2e-38 fmdB S Putative regulatory protein
MCPNGMEK_00330 1.8e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
MCPNGMEK_00331 2.3e-149 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
MCPNGMEK_00332 6.3e-148
MCPNGMEK_00333 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MCPNGMEK_00334 2.1e-132 bla1 3.5.2.6 V Beta-lactamase enzyme family
MCPNGMEK_00335 6.9e-44 KLT Associated with various cellular activities
MCPNGMEK_00339 1.9e-25 rpmG J Ribosomal protein L33
MCPNGMEK_00340 6.9e-215 murB 1.3.1.98 M Cell wall formation
MCPNGMEK_00341 9e-61 fdxA C 4Fe-4S binding domain
MCPNGMEK_00342 8.5e-226 dapC E Aminotransferase class I and II
MCPNGMEK_00343 2.3e-240 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MCPNGMEK_00345 1.1e-256 M Bacterial capsule synthesis protein PGA_cap
MCPNGMEK_00346 6.2e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
MCPNGMEK_00347 3e-120
MCPNGMEK_00348 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MCPNGMEK_00349 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MCPNGMEK_00350 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
MCPNGMEK_00351 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MCPNGMEK_00352 1e-234 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MCPNGMEK_00353 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MCPNGMEK_00354 8.7e-167 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MCPNGMEK_00355 2.3e-170 ywiC S YwiC-like protein
MCPNGMEK_00356 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
MCPNGMEK_00357 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MCPNGMEK_00358 3e-119 rplD J Forms part of the polypeptide exit tunnel
MCPNGMEK_00359 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MCPNGMEK_00360 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MCPNGMEK_00361 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MCPNGMEK_00362 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MCPNGMEK_00363 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MCPNGMEK_00364 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MCPNGMEK_00365 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
MCPNGMEK_00366 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MCPNGMEK_00367 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MCPNGMEK_00368 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MCPNGMEK_00369 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MCPNGMEK_00370 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCPNGMEK_00371 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MCPNGMEK_00372 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MCPNGMEK_00373 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MCPNGMEK_00374 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MCPNGMEK_00375 1e-24 rpmD J Ribosomal protein L30p/L7e
MCPNGMEK_00376 2.7e-63 rplO J binds to the 23S rRNA
MCPNGMEK_00377 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MCPNGMEK_00378 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MCPNGMEK_00379 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MCPNGMEK_00380 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MCPNGMEK_00381 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MCPNGMEK_00382 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MCPNGMEK_00383 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCPNGMEK_00384 2.8e-64 rplQ J Ribosomal protein L17
MCPNGMEK_00385 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
MCPNGMEK_00386 8.3e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MCPNGMEK_00387 0.0 gcs2 S A circularly permuted ATPgrasp
MCPNGMEK_00388 1.3e-153 E Transglutaminase/protease-like homologues
MCPNGMEK_00390 3.4e-131 L Transposase and inactivated derivatives
MCPNGMEK_00391 1.6e-161
MCPNGMEK_00392 2.8e-188 nusA K Participates in both transcription termination and antitermination
MCPNGMEK_00393 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MCPNGMEK_00394 4.7e-84 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MCPNGMEK_00395 1.6e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MCPNGMEK_00396 1.7e-232 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
MCPNGMEK_00397 6.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MCPNGMEK_00398 3.6e-106
MCPNGMEK_00400 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MCPNGMEK_00401 2.9e-204 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCPNGMEK_00402 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
MCPNGMEK_00403 3.2e-300 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MCPNGMEK_00404 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MCPNGMEK_00406 6.1e-43 M Spy0128-like isopeptide containing domain
MCPNGMEK_00407 4.5e-45 M Spy0128-like isopeptide containing domain
MCPNGMEK_00408 0.0 crr G pts system, glucose-specific IIABC component
MCPNGMEK_00409 1.3e-151 arbG K CAT RNA binding domain
MCPNGMEK_00410 1e-212 I Diacylglycerol kinase catalytic domain
MCPNGMEK_00411 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
MCPNGMEK_00412 2.3e-240 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MCPNGMEK_00414 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
MCPNGMEK_00416 3.7e-96
MCPNGMEK_00417 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MCPNGMEK_00418 4.2e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
MCPNGMEK_00419 4.2e-144 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MCPNGMEK_00421 5.3e-278 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MCPNGMEK_00422 9.2e-126 degU K helix_turn_helix, Lux Regulon
MCPNGMEK_00423 1.5e-264 tcsS3 KT PspC domain
MCPNGMEK_00424 2.7e-300 pspC KT PspC domain
MCPNGMEK_00425 3.2e-130
MCPNGMEK_00426 1.5e-112 S Protein of unknown function (DUF4125)
MCPNGMEK_00427 0.0 S Domain of unknown function (DUF4037)
MCPNGMEK_00428 1.5e-217 araJ EGP Major facilitator Superfamily
MCPNGMEK_00430 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MCPNGMEK_00431 4.3e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MCPNGMEK_00432 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MCPNGMEK_00433 6.7e-09 EGP Major facilitator Superfamily
MCPNGMEK_00434 1.7e-117 phoU P Plays a role in the regulation of phosphate uptake
MCPNGMEK_00435 2e-217 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MCPNGMEK_00436 2.6e-39
MCPNGMEK_00437 1.7e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MCPNGMEK_00438 7.2e-181 usp 3.5.1.28 CBM50 S CHAP domain
MCPNGMEK_00439 2.4e-107 M NlpC/P60 family
MCPNGMEK_00440 9.2e-192 T Universal stress protein family
MCPNGMEK_00441 1e-72 attW O OsmC-like protein
MCPNGMEK_00442 1.6e-173 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MCPNGMEK_00443 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
MCPNGMEK_00444 2.1e-96 ptpA 3.1.3.48 T low molecular weight
MCPNGMEK_00445 2.2e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
MCPNGMEK_00446 2.2e-38 azlD E Branched-chain amino acid transport protein (AzlD)
MCPNGMEK_00447 9.9e-112 vex2 V ABC transporter, ATP-binding protein
MCPNGMEK_00448 3.2e-212 vex1 V Efflux ABC transporter, permease protein
MCPNGMEK_00449 4.7e-220 vex3 V ABC transporter permease
MCPNGMEK_00451 6.6e-172
MCPNGMEK_00452 7.4e-109 ytrE V ABC transporter
MCPNGMEK_00453 3.7e-120 V N-Acetylmuramoyl-L-alanine amidase
MCPNGMEK_00454 4.8e-101
MCPNGMEK_00455 3.9e-119 K Transcriptional regulatory protein, C terminal
MCPNGMEK_00456 4e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MCPNGMEK_00457 1e-183 lacR K Transcriptional regulator, LacI family
MCPNGMEK_00458 1.7e-90 nagA 3.5.1.25 G Amidohydrolase family
MCPNGMEK_00459 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MCPNGMEK_00460 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
MCPNGMEK_00461 1.6e-17 S Transcription factor WhiB
MCPNGMEK_00463 3.2e-155 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MCPNGMEK_00464 1.2e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MCPNGMEK_00465 3.3e-68 S Domain of unknown function (DUF4190)
MCPNGMEK_00468 6.2e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
MCPNGMEK_00469 1.9e-177 3.4.14.13 M Glycosyltransferase like family 2
MCPNGMEK_00470 1.5e-273 S AI-2E family transporter
MCPNGMEK_00471 1.3e-232 epsG M Glycosyl transferase family 21
MCPNGMEK_00472 1.7e-168 natA V ATPases associated with a variety of cellular activities
MCPNGMEK_00473 3.4e-310
MCPNGMEK_00474 2.8e-263 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
MCPNGMEK_00475 9.2e-214 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MCPNGMEK_00476 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MCPNGMEK_00477 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MCPNGMEK_00478 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
MCPNGMEK_00479 6.2e-165 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MCPNGMEK_00480 2.1e-293 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MCPNGMEK_00481 1.3e-77 S Protein of unknown function (DUF3180)
MCPNGMEK_00482 7.1e-172 tesB I Thioesterase-like superfamily
MCPNGMEK_00483 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
MCPNGMEK_00484 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
MCPNGMEK_00486 2.2e-168 M domain, Protein
MCPNGMEK_00487 2e-126
MCPNGMEK_00488 6.7e-116 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MCPNGMEK_00489 5.6e-40 S Protein of unknown function (DUF979)
MCPNGMEK_00490 2.2e-78 S DUF218 domain
MCPNGMEK_00492 3.6e-114 S Pyridoxamine 5'-phosphate oxidase
MCPNGMEK_00493 3.4e-160 I alpha/beta hydrolase fold
MCPNGMEK_00494 2.1e-55 EGP Major facilitator Superfamily
MCPNGMEK_00495 2.4e-300 S ATPases associated with a variety of cellular activities
MCPNGMEK_00496 3.7e-179 glkA 2.7.1.2 G ROK family
MCPNGMEK_00497 5.9e-77 EGP Major facilitator superfamily
MCPNGMEK_00498 4.9e-37 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
MCPNGMEK_00499 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
MCPNGMEK_00500 3.4e-216 MA20_36090 S Psort location Cytoplasmic, score 8.87
MCPNGMEK_00501 1.6e-28 L Transposase
MCPNGMEK_00503 1.8e-148 S Sulfite exporter TauE/SafE
MCPNGMEK_00504 1.6e-149 V FtsX-like permease family
MCPNGMEK_00506 4.2e-164 EG EamA-like transporter family
MCPNGMEK_00507 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
MCPNGMEK_00508 1.2e-141 3.5.2.6 V Beta-lactamase enzyme family
MCPNGMEK_00509 8.3e-170 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
MCPNGMEK_00510 1.5e-108
MCPNGMEK_00511 7.1e-258 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
MCPNGMEK_00512 5.2e-179 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MCPNGMEK_00513 2.6e-163 glcU G Sugar transport protein
MCPNGMEK_00514 6.9e-195 K helix_turn_helix, arabinose operon control protein
MCPNGMEK_00516 3.9e-36 rpmE J Binds the 23S rRNA
MCPNGMEK_00517 1.2e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MCPNGMEK_00518 3.1e-189 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MCPNGMEK_00519 1e-49 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
