ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMBAKEGM_00001 2.6e-71 G Major Facilitator Superfamily
HMBAKEGM_00003 3.1e-77 L Probable transposase
HMBAKEGM_00004 2.1e-99 S Uncharacterised protein family (UPF0236)
HMBAKEGM_00005 6.6e-107 S Uncharacterised protein family (UPF0236)
HMBAKEGM_00009 1.1e-71 L IS1381, transposase OrfA
HMBAKEGM_00020 1.3e-108 L An automated process has identified a potential problem with this gene model
HMBAKEGM_00021 3.5e-27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMBAKEGM_00022 1.1e-95 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMBAKEGM_00023 6.3e-193 L COG2826 Transposase and inactivated derivatives, IS30 family
HMBAKEGM_00025 9.8e-118 KLT serine threonine protein kinase
HMBAKEGM_00026 6.3e-08 L COG2963 Transposase and inactivated derivatives
HMBAKEGM_00027 1.9e-45 L COG2963 Transposase and inactivated derivatives
HMBAKEGM_00028 7.3e-269 L COG2963 Transposase and inactivated derivatives
HMBAKEGM_00029 3.8e-248 L Transposase
HMBAKEGM_00030 5.9e-106 L Resolvase, N terminal domain
HMBAKEGM_00031 1.8e-18
HMBAKEGM_00032 2.5e-64 XK27_01125 L IS66 Orf2 like protein
HMBAKEGM_00033 5.8e-32 S Transposase C of IS166 homeodomain
HMBAKEGM_00034 1.4e-261 L Transposase IS66 family
HMBAKEGM_00036 2.4e-83 S COG NOG38524 non supervised orthologous group
HMBAKEGM_00037 1.8e-18 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HMBAKEGM_00038 2.3e-29 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HMBAKEGM_00039 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMBAKEGM_00040 4.2e-33 ykzG S Belongs to the UPF0356 family
HMBAKEGM_00041 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMBAKEGM_00042 0.0 typA T GTP-binding protein TypA
HMBAKEGM_00043 4.7e-208 ftsW D Belongs to the SEDS family
HMBAKEGM_00044 8.7e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HMBAKEGM_00045 2.2e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HMBAKEGM_00046 2.7e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMBAKEGM_00047 1.2e-191 ylbL T Belongs to the peptidase S16 family
HMBAKEGM_00048 6.2e-83 comEA L Competence protein ComEA
HMBAKEGM_00049 0.0 comEC S Competence protein ComEC
HMBAKEGM_00050 4.8e-174 holA 2.7.7.7 L DNA polymerase III delta subunit
HMBAKEGM_00051 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
HMBAKEGM_00052 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMBAKEGM_00053 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMBAKEGM_00054 2.2e-151
HMBAKEGM_00055 3.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMBAKEGM_00056 6.4e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMBAKEGM_00057 1.3e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMBAKEGM_00058 7.5e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HMBAKEGM_00059 1.5e-19 yjeM E Amino Acid
HMBAKEGM_00060 6e-14 yjeM E Amino Acid
HMBAKEGM_00061 2.1e-191 yjeM E Amino Acid
HMBAKEGM_00062 1.5e-191 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMBAKEGM_00063 3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMBAKEGM_00064 7e-220 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMBAKEGM_00065 3.3e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HMBAKEGM_00066 9.8e-18 IQ reductase
HMBAKEGM_00067 7.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMBAKEGM_00068 9.3e-74 nrdI F Probably involved in ribonucleotide reductase function
HMBAKEGM_00069 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMBAKEGM_00078 4.8e-221 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HMBAKEGM_00079 6.4e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
HMBAKEGM_00080 3.7e-177 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMBAKEGM_00081 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMBAKEGM_00082 2.3e-29 secG U Preprotein translocase
HMBAKEGM_00083 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMBAKEGM_00084 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMBAKEGM_00087 1.1e-57
HMBAKEGM_00088 4.3e-16
HMBAKEGM_00089 1.3e-14
HMBAKEGM_00091 4.3e-110 S Plasmid replication protein
HMBAKEGM_00093 2.1e-21
HMBAKEGM_00094 0.0 oppA E ABC transporter substrate-binding protein
HMBAKEGM_00096 4.4e-94 S SLAP domain
HMBAKEGM_00097 2.5e-48 S SLAP domain
HMBAKEGM_00098 5.1e-20 XK27_01125 L IS66 Orf2 like protein
HMBAKEGM_00099 4.2e-66 G Major Facilitator Superfamily
HMBAKEGM_00100 1.7e-114 papP P ABC transporter, permease protein
HMBAKEGM_00101 3.3e-89 P ABC transporter permease
HMBAKEGM_00102 3.9e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMBAKEGM_00103 3.7e-162 cjaA ET ABC transporter substrate-binding protein
HMBAKEGM_00104 8.6e-26 L metal-sulfur cluster biosynthetic enzyme
HMBAKEGM_00105 6e-21 S Cysteine-rich secretory protein family
HMBAKEGM_00106 6.8e-66 S Cysteine-rich secretory protein family
HMBAKEGM_00107 2.3e-10
HMBAKEGM_00108 3e-15
HMBAKEGM_00110 1.5e-44 S membrane transporter protein
HMBAKEGM_00111 1.8e-201 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HMBAKEGM_00112 3.9e-133 S cellulase activity
HMBAKEGM_00113 1.5e-75 L PFAM Integrase catalytic region
HMBAKEGM_00114 6.5e-102 tnpR L Resolvase, N terminal domain
HMBAKEGM_00115 1.8e-87 L Psort location Cytoplasmic, score
HMBAKEGM_00117 3.9e-25 L Psort location Cytoplasmic, score
HMBAKEGM_00121 2.5e-43 repA S Replication initiator protein A
HMBAKEGM_00123 4.6e-80 ropB K Transcriptional regulator
HMBAKEGM_00124 3.8e-50
HMBAKEGM_00125 4.5e-71 tnp2PF3 L manually curated
HMBAKEGM_00126 7e-104 L Integrase
HMBAKEGM_00127 1.7e-38 S Antitoxin component of a toxin-antitoxin (TA) module
HMBAKEGM_00128 1.8e-50 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HMBAKEGM_00129 2.7e-96
HMBAKEGM_00130 1.3e-47
HMBAKEGM_00131 6.9e-41
HMBAKEGM_00132 1.7e-267 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HMBAKEGM_00133 6.1e-132 glvR K Helix-turn-helix domain, rpiR family
HMBAKEGM_00134 1.7e-187 ansA 3.5.1.1 EJ L-asparaginase, type I
HMBAKEGM_00135 3.2e-15
HMBAKEGM_00136 7.4e-18
HMBAKEGM_00137 3.6e-98 3.6.3.8 P P-type ATPase
HMBAKEGM_00138 2.3e-117 3.6.3.8 P P-type ATPase
HMBAKEGM_00139 8.2e-125
HMBAKEGM_00140 2.1e-238 S response to antibiotic
HMBAKEGM_00141 3.7e-134 cysA V ABC transporter, ATP-binding protein
HMBAKEGM_00142 0.0 V FtsX-like permease family
HMBAKEGM_00143 2.2e-165 aspT P Predicted Permease Membrane Region
HMBAKEGM_00144 2.6e-86 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HMBAKEGM_00145 1.1e-126 pgm3 G Phosphoglycerate mutase family
HMBAKEGM_00146 9.6e-121 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HMBAKEGM_00147 0.0 helD 3.6.4.12 L DNA helicase
HMBAKEGM_00148 1.2e-109 glnP P ABC transporter permease
HMBAKEGM_00149 6.9e-110 glnQ 3.6.3.21 E ABC transporter
HMBAKEGM_00150 6.1e-151 aatB ET ABC transporter substrate-binding protein
HMBAKEGM_00151 2.2e-78 yjcF S Acetyltransferase (GNAT) domain
HMBAKEGM_00152 1.3e-104 E GDSL-like Lipase/Acylhydrolase
HMBAKEGM_00153 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
HMBAKEGM_00154 3.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMBAKEGM_00155 4.1e-217 G Bacterial extracellular solute-binding protein
HMBAKEGM_00156 2.8e-67 S Peptidase propeptide and YPEB domain
HMBAKEGM_00158 1.3e-95 F Nucleoside 2-deoxyribosyltransferase
HMBAKEGM_00159 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HMBAKEGM_00160 9.3e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HMBAKEGM_00161 1.1e-167 V ABC transporter transmembrane region
HMBAKEGM_00162 7e-97 V ABC transporter transmembrane region
HMBAKEGM_00163 1.2e-140 pnuC H nicotinamide mononucleotide transporter
HMBAKEGM_00164 1.3e-11 S Protein of unknown function (DUF3290)
HMBAKEGM_00165 1e-41 S Protein of unknown function (DUF3290)
HMBAKEGM_00166 2.8e-159 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMBAKEGM_00167 2e-164 dnaQ 2.7.7.7 L EXOIII
HMBAKEGM_00168 8.5e-159 endA F DNA RNA non-specific endonuclease
HMBAKEGM_00169 2.7e-282 pipD E Dipeptidase
HMBAKEGM_00170 1.4e-203 malK P ATPases associated with a variety of cellular activities
HMBAKEGM_00171 1.9e-158 gtsB P ABC-type sugar transport systems, permease components
HMBAKEGM_00172 1e-145 gtsC P Binding-protein-dependent transport system inner membrane component
HMBAKEGM_00173 2.3e-256 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HMBAKEGM_00174 6.3e-238 G Bacterial extracellular solute-binding protein
HMBAKEGM_00175 2.2e-157 corA P CorA-like Mg2+ transporter protein
HMBAKEGM_00176 2.1e-158 3.5.2.6 V Beta-lactamase enzyme family
HMBAKEGM_00177 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
HMBAKEGM_00178 0.0 ydgH S MMPL family
HMBAKEGM_00179 1.7e-153
HMBAKEGM_00180 3.5e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HMBAKEGM_00181 1.3e-126 hipB K Helix-turn-helix
HMBAKEGM_00182 3.8e-08 hipB K Helix-turn-helix
HMBAKEGM_00183 2.6e-154 I alpha/beta hydrolase fold
HMBAKEGM_00184 2e-109 yjbF S SNARE associated Golgi protein
HMBAKEGM_00185 1.2e-97 J Acetyltransferase (GNAT) domain
HMBAKEGM_00186 2.9e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMBAKEGM_00187 7.3e-158 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HMBAKEGM_00188 4e-116 dedA S SNARE-like domain protein
HMBAKEGM_00189 9.2e-83 S Protein of unknown function (DUF1461)
HMBAKEGM_00190 6.3e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMBAKEGM_00191 1.8e-89 yutD S Protein of unknown function (DUF1027)
HMBAKEGM_00192 1.5e-277 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMBAKEGM_00193 1.1e-55
HMBAKEGM_00194 2.6e-263 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMBAKEGM_00195 6.4e-182 ccpA K catabolite control protein A
HMBAKEGM_00196 1.2e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMBAKEGM_00197 2e-43
HMBAKEGM_00198 3.3e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMBAKEGM_00199 4.1e-153 ykuT M mechanosensitive ion channel
HMBAKEGM_00200 1.2e-114 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMBAKEGM_00201 1.8e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMBAKEGM_00202 9.4e-68 yslB S Protein of unknown function (DUF2507)
HMBAKEGM_00203 4.6e-54 trxA O Belongs to the thioredoxin family
HMBAKEGM_00204 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMBAKEGM_00205 6.2e-51 yrzB S Belongs to the UPF0473 family
HMBAKEGM_00206 3.6e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMBAKEGM_00207 2e-42 yrzL S Belongs to the UPF0297 family
HMBAKEGM_00208 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMBAKEGM_00209 5.7e-44
HMBAKEGM_00210 4.3e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMBAKEGM_00211 8e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HMBAKEGM_00212 4.9e-75 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMBAKEGM_00213 3.9e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMBAKEGM_00214 7.5e-39 yajC U Preprotein translocase
HMBAKEGM_00215 6.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMBAKEGM_00216 7e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMBAKEGM_00217 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMBAKEGM_00218 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMBAKEGM_00219 2.9e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMBAKEGM_00220 3.9e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMBAKEGM_00221 3.4e-94 sip L Belongs to the 'phage' integrase family
HMBAKEGM_00222 5.9e-157 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMBAKEGM_00223 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMBAKEGM_00224 2.1e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
HMBAKEGM_00225 6.6e-113 yjbK S CYTH
HMBAKEGM_00226 5.1e-113 yjbH Q Thioredoxin
HMBAKEGM_00227 5e-159 coiA 3.6.4.12 S Competence protein
HMBAKEGM_00228 8.7e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMBAKEGM_00229 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMBAKEGM_00230 1.9e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMBAKEGM_00231 2.5e-40 ptsH G phosphocarrier protein HPR
HMBAKEGM_00232 4.1e-26
HMBAKEGM_00233 2.8e-42 L DDE superfamily endonuclease
HMBAKEGM_00234 0.0 clpE O Belongs to the ClpA ClpB family
HMBAKEGM_00235 3.9e-44 XK27_09445 S Domain of unknown function (DUF1827)
HMBAKEGM_00236 3.2e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMBAKEGM_00237 1.2e-160 hlyX S Transporter associated domain
HMBAKEGM_00238 1.3e-73
HMBAKEGM_00239 1.9e-86
HMBAKEGM_00240 2.7e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMBAKEGM_00241 3.9e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMBAKEGM_00242 1.1e-112 L COG3385 FOG Transposase and inactivated derivatives
HMBAKEGM_00243 6.9e-83 L COG3385 FOG Transposase and inactivated derivatives
HMBAKEGM_00244 5e-41 L COG3385 FOG Transposase and inactivated derivatives
HMBAKEGM_00245 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMBAKEGM_00246 2e-104 S Repeat protein
HMBAKEGM_00247 5.6e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HMBAKEGM_00248 1.2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMBAKEGM_00249 1.4e-56 XK27_04120 S Putative amino acid metabolism
HMBAKEGM_00250 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
HMBAKEGM_00251 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMBAKEGM_00252 1.9e-39
HMBAKEGM_00253 4.4e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HMBAKEGM_00254 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
HMBAKEGM_00255 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMBAKEGM_00256 1.2e-101 gpsB D DivIVA domain protein
HMBAKEGM_00257 3.3e-149 ylmH S S4 domain protein
HMBAKEGM_00258 9e-47 yggT S YGGT family
HMBAKEGM_00259 1.3e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMBAKEGM_00260 2.6e-207 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMBAKEGM_00261 3.4e-231 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMBAKEGM_00262 1.1e-72 S SLAP domain
HMBAKEGM_00263 3.8e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMBAKEGM_00264 1.8e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMBAKEGM_00265 4.3e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMBAKEGM_00266 7.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMBAKEGM_00267 1.9e-47 ftsI 3.4.16.4 M Penicillin-binding Protein
HMBAKEGM_00268 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HMBAKEGM_00269 1.4e-54 ftsL D Cell division protein FtsL
HMBAKEGM_00270 1.5e-183 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMBAKEGM_00271 1.8e-77 mraZ K Belongs to the MraZ family
HMBAKEGM_00272 2.2e-54 S Protein of unknown function (DUF3397)
HMBAKEGM_00273 6.5e-13 S Protein of unknown function (DUF4044)
HMBAKEGM_00274 4.5e-97 mreD
HMBAKEGM_00275 7.9e-149 mreC M Involved in formation and maintenance of cell shape
HMBAKEGM_00276 1.7e-174 mreB D cell shape determining protein MreB
HMBAKEGM_00277 2.1e-114 radC L DNA repair protein
HMBAKEGM_00278 5.7e-126 S Haloacid dehalogenase-like hydrolase
HMBAKEGM_00279 7.2e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMBAKEGM_00280 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMBAKEGM_00281 1.8e-39
