ORF_ID e_value Gene_name EC_number CAZy COGs Description
BBHKPEMM_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BBHKPEMM_00002 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
BBHKPEMM_00003 1.1e-29 yyzM S Protein conserved in bacteria
BBHKPEMM_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
BBHKPEMM_00005 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
BBHKPEMM_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBHKPEMM_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
BBHKPEMM_00008 2.7e-61 divIC D Septum formation initiator
BBHKPEMM_00010 8.7e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
BBHKPEMM_00011 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
BBHKPEMM_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
BBHKPEMM_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBHKPEMM_00014 1.3e-137 L Transposase
BBHKPEMM_00015 7.3e-92 L Transposase
BBHKPEMM_00016 5.9e-55 L transposition
BBHKPEMM_00017 1.9e-86 L Integrase core domain protein
BBHKPEMM_00030 5.3e-11
BBHKPEMM_00036 5.5e-139 mreC M Involved in formation and maintenance of cell shape
BBHKPEMM_00037 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BBHKPEMM_00038 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
BBHKPEMM_00039 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBHKPEMM_00040 2.9e-218 araT 2.6.1.1 E Aminotransferase
BBHKPEMM_00041 2.6e-143 recO L Involved in DNA repair and RecF pathway recombination
BBHKPEMM_00042 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BBHKPEMM_00043 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBHKPEMM_00044 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
BBHKPEMM_00045 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBHKPEMM_00046 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BBHKPEMM_00047 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
BBHKPEMM_00048 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBHKPEMM_00049 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
BBHKPEMM_00050 6.1e-79 L transposase activity
BBHKPEMM_00051 1.3e-49 L transposition
BBHKPEMM_00052 6.3e-34 L Integrase core domain protein
BBHKPEMM_00053 2.3e-161 S CHAP domain
BBHKPEMM_00054 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
BBHKPEMM_00055 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBHKPEMM_00056 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BBHKPEMM_00057 9.2e-141 1.1.1.169 H Ketopantoate reductase
BBHKPEMM_00058 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBHKPEMM_00059 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
BBHKPEMM_00060 1.2e-09 L Transposase
BBHKPEMM_00061 7.8e-211 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BBHKPEMM_00062 8.3e-221 nodC 2.4.1.212 GT2 M Chitin synthase
BBHKPEMM_00063 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
BBHKPEMM_00064 3.5e-28 3.4.13.21 I Protein conserved in bacteria
BBHKPEMM_00067 1.3e-57 T Toxic component of a toxin-antitoxin (TA) module
BBHKPEMM_00069 8.2e-70 argR K Regulates arginine biosynthesis genes
BBHKPEMM_00070 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
BBHKPEMM_00071 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBHKPEMM_00072 7e-34 S Protein of unknown function (DUF3021)
BBHKPEMM_00073 1.2e-61 KT phosphorelay signal transduction system
BBHKPEMM_00075 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BBHKPEMM_00077 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
BBHKPEMM_00078 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
BBHKPEMM_00079 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
BBHKPEMM_00080 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BBHKPEMM_00081 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
BBHKPEMM_00087 2.6e-10
BBHKPEMM_00090 1.9e-07
BBHKPEMM_00095 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBHKPEMM_00096 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
BBHKPEMM_00097 5.5e-36 XK27_02060 S Transglycosylase associated protein
BBHKPEMM_00098 1.7e-54 badR K DNA-binding transcription factor activity
BBHKPEMM_00099 1e-96 S reductase
BBHKPEMM_00100 2.3e-31 L Integrase core domain protein
BBHKPEMM_00101 6.2e-36 L transposition
BBHKPEMM_00102 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
BBHKPEMM_00103 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
BBHKPEMM_00106 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
BBHKPEMM_00107 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BBHKPEMM_00108 1.1e-83 S Putative small multi-drug export protein
BBHKPEMM_00109 6.2e-76 ctsR K Belongs to the CtsR family
BBHKPEMM_00110 0.0 clpC O Belongs to the ClpA ClpB family
BBHKPEMM_00111 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BBHKPEMM_00112 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BBHKPEMM_00113 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BBHKPEMM_00114 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
BBHKPEMM_00115 6.9e-144 S SseB protein N-terminal domain
BBHKPEMM_00116 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
BBHKPEMM_00117 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
BBHKPEMM_00118 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BBHKPEMM_00121 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBHKPEMM_00122 1e-84 yacP S RNA-binding protein containing a PIN domain
BBHKPEMM_00123 3.4e-155 degV S DegV family
BBHKPEMM_00125 1.8e-31 K helix-turn-helix
BBHKPEMM_00126 6.1e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BBHKPEMM_00127 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBHKPEMM_00128 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
BBHKPEMM_00129 1.5e-35 K sequence-specific DNA binding
BBHKPEMM_00131 0.0 S Lantibiotic dehydratase, C terminus
BBHKPEMM_00132 2.4e-231 spaC2 V Lanthionine synthetase C family protein
BBHKPEMM_00133 4.3e-183 EGP Major facilitator Superfamily
BBHKPEMM_00134 5.9e-24 3.6.4.12
BBHKPEMM_00135 5.9e-91 3.6.4.12 K Divergent AAA domain protein
BBHKPEMM_00136 7.4e-225 int L Belongs to the 'phage' integrase family
BBHKPEMM_00137 1.8e-38 S Helix-turn-helix domain
BBHKPEMM_00138 4.9e-173
BBHKPEMM_00140 3.4e-75 isp2 S pathogenesis
BBHKPEMM_00141 5.7e-91 tnp L Transposase
BBHKPEMM_00142 3.3e-225 capA M Bacterial capsule synthesis protein
BBHKPEMM_00143 3.6e-39 gcvR T UPF0237 protein
BBHKPEMM_00144 1.9e-242 XK27_08635 S UPF0210 protein
BBHKPEMM_00145 2.2e-38 ais G alpha-ribazole phosphatase activity
BBHKPEMM_00146 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
BBHKPEMM_00147 1.3e-102 acmA 3.2.1.17 NU amidase activity
BBHKPEMM_00148 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BBHKPEMM_00149 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BBHKPEMM_00150 9.8e-298 dnaK O Heat shock 70 kDa protein
BBHKPEMM_00151 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BBHKPEMM_00152 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
BBHKPEMM_00153 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
BBHKPEMM_00154 1.7e-60 hmpT S membrane
BBHKPEMM_00157 0.0 amiA E ABC transporter, substrate-binding protein, family 5
BBHKPEMM_00158 6.5e-142 L Transposase
BBHKPEMM_00159 9.9e-19 S Domain of unknown function (DUF4649)
BBHKPEMM_00160 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
BBHKPEMM_00161 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
BBHKPEMM_00162 6.5e-87
BBHKPEMM_00163 1.6e-77 sigH K DNA-templated transcription, initiation
BBHKPEMM_00164 3.5e-149 ykuT M mechanosensitive ion channel
BBHKPEMM_00165 7.1e-218 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BBHKPEMM_00166 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
BBHKPEMM_00167 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
BBHKPEMM_00168 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
BBHKPEMM_00169 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
BBHKPEMM_00170 2e-177 prmA J Ribosomal protein L11 methyltransferase
BBHKPEMM_00171 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
BBHKPEMM_00172 1.4e-42 F nucleotide catabolic process
BBHKPEMM_00173 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BBHKPEMM_00174 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BBHKPEMM_00175 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BBHKPEMM_00176 1.8e-83 nrdI F Belongs to the NrdI family
BBHKPEMM_00177 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBHKPEMM_00178 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BBHKPEMM_00179 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
BBHKPEMM_00180 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
BBHKPEMM_00181 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
BBHKPEMM_00182 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
BBHKPEMM_00183 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBHKPEMM_00184 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BBHKPEMM_00185 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
BBHKPEMM_00186 6.5e-202 yhjX P Major Facilitator
BBHKPEMM_00187 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BBHKPEMM_00188 5e-94 V VanZ like family
BBHKPEMM_00189 1e-123 glnQ E abc transporter atp-binding protein
BBHKPEMM_00190 5.8e-275 glnP P ABC transporter
BBHKPEMM_00191 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
BBHKPEMM_00192 1.3e-134 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BBHKPEMM_00193 1.9e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
BBHKPEMM_00194 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
BBHKPEMM_00195 1.4e-234 sufD O assembly protein SufD
BBHKPEMM_00196 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBHKPEMM_00197 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
BBHKPEMM_00198 2.2e-273 sufB O assembly protein SufB
BBHKPEMM_00199 7e-10 oppA E ABC transporter substrate-binding protein
BBHKPEMM_00200 2e-138 oppA E ABC transporter substrate-binding protein
BBHKPEMM_00201 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBHKPEMM_00202 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBHKPEMM_00203 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBHKPEMM_00204 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBHKPEMM_00205 3e-27 oppD P Belongs to the ABC transporter superfamily
BBHKPEMM_00206 2.5e-32 oppD P Belongs to the ABC transporter superfamily
BBHKPEMM_00207 1.2e-62 oppD P Belongs to the ABC transporter superfamily
BBHKPEMM_00208 3.1e-43 oppD P Belongs to the ABC transporter superfamily
BBHKPEMM_00209 7.5e-62 oppF P Belongs to the ABC transporter superfamily
BBHKPEMM_00210 4.4e-62 oppF P Belongs to the ABC transporter superfamily
BBHKPEMM_00211 6.4e-23
BBHKPEMM_00212 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BBHKPEMM_00213 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBHKPEMM_00214 1.9e-223 EGP Major facilitator Superfamily
BBHKPEMM_00215 3.1e-72 adcR K transcriptional
BBHKPEMM_00216 2.2e-136 adcC P ABC transporter, ATP-binding protein
BBHKPEMM_00217 1.6e-127 adcB P ABC transporter (Permease
BBHKPEMM_00218 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
BBHKPEMM_00219 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
BBHKPEMM_00220 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
BBHKPEMM_00221 1.4e-105 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
BBHKPEMM_00222 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
BBHKPEMM_00223 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
BBHKPEMM_00224 1.9e-127 yeeN K transcriptional regulatory protein
BBHKPEMM_00225 9.8e-50 yajC U protein transport
BBHKPEMM_00226 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BBHKPEMM_00227 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
BBHKPEMM_00228 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
BBHKPEMM_00229 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
BBHKPEMM_00230 0.0 WQ51_06230 S ABC transporter substrate binding protein
BBHKPEMM_00231 5.2e-142 cmpC S abc transporter atp-binding protein
BBHKPEMM_00232 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BBHKPEMM_00233 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
BBHKPEMM_00234 4.4e-37 L Transposase
BBHKPEMM_00235 6.4e-18 L transposase activity
BBHKPEMM_00236 1.5e-30 L transposition
BBHKPEMM_00239 4.7e-43
BBHKPEMM_00240 6.8e-56 S TM2 domain
BBHKPEMM_00241 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BBHKPEMM_00242 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BBHKPEMM_00243 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BBHKPEMM_00244 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
BBHKPEMM_00245 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
BBHKPEMM_00246 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
BBHKPEMM_00247 6e-55 cof Q phosphatase activity
BBHKPEMM_00248 6.2e-35 cof Q phosphatase activity
BBHKPEMM_00249 1.6e-137 glcR K transcriptional regulator (DeoR family)
BBHKPEMM_00250 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
BBHKPEMM_00251 3.8e-40 K transcriptional
BBHKPEMM_00253 2.6e-76 S thiolester hydrolase activity
BBHKPEMM_00254 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
BBHKPEMM_00255 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BBHKPEMM_00256 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
BBHKPEMM_00257 1.9e-77 yhaI L Membrane
BBHKPEMM_00258 5.1e-259 pepC 3.4.22.40 E aminopeptidase
BBHKPEMM_00259 1.6e-249 L Transposase
BBHKPEMM_00260 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BBHKPEMM_00261 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
BBHKPEMM_00262 3.1e-95 ypsA S Belongs to the UPF0398 family
BBHKPEMM_00263 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
BBHKPEMM_00264 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
BBHKPEMM_00265 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
BBHKPEMM_00266 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
BBHKPEMM_00267 2.5e-23
BBHKPEMM_00268 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
BBHKPEMM_00269 7.3e-80 XK27_09675 K -acetyltransferase
