ORF_ID e_value Gene_name EC_number CAZy COGs Description
KGNHNLKD_00002 6e-288 GT2,GT4 M family 8
KGNHNLKD_00003 4.5e-243 M family 8
KGNHNLKD_00004 1.3e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KGNHNLKD_00005 1.4e-222 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KGNHNLKD_00006 3.2e-220 S Psort location CytoplasmicMembrane, score
KGNHNLKD_00007 5.1e-44 S Psort location CytoplasmicMembrane, score
KGNHNLKD_00008 6.8e-164 yueF S AI-2E family transporter
KGNHNLKD_00009 2.3e-92 S dextransucrase activity
KGNHNLKD_00010 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KGNHNLKD_00011 5e-151 endA V DNA/RNA non-specific endonuclease
KGNHNLKD_00012 2.3e-254 yifK E Amino acid permease
KGNHNLKD_00014 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KGNHNLKD_00015 2.7e-230 N Uncharacterized conserved protein (DUF2075)
KGNHNLKD_00016 6.7e-122 S SNARE associated Golgi protein
KGNHNLKD_00017 0.0 uvrA3 L excinuclease ABC, A subunit
KGNHNLKD_00018 1.7e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KGNHNLKD_00019 1.1e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KGNHNLKD_00020 4.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KGNHNLKD_00021 2.7e-138 S DUF218 domain
KGNHNLKD_00022 0.0 ubiB S ABC1 family
KGNHNLKD_00023 2.1e-244 yhdP S Transporter associated domain
KGNHNLKD_00024 5e-75 copY K Copper transport repressor CopY TcrY
KGNHNLKD_00025 8.7e-246 EGP Major facilitator Superfamily
KGNHNLKD_00026 4.5e-74 yeaL S UPF0756 membrane protein
KGNHNLKD_00027 1.2e-78 yphH S Cupin domain
KGNHNLKD_00028 1.1e-62 K Transcriptional regulator
KGNHNLKD_00029 4e-167 1.1.1.346 C Aldo keto reductase
KGNHNLKD_00030 3.4e-17 gcvR T Belongs to the UPF0237 family
KGNHNLKD_00031 6.3e-82 XK27_08635 S UPF0210 protein
KGNHNLKD_00032 3.6e-149 XK27_08635 S UPF0210 protein
KGNHNLKD_00033 1.8e-95 K Acetyltransferase (GNAT) domain
KGNHNLKD_00034 1.2e-160 S Alpha beta hydrolase
KGNHNLKD_00035 8.7e-110 gspA M family 8
KGNHNLKD_00036 1.7e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KGNHNLKD_00037 9.4e-94
KGNHNLKD_00038 6.4e-162 degV S EDD domain protein, DegV family
KGNHNLKD_00039 0.0 FbpA K Fibronectin-binding protein
KGNHNLKD_00040 5.9e-214 uhpT EGP Major facilitator Superfamily
KGNHNLKD_00041 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
KGNHNLKD_00042 1e-129 ponA V Beta-lactamase enzyme family
KGNHNLKD_00043 3.1e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KGNHNLKD_00044 4.3e-74
KGNHNLKD_00045 7e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KGNHNLKD_00046 8.1e-28
KGNHNLKD_00047 7.6e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
KGNHNLKD_00048 9.5e-294 L PFAM plasmid pRiA4b ORF-3 family protein
KGNHNLKD_00049 4.3e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
KGNHNLKD_00050 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KGNHNLKD_00051 3.2e-161 mleR K LysR family
KGNHNLKD_00052 7.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KGNHNLKD_00053 1.8e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KGNHNLKD_00054 5.3e-267 frdC 1.3.5.4 C FAD binding domain
KGNHNLKD_00055 3.1e-130 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KGNHNLKD_00056 1e-164 citP P Sodium:sulfate symporter transmembrane region
KGNHNLKD_00057 1.8e-125 citR K sugar-binding domain protein
KGNHNLKD_00058 4.6e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
KGNHNLKD_00059 5.7e-149 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KGNHNLKD_00060 7.9e-40 citD C Covalent carrier of the coenzyme of citrate lyase
KGNHNLKD_00061 5.3e-159 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
KGNHNLKD_00062 1e-271 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
KGNHNLKD_00063 1e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KGNHNLKD_00064 4.2e-112 ydjP I Alpha/beta hydrolase family
KGNHNLKD_00065 8.2e-157 mleR K LysR family
KGNHNLKD_00066 2.3e-251 yjjP S Putative threonine/serine exporter
KGNHNLKD_00067 9.5e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
KGNHNLKD_00068 1e-271 emrY EGP Major facilitator Superfamily
KGNHNLKD_00069 3.3e-183 I Alpha beta
KGNHNLKD_00070 1.2e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KGNHNLKD_00071 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KGNHNLKD_00073 1.2e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KGNHNLKD_00074 1e-120 S Domain of unknown function (DUF4811)
KGNHNLKD_00075 4.7e-269 lmrB EGP Major facilitator Superfamily
KGNHNLKD_00076 2.8e-73 merR K MerR HTH family regulatory protein
KGNHNLKD_00077 7.2e-56
KGNHNLKD_00078 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KGNHNLKD_00079 4e-215 S CAAX protease self-immunity
KGNHNLKD_00080 3.6e-109 glnP P ABC transporter permease
KGNHNLKD_00081 3.2e-110 gluC P ABC transporter permease
KGNHNLKD_00082 2.2e-151 glnH ET ABC transporter
KGNHNLKD_00083 5.3e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KGNHNLKD_00084 5.5e-83 usp1 T Belongs to the universal stress protein A family
KGNHNLKD_00085 7.6e-110 S VIT family
KGNHNLKD_00086 1.7e-117 S membrane
KGNHNLKD_00087 3.5e-166 czcD P cation diffusion facilitator family transporter
KGNHNLKD_00088 2e-123 sirR K iron dependent repressor
KGNHNLKD_00089 7.9e-31 cspC K Cold shock protein
KGNHNLKD_00090 2.1e-129 thrE S Putative threonine/serine exporter
KGNHNLKD_00091 2.1e-82 S Threonine/Serine exporter, ThrE
KGNHNLKD_00092 2.3e-119 lssY 3.6.1.27 I phosphatase
KGNHNLKD_00093 4.5e-11 2.3.1.128 J Acetyltransferase (GNAT) domain
KGNHNLKD_00094 1.1e-275 lysP E amino acid
KGNHNLKD_00095 5.6e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KGNHNLKD_00101 4.7e-12
KGNHNLKD_00102 1.7e-179 S Hydrolases of the alpha beta superfamily
KGNHNLKD_00103 2.7e-196 adhP 1.1.1.1 C alcohol dehydrogenase
KGNHNLKD_00104 4.4e-77 ctsR K Belongs to the CtsR family
KGNHNLKD_00105 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KGNHNLKD_00106 1e-110 K Bacterial regulatory proteins, tetR family
KGNHNLKD_00107 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGNHNLKD_00108 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGNHNLKD_00109 1.6e-203 ykiI
KGNHNLKD_00110 5.7e-118 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
KGNHNLKD_00111 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KGNHNLKD_00112 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KGNHNLKD_00113 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KGNHNLKD_00114 1.4e-125 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KGNHNLKD_00115 1.9e-30 L Transposase
KGNHNLKD_00116 2.2e-145 holA 2.7.7.7 L DNA polymerase III delta subunit
KGNHNLKD_00117 0.0 comEC S Competence protein ComEC
KGNHNLKD_00118 2.6e-88 comEB 3.5.4.12 F ComE operon protein 2
KGNHNLKD_00119 8.3e-79 comEA L Competence protein ComEA
KGNHNLKD_00120 2.1e-199 ylbL T Belongs to the peptidase S16 family
KGNHNLKD_00121 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KGNHNLKD_00122 1.2e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KGNHNLKD_00123 1.5e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KGNHNLKD_00124 1.1e-223 ftsW D Belongs to the SEDS family
KGNHNLKD_00125 0.0 typA T GTP-binding protein TypA
KGNHNLKD_00126 1e-134 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KGNHNLKD_00127 1.4e-47 yktA S Belongs to the UPF0223 family
KGNHNLKD_00128 5.4e-275 lpdA 1.8.1.4 C Dehydrogenase
KGNHNLKD_00129 3e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KGNHNLKD_00130 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
KGNHNLKD_00131 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KGNHNLKD_00132 3.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KGNHNLKD_00133 4.4e-80
KGNHNLKD_00134 9.8e-32 ykzG S Belongs to the UPF0356 family
KGNHNLKD_00135 1.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
KGNHNLKD_00136 3.7e-28
KGNHNLKD_00137 3.6e-125 mltD CBM50 M NlpC P60 family protein
KGNHNLKD_00139 7.7e-58
KGNHNLKD_00140 2.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KGNHNLKD_00141 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KGNHNLKD_00142 3.8e-218 patA 2.6.1.1 E Aminotransferase
KGNHNLKD_00143 5e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KGNHNLKD_00144 5.3e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KGNHNLKD_00145 2.1e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KGNHNLKD_00146 1.7e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KGNHNLKD_00147 9.4e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KGNHNLKD_00148 1.1e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
KGNHNLKD_00149 3e-187 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KGNHNLKD_00150 1.2e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KGNHNLKD_00151 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KGNHNLKD_00152 9.9e-118 S Repeat protein
KGNHNLKD_00153 3.7e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
KGNHNLKD_00154 1.3e-223 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KGNHNLKD_00155 2.8e-57 XK27_04120 S Putative amino acid metabolism
KGNHNLKD_00156 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
KGNHNLKD_00157 6.5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KGNHNLKD_00159 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KGNHNLKD_00160 4.2e-32 cspA K Cold shock protein
KGNHNLKD_00161 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KGNHNLKD_00162 1.9e-42 divIVA D DivIVA domain protein
KGNHNLKD_00163 1.7e-142 ylmH S S4 domain protein
KGNHNLKD_00164 3.2e-40 yggT S YGGT family
KGNHNLKD_00165 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KGNHNLKD_00166 1.5e-225 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KGNHNLKD_00167 1.6e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KGNHNLKD_00168 1.3e-140 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KGNHNLKD_00169 7.3e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KGNHNLKD_00170 2.9e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KGNHNLKD_00171 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KGNHNLKD_00172 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KGNHNLKD_00173 1.5e-56 ftsL D Cell division protein FtsL
KGNHNLKD_00174 6.1e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KGNHNLKD_00175 3.1e-77 mraZ K Belongs to the MraZ family
KGNHNLKD_00176 2.7e-200 pbuG S permease
KGNHNLKD_00177 6.7e-270 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
KGNHNLKD_00178 2.6e-184 gadC E amino acid
KGNHNLKD_00179 8.5e-97 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KGNHNLKD_00180 9.2e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KGNHNLKD_00181 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KGNHNLKD_00182 1.5e-138 S Belongs to the UPF0246 family
KGNHNLKD_00183 1.2e-137 S Membrane
KGNHNLKD_00184 8.1e-75 4.4.1.5 E Glyoxalase
KGNHNLKD_00185 1.2e-21
KGNHNLKD_00186 3.8e-87 yueI S Protein of unknown function (DUF1694)
KGNHNLKD_00187 1e-235 rarA L recombination factor protein RarA
KGNHNLKD_00188 5.7e-46
KGNHNLKD_00189 4.3e-83 usp6 T universal stress protein
KGNHNLKD_00190 5.9e-205 araR K Transcriptional regulator
KGNHNLKD_00191 1.9e-155 ytbE 1.1.1.346 S Aldo keto reductase
KGNHNLKD_00192 1e-91 maa 2.3.1.79 S Maltose O-acetyltransferase
KGNHNLKD_00193 3.1e-283 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KGNHNLKD_00194 1.6e-137 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KGNHNLKD_00195 0.0 araB 2.7.1.16 G carbohydrate kinase FGGY
KGNHNLKD_00196 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KGNHNLKD_00197 9.2e-52 XK27_01125 L PFAM IS66 Orf2 family protein
KGNHNLKD_00198 2.4e-223 S Uncharacterised protein family (UPF0236)
KGNHNLKD_00199 5e-44
KGNHNLKD_00200 0.0 nylA 3.5.1.4 J Belongs to the amidase family
KGNHNLKD_00201 9.1e-22
KGNHNLKD_00202 5.4e-47
KGNHNLKD_00203 1.9e-95 K Acetyltransferase (GNAT) domain
KGNHNLKD_00204 2.1e-293 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KGNHNLKD_00205 2.8e-233 gntT EG Gluconate
KGNHNLKD_00206 1.2e-183 K Transcriptional regulator, LacI family
KGNHNLKD_00207 1.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KGNHNLKD_00210 2.7e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KGNHNLKD_00221 2.6e-90 L Integrase
KGNHNLKD_00222 6e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KGNHNLKD_00223 3.3e-15 K Transcriptional regulator, LacI family
KGNHNLKD_00224 8.6e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KGNHNLKD_00225 6.3e-57 yitW S Pfam:DUF59
KGNHNLKD_00226 1.6e-141 acmD M repeat protein
KGNHNLKD_00227 1.8e-195 S enterobacterial common antigen metabolic process
KGNHNLKD_00228 9.6e-194 M transferase activity, transferring glycosyl groups
KGNHNLKD_00229 9.3e-200 waaB GT4 M Glycosyl transferases group 1
KGNHNLKD_00230 3.1e-259 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
KGNHNLKD_00231 1.4e-105 M biosynthesis protein
KGNHNLKD_00232 1.6e-216 cps3F
KGNHNLKD_00233 3.9e-220 glf 5.4.99.9 M UDP-galactopyranose mutase
KGNHNLKD_00234 5.1e-116 rfbP 2.7.8.6 M Bacterial sugar transferase
KGNHNLKD_00235 8e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KGNHNLKD_00236 6.7e-147 cps1D M Domain of unknown function (DUF4422)
KGNHNLKD_00237 2.5e-141 recX 2.4.1.337 GT4 S Regulatory protein RecX
KGNHNLKD_00238 1.9e-30
KGNHNLKD_00239 1.9e-33 S Protein of unknown function (DUF2922)
KGNHNLKD_00240 1.5e-153 yihY S Belongs to the UPF0761 family
KGNHNLKD_00241 1.5e-280 yjeM E Amino Acid
KGNHNLKD_00242 1.5e-256 E Arginine ornithine antiporter
KGNHNLKD_00243 1.3e-220 arcT 2.6.1.1 E Aminotransferase
KGNHNLKD_00244 6.5e-167 map 3.4.11.18 E Methionine Aminopeptidase
KGNHNLKD_00245 3.9e-78 fld C Flavodoxin
KGNHNLKD_00246 2.3e-67 gtcA S Teichoic acid glycosylation protein
KGNHNLKD_00247 6.6e-37
KGNHNLKD_00248 9.3e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KGNHNLKD_00250 7.4e-231 yfmL L DEAD DEAH box helicase
KGNHNLKD_00251 3.8e-190 mocA S Oxidoreductase
KGNHNLKD_00252 9.1e-62 S Domain of unknown function (DUF4828)
KGNHNLKD_00253 2.3e-47 L Transposase IS66 family
KGNHNLKD_00254 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KGNHNLKD_00255 3.1e-206 carA 6.3.5.5 F Belongs to the CarA family
