ORF_ID e_value Gene_name EC_number CAZy COGs Description
HHGCEAIN_00001 4.3e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHGCEAIN_00002 3e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHGCEAIN_00003 2.4e-33 yaaA S S4 domain
HHGCEAIN_00004 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHGCEAIN_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
HHGCEAIN_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHGCEAIN_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHGCEAIN_00008 2.2e-38 S COG NOG14552 non supervised orthologous group
HHGCEAIN_00011 1.5e-175 yaaC S YaaC-like Protein
HHGCEAIN_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HHGCEAIN_00013 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHGCEAIN_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HHGCEAIN_00015 4.7e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HHGCEAIN_00016 1.1e-202 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHGCEAIN_00017 2.3e-196 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HHGCEAIN_00018 1.3e-09
HHGCEAIN_00019 6.6e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HHGCEAIN_00020 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HHGCEAIN_00021 3.9e-208 yaaH M Glycoside Hydrolase Family
HHGCEAIN_00022 6.6e-96 yaaI Q COG1335 Amidases related to nicotinamidase
HHGCEAIN_00023 9.5e-83 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHGCEAIN_00024 2.3e-311 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHGCEAIN_00025 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHGCEAIN_00026 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHGCEAIN_00027 3.6e-32 yaaL S Protein of unknown function (DUF2508)
HHGCEAIN_00028 4.8e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HHGCEAIN_00029 2.2e-38 S COG NOG14552 non supervised orthologous group
HHGCEAIN_00032 7.9e-28 csfB S Inhibitor of sigma-G Gin
HHGCEAIN_00033 1.1e-99 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HHGCEAIN_00034 2.6e-176 yaaN P Belongs to the TelA family
HHGCEAIN_00035 1.9e-256 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HHGCEAIN_00036 7.8e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHGCEAIN_00037 7.5e-55 yaaQ S protein conserved in bacteria
HHGCEAIN_00038 3.8e-70 yaaR S protein conserved in bacteria
HHGCEAIN_00039 8.5e-179 holB 2.7.7.7 L DNA polymerase III
HHGCEAIN_00040 1.1e-144 yaaT S stage 0 sporulation protein
HHGCEAIN_00041 5e-36 yabA L Involved in initiation control of chromosome replication
HHGCEAIN_00042 1.6e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
HHGCEAIN_00043 5.2e-47 yazA L endonuclease containing a URI domain
HHGCEAIN_00044 2.8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHGCEAIN_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HHGCEAIN_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHGCEAIN_00047 2.2e-142 tatD L hydrolase, TatD
HHGCEAIN_00048 4e-216 rpfB GH23 T protein conserved in bacteria
HHGCEAIN_00049 2.3e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHGCEAIN_00050 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHGCEAIN_00051 8.2e-125 yabG S peptidase
HHGCEAIN_00052 7.8e-39 veg S protein conserved in bacteria
HHGCEAIN_00053 2.9e-27 sspF S DNA topological change
HHGCEAIN_00054 7.8e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HHGCEAIN_00055 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HHGCEAIN_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HHGCEAIN_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HHGCEAIN_00058 1.7e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHGCEAIN_00059 2.7e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHGCEAIN_00060 2.8e-103 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HHGCEAIN_00061 1.2e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHGCEAIN_00062 6.9e-39 yabK S Peptide ABC transporter permease
HHGCEAIN_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHGCEAIN_00064 2.6e-89 spoVT K stage V sporulation protein
HHGCEAIN_00065 5.8e-270 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHGCEAIN_00066 7e-270 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HHGCEAIN_00067 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HHGCEAIN_00068 1.9e-49 yabP S Sporulation protein YabP
HHGCEAIN_00069 2.5e-99 yabQ S spore cortex biosynthesis protein