HMBAKEGM_00282 1.4e-245 L transposase, IS605 OrfB family
HMBAKEGM_00283 1.5e-74 yfdH GT2 M Glycosyltransferase like family 2
HMBAKEGM_00284 1.9e-80 yfdH GT2 M Glycosyltransferase like family 2
HMBAKEGM_00285 3.1e-66 2.4.1.83 GT2 S GtrA-like protein
HMBAKEGM_00286 2.5e-45 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HMBAKEGM_00287 1.9e-10 EGP Major facilitator Superfamily
HMBAKEGM_00288 1.6e-111 EGP Major facilitator Superfamily
HMBAKEGM_00289 1.9e-143 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMBAKEGM_00290 9.2e-89 casE S CRISPR_assoc
HMBAKEGM_00291 1.3e-91 casD S CRISPR-associated protein (Cas_Cas5)
HMBAKEGM_00292 7.4e-152 casC L CT1975-like protein
HMBAKEGM_00293 9.7e-70 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMBAKEGM_00294 7.5e-117 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMBAKEGM_00295 1.1e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HMBAKEGM_00296 7.4e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMBAKEGM_00299 1.6e-21 psiE S Phosphate-starvation-inducible E
HMBAKEGM_00300 1.5e-74 Q Imidazolonepropionase and related amidohydrolases
HMBAKEGM_00301 1.7e-96 Q Imidazolonepropionase and related amidohydrolases
HMBAKEGM_00302 4.3e-63 oppA E ABC transporter
HMBAKEGM_00303 3.5e-43 oppA E ABC transporter
HMBAKEGM_00304 3.5e-47 oppA E ABC transporter
HMBAKEGM_00305 1.8e-76 oppA E ABC transporter
HMBAKEGM_00306 8e-67 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMBAKEGM_00307 3.1e-275 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMBAKEGM_00308 6.1e-219 naiP EGP Major facilitator Superfamily
HMBAKEGM_00309 2e-94 S Uncharacterised protein family (UPF0236)
HMBAKEGM_00310 6.1e-40 V ABC transporter transmembrane region
HMBAKEGM_00311 1.1e-93 V ABC transporter transmembrane region
HMBAKEGM_00313 1.4e-190 tcsA S ABC transporter substrate-binding protein PnrA-like
HMBAKEGM_00314 3.6e-285 xylG 3.6.3.17 S ABC transporter
HMBAKEGM_00315 1e-199 yufP S Belongs to the binding-protein-dependent transport system permease family
HMBAKEGM_00316 4.7e-166 yufQ S Belongs to the binding-protein-dependent transport system permease family
HMBAKEGM_00317 8.4e-143 K SIS domain
HMBAKEGM_00318 1e-159 degV S EDD domain protein, DegV family
HMBAKEGM_00319 7.7e-65
HMBAKEGM_00320 0.0 FbpA K Fibronectin-binding protein
HMBAKEGM_00321 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HMBAKEGM_00322 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMBAKEGM_00323 2.5e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMBAKEGM_00324 7.3e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMBAKEGM_00325 3.7e-31 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMBAKEGM_00326 1.1e-33
HMBAKEGM_00327 1.6e-80 cpdA S Calcineurin-like phosphoesterase
HMBAKEGM_00328 2.6e-87 cpdA S Calcineurin-like phosphoesterase
HMBAKEGM_00329 6.5e-11 cpdA S Calcineurin-like phosphoesterase
HMBAKEGM_00330 9.6e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMBAKEGM_00331 2.7e-70 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMBAKEGM_00332 1.7e-107 ypsA S Belongs to the UPF0398 family
HMBAKEGM_00333 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMBAKEGM_00334 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HMBAKEGM_00335 1.9e-112 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMBAKEGM_00336 7.4e-115 dnaD L DnaD domain protein
HMBAKEGM_00337 1.2e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HMBAKEGM_00338 2.9e-90 ypmB S Protein conserved in bacteria
HMBAKEGM_00339 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMBAKEGM_00340 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMBAKEGM_00341 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMBAKEGM_00342 9.6e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HMBAKEGM_00343 7.5e-180 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HMBAKEGM_00344 1.6e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HMBAKEGM_00345 6.7e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMBAKEGM_00346 1.1e-261 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HMBAKEGM_00347 1.1e-178
HMBAKEGM_00348 2.7e-140
HMBAKEGM_00349 3e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMBAKEGM_00350 7.8e-28
HMBAKEGM_00351 1.3e-111 rarA L recombination factor protein RarA
HMBAKEGM_00352 3.9e-33 rarA L recombination factor protein RarA
HMBAKEGM_00353 4.9e-10 rarA L recombination factor protein RarA
HMBAKEGM_00354 5.8e-130
HMBAKEGM_00355 5e-148
HMBAKEGM_00356 6.7e-148
HMBAKEGM_00357 2.8e-123 skfE V ATPases associated with a variety of cellular activities
HMBAKEGM_00358 3.9e-60 yvoA_1 K Transcriptional regulator, GntR family
HMBAKEGM_00359 8e-243 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMBAKEGM_00360 7.7e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMBAKEGM_00361 2.9e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMBAKEGM_00362 1.1e-29 mutT 3.6.1.55 F NUDIX domain
HMBAKEGM_00363 1.2e-125 S Peptidase family M23
HMBAKEGM_00364 6.4e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMBAKEGM_00365 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMBAKEGM_00366 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMBAKEGM_00367 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMBAKEGM_00368 3e-136 recO L Involved in DNA repair and RecF pathway recombination
HMBAKEGM_00369 1.1e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMBAKEGM_00370 1.6e-96 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMBAKEGM_00371 4.2e-175 phoH T phosphate starvation-inducible protein PhoH
HMBAKEGM_00372 3.2e-69 yqeY S YqeY-like protein
HMBAKEGM_00373 3.4e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMBAKEGM_00374 5.8e-152 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMBAKEGM_00375 6.8e-83 S Peptidase family M23
HMBAKEGM_00376 9.9e-163 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMBAKEGM_00377 1.7e-14
HMBAKEGM_00378 3.5e-106 K LysR substrate binding domain
HMBAKEGM_00379 1.1e-19
HMBAKEGM_00380 3.7e-213 S Sterol carrier protein domain
HMBAKEGM_00381 8.9e-98 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HMBAKEGM_00382 2.8e-52 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HMBAKEGM_00383 1.9e-66 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HMBAKEGM_00384 6.8e-110 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMBAKEGM_00385 3.9e-13 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMBAKEGM_00386 4.9e-44 arcA 3.5.3.6 E Arginine
HMBAKEGM_00387 9.7e-22 arcA 3.5.3.6 E Arginine
HMBAKEGM_00388 9e-58 arcA 3.5.3.6 E Arginine
HMBAKEGM_00389 3.2e-26 arcA 3.5.3.6 E Arginine
HMBAKEGM_00390 8.8e-156 lysR5 K LysR substrate binding domain
HMBAKEGM_00391 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HMBAKEGM_00392 1.6e-85 3.4.21.96 S SLAP domain
HMBAKEGM_00393 2e-68 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMBAKEGM_00394 2.5e-22 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMBAKEGM_00395 5.7e-89 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMBAKEGM_00396 4.2e-152 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HMBAKEGM_00397 8e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMBAKEGM_00398 3.7e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMBAKEGM_00399 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMBAKEGM_00400 2.1e-120 srtA 3.4.22.70 M sortase family
HMBAKEGM_00401 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMBAKEGM_00402 7.6e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMBAKEGM_00403 0.0 dnaK O Heat shock 70 kDa protein
HMBAKEGM_00404 5.1e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMBAKEGM_00405 2.5e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMBAKEGM_00406 2.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMBAKEGM_00407 2e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMBAKEGM_00408 4.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMBAKEGM_00409 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMBAKEGM_00410 1.2e-46 rplGA J ribosomal protein
HMBAKEGM_00411 8.8e-47 ylxR K Protein of unknown function (DUF448)
HMBAKEGM_00412 3e-196 nusA K Participates in both transcription termination and antitermination
HMBAKEGM_00413 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HMBAKEGM_00414 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMBAKEGM_00415 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMBAKEGM_00416 2.3e-197 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMBAKEGM_00417 4.6e-146 cdsA 2.7.7.41 I Belongs to the CDS family
HMBAKEGM_00418 1.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMBAKEGM_00419 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMBAKEGM_00420 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMBAKEGM_00421 2.2e-185 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMBAKEGM_00422 4.2e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
HMBAKEGM_00423 2.3e-198 yabB 2.1.1.223 L Methyltransferase small domain
HMBAKEGM_00424 4.1e-115 plsC 2.3.1.51 I Acyltransferase
HMBAKEGM_00425 1.4e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HMBAKEGM_00426 0.0 pepO 3.4.24.71 O Peptidase family M13
HMBAKEGM_00427 1.6e-271 mdlB V ABC transporter
HMBAKEGM_00428 8.4e-141 mdlA V ABC transporter
HMBAKEGM_00429 2.5e-30 yneF S Uncharacterised protein family (UPF0154)
HMBAKEGM_00430 5.1e-38 ynzC S UPF0291 protein
HMBAKEGM_00431 3.6e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMBAKEGM_00432 4.8e-148 E GDSL-like Lipase/Acylhydrolase family
HMBAKEGM_00433 6e-45 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMBAKEGM_00434 1.5e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMBAKEGM_00435 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMBAKEGM_00436 1.5e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMBAKEGM_00437 4.5e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMBAKEGM_00438 2.2e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMBAKEGM_00439 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMBAKEGM_00440 1.4e-133 L Transposase and inactivated derivatives, IS30 family
HMBAKEGM_00441 4.9e-260 yfnA E amino acid
HMBAKEGM_00442 5.2e-44
HMBAKEGM_00443 1.7e-289 pipD E Dipeptidase
HMBAKEGM_00444 1.3e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMBAKEGM_00445 0.0 smc D Required for chromosome condensation and partitioning
HMBAKEGM_00446 1.3e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMBAKEGM_00447 9.4e-302 oppA E ABC transporter substrate-binding protein
HMBAKEGM_00448 0.0 oppA E ABC transporter substrate-binding protein
HMBAKEGM_00449 6.6e-149 oppC P Binding-protein-dependent transport system inner membrane component
HMBAKEGM_00450 1.7e-176 oppB P ABC transporter permease
HMBAKEGM_00451 6.9e-181 oppF P Belongs to the ABC transporter superfamily
HMBAKEGM_00452 7.3e-197 oppD P Belongs to the ABC transporter superfamily
HMBAKEGM_00453 3.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMBAKEGM_00454 9.9e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMBAKEGM_00455 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMBAKEGM_00456 1.1e-306 yloV S DAK2 domain fusion protein YloV
HMBAKEGM_00457 6.8e-57 asp S Asp23 family, cell envelope-related function
HMBAKEGM_00458 1.1e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMBAKEGM_00459 1.6e-51
HMBAKEGM_00460 1.4e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMBAKEGM_00461 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMBAKEGM_00462 2.6e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMBAKEGM_00463 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HMBAKEGM_00464 2.4e-147 stp 3.1.3.16 T phosphatase
HMBAKEGM_00465 2e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMBAKEGM_00466 6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMBAKEGM_00467 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMBAKEGM_00468 6.5e-34 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMBAKEGM_00469 1.9e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HMBAKEGM_00470 8.1e-44 6.3.3.2 S ASCH
HMBAKEGM_00471 3.5e-21 6.3.3.2 S ASCH
HMBAKEGM_00472 2.5e-308 recN L May be involved in recombinational repair of damaged DNA
HMBAKEGM_00473 6e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HMBAKEGM_00474 2.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMBAKEGM_00475 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMBAKEGM_00476 1.2e-194 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMBAKEGM_00477 1.3e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMBAKEGM_00478 1.8e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMBAKEGM_00479 1.8e-69 yqhY S Asp23 family, cell envelope-related function
HMBAKEGM_00480 2.2e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMBAKEGM_00481 8.9e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMBAKEGM_00482 2.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMBAKEGM_00483 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMBAKEGM_00484 1e-243 S Uncharacterized protein conserved in bacteria (DUF2325)
HMBAKEGM_00485 1.8e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HMBAKEGM_00486 2.5e-129 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HMBAKEGM_00487 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMBAKEGM_00488 0.0 S Predicted membrane protein (DUF2207)
HMBAKEGM_00489 6.2e-211 M Glycosyl hydrolases family 25
HMBAKEGM_00491 5e-178 I Carboxylesterase family
HMBAKEGM_00492 3e-65 arsC 1.20.4.1 P Belongs to the ArsC family
HMBAKEGM_00493 1.7e-21
HMBAKEGM_00494 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMBAKEGM_00495 2.5e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HMBAKEGM_00496 2e-48
HMBAKEGM_00497 6.8e-152 glcU U sugar transport
HMBAKEGM_00499 1.7e-43
HMBAKEGM_00500 5.4e-107 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMBAKEGM_00501 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMBAKEGM_00502 1.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMBAKEGM_00503 3.2e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMBAKEGM_00504 7.1e-49 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMBAKEGM_00505 2.8e-122 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMBAKEGM_00506 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMBAKEGM_00507 3.7e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMBAKEGM_00508 6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMBAKEGM_00509 1e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMBAKEGM_00510 2.3e-33 S RelB antitoxin
HMBAKEGM_00511 4.9e-58 yufP S Belongs to the binding-protein-dependent transport system permease family
HMBAKEGM_00512 1.4e-26 yufQ S Belongs to the binding-protein-dependent transport system permease family
HMBAKEGM_00513 1.2e-112 yufQ S Belongs to the binding-protein-dependent transport system permease family
HMBAKEGM_00514 0.0 3.6.3.8 P P-type ATPase
HMBAKEGM_00515 2.1e-31 S Archaea bacterial proteins of unknown function
HMBAKEGM_00516 4.3e-95 M NlpC/P60 family
HMBAKEGM_00517 1.7e-96 gmk2 2.7.4.8 F Guanylate kinase homologues.