KGNHNLKD_00256 3.1e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KGNHNLKD_00257 7.7e-71 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KGNHNLKD_00258 1.5e-65 esbA S Family of unknown function (DUF5322)
KGNHNLKD_00259 2.6e-70 rnhA 3.1.26.4 L Ribonuclease HI
KGNHNLKD_00260 3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KGNHNLKD_00261 1.1e-83 F Belongs to the NrdI family
KGNHNLKD_00262 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KGNHNLKD_00263 1.1e-101 ypsA S Belongs to the UPF0398 family
KGNHNLKD_00264 1.2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KGNHNLKD_00265 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KGNHNLKD_00266 1.3e-160 EG EamA-like transporter family
KGNHNLKD_00267 2.8e-123 dnaD L DnaD domain protein
KGNHNLKD_00268 7.6e-86 ypmB S Protein conserved in bacteria
KGNHNLKD_00269 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KGNHNLKD_00270 5.3e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KGNHNLKD_00271 1.3e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KGNHNLKD_00272 3.9e-212 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KGNHNLKD_00273 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KGNHNLKD_00274 5.5e-217 xylR GK ROK family
KGNHNLKD_00275 8.5e-28
KGNHNLKD_00276 2.5e-261 pgi 5.3.1.9 G Belongs to the GPI family
KGNHNLKD_00277 1.7e-100 lacA 2.3.1.79 S Transferase hexapeptide repeat
KGNHNLKD_00278 2e-155 glcU U sugar transport
KGNHNLKD_00279 2.7e-269 yclK 2.7.13.3 T Histidine kinase
KGNHNLKD_00280 4.4e-132 K response regulator
KGNHNLKD_00282 1e-73 lytE M Lysin motif
KGNHNLKD_00283 4.5e-146 XK27_02985 S Cof-like hydrolase
KGNHNLKD_00284 4.3e-80 K Transcriptional regulator
KGNHNLKD_00285 0.0 oatA I Acyltransferase
KGNHNLKD_00286 8.7e-53
KGNHNLKD_00287 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KGNHNLKD_00288 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KGNHNLKD_00289 7.6e-126 ybbR S YbbR-like protein
KGNHNLKD_00290 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KGNHNLKD_00291 4.6e-233 fucP G Major Facilitator Superfamily
KGNHNLKD_00292 2.1e-177 M Glycosyltransferase like family 2
KGNHNLKD_00293 3e-27
KGNHNLKD_00294 3e-71 M repeat protein
KGNHNLKD_00295 0.0 lacZ 3.2.1.23 G -beta-galactosidase
KGNHNLKD_00296 0.0 lacS G Transporter
KGNHNLKD_00297 4.4e-186 lacR K Transcriptional regulator
KGNHNLKD_00298 6.2e-41 L hmm pf00665
KGNHNLKD_00299 5e-57
KGNHNLKD_00300 1.2e-10 S Protein of unknown function (DUF4044)
KGNHNLKD_00301 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KGNHNLKD_00302 2.2e-93 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KGNHNLKD_00303 2.9e-159 rrmA 2.1.1.187 H Methyltransferase
KGNHNLKD_00304 7.8e-183 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KGNHNLKD_00305 4.1e-71
KGNHNLKD_00306 7.9e-264 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KGNHNLKD_00307 9.4e-262 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
KGNHNLKD_00308 8e-268 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
KGNHNLKD_00309 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KGNHNLKD_00310 8.2e-162 G Major Facilitator
KGNHNLKD_00311 1.3e-54 G Major Facilitator
KGNHNLKD_00312 1.8e-259 G Major Facilitator
KGNHNLKD_00313 1.3e-182 K Transcriptional regulator, LacI family
KGNHNLKD_00314 4.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KGNHNLKD_00315 5.4e-101 nqr 1.5.1.36 S reductase
KGNHNLKD_00316 6.7e-197 XK27_09615 S reductase
KGNHNLKD_00317 1.7e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KGNHNLKD_00318 1.5e-121 K response regulator
KGNHNLKD_00319 4.5e-277 arlS 2.7.13.3 T Histidine kinase
KGNHNLKD_00320 1.8e-268 yjeM E Amino Acid
KGNHNLKD_00321 1.5e-231 V MatE
KGNHNLKD_00322 2.5e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KGNHNLKD_00323 9.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KGNHNLKD_00324 7.2e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KGNHNLKD_00325 1.4e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KGNHNLKD_00326 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KGNHNLKD_00327 6.7e-59 yodB K Transcriptional regulator, HxlR family
KGNHNLKD_00328 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KGNHNLKD_00329 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KGNHNLKD_00330 1.2e-114 rlpA M PFAM NLP P60 protein
KGNHNLKD_00331 7.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
KGNHNLKD_00332 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KGNHNLKD_00333 1.3e-69 yneR S Belongs to the HesB IscA family
KGNHNLKD_00334 0.0 S membrane
KGNHNLKD_00335 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KGNHNLKD_00336 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KGNHNLKD_00337 1.3e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KGNHNLKD_00338 2.4e-113 gluP 3.4.21.105 S Peptidase, S54 family
KGNHNLKD_00339 2.1e-32 yqgQ S Bacterial protein of unknown function (DUF910)
KGNHNLKD_00340 1.5e-183 glk 2.7.1.2 G Glucokinase
KGNHNLKD_00341 2.6e-67 yqhL P Rhodanese-like protein
KGNHNLKD_00342 5.9e-22 S Protein of unknown function (DUF3042)
KGNHNLKD_00343 1.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KGNHNLKD_00344 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
KGNHNLKD_00345 1.3e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KGNHNLKD_00346 1.6e-224 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KGNHNLKD_00347 3.9e-12
KGNHNLKD_00348 8.7e-156 P Belongs to the nlpA lipoprotein family
KGNHNLKD_00349 2.5e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KGNHNLKD_00350 8.2e-51 S Iron-sulfur cluster assembly protein
KGNHNLKD_00351 2e-147
KGNHNLKD_00352 5.9e-175
KGNHNLKD_00353 1.9e-86 dut S Protein conserved in bacteria
KGNHNLKD_00356 5.8e-112 K Transcriptional regulator
KGNHNLKD_00357 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
KGNHNLKD_00358 1.6e-54 ysxB J Cysteine protease Prp
KGNHNLKD_00359 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KGNHNLKD_00360 3.2e-127 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KGNHNLKD_00361 3.1e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KGNHNLKD_00362 8.9e-111 J 2'-5' RNA ligase superfamily
KGNHNLKD_00363 2.2e-70 yqhY S Asp23 family, cell envelope-related function
KGNHNLKD_00364 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KGNHNLKD_00365 1.2e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KGNHNLKD_00366 3.8e-222 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KGNHNLKD_00367 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KGNHNLKD_00368 2.2e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KGNHNLKD_00369 4.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KGNHNLKD_00370 8.7e-78 argR K Regulates arginine biosynthesis genes
KGNHNLKD_00371 8.9e-261 recN L May be involved in recombinational repair of damaged DNA
KGNHNLKD_00372 4.9e-54
KGNHNLKD_00373 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KGNHNLKD_00374 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KGNHNLKD_00375 9.3e-212 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KGNHNLKD_00376 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KGNHNLKD_00377 3.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KGNHNLKD_00378 2.2e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KGNHNLKD_00379 3.8e-131 stp 3.1.3.16 T phosphatase
KGNHNLKD_00380 0.0 KLT serine threonine protein kinase
KGNHNLKD_00381 2.7e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KGNHNLKD_00382 1.4e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KGNHNLKD_00383 4.8e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
KGNHNLKD_00384 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KGNHNLKD_00385 4.7e-58 asp S Asp23 family, cell envelope-related function
KGNHNLKD_00386 0.0 yloV S DAK2 domain fusion protein YloV
KGNHNLKD_00387 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KGNHNLKD_00388 4.9e-185 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KGNHNLKD_00389 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KGNHNLKD_00390 1.2e-131 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KGNHNLKD_00391 0.0 smc D Required for chromosome condensation and partitioning
KGNHNLKD_00392 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KGNHNLKD_00393 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KGNHNLKD_00394 1.3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KGNHNLKD_00395 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KGNHNLKD_00396 2.7e-39 ylqC S Belongs to the UPF0109 family
KGNHNLKD_00397 3.8e-90 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KGNHNLKD_00398 4.1e-141 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KGNHNLKD_00399 4.4e-261 yfnA E amino acid
KGNHNLKD_00400 7.3e-138 IQ KR domain
KGNHNLKD_00401 3.1e-40 fhaB M Rib/alpha-like repeat
KGNHNLKD_00402 1.9e-21 P Belongs to the ABC transporter superfamily
KGNHNLKD_00403 5.7e-56 EP N-terminal TM domain of oligopeptide transport permease C
KGNHNLKD_00404 1e-48 nikB P Binding-protein-dependent transport system inner membrane component
KGNHNLKD_00405 8.1e-55 nikA E Nickel ABC transporter
KGNHNLKD_00406 1.2e-89 nikA E Bacterial extracellular solute-binding proteins, family 5 Middle
KGNHNLKD_00407 1.3e-57 ubiE_1 Q Methyltransferase
KGNHNLKD_00408 2.9e-254 ytjP 3.5.1.18 E Dipeptidase
KGNHNLKD_00409 2e-272 arcD S C4-dicarboxylate anaerobic carrier
KGNHNLKD_00410 6.7e-173 yfeX P Peroxidase
KGNHNLKD_00411 2.4e-126 lsa S ABC transporter
KGNHNLKD_00412 5.5e-111 I alpha/beta hydrolase fold
KGNHNLKD_00413 1.2e-172 MA20_14895 S Conserved hypothetical protein 698
KGNHNLKD_00414 1.5e-84 S NADPH-dependent FMN reductase
KGNHNLKD_00415 5.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KGNHNLKD_00416 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KGNHNLKD_00417 1.8e-232 mntH P H( )-stimulated, divalent metal cation uptake system
KGNHNLKD_00418 3.8e-80 Q Methyltransferase
KGNHNLKD_00419 6.9e-116 ktrA P domain protein
KGNHNLKD_00420 5.8e-239 ktrB P Potassium uptake protein
KGNHNLKD_00421 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KGNHNLKD_00422 6.6e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KGNHNLKD_00423 1.1e-222 G Glycosyl hydrolases family 8
KGNHNLKD_00424 2.7e-241 ydaM M Glycosyl transferase
KGNHNLKD_00425 6.6e-135
KGNHNLKD_00426 1.2e-46 L Transposase IS66 family
KGNHNLKD_00427 1.6e-109 dedA S SNARE-like domain protein
KGNHNLKD_00428 4.1e-113 S Protein of unknown function (DUF1461)
KGNHNLKD_00429 5.1e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KGNHNLKD_00430 4.8e-99 yutD S Protein of unknown function (DUF1027)
KGNHNLKD_00431 7e-115 S Calcineurin-like phosphoesterase
KGNHNLKD_00432 3.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KGNHNLKD_00433 1.3e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
KGNHNLKD_00434 2.4e-69
KGNHNLKD_00435 7.1e-41
KGNHNLKD_00436 1.4e-77 NU general secretion pathway protein
KGNHNLKD_00437 1.2e-46 comGC U competence protein ComGC
KGNHNLKD_00438 2.3e-182 comGB NU type II secretion system
KGNHNLKD_00439 4.3e-183 comGA NU Type II IV secretion system protein
KGNHNLKD_00440 1e-131 yebC K Transcriptional regulatory protein
KGNHNLKD_00441 2.5e-134
KGNHNLKD_00442 4.5e-183 ccpA K catabolite control protein A
KGNHNLKD_00443 9.4e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KGNHNLKD_00444 2.6e-13
KGNHNLKD_00445 1.2e-36 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KGNHNLKD_00446 4e-148 ykuT M mechanosensitive ion channel
KGNHNLKD_00447 1e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
KGNHNLKD_00448 3.6e-76 ykuL S (CBS) domain
KGNHNLKD_00449 5.3e-95 S Phosphoesterase
KGNHNLKD_00450 2.4e-104 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KGNHNLKD_00451 8.5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KGNHNLKD_00452 3.9e-96 yslB S Protein of unknown function (DUF2507)
KGNHNLKD_00453 6.1e-54 trxA O Belongs to the thioredoxin family
KGNHNLKD_00454 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KGNHNLKD_00455 5.1e-85 cvpA S Colicin V production protein
KGNHNLKD_00456 5.2e-47 yrzB S Belongs to the UPF0473 family
KGNHNLKD_00457 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KGNHNLKD_00458 1.2e-42 yrzL S Belongs to the UPF0297 family
KGNHNLKD_00459 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KGNHNLKD_00460 1.4e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KGNHNLKD_00461 5.5e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KGNHNLKD_00462 2.7e-31 yajC U Preprotein translocase
KGNHNLKD_00463 1e-196 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KGNHNLKD_00464 5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KGNHNLKD_00465 6.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KGNHNLKD_00466 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KGNHNLKD_00467 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KGNHNLKD_00468 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
KGNHNLKD_00469 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KGNHNLKD_00470 6.6e-229 cinA 3.5.1.42 S Belongs to the CinA family
KGNHNLKD_00471 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KGNHNLKD_00472 1.4e-139 ymfM S Helix-turn-helix domain
KGNHNLKD_00473 1.8e-248 ymfH S Peptidase M16
KGNHNLKD_00474 6.6e-229 ymfF S Peptidase M16 inactive domain protein
KGNHNLKD_00475 2.6e-160 aatB ET ABC transporter substrate-binding protein
KGNHNLKD_00476 1.4e-116 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KGNHNLKD_00477 3.2e-102 glnP P ABC transporter permease
KGNHNLKD_00478 3.3e-92 mreD M rod shape-determining protein MreD
KGNHNLKD_00479 7.7e-152 mreC M Involved in formation and maintenance of cell shape
KGNHNLKD_00480 1.7e-179 mreB D cell shape determining protein MreB
KGNHNLKD_00481 2e-120 radC L DNA repair protein
KGNHNLKD_00482 9.7e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KGNHNLKD_00483 4.5e-230 ndh 1.6.99.3 C NADH dehydrogenase