MCPNGMEK_00520 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
MCPNGMEK_00521 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
MCPNGMEK_00522 4.1e-289 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MCPNGMEK_00523 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MCPNGMEK_00524 3.1e-39 KT Transcriptional regulatory protein, C terminal
MCPNGMEK_00525 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MCPNGMEK_00526 8.2e-162 supH S Sucrose-6F-phosphate phosphohydrolase
MCPNGMEK_00527 2.9e-273 recD2 3.6.4.12 L PIF1-like helicase
MCPNGMEK_00528 2.5e-23 recD2 3.6.4.12 L PIF1-like helicase
MCPNGMEK_00529 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MCPNGMEK_00530 6.8e-86
MCPNGMEK_00531 1.6e-120 L Single-strand binding protein family
MCPNGMEK_00532 0.0 pepO 3.4.24.71 O Peptidase family M13
MCPNGMEK_00533 3.1e-127 S Short repeat of unknown function (DUF308)
MCPNGMEK_00534 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
MCPNGMEK_00535 3.8e-251 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
MCPNGMEK_00536 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
MCPNGMEK_00537 1.1e-197 yghZ C Aldo/keto reductase family
MCPNGMEK_00538 3e-56 racA K MerR, DNA binding
MCPNGMEK_00539 0.0 ctpE P E1-E2 ATPase
MCPNGMEK_00540 0.0 macB_2 V ATPases associated with a variety of cellular activities
MCPNGMEK_00541 2e-225 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MCPNGMEK_00542 2.1e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
MCPNGMEK_00543 4e-234 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MCPNGMEK_00544 1.5e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
MCPNGMEK_00545 5e-125 XK27_08050 O prohibitin homologues
MCPNGMEK_00546 3.1e-278 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
MCPNGMEK_00547 5e-55 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MCPNGMEK_00548 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MCPNGMEK_00550 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
MCPNGMEK_00551 1.4e-17 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MCPNGMEK_00552 5.5e-189 K Periplasmic binding protein domain
MCPNGMEK_00553 9e-127 G ABC transporter permease
MCPNGMEK_00554 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MCPNGMEK_00555 3.8e-66 G carbohydrate transport
MCPNGMEK_00556 4.4e-277 G Bacterial extracellular solute-binding protein
MCPNGMEK_00557 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MCPNGMEK_00558 2.3e-311 E ABC transporter, substrate-binding protein, family 5
MCPNGMEK_00559 1.4e-170 P Binding-protein-dependent transport system inner membrane component
MCPNGMEK_00560 2.1e-161 EP Binding-protein-dependent transport system inner membrane component
MCPNGMEK_00561 4e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
MCPNGMEK_00562 1.2e-155 sapF E ATPases associated with a variety of cellular activities
MCPNGMEK_00563 1.3e-190 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCPNGMEK_00564 9.9e-67 L Transposase and inactivated derivatives IS30 family
MCPNGMEK_00565 8.8e-259 S Domain of unknown function (DUF4143)
MCPNGMEK_00566 2e-17 yccF S Inner membrane component domain
MCPNGMEK_00567 3.5e-12
MCPNGMEK_00568 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
MCPNGMEK_00569 3.9e-43 tnp7109-21 L Integrase core domain
MCPNGMEK_00570 2.5e-52 L IstB-like ATP binding protein
MCPNGMEK_00571 8.7e-46 L Transposase
MCPNGMEK_00572 2e-73 I Sterol carrier protein
MCPNGMEK_00573 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MCPNGMEK_00574 3.4e-35
MCPNGMEK_00575 1.4e-144 gluP 3.4.21.105 S Rhomboid family
MCPNGMEK_00576 1.3e-120 L HTH-like domain
MCPNGMEK_00577 4.7e-257 L ribosomal rna small subunit methyltransferase
MCPNGMEK_00578 2.6e-71 crgA D Involved in cell division
MCPNGMEK_00579 2.7e-143 S Bacterial protein of unknown function (DUF881)
MCPNGMEK_00580 7.5e-233 srtA 3.4.22.70 M Sortase family
MCPNGMEK_00581 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
MCPNGMEK_00582 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
MCPNGMEK_00583 6.7e-184 T Protein tyrosine kinase
MCPNGMEK_00584 3.4e-264 pbpA M penicillin-binding protein
MCPNGMEK_00585 2.8e-266 rodA D Belongs to the SEDS family
MCPNGMEK_00586 9.7e-260 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
MCPNGMEK_00587 7.9e-94 fhaB T Inner membrane component of T3SS, cytoplasmic domain
MCPNGMEK_00588 1e-130 fhaA T Protein of unknown function (DUF2662)
MCPNGMEK_00589 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
MCPNGMEK_00590 0.0 pip S YhgE Pip domain protein
MCPNGMEK_00591 0.0 pip S YhgE Pip domain protein
MCPNGMEK_00592 1.9e-75 pldB 3.1.1.5 I Serine aminopeptidase, S33
MCPNGMEK_00593 2e-120 pldB 3.1.1.5 I Serine aminopeptidase, S33
MCPNGMEK_00594 7.4e-167 yicL EG EamA-like transporter family
MCPNGMEK_00595 3.7e-105
MCPNGMEK_00597 5.4e-197 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MCPNGMEK_00599 0.0 KL Domain of unknown function (DUF3427)
MCPNGMEK_00600 2.5e-89 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MCPNGMEK_00601 9.4e-44 D DivIVA domain protein
MCPNGMEK_00602 9.3e-53 ybjQ S Putative heavy-metal-binding
MCPNGMEK_00603 1.4e-158 I Serine aminopeptidase, S33
MCPNGMEK_00604 2e-85 yjcF Q Acetyltransferase (GNAT) domain
MCPNGMEK_00606 8.4e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MCPNGMEK_00607 1.3e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
MCPNGMEK_00608 0.0 cadA P E1-E2 ATPase
MCPNGMEK_00609 5e-273 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
MCPNGMEK_00610 4.8e-171 htpX O Belongs to the peptidase M48B family
MCPNGMEK_00612 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCPNGMEK_00613 1.9e-42 S Bacterial mobilisation protein (MobC)
MCPNGMEK_00614 2.3e-127 S Domain of unknown function (DUF4417)
MCPNGMEK_00616 1.9e-61
MCPNGMEK_00617 6.8e-65
MCPNGMEK_00618 3.9e-50 E IrrE N-terminal-like domain
MCPNGMEK_00619 2e-12 E IrrE N-terminal-like domain
MCPNGMEK_00620 4.9e-57 K Cro/C1-type HTH DNA-binding domain
MCPNGMEK_00621 1.1e-253 3.5.1.104 G Polysaccharide deacetylase
MCPNGMEK_00622 3.3e-200 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MCPNGMEK_00623 1.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MCPNGMEK_00624 5.1e-165 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCPNGMEK_00625 1.1e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCPNGMEK_00626 7.1e-200 K helix_turn _helix lactose operon repressor
MCPNGMEK_00627 2.8e-78 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
MCPNGMEK_00628 1.7e-296 scrT G Transporter major facilitator family protein
MCPNGMEK_00629 2.9e-254 yhjE EGP Sugar (and other) transporter
MCPNGMEK_00630 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MCPNGMEK_00631 8.2e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MCPNGMEK_00632 2.3e-184 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
MCPNGMEK_00633 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MCPNGMEK_00634 3.5e-277 aroP E aromatic amino acid transport protein AroP K03293
MCPNGMEK_00635 2.4e-101 K Transcriptional regulator C-terminal region
MCPNGMEK_00636 2.6e-129 V ABC transporter
MCPNGMEK_00637 0.0 V FtsX-like permease family
MCPNGMEK_00638 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MCPNGMEK_00639 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MCPNGMEK_00640 1.2e-39 E ABC transporter
MCPNGMEK_00641 7.6e-100 bcp 1.11.1.15 O Redoxin
MCPNGMEK_00642 1.7e-155 S Virulence factor BrkB
MCPNGMEK_00643 4.2e-42 XAC3035 O Glutaredoxin
MCPNGMEK_00644 1.6e-105 L Transposase
MCPNGMEK_00645 8.2e-22 L Transposase
MCPNGMEK_00646 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MCPNGMEK_00647 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MCPNGMEK_00648 5.5e-55 L HNH endonuclease
MCPNGMEK_00649 2.9e-243 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCPNGMEK_00650 4.9e-117
MCPNGMEK_00651 1.7e-266 EGP Major Facilitator Superfamily
MCPNGMEK_00652 8.4e-136 L Integrase core domain
MCPNGMEK_00653 1.7e-34 L Psort location Cytoplasmic, score 8.87
MCPNGMEK_00654 3e-113 K WHG domain
MCPNGMEK_00655 4.8e-73 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
MCPNGMEK_00657 7.9e-17 M Belongs to the glycosyl hydrolase 30 family
MCPNGMEK_00658 4e-100 M Belongs to the glycosyl hydrolase 30 family
MCPNGMEK_00660 3.3e-191 1.1.1.65 C Aldo/keto reductase family
MCPNGMEK_00661 5.9e-94 ydgJ K helix_turn_helix multiple antibiotic resistance protein
MCPNGMEK_00662 0.0 lmrA1 V ABC transporter, ATP-binding protein
MCPNGMEK_00663 0.0 lmrA2 V ABC transporter transmembrane region
MCPNGMEK_00664 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
MCPNGMEK_00665 1.3e-107 S Phosphatidylethanolamine-binding protein
MCPNGMEK_00666 0.0 pepD E Peptidase family C69
MCPNGMEK_00667 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
MCPNGMEK_00668 1.3e-62 S Macrophage migration inhibitory factor (MIF)
MCPNGMEK_00669 4e-98 S GtrA-like protein
MCPNGMEK_00670 6.2e-263 EGP Major facilitator Superfamily
MCPNGMEK_00671 1.1e-126 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
MCPNGMEK_00672 5.8e-145
MCPNGMEK_00673 1.7e-137 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
MCPNGMEK_00674 1.7e-201 P NMT1/THI5 like
MCPNGMEK_00675 3.1e-124 S HAD hydrolase, family IA, variant 3
MCPNGMEK_00677 6.3e-298 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MCPNGMEK_00678 8e-99 S Domain of unknown function (DUF4143)
MCPNGMEK_00679 3.5e-67 S Domain of unknown function (DUF4143)
MCPNGMEK_00682 6.8e-253 S Calcineurin-like phosphoesterase
MCPNGMEK_00683 2.2e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
MCPNGMEK_00684 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MCPNGMEK_00685 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MCPNGMEK_00686 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
MCPNGMEK_00688 2.4e-190 S CAAX protease self-immunity
MCPNGMEK_00689 3.6e-221 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
MCPNGMEK_00690 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MCPNGMEK_00691 7.4e-226 G Transmembrane secretion effector
MCPNGMEK_00692 8.7e-133 K Bacterial regulatory proteins, tetR family
MCPNGMEK_00693 3.5e-134
MCPNGMEK_00694 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MCPNGMEK_00695 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MCPNGMEK_00696 7.5e-167 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
MCPNGMEK_00697 5.8e-189
MCPNGMEK_00698 7.9e-180
MCPNGMEK_00699 1.3e-163 trxA2 O Tetratricopeptide repeat
MCPNGMEK_00700 8.8e-121 cyaA 4.6.1.1 S CYTH
MCPNGMEK_00702 4.8e-185 K Bacterial regulatory proteins, lacI family
MCPNGMEK_00703 5.9e-17 4.2.1.68 M carboxylic acid catabolic process
MCPNGMEK_00704 2.6e-85 4.2.1.68 M Enolase C-terminal domain-like
MCPNGMEK_00705 4.7e-20 IQ KR domain
MCPNGMEK_00706 1.8e-144 IQ KR domain