BBHKPEMM_00270 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BBHKPEMM_00271 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BBHKPEMM_00272 5.2e-59 L Integrase core domain protein
BBHKPEMM_00273 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BBHKPEMM_00274 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
BBHKPEMM_00275 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBHKPEMM_00276 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
BBHKPEMM_00277 8.8e-98 ybhL S Belongs to the BI1 family
BBHKPEMM_00280 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
BBHKPEMM_00281 3.7e-91 K transcriptional regulator
BBHKPEMM_00282 7.6e-36 yneF S UPF0154 protein
BBHKPEMM_00283 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
BBHKPEMM_00284 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BBHKPEMM_00285 3.5e-99 XK27_09740 S Phosphoesterase
BBHKPEMM_00286 7.8e-85 ykuL S CBS domain
BBHKPEMM_00287 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
BBHKPEMM_00288 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BBHKPEMM_00289 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBHKPEMM_00290 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BBHKPEMM_00291 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
BBHKPEMM_00292 1.2e-258 trkH P Cation transport protein
BBHKPEMM_00293 1.5e-247 trkA P Potassium transporter peripheral membrane component
BBHKPEMM_00294 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BBHKPEMM_00295 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BBHKPEMM_00296 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
BBHKPEMM_00297 5.6e-161 K sequence-specific DNA binding
BBHKPEMM_00298 1.2e-32 V protein secretion by the type I secretion system
BBHKPEMM_00299 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BBHKPEMM_00300 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BBHKPEMM_00301 1.6e-25 V protein secretion by the type I secretion system
BBHKPEMM_00302 1.8e-27 comA V protein secretion by the type I secretion system
BBHKPEMM_00303 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BBHKPEMM_00304 3.7e-51 yhaI L Membrane
BBHKPEMM_00305 6.7e-36 S Domain of unknown function (DUF4173)
BBHKPEMM_00306 9.2e-132 S Domain of unknown function (DUF4173)
BBHKPEMM_00307 6.8e-95 ureI S AmiS/UreI family transporter
BBHKPEMM_00308 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
BBHKPEMM_00309 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
BBHKPEMM_00310 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
BBHKPEMM_00311 6.6e-78 ureE O enzyme active site formation
BBHKPEMM_00312 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BBHKPEMM_00313 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BBHKPEMM_00314 1.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BBHKPEMM_00315 2.7e-177 cbiM P PDGLE domain
BBHKPEMM_00316 1.1e-136 P cobalt transport protein
BBHKPEMM_00317 1.6e-131 cbiO P ABC transporter
BBHKPEMM_00318 5.3e-153 ET amino acid transport
BBHKPEMM_00319 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BBHKPEMM_00320 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
BBHKPEMM_00321 3.8e-205 EGP Transmembrane secretion effector
BBHKPEMM_00322 1.8e-153 ET amino acid transport
BBHKPEMM_00323 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
BBHKPEMM_00324 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
BBHKPEMM_00325 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
BBHKPEMM_00326 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
BBHKPEMM_00327 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBHKPEMM_00328 5.2e-98 metI P ABC transporter (Permease
BBHKPEMM_00329 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BBHKPEMM_00330 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
BBHKPEMM_00331 8e-94 S UPF0397 protein
BBHKPEMM_00332 0.0 ykoD P abc transporter atp-binding protein
BBHKPEMM_00333 1.2e-146 cbiQ P cobalt transport
BBHKPEMM_00334 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BBHKPEMM_00335 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
BBHKPEMM_00336 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
BBHKPEMM_00337 1.2e-244 P COG0168 Trk-type K transport systems, membrane components
BBHKPEMM_00338 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
BBHKPEMM_00339 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
BBHKPEMM_00340 3e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BBHKPEMM_00341 2.8e-282 T PhoQ Sensor
BBHKPEMM_00342 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBHKPEMM_00343 6.5e-218 dnaB L Replication initiation and membrane attachment
BBHKPEMM_00344 4.4e-166 dnaI L Primosomal protein DnaI
BBHKPEMM_00345 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
BBHKPEMM_00347 1.2e-34
BBHKPEMM_00348 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
BBHKPEMM_00349 3e-27 L Integrase core domain protein
BBHKPEMM_00350 3.4e-50 L transposition
BBHKPEMM_00351 5.7e-23 L Transposase
BBHKPEMM_00352 7.8e-28 L transposase activity
BBHKPEMM_00353 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BBHKPEMM_00354 4.2e-62 manO S protein conserved in bacteria
BBHKPEMM_00355 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
BBHKPEMM_00356 2.3e-116 manM G pts system
BBHKPEMM_00357 1.1e-181 manL 2.7.1.191 G pts system
BBHKPEMM_00358 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
BBHKPEMM_00359 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
BBHKPEMM_00360 1.9e-248 pbuO S permease
BBHKPEMM_00361 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
BBHKPEMM_00362 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
BBHKPEMM_00363 2.5e-220 brpA K Transcriptional
BBHKPEMM_00364 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
BBHKPEMM_00365 3.1e-212 nusA K Participates in both transcription termination and antitermination
BBHKPEMM_00366 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
BBHKPEMM_00367 2e-46 ylxQ J ribosomal protein
BBHKPEMM_00368 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BBHKPEMM_00369 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BBHKPEMM_00370 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
BBHKPEMM_00371 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
BBHKPEMM_00372 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
BBHKPEMM_00373 6.2e-85 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
BBHKPEMM_00374 3.2e-49 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
BBHKPEMM_00375 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBHKPEMM_00376 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
BBHKPEMM_00377 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
BBHKPEMM_00378 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
BBHKPEMM_00379 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
BBHKPEMM_00381 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BBHKPEMM_00382 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BBHKPEMM_00383 1.2e-74 ylbF S Belongs to the UPF0342 family
BBHKPEMM_00384 7.1e-46 ylbG S UPF0298 protein
BBHKPEMM_00385 1.3e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
BBHKPEMM_00386 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
BBHKPEMM_00387 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
BBHKPEMM_00388 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
BBHKPEMM_00389 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
BBHKPEMM_00390 6.8e-69 acuB S IMP dehydrogenase activity
BBHKPEMM_00391 8.9e-41 acuB S IMP dehydrogenase activity
BBHKPEMM_00392 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BBHKPEMM_00393 1.1e-110 yvyE 3.4.13.9 S YigZ family
BBHKPEMM_00394 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BBHKPEMM_00395 1.7e-122 comFC S Competence protein
BBHKPEMM_00396 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBHKPEMM_00404 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
BBHKPEMM_00405 6.4e-108 S Domain of unknown function (DUF1803)
BBHKPEMM_00406 7.8e-102 ygaC J Belongs to the UPF0374 family
BBHKPEMM_00407 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
BBHKPEMM_00408 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBHKPEMM_00409 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
BBHKPEMM_00410 2.6e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
BBHKPEMM_00411 1.9e-115 S Haloacid dehalogenase-like hydrolase
BBHKPEMM_00412 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
BBHKPEMM_00413 4e-72 marR K Transcriptional regulator, MarR family
BBHKPEMM_00414 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBHKPEMM_00415 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBHKPEMM_00416 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
BBHKPEMM_00417 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
BBHKPEMM_00418 1.6e-126 IQ reductase
BBHKPEMM_00419 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
BBHKPEMM_00420 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
BBHKPEMM_00421 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BBHKPEMM_00422 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
BBHKPEMM_00423 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BBHKPEMM_00424 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
BBHKPEMM_00425 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
BBHKPEMM_00426 1.1e-65 tnp L Transposase
BBHKPEMM_00427 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
BBHKPEMM_00428 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
BBHKPEMM_00429 4.7e-27 L Transposase and inactivated derivatives, TnpA family
BBHKPEMM_00430 3.4e-126 tnp L Transposase
BBHKPEMM_00432 8e-277 S Protein of unknown function (DUF3114)
BBHKPEMM_00433 2.2e-38 2.3.1.128 K Acetyltransferase GNAT Family
BBHKPEMM_00434 7.7e-198 V (ABC) transporter
BBHKPEMM_00435 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
BBHKPEMM_00436 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
BBHKPEMM_00437 1.1e-113 K sequence-specific DNA binding
BBHKPEMM_00438 8.4e-155 L COG2801 Transposase and inactivated derivatives
BBHKPEMM_00439 6.6e-38 L transposase activity
BBHKPEMM_00440 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
BBHKPEMM_00441 1.8e-84 L Transposase
BBHKPEMM_00442 5.5e-122 fruR K transcriptional
BBHKPEMM_00443 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
BBHKPEMM_00444 0.0 fruA 2.7.1.202 G phosphotransferase system
BBHKPEMM_00445 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBHKPEMM_00446 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BBHKPEMM_00448 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
BBHKPEMM_00449 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBHKPEMM_00450 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
BBHKPEMM_00451 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
BBHKPEMM_00452 6.4e-29 2.3.1.128 K acetyltransferase
BBHKPEMM_00453 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
BBHKPEMM_00454 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
BBHKPEMM_00455 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBHKPEMM_00456 2.6e-64 WQ51_03320 S cog cog4835
BBHKPEMM_00457 9.8e-91 XK27_08360 S EDD domain protein, DegV family
BBHKPEMM_00458 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
BBHKPEMM_00459 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BBHKPEMM_00460 0.0 yfmR S abc transporter atp-binding protein
BBHKPEMM_00461 1.6e-24 U response to pH
BBHKPEMM_00462 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
BBHKPEMM_00463 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
BBHKPEMM_00464 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
BBHKPEMM_00465 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
BBHKPEMM_00466 1.9e-77 K DNA-binding transcription factor activity
BBHKPEMM_00467 0.0 lmrA1 V abc transporter atp-binding protein
BBHKPEMM_00468 0.0 lmrA2 V abc transporter atp-binding protein
BBHKPEMM_00469 5.4e-45 K Acetyltransferase (GNAT) family
BBHKPEMM_00470 3.2e-78 sptS 2.7.13.3 T Histidine kinase
BBHKPEMM_00471 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
BBHKPEMM_00472 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BBHKPEMM_00473 5.3e-161 cvfB S Protein conserved in bacteria
BBHKPEMM_00474 7.4e-35 yozE S Belongs to the UPF0346 family
BBHKPEMM_00475 2.9e-124 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
BBHKPEMM_00476 2.3e-61 rlpA M LysM domain protein
BBHKPEMM_00477 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
BBHKPEMM_00481 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBHKPEMM_00482 1.8e-164 K transcriptional regulator (lysR family)
BBHKPEMM_00483 1.4e-186 coiA 3.6.4.12 S Competence protein
BBHKPEMM_00484 0.0 pepF E oligoendopeptidase F
BBHKPEMM_00485 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
BBHKPEMM_00486 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
BBHKPEMM_00487 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BBHKPEMM_00488 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
BBHKPEMM_00489 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
BBHKPEMM_00490 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
BBHKPEMM_00491 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
BBHKPEMM_00492 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
BBHKPEMM_00493 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BBHKPEMM_00494 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BBHKPEMM_00495 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
BBHKPEMM_00496 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
BBHKPEMM_00497 2.2e-130 yxkH G deacetylase
BBHKPEMM_00498 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
BBHKPEMM_00499 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BBHKPEMM_00500 5.5e-153 rarD S Transporter
BBHKPEMM_00501 2.2e-15 T peptidase
BBHKPEMM_00502 8.9e-14 coiA 3.6.4.12 S Competence protein
BBHKPEMM_00503 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BBHKPEMM_00504 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBHKPEMM_00505 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
