ORF_ID e_value Gene_name EC_number CAZy COGs Description
AKKDOMIM_00001 1.2e-79
AKKDOMIM_00002 1.8e-136 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00003 4.1e-98 S SLAP domain
AKKDOMIM_00004 4.3e-152 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00005 1.2e-94
AKKDOMIM_00006 5e-200
AKKDOMIM_00007 5.1e-69
AKKDOMIM_00008 6e-61 L Transposase
AKKDOMIM_00009 1.3e-105 S Protein of unknown function (DUF3232)
AKKDOMIM_00010 3.6e-39 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00011 7.3e-46
AKKDOMIM_00012 2.5e-155
AKKDOMIM_00013 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AKKDOMIM_00014 4.7e-43 3.6.4.12 S PD-(D/E)XK nuclease family transposase
AKKDOMIM_00015 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
AKKDOMIM_00016 6.2e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
AKKDOMIM_00017 1.5e-94 S Protein of unknown function (DUF3990)
AKKDOMIM_00018 2.9e-44
AKKDOMIM_00020 0.0 3.6.3.8 P P-type ATPase
AKKDOMIM_00021 3.3e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
AKKDOMIM_00022 2.5e-52
AKKDOMIM_00023 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AKKDOMIM_00024 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AKKDOMIM_00025 5.7e-126 S Haloacid dehalogenase-like hydrolase
AKKDOMIM_00026 2.3e-108 radC L DNA repair protein
AKKDOMIM_00027 2.4e-176 mreB D cell shape determining protein MreB
AKKDOMIM_00028 2e-147 mreC M Involved in formation and maintenance of cell shape
AKKDOMIM_00029 2.7e-94 mreD
AKKDOMIM_00031 6.4e-54 S Protein of unknown function (DUF3397)
AKKDOMIM_00032 6.3e-78 mraZ K Belongs to the MraZ family
AKKDOMIM_00033 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AKKDOMIM_00034 1.8e-54 ftsL D Cell division protein FtsL
AKKDOMIM_00035 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
AKKDOMIM_00036 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AKKDOMIM_00037 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AKKDOMIM_00038 5.7e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AKKDOMIM_00039 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AKKDOMIM_00040 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AKKDOMIM_00041 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AKKDOMIM_00042 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AKKDOMIM_00043 1.7e-45 yggT S YGGT family
AKKDOMIM_00044 8.2e-148 ylmH S S4 domain protein
AKKDOMIM_00045 2.8e-74 gpsB D DivIVA domain protein
AKKDOMIM_00046 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AKKDOMIM_00047 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
AKKDOMIM_00048 1.4e-101 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
AKKDOMIM_00049 6.7e-37
AKKDOMIM_00050 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AKKDOMIM_00051 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
AKKDOMIM_00052 5.4e-56 XK27_04120 S Putative amino acid metabolism
AKKDOMIM_00053 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AKKDOMIM_00054 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
AKKDOMIM_00055 8.3e-106 S Repeat protein
AKKDOMIM_00056 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AKKDOMIM_00057 1.6e-294 L Nuclease-related domain
AKKDOMIM_00058 1.2e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
AKKDOMIM_00059 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AKKDOMIM_00060 3.5e-32 ykzG S Belongs to the UPF0356 family
AKKDOMIM_00061 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AKKDOMIM_00062 0.0 typA T GTP-binding protein TypA
AKKDOMIM_00063 2.7e-211 ftsW D Belongs to the SEDS family
AKKDOMIM_00064 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
AKKDOMIM_00065 1.3e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
AKKDOMIM_00066 1.1e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AKKDOMIM_00067 6.9e-187 ylbL T Belongs to the peptidase S16 family
AKKDOMIM_00068 3.1e-79 comEA L Competence protein ComEA
AKKDOMIM_00069 0.0 comEC S Competence protein ComEC
AKKDOMIM_00070 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
AKKDOMIM_00071 6.7e-35 rpsT J Binds directly to 16S ribosomal RNA
AKKDOMIM_00072 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AKKDOMIM_00073 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AKKDOMIM_00074 1.3e-148
AKKDOMIM_00075 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AKKDOMIM_00076 4e-216 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AKKDOMIM_00077 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AKKDOMIM_00078 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
AKKDOMIM_00079 7.8e-39 yjeM E Amino Acid
AKKDOMIM_00080 3.4e-175 yjeM E Amino Acid
AKKDOMIM_00081 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AKKDOMIM_00082 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
AKKDOMIM_00083 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AKKDOMIM_00084 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AKKDOMIM_00085 5.2e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AKKDOMIM_00086 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AKKDOMIM_00087 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AKKDOMIM_00088 2.3e-215 aspC 2.6.1.1 E Aminotransferase
AKKDOMIM_00089 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AKKDOMIM_00090 4.7e-194 pbpX1 V Beta-lactamase
AKKDOMIM_00091 4.6e-299 I Protein of unknown function (DUF2974)
AKKDOMIM_00092 1.8e-38 C FMN_bind
AKKDOMIM_00093 3.9e-82
AKKDOMIM_00094 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
AKKDOMIM_00095 6.4e-90 alkD L DNA alkylation repair enzyme
AKKDOMIM_00096 6.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AKKDOMIM_00097 1.1e-127 K UTRA domain
AKKDOMIM_00098 1.6e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
AKKDOMIM_00099 4.3e-59 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
AKKDOMIM_00100 3.2e-11
AKKDOMIM_00101 1.6e-61
AKKDOMIM_00102 1.1e-248 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKKDOMIM_00103 3.2e-71 S Domain of unknown function (DUF3284)
AKKDOMIM_00104 5.4e-302 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AKKDOMIM_00105 4.2e-119 gmuR K UTRA
AKKDOMIM_00106 3.7e-223 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKKDOMIM_00107 5.8e-274 bglA3 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AKKDOMIM_00108 9.2e-137 ypbG 2.7.1.2 GK ROK family
AKKDOMIM_00109 4.4e-36 C nitroreductase
AKKDOMIM_00110 8e-38 C nitroreductase
AKKDOMIM_00111 7.5e-91 S Domain of unknown function (DUF4767)
AKKDOMIM_00112 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AKKDOMIM_00113 2.2e-151 yitS S Uncharacterised protein, DegV family COG1307
AKKDOMIM_00114 4.6e-100 3.6.1.27 I Acid phosphatase homologues
AKKDOMIM_00115 4.2e-178 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
AKKDOMIM_00117 1.6e-172 MA20_14895 S Conserved hypothetical protein 698
AKKDOMIM_00118 6.3e-26 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
AKKDOMIM_00119 1.9e-30 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
AKKDOMIM_00120 1e-284 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
AKKDOMIM_00121 1.2e-30 copZ C Heavy-metal-associated domain
AKKDOMIM_00122 1.6e-78 dps P Belongs to the Dps family
AKKDOMIM_00123 1.9e-86 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
AKKDOMIM_00124 2e-129 yobV1 K WYL domain
AKKDOMIM_00125 1.8e-55 S pyridoxamine 5-phosphate
AKKDOMIM_00126 3.8e-84 dps P Belongs to the Dps family
AKKDOMIM_00127 1.7e-151
AKKDOMIM_00129 1.3e-246 ydaM M Glycosyl transferase
AKKDOMIM_00130 3.5e-205 G Glycosyl hydrolases family 8
AKKDOMIM_00131 1.1e-67 L Transposase and inactivated derivatives, IS30 family
AKKDOMIM_00132 2.2e-14 L Transposase and inactivated derivatives, IS30 family
AKKDOMIM_00133 5.8e-13 L Transposase and inactivated derivatives, IS30 family
AKKDOMIM_00134 2.4e-10 L Psort location Cytoplasmic, score
AKKDOMIM_00135 4e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
AKKDOMIM_00136 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
AKKDOMIM_00137 2.2e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
AKKDOMIM_00138 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
AKKDOMIM_00139 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AKKDOMIM_00141 4.8e-138 L An automated process has identified a potential problem with this gene model
AKKDOMIM_00142 2.8e-48 S Peptidase propeptide and YPEB domain
AKKDOMIM_00143 6.5e-169 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
AKKDOMIM_00144 7.2e-183 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
AKKDOMIM_00145 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
AKKDOMIM_00146 2e-155 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
AKKDOMIM_00147 5e-125 C 2Fe-2S iron-sulfur cluster binding domain
AKKDOMIM_00148 2.8e-140 sufC O FeS assembly ATPase SufC
AKKDOMIM_00149 3.5e-174 sufD O FeS assembly protein SufD
AKKDOMIM_00150 5.3e-178 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AKKDOMIM_00151 2.4e-59 nifU C SUF system FeS assembly protein, NifU family
AKKDOMIM_00152 2e-266 sufB O assembly protein SufB
AKKDOMIM_00153 2.4e-45 yitW S Iron-sulfur cluster assembly protein
AKKDOMIM_00154 2.9e-247 mntH P H( )-stimulated, divalent metal cation uptake system
AKKDOMIM_00155 7.7e-10 C Flavodoxin
AKKDOMIM_00156 3.2e-79 S X-Pro dipeptidyl-peptidase (S15 family)
AKKDOMIM_00157 3.3e-45 K Tetracycline repressor, C-terminal all-alpha domain
AKKDOMIM_00159 6.6e-90 K LysR substrate binding domain
AKKDOMIM_00160 8.9e-34 S Domain of unknown function (DUF4440)
AKKDOMIM_00161 1.3e-68 GM NAD(P)H-binding
AKKDOMIM_00162 7e-135 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
AKKDOMIM_00163 1.2e-49 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AKKDOMIM_00164 1.9e-237 brnQ U Component of the transport system for branched-chain amino acids
AKKDOMIM_00165 2.8e-24 S Alpha beta hydrolase
AKKDOMIM_00166 2.4e-273 lsa S ABC transporter
AKKDOMIM_00167 3.5e-107 S Protein of unknown function (DUF1211)
AKKDOMIM_00168 5.5e-33
AKKDOMIM_00169 8.1e-123 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AKKDOMIM_00170 8.8e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AKKDOMIM_00171 6.7e-215 iscS2 2.8.1.7 E Aminotransferase class V
AKKDOMIM_00172 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AKKDOMIM_00173 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AKKDOMIM_00174 1.3e-84 yueI S Protein of unknown function (DUF1694)
AKKDOMIM_00175 2.2e-238 rarA L recombination factor protein RarA
AKKDOMIM_00176 8.4e-39
AKKDOMIM_00177 1.8e-78 usp6 T universal stress protein
AKKDOMIM_00178 4.7e-216 rodA D Belongs to the SEDS family
AKKDOMIM_00179 3.3e-33 S Protein of unknown function (DUF2969)
AKKDOMIM_00180 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AKKDOMIM_00181 1.2e-177 mbl D Cell shape determining protein MreB Mrl
AKKDOMIM_00182 2e-30 ywzB S Protein of unknown function (DUF1146)
AKKDOMIM_00183 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AKKDOMIM_00184 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AKKDOMIM_00185 2e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AKKDOMIM_00186 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AKKDOMIM_00187 6.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKKDOMIM_00188 3.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AKKDOMIM_00189 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AKKDOMIM_00190 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
AKKDOMIM_00191 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AKKDOMIM_00192 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AKKDOMIM_00193 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AKKDOMIM_00194 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AKKDOMIM_00195 1.3e-113 tdk 2.7.1.21 F thymidine kinase
AKKDOMIM_00196 1.7e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
AKKDOMIM_00199 3.9e-195 ampC V Beta-lactamase
AKKDOMIM_00200 2.4e-216 EGP Major facilitator Superfamily
AKKDOMIM_00201 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
AKKDOMIM_00202 3.8e-105 vanZ V VanZ like family
AKKDOMIM_00203 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AKKDOMIM_00204 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
AKKDOMIM_00205 4.4e-129 K Transcriptional regulatory protein, C terminal
AKKDOMIM_00206 7.7e-67 S SdpI/YhfL protein family
AKKDOMIM_00207 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
AKKDOMIM_00208 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
AKKDOMIM_00209 1.3e-88 M Protein of unknown function (DUF3737)
AKKDOMIM_00210 7.6e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
AKKDOMIM_00211 1e-12
AKKDOMIM_00213 1.1e-163 L An automated process has identified a potential problem with this gene model
AKKDOMIM_00214 5e-97 D VirC1 protein
AKKDOMIM_00216 5e-39 relB L RelB antitoxin
AKKDOMIM_00217 1.1e-34 S Bacterial toxin of type II toxin-antitoxin system, YafQ
AKKDOMIM_00218 6.5e-82 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
AKKDOMIM_00219 7.3e-241 V N-6 DNA Methylase
AKKDOMIM_00221 1e-66 doc S Fic/DOC family
AKKDOMIM_00222 1.1e-34
AKKDOMIM_00223 1.1e-23 S CAAX protease self-immunity
AKKDOMIM_00225 9.8e-134 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
AKKDOMIM_00227 8.1e-17 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
AKKDOMIM_00228 3.4e-24 relB L Addiction module antitoxin, RelB DinJ family
AKKDOMIM_00229 1.2e-48 E Pfam:DUF955
AKKDOMIM_00230 6.3e-16 L Protein of unknown function (DUF3991)
AKKDOMIM_00231 4.2e-38 L Protein of unknown function (DUF3991)
AKKDOMIM_00232 1.8e-53 S COG0790 FOG TPR repeat, SEL1 subfamily
AKKDOMIM_00238 2.4e-18 CO COG0526, thiol-disulfide isomerase and thioredoxins
AKKDOMIM_00241 3.2e-33 3.5.1.28 NU amidase activity
AKKDOMIM_00242 8.1e-160 trsE S COG0433 Predicted ATPase
AKKDOMIM_00243 8.4e-15
AKKDOMIM_00245 2.3e-32 I mechanosensitive ion channel activity
AKKDOMIM_00246 1.4e-141 U TraM recognition site of TraD and TraG
AKKDOMIM_00250 1.3e-30 M domain protein
AKKDOMIM_00251 6.8e-15 S SLAP domain
AKKDOMIM_00252 1.3e-39 M domain protein
AKKDOMIM_00254 7e-24 srtA 3.4.22.70 M sortase family
AKKDOMIM_00260 2.6e-11 ssb L Single-strand binding protein family
AKKDOMIM_00267 1e-25 S Domain of unknown function (DUF771)
AKKDOMIM_00268 9e-21 K Conserved phage C-terminus (Phg_2220_C)
AKKDOMIM_00270 4.1e-09 S Arc-like DNA binding domain
AKKDOMIM_00272 2.6e-31 K Helix-turn-helix domain
AKKDOMIM_00273 9e-22 XK27_07105 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00274 1.2e-23 K Helix-turn-helix domain
AKKDOMIM_00275 5e-08 S Pfam:DUF955
AKKDOMIM_00276 1.8e-153 L Belongs to the 'phage' integrase family
AKKDOMIM_00278 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AKKDOMIM_00279 3.5e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
AKKDOMIM_00280 1.6e-21
AKKDOMIM_00281 9.4e-76 comGF U Putative Competence protein ComGF
AKKDOMIM_00282 8.6e-41
AKKDOMIM_00283 7.4e-71
AKKDOMIM_00284 3.1e-43 comGC U competence protein ComGC
AKKDOMIM_00285 1.7e-171 comGB NU type II secretion system
AKKDOMIM_00286 1.7e-179 comGA NU Type II IV secretion system protein
AKKDOMIM_00287 8.9e-133 yebC K Transcriptional regulatory protein
AKKDOMIM_00288 2.9e-93 S VanZ like family
AKKDOMIM_00289 5.1e-108 ylbE GM NAD(P)H-binding
AKKDOMIM_00290 9.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AKKDOMIM_00292 2.8e-304 E Amino acid permease
AKKDOMIM_00293 6.9e-178 D Alpha beta
