ORF_ID e_value Gene_name EC_number CAZy COGs Description
KLDDLPHA_00006 5.3e-36 L Transposase IS66 family
KLDDLPHA_00007 1.5e-97 L transposase, IS605 OrfB family
KLDDLPHA_00008 1.9e-56 cadX K Bacterial regulatory protein, arsR family
KLDDLPHA_00009 1.1e-67 cadD P Cadmium resistance transporter
KLDDLPHA_00011 4e-209 L PFAM Integrase catalytic region
KLDDLPHA_00012 7.1e-46 S VRR_NUC
KLDDLPHA_00013 1.6e-73 S Phage plasmid primase, P4
KLDDLPHA_00014 1.1e-51 L Transposase IS200 like
KLDDLPHA_00015 5.5e-185 L transposase, IS605 OrfB family
KLDDLPHA_00016 4.9e-111 lssY 3.6.1.27 I Acid phosphatase homologues
KLDDLPHA_00017 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KLDDLPHA_00018 1.6e-82
KLDDLPHA_00019 2.7e-72 V HNH nucleases
KLDDLPHA_00020 5.7e-92
KLDDLPHA_00021 4.4e-201 2.1.1.72 KL DNA methylase
KLDDLPHA_00022 6e-53 S Psort location Cytoplasmic, score
KLDDLPHA_00023 1.1e-24 S Domain of unknown function (DUF5049)
KLDDLPHA_00024 1.5e-289 S overlaps another CDS with the same product name
KLDDLPHA_00027 2.8e-11 K Antidote-toxin recognition MazE, bacterial antitoxin
KLDDLPHA_00028 1.3e-216 S Phage portal protein
KLDDLPHA_00029 1e-71 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
KLDDLPHA_00030 7.1e-172 S Phage capsid family
KLDDLPHA_00031 2.2e-31 S Phage gp6-like head-tail connector protein
KLDDLPHA_00032 1.9e-46 S Phage head-tail joining protein
KLDDLPHA_00033 4.5e-52 S Bacteriophage holin family
KLDDLPHA_00035 7.7e-118 L Recombinase zinc beta ribbon domain
KLDDLPHA_00036 1.2e-14 S Recombinase
KLDDLPHA_00037 3.8e-197 L Recombinase
KLDDLPHA_00039 4.5e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLDDLPHA_00040 8.7e-187 yegS 2.7.1.107 G Lipid kinase
KLDDLPHA_00041 9.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLDDLPHA_00042 4.1e-278 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KLDDLPHA_00043 5.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLDDLPHA_00044 1.8e-201 camS S sex pheromone
KLDDLPHA_00045 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KLDDLPHA_00046 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KLDDLPHA_00047 1.1e-209 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KLDDLPHA_00048 2.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KLDDLPHA_00049 3e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
KLDDLPHA_00050 8e-140 IQ reductase
KLDDLPHA_00051 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KLDDLPHA_00052 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KLDDLPHA_00053 4.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KLDDLPHA_00054 9.8e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLDDLPHA_00055 3.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLDDLPHA_00056 3.2e-139 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLDDLPHA_00057 1.1e-62 rplQ J Ribosomal protein L17
KLDDLPHA_00058 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLDDLPHA_00059 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KLDDLPHA_00060 6.2e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KLDDLPHA_00061 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KLDDLPHA_00062 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KLDDLPHA_00063 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KLDDLPHA_00064 2.6e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KLDDLPHA_00065 1.3e-62 rplO J Binds to the 23S rRNA
KLDDLPHA_00066 2.9e-24 rpmD J Ribosomal protein L30
KLDDLPHA_00067 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KLDDLPHA_00068 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KLDDLPHA_00069 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLDDLPHA_00070 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KLDDLPHA_00071 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLDDLPHA_00072 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KLDDLPHA_00073 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KLDDLPHA_00074 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KLDDLPHA_00075 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KLDDLPHA_00076 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
KLDDLPHA_00077 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KLDDLPHA_00078 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KLDDLPHA_00079 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KLDDLPHA_00080 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLDDLPHA_00081 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KLDDLPHA_00082 4.9e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KLDDLPHA_00083 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
KLDDLPHA_00084 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLDDLPHA_00085 3.2e-47 rpsJ J Involved in the binding of tRNA to the ribosomes
KLDDLPHA_00087 1.1e-199
KLDDLPHA_00088 8.5e-65 repB L Initiator Replication protein
KLDDLPHA_00090 6.2e-35 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
KLDDLPHA_00091 9.3e-168 arsB 1.20.4.1 P Sodium Bile acid symporter family
KLDDLPHA_00092 4e-27 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLDDLPHA_00093 1.2e-14 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLDDLPHA_00094 1.3e-42 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
KLDDLPHA_00095 4.4e-31 arsB 1.20.4.1 P Sodium Bile acid symporter family
KLDDLPHA_00096 2.4e-12 fhaB M Rib/alpha-like repeat
KLDDLPHA_00097 0.0 tetP J Elongation factor G, domain IV
KLDDLPHA_00099 1.2e-95 L Integrase
KLDDLPHA_00100 2e-53 S Phage derived protein Gp49-like (DUF891)
KLDDLPHA_00101 6.7e-99 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
KLDDLPHA_00102 7.3e-115 K Transcriptional regulator
KLDDLPHA_00103 3.2e-292 M Exporter of polyketide antibiotics
KLDDLPHA_00104 2e-169 yjjC V ABC transporter
KLDDLPHA_00105 1.1e-220 rodA D Belongs to the SEDS family
KLDDLPHA_00106 1e-31 S Protein of unknown function (DUF2969)
KLDDLPHA_00107 4.4e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KLDDLPHA_00108 1.9e-178 mbl D Cell shape determining protein MreB Mrl
KLDDLPHA_00109 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLDDLPHA_00110 1.3e-33 ywzB S Protein of unknown function (DUF1146)
KLDDLPHA_00111 2.9e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KLDDLPHA_00112 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KLDDLPHA_00113 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KLDDLPHA_00114 1.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KLDDLPHA_00115 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLDDLPHA_00116 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KLDDLPHA_00117 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLDDLPHA_00118 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
KLDDLPHA_00119 5.9e-233 pyrP F Permease
KLDDLPHA_00120 4.4e-130 yibF S overlaps another CDS with the same product name
KLDDLPHA_00121 1.7e-191 yibE S overlaps another CDS with the same product name
KLDDLPHA_00122 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLDDLPHA_00123 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KLDDLPHA_00124 1.1e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KLDDLPHA_00125 4e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KLDDLPHA_00126 6.6e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KLDDLPHA_00127 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLDDLPHA_00128 6e-108 tdk 2.7.1.21 F thymidine kinase
KLDDLPHA_00129 6.4e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
KLDDLPHA_00130 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KLDDLPHA_00131 3e-10
KLDDLPHA_00152 1.7e-21
KLDDLPHA_00154 1.7e-10
KLDDLPHA_00161 9e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KLDDLPHA_00162 1.5e-275 lysP E amino acid
KLDDLPHA_00163 4.7e-08 2.3.1.128 J Acetyltransferase (GNAT) domain
KLDDLPHA_00164 9.8e-118 lssY 3.6.1.27 I phosphatase
KLDDLPHA_00165 1.4e-81 S Threonine/Serine exporter, ThrE
KLDDLPHA_00166 2e-127 thrE S Putative threonine/serine exporter
KLDDLPHA_00167 1e-30 cspC K Cold shock protein
KLDDLPHA_00168 1.6e-123 sirR K iron dependent repressor
KLDDLPHA_00169 5.5e-164 czcD P cation diffusion facilitator family transporter
KLDDLPHA_00170 2.5e-116 S membrane
KLDDLPHA_00171 6.4e-109 S VIT family
KLDDLPHA_00172 5.5e-83 usp1 T Belongs to the universal stress protein A family
KLDDLPHA_00173 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLDDLPHA_00174 2.8e-151 glnH ET ABC transporter
KLDDLPHA_00175 2.4e-110 gluC P ABC transporter permease
KLDDLPHA_00176 3.6e-109 glnP P ABC transporter permease
KLDDLPHA_00177 8.3e-221 S CAAX protease self-immunity
KLDDLPHA_00178 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLDDLPHA_00179 7.9e-55
KLDDLPHA_00180 9.8e-74 merR K MerR HTH family regulatory protein
KLDDLPHA_00181 3.6e-269 lmrB EGP Major facilitator Superfamily
KLDDLPHA_00182 2.9e-123 S Domain of unknown function (DUF4811)
KLDDLPHA_00183 1.6e-67 yneR S Belongs to the HesB IscA family
KLDDLPHA_00184 0.0 S membrane
KLDDLPHA_00185 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KLDDLPHA_00186 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KLDDLPHA_00187 6.8e-101 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KLDDLPHA_00188 6.2e-109 gluP 3.4.21.105 S Peptidase, S54 family
KLDDLPHA_00189 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
KLDDLPHA_00190 2.1e-182 glk 2.7.1.2 G Glucokinase
KLDDLPHA_00191 3.4e-67 yqhL P Rhodanese-like protein
KLDDLPHA_00192 5.9e-22 S Protein of unknown function (DUF3042)
KLDDLPHA_00193 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLDDLPHA_00194 4e-264 glnA 6.3.1.2 E glutamine synthetase
KLDDLPHA_00195 4.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLDDLPHA_00196 7e-22 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KLDDLPHA_00197 3.9e-12
KLDDLPHA_00198 2.2e-154 P Belongs to the nlpA lipoprotein family
KLDDLPHA_00199 1.4e-98 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLDDLPHA_00200 4.8e-51 S Iron-sulfur cluster assembly protein
KLDDLPHA_00201 2.6e-150
KLDDLPHA_00202 3.3e-181
KLDDLPHA_00203 2.8e-85 dut S Protein conserved in bacteria
KLDDLPHA_00207 8e-103 K Transcriptional regulator
KLDDLPHA_00208 3.1e-104 L Integrase
KLDDLPHA_00209 1.7e-33 S RelB antitoxin
KLDDLPHA_00210 3e-44
KLDDLPHA_00212 1.9e-204
KLDDLPHA_00213 3.1e-59
KLDDLPHA_00214 2.4e-31 S CAAX protease self-immunity
KLDDLPHA_00215 6e-93 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
KLDDLPHA_00216 2.4e-17 pre D plasmid recombination enzyme
KLDDLPHA_00217 5.7e-231 EGP Sugar (and other) transporter
KLDDLPHA_00218 1e-254 yfnA E Amino Acid
KLDDLPHA_00219 4.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KLDDLPHA_00220 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
KLDDLPHA_00221 9.6e-82 zur P Belongs to the Fur family
KLDDLPHA_00222 4e-17 3.2.1.14 GH18
KLDDLPHA_00223 7.1e-150
KLDDLPHA_00224 1.7e-38 pspC KT positive regulation of macromolecule biosynthetic process
KLDDLPHA_00225 1.7e-93 K Transcriptional regulator (TetR family)
KLDDLPHA_00226 1.7e-219 V domain protein
KLDDLPHA_00227 2.1e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLDDLPHA_00229 6.6e-35 S Transglycosylase associated protein
KLDDLPHA_00230 8.6e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KLDDLPHA_00231 5e-127 3.1.3.73 G phosphoglycerate mutase
KLDDLPHA_00232 2.8e-114 dedA S SNARE associated Golgi protein
KLDDLPHA_00233 0.0 helD 3.6.4.12 L DNA helicase
KLDDLPHA_00234 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
KLDDLPHA_00235 6.2e-157 EG EamA-like transporter family
KLDDLPHA_00236 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KLDDLPHA_00237 3.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
KLDDLPHA_00238 1.3e-218 S cog cog1373
KLDDLPHA_00240 4e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KLDDLPHA_00245 7.6e-34 L Transposase IS66 family
KLDDLPHA_00246 2.1e-31 L Transposase IS66 family
KLDDLPHA_00247 2.9e-210 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KLDDLPHA_00248 6.8e-30 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KLDDLPHA_00249 1.1e-138 S Belongs to the UPF0246 family
KLDDLPHA_00250 1.4e-136 S Membrane
KLDDLPHA_00251 6.8e-74 4.4.1.5 E Glyoxalase
KLDDLPHA_00252 5.1e-84 yueI S Protein of unknown function (DUF1694)
KLDDLPHA_00253 7.9e-233 rarA L recombination factor protein RarA
KLDDLPHA_00254 1.7e-45
KLDDLPHA_00255 4.3e-83 usp6 T universal stress protein
KLDDLPHA_00256 1.4e-203 araR K Transcriptional regulator
KLDDLPHA_00257 7.3e-155 ytbE 1.1.1.346 S Aldo keto reductase
KLDDLPHA_00258 9.2e-29 maa 2.3.1.79 S Maltose O-acetyltransferase
KLDDLPHA_00259 2.2e-50 maa 2.3.1.79 S Maltose O-acetyltransferase
KLDDLPHA_00260 2.2e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KLDDLPHA_00261 1.4e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KLDDLPHA_00262 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
KLDDLPHA_00263 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KLDDLPHA_00264 1.5e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
KLDDLPHA_00265 3.4e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KLDDLPHA_00266 4e-21
KLDDLPHA_00267 1.2e-100
KLDDLPHA_00269 3.2e-53 YPO0284 GM NAD(P)H-binding
KLDDLPHA_00271 5.5e-29 S Protein of unknown function (DUF4065)
KLDDLPHA_00272 4.8e-50 doc S Fic/DOC family
KLDDLPHA_00273 1.8e-09
KLDDLPHA_00275 1.1e-43
KLDDLPHA_00276 1.4e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KLDDLPHA_00277 5.5e-248 mmuP E amino acid
KLDDLPHA_00279 2e-36
KLDDLPHA_00280 1.5e-06 D nuclear chromosome segregation
KLDDLPHA_00281 0.0 snf 2.7.11.1 KL domain protein
KLDDLPHA_00282 5.9e-143 ywqE 3.1.3.48 GM PHP domain protein
KLDDLPHA_00283 4.9e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KLDDLPHA_00284 0.0 sbcC L Putative exonuclease SbcCD, C subunit
KLDDLPHA_00285 2.9e-16 L nuclease
KLDDLPHA_00286 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
KLDDLPHA_00287 7.3e-71
KLDDLPHA_00288 3.1e-101 fic D Fic/DOC family
KLDDLPHA_00289 3.1e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KLDDLPHA_00290 1.7e-151 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KLDDLPHA_00291 1.3e-28
KLDDLPHA_00292 1.3e-146
KLDDLPHA_00293 1.2e-24
KLDDLPHA_00294 6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLDDLPHA_00295 1.8e-166
