ORF_ID e_value Gene_name EC_number CAZy COGs Description
JEDFLAMM_00001 3.4e-17 dnaK O Heat shock 70 kDa protein
JEDFLAMM_00002 3.3e-37 yedI S Protein of unknown function (DUF808)
JEDFLAMM_00003 2.5e-25 Q the current gene model (or a revised gene model) may contain a frame shift
JEDFLAMM_00004 1.9e-116 gltJ P ABC transporter (Permease
JEDFLAMM_00005 2.9e-111 tcyB_2 P ABC transporter (permease)
JEDFLAMM_00007 3.4e-28 2.4.1.21 GT5 M Right handed beta helix region
JEDFLAMM_00008 7.6e-134 S double-stranded DNA endodeoxyribonuclease activity
JEDFLAMM_00009 4.3e-305 hsdM 2.1.1.72 V type I restriction-modification system
JEDFLAMM_00010 2.1e-45 S Protein conserved in bacteria
JEDFLAMM_00011 8.3e-28 S Protein conserved in bacteria
JEDFLAMM_00012 0.0 S KAP family P-loop domain
JEDFLAMM_00013 1.4e-77 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
JEDFLAMM_00014 3.2e-94
JEDFLAMM_00015 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
JEDFLAMM_00017 2.3e-131 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JEDFLAMM_00018 2.5e-206 MA20_36090 S Protein of unknown function (DUF2974)
JEDFLAMM_00019 1.3e-111 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JEDFLAMM_00020 4.9e-159 5.2.1.8 G hydrolase
JEDFLAMM_00021 1.9e-25 P Hemerythrin HHE cation binding domain protein
JEDFLAMM_00022 3.5e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
JEDFLAMM_00023 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JEDFLAMM_00024 1.6e-114 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
JEDFLAMM_00026 2e-174 S hydrolase
JEDFLAMM_00027 8.4e-23
JEDFLAMM_00028 5.5e-141 M LysM domain
JEDFLAMM_00029 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JEDFLAMM_00030 2.8e-35
JEDFLAMM_00032 3.3e-236 S Domain of unknown function DUF87
JEDFLAMM_00033 1.3e-201 S SIR2-like domain
JEDFLAMM_00034 1.8e-225 mutH L DNA mismatch repair enzyme MutH
JEDFLAMM_00035 5.4e-210 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
JEDFLAMM_00036 9.6e-12
JEDFLAMM_00037 8.1e-233 mntH P H( )-stimulated, divalent metal cation uptake system
JEDFLAMM_00038 1.1e-33 XK27_12190 S protein conserved in bacteria
JEDFLAMM_00040 1.1e-87 bioY S biotin synthase
JEDFLAMM_00041 1.9e-250 yegQ O Peptidase U32
JEDFLAMM_00042 6.8e-178 yegQ O Peptidase U32
JEDFLAMM_00044 3e-67 ytxH S General stress protein
JEDFLAMM_00045 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JEDFLAMM_00046 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JEDFLAMM_00047 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JEDFLAMM_00048 2.2e-41 pspC KT PspC domain
JEDFLAMM_00049 2.1e-81 ydcK S Belongs to the SprT family
JEDFLAMM_00050 0.0 yhgF K Transcriptional accessory protein
JEDFLAMM_00052 7.1e-156 XK27_03015 S permease
JEDFLAMM_00053 1.7e-148 ycgQ S TIGR03943 family
JEDFLAMM_00054 1.6e-286 sulP P Sulfate permease and related transporters (MFS superfamily)
JEDFLAMM_00055 1.4e-102
JEDFLAMM_00056 4.2e-118 estA E GDSL-like Lipase/Acylhydrolase
JEDFLAMM_00057 3.4e-93 S CAAX protease self-immunity
JEDFLAMM_00058 1.2e-52
JEDFLAMM_00060 5.7e-64 yqeB S Pyrimidine dimer DNA glycosylase
JEDFLAMM_00061 7.1e-60 S Protein of unknown function (DUF1722)
JEDFLAMM_00062 8.4e-19 S Bacterial lipoprotein
JEDFLAMM_00063 1.5e-10
JEDFLAMM_00064 7.3e-122 S CAAX protease self-immunity
JEDFLAMM_00065 1.7e-48
JEDFLAMM_00066 2.5e-61 K TetR family transcriptional regulator
JEDFLAMM_00067 3.6e-84 Q Methyltransferase domain
JEDFLAMM_00068 9.4e-143 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JEDFLAMM_00069 7.8e-175 acoB C dehydrogenase E1 component
JEDFLAMM_00070 2e-165 acoA C Acetoin dehydrogenase E1 component subunit alpha
JEDFLAMM_00071 5.6e-173 pdhD 1.8.1.4 C Dehydrogenase
JEDFLAMM_00072 2.9e-09 S CsbD-like
JEDFLAMM_00073 2.1e-30 S Membrane
JEDFLAMM_00074 2.1e-172 S Domain of unknown function (DUF389)
JEDFLAMM_00075 1.3e-157 yegS 2.7.1.107 I Diacylglycerol kinase
JEDFLAMM_00076 3.8e-125 ybbA S Putative esterase
JEDFLAMM_00077 4.7e-172 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
JEDFLAMM_00078 3.7e-134 fecE 3.6.3.34 HP ABC transporter
JEDFLAMM_00079 2.3e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JEDFLAMM_00080 6.6e-123 V CAAX protease self-immunity
JEDFLAMM_00081 5.8e-152 S Domain of unknown function (DUF4300)
JEDFLAMM_00082 3.2e-21 S Domain of unknown function (DUF4767)
JEDFLAMM_00084 1.3e-108 cutC P Participates in the control of copper homeostasis
JEDFLAMM_00085 8.9e-129 S CAAX amino terminal protease family
JEDFLAMM_00086 9.5e-98 ypgQ F HD superfamily hydrolase
JEDFLAMM_00087 5.2e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
JEDFLAMM_00088 2.6e-152 yitS S EDD domain protein, DegV family
JEDFLAMM_00089 2.5e-201 yeaN P transporter
JEDFLAMM_00090 9.3e-130 S Domain of unknown function (DUF4336)
JEDFLAMM_00091 3.8e-134 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JEDFLAMM_00092 2.8e-44 K Transcriptional regulator
JEDFLAMM_00093 3.3e-30 S Protein of unknown function (DUF1648)
JEDFLAMM_00094 2.7e-251 6.1.1.6 S Psort location CytoplasmicMembrane, score
JEDFLAMM_00095 3.2e-127 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
JEDFLAMM_00096 2.4e-102 K Transcriptional regulator
JEDFLAMM_00097 3.6e-97
JEDFLAMM_00098 3.6e-91 K Acetyltransferase (GNAT) domain
JEDFLAMM_00099 1.9e-150 tetD K AraC family transcriptional regulator
JEDFLAMM_00100 1.1e-68 E cog cog0346
JEDFLAMM_00101 4e-53 K TfoX N-terminal domain
JEDFLAMM_00102 1.8e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JEDFLAMM_00103 2e-97 mip S hydroperoxide reductase activity
JEDFLAMM_00104 2.5e-176 I acyl-CoA dehydrogenase
JEDFLAMM_00105 3e-93 ydiA P C4-dicarboxylate transporter malic acid transport
JEDFLAMM_00106 1.1e-240 msrR K Transcriptional regulator
JEDFLAMM_00107 5.1e-153 pheA 4.2.1.51 E Prephenate dehydratase
JEDFLAMM_00108 2.7e-77 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JEDFLAMM_00109 6.4e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JEDFLAMM_00110 6.5e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JEDFLAMM_00111 9.4e-53 yheA S Belongs to the UPF0342 family
JEDFLAMM_00112 7.7e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JEDFLAMM_00113 2.9e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JEDFLAMM_00114 5e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JEDFLAMM_00115 3.5e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JEDFLAMM_00116 5.4e-116 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JEDFLAMM_00117 6.4e-218 ywbD 2.1.1.191 J Methyltransferase
JEDFLAMM_00118 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JEDFLAMM_00119 1.2e-25 WQ51_00785
JEDFLAMM_00120 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JEDFLAMM_00121 3.9e-78 yueI S Protein of unknown function (DUF1694)
JEDFLAMM_00122 4e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JEDFLAMM_00123 2.9e-201 yyaQ S YjbR
JEDFLAMM_00124 3.2e-181 ccpA K Catabolite control protein A
JEDFLAMM_00125 1.1e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
JEDFLAMM_00126 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
JEDFLAMM_00127 1.4e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JEDFLAMM_00128 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JEDFLAMM_00129 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JEDFLAMM_00130 2e-33 secG U Preprotein translocase subunit SecG
JEDFLAMM_00131 3.2e-220 mdtG EGP Major facilitator Superfamily
JEDFLAMM_00132 2.4e-99 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JEDFLAMM_00133 1.1e-147 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JEDFLAMM_00134 2.2e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JEDFLAMM_00135 9.8e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JEDFLAMM_00136 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JEDFLAMM_00137 3.5e-149 licT K antiterminator
JEDFLAMM_00138 1.7e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JEDFLAMM_00139 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
JEDFLAMM_00140 9.5e-147 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JEDFLAMM_00141 6.9e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JEDFLAMM_00142 3.5e-151 I Alpha/beta hydrolase family
JEDFLAMM_00143 3.3e-07
JEDFLAMM_00144 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
JEDFLAMM_00145 1.6e-77 feoA P FeoA domain protein
JEDFLAMM_00146 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
JEDFLAMM_00147 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
JEDFLAMM_00148 1e-34 ykuJ S protein conserved in bacteria
JEDFLAMM_00149 4.5e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JEDFLAMM_00150 0.0 clpE O Belongs to the ClpA ClpB family
JEDFLAMM_00151 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JEDFLAMM_00152 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
JEDFLAMM_00153 6.2e-174 S oxidoreductase
JEDFLAMM_00154 1.7e-229 murN 2.3.2.16 V FemAB family
JEDFLAMM_00155 1.1e-116 M Pfam SNARE associated Golgi protein
JEDFLAMM_00156 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
JEDFLAMM_00159 7.1e-204 rpsA 1.17.7.4 J ribosomal protein S1
JEDFLAMM_00162 4.8e-16 S Protein of unknown function (DUF2969)
JEDFLAMM_00163 9.1e-200 ilvE 2.6.1.42 E Aminotransferase
JEDFLAMM_00164 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JEDFLAMM_00165 4.2e-147 aadK G adenylyltransferase
JEDFLAMM_00166 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JEDFLAMM_00167 1.1e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JEDFLAMM_00168 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
JEDFLAMM_00169 2.2e-30 S Domain of unknown function (DUF1912)
JEDFLAMM_00170 8.8e-173 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
JEDFLAMM_00171 5.8e-250 mmuP E amino acid
JEDFLAMM_00172 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
JEDFLAMM_00173 4.4e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JEDFLAMM_00174 9.7e-22
JEDFLAMM_00175 5.8e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JEDFLAMM_00176 3.8e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JEDFLAMM_00177 5.3e-212 mvaS 2.3.3.10 I synthase
JEDFLAMM_00178 2.3e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
JEDFLAMM_00179 3e-78 K hmm pf08876
JEDFLAMM_00180 5.2e-119 yqfA K protein, Hemolysin III
JEDFLAMM_00181 4.1e-29 pspC KT PspC domain protein
JEDFLAMM_00182 2.5e-200 S Protein of unknown function (DUF3114)
JEDFLAMM_00183 2e-161 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JEDFLAMM_00184 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JEDFLAMM_00185 9.9e-07
JEDFLAMM_00186 8.3e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
JEDFLAMM_00187 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
JEDFLAMM_00188 0.0 U protein secretion
JEDFLAMM_00189 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JEDFLAMM_00190 4.6e-23
JEDFLAMM_00191 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
JEDFLAMM_00192 1.7e-249 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JEDFLAMM_00193 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
JEDFLAMM_00194 7.3e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JEDFLAMM_00195 3.1e-168 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
JEDFLAMM_00196 2.9e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
JEDFLAMM_00197 6.7e-143 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
JEDFLAMM_00198 1.2e-170 1.8.5.7 O Glutathione S-transferase, C-terminal domain
JEDFLAMM_00199 4.7e-150 1.8.5.7 O Glutathione S-transferase
JEDFLAMM_00201 2.8e-58 K Acetyltransferase (GNAT) domain
JEDFLAMM_00202 1.4e-97 ET Bacterial extracellular solute-binding proteins, family 3
JEDFLAMM_00204 1.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JEDFLAMM_00205 2.8e-140 E Alpha beta hydrolase
JEDFLAMM_00207 7.5e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
JEDFLAMM_00208 3.6e-213 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JEDFLAMM_00209 3.9e-125 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JEDFLAMM_00210 3.9e-114 S VIT family
JEDFLAMM_00211 2.9e-134 deoD_1 2.4.2.3 F Phosphorylase superfamily
JEDFLAMM_00212 1.2e-24
JEDFLAMM_00213 1.6e-28 XK27_00085 K Transcriptional
JEDFLAMM_00214 2e-196 yceA S Belongs to the UPF0176 family
JEDFLAMM_00215 8e-123 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JEDFLAMM_00216 1.1e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JEDFLAMM_00217 0.0 lmrA V abc transporter atp-binding protein
JEDFLAMM_00218 0.0 mdlB V abc transporter atp-binding protein
JEDFLAMM_00219 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JEDFLAMM_00220 1.1e-76 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JEDFLAMM_00221 3.5e-211 V permease protein
JEDFLAMM_00222 7.5e-121 macB V ABC transporter, ATP-binding protein
JEDFLAMM_00223 1.4e-181 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JEDFLAMM_00224 1.8e-128 2.1.1.223 S Putative SAM-dependent methyltransferase
JEDFLAMM_00225 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
JEDFLAMM_00226 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
JEDFLAMM_00227 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JEDFLAMM_00228 8.1e-222 pyrP F uracil Permease
JEDFLAMM_00229 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JEDFLAMM_00230 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JEDFLAMM_00231 4.4e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JEDFLAMM_00232 4.7e-168 fhuR K transcriptional regulator (lysR family)
JEDFLAMM_00234 1e-43
JEDFLAMM_00235 6e-66 K Helix-turn-helix
JEDFLAMM_00239 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JEDFLAMM_00240 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JEDFLAMM_00241 8.3e-10 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JEDFLAMM_00242 6e-255 cycA E permease
JEDFLAMM_00243 1.7e-38 ynzC S UPF0291 protein
JEDFLAMM_00244 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JEDFLAMM_00245 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JEDFLAMM_00246 7.3e-220 S membrane
JEDFLAMM_00247 8.6e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JEDFLAMM_00248 2.2e-293 nptA P COG1283 Na phosphate symporter
JEDFLAMM_00249 6.8e-113 3.4.17.14, 3.5.1.28 NU amidase activity
JEDFLAMM_00250 8.9e-82 S Bacterial inner membrane protein
JEDFLAMM_00251 1.9e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
JEDFLAMM_00252 1.2e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
