ORF_ID e_value Gene_name EC_number CAZy COGs Description
PGIHDHAF_00001 6.8e-52 L transposase, IS605 OrfB family
PGIHDHAF_00002 1.5e-39 L Transposase
PGIHDHAF_00003 2.8e-44 L Transposase IS200 like
PGIHDHAF_00004 2.9e-81 tlpA2 L Transposase IS200 like
PGIHDHAF_00007 4.6e-39 L Transposase
PGIHDHAF_00008 2.4e-121 L transposase, IS605 OrfB family
PGIHDHAF_00009 9.8e-39 L Transposase and inactivated derivatives
PGIHDHAF_00010 6.7e-153 L Transposase
PGIHDHAF_00011 1.4e-30 L Transposase
PGIHDHAF_00012 6.5e-170 L transposase, IS605 OrfB family
PGIHDHAF_00013 4.7e-41 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PGIHDHAF_00014 1.5e-69 dxs 2.2.1.7 HI 1-deoxy-D-xylulose-5-phosphate synthase
PGIHDHAF_00015 6.4e-137 L Transposase and inactivated derivatives, IS30 family
PGIHDHAF_00025 4.1e-131 tra L Transposase and inactivated derivatives, IS30 family
PGIHDHAF_00026 2.2e-190 L Transposase and inactivated derivatives, IS30 family
PGIHDHAF_00027 3.9e-134 L PFAM transposase, IS4 family protein
PGIHDHAF_00028 1.5e-24 L Helix-turn-helix domain
PGIHDHAF_00029 3.6e-85 L hmm pf00665
PGIHDHAF_00030 3.1e-289 L Transposase IS66 family
PGIHDHAF_00031 4.4e-23 XK27_01125 L PFAM IS66 Orf2 family protein
PGIHDHAF_00032 9.8e-77
PGIHDHAF_00033 1.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
PGIHDHAF_00034 2.2e-27
PGIHDHAF_00035 2.5e-29 M domain protein
PGIHDHAF_00036 2.6e-236 kgtP EGP Sugar (and other) transporter
PGIHDHAF_00037 1.6e-140 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
PGIHDHAF_00038 7.5e-153 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGIHDHAF_00039 2.8e-149 isdE P Periplasmic binding protein
PGIHDHAF_00040 3e-94 M Iron Transport-associated domain
PGIHDHAF_00041 4.8e-284 isdH M Iron Transport-associated domain
PGIHDHAF_00042 2.5e-52
PGIHDHAF_00043 1.5e-53 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PGIHDHAF_00044 1.5e-90 P Cadmium resistance transporter
PGIHDHAF_00048 2.2e-39 C Aldo keto reductase
PGIHDHAF_00049 5.3e-15 K Bacterial regulatory helix-turn-helix protein, lysR family
PGIHDHAF_00050 1.6e-44 K Bacterial regulatory helix-turn-helix protein, lysR family
PGIHDHAF_00051 1.7e-08 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGIHDHAF_00052 1.8e-104 S Alpha/beta hydrolase family
PGIHDHAF_00053 2e-120 pnb C nitroreductase
PGIHDHAF_00054 1.3e-85 M hydrolase, family 25
PGIHDHAF_00055 1.3e-21 S Bacteriophage holin of superfamily 6 (Holin_LLH)
PGIHDHAF_00060 1.6e-221 S peptidoglycan catabolic process
PGIHDHAF_00061 4.2e-64 S Phage tail protein
PGIHDHAF_00062 9.9e-165 S peptidoglycan catabolic process
PGIHDHAF_00063 9.9e-39 S Pfam:Phage_TAC_12
PGIHDHAF_00064 6.2e-84 S Phage major tail protein 2
PGIHDHAF_00065 1.2e-43
PGIHDHAF_00066 4.2e-42 S exonuclease activity
PGIHDHAF_00067 8.2e-48 S Phage gp6-like head-tail connector protein
PGIHDHAF_00068 1.1e-118
PGIHDHAF_00069 2.3e-65 S aminoacyl-tRNA ligase activity
PGIHDHAF_00071 1.7e-137 S Phage Mu protein F like protein
PGIHDHAF_00072 6.5e-209 S Phage portal protein, SPP1 Gp6-like
PGIHDHAF_00073 4.9e-188 S Phage terminase, large subunit
PGIHDHAF_00074 1.5e-09 L Terminase small subunit
PGIHDHAF_00075 1e-11
PGIHDHAF_00076 3.1e-09
PGIHDHAF_00078 1.7e-21
PGIHDHAF_00081 2.8e-52 S hydrolase activity, acting on ester bonds
PGIHDHAF_00083 3.6e-73 S Virulence-associated protein E
PGIHDHAF_00084 7.1e-138 L PFAM Integrase catalytic region
PGIHDHAF_00085 2.1e-85 cps2J S Polysaccharide biosynthesis protein
PGIHDHAF_00086 1.1e-24 S Acyltransferase family
PGIHDHAF_00087 5.7e-89 S Cupin superfamily (DUF985)
PGIHDHAF_00088 8.8e-122 K response regulator
PGIHDHAF_00089 1.2e-208 hpk31 2.7.13.3 T Histidine kinase
PGIHDHAF_00090 2.5e-202 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PGIHDHAF_00091 2.6e-139 azlC E AzlC protein
PGIHDHAF_00092 1.2e-60 azlD S branched-chain amino acid
PGIHDHAF_00093 2.4e-163 K AI-2E family transporter
PGIHDHAF_00094 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PGIHDHAF_00095 5.3e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PGIHDHAF_00096 2.9e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PGIHDHAF_00097 1.2e-254 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PGIHDHAF_00098 4.5e-167 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
PGIHDHAF_00099 1.4e-236 S response to antibiotic
PGIHDHAF_00100 2.5e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PGIHDHAF_00101 1.5e-36 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGIHDHAF_00102 1.6e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGIHDHAF_00103 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGIHDHAF_00104 5.7e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PGIHDHAF_00105 4.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PGIHDHAF_00106 6e-108 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PGIHDHAF_00107 1.2e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PGIHDHAF_00108 2.9e-240 purD 6.3.4.13 F Belongs to the GARS family
PGIHDHAF_00109 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PGIHDHAF_00110 7.9e-224 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PGIHDHAF_00111 7.3e-178
PGIHDHAF_00112 2.5e-46 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PGIHDHAF_00113 5e-53 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PGIHDHAF_00114 0.0 copA 3.6.3.54 P P-type ATPase
PGIHDHAF_00115 7.1e-29 EGP Major facilitator Superfamily
PGIHDHAF_00116 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
PGIHDHAF_00117 2.6e-180 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGIHDHAF_00118 9.5e-63 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
PGIHDHAF_00119 3.4e-69 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
PGIHDHAF_00120 3.6e-40 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
PGIHDHAF_00123 2.9e-120 arcC 2.7.2.2 E Amino acid kinase family
PGIHDHAF_00124 2.7e-174 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PGIHDHAF_00125 1.1e-123 C nitroreductase
PGIHDHAF_00126 1.3e-136 E GDSL-like Lipase/Acylhydrolase family
PGIHDHAF_00127 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
PGIHDHAF_00128 3.6e-196 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PGIHDHAF_00129 0.0 pepN 3.4.11.2 E aminopeptidase
PGIHDHAF_00130 3.9e-57 K Transcriptional regulator
PGIHDHAF_00131 3e-24 phaG GT1 I carboxylic ester hydrolase activity
PGIHDHAF_00132 2.1e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PGIHDHAF_00134 1.8e-153 metQ_4 P Belongs to the nlpA lipoprotein family
PGIHDHAF_00135 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PGIHDHAF_00136 0.0 helD 3.6.4.12 L DNA helicase
PGIHDHAF_00137 6.6e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PGIHDHAF_00138 6.2e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PGIHDHAF_00139 6.5e-187
PGIHDHAF_00140 4.4e-129 cobB K SIR2 family
PGIHDHAF_00141 5.3e-212 norA EGP Major facilitator Superfamily
PGIHDHAF_00142 9.5e-163 yunF F Protein of unknown function DUF72
PGIHDHAF_00143 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGIHDHAF_00144 1.8e-147 tatD L hydrolase, TatD family
PGIHDHAF_00145 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PGIHDHAF_00146 2.1e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PGIHDHAF_00147 2.7e-157 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PGIHDHAF_00148 3.5e-163 znuA P Belongs to the bacterial solute-binding protein 9 family
PGIHDHAF_00149 3.9e-93 fhuC P ABC transporter
PGIHDHAF_00150 3.2e-128 znuB U ABC 3 transport family
PGIHDHAF_00151 7.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PGIHDHAF_00152 2.8e-204 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PGIHDHAF_00153 6.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PGIHDHAF_00154 3e-32
PGIHDHAF_00155 4.8e-143 yxeH S hydrolase
PGIHDHAF_00156 1.5e-266 ywfO S HD domain protein
PGIHDHAF_00157 3.2e-74 ywiB S Domain of unknown function (DUF1934)
PGIHDHAF_00158 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PGIHDHAF_00159 4.4e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PGIHDHAF_00160 5.2e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGIHDHAF_00161 6e-41 rpmE2 J Ribosomal protein L31
PGIHDHAF_00162 5.8e-50 mdtG EGP Major facilitator Superfamily
PGIHDHAF_00163 1.4e-44 mdtG EGP Major facilitator Superfamily
PGIHDHAF_00164 1.4e-122 srtA 3.4.22.70 M sortase family
PGIHDHAF_00165 4.8e-47 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PGIHDHAF_00166 4.3e-87 lemA S LemA family
PGIHDHAF_00167 4.9e-157 htpX O Belongs to the peptidase M48B family
PGIHDHAF_00168 2.1e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PGIHDHAF_00169 2.7e-253 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PGIHDHAF_00170 8.5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PGIHDHAF_00171 3.6e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PGIHDHAF_00172 5e-57 L Toxic component of a toxin-antitoxin (TA) module
PGIHDHAF_00173 8.1e-114 S (CBS) domain
PGIHDHAF_00174 8.2e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PGIHDHAF_00175 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PGIHDHAF_00176 4.8e-39 yabO J S4 domain protein
PGIHDHAF_00177 1.5e-56 divIC D Septum formation initiator
PGIHDHAF_00178 3e-87 yabR J RNA binding
PGIHDHAF_00179 6.9e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PGIHDHAF_00180 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PGIHDHAF_00181 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PGIHDHAF_00182 7.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PGIHDHAF_00183 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGIHDHAF_00184 1.2e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PGIHDHAF_00204 7.1e-17 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PGIHDHAF_00205 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PGIHDHAF_00206 1.5e-113 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PGIHDHAF_00207 8.8e-203 coiA 3.6.4.12 S Competence protein
PGIHDHAF_00208 3.6e-114 yjbH Q Thioredoxin
PGIHDHAF_00209 6e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
PGIHDHAF_00210 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PGIHDHAF_00211 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PGIHDHAF_00212 4e-195 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PGIHDHAF_00213 1.3e-162 rrmA 2.1.1.187 H Methyltransferase
PGIHDHAF_00214 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PGIHDHAF_00215 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PGIHDHAF_00216 1.2e-07 S Protein of unknown function (DUF4044)
PGIHDHAF_00217 5.8e-58
PGIHDHAF_00218 5.6e-79 mraZ K Belongs to the MraZ family
PGIHDHAF_00219 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PGIHDHAF_00220 7e-09 ftsL D Cell division protein FtsL
PGIHDHAF_00221 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PGIHDHAF_00222 9.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PGIHDHAF_00223 1e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PGIHDHAF_00224 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PGIHDHAF_00225 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PGIHDHAF_00226 3.2e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PGIHDHAF_00227 9e-221 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PGIHDHAF_00228 2.5e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PGIHDHAF_00229 6.8e-41 yggT S YGGT family
PGIHDHAF_00230 1.3e-145 ylmH S S4 domain protein
PGIHDHAF_00231 1.4e-111 divIVA D DivIVA domain protein
PGIHDHAF_00233 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PGIHDHAF_00234 1.2e-32 cspB K Cold shock protein
PGIHDHAF_00235 2.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PGIHDHAF_00237 4.6e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PGIHDHAF_00238 3.4e-58 XK27_04120 S Putative amino acid metabolism
PGIHDHAF_00239 2.9e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PGIHDHAF_00240 2.3e-306 S amidohydrolase
PGIHDHAF_00241 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PGIHDHAF_00242 1.6e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PGIHDHAF_00243 7.1e-124 S Repeat protein
PGIHDHAF_00244 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PGIHDHAF_00245 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PGIHDHAF_00246 4.2e-74 spx4 1.20.4.1 P ArsC family
PGIHDHAF_00247 9e-189 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
PGIHDHAF_00248 2.2e-31 ykzG S Belongs to the UPF0356 family
PGIHDHAF_00249 1.2e-74
PGIHDHAF_00250 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PGIHDHAF_00251 2.4e-49 yktA S Belongs to the UPF0223 family
PGIHDHAF_00252 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PGIHDHAF_00253 0.0 typA T GTP-binding protein TypA
PGIHDHAF_00254 8.1e-216 ftsW D Belongs to the SEDS family
PGIHDHAF_00255 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PGIHDHAF_00256 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PGIHDHAF_00257 9.6e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PGIHDHAF_00258 1.5e-197 ylbL T Belongs to the peptidase S16 family
PGIHDHAF_00259 1.3e-90 comEA L Competence protein ComEA
PGIHDHAF_00260 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
PGIHDHAF_00261 0.0 comEC S Competence protein ComEC
PGIHDHAF_00262 1.8e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
PGIHDHAF_00263 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
PGIHDHAF_00264 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PGIHDHAF_00265 5.6e-36 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PGIHDHAF_00266 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGIHDHAF_00267 1.1e-164 S Tetratricopeptide repeat
PGIHDHAF_00268 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PGIHDHAF_00269 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PGIHDHAF_00270 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PGIHDHAF_00271 2.3e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