AKKDOMIM_00294 9.1e-302 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AKKDOMIM_00295 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
AKKDOMIM_00296 8.3e-143 licT K CAT RNA binding domain
AKKDOMIM_00297 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AKKDOMIM_00298 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AKKDOMIM_00299 1.4e-117
AKKDOMIM_00300 1.8e-75 K Penicillinase repressor
AKKDOMIM_00301 1.4e-147 S hydrolase
AKKDOMIM_00302 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AKKDOMIM_00303 2e-172 ybbR S YbbR-like protein
AKKDOMIM_00304 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AKKDOMIM_00305 7.3e-208 potD P ABC transporter
AKKDOMIM_00306 4.8e-127 potC P ABC transporter permease
AKKDOMIM_00307 1.3e-129 potB P ABC transporter permease
AKKDOMIM_00308 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AKKDOMIM_00309 2e-163 murB 1.3.1.98 M Cell wall formation
AKKDOMIM_00310 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
AKKDOMIM_00311 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
AKKDOMIM_00312 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
AKKDOMIM_00313 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AKKDOMIM_00314 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
AKKDOMIM_00315 1.2e-94
AKKDOMIM_00316 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
AKKDOMIM_00317 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AKKDOMIM_00318 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AKKDOMIM_00319 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AKKDOMIM_00320 3.3e-189 cggR K Putative sugar-binding domain
AKKDOMIM_00322 2.8e-290
AKKDOMIM_00323 3.9e-273 ycaM E amino acid
AKKDOMIM_00324 3.1e-139 S Cysteine-rich secretory protein family
AKKDOMIM_00325 4.2e-77 K MerR HTH family regulatory protein
AKKDOMIM_00326 1.4e-262 lmrB EGP Major facilitator Superfamily
AKKDOMIM_00327 3.1e-48 S Domain of unknown function (DUF4811)
AKKDOMIM_00328 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
AKKDOMIM_00329 4.9e-111 ybbL S ABC transporter, ATP-binding protein
AKKDOMIM_00330 0.0 S SH3-like domain
AKKDOMIM_00331 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AKKDOMIM_00332 2.1e-171 whiA K May be required for sporulation
AKKDOMIM_00333 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AKKDOMIM_00334 6.2e-165 rapZ S Displays ATPase and GTPase activities
AKKDOMIM_00335 4.1e-90 S Short repeat of unknown function (DUF308)
AKKDOMIM_00336 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AKKDOMIM_00337 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AKKDOMIM_00338 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
AKKDOMIM_00339 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AKKDOMIM_00340 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AKKDOMIM_00341 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AKKDOMIM_00342 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AKKDOMIM_00343 5.1e-17
AKKDOMIM_00344 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AKKDOMIM_00345 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AKKDOMIM_00346 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AKKDOMIM_00347 9.4e-132 comFC S Competence protein
AKKDOMIM_00348 1.4e-245 comFA L Helicase C-terminal domain protein
AKKDOMIM_00349 5.1e-119 yvyE 3.4.13.9 S YigZ family
AKKDOMIM_00350 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
AKKDOMIM_00351 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
AKKDOMIM_00352 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AKKDOMIM_00353 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AKKDOMIM_00354 2.1e-95 ymfM S Helix-turn-helix domain
AKKDOMIM_00355 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
AKKDOMIM_00356 1.9e-236 S Peptidase M16
AKKDOMIM_00357 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
AKKDOMIM_00358 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
AKKDOMIM_00359 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
AKKDOMIM_00360 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AKKDOMIM_00361 2.6e-214 yubA S AI-2E family transporter
AKKDOMIM_00362 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
AKKDOMIM_00363 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
AKKDOMIM_00364 4.2e-92 S SNARE associated Golgi protein
AKKDOMIM_00365 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
AKKDOMIM_00366 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AKKDOMIM_00367 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AKKDOMIM_00368 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
AKKDOMIM_00369 5.2e-110 yjbK S CYTH
AKKDOMIM_00370 4.6e-114 yjbH Q Thioredoxin
AKKDOMIM_00371 4e-13 coiA 3.6.4.12 S Competence protein
AKKDOMIM_00372 3.3e-122 coiA 3.6.4.12 S Competence protein
AKKDOMIM_00373 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AKKDOMIM_00374 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AKKDOMIM_00375 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AKKDOMIM_00376 8.5e-41 ptsH G phosphocarrier protein HPR
AKKDOMIM_00377 0.0 clpE O Belongs to the ClpA ClpB family
AKKDOMIM_00378 8.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
AKKDOMIM_00379 2.1e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AKKDOMIM_00380 1.2e-141 hlyX S Transporter associated domain
AKKDOMIM_00381 1.6e-74
AKKDOMIM_00382 7.8e-85
AKKDOMIM_00383 3e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
AKKDOMIM_00384 1.2e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKKDOMIM_00385 2.2e-119 D Alpha beta
AKKDOMIM_00386 2.9e-27 D Alpha beta
AKKDOMIM_00387 1e-44
AKKDOMIM_00388 1.2e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
AKKDOMIM_00389 5.9e-214 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
AKKDOMIM_00390 5.6e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
AKKDOMIM_00391 7.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AKKDOMIM_00392 8e-163 yihY S Belongs to the UPF0761 family
AKKDOMIM_00393 6.5e-164 map 3.4.11.18 E Methionine Aminopeptidase
AKKDOMIM_00394 4.1e-80 fld C Flavodoxin
AKKDOMIM_00395 3.1e-87 gtcA S Teichoic acid glycosylation protein
AKKDOMIM_00396 5.9e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AKKDOMIM_00398 3.1e-248 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKKDOMIM_00399 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
AKKDOMIM_00400 1.1e-130 M Glycosyl hydrolases family 25
AKKDOMIM_00401 2.8e-230 potE E amino acid
AKKDOMIM_00402 0.0 1.3.5.4 C FAD binding domain
AKKDOMIM_00403 1.2e-49 L PFAM transposase, IS4 family protein
AKKDOMIM_00404 1.1e-87 L PFAM transposase, IS4 family protein
AKKDOMIM_00405 0.0 1.3.5.4 C FAD binding domain
AKKDOMIM_00406 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AKKDOMIM_00407 1.7e-249 yhdP S Transporter associated domain
AKKDOMIM_00408 3.9e-119 C nitroreductase
AKKDOMIM_00409 2.1e-39
AKKDOMIM_00410 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
AKKDOMIM_00411 1.6e-80
AKKDOMIM_00412 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
AKKDOMIM_00413 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
AKKDOMIM_00414 5.4e-147 S hydrolase
AKKDOMIM_00415 2e-160 rssA S Phospholipase, patatin family
AKKDOMIM_00416 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
AKKDOMIM_00417 3.1e-136 glcR K DeoR C terminal sensor domain
AKKDOMIM_00418 2.5e-59 S Enterocin A Immunity
AKKDOMIM_00419 1e-153 S hydrolase
AKKDOMIM_00420 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
AKKDOMIM_00421 9.1e-175 rihB 3.2.2.1 F Nucleoside
AKKDOMIM_00422 0.0 kup P Transport of potassium into the cell
AKKDOMIM_00423 3.4e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AKKDOMIM_00424 5.4e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AKKDOMIM_00425 1.3e-161 2.7.7.12 C Domain of unknown function (DUF4931)
AKKDOMIM_00426 8.6e-221 G Bacterial extracellular solute-binding protein
AKKDOMIM_00427 2e-210 S Uncharacterized protein conserved in bacteria (DUF2325)
AKKDOMIM_00429 1.7e-28 mloB K Putative ATP-dependent DNA helicase recG C-terminal
AKKDOMIM_00430 3.5e-248 lctP C L-lactate permease
AKKDOMIM_00431 5e-129 znuB U ABC 3 transport family
AKKDOMIM_00432 1.6e-117 fhuC P ABC transporter
AKKDOMIM_00433 1.4e-148 psaA P Belongs to the bacterial solute-binding protein 9 family
AKKDOMIM_00434 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
AKKDOMIM_00435 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
AKKDOMIM_00436 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AKKDOMIM_00437 1.8e-136 fruR K DeoR C terminal sensor domain
AKKDOMIM_00438 1.8e-218 natB CP ABC-2 family transporter protein
AKKDOMIM_00439 1.1e-164 natA S ABC transporter, ATP-binding protein
AKKDOMIM_00440 1.7e-67
AKKDOMIM_00441 2e-23
AKKDOMIM_00442 8.2e-31 yozG K Transcriptional regulator
AKKDOMIM_00443 3.7e-83
AKKDOMIM_00444 3e-21
AKKDOMIM_00448 2.2e-129 blpT
AKKDOMIM_00449 1.4e-107 M Transport protein ComB
AKKDOMIM_00450 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AKKDOMIM_00451 1.2e-127 K LytTr DNA-binding domain
AKKDOMIM_00452 4.4e-138 2.7.13.3 T GHKL domain
AKKDOMIM_00453 1.2e-16
AKKDOMIM_00454 2.1e-255 S Archaea bacterial proteins of unknown function
AKKDOMIM_00455 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
AKKDOMIM_00456 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
AKKDOMIM_00457 1e-24
AKKDOMIM_00458 9.5e-26
AKKDOMIM_00459 2.5e-33
AKKDOMIM_00460 1.4e-53 S Enterocin A Immunity
AKKDOMIM_00461 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
AKKDOMIM_00462 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AKKDOMIM_00463 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
AKKDOMIM_00464 9.6e-121 K response regulator
AKKDOMIM_00465 0.0 V ABC transporter
AKKDOMIM_00466 4.2e-144 V ABC transporter, ATP-binding protein
AKKDOMIM_00467 1.2e-145 V ABC transporter, ATP-binding protein
AKKDOMIM_00468 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
AKKDOMIM_00469 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AKKDOMIM_00470 2.8e-44 yyzM S Bacterial protein of unknown function (DUF951)
AKKDOMIM_00471 1.5e-153 spo0J K Belongs to the ParB family
AKKDOMIM_00472 3.4e-138 soj D Sporulation initiation inhibitor
AKKDOMIM_00473 5e-148 noc K Belongs to the ParB family
AKKDOMIM_00474 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
AKKDOMIM_00475 3e-53 cvpA S Colicin V production protein
AKKDOMIM_00477 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AKKDOMIM_00478 6e-151 3.1.3.48 T Tyrosine phosphatase family
AKKDOMIM_00479 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
AKKDOMIM_00480 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
AKKDOMIM_00481 3.7e-111 K WHG domain
AKKDOMIM_00482 8e-38
AKKDOMIM_00483 3.8e-273 pipD E Dipeptidase
AKKDOMIM_00484 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
AKKDOMIM_00485 9.5e-176 hrtB V ABC transporter permease
AKKDOMIM_00486 1.4e-90 ygfC K Bacterial regulatory proteins, tetR family
AKKDOMIM_00487 3.5e-111 G phosphoglycerate mutase
AKKDOMIM_00488 6.2e-183 L DDE superfamily endonuclease
AKKDOMIM_00489 4.1e-141 aroD S Alpha/beta hydrolase family
AKKDOMIM_00490 2.2e-142 S Belongs to the UPF0246 family
AKKDOMIM_00491 9e-121
AKKDOMIM_00492 9.7e-157 2.7.7.12 C Domain of unknown function (DUF4931)
AKKDOMIM_00493 1.2e-190 S Putative peptidoglycan binding domain
AKKDOMIM_00494 4e-16
AKKDOMIM_00495 7.9e-92 liaI S membrane
AKKDOMIM_00496 1.7e-70 XK27_02470 K LytTr DNA-binding domain
AKKDOMIM_00498 5.3e-249 dtpT U amino acid peptide transporter
AKKDOMIM_00499 2.4e-35 L Transposase DDE domain
AKKDOMIM_00500 3.7e-260 L Transposase
AKKDOMIM_00501 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKKDOMIM_00502 7.9e-73 nrdI F NrdI Flavodoxin like
AKKDOMIM_00503 1.4e-192 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKKDOMIM_00504 2.5e-276 phoR 2.7.13.3 T Histidine kinase
AKKDOMIM_00505 8.9e-119 T Transcriptional regulatory protein, C terminal
AKKDOMIM_00506 1.2e-104 phoU P Plays a role in the regulation of phosphate uptake
AKKDOMIM_00507 1.5e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AKKDOMIM_00508 4.6e-152 pstA P Phosphate transport system permease protein PstA
AKKDOMIM_00509 1.3e-154 pstC P probably responsible for the translocation of the substrate across the membrane
AKKDOMIM_00510 3.2e-145 pstS P Phosphate
AKKDOMIM_00511 3.2e-26 xerC L Phage integrase, N-terminal SAM-like domain
AKKDOMIM_00512 2.3e-82 yveB 2.7.4.29 I PAP2 superfamily
AKKDOMIM_00513 0.0 pepN 3.4.11.2 E aminopeptidase
AKKDOMIM_00514 2.8e-47 lysM M LysM domain
AKKDOMIM_00515 7.4e-175
AKKDOMIM_00516 4.3e-212 mdtG EGP Major facilitator Superfamily
AKKDOMIM_00517 6.7e-88 ymdB S Macro domain protein
AKKDOMIM_00519 6.7e-09
AKKDOMIM_00520 1.6e-28
AKKDOMIM_00523 1.5e-59 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00524 3.3e-147 malG P ABC transporter permease
AKKDOMIM_00525 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
AKKDOMIM_00526 2.3e-213 malE G Bacterial extracellular solute-binding protein
AKKDOMIM_00527 3e-209 msmX P Belongs to the ABC transporter superfamily
AKKDOMIM_00528 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
AKKDOMIM_00529 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
AKKDOMIM_00530 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
AKKDOMIM_00531 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
AKKDOMIM_00532 4.2e-56 S PAS domain
AKKDOMIM_00533 9.1e-204 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AKKDOMIM_00534 3.1e-178 yvdE K helix_turn _helix lactose operon repressor
AKKDOMIM_00535 7e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
AKKDOMIM_00536 3.9e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AKKDOMIM_00537 9.6e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AKKDOMIM_00538 2.3e-18
AKKDOMIM_00539 4e-137 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00541 2.3e-121 V Abi-like protein
AKKDOMIM_00542 6.8e-186 G Transmembrane secretion effector
AKKDOMIM_00543 6.1e-136 V ABC transporter transmembrane region
AKKDOMIM_00544 2.9e-79 L transposase, IS605 OrfB family
AKKDOMIM_00545 1.1e-75 V ABC transporter transmembrane region
AKKDOMIM_00546 6.5e-64 L RelB antitoxin
AKKDOMIM_00547 2.1e-131 cobQ S glutamine amidotransferase
AKKDOMIM_00548 1.8e-81 M NlpC/P60 family
AKKDOMIM_00551 2.6e-155
AKKDOMIM_00552 7.8e-38
AKKDOMIM_00553 2e-32
AKKDOMIM_00554 6.2e-163 EG EamA-like transporter family
AKKDOMIM_00555 5e-165 EG EamA-like transporter family
AKKDOMIM_00556 1.2e-139 yicL EG EamA-like transporter family
AKKDOMIM_00557 4.3e-107
AKKDOMIM_00558 1.1e-110
AKKDOMIM_00559 5.8e-186 XK27_05540 S DUF218 domain
AKKDOMIM_00560 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
AKKDOMIM_00561 7.2e-86
AKKDOMIM_00562 3.9e-57
AKKDOMIM_00563 4.7e-25 S Protein conserved in bacteria
AKKDOMIM_00564 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
AKKDOMIM_00566 1.8e-26 L Transposase
AKKDOMIM_00567 7.3e-21 hicA S HicA toxin of bacterial toxin-antitoxin,
AKKDOMIM_00568 2.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AKKDOMIM_00569 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AKKDOMIM_00570 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AKKDOMIM_00573 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
AKKDOMIM_00574 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
AKKDOMIM_00575 1.8e-230 steT_1 E amino acid
AKKDOMIM_00576 2.2e-139 puuD S peptidase C26
AKKDOMIM_00578 2.4e-172 V HNH endonuclease
AKKDOMIM_00579 6.4e-135 S PFAM Archaeal ATPase