KLDDLPHA_00296 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLDDLPHA_00297 1.6e-243 purD 6.3.4.13 F Belongs to the GARS family
KLDDLPHA_00298 1e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KLDDLPHA_00299 3.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KLDDLPHA_00300 6.2e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KLDDLPHA_00301 5.8e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KLDDLPHA_00302 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLDDLPHA_00303 3.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLDDLPHA_00304 4.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLDDLPHA_00305 4.4e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KLDDLPHA_00306 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KLDDLPHA_00307 3.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KLDDLPHA_00308 4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KLDDLPHA_00309 8.1e-101 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KLDDLPHA_00310 5.8e-172 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KLDDLPHA_00311 1.3e-186 thrC 4.2.3.1 E Threonine synthase
KLDDLPHA_00312 2.7e-24 K helix_turn_helix, arabinose operon control protein
KLDDLPHA_00313 2.5e-127 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KLDDLPHA_00314 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KLDDLPHA_00315 9.7e-123 L Transposase
KLDDLPHA_00316 4.8e-65 L Transposase
KLDDLPHA_00317 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLDDLPHA_00318 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KLDDLPHA_00319 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KLDDLPHA_00320 1.7e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
KLDDLPHA_00321 8.9e-125 ykiI
KLDDLPHA_00322 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLDDLPHA_00323 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLDDLPHA_00324 1e-110 K Bacterial regulatory proteins, tetR family
KLDDLPHA_00325 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KLDDLPHA_00326 4.4e-77 ctsR K Belongs to the CtsR family
KLDDLPHA_00327 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
KLDDLPHA_00328 1e-154 S Hydrolases of the alpha beta superfamily
KLDDLPHA_00329 1.6e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
KLDDLPHA_00330 5.1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLDDLPHA_00331 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
KLDDLPHA_00332 3.1e-113 yjbH Q Thioredoxin
KLDDLPHA_00333 6.8e-267 pipD E Dipeptidase
KLDDLPHA_00334 1.8e-195 coiA 3.6.4.12 S Competence protein
KLDDLPHA_00335 6.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KLDDLPHA_00336 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KLDDLPHA_00337 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KLDDLPHA_00338 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KLDDLPHA_00339 2e-80 yfnA E amino acid
KLDDLPHA_00340 2.5e-161 yfnA E amino acid
KLDDLPHA_00341 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KLDDLPHA_00342 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KLDDLPHA_00343 7e-40 ylqC S Belongs to the UPF0109 family
KLDDLPHA_00344 6.5e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KLDDLPHA_00345 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLDDLPHA_00346 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KLDDLPHA_00347 1.9e-177 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KLDDLPHA_00348 0.0 smc D Required for chromosome condensation and partitioning
KLDDLPHA_00349 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KLDDLPHA_00350 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLDDLPHA_00351 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KLDDLPHA_00352 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KLDDLPHA_00353 0.0 yloV S DAK2 domain fusion protein YloV
KLDDLPHA_00354 4.7e-58 asp S Asp23 family, cell envelope-related function
KLDDLPHA_00355 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KLDDLPHA_00356 3.5e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
KLDDLPHA_00357 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KLDDLPHA_00358 1.2e-160 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KLDDLPHA_00359 0.0 KLT serine threonine protein kinase
KLDDLPHA_00360 6.1e-129 stp 3.1.3.16 T phosphatase
KLDDLPHA_00361 2.4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KLDDLPHA_00362 1.4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KLDDLPHA_00363 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KLDDLPHA_00364 7.4e-209 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KLDDLPHA_00365 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KLDDLPHA_00366 3.5e-114 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KLDDLPHA_00367 2.1e-52
KLDDLPHA_00368 5.5e-263 recN L May be involved in recombinational repair of damaged DNA
KLDDLPHA_00369 1.6e-76 argR K Regulates arginine biosynthesis genes
KLDDLPHA_00370 3.4e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KLDDLPHA_00371 5.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLDDLPHA_00372 1.3e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLDDLPHA_00373 6.5e-214 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLDDLPHA_00374 4e-148 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KLDDLPHA_00375 8e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLDDLPHA_00376 6.4e-70 yqhY S Asp23 family, cell envelope-related function
KLDDLPHA_00377 6.6e-114 J 2'-5' RNA ligase superfamily
KLDDLPHA_00378 1.5e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KLDDLPHA_00379 2.6e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KLDDLPHA_00380 1.3e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KLDDLPHA_00381 9e-53 ysxB J Cysteine protease Prp
KLDDLPHA_00382 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
KLDDLPHA_00383 6.1e-57
KLDDLPHA_00384 6.3e-38 ykuJ S Protein of unknown function (DUF1797)
KLDDLPHA_00385 5.1e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLDDLPHA_00386 2.9e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
KLDDLPHA_00387 2.1e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KLDDLPHA_00388 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLDDLPHA_00389 2.7e-39 ptsH G phosphocarrier protein HPR
KLDDLPHA_00390 6.4e-27
KLDDLPHA_00391 0.0 clpE O Belongs to the ClpA ClpB family
KLDDLPHA_00392 1.7e-100 S Pfam:DUF3816
KLDDLPHA_00393 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
KLDDLPHA_00394 5.5e-116
KLDDLPHA_00395 3.9e-145 V ABC transporter, ATP-binding protein
KLDDLPHA_00397 2.5e-93 L Integrase
KLDDLPHA_00400 5.2e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
KLDDLPHA_00401 8.3e-34
KLDDLPHA_00402 3.6e-07 L Resolvase, N terminal domain
KLDDLPHA_00403 1.7e-40 sthIM 2.1.1.72 L DNA methylase
KLDDLPHA_00404 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
KLDDLPHA_00405 2.2e-50
KLDDLPHA_00407 3.5e-12
KLDDLPHA_00409 0.0 copB 3.6.3.4 P P-type ATPase
KLDDLPHA_00410 6.5e-75 K Copper transport repressor CopY TcrY
KLDDLPHA_00411 9.9e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KLDDLPHA_00412 3.3e-103 T Ion transport 2 domain protein
KLDDLPHA_00413 0.0 S Bacterial membrane protein YfhO
KLDDLPHA_00414 9.8e-206 G Transporter, major facilitator family protein
KLDDLPHA_00415 7.1e-109 yvrI K sigma factor activity
KLDDLPHA_00416 6.7e-60 ydiI Q Thioesterase superfamily
KLDDLPHA_00417 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KLDDLPHA_00418 2.3e-35 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KLDDLPHA_00419 2.8e-31 feoA P FeoA domain
KLDDLPHA_00420 1.9e-144 sufC O FeS assembly ATPase SufC
KLDDLPHA_00421 5.1e-240 sufD O FeS assembly protein SufD
KLDDLPHA_00422 5.2e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KLDDLPHA_00423 3.6e-79 nifU C SUF system FeS assembly protein, NifU family
KLDDLPHA_00424 3.6e-271 sufB O assembly protein SufB
KLDDLPHA_00425 2.8e-57 yitW S Iron-sulfur cluster assembly protein
KLDDLPHA_00426 2.6e-158 hipB K Helix-turn-helix
KLDDLPHA_00427 5.7e-115 nreC K PFAM regulatory protein LuxR
KLDDLPHA_00429 2.7e-38 S Cytochrome B5
KLDDLPHA_00430 2.7e-154 yitU 3.1.3.104 S hydrolase
KLDDLPHA_00431 2.7e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KLDDLPHA_00432 4e-148 f42a O Band 7 protein
KLDDLPHA_00433 1.3e-45 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
KLDDLPHA_00434 6.2e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLDDLPHA_00435 6.4e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KLDDLPHA_00436 5.7e-186 galR K Periplasmic binding protein-like domain
KLDDLPHA_00437 0.0 rafA 3.2.1.22 G alpha-galactosidase
KLDDLPHA_00438 9.4e-40 L Transposase
KLDDLPHA_00439 1.9e-84
KLDDLPHA_00440 1.3e-168 L Belongs to the 'phage' integrase family
KLDDLPHA_00441 3.1e-19 S Excisionase from transposon Tn916
KLDDLPHA_00444 3.3e-133
KLDDLPHA_00445 1.1e-12 S Helix-turn-helix domain
KLDDLPHA_00447 1e-78 L Resolvase, N terminal domain
KLDDLPHA_00449 3.4e-11 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
KLDDLPHA_00451 5.2e-119 L hmm pf00665
KLDDLPHA_00452 1.3e-94 L Helix-turn-helix domain
KLDDLPHA_00453 8.9e-86
KLDDLPHA_00454 2.8e-74 V HNH nucleases
KLDDLPHA_00455 3.1e-98
KLDDLPHA_00456 2.9e-229 2.1.1.72 KL DNA methylase
KLDDLPHA_00457 3.3e-112 S Psort location Cytoplasmic, score
KLDDLPHA_00458 1.8e-30 S Domain of unknown function (DUF5049)
KLDDLPHA_00459 3e-306 S overlaps another CDS with the same product name
KLDDLPHA_00460 6.3e-243 S Phage portal protein
KLDDLPHA_00461 1.4e-121 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
KLDDLPHA_00462 2.8e-221 S Phage capsid family
KLDDLPHA_00463 4.3e-43 S Phage gp6-like head-tail connector protein
KLDDLPHA_00464 6.9e-68 S Phage head-tail joining protein
KLDDLPHA_00465 3.6e-70 S Bacteriophage holin family
KLDDLPHA_00466 1.2e-20 M Glycosyl hydrolases family 25
KLDDLPHA_00467 3.8e-69 M Glycosyl hydrolases family 25
KLDDLPHA_00468 4.7e-27
KLDDLPHA_00469 2.1e-283 L Recombinase zinc beta ribbon domain
KLDDLPHA_00470 9.1e-284 L Recombinase
KLDDLPHA_00471 1.7e-127 cylA V ABC transporter
KLDDLPHA_00472 3e-124 cylB V ABC-2 type transporter
KLDDLPHA_00473 2.2e-65 K LytTr DNA-binding domain
KLDDLPHA_00474 1.7e-37 S Protein of unknown function (DUF3021)
KLDDLPHA_00476 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KLDDLPHA_00477 4.2e-52 3.1.21.3 V Type I restriction
KLDDLPHA_00478 1.9e-175 xerC L Belongs to the 'phage' integrase family
KLDDLPHA_00479 5.2e-39 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
KLDDLPHA_00480 6.4e-32 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
KLDDLPHA_00481 2.2e-290 2.1.1.72 V type I restriction-modification system
KLDDLPHA_00482 3.9e-23 K Cro/C1-type HTH DNA-binding domain
KLDDLPHA_00483 6.7e-122 F helicase superfamily c-terminal domain
KLDDLPHA_00484 7.2e-16 S Domain of unknown function (DUF1837)
KLDDLPHA_00486 1.1e-22
KLDDLPHA_00487 1.6e-28
KLDDLPHA_00488 9.1e-201 L Protein of unknown function (DUF2800)
KLDDLPHA_00489 9.5e-95 S Protein of unknown function (DUF2815)
KLDDLPHA_00490 3.5e-45 polA_2 2.7.7.7 L DNA polymerase
KLDDLPHA_00491 2.5e-70 S Psort location Cytoplasmic, score
KLDDLPHA_00492 1.5e-97 S Phage plasmid primase, P4
KLDDLPHA_00493 2.1e-45 S VRR_NUC
KLDDLPHA_00494 1.7e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KLDDLPHA_00495 1.4e-222 G Glycosyl hydrolases family 8
KLDDLPHA_00496 1.2e-241 ydaM M Glycosyl transferase
KLDDLPHA_00498 1.2e-139
KLDDLPHA_00499 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
KLDDLPHA_00500 4e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLDDLPHA_00501 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
KLDDLPHA_00502 4.6e-160 pstS P Phosphate
KLDDLPHA_00503 2.8e-50 dedA S SNARE-like domain protein
KLDDLPHA_00504 2.8e-101 S Protein of unknown function (DUF1461)
KLDDLPHA_00505 9.4e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KLDDLPHA_00506 6.6e-93 yutD S Protein of unknown function (DUF1027)
KLDDLPHA_00507 4.7e-111 S Calcineurin-like phosphoesterase
KLDDLPHA_00508 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLDDLPHA_00509 7e-150 ytxK 2.1.1.72 L N-6 DNA Methylase
KLDDLPHA_00510 1e-67
KLDDLPHA_00511 3.2e-41
KLDDLPHA_00512 4.1e-77 NU general secretion pathway protein
KLDDLPHA_00513 7.1e-47 comGC U competence protein ComGC
KLDDLPHA_00514 3e-182 comGB NU type II secretion system
KLDDLPHA_00515 1.3e-182 comGA NU Type II IV secretion system protein
KLDDLPHA_00516 5.9e-132 yebC K Transcriptional regulatory protein
KLDDLPHA_00517 1e-132
KLDDLPHA_00518 7.1e-181 ccpA K catabolite control protein A
KLDDLPHA_00519 1.1e-195 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KLDDLPHA_00520 4.3e-16
KLDDLPHA_00521 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KLDDLPHA_00522 6.9e-148 ykuT M mechanosensitive ion channel
KLDDLPHA_00523 1.8e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
KLDDLPHA_00524 1.1e-74 ykuL S (CBS) domain
KLDDLPHA_00525 3.8e-93 S Phosphoesterase
KLDDLPHA_00526 9.8e-106 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KLDDLPHA_00527 3.1e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KLDDLPHA_00528 1.6e-97 yslB S Protein of unknown function (DUF2507)
KLDDLPHA_00529 6.1e-54 trxA O Belongs to the thioredoxin family
KLDDLPHA_00530 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KLDDLPHA_00531 1.6e-86 cvpA S Colicin V production protein
KLDDLPHA_00532 6.1e-48 yrzB S Belongs to the UPF0473 family
KLDDLPHA_00533 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KLDDLPHA_00534 4.1e-43 yrzL S Belongs to the UPF0297 family
KLDDLPHA_00535 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLDDLPHA_00536 1.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KLDDLPHA_00537 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KLDDLPHA_00538 6.2e-31 yajC U Preprotein translocase
KLDDLPHA_00539 2.2e-188 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KLDDLPHA_00540 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KLDDLPHA_00541 4.3e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KLDDLPHA_00542 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLDDLPHA_00543 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLDDLPHA_00544 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