HHGCEAIN_00070 9.2e-57 divIC D Septum formation initiator
HHGCEAIN_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HHGCEAIN_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HHGCEAIN_00075 1.2e-121 yabS S protein containing a von Willebrand factor type A (vWA) domain
HHGCEAIN_00076 9.2e-181 KLT serine threonine protein kinase
HHGCEAIN_00077 2.1e-263 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHGCEAIN_00078 2.5e-92 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HHGCEAIN_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHGCEAIN_00080 2.4e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HHGCEAIN_00081 1.2e-160 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHGCEAIN_00082 5.7e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HHGCEAIN_00083 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HHGCEAIN_00084 6.1e-263 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHGCEAIN_00085 5.7e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HHGCEAIN_00086 1.6e-149 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HHGCEAIN_00087 9.1e-153 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HHGCEAIN_00088 2.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHGCEAIN_00089 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HHGCEAIN_00090 7.1e-28 yazB K transcriptional
HHGCEAIN_00091 1.6e-180 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHGCEAIN_00092 1.6e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HHGCEAIN_00093 2.2e-38 S COG NOG14552 non supervised orthologous group
HHGCEAIN_00095 1.3e-07
HHGCEAIN_00098 2e-08
HHGCEAIN_00103 2.2e-38 S COG NOG14552 non supervised orthologous group
HHGCEAIN_00104 7.5e-77 ctsR K Belongs to the CtsR family
HHGCEAIN_00105 1.1e-60 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HHGCEAIN_00106 2.7e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HHGCEAIN_00107 0.0 clpC O Belongs to the ClpA ClpB family
HHGCEAIN_00108 3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHGCEAIN_00109 2.7e-194 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HHGCEAIN_00110 5.2e-185 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HHGCEAIN_00111 8.8e-122 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HHGCEAIN_00112 3.5e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HHGCEAIN_00113 1.6e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHGCEAIN_00114 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
HHGCEAIN_00115 1.1e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHGCEAIN_00116 1.7e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHGCEAIN_00117 1.8e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHGCEAIN_00118 1.8e-87 yacP S RNA-binding protein containing a PIN domain
HHGCEAIN_00119 4.4e-115 sigH K Belongs to the sigma-70 factor family
HHGCEAIN_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HHGCEAIN_00121 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
HHGCEAIN_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHGCEAIN_00123 2.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHGCEAIN_00124 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHGCEAIN_00125 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHGCEAIN_00126 4.8e-108 rsmC 2.1.1.172 J Methyltransferase
HHGCEAIN_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHGCEAIN_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHGCEAIN_00129 2.7e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HHGCEAIN_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHGCEAIN_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHGCEAIN_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHGCEAIN_00133 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHGCEAIN_00134 2.6e-172 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HHGCEAIN_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HHGCEAIN_00136 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHGCEAIN_00137 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