JEDFLAMM_00253 1.9e-53 glnB K Belongs to the P(II) protein family
JEDFLAMM_00254 2.8e-227 amt P Ammonium Transporter
JEDFLAMM_00255 2.8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JEDFLAMM_00256 3.6e-54 yabA L Involved in initiation control of chromosome replication
JEDFLAMM_00257 3.7e-132 yaaT S stage 0 sporulation protein
JEDFLAMM_00258 1.3e-159 holB 2.7.7.7 L dna polymerase iii
JEDFLAMM_00259 2.3e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JEDFLAMM_00261 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JEDFLAMM_00262 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JEDFLAMM_00263 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JEDFLAMM_00264 9.2e-218 ftsW D Belongs to the SEDS family
JEDFLAMM_00265 1.3e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JEDFLAMM_00266 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JEDFLAMM_00267 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JEDFLAMM_00268 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JEDFLAMM_00269 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JEDFLAMM_00270 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JEDFLAMM_00271 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
JEDFLAMM_00272 8.3e-17 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JEDFLAMM_00273 1.1e-31
JEDFLAMM_00274 9.9e-177 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
JEDFLAMM_00275 1.6e-216 ddeI 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
JEDFLAMM_00276 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JEDFLAMM_00278 7.4e-19
JEDFLAMM_00279 7.9e-97 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
JEDFLAMM_00280 1.4e-101 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JEDFLAMM_00283 3e-14 coiA 3.6.4.12 S Competence protein
JEDFLAMM_00284 2.2e-15 T peptidase
JEDFLAMM_00285 2.6e-150 rarD S Transporter
JEDFLAMM_00286 9.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JEDFLAMM_00287 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
JEDFLAMM_00288 7.7e-131 yxkH G deacetylase
JEDFLAMM_00289 9.4e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JEDFLAMM_00290 1.1e-127 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
JEDFLAMM_00291 1.3e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JEDFLAMM_00292 2.2e-185 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JEDFLAMM_00293 2.7e-224 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
JEDFLAMM_00294 2.5e-141 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JEDFLAMM_00295 3e-201 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JEDFLAMM_00296 1.4e-57 yaaA S S4 domain protein YaaA
JEDFLAMM_00297 6.7e-229 ymfF S Peptidase M16
JEDFLAMM_00298 1.4e-237 ymfH S Peptidase M16
JEDFLAMM_00299 1.2e-131 S sequence-specific DNA binding
JEDFLAMM_00300 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JEDFLAMM_00301 1.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JEDFLAMM_00302 8.9e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JEDFLAMM_00303 1.7e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JEDFLAMM_00304 2e-71 lytE M LysM domain protein
JEDFLAMM_00305 2e-65 isaA GH23 M Immunodominant staphylococcal antigen A
JEDFLAMM_00306 3.7e-307 S Bacterial membrane protein, YfhO
JEDFLAMM_00307 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JEDFLAMM_00308 1e-97 yvbG U UPF0056 membrane protein
JEDFLAMM_00309 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JEDFLAMM_00310 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JEDFLAMM_00311 2.2e-73 rplI J binds to the 23S rRNA
JEDFLAMM_00312 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JEDFLAMM_00313 1.8e-47 veg S Biofilm formation stimulator VEG
JEDFLAMM_00314 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JEDFLAMM_00315 1.9e-10
JEDFLAMM_00316 1.7e-52 ypaA M Membrane
JEDFLAMM_00317 9.9e-97 XK27_06935 K transcriptional regulator
JEDFLAMM_00318 8.1e-159 XK27_06930 V domain protein
JEDFLAMM_00319 9.4e-102 S Putative adhesin
JEDFLAMM_00320 6.8e-59 XK27_06920 S Protein of unknown function (DUF1700)
JEDFLAMM_00321 5.5e-50 K transcriptional regulator, PadR family
JEDFLAMM_00322 4.5e-114 nudL L hydrolase
JEDFLAMM_00325 3.3e-07
JEDFLAMM_00326 5.1e-27 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JEDFLAMM_00327 0.0
JEDFLAMM_00328 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
JEDFLAMM_00329 3.4e-149 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
JEDFLAMM_00331 2.9e-161 T Diguanylate cyclase
JEDFLAMM_00332 4.1e-34 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
JEDFLAMM_00333 1.7e-60 fruR K transcriptional
JEDFLAMM_00334 9.8e-132 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
JEDFLAMM_00335 4.2e-37 L Transposase
JEDFLAMM_00336 3e-62 tnp* 1.1.1.193 L An automated process has identified a potential problem with this gene model
JEDFLAMM_00337 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JEDFLAMM_00338 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JEDFLAMM_00339 1.5e-219 metE 2.1.1.14 E Methionine synthase
JEDFLAMM_00340 1.4e-185 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JEDFLAMM_00341 6.2e-32 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JEDFLAMM_00342 5e-240 hisS 6.1.1.21 J histidyl-tRNA synthetase
JEDFLAMM_00344 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JEDFLAMM_00345 9.3e-167 XK27_01785 S cog cog1284
JEDFLAMM_00346 4e-122 yaaA S Belongs to the UPF0246 family
JEDFLAMM_00347 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JEDFLAMM_00348 2.4e-89 XK27_10930 K acetyltransferase
JEDFLAMM_00349 7.5e-14
JEDFLAMM_00350 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
JEDFLAMM_00351 4.4e-289 ccs S the current gene model (or a revised gene model) may contain a frame shift
JEDFLAMM_00352 2.1e-43 yrzB S Belongs to the UPF0473 family
JEDFLAMM_00353 2.3e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JEDFLAMM_00354 6.3e-44 yrzL S Belongs to the UPF0297 family
JEDFLAMM_00355 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JEDFLAMM_00356 3.7e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
JEDFLAMM_00358 7.7e-216 int L Belongs to the 'phage' integrase family
JEDFLAMM_00359 1.9e-18 S Domain of unknown function (DUF3173)
JEDFLAMM_00360 2e-156 L Replication initiation factor
JEDFLAMM_00361 3.8e-90 K Cro/C1-type HTH DNA-binding domain
JEDFLAMM_00362 1.1e-173 yeiH S membrane
JEDFLAMM_00364 3.1e-92 adk 2.7.4.3 F topology modulation protein
JEDFLAMM_00365 7.8e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JEDFLAMM_00366 1.7e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JEDFLAMM_00367 9.7e-36 XK27_09805 S MORN repeat protein
JEDFLAMM_00368 0.0 XK27_09800 I Acyltransferase
JEDFLAMM_00369 1.8e-184 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JEDFLAMM_00370 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
JEDFLAMM_00371 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JEDFLAMM_00372 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
JEDFLAMM_00373 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JEDFLAMM_00374 1.5e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JEDFLAMM_00375 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JEDFLAMM_00376 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JEDFLAMM_00377 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JEDFLAMM_00378 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JEDFLAMM_00379 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
JEDFLAMM_00380 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JEDFLAMM_00381 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JEDFLAMM_00382 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JEDFLAMM_00383 3.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JEDFLAMM_00384 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JEDFLAMM_00385 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JEDFLAMM_00386 8.7e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JEDFLAMM_00387 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JEDFLAMM_00388 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JEDFLAMM_00389 1.9e-23 rpmD J ribosomal protein l30
JEDFLAMM_00390 5.7e-58 rplO J binds to the 23S rRNA
JEDFLAMM_00391 1.2e-228 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JEDFLAMM_00392 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JEDFLAMM_00393 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JEDFLAMM_00394 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JEDFLAMM_00395 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JEDFLAMM_00396 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JEDFLAMM_00397 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JEDFLAMM_00398 4.4e-62 rplQ J ribosomal protein l17
JEDFLAMM_00399 4e-245 6.3.2.2 H gamma-glutamylcysteine synthetase
JEDFLAMM_00401 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
JEDFLAMM_00403 1.3e-94 ywlG S Belongs to the UPF0340 family
JEDFLAMM_00404 7.9e-126 treR K trehalose operon
JEDFLAMM_00405 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JEDFLAMM_00406 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JEDFLAMM_00407 0.0 pepO 3.4.24.71 O Peptidase family M13
JEDFLAMM_00408 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JEDFLAMM_00411 1.3e-276 thrC 4.2.3.1 E Threonine synthase
JEDFLAMM_00412 5.6e-223 norN V Mate efflux family protein
JEDFLAMM_00413 1.4e-57 asp S cog cog1302
JEDFLAMM_00414 2.3e-301 yloV S kinase related to dihydroxyacetone kinase
JEDFLAMM_00415 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JEDFLAMM_00416 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
JEDFLAMM_00417 5.5e-75 ilvN 2.2.1.6 E Acetolactate synthase
JEDFLAMM_00418 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JEDFLAMM_00419 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JEDFLAMM_00420 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JEDFLAMM_00421 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JEDFLAMM_00422 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JEDFLAMM_00423 5e-68 S cog cog4699
JEDFLAMM_00424 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JEDFLAMM_00425 1.1e-142 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JEDFLAMM_00426 2.2e-43 comGC U Required for transformation and DNA binding
JEDFLAMM_00427 8.4e-70 cglD NU Competence protein
JEDFLAMM_00428 5.3e-15 NU Type II secretory pathway pseudopilin
JEDFLAMM_00429 5.8e-71 comGF U Competence protein ComGF
JEDFLAMM_00430 1.2e-12 comGF U Putative Competence protein ComGF
JEDFLAMM_00431 5e-176 ytxK 2.1.1.72 L DNA methylase
JEDFLAMM_00432 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JEDFLAMM_00433 8.8e-27 lanR K sequence-specific DNA binding
JEDFLAMM_00434 2.6e-107 V CAAX protease self-immunity
JEDFLAMM_00436 9.6e-102 S CAAX amino terminal protease family protein
JEDFLAMM_00437 5.7e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JEDFLAMM_00438 4.8e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JEDFLAMM_00439 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
JEDFLAMM_00440 9.4e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JEDFLAMM_00441 2.6e-09 S NTF2 fold immunity protein
JEDFLAMM_00442 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JEDFLAMM_00443 1.9e-113 S CAAX protease self-immunity
JEDFLAMM_00444 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JEDFLAMM_00445 6.6e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JEDFLAMM_00449 5e-156 rrmA 2.1.1.187 Q methyltransferase
JEDFLAMM_00450 1.5e-135 S HAD hydrolase, family IA, variant
JEDFLAMM_00451 1.5e-57 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JEDFLAMM_00452 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JEDFLAMM_00453 7e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JEDFLAMM_00454 1.3e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
JEDFLAMM_00455 1.9e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JEDFLAMM_00456 5.3e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JEDFLAMM_00457 7.9e-97 XK27_08585 S Psort location CytoplasmicMembrane, score
JEDFLAMM_00458 2.1e-140 fnt P Formate nitrite transporter
JEDFLAMM_00459 7.9e-230 XK27_09615 C reductase
JEDFLAMM_00460 1.8e-107 XK27_09620 S FMN reductase (NADPH) activity
JEDFLAMM_00461 2.7e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
JEDFLAMM_00462 9.3e-76 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
JEDFLAMM_00463 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JEDFLAMM_00464 7e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
JEDFLAMM_00465 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
JEDFLAMM_00466 1.2e-50 S Protein of unknown function (DUF3397)
JEDFLAMM_00467 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JEDFLAMM_00468 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JEDFLAMM_00469 0.0 amiA E ABC transporter, substrate-binding protein, family 5
JEDFLAMM_00470 2.3e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JEDFLAMM_00471 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
JEDFLAMM_00472 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
JEDFLAMM_00473 2.4e-210 hpk9 2.7.13.3 T protein histidine kinase activity
JEDFLAMM_00474 3e-224 fasC 2.7.13.3 T protein histidine kinase activity
JEDFLAMM_00475 7.2e-130 fasA KT Response regulator of the LytR AlgR family
JEDFLAMM_00476 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JEDFLAMM_00477 3.5e-263 argH 4.3.2.1 E Argininosuccinate lyase
JEDFLAMM_00478 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JEDFLAMM_00479 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JEDFLAMM_00480 1.1e-173 jag S RNA-binding protein
JEDFLAMM_00481 3e-102 K Transcriptional regulator
JEDFLAMM_00482 3.4e-100 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
JEDFLAMM_00483 3.4e-14 rpmH J Ribosomal protein L34
JEDFLAMM_00484 1.8e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JEDFLAMM_00485 3.5e-39 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JEDFLAMM_00486 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JEDFLAMM_00487 6.5e-131 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JEDFLAMM_00488 9.1e-178 prmA J Ribosomal protein L11 methyltransferase
JEDFLAMM_00489 4.9e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
JEDFLAMM_00490 7.9e-82 XK27_03960 S Protein of unknown function (DUF3013)