AKKDOMIM_00580 9.2e-248 yifK E Amino acid permease
AKKDOMIM_00581 9.7e-234 cycA E Amino acid permease
AKKDOMIM_00582 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AKKDOMIM_00583 0.0 clpE O AAA domain (Cdc48 subfamily)
AKKDOMIM_00584 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
AKKDOMIM_00585 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKKDOMIM_00586 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
AKKDOMIM_00587 0.0 XK27_06780 V ABC transporter permease
AKKDOMIM_00588 1.9e-36
AKKDOMIM_00589 7.9e-291 ytgP S Polysaccharide biosynthesis protein
AKKDOMIM_00590 2.7e-137 lysA2 M Glycosyl hydrolases family 25
AKKDOMIM_00591 2.3e-133 S Protein of unknown function (DUF975)
AKKDOMIM_00592 2.9e-176 pbpX2 V Beta-lactamase
AKKDOMIM_00593 1.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AKKDOMIM_00594 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AKKDOMIM_00595 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
AKKDOMIM_00596 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AKKDOMIM_00597 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
AKKDOMIM_00598 4.1e-44
AKKDOMIM_00599 1e-207 ywhK S Membrane
AKKDOMIM_00600 1.5e-80 ykuL S (CBS) domain
AKKDOMIM_00601 0.0 cadA P P-type ATPase
AKKDOMIM_00602 2.8e-205 napA P Sodium/hydrogen exchanger family
AKKDOMIM_00603 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
AKKDOMIM_00604 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
AKKDOMIM_00605 4.1e-276 V ABC transporter transmembrane region
AKKDOMIM_00606 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00607 5.4e-51
AKKDOMIM_00608 4.2e-154 EGP Major facilitator Superfamily
AKKDOMIM_00609 1.6e-109 ropB K Transcriptional regulator
AKKDOMIM_00610 9.1e-121 S CAAX protease self-immunity
AKKDOMIM_00611 3.7e-191 S DUF218 domain
AKKDOMIM_00612 0.0 macB_3 V ABC transporter, ATP-binding protein
AKKDOMIM_00613 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AKKDOMIM_00614 2.8e-100 S ECF transporter, substrate-specific component
AKKDOMIM_00615 2.3e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
AKKDOMIM_00616 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
AKKDOMIM_00617 2e-283 xylG 3.6.3.17 S ABC transporter
AKKDOMIM_00618 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
AKKDOMIM_00619 4.4e-172 yufQ S Belongs to the binding-protein-dependent transport system permease family
AKKDOMIM_00620 1.1e-68 yeaE S Aldo/keto reductase family
AKKDOMIM_00621 1.8e-77 yeaE S Aldo/keto reductase family
AKKDOMIM_00622 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AKKDOMIM_00623 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AKKDOMIM_00624 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
AKKDOMIM_00625 2.7e-71
AKKDOMIM_00626 7e-139 cof S haloacid dehalogenase-like hydrolase
AKKDOMIM_00627 2.2e-230 pbuG S permease
AKKDOMIM_00628 2.1e-76 S ABC-2 family transporter protein
AKKDOMIM_00629 4.7e-60 S ABC-2 family transporter protein
AKKDOMIM_00630 1.7e-93 V ABC transporter, ATP-binding protein
AKKDOMIM_00631 3.9e-58
AKKDOMIM_00632 2.5e-119 K helix_turn_helix, mercury resistance
AKKDOMIM_00633 2.6e-86 pbuG S permease
AKKDOMIM_00634 1.8e-128 pbuG S permease
AKKDOMIM_00635 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
AKKDOMIM_00636 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
AKKDOMIM_00637 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
AKKDOMIM_00638 1.3e-94 K Transcriptional regulator
AKKDOMIM_00639 6.1e-61 K Transcriptional regulator
AKKDOMIM_00640 2e-225 S cog cog1373
AKKDOMIM_00641 9.7e-146 S haloacid dehalogenase-like hydrolase
AKKDOMIM_00642 2.5e-226 pbuG S permease
AKKDOMIM_00643 1.4e-37 S Putative adhesin
AKKDOMIM_00644 3.7e-261 V ABC transporter transmembrane region
AKKDOMIM_00645 1.1e-139
AKKDOMIM_00646 1.8e-31
AKKDOMIM_00649 8.1e-37
AKKDOMIM_00650 7.8e-56 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AKKDOMIM_00651 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
AKKDOMIM_00652 0.0 copA 3.6.3.54 P P-type ATPase
AKKDOMIM_00653 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
AKKDOMIM_00654 1.2e-105
AKKDOMIM_00655 7e-248 EGP Sugar (and other) transporter
AKKDOMIM_00656 1.2e-18
AKKDOMIM_00657 2.8e-210
AKKDOMIM_00658 3.5e-136 S SLAP domain
AKKDOMIM_00659 1.3e-117 S SLAP domain
AKKDOMIM_00660 1.1e-106 S Bacteriocin helveticin-J
AKKDOMIM_00661 5.7e-44
AKKDOMIM_00662 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00663 3.6e-33 E Zn peptidase
AKKDOMIM_00664 3.9e-287 clcA P chloride
AKKDOMIM_00665 3.1e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AKKDOMIM_00666 1.6e-31
AKKDOMIM_00667 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AKKDOMIM_00668 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AKKDOMIM_00669 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AKKDOMIM_00670 8.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AKKDOMIM_00671 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AKKDOMIM_00672 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
AKKDOMIM_00673 2e-199 L Transposase and inactivated derivatives, IS30 family
AKKDOMIM_00674 9.5e-245 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AKKDOMIM_00675 3.1e-185 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AKKDOMIM_00676 3.7e-174 L Bifunctional protein
AKKDOMIM_00677 2.6e-35 yaaA S S4 domain protein YaaA
AKKDOMIM_00678 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AKKDOMIM_00679 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AKKDOMIM_00680 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AKKDOMIM_00681 1.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
AKKDOMIM_00682 2.7e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AKKDOMIM_00683 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AKKDOMIM_00684 7.5e-85 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AKKDOMIM_00685 4.1e-259 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AKKDOMIM_00686 5.7e-69 rplI J Binds to the 23S rRNA
AKKDOMIM_00687 6.7e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AKKDOMIM_00688 2.3e-165 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
AKKDOMIM_00689 5.2e-170 degV S DegV family
AKKDOMIM_00690 2.5e-135 V ABC transporter transmembrane region
AKKDOMIM_00691 2.5e-166 scrK 2.7.1.2, 2.7.1.4 GK ROK family
AKKDOMIM_00693 1.4e-16
AKKDOMIM_00694 1.6e-227 I Protein of unknown function (DUF2974)
AKKDOMIM_00695 9.2e-119 yhiD S MgtC family
AKKDOMIM_00697 3.9e-131 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00698 7.4e-74
AKKDOMIM_00699 3.3e-87
AKKDOMIM_00700 3.3e-141 D Ftsk spoiiie family protein
AKKDOMIM_00701 5.1e-145 S Replication initiation factor
AKKDOMIM_00702 3.9e-55
AKKDOMIM_00703 2.3e-26
AKKDOMIM_00704 9.5e-220 L Belongs to the 'phage' integrase family
AKKDOMIM_00706 2.5e-62 yfiL V ABC transporter
AKKDOMIM_00707 2.9e-46 V Transport permease protein
AKKDOMIM_00708 3.4e-09
AKKDOMIM_00709 1.1e-68 sagB C Nitroreductase family
AKKDOMIM_00710 5.1e-56
AKKDOMIM_00711 1.8e-131 sagD S YcaO cyclodehydratase, ATP-ad Mg2+-binding
AKKDOMIM_00713 8.8e-29
AKKDOMIM_00716 4.9e-111 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00717 1.7e-47 K Helix-turn-helix domain
AKKDOMIM_00718 2.8e-27 L Transposase
AKKDOMIM_00719 1.5e-25 S CAAX protease self-immunity
AKKDOMIM_00720 1.4e-22 S CAAX protease self-immunity
AKKDOMIM_00721 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_00723 1.6e-96 ybaT E Amino acid permease
AKKDOMIM_00724 3.9e-07 S LPXTG cell wall anchor motif
AKKDOMIM_00725 2.6e-146 S Putative ABC-transporter type IV
AKKDOMIM_00727 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AKKDOMIM_00728 0.0 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AKKDOMIM_00729 5.2e-117 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
AKKDOMIM_00730 1.2e-210 oppA E ABC transporter substrate-binding protein
AKKDOMIM_00731 2.7e-109 oppA E ABC transporter substrate-binding protein
AKKDOMIM_00732 6.4e-177 K AI-2E family transporter
AKKDOMIM_00733 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
AKKDOMIM_00734 4.1e-18
AKKDOMIM_00735 5.2e-248 G Major Facilitator
AKKDOMIM_00736 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
AKKDOMIM_00737 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
AKKDOMIM_00738 1.7e-174 ABC-SBP S ABC transporter
AKKDOMIM_00739 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AKKDOMIM_00740 2e-155 P CorA-like Mg2+ transporter protein
AKKDOMIM_00741 1.2e-160 yvgN C Aldo keto reductase
AKKDOMIM_00742 0.0 tetP J elongation factor G
AKKDOMIM_00743 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
AKKDOMIM_00744 7.6e-134 EGP Major facilitator Superfamily
AKKDOMIM_00745 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AKKDOMIM_00748 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
AKKDOMIM_00749 1.3e-273 E amino acid
AKKDOMIM_00750 0.0 L Helicase C-terminal domain protein
AKKDOMIM_00751 4.8e-205 pbpX1 V Beta-lactamase
AKKDOMIM_00752 5.1e-226 N Uncharacterized conserved protein (DUF2075)
AKKDOMIM_00753 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
AKKDOMIM_00756 5.7e-166 psaA P Belongs to the bacterial solute-binding protein 9 family
AKKDOMIM_00759 8.7e-218 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AKKDOMIM_00760 2.4e-246 qacA EGP Major facilitator Superfamily
AKKDOMIM_00761 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
AKKDOMIM_00762 3.1e-151 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AKKDOMIM_00763 1.4e-183 yfeW 3.4.16.4 V Beta-lactamase
AKKDOMIM_00764 3.1e-187 S Bacterial protein of unknown function (DUF871)
AKKDOMIM_00765 4.5e-144 ybbH_2 K rpiR family
AKKDOMIM_00766 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
AKKDOMIM_00767 6.8e-235 L Transposase DDE domain
AKKDOMIM_00768 1.2e-238 cydA 1.10.3.14 C ubiquinol oxidase
AKKDOMIM_00769 2.5e-173 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
AKKDOMIM_00770 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
AKKDOMIM_00771 4.1e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AKKDOMIM_00772 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
AKKDOMIM_00773 6.1e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AKKDOMIM_00774 3.6e-160 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
AKKDOMIM_00775 1.2e-230 ndh 1.6.99.3 C NADH dehydrogenase
AKKDOMIM_00776 1.6e-43 1.3.5.4 C FAD binding domain
AKKDOMIM_00777 1.6e-85 3.6.4.12 S PD-(D/E)XK nuclease family transposase
AKKDOMIM_00778 2.6e-169 K LysR substrate binding domain
AKKDOMIM_00779 6.4e-122 3.6.1.27 I Acid phosphatase homologues
AKKDOMIM_00780 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AKKDOMIM_00781 6.8e-298 ytgP S Polysaccharide biosynthesis protein
AKKDOMIM_00782 4.3e-47 pspC KT PspC domain
AKKDOMIM_00784 1.6e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AKKDOMIM_00785 6.9e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AKKDOMIM_00786 7.9e-99 M ErfK YbiS YcfS YnhG
AKKDOMIM_00787 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
AKKDOMIM_00788 6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
AKKDOMIM_00789 3e-90 S PFAM Archaeal ATPase
AKKDOMIM_00790 5.1e-91 S PFAM Archaeal ATPase
AKKDOMIM_00791 7.7e-26
AKKDOMIM_00792 4.3e-76 menA 2.5.1.74 H UbiA prenyltransferase family
AKKDOMIM_00793 1.9e-75 M LysM domain
AKKDOMIM_00794 4.5e-43
AKKDOMIM_00797 3.5e-29
AKKDOMIM_00798 2.9e-73 yniG EGP Major facilitator Superfamily
AKKDOMIM_00799 9.2e-237 L transposase, IS605 OrfB family
AKKDOMIM_00800 4.7e-92 yniG EGP Major facilitator Superfamily
AKKDOMIM_00801 7.3e-184 S cog cog1373
AKKDOMIM_00802 5.6e-179 S PFAM Archaeal ATPase
AKKDOMIM_00803 1.8e-193 I transferase activity, transferring acyl groups other than amino-acyl groups
AKKDOMIM_00804 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
AKKDOMIM_00805 1.6e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AKKDOMIM_00806 2.9e-78 G Phosphoglycerate mutase family
AKKDOMIM_00807 8.9e-10 G Phosphoglycerate mutase family
AKKDOMIM_00808 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
AKKDOMIM_00809 6.5e-151 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AKKDOMIM_00810 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AKKDOMIM_00811 7.2e-56 yheA S Belongs to the UPF0342 family
AKKDOMIM_00812 1.5e-230 yhaO L Ser Thr phosphatase family protein
AKKDOMIM_00813 0.0 L AAA domain
AKKDOMIM_00814 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
AKKDOMIM_00815 2.9e-23
AKKDOMIM_00816 2.4e-51 S Domain of unknown function DUF1829
AKKDOMIM_00817 3.1e-265
AKKDOMIM_00818 1.5e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
AKKDOMIM_00819 1.5e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AKKDOMIM_00820 3.9e-25
AKKDOMIM_00821 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
AKKDOMIM_00822 1.7e-134 ecsA V ABC transporter, ATP-binding protein
AKKDOMIM_00823 2.9e-221 ecsB U ABC transporter
AKKDOMIM_00824 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AKKDOMIM_00825 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AKKDOMIM_00826 2.4e-121 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AKKDOMIM_00827 3.7e-185
AKKDOMIM_00828 6.1e-249 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AKKDOMIM_00829 1.5e-234 mepA V MATE efflux family protein
AKKDOMIM_00830 8.4e-171 S SLAP domain
AKKDOMIM_00831 7.4e-74 L Putative transposase DNA-binding domain
AKKDOMIM_00832 1.7e-84 L Putative transposase DNA-binding domain
AKKDOMIM_00833 1.4e-83 L Resolvase, N-terminal
AKKDOMIM_00834 1.2e-157 M Peptidase family M1 domain
AKKDOMIM_00835 2.7e-193 S Bacteriocin helveticin-J
AKKDOMIM_00836 1.6e-18
AKKDOMIM_00837 2.4e-50 L RelB antitoxin
AKKDOMIM_00838 9.1e-140 qmcA O prohibitin homologues
AKKDOMIM_00839 1.9e-199 purD 6.3.4.13 F Belongs to the GARS family
AKKDOMIM_00840 7.4e-150 fhaB M Rib/alpha-like repeat
AKKDOMIM_00841 6.8e-61 fhaB M Rib/alpha-like repeat
AKKDOMIM_00842 7.7e-22
AKKDOMIM_00843 9.3e-64 L PFAM IS66 Orf2 family protein
AKKDOMIM_00844 8.7e-34 S Transposase C of IS166 homeodomain
AKKDOMIM_00845 1.9e-245 L Transposase IS66 family
AKKDOMIM_00847 3.4e-164 msmX P Belongs to the ABC transporter superfamily
AKKDOMIM_00848 5e-226 L Transposase
AKKDOMIM_00849 3.8e-30
AKKDOMIM_00850 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AKKDOMIM_00851 9.4e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AKKDOMIM_00852 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AKKDOMIM_00853 3.9e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AKKDOMIM_00854 8.6e-251 dnaB L Replication initiation and membrane attachment
AKKDOMIM_00855 1.3e-168 dnaI L Primosomal protein DnaI
AKKDOMIM_00856 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AKKDOMIM_00857 4.3e-75
AKKDOMIM_00858 1.5e-222 L Transposase
AKKDOMIM_00859 1.5e-180 S Domain of unknown function (DUF389)
AKKDOMIM_00860 1.3e-96 L Transposase
AKKDOMIM_00861 3e-107 L Transposase
AKKDOMIM_00862 1.1e-100 potB E Binding-protein-dependent transport system inner membrane component
AKKDOMIM_00863 1.2e-97 rihB 3.2.2.1 F Nucleoside
AKKDOMIM_00864 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AKKDOMIM_00865 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AKKDOMIM_00866 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AKKDOMIM_00867 1.1e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AKKDOMIM_00868 8.6e-199 tnpB L Putative transposase DNA-binding domain
AKKDOMIM_00869 4.2e-84 yqeG S HAD phosphatase, family IIIA