HHGCEAIN_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHGCEAIN_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHGCEAIN_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHGCEAIN_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHGCEAIN_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHGCEAIN_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHGCEAIN_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HHGCEAIN_00145 1.8e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHGCEAIN_00146 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHGCEAIN_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHGCEAIN_00148 3.9e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHGCEAIN_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHGCEAIN_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHGCEAIN_00151 1.3e-91 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHGCEAIN_00152 2.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHGCEAIN_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHGCEAIN_00154 1.9e-23 rpmD J Ribosomal protein L30
HHGCEAIN_00155 4.1e-72 rplO J binds to the 23S rRNA
HHGCEAIN_00156 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHGCEAIN_00157 2.8e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHGCEAIN_00158 2.6e-140 map 3.4.11.18 E Methionine aminopeptidase
HHGCEAIN_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHGCEAIN_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HHGCEAIN_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHGCEAIN_00162 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHGCEAIN_00163 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHGCEAIN_00164 4.7e-58 rplQ J Ribosomal protein L17
HHGCEAIN_00165 1.4e-153 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHGCEAIN_00166 1.2e-144 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHGCEAIN_00167 1.9e-136 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHGCEAIN_00168 5.9e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHGCEAIN_00169 7.1e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHGCEAIN_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HHGCEAIN_00171 2.7e-140 ybaJ Q Methyltransferase domain
HHGCEAIN_00172 5.3e-15 ybaJ Q Methyltransferase domain
HHGCEAIN_00173 3.6e-76 ybaK S Protein of unknown function (DUF2521)
HHGCEAIN_00174 2.4e-130 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HHGCEAIN_00175 2.5e-192 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HHGCEAIN_00176 1.7e-75 gerD
HHGCEAIN_00177 1.7e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HHGCEAIN_00178 1.2e-127 pdaB 3.5.1.104 G Polysaccharide deacetylase
HHGCEAIN_00179 2.2e-38 S COG NOG14552 non supervised orthologous group
HHGCEAIN_00182 1.6e-08
HHGCEAIN_00185 2.2e-38 S COG NOG14552 non supervised orthologous group
HHGCEAIN_00188 2.2e-38 S COG NOG14552 non supervised orthologous group
HHGCEAIN_00189 6.5e-213 glcP G Major Facilitator Superfamily
HHGCEAIN_00190 1e-245 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHGCEAIN_00191 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HHGCEAIN_00192 2.9e-201 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HHGCEAIN_00193 1.1e-222 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HHGCEAIN_00194 3.2e-170 ybaS 1.1.1.58 S Na -dependent transporter
HHGCEAIN_00195 2.2e-102 ybbA S Putative esterase
HHGCEAIN_00196 7e-176 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHGCEAIN_00197 1.5e-175 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHGCEAIN_00198 4.5e-169 feuA P Iron-uptake system-binding protein
HHGCEAIN_00199 1.3e-290 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HHGCEAIN_00200 7.8e-230 ybbC 3.2.1.52 S protein conserved in bacteria
HHGCEAIN_00201 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HHGCEAIN_00202 1.5e-236 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HHGCEAIN_00203 1.9e-229 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHGCEAIN_00204 8.3e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HHGCEAIN_00205 4.9e-59 ybbJ J acetyltransferase
HHGCEAIN_00206 3.4e-74 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HHGCEAIN_00210 1.5e-07
HHGCEAIN_00212 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HHGCEAIN_00213 2.6e-112 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HHGCEAIN_00214 1.1e-144 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHGCEAIN_00215 1.9e-216 ybbR S protein conserved in bacteria
HHGCEAIN_00216 2.3e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHGCEAIN_00217 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHGCEAIN_00218 9.2e-36
HHGCEAIN_00219 1.7e-197 O growth
