ORF_ID e_value Gene_name EC_number CAZy COGs Description
EAFBLIHF_00002 7.8e-157
EAFBLIHF_00003 8.9e-77
EAFBLIHF_00006 1.3e-07
EAFBLIHF_00015 3.8e-59
EAFBLIHF_00016 7e-153 L Psort location Cytoplasmic, score
EAFBLIHF_00017 4.8e-153 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
EAFBLIHF_00018 4.2e-178 recT L RecT family
EAFBLIHF_00022 1.8e-17
EAFBLIHF_00023 5e-142 K BRO family, N-terminal domain
EAFBLIHF_00024 8e-31 K Helix-turn-helix XRE-family like proteins
EAFBLIHF_00025 5.3e-72 K Cro/C1-type HTH DNA-binding domain
EAFBLIHF_00026 1e-83 E IrrE N-terminal-like domain
EAFBLIHF_00027 7.6e-30 M Host cell surface-exposed lipoprotein
EAFBLIHF_00028 1.3e-51
EAFBLIHF_00029 2.5e-211 L Belongs to the 'phage' integrase family
EAFBLIHF_00030 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EAFBLIHF_00031 6.8e-262 yfnA E amino acid
EAFBLIHF_00032 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EAFBLIHF_00033 3.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EAFBLIHF_00034 4.1e-40 ylqC S Belongs to the UPF0109 family
EAFBLIHF_00035 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EAFBLIHF_00036 2.7e-250 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EAFBLIHF_00037 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EAFBLIHF_00038 2.2e-181 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EAFBLIHF_00039 0.0 smc D Required for chromosome condensation and partitioning
EAFBLIHF_00040 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EAFBLIHF_00041 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAFBLIHF_00042 7.3e-189 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EAFBLIHF_00043 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EAFBLIHF_00044 0.0 yloV S DAK2 domain fusion protein YloV
EAFBLIHF_00045 4.7e-58 asp S Asp23 family, cell envelope-related function
EAFBLIHF_00046 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EAFBLIHF_00047 7.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
EAFBLIHF_00048 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EAFBLIHF_00049 2.6e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EAFBLIHF_00050 0.0 KLT serine threonine protein kinase
EAFBLIHF_00051 6.9e-133 stp 3.1.3.16 T phosphatase
EAFBLIHF_00052 2e-255 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EAFBLIHF_00053 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EAFBLIHF_00054 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EAFBLIHF_00055 5.1e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EAFBLIHF_00056 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EAFBLIHF_00057 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EAFBLIHF_00058 1.7e-54
EAFBLIHF_00059 2.3e-264 recN L May be involved in recombinational repair of damaged DNA
EAFBLIHF_00060 1e-78 argR K Regulates arginine biosynthesis genes
EAFBLIHF_00061 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EAFBLIHF_00062 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EAFBLIHF_00063 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EAFBLIHF_00064 6.7e-203 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EAFBLIHF_00065 3.4e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EAFBLIHF_00066 3.6e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EAFBLIHF_00067 2.2e-70 yqhY S Asp23 family, cell envelope-related function
EAFBLIHF_00068 4.5e-123 J 2'-5' RNA ligase superfamily
EAFBLIHF_00069 1.7e-204 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EAFBLIHF_00070 8.6e-133 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EAFBLIHF_00071 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EAFBLIHF_00072 7.4e-55 ysxB J Cysteine protease Prp
EAFBLIHF_00073 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
EAFBLIHF_00074 2.6e-112 K Transcriptional regulator
EAFBLIHF_00077 6.5e-90 dut S Protein conserved in bacteria
EAFBLIHF_00078 1.8e-187
EAFBLIHF_00079 2.7e-152
EAFBLIHF_00080 1.3e-51 S Iron-sulfur cluster assembly protein
EAFBLIHF_00081 5e-101 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EAFBLIHF_00082 1.3e-156 P Belongs to the nlpA lipoprotein family
EAFBLIHF_00083 3.9e-12
EAFBLIHF_00084 1.1e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
EAFBLIHF_00085 4e-297 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAFBLIHF_00086 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
EAFBLIHF_00087 1e-178 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EAFBLIHF_00088 5.9e-22 S Protein of unknown function (DUF3042)
EAFBLIHF_00089 9.1e-68 yqhL P Rhodanese-like protein
EAFBLIHF_00090 1.5e-183 glk 2.7.1.2 G Glucokinase
EAFBLIHF_00091 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
EAFBLIHF_00092 2.2e-114 gluP 3.4.21.105 S Peptidase, S54 family
EAFBLIHF_00093 1.4e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EAFBLIHF_00094 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EAFBLIHF_00095 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
EAFBLIHF_00096 0.0 S membrane
EAFBLIHF_00097 4e-71 yneR S Belongs to the HesB IscA family
EAFBLIHF_00098 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EAFBLIHF_00099 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
EAFBLIHF_00100 6.9e-113 rlpA M PFAM NLP P60 protein
EAFBLIHF_00101 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EAFBLIHF_00102 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EAFBLIHF_00103 2.6e-58 yodB K Transcriptional regulator, HxlR family
EAFBLIHF_00104 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
EAFBLIHF_00105 2.2e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAFBLIHF_00106 8.2e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EAFBLIHF_00107 1.5e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EAFBLIHF_00108 9.3e-71 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EAFBLIHF_00109 7.8e-236 V MatE
EAFBLIHF_00110 1.8e-268 yjeM E Amino Acid
EAFBLIHF_00111 9.8e-280 arlS 2.7.13.3 T Histidine kinase
EAFBLIHF_00112 1.5e-121 K response regulator
EAFBLIHF_00113 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EAFBLIHF_00114 2.9e-99 yceD S Uncharacterized ACR, COG1399
EAFBLIHF_00115 2.9e-215 ylbM S Belongs to the UPF0348 family
EAFBLIHF_00116 1.4e-141 yqeM Q Methyltransferase
EAFBLIHF_00117 1.3e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EAFBLIHF_00118 9.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
EAFBLIHF_00119 7.9e-125 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EAFBLIHF_00120 1.9e-47 yhbY J RNA-binding protein
EAFBLIHF_00121 5.6e-219 yqeH S Ribosome biogenesis GTPase YqeH
EAFBLIHF_00122 2.8e-96 yqeG S HAD phosphatase, family IIIA
EAFBLIHF_00123 4.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EAFBLIHF_00124 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EAFBLIHF_00125 6.3e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EAFBLIHF_00126 1e-173 dnaI L Primosomal protein DnaI
EAFBLIHF_00127 3.2e-208 dnaB L replication initiation and membrane attachment
EAFBLIHF_00128 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EAFBLIHF_00129 9.3e-104 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EAFBLIHF_00130 8.8e-161 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EAFBLIHF_00131 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EAFBLIHF_00132 1.8e-119 yoaK S Protein of unknown function (DUF1275)
EAFBLIHF_00133 1.4e-119 ybhL S Belongs to the BI1 family
EAFBLIHF_00134 1.2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EAFBLIHF_00135 2.9e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EAFBLIHF_00136 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EAFBLIHF_00137 7.5e-58 ytzB S Small secreted protein
EAFBLIHF_00138 2.6e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
EAFBLIHF_00139 1.1e-186 iolS C Aldo keto reductase
EAFBLIHF_00140 3.5e-293 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
EAFBLIHF_00141 6e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_00142 1.5e-284 A chlorophyll binding
EAFBLIHF_00143 2.2e-182 S YSIRK type signal peptide
EAFBLIHF_00144 2.8e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EAFBLIHF_00145 1.7e-221 ecsB U ABC transporter
EAFBLIHF_00146 1.2e-137 ecsA V ABC transporter, ATP-binding protein
EAFBLIHF_00147 8.3e-78 hit FG histidine triad
EAFBLIHF_00149 1.2e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EAFBLIHF_00150 0.0 L AAA domain
EAFBLIHF_00151 1.3e-229 yhaO L Ser Thr phosphatase family protein
EAFBLIHF_00152 2.6e-40 yheA S Belongs to the UPF0342 family
EAFBLIHF_00153 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EAFBLIHF_00154 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EAFBLIHF_00155 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EAFBLIHF_00156 8.4e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EAFBLIHF_00158 3.3e-40
EAFBLIHF_00159 1e-43
EAFBLIHF_00160 4.2e-217 folP 2.5.1.15 H dihydropteroate synthase
EAFBLIHF_00161 2.6e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
EAFBLIHF_00162 6.7e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EAFBLIHF_00163 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
EAFBLIHF_00164 1.2e-94 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
EAFBLIHF_00165 1.1e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EAFBLIHF_00166 8.7e-74
EAFBLIHF_00168 1.9e-43
EAFBLIHF_00169 2.8e-120 S CAAX protease self-immunity
EAFBLIHF_00170 2.1e-32
EAFBLIHF_00171 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAFBLIHF_00172 4.6e-188 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
EAFBLIHF_00173 5.9e-114
EAFBLIHF_00174 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
EAFBLIHF_00175 3.2e-189 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EAFBLIHF_00176 1.9e-86 uspA T Belongs to the universal stress protein A family
EAFBLIHF_00177 8.7e-278 pepV 3.5.1.18 E dipeptidase PepV
EAFBLIHF_00178 1.2e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EAFBLIHF_00179 6.4e-304 ytgP S Polysaccharide biosynthesis protein
EAFBLIHF_00180 4.5e-42
EAFBLIHF_00181 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EAFBLIHF_00182 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EAFBLIHF_00183 2.5e-100 tag 3.2.2.20 L glycosylase
EAFBLIHF_00184 1.5e-29
EAFBLIHF_00185 4.2e-259 EGP Major facilitator Superfamily
EAFBLIHF_00186 4.3e-85 perR P Belongs to the Fur family
EAFBLIHF_00187 2.2e-233 cycA E Amino acid permease
EAFBLIHF_00188 2.6e-103 V VanZ like family
EAFBLIHF_00189 1e-23
EAFBLIHF_00190 2.2e-85 S Short repeat of unknown function (DUF308)
EAFBLIHF_00191 1.5e-79 S Psort location Cytoplasmic, score
EAFBLIHF_00192 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
EAFBLIHF_00193 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
EAFBLIHF_00194 1e-156 yeaE S Aldo keto
EAFBLIHF_00195 4e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
EAFBLIHF_00196 7.3e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
EAFBLIHF_00197 5.8e-151 xth 3.1.11.2 L exodeoxyribonuclease III
EAFBLIHF_00198 1.9e-95 lytE M LysM domain protein
EAFBLIHF_00199 0.0 oppD EP Psort location Cytoplasmic, score
EAFBLIHF_00200 6.8e-43 lytE M LysM domain protein
EAFBLIHF_00201 1.1e-166 sufD O Uncharacterized protein family (UPF0051)
EAFBLIHF_00202 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EAFBLIHF_00203 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EAFBLIHF_00204 4.2e-240 lmrB EGP Major facilitator Superfamily
EAFBLIHF_00205 1.1e-101 2.3.1.128 K Acetyltransferase (GNAT) domain
EAFBLIHF_00217 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
EAFBLIHF_00218 1.3e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EAFBLIHF_00219 1.6e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
EAFBLIHF_00220 1.2e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EAFBLIHF_00221 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAFBLIHF_00222 2.7e-39 ptsH G phosphocarrier protein HPR
EAFBLIHF_00223 2.2e-27
EAFBLIHF_00224 0.0 clpE O Belongs to the ClpA ClpB family
EAFBLIHF_00225 1.7e-100 S Pfam:DUF3816
EAFBLIHF_00226 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
EAFBLIHF_00227 2.6e-118
EAFBLIHF_00228 1e-159 V ABC transporter, ATP-binding protein
EAFBLIHF_00229 1.2e-64 gntR1 K Transcriptional regulator, GntR family
EAFBLIHF_00230 2.1e-171 3.2.1.23, 3.2.1.89 G arabinogalactan endo-1,4-beta-galactosidase activity
EAFBLIHF_00231 3.5e-282 ganB 3.2.1.89 G arabinogalactan
EAFBLIHF_00232 6.7e-40 S dextransucrase activity
EAFBLIHF_00233 3.6e-45 L PFAM Integrase catalytic region
EAFBLIHF_00234 2.5e-163 L hmm pf00665
EAFBLIHF_00235 5.1e-57 L Helix-turn-helix domain
EAFBLIHF_00236 2e-32 L Helix-turn-helix domain
EAFBLIHF_00237 4.6e-247 L Transposase
EAFBLIHF_00238 2.1e-29 L Transposase
EAFBLIHF_00239 1.7e-57 L PFAM Integrase catalytic region
EAFBLIHF_00240 1.1e-96 L Helix-turn-helix domain
EAFBLIHF_00241 1.1e-115 L PFAM Integrase, catalytic core
EAFBLIHF_00242 7.8e-38 L Helix-turn-helix domain
EAFBLIHF_00243 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
EAFBLIHF_00244 3.1e-103 M NlpC P60 family protein
EAFBLIHF_00245 1.7e-262 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_00246 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_00247 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EAFBLIHF_00248 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EAFBLIHF_00249 2.1e-288 S Psort location CytoplasmicMembrane, score
EAFBLIHF_00250 1.4e-164 yueF S AI-2E family transporter
EAFBLIHF_00251 3.2e-119 S dextransucrase activity
EAFBLIHF_00252 1.1e-225 S Uncharacterised protein family (UPF0236)
EAFBLIHF_00253 2e-120 L PFAM Integrase catalytic region
EAFBLIHF_00254 5.8e-106 L Helix-turn-helix domain
EAFBLIHF_00255 2.1e-79 L hmm pf00665
EAFBLIHF_00256 1.2e-132 O Bacterial dnaA protein
EAFBLIHF_00257 1.6e-238 L Integrase core domain
EAFBLIHF_00258 5.4e-178 M Glycosyltransferase like family 2
EAFBLIHF_00259 3e-27
EAFBLIHF_00260 5.9e-135 M repeat protein
EAFBLIHF_00261 1e-157 3.2.1.96, 3.5.1.28 GH73 M repeat protein
EAFBLIHF_00262 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_00263 1.6e-141 acmD M repeat protein
EAFBLIHF_00264 1.7e-196 S enterobacterial common antigen metabolic process
EAFBLIHF_00265 9.6e-194 M transferase activity, transferring glycosyl groups
EAFBLIHF_00266 9.3e-200 waaB GT4 M Glycosyl transferases group 1
EAFBLIHF_00267 4.9e-260 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
EAFBLIHF_00268 1.4e-105 M biosynthesis protein
EAFBLIHF_00269 4.3e-217 cps3F
EAFBLIHF_00270 6e-221 glf 5.4.99.9 M UDP-galactopyranose mutase
EAFBLIHF_00271 1.7e-122 rfbP 2.7.8.6 M Bacterial sugar transferase
EAFBLIHF_00272 9.8e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