AKKDOMIM_00870 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
AKKDOMIM_00871 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AKKDOMIM_00872 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
AKKDOMIM_00873 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AKKDOMIM_00874 4.6e-216 ylbM S Belongs to the UPF0348 family
AKKDOMIM_00875 4.7e-97 yceD S Uncharacterized ACR, COG1399
AKKDOMIM_00876 1.2e-126 K response regulator
AKKDOMIM_00877 1.3e-277 arlS 2.7.13.3 T Histidine kinase
AKKDOMIM_00878 1e-12
AKKDOMIM_00879 9.2e-100 S CAAX protease self-immunity
AKKDOMIM_00880 6.1e-224 S SLAP domain
AKKDOMIM_00881 1.3e-82 S Aminoacyl-tRNA editing domain
AKKDOMIM_00882 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AKKDOMIM_00883 2.4e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AKKDOMIM_00884 7.7e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKKDOMIM_00885 4.5e-58 yodB K Transcriptional regulator, HxlR family
AKKDOMIM_00887 2.7e-107 papP P ABC transporter, permease protein
AKKDOMIM_00888 5.3e-116 P ABC transporter permease
AKKDOMIM_00889 3.3e-127 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AKKDOMIM_00890 6.2e-157 cjaA ET ABC transporter substrate-binding protein
AKKDOMIM_00891 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AKKDOMIM_00892 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AKKDOMIM_00893 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AKKDOMIM_00894 3.7e-168 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
AKKDOMIM_00895 3.8e-136 metQ1 P Belongs to the nlpA lipoprotein family
AKKDOMIM_00896 1.9e-25
AKKDOMIM_00897 0.0 mco Q Multicopper oxidase
AKKDOMIM_00898 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
AKKDOMIM_00899 0.0 oppA E ABC transporter
AKKDOMIM_00900 3.4e-73 Q Imidazolonepropionase and related amidohydrolases
AKKDOMIM_00901 3.7e-148 Q Imidazolonepropionase and related amidohydrolases
AKKDOMIM_00902 1.4e-245 3.5.1.47 S Peptidase dimerisation domain
AKKDOMIM_00903 3e-137 S Protein of unknown function (DUF3100)
AKKDOMIM_00904 5.7e-46 S An automated process has identified a potential problem with this gene model
AKKDOMIM_00905 2.6e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
AKKDOMIM_00906 2.2e-113 S SLAP domain
AKKDOMIM_00907 4.6e-48 L Transposase
AKKDOMIM_00908 2.2e-89
AKKDOMIM_00909 1.1e-08 isdH M Iron Transport-associated domain
AKKDOMIM_00910 6.3e-123 M Iron Transport-associated domain
AKKDOMIM_00911 8.7e-159 isdE P Periplasmic binding protein
AKKDOMIM_00912 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AKKDOMIM_00913 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
AKKDOMIM_00914 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AKKDOMIM_00915 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
AKKDOMIM_00916 1.3e-38 S RelB antitoxin
AKKDOMIM_00917 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
AKKDOMIM_00918 0.0 S membrane
AKKDOMIM_00919 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
AKKDOMIM_00920 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AKKDOMIM_00921 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AKKDOMIM_00922 4e-119 gluP 3.4.21.105 S Rhomboid family
AKKDOMIM_00923 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
AKKDOMIM_00924 1.5e-65 yqhL P Rhodanese-like protein
AKKDOMIM_00925 1.5e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AKKDOMIM_00926 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
AKKDOMIM_00927 2e-263 glnA 6.3.1.2 E glutamine synthetase
AKKDOMIM_00928 6.7e-170
AKKDOMIM_00929 6e-148
AKKDOMIM_00930 1.9e-21
AKKDOMIM_00933 2.7e-34
AKKDOMIM_00934 1.2e-128 S interspecies interaction between organisms
AKKDOMIM_00936 9.1e-10 K peptidyl-tyrosine sulfation
AKKDOMIM_00937 7.1e-263 E ABC transporter, substratebinding protein
AKKDOMIM_00938 3.7e-66 K Helix-turn-helix domain, rpiR family
AKKDOMIM_00939 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
AKKDOMIM_00940 8.4e-90 nanK GK ROK family
AKKDOMIM_00941 3.1e-56 G Xylose isomerase domain protein TIM barrel
AKKDOMIM_00942 2.1e-120 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AKKDOMIM_00943 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AKKDOMIM_00944 1.3e-67 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
AKKDOMIM_00945 5.7e-24 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
AKKDOMIM_00946 7.7e-110 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
AKKDOMIM_00947 2.8e-125 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AKKDOMIM_00948 1.4e-107 yisY 1.11.1.10 S Alpha/beta hydrolase family
AKKDOMIM_00949 3.5e-108 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
AKKDOMIM_00950 6.1e-111 crt 4.2.1.17 I Enoyl-CoA hydratase/isomerase
AKKDOMIM_00951 9.3e-151 fabK 1.3.1.9 S Nitronate monooxygenase
AKKDOMIM_00952 1.6e-82 2.8.3.1 I Coenzyme A transferase
AKKDOMIM_00953 1.1e-149 2.8.3.1 I Coenzyme A transferase
AKKDOMIM_00954 3.7e-144 gltC_1 3.1.3.48 K LysR substrate binding domain
AKKDOMIM_00955 1.5e-54 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AKKDOMIM_00956 3.2e-75 S ECF transporter, substrate-specific component
AKKDOMIM_00958 9.3e-74 coaA 2.7.1.33 F Pantothenic acid kinase
AKKDOMIM_00959 1.4e-31 O OsmC-like protein
AKKDOMIM_00961 1.5e-36 oppA E ABC transporter substrate-binding protein
AKKDOMIM_00962 1.3e-34 L An automated process has identified a potential problem with this gene model
AKKDOMIM_00963 2.2e-54 oppA E ABC transporter substrate-binding protein
AKKDOMIM_00964 1.3e-149 oppA E ABC transporter substrate-binding protein
AKKDOMIM_00965 2.8e-14 L PFAM transposase, IS4 family protein
AKKDOMIM_00966 2.2e-102
AKKDOMIM_00968 7.4e-32 L COG2963 Transposase and inactivated derivatives
AKKDOMIM_00969 4e-60 L Resolvase, N terminal domain
AKKDOMIM_00970 4.6e-25 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AKKDOMIM_00971 2.3e-101 L An automated process has identified a potential problem with this gene model
AKKDOMIM_00972 1.8e-132 infB M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AKKDOMIM_00973 7.3e-07 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
AKKDOMIM_00974 6.5e-59 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
AKKDOMIM_00975 4.8e-27 L Transposase
AKKDOMIM_00976 7.4e-32 L COG2963 Transposase and inactivated derivatives
AKKDOMIM_00977 4.7e-188 K Periplasmic binding protein-like domain
AKKDOMIM_00978 2e-106 K Transcriptional regulator, AbiEi antitoxin
AKKDOMIM_00979 6.4e-162 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
AKKDOMIM_00980 4.5e-188 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AKKDOMIM_00981 7e-146 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
AKKDOMIM_00982 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
AKKDOMIM_00983 3.2e-165 lacR K Transcriptional regulator
AKKDOMIM_00984 0.0 lacS G Transporter
AKKDOMIM_00985 0.0 lacZ 3.2.1.23 G -beta-galactosidase
AKKDOMIM_00986 2.1e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AKKDOMIM_00987 2e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
AKKDOMIM_00988 2.2e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AKKDOMIM_00989 5.5e-36
AKKDOMIM_00990 1.6e-158 scrR K Periplasmic binding protein domain
AKKDOMIM_00991 2.3e-237 msmE G Bacterial extracellular solute-binding protein
AKKDOMIM_00992 4.8e-157 msmF P Binding-protein-dependent transport system inner membrane component
AKKDOMIM_00993 2e-152 msmG P Binding-protein-dependent transport system inner membrane component
AKKDOMIM_00994 2.8e-210 msmX P Belongs to the ABC transporter superfamily
AKKDOMIM_00995 1.3e-34 rafA 3.2.1.22 G alpha-galactosidase
AKKDOMIM_00996 0.0 rafA 3.2.1.22 G alpha-galactosidase
AKKDOMIM_00997 6.2e-271 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
AKKDOMIM_00998 7.5e-109 2.7.6.5 T Region found in RelA / SpoT proteins
AKKDOMIM_00999 6e-27 K response regulator
AKKDOMIM_01000 1.3e-65 K response regulator
AKKDOMIM_01001 2.5e-215 sptS 2.7.13.3 T Histidine kinase
AKKDOMIM_01002 6.7e-207 EGP Major facilitator Superfamily
AKKDOMIM_01003 5.6e-68 O OsmC-like protein
AKKDOMIM_01004 5.3e-84 S Protein of unknown function (DUF805)
AKKDOMIM_01005 3.2e-77
AKKDOMIM_01006 2.7e-285
AKKDOMIM_01007 2.8e-08 S Fic/DOC family
AKKDOMIM_01008 4.5e-49 S Fic/DOC family
AKKDOMIM_01009 3.2e-278 yjeM E Amino Acid
AKKDOMIM_01010 4.4e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AKKDOMIM_01011 5.4e-242 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
AKKDOMIM_01012 9.7e-136 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
AKKDOMIM_01013 1.2e-94 L Transposase
AKKDOMIM_01014 5.3e-163 L Transposase
AKKDOMIM_01015 3.3e-52 S Iron-sulfur cluster assembly protein
AKKDOMIM_01016 8.5e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
AKKDOMIM_01017 3.4e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
AKKDOMIM_01018 1.5e-43
AKKDOMIM_01019 2.7e-285 lsa S ABC transporter
AKKDOMIM_01020 1.9e-121 L Transposase
AKKDOMIM_01021 4.1e-86 L Transposase
AKKDOMIM_01022 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AKKDOMIM_01023 2e-37 scrR K Periplasmic binding protein domain
AKKDOMIM_01024 2.8e-33 scrR K Periplasmic binding protein domain
AKKDOMIM_01025 1.3e-30
AKKDOMIM_01026 8e-69 T Toxin-antitoxin system, toxin component, MazF family
AKKDOMIM_01027 2.2e-102 L Integrase
AKKDOMIM_01028 8.2e-154 L Transposase
AKKDOMIM_01029 4e-56 L Transposase
AKKDOMIM_01030 5.4e-106 L PFAM Integrase catalytic
AKKDOMIM_01031 2.5e-118 clcA P chloride
AKKDOMIM_01032 1.6e-60 clcA P chloride
AKKDOMIM_01033 4.7e-26 K FCD
AKKDOMIM_01035 9.8e-93 GM NmrA-like family
AKKDOMIM_01036 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AKKDOMIM_01037 3.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AKKDOMIM_01038 2.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AKKDOMIM_01039 4.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AKKDOMIM_01040 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AKKDOMIM_01041 4e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AKKDOMIM_01042 2.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AKKDOMIM_01043 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
AKKDOMIM_01044 3.5e-248 lctP C L-lactate permease
AKKDOMIM_01045 4e-148 glcU U sugar transport
AKKDOMIM_01046 7.1e-46
AKKDOMIM_01047 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
AKKDOMIM_01048 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AKKDOMIM_01049 1.1e-36 S Alpha beta hydrolase
AKKDOMIM_01050 2.3e-65 S Alpha beta hydrolase
AKKDOMIM_01051 1.9e-37
AKKDOMIM_01052 2.6e-52
AKKDOMIM_01053 4e-113 S haloacid dehalogenase-like hydrolase
AKKDOMIM_01054 2e-291 V ABC-type multidrug transport system, ATPase and permease components
AKKDOMIM_01055 4.1e-276 V ABC-type multidrug transport system, ATPase and permease components
AKKDOMIM_01056 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
AKKDOMIM_01057 2.9e-178 I Carboxylesterase family
AKKDOMIM_01059 1.7e-205 M Glycosyl hydrolases family 25
AKKDOMIM_01060 1.3e-157 cinI S Serine hydrolase (FSH1)
AKKDOMIM_01061 2.7e-300 S Predicted membrane protein (DUF2207)
AKKDOMIM_01062 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
AKKDOMIM_01065 3.3e-303 L Transposase
AKKDOMIM_01066 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
AKKDOMIM_01067 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AKKDOMIM_01068 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
AKKDOMIM_01069 7.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AKKDOMIM_01070 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AKKDOMIM_01071 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AKKDOMIM_01072 1.7e-70 yqhY S Asp23 family, cell envelope-related function
AKKDOMIM_01073 2.1e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AKKDOMIM_01074 2.2e-143 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AKKDOMIM_01075 7.6e-186 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AKKDOMIM_01076 1.1e-34 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AKKDOMIM_01077 2.4e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AKKDOMIM_01078 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AKKDOMIM_01079 8.8e-293 recN L May be involved in recombinational repair of damaged DNA
AKKDOMIM_01080 1.1e-77 6.3.3.2 S ASCH
AKKDOMIM_01081 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
AKKDOMIM_01082 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AKKDOMIM_01083 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AKKDOMIM_01084 1.6e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AKKDOMIM_01085 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AKKDOMIM_01086 1.3e-139 stp 3.1.3.16 T phosphatase
AKKDOMIM_01087 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
AKKDOMIM_01088 4.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AKKDOMIM_01089 1.7e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AKKDOMIM_01090 2.4e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
AKKDOMIM_01091 1.1e-30
AKKDOMIM_01092 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AKKDOMIM_01093 4e-57 asp S Asp23 family, cell envelope-related function
AKKDOMIM_01094 2e-305 yloV S DAK2 domain fusion protein YloV
AKKDOMIM_01095 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AKKDOMIM_01096 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AKKDOMIM_01097 9.8e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AKKDOMIM_01098 9.6e-194 oppD P Belongs to the ABC transporter superfamily
AKKDOMIM_01099 1.9e-170 oppF P Belongs to the ABC transporter superfamily
AKKDOMIM_01100 5.7e-172 oppB P ABC transporter permease
AKKDOMIM_01101 1.7e-128 oppC P Binding-protein-dependent transport system inner membrane component
AKKDOMIM_01102 7.4e-120 oppA E ABC transporter substrate-binding protein
AKKDOMIM_01103 1.8e-116 oppA E ABC transporter substrate-binding protein
AKKDOMIM_01104 2.4e-15 oppA E ABC transporter substrate-binding protein
AKKDOMIM_01105 3e-307 oppA E ABC transporter substrate-binding protein
AKKDOMIM_01106 5.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AKKDOMIM_01107 0.0 smc D Required for chromosome condensation and partitioning
AKKDOMIM_01108 7e-162 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AKKDOMIM_01109 2.5e-288 pipD E Dipeptidase
AKKDOMIM_01111 3.4e-23
AKKDOMIM_01112 4.1e-133 cysA V ABC transporter, ATP-binding protein
AKKDOMIM_01113 0.0 V FtsX-like permease family
AKKDOMIM_01114 4.1e-259 yfnA E amino acid
AKKDOMIM_01115 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AKKDOMIM_01116 1.7e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AKKDOMIM_01117 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AKKDOMIM_01118 1.7e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AKKDOMIM_01119 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AKKDOMIM_01120 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AKKDOMIM_01121 6.7e-212 S SLAP domain
AKKDOMIM_01122 2.1e-120 ung2 3.2.2.27 L Uracil-DNA glycosylase
AKKDOMIM_01123 1.3e-114 E GDSL-like Lipase/Acylhydrolase family
AKKDOMIM_01124 9.5e-112 L Resolvase, N-terminal
AKKDOMIM_01125 7.7e-204 L Putative transposase DNA-binding domain
AKKDOMIM_01126 1.4e-20 E GDSL-like Lipase/Acylhydrolase family
AKKDOMIM_01127 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AKKDOMIM_01128 3e-38 ynzC S UPF0291 protein
AKKDOMIM_01129 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
AKKDOMIM_01130 0.0 mdlA V ABC transporter
AKKDOMIM_01131 0.0 mdlB V ABC transporter