HHGCEAIN_00220 1.1e-52 S ABC-2 family transporter protein
HHGCEAIN_00221 1.3e-98 ybdN
HHGCEAIN_00222 2.7e-131 ybdO S Domain of unknown function (DUF4885)
HHGCEAIN_00223 4.4e-160 dkgB S Aldo/keto reductase family
HHGCEAIN_00224 1.5e-92 yxaC M effector of murein hydrolase
HHGCEAIN_00225 2.2e-50 S LrgA family
HHGCEAIN_00226 2.3e-67 yxaD K helix_turn_helix multiple antibiotic resistance protein
HHGCEAIN_00227 2.7e-255 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HHGCEAIN_00228 3.6e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HHGCEAIN_00229 4.8e-178 T COG4585 Signal transduction histidine kinase
HHGCEAIN_00230 3e-100 KT LuxR family transcriptional regulator
HHGCEAIN_00231 6.4e-160 V COG1131 ABC-type multidrug transport system, ATPase component
HHGCEAIN_00232 8.4e-189 V COG0842 ABC-type multidrug transport system, permease component
HHGCEAIN_00233 1.8e-180 V ABC-2 family transporter protein
HHGCEAIN_00234 9.2e-23
HHGCEAIN_00235 1.4e-72 S Domain of unknown function (DUF4879)
HHGCEAIN_00236 1.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HHGCEAIN_00237 2.5e-100 yqeB
HHGCEAIN_00238 2.3e-38 ybyB
HHGCEAIN_00239 1.2e-275 ybeC E amino acid
HHGCEAIN_00240 1.2e-15 S Protein of unknown function (DUF2651)
HHGCEAIN_00241 2e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HHGCEAIN_00242 1.6e-257 glpT G -transporter
HHGCEAIN_00243 2.7e-17 S Protein of unknown function (DUF2651)
HHGCEAIN_00244 9.5e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HHGCEAIN_00246 3.9e-81 K Helix-turn-helix XRE-family like proteins
HHGCEAIN_00247 7e-187 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HHGCEAIN_00248 8.6e-207 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HHGCEAIN_00249 1.9e-92 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHGCEAIN_00250 5.1e-84 ybfM S SNARE associated Golgi protein
HHGCEAIN_00251 9e-150 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HHGCEAIN_00252 2.8e-39 ybfN
HHGCEAIN_00253 2.6e-188 yceA S Belongs to the UPF0176 family
HHGCEAIN_00254 6.3e-211 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHGCEAIN_00255 2.3e-193 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HHGCEAIN_00256 6.5e-238 mmuP E amino acid
HHGCEAIN_00257 7.7e-177 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HHGCEAIN_00258 1.9e-251 agcS E Sodium alanine symporter
HHGCEAIN_00259 8.3e-72 glsA 3.5.1.2 E Belongs to the glutaminase family
HHGCEAIN_00260 2.6e-34 glsA 3.5.1.2 E Belongs to the glutaminase family
HHGCEAIN_00261 4.6e-201 phoQ 2.7.13.3 T Histidine kinase
HHGCEAIN_00262 1.7e-155 glnL T Regulator
HHGCEAIN_00263 3.5e-126 ycbJ S Macrolide 2'-phosphotransferase
HHGCEAIN_00264 4.5e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HHGCEAIN_00265 1.3e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHGCEAIN_00266 3.5e-91 ydfN C nitroreductase
HHGCEAIN_00267 2.5e-180 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HHGCEAIN_00268 7.5e-62 mhqP S DoxX
HHGCEAIN_00269 3.5e-55 traF CO Thioredoxin
HHGCEAIN_00270 7.4e-62 ycbP S Protein of unknown function (DUF2512)
HHGCEAIN_00271 4.8e-78 sleB 3.5.1.28 M Cell wall
HHGCEAIN_00272 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HHGCEAIN_00273 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HHGCEAIN_00274 9e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHGCEAIN_00275 5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HHGCEAIN_00276 2.7e-189 ycbU E Selenocysteine lyase
HHGCEAIN_00277 1.4e-235 lmrB EGP the major facilitator superfamily
HHGCEAIN_00278 2.8e-61 yxaF K Transcriptional regulator
HHGCEAIN_00279 7.5e-46 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HHGCEAIN_00280 6.4e-16 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HHGCEAIN_00281 8e-191 yccF K DNA-templated transcriptional preinitiation complex assembly
HHGCEAIN_00282 1e-165 yccK C Aldo keto reductase
HHGCEAIN_00283 2.7e-164 ycdA S Domain of unknown function (DUF5105)
HHGCEAIN_00284 2.2e-236 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HHGCEAIN_00285 1e-251 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HHGCEAIN_00286 1.8e-87 cwlK M D-alanyl-D-alanine carboxypeptidase
HHGCEAIN_00287 2e-171 S response regulator aspartate phosphatase
HHGCEAIN_00288 2e-135 IQ Enoyl-(Acyl carrier protein) reductase