EAFBLIHF_00273 1.1e-149 cps1D M Domain of unknown function (DUF4422)
EAFBLIHF_00274 9.3e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
EAFBLIHF_00275 2.2e-31
EAFBLIHF_00276 5e-34 S Protein of unknown function (DUF2922)
EAFBLIHF_00277 8.5e-154 yihY S Belongs to the UPF0761 family
EAFBLIHF_00278 1.1e-281 yjeM E Amino Acid
EAFBLIHF_00279 1.7e-257 E Arginine ornithine antiporter
EAFBLIHF_00280 8.4e-223 arcT 2.6.1.1 E Aminotransferase
EAFBLIHF_00281 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
EAFBLIHF_00282 2.1e-79 fld C Flavodoxin
EAFBLIHF_00283 1.5e-74 gtcA S Teichoic acid glycosylation protein
EAFBLIHF_00284 3.6e-54
EAFBLIHF_00285 3.3e-211 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EAFBLIHF_00287 3.6e-233 yfmL 3.6.4.13 L DEAD DEAH box helicase
EAFBLIHF_00288 1.2e-191 mocA S Oxidoreductase
EAFBLIHF_00289 7e-62 S Domain of unknown function (DUF4828)
EAFBLIHF_00290 1.3e-110 yvdD 3.2.2.10 S Belongs to the LOG family
EAFBLIHF_00291 2.7e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EAFBLIHF_00292 1.3e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EAFBLIHF_00293 6.3e-201 S Protein of unknown function (DUF3114)
EAFBLIHF_00294 5.8e-82 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
EAFBLIHF_00295 7.6e-121 ybhL S Belongs to the BI1 family
EAFBLIHF_00296 3.7e-22
EAFBLIHF_00297 2.5e-97 K Acetyltransferase (GNAT) family
EAFBLIHF_00298 2.9e-78 K LytTr DNA-binding domain
EAFBLIHF_00299 5.6e-69 S Protein of unknown function (DUF3021)
EAFBLIHF_00300 1.1e-156 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
EAFBLIHF_00301 4.2e-77 XK27_00915 C Luciferase-like monooxygenase
EAFBLIHF_00302 9.5e-132 L transposase, IS605 OrfB family
EAFBLIHF_00303 2.2e-84 ogt 2.1.1.63 L Methyltransferase
EAFBLIHF_00304 1.4e-124 pnb C nitroreductase
EAFBLIHF_00305 2.5e-92
EAFBLIHF_00306 1e-84 yvbK 3.1.3.25 K GNAT family
EAFBLIHF_00307 3e-256 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
EAFBLIHF_00308 2.3e-207 amtB P ammonium transporter
EAFBLIHF_00309 4.4e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
EAFBLIHF_00310 7.9e-70 S PFAM Archaeal ATPase
EAFBLIHF_00311 3.1e-104 S PFAM Archaeal ATPase
EAFBLIHF_00312 0.0 XK27_08510 L Type III restriction protein res subunit
EAFBLIHF_00313 5.7e-52
EAFBLIHF_00314 1.1e-158 cylA V ABC transporter
EAFBLIHF_00315 1.7e-146 cylB V ABC-2 type transporter
EAFBLIHF_00316 1.4e-75 K LytTr DNA-binding domain
EAFBLIHF_00317 6.3e-61 S Protein of unknown function (DUF3021)
EAFBLIHF_00319 8.6e-184 L Plasmid pRiA4b ORF-3-like protein
EAFBLIHF_00321 7.6e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
EAFBLIHF_00322 4.8e-99 dps P Belongs to the Dps family
EAFBLIHF_00323 2.5e-36 copZ P PFAM Heavy metal transport detoxification protein
EAFBLIHF_00324 1.5e-90 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
EAFBLIHF_00325 7.2e-183 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
EAFBLIHF_00326 1.9e-38 3.6.1.13, 3.6.1.55 F NUDIX domain
EAFBLIHF_00327 1.3e-262 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_00328 6.3e-90 entB 3.5.1.19 Q Isochorismatase family
EAFBLIHF_00329 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
EAFBLIHF_00330 1.7e-113 3.1.21.3 V Type I restriction modification DNA specificity domain
EAFBLIHF_00331 2.4e-178 L Belongs to the 'phage' integrase family
EAFBLIHF_00332 1.1e-107 3.1.21.3 V Type I restriction modification DNA specificity domain
EAFBLIHF_00333 3.1e-300 hsdM 2.1.1.72 V type I restriction-modification system
EAFBLIHF_00334 5.4e-236
EAFBLIHF_00335 6.1e-268 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAFBLIHF_00337 3.5e-188 yegS 2.7.1.107 G Lipid kinase
EAFBLIHF_00338 2.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAFBLIHF_00339 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EAFBLIHF_00340 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAFBLIHF_00341 3.3e-203 camS S sex pheromone
EAFBLIHF_00342 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EAFBLIHF_00343 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EAFBLIHF_00344 9.4e-214 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EAFBLIHF_00345 3.5e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EAFBLIHF_00346 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
EAFBLIHF_00347 5.5e-141 IQ reductase
EAFBLIHF_00348 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
EAFBLIHF_00349 9.1e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EAFBLIHF_00350 1.2e-143 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EAFBLIHF_00351 1.2e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EAFBLIHF_00352 1.5e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EAFBLIHF_00353 1.9e-147 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EAFBLIHF_00354 1.1e-62 rplQ J Ribosomal protein L17
EAFBLIHF_00355 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EAFBLIHF_00356 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EAFBLIHF_00357 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EAFBLIHF_00358 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EAFBLIHF_00359 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EAFBLIHF_00360 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EAFBLIHF_00361 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EAFBLIHF_00362 6.8e-64 rplO J Binds to the 23S rRNA
EAFBLIHF_00363 2.9e-24 rpmD J Ribosomal protein L30
EAFBLIHF_00364 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EAFBLIHF_00365 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EAFBLIHF_00366 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EAFBLIHF_00367 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EAFBLIHF_00368 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EAFBLIHF_00369 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EAFBLIHF_00370 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EAFBLIHF_00371 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EAFBLIHF_00372 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EAFBLIHF_00373 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
EAFBLIHF_00374 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EAFBLIHF_00375 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EAFBLIHF_00376 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EAFBLIHF_00377 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EAFBLIHF_00378 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EAFBLIHF_00379 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EAFBLIHF_00380 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
EAFBLIHF_00381 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EAFBLIHF_00382 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EAFBLIHF_00383 5.4e-200 L Transposase
EAFBLIHF_00384 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EAFBLIHF_00385 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EAFBLIHF_00386 5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EAFBLIHF_00387 2.7e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
EAFBLIHF_00388 1.5e-201 ykiI
EAFBLIHF_00389 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EAFBLIHF_00390 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EAFBLIHF_00391 1e-110 K Bacterial regulatory proteins, tetR family
EAFBLIHF_00392 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EAFBLIHF_00393 3.4e-77 ctsR K Belongs to the CtsR family
EAFBLIHF_00394 1.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
EAFBLIHF_00395 1e-148 S Hydrolases of the alpha beta superfamily
EAFBLIHF_00401 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
EAFBLIHF_00402 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_00403 1.3e-276 lysP E amino acid
EAFBLIHF_00404 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
EAFBLIHF_00405 2.7e-120 lssY 3.6.1.27 I phosphatase
EAFBLIHF_00406 7.2e-83 S Threonine/Serine exporter, ThrE
EAFBLIHF_00407 2.1e-132 thrE S Putative threonine/serine exporter
EAFBLIHF_00408 3.5e-31 cspC K Cold shock protein
EAFBLIHF_00409 4.8e-125 sirR K iron dependent repressor
EAFBLIHF_00410 4.1e-167 czcD P cation diffusion facilitator family transporter
EAFBLIHF_00411 7.7e-118 S membrane
EAFBLIHF_00412 1.3e-109 S VIT family
EAFBLIHF_00413 5.5e-83 usp1 T Belongs to the universal stress protein A family
EAFBLIHF_00414 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EAFBLIHF_00415 1.5e-152 glnH ET ABC transporter
EAFBLIHF_00416 2.4e-110 gluC P ABC transporter permease
EAFBLIHF_00417 3.6e-109 glnP P ABC transporter permease
EAFBLIHF_00418 8.3e-221 S CAAX protease self-immunity
EAFBLIHF_00419 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EAFBLIHF_00420 2.9e-57
EAFBLIHF_00421 2.6e-74 merR K MerR HTH family regulatory protein
EAFBLIHF_00422 7.2e-270 lmrB EGP Major facilitator Superfamily
EAFBLIHF_00423 5.8e-124 S Domain of unknown function (DUF4811)
EAFBLIHF_00424 4.3e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EAFBLIHF_00426 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EAFBLIHF_00427 1.5e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
EAFBLIHF_00428 5.3e-189 I Alpha beta
EAFBLIHF_00429 1.9e-281 emrY EGP Major facilitator Superfamily
EAFBLIHF_00430 4.5e-120 ung2 3.2.2.27 L Uracil-DNA glycosylase
EAFBLIHF_00431 9.4e-253 yjjP S Putative threonine/serine exporter
EAFBLIHF_00432 8e-160 mleR K LysR family
EAFBLIHF_00433 1.2e-253 yflS P Sodium:sulfate symporter transmembrane region
EAFBLIHF_00434 5.6e-269 frdC 1.3.5.4 C FAD binding domain
EAFBLIHF_00435 2.1e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EAFBLIHF_00436 2e-310 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
EAFBLIHF_00437 2.5e-161 mleR K LysR family
EAFBLIHF_00438 7.8e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EAFBLIHF_00439 2.7e-207 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
EAFBLIHF_00440 2.3e-300 L PFAM plasmid pRiA4b ORF-3 family protein
EAFBLIHF_00441 2e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
EAFBLIHF_00442 2e-22
EAFBLIHF_00443 3.1e-203 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EAFBLIHF_00444 3e-75
EAFBLIHF_00445 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EAFBLIHF_00446 1.8e-131 ponA V Beta-lactamase enzyme family
EAFBLIHF_00447 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
EAFBLIHF_00448 4.4e-217 uhpT EGP Major facilitator Superfamily
EAFBLIHF_00449 6.4e-262 ytjP 3.5.1.18 E Dipeptidase
EAFBLIHF_00450 1.5e-275 arcD S C4-dicarboxylate anaerobic carrier
EAFBLIHF_00451 3e-181 yfeX P Peroxidase
EAFBLIHF_00452 6.1e-102 lsa S ABC transporter
EAFBLIHF_00453 3.2e-164 lsa S ABC transporter
EAFBLIHF_00454 4.5e-137 I alpha/beta hydrolase fold
EAFBLIHF_00455 1.1e-122 MA20_14895 S Conserved hypothetical protein 698
EAFBLIHF_00456 7.6e-97 S NADPH-dependent FMN reductase
EAFBLIHF_00457 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EAFBLIHF_00458 3e-181 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EAFBLIHF_00459 1.6e-233 mntH P H( )-stimulated, divalent metal cation uptake system
EAFBLIHF_00460 2e-83 Q Methyltransferase
EAFBLIHF_00461 1.4e-116 ktrA P domain protein
EAFBLIHF_00462 8.1e-241 ktrB P Potassium uptake protein
EAFBLIHF_00463 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
EAFBLIHF_00464 3.5e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EAFBLIHF_00465 6.9e-225 G Glycosyl hydrolases family 8
EAFBLIHF_00466 4.8e-246 ydaM M Glycosyl transferase
EAFBLIHF_00467 5.2e-148
EAFBLIHF_00468 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
EAFBLIHF_00469 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EAFBLIHF_00470 2.6e-155 pstA P Phosphate transport system permease protein PstA
EAFBLIHF_00471 1.1e-153 pstC P probably responsible for the translocation of the substrate across the membrane
EAFBLIHF_00472 4.6e-160 pstS P Phosphate
EAFBLIHF_00473 1.6e-134 K Transcriptional regulatory protein, C-terminal domain protein
EAFBLIHF_00474 1.4e-84 L Transposase
EAFBLIHF_00475 3.1e-36 L Transposase
EAFBLIHF_00477 6.2e-193
EAFBLIHF_00478 5.2e-98 2.3.1.128 K acetyltransferase
EAFBLIHF_00479 7.5e-114 manA 5.3.1.8 G mannose-6-phosphate isomerase
EAFBLIHF_00480 2.7e-163 K LysR substrate binding domain
EAFBLIHF_00481 5.2e-209 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
EAFBLIHF_00482 1.2e-54 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EAFBLIHF_00483 1.6e-183
EAFBLIHF_00484 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EAFBLIHF_00485 2e-184 S Phosphotransferase system, EIIC
EAFBLIHF_00486 5.6e-39 L PFAM Integrase catalytic region
EAFBLIHF_00487 9e-77 L PFAM Integrase catalytic region
EAFBLIHF_00489 7.7e-160 metQ_4 P Belongs to the nlpA lipoprotein family
EAFBLIHF_00490 1.5e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EAFBLIHF_00491 6.9e-127 O Zinc-dependent metalloprotease
EAFBLIHF_00492 1.9e-115 S Membrane
EAFBLIHF_00493 1.9e-200 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
EAFBLIHF_00494 5.7e-174 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
EAFBLIHF_00495 1.6e-271 L PFAM Integrase catalytic region
EAFBLIHF_00496 3.5e-238 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EAFBLIHF_00497 2.5e-39 S Cytochrome B5
EAFBLIHF_00498 2e-27
EAFBLIHF_00499 3.4e-82 S Domain of unknown function (DUF4767)
EAFBLIHF_00500 3.3e-13
EAFBLIHF_00501 1.4e-212 cytX U Belongs to the purine-cytosine permease (2.A.39) family
EAFBLIHF_00502 1.9e-97 wecD3 K PFAM GCN5-related N-acetyltransferase
EAFBLIHF_00503 7.3e-80
EAFBLIHF_00504 4.2e-123 M Lysin motif
EAFBLIHF_00505 7.1e-201 EGP Major facilitator Superfamily
EAFBLIHF_00506 1.2e-85 ywlG S Belongs to the UPF0340 family
EAFBLIHF_00507 3.2e-161 spoU 2.1.1.185 J Methyltransferase
EAFBLIHF_00508 1.3e-224 oxlT P Major Facilitator Superfamily
EAFBLIHF_00509 3.8e-237 L Belongs to the 'phage' integrase family
EAFBLIHF_00510 1.1e-33 S Domain of unknown function (DUF3173)
EAFBLIHF_00512 0.0
EAFBLIHF_00513 1.4e-172
EAFBLIHF_00514 2.1e-85 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EAFBLIHF_00515 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
EAFBLIHF_00516 1.6e-260 G Major Facilitator Superfamily
EAFBLIHF_00517 4.2e-49 V DNA modification
EAFBLIHF_00518 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EAFBLIHF_00520 1.7e-226 S cog cog1373
EAFBLIHF_00521 3.3e-177 coaA 2.7.1.33 F Pantothenic acid kinase
EAFBLIHF_00522 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EAFBLIHF_00523 7e-161 EG EamA-like transporter family
EAFBLIHF_00524 5e-27 Q pyridine nucleotide-disulphide oxidoreductase
EAFBLIHF_00525 1.5e-230 L transposase, IS605 OrfB family
EAFBLIHF_00526 9.6e-61 L PFAM transposase IS200-family protein