JEDFLAMM_00491 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JEDFLAMM_00492 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JEDFLAMM_00493 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JEDFLAMM_00494 3.1e-139 ykuT M mechanosensitive ion channel
JEDFLAMM_00495 1.9e-86 sigH K DNA-templated transcription, initiation
JEDFLAMM_00497 5.4e-229 2.7.13.3 T GHKL domain
JEDFLAMM_00498 3.1e-133 agrA KT phosphorelay signal transduction system
JEDFLAMM_00499 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JEDFLAMM_00501 7.7e-09
JEDFLAMM_00502 1.6e-166 K sequence-specific DNA binding
JEDFLAMM_00503 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JEDFLAMM_00504 7.1e-86 yxjI S LURP-one-related
JEDFLAMM_00505 5.1e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
JEDFLAMM_00506 3.9e-119 yrrM 2.1.1.104 S O-Methyltransferase
JEDFLAMM_00507 9.4e-212 oxlT P COG0477 Permeases of the major facilitator superfamily
JEDFLAMM_00508 0.0 pepF E oligoendopeptidase F
JEDFLAMM_00509 1.5e-164 coiA 3.6.4.12 S Competence protein
JEDFLAMM_00510 3.6e-274 S Glucan-binding protein C
JEDFLAMM_00511 1e-107 S CAAX amino terminal protease family protein
JEDFLAMM_00512 4.7e-168 K transcriptional regulator (lysR family)
JEDFLAMM_00513 3.4e-160 S reductase
JEDFLAMM_00514 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JEDFLAMM_00518 1.3e-188 phoH T phosphate starvation-inducible protein PhoH
JEDFLAMM_00519 6.2e-126 sip M LysM domain protein
JEDFLAMM_00520 3.7e-34 yozE S Belongs to the UPF0346 family
JEDFLAMM_00521 2.5e-158 cvfB S Protein conserved in bacteria
JEDFLAMM_00522 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JEDFLAMM_00523 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JEDFLAMM_00524 4.1e-215 sptS 2.7.13.3 T Histidine kinase
JEDFLAMM_00525 8.3e-117 T response regulator
JEDFLAMM_00526 9.7e-112 2.7.6.5 S Region found in RelA / SpoT proteins
JEDFLAMM_00527 6.7e-113 K Acetyltransferase (GNAT) family
JEDFLAMM_00528 0.0 lmrA2 V abc transporter atp-binding protein
JEDFLAMM_00529 0.0 lmrA1 V abc transporter atp-binding protein
JEDFLAMM_00530 3.3e-74 K DNA-binding transcription factor activity
JEDFLAMM_00531 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
JEDFLAMM_00532 5.4e-271 S Psort location CytoplasmicMembrane, score
JEDFLAMM_00533 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
JEDFLAMM_00534 2.7e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
JEDFLAMM_00535 2.8e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
JEDFLAMM_00536 1.3e-26 U response to pH
JEDFLAMM_00537 0.0 yfmR S abc transporter atp-binding protein
JEDFLAMM_00538 1.5e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JEDFLAMM_00539 4.3e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JEDFLAMM_00540 2.5e-147 XK27_08360 S EDD domain protein, DegV family
JEDFLAMM_00541 5e-63 WQ51_03320 S cog cog4835
JEDFLAMM_00542 4.7e-131 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JEDFLAMM_00543 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JEDFLAMM_00544 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JEDFLAMM_00545 1.3e-93 2.3.1.128 K acetyltransferase
JEDFLAMM_00546 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
JEDFLAMM_00547 3.5e-293 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
JEDFLAMM_00548 6.3e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JEDFLAMM_00549 7.5e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
JEDFLAMM_00551 1.1e-226 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JEDFLAMM_00552 2.1e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JEDFLAMM_00553 0.0 fruA 2.7.1.202 G phosphotransferase system
JEDFLAMM_00554 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
JEDFLAMM_00555 5.2e-112 fruR K transcriptional
JEDFLAMM_00556 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
JEDFLAMM_00557 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JEDFLAMM_00558 3.9e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JEDFLAMM_00559 1.1e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JEDFLAMM_00560 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JEDFLAMM_00561 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JEDFLAMM_00562 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JEDFLAMM_00563 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JEDFLAMM_00564 1.8e-125 IQ reductase
JEDFLAMM_00565 7.5e-161 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
JEDFLAMM_00566 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
JEDFLAMM_00567 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JEDFLAMM_00568 1.1e-162 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JEDFLAMM_00569 5.2e-72 marR K Transcriptional regulator, MarR family
JEDFLAMM_00570 3.1e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
JEDFLAMM_00571 2.2e-111 S HAD hydrolase, family IA, variant 3
JEDFLAMM_00572 1e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
JEDFLAMM_00573 2e-71 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JEDFLAMM_00574 5.6e-28 S Putative phosphatase (DUF442)
JEDFLAMM_00575 9.8e-70 L Transposase DDE domain
JEDFLAMM_00576 8.2e-87 L Transposase DDE domain
JEDFLAMM_00579 1.4e-234 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
JEDFLAMM_00580 1.5e-71 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JEDFLAMM_00581 1.1e-14 L Initiator Replication protein
JEDFLAMM_00582 6.9e-215 L Transposase IS116 IS110 IS902
JEDFLAMM_00583 1.4e-50 L Transposase DDE domain
JEDFLAMM_00587 2.6e-10
JEDFLAMM_00590 1.9e-07
JEDFLAMM_00595 4.2e-198 L Belongs to the 'phage' integrase family
JEDFLAMM_00596 3.5e-28 S Domain of unknown function (DUF3173)
JEDFLAMM_00597 3.4e-67
JEDFLAMM_00598 7e-228 L Replication initiation factor
JEDFLAMM_00599 8.5e-76
JEDFLAMM_00600 3.9e-78 K transcriptional
JEDFLAMM_00601 1.1e-44
JEDFLAMM_00603 3.6e-159
JEDFLAMM_00604 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JEDFLAMM_00605 2.5e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JEDFLAMM_00606 5.5e-36 XK27_02060 S Transglycosylase associated protein
JEDFLAMM_00607 2.6e-71 badR K Transcriptional regulator, marr family
JEDFLAMM_00608 4.7e-94 S reductase
JEDFLAMM_00610 3.5e-288 ahpF O alkyl hydroperoxide reductase
JEDFLAMM_00611 2.4e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
JEDFLAMM_00612 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
JEDFLAMM_00613 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JEDFLAMM_00614 1.6e-82 S Putative small multi-drug export protein
JEDFLAMM_00615 2e-74 ctsR K Belongs to the CtsR family
JEDFLAMM_00616 0.0 clpC O Belongs to the ClpA ClpB family
JEDFLAMM_00617 2.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JEDFLAMM_00618 2.1e-222 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JEDFLAMM_00619 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JEDFLAMM_00620 3.6e-140 S SseB protein N-terminal domain
JEDFLAMM_00621 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
JEDFLAMM_00623 2.4e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JEDFLAMM_00624 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JEDFLAMM_00626 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JEDFLAMM_00627 7.8e-91 yacP S RNA-binding protein containing a PIN domain
JEDFLAMM_00628 2.2e-151 degV S DegV family
JEDFLAMM_00630 5.1e-22 K Transcriptional
JEDFLAMM_00631 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JEDFLAMM_00632 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
JEDFLAMM_00633 3.4e-18
JEDFLAMM_00634 1.5e-29 K Helix-turn-helix domain
JEDFLAMM_00636 4.6e-149 srtB 3.4.22.70 S Sortase family
JEDFLAMM_00637 1.3e-232 capA M Bacterial capsule synthesis protein
JEDFLAMM_00638 6.1e-39 gcvR T UPF0237 protein
JEDFLAMM_00639 3.9e-243 XK27_08635 S UPF0210 protein
JEDFLAMM_00640 1.4e-130 ais G Phosphoglycerate mutase
JEDFLAMM_00641 5.3e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JEDFLAMM_00642 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
JEDFLAMM_00643 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JEDFLAMM_00644 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JEDFLAMM_00645 6e-303 dnaK O Heat shock 70 kDa protein
JEDFLAMM_00646 2e-104 thiJ-2 3.5.1.124 S DJ-1/PfpI family
JEDFLAMM_00647 1.2e-192 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JEDFLAMM_00648 2e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JEDFLAMM_00649 5.8e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
JEDFLAMM_00650 1.7e-79 hmpT S cog cog4720
JEDFLAMM_00651 1.6e-232 K Replication initiation factor
JEDFLAMM_00652 1.9e-30 S Psort location CytoplasmicMembrane, score
JEDFLAMM_00653 7.5e-91 S Antirestriction protein (ArdA)
JEDFLAMM_00654 3.8e-90 S TcpE family
JEDFLAMM_00655 0.0 S AAA-like domain
JEDFLAMM_00656 0.0 S the current gene model (or a revised gene model) may contain a frame shift
JEDFLAMM_00657 2.2e-190 yddH M NlpC p60 family protein
JEDFLAMM_00658 7.4e-169 S Conjugative transposon protein TcpC
JEDFLAMM_00659 0.0 tetP J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JEDFLAMM_00660 1.6e-134 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
JEDFLAMM_00661 1.6e-16
JEDFLAMM_00662 5.6e-95 L Resolvase, N terminal domain
JEDFLAMM_00663 0.0 L Transposase and inactivated derivatives, TnpA family
JEDFLAMM_00664 3.9e-37 K Helix-turn-helix domain
JEDFLAMM_00665 1.1e-71 phyR K Sigma-70, region 4
JEDFLAMM_00666 9.3e-36 S Helix-turn-helix domain
JEDFLAMM_00667 1.8e-30 xis S Excisionase from transposon Tn916
JEDFLAMM_00668 6.3e-232 L DNA binding domain of tn916 integrase
JEDFLAMM_00669 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JEDFLAMM_00670 2.8e-110 yhfC S Putative membrane peptidase family (DUF2324)
JEDFLAMM_00671 4.2e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
JEDFLAMM_00672 1e-14 S integral membrane protein
JEDFLAMM_00673 4.6e-191 mccF V LD-carboxypeptidase
JEDFLAMM_00674 5.3e-08 S Enterocin A Immunity
JEDFLAMM_00675 2.4e-34 S Immunity protein 41
JEDFLAMM_00676 0.0 M Putative cell wall binding repeat
JEDFLAMM_00677 3.8e-224 thrE K Psort location CytoplasmicMembrane, score
JEDFLAMM_00678 2.3e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
JEDFLAMM_00679 2.9e-94 dhaL 2.7.1.121 S Dihydroxyacetone kinase
JEDFLAMM_00680 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
JEDFLAMM_00681 5.5e-178 XK27_10475 S oxidoreductase
JEDFLAMM_00682 6.5e-196 gldA 1.1.1.6 C glycerol dehydrogenase
JEDFLAMM_00684 1.6e-282 XK27_07020 S Belongs to the UPF0371 family
JEDFLAMM_00685 1.1e-212 vex1 V Efflux ABC transporter, permease protein
JEDFLAMM_00686 1.9e-107 vex2 V abc transporter atp-binding protein
JEDFLAMM_00687 3.4e-234 vex3 V Efflux ABC transporter, permease protein
JEDFLAMM_00688 7.5e-115 K Response regulator receiver domain protein
JEDFLAMM_00689 2.2e-219 vncS 2.7.13.3 T Histidine kinase
JEDFLAMM_00690 7.4e-144 msmR K AraC family transcriptional regulator
JEDFLAMM_00691 0.0 rafA 3.2.1.22 G alpha-galactosidase
JEDFLAMM_00692 9.7e-196 msmE G Bacterial extracellular solute-binding protein
JEDFLAMM_00693 2.7e-144 msmF P Binding-protein-dependent transport system inner membrane component
JEDFLAMM_00694 1.3e-143 msmG P ABC-type sugar transport system, permease component
JEDFLAMM_00695 3e-188 msmX P Belongs to the ABC transporter superfamily
JEDFLAMM_00696 4.5e-97 iolC 2.7.1.4 G pfkB family carbohydrate kinase
JEDFLAMM_00697 4.3e-195 gtfA 2.4.1.329, 2.4.1.7 GH13 G Alpha amylase, catalytic domain
JEDFLAMM_00698 8.7e-306 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
JEDFLAMM_00699 3.1e-147 galR K Transcriptional regulator
JEDFLAMM_00700 1.5e-219 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JEDFLAMM_00701 5.4e-246 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
JEDFLAMM_00702 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JEDFLAMM_00703 1.3e-156 yvgN C reductase
JEDFLAMM_00704 4.8e-96 yoaK S Protein of unknown function (DUF1275)
JEDFLAMM_00705 7e-110 drgA C nitroreductase
JEDFLAMM_00706 1.8e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JEDFLAMM_00707 1.8e-153 E Alpha/beta hydrolase of unknown function (DUF915)
JEDFLAMM_00708 2.5e-77 ywnA K Transcriptional regulator
JEDFLAMM_00709 5.5e-150 1.13.11.2 S glyoxalase
JEDFLAMM_00710 2.4e-107 XK27_02070 S nitroreductase
JEDFLAMM_00711 9.4e-31
JEDFLAMM_00712 5.5e-27 XK27_07105 K transcriptional
JEDFLAMM_00714 4e-170 ydhF S Aldo keto reductase
JEDFLAMM_00715 1.3e-97 K WHG domain
JEDFLAMM_00716 6e-123 V abc transporter atp-binding protein
JEDFLAMM_00717 1.3e-202 P FtsX-like permease family
JEDFLAMM_00718 1.5e-42 S Sugar efflux transporter for intercellular exchange
JEDFLAMM_00719 5.6e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JEDFLAMM_00720 1.6e-172 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
JEDFLAMM_00721 1.8e-164 ET ABC transporter substrate-binding protein
JEDFLAMM_00722 7e-111 ytmL P ABC transporter (Permease
JEDFLAMM_00723 1.9e-113 yxeN P ABC transporter, permease protein
JEDFLAMM_00724 2.1e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
JEDFLAMM_00726 1.4e-57 M Putative cell wall binding repeat
JEDFLAMM_00727 0.0 S dextransucrase activity
JEDFLAMM_00728 6.5e-217 yfnA E amino acid
JEDFLAMM_00729 6.8e-51 XK27_01300 P Protein conserved in bacteria
JEDFLAMM_00730 1.9e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
JEDFLAMM_00731 4.1e-08 csbD K CsbD-like
JEDFLAMM_00732 1.5e-107 S Protein of unknown function (DUF421)
JEDFLAMM_00733 1.8e-59 S Protein of unknown function (DUF3290)
JEDFLAMM_00734 5.1e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
JEDFLAMM_00735 2.2e-230 brnQ E Component of the transport system for branched-chain amino acids
JEDFLAMM_00736 1.4e-129 T ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JEDFLAMM_00737 0.0 S Domain of unknown function DUF87
JEDFLAMM_00738 4.2e-32 T DNase/tRNase domain of colicin-like bacteriocin
JEDFLAMM_00739 4.8e-13
JEDFLAMM_00740 4.5e-177 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JEDFLAMM_00742 4.1e-232 norM V Multidrug efflux pump
JEDFLAMM_00743 2.9e-143 K sequence-specific DNA binding
JEDFLAMM_00744 1.3e-269 V (ABC) transporter
JEDFLAMM_00745 4.2e-223 pbuX F xanthine permease
JEDFLAMM_00746 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JEDFLAMM_00747 3.5e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JEDFLAMM_00748 6e-161 T Histidine kinase