MCPNGMEK_00708 3.1e-286 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MCPNGMEK_00709 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
MCPNGMEK_00710 6.4e-179 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MCPNGMEK_00711 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MCPNGMEK_00712 1.1e-305 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MCPNGMEK_00713 2.1e-80 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MCPNGMEK_00714 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
MCPNGMEK_00715 2.3e-240 hom 1.1.1.3 E Homoserine dehydrogenase
MCPNGMEK_00716 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MCPNGMEK_00717 1.1e-280 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
MCPNGMEK_00718 9.9e-67
MCPNGMEK_00719 6.1e-58
MCPNGMEK_00720 4.9e-165 V ATPases associated with a variety of cellular activities
MCPNGMEK_00721 3.3e-256 V Efflux ABC transporter, permease protein
MCPNGMEK_00722 2.2e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
MCPNGMEK_00723 1.7e-240 dapE 3.5.1.18 E Peptidase dimerisation domain
MCPNGMEK_00724 0.0 rne 3.1.26.12 J Ribonuclease E/G family
MCPNGMEK_00725 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
MCPNGMEK_00726 3.1e-40 rpmA J Ribosomal L27 protein
MCPNGMEK_00727 7.5e-216 K Psort location Cytoplasmic, score
MCPNGMEK_00728 3.7e-299 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MCPNGMEK_00729 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MCPNGMEK_00730 4e-231 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
MCPNGMEK_00732 4.7e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MCPNGMEK_00733 2.1e-117 nusG K Participates in transcription elongation, termination and antitermination
MCPNGMEK_00734 2.8e-173 plsC2 2.3.1.51 I Phosphate acyltransferases
MCPNGMEK_00735 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MCPNGMEK_00736 8.8e-220 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MCPNGMEK_00737 2e-202 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MCPNGMEK_00738 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
MCPNGMEK_00739 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MCPNGMEK_00740 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MCPNGMEK_00741 1.5e-119
MCPNGMEK_00742 4.3e-163 T Pfam Adenylate and Guanylate cyclase catalytic domain
MCPNGMEK_00743 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MCPNGMEK_00744 1.1e-79 ssb1 L Single-stranded DNA-binding protein
MCPNGMEK_00745 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MCPNGMEK_00746 3.8e-70 rplI J Binds to the 23S rRNA
MCPNGMEK_00747 2.4e-16 S Parallel beta-helix repeats
MCPNGMEK_00748 4.1e-48 S Parallel beta-helix repeats
MCPNGMEK_00749 1e-69 E Domain of unknown function (DUF5011)
MCPNGMEK_00751 3.7e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MCPNGMEK_00752 1.3e-129 M Protein of unknown function (DUF3152)
MCPNGMEK_00753 1.4e-186 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCPNGMEK_00754 2.2e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MCPNGMEK_00755 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
MCPNGMEK_00756 0.0 inlJ M domain protein
MCPNGMEK_00757 1.2e-291 M LPXTG cell wall anchor motif
MCPNGMEK_00758 1e-215 3.4.22.70 M Sortase family
MCPNGMEK_00759 1.6e-66 S Domain of unknown function (DUF4854)
MCPNGMEK_00760 3.8e-156 fahA Q Fumarylacetoacetate (FAA) hydrolase family
MCPNGMEK_00761 8.7e-31 2.1.1.72 S Protein conserved in bacteria
MCPNGMEK_00762 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MCPNGMEK_00763 1.6e-132 M Mechanosensitive ion channel
MCPNGMEK_00764 1.3e-119 K Bacterial regulatory proteins, tetR family
MCPNGMEK_00765 5.4e-242 MA20_36090 S Psort location Cytoplasmic, score 8.87
MCPNGMEK_00766 4.2e-233 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
MCPNGMEK_00767 3.4e-81
MCPNGMEK_00768 1.5e-22 M Belongs to the glycosyl hydrolase 28 family
MCPNGMEK_00770 4.5e-45 K Transcriptional regulator
MCPNGMEK_00771 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MCPNGMEK_00772 3.5e-07 S Scramblase
MCPNGMEK_00773 3.9e-37
MCPNGMEK_00778 1.9e-146 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
MCPNGMEK_00779 3e-237 K Helix-turn-helix XRE-family like proteins
MCPNGMEK_00780 3.7e-54 relB L RelB antitoxin
MCPNGMEK_00781 2.6e-17 T Toxic component of a toxin-antitoxin (TA) module
MCPNGMEK_00782 2e-132 K helix_turn_helix, mercury resistance
MCPNGMEK_00783 2.3e-243 yxiO S Vacuole effluxer Atg22 like
MCPNGMEK_00785 6.5e-201 yegV G pfkB family carbohydrate kinase
MCPNGMEK_00786 1.4e-29 rpmB J Ribosomal L28 family
MCPNGMEK_00787 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
MCPNGMEK_00788 1.2e-220 steT E amino acid
MCPNGMEK_00791 0.0
MCPNGMEK_00792 2.9e-229 U Sodium:dicarboxylate symporter family
MCPNGMEK_00793 8.9e-122 rsmD 2.1.1.171 L Conserved hypothetical protein 95
MCPNGMEK_00794 1.4e-107 XK27_02070 S Nitroreductase family
MCPNGMEK_00795 6.8e-83 hsp20 O Hsp20/alpha crystallin family
MCPNGMEK_00796 1.4e-165 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MCPNGMEK_00797 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MCPNGMEK_00798 1.8e-34 CP_0960 S Belongs to the UPF0109 family
MCPNGMEK_00799 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MCPNGMEK_00800 1e-295 ydfD EK Alanine-glyoxylate amino-transferase
MCPNGMEK_00801 5.9e-94 argO S LysE type translocator
MCPNGMEK_00802 2.8e-221 S Endonuclease/Exonuclease/phosphatase family
MCPNGMEK_00803 8.4e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MCPNGMEK_00804 1.4e-164 P Cation efflux family
MCPNGMEK_00805 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCPNGMEK_00806 2.3e-136 guaA1 6.3.5.2 F Peptidase C26
MCPNGMEK_00807 0.0 yjjK S ABC transporter
MCPNGMEK_00808 2e-58 S Protein of unknown function (DUF3039)
MCPNGMEK_00809 1.4e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MCPNGMEK_00810 5.5e-108
MCPNGMEK_00811 1e-113 yceD S Uncharacterized ACR, COG1399
MCPNGMEK_00812 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MCPNGMEK_00813 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MCPNGMEK_00814 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
MCPNGMEK_00815 7.6e-92 ilvN 2.2.1.6 E ACT domain
MCPNGMEK_00817 7.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MCPNGMEK_00818 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MCPNGMEK_00819 1.7e-117 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MCPNGMEK_00820 2.4e-176 S Auxin Efflux Carrier
MCPNGMEK_00823 0.0 pgi 5.3.1.9 G Belongs to the GPI family
MCPNGMEK_00824 1.5e-190
MCPNGMEK_00826 6.9e-201
MCPNGMEK_00828 5.5e-122 mgtC S MgtC family
MCPNGMEK_00829 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
MCPNGMEK_00830 3.2e-278 abcT3 P ATPases associated with a variety of cellular activities
MCPNGMEK_00831 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
MCPNGMEK_00833 1.4e-173 K Putative sugar-binding domain
MCPNGMEK_00834 4e-213 gatC G PTS system sugar-specific permease component
MCPNGMEK_00835 1e-295 2.7.1.53 G FGGY family of carbohydrate kinases, C-terminal domain
MCPNGMEK_00836 1.1e-172 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
MCPNGMEK_00837 1.1e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
MCPNGMEK_00838 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MCPNGMEK_00839 1.8e-158 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MCPNGMEK_00840 4.2e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCPNGMEK_00841 1.5e-208 K helix_turn _helix lactose operon repressor
MCPNGMEK_00842 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MCPNGMEK_00843 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MCPNGMEK_00844 1.3e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MCPNGMEK_00847 2.3e-308 G Glycosyl hydrolases family 43
MCPNGMEK_00848 3.6e-200 K helix_turn _helix lactose operon repressor
MCPNGMEK_00849 9.7e-11 E Domain of unknown function (DUF5011)
MCPNGMEK_00850 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
MCPNGMEK_00851 2.1e-134 L Protein of unknown function (DUF1524)
MCPNGMEK_00852 1.9e-226 mntH P H( )-stimulated, divalent metal cation uptake system
MCPNGMEK_00853 1.8e-306 EGP Major facilitator Superfamily
MCPNGMEK_00854 5.7e-241
MCPNGMEK_00855 3.9e-179 S G5
MCPNGMEK_00856 2.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
MCPNGMEK_00857 2.8e-119 F Domain of unknown function (DUF4916)
MCPNGMEK_00858 1.4e-161 mhpC I Alpha/beta hydrolase family
MCPNGMEK_00859 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MCPNGMEK_00860 0.0 enhA_2 S L,D-transpeptidase catalytic domain
MCPNGMEK_00861 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MCPNGMEK_00862 1.1e-240 S Uncharacterized conserved protein (DUF2183)
MCPNGMEK_00863 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
MCPNGMEK_00864 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MCPNGMEK_00865 9.9e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
MCPNGMEK_00866 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
MCPNGMEK_00867 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MCPNGMEK_00868 6.7e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
MCPNGMEK_00869 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MCPNGMEK_00870 3.1e-139 glpR K DeoR C terminal sensor domain
MCPNGMEK_00871 3.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
MCPNGMEK_00872 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
MCPNGMEK_00873 5e-243 EGP Sugar (and other) transporter
MCPNGMEK_00874 4.2e-43 gcvR T Belongs to the UPF0237 family
MCPNGMEK_00875 7.2e-253 S UPF0210 protein
MCPNGMEK_00876 7.5e-135
MCPNGMEK_00878 6.3e-122 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MCPNGMEK_00879 1.5e-07 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
MCPNGMEK_00880 5.9e-52 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
MCPNGMEK_00881 3e-35 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
MCPNGMEK_00882 3e-184 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
MCPNGMEK_00883 3.3e-110
MCPNGMEK_00884 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCPNGMEK_00885 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCPNGMEK_00886 1.3e-96 T Forkhead associated domain
MCPNGMEK_00887 1.1e-67 B Belongs to the OprB family
MCPNGMEK_00888 2e-166 3.1.3.16 T Sigma factor PP2C-like phosphatases
MCPNGMEK_00889 0.0 E Transglutaminase-like superfamily
MCPNGMEK_00890 4.6e-228 S Protein of unknown function DUF58
MCPNGMEK_00891 1.8e-232 S ATPase family associated with various cellular activities (AAA)
MCPNGMEK_00892 0.0 S Fibronectin type 3 domain
MCPNGMEK_00893 2.3e-270 KLT Protein tyrosine kinase
MCPNGMEK_00894 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
MCPNGMEK_00895 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
MCPNGMEK_00896 6.2e-157 K -acetyltransferase
MCPNGMEK_00897 5.5e-256 G Major Facilitator Superfamily
MCPNGMEK_00898 1.2e-67 gsiA P ATPase activity