KGNHNLKD_00484 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KGNHNLKD_00485 2.2e-307 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KGNHNLKD_00486 9e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KGNHNLKD_00487 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
KGNHNLKD_00488 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KGNHNLKD_00489 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KGNHNLKD_00490 1.7e-215 iscS2 2.8.1.7 E Aminotransferase class V
KGNHNLKD_00491 6.5e-251 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KGNHNLKD_00492 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KGNHNLKD_00503 9.1e-187 L Transposase
KGNHNLKD_00504 8.6e-63 L Helix-turn-helix domain
KGNHNLKD_00505 5e-153 L PFAM Integrase catalytic region
KGNHNLKD_00507 4.5e-112 ywnB S NAD(P)H-binding
KGNHNLKD_00508 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
KGNHNLKD_00509 1.9e-256 nhaC C Na H antiporter NhaC
KGNHNLKD_00510 5.4e-184 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KGNHNLKD_00512 4.6e-102 ydeN S Serine hydrolase
KGNHNLKD_00513 2.9e-61 psiE S Phosphate-starvation-inducible E
KGNHNLKD_00514 1.6e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KGNHNLKD_00516 1.1e-180 S Aldo keto reductase
KGNHNLKD_00517 2.9e-82 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
KGNHNLKD_00518 0.0 L Helicase C-terminal domain protein
KGNHNLKD_00520 4.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KGNHNLKD_00521 4.7e-54 S Sugar efflux transporter for intercellular exchange
KGNHNLKD_00522 1.1e-124
KGNHNLKD_00523 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KGNHNLKD_00524 3e-307 cadA P P-type ATPase
KGNHNLKD_00525 4.7e-208 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KGNHNLKD_00526 6.2e-76 K Transcriptional regulator
KGNHNLKD_00527 6e-163 proX M ABC transporter, substrate-binding protein, QAT family
KGNHNLKD_00528 8.2e-109 proWZ P ABC transporter permease
KGNHNLKD_00529 9.4e-141 proV E ABC transporter, ATP-binding protein
KGNHNLKD_00530 2.3e-100 proW P ABC transporter, permease protein
KGNHNLKD_00531 2.8e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KGNHNLKD_00532 3.9e-187 clcA P chloride
KGNHNLKD_00533 2.2e-28 clcA P chloride
KGNHNLKD_00534 1.2e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KGNHNLKD_00535 4.1e-103 metI P ABC transporter permease
KGNHNLKD_00536 6.8e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KGNHNLKD_00537 6.7e-156 metQ1 P Belongs to the nlpA lipoprotein family
KGNHNLKD_00538 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KGNHNLKD_00539 1.1e-220 norA EGP Major facilitator Superfamily
KGNHNLKD_00540 4e-41 1.3.5.4 S FMN binding
KGNHNLKD_00541 6e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KGNHNLKD_00542 2.1e-266 yfnA E amino acid
KGNHNLKD_00543 1.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KGNHNLKD_00545 4.1e-54 L Transposase, IS116 IS110 IS902 family
KGNHNLKD_00546 1.9e-197 clcA P chloride
KGNHNLKD_00547 1.3e-202 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KGNHNLKD_00548 0.0 helD 3.6.4.12 L DNA helicase
KGNHNLKD_00549 8.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
KGNHNLKD_00550 4.8e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KGNHNLKD_00551 7.7e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KGNHNLKD_00552 1.8e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KGNHNLKD_00553 3.1e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KGNHNLKD_00554 1.9e-175
KGNHNLKD_00555 6.8e-130 cobB K SIR2 family
KGNHNLKD_00557 4.8e-162 yunF F Protein of unknown function DUF72
KGNHNLKD_00558 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KGNHNLKD_00559 2.4e-155 tatD L hydrolase, TatD family
KGNHNLKD_00560 3.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KGNHNLKD_00561 3.8e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KGNHNLKD_00562 6.8e-37 veg S Biofilm formation stimulator VEG
KGNHNLKD_00563 7.6e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KGNHNLKD_00564 3.3e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
KGNHNLKD_00565 3.8e-122 fhuC P ABC transporter
KGNHNLKD_00566 4.7e-119 znuB U ABC 3 transport family
KGNHNLKD_00567 2.6e-149 purR 2.4.2.7 F pur operon repressor
KGNHNLKD_00568 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KGNHNLKD_00569 3.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KGNHNLKD_00570 2.6e-47
KGNHNLKD_00571 8.4e-148 yxeH S hydrolase
KGNHNLKD_00572 3.8e-270 ywfO S HD domain protein
KGNHNLKD_00573 3.9e-145 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
KGNHNLKD_00574 1.1e-65 ywiB S Domain of unknown function (DUF1934)
KGNHNLKD_00575 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KGNHNLKD_00576 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KGNHNLKD_00577 4.9e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KGNHNLKD_00578 4.6e-41 rpmE2 J Ribosomal protein L31
KGNHNLKD_00579 1.7e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KGNHNLKD_00580 3.3e-166 S Alpha/beta hydrolase of unknown function (DUF915)
KGNHNLKD_00581 1.1e-124 srtA 3.4.22.70 M sortase family
KGNHNLKD_00582 5.8e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KGNHNLKD_00583 1.7e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KGNHNLKD_00584 7.8e-120 pgm3 G Belongs to the phosphoglycerate mutase family
KGNHNLKD_00585 2.3e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KGNHNLKD_00586 2e-92 lemA S LemA family
KGNHNLKD_00587 1.5e-158 htpX O Belongs to the peptidase M48B family
KGNHNLKD_00588 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KGNHNLKD_00589 5.3e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KGNHNLKD_00590 0.0 sprD D Domain of Unknown Function (DUF1542)
KGNHNLKD_00591 7.7e-166 glsA 3.5.1.2 E Belongs to the glutaminase family
KGNHNLKD_00592 3.4e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KGNHNLKD_00593 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGNHNLKD_00594 4.3e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
KGNHNLKD_00595 7.2e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KGNHNLKD_00597 2.6e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KGNHNLKD_00598 6.2e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KGNHNLKD_00599 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
KGNHNLKD_00600 1.2e-250 U Belongs to the purine-cytosine permease (2.A.39) family
KGNHNLKD_00601 8.3e-240 codA 3.5.4.1 F cytosine deaminase
KGNHNLKD_00602 2e-146 tesE Q hydratase
KGNHNLKD_00603 6.9e-113 S (CBS) domain
KGNHNLKD_00604 2.1e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KGNHNLKD_00605 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KGNHNLKD_00606 2.1e-39 yabO J S4 domain protein
KGNHNLKD_00607 6.6e-57 divIC D Septum formation initiator
KGNHNLKD_00608 9.8e-67 yabR J RNA binding
KGNHNLKD_00609 7.2e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KGNHNLKD_00610 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KGNHNLKD_00611 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KGNHNLKD_00612 5.2e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KGNHNLKD_00613 5.4e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KGNHNLKD_00614 6.1e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KGNHNLKD_00615 1.2e-282 O Arylsulfotransferase (ASST)
KGNHNLKD_00616 1.1e-56 K transcriptional regulator PadR family
KGNHNLKD_00617 4.9e-84 XK27_06920 S Protein of unknown function (DUF1700)
KGNHNLKD_00618 1.8e-136 S Putative adhesin
KGNHNLKD_00619 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KGNHNLKD_00620 2.9e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KGNHNLKD_00621 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KGNHNLKD_00622 3.4e-35 nrdH O Glutaredoxin
KGNHNLKD_00623 7.7e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KGNHNLKD_00624 7.1e-288 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KGNHNLKD_00625 4.6e-46 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KGNHNLKD_00626 4.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KGNHNLKD_00627 9.7e-39 S Protein of unknown function (DUF2508)
KGNHNLKD_00628 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KGNHNLKD_00629 7.6e-52 yaaQ S Cyclic-di-AMP receptor
KGNHNLKD_00630 1.2e-183 holB 2.7.7.7 L DNA polymerase III
KGNHNLKD_00631 5.9e-58 yabA L Involved in initiation control of chromosome replication
KGNHNLKD_00632 3.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KGNHNLKD_00633 8.1e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
KGNHNLKD_00634 1.3e-279 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KGNHNLKD_00635 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KGNHNLKD_00636 1.3e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KGNHNLKD_00637 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KGNHNLKD_00638 3.6e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KGNHNLKD_00639 4.7e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KGNHNLKD_00640 1.9e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KGNHNLKD_00644 1.5e-48
KGNHNLKD_00645 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KGNHNLKD_00646 3.8e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KGNHNLKD_00647 5.8e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KGNHNLKD_00648 1.9e-247 M Glycosyl transferase family group 2
KGNHNLKD_00650 1.1e-223 aadAT EK Aminotransferase, class I
KGNHNLKD_00651 2.8e-30 S Predicted membrane protein (DUF2207)
KGNHNLKD_00652 6.7e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KGNHNLKD_00653 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KGNHNLKD_00654 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
KGNHNLKD_00655 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KGNHNLKD_00656 2.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KGNHNLKD_00657 9.4e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KGNHNLKD_00658 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KGNHNLKD_00659 2.3e-207 yacL S domain protein
KGNHNLKD_00660 3.9e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KGNHNLKD_00661 3.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KGNHNLKD_00662 1.9e-49 HA62_12640 S GCN5-related N-acetyl-transferase
KGNHNLKD_00663 5.8e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KGNHNLKD_00664 6.2e-265 pepC 3.4.22.40 E Peptidase C1-like family
KGNHNLKD_00665 2.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KGNHNLKD_00666 4.5e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KGNHNLKD_00667 1.4e-119 tcyB E ABC transporter
KGNHNLKD_00668 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KGNHNLKD_00669 9.2e-169 I alpha/beta hydrolase fold
KGNHNLKD_00670 1.3e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KGNHNLKD_00671 0.0 S Bacterial membrane protein, YfhO
KGNHNLKD_00672 7.2e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KGNHNLKD_00673 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KGNHNLKD_00675 1.8e-83 ydcK S Belongs to the SprT family
KGNHNLKD_00676 0.0 yhgF K Tex-like protein N-terminal domain protein
KGNHNLKD_00677 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KGNHNLKD_00678 2.9e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KGNHNLKD_00679 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
KGNHNLKD_00680 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KGNHNLKD_00681 2.7e-302 aspT P Predicted Permease Membrane Region
KGNHNLKD_00682 8.5e-249 EGP Major facilitator Superfamily
KGNHNLKD_00683 9.4e-110
KGNHNLKD_00686 1.3e-48 yjjH S Calcineurin-like phosphoesterase
KGNHNLKD_00687 4.2e-89 yjjH S Calcineurin-like phosphoesterase
KGNHNLKD_00688 1.3e-263 dtpT U amino acid peptide transporter
KGNHNLKD_00689 2.4e-18
KGNHNLKD_00691 4.2e-167 yqiG C Oxidoreductase
KGNHNLKD_00692 4.1e-62 S macrophage migration inhibitory factor
KGNHNLKD_00693 1.8e-65 K HxlR-like helix-turn-helix
KGNHNLKD_00694 1.2e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KGNHNLKD_00695 2.3e-58
KGNHNLKD_00696 1.1e-223 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KGNHNLKD_00697 3.7e-132 3.2.1.96, 3.5.1.28 GH73 M repeat protein
KGNHNLKD_00698 3.4e-51 M KxYKxGKxW signal domain protein
KGNHNLKD_00700 4.4e-44
KGNHNLKD_00701 6.3e-154 cylA V ABC transporter
KGNHNLKD_00702 1.3e-143 cylB V ABC-2 type transporter
KGNHNLKD_00703 7.6e-74 K LytTr DNA-binding domain
KGNHNLKD_00704 1.8e-60 S Protein of unknown function (DUF3021)
KGNHNLKD_00706 4.2e-175 L Plasmid pRiA4b ORF-3-like protein
KGNHNLKD_00707 2e-71 1.6.5.2 S NADPH-dependent FMN reductase
KGNHNLKD_00708 8.7e-85 K Bacterial regulatory proteins, tetR family
KGNHNLKD_00709 5.5e-86 entB 3.5.1.19 Q Isochorismatase family
KGNHNLKD_00710 7.9e-66 K Psort location Cytoplasmic, score
KGNHNLKD_00711 2.3e-35 K DNA binding
KGNHNLKD_00712 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
KGNHNLKD_00713 4.4e-243 mod 2.1.1.72, 3.1.21.5 L DNA methylase
KGNHNLKD_00714 2.6e-64
KGNHNLKD_00715 1.5e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KGNHNLKD_00716 4.6e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KGNHNLKD_00717 0.0 dnaK O Heat shock 70 kDa protein
KGNHNLKD_00718 6.8e-196 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KGNHNLKD_00719 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KGNHNLKD_00720 7.9e-249 pipD E Dipeptidase
KGNHNLKD_00721 1.1e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KGNHNLKD_00722 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KGNHNLKD_00723 2.2e-57
KGNHNLKD_00724 1.2e-180 prmA J Ribosomal protein L11 methyltransferase
KGNHNLKD_00725 1.3e-126 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KGNHNLKD_00726 1e-51
KGNHNLKD_00727 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KGNHNLKD_00728 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KGNHNLKD_00729 0.0 trxB2 1.8.1.9 C Thioredoxin domain
KGNHNLKD_00730 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
KGNHNLKD_00731 2.6e-139 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KGNHNLKD_00732 4.3e-118 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KGNHNLKD_00734 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KGNHNLKD_00735 2.7e-165 T Calcineurin-like phosphoesterase superfamily domain