JEDFLAMM_00749 6.4e-134 macB2 V ABC transporter, ATP-binding protein
JEDFLAMM_00750 0.0 V ABC transporter (permease)
JEDFLAMM_00751 6.1e-93 XK27_05000 S metal cluster binding
JEDFLAMM_00752 4.4e-30 liaI KT membrane
JEDFLAMM_00753 2.4e-15 liaI KT membrane
JEDFLAMM_00754 5.3e-156 XK27_09825 V abc transporter atp-binding protein
JEDFLAMM_00755 4.8e-118 yvfS V Transporter
JEDFLAMM_00756 2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
JEDFLAMM_00757 7.3e-164 yocS S Transporter
JEDFLAMM_00760 1.9e-158 XK27_09825 V abc transporter atp-binding protein
JEDFLAMM_00761 2.6e-132 yvfS V ABC-2 type transporter
JEDFLAMM_00762 4.5e-189 desK 2.7.13.3 T Histidine kinase
JEDFLAMM_00763 6.7e-102 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JEDFLAMM_00764 1.3e-117
JEDFLAMM_00765 4.4e-86
JEDFLAMM_00767 3.7e-22
JEDFLAMM_00768 5.3e-34
JEDFLAMM_00769 1.5e-17
JEDFLAMM_00770 8.3e-48
JEDFLAMM_00771 1.1e-79 3.4.21.89 S RDD family
JEDFLAMM_00772 3.3e-161 yjlA EG membrane
JEDFLAMM_00773 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
JEDFLAMM_00774 2.2e-146 sdaAA 4.3.1.17 E L-serine dehydratase
JEDFLAMM_00775 1.8e-119 sdaAB 4.3.1.17 E L-serine dehydratase
JEDFLAMM_00776 1.7e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
JEDFLAMM_00777 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JEDFLAMM_00778 1.5e-36 L RePlication protein
JEDFLAMM_00779 2.6e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JEDFLAMM_00780 3.5e-280 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
JEDFLAMM_00781 4.9e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JEDFLAMM_00782 6.3e-93 pat 2.3.1.183 M acetyltransferase
JEDFLAMM_00783 2.9e-290 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JEDFLAMM_00784 3.1e-121 alkD L Dna alkylation repair
JEDFLAMM_00785 6.2e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JEDFLAMM_00786 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JEDFLAMM_00787 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JEDFLAMM_00788 0.0 smc D Required for chromosome condensation and partitioning
JEDFLAMM_00789 1.1e-22 WQ51_00220 K Helix-turn-helix domain
JEDFLAMM_00790 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JEDFLAMM_00791 2.3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JEDFLAMM_00792 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JEDFLAMM_00794 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
JEDFLAMM_00795 2.2e-235 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JEDFLAMM_00797 9.4e-81 S ECF-type riboflavin transporter, S component
JEDFLAMM_00798 1.1e-134 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
JEDFLAMM_00799 3.4e-81 XK27_01265 S ECF-type riboflavin transporter, S component
JEDFLAMM_00800 2.5e-294 yfmM S abc transporter atp-binding protein
JEDFLAMM_00801 6.6e-254 noxE P NADH oxidase
JEDFLAMM_00802 9.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JEDFLAMM_00803 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JEDFLAMM_00804 3.2e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
JEDFLAMM_00805 2.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
JEDFLAMM_00806 6.4e-163 ypuA S secreted protein
JEDFLAMM_00807 1.5e-228 mntH P Mn2 and Fe2 transporters of the NRAMP family
JEDFLAMM_00808 4.4e-45 rpmE2 J 50S ribosomal protein L31
JEDFLAMM_00809 1.7e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JEDFLAMM_00810 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
JEDFLAMM_00811 1.1e-152 gst O Glutathione S-transferase
JEDFLAMM_00812 1.8e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JEDFLAMM_00813 2.6e-109 tdk 2.7.1.21 F thymidine kinase
JEDFLAMM_00814 1.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JEDFLAMM_00815 3.7e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JEDFLAMM_00816 1.6e-103 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JEDFLAMM_00817 5.1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JEDFLAMM_00818 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
JEDFLAMM_00819 1.4e-99 pvaA M lytic transglycosylase activity
JEDFLAMM_00820 4.5e-292 yfiB1 V abc transporter atp-binding protein
JEDFLAMM_00821 0.0 XK27_10035 V abc transporter atp-binding protein
JEDFLAMM_00822 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JEDFLAMM_00823 1.6e-235 dltB M Membrane protein involved in D-alanine export
JEDFLAMM_00824 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JEDFLAMM_00825 9.1e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JEDFLAMM_00826 0.0 3.6.3.8 P cation transport ATPase
JEDFLAMM_00827 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
JEDFLAMM_00829 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JEDFLAMM_00830 3.3e-166 metF 1.5.1.20 E reductase
JEDFLAMM_00831 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JEDFLAMM_00832 2.9e-91 panT S Psort location CytoplasmicMembrane, score
JEDFLAMM_00833 6.4e-94 panT S ECF transporter, substrate-specific component
JEDFLAMM_00834 3.3e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JEDFLAMM_00835 1e-114 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
JEDFLAMM_00836 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
JEDFLAMM_00837 2.5e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JEDFLAMM_00838 3.3e-240 T PhoQ Sensor
JEDFLAMM_00839 1e-29 rpsT J Binds directly to 16S ribosomal RNA
JEDFLAMM_00840 4.7e-171 coaA 2.7.1.33 F Pantothenic acid kinase
JEDFLAMM_00841 3.2e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
JEDFLAMM_00842 7.3e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
JEDFLAMM_00843 3e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JEDFLAMM_00844 7.4e-65 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JEDFLAMM_00845 3.2e-187 tcsA S membrane
JEDFLAMM_00846 1.6e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JEDFLAMM_00847 2.6e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
JEDFLAMM_00848 2e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
JEDFLAMM_00849 5.4e-118 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JEDFLAMM_00850 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JEDFLAMM_00851 1.1e-81 ypmB S Protein conserved in bacteria
JEDFLAMM_00852 3.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JEDFLAMM_00853 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JEDFLAMM_00854 1.3e-19
JEDFLAMM_00855 6.6e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
JEDFLAMM_00856 3.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JEDFLAMM_00857 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
JEDFLAMM_00858 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JEDFLAMM_00859 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
JEDFLAMM_00860 8.3e-202 D nuclear chromosome segregation
JEDFLAMM_00861 3.1e-136 yejC S cyclic nucleotide-binding protein
JEDFLAMM_00862 1.3e-162 rapZ S Displays ATPase and GTPase activities
JEDFLAMM_00863 6.9e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JEDFLAMM_00864 5.7e-161 whiA K May be required for sporulation
JEDFLAMM_00865 9.6e-277 pepD E Dipeptidase
JEDFLAMM_00866 6.1e-146 XK27_10720 D peptidase activity
JEDFLAMM_00867 1.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
JEDFLAMM_00868 3.4e-09
JEDFLAMM_00870 1.1e-168 yeiH S Membrane
JEDFLAMM_00871 6e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
JEDFLAMM_00872 2.9e-165 cpsY K Transcriptional regulator
JEDFLAMM_00873 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JEDFLAMM_00874 1.9e-58 phnA P Alkylphosphonate utilization operon protein PhnA
JEDFLAMM_00875 1.4e-105 artQ P ABC transporter (Permease
JEDFLAMM_00876 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
JEDFLAMM_00877 2.3e-156 aatB ET ABC transporter substrate-binding protein
JEDFLAMM_00878 5.7e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JEDFLAMM_00879 1.2e-45
JEDFLAMM_00880 3.6e-188 adhP 1.1.1.1 C alcohol dehydrogenase
JEDFLAMM_00881 1.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
JEDFLAMM_00882 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JEDFLAMM_00883 1e-235 vicK 2.7.13.3 T Histidine kinase
JEDFLAMM_00884 4.6e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
JEDFLAMM_00885 1e-57 S Protein of unknown function (DUF454)
JEDFLAMM_00886 7.4e-225 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
JEDFLAMM_00887 4.6e-146 yidA S hydrolases of the HAD superfamily
JEDFLAMM_00888 2.2e-146 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
JEDFLAMM_00889 5.3e-68 ywiB S Domain of unknown function (DUF1934)
JEDFLAMM_00890 0.0 pacL 3.6.3.8 P cation transport ATPase
JEDFLAMM_00891 1e-131 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
JEDFLAMM_00892 9.5e-155 yjjH S Calcineurin-like phosphoesterase
JEDFLAMM_00893 1.3e-199 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JEDFLAMM_00894 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JEDFLAMM_00895 3.2e-124 ftsE D cell division ATP-binding protein FtsE
JEDFLAMM_00896 2.1e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JEDFLAMM_00897 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
JEDFLAMM_00898 5.6e-177 yubA S permease
JEDFLAMM_00899 3.5e-222 G COG0457 FOG TPR repeat
JEDFLAMM_00900 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JEDFLAMM_00901 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JEDFLAMM_00902 1.2e-227 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JEDFLAMM_00903 8.6e-87 ebsA S Family of unknown function (DUF5322)
JEDFLAMM_00904 2.5e-17 M LysM domain
JEDFLAMM_00905 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JEDFLAMM_00906 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JEDFLAMM_00907 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JEDFLAMM_00908 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JEDFLAMM_00909 8.5e-84 XK27_03610 K Gnat family
JEDFLAMM_00910 1.6e-91 yybC
JEDFLAMM_00911 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
JEDFLAMM_00912 2.1e-271 pepV 3.5.1.18 E Dipeptidase
JEDFLAMM_00913 3.6e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
JEDFLAMM_00914 3.8e-227 V Glucan-binding protein C
JEDFLAMM_00915 2.5e-253 V Glucan-binding protein C
JEDFLAMM_00916 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JEDFLAMM_00917 2.7e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JEDFLAMM_00918 3.9e-93 S Protein of unknown function (DUF1697)
JEDFLAMM_00919 6.4e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JEDFLAMM_00920 1.1e-50 S LemA family
JEDFLAMM_00921 7.5e-172 clcA_2 P Chloride transporter, ClC family
JEDFLAMM_00922 1.8e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
JEDFLAMM_00923 3.7e-131 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
JEDFLAMM_00924 6.8e-249 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
JEDFLAMM_00925 1.4e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
JEDFLAMM_00926 3.5e-110 cps4C M biosynthesis protein
JEDFLAMM_00927 1.3e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
JEDFLAMM_00928 2.7e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
JEDFLAMM_00929 2.4e-220 rgpAc GT4 M group 1 family protein
JEDFLAMM_00930 3.7e-210 wcoF M Glycosyltransferase, group 1 family protein
JEDFLAMM_00931 4.2e-133 M transferase activity, transferring glycosyl groups
JEDFLAMM_00932 6.7e-139 sacB GT2,GT4 M Stealth protein CR3, conserved region 3
JEDFLAMM_00933 3.9e-123 M Glycosyltransferase, group 2 family protein
JEDFLAMM_00934 8.9e-152 M Glycosyltransferase like family 2
JEDFLAMM_00935 1e-170
JEDFLAMM_00936 7e-251 epsU S Polysaccharide biosynthesis protein
JEDFLAMM_00937 1.5e-159 S Acyltransferase family
JEDFLAMM_00938 1.3e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
JEDFLAMM_00939 5.1e-182 wbbI M transferase activity, transferring glycosyl groups
JEDFLAMM_00941 6.2e-151 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JEDFLAMM_00942 1.4e-107 pgm G Belongs to the phosphoglycerate mutase family
JEDFLAMM_00943 1.4e-107 G Belongs to the phosphoglycerate mutase family
JEDFLAMM_00944 4.8e-108 G Belongs to the phosphoglycerate mutase family
JEDFLAMM_00945 2.7e-197 S hmm pf01594
JEDFLAMM_00946 8e-287 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JEDFLAMM_00947 4.9e-39 S granule-associated protein
JEDFLAMM_00948 3.1e-284 S unusual protein kinase
JEDFLAMM_00949 4.5e-101 estA E Lysophospholipase L1 and related esterases
JEDFLAMM_00950 1e-156 rssA S Phospholipase, patatin family
JEDFLAMM_00951 2.7e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
JEDFLAMM_00952 7.4e-250 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
JEDFLAMM_00953 3.3e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JEDFLAMM_00954 4.5e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JEDFLAMM_00955 4.5e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JEDFLAMM_00956 0.0 S the current gene model (or a revised gene model) may contain a frame shift
JEDFLAMM_00957 7.9e-225 2.7.13.3 T protein histidine kinase activity
JEDFLAMM_00958 9.8e-204 hpk9 2.7.13.3 T protein histidine kinase activity
JEDFLAMM_00959 6.6e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
JEDFLAMM_00960 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JEDFLAMM_00961 1.1e-211 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JEDFLAMM_00962 0.0 lpdA 1.8.1.4 C Dehydrogenase
JEDFLAMM_00963 2e-244 3.5.1.28 NU amidase activity
JEDFLAMM_00964 0.0 3.5.1.28 NU amidase activity
JEDFLAMM_00965 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
JEDFLAMM_00966 5.4e-15 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JEDFLAMM_00967 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JEDFLAMM_00968 2.2e-146 ycdO P periplasmic lipoprotein involved in iron transport
JEDFLAMM_00969 1.1e-231 ycdB P peroxidase
JEDFLAMM_00970 3.6e-278 ywbL P COG0672 High-affinity Fe2 Pb2 permease
JEDFLAMM_00971 1.1e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JEDFLAMM_00972 3e-24 tatA U protein secretion
JEDFLAMM_00973 4.7e-213 msmX P Belongs to the ABC transporter superfamily
JEDFLAMM_00974 2.2e-151 malG P ABC transporter (Permease
JEDFLAMM_00975 4.4e-250 malF P ABC transporter (Permease
JEDFLAMM_00976 3.9e-229 malX G ABC transporter
JEDFLAMM_00977 2.1e-156 malR K Transcriptional regulator
JEDFLAMM_00978 8.6e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