BBHKPEMM_00506 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBHKPEMM_00507 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
BBHKPEMM_00508 3.3e-78 atpF C ATP synthase F(0) sector subunit b
BBHKPEMM_00509 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBHKPEMM_00510 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BBHKPEMM_00511 7.4e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BBHKPEMM_00512 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BBHKPEMM_00513 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
BBHKPEMM_00514 2.8e-230 ftsW D Belongs to the SEDS family
BBHKPEMM_00515 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBHKPEMM_00516 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BBHKPEMM_00517 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BBHKPEMM_00518 1.9e-161 holB 2.7.7.7 L dna polymerase iii
BBHKPEMM_00519 2.1e-135 yaaT S stage 0 sporulation protein
BBHKPEMM_00520 9.5e-55 yabA L Involved in initiation control of chromosome replication
BBHKPEMM_00521 3.9e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BBHKPEMM_00522 7.5e-233 amt P Ammonium Transporter
BBHKPEMM_00523 1.1e-53 glnB K Belongs to the P(II) protein family
BBHKPEMM_00524 4.9e-106 mur1 NU mannosyl-glycoprotein
BBHKPEMM_00525 1.7e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
BBHKPEMM_00526 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
BBHKPEMM_00527 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBHKPEMM_00528 1.8e-53
BBHKPEMM_00529 7.5e-26
BBHKPEMM_00530 1.5e-59
BBHKPEMM_00531 6.1e-63 S membrane
BBHKPEMM_00532 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
BBHKPEMM_00533 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
BBHKPEMM_00534 4.5e-39 ynzC S UPF0291 protein
BBHKPEMM_00535 1.8e-254 cycA E permease
BBHKPEMM_00536 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
BBHKPEMM_00537 2.8e-24 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBHKPEMM_00538 5.8e-71 pts33BCA G pts system
BBHKPEMM_00539 9e-96 pts33BCA G pts system
BBHKPEMM_00540 9.7e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
BBHKPEMM_00541 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBHKPEMM_00542 1.2e-165 L integrase core domain
BBHKPEMM_00543 3.9e-122 L Transposase
BBHKPEMM_00548 1.4e-167 fhuR K transcriptional regulator (lysR family)
BBHKPEMM_00549 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BBHKPEMM_00550 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BBHKPEMM_00551 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BBHKPEMM_00552 4.9e-227 pyrP F uracil Permease
BBHKPEMM_00553 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
BBHKPEMM_00554 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
BBHKPEMM_00555 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
BBHKPEMM_00556 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
BBHKPEMM_00557 4e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBHKPEMM_00558 1.6e-33 V permease protein
BBHKPEMM_00559 1e-09 V permease protein
BBHKPEMM_00560 8.8e-21 V permease protein
BBHKPEMM_00561 1.7e-07 V efflux transmembrane transporter activity
BBHKPEMM_00562 1.1e-24 ytrF V efflux transmembrane transporter activity
BBHKPEMM_00563 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BBHKPEMM_00564 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
BBHKPEMM_00565 8.8e-223 L Transposase
BBHKPEMM_00567 0.0 mdlB V abc transporter atp-binding protein
BBHKPEMM_00568 0.0 lmrA V abc transporter atp-binding protein
BBHKPEMM_00569 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BBHKPEMM_00570 5.8e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BBHKPEMM_00571 6.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
BBHKPEMM_00572 2.5e-132 rr02 KT response regulator
BBHKPEMM_00573 3.5e-202 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
BBHKPEMM_00574 4.8e-168 V ABC transporter
BBHKPEMM_00575 5.4e-122 sagI S ABC-2 type transporter
BBHKPEMM_00576 4.5e-196 yceA S Belongs to the UPF0176 family
BBHKPEMM_00577 8e-28 XK27_00085 K Transcriptional
BBHKPEMM_00578 1.7e-23
BBHKPEMM_00579 1.2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
BBHKPEMM_00580 2.8e-112 S VIT family
BBHKPEMM_00581 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BBHKPEMM_00582 2.4e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
BBHKPEMM_00583 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
BBHKPEMM_00584 2e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
BBHKPEMM_00585 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBHKPEMM_00586 8.8e-104 GBS0088 J protein conserved in bacteria
BBHKPEMM_00587 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
BBHKPEMM_00588 1.5e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
BBHKPEMM_00589 1.6e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
BBHKPEMM_00590 7.6e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
BBHKPEMM_00591 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBHKPEMM_00592 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
BBHKPEMM_00593 2.5e-21
BBHKPEMM_00594 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBHKPEMM_00596 3.5e-07 U protein secretion
BBHKPEMM_00597 2.5e-51 U protein secretion
BBHKPEMM_00598 7.4e-08 M Pilin isopeptide linkage domain protein
BBHKPEMM_00599 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
BBHKPEMM_00600 1.5e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
BBHKPEMM_00601 3.5e-49 XK27_13030
BBHKPEMM_00602 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BBHKPEMM_00603 8.3e-55 S hydrolase activity, acting on ester bonds
BBHKPEMM_00604 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
BBHKPEMM_00605 6.8e-164 S Protein of unknown function (DUF3114)
BBHKPEMM_00606 1.2e-22 S Protein of unknown function (DUF3114)
BBHKPEMM_00607 1.5e-118 yqfA K protein, Hemolysin III
BBHKPEMM_00608 1e-25 K hmm pf08876
BBHKPEMM_00609 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
BBHKPEMM_00610 1.7e-218 mvaS 2.3.3.10 I synthase
BBHKPEMM_00611 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BBHKPEMM_00612 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBHKPEMM_00613 9.7e-22
BBHKPEMM_00614 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BBHKPEMM_00615 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
BBHKPEMM_00616 1.5e-250 mmuP E amino acid
BBHKPEMM_00617 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
BBHKPEMM_00618 1.4e-29 S Domain of unknown function (DUF1912)
BBHKPEMM_00619 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
BBHKPEMM_00620 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BBHKPEMM_00621 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BBHKPEMM_00622 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BBHKPEMM_00623 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
BBHKPEMM_00624 4.8e-16 S Protein of unknown function (DUF2969)
BBHKPEMM_00627 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
BBHKPEMM_00630 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
BBHKPEMM_00631 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
BBHKPEMM_00632 3.7e-70 M Pfam SNARE associated Golgi protein
BBHKPEMM_00633 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
BBHKPEMM_00634 1.6e-08 S oxidoreductase
BBHKPEMM_00635 9.3e-59 S oxidoreductase
BBHKPEMM_00636 9.7e-66 S oxidoreductase
BBHKPEMM_00637 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
BBHKPEMM_00638 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
BBHKPEMM_00639 0.0 clpE O Belongs to the ClpA ClpB family
BBHKPEMM_00640 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBHKPEMM_00641 1.3e-34 ykuJ S protein conserved in bacteria
BBHKPEMM_00642 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
BBHKPEMM_00643 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
BBHKPEMM_00644 3.1e-78 feoA P FeoA domain protein
BBHKPEMM_00645 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
BBHKPEMM_00646 1.5e-07
BBHKPEMM_00647 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
BBHKPEMM_00648 2.2e-45 K sequence-specific DNA binding
BBHKPEMM_00649 1.5e-35 yugF I carboxylic ester hydrolase activity
BBHKPEMM_00650 7.5e-23 I Alpha/beta hydrolase family
BBHKPEMM_00651 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BBHKPEMM_00652 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BBHKPEMM_00653 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
BBHKPEMM_00654 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BBHKPEMM_00655 5.8e-64 licT K transcriptional antiterminator
BBHKPEMM_00656 6.8e-53 licT K transcriptional antiterminator
BBHKPEMM_00657 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BBHKPEMM_00658 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
BBHKPEMM_00659 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBHKPEMM_00660 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
BBHKPEMM_00661 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BBHKPEMM_00662 2.5e-220 mdtG EGP Major facilitator Superfamily
BBHKPEMM_00663 2e-33 secG U Preprotein translocase subunit SecG
BBHKPEMM_00664 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BBHKPEMM_00665 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
BBHKPEMM_00666 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBHKPEMM_00667 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
BBHKPEMM_00668 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
BBHKPEMM_00669 4.4e-183 ccpA K Catabolite control protein A
BBHKPEMM_00670 2.8e-28 yyaQ S YjbR
BBHKPEMM_00671 6.6e-101 yyaQ V Protein conserved in bacteria
BBHKPEMM_00672 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
BBHKPEMM_00673 1e-78 yueI S Protein of unknown function (DUF1694)
BBHKPEMM_00674 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BBHKPEMM_00675 2e-25 WQ51_00785
BBHKPEMM_00676 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
BBHKPEMM_00677 2e-219 ywbD 2.1.1.191 J Methyltransferase
BBHKPEMM_00678 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
BBHKPEMM_00679 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBHKPEMM_00680 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BBHKPEMM_00681 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BBHKPEMM_00682 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
BBHKPEMM_00683 3.2e-53 yheA S Belongs to the UPF0342 family
BBHKPEMM_00684 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
BBHKPEMM_00685 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
BBHKPEMM_00686 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BBHKPEMM_00687 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
BBHKPEMM_00688 6.4e-252 msrR K Transcriptional regulator
BBHKPEMM_00689 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
BBHKPEMM_00690 2.4e-203 I acyl-CoA dehydrogenase
BBHKPEMM_00691 4.5e-97 mip S hydroperoxide reductase activity
BBHKPEMM_00692 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBHKPEMM_00693 8.9e-20
BBHKPEMM_00694 3.2e-46
BBHKPEMM_00695 1e-31 K Cro/C1-type HTH DNA-binding domain
BBHKPEMM_00696 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
BBHKPEMM_00697 9.7e-34 estA E GDSL-like Lipase/Acylhydrolase
BBHKPEMM_00698 1.1e-94
BBHKPEMM_00699 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BBHKPEMM_00700 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBHKPEMM_00701 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBHKPEMM_00702 2.6e-194 S CRISPR-associated protein Csn2 subfamily St
BBHKPEMM_00703 2.7e-146 ycgQ S TIGR03943 family
BBHKPEMM_00704 4.6e-155 XK27_03015 S permease
BBHKPEMM_00706 0.0 yhgF K Transcriptional accessory protein
BBHKPEMM_00707 9.9e-42 pspC KT PspC domain
BBHKPEMM_00708 2e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BBHKPEMM_00709 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BBHKPEMM_00711 5.5e-69 ytxH S General stress protein
BBHKPEMM_00713 2e-177 yegQ O Peptidase U32
BBHKPEMM_00714 3.4e-252 yegQ O Peptidase U32
BBHKPEMM_00715 8.1e-46 S CHY zinc finger
BBHKPEMM_00716 8.4e-88 bioY S biotin synthase
BBHKPEMM_00718 1.1e-33 XK27_12190 S protein conserved in bacteria
BBHKPEMM_00719 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
BBHKPEMM_00720 4.8e-11
BBHKPEMM_00721 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
BBHKPEMM_00722 4.1e-225 mutH L DNA mismatch repair enzyme MutH
BBHKPEMM_00723 5.2e-29 S SIR2-like domain
BBHKPEMM_00724 1.2e-33 S SIR2-like domain
BBHKPEMM_00725 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
BBHKPEMM_00726 6.4e-158 M LysM domain
BBHKPEMM_00727 7.6e-16
BBHKPEMM_00728 2.3e-175 S hydrolase
BBHKPEMM_00729 1.9e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
BBHKPEMM_00730 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBHKPEMM_00731 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
BBHKPEMM_00732 2.7e-27 P Hemerythrin HHE cation binding domain protein
BBHKPEMM_00733 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBHKPEMM_00734 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
BBHKPEMM_00735 3.9e-290 hsdM 2.1.1.72 V N-6 DNA Methylase
BBHKPEMM_00736 2.2e-147 3.1.21.3 V type I restriction modification DNA specificity domain
BBHKPEMM_00738 2.5e-44
BBHKPEMM_00739 3e-38
BBHKPEMM_00740 2.3e-171 spd F DNA RNA non-specific endonuclease
BBHKPEMM_00741 1.5e-92 lemA S LemA family
BBHKPEMM_00742 1.8e-135 htpX O Belongs to the peptidase M48B family
BBHKPEMM_00743 4.2e-75 S Psort location CytoplasmicMembrane, score
BBHKPEMM_00744 6.2e-56 S Domain of unknown function (DUF4430)
BBHKPEMM_00745 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BBHKPEMM_00746 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
BBHKPEMM_00747 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
BBHKPEMM_00748 2.7e-160 L Transposase
BBHKPEMM_00749 3e-50 L Transposase
BBHKPEMM_00750 2.6e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
BBHKPEMM_00751 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