KGNHNLKD_00736 3.1e-223 mdtG EGP Major facilitator Superfamily
KGNHNLKD_00737 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KGNHNLKD_00738 1.6e-221 yxjG_1 E methionine synthase, vitamin-B12 independent
KGNHNLKD_00739 4.3e-143 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
KGNHNLKD_00740 7.5e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KGNHNLKD_00741 7.4e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KGNHNLKD_00744 9.8e-112 yvyE 3.4.13.9 S YigZ family
KGNHNLKD_00745 4.1e-253 comFA L Helicase C-terminal domain protein
KGNHNLKD_00746 7.5e-126 comFC S Competence protein
KGNHNLKD_00747 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KGNHNLKD_00748 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KGNHNLKD_00749 3e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KGNHNLKD_00750 5.3e-32 KT PspC domain protein
KGNHNLKD_00751 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KGNHNLKD_00752 4.3e-175 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KGNHNLKD_00753 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KGNHNLKD_00754 5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KGNHNLKD_00755 4.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KGNHNLKD_00756 6.2e-134 yrjD S LUD domain
KGNHNLKD_00757 8.3e-287 lutB C 4Fe-4S dicluster domain
KGNHNLKD_00758 6.6e-167 lutA C Cysteine-rich domain
KGNHNLKD_00759 1.1e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KGNHNLKD_00760 8.2e-213 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KGNHNLKD_00761 2e-163 aatB ET PFAM extracellular solute-binding protein, family 3
KGNHNLKD_00762 3.9e-87 ykhA 3.1.2.20 I Thioesterase superfamily
KGNHNLKD_00763 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KGNHNLKD_00764 5.1e-116 yfbR S HD containing hydrolase-like enzyme
KGNHNLKD_00765 6.9e-14
KGNHNLKD_00766 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KGNHNLKD_00767 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KGNHNLKD_00768 2.1e-244 steT E amino acid
KGNHNLKD_00769 2.7e-160 rapZ S Displays ATPase and GTPase activities
KGNHNLKD_00770 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KGNHNLKD_00771 5.3e-170 whiA K May be required for sporulation
KGNHNLKD_00773 8.8e-15
KGNHNLKD_00774 9.7e-242 glpT G Major Facilitator Superfamily
KGNHNLKD_00775 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KGNHNLKD_00777 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KGNHNLKD_00778 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KGNHNLKD_00779 1.4e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KGNHNLKD_00780 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KGNHNLKD_00781 7.1e-248 yifK E Amino acid permease
KGNHNLKD_00782 6.9e-292 clcA P chloride
KGNHNLKD_00783 1.8e-34 secG U Preprotein translocase
KGNHNLKD_00784 3.4e-143 est 3.1.1.1 S Serine aminopeptidase, S33
KGNHNLKD_00785 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KGNHNLKD_00786 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KGNHNLKD_00787 4.1e-104 yxjI
KGNHNLKD_00788 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KGNHNLKD_00789 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KGNHNLKD_00790 6.5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KGNHNLKD_00791 3e-87 K Acetyltransferase (GNAT) domain
KGNHNLKD_00792 4.4e-76 S PAS domain
KGNHNLKD_00793 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
KGNHNLKD_00794 7.3e-169 murB 1.3.1.98 M Cell wall formation
KGNHNLKD_00795 3.8e-165 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KGNHNLKD_00797 1.3e-273 pipD E Dipeptidase
KGNHNLKD_00798 5.1e-311 yjbQ P TrkA C-terminal domain protein
KGNHNLKD_00799 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KGNHNLKD_00800 9.6e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KGNHNLKD_00801 1.9e-81
KGNHNLKD_00802 3.1e-34
KGNHNLKD_00803 1.4e-101 K DNA-templated transcription, initiation
KGNHNLKD_00804 2.2e-128
KGNHNLKD_00805 2.2e-69 K Transcriptional regulator, HxlR family
KGNHNLKD_00806 2.1e-169 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KGNHNLKD_00807 9e-140 epsB M biosynthesis protein
KGNHNLKD_00808 1.1e-119 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KGNHNLKD_00809 5.2e-52 pglC M Bacterial sugar transferase
KGNHNLKD_00810 1.3e-63 lsgF M Glycosyl transferase family 2
KGNHNLKD_00811 2.3e-65
KGNHNLKD_00812 3.3e-30 GT2 S Glycosyltransferase, group 2 family protein
KGNHNLKD_00813 1.2e-50 cps1B GT2,GT4 M Glycosyl transferases group 1
KGNHNLKD_00814 4.7e-28
KGNHNLKD_00815 2.6e-136 S polysaccharide biosynthetic process
KGNHNLKD_00816 6.3e-38
KGNHNLKD_00817 1.9e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KGNHNLKD_00818 1.3e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KGNHNLKD_00819 2.3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KGNHNLKD_00820 7.3e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KGNHNLKD_00821 3.3e-60 D nuclear chromosome segregation
KGNHNLKD_00822 1.6e-238 L Integrase core domain
KGNHNLKD_00823 4.9e-131 O Bacterial dnaA protein
KGNHNLKD_00825 6.8e-39
KGNHNLKD_00826 2.6e-258 S Putative peptidoglycan binding domain
KGNHNLKD_00829 1e-227 2.7.13.3 T GHKL domain
KGNHNLKD_00830 1.1e-138 K LytTr DNA-binding domain
KGNHNLKD_00832 1.2e-249 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KGNHNLKD_00834 8.5e-75 osmC O OsmC-like protein
KGNHNLKD_00835 3.6e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGNHNLKD_00836 4e-215 patA 2.6.1.1 E Aminotransferase
KGNHNLKD_00837 2.7e-32
KGNHNLKD_00838 0.0 clpL O associated with various cellular activities
KGNHNLKD_00839 7.8e-165 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KGNHNLKD_00841 8.8e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
KGNHNLKD_00842 5.9e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KGNHNLKD_00843 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KGNHNLKD_00844 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KGNHNLKD_00845 9.5e-172 malR K Transcriptional regulator, LacI family
KGNHNLKD_00846 2e-206 phbA 2.3.1.9 I Belongs to the thiolase family
KGNHNLKD_00847 1.1e-256 malT G Major Facilitator
KGNHNLKD_00848 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KGNHNLKD_00849 2.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KGNHNLKD_00850 5.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KGNHNLKD_00851 7.8e-137 puuD S peptidase C26
KGNHNLKD_00852 1.3e-167 yvgN C Aldo keto reductase
KGNHNLKD_00853 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
KGNHNLKD_00854 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
KGNHNLKD_00855 3.3e-86 hmpT S ECF-type riboflavin transporter, S component
KGNHNLKD_00856 3.8e-262 nox C NADH oxidase
KGNHNLKD_00857 3.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KGNHNLKD_00858 1.5e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KGNHNLKD_00859 1.4e-88
KGNHNLKD_00860 6e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KGNHNLKD_00862 2.1e-134 puuD S peptidase C26
KGNHNLKD_00863 6.7e-246 steT_1 E amino acid
KGNHNLKD_00864 1.6e-58 K Transcriptional regulator, TetR family
KGNHNLKD_00865 1.6e-39 K Transcriptional regulator, TetR family
KGNHNLKD_00866 1.4e-17
KGNHNLKD_00867 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KGNHNLKD_00868 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
KGNHNLKD_00869 1.3e-29 yjaB_1 K Acetyltransferase (GNAT) domain
KGNHNLKD_00870 5.9e-89 folT S ECF transporter, substrate-specific component
KGNHNLKD_00871 0.0 pepN 3.4.11.2 E aminopeptidase
KGNHNLKD_00872 5.5e-110 ylbE GM NAD dependent epimerase dehydratase family protein
KGNHNLKD_00873 6.3e-254 pepC 3.4.22.40 E aminopeptidase
KGNHNLKD_00874 1.4e-209 EGP Major facilitator Superfamily
KGNHNLKD_00875 2.5e-226
KGNHNLKD_00876 7.1e-80 K Transcriptional regulator, HxlR family
KGNHNLKD_00877 2e-48 XK27_02070 S Nitroreductase family
KGNHNLKD_00878 2.2e-35 XK27_02070 S Nitroreductase family
KGNHNLKD_00879 8.1e-51 hxlR K Transcriptional regulator, HxlR family
KGNHNLKD_00880 3e-10 GM NmrA-like family
KGNHNLKD_00881 3.6e-73 elaA S Gnat family
KGNHNLKD_00882 2.7e-38 S Cytochrome B5
KGNHNLKD_00883 5.4e-09 S Cytochrome B5
KGNHNLKD_00884 1.7e-40 S Cytochrome B5
KGNHNLKD_00885 8.8e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
KGNHNLKD_00886 4.2e-15 S Protein of unknown function (DUF3278)
KGNHNLKD_00887 2.5e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
KGNHNLKD_00889 4.4e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KGNHNLKD_00890 4.1e-240 E amino acid
KGNHNLKD_00891 9.9e-252 npp S type I phosphodiesterase nucleotide pyrophosphatase
KGNHNLKD_00892 8.1e-20 yxiO S Vacuole effluxer Atg22 like
KGNHNLKD_00893 2.3e-117 yxiO S Vacuole effluxer Atg22 like
KGNHNLKD_00894 1.2e-33 yxiO S Vacuole effluxer Atg22 like
KGNHNLKD_00896 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KGNHNLKD_00897 2.9e-29
KGNHNLKD_00898 8.6e-290 mntH P H( )-stimulated, divalent metal cation uptake system
KGNHNLKD_00899 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
KGNHNLKD_00900 6.3e-85 ygfC K transcriptional regulator (TetR family)
KGNHNLKD_00901 4.1e-171 hrtB V ABC transporter permease
KGNHNLKD_00902 3.9e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KGNHNLKD_00903 0.0 yhcA V ABC transporter, ATP-binding protein
KGNHNLKD_00904 1.3e-37
KGNHNLKD_00905 4.1e-50 czrA K Transcriptional regulator, ArsR family
KGNHNLKD_00906 3e-240 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KGNHNLKD_00907 2.8e-171 scrR K Transcriptional regulator, LacI family
KGNHNLKD_00908 1e-24
KGNHNLKD_00909 3.5e-106
KGNHNLKD_00910 6.2e-208 yttB EGP Major facilitator Superfamily
KGNHNLKD_00911 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KGNHNLKD_00912 8.5e-87
KGNHNLKD_00913 3e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
KGNHNLKD_00914 2.4e-259 S Putative peptidoglycan binding domain
KGNHNLKD_00915 1.2e-14
KGNHNLKD_00916 1.4e-121 yciB M ErfK YbiS YcfS YnhG
KGNHNLKD_00918 8.5e-102
KGNHNLKD_00919 1.5e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KGNHNLKD_00920 8e-125 S Alpha beta hydrolase
KGNHNLKD_00921 5.8e-208 gldA 1.1.1.6 C dehydrogenase
KGNHNLKD_00922 7.4e-132 ydiN G Major Facilitator Superfamily
KGNHNLKD_00923 5.1e-127 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KGNHNLKD_00924 6.5e-54 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KGNHNLKD_00925 1e-12 ydiN 5.4.99.5 G Major Facilitator
KGNHNLKD_00926 1.7e-162 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KGNHNLKD_00927 1.7e-35
KGNHNLKD_00928 2e-156 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KGNHNLKD_00929 7.8e-109 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KGNHNLKD_00930 6.5e-34 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KGNHNLKD_00931 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KGNHNLKD_00932 3.8e-41
KGNHNLKD_00933 2.1e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
KGNHNLKD_00934 8.9e-78 S C4-dicarboxylate anaerobic carrier
KGNHNLKD_00935 3e-190 S C4-dicarboxylate anaerobic carrier
KGNHNLKD_00936 4.1e-251 nhaC C Na H antiporter NhaC
KGNHNLKD_00937 2.1e-241 pbuX F xanthine permease
KGNHNLKD_00938 1.3e-281 pipD E Dipeptidase
KGNHNLKD_00939 9.7e-169 corA P CorA-like Mg2+ transporter protein
KGNHNLKD_00940 3.9e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KGNHNLKD_00941 6.6e-131 terC P membrane
KGNHNLKD_00942 3.6e-54 trxA O Belongs to the thioredoxin family
KGNHNLKD_00943 6.8e-56 K Transcriptional regulator, ArsR family
KGNHNLKD_00944 7.6e-84 P Cadmium resistance transporter
KGNHNLKD_00945 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
KGNHNLKD_00946 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KGNHNLKD_00947 1.3e-182 ABC-SBP S ABC transporter
KGNHNLKD_00948 2.3e-73 M PFAM NLP P60 protein
KGNHNLKD_00950 1.9e-99 S Protein of unknown function (DUF3278)
KGNHNLKD_00951 1.6e-32 WQ51_00220 K Helix-turn-helix domain
KGNHNLKD_00952 1.3e-48
KGNHNLKD_00953 3.3e-64 K Helix-turn-helix domain
KGNHNLKD_00954 9.3e-273 S ABC transporter, ATP-binding protein
KGNHNLKD_00955 2.3e-139 S Putative ABC-transporter type IV
KGNHNLKD_00956 2.9e-105 NU mannosyl-glycoprotein
KGNHNLKD_00957 2.2e-249 brnQ U Component of the transport system for branched-chain amino acids
KGNHNLKD_00958 1.4e-226 S Uncharacterized protein conserved in bacteria (DUF2325)
KGNHNLKD_00959 5.2e-198 nrnB S DHHA1 domain
KGNHNLKD_00960 3.1e-49
KGNHNLKD_00961 2.6e-125 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KGNHNLKD_00962 1.5e-18 S Domain of unknown function (DUF4767)
KGNHNLKD_00963 3.6e-54
KGNHNLKD_00964 1e-114 yrkL S Flavodoxin-like fold
KGNHNLKD_00966 5.4e-65 yeaO S Protein of unknown function, DUF488
KGNHNLKD_00967 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KGNHNLKD_00968 2.1e-205 3.1.3.1 S associated with various cellular activities
KGNHNLKD_00969 1.6e-233 S Putative metallopeptidase domain
KGNHNLKD_00970 4.6e-48
KGNHNLKD_00971 0.0 pepO 3.4.24.71 O Peptidase family M13
KGNHNLKD_00972 1.3e-108 K Helix-turn-helix domain
KGNHNLKD_00973 1.5e-86 ymdB S Macro domain protein
KGNHNLKD_00974 6.9e-196 EGP Major facilitator Superfamily
KGNHNLKD_00975 1.3e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KGNHNLKD_00976 6.7e-53 K helix_turn_helix, mercury resistance
KGNHNLKD_00977 7.7e-166 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KGNHNLKD_00978 3.6e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KGNHNLKD_00979 0.0 ysaB V FtsX-like permease family
KGNHNLKD_00980 1.4e-110 macB2 V ABC transporter, ATP-binding protein
KGNHNLKD_00981 2.8e-11 macB2 V ABC transporter, ATP-binding protein
KGNHNLKD_00982 1.4e-178 T PhoQ Sensor
KGNHNLKD_00983 4.1e-124 K response regulator
KGNHNLKD_00984 7.8e-157 ytbE 1.1.1.346 S Aldo keto reductase
KGNHNLKD_00985 1.2e-135 pnuC H nicotinamide mononucleotide transporter
KGNHNLKD_00986 2.9e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KGNHNLKD_00987 1.1e-203
KGNHNLKD_00988 2.6e-52
KGNHNLKD_00989 9.1e-36
KGNHNLKD_00990 2.6e-91 yxkA S Phosphatidylethanolamine-binding protein