KLDDLPHA_00545 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KLDDLPHA_00546 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
KLDDLPHA_00547 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLDDLPHA_00548 1.7e-137 ymfM S Helix-turn-helix domain
KLDDLPHA_00549 2.5e-247 ymfH S Peptidase M16
KLDDLPHA_00550 8.1e-227 ymfF S Peptidase M16 inactive domain protein
KLDDLPHA_00551 4.7e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLDDLPHA_00552 3.2e-102 glnP P ABC transporter permease
KLDDLPHA_00553 8.7e-93 mreD M rod shape-determining protein MreD
KLDDLPHA_00554 3.5e-152 mreC M Involved in formation and maintenance of cell shape
KLDDLPHA_00555 1.7e-179 mreB D cell shape determining protein MreB
KLDDLPHA_00556 8e-122 radC L DNA repair protein
KLDDLPHA_00557 2.5e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KLDDLPHA_00558 1.8e-231 ndh 1.6.99.3 C NADH dehydrogenase
KLDDLPHA_00559 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KLDDLPHA_00560 2.3e-311 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KLDDLPHA_00561 4.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KLDDLPHA_00562 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
KLDDLPHA_00563 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KLDDLPHA_00564 3.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLDDLPHA_00565 2.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
KLDDLPHA_00566 3.4e-244 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KLDDLPHA_00567 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KLDDLPHA_00576 4.3e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KLDDLPHA_00577 9.2e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KLDDLPHA_00578 8.4e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KLDDLPHA_00579 1.6e-255 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KLDDLPHA_00580 8.6e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KLDDLPHA_00581 7.6e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KLDDLPHA_00582 1.4e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KLDDLPHA_00583 1.2e-124 IQ reductase
KLDDLPHA_00584 2.9e-152 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KLDDLPHA_00585 1.4e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLDDLPHA_00586 1.8e-168 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLDDLPHA_00587 4.7e-76 marR K Transcriptional regulator, MarR family
KLDDLPHA_00588 8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KLDDLPHA_00590 1.3e-201 xerS L Belongs to the 'phage' integrase family
KLDDLPHA_00591 2.1e-276 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
KLDDLPHA_00592 3.5e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
KLDDLPHA_00593 3e-156 rssA S Phospholipase, patatin family
KLDDLPHA_00594 9.4e-118 L Integrase
KLDDLPHA_00595 4.2e-153 EG EamA-like transporter family
KLDDLPHA_00596 9.6e-129 narI 1.7.5.1 C Nitrate reductase
KLDDLPHA_00597 1.1e-53 narJ C nitrate reductase molybdenum cofactor assembly chaperone
KLDDLPHA_00598 2.6e-33 narJ C nitrate reductase molybdenum cofactor assembly chaperone
KLDDLPHA_00599 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
KLDDLPHA_00600 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KLDDLPHA_00601 5.8e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KLDDLPHA_00602 2.8e-224 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
KLDDLPHA_00603 2e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KLDDLPHA_00604 1.2e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KLDDLPHA_00605 5.7e-228 clcA_2 P Chloride transporter, ClC family
KLDDLPHA_00606 4.8e-139 L PFAM transposase IS116 IS110 IS902
KLDDLPHA_00607 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
KLDDLPHA_00608 1.3e-222 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KLDDLPHA_00609 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
KLDDLPHA_00610 1.3e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KLDDLPHA_00611 1.4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KLDDLPHA_00612 5.3e-78
KLDDLPHA_00613 9.8e-32 ykzG S Belongs to the UPF0356 family
KLDDLPHA_00614 4.3e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
KLDDLPHA_00615 1.3e-28
KLDDLPHA_00616 3.8e-130 mltD CBM50 M NlpC P60 family protein
KLDDLPHA_00618 2.2e-57
KLDDLPHA_00619 3.9e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KLDDLPHA_00620 1.1e-218 EG GntP family permease
KLDDLPHA_00621 8.5e-84 KT Putative sugar diacid recognition
KLDDLPHA_00622 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KLDDLPHA_00623 7.7e-219 patA 2.6.1.1 E Aminotransferase
KLDDLPHA_00624 2.8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KLDDLPHA_00625 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KLDDLPHA_00626 1.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KLDDLPHA_00627 2.4e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KLDDLPHA_00628 4.1e-245 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KLDDLPHA_00629 2.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
KLDDLPHA_00630 1.1e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KLDDLPHA_00631 5.8e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLDDLPHA_00632 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KLDDLPHA_00633 8e-16 S Repeat protein
KLDDLPHA_00634 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
KLDDLPHA_00635 5.3e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KLDDLPHA_00636 7.5e-58 XK27_04120 S Putative amino acid metabolism
KLDDLPHA_00637 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
KLDDLPHA_00638 5.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KLDDLPHA_00640 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KLDDLPHA_00641 4.2e-32 cspA K Cold shock protein
KLDDLPHA_00642 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KLDDLPHA_00643 1e-35 divIVA D DivIVA domain protein
KLDDLPHA_00644 5.4e-144 ylmH S S4 domain protein
KLDDLPHA_00645 8.3e-41 yggT S YGGT family
KLDDLPHA_00646 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KLDDLPHA_00647 7.8e-222 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KLDDLPHA_00648 2.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KLDDLPHA_00649 7.9e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KLDDLPHA_00650 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KLDDLPHA_00651 1.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KLDDLPHA_00652 4.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KLDDLPHA_00653 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KLDDLPHA_00654 1.3e-55 ftsL D Cell division protein FtsL
KLDDLPHA_00655 1.3e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KLDDLPHA_00656 3.1e-77 mraZ K Belongs to the MraZ family
KLDDLPHA_00657 1.9e-56
KLDDLPHA_00658 1.2e-10 S Protein of unknown function (DUF4044)
KLDDLPHA_00659 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KLDDLPHA_00660 2.3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KLDDLPHA_00661 1e-159 rrmA 2.1.1.187 H Methyltransferase
KLDDLPHA_00662 6.6e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KLDDLPHA_00664 2.2e-179 L Transposase IS66 family
KLDDLPHA_00665 4e-276 L Transposase IS66 family
KLDDLPHA_00666 9e-62 XK27_01125 L PFAM IS66 Orf2 family protein
KLDDLPHA_00667 2.8e-69 S Psort location Cytoplasmic, score
KLDDLPHA_00668 1.4e-98 S Protein of unknown function (DUF2815)
KLDDLPHA_00669 4e-212 L Protein of unknown function (DUF2800)
KLDDLPHA_00670 2e-41
KLDDLPHA_00671 8.5e-25
KLDDLPHA_00672 6.5e-73 K DNA-templated transcription, initiation
KLDDLPHA_00673 1.5e-18 S Domain of unknown function (DUF1837)
KLDDLPHA_00674 8.9e-135 F helicase superfamily c-terminal domain
KLDDLPHA_00675 4.9e-23 K Cro/C1-type HTH DNA-binding domain
KLDDLPHA_00676 2.3e-72 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KLDDLPHA_00677 5.1e-139 L Bacterial dnaA protein
KLDDLPHA_00678 1.2e-174 L Integrase core domain
KLDDLPHA_00679 1.9e-86 2.1.1.72, 3.1.21.4 L site-specific DNA-methyltransferase (adenine-specific) activity
KLDDLPHA_00680 0.0 L Type III restriction enzyme, res subunit
KLDDLPHA_00681 5.8e-288 S Protein of unknown function DUF262
KLDDLPHA_00682 8.1e-07
KLDDLPHA_00683 2.6e-25 EGP Sugar (and other) transporter
KLDDLPHA_00684 5.3e-54 U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KLDDLPHA_00685 3.5e-174 S Domain of unknown function (DUF389)
KLDDLPHA_00686 1e-88 L Recombinase
KLDDLPHA_00687 3.3e-71 K DNA binding
KLDDLPHA_00688 1e-120 L helicase activity
KLDDLPHA_00689 4.9e-207 L helicase activity
KLDDLPHA_00691 1.8e-55 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLDDLPHA_00692 2e-163 L PFAM Integrase catalytic region
KLDDLPHA_00693 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KLDDLPHA_00694 7.9e-35 copZ C Heavy-metal-associated domain
KLDDLPHA_00695 1.2e-94 dps P Belongs to the Dps family
KLDDLPHA_00696 5.2e-113 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KLDDLPHA_00697 6.3e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
KLDDLPHA_00698 3.6e-62 5.1.1.13 M Asp/Glu/Hydantoin racemase
KLDDLPHA_00699 2e-22 5.1.1.13 M Asp/Glu/Hydantoin racemase
KLDDLPHA_00700 1.5e-69 L Recombinase
KLDDLPHA_00701 7.6e-67 L Recombinase
KLDDLPHA_00702 3.3e-85 L Recombinase
KLDDLPHA_00703 4.7e-19 L Recombinase zinc beta ribbon domain
KLDDLPHA_00704 1.3e-68 L Recombinase zinc beta ribbon domain
KLDDLPHA_00705 8.2e-19
KLDDLPHA_00706 2.4e-29 S Bacteriophage holin family
KLDDLPHA_00707 7.2e-54 S Phage head-tail joining protein
KLDDLPHA_00708 1.3e-39 S Phage gp6-like head-tail connector protein
KLDDLPHA_00709 8.8e-172 S Phage capsid family
KLDDLPHA_00710 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KLDDLPHA_00711 1.1e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
KLDDLPHA_00712 6.6e-257 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLDDLPHA_00713 1.2e-102 pncA Q Isochorismatase family
KLDDLPHA_00714 1e-111 frnE Q DSBA-like thioredoxin domain
KLDDLPHA_00715 4e-79 I alpha/beta hydrolase fold
KLDDLPHA_00716 8.5e-20 K Helix-turn-helix XRE-family like proteins
KLDDLPHA_00717 4.3e-35 S Phage derived protein Gp49-like (DUF891)
KLDDLPHA_00719 8.9e-41 yrvD S Pfam:DUF1049
KLDDLPHA_00720 9.6e-152 3.1.3.102, 3.1.3.104 S hydrolase
KLDDLPHA_00721 2.1e-90 ntd 2.4.2.6 F Nucleoside
KLDDLPHA_00722 2e-18
KLDDLPHA_00723 2.6e-163 S Alpha/beta hydrolase of unknown function (DUF915)
KLDDLPHA_00724 6.2e-114 yviA S Protein of unknown function (DUF421)
KLDDLPHA_00725 7e-72 S Protein of unknown function (DUF3290)
KLDDLPHA_00726 2.3e-41 ybaN S Protein of unknown function (DUF454)
KLDDLPHA_00727 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLDDLPHA_00728 1.6e-157 endA V DNA/RNA non-specific endonuclease
KLDDLPHA_00729 6.6e-254 yifK E Amino acid permease
KLDDLPHA_00731 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KLDDLPHA_00732 2.3e-229 N Uncharacterized conserved protein (DUF2075)
KLDDLPHA_00733 4.3e-121 S SNARE associated Golgi protein
KLDDLPHA_00734 0.0 uvrA3 L excinuclease ABC, A subunit
KLDDLPHA_00735 5.9e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLDDLPHA_00736 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLDDLPHA_00737 5.4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLDDLPHA_00738 1.1e-144 S DUF218 domain
KLDDLPHA_00739 0.0 ubiB S ABC1 family
KLDDLPHA_00740 7.2e-245 yhdP S Transporter associated domain
KLDDLPHA_00741 5.5e-74 copY K Copper transport repressor CopY TcrY
KLDDLPHA_00742 1.3e-241 EGP Major facilitator Superfamily
KLDDLPHA_00743 1.1e-72 yeaL S UPF0756 membrane protein
KLDDLPHA_00744 1.5e-80 C Flavodoxin
KLDDLPHA_00745 3e-159 K LysR substrate binding domain protein
KLDDLPHA_00746 1.3e-165 1.1.1.346 C Aldo keto reductase
KLDDLPHA_00747 8.7e-71 XK27_08635 S UPF0210 protein
KLDDLPHA_00748 2.2e-72 XK27_08635 S UPF0210 protein
KLDDLPHA_00749 1.5e-94 K Acetyltransferase (GNAT) domain
KLDDLPHA_00750 8.1e-154 S Alpha beta hydrolase
KLDDLPHA_00751 1.8e-156 gspA M family 8
KLDDLPHA_00752 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLDDLPHA_00753 1.5e-89
KLDDLPHA_00754 9.3e-161 degV S EDD domain protein, DegV family
KLDDLPHA_00755 0.0 FbpA K Fibronectin-binding protein
KLDDLPHA_00756 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KLDDLPHA_00757 3.6e-207 carA 6.3.5.5 F Belongs to the CarA family
KLDDLPHA_00758 2.9e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLDDLPHA_00759 1.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KLDDLPHA_00760 1.5e-65 esbA S Family of unknown function (DUF5322)
KLDDLPHA_00761 9e-71 rnhA 3.1.26.4 L Ribonuclease HI
KLDDLPHA_00762 1.1e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KLDDLPHA_00763 3e-81 F Belongs to the NrdI family
KLDDLPHA_00764 1.2e-42 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KLDDLPHA_00765 3.2e-101 ypsA S Belongs to the UPF0398 family
KLDDLPHA_00766 5.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KLDDLPHA_00767 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KLDDLPHA_00768 1.3e-160 EG EamA-like transporter family
KLDDLPHA_00769 8.1e-123 dnaD L DnaD domain protein
KLDDLPHA_00770 6.9e-87 ypmB S Protein conserved in bacteria
KLDDLPHA_00771 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KLDDLPHA_00772 6.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KLDDLPHA_00773 7.4e-167 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KLDDLPHA_00774 1.8e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KLDDLPHA_00775 6.4e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KLDDLPHA_00776 2.5e-86 S Protein of unknown function (DUF1440)
KLDDLPHA_00777 8.5e-34
KLDDLPHA_00778 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
KLDDLPHA_00779 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
KLDDLPHA_00780 3.8e-10
KLDDLPHA_00781 5.7e-186 lacR K Transcriptional regulator
KLDDLPHA_00782 0.0 lacS G Transporter
KLDDLPHA_00783 0.0 lacZ 3.2.1.23 G -beta-galactosidase
KLDDLPHA_00784 9.3e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLDDLPHA_00785 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KLDDLPHA_00786 8.9e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KLDDLPHA_00787 2.7e-222 mdtG EGP Major facilitator Superfamily
KLDDLPHA_00788 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