PGIHDHAF_00272 8.3e-53 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PGIHDHAF_00274 3.7e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PGIHDHAF_00275 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PGIHDHAF_00276 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PGIHDHAF_00277 4.1e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PGIHDHAF_00278 4.3e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PGIHDHAF_00279 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PGIHDHAF_00280 2.4e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PGIHDHAF_00281 2.9e-51 S Domain of unknown function (DUF4440)
PGIHDHAF_00282 3.3e-186 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGIHDHAF_00283 1.1e-152 tesE Q hydratase
PGIHDHAF_00284 2.9e-43 adhR K helix_turn_helix, mercury resistance
PGIHDHAF_00285 6.2e-99 ywrO S Flavodoxin-like fold
PGIHDHAF_00286 4.6e-45 S Protein conserved in bacteria
PGIHDHAF_00287 1.5e-55 1.14.99.57 S Antibiotic biosynthesis monooxygenase
PGIHDHAF_00288 2.1e-51 S Sugar efflux transporter for intercellular exchange
PGIHDHAF_00289 1.7e-16 xre K Helix-turn-helix domain
PGIHDHAF_00290 1.1e-198 gldA 1.1.1.6 C dehydrogenase
PGIHDHAF_00291 5.1e-119 IQ Enoyl-(Acyl carrier protein) reductase
PGIHDHAF_00292 9.9e-08 S Bacterial transferase hexapeptide (six repeats)
PGIHDHAF_00294 0.0 asnB 6.3.5.4 E Aluminium induced protein
PGIHDHAF_00297 1.4e-12 S CHY zinc finger
PGIHDHAF_00299 1.5e-17 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PGIHDHAF_00300 2.8e-12
PGIHDHAF_00301 3e-184 scrR3 K Transcriptional regulator, LacI family
PGIHDHAF_00302 1.3e-78 F Nucleoside 2-deoxyribosyltransferase
PGIHDHAF_00303 2.1e-90
PGIHDHAF_00305 1.3e-124 L Belongs to the 'phage' integrase family
PGIHDHAF_00306 2.7e-31
PGIHDHAF_00307 7e-22
PGIHDHAF_00309 2.4e-31 xkdA E Zn peptidase
PGIHDHAF_00310 2.9e-22 K sequence-specific DNA binding
PGIHDHAF_00311 7.9e-14 K sequence-specific DNA binding
PGIHDHAF_00316 3.3e-43 S Siphovirus Gp157
PGIHDHAF_00317 2.6e-141 ET Bacterial periplasmic substrate-binding proteins
PGIHDHAF_00318 2.2e-109 XK27_05795 P ABC transporter permease
PGIHDHAF_00319 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PGIHDHAF_00320 5.3e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PGIHDHAF_00321 1.1e-158 sufD O Uncharacterized protein family (UPF0051)
PGIHDHAF_00322 4.6e-236 F Permease
PGIHDHAF_00323 9.4e-200 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
PGIHDHAF_00325 1.5e-43 lytE M LysM domain protein
PGIHDHAF_00326 2.8e-85 ykhA 3.1.2.20 I Thioesterase superfamily
PGIHDHAF_00327 2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
PGIHDHAF_00328 4.2e-116 K Transcriptional regulator, TetR family
PGIHDHAF_00331 4e-22
PGIHDHAF_00332 3.5e-247 cycA E Amino acid permease
PGIHDHAF_00333 6.2e-84 perR P Belongs to the Fur family
PGIHDHAF_00334 2.6e-253 EGP Major facilitator Superfamily
PGIHDHAF_00335 1.2e-97 tag 3.2.2.20 L glycosylase
PGIHDHAF_00336 1.3e-51
PGIHDHAF_00337 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PGIHDHAF_00338 8.2e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PGIHDHAF_00339 6.4e-224 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PGIHDHAF_00340 7.8e-126 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
PGIHDHAF_00341 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PGIHDHAF_00342 2.6e-42
PGIHDHAF_00343 1e-298 ytgP S Polysaccharide biosynthesis protein
PGIHDHAF_00344 9.5e-62 3.2.1.23 S Domain of unknown function DUF302
PGIHDHAF_00345 1.1e-156 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PGIHDHAF_00346 2.9e-273 pepV 3.5.1.18 E dipeptidase PepV
PGIHDHAF_00347 5.1e-87 uspA T Belongs to the universal stress protein A family
PGIHDHAF_00348 7.1e-256 S Putative peptidoglycan binding domain
PGIHDHAF_00349 1.5e-155 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PGIHDHAF_00350 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
PGIHDHAF_00351 3.6e-111
PGIHDHAF_00352 9.9e-183 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
PGIHDHAF_00353 4e-119 S CAAX protease self-immunity
PGIHDHAF_00354 8.4e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PGIHDHAF_00355 1.5e-94 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PGIHDHAF_00356 8.9e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
PGIHDHAF_00357 5.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PGIHDHAF_00358 2.6e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
PGIHDHAF_00359 5.7e-203 folP 2.5.1.15 H dihydropteroate synthase
PGIHDHAF_00361 1.7e-36
PGIHDHAF_00363 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PGIHDHAF_00364 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PGIHDHAF_00365 9.8e-56 yheA S Belongs to the UPF0342 family
PGIHDHAF_00366 1.3e-179 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
PGIHDHAF_00367 4.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PGIHDHAF_00369 1.4e-77 hit FG histidine triad
PGIHDHAF_00370 2.3e-133 ecsA V ABC transporter, ATP-binding protein
PGIHDHAF_00371 7.7e-211 ecsB U ABC transporter
PGIHDHAF_00372 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PGIHDHAF_00373 3.3e-58 ytzB S Small secreted protein
PGIHDHAF_00374 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PGIHDHAF_00375 2e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGIHDHAF_00376 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PGIHDHAF_00377 1.8e-114 ybhL S Belongs to the BI1 family
PGIHDHAF_00378 1.1e-138 aroD S Serine hydrolase (FSH1)
PGIHDHAF_00379 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGIHDHAF_00380 1.8e-161 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PGIHDHAF_00381 3.5e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGIHDHAF_00382 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PGIHDHAF_00383 1e-251 dnaB L replication initiation and membrane attachment
PGIHDHAF_00384 2.5e-172 dnaI L Primosomal protein DnaI
PGIHDHAF_00385 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PGIHDHAF_00386 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PGIHDHAF_00387 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PGIHDHAF_00388 9.4e-19 yoaK S Protein of unknown function (DUF1275)
PGIHDHAF_00389 2e-25 yoaK S Protein of unknown function (DUF1275)
PGIHDHAF_00390 7.6e-97 yqeG S HAD phosphatase, family IIIA
PGIHDHAF_00391 7.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
PGIHDHAF_00392 2.6e-49 yhbY J RNA-binding protein
PGIHDHAF_00393 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PGIHDHAF_00394 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PGIHDHAF_00395 1.6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PGIHDHAF_00396 3.1e-141 yqeM Q Methyltransferase
PGIHDHAF_00397 4.5e-216 ylbM S Belongs to the UPF0348 family
PGIHDHAF_00398 1.2e-97 yceD S Uncharacterized ACR, COG1399
PGIHDHAF_00399 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PGIHDHAF_00400 5.6e-121 K response regulator
PGIHDHAF_00401 9e-281 arlS 2.7.13.3 T Histidine kinase
PGIHDHAF_00402 1.6e-233 V MatE
PGIHDHAF_00403 5.1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PGIHDHAF_00404 1e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGIHDHAF_00405 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PGIHDHAF_00406 1.5e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGIHDHAF_00407 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PGIHDHAF_00408 7.8e-60 yodB K Transcriptional regulator, HxlR family
PGIHDHAF_00409 5.1e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PGIHDHAF_00410 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGIHDHAF_00411 8.8e-116 udk 2.7.1.48 F Cytidine monophosphokinase
PGIHDHAF_00412 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PGIHDHAF_00413 0.0 S membrane
PGIHDHAF_00414 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PGIHDHAF_00415 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PGIHDHAF_00416 9.2e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PGIHDHAF_00417 1.1e-116 gluP 3.4.21.105 S Peptidase, S54 family
PGIHDHAF_00418 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
PGIHDHAF_00419 1.2e-180 glk 2.7.1.2 G Glucokinase
PGIHDHAF_00420 1.5e-71 yqhL P Rhodanese-like protein
PGIHDHAF_00421 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
PGIHDHAF_00422 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PGIHDHAF_00423 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
PGIHDHAF_00424 4.7e-13
PGIHDHAF_00425 2.4e-148
PGIHDHAF_00426 5.1e-176
PGIHDHAF_00427 1.5e-92 dut S Protein conserved in bacteria
PGIHDHAF_00429 2.8e-114 K Transcriptional regulator
PGIHDHAF_00430 8.9e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
PGIHDHAF_00431 9e-53 ysxB J Cysteine protease Prp
PGIHDHAF_00432 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PGIHDHAF_00433 3.1e-206 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PGIHDHAF_00434 4.1e-72 yqhY S Asp23 family, cell envelope-related function
PGIHDHAF_00435 4e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PGIHDHAF_00436 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PGIHDHAF_00437 3e-257 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGIHDHAF_00438 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGIHDHAF_00439 9.6e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PGIHDHAF_00440 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PGIHDHAF_00441 6.2e-76 argR K Regulates arginine biosynthesis genes
PGIHDHAF_00442 1.3e-307 recN L May be involved in recombinational repair of damaged DNA
PGIHDHAF_00443 1.6e-14
PGIHDHAF_00444 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PGIHDHAF_00445 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PGIHDHAF_00446 9.2e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PGIHDHAF_00447 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PGIHDHAF_00448 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PGIHDHAF_00449 4.5e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PGIHDHAF_00450 4.9e-131 stp 3.1.3.16 T phosphatase
PGIHDHAF_00451 0.0 KLT serine threonine protein kinase
PGIHDHAF_00452 8.2e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PGIHDHAF_00453 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PGIHDHAF_00454 1.2e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
PGIHDHAF_00455 7.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PGIHDHAF_00456 3.6e-58 asp S Asp23 family, cell envelope-related function
PGIHDHAF_00457 1.7e-304 yloV S DAK2 domain fusion protein YloV
PGIHDHAF_00458 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PGIHDHAF_00459 2.4e-163 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PGIHDHAF_00460 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGIHDHAF_00461 5.2e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PGIHDHAF_00462 0.0 smc D Required for chromosome condensation and partitioning
PGIHDHAF_00463 4.4e-198 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PGIHDHAF_00464 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PGIHDHAF_00465 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PGIHDHAF_00466 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
PGIHDHAF_00467 0.0 trxB2 1.8.1.9 C Thioredoxin domain
PGIHDHAF_00469 1.3e-84 K GNAT family
PGIHDHAF_00470 3.6e-123 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PGIHDHAF_00471 3.4e-160 ytbE 1.1.1.346 S Aldo keto reductase
PGIHDHAF_00472 1.7e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PGIHDHAF_00473 2.8e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PGIHDHAF_00475 1e-56
PGIHDHAF_00477 2.1e-07
PGIHDHAF_00478 1.8e-78 K Winged helix DNA-binding domain
PGIHDHAF_00479 0.0 lmrA V ABC transporter, ATP-binding protein
PGIHDHAF_00480 0.0 yfiC V ABC transporter
PGIHDHAF_00481 8.2e-193 ampC V Beta-lactamase
PGIHDHAF_00482 3.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGIHDHAF_00483 2.8e-48
PGIHDHAF_00484 2.9e-139 cobQ S CobB/CobQ-like glutamine amidotransferase domain
PGIHDHAF_00485 1.9e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
PGIHDHAF_00486 1.2e-108 tdk 2.7.1.21 F thymidine kinase
PGIHDHAF_00487 2.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PGIHDHAF_00488 7.1e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PGIHDHAF_00489 3.4e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PGIHDHAF_00490 4.6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PGIHDHAF_00491 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PGIHDHAF_00492 1.1e-185 yibE S overlaps another CDS with the same product name
PGIHDHAF_00493 3.3e-125 yibF S overlaps another CDS with the same product name
PGIHDHAF_00494 5.4e-218 pyrP F Permease
PGIHDHAF_00495 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
PGIHDHAF_00496 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGIHDHAF_00497 3.7e-53 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PGIHDHAF_00498 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGIHDHAF_00499 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PGIHDHAF_00500 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PGIHDHAF_00501 4.4e-253 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PGIHDHAF_00502 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PGIHDHAF_00503 2.8e-29 S Protein of unknown function (DUF1146)
PGIHDHAF_00504 5.5e-220 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
PGIHDHAF_00505 2.6e-183 mbl D Cell shape determining protein MreB Mrl
PGIHDHAF_00506 7.9e-32 S Protein of unknown function (DUF2969)
PGIHDHAF_00507 5.8e-222 rodA D Belongs to the SEDS family
PGIHDHAF_00509 1.5e-180 S Protein of unknown function (DUF2785)
PGIHDHAF_00510 1.7e-215 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PGIHDHAF_00511 1.4e-150 2.3.1.19 K Helix-turn-helix XRE-family like proteins