JEDFLAMM_00979 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JEDFLAMM_00980 2.4e-22
JEDFLAMM_00981 1.8e-08
JEDFLAMM_00982 1.9e-186 lplA 6.3.1.20 H Lipoate-protein ligase
JEDFLAMM_00983 3.5e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
JEDFLAMM_00984 0.0 pepN 3.4.11.2 E aminopeptidase
JEDFLAMM_00985 7.1e-113 phoU P Plays a role in the regulation of phosphate uptake
JEDFLAMM_00986 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JEDFLAMM_00987 2.6e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JEDFLAMM_00988 1.3e-154 pstA P phosphate transport system permease
JEDFLAMM_00989 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
JEDFLAMM_00990 2.4e-156 pstS P phosphate
JEDFLAMM_00991 2.4e-245 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
JEDFLAMM_00992 5.5e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
JEDFLAMM_00993 1.5e-43 yktA S Belongs to the UPF0223 family
JEDFLAMM_00994 9.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JEDFLAMM_00995 3.3e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JEDFLAMM_00996 2.1e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JEDFLAMM_00997 3.5e-244 XK27_04775 S hemerythrin HHE cation binding domain
JEDFLAMM_00998 2.3e-34 M1-755 P Hemerythrin HHE cation binding domain protein
JEDFLAMM_00999 1.4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
JEDFLAMM_01000 3.6e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JEDFLAMM_01001 1.2e-140 S haloacid dehalogenase-like hydrolase
JEDFLAMM_01002 1.5e-239 metY 2.5.1.49 E o-acetylhomoserine
JEDFLAMM_01003 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JEDFLAMM_01004 3.1e-240 agcS E (Alanine) symporter
JEDFLAMM_01005 2.8e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JEDFLAMM_01006 4e-167 bglC K Transcriptional regulator
JEDFLAMM_01007 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
JEDFLAMM_01008 1.1e-81 yecS P ABC transporter (Permease
JEDFLAMM_01009 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
JEDFLAMM_01010 4.7e-242 nylA 3.5.1.4 J Belongs to the amidase family
JEDFLAMM_01011 9.8e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JEDFLAMM_01012 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JEDFLAMM_01014 1.3e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JEDFLAMM_01015 3.2e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JEDFLAMM_01016 2.7e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
JEDFLAMM_01017 4.4e-133 S TraX protein
JEDFLAMM_01018 7.3e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JEDFLAMM_01019 1.5e-267 S Psort location CytoplasmicMembrane, score
JEDFLAMM_01020 1.5e-231 dinF V Mate efflux family protein
JEDFLAMM_01021 3.5e-177 yclQ P ABC-type enterochelin transport system, periplasmic component
JEDFLAMM_01022 1.2e-154 S von Willebrand factor (vWF) type A domain
JEDFLAMM_01023 0.0 V Type III restriction enzyme, res subunit
JEDFLAMM_01024 1.4e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
JEDFLAMM_01025 1.6e-132 2.4.2.3 F Phosphorylase superfamily
JEDFLAMM_01027 6.8e-187 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
JEDFLAMM_01028 1.1e-195 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JEDFLAMM_01029 3.1e-159 czcD P cation diffusion facilitator family transporter
JEDFLAMM_01030 7.9e-94 K Transcriptional regulator, TetR family
JEDFLAMM_01031 4.1e-70 S Protein of unknown function with HXXEE motif
JEDFLAMM_01032 1.3e-46
JEDFLAMM_01033 6.4e-72 L Transposase
JEDFLAMM_01034 0.0 S Signal peptide protein, YSIRK family
JEDFLAMM_01035 4.1e-127 K response regulator
JEDFLAMM_01036 1.2e-175 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
JEDFLAMM_01037 4.5e-50 L the current gene model (or a revised gene model) may contain a frame shift
JEDFLAMM_01038 9.7e-149 cbiO2 P ABC transporter, ATP-binding protein
JEDFLAMM_01039 2.9e-156 P abc transporter atp-binding protein
JEDFLAMM_01040 1.7e-132 cbiQ P cobalt transport
JEDFLAMM_01041 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
JEDFLAMM_01042 1.7e-140 S Phenazine biosynthesis protein
JEDFLAMM_01043 1.7e-108 magIII L Base excision DNA repair protein, HhH-GPD family
JEDFLAMM_01044 2.3e-260 proWX P ABC transporter
JEDFLAMM_01045 3.5e-129 proV E abc transporter atp-binding protein
JEDFLAMM_01046 7.7e-144 1.6.5.2 GM epimerase
JEDFLAMM_01047 6.2e-68 mgrA K Transcriptional regulator, MarR family
JEDFLAMM_01048 2.7e-79 S Macro domain
JEDFLAMM_01049 7.6e-96 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
JEDFLAMM_01050 4.1e-18 C Pyridoxamine 5'-phosphate oxidase
JEDFLAMM_01051 6.3e-189 XK27_10075 S abc transporter atp-binding protein
JEDFLAMM_01052 0.0 V abc transporter atp-binding protein
JEDFLAMM_01053 3.6e-297 V abc transporter atp-binding protein
JEDFLAMM_01054 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
JEDFLAMM_01056 4.4e-283 S Protein of unknown function (DUF3114)
JEDFLAMM_01057 6.5e-99 2.3.1.128 K Acetyltransferase GNAT Family
JEDFLAMM_01058 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JEDFLAMM_01059 1.6e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
JEDFLAMM_01060 3.4e-179 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
JEDFLAMM_01061 4.1e-185 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JEDFLAMM_01062 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JEDFLAMM_01063 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JEDFLAMM_01064 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JEDFLAMM_01065 3.5e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JEDFLAMM_01066 5.5e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JEDFLAMM_01067 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JEDFLAMM_01070 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JEDFLAMM_01071 1.9e-170 vraS 2.7.13.3 T Histidine kinase
JEDFLAMM_01072 6.6e-117 yvqF S Membrane
JEDFLAMM_01073 4.1e-104 kcsA P Ion transport protein
JEDFLAMM_01074 1.4e-291 prkC 2.7.11.1 KLT serine threonine protein kinase
JEDFLAMM_01075 1.3e-134 stp 3.1.3.16 T phosphatase
JEDFLAMM_01076 2.7e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JEDFLAMM_01077 3.1e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JEDFLAMM_01078 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JEDFLAMM_01079 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
JEDFLAMM_01080 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JEDFLAMM_01081 2.4e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JEDFLAMM_01082 2.7e-146 XK27_02985 S overlaps another CDS with the same product name
JEDFLAMM_01083 2.6e-146 supH S overlaps another CDS with the same product name
JEDFLAMM_01084 5.6e-62 yvoA_1 K Transcriptional
JEDFLAMM_01085 1.8e-119 skfE V abc transporter atp-binding protein
JEDFLAMM_01086 1.1e-128 V Psort location CytoplasmicMembrane, score
JEDFLAMM_01087 1.2e-171 oppF P Belongs to the ABC transporter superfamily
JEDFLAMM_01088 4.2e-203 oppD P Belongs to the ABC transporter superfamily
JEDFLAMM_01089 2.9e-165 amiD P ABC transporter (Permease
JEDFLAMM_01090 1.5e-275 amiC P ABC transporter (Permease
JEDFLAMM_01091 0.0 amiA E ABC transporter, substrate-binding protein, family 5
JEDFLAMM_01092 0.0 amiA E ABC transporter, substrate-binding protein, family 5
JEDFLAMM_01093 1.5e-175 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
JEDFLAMM_01094 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
JEDFLAMM_01095 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JEDFLAMM_01096 1.4e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
JEDFLAMM_01097 7.1e-101 yjbK S Adenylate cyclase
JEDFLAMM_01098 5.1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JEDFLAMM_01099 5.6e-203 iscS 2.8.1.7 E Cysteine desulfurase
JEDFLAMM_01100 8.2e-60 XK27_04120 S Putative amino acid metabolism
JEDFLAMM_01101 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JEDFLAMM_01102 3.7e-128 puuD T peptidase C26
JEDFLAMM_01103 1.2e-118 radC E Belongs to the UPF0758 family
JEDFLAMM_01104 1.1e-292 rgpF M Rhamnan synthesis protein F
JEDFLAMM_01105 1.4e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JEDFLAMM_01106 2.9e-140 rgpC GM Transport permease protein
JEDFLAMM_01107 1.4e-170 rgpB GT2 M Glycosyltransferase, group 2 family protein
JEDFLAMM_01108 1e-223 rgpA GT4 M Domain of unknown function (DUF1972)
JEDFLAMM_01109 6.6e-229 GT4 M transferase activity, transferring glycosyl groups
JEDFLAMM_01110 1.6e-222 M Psort location CytoplasmicMembrane, score
JEDFLAMM_01111 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
JEDFLAMM_01112 1.3e-91 S Psort location CytoplasmicMembrane, score
JEDFLAMM_01113 1.9e-149 2.4.1.60 S Glycosyltransferase group 2 family protein
JEDFLAMM_01114 1.9e-43 S Uncharacterized conserved protein (DUF2304)
JEDFLAMM_01115 7e-127 arnC M group 2 family protein
JEDFLAMM_01116 1.3e-176 cpsIaJ S Glycosyltransferase like family 2
JEDFLAMM_01117 5.1e-157 M Glycosyltransferase, group 2 family protein
JEDFLAMM_01118 9.3e-226 amrA S membrane protein involved in the export of O-antigen and teichoic acid
JEDFLAMM_01119 1.7e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JEDFLAMM_01120 2.4e-262 S Glucosyl transferase GtrII
JEDFLAMM_01121 8e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
JEDFLAMM_01122 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
JEDFLAMM_01123 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JEDFLAMM_01124 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JEDFLAMM_01125 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JEDFLAMM_01126 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JEDFLAMM_01127 2.7e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
JEDFLAMM_01128 6.8e-209 arcT 2.6.1.1 E Aminotransferase
JEDFLAMM_01129 5.9e-138 ET Belongs to the bacterial solute-binding protein 3 family
JEDFLAMM_01130 5.8e-133 ET ABC transporter
JEDFLAMM_01131 3.6e-79 mutT 3.6.1.55 F Nudix family
JEDFLAMM_01132 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JEDFLAMM_01134 3.6e-163 S CAAX amino terminal protease family protein
JEDFLAMM_01135 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
JEDFLAMM_01136 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
JEDFLAMM_01137 1.7e-17 XK27_00735
JEDFLAMM_01138 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JEDFLAMM_01140 1.4e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JEDFLAMM_01141 9.8e-10 O ADP-ribosylglycohydrolase
JEDFLAMM_01142 1.1e-60 paaI Q protein possibly involved in aromatic compounds catabolism
JEDFLAMM_01143 1.6e-61 ycaO O OsmC-like protein
JEDFLAMM_01145 3.4e-150 EG Permeases of the drug metabolite transporter (DMT) superfamily
JEDFLAMM_01146 8.5e-08 N PFAM Uncharacterised protein family UPF0150
JEDFLAMM_01147 1.9e-110 serB 3.1.3.3 E phosphoserine phosphatase
JEDFLAMM_01148 6.4e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JEDFLAMM_01149 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JEDFLAMM_01150 3.5e-97 3.1.3.18 S IA, variant 1
JEDFLAMM_01151 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
JEDFLAMM_01152 3.5e-56 lrgA S Effector of murein hydrolase LrgA
JEDFLAMM_01154 5.4e-68 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
JEDFLAMM_01155 1.7e-218 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JEDFLAMM_01156 1e-104 wecD M Acetyltransferase (GNAT) domain
JEDFLAMM_01157 8.8e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JEDFLAMM_01158 9.8e-158 GK ROK family
JEDFLAMM_01159 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
JEDFLAMM_01160 1.6e-144 XK27_08050 O HflC and HflK could regulate a protease
JEDFLAMM_01161 4.4e-205 potD P spermidine putrescine ABC transporter
JEDFLAMM_01162 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
JEDFLAMM_01163 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
JEDFLAMM_01164 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JEDFLAMM_01165 1.4e-167 murB 1.3.1.98 M cell wall formation
JEDFLAMM_01166 3.7e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JEDFLAMM_01167 5e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JEDFLAMM_01168 1.6e-290 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
JEDFLAMM_01169 3.2e-144 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JEDFLAMM_01170 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
JEDFLAMM_01171 0.0 ydaO E amino acid
JEDFLAMM_01172 2e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JEDFLAMM_01173 1.5e-36 ylqC L Belongs to the UPF0109 family
JEDFLAMM_01174 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JEDFLAMM_01176 4.8e-201 2.7.13.3 T protein histidine kinase activity
JEDFLAMM_01177 2.6e-124 agrA KT phosphorelay signal transduction system
JEDFLAMM_01178 5.5e-165 O protein import
JEDFLAMM_01179 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
JEDFLAMM_01180 3.7e-17 yjdB S Domain of unknown function (DUF4767)
JEDFLAMM_01181 2.7e-199 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JEDFLAMM_01183 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
JEDFLAMM_01184 3.7e-71 S QueT transporter
JEDFLAMM_01186 4.5e-172 yfjR K regulation of single-species biofilm formation
JEDFLAMM_01188 6.9e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JEDFLAMM_01189 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JEDFLAMM_01190 1.1e-84 ccl S cog cog4708
JEDFLAMM_01191 5.3e-162 rbn E Belongs to the UPF0761 family
JEDFLAMM_01192 4.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
JEDFLAMM_01193 3e-232 ytoI K transcriptional regulator containing CBS domains
JEDFLAMM_01194 8.2e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
JEDFLAMM_01195 2.1e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JEDFLAMM_01196 0.0 comEC S Competence protein ComEC
JEDFLAMM_01197 4.3e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
JEDFLAMM_01198 3.2e-141 plsC 2.3.1.51 I Acyltransferase
JEDFLAMM_01199 1.1e-148 nodB3 G Polysaccharide deacetylase
JEDFLAMM_01200 1.8e-139 yabB 2.1.1.223 L Methyltransferase
JEDFLAMM_01201 6.6e-41 yazA L endonuclease containing a URI domain
JEDFLAMM_01202 1.4e-244 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JEDFLAMM_01203 1.6e-152 corA P CorA-like protein
JEDFLAMM_01204 1.4e-60 yjqA S Bacterial PH domain
JEDFLAMM_01205 1.7e-99 thiT S Thiamine transporter
JEDFLAMM_01206 6.6e-151 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JEDFLAMM_01207 7.2e-193 yjbB G Permeases of the major facilitator superfamily