EAFBLIHF_00527 0.0 helD 3.6.4.12 L DNA helicase
EAFBLIHF_00528 3.6e-117 dedA S SNARE associated Golgi protein
EAFBLIHF_00529 5e-127 3.1.3.73 G phosphoglycerate mutase
EAFBLIHF_00530 1.3e-235 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EAFBLIHF_00531 6.6e-35 S Transglycosylase associated protein
EAFBLIHF_00533 1.5e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAFBLIHF_00534 9.5e-239 V domain protein
EAFBLIHF_00535 1.6e-94 K Transcriptional regulator (TetR family)
EAFBLIHF_00536 3.4e-39 pspC KT positive regulation of macromolecule biosynthetic process
EAFBLIHF_00537 2e-152
EAFBLIHF_00538 3.1e-17 3.2.1.14 GH18
EAFBLIHF_00539 1.5e-82 zur P Belongs to the Fur family
EAFBLIHF_00540 5.2e-104 gmk2 2.7.4.8 F Guanylate kinase
EAFBLIHF_00541 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
EAFBLIHF_00542 1.1e-256 yfnA E Amino Acid
EAFBLIHF_00543 3.9e-232 EGP Sugar (and other) transporter
EAFBLIHF_00544 1e-232
EAFBLIHF_00545 2.3e-209 potD P ABC transporter
EAFBLIHF_00546 4.9e-140 potC P ABC transporter permease
EAFBLIHF_00547 4.5e-146 potB P ABC transporter permease
EAFBLIHF_00548 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EAFBLIHF_00549 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EAFBLIHF_00550 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
EAFBLIHF_00551 0.0 pacL 3.6.3.8 P P-type ATPase
EAFBLIHF_00552 2.6e-85 dps P Belongs to the Dps family
EAFBLIHF_00553 3e-254 yagE E amino acid
EAFBLIHF_00554 2.5e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant
EAFBLIHF_00555 5.7e-30 3.6.4.12 S PD-(D/E)XK nuclease family transposase
EAFBLIHF_00556 2e-25 L Helix-turn-helix domain
EAFBLIHF_00557 5.1e-87 L Helix-turn-helix domain
EAFBLIHF_00558 1e-127 L hmm pf00665
EAFBLIHF_00559 4.7e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
EAFBLIHF_00560 2.1e-182 iunH2 3.2.2.1 F nucleoside hydrolase
EAFBLIHF_00561 2.5e-138 IQ KR domain
EAFBLIHF_00562 6.6e-134 S membrane transporter protein
EAFBLIHF_00563 1.9e-98 S ABC-type cobalt transport system, permease component
EAFBLIHF_00564 1.6e-260 cbiO1 S ABC transporter, ATP-binding protein
EAFBLIHF_00565 2.6e-115 P Cobalt transport protein
EAFBLIHF_00566 1.6e-52 yvlA
EAFBLIHF_00567 0.0 yjcE P Sodium proton antiporter
EAFBLIHF_00568 2.2e-52 ypaA S Protein of unknown function (DUF1304)
EAFBLIHF_00569 5.9e-168 D Alpha beta
EAFBLIHF_00570 1e-72 K Transcriptional regulator
EAFBLIHF_00571 2.6e-163
EAFBLIHF_00572 8.8e-184 1.6.5.5 C Zinc-binding dehydrogenase
EAFBLIHF_00573 3.5e-258 G PTS system Galactitol-specific IIC component
EAFBLIHF_00574 8.2e-213 EGP Major facilitator Superfamily
EAFBLIHF_00575 1.5e-137 V ABC transporter
EAFBLIHF_00576 4.5e-121
EAFBLIHF_00577 5.2e-14
EAFBLIHF_00578 1.9e-63
EAFBLIHF_00579 3.9e-195 lplA 6.3.1.20 H Lipoate-protein ligase
EAFBLIHF_00580 5.1e-81 uspA T universal stress protein
EAFBLIHF_00581 0.0 tetP J elongation factor G
EAFBLIHF_00582 2.1e-168 GK ROK family
EAFBLIHF_00583 7.2e-245 brnQ U Component of the transport system for branched-chain amino acids
EAFBLIHF_00584 1.3e-81 tlpA2 L Transposase IS200 like
EAFBLIHF_00585 4.9e-240 L transposase, IS605 OrfB family
EAFBLIHF_00586 7e-141 aroD S Serine hydrolase (FSH1)
EAFBLIHF_00587 7.2e-245 yagE E amino acid
EAFBLIHF_00588 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
EAFBLIHF_00589 4.3e-135 gntR K UbiC transcription regulator-associated domain protein
EAFBLIHF_00590 4.2e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAFBLIHF_00591 1.2e-285 pipD E Dipeptidase
EAFBLIHF_00592 0.0 yfiC V ABC transporter
EAFBLIHF_00593 4.8e-310 lmrA V ABC transporter, ATP-binding protein
EAFBLIHF_00594 2.9e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAFBLIHF_00595 1.2e-81 S ECF transporter, substrate-specific component
EAFBLIHF_00596 2.5e-62 S Domain of unknown function (DUF4430)
EAFBLIHF_00597 5.9e-194 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
EAFBLIHF_00598 7.3e-132 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EAFBLIHF_00599 5.4e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
EAFBLIHF_00600 4.8e-137 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EAFBLIHF_00601 1.6e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
EAFBLIHF_00602 3.4e-252 hemL 5.4.3.8 H Aminotransferase class-III
EAFBLIHF_00603 2.4e-181 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
EAFBLIHF_00604 2.3e-170 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EAFBLIHF_00605 1.4e-237 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EAFBLIHF_00606 3.2e-80 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
EAFBLIHF_00607 3.3e-283 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
EAFBLIHF_00608 2e-149 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
EAFBLIHF_00609 4.4e-118 cbiQ P Cobalt transport protein
EAFBLIHF_00610 8.7e-53 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
EAFBLIHF_00611 2.4e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
EAFBLIHF_00612 6e-126 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
EAFBLIHF_00613 2.3e-147 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
EAFBLIHF_00614 3e-262 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
EAFBLIHF_00615 2.5e-138 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
EAFBLIHF_00616 5.7e-132 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
EAFBLIHF_00617 8.2e-196 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
EAFBLIHF_00618 4.8e-137 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
EAFBLIHF_00619 4.9e-99 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
EAFBLIHF_00620 1e-110 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
EAFBLIHF_00621 1.6e-208 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EAFBLIHF_00622 9.2e-124 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
EAFBLIHF_00623 5.7e-180 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EAFBLIHF_00624 4.1e-264 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
EAFBLIHF_00625 1.5e-208 cobD 4.1.1.81 E Aminotransferase class I and II
EAFBLIHF_00626 4.7e-190 L PFAM Integrase catalytic region
EAFBLIHF_00627 1.7e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
EAFBLIHF_00628 7.1e-158 XK27_04590 S NADPH-dependent FMN reductase
EAFBLIHF_00629 1e-78 fld C Flavodoxin
EAFBLIHF_00630 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
EAFBLIHF_00631 3.1e-93 P Cadmium resistance transporter
EAFBLIHF_00632 3.1e-121 pgm1 3.1.3.73 G phosphoglycerate mutase
EAFBLIHF_00633 1.9e-149 3.1.3.48 T Pfam:Y_phosphatase3C
EAFBLIHF_00634 5.5e-56 pduU E BMC
EAFBLIHF_00635 2.2e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAFBLIHF_00636 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
EAFBLIHF_00637 3.1e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
EAFBLIHF_00638 7.4e-80 pduO S Haem-degrading
EAFBLIHF_00639 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
EAFBLIHF_00640 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
EAFBLIHF_00641 6.4e-90 S Putative propanediol utilisation
EAFBLIHF_00642 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
EAFBLIHF_00643 7.6e-43 pduA_4 CQ BMC
EAFBLIHF_00644 5.1e-75 pduK CQ BMC
EAFBLIHF_00645 1.7e-60 pduH S Dehydratase medium subunit
EAFBLIHF_00646 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
EAFBLIHF_00647 2.1e-80 pduE 4.2.1.28 Q Dehydratase small subunit
EAFBLIHF_00648 3.8e-128 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
EAFBLIHF_00649 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
EAFBLIHF_00650 2.7e-134 pduB E BMC
EAFBLIHF_00651 6.2e-42 pduA_4 CQ BMC
EAFBLIHF_00652 3e-201 K helix_turn_helix, arabinose operon control protein
EAFBLIHF_00653 4.1e-150 eutJ E Hsp70 protein
EAFBLIHF_00654 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EAFBLIHF_00655 9e-167
EAFBLIHF_00656 3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
EAFBLIHF_00657 1.8e-177 S AI-2E family transporter
EAFBLIHF_00658 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
EAFBLIHF_00659 1.7e-78 yybA 2.3.1.57 K Transcriptional regulator
EAFBLIHF_00660 6.1e-91 M1-874 K Domain of unknown function (DUF1836)
EAFBLIHF_00661 7.2e-92 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
EAFBLIHF_00662 4.7e-157 ypdB V (ABC) transporter
EAFBLIHF_00663 1.1e-242 yhdP S Transporter associated domain
EAFBLIHF_00664 9.9e-85 nrdI F Belongs to the NrdI family
EAFBLIHF_00665 1.4e-74 S 3-demethylubiquinone-9 3-methyltransferase
EAFBLIHF_00666 3.6e-194 yeaN P Transporter, major facilitator family protein
EAFBLIHF_00667 5.7e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EAFBLIHF_00668 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EAFBLIHF_00669 1.1e-40
EAFBLIHF_00670 0.0 lacS G Transporter
EAFBLIHF_00671 1.5e-80 uspA T universal stress protein
EAFBLIHF_00672 1.5e-80 K AsnC family
EAFBLIHF_00673 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EAFBLIHF_00674 1.7e-103 dedA 3.1.3.1 S SNARE associated Golgi protein
EAFBLIHF_00675 9.8e-82 L transposase and inactivated derivatives, IS30 family
EAFBLIHF_00676 2.8e-108 tra L Transposase and inactivated derivatives, IS30 family
EAFBLIHF_00677 3.7e-182 galR K Transcriptional regulator
EAFBLIHF_00678 1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EAFBLIHF_00679 1.2e-227 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EAFBLIHF_00680 2.2e-187 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
EAFBLIHF_00681 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
EAFBLIHF_00682 4.3e-94 yxkA S Phosphatidylethanolamine-binding protein
EAFBLIHF_00683 9.1e-36
EAFBLIHF_00684 9.1e-53
EAFBLIHF_00685 4.6e-205
EAFBLIHF_00686 1.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EAFBLIHF_00687 1.8e-136 pnuC H nicotinamide mononucleotide transporter
EAFBLIHF_00688 9.9e-160 ytbE 1.1.1.346 S Aldo keto reductase
EAFBLIHF_00689 3.4e-126 K response regulator
EAFBLIHF_00690 8.7e-184 T Histidine kinase-like ATPases
EAFBLIHF_00691 6.8e-136 macB2 V ABC transporter, ATP-binding protein
EAFBLIHF_00692 0.0 ysaB V FtsX-like permease family
EAFBLIHF_00693 7.4e-160 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
EAFBLIHF_00694 1.8e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EAFBLIHF_00695 2.2e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAFBLIHF_00696 3.9e-199 EGP Major facilitator Superfamily
EAFBLIHF_00697 1.5e-91 ymdB S Macro domain protein
EAFBLIHF_00698 3.9e-113 K Helix-turn-helix XRE-family like proteins
EAFBLIHF_00699 0.0 pepO 3.4.24.71 O Peptidase family M13
EAFBLIHF_00700 3.6e-48
EAFBLIHF_00701 5.6e-247 S Putative metallopeptidase domain
EAFBLIHF_00702 1.4e-209 3.1.3.1 S associated with various cellular activities
EAFBLIHF_00703 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
EAFBLIHF_00704 1.4e-65 yeaO S Protein of unknown function, DUF488
EAFBLIHF_00706 6e-123 yrkL S Flavodoxin-like fold
EAFBLIHF_00707 1.6e-54
EAFBLIHF_00708 3.3e-18 S Domain of unknown function (DUF4767)
EAFBLIHF_00709 2.4e-141 3.6.4.12 S PD-(D/E)XK nuclease family transposase
EAFBLIHF_00710 1.1e-49
EAFBLIHF_00711 1.4e-206 nrnB S DHHA1 domain
EAFBLIHF_00712 1.3e-232 S Uncharacterized protein conserved in bacteria (DUF2325)
EAFBLIHF_00713 9.9e-250 brnQ U Component of the transport system for branched-chain amino acids
EAFBLIHF_00714 1.5e-106 NU mannosyl-glycoprotein
EAFBLIHF_00715 1.8e-147 S Putative ABC-transporter type IV
EAFBLIHF_00716 4.4e-275 S ABC transporter, ATP-binding protein
EAFBLIHF_00717 2.9e-11
EAFBLIHF_00719 1e-108 S Protein of unknown function (DUF3278)
EAFBLIHF_00720 7.8e-14 relB L RelB antitoxin
EAFBLIHF_00722 1e-78 M PFAM NLP P60 protein
EAFBLIHF_00723 9.8e-183 ABC-SBP S ABC transporter
EAFBLIHF_00724 8.6e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
EAFBLIHF_00725 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
EAFBLIHF_00726 5.1e-96 P Cadmium resistance transporter
EAFBLIHF_00727 5.2e-56 K Transcriptional regulator, ArsR family
EAFBLIHF_00728 1e-240 mepA V MATE efflux family protein
EAFBLIHF_00729 1.5e-55 trxA O Belongs to the thioredoxin family
EAFBLIHF_00730 2.3e-131 terC P membrane
EAFBLIHF_00731 7.4e-177 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EAFBLIHF_00732 9.7e-169 corA P CorA-like Mg2+ transporter protein
EAFBLIHF_00733 2.6e-285 pipD E Dipeptidase
EAFBLIHF_00734 1.9e-242 pbuX F xanthine permease
EAFBLIHF_00735 1.9e-248 nhaC C Na H antiporter NhaC
EAFBLIHF_00736 7.1e-250 hisS 6.1.1.21 J histidyl-tRNA synthetase
EAFBLIHF_00737 2.5e-97 S Family of unknown function (DUF5449)
EAFBLIHF_00738 1.7e-184 4.1.1.22 H Histidine carboxylase PI chain
EAFBLIHF_00739 5.5e-267 aaxC E Arginine ornithine antiporter
EAFBLIHF_00740 4.2e-71 S Uncharacterised protein family (UPF0236)
EAFBLIHF_00741 3.8e-176 S Uncharacterised protein family (UPF0236)
EAFBLIHF_00742 9.6e-286 S C4-dicarboxylate anaerobic carrier
EAFBLIHF_00743 6.5e-127 pgm3 3.1.3.73 G phosphoglycerate mutase family
EAFBLIHF_00744 1.3e-41
EAFBLIHF_00745 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EAFBLIHF_00746 1.1e-211 gldA 1.1.1.6 C dehydrogenase
EAFBLIHF_00747 7e-126 S Alpha beta hydrolase
EAFBLIHF_00748 7.1e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EAFBLIHF_00749 1.5e-103
EAFBLIHF_00751 1.4e-124 yciB M ErfK YbiS YcfS YnhG
EAFBLIHF_00752 8.8e-96 S Putative peptidoglycan binding domain
EAFBLIHF_00753 7.7e-44 S Putative peptidoglycan binding domain
EAFBLIHF_00754 9.9e-112 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
EAFBLIHF_00755 2.4e-89
EAFBLIHF_00756 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
EAFBLIHF_00757 5.1e-218 yttB EGP Major facilitator Superfamily
EAFBLIHF_00758 4.3e-104
EAFBLIHF_00759 1e-24
EAFBLIHF_00760 5.5e-175 scrR K Transcriptional regulator, LacI family
EAFBLIHF_00761 2.5e-255 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EAFBLIHF_00762 2.4e-50 czrA K Transcriptional regulator, ArsR family
EAFBLIHF_00763 2.1e-38
EAFBLIHF_00764 0.0 yhcA V ABC transporter, ATP-binding protein
EAFBLIHF_00765 9.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
EAFBLIHF_00766 4e-174 hrtB V ABC transporter permease
EAFBLIHF_00767 1.9e-89 ygfC K transcriptional regulator (TetR family)
EAFBLIHF_00768 1.3e-190 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
EAFBLIHF_00769 1e-290 mntH P H( )-stimulated, divalent metal cation uptake system
EAFBLIHF_00770 5.5e-36
EAFBLIHF_00771 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EAFBLIHF_00773 2.7e-92 yxiO S Vacuole effluxer Atg22 like
EAFBLIHF_00774 4.9e-111 yxiO S Vacuole effluxer Atg22 like
EAFBLIHF_00775 9.2e-258 npp S type I phosphodiesterase nucleotide pyrophosphatase
EAFBLIHF_00776 1.4e-240 E amino acid