KGNHNLKD_00991 9.2e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
KGNHNLKD_00992 1.4e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
KGNHNLKD_00993 4.5e-227 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KGNHNLKD_00994 5.3e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KGNHNLKD_00995 1.7e-179 galR K Transcriptional regulator
KGNHNLKD_00996 3.6e-95 dedA 3.1.3.1 S SNARE associated Golgi protein
KGNHNLKD_00997 4e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KGNHNLKD_00998 2.5e-80 K AsnC family
KGNHNLKD_00999 1.5e-80 uspA T universal stress protein
KGNHNLKD_01000 0.0 lacS G Transporter
KGNHNLKD_01001 3e-38
KGNHNLKD_01002 1.1e-267 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KGNHNLKD_01003 2.9e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KGNHNLKD_01004 3.4e-192 yeaN P Transporter, major facilitator family protein
KGNHNLKD_01005 4.6e-73 S 3-demethylubiquinone-9 3-methyltransferase
KGNHNLKD_01006 1.3e-84 nrdI F Belongs to the NrdI family
KGNHNLKD_01007 1.6e-241 yhdP S Transporter associated domain
KGNHNLKD_01008 1.4e-153 ypdB V (ABC) transporter
KGNHNLKD_01009 7.9e-91 GM epimerase
KGNHNLKD_01010 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
KGNHNLKD_01011 5.6e-77 yybA 2.3.1.57 K Transcriptional regulator
KGNHNLKD_01012 8.9e-133 XK27_07210 6.1.1.6 S B3 4 domain
KGNHNLKD_01013 2.7e-173 S AI-2E family transporter
KGNHNLKD_01014 4.6e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
KGNHNLKD_01015 7.9e-163
KGNHNLKD_01016 1.2e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KGNHNLKD_01017 7.8e-149 eutJ E Hsp70 protein
KGNHNLKD_01018 4.7e-199 K helix_turn_helix, arabinose operon control protein
KGNHNLKD_01019 6.2e-42 pduA_4 CQ BMC
KGNHNLKD_01020 2.7e-134 pduB E BMC
KGNHNLKD_01021 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
KGNHNLKD_01022 4.2e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
KGNHNLKD_01023 3.7e-77 pduE 4.2.1.28 Q Dehydratase small subunit
KGNHNLKD_01024 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
KGNHNLKD_01025 6.5e-60 pduH S Dehydratase medium subunit
KGNHNLKD_01026 1.4e-72 pduK CQ BMC
KGNHNLKD_01027 2.2e-42 pduA_4 CQ BMC
KGNHNLKD_01028 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
KGNHNLKD_01029 3.2e-89 S Putative propanediol utilisation
KGNHNLKD_01030 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
KGNHNLKD_01031 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
KGNHNLKD_01032 7.4e-80 pduO S Haem-degrading
KGNHNLKD_01033 8.9e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
KGNHNLKD_01034 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
KGNHNLKD_01035 1.4e-220 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KGNHNLKD_01036 5.5e-56 pduU E BMC
KGNHNLKD_01037 1.4e-147 3.1.3.48 T Pfam:Y_phosphatase3C
KGNHNLKD_01038 1.7e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
KGNHNLKD_01039 6.7e-80 P Cadmium resistance transporter
KGNHNLKD_01040 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
KGNHNLKD_01041 3.9e-78 fld C Flavodoxin
KGNHNLKD_01042 2.8e-154 XK27_04590 S NADPH-dependent FMN reductase
KGNHNLKD_01043 1.8e-101 cobO 2.5.1.17 S Cobalamin adenosyltransferase
KGNHNLKD_01044 2.1e-207 cobD 4.1.1.81 E Aminotransferase class I and II
KGNHNLKD_01045 1e-262 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
KGNHNLKD_01046 6.3e-179 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KGNHNLKD_01047 9.2e-124 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
KGNHNLKD_01048 3e-207 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KGNHNLKD_01049 9.7e-109 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KGNHNLKD_01050 1.7e-96 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
KGNHNLKD_01051 2.9e-134 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KGNHNLKD_01052 5.5e-192 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
KGNHNLKD_01053 1.8e-130 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KGNHNLKD_01054 6.4e-134 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
KGNHNLKD_01055 3.4e-258 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KGNHNLKD_01056 1.7e-145 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
KGNHNLKD_01057 1.3e-123 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
KGNHNLKD_01058 2.7e-132 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
KGNHNLKD_01059 1.9e-52 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
KGNHNLKD_01060 1.3e-117 cbiQ P Cobalt transport protein
KGNHNLKD_01061 1.1e-147 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
KGNHNLKD_01062 1.6e-274 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
KGNHNLKD_01063 6.7e-78 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
KGNHNLKD_01064 1.5e-228 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KGNHNLKD_01065 1.9e-164 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KGNHNLKD_01066 3.8e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
KGNHNLKD_01067 5.4e-250 hemL 5.4.3.8 H Aminotransferase class-III
KGNHNLKD_01068 2.3e-102 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
KGNHNLKD_01069 9.9e-135 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KGNHNLKD_01070 7e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
KGNHNLKD_01071 9e-130 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KGNHNLKD_01072 6.5e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
KGNHNLKD_01073 9.6e-62 S Domain of unknown function (DUF4430)
KGNHNLKD_01074 3.4e-81 S ECF transporter, substrate-specific component
KGNHNLKD_01075 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGNHNLKD_01076 6.5e-274 lmrA V ABC transporter, ATP-binding protein
KGNHNLKD_01077 0.0 yfiC V ABC transporter
KGNHNLKD_01078 1.4e-283 pipD E Dipeptidase
KGNHNLKD_01079 8.7e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KGNHNLKD_01080 5.2e-133 gntR K UbiC transcription regulator-associated domain protein
KGNHNLKD_01081 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KGNHNLKD_01082 1.5e-242 yagE E amino acid
KGNHNLKD_01083 9.4e-138 aroD S Serine hydrolase (FSH1)
KGNHNLKD_01084 2.2e-241 brnQ U Component of the transport system for branched-chain amino acids
KGNHNLKD_01085 3.4e-166 GK ROK family
KGNHNLKD_01086 0.0 tetP J elongation factor G
KGNHNLKD_01087 5.1e-81 uspA T universal stress protein
KGNHNLKD_01088 9.6e-194 lplA 6.3.1.20 H Lipoate-protein ligase
KGNHNLKD_01089 6e-62
KGNHNLKD_01090 5.2e-14
KGNHNLKD_01091 1.4e-106
KGNHNLKD_01092 1.5e-134 V ABC transporter
KGNHNLKD_01093 2.4e-212 EGP Major facilitator Superfamily
KGNHNLKD_01094 5.5e-256 G PTS system Galactitol-specific IIC component
KGNHNLKD_01095 5.6e-75 1.6.5.5 C Zinc-binding dehydrogenase
KGNHNLKD_01096 4e-16 1.6.5.5 C Zinc-binding dehydrogenase
KGNHNLKD_01097 3.5e-160
KGNHNLKD_01098 1e-72 K Transcriptional regulator
KGNHNLKD_01099 2.1e-190 D Alpha beta
KGNHNLKD_01100 2.2e-52 ypaA S Protein of unknown function (DUF1304)
KGNHNLKD_01101 0.0 yjcE P Sodium proton antiporter
KGNHNLKD_01102 1.6e-52 yvlA
KGNHNLKD_01103 3.5e-112 P Cobalt transport protein
KGNHNLKD_01104 7.8e-239 cbiO1 S ABC transporter, ATP-binding protein
KGNHNLKD_01105 1.6e-94 S ABC-type cobalt transport system, permease component
KGNHNLKD_01106 2.7e-21 yjeM E Amino Acid
KGNHNLKD_01107 6.7e-192 yjeM E Amino Acid
KGNHNLKD_01108 1.3e-129 S membrane transporter protein
KGNHNLKD_01109 3e-213 bacI V MacB-like periplasmic core domain
KGNHNLKD_01110 9.8e-129 V ABC transporter
KGNHNLKD_01111 6.3e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KGNHNLKD_01112 5.2e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KGNHNLKD_01113 6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KGNHNLKD_01114 3e-147 E Glyoxalase-like domain
KGNHNLKD_01115 3.2e-225 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
KGNHNLKD_01116 2.2e-96 S reductase
KGNHNLKD_01117 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KGNHNLKD_01118 3e-176 ABC-SBP S ABC transporter
KGNHNLKD_01119 4.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
KGNHNLKD_01120 1.9e-218 htrA 3.4.21.107 O serine protease
KGNHNLKD_01121 8.6e-153 vicX 3.1.26.11 S domain protein
KGNHNLKD_01122 5.4e-150 yycI S YycH protein
KGNHNLKD_01123 1.5e-247 yycH S YycH protein
KGNHNLKD_01124 0.0 vicK 2.7.13.3 T Histidine kinase
KGNHNLKD_01125 5.2e-130 K response regulator
KGNHNLKD_01127 7.6e-308 lmrA 3.6.3.44 V ABC transporter
KGNHNLKD_01128 2.3e-72 K helix_turn_helix multiple antibiotic resistance protein
KGNHNLKD_01130 1.3e-123 Z012_01130 S Fic/DOC family
KGNHNLKD_01131 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
KGNHNLKD_01132 8.2e-54
KGNHNLKD_01133 5.8e-206 yttB EGP Major facilitator Superfamily
KGNHNLKD_01134 9e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KGNHNLKD_01135 7.6e-74 rplI J Binds to the 23S rRNA
KGNHNLKD_01136 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KGNHNLKD_01137 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KGNHNLKD_01138 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KGNHNLKD_01139 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KGNHNLKD_01140 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KGNHNLKD_01141 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KGNHNLKD_01142 6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KGNHNLKD_01143 1.7e-34 yaaA S S4 domain protein YaaA
KGNHNLKD_01144 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KGNHNLKD_01145 5.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KGNHNLKD_01146 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KGNHNLKD_01147 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KGNHNLKD_01148 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KGNHNLKD_01149 3.9e-131 jag S R3H domain protein
KGNHNLKD_01150 8.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KGNHNLKD_01151 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KGNHNLKD_01152 0.0 asnB 6.3.5.4 E Asparagine synthase
KGNHNLKD_01153 6.9e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KGNHNLKD_01154 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
KGNHNLKD_01155 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KGNHNLKD_01156 8.1e-88 2.3.1.183 M Acetyltransferase GNAT family
KGNHNLKD_01157 3.5e-160 S reductase
KGNHNLKD_01159 1.9e-07 yiiE S Protein of unknown function (DUF1211)
KGNHNLKD_01161 7.5e-57 K LysR substrate binding domain
KGNHNLKD_01162 6.2e-102 S amidohydrolase
KGNHNLKD_01163 1e-176 S amidohydrolase
KGNHNLKD_01164 3e-116 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KGNHNLKD_01166 1.3e-69 S GyrI-like small molecule binding domain
KGNHNLKD_01167 8e-120 yhiD S MgtC family
KGNHNLKD_01168 6.2e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KGNHNLKD_01169 9.2e-192 V Beta-lactamase
KGNHNLKD_01170 4.5e-73 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KGNHNLKD_01171 2.3e-72 XK27_08850 J Aminoacyl-tRNA editing domain
KGNHNLKD_01172 0.0 M LPXTG-motif cell wall anchor domain protein
KGNHNLKD_01173 1.2e-188 nss M transferase activity, transferring glycosyl groups
KGNHNLKD_01174 1.1e-49 cpsJ S glycosyl transferase family 2
KGNHNLKD_01175 1.5e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
KGNHNLKD_01176 1e-287 M transferase activity, transferring glycosyl groups
KGNHNLKD_01177 6.4e-287 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
KGNHNLKD_01178 1.8e-164 asp3 S Accessory Sec secretory system ASP3
KGNHNLKD_01179 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KGNHNLKD_01180 9.8e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KGNHNLKD_01181 3.7e-254 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KGNHNLKD_01183 2e-12 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KGNHNLKD_01184 2.2e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KGNHNLKD_01185 2.6e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KGNHNLKD_01186 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KGNHNLKD_01187 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KGNHNLKD_01188 4.5e-49 ylxQ J ribosomal protein
KGNHNLKD_01189 2.3e-44 ylxR K Protein of unknown function (DUF448)
KGNHNLKD_01190 1.2e-214 nusA K Participates in both transcription termination and antitermination
KGNHNLKD_01191 1.9e-83 rimP J Required for maturation of 30S ribosomal subunits
KGNHNLKD_01192 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KGNHNLKD_01193 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KGNHNLKD_01194 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KGNHNLKD_01195 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
KGNHNLKD_01196 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KGNHNLKD_01197 3.7e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KGNHNLKD_01198 1.3e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KGNHNLKD_01199 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KGNHNLKD_01200 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
KGNHNLKD_01201 9.8e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGNHNLKD_01202 3.9e-47 yazA L GIY-YIG catalytic domain protein
KGNHNLKD_01203 7.8e-140 yabB 2.1.1.223 L Methyltransferase small domain
KGNHNLKD_01204 7.8e-117 plsC 2.3.1.51 I Acyltransferase
KGNHNLKD_01205 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
KGNHNLKD_01206 6.6e-35 ynzC S UPF0291 protein
KGNHNLKD_01207 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KGNHNLKD_01208 6.8e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KGNHNLKD_01209 5.7e-126 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KGNHNLKD_01215 1.8e-14
KGNHNLKD_01216 5.3e-57 S D5 N terminal like
KGNHNLKD_01219 9.3e-08
KGNHNLKD_01221 1.5e-40 S Phage regulatory protein Rha (Phage_pRha)
KGNHNLKD_01223 6e-13 K Transcriptional
KGNHNLKD_01224 1.1e-34 S Domain of unknown function (DUF5067)
KGNHNLKD_01225 3e-132 L Belongs to the 'phage' integrase family
KGNHNLKD_01227 8.4e-16
KGNHNLKD_01229 1.4e-18
KGNHNLKD_01231 7.8e-51 S CRISPR-associated protein (Cas_Csn2)