MCPNGMEK_00899 6.5e-43 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MCPNGMEK_00900 6.4e-24 relB L RelB antitoxin
MCPNGMEK_00901 2.3e-59 L Transposase
MCPNGMEK_00902 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MCPNGMEK_00903 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MCPNGMEK_00904 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MCPNGMEK_00905 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
MCPNGMEK_00906 2.1e-294 O Subtilase family
MCPNGMEK_00907 1.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MCPNGMEK_00908 8.8e-124 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MCPNGMEK_00909 2.7e-271 S zinc finger
MCPNGMEK_00910 2.7e-95 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MCPNGMEK_00911 2.9e-229 aspB E Aminotransferase class-V
MCPNGMEK_00912 7.6e-49 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MCPNGMEK_00913 5.4e-133 tmp1 S Domain of unknown function (DUF4391)
MCPNGMEK_00914 2.6e-149 moeB 2.7.7.80 H ThiF family
MCPNGMEK_00915 7.5e-258 cdr OP Sulfurtransferase TusA
MCPNGMEK_00916 2.8e-182 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MCPNGMEK_00919 5e-173 S Endonuclease/Exonuclease/phosphatase family
MCPNGMEK_00920 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCPNGMEK_00921 2.7e-271 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCPNGMEK_00922 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
MCPNGMEK_00923 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MCPNGMEK_00924 1.1e-27 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MCPNGMEK_00925 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
MCPNGMEK_00926 1.2e-166
MCPNGMEK_00927 9.1e-258 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
MCPNGMEK_00928 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
MCPNGMEK_00930 1.1e-90 K MarR family
MCPNGMEK_00931 0.0 V ABC transporter, ATP-binding protein
MCPNGMEK_00932 0.0 V ABC transporter transmembrane region
MCPNGMEK_00933 8.8e-168 S Patatin-like phospholipase
MCPNGMEK_00934 4.6e-154 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MCPNGMEK_00935 2.3e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MCPNGMEK_00936 2e-115 S Vitamin K epoxide reductase
MCPNGMEK_00937 3.9e-167 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
MCPNGMEK_00938 2.7e-237 mphA S Aminoglycoside phosphotransferase
MCPNGMEK_00939 9.6e-283 uvrD2 3.6.4.12 L DNA helicase
MCPNGMEK_00940 6.6e-279 S Zincin-like metallopeptidase
MCPNGMEK_00941 1.2e-152 lon T Belongs to the peptidase S16 family
MCPNGMEK_00942 5.7e-47 S Protein of unknown function (DUF3052)
MCPNGMEK_00943 1.2e-196 K helix_turn _helix lactose operon repressor
MCPNGMEK_00944 1.2e-61 S Thiamine-binding protein
MCPNGMEK_00945 1.8e-164 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MCPNGMEK_00946 6.9e-231 O AAA domain (Cdc48 subfamily)
MCPNGMEK_00947 1.3e-84
MCPNGMEK_00948 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MCPNGMEK_00949 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MCPNGMEK_00950 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
MCPNGMEK_00951 1e-248 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MCPNGMEK_00952 9.5e-247 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MCPNGMEK_00953 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MCPNGMEK_00954 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MCPNGMEK_00955 2.1e-42 yggT S YGGT family
MCPNGMEK_00956 9.7e-90 3.1.21.3 V DivIVA protein
MCPNGMEK_00957 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MCPNGMEK_00958 9e-178 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MCPNGMEK_00960 6e-63
MCPNGMEK_00961 2.6e-138 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MCPNGMEK_00962 3.7e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MCPNGMEK_00963 8.7e-201 ftsE D Cell division ATP-binding protein FtsE
MCPNGMEK_00964 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
MCPNGMEK_00965 4.6e-168 usp 3.5.1.28 CBM50 D CHAP domain protein
MCPNGMEK_00966 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MCPNGMEK_00967 3e-147 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
MCPNGMEK_00968 3.3e-23
MCPNGMEK_00970 6.9e-207 2.7.11.1 NU Tfp pilus assembly protein FimV
MCPNGMEK_00971 5.2e-223 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MCPNGMEK_00972 4.7e-236 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MCPNGMEK_00973 1.4e-292 I acetylesterase activity
MCPNGMEK_00974 9.2e-144 recO L Involved in DNA repair and RecF pathway recombination
MCPNGMEK_00975 1.8e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MCPNGMEK_00976 4.3e-191 ywqG S Domain of unknown function (DUF1963)
MCPNGMEK_00977 6.5e-15 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MCPNGMEK_00978 3e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MCPNGMEK_00979 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
MCPNGMEK_00980 3.4e-106 S zinc-ribbon domain
MCPNGMEK_00981 1.6e-46 yhbY J CRS1_YhbY
MCPNGMEK_00982 0.0 4.2.1.53 S MCRA family
MCPNGMEK_00985 1.2e-202 K WYL domain
MCPNGMEK_00986 1.3e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
MCPNGMEK_00987 2.4e-172 dkgA 1.1.1.346 C Aldo/keto reductase family
MCPNGMEK_00988 9.9e-76 yneG S Domain of unknown function (DUF4186)
MCPNGMEK_00991 5.1e-184 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCPNGMEK_00992 1.1e-256 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MCPNGMEK_00993 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MCPNGMEK_00994 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
MCPNGMEK_00995 5.9e-113
MCPNGMEK_00996 4.8e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MCPNGMEK_00997 1.7e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
MCPNGMEK_00998 4.9e-284 S Uncharacterized protein conserved in bacteria (DUF2252)
MCPNGMEK_00999 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
MCPNGMEK_01000 5.9e-255 S Domain of unknown function (DUF5067)
MCPNGMEK_01001 1e-60 EGP Major facilitator Superfamily
MCPNGMEK_01002 1.3e-172 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MCPNGMEK_01003 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
MCPNGMEK_01004 1.4e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
MCPNGMEK_01005 3.9e-173
MCPNGMEK_01006 3.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MCPNGMEK_01007 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
MCPNGMEK_01008 1.2e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MCPNGMEK_01009 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MCPNGMEK_01010 1.7e-50 M Lysin motif
MCPNGMEK_01011 2.3e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MCPNGMEK_01012 1.7e-229 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MCPNGMEK_01013 0.0 L DNA helicase
MCPNGMEK_01014 1.3e-90 mraZ K Belongs to the MraZ family
MCPNGMEK_01015 1.6e-205 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MCPNGMEK_01016 9.7e-64 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MCPNGMEK_01017 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
MCPNGMEK_01018 2.8e-180 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MCPNGMEK_01019 4.1e-284 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MCPNGMEK_01020 3.6e-202 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MCPNGMEK_01021 1.2e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MCPNGMEK_01022 2.4e-221 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
MCPNGMEK_01023 1.7e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MCPNGMEK_01024 1.6e-296 murC 6.3.2.8 M Belongs to the MurCDEF family
MCPNGMEK_01025 2e-156 ftsQ 6.3.2.4 D Cell division protein FtsQ
MCPNGMEK_01026 1.3e-37
MCPNGMEK_01028 1e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MCPNGMEK_01029 1.5e-236 G Major Facilitator Superfamily
MCPNGMEK_01030 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
MCPNGMEK_01031 1.3e-224 GK ROK family
MCPNGMEK_01032 3.4e-132 cutC P Participates in the control of copper homeostasis
MCPNGMEK_01033 7e-217 GK ROK family
MCPNGMEK_01034 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MCPNGMEK_01035 7.4e-244 nagA 3.5.1.25 G Amidohydrolase family
MCPNGMEK_01036 1.5e-305 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
MCPNGMEK_01037 3e-185 dppB EP Binding-protein-dependent transport system inner membrane component
MCPNGMEK_01038 5.1e-191 dppC EP Binding-protein-dependent transport system inner membrane component
MCPNGMEK_01039 0.0 P Belongs to the ABC transporter superfamily
MCPNGMEK_01040 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
MCPNGMEK_01041 4.3e-97 3.6.1.55 F NUDIX domain
MCPNGMEK_01043 4.7e-283 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
MCPNGMEK_01044 0.0 smc D Required for chromosome condensation and partitioning
MCPNGMEK_01045 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
MCPNGMEK_01046 5.5e-244 yxbA 6.3.1.12 S ATP-grasp
MCPNGMEK_01047 3.1e-231 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
MCPNGMEK_01048 6.8e-192 V Acetyltransferase (GNAT) domain
MCPNGMEK_01049 4.2e-297 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MCPNGMEK_01050 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
MCPNGMEK_01051 2e-64
MCPNGMEK_01052 1.4e-194 galM 5.1.3.3 G Aldose 1-epimerase
MCPNGMEK_01053 1.6e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MCPNGMEK_01055 7.1e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MCPNGMEK_01056 3.6e-199 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MCPNGMEK_01057 2.1e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
MCPNGMEK_01058 7.1e-68 S Spermine/spermidine synthase domain
MCPNGMEK_01059 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MCPNGMEK_01060 2.1e-25 rpmI J Ribosomal protein L35
MCPNGMEK_01061 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MCPNGMEK_01062 3.4e-180 xerD D recombinase XerD
MCPNGMEK_01063 1.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MCPNGMEK_01064 1.4e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MCPNGMEK_01065 3.4e-115 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MCPNGMEK_01066 8.6e-150 nrtR 3.6.1.55 F NUDIX hydrolase
MCPNGMEK_01067 7.5e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MCPNGMEK_01068 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MCPNGMEK_01069 1.4e-164 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
MCPNGMEK_01070 8e-238 iscS1 2.8.1.7 E Aminotransferase class-V
MCPNGMEK_01071 0.0 typA T Elongation factor G C-terminus
MCPNGMEK_01072 9.9e-81
MCPNGMEK_01073 3.5e-199 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
MCPNGMEK_01074 3.7e-193 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
MCPNGMEK_01075 7.3e-42
MCPNGMEK_01076 1.3e-187 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MCPNGMEK_01077 7.9e-177 appB EP Binding-protein-dependent transport system inner membrane component
MCPNGMEK_01078 3.5e-166 dppC EP N-terminal TM domain of oligopeptide transport permease C