HHGCEAIN_00289 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HHGCEAIN_00290 1.6e-48 S Domain of unknown function (DUF4188)
HHGCEAIN_00291 1.5e-47 padR K Virulence activator alpha C-term
HHGCEAIN_00292 1.1e-162 adcA P Belongs to the bacterial solute-binding protein 9 family
HHGCEAIN_00293 1.6e-131 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HHGCEAIN_00294 2.2e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HHGCEAIN_00295 1.4e-181 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHGCEAIN_00296 6.2e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HHGCEAIN_00297 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
HHGCEAIN_00298 3.3e-106 yceE T proteins involved in stress response, homologs of TerZ and
HHGCEAIN_00299 1.7e-137 terC P Protein of unknown function (DUF475)
HHGCEAIN_00300 2.7e-307 yceG S Putative component of 'biosynthetic module'
HHGCEAIN_00301 7.4e-192 yceH P Belongs to the TelA family
HHGCEAIN_00302 1.8e-207 naiP P Uncharacterised MFS-type transporter YbfB
HHGCEAIN_00304 1.4e-226 proV 3.6.3.32 E glycine betaine
HHGCEAIN_00305 6.9e-137 opuAB P glycine betaine
HHGCEAIN_00306 4.2e-161 opuAC E glycine betaine
HHGCEAIN_00307 1e-204 amhX S amidohydrolase
HHGCEAIN_00308 7.4e-188 ycgA S Membrane
HHGCEAIN_00309 2e-26 ycgA S Membrane
HHGCEAIN_00310 4e-42 ycgB
HHGCEAIN_00311 2.3e-12 S RDD family
HHGCEAIN_00312 2.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHGCEAIN_00313 3.2e-257 mdr EGP Major facilitator Superfamily
HHGCEAIN_00314 2.9e-73 emrR K helix_turn_helix multiple antibiotic resistance protein
HHGCEAIN_00316 4.5e-42 ycgF E Lysine exporter protein LysE YggA
HHGCEAIN_00317 1.5e-58 ycgF E Lysine exporter protein LysE YggA
HHGCEAIN_00318 3.1e-144 yqcI S YqcI/YcgG family
HHGCEAIN_00319 4.5e-239 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HHGCEAIN_00320 4.2e-112 ycgI S Domain of unknown function (DUF1989)
HHGCEAIN_00321 3.2e-147 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHGCEAIN_00322 3.8e-129 4.2.1.118 G Xylose isomerase-like TIM barrel
HHGCEAIN_00323 2.7e-95 G COG0477 Permeases of the major facilitator superfamily
HHGCEAIN_00324 5.9e-113 G COG0477 Permeases of the major facilitator superfamily
HHGCEAIN_00325 3.3e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HHGCEAIN_00326 4e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HHGCEAIN_00327 7.6e-138 ycgL S Predicted nucleotidyltransferase
HHGCEAIN_00328 6.2e-168 ycgM E Proline dehydrogenase
HHGCEAIN_00329 2.9e-290 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HHGCEAIN_00330 3.2e-243 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHGCEAIN_00331 3.7e-224 ycgP QT COG2508 Regulator of polyketide synthase expression
HHGCEAIN_00332 2.4e-184 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HHGCEAIN_00333 9e-262 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HHGCEAIN_00334 1.5e-55 nirD 1.7.1.15 P Nitrite reductase
HHGCEAIN_00335 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HHGCEAIN_00336 2.7e-39 nasA P COG2223 Nitrate nitrite transporter
HHGCEAIN_00337 3.4e-222 yciC S GTPases (G3E family)
HHGCEAIN_00338 4.1e-217 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHGCEAIN_00339 5.2e-72 yckC S membrane
HHGCEAIN_00340 3.5e-49 S Protein of unknown function (DUF2680)
HHGCEAIN_00341 2.3e-286 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHGCEAIN_00342 4.3e-65 nin S Competence protein J (ComJ)
HHGCEAIN_00343 4.2e-77 nucA M Deoxyribonuclease NucA/NucB
HHGCEAIN_00344 1.3e-91 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HHGCEAIN_00345 1.2e-101 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HHGCEAIN_00346 1.1e-62 hxlR K transcriptional
HHGCEAIN_00347 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHGCEAIN_00348 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHGCEAIN_00349 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HHGCEAIN_00350 2.7e-137 srfAD Q thioesterase
HHGCEAIN_00351 1.5e-247 bamJ E Aminotransferase class I and II
HHGCEAIN_00352 5.5e-121 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HHGCEAIN_00353 8e-106 yczE S membrane
HHGCEAIN_00354 1.7e-131 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HHGCEAIN_00355 1e-117 tcyB P COG0765 ABC-type amino acid transport system, permease component
HHGCEAIN_00356 6.7e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HHGCEAIN_00357 1.6e-152 bsdA K LysR substrate binding domain