PGIHDHAF_00512 2.3e-81 usp6 T universal stress protein
PGIHDHAF_00514 8.4e-235 rarA L recombination factor protein RarA
PGIHDHAF_00515 4.5e-85 yueI S Protein of unknown function (DUF1694)
PGIHDHAF_00516 1.3e-75 4.4.1.5 E Glyoxalase
PGIHDHAF_00517 5.3e-133 S Membrane
PGIHDHAF_00518 2.3e-148 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGIHDHAF_00519 2.1e-25 S YjcQ protein
PGIHDHAF_00520 1.1e-211 L Belongs to the 'phage' integrase family
PGIHDHAF_00521 1.2e-29
PGIHDHAF_00522 1.2e-15 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
PGIHDHAF_00528 1.6e-22 K Cro/C1-type HTH DNA-binding domain
PGIHDHAF_00529 2.7e-16 K Helix-turn-helix XRE-family like proteins
PGIHDHAF_00530 7.2e-10 S Domain of unknown function (DUF771)
PGIHDHAF_00534 4.1e-20 S Bacteriophage Mu Gam like protein
PGIHDHAF_00535 5.6e-84 L AAA domain
PGIHDHAF_00536 5.7e-31
PGIHDHAF_00537 7.8e-82 S Bifunctional DNA primase/polymerase, N-terminal
PGIHDHAF_00538 3.5e-53 S Virulence-associated protein E
PGIHDHAF_00542 6.8e-20
PGIHDHAF_00544 8.1e-87 S Domain of unknown function (DUF4145)
PGIHDHAF_00545 1e-42
PGIHDHAF_00546 2.1e-75 L Phage terminase, small subunit
PGIHDHAF_00547 0.0 S Phage Terminase
PGIHDHAF_00549 7.9e-180 S Phage portal protein
PGIHDHAF_00550 5.6e-173 G Phage capsid family
PGIHDHAF_00551 6.2e-48
PGIHDHAF_00552 3.2e-14 S Phage head-tail joining protein
PGIHDHAF_00553 8.2e-33 S Bacteriophage HK97-gp10, putative tail-component
PGIHDHAF_00554 4.1e-17 S Protein of unknown function (DUF806)
PGIHDHAF_00555 1.2e-114 S Phage tail tube protein
PGIHDHAF_00556 3.3e-50 S Phage tail assembly chaperone proteins, TAC
PGIHDHAF_00557 0.0 M Phage tail tape measure protein TP901
PGIHDHAF_00558 4.1e-81 S Phage tail protein
PGIHDHAF_00559 1.6e-73 spr M Prophage endopeptidase tail
PGIHDHAF_00560 1.6e-74
PGIHDHAF_00562 4.3e-67 S Domain of unknown function (DUF2479)
PGIHDHAF_00567 1.4e-29 S Bacteriophage holin of superfamily 6 (Holin_LLH)
PGIHDHAF_00568 4.6e-205 3.5.1.104 M hydrolase, family 25
PGIHDHAF_00569 2.4e-306 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PGIHDHAF_00570 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
PGIHDHAF_00571 9.4e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGIHDHAF_00572 2.9e-211 EG GntP family permease
PGIHDHAF_00573 6.1e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PGIHDHAF_00574 1.2e-35 M LysM domain
PGIHDHAF_00575 2e-39
PGIHDHAF_00576 8.4e-24 S zinc-ribbon domain
PGIHDHAF_00579 1.6e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PGIHDHAF_00580 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PGIHDHAF_00581 4.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PGIHDHAF_00582 2.5e-115 radC L DNA repair protein
PGIHDHAF_00583 1.9e-181 mreB D cell shape determining protein MreB
PGIHDHAF_00584 3.7e-146 mreC M Involved in formation and maintenance of cell shape
PGIHDHAF_00585 4.3e-92 mreD M rod shape-determining protein MreD
PGIHDHAF_00586 1.4e-108 glnP P ABC transporter permease
PGIHDHAF_00587 2.2e-114 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PGIHDHAF_00588 2.4e-161 aatB ET ABC transporter substrate-binding protein
PGIHDHAF_00589 3.6e-230 ymfF S Peptidase M16 inactive domain protein
PGIHDHAF_00590 3.2e-250 ymfH S Peptidase M16
PGIHDHAF_00591 1.8e-96 ymfM S Helix-turn-helix domain
PGIHDHAF_00592 1.1e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGIHDHAF_00593 6e-230 cinA 3.5.1.42 S Belongs to the CinA family
PGIHDHAF_00594 2.2e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PGIHDHAF_00595 1e-202 rny S Endoribonuclease that initiates mRNA decay
PGIHDHAF_00596 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PGIHDHAF_00597 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PGIHDHAF_00598 1.1e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PGIHDHAF_00599 1.1e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PGIHDHAF_00600 7.5e-177 2.4.2.29 F queuine tRNA-ribosyltransferase activity
PGIHDHAF_00601 5.5e-42 yajC U Preprotein translocase
PGIHDHAF_00602 6.8e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PGIHDHAF_00603 4.2e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PGIHDHAF_00604 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGIHDHAF_00605 1.2e-42 yrzL S Belongs to the UPF0297 family
PGIHDHAF_00606 4.8e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PGIHDHAF_00607 5.7e-33 yrzB S Belongs to the UPF0473 family
PGIHDHAF_00608 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGIHDHAF_00609 3e-90 cvpA S Colicin V production protein
PGIHDHAF_00610 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PGIHDHAF_00611 1e-53 trxA O Belongs to the thioredoxin family
PGIHDHAF_00612 1.2e-225 clcA_2 P Chloride transporter, ClC family
PGIHDHAF_00613 1.6e-94 yslB S Protein of unknown function (DUF2507)
PGIHDHAF_00614 1.2e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PGIHDHAF_00615 3.6e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PGIHDHAF_00616 1.4e-95 S Phosphoesterase
PGIHDHAF_00617 4.9e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
PGIHDHAF_00618 4e-156 ykuT M mechanosensitive ion channel
PGIHDHAF_00619 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PGIHDHAF_00620 4.9e-70
PGIHDHAF_00621 2e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PGIHDHAF_00622 2.2e-185 ccpA K catabolite control protein A
PGIHDHAF_00623 3.6e-85
PGIHDHAF_00624 3.7e-134 yebC K Transcriptional regulatory protein
PGIHDHAF_00625 9.2e-83 mltD CBM50 M PFAM NLP P60 protein
PGIHDHAF_00626 4.6e-39 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
PGIHDHAF_00627 2.4e-108 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
PGIHDHAF_00628 2.7e-177 comGA NU Type II IV secretion system protein
PGIHDHAF_00629 3.5e-159 comGB NU type II secretion system
PGIHDHAF_00630 1.1e-47 comGC U competence protein ComGC
PGIHDHAF_00631 2.9e-15 NU general secretion pathway protein
PGIHDHAF_00633 3.8e-14
PGIHDHAF_00635 5.1e-159 ytxK 2.1.1.72 L N-6 DNA Methylase
PGIHDHAF_00636 9.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PGIHDHAF_00637 5.3e-110 S Calcineurin-like phosphoesterase
PGIHDHAF_00638 1.2e-97 yutD S Protein of unknown function (DUF1027)
PGIHDHAF_00639 1.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PGIHDHAF_00640 1.3e-24 S Protein of unknown function (DUF1461)
PGIHDHAF_00641 1e-103 dedA S SNARE-like domain protein
PGIHDHAF_00642 4.9e-295 xylB 2.7.1.12, 2.7.1.17 G Xylulose kinase
PGIHDHAF_00643 1.9e-269 xylA 5.3.1.5 G Belongs to the xylose isomerase family
PGIHDHAF_00644 9.5e-253 xylT EGP Major facilitator Superfamily
PGIHDHAF_00645 2.7e-216 xylR GK ROK family
PGIHDHAF_00646 5.9e-152 glcU U sugar transport
PGIHDHAF_00647 7.4e-251 yclK 2.7.13.3 T Histidine kinase
PGIHDHAF_00648 9.7e-132 K response regulator
PGIHDHAF_00650 2.3e-56 S Domain of unknown function (DUF956)
PGIHDHAF_00651 7.4e-169 manN G system, mannose fructose sorbose family IID component
PGIHDHAF_00652 2.7e-122 manY G PTS system
PGIHDHAF_00653 5.3e-181 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PGIHDHAF_00654 2.3e-181 yfeX P Peroxidase
PGIHDHAF_00655 6.5e-90 racA K Domain of unknown function (DUF1836)
PGIHDHAF_00656 9.5e-147 yitS S EDD domain protein, DegV family
PGIHDHAF_00657 1.3e-131 manA 5.3.1.8 G mannose-6-phosphate isomerase
PGIHDHAF_00658 4.7e-168 K LysR substrate binding domain
PGIHDHAF_00659 4.6e-159 MA20_14895 S Conserved hypothetical protein 698
PGIHDHAF_00660 2.4e-75 lytE M Lysin motif
PGIHDHAF_00661 2.6e-149 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
PGIHDHAF_00662 5.4e-211 oatA I Acyltransferase
PGIHDHAF_00663 3.3e-52
PGIHDHAF_00664 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PGIHDHAF_00665 1.1e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PGIHDHAF_00666 7.7e-115 ybbR S YbbR-like protein
PGIHDHAF_00667 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PGIHDHAF_00668 5.7e-166 murB 1.3.1.98 M Cell wall formation
PGIHDHAF_00669 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
PGIHDHAF_00670 3.3e-89 K Acetyltransferase (GNAT) domain
PGIHDHAF_00671 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PGIHDHAF_00672 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PGIHDHAF_00673 2.8e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PGIHDHAF_00674 1.1e-109 yxjI
PGIHDHAF_00675 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PGIHDHAF_00676 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PGIHDHAF_00677 4.5e-33 secG U Preprotein translocase
PGIHDHAF_00678 8.4e-290 clcA P chloride
PGIHDHAF_00679 1.5e-253 yifK E Amino acid permease
PGIHDHAF_00680 2.3e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PGIHDHAF_00681 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PGIHDHAF_00682 7.3e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PGIHDHAF_00683 1e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PGIHDHAF_00684 1e-15
PGIHDHAF_00685 8.3e-24 L Plasmid pRiA4b ORF-3-like protein
PGIHDHAF_00686 1.1e-78 tspO T TspO/MBR family
PGIHDHAF_00687 3.2e-13
PGIHDHAF_00688 1.4e-234 L Transposase
PGIHDHAF_00692 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PGIHDHAF_00693 2.5e-118 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PGIHDHAF_00694 1.9e-167 whiA K May be required for sporulation
PGIHDHAF_00695 1.7e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PGIHDHAF_00696 2.3e-159 rapZ S Displays ATPase and GTPase activities
PGIHDHAF_00697 2.2e-204
PGIHDHAF_00698 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PGIHDHAF_00699 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PGIHDHAF_00701 5.2e-113 yfbR S HD containing hydrolase-like enzyme
PGIHDHAF_00702 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PGIHDHAF_00703 2.8e-137 cof S haloacid dehalogenase-like hydrolase
PGIHDHAF_00704 1.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PGIHDHAF_00705 3.8e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PGIHDHAF_00706 1.2e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PGIHDHAF_00707 7.8e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PGIHDHAF_00708 1.7e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PGIHDHAF_00709 1.5e-76 yphH S Cupin domain
PGIHDHAF_00710 5.8e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PGIHDHAF_00711 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
PGIHDHAF_00712 7.5e-146 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PGIHDHAF_00713 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PGIHDHAF_00714 5.3e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PGIHDHAF_00715 4.7e-162 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PGIHDHAF_00716 9.2e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PGIHDHAF_00717 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PGIHDHAF_00718 4.1e-53 KT PspC domain protein
PGIHDHAF_00719 1.3e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PGIHDHAF_00720 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PGIHDHAF_00721 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PGIHDHAF_00722 1.2e-128 comFC S Competence protein
PGIHDHAF_00723 6.3e-254 comFA L Helicase C-terminal domain protein
PGIHDHAF_00724 1.1e-113 yvyE 3.4.13.9 S YigZ family
PGIHDHAF_00725 6.4e-38
PGIHDHAF_00726 0.0 ydaO E amino acid
PGIHDHAF_00727 1.4e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PGIHDHAF_00728 4.3e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PGIHDHAF_00729 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PGIHDHAF_00730 0.0 uup S ABC transporter, ATP-binding protein
PGIHDHAF_00731 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PGIHDHAF_00732 3.7e-91 bioY S BioY family
PGIHDHAF_00733 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PGIHDHAF_00734 1e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PGIHDHAF_00735 1.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PGIHDHAF_00736 7.1e-264 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PGIHDHAF_00737 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PGIHDHAF_00738 1.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PGIHDHAF_00739 6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PGIHDHAF_00740 7.8e-129 IQ reductase
PGIHDHAF_00741 1.1e-172 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PGIHDHAF_00742 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGIHDHAF_00743 1.8e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGIHDHAF_00744 2.3e-75 marR K Transcriptional regulator, MarR family
PGIHDHAF_00745 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PGIHDHAF_00747 1.2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PGIHDHAF_00748 1.3e-110 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PGIHDHAF_00749 2.2e-131 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PGIHDHAF_00750 7.6e-216 arcT 2.6.1.1 E Aminotransferase
PGIHDHAF_00751 2.7e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
PGIHDHAF_00752 1.2e-258 E Arginine ornithine antiporter
PGIHDHAF_00753 8.2e-240 arcA 3.5.3.6 E Arginine
PGIHDHAF_00754 1.4e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
PGIHDHAF_00755 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PGIHDHAF_00756 7.4e-147 KT YcbB domain
PGIHDHAF_00757 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PGIHDHAF_00758 6.7e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PGIHDHAF_00759 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PGIHDHAF_00760 4.8e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PGIHDHAF_00761 3.3e-146 fat 3.1.2.21 I Acyl-ACP thioesterase
PGIHDHAF_00762 1.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PGIHDHAF_00763 1.5e-55 yabA L Involved in initiation control of chromosome replication
PGIHDHAF_00764 1.4e-192 holB 2.7.7.7 L DNA polymerase III
PGIHDHAF_00765 4e-53 yaaQ S Cyclic-di-AMP receptor