KLDDLPHA_00789 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLDDLPHA_00791 3.6e-111 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KLDDLPHA_00792 6.3e-141 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KLDDLPHA_00793 3.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
KLDDLPHA_00794 0.0 trxB2 1.8.1.9 C Thioredoxin domain
KLDDLPHA_00795 4.2e-272 pipD E Dipeptidase
KLDDLPHA_00796 7.3e-293 yjbQ P TrkA C-terminal domain protein
KLDDLPHA_00797 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KLDDLPHA_00798 3.3e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KLDDLPHA_00799 3.2e-89
KLDDLPHA_00800 8.1e-35
KLDDLPHA_00801 2.3e-08 K Transcriptional regulator, HxlR family
KLDDLPHA_00802 2.9e-166 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KLDDLPHA_00803 7.4e-142 epsB M biosynthesis protein
KLDDLPHA_00804 4.1e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KLDDLPHA_00805 4e-138 cps2D 5.1.3.2 M RmlD substrate binding domain
KLDDLPHA_00806 3.8e-90 tuaA M Bacterial sugar transferase
KLDDLPHA_00807 3.5e-42 tuaG GT2 M Glycosyltransferase like family 2
KLDDLPHA_00808 3.2e-44 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
KLDDLPHA_00809 5.5e-51 waaB GT4 M Glycosyl transferases group 1
KLDDLPHA_00810 1.3e-35 M Glycosyltransferase, group 2 family protein
KLDDLPHA_00811 9.7e-58 M Glycosyltransferase like family 2
KLDDLPHA_00813 6.8e-108 S Polysaccharide biosynthesis protein
KLDDLPHA_00814 4e-45 MA20_17390 GT4 M Glycosyl transferases group 1
KLDDLPHA_00815 5.7e-81 tagB 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KLDDLPHA_00816 3.5e-83 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
KLDDLPHA_00817 3e-97 4.1.1.35 M Male sterility protein
KLDDLPHA_00818 2.1e-69 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KLDDLPHA_00819 2.7e-157 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KLDDLPHA_00821 5.1e-165 L Integrase core domain
KLDDLPHA_00822 1.4e-57 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KLDDLPHA_00824 3.4e-76 S SIR2-like domain
KLDDLPHA_00825 7.4e-103 S Domain of unknown function DUF87
KLDDLPHA_00826 5.3e-45 3.2.1.18 GH33 M Rib/alpha-like repeat
KLDDLPHA_00832 2.2e-07 S Domain of unknown function (DUF3173)
KLDDLPHA_00833 4.3e-87 L Belongs to the 'phage' integrase family
KLDDLPHA_00834 1.2e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
KLDDLPHA_00835 3.7e-10 dnaQ 2.7.7.7 L Psort location Cytoplasmic, score 8.87
KLDDLPHA_00836 8.5e-10 L Resolvase, N terminal domain
KLDDLPHA_00837 9.8e-79 L Resolvase, N terminal domain
KLDDLPHA_00838 5.3e-125
KLDDLPHA_00839 0.0
KLDDLPHA_00841 1.4e-33 S Domain of unknown function (DUF3173)
KLDDLPHA_00842 4.9e-229 L Belongs to the 'phage' integrase family
KLDDLPHA_00843 2.9e-224 oxlT P Major Facilitator Superfamily
KLDDLPHA_00844 2.1e-160 spoU 2.1.1.185 J Methyltransferase
KLDDLPHA_00845 3.4e-92 ywlG S Belongs to the UPF0340 family
KLDDLPHA_00846 1.5e-42 wecD3 K PFAM GCN5-related N-acetyltransferase
KLDDLPHA_00847 3.3e-37 ltrA S Bacterial low temperature requirement A protein (LtrA)
KLDDLPHA_00848 1.5e-40 ltrA S Bacterial low temperature requirement A protein (LtrA)
KLDDLPHA_00849 8.2e-205 cytX U Belongs to the purine-cytosine permease (2.A.39) family
KLDDLPHA_00850 4.3e-13
KLDDLPHA_00851 9.5e-39 S Cytochrome B5
KLDDLPHA_00852 1.3e-16 L Transposase
KLDDLPHA_00853 1e-36 L Helix-turn-helix domain
KLDDLPHA_00854 6e-16 L Helix-turn-helix domain
KLDDLPHA_00855 3.9e-122 O Zinc-dependent metalloprotease
KLDDLPHA_00856 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KLDDLPHA_00857 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
KLDDLPHA_00860 6.4e-183 S Phosphotransferase system, EIIC
KLDDLPHA_00861 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLDDLPHA_00862 3.9e-182
KLDDLPHA_00863 4.7e-63 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLDDLPHA_00864 3.7e-70 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
KLDDLPHA_00865 4e-83 manA 5.3.1.8 G mannose-6-phosphate isomerase
KLDDLPHA_00866 1.2e-97 2.3.1.128 K acetyltransferase
KLDDLPHA_00867 3.9e-187
KLDDLPHA_00868 1.4e-12 K Transcriptional regulator, HxlR family
KLDDLPHA_00869 3.7e-40 L Transposase
KLDDLPHA_00870 2.4e-36 L Transposase
KLDDLPHA_00871 2.6e-17 L Transposase
KLDDLPHA_00872 3.9e-47 L Transposase
KLDDLPHA_00873 1.6e-171 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLDDLPHA_00874 5.4e-48 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KLDDLPHA_00875 3.7e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KLDDLPHA_00876 2.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLDDLPHA_00877 1.1e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KLDDLPHA_00878 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLDDLPHA_00879 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLDDLPHA_00880 2.4e-251 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KLDDLPHA_00881 9.8e-67 yabR J RNA binding
KLDDLPHA_00882 8.1e-55 divIC D Septum formation initiator
KLDDLPHA_00883 6.2e-39 yabO J S4 domain protein
KLDDLPHA_00884 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KLDDLPHA_00885 1.6e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KLDDLPHA_00886 6.9e-113 S (CBS) domain
KLDDLPHA_00887 6.4e-145 tesE Q hydratase
KLDDLPHA_00888 2.3e-242 codA 3.5.4.1 F cytosine deaminase
KLDDLPHA_00889 3.1e-251 U Belongs to the purine-cytosine permease (2.A.39) family
KLDDLPHA_00890 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
KLDDLPHA_00891 3.4e-208 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KLDDLPHA_00892 3.2e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KLDDLPHA_00894 8.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLDDLPHA_00895 3.9e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
KLDDLPHA_00896 1.1e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLDDLPHA_00897 1.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KLDDLPHA_00898 4.9e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
KLDDLPHA_00899 3.6e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KLDDLPHA_00900 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KLDDLPHA_00901 7.5e-158 htpX O Belongs to the peptidase M48B family
KLDDLPHA_00902 7e-93 lemA S LemA family
KLDDLPHA_00903 8e-87 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLDDLPHA_00904 2.7e-120 pgm3 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KLDDLPHA_00905 1.3e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KLDDLPHA_00906 9.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLDDLPHA_00907 8.8e-158 3.2.1.55 GH51 G Right handed beta helix region
KLDDLPHA_00908 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KLDDLPHA_00909 7.3e-116 srtA 3.4.22.70 M sortase family
KLDDLPHA_00910 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
KLDDLPHA_00911 5.4e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLDDLPHA_00912 4.6e-41 rpmE2 J Ribosomal protein L31
KLDDLPHA_00913 2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLDDLPHA_00914 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KLDDLPHA_00915 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KLDDLPHA_00916 5.2e-53 ywiB S Domain of unknown function (DUF1934)
KLDDLPHA_00917 3.4e-149 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
KLDDLPHA_00918 1e-270 ywfO S HD domain protein
KLDDLPHA_00919 6.1e-146 yxeH S hydrolase
KLDDLPHA_00920 9e-48
KLDDLPHA_00921 4.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLDDLPHA_00922 9.2e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KLDDLPHA_00923 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KLDDLPHA_00924 4.7e-127 znuB U ABC 3 transport family
KLDDLPHA_00925 2.2e-122 fhuC P ABC transporter
KLDDLPHA_00926 9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
KLDDLPHA_00927 6.9e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KLDDLPHA_00928 6.8e-37 veg S Biofilm formation stimulator VEG
KLDDLPHA_00929 1e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KLDDLPHA_00930 1.2e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KLDDLPHA_00931 1e-153 tatD L hydrolase, TatD family
KLDDLPHA_00932 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLDDLPHA_00933 1.2e-160 yunF F Protein of unknown function DUF72
KLDDLPHA_00935 4e-130 cobB K SIR2 family
KLDDLPHA_00936 8.6e-176
KLDDLPHA_00937 9.1e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KLDDLPHA_00938 4.6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KLDDLPHA_00939 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLDDLPHA_00940 2.1e-182 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KLDDLPHA_00941 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
KLDDLPHA_00942 0.0 helD 3.6.4.12 L DNA helicase
KLDDLPHA_00943 4.5e-203 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KLDDLPHA_00945 2e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KLDDLPHA_00946 5.7e-264 yfnA E amino acid
KLDDLPHA_00947 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KLDDLPHA_00948 8.9e-41 1.3.5.4 S FMN binding
KLDDLPHA_00949 8.3e-221 norA EGP Major facilitator Superfamily
KLDDLPHA_00950 5.3e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KLDDLPHA_00951 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
KLDDLPHA_00952 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLDDLPHA_00953 3.1e-103 metI P ABC transporter permease
KLDDLPHA_00954 1.5e-15 clcA P chloride
KLDDLPHA_00955 1.2e-95 clcA P chloride
KLDDLPHA_00956 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KLDDLPHA_00957 1.9e-102 proW P ABC transporter, permease protein
KLDDLPHA_00958 6.5e-142 proV E ABC transporter, ATP-binding protein
KLDDLPHA_00959 2.4e-108 proWZ P ABC transporter permease
KLDDLPHA_00960 7e-164 proX M ABC transporter, substrate-binding protein, QAT family
KLDDLPHA_00961 8.4e-73 K Transcriptional regulator
KLDDLPHA_00962 1.9e-51 1.6.5.2 GM NAD(P)H-binding
KLDDLPHA_00963 1.6e-35 1.6.5.2 GM NAD(P)H-binding
KLDDLPHA_00965 1.1e-220 5.4.2.7 G Metalloenzyme superfamily
KLDDLPHA_00966 2.5e-311 cadA P P-type ATPase
KLDDLPHA_00967 1.3e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KLDDLPHA_00968 2.3e-125
KLDDLPHA_00969 2.6e-52 S Sugar efflux transporter for intercellular exchange
KLDDLPHA_00970 8.5e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KLDDLPHA_00972 0.0 L Helicase C-terminal domain protein
KLDDLPHA_00973 1.6e-64 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
KLDDLPHA_00974 1.8e-178 S Aldo keto reductase
KLDDLPHA_00976 1.4e-26 psiE S Phosphate-starvation-inducible E
KLDDLPHA_00977 1.2e-97 ydeN S Serine hydrolase
KLDDLPHA_00979 1.1e-181 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KLDDLPHA_00980 1.2e-253 nhaC C Na H antiporter NhaC
KLDDLPHA_00981 1.1e-36 S Cytochrome b5-like Heme/Steroid binding domain
KLDDLPHA_00982 7.3e-107 ywnB S NAD(P)H-binding
KLDDLPHA_00983 1.2e-114 L PFAM Integrase catalytic region
KLDDLPHA_00986 3.5e-175 MA20_14895 S Conserved hypothetical protein 698
KLDDLPHA_00987 1.9e-145 K LysR substrate binding domain
KLDDLPHA_00988 6.4e-96 V VanZ like family
KLDDLPHA_00990 6e-26
KLDDLPHA_00992 5.2e-146 L Transposase and inactivated derivatives IS30 family
KLDDLPHA_00994 8.7e-113 fic S Fic/DOC family
KLDDLPHA_00995 2e-129 L Belongs to the 'phage' integrase family
KLDDLPHA_00996 4e-19
KLDDLPHA_00999 2.2e-153
KLDDLPHA_01001 1.6e-76 L Resolvase, N terminal domain
KLDDLPHA_01002 2.2e-10 L Resolvase, N terminal domain
KLDDLPHA_01003 6.3e-13 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KLDDLPHA_01007 9.8e-15 K Cro/C1-type HTH DNA-binding domain
KLDDLPHA_01009 2e-184 S PglZ domain
KLDDLPHA_01010 2.6e-49 doc S Fic/DOC family
KLDDLPHA_01012 2.8e-296 2.1.1.72 LV Eco57I restriction-modification methylase
KLDDLPHA_01013 1e-221 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
KLDDLPHA_01014 1.7e-49 S Domain of unknown function (DUF1788)
KLDDLPHA_01015 4.4e-45 S Putative inner membrane protein (DUF1819)
KLDDLPHA_01017 5.5e-101 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KLDDLPHA_01018 1e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLDDLPHA_01019 1.7e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KLDDLPHA_01020 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KLDDLPHA_01021 5.3e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLDDLPHA_01022 2.9e-162 xerD D recombinase XerD
KLDDLPHA_01023 3.3e-166 cvfB S S1 domain
KLDDLPHA_01024 3.6e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KLDDLPHA_01025 0.0 dnaE 2.7.7.7 L DNA polymerase
KLDDLPHA_01026 2e-29 S Protein of unknown function (DUF2929)
KLDDLPHA_01027 2.8e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KLDDLPHA_01028 1.1e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KLDDLPHA_01029 6.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KLDDLPHA_01030 2.4e-220 patA 2.6.1.1 E Aminotransferase
KLDDLPHA_01031 2.9e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KLDDLPHA_01032 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KLDDLPHA_01033 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KLDDLPHA_01034 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KLDDLPHA_01035 3.8e-145 recO L Involved in DNA repair and RecF pathway recombination
KLDDLPHA_01036 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KLDDLPHA_01037 2.1e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KLDDLPHA_01038 3.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KLDDLPHA_01039 3.2e-181 phoH T phosphate starvation-inducible protein PhoH
KLDDLPHA_01040 1.4e-170 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KLDDLPHA_01041 1.5e-82 bioY S BioY family
KLDDLPHA_01042 6e-263 argH 4.3.2.1 E argininosuccinate lyase
KLDDLPHA_01043 1.7e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KLDDLPHA_01044 3.7e-96 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KLDDLPHA_01045 7.8e-73 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KLDDLPHA_01046 8.6e-70 yqeY S YqeY-like protein
KLDDLPHA_01047 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KLDDLPHA_01048 1.1e-262 glnPH2 P ABC transporter permease
KLDDLPHA_01049 1e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLDDLPHA_01050 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KLDDLPHA_01051 4.6e-165 yniA G Phosphotransferase enzyme family