HHGCEAIN_00358 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HHGCEAIN_00359 4.2e-280 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HHGCEAIN_00360 3.6e-58 yclD
HHGCEAIN_00361 6.8e-265 dtpT E amino acid peptide transporter
HHGCEAIN_00362 7.8e-260 yclG M Pectate lyase superfamily protein
HHGCEAIN_00364 8.3e-280 gerKA EG Spore germination protein
HHGCEAIN_00365 1.6e-227 gerKC S spore germination
HHGCEAIN_00366 2.9e-191 gerKB F Spore germination protein
HHGCEAIN_00367 1.2e-247 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHGCEAIN_00368 2.2e-90 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHGCEAIN_00369 3.4e-138 yxeM M Belongs to the bacterial solute-binding protein 3 family
HHGCEAIN_00370 1.7e-114 yxeN P COG0765 ABC-type amino acid transport system, permease component
HHGCEAIN_00371 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HHGCEAIN_00372 1.6e-213 yxeP 3.5.1.47 E hydrolase activity
HHGCEAIN_00373 4.1e-240 yxeQ S MmgE/PrpD family
HHGCEAIN_00374 2.4e-119 yclH P ABC transporter
HHGCEAIN_00375 1.1e-222 yclI V ABC transporter (permease) YclI
HHGCEAIN_00376 9.9e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHGCEAIN_00377 9.5e-256 T PhoQ Sensor
HHGCEAIN_00378 2.7e-75 S aspartate phosphatase
HHGCEAIN_00381 1.7e-246 lysC 2.7.2.4 E Belongs to the aspartokinase family
HHGCEAIN_00382 6.3e-163 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHGCEAIN_00383 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHGCEAIN_00384 5.8e-135 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HHGCEAIN_00385 7.4e-172 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HHGCEAIN_00386 4e-246 ycnB EGP Major facilitator Superfamily
HHGCEAIN_00387 1.1e-148 ycnC K Transcriptional regulator
HHGCEAIN_00388 1.4e-133 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
HHGCEAIN_00389 1.4e-44 ycnE S Monooxygenase
HHGCEAIN_00390 1.8e-50 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HHGCEAIN_00391 2.7e-255 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHGCEAIN_00392 5.5e-210 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHGCEAIN_00393 1.3e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHGCEAIN_00394 2.6e-147 glcU U Glucose uptake
HHGCEAIN_00395 8.6e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHGCEAIN_00396 6.2e-95 ycnI S protein conserved in bacteria
HHGCEAIN_00397 3.5e-286 ycnJ P protein, homolog of Cu resistance protein CopC
HHGCEAIN_00398 8.4e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HHGCEAIN_00399 4.3e-53
HHGCEAIN_00400 2.1e-231 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HHGCEAIN_00401 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HHGCEAIN_00402 1.8e-201 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HHGCEAIN_00403 2.7e-59 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HHGCEAIN_00405 2.6e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HHGCEAIN_00406 7.9e-132 ycsF S Belongs to the UPF0271 (lamB) family
HHGCEAIN_00407 1.8e-207 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HHGCEAIN_00408 1.1e-141 ycsI S Belongs to the D-glutamate cyclase family
HHGCEAIN_00409 1.7e-131 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HHGCEAIN_00410 9.7e-178 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HHGCEAIN_00411 4.3e-125 kipR K Transcriptional regulator
HHGCEAIN_00412 1.2e-112 ycsK E anatomical structure formation involved in morphogenesis
HHGCEAIN_00414 1.1e-53 yczJ S biosynthesis
HHGCEAIN_00415 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HHGCEAIN_00416 6.8e-167 ydhF S Oxidoreductase
HHGCEAIN_00417 0.0 mtlR K transcriptional regulator, MtlR
HHGCEAIN_00418 7.4e-283 ydaB IQ acyl-CoA ligase
HHGCEAIN_00419 2.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHGCEAIN_00420 9.6e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HHGCEAIN_00421 3e-113 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HHGCEAIN_00422 3.4e-76 ydaG 1.4.3.5 S general stress protein
HHGCEAIN_00423 1.2e-135 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HHGCEAIN_00424 3.9e-47 ydzA EGP Major facilitator Superfamily
HHGCEAIN_00425 4.3e-74 lrpC K Transcriptional regulator