BBHKPEMM_00752 3.5e-91 dps P Belongs to the Dps family
BBHKPEMM_00753 1.1e-80 perR P Belongs to the Fur family
BBHKPEMM_00754 8.4e-28 yqgQ S protein conserved in bacteria
BBHKPEMM_00755 2.2e-179 glk 2.7.1.2 G Glucokinase
BBHKPEMM_00756 0.0 typA T GTP-binding protein TypA
BBHKPEMM_00758 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBHKPEMM_00759 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBHKPEMM_00760 1.8e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
BBHKPEMM_00761 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
BBHKPEMM_00762 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBHKPEMM_00763 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBHKPEMM_00764 6.8e-96 sepF D cell septum assembly
BBHKPEMM_00765 2.6e-34 yggT D integral membrane protein
BBHKPEMM_00766 4.2e-144 ylmH T S4 RNA-binding domain
BBHKPEMM_00767 1.8e-135 divIVA D Cell division protein DivIVA
BBHKPEMM_00768 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BBHKPEMM_00769 5.5e-30
BBHKPEMM_00770 8.4e-10
BBHKPEMM_00771 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
BBHKPEMM_00772 2e-45 rpmE2 J 50S ribosomal protein L31
BBHKPEMM_00773 8.3e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
BBHKPEMM_00774 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
BBHKPEMM_00775 8.9e-155 gst O Glutathione S-transferase
BBHKPEMM_00776 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BBHKPEMM_00777 4.5e-111 tdk 2.7.1.21 F thymidine kinase
BBHKPEMM_00778 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BBHKPEMM_00779 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BBHKPEMM_00780 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BBHKPEMM_00781 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BBHKPEMM_00782 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
BBHKPEMM_00783 8e-100 pvaA M lytic transglycosylase activity
BBHKPEMM_00784 0.0 yfiB1 V abc transporter atp-binding protein
BBHKPEMM_00785 0.0 XK27_10035 V abc transporter atp-binding protein
BBHKPEMM_00786 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
BBHKPEMM_00787 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BBHKPEMM_00788 3.9e-237 dltB M Membrane protein involved in D-alanine export
BBHKPEMM_00789 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BBHKPEMM_00790 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BBHKPEMM_00791 4.5e-233 L Transposase
BBHKPEMM_00792 9.8e-32 L Integrase core domain protein
BBHKPEMM_00793 9.6e-32 L transposition
BBHKPEMM_00794 6.5e-54 L transposition
BBHKPEMM_00795 7.7e-19 L transposase activity
BBHKPEMM_00796 2.5e-40 L Transposase
BBHKPEMM_00797 0.0 3.6.3.8 P cation transport ATPase
BBHKPEMM_00798 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
BBHKPEMM_00799 1.9e-105 V Abi-like protein
BBHKPEMM_00801 2.3e-12
BBHKPEMM_00803 2e-296 S DNA primase
BBHKPEMM_00804 3e-164 KL Phage plasmid primase P4 family
BBHKPEMM_00805 2.4e-22
BBHKPEMM_00806 1.2e-14
BBHKPEMM_00810 1.8e-19 K Cro/C1-type HTH DNA-binding domain
BBHKPEMM_00811 1e-21 xre K transcriptional
BBHKPEMM_00812 6.9e-220 sip L Belongs to the 'phage' integrase family
BBHKPEMM_00814 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BBHKPEMM_00815 7.3e-166 metF 1.5.1.20 E reductase
BBHKPEMM_00816 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
BBHKPEMM_00817 1.7e-94 panT S ECF transporter, substrate-specific component
BBHKPEMM_00818 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBHKPEMM_00819 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
BBHKPEMM_00820 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
BBHKPEMM_00821 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BBHKPEMM_00822 2.8e-40 T PhoQ Sensor
BBHKPEMM_00823 1.7e-43 T PhoQ Sensor
BBHKPEMM_00824 5.8e-79 T PhoQ Sensor
BBHKPEMM_00825 6.7e-122 L Helix-turn-helix domain
BBHKPEMM_00826 1.2e-165 L integrase core domain
BBHKPEMM_00827 2.1e-30 rpsT J rRNA binding
BBHKPEMM_00828 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
BBHKPEMM_00829 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
BBHKPEMM_00830 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
BBHKPEMM_00831 6e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
BBHKPEMM_00832 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBHKPEMM_00833 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBHKPEMM_00834 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
BBHKPEMM_00835 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
BBHKPEMM_00836 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
BBHKPEMM_00837 4e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
BBHKPEMM_00838 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
BBHKPEMM_00839 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
BBHKPEMM_00840 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
BBHKPEMM_00841 3.1e-81 ypmB S Protein conserved in bacteria
BBHKPEMM_00842 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
BBHKPEMM_00843 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
BBHKPEMM_00844 1.5e-07
BBHKPEMM_00845 2.4e-30
BBHKPEMM_00846 3e-13
BBHKPEMM_00847 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
BBHKPEMM_00848 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BBHKPEMM_00849 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
BBHKPEMM_00850 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
BBHKPEMM_00851 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
BBHKPEMM_00852 4.2e-18 D nuclear chromosome segregation
BBHKPEMM_00853 1.5e-135 yejC S cyclic nucleotide-binding protein
BBHKPEMM_00854 1.2e-163 rapZ S Displays ATPase and GTPase activities
BBHKPEMM_00855 1.8e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
BBHKPEMM_00856 8.7e-162 whiA K May be required for sporulation
BBHKPEMM_00857 8e-90 pepD E Dipeptidase
BBHKPEMM_00858 5.8e-41 pepD E dipeptidase activity
BBHKPEMM_00859 5.4e-32 cspD K Cold shock protein domain
BBHKPEMM_00860 1.6e-249 L Transposase
BBHKPEMM_00861 9.4e-43 K Cold-Shock Protein
BBHKPEMM_00862 3e-113 L Transposase, Mutator family
BBHKPEMM_00863 4.3e-26 L Transposase
BBHKPEMM_00864 1.7e-44 L Transposase
BBHKPEMM_00865 0.0 copB 3.6.3.4 P P-type ATPase
BBHKPEMM_00866 1.6e-88 L Transposase
BBHKPEMM_00867 6.6e-94 L Transposase
BBHKPEMM_00868 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
BBHKPEMM_00869 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BBHKPEMM_00870 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
BBHKPEMM_00871 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
BBHKPEMM_00872 4.1e-220 L Transposase
BBHKPEMM_00873 4.8e-157 glcU U Glucose uptake
BBHKPEMM_00874 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
BBHKPEMM_00875 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
BBHKPEMM_00876 2.2e-101 XK27_10720 D peptidase activity
BBHKPEMM_00877 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
BBHKPEMM_00878 1.7e-08
BBHKPEMM_00880 1.2e-172 yeiH S Membrane
BBHKPEMM_00881 5.5e-119 mur1 NU muramidase
BBHKPEMM_00882 1.9e-83 L transposition
BBHKPEMM_00883 2.6e-166 cpsY K Transcriptional regulator
BBHKPEMM_00884 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
BBHKPEMM_00885 1.2e-57 phnA P Alkylphosphonate utilization operon protein PhnA
BBHKPEMM_00886 2e-104 artQ P ABC transporter (Permease
BBHKPEMM_00887 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
BBHKPEMM_00888 1.1e-158 aatB ET ABC transporter substrate-binding protein
BBHKPEMM_00889 3.5e-40 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBHKPEMM_00890 2.5e-139 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBHKPEMM_00891 1.7e-57 adhP 1.1.1.1 C alcohol dehydrogenase
BBHKPEMM_00892 1.3e-106 adhP 1.1.1.1 C alcohol dehydrogenase
BBHKPEMM_00893 9.3e-20 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
BBHKPEMM_00894 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
BBHKPEMM_00895 4.5e-126 gntR1 K transcriptional
BBHKPEMM_00896 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BBHKPEMM_00897 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBHKPEMM_00898 4.1e-87 niaX
BBHKPEMM_00899 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
BBHKPEMM_00900 6.9e-127 K DNA-binding helix-turn-helix protein
BBHKPEMM_00901 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BBHKPEMM_00902 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBHKPEMM_00903 4.1e-167 GK ROK family
BBHKPEMM_00904 8.3e-159 dprA LU DNA protecting protein DprA
BBHKPEMM_00905 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBHKPEMM_00906 1.4e-150 S TraX protein
BBHKPEMM_00907 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BBHKPEMM_00908 2.4e-251 T PhoQ Sensor
BBHKPEMM_00909 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BBHKPEMM_00910 1.1e-152 XK27_05470 E Methionine synthase
BBHKPEMM_00911 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
BBHKPEMM_00912 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBHKPEMM_00913 1.8e-51 IQ Acetoin reductase
BBHKPEMM_00914 6.6e-19 IQ Acetoin reductase
BBHKPEMM_00915 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BBHKPEMM_00916 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
BBHKPEMM_00919 1.3e-212 pqqE C radical SAM domain protein
BBHKPEMM_00920 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
BBHKPEMM_00921 6.6e-61 EGP Major facilitator Superfamily
BBHKPEMM_00922 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
BBHKPEMM_00923 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
BBHKPEMM_00924 5.2e-201 L Transposase
BBHKPEMM_00925 6.4e-104 V ABC transporter (Permease
BBHKPEMM_00926 4.1e-114 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
BBHKPEMM_00927 1.6e-10
BBHKPEMM_00928 1.2e-103 K Transcriptional regulator, TetR family
BBHKPEMM_00929 1.2e-158 czcD P cation diffusion facilitator family transporter
BBHKPEMM_00930 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
BBHKPEMM_00931 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
BBHKPEMM_00932 6e-08 S Hydrolases of the alpha beta superfamily
BBHKPEMM_00933 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
BBHKPEMM_00934 3.8e-78 S Alpha/beta hydrolase of unknown function (DUF915)
BBHKPEMM_00935 1.6e-249 L Transposase
BBHKPEMM_00938 2.6e-143 2.4.2.3 F Phosphorylase superfamily
BBHKPEMM_00939 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
BBHKPEMM_00940 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
BBHKPEMM_00941 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
BBHKPEMM_00942 6.6e-73 dinF V Mate efflux family protein
BBHKPEMM_00943 4.8e-41 dinF V Mate efflux family protein
BBHKPEMM_00945 2.3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
BBHKPEMM_00946 3.7e-190
BBHKPEMM_00947 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
BBHKPEMM_00948 3.5e-28 3.4.13.21 I Protein conserved in bacteria
BBHKPEMM_00950 5.7e-118 S TraX protein
BBHKPEMM_00951 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
BBHKPEMM_00952 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
BBHKPEMM_00953 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
BBHKPEMM_00954 4.7e-143 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBHKPEMM_00955 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBHKPEMM_00956 6.8e-133 cas6 S Pfam:DUF2276
BBHKPEMM_00957 0.0 csm1 S CRISPR-associated protein Csm1 family
BBHKPEMM_00958 5.6e-62 csm2 L Pfam:DUF310
BBHKPEMM_00959 1.1e-116 csm3 L RAMP superfamily
BBHKPEMM_00960 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
BBHKPEMM_00961 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
BBHKPEMM_00962 2.1e-14 csm6 S Psort location Cytoplasmic, score
BBHKPEMM_00963 5.2e-74 csm6 S Psort location Cytoplasmic, score
BBHKPEMM_00964 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
BBHKPEMM_00965 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BBHKPEMM_00966 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
BBHKPEMM_00968 2.5e-267 dtpT E transporter
BBHKPEMM_00969 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
BBHKPEMM_00970 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
BBHKPEMM_00971 1.8e-67 yecS P ABC transporter (Permease
BBHKPEMM_00973 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
BBHKPEMM_00974 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
BBHKPEMM_00975 5.4e-104 yfiF3 K sequence-specific DNA binding
BBHKPEMM_00976 1.9e-147 L Transposase
BBHKPEMM_00977 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBHKPEMM_00978 1.8e-240 agcS E (Alanine) symporter
BBHKPEMM_00979 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
BBHKPEMM_00980 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
BBHKPEMM_00981 1.8e-59 Q phosphatase activity
BBHKPEMM_00982 9.3e-62 S haloacid dehalogenase-like hydrolase
BBHKPEMM_00983 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BBHKPEMM_00984 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
BBHKPEMM_00985 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
BBHKPEMM_00986 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
BBHKPEMM_00987 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BBHKPEMM_00988 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
BBHKPEMM_00989 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BBHKPEMM_00990 1.9e-43 yktA S Belongs to the UPF0223 family
BBHKPEMM_00991 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
BBHKPEMM_00992 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
BBHKPEMM_00993 3.3e-158 pstS P phosphate
BBHKPEMM_00994 1.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
BBHKPEMM_00995 2e-155 pstA P phosphate transport system permease
BBHKPEMM_00996 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BBHKPEMM_00997 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BBHKPEMM_00998 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
BBHKPEMM_00999 0.0 pepN 3.4.11.2 E aminopeptidase
BBHKPEMM_01000 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