KLDDLPHA_01052 1.9e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KLDDLPHA_01053 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KLDDLPHA_01054 9.4e-50
KLDDLPHA_01055 9.7e-127 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KLDDLPHA_01056 3.1e-178 prmA J Ribosomal protein L11 methyltransferase
KLDDLPHA_01057 7.5e-58
KLDDLPHA_01059 1.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLDDLPHA_01061 3.9e-139 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KLDDLPHA_01062 2e-274 pipD E Dipeptidase
KLDDLPHA_01063 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KLDDLPHA_01064 9.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KLDDLPHA_01065 0.0 dnaK O Heat shock 70 kDa protein
KLDDLPHA_01066 1e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KLDDLPHA_01067 1e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KLDDLPHA_01068 2.9e-63
KLDDLPHA_01069 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KLDDLPHA_01070 2.7e-163 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KLDDLPHA_01071 6.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KLDDLPHA_01072 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KLDDLPHA_01073 1.3e-48 ylxQ J ribosomal protein
KLDDLPHA_01074 1e-44 ylxR K Protein of unknown function (DUF448)
KLDDLPHA_01075 1.4e-215 nusA K Participates in both transcription termination and antitermination
KLDDLPHA_01076 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
KLDDLPHA_01077 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLDDLPHA_01078 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KLDDLPHA_01079 4.1e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KLDDLPHA_01080 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
KLDDLPHA_01081 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KLDDLPHA_01082 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KLDDLPHA_01083 8.2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KLDDLPHA_01084 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KLDDLPHA_01085 4.6e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
KLDDLPHA_01086 7e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLDDLPHA_01087 7.1e-49 yazA L GIY-YIG catalytic domain protein
KLDDLPHA_01088 3.5e-140 yabB 2.1.1.223 L Methyltransferase small domain
KLDDLPHA_01089 1.6e-117 plsC 2.3.1.51 I Acyltransferase
KLDDLPHA_01090 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
KLDDLPHA_01091 1.3e-35 ynzC S UPF0291 protein
KLDDLPHA_01092 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KLDDLPHA_01093 1.3e-210 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KLDDLPHA_01094 1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLDDLPHA_01099 4.1e-55
KLDDLPHA_01101 6.2e-99 S D5 N terminal like
KLDDLPHA_01102 3.1e-51 S Bifunctional DNA primase/polymerase, N-terminal
KLDDLPHA_01104 8.5e-08
KLDDLPHA_01107 4e-21 S Helix-turn-helix domain
KLDDLPHA_01108 1.1e-16 K Transcriptional regulator
KLDDLPHA_01109 1e-09 M LysM domain
KLDDLPHA_01110 1.9e-134 L Belongs to the 'phage' integrase family
KLDDLPHA_01111 4.3e-88
KLDDLPHA_01112 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KLDDLPHA_01113 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KLDDLPHA_01114 5.5e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KLDDLPHA_01115 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KLDDLPHA_01116 4.8e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLDDLPHA_01117 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KLDDLPHA_01118 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
KLDDLPHA_01119 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
KLDDLPHA_01120 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KLDDLPHA_01121 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KLDDLPHA_01122 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLDDLPHA_01123 7.1e-164 S Tetratricopeptide repeat
KLDDLPHA_01124 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLDDLPHA_01125 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KLDDLPHA_01126 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
KLDDLPHA_01127 3.1e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
KLDDLPHA_01128 0.0 comEC S Competence protein ComEC
KLDDLPHA_01129 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
KLDDLPHA_01130 5.8e-80 comEA L Competence protein ComEA
KLDDLPHA_01131 1.9e-197 ylbL T Belongs to the peptidase S16 family
KLDDLPHA_01132 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KLDDLPHA_01133 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KLDDLPHA_01134 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KLDDLPHA_01135 7.7e-222 ftsW D Belongs to the SEDS family
KLDDLPHA_01136 0.0 typA T GTP-binding protein TypA
KLDDLPHA_01137 1.3e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KLDDLPHA_01138 1.9e-46 yktA S Belongs to the UPF0223 family
KLDDLPHA_01139 7.5e-194 ypbB 5.1.3.1 S Helix-turn-helix domain
KLDDLPHA_01140 8.4e-268 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
KLDDLPHA_01141 2.5e-13 M Lysin motif
KLDDLPHA_01142 7.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KLDDLPHA_01143 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
KLDDLPHA_01144 9.4e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KLDDLPHA_01145 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KLDDLPHA_01146 1.4e-234 S Tetratricopeptide repeat protein
KLDDLPHA_01147 8.2e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KLDDLPHA_01148 0.0 yfmR S ABC transporter, ATP-binding protein
KLDDLPHA_01149 7.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLDDLPHA_01150 9.6e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KLDDLPHA_01151 1.9e-110 hlyIII S protein, hemolysin III
KLDDLPHA_01152 4.9e-151 DegV S EDD domain protein, DegV family
KLDDLPHA_01153 2.4e-167 ypmR E lipolytic protein G-D-S-L family
KLDDLPHA_01154 2.8e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
KLDDLPHA_01155 4.4e-35 yozE S Belongs to the UPF0346 family
KLDDLPHA_01156 5.4e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KLDDLPHA_01157 5.1e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLDDLPHA_01158 2.1e-160 dprA LU DNA protecting protein DprA
KLDDLPHA_01159 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLDDLPHA_01160 2.4e-164 lacX 5.1.3.3 G Aldose 1-epimerase
KLDDLPHA_01161 1.2e-104 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KLDDLPHA_01162 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLDDLPHA_01163 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLDDLPHA_01164 8.1e-79 F NUDIX domain
KLDDLPHA_01165 3.9e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
KLDDLPHA_01166 2.7e-67 yqkB S Belongs to the HesB IscA family
KLDDLPHA_01167 1.1e-25
KLDDLPHA_01169 1.6e-85 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
KLDDLPHA_01170 6.9e-60 asp S Asp23 family, cell envelope-related function
KLDDLPHA_01171 6.1e-25
KLDDLPHA_01172 2.6e-92
KLDDLPHA_01173 3.7e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KLDDLPHA_01174 2.1e-180 K Transcriptional regulator, LacI family
KLDDLPHA_01175 1.2e-197 gntT EG Gluconate
KLDDLPHA_01176 3.7e-235 int L COG1961 Site-specific recombinases, DNA invertase Pin homologs
KLDDLPHA_01177 1.9e-53 S Domain of unknown function DUF1829
KLDDLPHA_01178 2.3e-35
KLDDLPHA_01180 4.1e-21 E Zn peptidase
KLDDLPHA_01181 7.5e-49 ps115 K Helix-turn-helix XRE-family like proteins
KLDDLPHA_01182 2.6e-13
KLDDLPHA_01183 1.1e-120 K BRO family, N-terminal domain
KLDDLPHA_01190 4e-43 S ERF superfamily
KLDDLPHA_01191 2.4e-84 S Putative HNHc nuclease
KLDDLPHA_01192 9.2e-21 L Single-stranded DNA-binding protein
KLDDLPHA_01193 5.5e-30 ybl78 L DnaD domain protein
KLDDLPHA_01194 5.7e-40 dnaC 3.4.21.53 L IstB-like ATP binding protein
KLDDLPHA_01198 1e-50 S Protein of unknown function (DUF1064)
KLDDLPHA_01201 1.7e-27
KLDDLPHA_01207 2.5e-33
KLDDLPHA_01208 1.2e-66 gepA K Protein of unknown function (DUF4065)
KLDDLPHA_01209 3.2e-21
KLDDLPHA_01210 1.4e-10
KLDDLPHA_01212 2.1e-08
KLDDLPHA_01213 5.7e-147 L HNH nucleases
KLDDLPHA_01214 3.4e-77 terS L Phage terminase, small subunit
KLDDLPHA_01215 0.0 terL S overlaps another CDS with the same product name
KLDDLPHA_01217 8.4e-240 S Phage portal protein
KLDDLPHA_01218 2.4e-113 pi136 S Caudovirus prohead serine protease
KLDDLPHA_01219 2.7e-160 S Phage capsid family
KLDDLPHA_01220 3.3e-68 S Phage gp6-like head-tail connector protein
KLDDLPHA_01221 1.9e-39 S Phage head-tail joining protein
KLDDLPHA_01222 2.5e-62 S Bacteriophage HK97-gp10, putative tail-component
KLDDLPHA_01223 7.5e-76
KLDDLPHA_01224 8e-114
KLDDLPHA_01225 7.9e-23
KLDDLPHA_01226 1.5e-19
KLDDLPHA_01227 0.0 M Phage tail tape measure protein TP901
KLDDLPHA_01228 2.5e-136 S Phage tail protein
KLDDLPHA_01229 1.7e-212 3.4.24.40 M Peptidase family M23
KLDDLPHA_01231 2.6e-99 S Domain of unknown function (DUF2479)
KLDDLPHA_01235 4.2e-33
KLDDLPHA_01236 6e-45 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KLDDLPHA_01237 3e-149 M Glycosyl hydrolases family 25
KLDDLPHA_01238 5.5e-19
KLDDLPHA_01239 3e-292 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KLDDLPHA_01240 2.9e-96 K Acetyltransferase (GNAT) domain
KLDDLPHA_01241 5.4e-20
KLDDLPHA_01242 2.4e-22
KLDDLPHA_01243 2.2e-44
KLDDLPHA_01244 7e-57 yhaI S Protein of unknown function (DUF805)
KLDDLPHA_01245 1e-33 3.2.1.17 LO Uncharacterized conserved protein (DUF2075)
KLDDLPHA_01246 0.0 L PLD-like domain
KLDDLPHA_01257 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
KLDDLPHA_01258 2.2e-152 lmrB EGP Major facilitator Superfamily
KLDDLPHA_01259 2.5e-57 lmrB EGP Major facilitator Superfamily
KLDDLPHA_01260 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KLDDLPHA_01261 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLDDLPHA_01262 1e-159 sufD O Uncharacterized protein family (UPF0051)
KLDDLPHA_01263 2e-42 lytE M LysM domain protein
KLDDLPHA_01264 0.0 oppD EP Psort location Cytoplasmic, score
KLDDLPHA_01265 1.2e-86 lytE M LysM domain protein
KLDDLPHA_01266 3e-98 xth 3.1.11.2 L exodeoxyribonuclease III
KLDDLPHA_01267 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KLDDLPHA_01268 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
KLDDLPHA_01269 5.3e-153 yeaE S Aldo keto
KLDDLPHA_01270 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
KLDDLPHA_01271 1.2e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
KLDDLPHA_01272 2.5e-77 S Psort location Cytoplasmic, score
KLDDLPHA_01273 1.6e-54 S Short repeat of unknown function (DUF308)
KLDDLPHA_01274 1e-23
KLDDLPHA_01275 1.7e-102 V VanZ like family
KLDDLPHA_01276 7.7e-231 cycA E Amino acid permease
KLDDLPHA_01277 2.8e-84 perR P Belongs to the Fur family
KLDDLPHA_01278 1e-257 EGP Major facilitator Superfamily
KLDDLPHA_01279 7.9e-94 tag 3.2.2.20 L glycosylase
KLDDLPHA_01280 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KLDDLPHA_01281 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLDDLPHA_01282 7.6e-42
KLDDLPHA_01283 1.1e-300 ytgP S Polysaccharide biosynthesis protein
KLDDLPHA_01284 5.4e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KLDDLPHA_01285 8.1e-276 pepV 3.5.1.18 E dipeptidase PepV
KLDDLPHA_01286 7.3e-86 uspA T Belongs to the universal stress protein A family
KLDDLPHA_01287 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLDDLPHA_01288 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
KLDDLPHA_01289 1.5e-112
KLDDLPHA_01290 1.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
KLDDLPHA_01291 1.5e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLDDLPHA_01292 1.8e-31
KLDDLPHA_01293 3.6e-109 S CAAX protease self-immunity
KLDDLPHA_01294 1.9e-43
KLDDLPHA_01296 6.4e-69
KLDDLPHA_01297 2.6e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KLDDLPHA_01298 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KLDDLPHA_01299 6.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
KLDDLPHA_01300 1e-221 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KLDDLPHA_01301 1.6e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
KLDDLPHA_01302 3.4e-211 folP 2.5.1.15 H dihydropteroate synthase
KLDDLPHA_01303 5.1e-43
KLDDLPHA_01304 1.6e-39
KLDDLPHA_01306 1.9e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLDDLPHA_01307 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KLDDLPHA_01308 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KLDDLPHA_01309 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KLDDLPHA_01310 9.4e-38 yheA S Belongs to the UPF0342 family
KLDDLPHA_01311 1.3e-218 yhaO L Ser Thr phosphatase family protein
KLDDLPHA_01312 0.0 L AAA domain
KLDDLPHA_01313 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KLDDLPHA_01314 3.2e-77 hit FG histidine triad
KLDDLPHA_01315 3.9e-136 ecsA V ABC transporter, ATP-binding protein
KLDDLPHA_01316 1.3e-218 ecsB U ABC transporter
KLDDLPHA_01317 1.2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KLDDLPHA_01318 3.1e-22 S YSIRK type signal peptide
KLDDLPHA_01319 1.3e-10 glsA 3.5.1.2 E Belongs to the glutaminase family
KLDDLPHA_01320 1.8e-56 ytzB S Small secreted protein
KLDDLPHA_01321 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KLDDLPHA_01322 5e-119 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLDDLPHA_01323 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KLDDLPHA_01324 1.9e-119 ybhL S Belongs to the BI1 family
KLDDLPHA_01325 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLDDLPHA_01326 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KLDDLPHA_01327 1.7e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KLDDLPHA_01328 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLDDLPHA_01329 5.9e-223 dnaB L replication initiation and membrane attachment
KLDDLPHA_01330 1.9e-172 dnaI L Primosomal protein DnaI
KLDDLPHA_01331 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KLDDLPHA_01332 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KLDDLPHA_01333 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KLDDLPHA_01334 2.4e-95 yqeG S HAD phosphatase, family IIIA
KLDDLPHA_01335 4.8e-218 yqeH S Ribosome biogenesis GTPase YqeH
KLDDLPHA_01336 1.9e-47 yhbY J RNA-binding protein