EAFBLIHF_00777 3.2e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAFBLIHF_00779 3.5e-28 WQ51_00220 K Helix-turn-helix XRE-family like proteins
EAFBLIHF_00780 4.2e-15 S Protein of unknown function (DUF3278)
EAFBLIHF_00781 4.2e-222 yxjG_1 E methionine synthase, vitamin-B12 independent
EAFBLIHF_00782 1.6e-41 S Cytochrome B5
EAFBLIHF_00783 5.4e-09 S Cytochrome B5
EAFBLIHF_00784 1.8e-39 S Cytochrome B5
EAFBLIHF_00785 2.4e-77 elaA S Gnat family
EAFBLIHF_00786 1.4e-121 GM NmrA-like family
EAFBLIHF_00787 2.5e-52 hxlR K Transcriptional regulator, HxlR family
EAFBLIHF_00788 6.7e-110 XK27_02070 S Nitroreductase family
EAFBLIHF_00789 6.2e-84 K Transcriptional regulator, HxlR family
EAFBLIHF_00790 8.5e-243
EAFBLIHF_00791 2e-211 EGP Major facilitator Superfamily
EAFBLIHF_00792 4.7e-257 pepC 3.4.22.40 E aminopeptidase
EAFBLIHF_00793 9.6e-115 ylbE GM NAD dependent epimerase dehydratase family protein
EAFBLIHF_00794 0.0 pepN 3.4.11.2 E aminopeptidase
EAFBLIHF_00795 6.3e-94 folT S ECF transporter, substrate-specific component
EAFBLIHF_00796 1.7e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
EAFBLIHF_00797 6e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
EAFBLIHF_00798 9.8e-126 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
EAFBLIHF_00799 1.1e-206 2.7.7.65 T GGDEF domain
EAFBLIHF_00800 7.5e-91
EAFBLIHF_00801 4e-256 pgaC GT2 M Glycosyl transferase
EAFBLIHF_00802 1.7e-159 T EAL domain
EAFBLIHF_00803 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_00804 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
EAFBLIHF_00805 1.1e-64 yneR
EAFBLIHF_00806 1.6e-114 GM NAD(P)H-binding
EAFBLIHF_00807 2.1e-189 S membrane
EAFBLIHF_00808 1.8e-104 K Transcriptional regulator C-terminal region
EAFBLIHF_00809 2.4e-164 akr5f 1.1.1.346 S reductase
EAFBLIHF_00810 2.8e-157 K Transcriptional regulator
EAFBLIHF_00811 6.1e-185 ansA 3.5.1.1 EJ L-asparaginase, type I
EAFBLIHF_00812 1e-155 ypuA S Protein of unknown function (DUF1002)
EAFBLIHF_00813 1.1e-228 aadAT EK Aminotransferase, class I
EAFBLIHF_00814 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EAFBLIHF_00815 9.2e-155 tesE Q hydratase
EAFBLIHF_00816 4e-133 S Alpha beta hydrolase
EAFBLIHF_00818 2.6e-89 lacA S transferase hexapeptide repeat
EAFBLIHF_00819 2.1e-160 K Transcriptional regulator
EAFBLIHF_00820 1.2e-88 C Flavodoxin
EAFBLIHF_00821 6.3e-11 S Oxidoreductase, aldo keto reductase family protein
EAFBLIHF_00822 8.6e-56 yphJ 4.1.1.44 S decarboxylase
EAFBLIHF_00823 5.5e-102 M Protein of unknown function (DUF3737)
EAFBLIHF_00824 2.3e-228 4.4.1.8 E Aminotransferase, class I
EAFBLIHF_00825 4.7e-163 mleP3 S Membrane transport protein
EAFBLIHF_00826 4.4e-126 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
EAFBLIHF_00828 1.1e-189 L PFAM Integrase catalytic region
EAFBLIHF_00829 1.8e-40 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
EAFBLIHF_00830 3e-24
EAFBLIHF_00831 1.1e-19 relB L Addiction module antitoxin, RelB DinJ family
EAFBLIHF_00832 7.5e-91 XK27_08850 J Aminoacyl-tRNA editing domain
EAFBLIHF_00833 1e-56 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
EAFBLIHF_00834 7.7e-199 V Beta-lactamase
EAFBLIHF_00835 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EAFBLIHF_00836 1.7e-122 yhiD S MgtC family
EAFBLIHF_00837 4e-121 S GyrI-like small molecule binding domain
EAFBLIHF_00839 6.1e-125 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
EAFBLIHF_00840 3.2e-50 azlD E Branched-chain amino acid transport
EAFBLIHF_00841 2e-121 azlC E azaleucine resistance protein AzlC
EAFBLIHF_00842 2.6e-266 K Aminotransferase class I and II
EAFBLIHF_00843 1.9e-305 S amidohydrolase
EAFBLIHF_00844 1.6e-165 S reductase
EAFBLIHF_00845 1.6e-93 2.3.1.183 M Acetyltransferase GNAT family
EAFBLIHF_00846 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EAFBLIHF_00847 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
EAFBLIHF_00848 4.8e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAFBLIHF_00849 0.0 asnB 6.3.5.4 E Asparagine synthase
EAFBLIHF_00850 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EAFBLIHF_00851 7.1e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EAFBLIHF_00852 4.1e-136 jag S R3H domain protein
EAFBLIHF_00853 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EAFBLIHF_00854 1.2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EAFBLIHF_00855 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
EAFBLIHF_00856 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EAFBLIHF_00857 2.9e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EAFBLIHF_00858 1.7e-34 yaaA S S4 domain protein YaaA
EAFBLIHF_00859 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EAFBLIHF_00860 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EAFBLIHF_00861 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EAFBLIHF_00862 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
EAFBLIHF_00863 7.5e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EAFBLIHF_00864 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EAFBLIHF_00865 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EAFBLIHF_00866 2e-74 rplI J Binds to the 23S rRNA
EAFBLIHF_00867 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EAFBLIHF_00868 6.9e-207 yttB EGP Major facilitator Superfamily
EAFBLIHF_00869 1.5e-60
EAFBLIHF_00870 2.8e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
EAFBLIHF_00871 3.1e-101 K DNA-binding helix-turn-helix protein
EAFBLIHF_00873 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
EAFBLIHF_00874 0.0 lmrA 3.6.3.44 V ABC transporter
EAFBLIHF_00876 3.1e-130 K response regulator
EAFBLIHF_00877 0.0 vicK 2.7.13.3 T Histidine kinase
EAFBLIHF_00878 4.9e-251 yycH S YycH protein
EAFBLIHF_00879 2.6e-152 yycI S YycH protein
EAFBLIHF_00880 1.2e-154 vicX 3.1.26.11 S domain protein
EAFBLIHF_00881 6.4e-219 htrA 3.4.21.107 O serine protease
EAFBLIHF_00882 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
EAFBLIHF_00883 8.2e-182 ABC-SBP S ABC transporter
EAFBLIHF_00884 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EAFBLIHF_00886 2.9e-96 S reductase
EAFBLIHF_00887 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
EAFBLIHF_00888 7.5e-155 glcU U sugar transport
EAFBLIHF_00889 6.5e-150 E Glyoxalase-like domain
EAFBLIHF_00890 4.1e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EAFBLIHF_00891 2.1e-260 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
EAFBLIHF_00892 1.4e-145 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAFBLIHF_00893 2e-129 V ABC transporter
EAFBLIHF_00894 2.8e-219 bacI V MacB-like periplasmic core domain
EAFBLIHF_00896 2.5e-20
EAFBLIHF_00897 2.5e-269 S Putative peptidoglycan binding domain
EAFBLIHF_00900 1.3e-28 2.7.13.3 T GHKL domain
EAFBLIHF_00901 5e-75 osmC O OsmC-like protein
EAFBLIHF_00902 3.2e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAFBLIHF_00903 1.5e-222 patA 2.6.1.1 E Aminotransferase
EAFBLIHF_00904 2.7e-32
EAFBLIHF_00905 0.0 clpL O associated with various cellular activities
EAFBLIHF_00907 2.3e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
EAFBLIHF_00908 2.4e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAFBLIHF_00909 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EAFBLIHF_00910 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EAFBLIHF_00911 7.1e-175 malR K Transcriptional regulator, LacI family
EAFBLIHF_00912 2.1e-216 phbA 2.3.1.9 I Belongs to the thiolase family
EAFBLIHF_00913 8.1e-257 malT G Major Facilitator
EAFBLIHF_00914 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
EAFBLIHF_00915 1.9e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
EAFBLIHF_00916 3e-72
EAFBLIHF_00917 8.2e-87 2.7.6.5 T Region found in RelA / SpoT proteins
EAFBLIHF_00918 1.9e-118 K response regulator
EAFBLIHF_00919 2.4e-226 sptS 2.7.13.3 T Histidine kinase
EAFBLIHF_00920 1.3e-218 yfeO P Voltage gated chloride channel
EAFBLIHF_00921 1.1e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
EAFBLIHF_00922 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_00923 3.5e-137 puuD S peptidase C26
EAFBLIHF_00924 9.2e-169 yvgN C Aldo keto reductase
EAFBLIHF_00925 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
EAFBLIHF_00926 3e-87 hmpT S ECF-type riboflavin transporter, S component
EAFBLIHF_00927 5.3e-264 nox C NADH oxidase
EAFBLIHF_00928 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EAFBLIHF_00929 1.1e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EAFBLIHF_00930 2.6e-90
EAFBLIHF_00931 2.6e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EAFBLIHF_00933 4e-242 L transposase, IS605 OrfB family
EAFBLIHF_00934 1e-81 tlpA2 L Transposase IS200 like
EAFBLIHF_00935 6.4e-139 puuD S peptidase C26
EAFBLIHF_00936 5.5e-248 steT_1 E amino acid
EAFBLIHF_00937 3.3e-13 K Transcriptional regulator, TetR family
EAFBLIHF_00938 1.7e-73 K Transcriptional regulator, TetR family
EAFBLIHF_00939 2.2e-72
EAFBLIHF_00940 2e-275 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EAFBLIHF_00941 2.7e-277 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
EAFBLIHF_00942 0.0 M domain protein
EAFBLIHF_00943 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
EAFBLIHF_00944 2.3e-267 G Major Facilitator
EAFBLIHF_00945 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EAFBLIHF_00946 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EAFBLIHF_00947 5.5e-261 G Major Facilitator
EAFBLIHF_00948 1.5e-183 K Transcriptional regulator, LacI family
EAFBLIHF_00949 1.3e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAFBLIHF_00951 2.9e-102 nqr 1.5.1.36 S reductase
EAFBLIHF_00952 7.4e-204 XK27_09615 S reductase
EAFBLIHF_00953 1.9e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EAFBLIHF_00954 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_00955 2.8e-212 fhaB M Rib/alpha-like repeat
EAFBLIHF_00956 8e-74 L PFAM Integrase catalytic region
EAFBLIHF_00957 6.8e-297 fhaB M Rib/alpha-like repeat
EAFBLIHF_00958 2.2e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EAFBLIHF_00959 1e-265 glnP P ABC transporter
EAFBLIHF_00960 8.5e-139 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EAFBLIHF_00961 7.7e-223 cycA E Amino acid permease
EAFBLIHF_00962 1e-218 nupG F Nucleoside transporter
EAFBLIHF_00963 2.7e-171 rihC 3.2.2.1 F Nucleoside
EAFBLIHF_00964 1.5e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
EAFBLIHF_00965 5.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
EAFBLIHF_00966 7.4e-151 noc K Belongs to the ParB family
EAFBLIHF_00967 3.6e-140 soj D Sporulation initiation inhibitor
EAFBLIHF_00968 5.9e-155 spo0J K Belongs to the ParB family
EAFBLIHF_00969 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
EAFBLIHF_00970 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EAFBLIHF_00971 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
EAFBLIHF_00972 4.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EAFBLIHF_00973 1.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EAFBLIHF_00974 9.6e-239 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
EAFBLIHF_00975 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
EAFBLIHF_00976 3.9e-173 deoR K sugar-binding domain protein
EAFBLIHF_00977 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EAFBLIHF_00978 3.8e-125 K response regulator
EAFBLIHF_00979 2e-203 hpk31 2.7.13.3 T Histidine kinase
EAFBLIHF_00980 9.7e-137 azlC E AzlC protein
EAFBLIHF_00981 1.6e-52 azlD S branched-chain amino acid
EAFBLIHF_00982 2.9e-115 K DNA-binding transcription factor activity
EAFBLIHF_00983 4.4e-16 K LysR substrate binding domain
EAFBLIHF_00984 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EAFBLIHF_00985 3e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EAFBLIHF_00986 1.1e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EAFBLIHF_00987 4.6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EAFBLIHF_00988 7.9e-117 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EAFBLIHF_00989 1.6e-117 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
EAFBLIHF_00990 2.9e-237 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
EAFBLIHF_00991 1.1e-173 K AI-2E family transporter
EAFBLIHF_00992 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EAFBLIHF_00993 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EAFBLIHF_00994 3.5e-134 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
EAFBLIHF_00995 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EAFBLIHF_00996 7.8e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EAFBLIHF_00997 1.1e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EAFBLIHF_00998 6.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EAFBLIHF_00999 1.8e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAFBLIHF_01000 4.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAFBLIHF_01001 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAFBLIHF_01002 2.8e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EAFBLIHF_01003 6.6e-198 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EAFBLIHF_01004 1.6e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EAFBLIHF_01005 2.2e-298 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EAFBLIHF_01006 1.2e-246 purD 6.3.4.13 F Belongs to the GARS family
EAFBLIHF_01007 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EAFBLIHF_01008 3.2e-176
EAFBLIHF_01009 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EAFBLIHF_01010 6.8e-270 L Transposase IS66 family
EAFBLIHF_01011 2.6e-11 L Transposase IS66 family
EAFBLIHF_01012 2.3e-65 XK27_01125 L PFAM IS66 Orf2 family protein
EAFBLIHF_01014 8.7e-116 lssY 3.6.1.27 I Acid phosphatase homologues
EAFBLIHF_01015 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
EAFBLIHF_01016 4.2e-231 clcA_2 P Chloride transporter, ClC family
EAFBLIHF_01017 6.5e-119 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EAFBLIHF_01018 4.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EAFBLIHF_01019 4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EAFBLIHF_01020 1.6e-51
EAFBLIHF_01021 0.0 S SEC-C Motif Domain Protein
EAFBLIHF_01022 1.7e-295 L Transposase IS66 family
EAFBLIHF_01023 1.1e-52 XK27_01125 L PFAM IS66 Orf2 family protein
EAFBLIHF_01025 5.9e-88 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
EAFBLIHF_01026 1.2e-76
EAFBLIHF_01027 1.2e-180
EAFBLIHF_01028 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_01029 2.8e-44 L transposase and inactivated derivatives, IS30 family
EAFBLIHF_01030 5.6e-126 L PFAM Integrase catalytic region
EAFBLIHF_01031 1.1e-43 M Leucine-rich repeat (LRR) protein
EAFBLIHF_01032 2.9e-257 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_01033 7.2e-81 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