PGIHDHAF_00766 6e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PGIHDHAF_00767 2.4e-21 S Protein of unknown function (DUF2508)
PGIHDHAF_00768 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PGIHDHAF_00769 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PGIHDHAF_00770 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGIHDHAF_00772 6.3e-80 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PGIHDHAF_00773 2e-35 nrdH O Glutaredoxin
PGIHDHAF_00774 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGIHDHAF_00775 8.6e-195 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGIHDHAF_00776 4.1e-248 brnQ U Component of the transport system for branched-chain amino acids
PGIHDHAF_00777 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PGIHDHAF_00778 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PGIHDHAF_00779 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PGIHDHAF_00780 4.1e-176 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PGIHDHAF_00781 1.1e-272 cydA 1.10.3.14 C ubiquinol oxidase
PGIHDHAF_00782 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PGIHDHAF_00783 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PGIHDHAF_00784 4.6e-244 steT E amino acid
PGIHDHAF_00785 7.4e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PGIHDHAF_00786 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PGIHDHAF_00787 4.5e-97 nusG K Participates in transcription elongation, termination and antitermination
PGIHDHAF_00788 6.9e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PGIHDHAF_00789 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PGIHDHAF_00790 1.1e-104 sigH K Belongs to the sigma-70 factor family
PGIHDHAF_00791 5.2e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGIHDHAF_00792 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PGIHDHAF_00793 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PGIHDHAF_00794 7.8e-100 ywlG S Belongs to the UPF0340 family
PGIHDHAF_00795 6.2e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PGIHDHAF_00796 3.2e-206 yacL S domain protein
PGIHDHAF_00797 5.6e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PGIHDHAF_00798 1.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PGIHDHAF_00799 4.2e-55 HA62_12640 S GCN5-related N-acetyl-transferase
PGIHDHAF_00800 6.7e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PGIHDHAF_00801 1.1e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
PGIHDHAF_00802 8.9e-264 pepC 3.4.22.40 E Peptidase C1-like family
PGIHDHAF_00803 1.3e-167 I alpha/beta hydrolase fold
PGIHDHAF_00804 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PGIHDHAF_00805 2.3e-168 mleP2 S Sodium Bile acid symporter family
PGIHDHAF_00806 1.3e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
PGIHDHAF_00807 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PGIHDHAF_00809 8.1e-84 ydcK S Belongs to the SprT family
PGIHDHAF_00810 0.0 yhgF K Tex-like protein N-terminal domain protein
PGIHDHAF_00811 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PGIHDHAF_00812 5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGIHDHAF_00813 2.8e-10 gntR1 K UbiC transcription regulator-associated domain protein
PGIHDHAF_00814 3.6e-100 gntR1 K UbiC transcription regulator-associated domain protein
PGIHDHAF_00815 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PGIHDHAF_00816 9.6e-115
PGIHDHAF_00819 5.1e-164 yjjH S Calcineurin-like phosphoesterase
PGIHDHAF_00820 6.5e-255 dtpT U amino acid peptide transporter
PGIHDHAF_00821 2.8e-169 D nuclear chromosome segregation
PGIHDHAF_00822 2.5e-75 L PFAM transposase, IS4 family protein
PGIHDHAF_00823 6.8e-20 L PFAM transposase, IS4 family protein
PGIHDHAF_00824 1.8e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
PGIHDHAF_00825 1.6e-154 tesE Q hydratase
PGIHDHAF_00826 1.7e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PGIHDHAF_00827 2.9e-62 K helix_turn_helix multiple antibiotic resistance protein
PGIHDHAF_00828 7.4e-99 M domain protein
PGIHDHAF_00829 8e-76 L Bacterial dnaA protein
PGIHDHAF_00830 5.1e-20 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGIHDHAF_00832 2.1e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PGIHDHAF_00833 4.7e-10 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PGIHDHAF_00834 1.9e-105 E Amino acid permease
PGIHDHAF_00835 1.1e-08 E Amino acid permease
PGIHDHAF_00836 4.7e-32 higA K Helix-turn-helix XRE-family like proteins
PGIHDHAF_00837 9.5e-30 S Sugar efflux transporter for intercellular exchange
PGIHDHAF_00838 2.5e-104 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
PGIHDHAF_00839 6.5e-38 tdh 1.1.1.14 C Zinc-binding dehydrogenase
PGIHDHAF_00840 3.5e-260 guaD 3.5.4.3 F Amidohydrolase family
PGIHDHAF_00841 4.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PGIHDHAF_00843 3.5e-57 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
PGIHDHAF_00844 6.2e-112 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PGIHDHAF_00845 4.7e-49 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
PGIHDHAF_00846 3.2e-89 rmeB K transcriptional regulator, MerR family
PGIHDHAF_00847 1.6e-132 ybbM S Uncharacterised protein family (UPF0014)
PGIHDHAF_00848 8.4e-111 ybbL S ABC transporter, ATP-binding protein
PGIHDHAF_00849 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PGIHDHAF_00851 1.3e-56 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
PGIHDHAF_00852 0.0 L Type III restriction enzyme, res subunit
PGIHDHAF_00854 2.4e-101 K DNA-templated transcription, initiation
PGIHDHAF_00855 1.4e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PGIHDHAF_00856 2e-29 arsD S Arsenical resistance operon trans-acting repressor ArsD
PGIHDHAF_00857 6e-233 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PGIHDHAF_00858 1.8e-56 arsR K Helix-turn-helix domain
PGIHDHAF_00859 3.8e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGIHDHAF_00860 2.2e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGIHDHAF_00861 4.9e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PGIHDHAF_00862 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
PGIHDHAF_00863 2.4e-311 ubiB S ABC1 family
PGIHDHAF_00864 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
PGIHDHAF_00865 2e-169 GK ROK family
PGIHDHAF_00866 3.9e-41
PGIHDHAF_00867 1.2e-79 copY K Copper transport repressor CopY TcrY
PGIHDHAF_00869 1.5e-46 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
PGIHDHAF_00870 1.2e-11 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PGIHDHAF_00871 4.3e-50 mutR K Transcriptional activator, Rgg GadR MutR family
PGIHDHAF_00872 9.1e-107 mutR K Transcriptional activator, Rgg GadR MutR family
PGIHDHAF_00873 1.2e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
PGIHDHAF_00874 3.2e-229 gntT EG Gluconate
PGIHDHAF_00875 2.2e-182 K Transcriptional regulator, LacI family
PGIHDHAF_00876 2.5e-61 yneR
PGIHDHAF_00877 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PGIHDHAF_00878 2.2e-96 V VanZ like family
PGIHDHAF_00879 1.7e-287 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PGIHDHAF_00880 1.2e-48 ywnB S NAD(P)H-binding
PGIHDHAF_00881 1.2e-65 yjcE P Sodium proton antiporter
PGIHDHAF_00882 5.9e-76
PGIHDHAF_00883 2.8e-81
PGIHDHAF_00884 3.6e-94
PGIHDHAF_00885 3.7e-128 narI 1.7.5.1 C Nitrate reductase
PGIHDHAF_00886 3.1e-102 narJ C Nitrate reductase delta subunit
PGIHDHAF_00887 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
PGIHDHAF_00888 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PGIHDHAF_00889 4.1e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
PGIHDHAF_00890 1.9e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PGIHDHAF_00891 1.5e-230 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
PGIHDHAF_00892 7.2e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PGIHDHAF_00893 3.7e-99 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PGIHDHAF_00894 4.2e-40
PGIHDHAF_00895 1.4e-77 nreA T GAF domain
PGIHDHAF_00896 2.3e-182 comP 2.7.13.3 F Sensor histidine kinase
PGIHDHAF_00897 3e-116 nreC K PFAM regulatory protein LuxR
PGIHDHAF_00898 1.2e-39
PGIHDHAF_00899 3e-184
PGIHDHAF_00900 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
PGIHDHAF_00902 4.6e-134 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PGIHDHAF_00903 4.5e-163 hipB K Helix-turn-helix
PGIHDHAF_00904 1.5e-58 yitW S Iron-sulfur cluster assembly protein
PGIHDHAF_00905 3.6e-216 narK P Major Facilitator Superfamily
PGIHDHAF_00906 3.5e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PGIHDHAF_00907 1.1e-34 moaD 2.8.1.12 H ThiS family
PGIHDHAF_00908 2.2e-72 moaE 2.8.1.12 H MoaE protein
PGIHDHAF_00909 7.2e-68 S Flavodoxin
PGIHDHAF_00910 7.3e-170 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGIHDHAF_00911 1.7e-142 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
PGIHDHAF_00912 2.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
PGIHDHAF_00913 3e-53 yitW S Iron-sulfur cluster assembly protein
PGIHDHAF_00914 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
PGIHDHAF_00915 2.8e-257 XK27_04775 S PAS domain
PGIHDHAF_00916 2.4e-142 EG EamA-like transporter family
PGIHDHAF_00917 1.5e-176 fecB P Periplasmic binding protein
PGIHDHAF_00918 4.2e-272 sufB O assembly protein SufB
PGIHDHAF_00919 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
PGIHDHAF_00920 1.5e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PGIHDHAF_00921 1.9e-242 sufD O FeS assembly protein SufD
PGIHDHAF_00922 9.4e-144 sufC O FeS assembly ATPase SufC
PGIHDHAF_00923 3.9e-33 feoA P FeoA domain
PGIHDHAF_00924 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PGIHDHAF_00925 6.7e-23 S Virus attachment protein p12 family
PGIHDHAF_00926 2.7e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PGIHDHAF_00927 2.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PGIHDHAF_00928 5.7e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGIHDHAF_00929 7.1e-217 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
PGIHDHAF_00930 8.7e-90 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PGIHDHAF_00931 1.3e-196 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PGIHDHAF_00932 4.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PGIHDHAF_00933 5e-104
PGIHDHAF_00934 7.4e-214 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PGIHDHAF_00935 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
PGIHDHAF_00936 2.1e-211 ydiN G Major Facilitator Superfamily
PGIHDHAF_00938 2.5e-243 dtpT U amino acid peptide transporter
PGIHDHAF_00941 1.7e-153 S Sucrose-6F-phosphate phosphohydrolase
PGIHDHAF_00942 1.2e-157 1.6.5.2 GM NAD(P)H-binding
PGIHDHAF_00943 1.6e-157 S Alpha beta hydrolase
PGIHDHAF_00944 2.7e-237 lmrB EGP Major facilitator Superfamily
PGIHDHAF_00946 0.0 S Bacterial membrane protein YfhO
PGIHDHAF_00947 0.0 kup P Transport of potassium into the cell
PGIHDHAF_00949 3.9e-284 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PGIHDHAF_00950 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PGIHDHAF_00951 0.0 yjbQ P TrkA C-terminal domain protein
PGIHDHAF_00952 1.4e-275 pipD E Dipeptidase
PGIHDHAF_00953 1.4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
PGIHDHAF_00954 8.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGIHDHAF_00955 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGIHDHAF_00956 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
PGIHDHAF_00957 2.8e-120 EGP Major facilitator Superfamily
PGIHDHAF_00958 9.2e-22 EGP Major facilitator Superfamily
PGIHDHAF_00959 1.5e-79 mdtG EGP Major facilitator Superfamily
PGIHDHAF_00960 1.7e-106 mdtG EGP Major facilitator Superfamily
PGIHDHAF_00961 2e-250 yhdP S Transporter associated domain
PGIHDHAF_00962 4.9e-216 naiP EGP Major facilitator Superfamily
PGIHDHAF_00963 4.1e-16 K LysR substrate binding domain protein
PGIHDHAF_00964 1e-43 K Transcriptional regulator
PGIHDHAF_00965 3.4e-216 E GDSL-like Lipase/Acylhydrolase family
PGIHDHAF_00966 7.9e-196 lplA 6.3.1.20 H Lipoate-protein ligase
PGIHDHAF_00967 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
PGIHDHAF_00968 1.5e-204 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGIHDHAF_00969 1.3e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PGIHDHAF_00970 4.8e-183 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PGIHDHAF_00971 1.1e-53 yphJ 4.1.1.44 S decarboxylase
PGIHDHAF_00972 2.8e-54 azlD E Branched-chain amino acid transport
PGIHDHAF_00973 4.6e-118 azlC E azaleucine resistance protein AzlC
PGIHDHAF_00974 6.1e-285 thrC 4.2.3.1 E Threonine synthase
PGIHDHAF_00975 3.5e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PGIHDHAF_00976 8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PGIHDHAF_00977 3.5e-99 K Acetyltransferase (GNAT) domain
PGIHDHAF_00978 7.6e-112 ylbE GM NAD(P)H-binding
PGIHDHAF_00979 1.6e-117 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PGIHDHAF_00980 7.7e-132 S Belongs to the UPF0246 family
PGIHDHAF_00981 1.3e-97
PGIHDHAF_00982 3.2e-161 degV S EDD domain protein, DegV family
PGIHDHAF_00983 0.0 FbpA K Fibronectin-binding protein
PGIHDHAF_00984 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
PGIHDHAF_00985 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PGIHDHAF_00986 6.9e-206 carA 6.3.5.5 F Belongs to the CarA family
PGIHDHAF_00987 1.2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PGIHDHAF_00988 3e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PGIHDHAF_00989 1.7e-70 esbA S Family of unknown function (DUF5322)
PGIHDHAF_00990 3.1e-71 rnhA 3.1.26.4 L Ribonuclease HI
PGIHDHAF_00991 8.7e-110 XK27_02070 S Nitroreductase family
PGIHDHAF_00992 3.6e-157 yckB ET Belongs to the bacterial solute-binding protein 3 family
PGIHDHAF_00993 1e-117 yecS E ABC transporter permease
PGIHDHAF_00994 1.2e-261 nylA 3.5.1.4 J Belongs to the amidase family
PGIHDHAF_00995 8.1e-127 arcD S C4-dicarboxylate anaerobic carrier
PGIHDHAF_00996 1.9e-214 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PGIHDHAF_00997 8.9e-83 F Hydrolase, NUDIX family