BBHKPEMM_01001 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
BBHKPEMM_01002 1.1e-17
BBHKPEMM_01003 3.7e-09
BBHKPEMM_01004 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
BBHKPEMM_01005 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
BBHKPEMM_01006 2.3e-23 L Transposase
BBHKPEMM_01007 4.6e-25 tatA U protein secretion
BBHKPEMM_01008 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBHKPEMM_01009 1.1e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
BBHKPEMM_01010 5.6e-233 ycdB P peroxidase
BBHKPEMM_01011 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
BBHKPEMM_01012 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBHKPEMM_01013 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBHKPEMM_01014 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBHKPEMM_01015 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBHKPEMM_01016 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBHKPEMM_01017 1.9e-37 3.5.1.28 NU amidase activity
BBHKPEMM_01018 8.5e-266 3.5.1.28 NU amidase activity
BBHKPEMM_01019 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
BBHKPEMM_01020 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
BBHKPEMM_01021 0.0 lpdA 1.8.1.4 C Dehydrogenase
BBHKPEMM_01022 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
BBHKPEMM_01023 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
BBHKPEMM_01024 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
BBHKPEMM_01025 5e-38 P membrane protein (DUF2207)
BBHKPEMM_01026 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
BBHKPEMM_01027 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BBHKPEMM_01028 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BBHKPEMM_01029 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBHKPEMM_01030 1.2e-157 rssA S Phospholipase, patatin family
BBHKPEMM_01031 3.9e-78 estA E GDSL-like protein
BBHKPEMM_01032 2.6e-15 estA E Lysophospholipase L1 and related esterases
BBHKPEMM_01033 3.7e-293 S unusual protein kinase
BBHKPEMM_01034 4.9e-39 S granule-associated protein
BBHKPEMM_01035 7.9e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BBHKPEMM_01036 5.8e-28 bglH 3.2.1.86 GT1 G beta-glucosidase activity
BBHKPEMM_01037 1.3e-199 S hmm pf01594
BBHKPEMM_01038 1.6e-44 G alpha-ribazole phosphatase activity
BBHKPEMM_01039 2e-33 G Belongs to the phosphoglycerate mutase family
BBHKPEMM_01040 1.1e-25 G Belongs to the phosphoglycerate mutase family
BBHKPEMM_01041 8.8e-66 pgm G Belongs to the phosphoglycerate mutase family
BBHKPEMM_01042 1.7e-80 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
BBHKPEMM_01043 4.9e-94 V VanZ like family
BBHKPEMM_01044 8.1e-23 L Transposase
BBHKPEMM_01045 3.2e-92 L Transposase
BBHKPEMM_01046 6.4e-33 cpsJ S Glycosyltransferase like family 2
BBHKPEMM_01047 3e-15
BBHKPEMM_01048 1.1e-71 M Glycosyltransferase sugar-binding region containing DXD motif
BBHKPEMM_01049 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
BBHKPEMM_01050 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
BBHKPEMM_01051 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
BBHKPEMM_01052 3.3e-37 L transposase activity
BBHKPEMM_01053 4e-60 L COG2801 Transposase and inactivated derivatives
BBHKPEMM_01054 2.4e-30 tra981A L Integrase core domain
BBHKPEMM_01055 8.1e-52 tnp L DDE domain
BBHKPEMM_01056 1.4e-235 cps1C S Polysaccharide biosynthesis protein
BBHKPEMM_01057 9.1e-110 L Transposase
BBHKPEMM_01058 2.4e-93 L Transposase
BBHKPEMM_01059 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
BBHKPEMM_01060 3e-139 L Integrase core domain
BBHKPEMM_01061 2.2e-22 L Transposase
BBHKPEMM_01062 1.7e-27 tnp L DDE domain
BBHKPEMM_01063 8.5e-23 rgpAc GT4 M group 1 family protein
BBHKPEMM_01064 5.7e-250 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
BBHKPEMM_01065 5.3e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
BBHKPEMM_01066 2.6e-105 cps4C M biosynthesis protein
BBHKPEMM_01067 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
BBHKPEMM_01068 3.8e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
BBHKPEMM_01069 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
BBHKPEMM_01070 1.7e-48 yfeJ 6.3.5.2 F glutamine amidotransferase
BBHKPEMM_01071 2.5e-43 yfeJ 6.3.5.2 F glutamine amidotransferase
BBHKPEMM_01072 3.6e-40 clcA_2 P chloride
BBHKPEMM_01073 3.8e-42 clcA_2 P chloride channel
BBHKPEMM_01074 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BBHKPEMM_01075 9.3e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
BBHKPEMM_01076 6.6e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BBHKPEMM_01078 4e-21 V Glucan-binding protein C
BBHKPEMM_01079 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
BBHKPEMM_01080 2.4e-275 pepV 3.5.1.18 E Dipeptidase
BBHKPEMM_01081 3.2e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
BBHKPEMM_01082 6.9e-86 XK27_03610 K Gnat family
BBHKPEMM_01083 9.1e-10 L COG1943 Transposase and inactivated derivatives
BBHKPEMM_01084 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BBHKPEMM_01085 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
BBHKPEMM_01086 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBHKPEMM_01087 2.8e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
BBHKPEMM_01088 3.9e-15 M LysM domain
BBHKPEMM_01089 2.9e-90 ebsA S Family of unknown function (DUF5322)
BBHKPEMM_01090 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
BBHKPEMM_01091 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BBHKPEMM_01092 4.9e-224 G COG0457 FOG TPR repeat
BBHKPEMM_01093 1.1e-175 yubA S permease
BBHKPEMM_01094 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
BBHKPEMM_01095 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
BBHKPEMM_01096 2.5e-124 ftsE D cell division ATP-binding protein FtsE
BBHKPEMM_01097 1.8e-181 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBHKPEMM_01098 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BBHKPEMM_01099 4.3e-180 yjjH S Calcineurin-like phosphoesterase
BBHKPEMM_01100 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
BBHKPEMM_01101 0.0 pacL 3.6.3.8 P cation transport ATPase
BBHKPEMM_01102 2.6e-67 ywiB S Domain of unknown function (DUF1934)
BBHKPEMM_01103 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
BBHKPEMM_01104 9.2e-147 yidA S hydrolases of the HAD superfamily
BBHKPEMM_01105 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
BBHKPEMM_01106 5e-35 F Protein of unknown function (DUF454)
BBHKPEMM_01107 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
BBHKPEMM_01108 1.5e-247 vicK 2.7.13.3 T Histidine kinase
BBHKPEMM_01109 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BBHKPEMM_01110 1e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
BBHKPEMM_01111 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
BBHKPEMM_01112 8e-115 gltJ P ABC transporter (Permease
BBHKPEMM_01113 4.2e-110 tcyB_2 P ABC transporter (permease)
BBHKPEMM_01114 1.4e-124 endA F DNA RNA non-specific endonuclease
BBHKPEMM_01115 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
BBHKPEMM_01116 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBHKPEMM_01118 3.7e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BBHKPEMM_01119 4.9e-21 G Domain of unknown function (DUF4832)
BBHKPEMM_01120 8.4e-53 G Domain of unknown function (DUF4832)
BBHKPEMM_01121 1.5e-211 cotH M CotH kinase protein
BBHKPEMM_01122 6.8e-185 pelG M Putative exopolysaccharide Exporter (EPS-E)
BBHKPEMM_01123 1.9e-109 pelF GT4 M Domain of unknown function (DUF3492)
BBHKPEMM_01124 7.6e-160 pelF GT4 M Domain of unknown function (DUF3492)
BBHKPEMM_01125 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
BBHKPEMM_01126 4.1e-143
BBHKPEMM_01127 7.6e-134 5.1.3.2 GM Psort location CytoplasmicMembrane, score
BBHKPEMM_01128 2.9e-196 L Transposase
BBHKPEMM_01129 2.2e-63 L Transposase
BBHKPEMM_01130 1.2e-88 L Transposase
BBHKPEMM_01131 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BBHKPEMM_01132 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
BBHKPEMM_01133 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBHKPEMM_01134 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
BBHKPEMM_01135 1.9e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBHKPEMM_01136 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
BBHKPEMM_01138 7.7e-35
BBHKPEMM_01141 7.8e-202 S Phage integrase family
BBHKPEMM_01143 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BBHKPEMM_01144 4.3e-133 XK27_05110 P chloride
BBHKPEMM_01145 1.2e-61 XK27_05110 P chloride
BBHKPEMM_01146 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
BBHKPEMM_01147 1.3e-282 clcA P Chloride transporter, ClC family
BBHKPEMM_01148 6.7e-75 fld C Flavodoxin
BBHKPEMM_01150 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
BBHKPEMM_01151 3.5e-151 estA CE1 S Putative esterase
BBHKPEMM_01152 1e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBHKPEMM_01153 1.2e-135 XK27_08845 S abc transporter atp-binding protein
BBHKPEMM_01154 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
BBHKPEMM_01155 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
BBHKPEMM_01156 3.2e-17 S Domain of unknown function (DUF4649)
BBHKPEMM_01158 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
BBHKPEMM_01159 1.1e-22 Q the current gene model (or a revised gene model) may contain a frame shift
BBHKPEMM_01160 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
BBHKPEMM_01161 8.8e-223 L Transposase
BBHKPEMM_01163 1.6e-249 L Transposase
BBHKPEMM_01164 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
BBHKPEMM_01165 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
BBHKPEMM_01166 0.0 dnaE 2.7.7.7 L DNA polymerase
BBHKPEMM_01167 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
BBHKPEMM_01168 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBHKPEMM_01169 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBHKPEMM_01170 2.5e-43 ysdA L Membrane
BBHKPEMM_01171 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
BBHKPEMM_01172 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBHKPEMM_01173 3e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BBHKPEMM_01174 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
BBHKPEMM_01176 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BBHKPEMM_01177 1.7e-83 ypmS S Protein conserved in bacteria
BBHKPEMM_01178 6e-144 ypmR E lipolytic protein G-D-S-L family
BBHKPEMM_01179 1e-148 DegV S DegV family
BBHKPEMM_01180 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
BBHKPEMM_01181 1.8e-72 argR K Regulates arginine biosynthesis genes
BBHKPEMM_01182 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
BBHKPEMM_01183 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BBHKPEMM_01184 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
BBHKPEMM_01185 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BBHKPEMM_01188 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBHKPEMM_01189 2.9e-125 dnaD
BBHKPEMM_01190 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BBHKPEMM_01191 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBHKPEMM_01192 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
BBHKPEMM_01193 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BBHKPEMM_01194 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BBHKPEMM_01195 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
BBHKPEMM_01196 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBHKPEMM_01197 1.6e-239 rodA D Belongs to the SEDS family
BBHKPEMM_01198 4.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
BBHKPEMM_01199 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BBHKPEMM_01200 1.9e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
BBHKPEMM_01201 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BBHKPEMM_01202 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BBHKPEMM_01203 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
BBHKPEMM_01204 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BBHKPEMM_01205 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
BBHKPEMM_01206 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BBHKPEMM_01207 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBHKPEMM_01209 4.2e-86 L Integrase core domain protein
BBHKPEMM_01210 1.1e-53 L transposition
BBHKPEMM_01211 1.8e-21 L Transposase
BBHKPEMM_01212 5.2e-36 L transposase activity
BBHKPEMM_01213 1.3e-22 XK27_08085
BBHKPEMM_01214 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
BBHKPEMM_01215 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
BBHKPEMM_01216 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
BBHKPEMM_01217 1.1e-121 ylfI S tigr01906
BBHKPEMM_01218 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
BBHKPEMM_01219 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
BBHKPEMM_01220 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
BBHKPEMM_01223 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
BBHKPEMM_01224 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
BBHKPEMM_01225 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BBHKPEMM_01226 1.1e-206 yurR 1.4.5.1 E oxidoreductase
BBHKPEMM_01227 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
BBHKPEMM_01228 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBHKPEMM_01229 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
BBHKPEMM_01230 1.7e-70 gtrA S GtrA-like protein
BBHKPEMM_01231 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBHKPEMM_01232 6e-169 ybbR S Protein conserved in bacteria
BBHKPEMM_01233 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BBHKPEMM_01234 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
BBHKPEMM_01235 8.7e-150 cobQ S glutamine amidotransferase
BBHKPEMM_01236 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BBHKPEMM_01237 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
BBHKPEMM_01238 0.0 uup S abc transporter atp-binding protein
BBHKPEMM_01239 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
BBHKPEMM_01240 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