AKKDOMIM_01132 0.0 pepO 3.4.24.71 O Peptidase family M13
AKKDOMIM_01133 4e-220 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
AKKDOMIM_01134 2.9e-116 plsC 2.3.1.51 I Acyltransferase
AKKDOMIM_01135 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
AKKDOMIM_01136 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
AKKDOMIM_01137 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AKKDOMIM_01138 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AKKDOMIM_01139 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AKKDOMIM_01140 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AKKDOMIM_01141 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
AKKDOMIM_01142 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AKKDOMIM_01143 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AKKDOMIM_01144 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AKKDOMIM_01145 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
AKKDOMIM_01146 1.4e-196 nusA K Participates in both transcription termination and antitermination
AKKDOMIM_01147 8.8e-47 ylxR K Protein of unknown function (DUF448)
AKKDOMIM_01148 3.2e-47 rplGA J ribosomal protein
AKKDOMIM_01149 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AKKDOMIM_01150 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AKKDOMIM_01151 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AKKDOMIM_01152 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AKKDOMIM_01153 4.5e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AKKDOMIM_01154 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AKKDOMIM_01155 0.0 dnaK O Heat shock 70 kDa protein
AKKDOMIM_01156 5.8e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AKKDOMIM_01157 4.2e-180 sip L Belongs to the 'phage' integrase family
AKKDOMIM_01158 1.6e-20 S YjcQ protein
AKKDOMIM_01162 6e-14
AKKDOMIM_01163 1.2e-10 E Zn peptidase
AKKDOMIM_01164 3.5e-15 ansR 3.4.21.88 K Cro/C1-type HTH DNA-binding domain
AKKDOMIM_01165 1.1e-12
AKKDOMIM_01166 1.8e-10
AKKDOMIM_01167 2.1e-76 S Phage antirepressor protein KilAC domain
AKKDOMIM_01172 2.9e-12
AKKDOMIM_01173 8e-97 S AntA/AntB antirepressor
AKKDOMIM_01178 3.6e-09
AKKDOMIM_01183 6.9e-59 S Protein of unknown function (DUF1071)
AKKDOMIM_01184 6.8e-33 S Conserved phage C-terminus (Phg_2220_C)
AKKDOMIM_01185 1.4e-51 dnaC L IstB-like ATP binding protein
AKKDOMIM_01191 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
AKKDOMIM_01192 2.1e-14
AKKDOMIM_01199 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
AKKDOMIM_01200 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
AKKDOMIM_01201 2.7e-25 L Terminase small subunit
AKKDOMIM_01202 9.8e-232 S Terminase-like family
AKKDOMIM_01203 6.3e-143 S Protein of unknown function (DUF1073)
AKKDOMIM_01204 2e-98 S Phage Mu protein F like protein
AKKDOMIM_01205 1.1e-07 S Lysin motif
AKKDOMIM_01206 3.9e-87 S Uncharacterized protein conserved in bacteria (DUF2213)
AKKDOMIM_01207 8.2e-60
AKKDOMIM_01208 7.1e-143 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
AKKDOMIM_01209 3.2e-31 S Protein of unknown function (DUF4054)
AKKDOMIM_01210 6.8e-76
AKKDOMIM_01211 1.5e-44
AKKDOMIM_01212 1.2e-55
AKKDOMIM_01213 5.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
AKKDOMIM_01214 4e-56
AKKDOMIM_01215 6.9e-27
AKKDOMIM_01217 0.0 3.4.14.13 M Phage tail tape measure protein TP901
AKKDOMIM_01218 6.7e-54 M LysM domain
AKKDOMIM_01219 2.1e-46
AKKDOMIM_01220 1.1e-104
AKKDOMIM_01221 1.2e-48
AKKDOMIM_01222 4.3e-33
AKKDOMIM_01223 8.5e-125 Z012_12235 S Baseplate J-like protein
AKKDOMIM_01224 2.9e-09
AKKDOMIM_01225 1.9e-36
AKKDOMIM_01229 4.2e-38
AKKDOMIM_01230 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
AKKDOMIM_01231 1.1e-07
AKKDOMIM_01233 7.9e-19
AKKDOMIM_01234 5e-29
AKKDOMIM_01235 6.7e-172 M Glycosyl hydrolases family 25
AKKDOMIM_01236 5.9e-24
AKKDOMIM_01237 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
AKKDOMIM_01238 4.5e-101 srtA 3.4.22.70 M sortase family
AKKDOMIM_01239 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
AKKDOMIM_01240 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AKKDOMIM_01241 1.2e-210 S Bacterial protein of unknown function (DUF871)
AKKDOMIM_01243 2.3e-43 ybhL S Belongs to the BI1 family
AKKDOMIM_01244 1e-48 S Metal binding domain of Ada
AKKDOMIM_01245 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
AKKDOMIM_01246 1.2e-136 lysR5 K LysR substrate binding domain
AKKDOMIM_01247 8.8e-234 arcA 3.5.3.6 E Arginine
AKKDOMIM_01248 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AKKDOMIM_01249 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
AKKDOMIM_01250 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
AKKDOMIM_01251 2.3e-215 S Sterol carrier protein domain
AKKDOMIM_01252 1e-20
AKKDOMIM_01253 2.4e-107 K LysR substrate binding domain
AKKDOMIM_01254 9e-98
AKKDOMIM_01255 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
AKKDOMIM_01256 1.4e-94
AKKDOMIM_01257 3e-96 L Transposase
AKKDOMIM_01258 8.9e-276 V ABC-type multidrug transport system, ATPase and permease components
AKKDOMIM_01259 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
AKKDOMIM_01260 3.4e-27
AKKDOMIM_01261 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
AKKDOMIM_01262 5.4e-53 hipB K sequence-specific DNA binding
AKKDOMIM_01263 4.8e-42 S SnoaL-like domain
AKKDOMIM_01264 0.0 L PLD-like domain
AKKDOMIM_01265 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
AKKDOMIM_01266 8.8e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
AKKDOMIM_01267 2.6e-280 thrC 4.2.3.1 E Threonine synthase
AKKDOMIM_01268 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AKKDOMIM_01269 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AKKDOMIM_01270 2.5e-118
AKKDOMIM_01271 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AKKDOMIM_01273 2.3e-08 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AKKDOMIM_01274 3.1e-122 L Belongs to the 'phage' integrase family
AKKDOMIM_01275 1.6e-180 V Abi-like protein
AKKDOMIM_01278 2.5e-30 S Hypothetical protein (DUF2513)
AKKDOMIM_01279 6.2e-74 3.4.21.88 K Peptidase S24-like
AKKDOMIM_01280 2.3e-10 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_01288 1.1e-20 L Psort location Cytoplasmic, score
AKKDOMIM_01291 1.3e-09
AKKDOMIM_01292 1.1e-24 S HNH endonuclease
AKKDOMIM_01297 1e-83 ps308 K AntA/AntB antirepressor
AKKDOMIM_01303 1.1e-08
AKKDOMIM_01304 7.8e-62 L HNH nucleases
AKKDOMIM_01305 9.3e-56 L Phage terminase, small subunit
AKKDOMIM_01308 1.8e-217 S Phage Terminase
AKKDOMIM_01310 2.7e-16 S Phage portal protein
AKKDOMIM_01311 3.3e-127 L PFAM transposase IS116 IS110 IS902
AKKDOMIM_01312 7e-83 S Phage portal protein
AKKDOMIM_01313 1.4e-74 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
AKKDOMIM_01314 3.5e-50 S peptidase activity
AKKDOMIM_01315 7.3e-17 S Phage gp6-like head-tail connector protein
AKKDOMIM_01317 4.1e-23 S Bacteriophage HK97-gp10, putative tail-component
AKKDOMIM_01318 8.1e-13 S Protein of unknown function (DUF806)
AKKDOMIM_01319 1e-25 S Phage tail tube protein
AKKDOMIM_01322 7e-158 M Phage tail tape measure protein TP901
AKKDOMIM_01323 1.1e-37 S phage tail
AKKDOMIM_01324 2.3e-49 S Phage minor structural protein
AKKDOMIM_01325 8.9e-113 S Phage minor structural protein
AKKDOMIM_01328 6.4e-55 E GDSL-like Lipase/Acylhydrolase
AKKDOMIM_01332 2.2e-69 lysA2 M Glycosyl hydrolases family 25
AKKDOMIM_01333 1e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AKKDOMIM_01334 2e-117 S Peptidase family M23
AKKDOMIM_01335 1.7e-82 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AKKDOMIM_01336 5.1e-181 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
AKKDOMIM_01337 3e-130 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AKKDOMIM_01338 8.3e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AKKDOMIM_01339 4e-40 S CRISPR-associated protein (Cas_Csn2)
AKKDOMIM_01340 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
AKKDOMIM_01341 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AKKDOMIM_01342 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AKKDOMIM_01343 3.5e-71 yqeY S YqeY-like protein
AKKDOMIM_01344 2.5e-175 phoH T phosphate starvation-inducible protein PhoH
AKKDOMIM_01345 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AKKDOMIM_01346 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AKKDOMIM_01347 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
AKKDOMIM_01348 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AKKDOMIM_01349 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AKKDOMIM_01350 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AKKDOMIM_01351 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AKKDOMIM_01352 1.4e-127 S Peptidase family M23
AKKDOMIM_01353 4.8e-81 mutT 3.6.1.55 F NUDIX domain
AKKDOMIM_01354 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
AKKDOMIM_01355 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AKKDOMIM_01356 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AKKDOMIM_01357 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
AKKDOMIM_01358 2.8e-123 skfE V ATPases associated with a variety of cellular activities
AKKDOMIM_01359 4.5e-141
AKKDOMIM_01360 5.1e-137
AKKDOMIM_01361 6.7e-145
AKKDOMIM_01362 1.4e-26
AKKDOMIM_01363 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AKKDOMIM_01364 7.5e-143
AKKDOMIM_01365 9.7e-169
AKKDOMIM_01366 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
AKKDOMIM_01367 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
AKKDOMIM_01368 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AKKDOMIM_01369 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
AKKDOMIM_01370 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AKKDOMIM_01371 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
AKKDOMIM_01372 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
AKKDOMIM_01373 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AKKDOMIM_01374 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AKKDOMIM_01375 9.2e-89 ypmB S Protein conserved in bacteria
AKKDOMIM_01376 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
AKKDOMIM_01377 1.3e-114 dnaD L DnaD domain protein
AKKDOMIM_01378 6.1e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AKKDOMIM_01379 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
AKKDOMIM_01380 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AKKDOMIM_01381 1e-107 ypsA S Belongs to the UPF0398 family
AKKDOMIM_01382 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AKKDOMIM_01383 1.5e-13 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AKKDOMIM_01384 1.6e-182 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AKKDOMIM_01385 1e-242 cpdA S Calcineurin-like phosphoesterase
AKKDOMIM_01386 3.4e-79
AKKDOMIM_01387 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
AKKDOMIM_01388 1.4e-34
AKKDOMIM_01389 3.6e-63
AKKDOMIM_01392 4.9e-118
AKKDOMIM_01393 3.8e-104 pncA Q Isochorismatase family
AKKDOMIM_01395 2e-35
AKKDOMIM_01396 0.0 snf 2.7.11.1 KL domain protein
AKKDOMIM_01397 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AKKDOMIM_01398 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AKKDOMIM_01399 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AKKDOMIM_01400 5.6e-183 K Transcriptional regulator
AKKDOMIM_01401 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
AKKDOMIM_01402 2.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AKKDOMIM_01403 2.7e-123 yoaK S Protein of unknown function (DUF1275)
AKKDOMIM_01404 2e-39 S Transglycosylase associated protein
AKKDOMIM_01405 1.5e-211 M Glycosyl hydrolases family 25
AKKDOMIM_01406 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
AKKDOMIM_01407 4.1e-67
AKKDOMIM_01408 5.4e-203 xerS L Belongs to the 'phage' integrase family
AKKDOMIM_01409 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AKKDOMIM_01410 1.3e-159 degV S EDD domain protein, DegV family
AKKDOMIM_01411 1.1e-66
AKKDOMIM_01412 0.0 FbpA K Fibronectin-binding protein
AKKDOMIM_01413 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
AKKDOMIM_01414 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AKKDOMIM_01415 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AKKDOMIM_01416 1.4e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AKKDOMIM_01417 2.3e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AKKDOMIM_01418 5.5e-53
AKKDOMIM_01420 2.7e-34 S YSIRK type signal peptide
AKKDOMIM_01421 1.9e-110 F DNA/RNA non-specific endonuclease
AKKDOMIM_01422 2e-75 S cog cog0433
AKKDOMIM_01423 3.2e-10 S Domain of unknown function DUF87
AKKDOMIM_01424 1.2e-63 S SIR2-like domain
AKKDOMIM_01425 1.7e-98 3.1.21.3 V Type I restriction modification DNA specificity domain
AKKDOMIM_01426 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
AKKDOMIM_01427 3.4e-42 S RloB-like protein
AKKDOMIM_01428 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
AKKDOMIM_01429 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
AKKDOMIM_01430 0.0 S SLAP domain
AKKDOMIM_01432 1.2e-235 XK27_01810 S Calcineurin-like phosphoesterase
AKKDOMIM_01433 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
AKKDOMIM_01434 1.5e-239 G Bacterial extracellular solute-binding protein
AKKDOMIM_01435 5.7e-18
AKKDOMIM_01436 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
AKKDOMIM_01437 8.9e-101 treR K UTRA
AKKDOMIM_01438 7.3e-283 treB G phosphotransferase system
AKKDOMIM_01439 5.7e-65 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AKKDOMIM_01440 4.7e-190 yrvN L AAA C-terminal domain
AKKDOMIM_01441 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AKKDOMIM_01442 9e-83 K Acetyltransferase (GNAT) domain
AKKDOMIM_01443 1.3e-229 S Putative peptidoglycan binding domain
AKKDOMIM_01444 7.5e-95 S ECF-type riboflavin transporter, S component
AKKDOMIM_01445 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
AKKDOMIM_01446 9.3e-204 pbpX1 V Beta-lactamase
AKKDOMIM_01447 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
AKKDOMIM_01448 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AKKDOMIM_01449 2.1e-114 3.6.1.27 I Acid phosphatase homologues
AKKDOMIM_01450 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
AKKDOMIM_01451 0.0 uvrA3 L excinuclease ABC, A subunit
AKKDOMIM_01452 9.9e-82 C Flavodoxin
AKKDOMIM_01453 3e-88 L PFAM transposase, IS4 family protein
AKKDOMIM_01454 4.5e-24 L PFAM transposase, IS4 family protein
AKKDOMIM_01455 1.2e-66 L PFAM transposase, IS4 family protein
AKKDOMIM_01456 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
AKKDOMIM_01457 5.1e-245 ynbB 4.4.1.1 P aluminum resistance
AKKDOMIM_01458 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
AKKDOMIM_01459 3.2e-283 E Amino acid permease
AKKDOMIM_01460 1.6e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
AKKDOMIM_01461 1.2e-271 pepV 3.5.1.18 E dipeptidase PepV
AKKDOMIM_01462 1.4e-115 mmuP E amino acid
AKKDOMIM_01463 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
AKKDOMIM_01464 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AKKDOMIM_01465 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AKKDOMIM_01466 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
AKKDOMIM_01467 1.4e-98 L Helix-turn-helix domain
AKKDOMIM_01468 5.3e-139 L hmm pf00665
AKKDOMIM_01469 9.3e-136 UW LPXTG-motif cell wall anchor domain protein
AKKDOMIM_01470 9.3e-196 UW LPXTG-motif cell wall anchor domain protein
AKKDOMIM_01471 9.6e-45 UW LPXTG-motif cell wall anchor domain protein
AKKDOMIM_01472 1.1e-19 UW LPXTG-motif cell wall anchor domain protein