HMBAKEGM_00518 4.3e-25
HMBAKEGM_00519 1.5e-280 S O-antigen ligase like membrane protein
HMBAKEGM_00520 3.3e-95
HMBAKEGM_00521 1.2e-74 nrdI F Belongs to the NrdI family
HMBAKEGM_00522 4e-11 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMBAKEGM_00523 7.8e-20
HMBAKEGM_00524 1.6e-67
HMBAKEGM_00525 8.1e-82 S Threonine/Serine exporter, ThrE
HMBAKEGM_00526 6.7e-139 thrE S Putative threonine/serine exporter
HMBAKEGM_00527 2.2e-290 S ABC transporter
HMBAKEGM_00528 5e-55
HMBAKEGM_00529 8.4e-99 rimL J Acetyltransferase (GNAT) domain
HMBAKEGM_00530 1.9e-20 S Protein of unknown function (DUF554)
HMBAKEGM_00531 2.4e-215 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMBAKEGM_00532 0.0 pepF E oligoendopeptidase F
HMBAKEGM_00533 1.5e-09 Z012_06740 S Fic/DOC family
HMBAKEGM_00534 9.1e-42 Z012_06740 S Fic/DOC family
HMBAKEGM_00535 2e-50 lctP C L-lactate permease
HMBAKEGM_00536 2.1e-90 lctP C L-lactate permease
HMBAKEGM_00537 1.6e-239 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMBAKEGM_00538 1.1e-131 znuB U ABC 3 transport family
HMBAKEGM_00539 2.5e-118 fhuC P ABC transporter
HMBAKEGM_00540 4e-159 psaA P Belongs to the bacterial solute-binding protein 9 family
HMBAKEGM_00541 1e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
HMBAKEGM_00542 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HMBAKEGM_00543 1.1e-97 fruR K DeoR C terminal sensor domain
HMBAKEGM_00546 8.7e-27
HMBAKEGM_00547 7.1e-33
HMBAKEGM_00548 1e-34 yozG K Transcriptional regulator
HMBAKEGM_00549 6.9e-71 S Enterocin A Immunity
HMBAKEGM_00550 4.1e-115 S Archaea bacterial proteins of unknown function
HMBAKEGM_00551 4.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HMBAKEGM_00552 3.2e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMBAKEGM_00553 1.4e-209 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HMBAKEGM_00554 5.1e-122 K response regulator
HMBAKEGM_00555 0.0 V ABC transporter
HMBAKEGM_00556 1.3e-307 V ABC transporter, ATP-binding protein
HMBAKEGM_00557 8.9e-139 XK27_01040 S Protein of unknown function (DUF1129)
HMBAKEGM_00558 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMBAKEGM_00559 2.1e-44 yyzM S Bacterial protein of unknown function (DUF951)
HMBAKEGM_00560 2.9e-154 spo0J K Belongs to the ParB family
HMBAKEGM_00561 3.4e-138 soj D Sporulation initiation inhibitor
HMBAKEGM_00562 1.6e-149 noc K Belongs to the ParB family
HMBAKEGM_00563 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HMBAKEGM_00564 6.6e-85 cvpA S Colicin V production protein
HMBAKEGM_00565 1.7e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMBAKEGM_00566 8.7e-150 3.1.3.48 T Tyrosine phosphatase family
HMBAKEGM_00567 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
HMBAKEGM_00568 5.3e-98 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HMBAKEGM_00569 9.1e-36 S Uncharacterised protein family (UPF0236)
HMBAKEGM_00570 4.6e-217 G Major Facilitator Superfamily
HMBAKEGM_00571 5.7e-112 K WHG domain
HMBAKEGM_00572 6.1e-38
HMBAKEGM_00573 2.2e-276 pipD E Dipeptidase
HMBAKEGM_00574 8.8e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HMBAKEGM_00575 5.6e-168 hrtB V ABC transporter permease
HMBAKEGM_00576 7e-95 ygfC K Bacterial regulatory proteins, tetR family
HMBAKEGM_00577 9.3e-112 G phosphoglycerate mutase
HMBAKEGM_00578 9.8e-143 aroD S Alpha/beta hydrolase family
HMBAKEGM_00579 6.9e-144 S Belongs to the UPF0246 family
HMBAKEGM_00580 2.4e-121
HMBAKEGM_00581 7.5e-51 2.7.7.12 C Domain of unknown function (DUF4931)
HMBAKEGM_00582 0.0 pepN 3.4.11.2 E aminopeptidase
HMBAKEGM_00583 5e-60 lysM M LysM domain
HMBAKEGM_00584 1.5e-172
HMBAKEGM_00585 1.7e-211 mdtG EGP Major facilitator Superfamily
HMBAKEGM_00587 8.7e-116 lsa S ABC transporter
HMBAKEGM_00588 4.3e-244 purD 6.3.4.13 F Belongs to the GARS family
HMBAKEGM_00589 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HMBAKEGM_00590 4.9e-201 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HMBAKEGM_00591 2.4e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMBAKEGM_00592 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMBAKEGM_00593 8.8e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMBAKEGM_00594 1.3e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMBAKEGM_00595 1.1e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HMBAKEGM_00596 3.9e-220 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMBAKEGM_00597 1.3e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMBAKEGM_00598 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMBAKEGM_00599 3.6e-137 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMBAKEGM_00600 7.5e-192 ydiM G Major Facilitator Superfamily
HMBAKEGM_00601 1.5e-21 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMBAKEGM_00602 1.2e-115 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMBAKEGM_00604 0.0 lacS G Transporter
HMBAKEGM_00605 4e-57 lacS G Transporter
HMBAKEGM_00606 5.9e-70 lacS G Transporter
HMBAKEGM_00607 6.8e-48 lacS G Transporter
HMBAKEGM_00608 6e-24 lacS G Transporter
HMBAKEGM_00609 4.9e-190 lacR K Transcriptional regulator
HMBAKEGM_00610 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HMBAKEGM_00611 9.7e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HMBAKEGM_00612 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMBAKEGM_00613 2.9e-150
HMBAKEGM_00614 1.1e-164
HMBAKEGM_00615 2.9e-136
HMBAKEGM_00616 1.4e-264 glnA 6.3.1.2 E glutamine synthetase
HMBAKEGM_00617 2.4e-64 ynbB 4.4.1.1 P aluminum resistance
HMBAKEGM_00618 5.5e-21 ynbB 4.4.1.1 P aluminum resistance
HMBAKEGM_00619 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMBAKEGM_00620 1.7e-69 yqhL P Rhodanese-like protein
HMBAKEGM_00621 5.6e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HMBAKEGM_00622 1.5e-113 gluP 3.4.21.105 S Rhomboid family
HMBAKEGM_00623 1.7e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMBAKEGM_00624 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMBAKEGM_00625 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HMBAKEGM_00626 0.0 S membrane
HMBAKEGM_00627 1e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HMBAKEGM_00628 2.4e-38 K Helix-turn-helix domain
HMBAKEGM_00629 2.9e-57 S Phage derived protein Gp49-like (DUF891)
HMBAKEGM_00630 8.7e-170 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HMBAKEGM_00631 1.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMBAKEGM_00632 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMBAKEGM_00633 1.4e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMBAKEGM_00634 1.6e-48 yodB K Transcriptional regulator, HxlR family
HMBAKEGM_00635 3e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMBAKEGM_00636 2.2e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMBAKEGM_00637 4.4e-156 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMBAKEGM_00638 2.7e-85 S Aminoacyl-tRNA editing domain
HMBAKEGM_00639 3.2e-281 arlS 2.7.13.3 T Histidine kinase
HMBAKEGM_00640 3.2e-127 K response regulator
HMBAKEGM_00641 4.1e-98 yceD S Uncharacterized ACR, COG1399
HMBAKEGM_00642 1.7e-215 ylbM S Belongs to the UPF0348 family
HMBAKEGM_00643 6.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMBAKEGM_00644 2.3e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HMBAKEGM_00645 1.2e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMBAKEGM_00646 1.3e-212 yqeH S Ribosome biogenesis GTPase YqeH
HMBAKEGM_00647 1.3e-93 yqeG S HAD phosphatase, family IIIA
HMBAKEGM_00648 5.1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMBAKEGM_00649 6.2e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMBAKEGM_00650 1.5e-56 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMBAKEGM_00651 6.1e-238 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HMBAKEGM_00652 3.5e-29 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HMBAKEGM_00653 2e-185 S Domain of unknown function (DUF389)
HMBAKEGM_00654 4.7e-44
HMBAKEGM_00655 1.2e-37
HMBAKEGM_00656 1.6e-91
HMBAKEGM_00657 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMBAKEGM_00658 4e-167 dnaI L Primosomal protein DnaI
HMBAKEGM_00659 2.1e-249 dnaB L Replication initiation and membrane attachment
HMBAKEGM_00660 4.1e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMBAKEGM_00661 1.2e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMBAKEGM_00662 5.3e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMBAKEGM_00663 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMBAKEGM_00664 1e-28 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMBAKEGM_00665 3e-123 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMBAKEGM_00666 1.4e-29 cas4 3.1.12.1 L Domain of unknown function DUF83
HMBAKEGM_00667 2.4e-09 cas4 3.1.12.1 L Domain of unknown function DUF83
HMBAKEGM_00668 2.2e-180 cas3 L CRISPR-associated helicase cas3
HMBAKEGM_00669 1.1e-66 cas5t L CRISPR-associated protein Cas5
HMBAKEGM_00670 1.3e-104 cst2 L CRISPR-associated negative auto-regulator DevR/Csa2
HMBAKEGM_00671 1.5e-106 cst1 S CRISPR-associated protein (Cas_CXXC_CXXC)
HMBAKEGM_00672 4e-43 cas6 L CRISPR associated protein Cas6
HMBAKEGM_00673 1.3e-136 purD 6.3.4.13 F Belongs to the GARS family
HMBAKEGM_00674 3.4e-16 darA C Flavodoxin
HMBAKEGM_00675 2e-67 darA C Flavodoxin
HMBAKEGM_00676 4.8e-141 qmcA O prohibitin homologues
HMBAKEGM_00677 1.3e-51 L RelB antitoxin
HMBAKEGM_00678 3.1e-14
HMBAKEGM_00679 2.9e-195 S Bacteriocin helveticin-J
HMBAKEGM_00680 4.3e-291 M Peptidase family M1 domain
HMBAKEGM_00681 2.3e-176 S SLAP domain
HMBAKEGM_00682 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMBAKEGM_00683 6.3e-56 S Psort location Cytoplasmic, score
HMBAKEGM_00684 0.0 O Belongs to the peptidase S8 family
HMBAKEGM_00685 6.9e-64 V efflux transmembrane transporter activity
HMBAKEGM_00686 1.8e-264
HMBAKEGM_00687 3.3e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMBAKEGM_00688 7.3e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMBAKEGM_00689 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMBAKEGM_00690 1.4e-215 ecsB U ABC transporter
HMBAKEGM_00691 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HMBAKEGM_00692 1.4e-53 higA K Helix-turn-helix XRE-family like proteins
HMBAKEGM_00693 3.3e-34 S Plasmid maintenance system killer
HMBAKEGM_00694 3.1e-80 hit FG Scavenger mRNA decapping enzyme C-term binding
HMBAKEGM_00695 8e-28
HMBAKEGM_00696 1.9e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMBAKEGM_00697 6.2e-78 S PAS domain
HMBAKEGM_00698 1.5e-188 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMBAKEGM_00699 0.0 L AAA domain
HMBAKEGM_00700 1.8e-231 yhaO L Ser Thr phosphatase family protein
HMBAKEGM_00701 9.4e-56 yheA S Belongs to the UPF0342 family
HMBAKEGM_00702 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMBAKEGM_00703 1.4e-21 bglH 3.2.1.86 GT1 G beta-glucosidase activity
HMBAKEGM_00704 1.9e-09 5.3.3.2 C FMN-dependent dehydrogenase
HMBAKEGM_00705 6.9e-136 mgtC S MgtC family
HMBAKEGM_00706 5.6e-138 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HMBAKEGM_00707 9.8e-55
HMBAKEGM_00708 3.1e-150 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HMBAKEGM_00709 2.1e-19 UW LPXTG-motif cell wall anchor domain protein
HMBAKEGM_00711 1.2e-154 yitS S EDD domain protein, DegV family
HMBAKEGM_00712 1.1e-81 racA K Domain of unknown function (DUF1836)
HMBAKEGM_00713 2.3e-243 L Probable transposase
HMBAKEGM_00714 1.7e-32 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMBAKEGM_00716 5.3e-43
HMBAKEGM_00717 2.6e-46 K Helix-turn-helix XRE-family like proteins
HMBAKEGM_00718 3.3e-14 S Phage derived protein Gp49-like (DUF891)
HMBAKEGM_00719 1.2e-08
HMBAKEGM_00720 4.4e-16 L PFAM IS66 Orf2 family protein
HMBAKEGM_00722 8.3e-285 V ABC-type multidrug transport system, ATPase and permease components
HMBAKEGM_00723 5.6e-289 V ABC-type multidrug transport system, ATPase and permease components
HMBAKEGM_00724 1.7e-31
HMBAKEGM_00725 1.1e-38
HMBAKEGM_00726 1.5e-89 3.6.1.55 L NUDIX domain
HMBAKEGM_00727 3.5e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HMBAKEGM_00728 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HMBAKEGM_00730 3.9e-113 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMBAKEGM_00731 2.2e-104 padC Q Phenolic acid decarboxylase
HMBAKEGM_00732 5.2e-78 padR K Virulence activator alpha C-term
HMBAKEGM_00733 1.5e-110 M ErfK YbiS YcfS YnhG
HMBAKEGM_00734 4.3e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMBAKEGM_00735 2.2e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMBAKEGM_00737 3.7e-48 pspC KT PspC domain
HMBAKEGM_00738 1e-31 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
HMBAKEGM_00739 1.6e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMBAKEGM_00740 2.4e-29 Q DSBA-like thioredoxin domain
HMBAKEGM_00741 1.2e-18 frnE Q DSBA-like thioredoxin domain
HMBAKEGM_00742 1.7e-10 frnE Q DSBA-like thioredoxin domain
HMBAKEGM_00743 4.1e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMBAKEGM_00744 9.4e-118 M1-798 K Rhodanese Homology Domain
HMBAKEGM_00745 1.4e-57 CO Thioredoxin
HMBAKEGM_00746 2.7e-19 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
HMBAKEGM_00747 9.6e-35 infB UW LPXTG-motif cell wall anchor domain protein
HMBAKEGM_00748 6.8e-18 infB UW LPXTG-motif cell wall anchor domain protein
HMBAKEGM_00749 2.5e-35 infB UW LPXTG-motif cell wall anchor domain protein
HMBAKEGM_00750 6.5e-65 O Belongs to the peptidase S8 family
HMBAKEGM_00751 1.3e-93 O Belongs to the peptidase S8 family
HMBAKEGM_00752 5.8e-297 ytgP S Polysaccharide biosynthesis protein
HMBAKEGM_00753 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMBAKEGM_00754 3.5e-120 3.6.1.27 I Acid phosphatase homologues
HMBAKEGM_00755 1.1e-67 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMBAKEGM_00756 5.7e-264 qacA EGP Major facilitator Superfamily
HMBAKEGM_00757 2.5e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMBAKEGM_00760 8.8e-178 psaA P Belongs to the bacterial solute-binding protein 9 family
HMBAKEGM_00762 4.3e-43 S COG NOG14552 non supervised orthologous group