BBHKPEMM_01241 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
BBHKPEMM_01242 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
BBHKPEMM_01243 6.2e-249 L Transposase
BBHKPEMM_01244 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBHKPEMM_01245 7.9e-39 ptsH G phosphocarrier protein Hpr
BBHKPEMM_01246 3.3e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
BBHKPEMM_01247 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
BBHKPEMM_01248 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BBHKPEMM_01249 2.2e-34 nrdH O Glutaredoxin
BBHKPEMM_01250 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBHKPEMM_01251 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBHKPEMM_01253 4.2e-71 L Transposase (IS116 IS110 IS902 family)
BBHKPEMM_01254 3.3e-26 L Transposase (IS116 IS110 IS902 family)
BBHKPEMM_01255 1.2e-164 ypuA S secreted protein
BBHKPEMM_01256 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
BBHKPEMM_01257 5.1e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
BBHKPEMM_01258 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBHKPEMM_01259 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BBHKPEMM_01260 3.4e-258 noxE P NADH oxidase
BBHKPEMM_01261 1.9e-294 yfmM S abc transporter atp-binding protein
BBHKPEMM_01262 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
BBHKPEMM_01263 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
BBHKPEMM_01264 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
BBHKPEMM_01265 2e-86 S ECF-type riboflavin transporter, S component
BBHKPEMM_01267 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BBHKPEMM_01268 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
BBHKPEMM_01271 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BBHKPEMM_01272 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BBHKPEMM_01273 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BBHKPEMM_01274 0.0 smc D Required for chromosome condensation and partitioning
BBHKPEMM_01275 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BBHKPEMM_01276 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBHKPEMM_01277 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BBHKPEMM_01278 2.4e-92 pat 2.3.1.183 M acetyltransferase
BBHKPEMM_01279 1.1e-12
BBHKPEMM_01280 8.9e-30
BBHKPEMM_01281 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBHKPEMM_01282 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
BBHKPEMM_01283 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
BBHKPEMM_01284 1.2e-62 bioY S biotin transmembrane transporter activity
BBHKPEMM_01285 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
BBHKPEMM_01286 1.5e-138 proV E abc transporter atp-binding protein
BBHKPEMM_01287 4.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
BBHKPEMM_01288 3e-111 proWZ P ABC transporter (Permease
BBHKPEMM_01289 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
BBHKPEMM_01290 1.6e-205 S Protein of unknown function (DUF917)
BBHKPEMM_01291 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BBHKPEMM_01292 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
BBHKPEMM_01293 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BBHKPEMM_01294 1.5e-192 desK 2.7.13.3 T Histidine kinase
BBHKPEMM_01295 1.4e-133 yvfS V ABC-2 type transporter
BBHKPEMM_01296 8.7e-159 XK27_09825 V abc transporter atp-binding protein
BBHKPEMM_01299 8.1e-163 yocS S Transporter
BBHKPEMM_01300 1.2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
BBHKPEMM_01301 7.5e-115 yvfS V Transporter
BBHKPEMM_01302 3.9e-151 XK27_09825 V abc transporter atp-binding protein
BBHKPEMM_01303 2.7e-14 liaI KT membrane
BBHKPEMM_01304 2.6e-30 liaI KT membrane
BBHKPEMM_01305 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
BBHKPEMM_01306 0.0 V ABC transporter (permease)
BBHKPEMM_01307 1.9e-133 macB2 V ABC transporter, ATP-binding protein
BBHKPEMM_01308 3.1e-165 T Histidine kinase
BBHKPEMM_01309 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BBHKPEMM_01310 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
BBHKPEMM_01311 3.3e-69 pbuX F xanthine permease
BBHKPEMM_01312 9.2e-119 pbuX F xanthine permease
BBHKPEMM_01313 1.5e-247 norM V Multidrug efflux pump
BBHKPEMM_01314 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBHKPEMM_01315 1.3e-235 brnQ E Component of the transport system for branched-chain amino acids
BBHKPEMM_01316 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
BBHKPEMM_01317 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
BBHKPEMM_01318 4.8e-25 csbD K CsbD-like
BBHKPEMM_01319 6.2e-228 yfnA E amino acid
BBHKPEMM_01320 5.1e-110 XK27_02070 S nitroreductase
BBHKPEMM_01321 9.5e-150 1.13.11.2 S glyoxalase
BBHKPEMM_01322 5.6e-77 ywnA K Transcriptional regulator
BBHKPEMM_01323 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
BBHKPEMM_01324 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BBHKPEMM_01325 1.4e-110 drgA C Nitroreductase
BBHKPEMM_01326 3e-102 yoaK S Protein of unknown function (DUF1275)
BBHKPEMM_01328 6.8e-161 yvgN C reductase
BBHKPEMM_01329 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BBHKPEMM_01330 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
BBHKPEMM_01332 1.1e-37 BP1961 P nitric oxide dioxygenase activity
BBHKPEMM_01333 1.4e-54 K response regulator
BBHKPEMM_01334 9.3e-72 S Signal peptide protein, YSIRK family
BBHKPEMM_01336 4.5e-61
BBHKPEMM_01337 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBHKPEMM_01338 1e-137
BBHKPEMM_01339 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
BBHKPEMM_01340 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
BBHKPEMM_01341 5.8e-109 MA20_06410 E LysE type translocator
BBHKPEMM_01342 5.6e-08
BBHKPEMM_01343 2.7e-09
BBHKPEMM_01344 0.0 M family 8
BBHKPEMM_01346 1.5e-162 hrtB V MacB-like periplasmic core domain
BBHKPEMM_01347 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
BBHKPEMM_01348 1.1e-151 V MatE
BBHKPEMM_01350 3.9e-110 C Fe-S oxidoreductases
BBHKPEMM_01351 1.2e-176 EGP Major Facilitator Superfamily
BBHKPEMM_01352 5.5e-258 I radical SAM domain protein
BBHKPEMM_01354 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
BBHKPEMM_01355 1.4e-150 L Integrase core domain protein
BBHKPEMM_01356 1.8e-87 L transposase activity
BBHKPEMM_01358 2.8e-85
BBHKPEMM_01359 0.0 sbcC L ATPase involved in DNA repair
BBHKPEMM_01360 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
BBHKPEMM_01361 0.0 lacL 3.2.1.23 G -beta-galactosidase
BBHKPEMM_01362 0.0 lacS G transporter
BBHKPEMM_01363 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
BBHKPEMM_01364 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BBHKPEMM_01365 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
BBHKPEMM_01366 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BBHKPEMM_01367 2.3e-184 galR K Transcriptional regulator
BBHKPEMM_01368 2.7e-08 L Integrase core domain protein
BBHKPEMM_01369 1.2e-25 L transposition
BBHKPEMM_01370 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
BBHKPEMM_01371 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
BBHKPEMM_01372 2.5e-101 V abc transporter atp-binding protein
BBHKPEMM_01373 4.3e-40 V abc transporter atp-binding protein
BBHKPEMM_01374 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
BBHKPEMM_01375 6.4e-62 L Transposase
BBHKPEMM_01376 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBHKPEMM_01377 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBHKPEMM_01378 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBHKPEMM_01379 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
BBHKPEMM_01380 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
BBHKPEMM_01381 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
BBHKPEMM_01382 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BBHKPEMM_01385 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BBHKPEMM_01386 5.8e-175 vraS 2.7.13.3 T Histidine kinase
BBHKPEMM_01387 3.7e-120 yvqF KT membrane
BBHKPEMM_01388 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
BBHKPEMM_01389 2e-132 stp 3.1.3.16 T phosphatase
BBHKPEMM_01390 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBHKPEMM_01391 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BBHKPEMM_01392 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBHKPEMM_01393 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
BBHKPEMM_01394 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
BBHKPEMM_01395 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BBHKPEMM_01396 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
BBHKPEMM_01397 2.1e-148 supH S overlaps another CDS with the same product name
BBHKPEMM_01398 8.6e-63 yvoA_1 K Transcriptional
BBHKPEMM_01399 2.8e-120 skfE V abc transporter atp-binding protein
BBHKPEMM_01400 3.3e-133 V ATPase activity
BBHKPEMM_01401 4.3e-172 oppF P Belongs to the ABC transporter superfamily
BBHKPEMM_01402 2.2e-204 oppD P Belongs to the ABC transporter superfamily
BBHKPEMM_01403 4.9e-168 amiD P ABC transporter (Permease
BBHKPEMM_01404 4.2e-278 amiC P ABC transporter (Permease
BBHKPEMM_01405 0.0 amiA E ABC transporter, substrate-binding protein, family 5
BBHKPEMM_01406 1.5e-65
BBHKPEMM_01407 1.7e-123 L Transposase
BBHKPEMM_01408 0.0 amiA E ABC transporter, substrate-binding protein, family 5
BBHKPEMM_01409 8.1e-45 L Transposase
BBHKPEMM_01410 4.1e-158 L COG2801 Transposase and inactivated derivatives
BBHKPEMM_01411 1.2e-24 oppF P Belongs to the ABC transporter superfamily
BBHKPEMM_01412 3.8e-45 oppF P Belongs to the ABC transporter superfamily
BBHKPEMM_01413 1.4e-40 tatD L Hydrolase, tatd
BBHKPEMM_01414 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
BBHKPEMM_01415 1e-110 L Integrase core domain protein
BBHKPEMM_01416 1.1e-23 L transposase activity
BBHKPEMM_01417 8.9e-18 L transposase activity
BBHKPEMM_01418 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
BBHKPEMM_01419 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
BBHKPEMM_01420 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BBHKPEMM_01421 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
BBHKPEMM_01422 1.5e-103 yjbK S Adenylate cyclase
BBHKPEMM_01423 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBHKPEMM_01424 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
BBHKPEMM_01425 2e-58 XK27_04120 S Putative amino acid metabolism
BBHKPEMM_01426 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BBHKPEMM_01427 1.6e-131 puuD T peptidase C26
BBHKPEMM_01428 6.2e-120 radC E Belongs to the UPF0758 family
BBHKPEMM_01429 4.9e-272 rgpF M Rhamnan synthesis protein F
BBHKPEMM_01430 9e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
BBHKPEMM_01431 6.4e-140 rgpC GM Transport permease protein
BBHKPEMM_01432 2e-169 rgpB GT2 M Glycosyltransferase, group 2 family protein
BBHKPEMM_01433 1.1e-222 rgpA GT4 M Domain of unknown function (DUF1972)
BBHKPEMM_01434 5e-174 S Glucosyl transferase GtrII
BBHKPEMM_01435 1.8e-28 S Glucosyl transferase GtrII
BBHKPEMM_01436 1.6e-219 GT4 M transferase activity, transferring glycosyl groups
BBHKPEMM_01437 2e-217 M Psort location CytoplasmicMembrane, score
BBHKPEMM_01438 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
BBHKPEMM_01439 5.9e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
BBHKPEMM_01440 4.6e-42 S Uncharacterized conserved protein (DUF2304)
BBHKPEMM_01441 4.5e-129 arnC M group 2 family protein
BBHKPEMM_01442 1.1e-181 cpsIaJ S Glycosyltransferase like family 2
BBHKPEMM_01443 1e-184 S Glycosyltransferase like family 2
BBHKPEMM_01444 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
BBHKPEMM_01445 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
BBHKPEMM_01446 2.9e-235 S Predicted membrane protein (DUF2142)
BBHKPEMM_01447 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
BBHKPEMM_01448 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
BBHKPEMM_01449 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BBHKPEMM_01450 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BBHKPEMM_01451 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
BBHKPEMM_01452 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
BBHKPEMM_01453 2.1e-202 arcT 2.6.1.1 E Aminotransferase
BBHKPEMM_01454 9.4e-136 ET ABC transporter
BBHKPEMM_01455 1.1e-142 ET Belongs to the bacterial solute-binding protein 3 family
BBHKPEMM_01456 2.9e-84 mutT 3.6.1.55 F Nudix family
BBHKPEMM_01457 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
BBHKPEMM_01459 1.2e-55 V CAAX protease self-immunity
BBHKPEMM_01460 2.6e-32 S CAAX amino terminal protease family protein
BBHKPEMM_01461 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
BBHKPEMM_01462 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
BBHKPEMM_01463 2.4e-16 XK27_00735
BBHKPEMM_01464 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBHKPEMM_01466 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BBHKPEMM_01469 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
BBHKPEMM_01470 6.6e-30 ycaO O OsmC-like protein
BBHKPEMM_01472 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
BBHKPEMM_01474 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
BBHKPEMM_01475 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBHKPEMM_01476 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBHKPEMM_01477 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BBHKPEMM_01478 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
BBHKPEMM_01479 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BBHKPEMM_01480 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBHKPEMM_01481 2.6e-109 3.1.3.18 S IA, variant 1
BBHKPEMM_01482 2.2e-117 lrgB M effector of murein hydrolase
BBHKPEMM_01483 2.2e-58 lrgA S Effector of murein hydrolase LrgA
BBHKPEMM_01485 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
BBHKPEMM_01486 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
BBHKPEMM_01487 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBHKPEMM_01488 3.9e-104 wecD M Acetyltransferase GNAT family
BBHKPEMM_01489 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BBHKPEMM_01490 5.1e-96 GK ROK family