MCPNGMEK_01079 0.0 oppD P Belongs to the ABC transporter superfamily
MCPNGMEK_01080 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
MCPNGMEK_01081 8.2e-276 pepC 3.4.22.40 E Peptidase C1-like family
MCPNGMEK_01082 1.3e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
MCPNGMEK_01083 3.2e-139 S Protein of unknown function (DUF3710)
MCPNGMEK_01084 1.7e-129 S Protein of unknown function (DUF3159)
MCPNGMEK_01085 4.5e-249 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MCPNGMEK_01086 2.3e-110
MCPNGMEK_01087 0.0 ctpE P E1-E2 ATPase
MCPNGMEK_01088 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MCPNGMEK_01090 1.8e-175 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCPNGMEK_01091 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
MCPNGMEK_01092 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MCPNGMEK_01093 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MCPNGMEK_01094 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MCPNGMEK_01096 3.2e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MCPNGMEK_01097 4.3e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MCPNGMEK_01098 5e-139 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
MCPNGMEK_01100 0.0 arc O AAA ATPase forming ring-shaped complexes
MCPNGMEK_01101 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
MCPNGMEK_01102 2.4e-158 hisN 3.1.3.25 G Inositol monophosphatase family
MCPNGMEK_01103 1.6e-10 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MCPNGMEK_01104 9e-278 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MCPNGMEK_01105 8.1e-42 hup L Belongs to the bacterial histone-like protein family
MCPNGMEK_01106 0.0 S Lysylphosphatidylglycerol synthase TM region
MCPNGMEK_01107 5e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
MCPNGMEK_01108 1.5e-291 S PGAP1-like protein
MCPNGMEK_01110 7.2e-75
MCPNGMEK_01111 1.6e-148 S von Willebrand factor (vWF) type A domain
MCPNGMEK_01112 2.3e-190 S von Willebrand factor (vWF) type A domain
MCPNGMEK_01113 6.4e-94
MCPNGMEK_01114 2.1e-177 S Protein of unknown function DUF58
MCPNGMEK_01115 5e-196 moxR S ATPase family associated with various cellular activities (AAA)
MCPNGMEK_01116 8e-145 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MCPNGMEK_01117 3.4e-71 S LytR cell envelope-related transcriptional attenuator
MCPNGMEK_01118 2.2e-44 cspA K 'Cold-shock' DNA-binding domain
MCPNGMEK_01119 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MCPNGMEK_01120 1.7e-10 S Proteins of 100 residues with WXG
MCPNGMEK_01121 7.6e-163
MCPNGMEK_01122 1.6e-134 KT Response regulator receiver domain protein
MCPNGMEK_01123 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MCPNGMEK_01124 1e-66 cspB K 'Cold-shock' DNA-binding domain
MCPNGMEK_01125 8.3e-204 S Protein of unknown function (DUF3027)
MCPNGMEK_01126 5.2e-184 uspA T Belongs to the universal stress protein A family
MCPNGMEK_01127 0.0 clpC O ATPase family associated with various cellular activities (AAA)
MCPNGMEK_01131 5.1e-217 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
MCPNGMEK_01132 2.4e-264 hisS 6.1.1.21 J Histidyl-tRNA synthetase
MCPNGMEK_01133 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MCPNGMEK_01134 7.4e-86 K helix_turn_helix, Lux Regulon
MCPNGMEK_01135 8.2e-93 S Aminoacyl-tRNA editing domain
MCPNGMEK_01136 3.6e-140 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
MCPNGMEK_01137 1.9e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
MCPNGMEK_01138 1.4e-111 gluC E Binding-protein-dependent transport system inner membrane component
MCPNGMEK_01139 3.7e-199 gluD E Binding-protein-dependent transport system inner membrane component
MCPNGMEK_01140 1.9e-192 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
MCPNGMEK_01141 0.0 L DEAD DEAH box helicase
MCPNGMEK_01142 7.7e-258 rarA L Recombination factor protein RarA
MCPNGMEK_01144 5.2e-257 EGP Major facilitator Superfamily
MCPNGMEK_01145 0.0 ecfA GP ABC transporter, ATP-binding protein
MCPNGMEK_01146 1.1e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MCPNGMEK_01148 1.3e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
MCPNGMEK_01149 2e-213 E Aminotransferase class I and II
MCPNGMEK_01150 6.2e-140 bioM P ATPases associated with a variety of cellular activities
MCPNGMEK_01151 1.6e-78 2.8.2.22 S Arylsulfotransferase Ig-like domain
MCPNGMEK_01152 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MCPNGMEK_01153 0.0 S Tetratricopeptide repeat
MCPNGMEK_01154 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MCPNGMEK_01155 8.1e-210 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MCPNGMEK_01156 2.3e-161 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
MCPNGMEK_01157 2.5e-247 int L Phage integrase, N-terminal SAM-like domain
MCPNGMEK_01160 7.5e-241 L Helix-turn-helix domain
MCPNGMEK_01161 1.7e-217 2.1.1.72 H Adenine-specific methyltransferase EcoRI
MCPNGMEK_01162 1.6e-46 KLT Protein tyrosine kinase
MCPNGMEK_01163 1.7e-09
MCPNGMEK_01164 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MCPNGMEK_01165 8.5e-306 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
MCPNGMEK_01166 2.4e-161
MCPNGMEK_01167 2.9e-229 3.1.21.3 V I restriction modification system specificity determinant
MCPNGMEK_01168 1e-57 cas3 L CRISPR system CASCADE complex protein CasA
MCPNGMEK_01169 8.2e-41
MCPNGMEK_01170 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
MCPNGMEK_01171 1.6e-143 S Domain of unknown function (DUF4191)
MCPNGMEK_01172 5.6e-283 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MCPNGMEK_01173 5.5e-104 S Protein of unknown function (DUF3043)
MCPNGMEK_01174 1.4e-259 argE E Peptidase dimerisation domain
MCPNGMEK_01175 3.4e-192 V N-Acetylmuramoyl-L-alanine amidase
MCPNGMEK_01176 1.9e-152 ytrE V ATPases associated with a variety of cellular activities
MCPNGMEK_01177 1.6e-199
MCPNGMEK_01178 2.3e-232 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
MCPNGMEK_01179 0.0 S Uncharacterised protein family (UPF0182)
MCPNGMEK_01180 9.6e-208 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MCPNGMEK_01181 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MCPNGMEK_01182 2.4e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
MCPNGMEK_01185 6.3e-131 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MCPNGMEK_01186 1.9e-197 GM GDP-mannose 4,6 dehydratase
MCPNGMEK_01187 3.6e-151 GM ABC-2 type transporter
MCPNGMEK_01188 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
MCPNGMEK_01189 2.7e-97 2.3.1.183 M Acetyltransferase (GNAT) domain
MCPNGMEK_01190 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MCPNGMEK_01191 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MCPNGMEK_01192 3.8e-279 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
MCPNGMEK_01193 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
MCPNGMEK_01194 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MCPNGMEK_01195 2.5e-101 divIC D Septum formation initiator
MCPNGMEK_01196 2e-106 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
MCPNGMEK_01197 4e-184 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MCPNGMEK_01199 1.6e-97
MCPNGMEK_01200 1.4e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
MCPNGMEK_01201 5.7e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
MCPNGMEK_01202 7.5e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MCPNGMEK_01204 2e-142 yplQ S Haemolysin-III related
MCPNGMEK_01205 7.2e-286 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MCPNGMEK_01206 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MCPNGMEK_01207 0.0 D FtsK/SpoIIIE family
MCPNGMEK_01208 4.9e-271 K Cell envelope-related transcriptional attenuator domain
MCPNGMEK_01209 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MCPNGMEK_01210 0.0 S Glycosyl transferase, family 2
MCPNGMEK_01211 5.7e-267
MCPNGMEK_01212 2.2e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
MCPNGMEK_01213 1e-156 cof 5.2.1.8 T Eukaryotic phosphomannomutase
MCPNGMEK_01214 7.7e-129 ctsW S Phosphoribosyl transferase domain
MCPNGMEK_01215 3.6e-72 rulA 3.4.21.88 KT Peptidase S24-like
MCPNGMEK_01216 4.3e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MCPNGMEK_01217 1.9e-127 T Response regulator receiver domain protein
MCPNGMEK_01218 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MCPNGMEK_01219 5.1e-102 carD K CarD-like/TRCF domain
MCPNGMEK_01220 8.5e-84 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MCPNGMEK_01221 4.3e-139 znuB U ABC 3 transport family
MCPNGMEK_01222 2.8e-165 znuC P ATPases associated with a variety of cellular activities
MCPNGMEK_01223 1.5e-173 P Zinc-uptake complex component A periplasmic
MCPNGMEK_01224 1.8e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MCPNGMEK_01225 3.3e-243 rpsA J Ribosomal protein S1
MCPNGMEK_01226 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MCPNGMEK_01227 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MCPNGMEK_01228 1.7e-179 terC P Integral membrane protein, TerC family
MCPNGMEK_01229 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
MCPNGMEK_01230 1.8e-110 aspA 3.6.1.13 L NUDIX domain
MCPNGMEK_01232 9.2e-120 pdtaR T Response regulator receiver domain protein
MCPNGMEK_01233 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MCPNGMEK_01234 2.9e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
MCPNGMEK_01235 2.5e-127 3.6.1.13 L NUDIX domain
MCPNGMEK_01236 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MCPNGMEK_01237 3.2e-220 ykiI
MCPNGMEK_01239 2.5e-14
MCPNGMEK_01240 5.6e-43 yafP 5.3.1.16 K Acetyltransferase (GNAT) domain
MCPNGMEK_01241 4.8e-24 yafP 5.3.1.16 K Acetyltransferase (GNAT) domain
MCPNGMEK_01242 5.3e-17 U Major Facilitator Superfamily
MCPNGMEK_01243 1.6e-73 K helix_turn_helix multiple antibiotic resistance protein
MCPNGMEK_01244 7.4e-73 K helix_turn_helix, mercury resistance
MCPNGMEK_01245 2e-163 1.1.1.346 S Aldo/keto reductase family
MCPNGMEK_01246 1.2e-100 3.5.1.124 S DJ-1/PfpI family
MCPNGMEK_01247 7.4e-129
MCPNGMEK_01249 9.6e-112 3.4.13.21 E Peptidase family S51
MCPNGMEK_01250 1.2e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MCPNGMEK_01251 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MCPNGMEK_01252 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MCPNGMEK_01253 1e-281 XK27_07020 S Domain of unknown function (DUF1846)
MCPNGMEK_01254 4.9e-60
MCPNGMEK_01256 9.9e-112 ysdA S Protein of unknown function (DUF1294)
MCPNGMEK_01257 1.2e-27
MCPNGMEK_01258 4.4e-51
MCPNGMEK_01260 3e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MCPNGMEK_01261 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MCPNGMEK_01262 1.7e-188 pit P Phosphate transporter family
MCPNGMEK_01263 1.1e-115 MA20_27875 P Protein of unknown function DUF47
MCPNGMEK_01264 1.1e-121 K helix_turn_helix, Lux Regulon
MCPNGMEK_01265 2e-236 T Histidine kinase
MCPNGMEK_01266 4e-43 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MCPNGMEK_01267 2e-188 V ATPases associated with a variety of cellular activities