HMBAKEGM_00763 5.3e-79
HMBAKEGM_00764 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMBAKEGM_00765 1.2e-238 nfrB 2.4.1.336 GT2 M Glycosyltransferase like family 2
HMBAKEGM_00767 2.3e-205 EGP Major facilitator Superfamily
HMBAKEGM_00768 1.7e-103 tnpR1 L Resolvase, N terminal domain
HMBAKEGM_00771 6.5e-47
HMBAKEGM_00772 1.6e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HMBAKEGM_00773 6.1e-219 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HMBAKEGM_00774 7.8e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HMBAKEGM_00775 2.4e-126 L transposase, IS605 OrfB family
HMBAKEGM_00776 9.6e-27 L transposase, IS605 OrfB family
HMBAKEGM_00777 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMBAKEGM_00778 1.4e-151 yihY S Belongs to the UPF0761 family
HMBAKEGM_00779 8.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
HMBAKEGM_00780 1.6e-79 fld C Flavodoxin
HMBAKEGM_00781 3.1e-90 gtcA S Teichoic acid glycosylation protein
HMBAKEGM_00782 3.8e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMBAKEGM_00783 1.2e-25
HMBAKEGM_00785 2.4e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMBAKEGM_00786 1.1e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
HMBAKEGM_00787 8.9e-130 M Glycosyl hydrolases family 25
HMBAKEGM_00788 4.3e-37 potE E amino acid
HMBAKEGM_00789 5.4e-156 potE E amino acid
HMBAKEGM_00790 2.2e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMBAKEGM_00791 1.1e-240 yhdP S Transporter associated domain
HMBAKEGM_00792 1.5e-53 C nitroreductase
HMBAKEGM_00793 2.5e-18 C nitroreductase
HMBAKEGM_00794 3.7e-39
HMBAKEGM_00795 1.1e-161 rssA S Phospholipase, patatin family
HMBAKEGM_00796 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HMBAKEGM_00797 1.4e-128 glcR K DeoR C terminal sensor domain
HMBAKEGM_00798 3.2e-62 S Enterocin A Immunity
HMBAKEGM_00799 2.5e-55 yitW S Iron-sulfur cluster assembly protein
HMBAKEGM_00800 3.2e-272 sufB O assembly protein SufB
HMBAKEGM_00801 3.8e-81 nifU C SUF system FeS assembly protein, NifU family
HMBAKEGM_00802 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMBAKEGM_00803 1.8e-229 sufD O FeS assembly protein SufD
HMBAKEGM_00804 3.4e-146 sufC O FeS assembly ATPase SufC
HMBAKEGM_00805 2.7e-154 S hydrolase
HMBAKEGM_00806 4.8e-38 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HMBAKEGM_00807 1.5e-74 gntR K UbiC transcription regulator-associated domain protein
HMBAKEGM_00808 7.6e-21 gntR K UbiC transcription regulator-associated domain protein
HMBAKEGM_00809 4.8e-176 rihB 3.2.2.1 F Nucleoside
HMBAKEGM_00810 0.0 kup P Transport of potassium into the cell
HMBAKEGM_00811 2e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMBAKEGM_00812 1.2e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMBAKEGM_00813 1.6e-162 2.7.7.12 C Domain of unknown function (DUF4931)
HMBAKEGM_00814 7.9e-32 S Uncharacterised protein family (UPF0236)
HMBAKEGM_00815 1.2e-32 S Uncharacterised protein family (UPF0236)
HMBAKEGM_00816 8.6e-41 gcvR T Belongs to the UPF0237 family
HMBAKEGM_00817 4.5e-247 XK27_08635 S UPF0210 protein
HMBAKEGM_00818 1.4e-237 G Bacterial extracellular solute-binding protein
HMBAKEGM_00819 1.6e-88 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMBAKEGM_00820 5.5e-62 S Protein of unknown function (DUF2974)
HMBAKEGM_00821 2.8e-109 glnP P ABC transporter permease
HMBAKEGM_00822 6.7e-108 gluC P ABC transporter permease
HMBAKEGM_00823 1.5e-152 glnH ET ABC transporter substrate-binding protein
HMBAKEGM_00824 3.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMBAKEGM_00825 7.6e-103 S ABC-type cobalt transport system, permease component
HMBAKEGM_00826 0.0 V ABC transporter transmembrane region
HMBAKEGM_00827 4.9e-286 XK27_09600 V ABC transporter, ATP-binding protein
HMBAKEGM_00828 8.8e-81 K Transcriptional regulator, MarR family
HMBAKEGM_00829 9.9e-149 glnH ET ABC transporter
HMBAKEGM_00830 4.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HMBAKEGM_00831 2e-123
HMBAKEGM_00832 6.2e-11
HMBAKEGM_00833 3.4e-310 ybiT S ABC transporter, ATP-binding protein
HMBAKEGM_00834 1.1e-208 pepA E M42 glutamyl aminopeptidase
HMBAKEGM_00835 9.6e-217 mdtG EGP Major facilitator Superfamily
HMBAKEGM_00836 1.6e-261 emrY EGP Major facilitator Superfamily
HMBAKEGM_00838 1.5e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMBAKEGM_00839 2.6e-239 pyrP F Permease
HMBAKEGM_00840 5e-39 S reductase
HMBAKEGM_00841 2.3e-41 S reductase
HMBAKEGM_00842 2e-23 emrY EGP Major facilitator Superfamily
HMBAKEGM_00843 1e-29 emrY EGP Major facilitator Superfamily
HMBAKEGM_00848 1.7e-95 MA20_25245 K Acetyltransferase (GNAT) domain
HMBAKEGM_00849 2.6e-25
HMBAKEGM_00853 2e-29 cspA K Cold shock protein
HMBAKEGM_00854 1.6e-24 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMBAKEGM_00855 9.3e-152 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HMBAKEGM_00856 1.7e-229 mtnE 2.6.1.83 E Aminotransferase
HMBAKEGM_00857 4.3e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMBAKEGM_00859 3.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMBAKEGM_00860 9.2e-248 nhaC C Na H antiporter NhaC
HMBAKEGM_00861 3.5e-55
HMBAKEGM_00862 4.9e-120 ybhL S Belongs to the BI1 family
HMBAKEGM_00863 1.4e-114 S Protein of unknown function (DUF1211)
HMBAKEGM_00864 1.1e-169 yegS 2.7.1.107 G Lipid kinase
HMBAKEGM_00865 2.9e-276 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMBAKEGM_00866 9.9e-261 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMBAKEGM_00867 5.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMBAKEGM_00868 4.4e-211 camS S sex pheromone
HMBAKEGM_00869 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMBAKEGM_00870 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMBAKEGM_00871 5e-103 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HMBAKEGM_00873 2.1e-87 ydcK S Belongs to the SprT family
HMBAKEGM_00874 5.7e-137 M Glycosyltransferase sugar-binding region containing DXD motif
HMBAKEGM_00875 1.7e-260 epsU S Polysaccharide biosynthesis protein
HMBAKEGM_00876 1.9e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMBAKEGM_00877 3.2e-167 pacL 3.6.3.8 P P-type ATPase
HMBAKEGM_00878 2.5e-128 pacL 3.6.3.8 P P-type ATPase
HMBAKEGM_00879 5.6e-21 pacL 3.6.3.8 P P-type ATPase
HMBAKEGM_00880 1.6e-57 pacL 3.6.3.8 P P-type ATPase
HMBAKEGM_00881 2.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMBAKEGM_00882 1e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMBAKEGM_00883 7e-206 csaB M Glycosyl transferases group 1
HMBAKEGM_00884 8.6e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMBAKEGM_00885 1.8e-55 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HMBAKEGM_00886 8.7e-122 gntR1 K UTRA
HMBAKEGM_00887 4.1e-214
HMBAKEGM_00890 4.1e-133 slpX S SLAP domain
HMBAKEGM_00891 9.5e-11 pfoS S Phosphotransferase system, EIIC
HMBAKEGM_00892 5.9e-77 pfoS S Phosphotransferase system, EIIC
HMBAKEGM_00893 1.5e-19 pfoS S Phosphotransferase system, EIIC
HMBAKEGM_00895 1.7e-133 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMBAKEGM_00896 1.7e-229 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HMBAKEGM_00897 9e-112 G Phosphoglycerate mutase family
HMBAKEGM_00898 1.7e-196 D nuclear chromosome segregation
HMBAKEGM_00899 5.6e-68 M LysM domain protein
HMBAKEGM_00900 5.6e-13
HMBAKEGM_00901 2.7e-21 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HMBAKEGM_00902 1.6e-48 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HMBAKEGM_00903 3.9e-29 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HMBAKEGM_00904 5.4e-68
HMBAKEGM_00905 7.1e-32
HMBAKEGM_00906 1.4e-71 S Iron-sulphur cluster biosynthesis
HMBAKEGM_00907 2.8e-229 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMBAKEGM_00908 1.3e-128 XK27_08435 K UTRA
HMBAKEGM_00910 3e-26 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMBAKEGM_00911 5.3e-141 S Uncharacterized protein conserved in bacteria (DUF2263)
HMBAKEGM_00912 5.1e-60
HMBAKEGM_00913 1.8e-28 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HMBAKEGM_00914 8.6e-105 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HMBAKEGM_00915 1.6e-94 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HMBAKEGM_00916 7.7e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HMBAKEGM_00917 6.4e-37
HMBAKEGM_00918 1.3e-136 4.1.1.44 S Carboxymuconolactone decarboxylase family
HMBAKEGM_00919 1.4e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMBAKEGM_00920 4.7e-35 S LPXTG cell wall anchor motif
HMBAKEGM_00921 9.6e-89 UW LPXTG-motif cell wall anchor domain protein
HMBAKEGM_00922 2.8e-49
HMBAKEGM_00923 2.2e-45 yagE E amino acid
HMBAKEGM_00924 8.8e-47
HMBAKEGM_00925 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMBAKEGM_00926 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMBAKEGM_00927 5.8e-242 cycA E Amino acid permease
HMBAKEGM_00928 3.7e-61 maa S transferase hexapeptide repeat
HMBAKEGM_00929 4e-10 maa S transferase hexapeptide repeat
HMBAKEGM_00930 9.1e-64 K Transcriptional regulator
HMBAKEGM_00931 1.2e-64 K Transcriptional regulator
HMBAKEGM_00932 2.9e-63 manO S Domain of unknown function (DUF956)
HMBAKEGM_00933 1.2e-174 manN G system, mannose fructose sorbose family IID component
HMBAKEGM_00934 1.4e-134 manY G PTS system
HMBAKEGM_00935 3.6e-188 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HMBAKEGM_00936 1.8e-16 rafA 3.2.1.22 G alpha-galactosidase
HMBAKEGM_00937 1.8e-67
HMBAKEGM_00938 3.8e-87 adk 2.7.4.3 F topology modulation protein
HMBAKEGM_00939 1.2e-109 XK27_00160 S Domain of unknown function (DUF5052)
HMBAKEGM_00940 1.4e-54
HMBAKEGM_00941 8.2e-28 M Glycosyl hydrolases family 25
HMBAKEGM_00942 2.5e-44 M Glycosyl hydrolases family 25
HMBAKEGM_00943 1.1e-47 M Glycosyl hydrolases family 25
HMBAKEGM_00944 3.6e-13 lysA2 M Glycosyl hydrolases family 25
HMBAKEGM_00945 3.2e-34 S Transglycosylase associated protein
HMBAKEGM_00946 2.6e-96 yoaK S Protein of unknown function (DUF1275)
HMBAKEGM_00947 2.1e-55 K Helix-turn-helix domain
HMBAKEGM_00948 1.7e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMBAKEGM_00949 1.1e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
HMBAKEGM_00950 2.4e-170 K Transcriptional regulator
HMBAKEGM_00951 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMBAKEGM_00952 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMBAKEGM_00953 6.5e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMBAKEGM_00954 1.3e-18 snf 2.7.11.1 KL domain protein
HMBAKEGM_00955 3.2e-210 snf 2.7.11.1 KL domain protein
HMBAKEGM_00956 1.2e-85 dps P Belongs to the Dps family
HMBAKEGM_00957 1.3e-93 K acetyltransferase
HMBAKEGM_00958 8.4e-153 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HMBAKEGM_00959 1e-84 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMBAKEGM_00960 1.5e-106 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMBAKEGM_00961 3e-39 K Bacterial regulatory proteins, tetR family
HMBAKEGM_00962 5.2e-18 K Bacterial regulatory proteins, tetR family
HMBAKEGM_00963 1e-27 1.1.1.3 T phosphoserine phosphatase activity
HMBAKEGM_00964 1.7e-08 1.1.1.3 T phosphoserine phosphatase activity
HMBAKEGM_00965 9.2e-141 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMBAKEGM_00966 1.8e-38 S Hydrolases of the alpha beta superfamily
HMBAKEGM_00967 1.8e-57 S Alpha beta hydrolase
HMBAKEGM_00968 1.1e-36 K Acetyltransferase (GNAT) family
HMBAKEGM_00969 6.2e-48 K Acetyltransferase (GNAT) family
HMBAKEGM_00970 2e-255 gor 1.8.1.7 C Glutathione reductase
HMBAKEGM_00971 2.1e-08
HMBAKEGM_00973 9.9e-117 L Integrase
HMBAKEGM_00974 1.7e-90 dam 2.1.1.72 H Site-specific DNA-methyltransferase (adenine-specific)
HMBAKEGM_00975 4.2e-197 L hmm pf00665
HMBAKEGM_00976 1.7e-42 L Helix-turn-helix domain
HMBAKEGM_00977 3.6e-73 L Helix-turn-helix domain
HMBAKEGM_00978 9.1e-161 cjaA ET ABC transporter substrate-binding protein
HMBAKEGM_00979 8.2e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMBAKEGM_00980 4e-79 P ABC transporter permease
HMBAKEGM_00981 6e-112 papP P ABC transporter, permease protein
HMBAKEGM_00982 3.4e-25 S Uncharacterized protein conserved in bacteria (DUF2255)
HMBAKEGM_00983 3.1e-43 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HMBAKEGM_00984 1.5e-48 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
HMBAKEGM_00985 3.1e-98 3.6.1.55, 3.6.1.67 F NUDIX domain
HMBAKEGM_00986 3.9e-201 folP 2.5.1.15 H dihydropteroate synthase
HMBAKEGM_00987 2.4e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMBAKEGM_00988 1.3e-201 folE 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 F GTP cyclohydrolase 1
HMBAKEGM_00989 6.5e-57 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMBAKEGM_00990 8e-125 magIII L Base excision DNA repair protein, HhH-GPD family
HMBAKEGM_00991 1.2e-21
HMBAKEGM_00992 1.6e-76 K LytTr DNA-binding domain
HMBAKEGM_00993 4.4e-61 S Protein of unknown function (DUF3021)
HMBAKEGM_00994 2.2e-78 XK27_09675 K Acetyltransferase (GNAT) domain
HMBAKEGM_00995 8.1e-137
HMBAKEGM_00996 3.3e-47
HMBAKEGM_00997 8.3e-23 K HxlR-like helix-turn-helix
HMBAKEGM_00998 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HMBAKEGM_00999 5.2e-192 V Beta-lactamase
HMBAKEGM_01000 3.1e-275 pepV 3.5.1.18 E dipeptidase PepV
HMBAKEGM_01001 6.6e-19 brnQ U Component of the transport system for branched-chain amino acids
HMBAKEGM_01002 1.8e-56
HMBAKEGM_01003 1.4e-89 malY 4.4.1.8 E Aminotransferase, class I
HMBAKEGM_01004 1.9e-57 malY 4.4.1.8 E Aminotransferase, class I
HMBAKEGM_01005 3e-37
HMBAKEGM_01006 2.1e-102 S LexA-binding, inner membrane-associated putative hydrolase
HMBAKEGM_01007 3.4e-22
HMBAKEGM_01008 1.1e-92 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMBAKEGM_01010 3.3e-10 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HMBAKEGM_01011 2.5e-247 N Uncharacterized conserved protein (DUF2075)
HMBAKEGM_01012 5.4e-213 mmuP E amino acid
HMBAKEGM_01013 2.8e-185 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HMBAKEGM_01014 1.2e-70 amd 3.5.1.47 E Peptidase family M20/M25/M40