AKKDOMIM_01473 1.8e-237 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AKKDOMIM_01474 1.7e-99 J Acetyltransferase (GNAT) domain
AKKDOMIM_01475 1.4e-110 yjbF S SNARE associated Golgi protein
AKKDOMIM_01476 2.2e-67 S cog cog1373
AKKDOMIM_01477 6.2e-93 F Nucleoside 2-deoxyribosyltransferase
AKKDOMIM_01479 1.1e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
AKKDOMIM_01480 3.4e-107
AKKDOMIM_01481 0.0 ydgH S MMPL family
AKKDOMIM_01482 1.5e-98 yobS K Bacterial regulatory proteins, tetR family
AKKDOMIM_01483 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
AKKDOMIM_01484 1.8e-154 corA P CorA-like Mg2+ transporter protein
AKKDOMIM_01485 5.1e-240 G Bacterial extracellular solute-binding protein
AKKDOMIM_01486 2.4e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
AKKDOMIM_01487 6.1e-146 gtsC P Binding-protein-dependent transport system inner membrane component
AKKDOMIM_01488 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
AKKDOMIM_01489 9.3e-203 malK P ATPases associated with a variety of cellular activities
AKKDOMIM_01490 1.6e-282 pipD E Dipeptidase
AKKDOMIM_01491 1.9e-158 endA F DNA RNA non-specific endonuclease
AKKDOMIM_01492 1e-181 dnaQ 2.7.7.7 L EXOIII
AKKDOMIM_01493 5.8e-157 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AKKDOMIM_01494 3e-116 yviA S Protein of unknown function (DUF421)
AKKDOMIM_01495 1.1e-56 S Protein of unknown function (DUF3290)
AKKDOMIM_01496 3.7e-27 L Transposase
AKKDOMIM_01498 9.5e-115 pnuC H nicotinamide mononucleotide transporter
AKKDOMIM_01499 1.5e-41 L COG3547 Transposase and inactivated derivatives
AKKDOMIM_01500 4e-08
AKKDOMIM_01501 6.6e-56
AKKDOMIM_01502 2.7e-57
AKKDOMIM_01503 1.6e-11
AKKDOMIM_01504 1.5e-124 S PAS domain
AKKDOMIM_01505 2.9e-277 V ABC transporter transmembrane region
AKKDOMIM_01506 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
AKKDOMIM_01507 3.1e-130 T Transcriptional regulatory protein, C terminal
AKKDOMIM_01508 5.2e-187 T GHKL domain
AKKDOMIM_01509 5.8e-76 S Peptidase propeptide and YPEB domain
AKKDOMIM_01510 2.5e-72 S Peptidase propeptide and YPEB domain
AKKDOMIM_01511 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
AKKDOMIM_01512 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
AKKDOMIM_01513 7e-68 V ABC transporter transmembrane region
AKKDOMIM_01514 9e-161 V ABC transporter transmembrane region
AKKDOMIM_01515 2.3e-309 oppA3 E ABC transporter, substratebinding protein
AKKDOMIM_01516 2.4e-60 ypaA S Protein of unknown function (DUF1304)
AKKDOMIM_01517 2.1e-28 S Peptidase propeptide and YPEB domain
AKKDOMIM_01518 6.6e-235 L transposase, IS605 OrfB family
AKKDOMIM_01519 3e-112 L PFAM transposase IS116 IS110 IS902
AKKDOMIM_01520 8.8e-58 S Peptidase propeptide and YPEB domain
AKKDOMIM_01521 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AKKDOMIM_01522 7.4e-169 coaA 2.7.1.33 F Pantothenic acid kinase
AKKDOMIM_01523 7.9e-97 E GDSL-like Lipase/Acylhydrolase
AKKDOMIM_01524 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
AKKDOMIM_01525 1.6e-143 aatB ET ABC transporter substrate-binding protein
AKKDOMIM_01526 1e-105 glnQ 3.6.3.21 E ABC transporter
AKKDOMIM_01527 1.5e-107 glnP P ABC transporter permease
AKKDOMIM_01528 0.0 helD 3.6.4.12 L DNA helicase
AKKDOMIM_01529 2.3e-116 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
AKKDOMIM_01530 1.4e-126 pgm3 G Phosphoglycerate mutase family
AKKDOMIM_01531 1.2e-241 S response to antibiotic
AKKDOMIM_01532 3.2e-124
AKKDOMIM_01533 0.0 3.6.3.8 P P-type ATPase
AKKDOMIM_01534 4.3e-65 2.7.1.191 G PTS system fructose IIA component
AKKDOMIM_01535 4.4e-43
AKKDOMIM_01536 5.9e-09
AKKDOMIM_01537 1.5e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
AKKDOMIM_01538 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
AKKDOMIM_01539 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
AKKDOMIM_01540 1.5e-152
AKKDOMIM_01541 3e-24
AKKDOMIM_01542 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AKKDOMIM_01543 1.8e-104 3.2.2.20 K acetyltransferase
AKKDOMIM_01545 1.2e-225 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKKDOMIM_01546 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
AKKDOMIM_01547 2.2e-101 K Helix-turn-helix domain, rpiR family
AKKDOMIM_01548 1.1e-66 L Transposase and inactivated derivatives, IS30 family
AKKDOMIM_01549 0.0 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
AKKDOMIM_01550 6.2e-36 licR 2.7.1.200, 2.7.1.202 G Mga helix-turn-helix domain
AKKDOMIM_01551 7.4e-32 L COG2963 Transposase and inactivated derivatives
AKKDOMIM_01552 3.8e-93 licR 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT domain protein
AKKDOMIM_01553 1.5e-54 ybgG 3.2.1.170 GH38 G PFAM Glycosyl hydrolases family 38 C-terminal domain
AKKDOMIM_01554 2e-82 M Glycosyltransferase
AKKDOMIM_01555 9.1e-121 rfbP M Bacterial sugar transferase
AKKDOMIM_01556 3.7e-145 ywqE 3.1.3.48 GM PHP domain protein
AKKDOMIM_01557 5.8e-122 ywqD 2.7.10.1 D Capsular exopolysaccharide family
AKKDOMIM_01558 3.6e-144 epsB M biosynthesis protein
AKKDOMIM_01559 1.7e-177 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AKKDOMIM_01560 5.1e-13 L DDE superfamily endonuclease
AKKDOMIM_01561 2.2e-157 L DDE superfamily endonuclease
AKKDOMIM_01563 1.7e-29 S Predicted membrane protein (DUF2335)
AKKDOMIM_01565 1.5e-215 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AKKDOMIM_01566 3.5e-175 S Cysteine-rich secretory protein family
AKKDOMIM_01567 3.5e-41
AKKDOMIM_01568 2.6e-118 M NlpC/P60 family
AKKDOMIM_01569 1.4e-136 M NlpC P60 family protein
AKKDOMIM_01570 2e-89 M NlpC/P60 family
AKKDOMIM_01571 7.7e-89 gmk2 2.7.4.8 F Guanylate kinase homologues.
AKKDOMIM_01572 3.9e-42
AKKDOMIM_01573 6.5e-279 S O-antigen ligase like membrane protein
AKKDOMIM_01574 3.3e-112
AKKDOMIM_01575 2.3e-223 tnpB L Putative transposase DNA-binding domain
AKKDOMIM_01576 5.5e-77 nrdI F NrdI Flavodoxin like
AKKDOMIM_01577 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AKKDOMIM_01578 5.6e-68
AKKDOMIM_01579 2.7e-134 yvpB S Peptidase_C39 like family
AKKDOMIM_01580 1.1e-83 S Threonine/Serine exporter, ThrE
AKKDOMIM_01581 2.4e-136 thrE S Putative threonine/serine exporter
AKKDOMIM_01582 8.9e-292 S ABC transporter
AKKDOMIM_01583 8.3e-58
AKKDOMIM_01584 1.2e-97 rimL J Acetyltransferase (GNAT) domain
AKKDOMIM_01585 5.6e-19
AKKDOMIM_01586 8.2e-61
AKKDOMIM_01587 6.5e-125 S Protein of unknown function (DUF554)
AKKDOMIM_01588 2.2e-208 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AKKDOMIM_01589 0.0 pepF E oligoendopeptidase F
AKKDOMIM_01590 7.4e-40 S Enterocin A Immunity
AKKDOMIM_01591 3e-134 S CAAX amino terminal protease
AKKDOMIM_01595 5e-47 2.4.1.33 V HlyD family secretion protein
AKKDOMIM_01596 1.3e-34 L An automated process has identified a potential problem with this gene model
AKKDOMIM_01597 1.2e-304 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AKKDOMIM_01598 2.9e-79 K LytTr DNA-binding domain
AKKDOMIM_01599 1.4e-78 2.7.13.3 T GHKL domain
AKKDOMIM_01602 2e-25 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_01603 1.2e-11
AKKDOMIM_01604 5.4e-214 2.1.1.14 E methionine synthase, vitamin-B12 independent
AKKDOMIM_01605 6.1e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AKKDOMIM_01606 1.1e-08 S CAAX amino terminal protease
AKKDOMIM_01607 2.1e-24 L Transposase
AKKDOMIM_01608 8e-185 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
AKKDOMIM_01609 2.6e-115 dedA S SNARE-like domain protein
AKKDOMIM_01610 3.7e-100 S Protein of unknown function (DUF1461)
AKKDOMIM_01611 6.9e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AKKDOMIM_01612 1.7e-105 yutD S Protein of unknown function (DUF1027)
AKKDOMIM_01613 9.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
AKKDOMIM_01614 4.3e-55
AKKDOMIM_01615 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AKKDOMIM_01616 3.2e-181 ccpA K catabolite control protein A
AKKDOMIM_01617 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
AKKDOMIM_01618 5.8e-100 L Helix-turn-helix domain
AKKDOMIM_01619 2.4e-159 L hmm pf00665
AKKDOMIM_01620 1.3e-36
AKKDOMIM_01621 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AKKDOMIM_01622 1.3e-146 ykuT M mechanosensitive ion channel
AKKDOMIM_01623 3.1e-100 V ATPases associated with a variety of cellular activities
AKKDOMIM_01624 1.4e-133
AKKDOMIM_01625 3.4e-99
AKKDOMIM_01626 8.7e-19 spaC2 V Lanthionine synthetase C-like protein
AKKDOMIM_01629 4.4e-40 ropB K Helix-turn-helix domain
AKKDOMIM_01630 6.2e-111 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AKKDOMIM_01631 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AKKDOMIM_01632 1.1e-71 yslB S Protein of unknown function (DUF2507)
AKKDOMIM_01633 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AKKDOMIM_01634 3.5e-54 trxA O Belongs to the thioredoxin family
AKKDOMIM_01635 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AKKDOMIM_01636 1.1e-50 yrzB S Belongs to the UPF0473 family
AKKDOMIM_01637 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AKKDOMIM_01638 2e-42 yrzL S Belongs to the UPF0297 family
AKKDOMIM_01639 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AKKDOMIM_01640 4.7e-228 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AKKDOMIM_01641 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
AKKDOMIM_01642 5.9e-216 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AKKDOMIM_01643 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AKKDOMIM_01644 9.6e-41 yajC U Preprotein translocase
AKKDOMIM_01645 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AKKDOMIM_01646 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AKKDOMIM_01647 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AKKDOMIM_01648 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AKKDOMIM_01649 2.6e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AKKDOMIM_01650 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AKKDOMIM_01651 3.5e-75
AKKDOMIM_01652 2.3e-181 M CHAP domain
AKKDOMIM_01653 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
AKKDOMIM_01654 3.7e-295 scrB 3.2.1.26 GH32 G invertase
AKKDOMIM_01655 1.1e-183 scrR K helix_turn _helix lactose operon repressor
AKKDOMIM_01656 3.8e-176 L COG3547 Transposase and inactivated derivatives
AKKDOMIM_01657 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AKKDOMIM_01658 0.0 uup S ABC transporter, ATP-binding protein
AKKDOMIM_01659 5.3e-285 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
AKKDOMIM_01660 3.2e-170 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
AKKDOMIM_01661 1.3e-51 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
AKKDOMIM_01662 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AKKDOMIM_01663 4.8e-96 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
AKKDOMIM_01664 8.2e-134 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
AKKDOMIM_01665 2.2e-85 S ECF transporter, substrate-specific component
AKKDOMIM_01666 2.1e-129 fat 3.1.2.21 I Acyl-ACP thioesterase
AKKDOMIM_01667 1.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AKKDOMIM_01668 1.8e-59 yabA L Involved in initiation control of chromosome replication
AKKDOMIM_01669 3.7e-154 holB 2.7.7.7 L DNA polymerase III
AKKDOMIM_01670 2.2e-51 yaaQ S Cyclic-di-AMP receptor
AKKDOMIM_01671 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AKKDOMIM_01672 1.1e-34 S Protein of unknown function (DUF2508)
AKKDOMIM_01673 2.4e-107 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AKKDOMIM_01674 2.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AKKDOMIM_01675 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
AKKDOMIM_01676 5.7e-106 2.4.1.58 GT8 M family 8
AKKDOMIM_01677 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AKKDOMIM_01678 1.3e-84 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AKKDOMIM_01679 4.1e-225 L COG3385 FOG Transposase and inactivated derivatives
AKKDOMIM_01680 9e-26
AKKDOMIM_01681 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
AKKDOMIM_01682 5.1e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
AKKDOMIM_01683 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AKKDOMIM_01684 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AKKDOMIM_01685 3.3e-11 GT2,GT4 M family 8
AKKDOMIM_01686 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
AKKDOMIM_01687 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AKKDOMIM_01688 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AKKDOMIM_01689 1e-154 pstA P Phosphate transport system permease protein PstA
AKKDOMIM_01690 4.3e-162 pstC P probably responsible for the translocation of the substrate across the membrane
AKKDOMIM_01691 2.8e-157 pstS P Phosphate
AKKDOMIM_01692 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AKKDOMIM_01693 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AKKDOMIM_01694 3.1e-101 nusG K Participates in transcription elongation, termination and antitermination
AKKDOMIM_01695 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AKKDOMIM_01696 1.6e-246 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AKKDOMIM_01697 2.1e-70 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AKKDOMIM_01698 1.9e-286 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
AKKDOMIM_01699 1.7e-34
AKKDOMIM_01700 4.2e-95 sigH K Belongs to the sigma-70 factor family
AKKDOMIM_01701 6.6e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AKKDOMIM_01702 6.7e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AKKDOMIM_01703 2.9e-276 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AKKDOMIM_01704 1.9e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AKKDOMIM_01705 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AKKDOMIM_01706 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
AKKDOMIM_01707 2.7e-51
AKKDOMIM_01708 4.3e-266 pepC 3.4.22.40 E Peptidase C1-like family
AKKDOMIM_01709 3.3e-44
AKKDOMIM_01710 5.4e-183 S AAA domain
AKKDOMIM_01711 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AKKDOMIM_01712 1.4e-23
AKKDOMIM_01713 7.3e-161 czcD P cation diffusion facilitator family transporter
AKKDOMIM_01714 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
AKKDOMIM_01715 6e-132 S membrane transporter protein
AKKDOMIM_01716 1.9e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AKKDOMIM_01717 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
AKKDOMIM_01718 1.2e-49 S Protein of unknown function (DUF3021)
AKKDOMIM_01719 2.8e-14 L PFAM transposase, IS4 family protein
AKKDOMIM_01720 1.2e-44 K LytTr DNA-binding domain
AKKDOMIM_01721 1.2e-10
AKKDOMIM_01722 5.9e-13 K Acetyltransferase (GNAT) domain
AKKDOMIM_01723 1.9e-12 L Transposase
AKKDOMIM_01724 1.4e-16 L Transposase
AKKDOMIM_01725 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
AKKDOMIM_01726 5.2e-68 L haloacid dehalogenase-like hydrolase
AKKDOMIM_01727 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
AKKDOMIM_01728 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
AKKDOMIM_01729 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
AKKDOMIM_01730 1.8e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
AKKDOMIM_01731 2.9e-147 ulaA S PTS system sugar-specific permease component
AKKDOMIM_01732 2.4e-64 ulaA S PTS system sugar-specific permease component
AKKDOMIM_01733 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AKKDOMIM_01734 8.1e-175 ulaG S Beta-lactamase superfamily domain
AKKDOMIM_01735 2e-79 S helix_turn_helix, Deoxyribose operon repressor
AKKDOMIM_01736 3.3e-140 repB EP Plasmid replication protein