PGIHDHAF_00998 1.4e-212 S Type IV secretion-system coupling protein DNA-binding domain
PGIHDHAF_00999 0.0 tetP J elongation factor G
PGIHDHAF_01000 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PGIHDHAF_01001 6e-111 ypsA S Belongs to the UPF0398 family
PGIHDHAF_01002 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PGIHDHAF_01003 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PGIHDHAF_01004 3.7e-160 EG EamA-like transporter family
PGIHDHAF_01005 2.4e-192 C Aldo keto reductase family protein
PGIHDHAF_01006 1.3e-121 ypuA S Protein of unknown function (DUF1002)
PGIHDHAF_01007 2e-132 dnaD L DnaD domain protein
PGIHDHAF_01008 2.1e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PGIHDHAF_01009 1.6e-88 ypmB S Protein conserved in bacteria
PGIHDHAF_01010 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PGIHDHAF_01011 4.9e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PGIHDHAF_01012 2.4e-181 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PGIHDHAF_01013 1e-209 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PGIHDHAF_01014 2.9e-204 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PGIHDHAF_01015 9.5e-96 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGIHDHAF_01016 1.3e-103 pstA P Phosphate transport system permease protein PstA
PGIHDHAF_01017 2.4e-98 pstC P probably responsible for the translocation of the substrate across the membrane
PGIHDHAF_01018 9e-92 pstS P Phosphate
PGIHDHAF_01019 4.1e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PGIHDHAF_01020 1.3e-153 yitU 3.1.3.104 S hydrolase
PGIHDHAF_01021 1.2e-166 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PGIHDHAF_01022 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PGIHDHAF_01023 3.3e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PGIHDHAF_01024 3.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PGIHDHAF_01025 5.6e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PGIHDHAF_01026 1.8e-19 ycsI S Protein of unknown function (DUF1445)
PGIHDHAF_01027 4.5e-47 ycsI S Protein of unknown function (DUF1445)
PGIHDHAF_01028 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
PGIHDHAF_01030 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PGIHDHAF_01031 2.2e-260 yfnA E Amino Acid
PGIHDHAF_01032 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PGIHDHAF_01033 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PGIHDHAF_01034 5.4e-40 ylqC S Belongs to the UPF0109 family
PGIHDHAF_01035 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PGIHDHAF_01036 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
PGIHDHAF_01037 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PGIHDHAF_01038 9.4e-153 pstA P Phosphate transport system permease protein PstA
PGIHDHAF_01039 3.3e-153 pstC P probably responsible for the translocation of the substrate across the membrane
PGIHDHAF_01040 5.1e-159 pstS P Phosphate
PGIHDHAF_01041 2.6e-129 K Transcriptional regulatory protein, C-terminal domain protein
PGIHDHAF_01042 6.4e-41 L Transposase, IS116 IS110 IS902 family
PGIHDHAF_01043 2.8e-282 ysaB V FtsX-like permease family
PGIHDHAF_01044 7.1e-117 macB2 V ABC transporter, ATP-binding protein
PGIHDHAF_01045 3.7e-105 T Histidine kinase-like ATPases
PGIHDHAF_01046 5.6e-97 K response regulator
PGIHDHAF_01047 1.4e-116 bm3R1 K Bacterial regulatory proteins, tetR family
PGIHDHAF_01048 0.0 yhcA V ABC transporter, ATP-binding protein
PGIHDHAF_01049 4.7e-50 S FMN_bind
PGIHDHAF_01050 1.2e-66 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PGIHDHAF_01051 9.7e-135 P nitric oxide dioxygenase activity
PGIHDHAF_01052 3e-49 XK27_08850 S Aminoacyl-tRNA editing domain
PGIHDHAF_01053 7.7e-169 M Membrane
PGIHDHAF_01054 8e-20 XK27_06785 V ABC transporter
PGIHDHAF_01055 1.4e-101 K Transcriptional regulator
PGIHDHAF_01056 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PGIHDHAF_01057 2.1e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PGIHDHAF_01058 1.2e-260 argH 4.3.2.1 E argininosuccinate lyase
PGIHDHAF_01059 2.2e-20 lacA S transferase hexapeptide repeat
PGIHDHAF_01060 5.9e-157 L Thioesterase-like superfamily
PGIHDHAF_01061 3.4e-11 S NADPH-dependent FMN reductase
PGIHDHAF_01062 2.9e-31 S NADPH-dependent FMN reductase
PGIHDHAF_01063 5.2e-241 yfnA E amino acid
PGIHDHAF_01064 6.7e-243 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PGIHDHAF_01066 2.2e-152 mleP3 S Membrane transport protein
PGIHDHAF_01067 1.1e-52 trxA O Belongs to the thioredoxin family
PGIHDHAF_01068 2e-255 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
PGIHDHAF_01069 1.6e-208 EGP Major facilitator Superfamily
PGIHDHAF_01070 1e-210 ycsG P Natural resistance-associated macrophage protein
PGIHDHAF_01071 1.7e-134 ycsF S LamB/YcsF family
PGIHDHAF_01072 4.9e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PGIHDHAF_01073 1.9e-58 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PGIHDHAF_01074 1.4e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
PGIHDHAF_01075 4.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
PGIHDHAF_01076 2.3e-72 K helix_turn_helix, mercury resistance
PGIHDHAF_01077 1.7e-81 S Psort location Cytoplasmic, score
PGIHDHAF_01078 5e-287 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
PGIHDHAF_01079 1.1e-95 wecD K Acetyltransferase (GNAT) family
PGIHDHAF_01080 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
PGIHDHAF_01081 1.1e-194 asnA 6.3.1.1 F aspartate--ammonia ligase
PGIHDHAF_01082 2.4e-35 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PGIHDHAF_01083 4.9e-215 2.1.1.14 E methionine synthase, vitamin-B12 independent
PGIHDHAF_01084 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PGIHDHAF_01085 3.5e-38 S Cytochrome B5
PGIHDHAF_01088 1.6e-15 S Domain of unknown function (DUF4811)
PGIHDHAF_01089 2.8e-255 lmrB EGP Major facilitator Superfamily
PGIHDHAF_01090 7.7e-97 K transcriptional regulator
PGIHDHAF_01091 3.2e-71 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
PGIHDHAF_01092 0.0 L Helicase C-terminal domain protein
PGIHDHAF_01093 1.6e-54 S MazG-like family
PGIHDHAF_01094 6.1e-108 lssY 3.6.1.27 I Acid phosphatase homologues
PGIHDHAF_01095 1e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PGIHDHAF_01096 2e-97
PGIHDHAF_01097 5.8e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PGIHDHAF_01098 1.1e-167 ponA V Beta-lactamase enzyme family
PGIHDHAF_01099 6.2e-266 yjeM E Amino Acid
PGIHDHAF_01101 3.9e-110
PGIHDHAF_01102 1.5e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
PGIHDHAF_01103 3.2e-164 K LysR substrate binding domain
PGIHDHAF_01104 7.3e-261 S Uncharacterized protein conserved in bacteria (DUF2252)
PGIHDHAF_01105 2e-296 scrB 3.2.1.26 GH32 G invertase
PGIHDHAF_01106 1.2e-196 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
PGIHDHAF_01107 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
PGIHDHAF_01108 3.6e-108 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGIHDHAF_01109 5.7e-177 L Transposase and inactivated derivatives, IS30 family
PGIHDHAF_01110 2.2e-49 yqeB S Pyrimidine dimer DNA glycosylase
PGIHDHAF_01111 1.9e-26 tnp L DDE domain
PGIHDHAF_01112 1.5e-124 S EcsC protein family
PGIHDHAF_01113 5.3e-79 mleR K LysR family
PGIHDHAF_01114 5.5e-231 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PGIHDHAF_01115 6e-183 XK27_09615 S reductase
PGIHDHAF_01116 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
PGIHDHAF_01117 6.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PGIHDHAF_01118 3.6e-215 frdC 1.3.5.4 C FAD binding domain
PGIHDHAF_01119 1.9e-224 yflS P Sodium:sulfate symporter transmembrane region
PGIHDHAF_01120 1.1e-161 mleR K LysR family transcriptional regulator
PGIHDHAF_01121 1.9e-253 yjjP S Putative threonine/serine exporter
PGIHDHAF_01122 2.7e-120 ung2 3.2.2.27 L Uracil-DNA glycosylase
PGIHDHAF_01123 9.1e-189 I Alpha beta
PGIHDHAF_01124 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PGIHDHAF_01125 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PGIHDHAF_01127 2.5e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PGIHDHAF_01128 8.5e-150 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PGIHDHAF_01129 2.2e-112 S Domain of unknown function (DUF4811)
PGIHDHAF_01130 6.6e-268 lmrB EGP Major facilitator Superfamily
PGIHDHAF_01131 1.9e-74 merR K MerR HTH family regulatory protein
PGIHDHAF_01132 2e-58
PGIHDHAF_01133 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGIHDHAF_01134 2.2e-216 S CAAX protease self-immunity
PGIHDHAF_01135 8.1e-33 elaA S GNAT family
PGIHDHAF_01136 4.5e-85 usp1 T Belongs to the universal stress protein A family
PGIHDHAF_01137 4.5e-110 S VIT family
PGIHDHAF_01138 2.5e-116 S membrane
PGIHDHAF_01139 1.7e-162 czcD P cation diffusion facilitator family transporter
PGIHDHAF_01140 1.2e-123 sirR K iron dependent repressor
PGIHDHAF_01141 1.3e-30 cspA K Cold shock protein
PGIHDHAF_01142 3.7e-126 thrE S Putative threonine/serine exporter
PGIHDHAF_01143 3.7e-82 S Threonine/Serine exporter, ThrE
PGIHDHAF_01144 2.6e-115 lssY 3.6.1.27 I phosphatase
PGIHDHAF_01145 8.3e-156 I alpha/beta hydrolase fold
PGIHDHAF_01147 1.9e-267 lysP E amino acid
PGIHDHAF_01148 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PGIHDHAF_01154 2e-11 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGIHDHAF_01155 6.9e-18 IQ reductase
PGIHDHAF_01156 1.6e-32 IQ reductase
PGIHDHAF_01157 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PGIHDHAF_01158 1.8e-53 S ABC-type cobalt transport system, permease component
PGIHDHAF_01160 2.7e-120 J 2'-5' RNA ligase superfamily
PGIHDHAF_01161 1.9e-132 XK27_07210 6.1.1.6 S B3 4 domain
PGIHDHAF_01162 9.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
PGIHDHAF_01163 4.8e-79 ctsR K Belongs to the CtsR family
PGIHDHAF_01164 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PGIHDHAF_01165 5.8e-106 K Bacterial regulatory proteins, tetR family
PGIHDHAF_01166 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGIHDHAF_01167 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGIHDHAF_01168 5.6e-135 puuD S peptidase C26
PGIHDHAF_01169 2.2e-213 ykiI
PGIHDHAF_01170 2.8e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
PGIHDHAF_01171 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PGIHDHAF_01172 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PGIHDHAF_01173 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PGIHDHAF_01174 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PGIHDHAF_01175 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PGIHDHAF_01176 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
PGIHDHAF_01177 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PGIHDHAF_01178 3.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PGIHDHAF_01179 1.9e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PGIHDHAF_01180 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PGIHDHAF_01181 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PGIHDHAF_01182 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PGIHDHAF_01183 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
PGIHDHAF_01184 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PGIHDHAF_01185 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PGIHDHAF_01186 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PGIHDHAF_01187 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PGIHDHAF_01188 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGIHDHAF_01189 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PGIHDHAF_01190 5.1e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PGIHDHAF_01191 1.5e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PGIHDHAF_01192 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PGIHDHAF_01193 2.5e-23 rpmD J Ribosomal protein L30
PGIHDHAF_01194 2.1e-65 rplO J Binds to the 23S rRNA
PGIHDHAF_01195 5.8e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PGIHDHAF_01196 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PGIHDHAF_01197 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PGIHDHAF_01198 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PGIHDHAF_01199 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PGIHDHAF_01200 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PGIHDHAF_01201 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGIHDHAF_01202 2.8e-61 rplQ J Ribosomal protein L17
PGIHDHAF_01203 1.7e-148 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGIHDHAF_01204 5.8e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGIHDHAF_01205 1.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGIHDHAF_01206 6.3e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PGIHDHAF_01207 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PGIHDHAF_01208 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PGIHDHAF_01209 2e-189 S interspecies interaction between organisms
PGIHDHAF_01210 1.2e-138 IQ reductase
PGIHDHAF_01211 2.2e-108 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
PGIHDHAF_01212 2.1e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PGIHDHAF_01213 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PGIHDHAF_01214 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PGIHDHAF_01215 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PGIHDHAF_01216 3.2e-166 camS S sex pheromone
PGIHDHAF_01217 1e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGIHDHAF_01218 5.7e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PGIHDHAF_01219 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGIHDHAF_01220 4.8e-185 yegS 2.7.1.107 G Lipid kinase
PGIHDHAF_01221 4.1e-264 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGIHDHAF_01222 1.4e-49 K TRANSCRIPTIONal
PGIHDHAF_01223 3.5e-82 K Helix-turn-helix XRE-family like proteins
PGIHDHAF_01224 1.2e-89 K Psort location CytoplasmicMembrane, score
PGIHDHAF_01225 6.1e-117 S Sel1-like repeats.