HMBAKEGM_01015 8.7e-104 amd 3.5.1.47 E Peptidase family M20/M25/M40
HMBAKEGM_01016 5.6e-234 steT E amino acid
HMBAKEGM_01017 1.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HMBAKEGM_01018 0.0 pepO 3.4.24.71 O Peptidase family M13
HMBAKEGM_01019 4.2e-257 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMBAKEGM_01020 1.9e-102 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMBAKEGM_01021 4.6e-89 L PFAM transposase, IS4 family protein
HMBAKEGM_01022 5.7e-12 L PFAM transposase, IS4 family protein
HMBAKEGM_01023 0.0
HMBAKEGM_01024 0.0 S PglZ domain
HMBAKEGM_01025 6.5e-11 LO the current gene model (or a revised gene model) may contain a frame shift
HMBAKEGM_01026 0.0 2.1.1.72 LV Eco57I restriction-modification methylase
HMBAKEGM_01027 2.3e-216 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
HMBAKEGM_01028 1.4e-101 S Domain of unknown function (DUF1788)
HMBAKEGM_01029 5.9e-106 S Putative inner membrane protein (DUF1819)
HMBAKEGM_01030 1.3e-206 S Protein of unknown function DUF262
HMBAKEGM_01031 2.3e-30 S Protein of unknown function DUF262
HMBAKEGM_01033 6.5e-31 4.4.1.5 E lactoylglutathione lyase activity
HMBAKEGM_01034 1.5e-11 4.4.1.5 E lactoylglutathione lyase activity
HMBAKEGM_01035 1.6e-66 S ASCH domain
HMBAKEGM_01036 2.4e-109 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMBAKEGM_01037 4.7e-81
HMBAKEGM_01038 5.3e-308
HMBAKEGM_01039 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HMBAKEGM_01040 1.8e-130 treR K UTRA
HMBAKEGM_01041 0.0 treB G phosphotransferase system
HMBAKEGM_01042 4.6e-291 V ABC transporter transmembrane region
HMBAKEGM_01043 4.1e-289 lsa S ABC transporter
HMBAKEGM_01044 1.9e-74 S Protein of unknown function (DUF3021)
HMBAKEGM_01045 6.6e-75 K LytTr DNA-binding domain
HMBAKEGM_01046 8.8e-107 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
HMBAKEGM_01049 0.0 uvrA3 L excinuclease ABC, A subunit
HMBAKEGM_01050 2.1e-96 yyaR K Acetyltransferase (GNAT) domain
HMBAKEGM_01051 4e-62 mta K helix_turn_helix, mercury resistance
HMBAKEGM_01052 3.6e-15 mta K helix_turn_helix, mercury resistance
HMBAKEGM_01053 5.3e-07 S ParE toxin of type II toxin-antitoxin system, parDE
HMBAKEGM_01054 1.6e-60 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMBAKEGM_01055 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HMBAKEGM_01056 2.6e-83 S Domain of unknown function (DUF5067)
HMBAKEGM_01057 1.3e-63
HMBAKEGM_01059 4.3e-120 XK27_07525 3.6.1.55 F NUDIX domain
HMBAKEGM_01060 1.2e-143 2.4.2.3 F Phosphorylase superfamily
HMBAKEGM_01061 1.8e-65 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
HMBAKEGM_01063 1.3e-82 K Acetyltransferase (GNAT) domain
HMBAKEGM_01064 4.3e-56
HMBAKEGM_01065 9.8e-79
HMBAKEGM_01066 4.6e-38
HMBAKEGM_01067 6.1e-208 EGP Major facilitator Superfamily
HMBAKEGM_01068 2.9e-233 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMBAKEGM_01069 1.1e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMBAKEGM_01070 1.3e-168 xerC D Phage integrase, N-terminal SAM-like domain
HMBAKEGM_01071 1.9e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMBAKEGM_01072 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMBAKEGM_01073 4.3e-155 dprA LU DNA protecting protein DprA
HMBAKEGM_01074 2.9e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMBAKEGM_01075 7.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMBAKEGM_01076 9.3e-36 yozE S Belongs to the UPF0346 family
HMBAKEGM_01077 7.7e-149 DegV S Uncharacterised protein, DegV family COG1307
HMBAKEGM_01078 1.5e-113 hlyIII S protein, hemolysin III
HMBAKEGM_01079 3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMBAKEGM_01080 3.2e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMBAKEGM_01081 7.8e-230 S Tetratricopeptide repeat protein
HMBAKEGM_01082 3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMBAKEGM_01083 2.8e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMBAKEGM_01084 3.3e-209 rpsA 1.17.7.4 J Ribosomal protein S1
HMBAKEGM_01085 3.5e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMBAKEGM_01086 2.4e-30 M Lysin motif
HMBAKEGM_01087 2.4e-78 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMBAKEGM_01088 2.2e-21 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMBAKEGM_01089 1e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMBAKEGM_01090 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMBAKEGM_01091 2.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMBAKEGM_01092 4.9e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMBAKEGM_01093 4e-167 xerD D recombinase XerD
HMBAKEGM_01094 5e-170 cvfB S S1 domain
HMBAKEGM_01095 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMBAKEGM_01096 1.9e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMBAKEGM_01097 0.0 dnaE 2.7.7.7 L DNA polymerase
HMBAKEGM_01098 2.5e-22 S Protein of unknown function (DUF2929)
HMBAKEGM_01099 1.3e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMBAKEGM_01100 4.1e-26 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMBAKEGM_01101 6.2e-33 yrvD S Lipopolysaccharide assembly protein A domain
HMBAKEGM_01102 1.4e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMBAKEGM_01103 3.1e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMBAKEGM_01104 0.0 oatA I Acyltransferase
HMBAKEGM_01105 1.4e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMBAKEGM_01106 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMBAKEGM_01107 2.5e-71 L Transposase
HMBAKEGM_01108 3.5e-71 dedA 3.1.3.1 S SNARE associated Golgi protein
HMBAKEGM_01109 9.9e-250 yfnA E Amino Acid
HMBAKEGM_01110 3.3e-43 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMBAKEGM_01111 9.9e-78 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMBAKEGM_01112 1.1e-14 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMBAKEGM_01113 9.6e-46 yxeH S hydrolase
HMBAKEGM_01114 1.9e-84 yxeH S hydrolase
HMBAKEGM_01115 9.2e-158 S reductase
HMBAKEGM_01116 6e-219 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMBAKEGM_01117 2.1e-224 patA 2.6.1.1 E Aminotransferase
HMBAKEGM_01118 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMBAKEGM_01119 2.3e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMBAKEGM_01120 2.1e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMBAKEGM_01121 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMBAKEGM_01122 1.4e-59
HMBAKEGM_01123 4.8e-38 prmA J Ribosomal protein L11 methyltransferase
HMBAKEGM_01124 3.3e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMBAKEGM_01125 1.6e-96 yxkA S Phosphatidylethanolamine-binding protein
HMBAKEGM_01126 4e-248 yjjP S Putative threonine/serine exporter
HMBAKEGM_01127 2.4e-178 citR K Putative sugar-binding domain
HMBAKEGM_01128 1.6e-52
HMBAKEGM_01129 1.6e-16
HMBAKEGM_01130 6.4e-66 S Domain of unknown function DUF1828
HMBAKEGM_01131 8.1e-94 S UPF0397 protein
HMBAKEGM_01132 0.0 ykoD P ABC transporter, ATP-binding protein
HMBAKEGM_01133 4.3e-147 cbiQ P cobalt transport
HMBAKEGM_01134 2.7e-10
HMBAKEGM_01135 2.7e-71 yeaL S Protein of unknown function (DUF441)
HMBAKEGM_01136 1e-72 L Transposase
HMBAKEGM_01137 6.9e-150
HMBAKEGM_01138 9.2e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HMBAKEGM_01139 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HMBAKEGM_01140 9.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
HMBAKEGM_01141 5.7e-197 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HMBAKEGM_01142 4e-155 ydjP I Alpha/beta hydrolase family
HMBAKEGM_01143 9.4e-275 P Sodium:sulfate symporter transmembrane region
HMBAKEGM_01144 1.9e-258 pepC 3.4.22.40 E Peptidase C1-like family
HMBAKEGM_01145 9.3e-29
HMBAKEGM_01147 4.7e-20
HMBAKEGM_01148 1.5e-12
HMBAKEGM_01149 3.7e-74 fhaB M Rib/alpha-like repeat
HMBAKEGM_01150 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMBAKEGM_01151 2.6e-78 UW LPXTG-motif cell wall anchor domain protein
HMBAKEGM_01152 2.2e-56 UW LPXTG-motif cell wall anchor domain protein
HMBAKEGM_01153 1.4e-68 UW LPXTG-motif cell wall anchor domain protein
HMBAKEGM_01154 7.4e-15 S YSIRK type signal peptide
HMBAKEGM_01155 6.2e-13 M domain protein
HMBAKEGM_01156 6.3e-08 M domain protein
HMBAKEGM_01157 1.5e-57 M domain protein
HMBAKEGM_01159 1e-262 frdC 1.3.5.4 C FAD binding domain
HMBAKEGM_01160 8.6e-240 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMBAKEGM_01161 5.5e-16 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMBAKEGM_01162 1.7e-34
HMBAKEGM_01163 1.7e-65 S cog cog1373
HMBAKEGM_01164 1.3e-76 S cog cog1373
HMBAKEGM_01165 6.4e-88 metI P ABC transporter permease
HMBAKEGM_01166 3.6e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMBAKEGM_01167 2.8e-162 metQ1 P Belongs to the nlpA lipoprotein family
HMBAKEGM_01168 0.0 aha1 P E1-E2 ATPase
HMBAKEGM_01169 1.2e-14 ps301 K sequence-specific DNA binding
HMBAKEGM_01170 7.2e-16 ps301 K sequence-specific DNA binding
HMBAKEGM_01171 8.1e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMBAKEGM_01172 6.7e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMBAKEGM_01174 3.3e-116 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMBAKEGM_01175 2.4e-24 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMBAKEGM_01176 2.3e-99 3.6.1.27 I Acid phosphatase homologues
HMBAKEGM_01177 1.5e-114 yitS S Uncharacterised protein, DegV family COG1307
HMBAKEGM_01178 4.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMBAKEGM_01179 7.5e-69 S Domain of unknown function (DUF4767)
HMBAKEGM_01180 1.2e-85 C nitroreductase
HMBAKEGM_01181 7.7e-11 ypbG 2.7.1.2 GK ROK family
HMBAKEGM_01182 7.7e-80 ypbG 2.7.1.2 GK ROK family
HMBAKEGM_01183 9.7e-282 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMBAKEGM_01184 1.1e-135 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMBAKEGM_01185 9.1e-61 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMBAKEGM_01186 5.5e-135 gmuR K UTRA
HMBAKEGM_01187 1.4e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
HMBAKEGM_01188 1.2e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMBAKEGM_01189 7.5e-108 pncA Q Isochorismatase family
HMBAKEGM_01190 1.2e-98 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HMBAKEGM_01191 1.9e-96 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HMBAKEGM_01193 4.1e-118 K UTRA domain
HMBAKEGM_01194 1.8e-59 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMBAKEGM_01195 3.6e-182 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMBAKEGM_01196 9.8e-18 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMBAKEGM_01197 1.5e-174 S Aldo keto reductase
HMBAKEGM_01198 2e-177 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HMBAKEGM_01199 1e-82
HMBAKEGM_01200 3e-17 C FMN_bind
HMBAKEGM_01201 4.5e-302 I Protein of unknown function (DUF2974)
HMBAKEGM_01202 3.2e-106 3.6.1.55 F NUDIX domain
HMBAKEGM_01203 1.8e-206 pbpX1 V Beta-lactamase
HMBAKEGM_01204 1.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMBAKEGM_01205 7.1e-217 aspC 2.6.1.1 E Aminotransferase
HMBAKEGM_01206 2.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMBAKEGM_01207 2.2e-176 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMBAKEGM_01208 2e-191 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMBAKEGM_01209 3.6e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMBAKEGM_01210 1.7e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMBAKEGM_01211 7.9e-70 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMBAKEGM_01212 4.2e-197 pbpX1 V Beta-lactamase
HMBAKEGM_01213 4.8e-38 L Helicase C-terminal domain protein
HMBAKEGM_01214 2.9e-88 E amino acid
HMBAKEGM_01215 1.6e-44 E amino acid
HMBAKEGM_01216 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
HMBAKEGM_01217 1.4e-169 yniA G Phosphotransferase enzyme family
HMBAKEGM_01218 6.9e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMBAKEGM_01219 6.3e-48 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HMBAKEGM_01220 1.9e-92 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HMBAKEGM_01221 1.6e-290 tetP J elongation factor G
HMBAKEGM_01222 2.8e-68 tetP J elongation factor G
HMBAKEGM_01223 4.7e-165 yvgN C Aldo keto reductase
HMBAKEGM_01224 2.5e-109 S SLAP domain
HMBAKEGM_01225 1.1e-59 S SLAP domain
HMBAKEGM_01226 2.3e-74 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMBAKEGM_01227 4e-46 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMBAKEGM_01228 1.6e-177 ABC-SBP S ABC transporter
HMBAKEGM_01229 1.2e-115 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HMBAKEGM_01230 9.6e-138 XK27_08845 S ABC transporter, ATP-binding protein
HMBAKEGM_01231 4.1e-41
HMBAKEGM_01232 4.8e-11
HMBAKEGM_01233 6.2e-105 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HMBAKEGM_01234 2.2e-177 K AI-2E family transporter
HMBAKEGM_01235 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HMBAKEGM_01236 2.1e-67 S Domain of unknown function (DUF4430)
HMBAKEGM_01237 1.4e-87 S ECF transporter, substrate-specific component
HMBAKEGM_01238 1.3e-99 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HMBAKEGM_01239 1.6e-148 S Putative ABC-transporter type IV
HMBAKEGM_01240 4e-235 S LPXTG cell wall anchor motif
HMBAKEGM_01241 1.4e-29 pipD E Dipeptidase
HMBAKEGM_01242 1.5e-77 pipD E Dipeptidase
HMBAKEGM_01243 4.5e-30 pipD E Dipeptidase
HMBAKEGM_01244 1.1e-183 V Restriction endonuclease
HMBAKEGM_01245 1.6e-41 K Bacterial regulatory proteins, tetR family
HMBAKEGM_01246 2.2e-54 K Bacterial regulatory proteins, tetR family
HMBAKEGM_01247 3e-23 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMBAKEGM_01248 8.4e-131 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMBAKEGM_01249 3e-131 ybbM S Uncharacterised protein family (UPF0014)
HMBAKEGM_01250 1.4e-113 ybbL S ABC transporter, ATP-binding protein
HMBAKEGM_01251 3.9e-30 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HMBAKEGM_01253 2e-33
HMBAKEGM_01256 1.2e-163 L Belongs to the 'phage' integrase family
HMBAKEGM_01257 1.6e-27
HMBAKEGM_01258 2.6e-59
HMBAKEGM_01259 1.4e-155 S Replication initiation factor