KGNHNLKD_01232 6.5e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KGNHNLKD_01233 7e-111 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KGNHNLKD_01234 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KGNHNLKD_01235 9.5e-83
KGNHNLKD_01236 5.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
KGNHNLKD_01237 2.1e-52 S Mazg nucleotide pyrophosphohydrolase
KGNHNLKD_01238 3.4e-35
KGNHNLKD_01239 3.4e-152 yeaE S Aldo keto
KGNHNLKD_01240 1.2e-76 hsp O Belongs to the small heat shock protein (HSP20) family
KGNHNLKD_01241 4e-281 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
KGNHNLKD_01242 4.5e-79 S Psort location Cytoplasmic, score
KGNHNLKD_01243 2.9e-85 S Short repeat of unknown function (DUF308)
KGNHNLKD_01244 1e-23
KGNHNLKD_01245 2.8e-102 V VanZ like family
KGNHNLKD_01246 7.4e-226 cycA E Amino acid permease
KGNHNLKD_01247 4.3e-85 perR P Belongs to the Fur family
KGNHNLKD_01248 7.1e-259 EGP Major facilitator Superfamily
KGNHNLKD_01249 1.1e-95 tag 3.2.2.20 L glycosylase
KGNHNLKD_01250 3.6e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KGNHNLKD_01251 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KGNHNLKD_01252 6.4e-41
KGNHNLKD_01253 3.8e-256 ytgP S Polysaccharide biosynthesis protein
KGNHNLKD_01254 2.1e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KGNHNLKD_01255 3.1e-275 pepV 3.5.1.18 E dipeptidase PepV
KGNHNLKD_01256 1.2e-85 uspA T Belongs to the universal stress protein A family
KGNHNLKD_01257 8.3e-177 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KGNHNLKD_01258 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
KGNHNLKD_01259 2.2e-113
KGNHNLKD_01260 2.5e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
KGNHNLKD_01261 1.7e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KGNHNLKD_01262 7.1e-74 mrr L restriction endonuclease
KGNHNLKD_01263 0.0 L PLD-like domain
KGNHNLKD_01265 1.7e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KGNHNLKD_01266 1.4e-195 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KGNHNLKD_01267 7.4e-101 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KGNHNLKD_01268 9.4e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KGNHNLKD_01269 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KGNHNLKD_01270 1.9e-103 T Ion transport 2 domain protein
KGNHNLKD_01271 0.0 S Bacterial membrane protein YfhO
KGNHNLKD_01272 2.6e-206 G Transporter, major facilitator family protein
KGNHNLKD_01273 7.1e-109 yvrI K RNA polymerase sigma factor, sigma-70 family
KGNHNLKD_01274 1.2e-64 ydiI Q Thioesterase superfamily
KGNHNLKD_01275 1.9e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KGNHNLKD_01276 2.4e-267 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KGNHNLKD_01277 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KGNHNLKD_01278 4.2e-32 feoA P FeoA domain
KGNHNLKD_01279 6.5e-145 sufC O FeS assembly ATPase SufC
KGNHNLKD_01280 6.2e-238 sufD O FeS assembly protein SufD
KGNHNLKD_01281 2.8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KGNHNLKD_01282 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
KGNHNLKD_01283 3e-270 sufB O assembly protein SufB
KGNHNLKD_01284 4.7e-57 yitW S Iron-sulfur cluster assembly protein
KGNHNLKD_01285 1.5e-158 hipB K Helix-turn-helix
KGNHNLKD_01286 4.8e-100 nreC K PFAM regulatory protein LuxR
KGNHNLKD_01287 9.2e-39 S Cytochrome B5
KGNHNLKD_01288 1.7e-153 yitU 3.1.3.104 S hydrolase
KGNHNLKD_01289 3.8e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KGNHNLKD_01290 2.6e-147 f42a O Band 7 protein
KGNHNLKD_01291 4.6e-53 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
KGNHNLKD_01292 1.4e-256 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
KGNHNLKD_01293 1.2e-129 lytT K response regulator receiver
KGNHNLKD_01294 1.9e-66 lrgA S LrgA family
KGNHNLKD_01295 2.2e-123 lrgB M LrgB-like family
KGNHNLKD_01296 9.3e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KGNHNLKD_01297 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KGNHNLKD_01298 3.7e-185 galR K Periplasmic binding protein-like domain
KGNHNLKD_01299 0.0 rafA 3.2.1.22 G alpha-galactosidase
KGNHNLKD_01305 1.6e-133 L Transposase
KGNHNLKD_01306 2e-208 L Belongs to the 'phage' integrase family
KGNHNLKD_01307 4.1e-50
KGNHNLKD_01308 3.3e-111 S SIR2-like domain
KGNHNLKD_01310 4.8e-44
KGNHNLKD_01311 6.2e-11
KGNHNLKD_01312 1.4e-80 E IrrE N-terminal-like domain
KGNHNLKD_01313 1.3e-70 K Cro/C1-type HTH DNA-binding domain
KGNHNLKD_01314 9.7e-29 K Helix-turn-helix XRE-family like proteins
KGNHNLKD_01316 1.4e-15 S Hypothetical protein (DUF2513)
KGNHNLKD_01317 1.6e-18
KGNHNLKD_01319 1e-30
KGNHNLKD_01322 9.6e-51 S Bacteriophage Mu Gam like protein
KGNHNLKD_01323 3e-122 S AAA domain
KGNHNLKD_01324 9.4e-93 S Protein of unknown function (DUF669)
KGNHNLKD_01325 9e-66 S Putative HNHc nuclease
KGNHNLKD_01326 1.1e-12 V endonuclease activity
KGNHNLKD_01327 1.4e-72 L Psort location Cytoplasmic, score
KGNHNLKD_01328 1.8e-24
KGNHNLKD_01331 7.3e-52 S ORF6C domain
KGNHNLKD_01334 3e-15
KGNHNLKD_01337 3.8e-13
KGNHNLKD_01340 1.7e-37
KGNHNLKD_01347 1.2e-109 xtmA L Terminase small subunit
KGNHNLKD_01348 5.6e-215 S Terminase-like family
KGNHNLKD_01349 2.3e-212 S Phage portal protein, SPP1 Gp6-like
KGNHNLKD_01350 8.1e-151 S Phage Mu protein F like protein
KGNHNLKD_01351 7.6e-51 S Domain of unknown function (DUF4355)
KGNHNLKD_01352 3.2e-54
KGNHNLKD_01353 4.7e-167 S Phage major capsid protein E
KGNHNLKD_01354 2.1e-35
KGNHNLKD_01355 3.2e-59
KGNHNLKD_01356 6.6e-80
KGNHNLKD_01357 3.6e-50
KGNHNLKD_01358 1.3e-71 S Phage tail tube protein, TTP
KGNHNLKD_01359 4.5e-57
KGNHNLKD_01360 2.3e-33
KGNHNLKD_01361 0.0 M Phage tail tape measure protein TP901
KGNHNLKD_01362 1.1e-51
KGNHNLKD_01363 1.4e-85 GT2,GT4 LM gp58-like protein
KGNHNLKD_01364 9.9e-236 GT2,GT4 LM gp58-like protein
KGNHNLKD_01366 7.3e-13
KGNHNLKD_01367 7.7e-16 S Bacteriophage holin family
KGNHNLKD_01368 5.9e-185 M lysozyme activity
KGNHNLKD_01369 8.5e-96
KGNHNLKD_01370 2.1e-25
KGNHNLKD_01371 1.3e-61 asp S Asp23 family, cell envelope-related function
KGNHNLKD_01372 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
KGNHNLKD_01374 6e-49
KGNHNLKD_01375 1.8e-68 yqkB S Belongs to the HesB IscA family
KGNHNLKD_01376 2.5e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
KGNHNLKD_01377 1.2e-82 F NUDIX domain
KGNHNLKD_01378 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KGNHNLKD_01379 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KGNHNLKD_01380 9.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KGNHNLKD_01381 2.3e-167 lacX 5.1.3.3 G Aldose 1-epimerase
KGNHNLKD_01382 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KGNHNLKD_01383 2.7e-160 dprA LU DNA protecting protein DprA
KGNHNLKD_01384 7.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KGNHNLKD_01385 3.5e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KGNHNLKD_01386 6.4e-34 yozE S Belongs to the UPF0346 family
KGNHNLKD_01387 3.6e-88 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
KGNHNLKD_01388 1.9e-172 ypmR E lipolytic protein G-D-S-L family
KGNHNLKD_01389 4.4e-152 DegV S EDD domain protein, DegV family
KGNHNLKD_01390 5.3e-113 hlyIII S protein, hemolysin III
KGNHNLKD_01391 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KGNHNLKD_01392 1.2e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KGNHNLKD_01393 0.0 yfmR S ABC transporter, ATP-binding protein
KGNHNLKD_01394 5.3e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KGNHNLKD_01395 9.7e-236 S Tetratricopeptide repeat protein
KGNHNLKD_01396 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KGNHNLKD_01397 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KGNHNLKD_01398 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
KGNHNLKD_01399 3e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KGNHNLKD_01400 8.5e-14 M Lysin motif
KGNHNLKD_01401 1.5e-264 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
KGNHNLKD_01402 1.2e-186 ypbB 5.1.3.1 S Helix-turn-helix domain
KGNHNLKD_01403 5.8e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KGNHNLKD_01404 1.2e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KGNHNLKD_01405 8.5e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KGNHNLKD_01406 4.8e-140 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KGNHNLKD_01407 1.6e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KGNHNLKD_01408 7.7e-163 xerD D recombinase XerD
KGNHNLKD_01409 1.9e-166 cvfB S S1 domain
KGNHNLKD_01410 8e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KGNHNLKD_01411 0.0 dnaE 2.7.7.7 L DNA polymerase
KGNHNLKD_01412 2.3e-30 S Protein of unknown function (DUF2929)
KGNHNLKD_01413 8.1e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KGNHNLKD_01414 2e-157 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KGNHNLKD_01415 1.1e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
KGNHNLKD_01416 1.4e-220 patA 2.6.1.1 E Aminotransferase
KGNHNLKD_01417 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KGNHNLKD_01418 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KGNHNLKD_01419 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KGNHNLKD_01420 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KGNHNLKD_01421 4e-147 recO L Involved in DNA repair and RecF pathway recombination
KGNHNLKD_01422 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KGNHNLKD_01423 1.9e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KGNHNLKD_01424 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KGNHNLKD_01425 1.1e-181 phoH T phosphate starvation-inducible protein PhoH
KGNHNLKD_01426 3.3e-167 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KGNHNLKD_01427 7.1e-79 bioY S BioY family
KGNHNLKD_01428 6.4e-265 argH 4.3.2.1 E argininosuccinate lyase
KGNHNLKD_01429 1.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KGNHNLKD_01430 9.3e-186 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KGNHNLKD_01431 1.9e-69 yqeY S YqeY-like protein
KGNHNLKD_01432 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KGNHNLKD_01433 3.1e-74 glnPH2 P ABC transporter permease
KGNHNLKD_01434 3.1e-176 glnPH2 P ABC transporter permease
KGNHNLKD_01435 2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KGNHNLKD_01436 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KGNHNLKD_01437 6e-165 yniA G Phosphotransferase enzyme family
KGNHNLKD_01438 2.8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
KGNHNLKD_01439 1.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KGNHNLKD_01440 9.1e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
KGNHNLKD_01441 3e-249 yagE E amino acid
KGNHNLKD_01442 2.9e-84 dps P Belongs to the Dps family
KGNHNLKD_01443 0.0 pacL 3.6.3.8 P P-type ATPase
KGNHNLKD_01444 1.9e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KGNHNLKD_01445 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KGNHNLKD_01446 2.2e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KGNHNLKD_01447 2.5e-144 potB P ABC transporter permease
KGNHNLKD_01448 2.7e-138 potC P ABC transporter permease
KGNHNLKD_01449 1.6e-207 potD P ABC transporter
KGNHNLKD_01450 4.3e-231
KGNHNLKD_01451 9.4e-234 EGP Sugar (and other) transporter
KGNHNLKD_01452 2.7e-255 yfnA E Amino Acid
KGNHNLKD_01453 3.4e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KGNHNLKD_01454 1.4e-101 gmk2 2.7.4.8 F Guanylate kinase
KGNHNLKD_01455 1.5e-82 zur P Belongs to the Fur family
KGNHNLKD_01456 3.1e-17 3.2.1.14 GH18
KGNHNLKD_01457 5.4e-150
KGNHNLKD_01458 8.3e-38 pspC KT PspC domain protein
KGNHNLKD_01459 1.6e-94 K Transcriptional regulator (TetR family)
KGNHNLKD_01460 2.9e-235 V domain protein
KGNHNLKD_01461 8.7e-179 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KGNHNLKD_01463 6.6e-35 S Transglycosylase associated protein
KGNHNLKD_01464 1.6e-233 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KGNHNLKD_01465 1.9e-126 G phosphoglycerate mutase
KGNHNLKD_01466 5.7e-115 dedA S SNARE associated Golgi protein
KGNHNLKD_01467 0.0 helD 3.6.4.12 L DNA helicase
KGNHNLKD_01468 3e-243 nox C NADH oxidase
KGNHNLKD_01469 2.9e-254 nox C NADH oxidase
KGNHNLKD_01470 2.5e-158 EG EamA-like transporter family
KGNHNLKD_01471 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KGNHNLKD_01472 1.3e-176 coaA 2.7.1.33 F Pantothenic acid kinase
KGNHNLKD_01473 1.1e-223 S cog cog1373
KGNHNLKD_01475 2e-299 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KGNHNLKD_01476 5.6e-158 spoU 2.1.1.185 J Methyltransferase
KGNHNLKD_01477 9.9e-128 S PFAM Archaeal ATPase
KGNHNLKD_01478 5.9e-99 crp_2 K Cyclic nucleotide-binding domain
KGNHNLKD_01479 1.6e-126 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
KGNHNLKD_01480 1.2e-137 pnuC H nicotinamide mononucleotide transporter
KGNHNLKD_01481 2.5e-225 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KGNHNLKD_01482 1.6e-100 ywlG S Belongs to the UPF0340 family
KGNHNLKD_01483 1.8e-53 S ParE toxin of type II toxin-antitoxin system, parDE
KGNHNLKD_01484 2e-36 D Antitoxin component of a toxin-antitoxin (TA) module
KGNHNLKD_01485 4e-196 EGP Major facilitator Superfamily
KGNHNLKD_01486 7.4e-120 M Lysin motif
KGNHNLKD_01487 1.6e-79
KGNHNLKD_01488 4.4e-169 P CorA-like Mg2+ transporter protein
KGNHNLKD_01489 5.6e-97 wecD3 K PFAM GCN5-related N-acetyltransferase
KGNHNLKD_01490 1.1e-204 cytX U Belongs to the purine-cytosine permease (2.A.39) family
KGNHNLKD_01491 4.3e-13
KGNHNLKD_01492 3.8e-78 S Domain of unknown function (DUF4767)
KGNHNLKD_01493 4.1e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KGNHNLKD_01494 1.3e-113 S Membrane
KGNHNLKD_01495 8.4e-125 O Zinc-dependent metalloprotease
KGNHNLKD_01496 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KGNHNLKD_01497 2.3e-159 metQ_4 P Belongs to the nlpA lipoprotein family
KGNHNLKD_01499 0.0 UW LPXTG-motif cell wall anchor domain protein
KGNHNLKD_01500 6.3e-45 UW LPXTG-motif cell wall anchor domain protein
KGNHNLKD_01501 0.0 UW LPXTG-motif cell wall anchor domain protein
KGNHNLKD_01502 0.0 UW LPXTG-motif cell wall anchor domain protein
KGNHNLKD_01503 0.0 UW LPXTG-motif cell wall anchor domain protein
KGNHNLKD_01504 4.9e-183 S Phosphotransferase system, EIIC
KGNHNLKD_01505 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KGNHNLKD_01506 5.8e-170