MCPNGMEK_01268 8.1e-227 V ABC-2 family transporter protein
MCPNGMEK_01269 9e-254 V ABC-2 family transporter protein
MCPNGMEK_01270 2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MCPNGMEK_01271 7.6e-67 L Transposase and inactivated derivatives IS30 family
MCPNGMEK_01273 3.1e-107
MCPNGMEK_01274 1.2e-64 D MobA/MobL family
MCPNGMEK_01275 8.6e-48 L Transposase
MCPNGMEK_01276 5.9e-182 tnp7109-21 L Integrase core domain
MCPNGMEK_01277 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
MCPNGMEK_01278 2.4e-40
MCPNGMEK_01279 5.6e-112 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
MCPNGMEK_01281 1.7e-108 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MCPNGMEK_01282 2e-45 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MCPNGMEK_01284 2.2e-241 pbuX F Permease family
MCPNGMEK_01285 3e-107 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MCPNGMEK_01286 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
MCPNGMEK_01287 0.0 pcrA 3.6.4.12 L DNA helicase
MCPNGMEK_01288 4.8e-64 S Domain of unknown function (DUF4418)
MCPNGMEK_01289 3.8e-213 V FtsX-like permease family
MCPNGMEK_01290 1.9e-128 lolD V ABC transporter
MCPNGMEK_01291 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MCPNGMEK_01292 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
MCPNGMEK_01293 6.5e-136 pgm3 G Phosphoglycerate mutase family
MCPNGMEK_01294 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
MCPNGMEK_01295 1.1e-36
MCPNGMEK_01296 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MCPNGMEK_01297 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MCPNGMEK_01298 4.1e-188 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MCPNGMEK_01299 2e-48 3.4.23.43 S Type IV leader peptidase family
MCPNGMEK_01300 1.2e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MCPNGMEK_01301 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MCPNGMEK_01302 4.5e-79 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MCPNGMEK_01303 1.9e-75
MCPNGMEK_01304 1.7e-120 K helix_turn_helix, Lux Regulon
MCPNGMEK_01305 2.6e-07 3.4.22.70 M Sortase family
MCPNGMEK_01306 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MCPNGMEK_01307 3.6e-290 sufB O FeS assembly protein SufB
MCPNGMEK_01308 1.4e-234 sufD O FeS assembly protein SufD
MCPNGMEK_01309 1.4e-144 sufC O FeS assembly ATPase SufC
MCPNGMEK_01310 4.1e-242 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MCPNGMEK_01311 1.5e-100 iscU C SUF system FeS assembly protein, NifU family
MCPNGMEK_01312 1.2e-108 yitW S Iron-sulfur cluster assembly protein
MCPNGMEK_01313 4.7e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MCPNGMEK_01314 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
MCPNGMEK_01316 7.2e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MCPNGMEK_01317 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
MCPNGMEK_01318 3.4e-197 phoH T PhoH-like protein
MCPNGMEK_01319 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MCPNGMEK_01320 2.4e-251 corC S CBS domain
MCPNGMEK_01321 1.5e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MCPNGMEK_01322 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MCPNGMEK_01323 1.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
MCPNGMEK_01324 5.7e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
MCPNGMEK_01325 2.3e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MCPNGMEK_01326 4.4e-191 S alpha beta
MCPNGMEK_01327 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MCPNGMEK_01328 1.8e-225 ilvE 2.6.1.42 E Amino-transferase class IV
MCPNGMEK_01329 1.8e-46 S phosphoesterase or phosphohydrolase
MCPNGMEK_01330 1.3e-144 3.1.4.37 T RNA ligase
MCPNGMEK_01331 1.2e-135 S UPF0126 domain
MCPNGMEK_01332 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
MCPNGMEK_01333 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MCPNGMEK_01334 1.8e-246 hemN H Involved in the biosynthesis of porphyrin-containing compound
MCPNGMEK_01335 3.4e-12 S Membrane
MCPNGMEK_01336 1.4e-287 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
MCPNGMEK_01337 0.0 tetP J Elongation factor G, domain IV
MCPNGMEK_01338 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
MCPNGMEK_01339 2.7e-304 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MCPNGMEK_01340 3.6e-82
MCPNGMEK_01341 1.7e-245 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
MCPNGMEK_01342 8e-182 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
MCPNGMEK_01343 2.2e-168 ybeM S Carbon-nitrogen hydrolase
MCPNGMEK_01344 3.3e-117 S Sel1-like repeats.
MCPNGMEK_01345 4.8e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MCPNGMEK_01346 6.1e-113 S Putative inner membrane protein (DUF1819)
MCPNGMEK_01347 9.2e-127 S Domain of unknown function (DUF1788)
MCPNGMEK_01348 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
MCPNGMEK_01349 0.0 LV DNA restriction-modification system
MCPNGMEK_01350 0.0 K SIR2-like domain
MCPNGMEK_01351 6e-264 lexA 3.6.4.12 K Putative DNA-binding domain
MCPNGMEK_01352 0.0 thiN 2.7.6.2 H PglZ domain
MCPNGMEK_01353 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
MCPNGMEK_01354 2.1e-144
MCPNGMEK_01356 9.7e-191 mcrB L Restriction endonuclease
MCPNGMEK_01357 8.6e-30
MCPNGMEK_01358 1.2e-103 rarD 3.4.17.13 E Rard protein
MCPNGMEK_01359 1.4e-23 rarD S Rard protein
MCPNGMEK_01360 3.6e-179 I alpha/beta hydrolase fold
MCPNGMEK_01361 3.3e-208 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MCPNGMEK_01362 1.2e-100 sixA T Phosphoglycerate mutase family
MCPNGMEK_01363 3.9e-242 int L Phage integrase, N-terminal SAM-like domain
MCPNGMEK_01364 2.3e-27 S Predicted membrane protein (DUF2335)
MCPNGMEK_01365 1.8e-35 S Predicted membrane protein (DUF2335)
MCPNGMEK_01366 2.1e-31 K Transcriptional regulator
MCPNGMEK_01367 5.7e-12
MCPNGMEK_01368 5.4e-11
MCPNGMEK_01369 7.7e-166
MCPNGMEK_01370 1.5e-76
MCPNGMEK_01371 9.5e-105
MCPNGMEK_01372 9.2e-135 rlfA S Protein of unknown function (DUF3800)
MCPNGMEK_01373 3.1e-27
MCPNGMEK_01374 2.5e-10
MCPNGMEK_01375 8.9e-147 K BRO family, N-terminal domain
MCPNGMEK_01378 2.2e-37
MCPNGMEK_01380 7.9e-38
MCPNGMEK_01382 3.5e-94 ssb1 L Single-strand binding protein family
MCPNGMEK_01383 3.6e-276 K ParB-like nuclease domain
MCPNGMEK_01384 8.8e-149 K Transcriptional regulator
MCPNGMEK_01385 1.5e-26
MCPNGMEK_01386 2.6e-81 V HNH endonuclease
MCPNGMEK_01387 8.4e-110 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MCPNGMEK_01389 3e-50
MCPNGMEK_01391 5.2e-144
MCPNGMEK_01392 1.5e-35 N HicA toxin of bacterial toxin-antitoxin,
MCPNGMEK_01393 1.4e-74 S HicB_like antitoxin of bacterial toxin-antitoxin system
MCPNGMEK_01395 3.2e-32 K Transcriptional regulator
MCPNGMEK_01398 8.1e-66
MCPNGMEK_01399 6.7e-115 S Bifunctional DNA primase/polymerase, N-terminal
MCPNGMEK_01400 4.8e-69
MCPNGMEK_01401 0.0 S Terminase
MCPNGMEK_01402 1.4e-280 S Phage portal protein, SPP1 Gp6-like
MCPNGMEK_01403 7.4e-241
MCPNGMEK_01404 1.1e-43
MCPNGMEK_01405 3.3e-95
MCPNGMEK_01406 3.8e-176 S Phage capsid family
MCPNGMEK_01407 8.1e-65
MCPNGMEK_01408 9.8e-91
MCPNGMEK_01409 1.3e-78
MCPNGMEK_01410 6.1e-73
MCPNGMEK_01411 4.9e-72
MCPNGMEK_01412 4.2e-95
MCPNGMEK_01413 6.9e-84
MCPNGMEK_01414 6.3e-53
MCPNGMEK_01415 0.0 S Phage-related minor tail protein
MCPNGMEK_01416 1.1e-149 S phage tail
MCPNGMEK_01417 0.0 S Prophage endopeptidase tail
MCPNGMEK_01418 4.7e-67
MCPNGMEK_01419 2.8e-220
MCPNGMEK_01420 4.6e-39 MU outer membrane autotransporter barrel domain protein
MCPNGMEK_01421 1.3e-69
MCPNGMEK_01422 6.5e-67 S SPP1 phage holin
MCPNGMEK_01423 2.2e-127 3.5.1.28 M NLP P60 protein
MCPNGMEK_01427 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MCPNGMEK_01428 9.6e-163 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
MCPNGMEK_01430 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MCPNGMEK_01431 1.3e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MCPNGMEK_01432 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MCPNGMEK_01433 7.7e-282 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MCPNGMEK_01434 6.8e-181 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
MCPNGMEK_01435 7.7e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MCPNGMEK_01436 7.4e-180 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MCPNGMEK_01437 6.5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MCPNGMEK_01438 1e-16 K MerR family regulatory protein
MCPNGMEK_01439 5.6e-197 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MCPNGMEK_01440 1.7e-143
MCPNGMEK_01442 1.9e-15 KLT Protein tyrosine kinase
MCPNGMEK_01443 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MCPNGMEK_01444 2.4e-240 vbsD V MatE
MCPNGMEK_01445 3.3e-132 S Enoyl-(Acyl carrier protein) reductase
MCPNGMEK_01446 2.3e-133 magIII L endonuclease III
MCPNGMEK_01447 3.4e-94 laaE K Transcriptional regulator PadR-like family
MCPNGMEK_01448 8e-177 S Membrane transport protein
MCPNGMEK_01449 2.7e-69 4.1.1.44 S Cupin domain
MCPNGMEK_01450 7e-225 hipA 2.7.11.1 S HipA N-terminal domain
MCPNGMEK_01451 3.7e-41 K Helix-turn-helix
MCPNGMEK_01452 4e-49 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
MCPNGMEK_01453 5.4e-19
MCPNGMEK_01454 1.4e-101 K Bacterial regulatory proteins, tetR family
MCPNGMEK_01455 1.8e-92 T Domain of unknown function (DUF4234)
MCPNGMEK_01456 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
MCPNGMEK_01457 1.5e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MCPNGMEK_01458 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MCPNGMEK_01459 4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
MCPNGMEK_01460 1.3e-90 dkgB S Oxidoreductase, aldo keto reductase family protein
MCPNGMEK_01462 5.1e-289 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
MCPNGMEK_01463 0.0 pafB K WYL domain
MCPNGMEK_01464 7e-53
MCPNGMEK_01465 0.0 helY L DEAD DEAH box helicase
MCPNGMEK_01466 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MCPNGMEK_01467 7.3e-143 pgp 3.1.3.18 S HAD-hyrolase-like
MCPNGMEK_01470 1.6e-90 K Putative zinc ribbon domain
MCPNGMEK_01471 4.2e-126 S GyrI-like small molecule binding domain
MCPNGMEK_01472 3.3e-24 L DNA integration
MCPNGMEK_01474 5e-63
MCPNGMEK_01475 5.2e-119 K helix_turn_helix, mercury resistance
MCPNGMEK_01476 9.6e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
MCPNGMEK_01477 1.2e-141 S Bacterial protein of unknown function (DUF881)
MCPNGMEK_01478 2.6e-31 sbp S Protein of unknown function (DUF1290)
MCPNGMEK_01479 1.4e-173 S Bacterial protein of unknown function (DUF881)
MCPNGMEK_01480 1e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MCPNGMEK_01481 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
MCPNGMEK_01482 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
MCPNGMEK_01483 6.3e-101 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
MCPNGMEK_01484 2.3e-192 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MCPNGMEK_01485 4.4e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MCPNGMEK_01486 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MCPNGMEK_01487 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