HHGCEAIN_00426 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHGCEAIN_00427 2.9e-188 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HHGCEAIN_00428 6.5e-143 ydaK T Diguanylate cyclase, GGDEF domain
HHGCEAIN_00429 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HHGCEAIN_00430 8.8e-229 ydaM M Glycosyl transferase family group 2
HHGCEAIN_00431 0.0 ydaN S Bacterial cellulose synthase subunit
HHGCEAIN_00432 0.0 ydaO E amino acid
HHGCEAIN_00433 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HHGCEAIN_00434 7.1e-61 K acetyltransferase
HHGCEAIN_00435 3e-79 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HHGCEAIN_00436 4e-58
HHGCEAIN_00437 2e-183 S Histidine kinase
HHGCEAIN_00440 4.7e-39
HHGCEAIN_00441 1.9e-223 mntH P H( )-stimulated, divalent metal cation uptake system
HHGCEAIN_00444 5.5e-33 ydaT
HHGCEAIN_00445 5.8e-73 yvaD S Family of unknown function (DUF5360)
HHGCEAIN_00446 7.2e-48 yvaE P Small Multidrug Resistance protein
HHGCEAIN_00447 1.2e-135 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HHGCEAIN_00449 7e-56 ydbB G Cupin domain
HHGCEAIN_00450 5.1e-57 ydbC S Domain of unknown function (DUF4937
HHGCEAIN_00451 2.3e-153 ydbD P Catalase
HHGCEAIN_00452 1.4e-41 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HHGCEAIN_00453 3.6e-135 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HHGCEAIN_00454 1.4e-292 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HHGCEAIN_00455 1.1e-113 dctR T COG4565 Response regulator of citrate malate metabolism
HHGCEAIN_00456 3.2e-223 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHGCEAIN_00457 2.2e-156 ydbI S AI-2E family transporter
HHGCEAIN_00458 5.7e-169 ydbJ V ABC transporter, ATP-binding protein
HHGCEAIN_00459 7.7e-127 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HHGCEAIN_00460 4.6e-52 ydbL
HHGCEAIN_00461 2.7e-200 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HHGCEAIN_00462 3.5e-12 S Fur-regulated basic protein B
HHGCEAIN_00463 9.2e-10 S Fur-regulated basic protein A
HHGCEAIN_00464 4.4e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHGCEAIN_00465 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HHGCEAIN_00466 1.3e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HHGCEAIN_00467 3.7e-249 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHGCEAIN_00468 1.8e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHGCEAIN_00469 4.6e-61 ydbS S Bacterial PH domain
HHGCEAIN_00470 6.6e-252 ydbT S Membrane
HHGCEAIN_00471 5.8e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HHGCEAIN_00472 4.1e-54 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHGCEAIN_00473 1.3e-179 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HHGCEAIN_00474 3.9e-215 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHGCEAIN_00475 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HHGCEAIN_00476 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HHGCEAIN_00477 3e-137 rsbR T Positive regulator of sigma-B
HHGCEAIN_00478 1.8e-57 rsbS T antagonist
HHGCEAIN_00479 4.2e-68 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HHGCEAIN_00480 1.8e-184 rsbU 3.1.3.3 KT phosphatase
HHGCEAIN_00481 4.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
HHGCEAIN_00482 6.6e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HHGCEAIN_00483 2e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHGCEAIN_00484 2.5e-104 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HHGCEAIN_00485 0.0 yhgF K COG2183 Transcriptional accessory protein
HHGCEAIN_00486 1.7e-14
HHGCEAIN_00487 4.6e-80 ydcK S Belongs to the SprT family
HHGCEAIN_00495 4.9e-54
HHGCEAIN_00496 8.2e-77 K Transcriptional regulator
HHGCEAIN_00497 2.3e-95 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HHGCEAIN_00498 5.1e-30 cspL K Cold shock
HHGCEAIN_00499 8.9e-111 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HHGCEAIN_00500 3.1e-101 S Protein of unknown function (DUF2812)
HHGCEAIN_00501 1.6e-49 K Transcriptional regulator PadR-like family
HHGCEAIN_00502 7.4e-237 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHGCEAIN_00503 5.9e-188 ydeG EGP Major facilitator superfamily
HHGCEAIN_00504 1.1e-50 S Patatin-like phospholipase
HHGCEAIN_00505 7e-45 S Patatin-like phospholipase
HHGCEAIN_00507 4.9e-254 ygaK C COG0277 FAD FMN-containing dehydrogenases
HHGCEAIN_00508 1.8e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHGCEAIN_00509 1.1e-151 czcD P COG1230 Co Zn Cd efflux system component