KLDDLPHA_01337 4.5e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KLDDLPHA_01338 6.2e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KLDDLPHA_01339 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KLDDLPHA_01340 9.7e-135 yqeM Q Methyltransferase
KLDDLPHA_01341 5.3e-209 ylbM S Belongs to the UPF0348 family
KLDDLPHA_01342 4.9e-99 yceD S Uncharacterized ACR, COG1399
KLDDLPHA_01343 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KLDDLPHA_01344 1.5e-121 K response regulator
KLDDLPHA_01345 4.1e-278 arlS 2.7.13.3 T Histidine kinase
KLDDLPHA_01346 7.4e-267 yjeM E Amino Acid
KLDDLPHA_01347 2.9e-235 V MatE
KLDDLPHA_01348 1.3e-67 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KLDDLPHA_01349 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLDDLPHA_01350 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KLDDLPHA_01351 1.8e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLDDLPHA_01352 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLDDLPHA_01353 6.7e-59 yodB K Transcriptional regulator, HxlR family
KLDDLPHA_01354 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLDDLPHA_01355 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLDDLPHA_01356 5.6e-115 rlpA M PFAM NLP P60 protein
KLDDLPHA_01357 2.3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
KLDDLPHA_01358 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLDDLPHA_01359 0.0 bamA GM domain, Protein
KLDDLPHA_01360 0.0 S Peptidase, M23
KLDDLPHA_01361 0.0 M NlpC/P60 family
KLDDLPHA_01362 3.1e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KLDDLPHA_01363 4e-225 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KLDDLPHA_01364 7.4e-163 yueF S AI-2E family transporter
KLDDLPHA_01365 3.3e-166 csd1 3.5.1.28 G domain, Protein
KLDDLPHA_01366 1.9e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KLDDLPHA_01367 2.1e-69 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KLDDLPHA_01368 1.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KLDDLPHA_01369 9.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KLDDLPHA_01370 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLDDLPHA_01371 1.8e-134
KLDDLPHA_01372 1.2e-145 rfbJ M Glycosyl transferase family 2
KLDDLPHA_01373 5.8e-83
KLDDLPHA_01374 2.6e-72 S Acyltransferase family
KLDDLPHA_01375 1.3e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
KLDDLPHA_01376 1.8e-67 S Glycosyltransferase like family
KLDDLPHA_01377 3.4e-76 rgpB GT2 M Glycosyl transferase family 2
KLDDLPHA_01378 3.9e-28 M biosynthesis protein
KLDDLPHA_01379 3.1e-90 cps3F
KLDDLPHA_01380 4.7e-76 M transferase activity, transferring glycosyl groups
KLDDLPHA_01381 3.2e-211 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
KLDDLPHA_01382 3.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
KLDDLPHA_01383 6.1e-25
KLDDLPHA_01384 2.1e-162 G Peptidase_C39 like family
KLDDLPHA_01385 0.0 2.7.7.6 M Peptidase family M23
KLDDLPHA_01386 2.1e-117 rfbP 2.7.8.6 M Bacterial sugar transferase
KLDDLPHA_01387 2.3e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KLDDLPHA_01388 1.9e-146 cps1D M Domain of unknown function (DUF4422)
KLDDLPHA_01389 1.2e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
KLDDLPHA_01390 4.9e-31
KLDDLPHA_01391 6.6e-34 S Protein of unknown function (DUF2922)
KLDDLPHA_01392 1.8e-143 yihY S Belongs to the UPF0761 family
KLDDLPHA_01393 3.4e-280 yjeM E Amino Acid
KLDDLPHA_01394 9.5e-256 E Arginine ornithine antiporter
KLDDLPHA_01395 1.6e-221 arcT 2.6.1.1 E Aminotransferase
KLDDLPHA_01396 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
KLDDLPHA_01397 1.4e-78 fld C Flavodoxin
KLDDLPHA_01398 1.3e-67 gtcA S Teichoic acid glycosylation protein
KLDDLPHA_01399 6.7e-21
KLDDLPHA_01400 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KLDDLPHA_01402 1.9e-231 yfmL L DEAD DEAH box helicase
KLDDLPHA_01403 5.9e-191 mocA S Oxidoreductase
KLDDLPHA_01404 9.1e-62 S Domain of unknown function (DUF4828)
KLDDLPHA_01405 1.1e-104 yvdD 3.2.2.10 S Belongs to the LOG family
KLDDLPHA_01406 1.5e-164 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KLDDLPHA_01407 2.2e-295 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KLDDLPHA_01408 3e-195 S Protein of unknown function (DUF3114)
KLDDLPHA_01409 5.5e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
KLDDLPHA_01410 1.1e-116 ybhL S Belongs to the BI1 family
KLDDLPHA_01411 1.1e-92 K Acetyltransferase (GNAT) family
KLDDLPHA_01412 6e-76 K LytTr DNA-binding domain
KLDDLPHA_01413 6.8e-67 S Protein of unknown function (DUF3021)
KLDDLPHA_01414 1.2e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KLDDLPHA_01415 2.4e-75 ogt 2.1.1.63 L Methyltransferase
KLDDLPHA_01416 2.6e-29 pnb C nitroreductase
KLDDLPHA_01417 1.4e-65 pnb C nitroreductase
KLDDLPHA_01418 1.7e-91
KLDDLPHA_01419 1.9e-83 yvbK 3.1.3.25 K GNAT family
KLDDLPHA_01420 6.8e-248 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
KLDDLPHA_01421 3.7e-205 amtB P ammonium transporter
KLDDLPHA_01422 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLDDLPHA_01423 9.8e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KLDDLPHA_01424 2.7e-185 I Alpha beta
KLDDLPHA_01425 6.5e-271 emrY EGP Major facilitator Superfamily
KLDDLPHA_01426 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
KLDDLPHA_01427 9.4e-253 yjjP S Putative threonine/serine exporter
KLDDLPHA_01428 1.1e-158 mleR K LysR family
KLDDLPHA_01429 3.8e-113 ydjP I Alpha/beta hydrolase family
KLDDLPHA_01430 3.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KLDDLPHA_01431 7.1e-273 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
KLDDLPHA_01432 3.6e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
KLDDLPHA_01433 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
KLDDLPHA_01434 1.7e-148 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KLDDLPHA_01435 6.1e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
KLDDLPHA_01436 1.4e-125 citR K sugar-binding domain protein
KLDDLPHA_01437 9.3e-203 P Sodium:sulfate symporter transmembrane region
KLDDLPHA_01438 3.5e-129 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLDDLPHA_01439 4.5e-266 frdC 1.3.5.4 C FAD binding domain
KLDDLPHA_01440 4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KLDDLPHA_01441 8.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KLDDLPHA_01442 4.3e-158 mleR K LysR family
KLDDLPHA_01443 6.6e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLDDLPHA_01444 9.6e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
KLDDLPHA_01445 7.7e-227 L PFAM plasmid pRiA4b ORF-3 family protein
KLDDLPHA_01446 7.8e-32 L PFAM plasmid pRiA4b ORF-3 family protein
KLDDLPHA_01448 1.1e-169 L transposase, IS605 OrfB family
KLDDLPHA_01449 1.3e-262 S Uncharacterized protein conserved in bacteria (DUF2252)
KLDDLPHA_01450 2.2e-21
KLDDLPHA_01451 2.3e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KLDDLPHA_01452 3.7e-73
KLDDLPHA_01453 6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLDDLPHA_01454 5.3e-131 ponA V Beta-lactamase enzyme family
KLDDLPHA_01455 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
KLDDLPHA_01456 1.3e-216 uhpT EGP Major facilitator Superfamily
KLDDLPHA_01457 4.3e-258 ytjP 3.5.1.18 E Dipeptidase
KLDDLPHA_01458 1.1e-124 arcD S C4-dicarboxylate anaerobic carrier
KLDDLPHA_01459 2e-135 L Transposase
KLDDLPHA_01460 1.1e-180 yfeX P Peroxidase
KLDDLPHA_01461 2.6e-91 lsa S ABC transporter
KLDDLPHA_01462 3.8e-114 lsa S ABC transporter
KLDDLPHA_01463 3e-133 I alpha/beta hydrolase fold
KLDDLPHA_01464 4e-179 MA20_14895 S Conserved hypothetical protein 698
KLDDLPHA_01465 8.4e-85 S NADPH-dependent FMN reductase
KLDDLPHA_01466 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KLDDLPHA_01467 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KLDDLPHA_01468 2e-231 mntH P H( )-stimulated, divalent metal cation uptake system
KLDDLPHA_01469 2.4e-79 Q Methyltransferase
KLDDLPHA_01470 7.7e-115 ktrA P domain protein
KLDDLPHA_01471 7.6e-239 ktrB P Potassium uptake protein
KLDDLPHA_01472 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KLDDLPHA_01473 1.4e-222 arcD U Amino acid permease
KLDDLPHA_01474 3.2e-259 E Arginine ornithine antiporter
KLDDLPHA_01475 2.7e-79 argR K Regulates arginine biosynthesis genes
KLDDLPHA_01476 3.1e-218 arcA 3.5.3.6 E Arginine
KLDDLPHA_01477 3.5e-183 ampC V Beta-lactamase
KLDDLPHA_01478 4.1e-19
KLDDLPHA_01479 6.6e-139 L Transposase
KLDDLPHA_01480 5e-158 M domain protein
KLDDLPHA_01481 1.9e-306 M domain protein
KLDDLPHA_01482 2e-91
KLDDLPHA_01484 3.3e-78 yjcE P Sodium proton antiporter
KLDDLPHA_01485 1.1e-149 yjcE P Sodium proton antiporter
KLDDLPHA_01486 2.3e-56
KLDDLPHA_01488 1.2e-85
KLDDLPHA_01489 0.0 copA 3.6.3.54 P P-type ATPase
KLDDLPHA_01490 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KLDDLPHA_01491 2.9e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KLDDLPHA_01492 4.5e-158 EG EamA-like transporter family
KLDDLPHA_01493 3.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
KLDDLPHA_01494 7.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KLDDLPHA_01495 3.6e-154 KT YcbB domain
KLDDLPHA_01496 3.1e-30 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KLDDLPHA_01498 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
KLDDLPHA_01499 9.6e-96 lacA 2.3.1.79 S Transferase hexapeptide repeat
KLDDLPHA_01500 4.1e-153 glcU U sugar transport
KLDDLPHA_01501 7.6e-272 yclK 2.7.13.3 T Histidine kinase
KLDDLPHA_01502 1.2e-134 K response regulator
KLDDLPHA_01504 1.3e-76 lytE M Lysin motif
KLDDLPHA_01505 1.8e-78 K Transcriptional regulator
KLDDLPHA_01506 0.0 oatA I Acyltransferase
KLDDLPHA_01507 5.6e-52
KLDDLPHA_01508 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KLDDLPHA_01509 8.5e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLDDLPHA_01510 1.3e-125 ybbR S YbbR-like protein
KLDDLPHA_01511 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KLDDLPHA_01512 3.7e-249 fucP G Major Facilitator Superfamily
KLDDLPHA_01513 5.1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KLDDLPHA_01514 6.1e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLDDLPHA_01515 3e-167 murB 1.3.1.98 M Cell wall formation
KLDDLPHA_01516 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
KLDDLPHA_01517 4.4e-76 S PAS domain
KLDDLPHA_01518 2.3e-87 K Acetyltransferase (GNAT) domain
KLDDLPHA_01519 2e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KLDDLPHA_01520 3.2e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KLDDLPHA_01521 9e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KLDDLPHA_01522 1.4e-104 yxjI
KLDDLPHA_01523 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KLDDLPHA_01524 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KLDDLPHA_01525 5.9e-143 est 3.1.1.1 S Serine aminopeptidase, S33
KLDDLPHA_01526 1.8e-34 secG U Preprotein translocase
KLDDLPHA_01527 3.1e-292 clcA P chloride
KLDDLPHA_01528 1.2e-244 yifK E Amino acid permease
KLDDLPHA_01529 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KLDDLPHA_01530 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLDDLPHA_01531 1.7e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KLDDLPHA_01532 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KLDDLPHA_01534 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KLDDLPHA_01535 8.8e-15
KLDDLPHA_01537 1.5e-169 whiA K May be required for sporulation
KLDDLPHA_01538 2.1e-185 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KLDDLPHA_01539 4.6e-160 rapZ S Displays ATPase and GTPase activities
KLDDLPHA_01540 1.6e-244 steT E amino acid
KLDDLPHA_01541 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KLDDLPHA_01542 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KLDDLPHA_01543 6.9e-14
KLDDLPHA_01544 1.9e-115 yfbR S HD containing hydrolase-like enzyme
KLDDLPHA_01545 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KLDDLPHA_01546 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
KLDDLPHA_01547 1.4e-161 aatB ET PFAM extracellular solute-binding protein, family 3
KLDDLPHA_01548 1.8e-204 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KLDDLPHA_01549 8.6e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KLDDLPHA_01550 7.8e-168 lutA C Cysteine-rich domain
KLDDLPHA_01551 3e-292 lutB C 4Fe-4S dicluster domain
KLDDLPHA_01552 1e-136 yrjD S LUD domain
KLDDLPHA_01553 9e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KLDDLPHA_01554 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KLDDLPHA_01555 3.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KLDDLPHA_01556 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KLDDLPHA_01557 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KLDDLPHA_01558 7.7e-31 KT PspC domain protein
KLDDLPHA_01559 1.1e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KLDDLPHA_01560 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KLDDLPHA_01561 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KLDDLPHA_01562 3.9e-114 comFC S Competence protein
KLDDLPHA_01563 1.6e-249 comFA L Helicase C-terminal domain protein
KLDDLPHA_01564 4.3e-107 yvyE 3.4.13.9 S YigZ family
KLDDLPHA_01565 1.3e-36 EGP Major facilitator Superfamily
KLDDLPHA_01566 6.1e-153 EGP Major facilitator Superfamily
KLDDLPHA_01567 6.2e-67 rmaI K Transcriptional regulator
KLDDLPHA_01568 2.7e-39
KLDDLPHA_01569 0.0 ydaO E amino acid
KLDDLPHA_01570 1.3e-301 ybeC E amino acid
KLDDLPHA_01571 1.3e-79 S Aminoacyl-tRNA editing domain
KLDDLPHA_01572 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KLDDLPHA_01573 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLDDLPHA_01575 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KLDDLPHA_01576 0.0 uup S ABC transporter, ATP-binding protein
KLDDLPHA_01577 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLDDLPHA_01578 1.3e-226 mtnE 2.6.1.83 E Aminotransferase
KLDDLPHA_01579 3.6e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KLDDLPHA_01580 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLDDLPHA_01581 3.8e-216 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KLDDLPHA_01582 8e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLDDLPHA_01583 2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KLDDLPHA_01584 2.9e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KLDDLPHA_01585 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KLDDLPHA_01586 6.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KLDDLPHA_01587 6.4e-171 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KLDDLPHA_01588 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KLDDLPHA_01589 7e-281 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KLDDLPHA_01590 3.8e-134 fat 3.1.2.21 I Acyl-ACP thioesterase