HMBAKEGM_01260 1.6e-148 D Ftsk spoiiie family protein
HMBAKEGM_01261 2.3e-104
HMBAKEGM_01262 2.6e-74
HMBAKEGM_01263 7.9e-140 K Helix-turn-helix XRE-family like proteins
HMBAKEGM_01265 1.2e-121 yhiD S MgtC family
HMBAKEGM_01266 5.7e-241 I Protein of unknown function (DUF2974)
HMBAKEGM_01267 1.1e-35
HMBAKEGM_01269 3.8e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HMBAKEGM_01270 8.3e-176 degV S DegV family
HMBAKEGM_01271 2.6e-169 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HMBAKEGM_01272 1.2e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMBAKEGM_01273 4.3e-69 rplI J Binds to the 23S rRNA
HMBAKEGM_01274 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMBAKEGM_01276 0.0 KLT Protein kinase domain
HMBAKEGM_01277 3.7e-42 KLT serine threonine protein kinase
HMBAKEGM_01278 1.9e-175 V ABC transporter transmembrane region
HMBAKEGM_01279 1.9e-33 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMBAKEGM_01280 2.6e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMBAKEGM_01281 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HMBAKEGM_01282 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMBAKEGM_01283 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMBAKEGM_01284 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMBAKEGM_01285 1.3e-34 yaaA S S4 domain protein YaaA
HMBAKEGM_01286 3.9e-196 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMBAKEGM_01287 5.7e-259 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMBAKEGM_01288 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HMBAKEGM_01289 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMBAKEGM_01290 6.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMBAKEGM_01291 5.6e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMBAKEGM_01292 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMBAKEGM_01293 2.2e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMBAKEGM_01294 8.4e-290 clcA P chloride
HMBAKEGM_01295 1.7e-212
HMBAKEGM_01296 1.2e-18
HMBAKEGM_01297 1.9e-207 EGP Sugar (and other) transporter
HMBAKEGM_01298 0.0 copA 3.6.3.54 P P-type ATPase
HMBAKEGM_01299 1.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMBAKEGM_01300 1.2e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMBAKEGM_01301 1e-75 atkY K Penicillinase repressor
HMBAKEGM_01302 6.7e-35
HMBAKEGM_01303 1.5e-223 pbuG S permease
HMBAKEGM_01304 2.1e-241 amtB P ammonium transporter
HMBAKEGM_01305 1.2e-231 pbuG S permease
HMBAKEGM_01306 4e-133 K helix_turn_helix, mercury resistance
HMBAKEGM_01307 2.2e-174 S cog cog1373
HMBAKEGM_01308 2.4e-218 pbuG S permease
HMBAKEGM_01309 1.6e-146 cof S haloacid dehalogenase-like hydrolase
HMBAKEGM_01310 1.4e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HMBAKEGM_01311 5.5e-118 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HMBAKEGM_01313 2.8e-20 ybbH_2 K rpiR family
HMBAKEGM_01314 1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMBAKEGM_01315 5.2e-161 yeaE S Aldo/keto reductase family
HMBAKEGM_01316 4.3e-96 S ECF transporter, substrate-specific component
HMBAKEGM_01317 0.0 macB_3 V ABC transporter, ATP-binding protein
HMBAKEGM_01318 5.2e-41 macB_3 V ABC transporter, ATP-binding protein
HMBAKEGM_01319 1.2e-12 macB_3 V ABC transporter, ATP-binding protein
HMBAKEGM_01320 2.9e-196 S DUF218 domain
HMBAKEGM_01321 4.6e-120 S CAAX protease self-immunity
HMBAKEGM_01322 6.4e-47
HMBAKEGM_01323 5.9e-160 mutR K Helix-turn-helix XRE-family like proteins
HMBAKEGM_01324 4e-81 S Putative adhesin
HMBAKEGM_01325 9.3e-284 V ABC transporter transmembrane region
HMBAKEGM_01326 4.7e-47 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HMBAKEGM_01327 1.5e-49 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HMBAKEGM_01328 1.3e-205 napA P Sodium/hydrogen exchanger family
HMBAKEGM_01329 0.0 cadA P P-type ATPase
HMBAKEGM_01330 2.6e-216 ywhK S Membrane
HMBAKEGM_01331 2.2e-50
HMBAKEGM_01332 2.4e-19 S D-Ala-teichoic acid biosynthesis protein
HMBAKEGM_01333 2.5e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMBAKEGM_01334 3e-242 dltB M MBOAT, membrane-bound O-acyltransferase family
HMBAKEGM_01335 5.7e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMBAKEGM_01336 3.5e-249 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMBAKEGM_01337 3.2e-175 pbpX2 V Beta-lactamase
HMBAKEGM_01339 5.9e-10
HMBAKEGM_01340 4.1e-127 S CAAX protease self-immunity
HMBAKEGM_01341 4.9e-29
HMBAKEGM_01342 1.9e-50
HMBAKEGM_01343 1.2e-18
HMBAKEGM_01345 2.2e-125 S Protein of unknown function (DUF975)
HMBAKEGM_01346 3.6e-146 lysA2 M Glycosyl hydrolases family 25
HMBAKEGM_01347 3.3e-289 ytgP S Polysaccharide biosynthesis protein
HMBAKEGM_01348 1.1e-36
HMBAKEGM_01349 1.1e-228 XK27_06780 V ABC transporter permease
HMBAKEGM_01350 1.3e-113 XK27_06780 V ABC transporter permease
HMBAKEGM_01351 5.2e-136 XK27_06785 V ABC transporter, ATP-binding protein
HMBAKEGM_01352 1.3e-227 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMBAKEGM_01353 7.2e-172 S Alpha/beta hydrolase of unknown function (DUF915)
HMBAKEGM_01354 0.0 clpE O AAA domain (Cdc48 subfamily)
HMBAKEGM_01355 4.9e-119 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMBAKEGM_01356 8.7e-131
HMBAKEGM_01357 3e-222 cycA E Amino acid permease
HMBAKEGM_01358 1.6e-247 yifK E Amino acid permease
HMBAKEGM_01359 1.5e-14 puuD S peptidase C26
HMBAKEGM_01360 1e-95 steT_1 E amino acid
HMBAKEGM_01361 2.7e-26
HMBAKEGM_01362 4.6e-121
HMBAKEGM_01363 6.9e-130 ecfA P ABC-type multidrug transport system ATPase component
HMBAKEGM_01364 4.3e-194 asnA 6.3.1.1 F aspartate--ammonia ligase
HMBAKEGM_01365 4.8e-204 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HMBAKEGM_01368 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMBAKEGM_01369 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMBAKEGM_01370 8.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMBAKEGM_01371 2.1e-58
HMBAKEGM_01372 2.8e-87
HMBAKEGM_01373 2.2e-74 yheS_2 S ATPases associated with a variety of cellular activities
HMBAKEGM_01374 2.7e-71 yheS_2 S ATPases associated with a variety of cellular activities
HMBAKEGM_01376 2.1e-177 XK27_05540 S DUF218 domain
HMBAKEGM_01377 6e-80
HMBAKEGM_01378 1.1e-110
HMBAKEGM_01379 4.4e-138 EG EamA-like transporter family
HMBAKEGM_01380 1.5e-43 M NlpC P60 family
HMBAKEGM_01381 1.9e-132 cobQ S glutamine amidotransferase
HMBAKEGM_01383 4.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMBAKEGM_01384 2.2e-82 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMBAKEGM_01385 6.8e-90 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMBAKEGM_01386 1.8e-51 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMBAKEGM_01387 2.1e-148 ptp2 3.1.3.48 T Tyrosine phosphatase family
HMBAKEGM_01388 9.7e-180 yvdE K helix_turn _helix lactose operon repressor
HMBAKEGM_01389 2.9e-46 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMBAKEGM_01390 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HMBAKEGM_01391 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HMBAKEGM_01392 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HMBAKEGM_01393 2e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HMBAKEGM_01394 8e-210 msmX P Belongs to the ABC transporter superfamily
HMBAKEGM_01395 2.5e-212 malE G Bacterial extracellular solute-binding protein
HMBAKEGM_01396 7.9e-252 malF P Binding-protein-dependent transport system inner membrane component
HMBAKEGM_01397 4.1e-153 malG P ABC transporter permease
HMBAKEGM_01398 3e-36 atl 3.2.1.96, 3.5.1.28 GH73 M domain, Protein
HMBAKEGM_01399 8.8e-98 atl 3.2.1.96, 3.5.1.28 GH73 M domain, Protein
HMBAKEGM_01400 7.9e-54 3.2.1.4 GH5,GH9 M domain protein
HMBAKEGM_01401 1.3e-23 L 4.5 Transposon and IS
HMBAKEGM_01402 3e-23 K DeoR C terminal sensor domain
HMBAKEGM_01403 3.7e-94
HMBAKEGM_01404 1.9e-23 S Small integral membrane protein (DUF2273)
HMBAKEGM_01405 1.4e-87 S Asp23 family, cell envelope-related function
HMBAKEGM_01406 1.3e-11 S Transglycosylase associated protein
HMBAKEGM_01407 1.3e-16
HMBAKEGM_01409 1.5e-71 L Transposase and inactivated derivatives, IS30 family
HMBAKEGM_01410 1.7e-32 M NlpC/P60 family
HMBAKEGM_01411 3.1e-91 2.7.7.65 T phosphorelay sensor kinase activity
HMBAKEGM_01412 3.9e-134 cbiQ P Cobalt transport protein
HMBAKEGM_01413 7e-158 P ABC transporter
HMBAKEGM_01414 1.2e-151 cbiO2 P ABC transporter
HMBAKEGM_01415 1.4e-58 L Psort location Cytoplasmic, score
HMBAKEGM_01416 6.7e-259 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HMBAKEGM_01417 4e-33 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMBAKEGM_01418 1.9e-53 eutP E Ethanolamine utilisation - propanediol utilisation
HMBAKEGM_01419 7.3e-44 U FFAT motif binding
HMBAKEGM_01420 8.8e-85 U FFAT motif binding
HMBAKEGM_01421 8.7e-125 S ECF-type riboflavin transporter, S component
HMBAKEGM_01422 0.0 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
HMBAKEGM_01423 1.2e-155 P ABC-type cobalt transport system permease component CbiQ and related transporters
HMBAKEGM_01425 2.6e-97 S Uncharacterised protein family (UPF0236)
HMBAKEGM_01426 2.1e-111 S Domain of unknown function (DUF4430)
HMBAKEGM_01427 2.7e-183 U FFAT motif binding
HMBAKEGM_01428 5.3e-80 S Domain of unknown function (DUF4430)
HMBAKEGM_01429 1.5e-15 NU Mycoplasma protein of unknown function, DUF285
HMBAKEGM_01430 6.7e-234 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMBAKEGM_01431 4.7e-96 ywnH 2.3.1.183 M acetyltransferase (GNAT) family
HMBAKEGM_01432 2.2e-15 K Penicillinase repressor
HMBAKEGM_01433 0.0 copB 3.6.3.4 P P-type ATPase
HMBAKEGM_01434 2.7e-39 mdt(A) EGP Major facilitator Superfamily
HMBAKEGM_01435 1.7e-66 mdt(A) EGP Major facilitator Superfamily
HMBAKEGM_01436 1.3e-157 glcU U sugar transport
HMBAKEGM_01437 5.1e-63 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMBAKEGM_01438 1e-129 L Transposase
HMBAKEGM_01439 5.8e-103 L Resolvase, N terminal domain
HMBAKEGM_01440 1.8e-13 ytgB S Transglycosylase associated protein
HMBAKEGM_01441 1e-188 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HMBAKEGM_01442 3.8e-78 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMBAKEGM_01443 9.6e-80 marR K Transcriptional regulator
HMBAKEGM_01444 4.5e-180 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMBAKEGM_01445 1.4e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMBAKEGM_01446 1.5e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HMBAKEGM_01447 1.7e-128 IQ reductase
HMBAKEGM_01448 1.6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMBAKEGM_01449 2.1e-79 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMBAKEGM_01450 2.7e-73 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HMBAKEGM_01451 2.5e-261 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HMBAKEGM_01452 2.7e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMBAKEGM_01453 4.1e-144 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HMBAKEGM_01454 1.3e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HMBAKEGM_01455 1.8e-189 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMBAKEGM_01456 6.3e-91 bioY S BioY family
HMBAKEGM_01457 8e-48
HMBAKEGM_01458 2.3e-96 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HMBAKEGM_01459 4.3e-184 P secondary active sulfate transmembrane transporter activity
HMBAKEGM_01460 1.3e-108 L Transposase and inactivated derivatives, IS30 family
HMBAKEGM_01461 2.4e-124 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
HMBAKEGM_01462 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMBAKEGM_01463 5.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMBAKEGM_01464 4.6e-42 L Psort location Cytoplasmic, score
HMBAKEGM_01465 3.9e-135 L Psort location Cytoplasmic, score
HMBAKEGM_01466 2.8e-84 FG adenosine 5'-monophosphoramidase activity
HMBAKEGM_01467 7.2e-47
HMBAKEGM_01468 2.8e-100 L Integrase
HMBAKEGM_01469 8e-42 S RelB antitoxin
HMBAKEGM_01470 2.1e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMBAKEGM_01474 7.9e-188 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
HMBAKEGM_01476 5.1e-274 V ABC-type multidrug transport system, ATPase and permease components
HMBAKEGM_01477 2.6e-286 V ABC-type multidrug transport system, ATPase and permease components
HMBAKEGM_01478 5.1e-63 K LysR substrate binding domain
HMBAKEGM_01479 1e-07 K LysR substrate binding domain
HMBAKEGM_01480 1.3e-34 S Cytochrome b5
HMBAKEGM_01481 1.1e-166 arbZ I Phosphate acyltransferases
HMBAKEGM_01482 4.5e-151 arbY M Glycosyl transferase family 8
HMBAKEGM_01483 3.7e-10 arbY M Glycosyl transferase family 8
HMBAKEGM_01484 1.8e-186 arbY M Glycosyl transferase family 8
HMBAKEGM_01485 4.1e-158 arbx M Glycosyl transferase family 8
HMBAKEGM_01486 2.4e-41 K Helix-turn-helix domain
HMBAKEGM_01487 1.3e-87 K Helix-turn-helix domain
HMBAKEGM_01488 1.9e-14
HMBAKEGM_01489 5e-66
HMBAKEGM_01490 5.6e-146 arbV 2.3.1.51 I Acyl-transferase
HMBAKEGM_01491 2.5e-195 S SLAP domain
HMBAKEGM_01492 3.9e-18
HMBAKEGM_01493 2e-166 S SLAP domain
HMBAKEGM_01494 6.7e-11 L Transposase
HMBAKEGM_01496 2.4e-33
HMBAKEGM_01498 4.8e-308 vicK 2.7.13.3 T Histidine kinase
HMBAKEGM_01499 3.5e-244 yycH S YycH protein
HMBAKEGM_01500 6.9e-150 yycI S YycH protein
HMBAKEGM_01501 3.3e-149 vicX 3.1.26.11 S domain protein
HMBAKEGM_01502 1.5e-180 htrA 3.4.21.107 O serine protease
HMBAKEGM_01503 1.6e-90 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMBAKEGM_01504 2.7e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HMBAKEGM_01505 1.4e-92 P Cobalt transport protein
HMBAKEGM_01506 1.9e-250 cbiO1 S ABC transporter, ATP-binding protein
HMBAKEGM_01507 5.1e-173 K helix_turn_helix, arabinose operon control protein
HMBAKEGM_01508 4.1e-59 L hmm pf00665
HMBAKEGM_01509 5.6e-08 L hmm pf00665
HMBAKEGM_01510 1.8e-19 L hmm pf00665
HMBAKEGM_01511 1.8e-65 L Helix-turn-helix domain
HMBAKEGM_01512 1.3e-162 htpX O Belongs to the peptidase M48B family
HMBAKEGM_01513 2.3e-96 lemA S LemA family
HMBAKEGM_01514 1.4e-185 ybiR P Citrate transporter
HMBAKEGM_01515 5.9e-70 S Iron-sulphur cluster biosynthesis