BBHKPEMM_01491 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
BBHKPEMM_01492 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
BBHKPEMM_01493 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
BBHKPEMM_01494 2.3e-206 potD P spermidine putrescine ABC transporter
BBHKPEMM_01495 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
BBHKPEMM_01496 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
BBHKPEMM_01497 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
BBHKPEMM_01498 7.8e-171 murB 1.3.1.98 M cell wall formation
BBHKPEMM_01499 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBHKPEMM_01500 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BBHKPEMM_01501 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
BBHKPEMM_01502 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BBHKPEMM_01503 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
BBHKPEMM_01504 0.0 ydaO E amino acid
BBHKPEMM_01505 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BBHKPEMM_01506 4.1e-37 ylqC L Belongs to the UPF0109 family
BBHKPEMM_01507 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
BBHKPEMM_01508 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
BBHKPEMM_01509 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
BBHKPEMM_01510 2.1e-74 S QueT transporter
BBHKPEMM_01511 1.9e-55 L Transposase
BBHKPEMM_01512 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
BBHKPEMM_01513 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBHKPEMM_01514 3.7e-85 ccl S cog cog4708
BBHKPEMM_01515 7.4e-164 rbn E Belongs to the UPF0761 family
BBHKPEMM_01516 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
BBHKPEMM_01517 3.3e-231 ytoI K transcriptional regulator containing CBS domains
BBHKPEMM_01518 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
BBHKPEMM_01519 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBHKPEMM_01520 0.0 comEC S Competence protein ComEC
BBHKPEMM_01521 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
BBHKPEMM_01522 1.3e-142 plsC 2.3.1.51 I Acyltransferase
BBHKPEMM_01523 1.7e-77 nodB3 G polysaccharide deacetylase
BBHKPEMM_01524 4.1e-22 nodB3 G polysaccharide deacetylase
BBHKPEMM_01525 2.3e-139 yabB 2.1.1.223 L Methyltransferase
BBHKPEMM_01526 1e-41 yazA L endonuclease containing a URI domain
BBHKPEMM_01527 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
BBHKPEMM_01528 2.3e-154 corA P CorA-like protein
BBHKPEMM_01529 1.9e-62 yjqA S Bacterial PH domain
BBHKPEMM_01530 7.8e-100 thiT S Thiamine transporter
BBHKPEMM_01531 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
BBHKPEMM_01532 1.9e-201 yjbB G Permeases of the major facilitator superfamily
BBHKPEMM_01533 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BBHKPEMM_01534 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
BBHKPEMM_01535 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
BBHKPEMM_01539 1.1e-155 cjaA ET ABC transporter substrate-binding protein
BBHKPEMM_01540 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
BBHKPEMM_01541 3e-106 P ABC transporter (Permease
BBHKPEMM_01542 6e-115 papP P ABC transporter (Permease
BBHKPEMM_01543 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
BBHKPEMM_01544 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
BBHKPEMM_01545 0.0 copA 3.6.3.54 P P-type ATPase
BBHKPEMM_01546 2.7e-73 copY K Copper transport repressor, CopY TcrY family
BBHKPEMM_01547 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
BBHKPEMM_01548 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BBHKPEMM_01549 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
BBHKPEMM_01550 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
BBHKPEMM_01551 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBHKPEMM_01552 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
BBHKPEMM_01553 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BBHKPEMM_01554 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
BBHKPEMM_01555 3.2e-56
BBHKPEMM_01556 0.0 ctpE P E1-E2 ATPase
BBHKPEMM_01557 2e-25
BBHKPEMM_01558 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BBHKPEMM_01559 9.7e-28 L transposase activity
BBHKPEMM_01560 2.7e-129 K transcriptional regulator, MerR family
BBHKPEMM_01561 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
BBHKPEMM_01562 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
BBHKPEMM_01563 7.4e-64 XK27_02560 S cog cog2151
BBHKPEMM_01564 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
BBHKPEMM_01565 7.7e-227 ytfP S Flavoprotein
BBHKPEMM_01567 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
BBHKPEMM_01568 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
BBHKPEMM_01569 2.7e-183 ecsB U ABC transporter
BBHKPEMM_01570 2.3e-133 ecsA V abc transporter atp-binding protein
BBHKPEMM_01571 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
BBHKPEMM_01572 5.6e-12
BBHKPEMM_01573 2.6e-55 S CD20-like family
BBHKPEMM_01574 2.1e-106
BBHKPEMM_01576 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
BBHKPEMM_01577 6.9e-206 ylbM S Belongs to the UPF0348 family
BBHKPEMM_01578 2e-140 yqeM Q Methyltransferase domain protein
BBHKPEMM_01579 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
BBHKPEMM_01580 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
BBHKPEMM_01581 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBHKPEMM_01582 3.5e-49 yhbY J RNA-binding protein
BBHKPEMM_01583 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
BBHKPEMM_01584 1.8e-98 yqeG S hydrolase of the HAD superfamily
BBHKPEMM_01585 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
BBHKPEMM_01586 1.3e-57
BBHKPEMM_01587 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBHKPEMM_01588 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
BBHKPEMM_01589 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBHKPEMM_01590 1.8e-23 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
BBHKPEMM_01591 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
BBHKPEMM_01592 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BBHKPEMM_01593 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BBHKPEMM_01594 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBHKPEMM_01595 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
BBHKPEMM_01596 6.8e-101 pncA Q isochorismatase
BBHKPEMM_01597 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BBHKPEMM_01598 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
BBHKPEMM_01599 2.4e-75 XK27_03180 T universal stress protein
BBHKPEMM_01602 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBHKPEMM_01603 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
BBHKPEMM_01604 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
BBHKPEMM_01605 0.0 yjcE P NhaP-type Na H and K H antiporters
BBHKPEMM_01607 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
BBHKPEMM_01608 1.3e-184 yhcC S radical SAM protein
BBHKPEMM_01609 2.2e-196 ylbL T Belongs to the peptidase S16 family
BBHKPEMM_01610 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBHKPEMM_01611 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
BBHKPEMM_01612 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
BBHKPEMM_01613 1.5e-09 S Protein of unknown function (DUF4059)
BBHKPEMM_01614 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
BBHKPEMM_01615 4.7e-163 yxeN P ABC transporter (Permease
BBHKPEMM_01616 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
BBHKPEMM_01618 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBHKPEMM_01619 0.0 pflB 2.3.1.54 C formate acetyltransferase'
BBHKPEMM_01620 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
BBHKPEMM_01621 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BBHKPEMM_01622 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
BBHKPEMM_01623 2.9e-87 D nuclear chromosome segregation
BBHKPEMM_01624 1.5e-127 ybbM S transport system, permease component
BBHKPEMM_01625 1.2e-117 ybbL S abc transporter atp-binding protein
BBHKPEMM_01626 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
BBHKPEMM_01627 4.6e-140 cppA E CppA N-terminal
BBHKPEMM_01628 5e-44 V CAAX protease self-immunity
BBHKPEMM_01629 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
BBHKPEMM_01630 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
BBHKPEMM_01633 3e-47 spiA K sequence-specific DNA binding
BBHKPEMM_01634 2.9e-28 blpT
BBHKPEMM_01635 6.7e-98 blpT
BBHKPEMM_01636 3.9e-122 L Transposase
BBHKPEMM_01637 1.2e-165 L integrase core domain
BBHKPEMM_01642 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
BBHKPEMM_01645 8.9e-133 agrA KT phosphorelay signal transduction system
BBHKPEMM_01646 3e-235 blpH 2.7.13.3 T protein histidine kinase activity
BBHKPEMM_01648 7.3e-237 mesE M Transport protein ComB
BBHKPEMM_01649 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BBHKPEMM_01650 0.0 mdlB V abc transporter atp-binding protein
BBHKPEMM_01651 0.0 mdlA V abc transporter atp-binding protein
BBHKPEMM_01653 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
BBHKPEMM_01654 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BBHKPEMM_01655 2.3e-72 yutD J protein conserved in bacteria
BBHKPEMM_01656 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
BBHKPEMM_01658 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
BBHKPEMM_01659 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBHKPEMM_01660 0.0 ftsI 3.4.16.4 M penicillin-binding protein
BBHKPEMM_01661 8.1e-46 ftsL D cell division protein FtsL
BBHKPEMM_01662 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BBHKPEMM_01663 3e-128
BBHKPEMM_01664 9.7e-32 yhaI J Protein of unknown function (DUF805)
BBHKPEMM_01665 1.3e-08 D nuclear chromosome segregation
BBHKPEMM_01666 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BBHKPEMM_01667 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BBHKPEMM_01668 2.2e-285 XK27_00765
BBHKPEMM_01669 8.1e-134 ecsA_2 V abc transporter atp-binding protein
BBHKPEMM_01670 5.2e-125 S Protein of unknown function (DUF554)
BBHKPEMM_01671 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
BBHKPEMM_01672 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BBHKPEMM_01673 9.8e-57 liaI S membrane
BBHKPEMM_01674 7e-10 XK27_02470 K LytTr DNA-binding domain protein
BBHKPEMM_01675 1.8e-65 KT response to antibiotic
BBHKPEMM_01676 5.2e-81 yebC M Membrane
BBHKPEMM_01677 2.9e-18 yebC M Membrane
BBHKPEMM_01678 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
BBHKPEMM_01679 1.8e-181 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
BBHKPEMM_01680 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBHKPEMM_01681 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBHKPEMM_01682 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
BBHKPEMM_01683 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBHKPEMM_01684 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBHKPEMM_01685 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BBHKPEMM_01687 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
BBHKPEMM_01688 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
BBHKPEMM_01689 0.0 scrA 2.7.1.211 G pts system
BBHKPEMM_01690 4.1e-291 scrB 3.2.1.26 GH32 G invertase
BBHKPEMM_01691 7.5e-180 scrR K Transcriptional
BBHKPEMM_01692 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBHKPEMM_01693 3.4e-62 yqhY S protein conserved in bacteria
BBHKPEMM_01694 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BBHKPEMM_01695 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
BBHKPEMM_01696 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
BBHKPEMM_01698 8e-44 V 'abc transporter, ATP-binding protein
BBHKPEMM_01699 1e-58 V 'abc transporter, ATP-binding protein
BBHKPEMM_01702 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBHKPEMM_01703 2e-169 corA P COG0598 Mg2 and Co2 transporters
BBHKPEMM_01704 3.1e-124 XK27_01040 S Pfam PF06570
BBHKPEMM_01706 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BBHKPEMM_01707 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BBHKPEMM_01708 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
BBHKPEMM_01709 2.8e-31 XK27_05745
BBHKPEMM_01710 2.5e-230 mutY L A G-specific adenine glycosylase
BBHKPEMM_01715 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBHKPEMM_01716 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BBHKPEMM_01717 1e-93 cvpA S toxin biosynthetic process
BBHKPEMM_01718 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BBHKPEMM_01719 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBHKPEMM_01720 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BBHKPEMM_01721 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BBHKPEMM_01722 2e-47 azlD E branched-chain amino acid
BBHKPEMM_01723 1.8e-114 azlC E AzlC protein
BBHKPEMM_01724 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBHKPEMM_01725 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
BBHKPEMM_01726 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
BBHKPEMM_01727 2.5e-33 ykzG S Belongs to the UPF0356 family
BBHKPEMM_01728 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBHKPEMM_01729 2.7e-40 pscB M CHAP domain protein
BBHKPEMM_01730 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
BBHKPEMM_01731 8.5e-63 glnR K Transcriptional regulator
BBHKPEMM_01732 1.3e-87 S Fusaric acid resistance protein-like
BBHKPEMM_01733 1.1e-12
BBHKPEMM_01734 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
BBHKPEMM_01735 3.2e-42 L Transposase
BBHKPEMM_01736 1.9e-46 L transposase activity
BBHKPEMM_01737 7.4e-23 L Transposase
BBHKPEMM_01738 1.8e-56 L transposition
BBHKPEMM_01739 9.1e-83 L Integrase core domain protein
BBHKPEMM_01740 2.9e-102 L Transposase
BBHKPEMM_01741 2.6e-112 L Transposase
BBHKPEMM_01742 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BBHKPEMM_01743 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBHKPEMM_01744 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
BBHKPEMM_01745 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BBHKPEMM_01746 1.1e-142 purR 2.4.2.7 F operon repressor