MCPNGMEK_01488 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MCPNGMEK_01489 1.8e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MCPNGMEK_01490 5.7e-30
MCPNGMEK_01491 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MCPNGMEK_01492 1.2e-247
MCPNGMEK_01493 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MCPNGMEK_01494 1.9e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MCPNGMEK_01495 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MCPNGMEK_01496 7.7e-44 yajC U Preprotein translocase subunit
MCPNGMEK_01497 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MCPNGMEK_01498 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MCPNGMEK_01499 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MCPNGMEK_01500 1e-131 yebC K transcriptional regulatory protein
MCPNGMEK_01501 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
MCPNGMEK_01502 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MCPNGMEK_01503 6.4e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCPNGMEK_01506 2.6e-262
MCPNGMEK_01510 2.8e-156 S PAC2 family
MCPNGMEK_01511 5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MCPNGMEK_01512 3.2e-160 G Fructosamine kinase
MCPNGMEK_01513 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MCPNGMEK_01514 5.9e-201 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MCPNGMEK_01515 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
MCPNGMEK_01516 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MCPNGMEK_01517 1.1e-142 yoaK S Protein of unknown function (DUF1275)
MCPNGMEK_01518 4.4e-253 brnQ U Component of the transport system for branched-chain amino acids
MCPNGMEK_01520 6.1e-244 mepA_6 V MatE
MCPNGMEK_01521 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
MCPNGMEK_01522 3.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MCPNGMEK_01523 8e-33 secG U Preprotein translocase SecG subunit
MCPNGMEK_01524 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MCPNGMEK_01525 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
MCPNGMEK_01526 3.1e-173 whiA K May be required for sporulation
MCPNGMEK_01527 1.5e-177 rapZ S Displays ATPase and GTPase activities
MCPNGMEK_01528 4.3e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
MCPNGMEK_01529 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MCPNGMEK_01530 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MCPNGMEK_01531 2.1e-77
MCPNGMEK_01532 7.1e-28 V MacB-like periplasmic core domain
MCPNGMEK_01533 3.3e-118 K Transcriptional regulatory protein, C terminal
MCPNGMEK_01534 3.9e-233 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MCPNGMEK_01535 4.5e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MCPNGMEK_01536 8.9e-303 ybiT S ABC transporter
MCPNGMEK_01537 1.4e-197 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MCPNGMEK_01538 3e-308 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MCPNGMEK_01539 2.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
MCPNGMEK_01540 2.3e-215 GK ROK family
MCPNGMEK_01541 1.5e-177 2.7.1.2 GK ROK family
MCPNGMEK_01542 3.3e-288 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
MCPNGMEK_01543 1e-168 G ABC transporter permease
MCPNGMEK_01544 8.1e-174 G Binding-protein-dependent transport system inner membrane component
MCPNGMEK_01545 1.1e-247 G Bacterial extracellular solute-binding protein
MCPNGMEK_01546 7.1e-308 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MCPNGMEK_01547 5.3e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MCPNGMEK_01548 1.4e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MCPNGMEK_01549 1.7e-229 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MCPNGMEK_01550 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
MCPNGMEK_01551 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MCPNGMEK_01552 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MCPNGMEK_01553 2.7e-128 3.2.1.8 S alpha beta
MCPNGMEK_01554 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MCPNGMEK_01555 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
MCPNGMEK_01556 5.8e-88 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MCPNGMEK_01557 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
MCPNGMEK_01558 3.4e-91
MCPNGMEK_01559 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
MCPNGMEK_01560 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
MCPNGMEK_01561 1.7e-277 G ABC transporter substrate-binding protein
MCPNGMEK_01562 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
MCPNGMEK_01563 1.8e-130 M Peptidase family M23
MCPNGMEK_01565 2.1e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MCPNGMEK_01566 3.1e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
MCPNGMEK_01567 2.7e-160 yeaZ 2.3.1.234 O Glycoprotease family
MCPNGMEK_01568 1.7e-119 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
MCPNGMEK_01569 4.8e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
MCPNGMEK_01570 0.0 comE S Competence protein
MCPNGMEK_01571 6.8e-84 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
MCPNGMEK_01572 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MCPNGMEK_01573 5.8e-169 ET Bacterial periplasmic substrate-binding proteins
MCPNGMEK_01574 3.7e-171 corA P CorA-like Mg2+ transporter protein
MCPNGMEK_01575 3.6e-162 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MCPNGMEK_01576 1.4e-300 E Serine carboxypeptidase
MCPNGMEK_01577 0.0 S Psort location Cytoplasmic, score 8.87
MCPNGMEK_01578 2.8e-116 S Domain of unknown function (DUF4194)
MCPNGMEK_01579 8.8e-284 S Psort location Cytoplasmic, score 8.87
MCPNGMEK_01580 9.6e-163 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MCPNGMEK_01581 7.6e-64 yeaO K Protein of unknown function, DUF488
MCPNGMEK_01582 6.6e-121 ydaF_1 J Acetyltransferase (GNAT) domain
MCPNGMEK_01583 2.6e-91 MA20_25245 K FR47-like protein
MCPNGMEK_01584 7e-56 K Transcriptional regulator
MCPNGMEK_01585 6.9e-37 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
MCPNGMEK_01586 1.4e-33 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MCPNGMEK_01588 1.2e-185 S Acetyltransferase (GNAT) domain
MCPNGMEK_01589 1.4e-132 S SOS response associated peptidase (SRAP)
MCPNGMEK_01590 2.5e-100
MCPNGMEK_01591 6.2e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCPNGMEK_01592 3.4e-164 rpoC M heme binding
MCPNGMEK_01593 5.3e-150 EGP Major facilitator Superfamily
MCPNGMEK_01595 8e-160
MCPNGMEK_01596 4.9e-116 ypjC S Putative ABC-transporter type IV
MCPNGMEK_01597 2.3e-110 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
MCPNGMEK_01598 4.8e-193 V VanZ like family
MCPNGMEK_01599 1.7e-148 KT RESPONSE REGULATOR receiver
MCPNGMEK_01600 2.7e-70 pdxH S Pfam:Pyridox_oxidase
MCPNGMEK_01601 5.7e-142 yijF S Domain of unknown function (DUF1287)
MCPNGMEK_01602 5e-133 C Putative TM nitroreductase
MCPNGMEK_01603 6.8e-117
MCPNGMEK_01605 8.4e-256 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
MCPNGMEK_01606 1.3e-78 S Bacterial PH domain
MCPNGMEK_01607 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MCPNGMEK_01608 2.4e-69 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MCPNGMEK_01609 3.2e-264 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MCPNGMEK_01611 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MCPNGMEK_01612 1.6e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MCPNGMEK_01613 4.3e-95
MCPNGMEK_01614 1.3e-240 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MCPNGMEK_01615 7.8e-285 thrC 4.2.3.1 E Threonine synthase N terminus
MCPNGMEK_01616 1.5e-121 S ABC-2 family transporter protein
MCPNGMEK_01617 2.8e-126 S ABC-2 family transporter protein
MCPNGMEK_01618 1.2e-177 V ATPases associated with a variety of cellular activities
MCPNGMEK_01619 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
MCPNGMEK_01620 8.9e-124 S Haloacid dehalogenase-like hydrolase
MCPNGMEK_01621 2.9e-294 recN L May be involved in recombinational repair of damaged DNA
MCPNGMEK_01622 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MCPNGMEK_01623 9.2e-238 trkB P Cation transport protein
MCPNGMEK_01624 5.2e-116 trkA P TrkA-N domain
MCPNGMEK_01625 3.6e-104
MCPNGMEK_01626 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MCPNGMEK_01628 1.3e-190 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MCPNGMEK_01629 3.6e-159 L Tetratricopeptide repeat
MCPNGMEK_01630 1.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MCPNGMEK_01631 1.6e-143 S Putative ABC-transporter type IV
MCPNGMEK_01632 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MCPNGMEK_01633 1.2e-280 argH 4.3.2.1 E argininosuccinate lyase
MCPNGMEK_01634 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MCPNGMEK_01635 1.3e-285 K Putative DNA-binding domain
MCPNGMEK_01636 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
MCPNGMEK_01637 1.9e-155 S Domain of unknown function (DUF4357)
MCPNGMEK_01638 2.4e-30
MCPNGMEK_01639 4.7e-179 L Phage integrase family
MCPNGMEK_01640 9.5e-67 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
MCPNGMEK_01641 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MCPNGMEK_01642 1.1e-84 argR K Regulates arginine biosynthesis genes
MCPNGMEK_01643 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MCPNGMEK_01644 2.5e-247 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
MCPNGMEK_01645 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MCPNGMEK_01646 7.9e-216 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MCPNGMEK_01647 2.4e-206 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MCPNGMEK_01648 3.6e-90
MCPNGMEK_01649 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
MCPNGMEK_01650 3.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MCPNGMEK_01651 8.3e-162 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCPNGMEK_01652 5.8e-135 ybbL V ATPases associated with a variety of cellular activities
MCPNGMEK_01653 2.5e-136 ybbM V Uncharacterised protein family (UPF0014)
MCPNGMEK_01654 3.6e-54 IQ oxidoreductase activity
MCPNGMEK_01656 9.2e-106 K AraC-like ligand binding domain
MCPNGMEK_01657 4.3e-239 rutG F Permease family
MCPNGMEK_01658 1.1e-158 3.1.3.73 G Phosphoglycerate mutase family
MCPNGMEK_01659 6.5e-188 MA20_14895 S Conserved hypothetical protein 698
MCPNGMEK_01660 7.8e-146 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
MCPNGMEK_01661 1.3e-119 3.1.3.27 E haloacid dehalogenase-like hydrolase
MCPNGMEK_01662 1.7e-290 2.4.1.166 GT2 M Glycosyltransferase like family 2
MCPNGMEK_01664 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
MCPNGMEK_01665 2.5e-126 ypfH S Phospholipase/Carboxylesterase
MCPNGMEK_01666 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MCPNGMEK_01667 2.5e-24
MCPNGMEK_01668 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MCPNGMEK_01669 2.8e-66 S Zincin-like metallopeptidase
MCPNGMEK_01670 8.2e-91 S Helix-turn-helix