AKKDOMIM_01737 2.2e-22
AKKDOMIM_01738 3.6e-183 L Phage integrase family
AKKDOMIM_01739 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
AKKDOMIM_01740 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AKKDOMIM_01741 8.4e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AKKDOMIM_01742 7.2e-136 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AKKDOMIM_01743 4.6e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AKKDOMIM_01744 4.1e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AKKDOMIM_01745 1.4e-60 rplQ J Ribosomal protein L17
AKKDOMIM_01746 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKKDOMIM_01747 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AKKDOMIM_01748 3.6e-55 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AKKDOMIM_01749 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AKKDOMIM_01750 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AKKDOMIM_01751 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AKKDOMIM_01752 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AKKDOMIM_01753 2.6e-71 rplO J Binds to the 23S rRNA
AKKDOMIM_01754 2.3e-24 rpmD J Ribosomal protein L30
AKKDOMIM_01755 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AKKDOMIM_01756 1.1e-54 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AKKDOMIM_01757 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AKKDOMIM_01758 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AKKDOMIM_01759 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AKKDOMIM_01760 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AKKDOMIM_01761 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AKKDOMIM_01762 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AKKDOMIM_01763 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AKKDOMIM_01764 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
AKKDOMIM_01765 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AKKDOMIM_01766 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AKKDOMIM_01767 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AKKDOMIM_01768 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AKKDOMIM_01769 7.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AKKDOMIM_01770 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AKKDOMIM_01771 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
AKKDOMIM_01772 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AKKDOMIM_01773 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
AKKDOMIM_01774 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AKKDOMIM_01775 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AKKDOMIM_01776 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AKKDOMIM_01777 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
AKKDOMIM_01778 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKKDOMIM_01779 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AKKDOMIM_01780 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
AKKDOMIM_01781 1.3e-81 yebR 1.8.4.14 T GAF domain-containing protein
AKKDOMIM_01783 1.6e-08
AKKDOMIM_01784 1.6e-08
AKKDOMIM_01785 1.6e-08
AKKDOMIM_01786 1.4e-83 K FR47-like protein
AKKDOMIM_01787 3.1e-26 E Zn peptidase
AKKDOMIM_01788 1.1e-14 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_01789 2.5e-20
AKKDOMIM_01790 1.3e-19
AKKDOMIM_01791 2.1e-34 S Domain of unknown function (DUF4417)
AKKDOMIM_01792 5.4e-178 L COG3547 Transposase and inactivated derivatives
AKKDOMIM_01793 3.1e-227 L COG2963 Transposase and inactivated derivatives
AKKDOMIM_01794 1.7e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AKKDOMIM_01795 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AKKDOMIM_01796 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AKKDOMIM_01797 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AKKDOMIM_01798 1.5e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AKKDOMIM_01799 1.8e-62 yabR J S1 RNA binding domain
AKKDOMIM_01800 6.8e-60 divIC D Septum formation initiator
AKKDOMIM_01801 1.6e-33 yabO J S4 domain protein
AKKDOMIM_01802 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AKKDOMIM_01803 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AKKDOMIM_01804 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AKKDOMIM_01805 3.4e-129 S (CBS) domain
AKKDOMIM_01806 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AKKDOMIM_01807 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AKKDOMIM_01808 4.8e-250 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AKKDOMIM_01809 1.3e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AKKDOMIM_01810 2.5e-39 rpmE2 J Ribosomal protein L31
AKKDOMIM_01811 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
AKKDOMIM_01812 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
AKKDOMIM_01813 9.5e-297 ybeC E amino acid
AKKDOMIM_01814 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AKKDOMIM_01815 2.1e-42
AKKDOMIM_01816 1.4e-51
AKKDOMIM_01817 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
AKKDOMIM_01818 1.3e-141 yfeO P Voltage gated chloride channel
AKKDOMIM_01819 1e-95
AKKDOMIM_01820 7.8e-78 2.5.1.74 H UbiA prenyltransferase family
AKKDOMIM_01822 4.5e-185 3.2.1.18 GH33 M Rib/alpha-like repeat
AKKDOMIM_01823 8.7e-117 3.2.1.18 GH33 M Rib/alpha-like repeat
AKKDOMIM_01824 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
AKKDOMIM_01826 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AKKDOMIM_01827 2.4e-43 K Helix-turn-helix
AKKDOMIM_01828 3.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AKKDOMIM_01829 1.4e-226 pbuX F xanthine permease
AKKDOMIM_01830 2.5e-152 msmR K AraC-like ligand binding domain
AKKDOMIM_01831 4.4e-285 pipD E Dipeptidase
AKKDOMIM_01832 1.3e-47 adk 2.7.4.3 F AAA domain
AKKDOMIM_01833 2.1e-80 K acetyltransferase
AKKDOMIM_01834 1.4e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AKKDOMIM_01835 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AKKDOMIM_01836 1.8e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AKKDOMIM_01837 4.5e-68 S Domain of unknown function (DUF1934)
AKKDOMIM_01838 9.4e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
AKKDOMIM_01839 6.6e-44
AKKDOMIM_01840 1.6e-171 2.7.1.2 GK ROK family
AKKDOMIM_01841 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AKKDOMIM_01842 2e-295 S SLAP domain
AKKDOMIM_01843 5.3e-80
AKKDOMIM_01844 2e-160 S Uncharacterised protein family (UPF0236)
AKKDOMIM_01845 1.3e-172 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AKKDOMIM_01846 1.1e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
AKKDOMIM_01847 4.5e-39 veg S Biofilm formation stimulator VEG
AKKDOMIM_01848 3e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AKKDOMIM_01849 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AKKDOMIM_01850 1e-147 tatD L hydrolase, TatD family
AKKDOMIM_01851 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AKKDOMIM_01852 1e-307 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
AKKDOMIM_01853 1.5e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
AKKDOMIM_01854 2e-103 S TPM domain
AKKDOMIM_01855 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
AKKDOMIM_01856 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
AKKDOMIM_01857 1.2e-111 E Belongs to the SOS response-associated peptidase family
AKKDOMIM_01859 7.9e-112
AKKDOMIM_01860 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AKKDOMIM_01861 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
AKKDOMIM_01862 5.2e-256 pepC 3.4.22.40 E aminopeptidase
AKKDOMIM_01863 1.9e-175 oppF P Belongs to the ABC transporter superfamily
AKKDOMIM_01864 2.3e-198 oppD P Belongs to the ABC transporter superfamily
AKKDOMIM_01865 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKKDOMIM_01866 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
AKKDOMIM_01867 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AKKDOMIM_01868 3e-270 L Transposase DDE domain
AKKDOMIM_01869 1.6e-310 oppA E ABC transporter, substratebinding protein
AKKDOMIM_01870 7.1e-300 oppA E ABC transporter, substratebinding protein
AKKDOMIM_01871 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
AKKDOMIM_01872 4.6e-257 pepC 3.4.22.40 E aminopeptidase
AKKDOMIM_01874 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AKKDOMIM_01875 8.4e-265 S Fibronectin type III domain
AKKDOMIM_01876 1.3e-44 L COG3547 Transposase and inactivated derivatives
AKKDOMIM_01877 0.0 XK27_08315 M Sulfatase
AKKDOMIM_01878 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AKKDOMIM_01879 5.2e-201 brpA K Cell envelope-like function transcriptional attenuator common domain protein
AKKDOMIM_01880 1.4e-98 G Aldose 1-epimerase
AKKDOMIM_01881 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AKKDOMIM_01882 2.1e-116
AKKDOMIM_01883 2.1e-130
AKKDOMIM_01884 1.7e-160 S Oxidoreductase family, NAD-binding Rossmann fold
AKKDOMIM_01885 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AKKDOMIM_01886 1.9e-113 yjbQ P TrkA C-terminal domain protein
AKKDOMIM_01887 8.8e-177 yjbQ P TrkA C-terminal domain protein
AKKDOMIM_01888 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
AKKDOMIM_01889 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AKKDOMIM_01891 6.5e-105 S SLAP domain
AKKDOMIM_01892 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
AKKDOMIM_01893 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
AKKDOMIM_01894 1.1e-25
AKKDOMIM_01895 1.2e-77 K DNA-templated transcription, initiation
AKKDOMIM_01896 5.3e-41
AKKDOMIM_01898 3.6e-132 S SLAP domain
AKKDOMIM_01899 4.3e-40 S Protein of unknown function (DUF2922)
AKKDOMIM_01900 5.5e-30
AKKDOMIM_01902 5.9e-45
AKKDOMIM_01903 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
AKKDOMIM_01905 2.1e-45 S PFAM Archaeal ATPase
AKKDOMIM_01906 7.3e-74
AKKDOMIM_01907 0.0 kup P Transport of potassium into the cell
AKKDOMIM_01908 0.0 pepO 3.4.24.71 O Peptidase family M13
AKKDOMIM_01909 2.3e-210 yttB EGP Major facilitator Superfamily
AKKDOMIM_01910 1.5e-230 XK27_04775 S PAS domain
AKKDOMIM_01911 2.1e-103 S Iron-sulfur cluster assembly protein
AKKDOMIM_01912 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AKKDOMIM_01913 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AKKDOMIM_01914 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
AKKDOMIM_01915 0.0 asnB 6.3.5.4 E Asparagine synthase
AKKDOMIM_01916 1.6e-271 S Calcineurin-like phosphoesterase
AKKDOMIM_01917 3.9e-84
AKKDOMIM_01918 1.6e-105 tag 3.2.2.20 L glycosylase
AKKDOMIM_01919 8.4e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
AKKDOMIM_01920 2.9e-121 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
AKKDOMIM_01921 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AKKDOMIM_01922 1.2e-161 phnD P Phosphonate ABC transporter
AKKDOMIM_01924 8.8e-84 uspA T universal stress protein
AKKDOMIM_01925 9.8e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
AKKDOMIM_01926 1.7e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
AKKDOMIM_01927 3.6e-90 ntd 2.4.2.6 F Nucleoside
AKKDOMIM_01928 5.2e-08
AKKDOMIM_01929 5.4e-13
AKKDOMIM_01930 2.5e-214 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AKKDOMIM_01931 0.0 G Belongs to the glycosyl hydrolase 31 family
AKKDOMIM_01932 2.7e-146 I alpha/beta hydrolase fold
AKKDOMIM_01933 4.9e-129 yibF S overlaps another CDS with the same product name
AKKDOMIM_01934 2.2e-202 yibE S overlaps another CDS with the same product name
AKKDOMIM_01935 1.4e-112
AKKDOMIM_01936 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AKKDOMIM_01937 6.4e-224 S Cysteine-rich secretory protein family
AKKDOMIM_01938 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AKKDOMIM_01939 1.1e-257 glnPH2 P ABC transporter permease
AKKDOMIM_01940 2.8e-135
AKKDOMIM_01941 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
AKKDOMIM_01942 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AKKDOMIM_01943 5.6e-36
AKKDOMIM_01944 2e-139 L An automated process has identified a potential problem with this gene model
AKKDOMIM_01945 7.3e-126 S Alpha/beta hydrolase family
AKKDOMIM_01946 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
AKKDOMIM_01947 4.4e-140 ypuA S Protein of unknown function (DUF1002)
AKKDOMIM_01948 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AKKDOMIM_01949 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
AKKDOMIM_01950 1.2e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKKDOMIM_01951 9.3e-86
AKKDOMIM_01952 4e-20 L PFAM transposase, IS4 family protein
AKKDOMIM_01953 8.5e-133 cobB K SIR2 family
AKKDOMIM_01954 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
AKKDOMIM_01955 1.3e-124 terC P Integral membrane protein TerC family
AKKDOMIM_01956 5.8e-64 yeaO S Protein of unknown function, DUF488
AKKDOMIM_01957 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
AKKDOMIM_01958 1.3e-290 glnP P ABC transporter permease
AKKDOMIM_01959 3.4e-135 glnQ E ABC transporter, ATP-binding protein
AKKDOMIM_01960 2.5e-148 S Protein of unknown function (DUF805)
AKKDOMIM_01961 7.6e-160 L HNH nucleases
AKKDOMIM_01962 1.1e-118 yfbR S HD containing hydrolase-like enzyme
AKKDOMIM_01963 3.1e-131 G Glycosyl hydrolases family 8
AKKDOMIM_01964 5.6e-36 G Glycosyl hydrolases family 8
AKKDOMIM_01965 4.5e-189 ydaM M Glycosyl transferase
AKKDOMIM_01966 1.1e-07 S Uncharacterised protein family (UPF0236)
AKKDOMIM_01967 1.2e-17
AKKDOMIM_01968 1.4e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
AKKDOMIM_01969 2.9e-69 S Iron-sulphur cluster biosynthesis
AKKDOMIM_01970 5.8e-192 ybiR P Citrate transporter
AKKDOMIM_01971 9.7e-95 lemA S LemA family
AKKDOMIM_01972 1.7e-157 htpX O Belongs to the peptidase M48B family
AKKDOMIM_01973 7.9e-174 K helix_turn_helix, arabinose operon control protein
AKKDOMIM_01974 1.4e-248 cbiO1 S ABC transporter, ATP-binding protein
AKKDOMIM_01975 9.6e-78 P Cobalt transport protein
AKKDOMIM_01976 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
AKKDOMIM_01977 6.5e-91 G Peptidase_C39 like family
AKKDOMIM_01978 2.8e-162 M NlpC/P60 family
AKKDOMIM_01979 8.4e-25 G Peptidase_C39 like family
AKKDOMIM_01980 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AKKDOMIM_01981 1.6e-161 htrA 3.4.21.107 O serine protease
AKKDOMIM_01982 4.1e-147 vicX 3.1.26.11 S domain protein
AKKDOMIM_01983 3.4e-149 yycI S YycH protein
AKKDOMIM_01984 2.1e-257 yycH S YycH protein
AKKDOMIM_01985 2.2e-305 vicK 2.7.13.3 T Histidine kinase
AKKDOMIM_01986 4.8e-131 K response regulator
AKKDOMIM_01988 4.9e-34
AKKDOMIM_01990 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
AKKDOMIM_01991 1.5e-155 arbx M Glycosyl transferase family 8
AKKDOMIM_01993 1.5e-143 arbY M Glycosyl transferase family 8
AKKDOMIM_01994 8.7e-181 arbY M Glycosyl transferase family 8
AKKDOMIM_01995 1.9e-166 arbZ I Phosphate acyltransferases
AKKDOMIM_01996 4e-36 S Cytochrome B5
AKKDOMIM_02000 5.4e-53 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AKKDOMIM_02001 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AKKDOMIM_02002 1.7e-29 secG U Preprotein translocase
AKKDOMIM_02003 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
AKKDOMIM_02004 8.3e-177 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AKKDOMIM_02005 9.9e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
AKKDOMIM_02006 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
AKKDOMIM_02022 1.1e-103 M hydrolase, family 25
AKKDOMIM_02023 1.8e-38 S Bacteriophage holin of superfamily 6 (Holin_LLH)
AKKDOMIM_02031 3.8e-06 S Domain of unknown function (DUF2479)
AKKDOMIM_02033 0.0 S Phage minor structural protein