HMBAKEGM_01516 4.2e-19 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HMBAKEGM_01517 1.2e-17
HMBAKEGM_01518 1e-151
HMBAKEGM_01519 2.7e-20 G Glycosyl hydrolases family 8
HMBAKEGM_01520 4.4e-64 G Glycosyl hydrolases family 8
HMBAKEGM_01521 4.7e-17 S Peptidase propeptide and YPEB domain
HMBAKEGM_01523 2.2e-122 yfbR S HD containing hydrolase-like enzyme
HMBAKEGM_01524 2.4e-161 L HNH nucleases
HMBAKEGM_01525 3.3e-138 glnQ E ABC transporter, ATP-binding protein
HMBAKEGM_01526 2.9e-293 glnP P ABC transporter permease
HMBAKEGM_01527 4.5e-54 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HMBAKEGM_01528 6.7e-27 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HMBAKEGM_01529 8.2e-63 yeaO S Protein of unknown function, DUF488
HMBAKEGM_01530 3.8e-121 terC P Integral membrane protein TerC family
HMBAKEGM_01531 4.4e-94 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HMBAKEGM_01532 4.3e-132 cobB K SIR2 family
HMBAKEGM_01533 1e-84
HMBAKEGM_01534 1.2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMBAKEGM_01535 1e-178 S Alpha/beta hydrolase of unknown function (DUF915)
HMBAKEGM_01536 5.6e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMBAKEGM_01537 1.1e-140 ypuA S Protein of unknown function (DUF1002)
HMBAKEGM_01538 3.4e-149 epsV 2.7.8.12 S glycosyl transferase family 2
HMBAKEGM_01539 3.3e-126 S Alpha/beta hydrolase family
HMBAKEGM_01540 7.8e-117 GM NmrA-like family
HMBAKEGM_01541 4.7e-65
HMBAKEGM_01542 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMBAKEGM_01543 1.7e-122 luxT K Bacterial regulatory proteins, tetR family
HMBAKEGM_01544 1e-129
HMBAKEGM_01545 2.9e-263 glnPH2 P ABC transporter permease
HMBAKEGM_01546 8.1e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMBAKEGM_01547 2.2e-232 S Cysteine-rich secretory protein family
HMBAKEGM_01548 4.7e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMBAKEGM_01549 7.2e-67
HMBAKEGM_01550 8.2e-202 yibE S overlaps another CDS with the same product name
HMBAKEGM_01551 1.2e-130 yibF S overlaps another CDS with the same product name
HMBAKEGM_01552 1.9e-160 I alpha/beta hydrolase fold
HMBAKEGM_01553 5.7e-29
HMBAKEGM_01554 0.0 G Belongs to the glycosyl hydrolase 31 family
HMBAKEGM_01555 5.7e-80 ntd 2.4.2.6 F Nucleoside
HMBAKEGM_01556 4.9e-90 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMBAKEGM_01557 9.8e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HMBAKEGM_01558 8.5e-87 uspA T universal stress protein
HMBAKEGM_01559 9.9e-153 phnD P Phosphonate ABC transporter
HMBAKEGM_01560 5.2e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HMBAKEGM_01561 9.1e-131 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HMBAKEGM_01562 1.2e-149 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HMBAKEGM_01563 2e-108 tag 3.2.2.20 L glycosylase
HMBAKEGM_01564 8.7e-84
HMBAKEGM_01565 1.3e-273 S Calcineurin-like phosphoesterase
HMBAKEGM_01566 0.0 asnB 6.3.5.4 E Asparagine synthase
HMBAKEGM_01567 9.5e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
HMBAKEGM_01569 3.6e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
HMBAKEGM_01570 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMBAKEGM_01571 4.3e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMBAKEGM_01572 7e-101 S Iron-sulfur cluster assembly protein
HMBAKEGM_01573 6.1e-232 XK27_04775 S PAS domain
HMBAKEGM_01574 2.1e-227 yttB EGP Major facilitator Superfamily
HMBAKEGM_01575 0.0 pepO 3.4.24.71 O Peptidase family M13
HMBAKEGM_01576 0.0 kup P Transport of potassium into the cell
HMBAKEGM_01577 6.6e-75
HMBAKEGM_01579 6.7e-28
HMBAKEGM_01580 1.4e-16 S Protein of unknown function (DUF2922)
HMBAKEGM_01581 6.5e-180 S SLAP domain
HMBAKEGM_01583 1.7e-38
HMBAKEGM_01584 8e-211 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMBAKEGM_01585 2.5e-208 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HMBAKEGM_01586 2.2e-83 yjbQ P TrkA C-terminal domain protein
HMBAKEGM_01589 1.9e-96 tnpR L Resolvase, N terminal domain
HMBAKEGM_01590 3.3e-132
HMBAKEGM_01591 1.8e-156 yjbQ P TrkA C-terminal domain protein
HMBAKEGM_01592 2.4e-116 gepA K Protein of unknown function (DUF4065)
HMBAKEGM_01593 7.5e-180 S Oxidoreductase family, NAD-binding Rossmann fold
HMBAKEGM_01594 4.4e-46
HMBAKEGM_01595 2.6e-135
HMBAKEGM_01596 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMBAKEGM_01597 2.2e-81 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMBAKEGM_01598 5.3e-101 G Aldose 1-epimerase
HMBAKEGM_01599 1.5e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMBAKEGM_01600 1.5e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMBAKEGM_01601 0.0 XK27_08315 M Sulfatase
HMBAKEGM_01602 4.8e-51 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMBAKEGM_01603 3.3e-269 S Fibronectin type III domain
HMBAKEGM_01604 1.1e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMBAKEGM_01605 2.6e-53
HMBAKEGM_01607 4.2e-258 pepC 3.4.22.40 E aminopeptidase
HMBAKEGM_01608 2.3e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMBAKEGM_01609 8.5e-301 oppA E ABC transporter, substratebinding protein
HMBAKEGM_01610 1e-306 oppA E ABC transporter, substratebinding protein
HMBAKEGM_01611 3.4e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMBAKEGM_01612 2.9e-144 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMBAKEGM_01613 4.9e-185 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMBAKEGM_01614 3.2e-200 oppD P Belongs to the ABC transporter superfamily
HMBAKEGM_01615 3.2e-175 oppF P Belongs to the ABC transporter superfamily
HMBAKEGM_01616 1.8e-256 pepC 3.4.22.40 E aminopeptidase
HMBAKEGM_01617 4.7e-60 hsp O Belongs to the small heat shock protein (HSP20) family
HMBAKEGM_01618 4.7e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMBAKEGM_01619 6.4e-114
HMBAKEGM_01621 5.3e-115 E Belongs to the SOS response-associated peptidase family
HMBAKEGM_01622 2.8e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMBAKEGM_01623 1.5e-91 comEB 3.5.4.12 F MafB19-like deaminase
HMBAKEGM_01624 1.3e-106 S TPM domain
HMBAKEGM_01625 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMBAKEGM_01626 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMBAKEGM_01627 4.6e-148 tatD L hydrolase, TatD family
HMBAKEGM_01628 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMBAKEGM_01629 2.3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMBAKEGM_01630 1e-38 veg S Biofilm formation stimulator VEG
HMBAKEGM_01631 2.4e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HMBAKEGM_01632 4.2e-208 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMBAKEGM_01633 1.6e-89 S SLAP domain
HMBAKEGM_01634 1.4e-87 S SLAP domain
HMBAKEGM_01635 3e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMBAKEGM_01636 1.6e-55 2.7.1.2 GK ROK family
HMBAKEGM_01637 1.6e-37 GK ROK family
HMBAKEGM_01638 1.8e-23
HMBAKEGM_01639 1.2e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMBAKEGM_01640 5.5e-68 S Domain of unknown function (DUF1934)
HMBAKEGM_01641 3.3e-55 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMBAKEGM_01642 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMBAKEGM_01643 3.6e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMBAKEGM_01644 4.6e-32 S Haloacid dehalogenase-like hydrolase
HMBAKEGM_01645 2.3e-57 S Haloacid dehalogenase-like hydrolase
HMBAKEGM_01646 4.1e-283 pipD E Dipeptidase
HMBAKEGM_01647 1.1e-158 msmR K AraC-like ligand binding domain
HMBAKEGM_01648 1.4e-212 pbuX F xanthine permease
HMBAKEGM_01649 7.4e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMBAKEGM_01650 1.6e-106 K DNA-binding helix-turn-helix protein
HMBAKEGM_01653 4e-19 K Helix-turn-helix
HMBAKEGM_01654 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMBAKEGM_01656 3.2e-15
HMBAKEGM_01658 8.9e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMBAKEGM_01659 2.6e-119 repA S Replication initiator protein A
HMBAKEGM_01660 8e-28
HMBAKEGM_01661 2e-125 S Fic/DOC family
HMBAKEGM_01662 8.9e-41
HMBAKEGM_01663 1.4e-25
HMBAKEGM_01664 0.0 traA L MobA MobL family protein
HMBAKEGM_01665 5.8e-49
HMBAKEGM_01666 9.6e-104
HMBAKEGM_01667 5.1e-51 S Cag pathogenicity island, type IV secretory system
HMBAKEGM_01668 9.8e-32
HMBAKEGM_01669 9.6e-118
HMBAKEGM_01670 0.0 traE U Psort location Cytoplasmic, score
HMBAKEGM_01671 1.3e-217 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
HMBAKEGM_01672 3.9e-207 M CHAP domain
HMBAKEGM_01673 4.8e-87
HMBAKEGM_01674 1.4e-63 CO COG0526, thiol-disulfide isomerase and thioredoxins
HMBAKEGM_01675 1.6e-79
HMBAKEGM_01677 1.5e-259 traK U COG3505 Type IV secretory pathway, VirD4 components
HMBAKEGM_01678 3.3e-59
HMBAKEGM_01679 1.9e-150
HMBAKEGM_01680 5.4e-66
HMBAKEGM_01681 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMBAKEGM_01682 6.9e-33
HMBAKEGM_01683 9.3e-198 L Psort location Cytoplasmic, score
HMBAKEGM_01684 8.3e-228 nhaC C Na H antiporter NhaC
HMBAKEGM_01685 6.3e-175 cycA E Amino acid permease
HMBAKEGM_01686 6.1e-41 cycA E Amino acid permease
HMBAKEGM_01687 5.2e-83 3.1.21.3 V Type I restriction modification DNA specificity domain
HMBAKEGM_01688 2.5e-305 hsdM 2.1.1.72 V type I restriction-modification system
HMBAKEGM_01689 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HMBAKEGM_01690 9e-45 3.6.4.12 L UvrD/REP helicase N-terminal domain
HMBAKEGM_01691 2.7e-20 3.6.4.12 L UvrD/REP helicase N-terminal domain
HMBAKEGM_01692 4.7e-131 L AAA ATPase domain
HMBAKEGM_01693 2.4e-60
HMBAKEGM_01694 8.9e-53
HMBAKEGM_01695 4.6e-249 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HMBAKEGM_01696 1.2e-75
HMBAKEGM_01697 1.2e-42 K Helix-turn-helix XRE-family like proteins
HMBAKEGM_01698 2.9e-303 S DNA primase
HMBAKEGM_01700 2.9e-122 S SLAP domain
HMBAKEGM_01701 3.2e-194 S Bacteriocin helveticin-J
HMBAKEGM_01702 2.7e-49
HMBAKEGM_01703 1.1e-62 ps115 K Helix-turn-helix XRE-family like proteins
HMBAKEGM_01704 3e-32 E Zn peptidase
HMBAKEGM_01706 9.2e-210 EGP Major facilitator Superfamily
HMBAKEGM_01707 2.9e-106 ropB K Transcriptional regulator
HMBAKEGM_01708 1e-193 O Heat shock 70 kDa protein
HMBAKEGM_01709 7.2e-43
HMBAKEGM_01710 1.2e-24 L Transposase
HMBAKEGM_01711 1e-159
HMBAKEGM_01712 7e-186 S Bacteriocin helveticin-J
HMBAKEGM_01713 1.3e-185 S SLAP domain
HMBAKEGM_01714 9.1e-158 S Sucrose-6F-phosphate phosphohydrolase
HMBAKEGM_01715 1.9e-39 rpmE2 J Ribosomal protein L31
HMBAKEGM_01716 5.3e-264 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMBAKEGM_01717 1.9e-254 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMBAKEGM_01718 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMBAKEGM_01719 1.5e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMBAKEGM_01720 2.8e-91 K transcriptional regulator
HMBAKEGM_01721 8.4e-128 S (CBS) domain
HMBAKEGM_01722 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMBAKEGM_01723 1.7e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMBAKEGM_01724 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMBAKEGM_01725 1.8e-34 yabO J S4 domain protein
HMBAKEGM_01726 9.8e-59 divIC D Septum formation initiator
HMBAKEGM_01727 4.1e-62 yabR J S1 RNA binding domain
HMBAKEGM_01728 5.8e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMBAKEGM_01729 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMBAKEGM_01730 3.1e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMBAKEGM_01731 2.1e-196 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMBAKEGM_01732 2.4e-300 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMBAKEGM_01734 7.6e-80
HMBAKEGM_01735 1.6e-08
HMBAKEGM_01737 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
HMBAKEGM_01738 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMBAKEGM_01739 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMBAKEGM_01740 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMBAKEGM_01741 3.9e-122 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HMBAKEGM_01742 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMBAKEGM_01743 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMBAKEGM_01744 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMBAKEGM_01745 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HMBAKEGM_01746 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMBAKEGM_01747 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HMBAKEGM_01748 4.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMBAKEGM_01749 1.2e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMBAKEGM_01750 4.2e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMBAKEGM_01751 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMBAKEGM_01752 2e-110 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMBAKEGM_01753 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMBAKEGM_01754 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HMBAKEGM_01755 1.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMBAKEGM_01756 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMBAKEGM_01757 4.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMBAKEGM_01758 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMBAKEGM_01759 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMBAKEGM_01760 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMBAKEGM_01761 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMBAKEGM_01762 2.2e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMBAKEGM_01763 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMBAKEGM_01764 2.3e-24 rpmD J Ribosomal protein L30
HMBAKEGM_01765 1.5e-71 rplO J Binds to the 23S rRNA
HMBAKEGM_01766 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMBAKEGM_01767 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMBAKEGM_01768 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMBAKEGM_01769 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMBAKEGM_01770 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMBAKEGM_01771 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMBAKEGM_01772 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMBAKEGM_01773 1.1e-60 rplQ J Ribosomal protein L17