MCPNGMEK_01671 9.3e-199 S Short C-terminal domain
MCPNGMEK_01672 2.7e-22
MCPNGMEK_01673 1.1e-149
MCPNGMEK_01674 2.6e-79 K Psort location Cytoplasmic, score
MCPNGMEK_01675 1.2e-257 KLT Protein tyrosine kinase
MCPNGMEK_01676 7.9e-66 S Cupin 2, conserved barrel domain protein
MCPNGMEK_01677 1.2e-157 ksgA 2.1.1.182 J Methyltransferase domain
MCPNGMEK_01678 5.6e-59 yccF S Inner membrane component domain
MCPNGMEK_01679 6e-121 E Psort location Cytoplasmic, score 8.87
MCPNGMEK_01680 5.2e-248 XK27_00240 K Fic/DOC family
MCPNGMEK_01681 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MCPNGMEK_01682 5.9e-28 mtnE 2.6.1.83 E Aminotransferase class I and II
MCPNGMEK_01683 5.5e-183 mtnE 2.6.1.83 E Aminotransferase class I and II
MCPNGMEK_01684 2.2e-93 metI P Binding-protein-dependent transport system inner membrane component
MCPNGMEK_01685 4.4e-203 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MCPNGMEK_01686 1.8e-73 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
MCPNGMEK_01687 3.1e-80 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
MCPNGMEK_01688 7.7e-188 acoA 1.2.4.1 C Dehydrogenase E1 component
MCPNGMEK_01689 1.4e-147 P NLPA lipoprotein
MCPNGMEK_01690 3.4e-169 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
MCPNGMEK_01691 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MCPNGMEK_01692 1e-265 pip 3.4.11.5 S alpha/beta hydrolase fold
MCPNGMEK_01693 0.0 tcsS2 T Histidine kinase
MCPNGMEK_01694 6.1e-132 K helix_turn_helix, Lux Regulon
MCPNGMEK_01695 0.0 phoN I PAP2 superfamily
MCPNGMEK_01696 0.0 MV MacB-like periplasmic core domain
MCPNGMEK_01697 3.4e-162 V ABC transporter, ATP-binding protein
MCPNGMEK_01698 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
MCPNGMEK_01699 1.6e-157 S Putative ABC-transporter type IV
MCPNGMEK_01700 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MCPNGMEK_01701 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
MCPNGMEK_01702 6.1e-285 dprA 5.99.1.2 LU DNA recombination-mediator protein A
MCPNGMEK_01703 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
MCPNGMEK_01704 3e-71 yraN L Belongs to the UPF0102 family
MCPNGMEK_01705 4.6e-185 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
MCPNGMEK_01706 1.1e-118 safC S O-methyltransferase
MCPNGMEK_01707 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
MCPNGMEK_01708 1.2e-225 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MCPNGMEK_01709 1e-234 patB 4.4.1.8 E Aminotransferase, class I II
MCPNGMEK_01712 2e-244 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MCPNGMEK_01713 1.5e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MCPNGMEK_01714 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MCPNGMEK_01715 3.6e-255 clcA_2 P Voltage gated chloride channel
MCPNGMEK_01716 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MCPNGMEK_01717 2.4e-250 rnd 3.1.13.5 J 3'-5' exonuclease
MCPNGMEK_01718 1.3e-113 S Protein of unknown function (DUF3000)
MCPNGMEK_01719 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MCPNGMEK_01720 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MCPNGMEK_01721 4.9e-40
MCPNGMEK_01722 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MCPNGMEK_01723 1.6e-224 S Peptidase dimerisation domain
MCPNGMEK_01724 2.1e-94 P ABC-type metal ion transport system permease component
MCPNGMEK_01725 5.5e-166 S Sucrose-6F-phosphate phosphohydrolase
MCPNGMEK_01726 1.5e-128 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MCPNGMEK_01727 8.4e-71
MCPNGMEK_01728 4.3e-132
MCPNGMEK_01729 4.1e-121
MCPNGMEK_01730 1.1e-29
MCPNGMEK_01731 3.9e-188 S Helix-turn-helix domain
MCPNGMEK_01732 3e-43
MCPNGMEK_01733 2.6e-91 S Transcription factor WhiB
MCPNGMEK_01734 2.2e-117 parA D AAA domain
MCPNGMEK_01735 3.7e-238 S HipA-like C-terminal domain
MCPNGMEK_01736 5.8e-48
MCPNGMEK_01737 9.4e-60
MCPNGMEK_01738 1.3e-82
MCPNGMEK_01739 0.0 topB 5.99.1.2 L DNA topoisomerase
MCPNGMEK_01740 1.3e-87
MCPNGMEK_01741 3e-55
MCPNGMEK_01742 5.5e-42 S Protein of unknown function (DUF2442)
MCPNGMEK_01743 4.9e-66 S Bacterial mobilisation protein (MobC)
MCPNGMEK_01744 4.4e-305 ltrBE1 U Relaxase/Mobilisation nuclease domain
MCPNGMEK_01745 2.5e-168 S Protein of unknown function (DUF3801)
MCPNGMEK_01746 2.7e-29 L DNA integration
MCPNGMEK_01747 1.1e-26
MCPNGMEK_01748 1.5e-146 fic D Fic/DOC family
MCPNGMEK_01749 1.6e-249 L Phage integrase family
MCPNGMEK_01750 2.4e-206 L Transposase and inactivated derivatives IS30 family
MCPNGMEK_01751 2.3e-07
MCPNGMEK_01752 5e-50 relB L RelB antitoxin
MCPNGMEK_01753 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
MCPNGMEK_01754 1.9e-208 E Belongs to the peptidase S1B family
MCPNGMEK_01755 1.7e-13
MCPNGMEK_01756 2.7e-28
MCPNGMEK_01757 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MCPNGMEK_01758 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MCPNGMEK_01759 1.4e-47 S Domain of unknown function (DUF4193)
MCPNGMEK_01760 1.4e-187 S Protein of unknown function (DUF3071)
MCPNGMEK_01761 1.3e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
MCPNGMEK_01762 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MCPNGMEK_01763 0.0 lhr L DEAD DEAH box helicase
MCPNGMEK_01764 5.7e-36 K Transcriptional regulator
MCPNGMEK_01765 2.3e-278 aspA 4.3.1.1 E Fumarase C C-terminus
MCPNGMEK_01766 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MCPNGMEK_01767 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MCPNGMEK_01768 3.5e-123
MCPNGMEK_01769 1.4e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
MCPNGMEK_01770 0.0 pknL 2.7.11.1 KLT PASTA
MCPNGMEK_01771 4.6e-134 plsC2 2.3.1.51 I Phosphate acyltransferases
MCPNGMEK_01772 1.5e-109
MCPNGMEK_01773 6.4e-193 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MCPNGMEK_01774 3.6e-25 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MCPNGMEK_01775 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MCPNGMEK_01776 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MCPNGMEK_01777 1e-07
MCPNGMEK_01778 7.1e-74 recX S Modulates RecA activity
MCPNGMEK_01779 4.7e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MCPNGMEK_01780 3.7e-40 S Protein of unknown function (DUF3046)
MCPNGMEK_01781 7.3e-81 K Helix-turn-helix XRE-family like proteins
MCPNGMEK_01782 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
MCPNGMEK_01783 3.2e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MCPNGMEK_01784 0.0 ftsK D FtsK SpoIIIE family protein
MCPNGMEK_01785 1.2e-137 fic D Fic/DOC family
MCPNGMEK_01786 3.1e-185 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MCPNGMEK_01787 5.7e-280 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MCPNGMEK_01788 4.2e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
MCPNGMEK_01789 7.5e-172 ydeD EG EamA-like transporter family
MCPNGMEK_01790 6.6e-132 ybhL S Belongs to the BI1 family
MCPNGMEK_01791 1e-92 S Domain of unknown function (DUF5067)
MCPNGMEK_01792 3.9e-265 T Histidine kinase
MCPNGMEK_01793 1.1e-116 K helix_turn_helix, Lux Regulon
MCPNGMEK_01794 0.0 S Protein of unknown function DUF262
MCPNGMEK_01795 3.4e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MCPNGMEK_01796 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MCPNGMEK_01797 4.1e-239 carA 6.3.5.5 F Belongs to the CarA family
MCPNGMEK_01798 1.3e-93 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MCPNGMEK_01799 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MCPNGMEK_01801 1e-191 EGP Transmembrane secretion effector
MCPNGMEK_01802 3.6e-210 S Esterase-like activity of phytase
MCPNGMEK_01803 3.3e-87 xynX5 3.1.4.46, 3.2.1.8 I PAP2 superfamily
MCPNGMEK_01804 2.3e-231 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MCPNGMEK_01805 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MCPNGMEK_01806 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MCPNGMEK_01807 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MCPNGMEK_01809 3.1e-200 ltaE 4.1.2.48 E Beta-eliminating lyase
MCPNGMEK_01810 6.3e-229 M Glycosyl transferase 4-like domain
MCPNGMEK_01811 0.0 M Parallel beta-helix repeats
MCPNGMEK_01812 1.3e-235 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MCPNGMEK_01813 3.8e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MCPNGMEK_01814 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
MCPNGMEK_01815 1.3e-114
MCPNGMEK_01816 2.1e-93 S Protein of unknown function (DUF4230)
MCPNGMEK_01817 4.3e-152 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
MCPNGMEK_01818 8.9e-33 K DNA-binding transcription factor activity
MCPNGMEK_01819 4.7e-69 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCPNGMEK_01820 2e-32
MCPNGMEK_01821 5.5e-305 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
MCPNGMEK_01822 1.3e-292 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MCPNGMEK_01823 6.8e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MCPNGMEK_01824 5e-240 purD 6.3.4.13 F Belongs to the GARS family
MCPNGMEK_01825 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MCPNGMEK_01826 2.6e-200 S Putative esterase
MCPNGMEK_01827 0.0 lysX S Uncharacterised conserved protein (DUF2156)
MCPNGMEK_01829 2.7e-163 P Zinc-uptake complex component A periplasmic
MCPNGMEK_01830 1.9e-141 S cobalamin synthesis protein
MCPNGMEK_01831 6.1e-48 rpmB J Ribosomal L28 family
MCPNGMEK_01832 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCPNGMEK_01833 2e-42 rpmE2 J Ribosomal protein L31
MCPNGMEK_01834 8.2e-15 rpmJ J Ribosomal protein L36
MCPNGMEK_01835 7.9e-24 J Ribosomal L32p protein family
MCPNGMEK_01836 1.6e-202 ycgR S Predicted permease
MCPNGMEK_01837 2.6e-154 S TIGRFAM TIGR03943 family protein
MCPNGMEK_01838 1.5e-45
MCPNGMEK_01839 5.1e-74 zur P Belongs to the Fur family
MCPNGMEK_01840 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MCPNGMEK_01841 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MCPNGMEK_01842 2e-180 adh3 C Zinc-binding dehydrogenase
MCPNGMEK_01843 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MCPNGMEK_01845 1.4e-44 S Memo-like protein
MCPNGMEK_01846 2e-230 K Putative ATP-dependent DNA helicase recG C-terminal
MCPNGMEK_01847 2.7e-160 K Helix-turn-helix domain, rpiR family
MCPNGMEK_01848 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MCPNGMEK_01849 2.3e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
MCPNGMEK_01850 9e-264 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MCPNGMEK_01851 1.2e-269 yhdG E aromatic amino acid transport protein AroP K03293
MCPNGMEK_01852 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MCPNGMEK_01853 1.4e-10 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MCPNGMEK_01854 2.3e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MCPNGMEK_01855 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MCPNGMEK_01856 2.2e-221 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MCPNGMEK_01857 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
MCPNGMEK_01858 4.4e-109

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)