EAFBLIHF_01034 9.6e-75 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
EAFBLIHF_01035 5.9e-120 L PFAM Integrase catalytic region
EAFBLIHF_01036 8.5e-174 fecB P Periplasmic binding protein
EAFBLIHF_01037 6.3e-137 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
EAFBLIHF_01038 1.8e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAFBLIHF_01039 3.6e-76 S Flavodoxin
EAFBLIHF_01040 2.5e-64 moaE 2.8.1.12 H MoaE protein
EAFBLIHF_01041 4.9e-35 moaD 2.8.1.12 H ThiS family
EAFBLIHF_01042 3.9e-218 narK P Transporter, major facilitator family protein
EAFBLIHF_01043 1.7e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
EAFBLIHF_01044 1.4e-181
EAFBLIHF_01045 1.6e-18
EAFBLIHF_01046 2.6e-115 nreC K PFAM regulatory protein LuxR
EAFBLIHF_01047 5.1e-190 comP 2.7.13.3 F Sensor histidine kinase
EAFBLIHF_01048 5.1e-44
EAFBLIHF_01049 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EAFBLIHF_01050 7.9e-85 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
EAFBLIHF_01051 3.2e-228 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
EAFBLIHF_01052 3.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
EAFBLIHF_01053 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
EAFBLIHF_01054 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EAFBLIHF_01055 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
EAFBLIHF_01056 7.9e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
EAFBLIHF_01057 2.5e-129 narI 1.7.5.1 C Nitrate reductase
EAFBLIHF_01058 2.6e-55 L Transposase
EAFBLIHF_01059 1.6e-160 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EAFBLIHF_01060 2.2e-311 L Transposase
EAFBLIHF_01061 2.9e-154 EG EamA-like transporter family
EAFBLIHF_01062 2.5e-118 L Integrase
EAFBLIHF_01063 1.7e-159 rssA S Phospholipase, patatin family
EAFBLIHF_01064 4.8e-125 L transposase activity
EAFBLIHF_01065 4.5e-114 L PFAM Integrase catalytic region
EAFBLIHF_01066 4.6e-202 xerS L Belongs to the 'phage' integrase family
EAFBLIHF_01068 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EAFBLIHF_01069 4.2e-77 marR K Transcriptional regulator, MarR family
EAFBLIHF_01070 3.8e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EAFBLIHF_01071 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAFBLIHF_01072 3.3e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EAFBLIHF_01073 1.3e-131 IQ reductase
EAFBLIHF_01074 5.6e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EAFBLIHF_01075 2.1e-76 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EAFBLIHF_01076 1e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EAFBLIHF_01077 3.2e-261 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
EAFBLIHF_01078 6.5e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EAFBLIHF_01079 1.6e-140 accA 2.1.3.15, 6.4.1.2 I alpha subunit
EAFBLIHF_01080 4.9e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EAFBLIHF_01089 3.6e-55
EAFBLIHF_01090 2.3e-116 frnE Q DSBA-like thioredoxin domain
EAFBLIHF_01091 5e-167 I alpha/beta hydrolase fold
EAFBLIHF_01092 5.7e-85 L PFAM transposase IS200-family protein
EAFBLIHF_01095 5e-22 S Phage derived protein Gp49-like (DUF891)
EAFBLIHF_01096 1.7e-47 L Belongs to the 'phage' integrase family
EAFBLIHF_01098 2.3e-36 S Lipopolysaccharide assembly protein A domain
EAFBLIHF_01099 3.7e-159 3.1.3.102, 3.1.3.104 S hydrolase
EAFBLIHF_01100 1.2e-90 ntd 2.4.2.6 F Nucleoside
EAFBLIHF_01101 7.5e-21
EAFBLIHF_01102 1.7e-167 S Alpha/beta hydrolase of unknown function (DUF915)
EAFBLIHF_01103 4.3e-115 yviA S Protein of unknown function (DUF421)
EAFBLIHF_01104 1.9e-29 S Protein of unknown function (DUF3290)
EAFBLIHF_01105 2e-28 S Protein of unknown function (DUF3290)
EAFBLIHF_01106 3.5e-42 ybaN S Protein of unknown function (DUF454)
EAFBLIHF_01107 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_01108 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAFBLIHF_01109 7.7e-160 endA V DNA/RNA non-specific endonuclease
EAFBLIHF_01110 3.5e-255 yifK E Amino acid permease
EAFBLIHF_01112 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EAFBLIHF_01113 2e-233 N Uncharacterized conserved protein (DUF2075)
EAFBLIHF_01114 6.1e-123 S SNARE associated Golgi protein
EAFBLIHF_01115 0.0 uvrA3 L excinuclease ABC, A subunit
EAFBLIHF_01116 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EAFBLIHF_01117 2.3e-60 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EAFBLIHF_01118 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EAFBLIHF_01119 7.6e-149 S DUF218 domain
EAFBLIHF_01120 0.0 ubiB S ABC1 family
EAFBLIHF_01121 2.2e-246 yhdP S Transporter associated domain
EAFBLIHF_01122 5e-75 copY K Copper transport repressor CopY TcrY
EAFBLIHF_01123 2.3e-246 EGP Major facilitator Superfamily
EAFBLIHF_01124 4.5e-74 yeaL S UPF0756 membrane protein
EAFBLIHF_01125 1.7e-62 yphH S Cupin domain
EAFBLIHF_01126 2.8e-87 C Flavodoxin
EAFBLIHF_01127 2.9e-162 K LysR substrate binding domain protein
EAFBLIHF_01128 6.2e-176 1.1.1.346 C Aldo keto reductase
EAFBLIHF_01129 2.1e-39 gcvR T Belongs to the UPF0237 family
EAFBLIHF_01130 1.6e-244 XK27_08635 S UPF0210 protein
EAFBLIHF_01131 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_01132 4.8e-96 K Acetyltransferase (GNAT) domain
EAFBLIHF_01133 1.2e-160 S Alpha beta hydrolase
EAFBLIHF_01134 3.1e-161 gspA M family 8
EAFBLIHF_01135 6e-120 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
EAFBLIHF_01136 9.4e-94
EAFBLIHF_01137 1.7e-162 degV S EDD domain protein, DegV family
EAFBLIHF_01138 0.0 FbpA K Fibronectin-binding protein
EAFBLIHF_01139 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
EAFBLIHF_01140 1.5e-208 carA 6.3.5.5 F Belongs to the CarA family
EAFBLIHF_01141 4.8e-176 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EAFBLIHF_01142 1.3e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EAFBLIHF_01143 1.5e-65 esbA S Family of unknown function (DUF5322)
EAFBLIHF_01144 6.9e-71 rnhA 3.1.26.4 L Ribonuclease HI
EAFBLIHF_01145 1.2e-232 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EAFBLIHF_01146 7.7e-85 F Belongs to the NrdI family
EAFBLIHF_01147 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EAFBLIHF_01148 1.6e-105 ypsA S Belongs to the UPF0398 family
EAFBLIHF_01149 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EAFBLIHF_01150 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
EAFBLIHF_01151 1.4e-162 EG EamA-like transporter family
EAFBLIHF_01152 5.1e-125 dnaD L DnaD domain protein
EAFBLIHF_01153 1.8e-87 ypmB S Protein conserved in bacteria
EAFBLIHF_01154 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EAFBLIHF_01155 2.1e-174 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EAFBLIHF_01156 4.6e-177 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EAFBLIHF_01157 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
EAFBLIHF_01158 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EAFBLIHF_01159 1.9e-89 S Protein of unknown function (DUF1440)
EAFBLIHF_01160 0.0 rafA 3.2.1.22 G alpha-galactosidase
EAFBLIHF_01161 6.3e-193 galR K Periplasmic binding protein-like domain
EAFBLIHF_01162 1.4e-80 scrK 2.7.1.2, 2.7.1.4 GK ROK family
EAFBLIHF_01163 2.5e-80 scrK 2.7.1.2, 2.7.1.4 GK ROK family
EAFBLIHF_01164 6.4e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EAFBLIHF_01165 2.6e-124 lrgB M LrgB-like family
EAFBLIHF_01166 1.9e-66 lrgA S LrgA family
EAFBLIHF_01167 1.1e-130 lytT K response regulator receiver
EAFBLIHF_01168 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
EAFBLIHF_01169 3.4e-147 f42a O Band 7 protein
EAFBLIHF_01170 2e-266 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EAFBLIHF_01171 2.9e-156 yitU 3.1.3.104 S hydrolase
EAFBLIHF_01172 3.2e-39 S Cytochrome B5
EAFBLIHF_01173 1.2e-117 nreC K PFAM regulatory protein LuxR
EAFBLIHF_01174 1.5e-161 hipB K Helix-turn-helix
EAFBLIHF_01175 2.8e-57 yitW S Iron-sulfur cluster assembly protein
EAFBLIHF_01176 4.2e-272 sufB O assembly protein SufB
EAFBLIHF_01177 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
EAFBLIHF_01178 1.6e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EAFBLIHF_01179 5.4e-242 sufD O FeS assembly protein SufD
EAFBLIHF_01180 6.5e-145 sufC O FeS assembly ATPase SufC
EAFBLIHF_01181 1.2e-31 feoA P FeoA domain
EAFBLIHF_01182 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EAFBLIHF_01183 1.6e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EAFBLIHF_01184 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EAFBLIHF_01185 1.6e-64 ydiI Q Thioesterase superfamily
EAFBLIHF_01186 2.4e-109 yvrI K sigma factor activity
EAFBLIHF_01187 5e-202 G Transporter, major facilitator family protein
EAFBLIHF_01188 0.0 S Bacterial membrane protein YfhO
EAFBLIHF_01189 3.9e-104 T Ion transport 2 domain protein
EAFBLIHF_01190 4.7e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EAFBLIHF_01191 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
EAFBLIHF_01192 4.5e-106 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
EAFBLIHF_01193 1.8e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAFBLIHF_01194 5.1e-181 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EAFBLIHF_01196 0.0 L PLD-like domain
EAFBLIHF_01197 4.3e-36 higA K addiction module antidote protein HigA
EAFBLIHF_01198 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
EAFBLIHF_01199 2.3e-180 3.1.21.3 V Type I restriction modification DNA specificity domain
EAFBLIHF_01200 1.5e-180 xerC L Belongs to the 'phage' integrase family
EAFBLIHF_01201 6.8e-113 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
EAFBLIHF_01202 9.5e-101 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
EAFBLIHF_01203 2.1e-301 2.1.1.72 V type I restriction-modification system
EAFBLIHF_01204 2.8e-58 yhaI S Protein of unknown function (DUF805)
EAFBLIHF_01205 2.2e-44
EAFBLIHF_01206 0.0 nylA 3.5.1.4 J Belongs to the amidase family
EAFBLIHF_01207 2.4e-22
EAFBLIHF_01208 1.7e-96 K Acetyltransferase (GNAT) domain
EAFBLIHF_01209 5.3e-297 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
EAFBLIHF_01210 1e-15 gntT EG Gluconate
EAFBLIHF_01211 8.8e-178 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EAFBLIHF_01212 2.9e-81 S Bacteriophage holin family
EAFBLIHF_01214 2e-76
EAFBLIHF_01217 2.8e-210
EAFBLIHF_01218 8.2e-32 S GDSL-like Lipase/Acylhydrolase
EAFBLIHF_01221 3.8e-11 GT2,GT4 LM gp58-like protein
EAFBLIHF_01222 0.0 S Peptidase family M23
EAFBLIHF_01223 3.9e-175 S Phage tail protein
EAFBLIHF_01224 0.0 D NLP P60 protein
EAFBLIHF_01225 9.4e-95 S Phage tail assembly chaperone protein, TAC
EAFBLIHF_01226 5.1e-124
EAFBLIHF_01227 1.1e-71
EAFBLIHF_01228 8.2e-86
EAFBLIHF_01229 3e-53
EAFBLIHF_01230 2.2e-63 S Phage gp6-like head-tail connector protein
EAFBLIHF_01231 8.9e-206 gpG
EAFBLIHF_01232 6.8e-108 S Domain of unknown function (DUF4355)
EAFBLIHF_01234 4.3e-180 S Phage Mu protein F like protein
EAFBLIHF_01235 0.0 S Phage portal protein, SPP1 Gp6-like
EAFBLIHF_01236 1.3e-264 S Phage terminase, large subunit
EAFBLIHF_01238 8e-140 K Belongs to the N(4) N(6)-methyltransferase family
EAFBLIHF_01239 5.7e-71
EAFBLIHF_01240 9.7e-126 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
EAFBLIHF_01242 8.9e-77
EAFBLIHF_01245 1.3e-07
EAFBLIHF_01254 3.8e-59
EAFBLIHF_01255 7e-153 L Psort location Cytoplasmic, score
EAFBLIHF_01256 4.9e-164 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
EAFBLIHF_01257 1.3e-165 recT L RecT family
EAFBLIHF_01262 6.5e-33
EAFBLIHF_01265 4.7e-140 K BRO family, N-terminal domain
EAFBLIHF_01266 3.4e-32 K Helix-turn-helix XRE-family like proteins
EAFBLIHF_01267 3.1e-56 3.4.21.88 K Helix-turn-helix domain
EAFBLIHF_01268 1.6e-70 S Pfam:DUF955
EAFBLIHF_01269 8e-75
EAFBLIHF_01271 2.6e-139
EAFBLIHF_01272 2.7e-238 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
EAFBLIHF_01273 9.1e-201 gntT EG Gluconate
EAFBLIHF_01274 1.4e-184 K Transcriptional regulator, LacI family
EAFBLIHF_01275 1.8e-292 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
EAFBLIHF_01276 2.9e-96
EAFBLIHF_01277 2.1e-25
EAFBLIHF_01278 1.1e-62 asp S Asp23 family, cell envelope-related function
EAFBLIHF_01279 4.4e-91 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
EAFBLIHF_01281 3.8e-32
EAFBLIHF_01282 8.3e-69 yqkB S Belongs to the HesB IscA family
EAFBLIHF_01283 1.2e-190 L PFAM Integrase catalytic region
EAFBLIHF_01284 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
EAFBLIHF_01285 8.9e-86 F NUDIX domain
EAFBLIHF_01286 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EAFBLIHF_01287 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EAFBLIHF_01288 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EAFBLIHF_01289 1.2e-171 lacX 5.1.3.3 G Aldose 1-epimerase
EAFBLIHF_01290 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EAFBLIHF_01291 3.1e-164 dprA LU DNA protecting protein DprA
EAFBLIHF_01292 1.2e-143 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EAFBLIHF_01293 6.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EAFBLIHF_01294 1.2e-35 yozE S Belongs to the UPF0346 family
EAFBLIHF_01295 7.4e-109 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
EAFBLIHF_01296 3.3e-172 ypmR E lipolytic protein G-D-S-L family
EAFBLIHF_01297 8.1e-154 DegV S EDD domain protein, DegV family
EAFBLIHF_01298 5.3e-113 hlyIII S protein, hemolysin III
EAFBLIHF_01299 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EAFBLIHF_01300 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EAFBLIHF_01301 0.0 yfmR S ABC transporter, ATP-binding protein
EAFBLIHF_01302 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EAFBLIHF_01303 3.9e-237 S Tetratricopeptide repeat protein
EAFBLIHF_01304 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EAFBLIHF_01305 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EAFBLIHF_01306 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
EAFBLIHF_01307 6.9e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EAFBLIHF_01308 2.5e-13 M Lysin motif
EAFBLIHF_01309 1e-273 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
EAFBLIHF_01310 8e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
EAFBLIHF_01311 5.3e-104 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EAFBLIHF_01312 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EAFBLIHF_01313 1.2e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EAFBLIHF_01314 1.9e-141 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EAFBLIHF_01315 1.1e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EAFBLIHF_01316 5.7e-166 xerD D recombinase XerD
EAFBLIHF_01317 1.6e-168 cvfB S S1 domain
EAFBLIHF_01318 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EAFBLIHF_01319 0.0 dnaE 2.7.7.7 L DNA polymerase
EAFBLIHF_01320 1.8e-30 S Protein of unknown function (DUF2929)