JEDFLAMM_01208 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JEDFLAMM_01210 1.6e-117 ywaF S Integral membrane protein (intg_mem_TP0381)
JEDFLAMM_01211 7.8e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JEDFLAMM_01215 3.3e-155 cjaA ET ABC transporter substrate-binding protein
JEDFLAMM_01216 2e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
JEDFLAMM_01217 1.5e-113 P ABC transporter (Permease
JEDFLAMM_01218 3e-114 papP P ABC transporter (Permease
JEDFLAMM_01219 5.1e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JEDFLAMM_01220 1.4e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
JEDFLAMM_01221 0.0 copA 3.6.3.54 P P-type ATPase
JEDFLAMM_01222 1.8e-72 copY K negative regulation of transcription, DNA-templated
JEDFLAMM_01223 3.2e-164 EGP Major facilitator Superfamily
JEDFLAMM_01227 3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JEDFLAMM_01228 1.9e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JEDFLAMM_01229 8.8e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
JEDFLAMM_01230 7.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JEDFLAMM_01231 3.9e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JEDFLAMM_01232 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
JEDFLAMM_01233 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JEDFLAMM_01234 6.5e-17 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
JEDFLAMM_01235 7.5e-59
JEDFLAMM_01236 0.0 ctpE P E1-E2 ATPase
JEDFLAMM_01237 4e-47
JEDFLAMM_01238 1.1e-49
JEDFLAMM_01239 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JEDFLAMM_01241 1.9e-124 V abc transporter atp-binding protein
JEDFLAMM_01242 0.0 V ABC transporter (Permease
JEDFLAMM_01243 4.7e-126 K transcriptional regulator, MerR family
JEDFLAMM_01244 9.2e-104 dnaQ 2.7.7.7 L DNA polymerase III
JEDFLAMM_01245 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
JEDFLAMM_01246 2.1e-63 XK27_02560 S cog cog2151
JEDFLAMM_01247 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JEDFLAMM_01248 4.4e-222 ytfP S Flavoprotein
JEDFLAMM_01250 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JEDFLAMM_01251 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
JEDFLAMM_01252 3.9e-174 ecsB U Bacterial ABC transporter protein EcsB
JEDFLAMM_01253 3.7e-131 ecsA V abc transporter atp-binding protein
JEDFLAMM_01254 2.3e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JEDFLAMM_01255 6.9e-07
JEDFLAMM_01258 1.6e-103
JEDFLAMM_01260 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
JEDFLAMM_01262 1.3e-199 ylbM S Belongs to the UPF0348 family
JEDFLAMM_01263 6.5e-139 yqeM Q Methyltransferase domain protein
JEDFLAMM_01264 2.2e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JEDFLAMM_01265 7.6e-83 entB 3.5.1.19 Q Isochorismatase family
JEDFLAMM_01266 6e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JEDFLAMM_01267 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JEDFLAMM_01268 7.7e-49 yhbY J RNA-binding protein
JEDFLAMM_01269 3.5e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JEDFLAMM_01270 1.4e-98 yqeG S hydrolase of the HAD superfamily
JEDFLAMM_01271 1.2e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JEDFLAMM_01272 2.1e-64
JEDFLAMM_01273 3.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JEDFLAMM_01274 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JEDFLAMM_01275 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JEDFLAMM_01276 9.6e-235 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
JEDFLAMM_01277 3.2e-186 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
JEDFLAMM_01278 8.2e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
JEDFLAMM_01279 6.7e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
JEDFLAMM_01280 3.7e-292 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JEDFLAMM_01281 1.2e-97 pncA Q isochorismatase
JEDFLAMM_01282 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JEDFLAMM_01283 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
JEDFLAMM_01284 1.2e-74 XK27_03180 T universal stress protein
JEDFLAMM_01286 1.7e-156 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JEDFLAMM_01287 5.5e-10 MU outer membrane autotransporter barrel domain protein
JEDFLAMM_01288 2.9e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
JEDFLAMM_01289 6.6e-142 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
JEDFLAMM_01291 7.1e-26
JEDFLAMM_01292 0.0 yjcE P NhaP-type Na H and K H antiporters
JEDFLAMM_01294 2.2e-96 ytqB J (SAM)-dependent
JEDFLAMM_01295 2.1e-182 yhcC S radical SAM protein
JEDFLAMM_01296 4.2e-187 ylbL T Belongs to the peptidase S16 family
JEDFLAMM_01297 3.9e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JEDFLAMM_01298 2.9e-105 rsmD 2.1.1.171 L Methyltransferase
JEDFLAMM_01299 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JEDFLAMM_01300 5e-10 S Protein of unknown function (DUF4059)
JEDFLAMM_01301 5.2e-128 tcyN 3.6.3.21 E abc transporter atp-binding protein
JEDFLAMM_01302 8.6e-157 yxeN P ABC transporter (Permease
JEDFLAMM_01303 7.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
JEDFLAMM_01304 8e-35
JEDFLAMM_01305 5.6e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JEDFLAMM_01306 0.0 pflB 2.3.1.54 C formate acetyltransferase'
JEDFLAMM_01307 6e-143 cah 4.2.1.1 P carbonic anhydrase
JEDFLAMM_01308 1.9e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JEDFLAMM_01310 3.2e-167 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
JEDFLAMM_01311 1.4e-136 cppA E CppA N-terminal
JEDFLAMM_01312 1.6e-96 V CAAX protease self-immunity
JEDFLAMM_01313 9.5e-158 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
JEDFLAMM_01314 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JEDFLAMM_01315 1.6e-43 spiA K sequence-specific DNA binding
JEDFLAMM_01321 0.0 mdlB V abc transporter atp-binding protein
JEDFLAMM_01322 0.0 mdlA V abc transporter atp-binding protein
JEDFLAMM_01324 1.5e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
JEDFLAMM_01325 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JEDFLAMM_01326 1.8e-61 yutD J protein conserved in bacteria
JEDFLAMM_01327 4.6e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JEDFLAMM_01329 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JEDFLAMM_01330 2e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JEDFLAMM_01331 0.0 ftsI 3.4.16.4 M penicillin-binding protein
JEDFLAMM_01332 4e-45 ftsL D cell division protein FtsL
JEDFLAMM_01333 3.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JEDFLAMM_01334 2.8e-100
JEDFLAMM_01337 1.3e-37 yhaI J Protein of unknown function (DUF805)
JEDFLAMM_01338 1.3e-61 yhaI J Protein of unknown function (DUF805)
JEDFLAMM_01339 6.6e-32 yhaI J Protein of unknown function (DUF805)
JEDFLAMM_01340 6.2e-64 yhaI J Membrane
JEDFLAMM_01341 9.3e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JEDFLAMM_01342 1.1e-139 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JEDFLAMM_01343 1.9e-284 XK27_00765
JEDFLAMM_01344 4.4e-132 ecsA_2 V abc transporter atp-binding protein
JEDFLAMM_01345 8.1e-126 S Protein of unknown function (DUF554)
JEDFLAMM_01346 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JEDFLAMM_01347 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JEDFLAMM_01348 8e-244 2.7.13.3 T protein histidine kinase activity
JEDFLAMM_01349 1e-232 dcuS 2.7.13.3 T protein histidine kinase activity
JEDFLAMM_01350 6.8e-14
JEDFLAMM_01353 3.8e-145 V Psort location CytoplasmicMembrane, score
JEDFLAMM_01355 6.6e-298 O MreB/Mbl protein
JEDFLAMM_01356 1.6e-110 liaI S membrane
JEDFLAMM_01357 1.7e-73 XK27_02470 K LytTr DNA-binding domain protein
JEDFLAMM_01358 2e-308 KT response to antibiotic
JEDFLAMM_01359 3e-114 yebC M Membrane
JEDFLAMM_01360 2.6e-258 XK27_03190 S hydrolases of the HAD superfamily
JEDFLAMM_01361 1.2e-177 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JEDFLAMM_01363 2.9e-31 yozG K Transcriptional regulator
JEDFLAMM_01367 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JEDFLAMM_01368 1.2e-202 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JEDFLAMM_01369 2.3e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JEDFLAMM_01370 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JEDFLAMM_01371 2.8e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JEDFLAMM_01372 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JEDFLAMM_01374 1.4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
JEDFLAMM_01375 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
JEDFLAMM_01376 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JEDFLAMM_01377 5.4e-283 scrB 3.2.1.26 GH32 G invertase
JEDFLAMM_01378 2.7e-177 scrR K Transcriptional regulator
JEDFLAMM_01379 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JEDFLAMM_01380 1.7e-61 yqhY S protein conserved in bacteria
JEDFLAMM_01381 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JEDFLAMM_01382 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
JEDFLAMM_01383 1.8e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
JEDFLAMM_01384 8.6e-34 blpT
JEDFLAMM_01388 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JEDFLAMM_01389 2.2e-168 corA P COG0598 Mg2 and Co2 transporters
JEDFLAMM_01390 2.9e-122 XK27_01040 S Protein of unknown function (DUF1129)
JEDFLAMM_01392 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JEDFLAMM_01393 1.6e-80 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JEDFLAMM_01394 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
JEDFLAMM_01395 2.9e-43 XK27_05745
JEDFLAMM_01396 1.1e-222 mutY L A G-specific adenine glycosylase
JEDFLAMM_01398 7.6e-10
JEDFLAMM_01400 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JEDFLAMM_01401 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JEDFLAMM_01402 6.1e-94 cvpA S toxin biosynthetic process
JEDFLAMM_01403 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JEDFLAMM_01404 2.1e-152 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JEDFLAMM_01405 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JEDFLAMM_01406 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JEDFLAMM_01407 8.2e-46 azlD S branched-chain amino acid
JEDFLAMM_01408 3e-114 azlC E AzlC protein
JEDFLAMM_01409 4.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JEDFLAMM_01410 1.3e-70 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JEDFLAMM_01411 7.9e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
JEDFLAMM_01412 1.5e-33 ykzG S Belongs to the UPF0356 family
JEDFLAMM_01413 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JEDFLAMM_01414 8e-114 pscB M CHAP domain protein
JEDFLAMM_01415 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
JEDFLAMM_01416 2.5e-62 glnR K Transcriptional regulator
JEDFLAMM_01417 3e-87 S Fusaric acid resistance protein-like
JEDFLAMM_01418 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JEDFLAMM_01419 5.3e-119
JEDFLAMM_01420 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
JEDFLAMM_01421 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JEDFLAMM_01422 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JEDFLAMM_01423 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JEDFLAMM_01424 4e-142 purR 2.4.2.7 F operon repressor
JEDFLAMM_01425 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
JEDFLAMM_01426 1.1e-170 rmuC S RmuC domain protein
JEDFLAMM_01427 2.3e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
JEDFLAMM_01428 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JEDFLAMM_01429 2.1e-160 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JEDFLAMM_01431 5.8e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JEDFLAMM_01432 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JEDFLAMM_01433 1.6e-143 tatD L Hydrolase, tatd
JEDFLAMM_01434 2.1e-73 yccU S CoA-binding protein
JEDFLAMM_01435 2.4e-50 trxA O Belongs to the thioredoxin family
JEDFLAMM_01436 6e-143 S Macro domain protein
JEDFLAMM_01437 1.8e-61 L thioesterase
JEDFLAMM_01438 3.4e-47 bta 1.8.1.8 CO cell redox homeostasis
JEDFLAMM_01439 6.7e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
JEDFLAMM_01440 4e-18 terZ T TerD domain
JEDFLAMM_01441 1e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JEDFLAMM_01442 2.6e-186 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JEDFLAMM_01443 0.0 dnaE 2.7.7.7 L DNA polymerase
JEDFLAMM_01444 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JEDFLAMM_01445 3.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JEDFLAMM_01446 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JEDFLAMM_01447 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JEDFLAMM_01448 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JEDFLAMM_01449 8.9e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
JEDFLAMM_01451 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JEDFLAMM_01452 1.8e-96 ypmS S Protein conserved in bacteria
JEDFLAMM_01453 4.6e-160 ypmR E COG2755 Lysophospholipase L1 and related esterases
JEDFLAMM_01454 2e-144 DegV S DegV family
JEDFLAMM_01455 1.5e-300 recN L May be involved in recombinational repair of damaged DNA
JEDFLAMM_01456 7e-72 argR K Regulates arginine biosynthesis genes
JEDFLAMM_01457 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
JEDFLAMM_01458 4.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JEDFLAMM_01459 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JEDFLAMM_01460 5.6e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JEDFLAMM_01462 4.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JEDFLAMM_01463 3.2e-124 dnaD
JEDFLAMM_01464 3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JEDFLAMM_01465 3.8e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JEDFLAMM_01466 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
JEDFLAMM_01467 2.6e-65 GnaT 2.5.1.16 K acetyltransferase
JEDFLAMM_01468 5.2e-87 Q Methyltransferase domain
JEDFLAMM_01469 7.6e-24 Q Methyltransferase domain
JEDFLAMM_01470 1.6e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JEDFLAMM_01471 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JEDFLAMM_01472 1.7e-111 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
JEDFLAMM_01473 3.5e-244 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JEDFLAMM_01474 2.4e-235 rodA D Belongs to the SEDS family
JEDFLAMM_01475 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JEDFLAMM_01476 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JEDFLAMM_01477 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JEDFLAMM_01478 3e-179 XK27_08075 M glycosyl transferase family 2