HMBAKEGM_01774 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMBAKEGM_01775 6.3e-162 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMBAKEGM_01776 6.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMBAKEGM_01777 4.6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMBAKEGM_01778 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMBAKEGM_01779 1.6e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
HMBAKEGM_01780 7.9e-61 S Protein of unknown function (DUF805)
HMBAKEGM_01781 1.2e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HMBAKEGM_01782 3.4e-65 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMBAKEGM_01783 9.8e-14 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMBAKEGM_01784 6.4e-134 S membrane transporter protein
HMBAKEGM_01785 2e-126 pgm3 G Belongs to the phosphoglycerate mutase family
HMBAKEGM_01786 1.1e-161 czcD P cation diffusion facilitator family transporter
HMBAKEGM_01787 2.5e-23
HMBAKEGM_01788 2.9e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMBAKEGM_01789 4.9e-184 S AAA domain
HMBAKEGM_01790 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMBAKEGM_01791 3.5e-25
HMBAKEGM_01793 4.8e-146 glcU U sugar transport
HMBAKEGM_01794 1.1e-264 pepC 3.4.22.40 E Peptidase C1-like family
HMBAKEGM_01795 4.5e-54
HMBAKEGM_01796 5.6e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HMBAKEGM_01797 1.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMBAKEGM_01798 1.1e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMBAKEGM_01799 2.9e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMBAKEGM_01800 7.9e-76 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMBAKEGM_01801 7.8e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMBAKEGM_01802 1.4e-93 sigH K Belongs to the sigma-70 factor family
HMBAKEGM_01803 2.2e-34
HMBAKEGM_01804 1.1e-283 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HMBAKEGM_01805 6.4e-88 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMBAKEGM_01806 3.9e-84 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMBAKEGM_01807 2.4e-98 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMBAKEGM_01808 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMBAKEGM_01809 1.4e-101 nusG K Participates in transcription elongation, termination and antitermination
HMBAKEGM_01810 2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMBAKEGM_01811 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMBAKEGM_01812 4.3e-158 pstS P Phosphate
HMBAKEGM_01813 3.7e-174 pstC P probably responsible for the translocation of the substrate across the membrane
HMBAKEGM_01814 7e-156 pstA P Phosphate transport system permease protein PstA
HMBAKEGM_01815 1.1e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMBAKEGM_01816 7.8e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMBAKEGM_01817 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
HMBAKEGM_01818 4.3e-27 yfdV S Membrane transport protein
HMBAKEGM_01819 1.6e-71 yfdV S Membrane transport protein
HMBAKEGM_01820 1.3e-77 yfdV S Membrane transport protein
HMBAKEGM_01821 5.4e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMBAKEGM_01822 2.4e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMBAKEGM_01823 2.8e-24 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HMBAKEGM_01824 1.1e-80 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HMBAKEGM_01825 1e-116 rsmC 2.1.1.172 J Methyltransferase
HMBAKEGM_01826 3.4e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMBAKEGM_01827 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMBAKEGM_01828 5e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMBAKEGM_01829 4.8e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMBAKEGM_01830 6.4e-35 S Protein of unknown function (DUF2508)
HMBAKEGM_01831 8.7e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMBAKEGM_01832 2.2e-51 yaaQ S Cyclic-di-AMP receptor
HMBAKEGM_01833 1.5e-155 holB 2.7.7.7 L DNA polymerase III
HMBAKEGM_01834 2.4e-59 yabA L Involved in initiation control of chromosome replication
HMBAKEGM_01835 7.9e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMBAKEGM_01836 1.6e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
HMBAKEGM_01837 3.4e-86 S ECF transporter, substrate-specific component
HMBAKEGM_01838 6.2e-134 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HMBAKEGM_01839 3.1e-104 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HMBAKEGM_01840 5.4e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMBAKEGM_01842 1.3e-24 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMBAKEGM_01843 1.8e-181 S Oxidoreductase family, NAD-binding Rossmann fold
HMBAKEGM_01844 2e-129 K UTRA
HMBAKEGM_01845 1.7e-234 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HMBAKEGM_01846 3.9e-38 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HMBAKEGM_01847 1.4e-73 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HMBAKEGM_01848 1.1e-26 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HMBAKEGM_01849 1.1e-37 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HMBAKEGM_01850 2.3e-135 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HMBAKEGM_01851 6.3e-46 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HMBAKEGM_01852 1.4e-12 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HMBAKEGM_01853 0.0 uup S ABC transporter, ATP-binding protein
HMBAKEGM_01854 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMBAKEGM_01855 4.4e-77 XK27_02470 K LytTr DNA-binding domain
HMBAKEGM_01856 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HMBAKEGM_01857 1.3e-109 S SNARE associated Golgi protein
HMBAKEGM_01858 8.8e-203 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HMBAKEGM_01859 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HMBAKEGM_01860 1.9e-26 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HMBAKEGM_01861 3.7e-23 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HMBAKEGM_01862 1.9e-212 yubA S AI-2E family transporter
HMBAKEGM_01863 5.5e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMBAKEGM_01864 1.4e-68 WQ51_03320 S Protein of unknown function (DUF1149)
HMBAKEGM_01865 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMBAKEGM_01866 1.8e-226 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HMBAKEGM_01867 1e-237 S Peptidase M16
HMBAKEGM_01868 5.8e-115 IQ Enoyl-(Acyl carrier protein) reductase
HMBAKEGM_01869 5.7e-12 IQ Enoyl-(Acyl carrier protein) reductase
HMBAKEGM_01870 1.4e-144 ymfM S Helix-turn-helix domain
HMBAKEGM_01871 2.5e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMBAKEGM_01872 5.5e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMBAKEGM_01873 9.5e-220 rny S Endoribonuclease that initiates mRNA decay
HMBAKEGM_01874 1.1e-40 tagO 2.7.8.33, 2.7.8.35 M transferase
HMBAKEGM_01875 1.3e-117 yvyE 3.4.13.9 S YigZ family
HMBAKEGM_01876 3.9e-248 comFA L Helicase C-terminal domain protein
HMBAKEGM_01877 2.6e-134 comFC S Competence protein
HMBAKEGM_01878 2.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMBAKEGM_01879 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMBAKEGM_01880 1.9e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMBAKEGM_01881 5.1e-19
HMBAKEGM_01882 7.6e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMBAKEGM_01883 3.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMBAKEGM_01884 3e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMBAKEGM_01885 8.9e-55 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMBAKEGM_01886 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMBAKEGM_01887 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMBAKEGM_01888 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMBAKEGM_01889 4.8e-165 rapZ S Displays ATPase and GTPase activities
HMBAKEGM_01890 2.6e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMBAKEGM_01891 1.4e-170 whiA K May be required for sporulation
HMBAKEGM_01892 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMBAKEGM_01893 0.0 S SH3-like domain
HMBAKEGM_01894 7.3e-153 S haloacid dehalogenase-like hydrolase
HMBAKEGM_01895 4.4e-59 ycaM E amino acid
HMBAKEGM_01896 3e-135 ycaM E amino acid
HMBAKEGM_01897 1.6e-188 cggR K Putative sugar-binding domain
HMBAKEGM_01898 1.3e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMBAKEGM_01899 9.3e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMBAKEGM_01900 2e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMBAKEGM_01901 4.8e-96
HMBAKEGM_01902 8.7e-159 ycsE S Sucrose-6F-phosphate phosphohydrolase
HMBAKEGM_01903 3.3e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMBAKEGM_01904 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HMBAKEGM_01905 6.4e-90 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HMBAKEGM_01906 2.3e-98 dnaQ 2.7.7.7 L DNA polymerase III
HMBAKEGM_01907 1.1e-164 murB 1.3.1.98 M Cell wall formation
HMBAKEGM_01908 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMBAKEGM_01909 1.3e-129 potB P ABC transporter permease
HMBAKEGM_01910 1.7e-132 potC P ABC transporter permease
HMBAKEGM_01911 5.6e-208 potD P ABC transporter
HMBAKEGM_01912 4.2e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMBAKEGM_01913 2.4e-170 ybbR S YbbR-like protein
HMBAKEGM_01914 1.3e-257 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMBAKEGM_01915 1.1e-150 S hydrolase
HMBAKEGM_01916 1.5e-149 S Sucrose-6F-phosphate phosphohydrolase
HMBAKEGM_01917 2.1e-118
HMBAKEGM_01918 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMBAKEGM_01919 3.5e-216 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMBAKEGM_01920 4.6e-64 licT K CAT RNA binding domain
HMBAKEGM_01921 3e-63 licT K CAT RNA binding domain
HMBAKEGM_01922 0.0 bglP G phosphotransferase system
HMBAKEGM_01923 4.7e-165 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMBAKEGM_01924 2.2e-39 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMBAKEGM_01925 4.3e-61 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMBAKEGM_01926 5.9e-185 D Alpha beta
HMBAKEGM_01927 1.5e-16 E Amino acid permease
HMBAKEGM_01928 2.9e-163 E Amino acid permease
HMBAKEGM_01929 3.3e-49 E Amino acid permease
HMBAKEGM_01930 4.6e-91 S VanZ like family
HMBAKEGM_01931 8.9e-133 yebC K Transcriptional regulatory protein
HMBAKEGM_01932 8.4e-179 comGA NU Type II IV secretion system protein
HMBAKEGM_01933 9e-176 comGB NU type II secretion system
HMBAKEGM_01934 3.7e-44 comGC U competence protein ComGC
HMBAKEGM_01935 2.1e-73
HMBAKEGM_01936 1e-41
HMBAKEGM_01937 8.9e-84 comGF U Putative Competence protein ComGF
HMBAKEGM_01938 1e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
HMBAKEGM_01939 7.2e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMBAKEGM_01941 7.9e-34 M Protein of unknown function (DUF3737)
HMBAKEGM_01942 1.1e-31 M Protein of unknown function (DUF3737)
HMBAKEGM_01943 1.1e-129 patB 4.4.1.8 E Aminotransferase, class I
HMBAKEGM_01944 5e-72 patB 4.4.1.8 E Aminotransferase, class I
HMBAKEGM_01945 1.7e-168 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMBAKEGM_01946 8.3e-61 S SdpI/YhfL protein family
HMBAKEGM_01947 8.3e-131 K Transcriptional regulatory protein, C terminal
HMBAKEGM_01948 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMBAKEGM_01949 8.3e-108 vanZ V VanZ like family
HMBAKEGM_01950 6.4e-262 pgi 5.3.1.9 G Belongs to the GPI family
HMBAKEGM_01951 7.7e-119 EGP Major facilitator Superfamily
HMBAKEGM_01952 4.4e-14 EGP Major facilitator Superfamily
HMBAKEGM_01953 4.6e-196 ampC V Beta-lactamase
HMBAKEGM_01956 1.5e-247 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HMBAKEGM_01957 7.6e-114 tdk 2.7.1.21 F thymidine kinase
HMBAKEGM_01958 5.3e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMBAKEGM_01959 6e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMBAKEGM_01960 1e-187 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMBAKEGM_01961 3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMBAKEGM_01962 7.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HMBAKEGM_01963 8.6e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMBAKEGM_01964 9.5e-49 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMBAKEGM_01965 2.3e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMBAKEGM_01966 2.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMBAKEGM_01967 1.3e-171 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMBAKEGM_01968 2.4e-238 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMBAKEGM_01969 2e-58 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMBAKEGM_01970 3.4e-30 ywzB S Protein of unknown function (DUF1146)
HMBAKEGM_01971 6.5e-179 mbl D Cell shape determining protein MreB Mrl
HMBAKEGM_01972 3.8e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HMBAKEGM_01973 8.6e-34 S Protein of unknown function (DUF2969)
HMBAKEGM_01974 1.5e-217 rodA D Belongs to the SEDS family
HMBAKEGM_01975 3.1e-78 usp6 T universal stress protein
HMBAKEGM_01976 2.5e-35
HMBAKEGM_01977 2.7e-241 rarA L recombination factor protein RarA
HMBAKEGM_01978 2.7e-82 yueI S Protein of unknown function (DUF1694)
HMBAKEGM_01979 1.8e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMBAKEGM_01980 2.7e-281 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMBAKEGM_01981 4.2e-217 iscS2 2.8.1.7 E Aminotransferase class V
HMBAKEGM_01982 1.7e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMBAKEGM_01983 3.7e-141 K Helix-turn-helix domain
HMBAKEGM_01984 4.9e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMBAKEGM_01985 2e-14 K Helix-turn-helix XRE-family like proteins
HMBAKEGM_01986 1.1e-65
HMBAKEGM_01987 1.1e-89
HMBAKEGM_01988 9.9e-132 K Helix-turn-helix XRE-family like proteins
HMBAKEGM_01989 1.2e-271 S SLAP domain
HMBAKEGM_01990 2.2e-71 S Protein of unknown function (DUF3232)
HMBAKEGM_01992 1.9e-83
HMBAKEGM_01993 1.6e-22
HMBAKEGM_01994 1.4e-07 K Helix-turn-helix XRE-family like proteins
HMBAKEGM_01995 1.7e-07 K Helix-turn-helix XRE-family like proteins

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)