EAFBLIHF_01321 5.4e-239 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EAFBLIHF_01322 2.8e-159 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EAFBLIHF_01323 2.9e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
EAFBLIHF_01324 7.3e-261 S Uncharacterised protein family (UPF0236)
EAFBLIHF_01325 1.4e-220 patA 2.6.1.1 E Aminotransferase
EAFBLIHF_01326 7.7e-208 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EAFBLIHF_01327 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EAFBLIHF_01328 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EAFBLIHF_01329 7e-181 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EAFBLIHF_01330 2.3e-147 recO L Involved in DNA repair and RecF pathway recombination
EAFBLIHF_01331 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EAFBLIHF_01332 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EAFBLIHF_01333 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EAFBLIHF_01334 5.3e-184 phoH T phosphate starvation-inducible protein PhoH
EAFBLIHF_01335 2.4e-181 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EAFBLIHF_01336 4.6e-92 bioY S BioY family
EAFBLIHF_01337 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
EAFBLIHF_01338 9.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EAFBLIHF_01339 1.7e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EAFBLIHF_01340 2.9e-70 yqeY S YqeY-like protein
EAFBLIHF_01341 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EAFBLIHF_01342 2.8e-266 glnPH2 P ABC transporter permease
EAFBLIHF_01343 8.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EAFBLIHF_01344 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_01345 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EAFBLIHF_01346 2.8e-170 yniA G Phosphotransferase enzyme family
EAFBLIHF_01347 1.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EAFBLIHF_01348 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAFBLIHF_01349 9.3e-53
EAFBLIHF_01350 1.3e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EAFBLIHF_01351 1.6e-182 prmA J Ribosomal protein L11 methyltransferase
EAFBLIHF_01352 7.5e-58
EAFBLIHF_01354 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EAFBLIHF_01355 1.7e-201 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
EAFBLIHF_01356 7.9e-279 pipD E Dipeptidase
EAFBLIHF_01357 9.2e-24 3.4.21.88 K Peptidase S24-like
EAFBLIHF_01358 1.4e-10 3.4.21.88 K Peptidase S24-like
EAFBLIHF_01359 1e-81
EAFBLIHF_01360 4.7e-76
EAFBLIHF_01361 6.4e-13
EAFBLIHF_01362 8.1e-142
EAFBLIHF_01363 5.4e-225 3.6.4.12 L Belongs to the 'phage' integrase family
EAFBLIHF_01364 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EAFBLIHF_01365 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EAFBLIHF_01366 0.0 dnaK O Heat shock 70 kDa protein
EAFBLIHF_01367 1.2e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EAFBLIHF_01368 1.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EAFBLIHF_01369 2e-64
EAFBLIHF_01370 1.9e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EAFBLIHF_01371 1.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EAFBLIHF_01372 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EAFBLIHF_01373 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EAFBLIHF_01374 4.5e-49 ylxQ J ribosomal protein
EAFBLIHF_01375 1e-44 ylxR K Protein of unknown function (DUF448)
EAFBLIHF_01376 1.2e-216 nusA K Participates in both transcription termination and antitermination
EAFBLIHF_01377 1.4e-83 rimP J Required for maturation of 30S ribosomal subunits
EAFBLIHF_01378 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EAFBLIHF_01379 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EAFBLIHF_01380 9.8e-236 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EAFBLIHF_01381 3.4e-138 cdsA 2.7.7.41 I Belongs to the CDS family
EAFBLIHF_01382 4.5e-143 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EAFBLIHF_01383 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_01384 1.1e-222 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_01385 7.4e-95 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EAFBLIHF_01386 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EAFBLIHF_01387 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EAFBLIHF_01388 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
EAFBLIHF_01389 5.2e-184 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAFBLIHF_01390 5.4e-49 yazA L GIY-YIG catalytic domain protein
EAFBLIHF_01391 3.7e-142 yabB 2.1.1.223 L Methyltransferase small domain
EAFBLIHF_01392 1.6e-117 plsC 2.3.1.51 I Acyltransferase
EAFBLIHF_01393 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
EAFBLIHF_01394 1.3e-35 ynzC S UPF0291 protein
EAFBLIHF_01395 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EAFBLIHF_01396 1.5e-214 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
EAFBLIHF_01397 8.4e-130 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EAFBLIHF_01399 1.6e-45 S Phage gp6-like head-tail connector protein
EAFBLIHF_01400 1.5e-76 S Transcriptional regulator, RinA family
EAFBLIHF_01401 2.3e-284 S Caudovirus prohead serine protease
EAFBLIHF_01402 3.4e-208 S Phage portal protein
EAFBLIHF_01404 0.0 terL S overlaps another CDS with the same product name
EAFBLIHF_01405 2.1e-79 terS L Phage terminase, small subunit
EAFBLIHF_01407 1.2e-85 L HNH nucleases
EAFBLIHF_01409 5e-12 S head-tail joining protein
EAFBLIHF_01410 1.2e-274 S Phage plasmid primase, P4
EAFBLIHF_01414 1.3e-81 recJ L Single-stranded-DNA-specific exonuclease RecJ
EAFBLIHF_01415 2e-157 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EAFBLIHF_01416 9.8e-177 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EAFBLIHF_01417 1.2e-249 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EAFBLIHF_01418 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EAFBLIHF_01419 7.6e-09
EAFBLIHF_01420 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
EAFBLIHF_01421 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
EAFBLIHF_01422 6.2e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EAFBLIHF_01423 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EAFBLIHF_01424 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EAFBLIHF_01425 4.9e-165 S Tetratricopeptide repeat
EAFBLIHF_01426 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EAFBLIHF_01427 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EAFBLIHF_01428 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
EAFBLIHF_01429 2.5e-149 holA 2.7.7.7 L DNA polymerase III delta subunit
EAFBLIHF_01430 0.0 comEC S Competence protein ComEC
EAFBLIHF_01431 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
EAFBLIHF_01432 8.1e-82 comEA L Competence protein ComEA
EAFBLIHF_01433 7.1e-200 ylbL T Belongs to the peptidase S16 family
EAFBLIHF_01434 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EAFBLIHF_01435 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
EAFBLIHF_01436 1e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
EAFBLIHF_01437 8.2e-224 ftsW D Belongs to the SEDS family
EAFBLIHF_01438 0.0 typA T GTP-binding protein TypA
EAFBLIHF_01439 5.7e-138 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EAFBLIHF_01440 6.1e-48 yktA S Belongs to the UPF0223 family
EAFBLIHF_01441 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
EAFBLIHF_01442 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EAFBLIHF_01443 6.2e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
EAFBLIHF_01444 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EAFBLIHF_01445 5.6e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EAFBLIHF_01446 3.6e-82
EAFBLIHF_01447 9.8e-32 ykzG S Belongs to the UPF0356 family
EAFBLIHF_01448 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
EAFBLIHF_01449 5.7e-29
EAFBLIHF_01450 3.7e-143 mltD CBM50 M NlpC P60 family protein
EAFBLIHF_01452 7.7e-58
EAFBLIHF_01453 1.5e-211 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EAFBLIHF_01454 5.9e-220 EG GntP family permease
EAFBLIHF_01455 2.9e-27 KT Putative sugar diacid recognition
EAFBLIHF_01456 1.4e-32 KT Putative sugar diacid recognition
EAFBLIHF_01457 6.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAFBLIHF_01458 2.6e-222 patA 2.6.1.1 E Aminotransferase
EAFBLIHF_01459 2.3e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EAFBLIHF_01460 1.6e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAFBLIHF_01461 7e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EAFBLIHF_01462 2.1e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EAFBLIHF_01463 1e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EAFBLIHF_01464 7.2e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
EAFBLIHF_01465 2.7e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EAFBLIHF_01466 2.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAFBLIHF_01467 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EAFBLIHF_01468 3.4e-118 S Repeat protein
EAFBLIHF_01469 3.4e-123 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
EAFBLIHF_01470 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EAFBLIHF_01471 7.5e-58 XK27_04120 S Putative amino acid metabolism
EAFBLIHF_01472 2.9e-218 iscS 2.8.1.7 E Aminotransferase class V
EAFBLIHF_01473 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAFBLIHF_01475 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
EAFBLIHF_01476 4.2e-32 cspA K Cold shock protein
EAFBLIHF_01477 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EAFBLIHF_01478 6.4e-38 divIVA D DivIVA domain protein
EAFBLIHF_01479 1.3e-145 ylmH S S4 domain protein
EAFBLIHF_01480 8.3e-41 yggT S YGGT family
EAFBLIHF_01481 1.2e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EAFBLIHF_01482 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EAFBLIHF_01483 2.9e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EAFBLIHF_01484 3.2e-150 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EAFBLIHF_01485 9.2e-206 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EAFBLIHF_01486 2.7e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EAFBLIHF_01487 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EAFBLIHF_01488 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
EAFBLIHF_01489 1.5e-56 ftsL D Cell division protein FtsL
EAFBLIHF_01490 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EAFBLIHF_01491 3.1e-77 mraZ K Belongs to the MraZ family
EAFBLIHF_01492 7.8e-58
EAFBLIHF_01493 1.2e-10 S Protein of unknown function (DUF4044)
EAFBLIHF_01494 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EAFBLIHF_01495 4.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EAFBLIHF_01496 4.4e-163 rrmA 2.1.1.187 H Methyltransferase
EAFBLIHF_01497 7e-184 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
EAFBLIHF_01499 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
EAFBLIHF_01500 4e-96 L Transposase IS66 family
EAFBLIHF_01501 2.2e-187 L Transposase IS66 family
EAFBLIHF_01505 1.6e-66 XK27_01125 L PFAM IS66 Orf2 family protein
EAFBLIHF_01506 3.2e-297 L Transposase IS66 family
EAFBLIHF_01508 2.8e-19
EAFBLIHF_01509 1.3e-263 dtpT U amino acid peptide transporter
EAFBLIHF_01510 5.2e-161 yjjH S Calcineurin-like phosphoesterase
EAFBLIHF_01513 1.5e-115
EAFBLIHF_01514 9.7e-253 EGP Major facilitator Superfamily
EAFBLIHF_01515 2.9e-304 aspT P Predicted Permease Membrane Region
EAFBLIHF_01516 2.5e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EAFBLIHF_01517 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
EAFBLIHF_01518 1.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EAFBLIHF_01519 3.9e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EAFBLIHF_01520 0.0 yhgF K Tex-like protein N-terminal domain protein
EAFBLIHF_01521 8.6e-86 ydcK S Belongs to the SprT family
EAFBLIHF_01523 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
EAFBLIHF_01524 7.5e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
EAFBLIHF_01525 0.0 S Bacterial membrane protein, YfhO
EAFBLIHF_01526 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EAFBLIHF_01527 6.3e-170 I alpha/beta hydrolase fold
EAFBLIHF_01528 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EAFBLIHF_01529 1.1e-119 tcyB E ABC transporter
EAFBLIHF_01530 2.6e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EAFBLIHF_01531 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EAFBLIHF_01532 5.4e-269 pepC 3.4.22.40 E Peptidase C1-like family
EAFBLIHF_01533 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EAFBLIHF_01534 8.5e-50 HA62_12640 S GCN5-related N-acetyl-transferase
EAFBLIHF_01535 2.3e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
EAFBLIHF_01536 3.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EAFBLIHF_01537 1e-207 yacL S domain protein
EAFBLIHF_01538 2.6e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EAFBLIHF_01539 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EAFBLIHF_01540 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAFBLIHF_01541 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EAFBLIHF_01542 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EAFBLIHF_01543 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
EAFBLIHF_01544 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EAFBLIHF_01545 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EAFBLIHF_01546 7e-228 aadAT EK Aminotransferase, class I
EAFBLIHF_01548 2.1e-249 M Glycosyl transferase family group 2
EAFBLIHF_01549 2.7e-213 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EAFBLIHF_01550 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EAFBLIHF_01551 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EAFBLIHF_01552 3.4e-48
EAFBLIHF_01554 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EAFBLIHF_01555 1.1e-56 K transcriptional regulator PadR family
EAFBLIHF_01556 6.2e-79 XK27_06920 S Protein of unknown function (DUF1700)
EAFBLIHF_01557 1.1e-136 S Putative adhesin
EAFBLIHF_01558 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EAFBLIHF_01559 1.2e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAFBLIHF_01560 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAFBLIHF_01561 3.4e-35 nrdH O Glutaredoxin
EAFBLIHF_01562 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EAFBLIHF_01563 7.3e-309 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EAFBLIHF_01564 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EAFBLIHF_01565 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EAFBLIHF_01566 9.7e-39 S Protein of unknown function (DUF2508)
EAFBLIHF_01567 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EAFBLIHF_01568 7.6e-52 yaaQ S Cyclic-di-AMP receptor
EAFBLIHF_01569 1.5e-186 holB 2.7.7.7 L DNA polymerase III