AKKDOMIM_02034 8.7e-110 S phage tail
AKKDOMIM_02035 0.0 xkdO D NLP P60 protein
AKKDOMIM_02036 1.6e-85 S Bacteriophage Gp15 protein
AKKDOMIM_02037 8.7e-35
AKKDOMIM_02038 4.6e-83 N domain, Protein
AKKDOMIM_02039 3e-51 S Minor capsid protein from bacteriophage
AKKDOMIM_02040 4e-31 S Minor capsid protein
AKKDOMIM_02041 1.6e-39 S Minor capsid protein
AKKDOMIM_02042 2.4e-44
AKKDOMIM_02043 4.6e-154 gpG
AKKDOMIM_02044 1e-36 S Phage minor structural protein GP20
AKKDOMIM_02046 5.7e-166 S Phage minor capsid protein 2
AKKDOMIM_02047 2.9e-216 S Phage portal protein, SPP1 Gp6-like
AKKDOMIM_02048 2.1e-214 S Terminase RNAseH like domain
AKKDOMIM_02049 8.3e-85 L transposase activity
AKKDOMIM_02050 5.4e-111 K Belongs to the N(4) N(6)-methyltransferase family
AKKDOMIM_02051 2.2e-30
AKKDOMIM_02053 2.2e-101 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
AKKDOMIM_02054 2.9e-42 S ASCH domain
AKKDOMIM_02055 2.9e-07
AKKDOMIM_02064 4.7e-55 dnaC L IstB-like ATP binding protein
AKKDOMIM_02065 1.7e-34 S Conserved phage C-terminus (Phg_2220_C)
AKKDOMIM_02066 1.2e-55 S Protein of unknown function (DUF1071)
AKKDOMIM_02070 2.9e-08
AKKDOMIM_02072 1.9e-108 K BRO family, N-terminal domain
AKKDOMIM_02074 9.8e-18 K Transcriptional
AKKDOMIM_02076 2.5e-11
AKKDOMIM_02078 4.5e-75 sip L Belongs to the 'phage' integrase family
AKKDOMIM_02095 1.6e-102 ltrA S Bacterial low temperature requirement A protein (LtrA)
AKKDOMIM_02096 7.4e-120 3.6.1.55 F NUDIX domain
AKKDOMIM_02097 1.5e-245 brnQ U Component of the transport system for branched-chain amino acids
AKKDOMIM_02098 0.0 L Plasmid pRiA4b ORF-3-like protein
AKKDOMIM_02099 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AKKDOMIM_02100 2.5e-08 S Protein of unknown function (DUF3021)
AKKDOMIM_02101 9e-34 K Bacterial regulatory helix-turn-helix protein, lysR family
AKKDOMIM_02102 9.5e-34 rmaI K Transcriptional regulator
AKKDOMIM_02103 5.4e-171 lmrB EGP Major facilitator Superfamily
AKKDOMIM_02104 7.8e-202 XK27_00915 C Luciferase-like monooxygenase
AKKDOMIM_02105 6.5e-87 K GNAT family
AKKDOMIM_02106 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
AKKDOMIM_02108 1.5e-36
AKKDOMIM_02109 2.6e-286 P ABC transporter
AKKDOMIM_02110 7.6e-242 V ABC-type multidrug transport system, ATPase and permease components
AKKDOMIM_02111 2.4e-251 yifK E Amino acid permease
AKKDOMIM_02112 3.1e-178 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AKKDOMIM_02113 1.2e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AKKDOMIM_02114 0.0 aha1 P E1-E2 ATPase
AKKDOMIM_02115 5.8e-177 F DNA/RNA non-specific endonuclease
AKKDOMIM_02116 1e-159 metQ2 P Belongs to the nlpA lipoprotein family
AKKDOMIM_02117 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AKKDOMIM_02118 2e-73 metI P ABC transporter permease
AKKDOMIM_02119 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AKKDOMIM_02120 1.9e-261 frdC 1.3.5.4 C FAD binding domain
AKKDOMIM_02121 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AKKDOMIM_02122 4.1e-253 pepC 3.4.22.40 E Peptidase C1-like family
AKKDOMIM_02123 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
AKKDOMIM_02124 4.7e-274 P Sodium:sulfate symporter transmembrane region
AKKDOMIM_02125 1.1e-152 ydjP I Alpha/beta hydrolase family
AKKDOMIM_02126 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AKKDOMIM_02127 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
AKKDOMIM_02128 3.8e-165 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
AKKDOMIM_02129 9.2e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
AKKDOMIM_02130 7.9e-71 yeaL S Protein of unknown function (DUF441)
AKKDOMIM_02131 1.8e-22
AKKDOMIM_02132 1.2e-144 cbiQ P cobalt transport
AKKDOMIM_02133 0.0 ykoD P ABC transporter, ATP-binding protein
AKKDOMIM_02134 1.5e-95 S UPF0397 protein
AKKDOMIM_02135 2.9e-66 S Domain of unknown function DUF1828
AKKDOMIM_02136 5.5e-09
AKKDOMIM_02137 3.8e-51
AKKDOMIM_02138 2.6e-177 citR K Putative sugar-binding domain
AKKDOMIM_02139 1.9e-250 yjjP S Putative threonine/serine exporter
AKKDOMIM_02141 1.4e-39
AKKDOMIM_02142 2.3e-25 M domain protein
AKKDOMIM_02143 1.1e-84 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AKKDOMIM_02144 1.2e-174 prmA J Ribosomal protein L11 methyltransferase
AKKDOMIM_02145 4.2e-36
AKKDOMIM_02146 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AKKDOMIM_02147 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AKKDOMIM_02148 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
AKKDOMIM_02149 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AKKDOMIM_02150 9.8e-222 patA 2.6.1.1 E Aminotransferase
AKKDOMIM_02152 1e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AKKDOMIM_02153 4.8e-34 S reductase
AKKDOMIM_02154 4.4e-39 S reductase
AKKDOMIM_02155 2.7e-32 S reductase
AKKDOMIM_02156 8.4e-148 yxeH S hydrolase
AKKDOMIM_02157 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AKKDOMIM_02158 1.1e-243 yfnA E Amino Acid
AKKDOMIM_02159 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
AKKDOMIM_02160 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AKKDOMIM_02161 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AKKDOMIM_02162 7.7e-293 I Acyltransferase
AKKDOMIM_02163 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AKKDOMIM_02164 1.9e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AKKDOMIM_02165 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
AKKDOMIM_02166 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AKKDOMIM_02167 1.6e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
AKKDOMIM_02168 1.5e-22 S Protein of unknown function (DUF2929)
AKKDOMIM_02169 0.0 dnaE 2.7.7.7 L DNA polymerase
AKKDOMIM_02170 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AKKDOMIM_02171 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AKKDOMIM_02172 1e-167 cvfB S S1 domain
AKKDOMIM_02173 2.9e-165 xerD D recombinase XerD
AKKDOMIM_02174 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AKKDOMIM_02175 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AKKDOMIM_02176 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AKKDOMIM_02177 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AKKDOMIM_02178 8.7e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AKKDOMIM_02179 2.7e-18 M Lysin motif
AKKDOMIM_02180 5e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AKKDOMIM_02181 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
AKKDOMIM_02182 1.9e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AKKDOMIM_02183 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AKKDOMIM_02184 8.7e-229 S Tetratricopeptide repeat protein
AKKDOMIM_02185 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AKKDOMIM_02186 2.5e-11 L Transposase
AKKDOMIM_02187 4.3e-136 S Alpha/beta hydrolase family
AKKDOMIM_02188 8.6e-82 yxaM EGP Major facilitator Superfamily
AKKDOMIM_02189 5.2e-69 yxaM EGP Major facilitator Superfamily
AKKDOMIM_02190 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
AKKDOMIM_02191 1e-79 S AAA domain
AKKDOMIM_02192 3.3e-61 3.6.1.55 F NUDIX domain
AKKDOMIM_02193 1.9e-138 2.4.2.3 F Phosphorylase superfamily
AKKDOMIM_02194 9e-144 2.4.2.3 F Phosphorylase superfamily
AKKDOMIM_02195 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
AKKDOMIM_02196 9.7e-65 yagE E amino acid
AKKDOMIM_02197 8.4e-128 yagE E Amino acid permease
AKKDOMIM_02198 4.3e-86 3.4.21.96 S SLAP domain
AKKDOMIM_02199 4.6e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AKKDOMIM_02200 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AKKDOMIM_02201 1.2e-107 hlyIII S protein, hemolysin III
AKKDOMIM_02202 2e-144 DegV S Uncharacterised protein, DegV family COG1307
AKKDOMIM_02203 7.1e-36 yozE S Belongs to the UPF0346 family
AKKDOMIM_02204 1.1e-66 yjcE P NhaP-type Na H and K H
AKKDOMIM_02205 1.5e-40 yjcE P Sodium proton antiporter
AKKDOMIM_02206 1.9e-94 yjcE P Sodium proton antiporter
AKKDOMIM_02207 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AKKDOMIM_02208 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AKKDOMIM_02209 5.8e-152 dprA LU DNA protecting protein DprA
AKKDOMIM_02210 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AKKDOMIM_02211 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AKKDOMIM_02212 6.5e-141 xerC D Phage integrase, N-terminal SAM-like domain
AKKDOMIM_02213 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AKKDOMIM_02214 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AKKDOMIM_02215 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
AKKDOMIM_02216 1.1e-86 C Aldo keto reductase
AKKDOMIM_02217 7.1e-63 M LysM domain protein
AKKDOMIM_02218 1.6e-15 L hmm pf00665
AKKDOMIM_02219 1.2e-28 L COG2963 Transposase and inactivated derivatives
AKKDOMIM_02220 5e-164 4.2.1.53 S Myosin-crossreactive antigen
AKKDOMIM_02221 1.2e-177 4.2.1.53 S Myosin-crossreactive antigen
AKKDOMIM_02222 2.3e-90 yxdD K Bacterial regulatory proteins, tetR family
AKKDOMIM_02223 9.5e-259 emrY EGP Major facilitator Superfamily
AKKDOMIM_02228 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
AKKDOMIM_02229 5.8e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AKKDOMIM_02230 1.6e-199 pbpX V Beta-lactamase
AKKDOMIM_02231 1.3e-230 nhaC C Na H antiporter NhaC
AKKDOMIM_02232 4.5e-50
AKKDOMIM_02233 1.2e-105 ybhL S Belongs to the BI1 family
AKKDOMIM_02234 1.5e-65 K transcriptional regulator
AKKDOMIM_02235 6.7e-18
AKKDOMIM_02236 2.7e-171 yegS 2.7.1.107 G Lipid kinase
AKKDOMIM_02237 4.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKKDOMIM_02238 1.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AKKDOMIM_02239 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AKKDOMIM_02240 5.8e-203 camS S sex pheromone
AKKDOMIM_02241 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AKKDOMIM_02242 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AKKDOMIM_02243 2.5e-86 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
AKKDOMIM_02245 4.8e-84 ydcK S Belongs to the SprT family
AKKDOMIM_02246 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
AKKDOMIM_02247 3e-257 epsU S Polysaccharide biosynthesis protein
AKKDOMIM_02248 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
AKKDOMIM_02249 0.0 pacL 3.6.3.8 P P-type ATPase
AKKDOMIM_02250 1.3e-202 tnpB L Putative transposase DNA-binding domain
AKKDOMIM_02251 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AKKDOMIM_02252 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AKKDOMIM_02253 2.9e-204 csaB M Glycosyl transferases group 1
AKKDOMIM_02254 1.2e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
AKKDOMIM_02255 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
AKKDOMIM_02256 6.6e-125 gntR1 K UTRA
AKKDOMIM_02257 2.5e-179
AKKDOMIM_02258 1.9e-300 oppA2 E ABC transporter, substratebinding protein
AKKDOMIM_02261 1.1e-240 npr 1.11.1.1 C NADH oxidase
AKKDOMIM_02262 7.7e-12
AKKDOMIM_02263 3.7e-22 3.6.4.12 S transposase or invertase
AKKDOMIM_02264 6.7e-228 slpX S SLAP domain
AKKDOMIM_02265 4.4e-144 K SIS domain
AKKDOMIM_02266 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
AKKDOMIM_02267 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
AKKDOMIM_02268 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
AKKDOMIM_02270 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
AKKDOMIM_02272 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AKKDOMIM_02273 2.5e-118 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
AKKDOMIM_02274 2.6e-89 G Histidine phosphatase superfamily (branch 1)
AKKDOMIM_02275 1.2e-105 G Phosphoglycerate mutase family
AKKDOMIM_02276 1.1e-158 D nuclear chromosome segregation
AKKDOMIM_02277 5.8e-78 M LysM domain protein
AKKDOMIM_02278 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKKDOMIM_02279 1.8e-125 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKKDOMIM_02280 6.2e-12
AKKDOMIM_02281 1.2e-171 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
AKKDOMIM_02282 2.3e-30
AKKDOMIM_02284 2.9e-69 S Iron-sulphur cluster biosynthesis
AKKDOMIM_02285 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
AKKDOMIM_02286 6.2e-59 psiE S Phosphate-starvation-inducible E
AKKDOMIM_02288 1.2e-42 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AKKDOMIM_02289 2.9e-85 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AKKDOMIM_02290 4.3e-228 amtB P ammonium transporter
AKKDOMIM_02291 1.4e-60
AKKDOMIM_02292 0.0 lhr L DEAD DEAH box helicase
AKKDOMIM_02293 3.5e-244 P P-loop Domain of unknown function (DUF2791)
AKKDOMIM_02294 0.0 S TerB-C domain
AKKDOMIM_02295 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
AKKDOMIM_02296 3.9e-298 V ABC transporter transmembrane region
AKKDOMIM_02297 2.3e-156 K Helix-turn-helix XRE-family like proteins
AKKDOMIM_02298 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
AKKDOMIM_02299 2.1e-32
AKKDOMIM_02300 1.4e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
AKKDOMIM_02301 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
AKKDOMIM_02302 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
AKKDOMIM_02303 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AKKDOMIM_02304 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
AKKDOMIM_02305 0.0 mtlR K Mga helix-turn-helix domain
AKKDOMIM_02306 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AKKDOMIM_02307 6.8e-184 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AKKDOMIM_02308 8e-282 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AKKDOMIM_02309 1.7e-241 cycA E Amino acid permease
AKKDOMIM_02310 1.3e-85 maa S transferase hexapeptide repeat
AKKDOMIM_02311 3.3e-158 K Transcriptional regulator
AKKDOMIM_02312 1.1e-62 manO S Domain of unknown function (DUF956)
AKKDOMIM_02313 1e-173 manN G system, mannose fructose sorbose family IID component
AKKDOMIM_02314 1.7e-129 manY G PTS system
AKKDOMIM_02315 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
AKKDOMIM_02317 1.1e-164 S Protein of unknown function (DUF2974)
AKKDOMIM_02318 6.8e-108 glnP P ABC transporter permease
AKKDOMIM_02319 9.7e-91 gluC P ABC transporter permease
AKKDOMIM_02320 3.4e-149 glnH ET ABC transporter substrate-binding protein
AKKDOMIM_02321 1.9e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
AKKDOMIM_02322 4.7e-114 udk 2.7.1.48 F Zeta toxin
AKKDOMIM_02323 2.3e-151 G MFS/sugar transport protein
AKKDOMIM_02324 4.7e-85 G MFS/sugar transport protein
AKKDOMIM_02325 8.4e-102 S ABC-type cobalt transport system, permease component
AKKDOMIM_02326 0.0 V ABC transporter transmembrane region
AKKDOMIM_02327 1.5e-308 XK27_09600 V ABC transporter, ATP-binding protein
AKKDOMIM_02328 1.4e-80 K Transcriptional regulator, MarR family
AKKDOMIM_02329 1.9e-147 glnH ET ABC transporter
AKKDOMIM_02330 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
AKKDOMIM_02331 8.6e-243 steT E amino acid
AKKDOMIM_02332 9.8e-239 steT E amino acid
AKKDOMIM_02333 6.1e-151
AKKDOMIM_02334 5.9e-174 S Aldo keto reductase
AKKDOMIM_02335 2.2e-311 ybiT S ABC transporter, ATP-binding protein
AKKDOMIM_02336 1.7e-209 pepA E M42 glutamyl aminopeptidase
AKKDOMIM_02337 1.9e-43
AKKDOMIM_02338 6.9e-136
AKKDOMIM_02339 1.1e-217 mdtG EGP Major facilitator Superfamily
AKKDOMIM_02340 9.2e-262 emrY EGP Major facilitator Superfamily
AKKDOMIM_02341 4.7e-91 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AKKDOMIM_02342 2.9e-238 pyrP F Permease
AKKDOMIM_02343 2.9e-287 K Putative DNA-binding domain
AKKDOMIM_02344 2e-29
AKKDOMIM_02345 7.8e-157 S reductase
AKKDOMIM_02346 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)