PGIHDHAF_01226 7.3e-64 yjbR S YjbR
PGIHDHAF_01227 1.3e-16
PGIHDHAF_01228 2.4e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PGIHDHAF_01229 1.5e-112 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PGIHDHAF_01230 7.2e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PGIHDHAF_01231 2.1e-23 D mRNA cleavage
PGIHDHAF_01232 9.7e-179 S Phosphotransferase system, EIIC
PGIHDHAF_01233 2.6e-115 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGIHDHAF_01235 7.2e-144 S Oxidoreductase family, NAD-binding Rossmann fold
PGIHDHAF_01237 3.2e-186 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PGIHDHAF_01238 3.9e-193 nhaC C Na H antiporter NhaC
PGIHDHAF_01240 1.2e-74 ddaH 3.5.3.18 E Amidinotransferase
PGIHDHAF_01241 7.1e-89 S Aminoacyl-tRNA editing domain
PGIHDHAF_01242 0.0 mco Q Multicopper oxidase
PGIHDHAF_01243 2.8e-51 K 2 iron, 2 sulfur cluster binding
PGIHDHAF_01244 9.6e-90 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PGIHDHAF_01245 2.8e-120 Q Methyltransferase domain
PGIHDHAF_01247 3.3e-101 S CAAX protease self-immunity
PGIHDHAF_01248 4.6e-99 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PGIHDHAF_01249 3.4e-28 fsr EGP Major Facilitator Superfamily
PGIHDHAF_01250 4.1e-36 fsr EGP Major Facilitator Superfamily
PGIHDHAF_01251 1.7e-48 fsr EGP Major Facilitator Superfamily
PGIHDHAF_01252 1.4e-101 K helix_turn_helix multiple antibiotic resistance protein
PGIHDHAF_01253 1.3e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PGIHDHAF_01254 1.6e-105
PGIHDHAF_01255 2e-85 dps P Belongs to the Dps family
PGIHDHAF_01256 8.2e-304 ybiT S ABC transporter, ATP-binding protein
PGIHDHAF_01257 7.8e-34 yneR S Belongs to the HesB IscA family
PGIHDHAF_01258 2.8e-140 S NADPH-dependent FMN reductase
PGIHDHAF_01259 1.2e-285 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PGIHDHAF_01260 2.1e-160 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PGIHDHAF_01261 2e-103 yvdD 3.2.2.10 S Belongs to the LOG family
PGIHDHAF_01262 4.9e-63 S Domain of unknown function (DUF4828)
PGIHDHAF_01263 6.4e-190 mocA S Oxidoreductase
PGIHDHAF_01264 8.9e-232 yfmL 3.6.4.13 L DEAD DEAH box helicase
PGIHDHAF_01267 3.9e-75 gtcA S Teichoic acid glycosylation protein
PGIHDHAF_01268 4.2e-77 fld C Flavodoxin
PGIHDHAF_01269 2.9e-167 map 3.4.11.18 E Methionine Aminopeptidase
PGIHDHAF_01270 0.0 XK27_08315 M Sulfatase
PGIHDHAF_01271 2.3e-138 yihY S Belongs to the UPF0761 family
PGIHDHAF_01272 3.8e-31 S Protein of unknown function (DUF2922)
PGIHDHAF_01273 1.3e-07
PGIHDHAF_01274 3.2e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
PGIHDHAF_01275 1.1e-118 rfbP M Bacterial sugar transferase
PGIHDHAF_01276 1.7e-147 cps1D M Domain of unknown function (DUF4422)
PGIHDHAF_01277 1.2e-94 cps3F
PGIHDHAF_01278 4.5e-45 M biosynthesis protein
PGIHDHAF_01279 2.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
PGIHDHAF_01280 9.3e-203 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PGIHDHAF_01281 3.3e-72 S enterobacterial common antigen metabolic process
PGIHDHAF_01282 2.9e-58 acmD M repeat protein
PGIHDHAF_01284 2.9e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PGIHDHAF_01285 8.1e-09
PGIHDHAF_01286 6e-65 M repeat protein
PGIHDHAF_01287 2.9e-118 yueF S AI-2E family transporter
PGIHDHAF_01288 2.6e-164 ykoT GT2 M Glycosyl transferase family 2
PGIHDHAF_01289 7.7e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PGIHDHAF_01290 6.2e-95 M transferase activity, transferring glycosyl groups
PGIHDHAF_01291 7e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
PGIHDHAF_01292 2.5e-88 S Bacterial membrane protein, YfhO
PGIHDHAF_01293 1.2e-171 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PGIHDHAF_01294 7.8e-64 gntR1 K Transcriptional regulator, GntR family
PGIHDHAF_01295 1.5e-155 V ABC transporter, ATP-binding protein
PGIHDHAF_01296 1.2e-14
PGIHDHAF_01297 1.2e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
PGIHDHAF_01298 6.5e-162 EG EamA-like transporter family
PGIHDHAF_01299 3.2e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGIHDHAF_01300 3.6e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
PGIHDHAF_01301 1.7e-97 S Pfam:DUF3816
PGIHDHAF_01302 2.5e-264 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGIHDHAF_01303 2.4e-109 pncA Q Isochorismatase family
PGIHDHAF_01304 4.9e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
PGIHDHAF_01305 0.0 clpE O Belongs to the ClpA ClpB family
PGIHDHAF_01307 4.7e-39 ptsH G phosphocarrier protein HPR
PGIHDHAF_01308 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PGIHDHAF_01309 5e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PGIHDHAF_01310 1.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
PGIHDHAF_01311 6.5e-182 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PGIHDHAF_01312 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
PGIHDHAF_01313 5.4e-50 ybjQ S Belongs to the UPF0145 family
PGIHDHAF_01314 1.2e-76 rocF 3.5.3.1, 3.5.3.11 E Arginase family
PGIHDHAF_01316 6.8e-136 1.3.1.9 S Nitronate monooxygenase
PGIHDHAF_01317 3.6e-28 1.3.1.9 S Nitronate monooxygenase
PGIHDHAF_01318 4.7e-54 K Helix-turn-helix domain
PGIHDHAF_01319 4.7e-105 S Domain of unknown function (DUF4767)
PGIHDHAF_01320 1.8e-74
PGIHDHAF_01321 9.3e-09 S Domain of unknown function (DUF4767)
PGIHDHAF_01322 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
PGIHDHAF_01323 0.0 norZ 1.7.2.5 P Cytochrome C and Quinol oxidase polypeptide I
PGIHDHAF_01324 3.7e-269 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PGIHDHAF_01325 1e-113 2.7.6.5 T Region found in RelA / SpoT proteins
PGIHDHAF_01326 3.1e-79 K response regulator
PGIHDHAF_01327 1.4e-130 sptS 2.7.13.3 T Histidine kinase
PGIHDHAF_01328 9.9e-99 L Belongs to the 'phage' integrase family
PGIHDHAF_01330 5.3e-08 K sequence-specific DNA binding
PGIHDHAF_01331 0.0 V Type II restriction enzyme, methylase subunits
PGIHDHAF_01332 1.9e-97 K IrrE N-terminal-like domain
PGIHDHAF_01334 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
PGIHDHAF_01335 3.3e-103 2.3.1.128 K acetyltransferase
PGIHDHAF_01336 9.1e-133 IQ Dehydrogenase reductase
PGIHDHAF_01337 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PGIHDHAF_01338 2.5e-161 EG EamA-like transporter family
PGIHDHAF_01339 0.0 helD 3.6.4.12 L DNA helicase
PGIHDHAF_01340 1.6e-117 dedA S SNARE associated Golgi protein
PGIHDHAF_01341 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PGIHDHAF_01342 5e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PGIHDHAF_01343 1.3e-207 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PGIHDHAF_01344 1.2e-134 pnuC H nicotinamide mononucleotide transporter
PGIHDHAF_01345 3e-298 ybeC E amino acid
PGIHDHAF_01346 8.7e-107 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGIHDHAF_01347 7.2e-142 mnaA 5.1.3.14 M UDP-N-acetylglucosamine 2-epimerase
PGIHDHAF_01348 1.3e-122 G Glycosyl hydrolases family 8
PGIHDHAF_01349 3.8e-163 ydaM M Glycosyl transferase family group 2
PGIHDHAF_01351 1.1e-78
PGIHDHAF_01352 2.8e-138 V domain protein
PGIHDHAF_01353 4e-96 V domain protein
PGIHDHAF_01354 1.5e-92 K Transcriptional regulator (TetR family)
PGIHDHAF_01355 3.1e-187 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PGIHDHAF_01356 4.4e-169
PGIHDHAF_01358 7.5e-82 zur P Belongs to the Fur family
PGIHDHAF_01359 3.7e-105 gmk2 2.7.4.8 F Guanylate kinase
PGIHDHAF_01360 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
PGIHDHAF_01361 1.1e-205 yfnA E Amino Acid
PGIHDHAF_01362 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PGIHDHAF_01363 1.4e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
PGIHDHAF_01364 6.6e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
PGIHDHAF_01365 9.4e-282 S Uncharacterized protein conserved in bacteria (DUF2325)
PGIHDHAF_01366 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
PGIHDHAF_01367 3.3e-169 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
PGIHDHAF_01368 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGIHDHAF_01369 4.1e-83 nrdI F NrdI Flavodoxin like
PGIHDHAF_01370 1.9e-109 M ErfK YbiS YcfS YnhG
PGIHDHAF_01372 4.7e-207 nrnB S DHHA1 domain
PGIHDHAF_01373 3.4e-291 S ABC transporter, ATP-binding protein
PGIHDHAF_01374 5.9e-180 ABC-SBP S ABC transporter
PGIHDHAF_01375 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PGIHDHAF_01376 1.2e-132 XK27_08845 S ABC transporter, ATP-binding protein
PGIHDHAF_01378 5.7e-225 amtB P ammonium transporter
PGIHDHAF_01379 8.6e-235 mepA V MATE efflux family protein
PGIHDHAF_01380 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PGIHDHAF_01381 7.4e-183 fruR3 K Transcriptional regulator, LacI family
PGIHDHAF_01382 1.1e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
PGIHDHAF_01383 1.1e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGIHDHAF_01384 1e-56 trxA1 O Belongs to the thioredoxin family
PGIHDHAF_01385 2.3e-142 terC P membrane
PGIHDHAF_01386 3.6e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PGIHDHAF_01387 2.3e-170 corA P CorA-like Mg2+ transporter protein
PGIHDHAF_01388 1.2e-228 pbuX F xanthine permease
PGIHDHAF_01389 7.2e-150 qorB 1.6.5.2 GM NmrA-like family
PGIHDHAF_01390 6.1e-125 pgm3 G phosphoglycerate mutase family
PGIHDHAF_01391 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PGIHDHAF_01392 2e-85
PGIHDHAF_01393 7.4e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PGIHDHAF_01394 2.3e-101 dps P Belongs to the Dps family
PGIHDHAF_01395 8.7e-34 copZ P Heavy-metal-associated domain
PGIHDHAF_01396 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PGIHDHAF_01397 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
PGIHDHAF_01398 2e-180 iunH2 3.2.2.1 F nucleoside hydrolase
PGIHDHAF_01399 2.7e-100 S ABC-type cobalt transport system, permease component
PGIHDHAF_01400 2.4e-256 cbiO1 S ABC transporter, ATP-binding protein
PGIHDHAF_01401 2.4e-113 P Cobalt transport protein
PGIHDHAF_01402 8.8e-17 yvlA
PGIHDHAF_01403 0.0 yjcE P Sodium proton antiporter
PGIHDHAF_01404 9e-192 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
PGIHDHAF_01405 2.7e-73 O OsmC-like protein
PGIHDHAF_01406 1.1e-186 D Alpha beta
PGIHDHAF_01407 8.4e-75 K Transcriptional regulator
PGIHDHAF_01408 2.2e-159
PGIHDHAF_01409 8.7e-20
PGIHDHAF_01410 1e-58
PGIHDHAF_01411 3.1e-75 uspA T universal stress protein
PGIHDHAF_01413 9.7e-130 qmcA O prohibitin homologues
PGIHDHAF_01414 5.5e-245 glpT G Major Facilitator Superfamily
PGIHDHAF_01415 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PGIHDHAF_01416 8.8e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
PGIHDHAF_01417 4.9e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PGIHDHAF_01418 4.8e-258 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PGIHDHAF_01419 9.8e-194 ulaA 2.7.1.194 S PTS system sugar-specific permease component
PGIHDHAF_01420 6.1e-40 ulaB 2.7.1.194 G Phosphotransferase system galactitol-specific IIB component
PGIHDHAF_01421 2.3e-43 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PGIHDHAF_01422 4.7e-131 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PGIHDHAF_01423 1.5e-108 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
PGIHDHAF_01424 1.3e-127 G Phosphotransferase System
PGIHDHAF_01425 3.8e-40 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
PGIHDHAF_01426 2.2e-52 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PGIHDHAF_01427 1.9e-18 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PGIHDHAF_01428 4.8e-133 manR K PRD domain
PGIHDHAF_01429 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PGIHDHAF_01430 1e-243 fucP G Major Facilitator Superfamily
PGIHDHAF_01431 1.3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PGIHDHAF_01432 5e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGIHDHAF_01433 9.2e-170 deoR K sugar-binding domain protein
PGIHDHAF_01434 1.1e-113 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PGIHDHAF_01435 1.1e-200 S Domain of unknown function (DUF4432)
PGIHDHAF_01436 3.2e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGIHDHAF_01437 3.7e-260 G PTS system Galactitol-specific IIC component
PGIHDHAF_01438 1.2e-188 K helix_turn _helix lactose operon repressor
PGIHDHAF_01439 1.1e-49 yjeM E Amino Acid
PGIHDHAF_01440 7.1e-30 yjeM E Amino Acid
PGIHDHAF_01441 6e-106 yjeM E Amino Acid
PGIHDHAF_01442 3.8e-33 yjeM E Amino Acid
PGIHDHAF_01444 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PGIHDHAF_01445 3.3e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
PGIHDHAF_01446 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
PGIHDHAF_01447 7.1e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PGIHDHAF_01448 1.2e-129
PGIHDHAF_01449 2.3e-265 pipD E Dipeptidase
PGIHDHAF_01450 2.9e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
PGIHDHAF_01451 2.6e-86 M1-874 K Domain of unknown function (DUF1836)
PGIHDHAF_01452 3e-90 GM epimerase
PGIHDHAF_01453 3.6e-252 yhdP S Transporter associated domain
PGIHDHAF_01454 2.4e-83 nrdI F Belongs to the NrdI family
PGIHDHAF_01455 9.4e-74 S 3-demethylubiquinone-9 3-methyltransferase
PGIHDHAF_01456 1.3e-205 yeaN P Transporter, major facilitator family protein
PGIHDHAF_01457 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PGIHDHAF_01458 1.2e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PGIHDHAF_01459 1e-81 uspA T universal stress protein
PGIHDHAF_01460 3e-78 K AsnC family
PGIHDHAF_01461 4.2e-141 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGIHDHAF_01462 1.1e-178 K helix_turn _helix lactose operon repressor
PGIHDHAF_01463 0.0 pepF E oligoendopeptidase F
PGIHDHAF_01464 7.1e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PGIHDHAF_01465 7e-124 S Membrane
PGIHDHAF_01466 1.7e-161 hrtB V ABC transporter permease
PGIHDHAF_01467 4.5e-115 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PGIHDHAF_01468 4.5e-103 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PGIHDHAF_01469 3.4e-191 L Transposase and inactivated derivatives, IS30 family
PGIHDHAF_01470 1.2e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
PGIHDHAF_01471 0.0 cadA 3.6.3.3, 3.6.3.5 P Cadmium transporter
PGIHDHAF_01472 1.9e-109 L Transposase and inactivated derivatives, IS30 family
PGIHDHAF_01473 1.2e-61 L Transposase DDE domain
PGIHDHAF_01474 8.6e-276 lacS G Transporter
PGIHDHAF_01475 0.0 rafA 3.2.1.22 G alpha-galactosidase
PGIHDHAF_01476 1.1e-127 galR K Transcriptional regulator
PGIHDHAF_01477 3.3e-40 galR K Transcriptional regulator
PGIHDHAF_01478 4e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PGIHDHAF_01479 3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PGIHDHAF_01480 1.2e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
PGIHDHAF_01481 1.6e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
PGIHDHAF_01482 3.6e-96 yxkA S Phosphatidylethanolamine-binding protein
PGIHDHAF_01483 6.9e-36
PGIHDHAF_01484 6.6e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PGIHDHAF_01485 5.3e-119 tcyB U Binding-protein-dependent transport system inner membrane component
PGIHDHAF_01486 5.7e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PGIHDHAF_01487 5.9e-52