KGNHNLKD_01508 3.5e-15 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KGNHNLKD_01509 6.6e-23 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KGNHNLKD_01510 2.8e-96 2.3.1.128 K acetyltransferase
KGNHNLKD_01511 6.4e-22
KGNHNLKD_01512 1.7e-32
KGNHNLKD_01513 4.8e-36
KGNHNLKD_01514 1e-13 K Transcriptional regulator, HxlR family
KGNHNLKD_01515 2.1e-216 P ammonium transporter
KGNHNLKD_01516 2.1e-96 ureI S AmiS/UreI family transporter
KGNHNLKD_01517 3.7e-48 ureA 3.5.1.5 E Urease, gamma subunit
KGNHNLKD_01518 2.1e-69 ureB 3.5.1.5 E Urease beta subunit
KGNHNLKD_01519 0.0 ureC 3.5.1.5 E Amidohydrolase family
KGNHNLKD_01520 1.9e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KGNHNLKD_01521 1.9e-132 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KGNHNLKD_01522 1.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KGNHNLKD_01523 2.4e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KGNHNLKD_01524 4e-34 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KGNHNLKD_01525 1e-182 nikMN P PDGLE domain
KGNHNLKD_01526 2.1e-133 P Cobalt transport protein
KGNHNLKD_01527 8.6e-136 cbiO P ABC transporter
KGNHNLKD_01528 5.2e-105 fhaB M Rib/alpha-like repeat
KGNHNLKD_01529 0.0 infB UW LPXTG-motif cell wall anchor domain protein
KGNHNLKD_01530 3.2e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KGNHNLKD_01531 1.8e-265 glnP P ABC transporter
KGNHNLKD_01532 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KGNHNLKD_01534 2.7e-220 cycA E Amino acid permease
KGNHNLKD_01535 1e-218 nupG F Nucleoside transporter
KGNHNLKD_01536 3.3e-169 rihC 3.2.2.1 F Nucleoside
KGNHNLKD_01537 4.2e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
KGNHNLKD_01538 6.6e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KGNHNLKD_01539 9.6e-151 noc K Belongs to the ParB family
KGNHNLKD_01540 3.9e-139 soj D Sporulation initiation inhibitor
KGNHNLKD_01541 6.5e-154 spo0J K Belongs to the ParB family
KGNHNLKD_01542 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
KGNHNLKD_01543 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KGNHNLKD_01544 5.9e-135 XK27_01040 S Protein of unknown function (DUF1129)
KGNHNLKD_01545 9.8e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KGNHNLKD_01546 3.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KGNHNLKD_01547 1.7e-235 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
KGNHNLKD_01548 3.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KGNHNLKD_01549 5.6e-172 deoR K sugar-binding domain protein
KGNHNLKD_01550 1.2e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KGNHNLKD_01551 3.8e-125 K response regulator
KGNHNLKD_01552 4.1e-201 hpk31 2.7.13.3 T Histidine kinase
KGNHNLKD_01553 3.2e-140 azlC E AzlC protein
KGNHNLKD_01554 5.6e-53 azlD S branched-chain amino acid
KGNHNLKD_01555 3.3e-134 K LysR substrate binding domain
KGNHNLKD_01556 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KGNHNLKD_01557 6.9e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KGNHNLKD_01558 1.9e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KGNHNLKD_01559 2.7e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KGNHNLKD_01560 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KGNHNLKD_01561 3.7e-106 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
KGNHNLKD_01562 1.4e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KGNHNLKD_01563 1.1e-176 K AI-2E family transporter
KGNHNLKD_01564 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KGNHNLKD_01565 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KGNHNLKD_01566 3.6e-126 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KGNHNLKD_01567 7.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KGNHNLKD_01568 7.1e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KGNHNLKD_01569 6.9e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KGNHNLKD_01570 4.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KGNHNLKD_01571 1.3e-35 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KGNHNLKD_01572 1.7e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KGNHNLKD_01573 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KGNHNLKD_01574 1.1e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KGNHNLKD_01575 1.7e-190 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KGNHNLKD_01576 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KGNHNLKD_01577 8e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KGNHNLKD_01578 2.6e-241 purD 6.3.4.13 F Belongs to the GARS family
KGNHNLKD_01579 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KGNHNLKD_01580 3.1e-163
KGNHNLKD_01581 4.9e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KGNHNLKD_01582 1.3e-39 amtB P ammonium transporter
KGNHNLKD_01583 4.6e-244 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
KGNHNLKD_01584 1e-88
KGNHNLKD_01585 3.3e-118 pnb C nitroreductase
KGNHNLKD_01586 1.2e-29 XK27_00915 C Luciferase-like monooxygenase
KGNHNLKD_01587 3.8e-32 XK27_00915 C Luciferase-like monooxygenase
KGNHNLKD_01588 3.1e-138 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KGNHNLKD_01589 1.2e-68 S Protein of unknown function (DUF3021)
KGNHNLKD_01590 5.2e-72 K LytTr DNA-binding domain
KGNHNLKD_01591 5.5e-21
KGNHNLKD_01592 7.8e-118 ybhL S Belongs to the BI1 family
KGNHNLKD_01593 1.3e-70 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
KGNHNLKD_01594 7.6e-191 S Protein of unknown function (DUF3114)
KGNHNLKD_01595 6.8e-292 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KGNHNLKD_01596 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KGNHNLKD_01597 2e-103 yvdD 3.2.2.10 S Belongs to the LOG family
KGNHNLKD_01598 3.9e-228 3.1.21.3 L N-6 DNA Methylase
KGNHNLKD_01599 8.1e-280 L Transposase
KGNHNLKD_01600 6.7e-32
KGNHNLKD_01602 5.2e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KGNHNLKD_01603 5.9e-250 mmuP E amino acid
KGNHNLKD_01607 0.0 snf 2.7.11.1 KL domain protein
KGNHNLKD_01608 3.4e-143 ywqE 3.1.3.48 GM PHP domain protein
KGNHNLKD_01609 1.2e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KGNHNLKD_01610 0.0 sbcC L Putative exonuclease SbcCD, C subunit
KGNHNLKD_01611 2.4e-95 L nuclease
KGNHNLKD_01612 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
KGNHNLKD_01613 3.3e-71
KGNHNLKD_01614 6.3e-102 fic D Fic/DOC family
KGNHNLKD_01615 1.2e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KGNHNLKD_01616 1.9e-150 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KGNHNLKD_01617 6.6e-19
KGNHNLKD_01618 5.8e-42
KGNHNLKD_01619 1.5e-95
KGNHNLKD_01620 4.6e-24
KGNHNLKD_01621 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KGNHNLKD_01622 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KGNHNLKD_01623 2.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KGNHNLKD_01625 3.3e-40
KGNHNLKD_01626 1.4e-43
KGNHNLKD_01627 2.1e-216 folP 2.5.1.15 H dihydropteroate synthase
KGNHNLKD_01628 1.4e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
KGNHNLKD_01629 1.7e-224 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KGNHNLKD_01630 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
KGNHNLKD_01631 9.1e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KGNHNLKD_01632 5.3e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KGNHNLKD_01633 3.8e-69
KGNHNLKD_01635 1.9e-43
KGNHNLKD_01636 1.3e-117 S CAAX protease self-immunity
KGNHNLKD_01637 2.1e-32
KGNHNLKD_01638 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
KGNHNLKD_01639 1.3e-177 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KGNHNLKD_01640 7.7e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
KGNHNLKD_01641 1.8e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KGNHNLKD_01642 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KGNHNLKD_01643 2.7e-39 ptsH G phosphocarrier protein HPR
KGNHNLKD_01644 6.4e-27
KGNHNLKD_01645 0.0 clpE O Belongs to the ClpA ClpB family
KGNHNLKD_01646 1.7e-100 S Pfam:DUF3816
KGNHNLKD_01647 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
KGNHNLKD_01648 4.8e-112
KGNHNLKD_01649 9.8e-155 V ABC transporter, ATP-binding protein
KGNHNLKD_01650 2.7e-64 gntR1 K Transcriptional regulator, GntR family
KGNHNLKD_01651 3.2e-178 3.2.1.23, 3.2.1.89 G arabinogalactan endo-1,4-beta-galactosidase activity
KGNHNLKD_01652 1.5e-197 ganB 3.2.1.89 G arabinogalactan
KGNHNLKD_01653 1.7e-35 S dextransucrase activity
KGNHNLKD_01654 7.2e-91 L PFAM Integrase catalytic region
KGNHNLKD_01655 2.1e-162 L hmm pf00665
KGNHNLKD_01656 2.8e-114 L Helix-turn-helix domain
KGNHNLKD_01657 2.7e-302 L Transposase
KGNHNLKD_01658 7.2e-56 L PFAM Integrase catalytic region
KGNHNLKD_01659 7.7e-43 L Helix-turn-helix domain
KGNHNLKD_01660 9.6e-158 pstS P Phosphate
KGNHNLKD_01661 4.7e-152 pstC P probably responsible for the translocation of the substrate across the membrane
KGNHNLKD_01662 1.4e-153 pstA P Phosphate transport system permease protein PstA
KGNHNLKD_01663 3.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KGNHNLKD_01664 2.1e-123 phoU P Plays a role in the regulation of phosphate uptake
KGNHNLKD_01665 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
KGNHNLKD_01666 1.1e-181 L Helix-turn-helix domain
KGNHNLKD_01667 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
KGNHNLKD_01668 4.1e-62 yneR
KGNHNLKD_01669 5.6e-158 akr5f 1.1.1.346 S reductase
KGNHNLKD_01670 1.6e-152 K Transcriptional regulator
KGNHNLKD_01671 2e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
KGNHNLKD_01672 4.2e-165 ypuA S Protein of unknown function (DUF1002)
KGNHNLKD_01673 1.9e-57 padR K Virulence activator alpha C-term
KGNHNLKD_01674 7.5e-92 padC Q Phenolic acid decarboxylase
KGNHNLKD_01675 6.5e-38 C Flavodoxin
KGNHNLKD_01676 1.6e-114 S Oxidoreductase, aldo keto reductase family protein
KGNHNLKD_01677 4.2e-53 yphJ 4.1.1.44 S decarboxylase
KGNHNLKD_01678 2.4e-10 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
KGNHNLKD_01679 2.5e-114 P nitric oxide dioxygenase activity
KGNHNLKD_01680 1.8e-108 S Peptidase propeptide and YPEB domain
KGNHNLKD_01681 1.5e-239 T GHKL domain
KGNHNLKD_01682 3e-40 T Transcriptional regulatory protein, C terminal
KGNHNLKD_01683 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KGNHNLKD_01684 4.9e-99 yceD S Uncharacterized ACR, COG1399
KGNHNLKD_01685 3e-212 ylbM S Belongs to the UPF0348 family
KGNHNLKD_01686 2.1e-137 yqeM Q Methyltransferase
KGNHNLKD_01687 6.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KGNHNLKD_01688 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KGNHNLKD_01689 3.7e-122 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KGNHNLKD_01690 1.9e-47 yhbY J RNA-binding protein
KGNHNLKD_01691 5.8e-216 yqeH S Ribosome biogenesis GTPase YqeH
KGNHNLKD_01692 1.7e-96 yqeG S HAD phosphatase, family IIIA
KGNHNLKD_01693 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KGNHNLKD_01694 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KGNHNLKD_01695 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KGNHNLKD_01696 3.7e-171 dnaI L Primosomal protein DnaI
KGNHNLKD_01697 3e-227 dnaB L replication initiation and membrane attachment
KGNHNLKD_01698 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KGNHNLKD_01699 7.2e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KGNHNLKD_01700 7e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KGNHNLKD_01701 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KGNHNLKD_01702 1.4e-119 yoaK S Protein of unknown function (DUF1275)
KGNHNLKD_01703 2.1e-118 ybhL S Belongs to the BI1 family
KGNHNLKD_01704 2.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KGNHNLKD_01705 1.6e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KGNHNLKD_01706 3.3e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KGNHNLKD_01707 9.7e-58 ytzB S Small secreted protein
KGNHNLKD_01708 4.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
KGNHNLKD_01709 2.2e-179 iolS C Aldo keto reductase
KGNHNLKD_01710 1.6e-253 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KGNHNLKD_01711 1.8e-21 A chlorophyll binding
KGNHNLKD_01712 1.7e-81 A chlorophyll binding
KGNHNLKD_01713 2.9e-45 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
KGNHNLKD_01714 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KGNHNLKD_01715 6.3e-200 ecsB U ABC transporter
KGNHNLKD_01716 1e-136 ecsA V ABC transporter, ATP-binding protein
KGNHNLKD_01717 8.3e-78 hit FG histidine triad
KGNHNLKD_01719 3.5e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KGNHNLKD_01720 0.0 L AAA domain
KGNHNLKD_01721 1.2e-214 yhaO L Ser Thr phosphatase family protein
KGNHNLKD_01722 9.4e-38 yheA S Belongs to the UPF0342 family
KGNHNLKD_01723 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KGNHNLKD_01725 1.5e-258 xylT EGP Major facilitator Superfamily
KGNHNLKD_01726 1.6e-114 rhaS2 K Transcriptional regulator, AraC family
KGNHNLKD_01727 1.6e-49 rhaS2 K Transcriptional regulator, AraC family
KGNHNLKD_01728 1.6e-290 xynT G MFS/sugar transport protein
KGNHNLKD_01729 0.0 3.2.1.55 GH51 G Right handed beta helix region
KGNHNLKD_01730 6e-20 pgdA 3.5.1.104 G polysaccharide deacetylase
KGNHNLKD_01731 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
KGNHNLKD_01732 7.6e-271 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KGNHNLKD_01733 1.9e-302 xylB 2.7.1.17 G Belongs to the FGGY kinase family
KGNHNLKD_01734 1.2e-154 KT YcbB domain
KGNHNLKD_01735 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KGNHNLKD_01736 7.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
KGNHNLKD_01737 9.6e-161 EG EamA-like transporter family
KGNHNLKD_01738 7.7e-45 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KGNHNLKD_01739 1e-27 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KGNHNLKD_01740 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KGNHNLKD_01741 8.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KGNHNLKD_01742 0.0 copA 3.6.3.54 P P-type ATPase
KGNHNLKD_01743 1.3e-87
KGNHNLKD_01745 3.6e-57
KGNHNLKD_01746 2.1e-248 yjcE P Sodium proton antiporter
KGNHNLKD_01752 6.5e-14 arpU S Phage transcriptional regulator, ArpU family
KGNHNLKD_01753 9.5e-108 S D5 N terminal like