JEDFLAMM_01479 5e-99 S Carbohydrate-binding domain-containing protein Cthe_2159
JEDFLAMM_01480 1.2e-143 P molecular chaperone
JEDFLAMM_01481 1e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
JEDFLAMM_01483 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
JEDFLAMM_01484 1.1e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JEDFLAMM_01485 2.8e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JEDFLAMM_01486 1.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JEDFLAMM_01487 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JEDFLAMM_01488 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JEDFLAMM_01489 3.2e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JEDFLAMM_01490 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JEDFLAMM_01491 3.2e-178 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JEDFLAMM_01492 5.5e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JEDFLAMM_01493 2.8e-61 XK27_08085
JEDFLAMM_01494 3.1e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
JEDFLAMM_01495 9.3e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
JEDFLAMM_01496 2.3e-116 ylfI S tigr01906
JEDFLAMM_01497 2.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JEDFLAMM_01498 3.4e-140 fat 3.1.2.21 I Acyl-ACP thioesterase
JEDFLAMM_01499 1.9e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
JEDFLAMM_01500 2.9e-30 KT response to antibiotic
JEDFLAMM_01502 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JEDFLAMM_01503 1.9e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JEDFLAMM_01504 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JEDFLAMM_01505 2.5e-258 S phospholipase Carboxylesterase
JEDFLAMM_01506 6.7e-201 yurR 1.4.5.1 E oxidoreductase
JEDFLAMM_01507 8.2e-143 zupT P Mediates zinc uptake. May also transport other divalent cations
JEDFLAMM_01508 1.3e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JEDFLAMM_01509 6.4e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
JEDFLAMM_01510 2.3e-64 gtrA S GtrA-like protein
JEDFLAMM_01511 1.6e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JEDFLAMM_01512 4.2e-162 ybbR S Protein conserved in bacteria
JEDFLAMM_01513 3.9e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JEDFLAMM_01514 3.8e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
JEDFLAMM_01515 8.7e-150 cobQ S glutamine amidotransferase
JEDFLAMM_01516 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JEDFLAMM_01517 1.7e-131 pip 1.11.1.10 S Alpha beta hydrolase
JEDFLAMM_01518 1.6e-39 MA20_06245 S yiaA/B two helix domain
JEDFLAMM_01519 0.0 uup S abc transporter atp-binding protein
JEDFLAMM_01520 6.8e-113 udk 2.7.1.48 F Cytidine monophosphokinase
JEDFLAMM_01521 1.5e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
JEDFLAMM_01522 8.4e-226 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
JEDFLAMM_01523 2.7e-153 XK27_05675 S Esterase
JEDFLAMM_01524 6.1e-162 XK27_05670 S Putative esterase
JEDFLAMM_01525 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
JEDFLAMM_01526 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JEDFLAMM_01527 3e-38 ptsH G phosphocarrier protein Hpr
JEDFLAMM_01528 8.8e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
JEDFLAMM_01529 2.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
JEDFLAMM_01530 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JEDFLAMM_01531 6.5e-34 nrdH O Glutaredoxin
JEDFLAMM_01532 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JEDFLAMM_01533 3.2e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JEDFLAMM_01534 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JEDFLAMM_01535 8.4e-138 divIVA D Cell division initiation protein
JEDFLAMM_01536 3.6e-143 ylmH S conserved protein, contains S4-like domain
JEDFLAMM_01537 2.9e-30 yggT D integral membrane protein
JEDFLAMM_01538 2.2e-86 sepF D cell septum assembly
JEDFLAMM_01539 7.3e-121 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JEDFLAMM_01540 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JEDFLAMM_01541 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JEDFLAMM_01542 4.1e-104 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JEDFLAMM_01543 7.2e-09 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JEDFLAMM_01544 1.2e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JEDFLAMM_01545 3.9e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JEDFLAMM_01547 0.0 typA T GTP-binding protein TypA
JEDFLAMM_01548 1e-176 glk 2.7.1.2 G Glucokinase
JEDFLAMM_01549 7.1e-27 yqgQ S protein conserved in bacteria
JEDFLAMM_01550 3.4e-79 perR P Belongs to the Fur family
JEDFLAMM_01551 2.5e-89 dps P Belongs to the Dps family
JEDFLAMM_01552 4.1e-105 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
JEDFLAMM_01553 5.8e-165 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
JEDFLAMM_01554 1.6e-111 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
JEDFLAMM_01555 2.1e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
JEDFLAMM_01556 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JEDFLAMM_01557 5.6e-65 S Domain of unknown function (DUF4430)
JEDFLAMM_01558 4.1e-73 S Psort location CytoplasmicMembrane, score
JEDFLAMM_01559 1.6e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
JEDFLAMM_01560 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
JEDFLAMM_01561 2.1e-171 sitA P Belongs to the bacterial solute-binding protein 9 family
JEDFLAMM_01562 8.5e-119 sirR K iron dependent repressor
JEDFLAMM_01563 4e-135 htpX O Belongs to the peptidase M48B family
JEDFLAMM_01564 7.7e-92 lemA S LemA family
JEDFLAMM_01565 4e-176 spd F DNA RNA non-specific endonuclease
JEDFLAMM_01566 1.1e-32 2.4.1.21 GT5 M Right handed beta helix region
JEDFLAMM_01567 1.2e-76 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
JEDFLAMM_01568 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JEDFLAMM_01569 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JEDFLAMM_01570 4.8e-235 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JEDFLAMM_01571 1.5e-236 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
JEDFLAMM_01573 3e-60 divIC D Septum formation initiator
JEDFLAMM_01574 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JEDFLAMM_01575 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JEDFLAMM_01576 8.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JEDFLAMM_01577 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JEDFLAMM_01578 1.1e-29 yyzM S Protein conserved in bacteria
JEDFLAMM_01579 4.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JEDFLAMM_01580 4.5e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JEDFLAMM_01581 6.5e-134 parB K Belongs to the ParB family
JEDFLAMM_01582 2.7e-206 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
JEDFLAMM_01583 2.3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JEDFLAMM_01584 2.4e-119 yoaK S Protein of unknown function (DUF1275)
JEDFLAMM_01588 0.0 XK27_10405 S Bacterial membrane protein YfhO
JEDFLAMM_01589 4.3e-305 ybiT S abc transporter atp-binding protein
JEDFLAMM_01590 7.1e-153 yvjA S membrane
JEDFLAMM_01591 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JEDFLAMM_01592 2.8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JEDFLAMM_01593 2.7e-41 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JEDFLAMM_01594 5.4e-142 L Transposase and inactivated derivatives
JEDFLAMM_01595 5.3e-74 L Transposase
JEDFLAMM_01596 6.5e-80 L Transposase
JEDFLAMM_01597 1e-58 S BON domain
JEDFLAMM_01598 2.4e-34 pyrC 3.5.2.3 F dihydroorotase
JEDFLAMM_01599 2e-24 lapA Q Transposase
JEDFLAMM_01600 2.4e-47 L Putative transposase of IS4/5 family (DUF4096)
JEDFLAMM_01601 1.6e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JEDFLAMM_01603 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
JEDFLAMM_01604 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JEDFLAMM_01607 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JEDFLAMM_01609 8.2e-137 IQ Acetoin reductase
JEDFLAMM_01610 2.6e-43 pspE P Rhodanese-like protein
JEDFLAMM_01611 7.9e-70 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JEDFLAMM_01612 1e-223 XK27_05470 E Methionine synthase
JEDFLAMM_01613 1.1e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JEDFLAMM_01614 1.3e-228 T PhoQ Sensor
JEDFLAMM_01615 1.1e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JEDFLAMM_01616 6.3e-143 S TraX protein
JEDFLAMM_01617 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JEDFLAMM_01618 7.8e-157 dprA LU DNA protecting protein DprA
JEDFLAMM_01619 1.1e-151 GK ROK family
JEDFLAMM_01620 4.3e-130 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JEDFLAMM_01621 3.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JEDFLAMM_01622 4e-127 K DNA-binding helix-turn-helix protein
JEDFLAMM_01623 9.5e-89 niaR S small molecule binding protein (contains 3H domain)
JEDFLAMM_01624 2.7e-86
JEDFLAMM_01625 1e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JEDFLAMM_01626 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JEDFLAMM_01627 2.7e-126 gntR1 K transcriptional
JEDFLAMM_01628 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JEDFLAMM_01629 1.7e-94 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JEDFLAMM_01632 2.6e-10
JEDFLAMM_01638 9.6e-99 mreC M Involved in formation and maintenance of cell shape
JEDFLAMM_01639 6.1e-83 mreD M rod shape-determining protein MreD
JEDFLAMM_01640 1.9e-84 usp 3.5.1.28 CBM50 S CHAP domain
JEDFLAMM_01641 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JEDFLAMM_01642 6.7e-215 araT 2.6.1.1 E Aminotransferase
JEDFLAMM_01643 1.4e-139 recO L Involved in DNA repair and RecF pathway recombination
JEDFLAMM_01644 2.6e-175 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JEDFLAMM_01645 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JEDFLAMM_01646 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JEDFLAMM_01647 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JEDFLAMM_01648 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JEDFLAMM_01649 1.2e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JEDFLAMM_01650 1.7e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JEDFLAMM_01651 2.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JEDFLAMM_01652 1.1e-155 S CHAP domain
JEDFLAMM_01653 1.6e-238 purD 6.3.4.13 F Belongs to the GARS family
JEDFLAMM_01654 3.4e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JEDFLAMM_01655 1e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JEDFLAMM_01656 6.1e-174 1.1.1.169 H Ketopantoate reductase
JEDFLAMM_01657 3.3e-33
JEDFLAMM_01658 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JEDFLAMM_01659 2.1e-12
JEDFLAMM_01662 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JEDFLAMM_01663 3.1e-69 argR K Regulates arginine biosynthesis genes
JEDFLAMM_01664 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JEDFLAMM_01665 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JEDFLAMM_01666 6e-79 S Protein of unknown function (DUF3021)
JEDFLAMM_01667 4.2e-69 K LytTr DNA-binding domain
JEDFLAMM_01669 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JEDFLAMM_01671 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JEDFLAMM_01672 1.6e-105 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
JEDFLAMM_01673 8.8e-229 cinA 3.5.1.42 S Belongs to the CinA family
JEDFLAMM_01674 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JEDFLAMM_01675 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
JEDFLAMM_01678 1.7e-198 S Phage replication protein CRI
JEDFLAMM_01680 5.7e-36 L Transposase
JEDFLAMM_01681 0.0 M domain protein
JEDFLAMM_01682 2.8e-17
JEDFLAMM_01683 2.4e-267 D Ftsk spoiiie family protein
JEDFLAMM_01684 1.3e-58 S Bacterial protein of unknown function (DUF961)
JEDFLAMM_01685 1.8e-53 S Bacterial protein of unknown function (DUF961)
JEDFLAMM_01687 4.6e-240 S dextransucrase activity
JEDFLAMM_01688 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JEDFLAMM_01689 0.0 S dextransucrase activity
JEDFLAMM_01690 0.0 S dextransucrase activity
JEDFLAMM_01691 0.0 S dextransucrase activity
JEDFLAMM_01692 5.8e-83 S dextransucrase activity
JEDFLAMM_01693 0.0 M Putative cell wall binding repeat
JEDFLAMM_01694 1.6e-240 tcdB S dextransucrase activity
JEDFLAMM_01695 0.0 S dextransucrase activity
JEDFLAMM_01696 5.5e-63
JEDFLAMM_01697 1.3e-102 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JEDFLAMM_01698 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JEDFLAMM_01699 7.3e-307 S dextransucrase activity
JEDFLAMM_01700 0.0 S dextransucrase activity
JEDFLAMM_01701 0.0 M Putative cell wall binding repeat
JEDFLAMM_01702 5.3e-225 S dextransucrase activity
JEDFLAMM_01703 5.2e-75 KT Primase C terminal 1 (PriCT-1)
JEDFLAMM_01704 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JEDFLAMM_01705 2.2e-82 comFC S Competence protein
JEDFLAMM_01706 1.2e-247 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JEDFLAMM_01707 3.8e-108 yvyE 3.4.13.9 S YigZ family
JEDFLAMM_01708 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JEDFLAMM_01709 1.6e-112 acuB S CBS domain
JEDFLAMM_01710 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
JEDFLAMM_01711 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
JEDFLAMM_01712 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
JEDFLAMM_01713 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
JEDFLAMM_01714 2.6e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
JEDFLAMM_01715 2.7e-45 ylbG S UPF0298 protein
JEDFLAMM_01716 4.7e-68 ylbF S Belongs to the UPF0342 family
JEDFLAMM_01717 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JEDFLAMM_01718 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JEDFLAMM_01719 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
JEDFLAMM_01720 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
JEDFLAMM_01721 1.2e-219 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JEDFLAMM_01722 4.4e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
JEDFLAMM_01723 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
JEDFLAMM_01724 5.4e-287 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
JEDFLAMM_01725 3.8e-268 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JEDFLAMM_01726 1.9e-98 yvdD 3.2.2.10 S Belongs to the LOG family