PGIHDHAF_01488 3.1e-170 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGIHDHAF_01489 1.7e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PGIHDHAF_01490 6.9e-147 pnuC H nicotinamide mononucleotide transporter
PGIHDHAF_01491 1.1e-92 ymdB S Macro domain protein
PGIHDHAF_01492 0.0 pepO 3.4.24.71 O Peptidase family M13
PGIHDHAF_01493 1.8e-229 pbuG S permease
PGIHDHAF_01494 2.5e-46
PGIHDHAF_01495 1.2e-211 S Putative metallopeptidase domain
PGIHDHAF_01496 1.8e-204 3.1.3.1 S associated with various cellular activities
PGIHDHAF_01497 1.3e-116 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PGIHDHAF_01498 2.4e-65 yeaO S Protein of unknown function, DUF488
PGIHDHAF_01500 4.8e-125 yrkL S Flavodoxin-like fold
PGIHDHAF_01501 5.6e-55
PGIHDHAF_01502 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
PGIHDHAF_01503 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PGIHDHAF_01504 4.1e-102
PGIHDHAF_01505 9.5e-26
PGIHDHAF_01506 2e-169 scrR K Transcriptional regulator, LacI family
PGIHDHAF_01507 4.2e-43 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PGIHDHAF_01508 1e-84 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PGIHDHAF_01509 2.6e-46 czrA K Transcriptional regulator, ArsR family
PGIHDHAF_01510 1.8e-75 argR K Regulates arginine biosynthesis genes
PGIHDHAF_01511 5.5e-124 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PGIHDHAF_01512 8.6e-158 hrtB V ABC transporter permease
PGIHDHAF_01513 3.7e-108 ygfC K Bacterial regulatory proteins, tetR family
PGIHDHAF_01514 2.4e-189 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
PGIHDHAF_01515 9.7e-278 mntH P H( )-stimulated, divalent metal cation uptake system
PGIHDHAF_01516 2.1e-20
PGIHDHAF_01517 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PGIHDHAF_01518 1.2e-69 L nuclease
PGIHDHAF_01519 2.9e-162 F DNA/RNA non-specific endonuclease
PGIHDHAF_01520 6.6e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PGIHDHAF_01521 6.9e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PGIHDHAF_01522 8e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PGIHDHAF_01523 0.0 asnB 6.3.5.4 E Asparagine synthase
PGIHDHAF_01524 1.5e-219 lysP E amino acid
PGIHDHAF_01525 7e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PGIHDHAF_01526 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PGIHDHAF_01527 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PGIHDHAF_01528 4.8e-154 jag S R3H domain protein
PGIHDHAF_01529 3.4e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGIHDHAF_01530 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PGIHDHAF_01531 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PGIHDHAF_01533 5.2e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PGIHDHAF_01534 1.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PGIHDHAF_01535 2.2e-34 yaaA S S4 domain protein YaaA
PGIHDHAF_01536 1.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PGIHDHAF_01537 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGIHDHAF_01538 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGIHDHAF_01539 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
PGIHDHAF_01540 6.4e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PGIHDHAF_01541 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PGIHDHAF_01542 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PGIHDHAF_01543 1.2e-74 rplI J Binds to the 23S rRNA
PGIHDHAF_01544 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PGIHDHAF_01545 1e-207 lmrP E Major Facilitator Superfamily
PGIHDHAF_01546 9.2e-61
PGIHDHAF_01549 6.8e-130 K response regulator
PGIHDHAF_01550 0.0 vicK 2.7.13.3 T Histidine kinase
PGIHDHAF_01551 2.1e-238 yycH S YycH protein
PGIHDHAF_01552 2.7e-143 yycI S YycH protein
PGIHDHAF_01553 6e-154 vicX 3.1.26.11 S domain protein
PGIHDHAF_01554 1.2e-206 htrA 3.4.21.107 O serine protease
PGIHDHAF_01555 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PGIHDHAF_01556 5.7e-71 K Transcriptional regulator
PGIHDHAF_01557 1.4e-175 malR K Transcriptional regulator, LacI family
PGIHDHAF_01558 1.6e-249 malT G Major Facilitator
PGIHDHAF_01559 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PGIHDHAF_01560 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PGIHDHAF_01561 2.5e-110 ysdA CP transmembrane transport
PGIHDHAF_01562 6.2e-190 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PGIHDHAF_01563 1e-181 D Alpha beta
PGIHDHAF_01564 3.1e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGIHDHAF_01565 2.1e-216 patA 2.6.1.1 E Aminotransferase
PGIHDHAF_01566 1e-34
PGIHDHAF_01567 0.0 clpL O associated with various cellular activities
PGIHDHAF_01568 2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGIHDHAF_01569 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PGIHDHAF_01570 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PGIHDHAF_01571 2.6e-163 yvgN C Aldo keto reductase
PGIHDHAF_01572 3.6e-291 glpQ 3.1.4.46 C phosphodiesterase
PGIHDHAF_01573 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
PGIHDHAF_01574 1.3e-188 ybhR V ABC transporter
PGIHDHAF_01575 1.6e-126 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
PGIHDHAF_01576 4e-93 K transcriptional regulator
PGIHDHAF_01577 2.8e-166 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PGIHDHAF_01578 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PGIHDHAF_01579 1.3e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PGIHDHAF_01580 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PGIHDHAF_01581 1.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PGIHDHAF_01582 1.1e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PGIHDHAF_01583 1.2e-16 gntT EG gluconate transmembrane transporter activity
PGIHDHAF_01584 6.9e-47
PGIHDHAF_01585 1.9e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
PGIHDHAF_01586 3.5e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
PGIHDHAF_01587 3.5e-149 metQ1 P Belongs to the nlpA lipoprotein family
PGIHDHAF_01588 1.8e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PGIHDHAF_01589 1.2e-97 metI P ABC transporter permease
PGIHDHAF_01590 2.6e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PGIHDHAF_01591 3.1e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGIHDHAF_01592 1.6e-196 brnQ U Component of the transport system for branched-chain amino acids
PGIHDHAF_01593 1.1e-122 iolS C Aldo keto reductase
PGIHDHAF_01594 9.9e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PGIHDHAF_01595 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGIHDHAF_01596 7e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
PGIHDHAF_01597 1.6e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGIHDHAF_01599 3.7e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PGIHDHAF_01600 0.0 sbcC L Putative exonuclease SbcCD, C subunit
PGIHDHAF_01601 5.7e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PGIHDHAF_01602 2.5e-15 tlpA2 L Transposase IS200 like
PGIHDHAF_01603 1.7e-203 L transposase, IS605 OrfB family
PGIHDHAF_01605 5.5e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PGIHDHAF_01607 1.7e-223 glnP P ABC transporter
PGIHDHAF_01608 1e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PGIHDHAF_01609 6.4e-249 cycA E Amino acid permease
PGIHDHAF_01610 2.9e-213 nupG F Nucleoside transporter
PGIHDHAF_01611 2.2e-144 rihC 3.2.2.1 F Nucleoside
PGIHDHAF_01612 3.4e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PGIHDHAF_01613 1.7e-157 noc K Belongs to the ParB family
PGIHDHAF_01614 5.6e-147 spo0J K Belongs to the ParB family
PGIHDHAF_01615 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
PGIHDHAF_01616 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PGIHDHAF_01617 9.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
PGIHDHAF_01618 1.7e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PGIHDHAF_01619 1.4e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PGIHDHAF_01620 6.1e-132 epsB M biosynthesis protein
PGIHDHAF_01621 5.5e-114 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PGIHDHAF_01622 3.9e-139 ywqE 3.1.3.48 GM PHP domain protein
PGIHDHAF_01623 8e-90 capM M Bacterial sugar transferase
PGIHDHAF_01624 7.2e-84 GT4 G Glycosyl transferase 4-like
PGIHDHAF_01625 1.5e-35 S COG0463 Glycosyltransferases involved in cell wall biogenesis
PGIHDHAF_01626 2.1e-81
PGIHDHAF_01628 5.8e-36 M Glycosyltransferase like family 2
PGIHDHAF_01629 5.5e-225 aadAT EK Aminotransferase, class I
PGIHDHAF_01630 4.7e-159 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PGIHDHAF_01631 2.2e-143 ET Bacterial periplasmic substrate-binding proteins
PGIHDHAF_01633 3.9e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
PGIHDHAF_01635 2.1e-94 padC Q Phenolic acid decarboxylase
PGIHDHAF_01636 8.3e-99 padR K Virulence activator alpha C-term
PGIHDHAF_01637 3.4e-79 ndk 2.7.4.6 F Belongs to the NDK family
PGIHDHAF_01638 1.2e-24 S SNARE associated Golgi protein
PGIHDHAF_01639 2.8e-13 S SNARE associated Golgi protein
PGIHDHAF_01640 9.5e-236 N Uncharacterized conserved protein (DUF2075)
PGIHDHAF_01641 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PGIHDHAF_01643 1.9e-253 yifK E Amino acid permease
PGIHDHAF_01645 9.2e-60 pipD E Dipeptidase
PGIHDHAF_01646 8.2e-187 pipD E Dipeptidase
PGIHDHAF_01647 1.9e-161 endA F DNA RNA non-specific endonuclease
PGIHDHAF_01648 3.2e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PGIHDHAF_01649 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGIHDHAF_01650 7e-153 S Alpha/beta hydrolase of unknown function (DUF915)
PGIHDHAF_01652 3.5e-227
PGIHDHAF_01653 9e-195 V Beta-lactamase
PGIHDHAF_01654 3.2e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
PGIHDHAF_01655 3.8e-123 S membrane transporter protein
PGIHDHAF_01656 5.6e-179 S AI-2E family transporter
PGIHDHAF_01657 3.3e-214 phbA 2.3.1.9 I Belongs to the thiolase family
PGIHDHAF_01658 4.1e-161 rssA S Phospholipase, patatin family
PGIHDHAF_01659 9.9e-166 K LysR substrate binding domain
PGIHDHAF_01660 0.0 1.3.5.4 C FAD binding domain
PGIHDHAF_01661 5.7e-74 S Domain of unknown function (DUF4352)
PGIHDHAF_01662 4e-13 S Domain of unknown function (DUF4352)
PGIHDHAF_01663 2.7e-112 yicL EG EamA-like transporter family
PGIHDHAF_01664 1.1e-62
PGIHDHAF_01665 1.5e-34
PGIHDHAF_01666 2.1e-67 S pyridoxamine 5-phosphate
PGIHDHAF_01667 2.8e-179 yobV1 K WYL domain
PGIHDHAF_01668 2.3e-243 XK27_08635 S UPF0210 protein
PGIHDHAF_01669 2.5e-40 gcvR T Belongs to the UPF0237 family
PGIHDHAF_01670 3.7e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PGIHDHAF_01671 1e-212 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PGIHDHAF_01672 7.2e-208 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
PGIHDHAF_01673 5e-218 G Transporter, major facilitator family protein
PGIHDHAF_01674 3.4e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PGIHDHAF_01675 5.3e-158 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PGIHDHAF_01676 4.3e-62 ydiI Q Thioesterase superfamily
PGIHDHAF_01677 1e-34 citG 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PGIHDHAF_01678 2e-11 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PGIHDHAF_01680 7.8e-20 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PGIHDHAF_01681 1e-73 ydjP I Alpha/beta hydrolase family
PGIHDHAF_01682 2.1e-40 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGIHDHAF_01683 4.4e-08 L PFAM Integrase catalytic region
PGIHDHAF_01684 3.4e-260 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PGIHDHAF_01685 1e-27 XK27_02560 S Pfam:DUF59
PGIHDHAF_01686 4.4e-127 yocS S Transporter
PGIHDHAF_01687 5.8e-239 ydjE EGP Major facilitator Superfamily
PGIHDHAF_01688 1.1e-195 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PGIHDHAF_01689 9.3e-280 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGIHDHAF_01690 3.3e-106 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGIHDHAF_01691 2e-146 sua5 2.7.7.87 J Telomere recombination
PGIHDHAF_01693 3.8e-29 ybbM S Uncharacterised protein family (UPF0014)
PGIHDHAF_01695 5.3e-58 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PGIHDHAF_01696 1.4e-27 IQ oxidoreductase activity
PGIHDHAF_01698 3.2e-49 C Flavodoxin
PGIHDHAF_01699 1.8e-159 yicL EG EamA-like transporter family
PGIHDHAF_01700 3.9e-107 L Integrase
PGIHDHAF_01701 3.3e-45 K transcriptional regulator
PGIHDHAF_01702 1.3e-66 GM NmrA-like family
PGIHDHAF_01703 9.1e-27 C Flavodoxin
PGIHDHAF_01704 1.1e-74 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PGIHDHAF_01705 4.2e-74 O OsmC-like protein
PGIHDHAF_01706 1.8e-75 K Transcriptional regulator
PGIHDHAF_01707 1.7e-162 proX M ABC transporter, substrate-binding protein, QAT family
PGIHDHAF_01708 1.8e-108 proWZ P ABC transporter permease
PGIHDHAF_01709 2.7e-140 proV E ABC transporter, ATP-binding protein
PGIHDHAF_01710 3.1e-102 proW P ABC transporter, permease protein
PGIHDHAF_01711 5.8e-146 C Zinc-binding dehydrogenase
PGIHDHAF_01712 3.1e-195 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
PGIHDHAF_01713 8.5e-226 4.4.1.8 E Aminotransferase, class I
PGIHDHAF_01714 9.4e-180 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PGIHDHAF_01715 9.2e-203 xerS L Belongs to the 'phage' integrase family
PGIHDHAF_01716 6.5e-96 ywkB S Membrane transport protein
PGIHDHAF_01717 3e-237 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
PGIHDHAF_01718 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PGIHDHAF_01719 2.6e-80 hmpT S ECF-type riboflavin transporter, S component
PGIHDHAF_01720 4.7e-165 1.1.1.346 C Aldo keto reductase
PGIHDHAF_01721 2.9e-160 S DUF218 domain
PGIHDHAF_01722 5.9e-94 K Acetyltransferase (GNAT) domain
PGIHDHAF_01723 1.1e-163 I alpha/beta hydrolase fold
PGIHDHAF_01724 4e-116 S Phage minor capsid protein 2
PGIHDHAF_01727 2.5e-214 2.6.1.1 E Aminotransferase
PGIHDHAF_01728 2.2e-94 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
PGIHDHAF_01729 1.5e-29 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
PGIHDHAF_01730 7e-248 EGP Sugar (and other) transporter
PGIHDHAF_01731 4.6e-97 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
PGIHDHAF_01732 1.2e-91 S Fic/DOC family
PGIHDHAF_01733 4.4e-71 yncA 2.3.1.79 S Maltose acetyltransferase
PGIHDHAF_01734 2e-104 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PGIHDHAF_01735 4.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PGIHDHAF_01736 1.3e-263 arcD E Amino acid permease
PGIHDHAF_01737 4.2e-17 lmrB EGP Major facilitator Superfamily
PGIHDHAF_01739 4.6e-244 yhjX P Major Facilitator Superfamily
PGIHDHAF_01740 1.7e-117 S Protein of unknown function (DUF554)
PGIHDHAF_01741 1.4e-256 rarA L recombination factor protein RarA
PGIHDHAF_01743 0.0 oppD EP Psort location Cytoplasmic, score
PGIHDHAF_01744 1e-242 codA 3.5.4.1 F cytosine deaminase
PGIHDHAF_01745 9.4e-245 U Belongs to the purine-cytosine permease (2.A.39) family
PGIHDHAF_01746 2.6e-42 yebR 1.8.4.14 T GAF domain-containing protein
PGIHDHAF_01747 5.7e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
PGIHDHAF_01748 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PGIHDHAF_01749 6.8e-71 yqkB S Belongs to the HesB IscA family