EAFBLIHF_01570 1.6e-58 yabA L Involved in initiation control of chromosome replication
EAFBLIHF_01571 1.5e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EAFBLIHF_01572 1.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
EAFBLIHF_01573 2.7e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EAFBLIHF_01574 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EAFBLIHF_01575 6.6e-176 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EAFBLIHF_01576 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EAFBLIHF_01577 1.2e-213 L PFAM Integrase catalytic region
EAFBLIHF_01578 1.5e-32 L PFAM Integrase catalytic region
EAFBLIHF_01579 6.3e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
EAFBLIHF_01580 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
EAFBLIHF_01581 1.9e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EAFBLIHF_01582 2.9e-134 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EAFBLIHF_01583 3.5e-230 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EAFBLIHF_01584 1.4e-139 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EAFBLIHF_01585 3.6e-148 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
EAFBLIHF_01586 4.3e-230 mtnE 2.6.1.83 E Aminotransferase
EAFBLIHF_01587 1.9e-186 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAFBLIHF_01588 2.2e-311 L Transposase
EAFBLIHF_01589 0.0 uup S ABC transporter, ATP-binding protein
EAFBLIHF_01590 6.3e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EAFBLIHF_01592 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EAFBLIHF_01593 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EAFBLIHF_01594 4.2e-86 S Aminoacyl-tRNA editing domain
EAFBLIHF_01595 4.3e-305 ybeC E amino acid
EAFBLIHF_01596 0.0 ydaO E amino acid
EAFBLIHF_01597 9.2e-40
EAFBLIHF_01598 3.3e-68 rmaI K Transcriptional regulator
EAFBLIHF_01599 1.3e-249 EGP Major facilitator Superfamily
EAFBLIHF_01600 2e-112 yvyE 3.4.13.9 S YigZ family
EAFBLIHF_01601 2.3e-259 comFA L Helicase C-terminal domain protein
EAFBLIHF_01602 2.6e-126 comFC S Competence protein
EAFBLIHF_01603 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAFBLIHF_01604 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EAFBLIHF_01605 9.2e-189 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EAFBLIHF_01606 2.4e-32 KT PspC domain protein
EAFBLIHF_01607 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
EAFBLIHF_01608 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EAFBLIHF_01609 1.3e-159 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EAFBLIHF_01610 2.4e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EAFBLIHF_01611 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EAFBLIHF_01612 2.4e-138 yrjD S LUD domain
EAFBLIHF_01613 4.4e-296 lutB C 4Fe-4S dicluster domain
EAFBLIHF_01614 1.9e-169 lutA C Cysteine-rich domain
EAFBLIHF_01615 4.6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EAFBLIHF_01616 1.3e-221 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
EAFBLIHF_01617 1.6e-165 aatB ET PFAM extracellular solute-binding protein, family 3
EAFBLIHF_01618 9.1e-84 ykhA 3.1.2.20 I Thioesterase superfamily
EAFBLIHF_01619 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EAFBLIHF_01620 2.3e-116 yfbR S HD containing hydrolase-like enzyme
EAFBLIHF_01621 1.5e-13
EAFBLIHF_01622 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EAFBLIHF_01623 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EAFBLIHF_01624 2.4e-245 steT E amino acid
EAFBLIHF_01625 1.7e-162 rapZ S Displays ATPase and GTPase activities
EAFBLIHF_01626 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EAFBLIHF_01627 2.4e-170 whiA K May be required for sporulation
EAFBLIHF_01629 8.8e-15
EAFBLIHF_01630 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EAFBLIHF_01631 1.5e-256 L Transposase
EAFBLIHF_01632 3.5e-16 L Transposase
EAFBLIHF_01634 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EAFBLIHF_01635 7.1e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EAFBLIHF_01636 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EAFBLIHF_01637 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EAFBLIHF_01638 2.2e-311 L Transposase
EAFBLIHF_01639 1.9e-245 yifK E Amino acid permease
EAFBLIHF_01640 5.6e-294 clcA P chloride
EAFBLIHF_01641 1.8e-34 secG U Preprotein translocase
EAFBLIHF_01642 2.1e-148 est 3.1.1.1 S Serine aminopeptidase, S33
EAFBLIHF_01643 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EAFBLIHF_01644 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EAFBLIHF_01645 6.3e-105 yxjI
EAFBLIHF_01646 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EAFBLIHF_01647 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EAFBLIHF_01648 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
EAFBLIHF_01649 6.1e-88 K Acetyltransferase (GNAT) domain
EAFBLIHF_01650 8.9e-77 S PAS domain
EAFBLIHF_01651 9.3e-103 dnaQ 2.7.7.7 L DNA polymerase III
EAFBLIHF_01652 7.3e-169 murB 1.3.1.98 M Cell wall formation
EAFBLIHF_01653 1.2e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAFBLIHF_01654 6e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EAFBLIHF_01655 3.7e-249 fucP G Major Facilitator Superfamily
EAFBLIHF_01656 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EAFBLIHF_01657 1.2e-126 ybbR S YbbR-like protein
EAFBLIHF_01658 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAFBLIHF_01659 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EAFBLIHF_01660 8.7e-53
EAFBLIHF_01661 0.0 oatA I Acyltransferase
EAFBLIHF_01662 2.1e-79 K Transcriptional regulator
EAFBLIHF_01663 8.9e-150 XK27_02985 S Cof-like hydrolase
EAFBLIHF_01664 1.8e-78 lytE M Lysin motif
EAFBLIHF_01666 3.8e-136 K response regulator
EAFBLIHF_01667 8.1e-274 yclK 2.7.13.3 T Histidine kinase
EAFBLIHF_01668 5.7e-155 glcU U sugar transport
EAFBLIHF_01669 1.4e-102 lacA 2.3.1.79 S Transferase hexapeptide repeat
EAFBLIHF_01670 5.3e-264 pgi 5.3.1.9 G Belongs to the GPI family
EAFBLIHF_01671 2.1e-26
EAFBLIHF_01673 5.6e-32 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
EAFBLIHF_01674 9.7e-85 L PFAM transposase IS200-family protein
EAFBLIHF_01675 2.5e-155 KT YcbB domain
EAFBLIHF_01676 2.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EAFBLIHF_01677 1.5e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
EAFBLIHF_01678 3.2e-164 EG EamA-like transporter family
EAFBLIHF_01679 2e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
EAFBLIHF_01680 7.6e-48 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EAFBLIHF_01681 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
EAFBLIHF_01682 0.0 copA 3.6.3.54 P P-type ATPase
EAFBLIHF_01683 1.6e-90
EAFBLIHF_01685 3.6e-57
EAFBLIHF_01686 1.1e-240 yjcE P Sodium proton antiporter
EAFBLIHF_01690 1.7e-237 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EAFBLIHF_01691 2.1e-66
EAFBLIHF_01693 4.8e-72
EAFBLIHF_01695 5.3e-08 L DnaD domain protein
EAFBLIHF_01698 1.6e-140 L hmm pf00665
EAFBLIHF_01699 5.8e-106 L Helix-turn-helix domain
EAFBLIHF_01700 4.5e-26
EAFBLIHF_01701 1.1e-197 ampC V Beta-lactamase
EAFBLIHF_01702 4.1e-239 arcA 3.5.3.6 E Arginine
EAFBLIHF_01703 1.2e-79 argR K Regulates arginine biosynthesis genes
EAFBLIHF_01704 6.8e-262 E Arginine ornithine antiporter
EAFBLIHF_01705 1.6e-226 arcD U Amino acid permease
EAFBLIHF_01706 1.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
EAFBLIHF_01707 8.9e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
EAFBLIHF_01708 6e-108 tdk 2.7.1.21 F thymidine kinase
EAFBLIHF_01709 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EAFBLIHF_01710 1.4e-169 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EAFBLIHF_01711 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EAFBLIHF_01712 9.8e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EAFBLIHF_01713 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EAFBLIHF_01714 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAFBLIHF_01715 3.3e-195 yibE S overlaps another CDS with the same product name
EAFBLIHF_01716 1.8e-131 yibF S overlaps another CDS with the same product name
EAFBLIHF_01717 5.9e-233 pyrP F Permease
EAFBLIHF_01718 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
EAFBLIHF_01719 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EAFBLIHF_01720 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EAFBLIHF_01721 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EAFBLIHF_01722 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EAFBLIHF_01723 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EAFBLIHF_01724 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EAFBLIHF_01725 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EAFBLIHF_01726 1.3e-33 ywzB S Protein of unknown function (DUF1146)
EAFBLIHF_01727 6.5e-243 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EAFBLIHF_01728 1.9e-178 mbl D Cell shape determining protein MreB Mrl
EAFBLIHF_01729 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EAFBLIHF_01730 2.7e-32 S Protein of unknown function (DUF2969)
EAFBLIHF_01731 1.1e-220 rodA D Belongs to the SEDS family
EAFBLIHF_01732 1e-47 gcvH E glycine cleavage
EAFBLIHF_01733 7.3e-261 S Uncharacterised protein family (UPF0236)
EAFBLIHF_01734 6.3e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EAFBLIHF_01735 2.7e-62 2.3.1.19 K Helix-turn-helix XRE-family like proteins
EAFBLIHF_01736 2.8e-67 2.3.1.19 K Helix-turn-helix XRE-family like proteins
EAFBLIHF_01737 5.2e-262 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EAFBLIHF_01738 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
EAFBLIHF_01739 3.7e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
EAFBLIHF_01740 8.8e-286 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EAFBLIHF_01741 2e-100 maa 2.3.1.79 S Maltose O-acetyltransferase
EAFBLIHF_01742 2.2e-159 ytbE 1.1.1.346 S Aldo keto reductase
EAFBLIHF_01743 1.5e-208 araR K Transcriptional regulator
EAFBLIHF_01744 4.3e-83 usp6 T universal stress protein
EAFBLIHF_01745 4.4e-46
EAFBLIHF_01746 3.4e-244 rarA L recombination factor protein RarA
EAFBLIHF_01747 1.7e-87 yueI S Protein of unknown function (DUF1694)
EAFBLIHF_01748 1e-20
EAFBLIHF_01749 1.6e-75 4.4.1.5 E Glyoxalase
EAFBLIHF_01750 2.5e-138 S Membrane
EAFBLIHF_01751 1.1e-141 S Belongs to the UPF0246 family
EAFBLIHF_01752 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
EAFBLIHF_01753 6.7e-164 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
EAFBLIHF_01754 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_01755 7.3e-85 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
EAFBLIHF_01756 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_01757 1.1e-235 pbuG S permease
EAFBLIHF_01758 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EAFBLIHF_01759 9e-253 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EAFBLIHF_01760 7e-217 iscS2 2.8.1.7 E Aminotransferase class V
EAFBLIHF_01761 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAFBLIHF_01762 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EAFBLIHF_01763 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
EAFBLIHF_01764 3.3e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
EAFBLIHF_01765 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EAFBLIHF_01766 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EAFBLIHF_01767 4.8e-232 ndh 1.6.99.3 C NADH dehydrogenase
EAFBLIHF_01768 9.4e-250 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EAFBLIHF_01769 1.2e-122 radC L DNA repair protein
EAFBLIHF_01770 1.7e-179 mreB D cell shape determining protein MreB
EAFBLIHF_01771 5.9e-152 mreC M Involved in formation and maintenance of cell shape
EAFBLIHF_01772 8.7e-93 mreD M rod shape-determining protein MreD
EAFBLIHF_01773 3.2e-102 glnP P ABC transporter permease
EAFBLIHF_01774 1.2e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
EAFBLIHF_01775 1.5e-160 aatB ET ABC transporter substrate-binding protein
EAFBLIHF_01776 4.2e-231 ymfF S Peptidase M16 inactive domain protein
EAFBLIHF_01777 2.4e-250 ymfH S Peptidase M16
EAFBLIHF_01778 1.9e-141 ymfM S Helix-turn-helix domain
EAFBLIHF_01779 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EAFBLIHF_01780 3.4e-233 cinA 3.5.1.42 S Belongs to the CinA family
EAFBLIHF_01781 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EAFBLIHF_01782 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
EAFBLIHF_01783 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EAFBLIHF_01784 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EAFBLIHF_01785 1.8e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EAFBLIHF_01786 1.2e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EAFBLIHF_01787 2.2e-204 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EAFBLIHF_01788 1.5e-29 yajC U Preprotein translocase
EAFBLIHF_01789 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
EAFBLIHF_01790 1.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EAFBLIHF_01791 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EAFBLIHF_01792 4.1e-43 yrzL S Belongs to the UPF0297 family
EAFBLIHF_01793 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EAFBLIHF_01794 6.1e-48 yrzB S Belongs to the UPF0473 family
EAFBLIHF_01795 1.6e-86 cvpA S Colicin V production protein
EAFBLIHF_01796 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EAFBLIHF_01797 6.1e-54 trxA O Belongs to the thioredoxin family
EAFBLIHF_01798 4.1e-98 yslB S Protein of unknown function (DUF2507)
EAFBLIHF_01799 1.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EAFBLIHF_01800 1.8e-107 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EAFBLIHF_01801 2.1e-96 S Phosphoesterase
EAFBLIHF_01802 2.7e-76 ykuL S (CBS) domain
EAFBLIHF_01803 1.2e-154 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
EAFBLIHF_01804 2.1e-149 ykuT M mechanosensitive ion channel
EAFBLIHF_01805 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EAFBLIHF_01806 1.8e-14
EAFBLIHF_01807 1.2e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
EAFBLIHF_01808 4.5e-183 ccpA K catabolite control protein A
EAFBLIHF_01809 1.8e-137
EAFBLIHF_01810 3.5e-132 yebC K Transcriptional regulatory protein
EAFBLIHF_01811 7.9e-185 comGA NU Type II IV secretion system protein
EAFBLIHF_01812 2.3e-187 comGB NU type II secretion system
EAFBLIHF_01813 7.1e-47 comGC U competence protein ComGC
EAFBLIHF_01814 1.5e-79 NU general secretion pathway protein
EAFBLIHF_01815 4.8e-45
EAFBLIHF_01816 3.6e-73
EAFBLIHF_01818 5.9e-146 ytxK 2.1.1.72 L N-6 DNA Methylase
EAFBLIHF_01819 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EAFBLIHF_01820 8.8e-118 S Calcineurin-like phosphoesterase
EAFBLIHF_01821 4.4e-100 yutD S Protein of unknown function (DUF1027)