KGNHNLKD_01754 2.8e-47 S Bifunctional DNA primase/polymerase, N-terminal
KGNHNLKD_01756 3.3e-12
KGNHNLKD_01758 8.2e-14
KGNHNLKD_01759 1.2e-15 xre K sequence-specific DNA binding
KGNHNLKD_01760 1.5e-131 L Belongs to the 'phage' integrase family
KGNHNLKD_01761 1.3e-90
KGNHNLKD_01762 0.0 M domain protein
KGNHNLKD_01763 1.2e-18
KGNHNLKD_01764 2e-186 ampC V Beta-lactamase
KGNHNLKD_01765 1.6e-238 arcA 3.5.3.6 E Arginine
KGNHNLKD_01766 2.7e-79 argR K Regulates arginine biosynthesis genes
KGNHNLKD_01767 5.2e-262 E Arginine ornithine antiporter
KGNHNLKD_01768 1.2e-223 arcD U Amino acid permease
KGNHNLKD_01769 1.4e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KGNHNLKD_01770 1.3e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
KGNHNLKD_01771 4.6e-108 tdk 2.7.1.21 F thymidine kinase
KGNHNLKD_01772 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KGNHNLKD_01773 1.4e-164 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KGNHNLKD_01774 8e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KGNHNLKD_01775 4.6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KGNHNLKD_01776 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KGNHNLKD_01777 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KGNHNLKD_01778 2.9e-191 yibE S overlaps another CDS with the same product name
KGNHNLKD_01779 6.3e-129 yibF S overlaps another CDS with the same product name
KGNHNLKD_01780 6.5e-232 pyrP F Permease
KGNHNLKD_01781 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
KGNHNLKD_01782 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KGNHNLKD_01783 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KGNHNLKD_01784 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KGNHNLKD_01785 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KGNHNLKD_01786 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KGNHNLKD_01787 5.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KGNHNLKD_01788 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KGNHNLKD_01789 2.2e-33 ywzB S Protein of unknown function (DUF1146)
KGNHNLKD_01790 2.5e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KGNHNLKD_01791 5.5e-178 mbl D Cell shape determining protein MreB Mrl
KGNHNLKD_01792 1e-31 S Protein of unknown function (DUF2969)
KGNHNLKD_01793 1.1e-220 rodA D Belongs to the SEDS family
KGNHNLKD_01794 1.8e-47 gcvH E glycine cleavage
KGNHNLKD_01795 4.1e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KGNHNLKD_01796 9.6e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
KGNHNLKD_01797 8.3e-257 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KGNHNLKD_01798 2e-234 lmrB EGP Major facilitator Superfamily
KGNHNLKD_01799 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KGNHNLKD_01800 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KGNHNLKD_01801 7.1e-136 sufD O Uncharacterized protein family (UPF0051)
KGNHNLKD_01802 9.8e-40 lytE M LysM domain protein
KGNHNLKD_01803 0.0 oppD EP Psort location Cytoplasmic, score
KGNHNLKD_01804 2.3e-93 lytE M LysM domain protein
KGNHNLKD_01805 1.6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
KGNHNLKD_01806 5.8e-233 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KGNHNLKD_01807 1.3e-209 preA 1.3.1.1 C 4Fe-4S dicluster domain
KGNHNLKD_01809 1.7e-111 lssY 3.6.1.27 I Acid phosphatase homologues
KGNHNLKD_01810 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KGNHNLKD_01811 6.3e-227 clcA_2 P Chloride transporter, ClC family
KGNHNLKD_01812 4.7e-117 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KGNHNLKD_01813 8.7e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KGNHNLKD_01814 1.1e-139 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KGNHNLKD_01815 1.4e-50
KGNHNLKD_01816 0.0 S SEC-C Motif Domain Protein
KGNHNLKD_01817 5.8e-115 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KGNHNLKD_01818 2.7e-76
KGNHNLKD_01819 9.8e-180
KGNHNLKD_01820 1.3e-70 fecB P Periplasmic binding protein
KGNHNLKD_01821 2e-184 comP 2.7.13.3 F Sensor histidine kinase
KGNHNLKD_01822 8.8e-44
KGNHNLKD_01823 1.2e-103 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KGNHNLKD_01824 9.7e-83 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KGNHNLKD_01825 9.4e-228 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
KGNHNLKD_01826 6e-80 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KGNHNLKD_01827 3.9e-187 moeB 2.7.7.73, 2.7.7.80 H ThiF family
KGNHNLKD_01828 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KGNHNLKD_01829 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
KGNHNLKD_01830 1.9e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
KGNHNLKD_01831 1.5e-129 narI 1.7.5.1 C Nitrate reductase
KGNHNLKD_01832 8.5e-154 EG EamA-like transporter family
KGNHNLKD_01833 1.2e-117 L Integrase
KGNHNLKD_01834 1.9e-158 rssA S Phospholipase, patatin family
KGNHNLKD_01837 8.6e-264 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
KGNHNLKD_01838 1.3e-201 xerS L Belongs to the 'phage' integrase family
KGNHNLKD_01840 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KGNHNLKD_01841 1e-75 marR K Transcriptional regulator, MarR family
KGNHNLKD_01842 2.2e-29 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KGNHNLKD_01843 1.2e-123 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KGNHNLKD_01844 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KGNHNLKD_01845 7.2e-159 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KGNHNLKD_01846 1.4e-130 IQ reductase
KGNHNLKD_01847 3.4e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KGNHNLKD_01848 1.1e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KGNHNLKD_01849 7.3e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KGNHNLKD_01850 4.8e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KGNHNLKD_01851 8.7e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KGNHNLKD_01852 5.7e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KGNHNLKD_01853 5.3e-128 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KGNHNLKD_01862 6.7e-13
KGNHNLKD_01863 3.9e-170 M MucBP domain
KGNHNLKD_01864 1.9e-88
KGNHNLKD_01865 7.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KGNHNLKD_01866 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KGNHNLKD_01867 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KGNHNLKD_01868 4.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KGNHNLKD_01869 2.3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KGNHNLKD_01870 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KGNHNLKD_01871 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
KGNHNLKD_01872 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
KGNHNLKD_01873 4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KGNHNLKD_01874 3.1e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KGNHNLKD_01875 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KGNHNLKD_01876 3.5e-163 S Tetratricopeptide repeat
KGNHNLKD_01877 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KGNHNLKD_01878 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KGNHNLKD_01879 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
KGNHNLKD_01880 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KGNHNLKD_01881 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KGNHNLKD_01882 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
KGNHNLKD_01883 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KGNHNLKD_01884 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KGNHNLKD_01885 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KGNHNLKD_01886 4.1e-51 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KGNHNLKD_01887 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KGNHNLKD_01888 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KGNHNLKD_01889 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
KGNHNLKD_01890 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KGNHNLKD_01891 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KGNHNLKD_01892 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KGNHNLKD_01893 1.9e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KGNHNLKD_01894 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KGNHNLKD_01895 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KGNHNLKD_01896 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KGNHNLKD_01897 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KGNHNLKD_01898 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KGNHNLKD_01899 2.9e-24 rpmD J Ribosomal protein L30
KGNHNLKD_01900 5.8e-63 rplO J Binds to the 23S rRNA
KGNHNLKD_01901 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KGNHNLKD_01902 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KGNHNLKD_01903 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KGNHNLKD_01904 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KGNHNLKD_01905 3.6e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KGNHNLKD_01906 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KGNHNLKD_01907 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KGNHNLKD_01908 1.1e-62 rplQ J Ribosomal protein L17
KGNHNLKD_01909 3e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGNHNLKD_01910 4.1e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGNHNLKD_01911 2.8e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KGNHNLKD_01912 5.5e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KGNHNLKD_01913 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KGNHNLKD_01914 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KGNHNLKD_01915 1.2e-140 IQ reductase
KGNHNLKD_01916 1.4e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
KGNHNLKD_01917 5.1e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KGNHNLKD_01918 2.3e-212 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KGNHNLKD_01919 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KGNHNLKD_01920 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KGNHNLKD_01921 3.6e-202 camS S sex pheromone
KGNHNLKD_01922 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KGNHNLKD_01923 1.1e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KGNHNLKD_01924 2.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KGNHNLKD_01925 1.4e-184 yegS 2.7.1.107 G Lipid kinase
KGNHNLKD_01926 5.2e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KGNHNLKD_01927 1.5e-32 S Domain of unknown function (DUF4417)
KGNHNLKD_01928 2.9e-19
KGNHNLKD_01929 3e-23
KGNHNLKD_01930 1.7e-15 K Helix-turn-helix domain
KGNHNLKD_01931 1.1e-23 E Zn peptidase
KGNHNLKD_01933 1.3e-16
KGNHNLKD_01934 3.4e-266 pipD E Dipeptidase
KGNHNLKD_01935 4e-203 coiA 3.6.4.12 S Competence protein
KGNHNLKD_01936 3e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KGNHNLKD_01937 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KGNHNLKD_01938 2.3e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KGNHNLKD_01940 2e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KGNHNLKD_01941 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KGNHNLKD_01942 8.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KGNHNLKD_01943 3.3e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KGNHNLKD_01944 6.9e-228 mtnE 2.6.1.83 E Aminotransferase
KGNHNLKD_01945 6.2e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KGNHNLKD_01946 4.5e-309 uup S ABC transporter, ATP-binding protein
KGNHNLKD_01947 1.1e-81 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KGNHNLKD_01949 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KGNHNLKD_01950 2.1e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KGNHNLKD_01951 1.6e-32 S YbaK proline--tRNA ligase associated domain protein
KGNHNLKD_01952 1.6e-32 S Aminoacyl-tRNA editing domain
KGNHNLKD_01953 2.4e-303 ybeC E amino acid
KGNHNLKD_01954 0.0 ydaO E amino acid
KGNHNLKD_01955 3e-38
KGNHNLKD_01956 1.4e-107 yocS S SBF-like CPA transporter family (DUF4137)
KGNHNLKD_01957 1e-65 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KGNHNLKD_01958 6.8e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KGNHNLKD_01959 1.5e-138 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KGNHNLKD_01960 2.2e-36 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KGNHNLKD_01961 2.1e-208 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KGNHNLKD_01962 1.4e-204 ydiN G Major Facilitator Superfamily
KGNHNLKD_01963 1.4e-155 menH 2.2.1.9, 4.2.99.20, 6.2.1.26 I Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KGNHNLKD_01964 3.2e-248 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KGNHNLKD_01965 1.1e-250 menF 5.4.4.2 HQ chorismate binding enzyme
KGNHNLKD_01966 1.8e-58 S Uncharacterised protein family (UPF0236)
KGNHNLKD_01967 8e-53 yhaI S Protein of unknown function (DUF805)
KGNHNLKD_01968 1.3e-41 ybaN S Protein of unknown function (DUF454)
KGNHNLKD_01969 5.9e-71 S Protein of unknown function (DUF3290)
KGNHNLKD_01970 2e-68 yviA S Protein of unknown function (DUF421)
KGNHNLKD_01971 3.6e-165 S Alpha/beta hydrolase of unknown function (DUF915)
KGNHNLKD_01972 3.4e-21
KGNHNLKD_01973 1.2e-90 ntd 2.4.2.6 F Nucleoside
KGNHNLKD_01974 7.9e-154 3.1.3.102, 3.1.3.104 S hydrolase
KGNHNLKD_01975 1.8e-38 yrvD S Pfam:DUF1049
KGNHNLKD_01977 6.5e-57 L Helix-turn-helix domain
KGNHNLKD_01978 1.9e-56 L Helix-turn-helix domain
KGNHNLKD_01979 1.2e-70 L hmm pf00665
KGNHNLKD_01980 4.6e-73 L hmm pf00665
KGNHNLKD_01981 8.9e-16 XK27_13030
KGNHNLKD_01982 1.3e-162 I alpha/beta hydrolase fold
KGNHNLKD_01983 1.2e-112 frnE Q DSBA-like thioredoxin domain
KGNHNLKD_01984 1.4e-54
KGNHNLKD_01985 1.2e-114 yjbH Q Thioredoxin
KGNHNLKD_01986 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
KGNHNLKD_01987 3.9e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KGNHNLKD_01988 6.2e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
KGNHNLKD_01989 1.3e-147 yaaU EGP Major facilitator Superfamily
KGNHNLKD_01990 2.1e-43 mleP3 S Membrane transport protein
KGNHNLKD_01993 2.8e-07
KGNHNLKD_01994 1e-68 L PFAM transposase IS116 IS110 IS902
KGNHNLKD_01995 8.8e-62 L PFAM transposase IS116 IS110 IS902
KGNHNLKD_01998 2.3e-213 2.7.13.3 T GHKL domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)