PGIHDHAF_01750 3.6e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
PGIHDHAF_01751 5.2e-95 S Protein of unknown function (DUF1440)
PGIHDHAF_01752 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGIHDHAF_01753 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGIHDHAF_01754 1.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PGIHDHAF_01755 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
PGIHDHAF_01756 4.7e-154 D DNA integration
PGIHDHAF_01757 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGIHDHAF_01758 3.1e-164 dprA LU DNA protecting protein DprA
PGIHDHAF_01759 2.1e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGIHDHAF_01760 3.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PGIHDHAF_01761 3.1e-36 yozE S Belongs to the UPF0346 family
PGIHDHAF_01762 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PGIHDHAF_01763 1.1e-167 ypmR E lipolytic protein G-D-S-L family
PGIHDHAF_01764 3.2e-107 cat S Bacterial transferase hexapeptide (six repeats)
PGIHDHAF_01765 2.9e-218 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
PGIHDHAF_01766 6.8e-153 DegV S EDD domain protein, DegV family
PGIHDHAF_01767 1.2e-109 hlyIII S protein, hemolysin III
PGIHDHAF_01768 8.7e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PGIHDHAF_01769 6.8e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PGIHDHAF_01770 0.0 yfmR S ABC transporter, ATP-binding protein
PGIHDHAF_01771 2.6e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PGIHDHAF_01772 4.7e-165 xerD L Phage integrase, N-terminal SAM-like domain
PGIHDHAF_01773 1.8e-234 S Tetratricopeptide repeat protein
PGIHDHAF_01774 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PGIHDHAF_01775 3.7e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PGIHDHAF_01776 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
PGIHDHAF_01777 2e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PGIHDHAF_01778 9.7e-31 M Lysin motif
PGIHDHAF_01779 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
PGIHDHAF_01780 1.3e-198 ypbB 5.1.3.1 S Helix-turn-helix domain
PGIHDHAF_01781 3.7e-81 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PGIHDHAF_01782 2.8e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PGIHDHAF_01783 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PGIHDHAF_01784 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PGIHDHAF_01785 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGIHDHAF_01786 6e-160 xerD D recombinase XerD
PGIHDHAF_01787 4.7e-168 cvfB S S1 domain
PGIHDHAF_01788 2.4e-267 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PGIHDHAF_01789 0.0 dnaE 2.7.7.7 L DNA polymerase
PGIHDHAF_01791 6.6e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PGIHDHAF_01792 1.7e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PGIHDHAF_01793 2.9e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
PGIHDHAF_01794 1.7e-117 ktrA P domain protein
PGIHDHAF_01795 6.7e-227 ktrB P Potassium uptake protein
PGIHDHAF_01796 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PGIHDHAF_01797 6.5e-218 patA 2.6.1.1 E Aminotransferase
PGIHDHAF_01798 8e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PGIHDHAF_01799 2.1e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PGIHDHAF_01800 1.3e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PGIHDHAF_01801 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PGIHDHAF_01802 2.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PGIHDHAF_01803 4.5e-263 lysC 2.7.2.4 E Belongs to the aspartokinase family
PGIHDHAF_01804 3.5e-180 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PGIHDHAF_01805 1.1e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PGIHDHAF_01806 3.8e-16
PGIHDHAF_01807 6e-12 S Transglycosylase associated protein
PGIHDHAF_01808 1e-69 S Asp23 family, cell envelope-related function
PGIHDHAF_01809 2.5e-87
PGIHDHAF_01810 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PGIHDHAF_01811 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PGIHDHAF_01812 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PGIHDHAF_01813 4.9e-187 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PGIHDHAF_01814 2.9e-156 recO L Involved in DNA repair and RecF pathway recombination
PGIHDHAF_01815 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PGIHDHAF_01816 3e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PGIHDHAF_01817 1.1e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PGIHDHAF_01818 8.5e-179 phoH T phosphate starvation-inducible protein PhoH
PGIHDHAF_01819 4.6e-71 yqeY S YqeY-like protein
PGIHDHAF_01820 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PGIHDHAF_01821 8.6e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
PGIHDHAF_01822 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PGIHDHAF_01823 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
PGIHDHAF_01824 4.4e-194 6.3.1.20 H Lipoate-protein ligase
PGIHDHAF_01825 4.8e-174 lytH 3.5.1.28 M Ami_3
PGIHDHAF_01826 4.4e-168 yniA G Phosphotransferase enzyme family
PGIHDHAF_01827 4.6e-174 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PGIHDHAF_01828 8e-247 mmuP E amino acid
PGIHDHAF_01829 1.8e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PGIHDHAF_01830 2.8e-213 hom1 1.1.1.3 E Homoserine dehydrogenase
PGIHDHAF_01832 8.5e-78 IQ KR domain
PGIHDHAF_01833 4.4e-25 IQ KR domain
PGIHDHAF_01834 3.1e-153 cjaA ET ABC transporter substrate-binding protein
PGIHDHAF_01835 1.1e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PGIHDHAF_01836 5.7e-94 P ABC transporter permease
PGIHDHAF_01837 5.4e-113 papP P ABC transporter, permease protein
PGIHDHAF_01839 1.1e-38 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PGIHDHAF_01840 1.3e-219 G PTS system sugar-specific permease component
PGIHDHAF_01841 1.1e-45 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PGIHDHAF_01842 2.6e-268 3.2.1.21 GH3 G hydrolase, family 3
PGIHDHAF_01843 4.3e-64 uhpT EGP Major facilitator Superfamily
PGIHDHAF_01844 6.1e-43 uhpT EGP Major facilitator Superfamily
PGIHDHAF_01845 5.9e-190 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
PGIHDHAF_01846 5.7e-159 EGP Major facilitator Superfamily
PGIHDHAF_01847 1.5e-66 rhaS11 K helix_turn_helix, arabinose operon control protein
PGIHDHAF_01848 1.6e-149 ET Bacterial periplasmic substrate-binding proteins
PGIHDHAF_01849 6.4e-104 yxeN U ABC transporter, permease protein
PGIHDHAF_01850 8.6e-09 P Binding-protein-dependent transport system inner membrane component
PGIHDHAF_01851 1.2e-21 P Binding-protein-dependent transport system inner membrane component
PGIHDHAF_01852 6.9e-133 tcyN 3.6.3.21 E ABC transporter
PGIHDHAF_01853 6.2e-185 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
PGIHDHAF_01855 2.8e-210 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PGIHDHAF_01856 5.1e-218 metC1 2.5.1.48, 4.4.1.8 E cystathionine
PGIHDHAF_01857 3.5e-85 slyA K Transcriptional regulator
PGIHDHAF_01858 2.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PGIHDHAF_01859 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PGIHDHAF_01860 4.4e-58
PGIHDHAF_01861 6.8e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PGIHDHAF_01862 1.8e-181 prmA J Ribosomal protein L11 methyltransferase
PGIHDHAF_01863 1.2e-54
PGIHDHAF_01865 3.3e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PGIHDHAF_01866 1.6e-219 L Probable transposase
PGIHDHAF_01867 4.7e-96 S integral membrane protein
PGIHDHAF_01868 7.7e-13 aes I esterase lipase
PGIHDHAF_01869 1.4e-36 S CRISPR-associated protein (Cas_Csn2)
PGIHDHAF_01870 4.9e-35 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PGIHDHAF_01871 1.9e-92 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PGIHDHAF_01872 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PGIHDHAF_01873 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PGIHDHAF_01874 2.5e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PGIHDHAF_01875 1.6e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PGIHDHAF_01876 1.1e-113 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PGIHDHAF_01877 1.5e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PGIHDHAF_01878 1.2e-68 psiE S Phosphate-starvation-inducible E
PGIHDHAF_01879 3.8e-38 V CAAX protease self-immunity
PGIHDHAF_01880 2.1e-215 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PGIHDHAF_01881 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
PGIHDHAF_01882 5.9e-76 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PGIHDHAF_01883 9.2e-36 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PGIHDHAF_01884 3.6e-09 K LysR substrate binding domain
PGIHDHAF_01885 4.7e-09 S ChrR Cupin-like domain
PGIHDHAF_01886 8.7e-98 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGIHDHAF_01887 1.2e-157 P Belongs to the nlpA lipoprotein family
PGIHDHAF_01888 8.4e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGIHDHAF_01889 3.2e-116 S Protein of unknown function (DUF554)
PGIHDHAF_01890 2e-101 P Cadmium resistance transporter
PGIHDHAF_01891 1.4e-220 iscS 2.8.1.7 E Aminotransferase class V
PGIHDHAF_01892 4.5e-13 S Psort location CytoplasmicMembrane, score
PGIHDHAF_01893 1.2e-52 T Transcriptional regulatory protein, C terminal
PGIHDHAF_01894 2.6e-61 T His Kinase A (phosphoacceptor) domain
PGIHDHAF_01895 8.5e-55 C FMN binding
PGIHDHAF_01896 5.9e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PGIHDHAF_01897 1.7e-105 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
PGIHDHAF_01898 1.7e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PGIHDHAF_01899 5.1e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PGIHDHAF_01900 2.1e-79 K 2 iron, 2 sulfur cluster binding
PGIHDHAF_01901 5.4e-266 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
PGIHDHAF_01902 3.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGIHDHAF_01903 9.2e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PGIHDHAF_01904 7.3e-83 C aldo keto reductase
PGIHDHAF_01905 7.5e-18 C aldo keto reductase
PGIHDHAF_01906 2.5e-112 3.1.3.73 G phosphoglycerate mutase
PGIHDHAF_01907 3.3e-09
PGIHDHAF_01908 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PGIHDHAF_01909 1.5e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PGIHDHAF_01910 9.9e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PGIHDHAF_01911 2.9e-56 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PGIHDHAF_01912 4.7e-140 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PGIHDHAF_01913 5.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PGIHDHAF_01914 6.1e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PGIHDHAF_01915 3.8e-102 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PGIHDHAF_01916 1.1e-229 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PGIHDHAF_01917 5.8e-109 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PGIHDHAF_01918 3.8e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PGIHDHAF_01919 8.9e-169 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
PGIHDHAF_01920 1.9e-50 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PGIHDHAF_01921 1.6e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PGIHDHAF_01922 1.6e-94 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PGIHDHAF_01924 5.5e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PGIHDHAF_01925 0.0 dnaK O Heat shock 70 kDa protein
PGIHDHAF_01926 6.9e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PGIHDHAF_01927 2.4e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PGIHDHAF_01928 1.6e-61
PGIHDHAF_01929 2.6e-242 cycA E Amino acid permease
PGIHDHAF_01930 4.1e-253 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
PGIHDHAF_01931 1.5e-96 D Alpha beta
PGIHDHAF_01932 4.9e-52 ypaA S Protein of unknown function (DUF1304)
PGIHDHAF_01933 3e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PGIHDHAF_01934 1.5e-25 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGIHDHAF_01935 8.8e-66 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
PGIHDHAF_01936 2.1e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
PGIHDHAF_01937 4.6e-09
PGIHDHAF_01938 4.4e-70 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PGIHDHAF_01939 1.2e-177 K Transcriptional regulator, LacI family
PGIHDHAF_01940 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
PGIHDHAF_01941 2.1e-252 G Major Facilitator
PGIHDHAF_01942 6.4e-249 EGP Major facilitator Superfamily
PGIHDHAF_01943 6e-185 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PGIHDHAF_01944 6.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PGIHDHAF_01945 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PGIHDHAF_01946 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PGIHDHAF_01947 3.2e-50 ylxQ J ribosomal protein
PGIHDHAF_01948 1.4e-47 ylxR K Protein of unknown function (DUF448)
PGIHDHAF_01949 3.7e-224 nusA K Participates in both transcription termination and antitermination
PGIHDHAF_01950 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
PGIHDHAF_01951 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PGIHDHAF_01952 2.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PGIHDHAF_01953 1.1e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PGIHDHAF_01954 1.2e-206 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PGIHDHAF_01955 8e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
PGIHDHAF_01956 1.9e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
PGIHDHAF_01957 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGIHDHAF_01958 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PGIHDHAF_01959 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PGIHDHAF_01960 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
PGIHDHAF_01961 1.3e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PGIHDHAF_01962 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PGIHDHAF_01963 1.6e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PGIHDHAF_01964 5.5e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PGIHDHAF_01965 1.1e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
PGIHDHAF_01966 8.7e-47 yazA L GIY-YIG catalytic domain protein
PGIHDHAF_01967 8e-137 yabB 2.1.1.223 L Methyltransferase small domain
PGIHDHAF_01968 3.3e-115 plsC 2.3.1.51 I Acyltransferase
PGIHDHAF_01969 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
PGIHDHAF_01970 9.2e-37 ynzC S UPF0291 protein
PGIHDHAF_01971 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PGIHDHAF_01972 8.7e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PGIHDHAF_01973 5.6e-122 lutA C Cysteine-rich domain
PGIHDHAF_01974 1.1e-244 lutB C 4Fe-4S dicluster domain
PGIHDHAF_01975 5.7e-87 yrjD S LUD domain
PGIHDHAF_01976 1.5e-36 UW LPXTG-motif cell wall anchor domain protein
PGIHDHAF_01978 3.4e-44 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
PGIHDHAF_01979 2.7e-25 yitW S Iron-sulfur cluster assembly protein
PGIHDHAF_01980 7.1e-92 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PGIHDHAF_01981 4.8e-64 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PGIHDHAF_01984 1.7e-98 L hmm pf00665
PGIHDHAF_01985 9.4e-87 L Helix-turn-helix domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)