JEDFLAMM_01727 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JEDFLAMM_01728 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JEDFLAMM_01729 8e-42 ylxQ J ribosomal protein
JEDFLAMM_01730 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
JEDFLAMM_01731 4e-199 nusA K Participates in both transcription termination and antitermination
JEDFLAMM_01732 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
JEDFLAMM_01733 2e-188 brpA K Transcriptional
JEDFLAMM_01734 2.3e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
JEDFLAMM_01735 8.5e-78 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
JEDFLAMM_01736 1.6e-247 pbuO S permease
JEDFLAMM_01737 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
JEDFLAMM_01738 5.4e-61 agrA KT LytTr DNA-binding domain
JEDFLAMM_01739 1.8e-82 blpH 2.7.13.3 T protein histidine kinase activity
JEDFLAMM_01740 6.5e-100 mesE M Transport protein ComB
JEDFLAMM_01741 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JEDFLAMM_01742 6.5e-10
JEDFLAMM_01743 1.1e-48 blpT
JEDFLAMM_01744 1.3e-23 L Transposase
JEDFLAMM_01745 3.5e-137 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
JEDFLAMM_01746 4e-168 manL 2.7.1.191 G pts system
JEDFLAMM_01747 3.4e-133 manY G pts system
JEDFLAMM_01748 6.7e-162 manN G PTS system mannose fructose sorbose family IID component
JEDFLAMM_01749 1e-66 manO S Protein conserved in bacteria
JEDFLAMM_01750 4.9e-174 manL 2.7.1.191 G pts system
JEDFLAMM_01751 2e-117 manM G pts system
JEDFLAMM_01752 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
JEDFLAMM_01753 2.5e-62 manO S protein conserved in bacteria
JEDFLAMM_01754 2.1e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JEDFLAMM_01755 2.4e-49 L COG1943 Transposase and inactivated derivatives
JEDFLAMM_01756 8.3e-111
JEDFLAMM_01757 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JEDFLAMM_01758 4.4e-166 dnaI L Primosomal protein DnaI
JEDFLAMM_01759 7.4e-214 dnaB L Replication initiation and membrane attachment
JEDFLAMM_01760 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JEDFLAMM_01761 5.9e-280 T PhoQ Sensor
JEDFLAMM_01762 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JEDFLAMM_01763 6.2e-91 yceD K metal-binding, possibly nucleic acid-binding protein
JEDFLAMM_01764 2.6e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
JEDFLAMM_01765 8e-236 P COG0168 Trk-type K transport systems, membrane components
JEDFLAMM_01766 4.8e-117 ktrA P COG0569 K transport systems, NAD-binding component
JEDFLAMM_01767 4.2e-147 cbiQ P cobalt transport
JEDFLAMM_01768 2.5e-308 ykoD P abc transporter atp-binding protein
JEDFLAMM_01769 8e-94 S UPF0397 protein
JEDFLAMM_01770 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
JEDFLAMM_01771 2.3e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JEDFLAMM_01772 1.2e-99 metI P ABC transporter (Permease
JEDFLAMM_01773 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JEDFLAMM_01774 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
JEDFLAMM_01775 3.5e-163 metQ M Belongs to the NlpA lipoprotein family
JEDFLAMM_01776 1.1e-137 ET ABC transporter substrate-binding protein
JEDFLAMM_01777 2.5e-253 S Domain of unknown function (DUF4173)
JEDFLAMM_01778 1.9e-53 yhaI L Membrane
JEDFLAMM_01779 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JEDFLAMM_01780 1.1e-153 K sequence-specific DNA binding
JEDFLAMM_01781 4.7e-101 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
JEDFLAMM_01782 2.1e-89 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JEDFLAMM_01783 8.2e-93 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JEDFLAMM_01784 2.2e-246 trkA P Potassium transporter peripheral membrane component
JEDFLAMM_01785 9e-254 trkH P Cation transport protein
JEDFLAMM_01786 1.5e-42 xylB2 2.7.1.17 G FGGY family of carbohydrate kinases, N-terminal domain
JEDFLAMM_01788 3.3e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
JEDFLAMM_01789 1.5e-104 S Domain of unknown function (DUF1803)
JEDFLAMM_01790 7.8e-102 ygaC J Belongs to the UPF0374 family
JEDFLAMM_01791 1.4e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
JEDFLAMM_01792 5.9e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JEDFLAMM_01793 2e-191 asnA 6.3.1.1 E aspartate--ammonia ligase
JEDFLAMM_01794 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JEDFLAMM_01795 1.3e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JEDFLAMM_01796 2e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JEDFLAMM_01797 1.1e-133 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
JEDFLAMM_01798 8.3e-87 ykuL S CBS domain
JEDFLAMM_01799 1.7e-98 XK27_09740 S Phosphoesterase
JEDFLAMM_01800 7.3e-183 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JEDFLAMM_01801 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JEDFLAMM_01802 1.6e-36 yneF S UPF0154 protein
JEDFLAMM_01803 1.8e-90 K transcriptional regulator
JEDFLAMM_01804 6.2e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JEDFLAMM_01805 9.3e-12 ycdA S Domain of unknown function (DUF4352)
JEDFLAMM_01806 8.5e-101 ybhL S Belongs to the BI1 family
JEDFLAMM_01807 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
JEDFLAMM_01808 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JEDFLAMM_01809 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JEDFLAMM_01810 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JEDFLAMM_01811 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JEDFLAMM_01812 7.1e-302 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JEDFLAMM_01813 1.5e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
JEDFLAMM_01814 5.2e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JEDFLAMM_01815 3.3e-23
JEDFLAMM_01816 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
JEDFLAMM_01817 1.5e-275 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
JEDFLAMM_01818 5.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JEDFLAMM_01819 9.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JEDFLAMM_01820 4e-95 ypsA S Belongs to the UPF0398 family
JEDFLAMM_01821 9.6e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JEDFLAMM_01822 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JEDFLAMM_01823 4.4e-255 pepC 3.4.22.40 E aminopeptidase
JEDFLAMM_01824 1.1e-72 yhaI S Protein of unknown function (DUF805)
JEDFLAMM_01825 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JEDFLAMM_01826 3.3e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JEDFLAMM_01827 8.6e-205 macB_2 V FtsX-like permease family
JEDFLAMM_01828 9.6e-121 yhcA V abc transporter atp-binding protein
JEDFLAMM_01829 3.1e-122 mta K Transcriptional
JEDFLAMM_01830 1.3e-30 S Protein of unknown function (DUF3021)
JEDFLAMM_01831 1.3e-73 K COG3279 Response regulator of the LytR AlgR family
JEDFLAMM_01832 2.7e-133 cylB V ABC-2 type transporter
JEDFLAMM_01833 7.8e-152 cylA V abc transporter atp-binding protein
JEDFLAMM_01834 6.3e-232 S COG1073 Hydrolases of the alpha beta superfamily
JEDFLAMM_01835 1.7e-73 K helix_turn_helix multiple antibiotic resistance protein
JEDFLAMM_01836 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JEDFLAMM_01837 1.3e-134 glcR K transcriptional regulator (DeoR family)
JEDFLAMM_01838 3.3e-144 cof S Sucrose-6F-phosphate phosphohydrolase
JEDFLAMM_01839 6.1e-68 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
JEDFLAMM_01840 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
JEDFLAMM_01841 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
JEDFLAMM_01842 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JEDFLAMM_01843 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JEDFLAMM_01844 1.1e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JEDFLAMM_01845 1.3e-54 S TM2 domain
JEDFLAMM_01846 1.9e-44
JEDFLAMM_01848 2.4e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JEDFLAMM_01849 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JEDFLAMM_01850 1.4e-142 cmpC S abc transporter atp-binding protein
JEDFLAMM_01851 0.0 WQ51_06230 S ABC transporter
JEDFLAMM_01852 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JEDFLAMM_01853 3.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
JEDFLAMM_01854 1.2e-143 cdsA 2.7.7.41 S Belongs to the CDS family
JEDFLAMM_01855 9.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JEDFLAMM_01856 5.9e-47 yajC U protein transport
JEDFLAMM_01857 6.1e-126 yeeN K transcriptional regulatory protein
JEDFLAMM_01858 1.1e-281 V ABC transporter
JEDFLAMM_01859 7.3e-150 Z012_04635 K sequence-specific DNA binding
JEDFLAMM_01860 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
JEDFLAMM_01861 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
JEDFLAMM_01862 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JEDFLAMM_01863 3.1e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
JEDFLAMM_01864 3.3e-128 adcB P ABC transporter (Permease
JEDFLAMM_01865 9.2e-135 adcC P ABC transporter, ATP-binding protein
JEDFLAMM_01866 1.3e-70 adcR K transcriptional
JEDFLAMM_01867 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JEDFLAMM_01868 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JEDFLAMM_01869 2.7e-26
JEDFLAMM_01870 2.9e-273 sufB O assembly protein SufB
JEDFLAMM_01871 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
JEDFLAMM_01872 7.2e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JEDFLAMM_01873 3.8e-232 sufD O assembly protein SufD
JEDFLAMM_01874 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JEDFLAMM_01875 3.9e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
JEDFLAMM_01876 1.2e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JEDFLAMM_01877 4.8e-18 S Protein of unknown function (DUF3021)
JEDFLAMM_01878 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JEDFLAMM_01879 2.7e-272 glnP P ABC transporter
JEDFLAMM_01880 5e-123 glnQ E abc transporter atp-binding protein
JEDFLAMM_01881 1.3e-178 D nuclear chromosome segregation
JEDFLAMM_01882 5.4e-80 V VanZ like family
JEDFLAMM_01883 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JEDFLAMM_01884 1.9e-193 yhjX P Major Facilitator
JEDFLAMM_01885 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
JEDFLAMM_01886 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JEDFLAMM_01887 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JEDFLAMM_01888 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JEDFLAMM_01889 4.4e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JEDFLAMM_01890 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JEDFLAMM_01891 5.9e-82 nrdI F Belongs to the NrdI family
JEDFLAMM_01893 8.3e-25
JEDFLAMM_01894 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
JEDFLAMM_01895 0.0 3.5.1.28 M domain protein
JEDFLAMM_01896 4.5e-132 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
JEDFLAMM_01897 5.9e-92 maa 2.3.1.79 GK Maltose O-acetyltransferase
JEDFLAMM_01898 4e-66 rmaI K Transcriptional regulator, MarR family
JEDFLAMM_01899 7.4e-237 EGP Major facilitator Superfamily
JEDFLAMM_01900 3.2e-133 XK27_00785 S CAAX protease self-immunity
JEDFLAMM_01901 0.0 zmpB M signal peptide protein, YSIRK family
JEDFLAMM_01902 0.0 GM domain, Protein
JEDFLAMM_01903 9.6e-217 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JEDFLAMM_01904 0.0 sbcC L ATPase involved in DNA repair
JEDFLAMM_01905 0.0 M family 8
JEDFLAMM_01906 1.6e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
JEDFLAMM_01907 4.7e-288 asp1 S Accessory Sec system protein Asp1
JEDFLAMM_01908 7e-289 asp2 3.4.11.5 S Accessory Sec system protein Asp2
JEDFLAMM_01909 2.5e-77 asp3 S Accessory Sec system protein Asp3
JEDFLAMM_01910 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JEDFLAMM_01911 8.5e-279 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
JEDFLAMM_01912 7.9e-244 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
JEDFLAMM_01913 2.6e-17 S Accessory secretory protein Sec Asp4
JEDFLAMM_01914 3.6e-16 S Accessory secretory protein Sec, Asp5
JEDFLAMM_01915 6.4e-190 nss M transferase activity, transferring glycosyl groups
JEDFLAMM_01916 1.1e-153 endA F DNA RNA non-specific endonuclease
JEDFLAMM_01917 2.1e-25 epuA S DNA-directed RNA polymerase subunit beta
JEDFLAMM_01918 6.5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JEDFLAMM_01919 3.7e-11 S Protein of unknown function (DUF1146)
JEDFLAMM_01920 4.3e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JEDFLAMM_01921 2e-133 G Domain of unknown function (DUF4832)
JEDFLAMM_01922 9.2e-84 S membrane
JEDFLAMM_01923 3e-96 P VTC domain
JEDFLAMM_01924 1.7e-222 cotH M CotH kinase protein
JEDFLAMM_01925 5.4e-182 pelG M Putative exopolysaccharide Exporter (EPS-E)
JEDFLAMM_01926 2.3e-270 pelF GT4 M Domain of unknown function (DUF3492)
JEDFLAMM_01927 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
JEDFLAMM_01928 2.7e-147
JEDFLAMM_01929 6.7e-275 5.1.3.2 GM Psort location CytoplasmicMembrane, score
JEDFLAMM_01930 4.6e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JEDFLAMM_01931 2.5e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JEDFLAMM_01932 3.2e-303 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JEDFLAMM_01933 6.7e-87 ytsP 1.8.4.14 T GAF domain-containing protein
JEDFLAMM_01934 2.3e-162 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JEDFLAMM_01935 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
JEDFLAMM_01938 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JEDFLAMM_01939 7.8e-214 XK27_05110 P Chloride transporter ClC family
JEDFLAMM_01940 2e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
JEDFLAMM_01941 8.3e-282 clcA P Chloride transporter, ClC family
JEDFLAMM_01942 1e-75 fld C Flavodoxin
JEDFLAMM_01943 1.1e-17 XK27_08880
JEDFLAMM_01944 1.4e-125 XK27_08875 O Zinc-dependent metalloprotease
JEDFLAMM_01945 8.6e-150 estA CE1 S Esterase
JEDFLAMM_01946 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JEDFLAMM_01947 3.1e-136 XK27_08845 S abc transporter atp-binding protein
JEDFLAMM_01948 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
JEDFLAMM_01949 3.1e-176 XK27_08835 S ABC transporter substrate binding protein
JEDFLAMM_01950 1.3e-18 S Domain of unknown function (DUF4649)
JEDFLAMM_01951 1.7e-157 Q the current gene model (or a revised gene model) may contain a frame shift
JEDFLAMM_01952 3.3e-71 M Pilin isopeptide linkage domain protein
JEDFLAMM_01954 9.2e-09
JEDFLAMM_01955 4.9e-60 cbpA O DnaJ molecular chaperone homology domain
JEDFLAMM_01956 1.9e-28

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)