BBHKPEMM_01747 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
BBHKPEMM_01748 6.9e-173 rmuC S RmuC domain protein
BBHKPEMM_01749 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
BBHKPEMM_01750 8.6e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
BBHKPEMM_01751 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BBHKPEMM_01753 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
BBHKPEMM_01754 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BBHKPEMM_01755 1.6e-143 tatD L Hydrolase, tatd
BBHKPEMM_01756 7.2e-74 yccU S CoA-binding protein
BBHKPEMM_01757 4.8e-51 trxA O Belongs to the thioredoxin family
BBHKPEMM_01758 1.9e-141 S Macro domain protein
BBHKPEMM_01759 2e-09 L thioesterase
BBHKPEMM_01760 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
BBHKPEMM_01764 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
BBHKPEMM_01765 5e-84 L Transposase
BBHKPEMM_01766 1e-13 rpmH J Ribosomal protein L34
BBHKPEMM_01767 2e-186 jag S RNA-binding protein
BBHKPEMM_01768 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BBHKPEMM_01769 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
BBHKPEMM_01770 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
BBHKPEMM_01771 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
BBHKPEMM_01772 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBHKPEMM_01773 6.7e-81 amiA E transmembrane transport
BBHKPEMM_01774 4.2e-74 amiA E transmembrane transport
BBHKPEMM_01775 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
BBHKPEMM_01776 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BBHKPEMM_01777 3.5e-50 S Protein of unknown function (DUF3397)
BBHKPEMM_01778 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
BBHKPEMM_01779 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
BBHKPEMM_01780 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
BBHKPEMM_01781 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BBHKPEMM_01782 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
BBHKPEMM_01783 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
BBHKPEMM_01784 4.3e-77 XK27_09620 S reductase
BBHKPEMM_01785 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
BBHKPEMM_01786 1.2e-131 XK27_09615 S PAS domain
BBHKPEMM_01787 1.9e-07 fnt P Formate nitrite transporter
BBHKPEMM_01788 6.4e-54 fnt P Formate nitrite transporter
BBHKPEMM_01789 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
BBHKPEMM_01790 2.8e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
BBHKPEMM_01791 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
BBHKPEMM_01792 1.2e-165 L integrase core domain
BBHKPEMM_01793 1.1e-121 L Transposase
BBHKPEMM_01794 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
BBHKPEMM_01795 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBHKPEMM_01796 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
BBHKPEMM_01797 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
BBHKPEMM_01798 1.6e-21 S glycolate biosynthetic process
BBHKPEMM_01799 1.5e-64 S phosphatase activity
BBHKPEMM_01800 2e-157 rrmA 2.1.1.187 Q methyltransferase
BBHKPEMM_01803 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
BBHKPEMM_01804 1.9e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BBHKPEMM_01805 2.4e-36 yeeD O sulfur carrier activity
BBHKPEMM_01806 1.8e-187 yeeE S Sulphur transport
BBHKPEMM_01807 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BBHKPEMM_01808 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
BBHKPEMM_01809 4.1e-09 S Domain of unknown function (DUF4651)
BBHKPEMM_01810 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
BBHKPEMM_01811 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBHKPEMM_01812 1.8e-111 S CAAX amino terminal protease family protein
BBHKPEMM_01814 5e-67 V CAAX protease self-immunity
BBHKPEMM_01815 1.4e-33 V CAAX protease self-immunity
BBHKPEMM_01816 8.8e-27 lanR K sequence-specific DNA binding
BBHKPEMM_01817 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBHKPEMM_01818 7.7e-177 ytxK 2.1.1.72 L DNA methylase
BBHKPEMM_01819 6.8e-13 comGF U Putative Competence protein ComGF
BBHKPEMM_01820 4e-72 comGF U Competence protein ComGF
BBHKPEMM_01821 1.4e-15 NU Type II secretory pathway pseudopilin
BBHKPEMM_01822 1.8e-57 cglD NU Competence protein
BBHKPEMM_01823 8.5e-43 comGC U Required for transformation and DNA binding
BBHKPEMM_01824 9.2e-153 cglB NU type II secretion system
BBHKPEMM_01825 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBHKPEMM_01826 2.9e-68 S cog cog4699
BBHKPEMM_01827 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBHKPEMM_01828 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBHKPEMM_01829 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BBHKPEMM_01830 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BBHKPEMM_01831 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BBHKPEMM_01832 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
BBHKPEMM_01833 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
BBHKPEMM_01834 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
BBHKPEMM_01835 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
BBHKPEMM_01836 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
BBHKPEMM_01837 1.8e-57 asp S cog cog1302
BBHKPEMM_01838 3.2e-226 norN V Mate efflux family protein
BBHKPEMM_01839 1.9e-278 thrC 4.2.3.1 E Threonine synthase
BBHKPEMM_01840 1.9e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BBHKPEMM_01841 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
BBHKPEMM_01842 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BBHKPEMM_01843 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BBHKPEMM_01844 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
BBHKPEMM_01845 0.0 pepO 3.4.24.71 O Peptidase family M13
BBHKPEMM_01846 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
BBHKPEMM_01847 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
BBHKPEMM_01848 1.3e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
BBHKPEMM_01849 1.4e-54 treB 2.7.1.201 G PTS System
BBHKPEMM_01850 5.8e-21 treR K DNA-binding transcription factor activity
BBHKPEMM_01851 1.2e-85 treR K trehalose operon
BBHKPEMM_01852 3.3e-95 ywlG S Belongs to the UPF0340 family
BBHKPEMM_01855 2e-35 L PFAM Integrase, catalytic core
BBHKPEMM_01856 2e-94 L PFAM Integrase, catalytic core
BBHKPEMM_01857 3.3e-46 K Putative DNA-binding domain
BBHKPEMM_01858 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
BBHKPEMM_01859 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
BBHKPEMM_01860 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
BBHKPEMM_01865 1e-39
BBHKPEMM_01866 6.5e-31
BBHKPEMM_01867 5e-31 S Hypothetical protein (DUF2513)
BBHKPEMM_01868 7.7e-13
BBHKPEMM_01870 3.7e-216 S MvaI/BcnI restriction endonuclease family
BBHKPEMM_01872 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
BBHKPEMM_01873 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
BBHKPEMM_01875 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
BBHKPEMM_01876 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
BBHKPEMM_01877 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
BBHKPEMM_01878 3.3e-09 L PFAM Integrase, catalytic core
BBHKPEMM_01879 1.8e-111 L PFAM Integrase, catalytic core
BBHKPEMM_01880 3.3e-62 rplQ J ribosomal protein l17
BBHKPEMM_01881 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBHKPEMM_01882 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BBHKPEMM_01883 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBHKPEMM_01884 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
BBHKPEMM_01885 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBHKPEMM_01886 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
BBHKPEMM_01887 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BBHKPEMM_01888 4.4e-58 rplO J binds to the 23S rRNA
BBHKPEMM_01889 2.5e-23 rpmD J ribosomal protein l30
BBHKPEMM_01890 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BBHKPEMM_01891 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BBHKPEMM_01892 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BBHKPEMM_01893 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BBHKPEMM_01894 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BBHKPEMM_01895 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBHKPEMM_01896 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BBHKPEMM_01897 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BBHKPEMM_01898 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BBHKPEMM_01899 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
BBHKPEMM_01900 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BBHKPEMM_01901 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BBHKPEMM_01902 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BBHKPEMM_01903 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BBHKPEMM_01904 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBHKPEMM_01905 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
BBHKPEMM_01906 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
BBHKPEMM_01907 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BBHKPEMM_01908 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
BBHKPEMM_01909 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
BBHKPEMM_01910 0.0 XK27_09800 I Acyltransferase
BBHKPEMM_01911 1.7e-35 XK27_09805 S MORN repeat protein
BBHKPEMM_01912 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBHKPEMM_01913 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BBHKPEMM_01914 1.5e-89 adk 2.7.4.3 F topology modulation protein
BBHKPEMM_01915 8.6e-127 Z012_04635 K sequence-specific DNA binding
BBHKPEMM_01917 6.3e-16 C Radical SAM
BBHKPEMM_01918 3.4e-191 C Radical SAM
BBHKPEMM_01919 3.9e-287 V ABC transporter transmembrane region
BBHKPEMM_01920 2.5e-89 K sequence-specific DNA binding
BBHKPEMM_01921 1.3e-36 L Replication initiation factor
BBHKPEMM_01922 1.4e-107 L Replication initiation factor
BBHKPEMM_01923 1.9e-18 S Domain of unknown function (DUF3173)
BBHKPEMM_01924 3.5e-216 int L Belongs to the 'phage' integrase family
BBHKPEMM_01926 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
BBHKPEMM_01927 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
BBHKPEMM_01928 2.8e-44 yrzL S Belongs to the UPF0297 family
BBHKPEMM_01929 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BBHKPEMM_01930 4.2e-44 yrzB S Belongs to the UPF0473 family
BBHKPEMM_01931 6.6e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
BBHKPEMM_01932 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
BBHKPEMM_01933 7.5e-14
BBHKPEMM_01934 2.6e-91 XK27_10930 K acetyltransferase
BBHKPEMM_01935 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBHKPEMM_01936 2.3e-41 yaaA S Belongs to the UPF0246 family
BBHKPEMM_01937 1.2e-50 yaaA S Belongs to the UPF0246 family
BBHKPEMM_01938 9.9e-169 XK27_01785 S cog cog1284
BBHKPEMM_01939 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
BBHKPEMM_01941 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
BBHKPEMM_01942 5.7e-52 metE 2.1.1.14 E Methionine synthase
BBHKPEMM_01943 7.6e-64 metE 2.1.1.14 E Methionine synthase
BBHKPEMM_01944 9.2e-36 metE 2.1.1.14 E Methionine synthase
BBHKPEMM_01945 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
BBHKPEMM_01946 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BBHKPEMM_01948 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
BBHKPEMM_01949 2.7e-95 S Hydrophobic domain protein
BBHKPEMM_01951 3.7e-27 S Membrane
BBHKPEMM_01952 3.1e-101
BBHKPEMM_01953 1.8e-23 S Small integral membrane protein
BBHKPEMM_01954 1.1e-71 M Protein conserved in bacteria
BBHKPEMM_01955 4.9e-12 K CsbD-like
BBHKPEMM_01956 3.5e-97 nudL L hydrolase
BBHKPEMM_01957 3.4e-13 nudL L hydrolase
BBHKPEMM_01958 4e-19 K negative regulation of transcription, DNA-templated
BBHKPEMM_01959 1.7e-23 K negative regulation of transcription, DNA-templated
BBHKPEMM_01961 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
BBHKPEMM_01962 1.8e-88 S Putative adhesin
BBHKPEMM_01963 3.9e-161 XK27_06930 V domain protein
BBHKPEMM_01964 6.4e-96 XK27_06935 K transcriptional regulator
BBHKPEMM_01965 4.8e-55 ypaA M Membrane
BBHKPEMM_01966 2.7e-08
BBHKPEMM_01967 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BBHKPEMM_01968 8.2e-48 veg S Biofilm formation stimulator VEG
BBHKPEMM_01969 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
BBHKPEMM_01970 3.9e-70 rplI J binds to the 23S rRNA
BBHKPEMM_01971 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
BBHKPEMM_01972 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
BBHKPEMM_01973 1.5e-77 F NUDIX domain
BBHKPEMM_01974 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BBHKPEMM_01975 0.0 S Bacterial membrane protein, YfhO
BBHKPEMM_01976 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
BBHKPEMM_01977 5.3e-85 lytE M LysM domain protein
BBHKPEMM_01978 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBHKPEMM_01979 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBHKPEMM_01980 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBHKPEMM_01981 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBHKPEMM_01982 6.3e-138 ymfM S sequence-specific DNA binding
BBHKPEMM_01983 6.3e-232 ymfH S Peptidase M16
BBHKPEMM_01984 4.8e-235 ymfF S Peptidase M16
BBHKPEMM_01985 2.4e-44 yaaA S S4 domain protein YaaA
BBHKPEMM_01986 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BBHKPEMM_01987 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
BBHKPEMM_01988 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
BBHKPEMM_01989 4.2e-153 yvjA S membrane
BBHKPEMM_01990 6.7e-306 ybiT S abc transporter atp-binding protein
BBHKPEMM_01991 0.0 XK27_10405 S Bacterial membrane protein YfhO
BBHKPEMM_01995 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
BBHKPEMM_01996 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BBHKPEMM_01997 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
BBHKPEMM_01998 8.5e-134 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)