KLDDLPHA_01591 1.9e-153 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KLDDLPHA_01592 3.1e-43 yabA L Involved in initiation control of chromosome replication
KLDDLPHA_01593 2.5e-181 holB 2.7.7.7 L DNA polymerase III
KLDDLPHA_01594 2.9e-51 yaaQ S Cyclic-di-AMP receptor
KLDDLPHA_01595 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLDDLPHA_01596 2.8e-38 S Protein of unknown function (DUF2508)
KLDDLPHA_01597 6.3e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KLDDLPHA_01598 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KLDDLPHA_01599 7.1e-304 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLDDLPHA_01600 1e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KLDDLPHA_01601 3.4e-35 nrdH O Glutaredoxin
KLDDLPHA_01602 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLDDLPHA_01603 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLDDLPHA_01604 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KLDDLPHA_01605 1.3e-131 S Putative adhesin
KLDDLPHA_01606 3.2e-83 XK27_06920 S Protein of unknown function (DUF1700)
KLDDLPHA_01607 2.4e-56 K transcriptional regulator PadR family
KLDDLPHA_01608 3.2e-38 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KLDDLPHA_01610 3.4e-48
KLDDLPHA_01611 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KLDDLPHA_01612 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KLDDLPHA_01613 4.4e-166 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KLDDLPHA_01614 8e-224 aadAT EK Aminotransferase, class I
KLDDLPHA_01615 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KLDDLPHA_01616 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KLDDLPHA_01617 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
KLDDLPHA_01618 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KLDDLPHA_01619 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KLDDLPHA_01620 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLDDLPHA_01621 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KLDDLPHA_01622 3.8e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLDDLPHA_01623 1.1e-204 yacL S domain protein
KLDDLPHA_01624 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLDDLPHA_01625 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KLDDLPHA_01626 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
KLDDLPHA_01627 2.2e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KLDDLPHA_01628 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
KLDDLPHA_01629 6.2e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KLDDLPHA_01630 2.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLDDLPHA_01631 1.1e-119 tcyB E ABC transporter
KLDDLPHA_01632 2.5e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KLDDLPHA_01633 1.3e-167 I alpha/beta hydrolase fold
KLDDLPHA_01634 1e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLDDLPHA_01635 0.0 S Bacterial membrane protein, YfhO
KLDDLPHA_01636 1.7e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KLDDLPHA_01637 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KLDDLPHA_01639 2.9e-81 ydcK S Belongs to the SprT family
KLDDLPHA_01640 0.0 yhgF K Tex-like protein N-terminal domain protein
KLDDLPHA_01641 2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KLDDLPHA_01642 3.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLDDLPHA_01643 5.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
KLDDLPHA_01644 2.2e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KLDDLPHA_01645 1e-301 aspT P Predicted Permease Membrane Region
KLDDLPHA_01646 8.5e-249 EGP Major facilitator Superfamily
KLDDLPHA_01647 8.5e-111
KLDDLPHA_01650 5.9e-149 yjjH S Calcineurin-like phosphoesterase
KLDDLPHA_01651 1.3e-263 dtpT U amino acid peptide transporter
KLDDLPHA_01656 2.6e-122 L Integrase core domain
KLDDLPHA_01657 1.4e-109 L Bacterial dnaA protein
KLDDLPHA_01658 1.2e-123 S Alpha beta hydrolase
KLDDLPHA_01659 3.3e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLDDLPHA_01660 1.3e-97
KLDDLPHA_01662 1.3e-122 yciB M ErfK YbiS YcfS YnhG
KLDDLPHA_01663 1.2e-260 S Putative peptidoglycan binding domain
KLDDLPHA_01664 3.9e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
KLDDLPHA_01665 1.6e-67
KLDDLPHA_01666 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
KLDDLPHA_01667 8.9e-215 yttB EGP Major facilitator Superfamily
KLDDLPHA_01668 2.6e-101
KLDDLPHA_01669 1e-24
KLDDLPHA_01670 2.5e-172 scrR K Transcriptional regulator, LacI family
KLDDLPHA_01671 2.9e-235 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLDDLPHA_01672 9.2e-50 czrA K Transcriptional regulator, ArsR family
KLDDLPHA_01673 2.5e-36
KLDDLPHA_01674 0.0 yhcA V ABC transporter, ATP-binding protein
KLDDLPHA_01675 5e-117 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KLDDLPHA_01676 4e-166 hrtB V ABC transporter permease
KLDDLPHA_01677 1.8e-84 ygfC K transcriptional regulator (TetR family)
KLDDLPHA_01678 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
KLDDLPHA_01679 8.9e-287 mntH P H( )-stimulated, divalent metal cation uptake system
KLDDLPHA_01680 6.4e-32
KLDDLPHA_01681 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLDDLPHA_01683 6e-214 yxiO S Vacuole effluxer Atg22 like
KLDDLPHA_01684 6.3e-52 npp S type I phosphodiesterase nucleotide pyrophosphatase
KLDDLPHA_01685 1.1e-130 npp S type I phosphodiesterase nucleotide pyrophosphatase
KLDDLPHA_01686 5.1e-238 E amino acid
KLDDLPHA_01687 8.6e-119 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLDDLPHA_01688 2.8e-15 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLDDLPHA_01689 9.6e-74 elaA S Gnat family
KLDDLPHA_01690 1.2e-120 GM NmrA-like family
KLDDLPHA_01691 1.8e-50 hxlR K Transcriptional regulator, HxlR family
KLDDLPHA_01692 4.1e-107 XK27_02070 S Nitroreductase family
KLDDLPHA_01693 1.2e-82 K Transcriptional regulator, HxlR family
KLDDLPHA_01694 1.6e-233
KLDDLPHA_01695 1.4e-209 EGP Major facilitator Superfamily
KLDDLPHA_01696 3e-256 pepC 3.4.22.40 E aminopeptidase
KLDDLPHA_01697 6e-109 ylbE GM NAD dependent epimerase dehydratase family protein
KLDDLPHA_01698 0.0 pepN 3.4.11.2 E aminopeptidase
KLDDLPHA_01699 1.9e-48 K Transcriptional regulator
KLDDLPHA_01700 2.3e-24 folT S ECF transporter, substrate-specific component
KLDDLPHA_01701 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
KLDDLPHA_01702 5.1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KLDDLPHA_01703 3.7e-26 L PFAM Integrase catalytic region
KLDDLPHA_01704 2.1e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
KLDDLPHA_01705 1.9e-59 yneR
KLDDLPHA_01706 1.6e-101 qorB 1.6.5.2 GM NmrA-like family
KLDDLPHA_01707 3.4e-152 akr5f 1.1.1.346 S reductase
KLDDLPHA_01708 2.1e-144 K Transcriptional regulator
KLDDLPHA_01709 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
KLDDLPHA_01710 2.3e-155 ypuA S Protein of unknown function (DUF1002)
KLDDLPHA_01711 6.6e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KLDDLPHA_01712 5.1e-153 tesE Q hydratase
KLDDLPHA_01713 2.2e-119 S Alpha beta hydrolase
KLDDLPHA_01714 1.5e-65 lacA S transferase hexapeptide repeat
KLDDLPHA_01715 8.7e-82 S Peptidase propeptide and YPEB domain
KLDDLPHA_01716 1.3e-214 T GHKL domain
KLDDLPHA_01717 1.6e-109 T Transcriptional regulatory protein, C terminal
KLDDLPHA_01718 5.9e-18 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
KLDDLPHA_01720 4.8e-193 V Beta-lactamase
KLDDLPHA_01721 2.7e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLDDLPHA_01722 7e-104 yhiD S MgtC family
KLDDLPHA_01723 7.3e-13 S GyrI-like small molecule binding domain
KLDDLPHA_01725 9.5e-113 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KLDDLPHA_01726 3.2e-50 azlD E Branched-chain amino acid transport
KLDDLPHA_01727 4.4e-59 azlC E azaleucine resistance protein AzlC
KLDDLPHA_01728 1.3e-84 L PFAM transposase IS200-family protein
KLDDLPHA_01729 2.2e-48 azlC E azaleucine resistance protein AzlC
KLDDLPHA_01730 3.2e-259 K Aminotransferase class I and II
KLDDLPHA_01731 1.9e-27 S amidohydrolase
KLDDLPHA_01732 2.8e-50 S amidohydrolase
KLDDLPHA_01733 1.5e-91 2.3.1.183 M Acetyltransferase GNAT family
KLDDLPHA_01734 2.2e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KLDDLPHA_01735 3.2e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
KLDDLPHA_01736 5.8e-291 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KLDDLPHA_01737 0.0 asnB 6.3.5.4 E Asparagine synthase
KLDDLPHA_01738 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KLDDLPHA_01739 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KLDDLPHA_01740 6.3e-129 jag S R3H domain protein
KLDDLPHA_01741 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLDDLPHA_01742 6e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KLDDLPHA_01743 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KLDDLPHA_01744 5.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KLDDLPHA_01745 2e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KLDDLPHA_01746 3.8e-34 yaaA S S4 domain protein YaaA
KLDDLPHA_01747 6.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KLDDLPHA_01748 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLDDLPHA_01749 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLDDLPHA_01750 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KLDDLPHA_01751 2.8e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLDDLPHA_01752 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KLDDLPHA_01753 2.4e-74 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KLDDLPHA_01754 2.6e-100 deoR K sugar-binding domain protein
KLDDLPHA_01755 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KLDDLPHA_01756 2e-74 rplI J Binds to the 23S rRNA
KLDDLPHA_01757 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KLDDLPHA_01758 9e-207 yttB EGP Major facilitator Superfamily
KLDDLPHA_01759 9.1e-61
KLDDLPHA_01760 6.9e-156 S Polyphosphate nucleotide phosphotransferase, PPK2 family
KLDDLPHA_01762 7.5e-96 Z012_01130 S Fic/DOC family
KLDDLPHA_01764 6.8e-72 K helix_turn_helix multiple antibiotic resistance protein
KLDDLPHA_01765 7.6e-308 lmrA 3.6.3.44 V ABC transporter
KLDDLPHA_01767 3.1e-130 K response regulator
KLDDLPHA_01768 0.0 vicK 2.7.13.3 T Histidine kinase
KLDDLPHA_01769 2.4e-245 yycH S YycH protein
KLDDLPHA_01770 7.8e-149 yycI S YycH protein
KLDDLPHA_01771 2.3e-153 vicX 3.1.26.11 S domain protein
KLDDLPHA_01772 1.6e-214 htrA 3.4.21.107 O serine protease
KLDDLPHA_01773 2.3e-84 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
KLDDLPHA_01774 6.5e-179 ABC-SBP S ABC transporter
KLDDLPHA_01775 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KLDDLPHA_01777 2.9e-96 S reductase
KLDDLPHA_01778 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
KLDDLPHA_01779 5e-75 osmC O OsmC-like protein
KLDDLPHA_01780 3.2e-173 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLDDLPHA_01781 1.2e-214 patA 2.6.1.1 E Aminotransferase
KLDDLPHA_01782 7.8e-32
KLDDLPHA_01783 0.0 clpL O associated with various cellular activities
KLDDLPHA_01785 2e-103 wecD3 K PFAM GCN5-related N-acetyltransferase
KLDDLPHA_01786 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLDDLPHA_01787 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KLDDLPHA_01788 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KLDDLPHA_01789 4.3e-172 malR K Transcriptional regulator, LacI family
KLDDLPHA_01790 5.7e-214 phbA 2.3.1.9 I Belongs to the thiolase family
KLDDLPHA_01791 1.1e-256 malT G Major Facilitator
KLDDLPHA_01792 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KLDDLPHA_01793 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KLDDLPHA_01794 1e-71
KLDDLPHA_01795 3.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
KLDDLPHA_01796 3.3e-118 K response regulator
KLDDLPHA_01797 3.1e-226 sptS 2.7.13.3 T Histidine kinase
KLDDLPHA_01798 1.6e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KLDDLPHA_01799 6.6e-136 puuD S peptidase C26
KLDDLPHA_01800 5.9e-168 yvgN C Aldo keto reductase
KLDDLPHA_01801 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
KLDDLPHA_01802 3e-87 hmpT S ECF-type riboflavin transporter, S component
KLDDLPHA_01803 1.7e-262 nox C NADH oxidase
KLDDLPHA_01804 9.9e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLDDLPHA_01805 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KLDDLPHA_01806 6.9e-83
KLDDLPHA_01807 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KLDDLPHA_01809 1.4e-13 steT_1 E amino acid
KLDDLPHA_01810 2.1e-12 K Transcriptional regulator, TetR family
KLDDLPHA_01811 3.4e-74 K Transcriptional regulator, TetR family
KLDDLPHA_01812 8.3e-72
KLDDLPHA_01813 9.9e-267 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
KLDDLPHA_01814 1.2e-269 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
KLDDLPHA_01815 3.9e-280 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
KLDDLPHA_01816 1.3e-124 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KLDDLPHA_01817 2.9e-184 G Major Facilitator
KLDDLPHA_01818 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KLDDLPHA_01819 3.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KLDDLPHA_01820 6.1e-260 G Major Facilitator
KLDDLPHA_01821 3.8e-174 K Transcriptional regulator, LacI family
KLDDLPHA_01822 1.7e-265 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLDDLPHA_01824 2.4e-101 nqr 1.5.1.36 S reductase
KLDDLPHA_01825 2.2e-203 XK27_09615 S reductase
KLDDLPHA_01826 3.7e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KLDDLPHA_01827 1.9e-43 L Transposase
KLDDLPHA_01828 3.6e-249 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KLDDLPHA_01829 2.2e-263 glnP P ABC transporter
KLDDLPHA_01830 1.9e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLDDLPHA_01831 1.6e-220 cycA E Amino acid permease
KLDDLPHA_01832 1.3e-218 nupG F Nucleoside transporter
KLDDLPHA_01833 6.6e-170 rihC 3.2.2.1 F Nucleoside
KLDDLPHA_01834 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
KLDDLPHA_01835 3.7e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KLDDLPHA_01836 1.5e-143 noc K Belongs to the ParB family