EAFBLIHF_01822 2.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EAFBLIHF_01823 2.8e-114 S Protein of unknown function (DUF1461)
EAFBLIHF_01824 5.5e-110 dedA S SNARE-like domain protein
EAFBLIHF_01846 5.2e-167 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EAFBLIHF_01849 2.3e-65 XK27_01125 L PFAM IS66 Orf2 family protein
EAFBLIHF_01850 1.8e-289 L Transposase IS66 family
EAFBLIHF_01852 4.9e-87
EAFBLIHF_01853 4.7e-190 L PFAM Integrase catalytic region
EAFBLIHF_01854 1.9e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
EAFBLIHF_01855 2.7e-274 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EAFBLIHF_01856 1e-104 pncA Q Isochorismatase family
EAFBLIHF_01857 1.1e-208 yegU O ADP-ribosylglycohydrolase
EAFBLIHF_01858 1.8e-256 F Belongs to the purine-cytosine permease (2.A.39) family
EAFBLIHF_01859 7.9e-168 G Belongs to the carbohydrate kinase PfkB family
EAFBLIHF_01860 5.6e-39 hxlR K regulation of RNA biosynthetic process
EAFBLIHF_01861 3.3e-242 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
EAFBLIHF_01862 2.6e-132 IQ Dehydrogenase reductase
EAFBLIHF_01863 4.4e-38
EAFBLIHF_01864 5.7e-115 ywnB S NAD(P)H-binding
EAFBLIHF_01865 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
EAFBLIHF_01866 2.3e-257 nhaC C Na H antiporter NhaC
EAFBLIHF_01867 1.7e-108 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EAFBLIHF_01868 1.9e-50 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EAFBLIHF_01870 5.5e-103 ydeN S Serine hydrolase
EAFBLIHF_01871 2e-62 psiE S Phosphate-starvation-inducible E
EAFBLIHF_01872 2.9e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EAFBLIHF_01874 2.1e-182 S Aldo keto reductase
EAFBLIHF_01875 1.5e-67 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
EAFBLIHF_01876 0.0 L Helicase C-terminal domain protein
EAFBLIHF_01878 1.8e-256 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
EAFBLIHF_01879 3.3e-55 S Sugar efflux transporter for intercellular exchange
EAFBLIHF_01880 4.4e-129
EAFBLIHF_01881 6.4e-131 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
EAFBLIHF_01882 0.0 cadA P P-type ATPase
EAFBLIHF_01883 3.1e-228 5.4.2.7 G Metalloenzyme superfamily
EAFBLIHF_01885 3.8e-159 1.6.5.2 GM NAD(P)H-binding
EAFBLIHF_01886 5.8e-52 K Transcriptional regulator
EAFBLIHF_01887 7e-164 proX M ABC transporter, substrate-binding protein, QAT family
EAFBLIHF_01888 9.7e-110 proWZ P ABC transporter permease
EAFBLIHF_01889 1.3e-142 proV E ABC transporter, ATP-binding protein
EAFBLIHF_01890 5.8e-104 proW P ABC transporter, permease protein
EAFBLIHF_01891 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EAFBLIHF_01892 4.9e-254 clcA P chloride
EAFBLIHF_01893 4.4e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
EAFBLIHF_01894 3.1e-103 metI P ABC transporter permease
EAFBLIHF_01895 1.5e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAFBLIHF_01896 3.9e-156 metQ1 P Belongs to the nlpA lipoprotein family
EAFBLIHF_01897 3.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EAFBLIHF_01898 1.7e-221 norA EGP Major facilitator Superfamily
EAFBLIHF_01899 8.6e-44 1.3.5.4 S FMN binding
EAFBLIHF_01900 4.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EAFBLIHF_01901 1.2e-266 yfnA E amino acid
EAFBLIHF_01902 6.3e-257 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EAFBLIHF_01904 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EAFBLIHF_01905 0.0 helD 3.6.4.12 L DNA helicase
EAFBLIHF_01906 1.7e-81 ndk 2.7.4.6 F Belongs to the NDK family
EAFBLIHF_01907 1.3e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
EAFBLIHF_01908 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
EAFBLIHF_01909 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
EAFBLIHF_01910 1.3e-232 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EAFBLIHF_01911 1.1e-178
EAFBLIHF_01912 4.2e-132 cobB K SIR2 family
EAFBLIHF_01914 7.4e-163 yunF F Protein of unknown function DUF72
EAFBLIHF_01915 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAFBLIHF_01916 1.5e-157 tatD L hydrolase, TatD family
EAFBLIHF_01917 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EAFBLIHF_01918 3.8e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EAFBLIHF_01919 6.8e-37 veg S Biofilm formation stimulator VEG
EAFBLIHF_01920 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EAFBLIHF_01921 1.3e-170 znuA P Belongs to the bacterial solute-binding protein 9 family
EAFBLIHF_01922 7.7e-123 fhuC P ABC transporter
EAFBLIHF_01923 3.2e-128 znuB U ABC 3 transport family
EAFBLIHF_01924 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
EAFBLIHF_01925 1.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EAFBLIHF_01926 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAFBLIHF_01927 5.6e-50
EAFBLIHF_01928 4.1e-150 yxeH S hydrolase
EAFBLIHF_01929 2.4e-272 ywfO S HD domain protein
EAFBLIHF_01930 1.7e-156 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
EAFBLIHF_01931 1.9e-61 L PFAM transposase IS200-family protein
EAFBLIHF_01932 8.7e-231 L transposase, IS605 OrfB family
EAFBLIHF_01933 2.1e-67 ywiB S Domain of unknown function (DUF1934)
EAFBLIHF_01934 1.5e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EAFBLIHF_01935 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EAFBLIHF_01936 3e-262 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_01937 8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EAFBLIHF_01938 4.6e-41 rpmE2 J Ribosomal protein L31
EAFBLIHF_01939 6.1e-241 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EAFBLIHF_01940 2.7e-168 S Alpha/beta hydrolase of unknown function (DUF915)
EAFBLIHF_01941 5.1e-125 srtA 3.4.22.70 M sortase family
EAFBLIHF_01942 1e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EAFBLIHF_01943 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
EAFBLIHF_01944 9.2e-121 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
EAFBLIHF_01945 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EAFBLIHF_01946 7e-93 lemA S LemA family
EAFBLIHF_01947 8.9e-159 htpX O Belongs to the peptidase M48B family
EAFBLIHF_01948 5.2e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EAFBLIHF_01949 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EAFBLIHF_01950 1.4e-153 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EAFBLIHF_01951 2.4e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
EAFBLIHF_01952 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_01953 5.4e-264 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_01954 5.6e-255 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EAFBLIHF_01955 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EAFBLIHF_01956 2.7e-235 dltB M MBOAT, membrane-bound O-acyltransferase family
EAFBLIHF_01957 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EAFBLIHF_01959 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EAFBLIHF_01960 7.9e-213 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAFBLIHF_01961 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
EAFBLIHF_01962 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
EAFBLIHF_01963 2.1e-243 codA 3.5.4.1 F cytosine deaminase
EAFBLIHF_01964 3.1e-147 tesE Q hydratase
EAFBLIHF_01965 3.6e-114 S (CBS) domain
EAFBLIHF_01966 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EAFBLIHF_01967 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EAFBLIHF_01968 1.6e-39 yabO J S4 domain protein
EAFBLIHF_01969 2.3e-57 divIC D Septum formation initiator
EAFBLIHF_01970 9.8e-67 yabR J RNA binding
EAFBLIHF_01971 4.3e-269 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EAFBLIHF_01972 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EAFBLIHF_01973 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAFBLIHF_01974 3.6e-171 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EAFBLIHF_01975 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAFBLIHF_01976 4.2e-294 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EAFBLIHF_01977 1.7e-88
EAFBLIHF_01981 3e-65 XK27_01125 L PFAM IS66 Orf2 family protein
EAFBLIHF_01983 2.8e-210
EAFBLIHF_01986 1.5e-76
EAFBLIHF_01988 4.5e-36
EAFBLIHF_01989 1.1e-59 hol S COG5546 Small integral membrane protein
EAFBLIHF_01990 7.4e-177 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EAFBLIHF_01991 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_01992 7.7e-35
EAFBLIHF_01993 4.4e-55 S Mazg nucleotide pyrophosphohydrolase
EAFBLIHF_01994 8.8e-161 xth 3.1.11.2 L exodeoxyribonuclease III
EAFBLIHF_01995 3.5e-263 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EAFBLIHF_01996 5e-84
EAFBLIHF_01997 2.2e-190 lacR K Transcriptional regulator
EAFBLIHF_01998 0.0 lacS G Transporter
EAFBLIHF_01999 0.0 lacZ 3.2.1.23 G -beta-galactosidase
EAFBLIHF_02000 1.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EAFBLIHF_02001 6.8e-159 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
EAFBLIHF_02002 1.3e-144 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
EAFBLIHF_02003 7.7e-224 yxjG_1 E methionine synthase, vitamin-B12 independent
EAFBLIHF_02004 2.8e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EAFBLIHF_02005 8.2e-224 mdtG EGP Major facilitator Superfamily
EAFBLIHF_02006 1.2e-168 T Calcineurin-like phosphoesterase superfamily domain
EAFBLIHF_02007 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EAFBLIHF_02010 1.2e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
EAFBLIHF_02011 3e-143 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
EAFBLIHF_02012 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
EAFBLIHF_02013 0.0 trxB2 1.8.1.9 C Thioredoxin domain
EAFBLIHF_02014 1.5e-163 L hmm pf00665
EAFBLIHF_02015 2.5e-127 L Helix-turn-helix domain
EAFBLIHF_02016 6.7e-278 pipD E Dipeptidase
EAFBLIHF_02017 0.0 yjbQ P TrkA C-terminal domain protein
EAFBLIHF_02018 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EAFBLIHF_02019 5.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EAFBLIHF_02020 4e-92
EAFBLIHF_02021 1.7e-37
EAFBLIHF_02022 1.2e-105 K DNA-templated transcription, initiation
EAFBLIHF_02023 4e-28
EAFBLIHF_02024 1.2e-60 L PFAM transposase IS200-family protein
EAFBLIHF_02025 3.3e-230 L transposase, IS605 OrfB family
EAFBLIHF_02026 2e-94
EAFBLIHF_02027 2.2e-69 K Transcriptional regulator, HxlR family
EAFBLIHF_02028 2.3e-171 brpA K Cell envelope-like function transcriptional attenuator common domain protein
EAFBLIHF_02029 6e-22 epsB M biosynthesis protein
EAFBLIHF_02030 7.9e-168 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EAFBLIHF_02031 1.8e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EAFBLIHF_02032 2.8e-264 S Protein of unknown function (DUF2971)
EAFBLIHF_02033 0.0 S KAP family P-loop domain
EAFBLIHF_02034 2.3e-306 S AAA domain, putative AbiEii toxin, Type IV TA system
EAFBLIHF_02035 4.8e-207 3.6.4.12 L DNA helicase
EAFBLIHF_02036 3.1e-231 L Integrase core domain
EAFBLIHF_02037 1.3e-139 L Bacterial dnaA protein
EAFBLIHF_02038 7e-159
EAFBLIHF_02039 1.2e-190 L PFAM Integrase catalytic region
EAFBLIHF_02040 1.3e-70 O Preprotein translocase subunit SecB
EAFBLIHF_02041 1.9e-175 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
EAFBLIHF_02042 4.8e-252 mmuP E amino acid
EAFBLIHF_02044 3.2e-11 K transcriptional regulator
EAFBLIHF_02045 9.6e-149 S Protein of unknown function (DUF3800)
EAFBLIHF_02047 0.0 snf 2.7.11.1 KL domain protein
EAFBLIHF_02048 6.6e-159 snf 2.7.11.1 KL domain protein
EAFBLIHF_02049 1.7e-145 ywqE 3.1.3.48 GM PHP domain protein
EAFBLIHF_02050 3e-212 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EAFBLIHF_02051 0.0 sbcC L Putative exonuclease SbcCD, C subunit
EAFBLIHF_02052 8.4e-93 L nuclease
EAFBLIHF_02053 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
EAFBLIHF_02054 5.1e-69
EAFBLIHF_02055 7.5e-103 fic D Fic/DOC family
EAFBLIHF_02056 2.2e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EAFBLIHF_02057 1.5e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
EAFBLIHF_02058 8.4e-31
EAFBLIHF_02059 2.8e-185
EAFBLIHF_02060 1.7e-23
EAFBLIHF_02061 1.8e-289 L Transposase IS66 family
EAFBLIHF_02062 2.3e-65 XK27_01125 L PFAM IS66 Orf2 family protein
EAFBLIHF_02063 5.1e-108 L Psort location Cytoplasmic, score
EAFBLIHF_02064 3.8e-59
EAFBLIHF_02073 1.3e-07
EAFBLIHF_02076 8.9e-77
EAFBLIHF_02077 7.8e-157
EAFBLIHF_02079 3.3e-85 L PFAM transposase IS200-family protein
EAFBLIHF_02080 1.5e-09
EAFBLIHF_02081 3.8e-88 L HNH nucleases
EAFBLIHF_02082 5e-84 L Phage terminase, small subunit
EAFBLIHF_02084 1.5e-09
EAFBLIHF_02085 0.0 S Phage Terminase
EAFBLIHF_02086 4e-223 S Phage portal protein
EAFBLIHF_02087 2.3e-128 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
EAFBLIHF_02088 3.6e-208 S Phage capsid family
EAFBLIHF_02089 4.6e-61 S Phage gp6-like head-tail connector protein
EAFBLIHF_02090 1.2e-58 S Phage head-tail joining protein
EAFBLIHF_02091 5.5e-71 S Bacteriophage HK97-gp10, putative tail-component
EAFBLIHF_02092 3.4e-67 S Protein of unknown function (DUF806)
EAFBLIHF_02093 4.2e-135 S Phage tail tube protein
EAFBLIHF_02094 1.1e-62 S Phage tail assembly chaperone proteins, TAC
EAFBLIHF_02095 0.0 M Phage tail tape measure protein TP901
EAFBLIHF_02096 7.6e-160 S Phage tail protein
EAFBLIHF_02097 0.0 spr M Prophage endopeptidase tail
EAFBLIHF_02098 1.3e-15 spoIVFA GT2,GT4 D peptidase
EAFBLIHF_02101 2.8e-32 S GDSL-like Lipase/Acylhydrolase
EAFBLIHF_02102 2.8e-210
EAFBLIHF_02105 1.5e-76
EAFBLIHF_02107 4.5e-36
EAFBLIHF_02108 1.1e-59 hol S COG5546 Small integral membrane protein
EAFBLIHF_02109 7.4e-177 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EAFBLIHF_02110 2.5e-211 L Belongs to the 'phage' integrase family
EAFBLIHF_02111 1.3e-51
EAFBLIHF_02112 7.6e-30 M Host cell surface-exposed lipoprotein
EAFBLIHF_02113 1e-83 E IrrE N-terminal-like domain
EAFBLIHF_02114 5.3e-72 K Cro/C1-type HTH DNA-binding domain
EAFBLIHF_02115 8e-31 K Helix-turn-helix XRE-family like proteins
EAFBLIHF_02116 5e-142 K BRO family, N-terminal domain
EAFBLIHF_02117 1.8e-17
EAFBLIHF_02140 1.7e-237 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EAFBLIHF_02141 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EAFBLIHF_02142 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EAFBLIHF_02143 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EAFBLIHF_02144 3.8e-206 coiA 3.6.4.12 S Competence protein
EAFBLIHF_02145 1.5e-269 pipD E Dipeptidase
EAFBLIHF_02146 5.1e-116 yjbH Q Thioredoxin
EAFBLIHF_02147 4e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
EAFBLIHF_02148 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EAFBLIHF_02149 2.4e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
EAFBLIHF_02152 2.2e-187 L Transposase IS66 family
EAFBLIHF_02153 4e-96 L Transposase IS66 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)