KLDDLPHA_01837 3.6e-140 soj D Sporulation initiation inhibitor
KLDDLPHA_01838 5e-154 spo0J K Belongs to the ParB family
KLDDLPHA_01839 1.2e-31 yyzM S Bacterial protein of unknown function (DUF951)
KLDDLPHA_01840 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KLDDLPHA_01841 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
KLDDLPHA_01842 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KLDDLPHA_01843 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KLDDLPHA_01844 3.2e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
KLDDLPHA_01845 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KLDDLPHA_01846 4e-170 deoR K sugar-binding domain protein
KLDDLPHA_01847 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLDDLPHA_01848 3.8e-125 K response regulator
KLDDLPHA_01849 2.4e-201 hpk31 2.7.13.3 T Histidine kinase
KLDDLPHA_01850 2.7e-139 azlC E AzlC protein
KLDDLPHA_01851 1.6e-52 azlD S branched-chain amino acid
KLDDLPHA_01852 5.3e-132 K LysR substrate binding domain
KLDDLPHA_01853 1.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KLDDLPHA_01854 7.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KLDDLPHA_01855 1.9e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KLDDLPHA_01856 5.1e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KLDDLPHA_01857 9.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLDDLPHA_01858 1.4e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
KLDDLPHA_01859 1e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KLDDLPHA_01860 1.2e-227 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KLDDLPHA_01861 6.6e-174 K AI-2E family transporter
KLDDLPHA_01862 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KLDDLPHA_01863 8.4e-207 gldA 1.1.1.6 C dehydrogenase
KLDDLPHA_01864 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KLDDLPHA_01865 1.3e-38
KLDDLPHA_01866 4e-124 pgm3 3.1.3.73 G phosphoglycerate mutase family
KLDDLPHA_01867 4.6e-36 K Bacterial transcriptional regulator
KLDDLPHA_01869 1.9e-45 IQ Dehydrogenase reductase
KLDDLPHA_01870 2e-161 S C4-dicarboxylate anaerobic carrier
KLDDLPHA_01871 4e-102 S C4-dicarboxylate anaerobic carrier
KLDDLPHA_01872 1.6e-241 pbuX F xanthine permease
KLDDLPHA_01873 2.3e-278 pipD E Dipeptidase
KLDDLPHA_01874 2.8e-168 corA P CorA-like Mg2+ transporter protein
KLDDLPHA_01875 3.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLDDLPHA_01876 6.6e-131 terC P membrane
KLDDLPHA_01877 1.9e-55 trxA O Belongs to the thioredoxin family
KLDDLPHA_01878 2.7e-236 mepA V MATE efflux family protein
KLDDLPHA_01879 4.9e-54 K Transcriptional regulator, ArsR family
KLDDLPHA_01880 7.4e-95 P Cadmium resistance transporter
KLDDLPHA_01881 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
KLDDLPHA_01882 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KLDDLPHA_01883 4.1e-181 ABC-SBP S ABC transporter
KLDDLPHA_01884 1.7e-73 M PFAM NLP P60 protein
KLDDLPHA_01885 6e-98 S Protein of unknown function (DUF3278)
KLDDLPHA_01886 1e-28 WQ51_00220 K Helix-turn-helix domain
KLDDLPHA_01887 4.5e-51 L Integrase
KLDDLPHA_01888 1.1e-13 K Transcriptional
KLDDLPHA_01889 8.2e-72 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLDDLPHA_01890 6.6e-182 arsB 1.20.4.1 P Sodium Bile acid symporter family
KLDDLPHA_01891 6.4e-08 S HTH domain
KLDDLPHA_01892 7.1e-273 S ABC transporter, ATP-binding protein
KLDDLPHA_01893 5e-142 S Putative ABC-transporter type IV
KLDDLPHA_01894 1.1e-104 NU mannosyl-glycoprotein
KLDDLPHA_01895 1.2e-247 brnQ U Component of the transport system for branched-chain amino acids
KLDDLPHA_01896 6.2e-227 S Uncharacterized protein conserved in bacteria (DUF2325)
KLDDLPHA_01897 3.4e-205 nrnB S DHHA1 domain
KLDDLPHA_01898 9.1e-49
KLDDLPHA_01899 5.5e-29 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLDDLPHA_01900 5.3e-16 S Domain of unknown function (DUF4767)
KLDDLPHA_01901 1.5e-52
KLDDLPHA_01902 1.5e-118 yrkL S Flavodoxin-like fold
KLDDLPHA_01904 5.9e-64 yeaO S Protein of unknown function, DUF488
KLDDLPHA_01905 5.2e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KLDDLPHA_01906 4.4e-203 3.1.3.1 S associated with various cellular activities
KLDDLPHA_01907 9.6e-231 S Putative metallopeptidase domain
KLDDLPHA_01908 1.9e-46
KLDDLPHA_01909 0.0 pepO 3.4.24.71 O Peptidase family M13
KLDDLPHA_01910 1.4e-105 K Helix-turn-helix XRE-family like proteins
KLDDLPHA_01911 3.9e-87 ymdB S Macro domain protein
KLDDLPHA_01912 3.8e-194 EGP Major facilitator Superfamily
KLDDLPHA_01913 2.3e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLDDLPHA_01914 8e-54 K helix_turn_helix, mercury resistance
KLDDLPHA_01915 4.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KLDDLPHA_01916 5.9e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KLDDLPHA_01917 0.0 ysaB V FtsX-like permease family
KLDDLPHA_01918 4.9e-134 macB2 V ABC transporter, ATP-binding protein
KLDDLPHA_01919 2.8e-182 T PhoQ Sensor
KLDDLPHA_01920 2e-132 K response regulator
KLDDLPHA_01921 3.9e-156 ytbE 1.1.1.346 S Aldo keto reductase
KLDDLPHA_01922 2.9e-134 pnuC H nicotinamide mononucleotide transporter
KLDDLPHA_01923 1.2e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLDDLPHA_01924 5.3e-201
KLDDLPHA_01925 2e-52
KLDDLPHA_01926 9.1e-36
KLDDLPHA_01927 1.5e-91 yxkA S Phosphatidylethanolamine-binding protein
KLDDLPHA_01928 1.9e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
KLDDLPHA_01929 4.1e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
KLDDLPHA_01930 2.5e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KLDDLPHA_01931 3.1e-278 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KLDDLPHA_01932 5.4e-181 galR K Transcriptional regulator
KLDDLPHA_01933 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KLDDLPHA_01934 1.4e-78 K AsnC family
KLDDLPHA_01935 1.6e-79 uspA T universal stress protein
KLDDLPHA_01936 6.8e-44 ltrA S Bacterial low temperature requirement A protein (LtrA)
KLDDLPHA_01937 1.8e-65 ltrA S Bacterial low temperature requirement A protein (LtrA)
KLDDLPHA_01938 0.0 lacS G Transporter
KLDDLPHA_01939 2.3e-28
KLDDLPHA_01940 7.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KLDDLPHA_01941 8.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KLDDLPHA_01942 4.4e-190 yeaN P Transporter, major facilitator family protein
KLDDLPHA_01943 2.7e-73 S 3-demethylubiquinone-9 3-methyltransferase
KLDDLPHA_01944 2.7e-82 nrdI F Belongs to the NrdI family
KLDDLPHA_01945 1.6e-236 yhdP S Transporter associated domain
KLDDLPHA_01946 1.4e-153 ypdB V (ABC) transporter
KLDDLPHA_01947 2.5e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
KLDDLPHA_01948 1.1e-89 M1-874 K Domain of unknown function (DUF1836)
KLDDLPHA_01949 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
KLDDLPHA_01950 5.7e-132 XK27_07210 6.1.1.6 S B3 4 domain
KLDDLPHA_01951 2.6e-160 S AI-2E family transporter
KLDDLPHA_01952 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
KLDDLPHA_01953 2.2e-160
KLDDLPHA_01954 1e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KLDDLPHA_01955 3.6e-138 eutJ E Hsp70 protein
KLDDLPHA_01956 8.3e-159 K helix_turn_helix, arabinose operon control protein
KLDDLPHA_01957 1.6e-37 pduA_4 CQ BMC
KLDDLPHA_01958 2.7e-134 pduB E BMC
KLDDLPHA_01959 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
KLDDLPHA_01960 3.9e-125 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
KLDDLPHA_01961 2.4e-71 pduE 4.2.1.28 Q Dehydratase small subunit
KLDDLPHA_01962 9.6e-309 pduG D Diol dehydratase reactivase ATPase-like domain
KLDDLPHA_01963 2.6e-45 pduH S Dehydratase medium subunit
KLDDLPHA_01964 1.8e-56 pduK CQ BMC
KLDDLPHA_01965 7.8e-40 pduA_4 CQ BMC
KLDDLPHA_01966 1.9e-115 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
KLDDLPHA_01967 1.3e-79 S Putative propanediol utilisation
KLDDLPHA_01968 5.2e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
KLDDLPHA_01969 2.2e-102 pduO 2.5.1.17 S Cobalamin adenosyltransferase
KLDDLPHA_01970 4.5e-77 pduO S Haem-degrading
KLDDLPHA_01971 3.1e-262 pduP 1.2.1.87 C Aldehyde dehydrogenase family
KLDDLPHA_01972 2.1e-202 pduQ C Iron-containing alcohol dehydrogenase
KLDDLPHA_01973 1.9e-217 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLDDLPHA_01974 1.1e-53 pduU E BMC
KLDDLPHA_01975 1.1e-115 3.1.3.48 T Pfam:Y_phosphatase3C
KLDDLPHA_01976 1.9e-75 pgm1 3.1.3.73 G phosphoglycerate mutase
KLDDLPHA_01977 5.9e-68 P Cadmium resistance transporter
KLDDLPHA_01978 2.6e-68 eutP E Ethanolamine utilisation - propanediol utilisation
KLDDLPHA_01979 2.2e-73 fld C Flavodoxin
KLDDLPHA_01980 2.7e-117 XK27_04590 S NADPH-dependent FMN reductase
KLDDLPHA_01981 3.2e-77 cobO 2.5.1.17 S Cobalamin adenosyltransferase
KLDDLPHA_01982 1.8e-169 cobD 4.1.1.81 E Aminotransferase class I and II
KLDDLPHA_01983 8.1e-204 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
KLDDLPHA_01984 4.9e-147 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KLDDLPHA_01985 2.5e-108 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
KLDDLPHA_01986 6.4e-186 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KLDDLPHA_01987 1.6e-79 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KLDDLPHA_01988 1.4e-77 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
KLDDLPHA_01989 8.1e-129 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KLDDLPHA_01990 3.3e-144 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
KLDDLPHA_01991 1.1e-127 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KLDDLPHA_01992 2.5e-98 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
KLDDLPHA_01993 4.6e-178 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KLDDLPHA_01994 1.8e-107 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
KLDDLPHA_01995 8.1e-91 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KLDDLPHA_01996 1e-123 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
KLDDLPHA_01997 7.6e-44 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
KLDDLPHA_01998 6.8e-103 cbiQ P Cobalt transport protein
KLDDLPHA_01999 7.8e-122 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
KLDDLPHA_02000 2.7e-240 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
KLDDLPHA_02001 7e-59 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
KLDDLPHA_02002 4.1e-194 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KLDDLPHA_02003 2.6e-137 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KLDDLPHA_02004 2.8e-174 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
KLDDLPHA_02005 3.9e-240 hemL 5.4.3.8 H Aminotransferase class-III
KLDDLPHA_02006 1.6e-76 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
KLDDLPHA_02007 4.9e-118 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KLDDLPHA_02008 5.8e-74 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
KLDDLPHA_02009 6.5e-64 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KLDDLPHA_02010 2e-146 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
KLDDLPHA_02011 1.4e-14 cnrT EG EamA-like transporter family
KLDDLPHA_02012 5.2e-17 cnrT EG PFAM EamA-like transporter family
KLDDLPHA_02013 9.8e-51 S Domain of unknown function (DUF4430)
KLDDLPHA_02014 5.9e-73 S ECF transporter, substrate-specific component
KLDDLPHA_02015 8.3e-19 S PFAM Archaeal ATPase
KLDDLPHA_02017 1.6e-178 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLDDLPHA_02018 1.7e-17 K Winged helix DNA-binding domain
KLDDLPHA_02019 2.9e-299 lmrA V ABC transporter, ATP-binding protein
KLDDLPHA_02020 0.0 yfiC V ABC transporter
KLDDLPHA_02021 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
KLDDLPHA_02022 5.8e-269 pipD E Dipeptidase
KLDDLPHA_02023 1.6e-85 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KLDDLPHA_02024 4.7e-126 gntR K UbiC transcription regulator-associated domain protein
KLDDLPHA_02025 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KLDDLPHA_02026 3.6e-236 yagE E amino acid
KLDDLPHA_02027 1.2e-137 aroD S Serine hydrolase (FSH1)
KLDDLPHA_02028 2.9e-165 GK ROK family
KLDDLPHA_02029 0.0 tetP J elongation factor G
KLDDLPHA_02030 5.1e-81 uspA T universal stress protein
KLDDLPHA_02031 6.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
KLDDLPHA_02032 7.1e-63
KLDDLPHA_02033 4e-14
KLDDLPHA_02034 5.8e-59
KLDDLPHA_02035 1.8e-38
KLDDLPHA_02036 1.1e-134 V ABC transporter
KLDDLPHA_02037 2.6e-211 EGP Major facilitator Superfamily
KLDDLPHA_02038 7.2e-256 G PTS system Galactitol-specific IIC component
KLDDLPHA_02039 9.8e-23 1.6.5.5 C Zinc-binding dehydrogenase
KLDDLPHA_02040 2e-86 1.6.5.5 C Zinc-binding dehydrogenase
KLDDLPHA_02041 1e-159
KLDDLPHA_02042 1e-72 K Transcriptional regulator
KLDDLPHA_02043 2e-172 D Alpha beta
KLDDLPHA_02044 6.4e-52 ypaA S Protein of unknown function (DUF1304)
KLDDLPHA_02045 0.0 yjcE P Sodium proton antiporter
KLDDLPHA_02046 1.6e-52 yvlA
KLDDLPHA_02047 6.6e-111 P Cobalt transport protein
KLDDLPHA_02048 4.9e-249 cbiO1 S ABC transporter, ATP-binding protein
KLDDLPHA_02049 1.3e-96 S ABC-type cobalt transport system, permease component
KLDDLPHA_02050 9.6e-133 S membrane transporter protein
KLDDLPHA_02051 2.6e-09 S membrane transporter protein
KLDDLPHA_02052 1.2e-112 IQ KR domain
KLDDLPHA_02053 2e-09 IQ KR domain
KLDDLPHA_02054 8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
KLDDLPHA_02055 1.1e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KLDDLPHA_02056 2.3e-28 S Double zinc ribbon
KLDDLPHA_02057 3.7e-59 S Double zinc ribbon
KLDDLPHA_02058 4.6e-35 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLDDLPHA_02059 2e-95 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLDDLPHA_02060 1.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
KLDDLPHA_02061 4.8e-177 yagE E amino acid
KLDDLPHA_02062 6.2e-45 yagE E amino acid
KLDDLPHA_02063 9.9e-85 dps P Belongs to the Dps family
KLDDLPHA_02064 0.0 pacL 3.6.3.8 P P-type ATPase
KLDDLPHA_02065 6.7e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KLDDLPHA_02066 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KLDDLPHA_02067 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KLDDLPHA_02068 3.9e-145 potB P ABC transporter permease
KLDDLPHA_02069 6.5e-140 potC P ABC transporter permease
KLDDLPHA_02070 1.8e-206 potD P ABC transporter
KLDDLPHA_02071 7.9e-34
KLDDLPHA_02072 3.6e-65
KLDDLPHA_02073 9.5e-18
KLDDLPHA_02074 2.3e-31

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)