HHGCEAIN_00510 1.4e-160 S SNARE associated Golgi protein
HHGCEAIN_00511 5.8e-97 yrkC G Cupin domain
HHGCEAIN_00512 1.8e-82 yyaR K Acetyltransferase (GNAT) domain
HHGCEAIN_00513 6.6e-146 ydeE K AraC family transcriptional regulator
HHGCEAIN_00515 2.6e-186 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HHGCEAIN_00516 7.1e-47 ydeH
HHGCEAIN_00517 1.3e-160 S Sodium Bile acid symporter family
HHGCEAIN_00518 5.1e-198 adhA 1.1.1.1 C alcohol dehydrogenase
HHGCEAIN_00519 5e-61 yraB K helix_turn_helix, mercury resistance
HHGCEAIN_00520 1.4e-218 mleN_2 C antiporter
HHGCEAIN_00521 4.6e-247 K helix_turn_helix gluconate operon transcriptional repressor
HHGCEAIN_00522 2.6e-101 paiB K Transcriptional regulator
HHGCEAIN_00523 7.4e-169 ydeR EGP Major facilitator Superfamily
HHGCEAIN_00524 1.8e-99 ydeS K Transcriptional regulator
HHGCEAIN_00525 5.7e-150 ydeK EG -transporter
HHGCEAIN_00526 9e-251 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHGCEAIN_00527 2.6e-46 yraD M Spore coat protein
HHGCEAIN_00528 3.1e-24 yraE
HHGCEAIN_00529 6.3e-218 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHGCEAIN_00530 8.4e-63 yraF M Spore coat protein
HHGCEAIN_00531 8.4e-35 yraG
HHGCEAIN_00532 2.3e-35 ydfJ S drug exporters of the RND superfamily
HHGCEAIN_00533 1.2e-126 puuD S Peptidase C26
HHGCEAIN_00534 2.6e-289 expZ S ABC transporter
HHGCEAIN_00535 3.6e-91 ynaD J Acetyltransferase (GNAT) domain
HHGCEAIN_00536 1.5e-147 S Uncharacterized protein conserved in bacteria (DUF2179)
HHGCEAIN_00537 2.5e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HHGCEAIN_00538 2e-206 tcaB EGP Major facilitator Superfamily
HHGCEAIN_00539 1.8e-218 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHGCEAIN_00540 6.2e-154 K Helix-turn-helix XRE-family like proteins
HHGCEAIN_00541 1.1e-122 ydhB S membrane transporter protein
HHGCEAIN_00542 2e-77 bltD 2.3.1.57 K FR47-like protein
HHGCEAIN_00543 2.6e-141 bltR K helix_turn_helix, mercury resistance
HHGCEAIN_00544 3e-143 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HHGCEAIN_00545 9.3e-107 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HHGCEAIN_00546 7.5e-105 S Alpha/beta hydrolase family
HHGCEAIN_00547 5.7e-165 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HHGCEAIN_00548 1.3e-112 ydhC K FCD
HHGCEAIN_00549 1.2e-55 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HHGCEAIN_00550 1.4e-133 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HHGCEAIN_00552 2.5e-245 pbpE V Beta-lactamase
HHGCEAIN_00554 1.2e-97 ydhK M Protein of unknown function (DUF1541)
HHGCEAIN_00555 3.2e-193 pbuE EGP Major facilitator Superfamily
HHGCEAIN_00556 1.5e-129 ydhQ K UTRA
HHGCEAIN_00557 2.1e-112 K FCD
HHGCEAIN_00558 8.2e-208 yeaN P COG2807 Cyanate permease
HHGCEAIN_00559 1.1e-47 sugE P Small Multidrug Resistance protein
HHGCEAIN_00560 3.1e-48 ykkC P Small Multidrug Resistance protein
HHGCEAIN_00561 2e-98 yvdT K Transcriptional regulator
HHGCEAIN_00562 8.2e-293 yveA E amino acid
HHGCEAIN_00563 1.4e-161 ydhU P Catalase
HHGCEAIN_00564 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HHGCEAIN_00565 1.6e-177 yhfP 1.1.1.1 C Quinone oxidoreductase
HHGCEAIN_00566 4e-246 iolT EGP Major facilitator Superfamily
HHGCEAIN_00569 2.2e-38 S COG NOG14552 non supervised orthologous group
HHGCEAIN_00572 7.8e-08
HHGCEAIN_00574 4.9e-143 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HHGCEAIN_00575 3.2e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HHGCEAIN_00576 5.1e-122 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HHGCEAIN_00577 9e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HHGCEAIN_00578 8.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHGCEAIN_00579 3.4e-309 ydiF S ABC transporter
HHGCEAIN_00580 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HHGCEAIN_00581 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHGCEAIN_00582 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HHGCEAIN_00583 1.2e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHGCEAIN_00584 1.7e-27 ydiK S Domain of unknown function (DUF4305)
HHGCEAIN_00585 5.3e-125 ydiL S CAAX protease self-immunity
HHGCEAIN_00586 6.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHGCEAIN_00587 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHGCEAIN_00588 2.3e-77 S Phage integrase family
HHGCEAIN_00589 2.4e-30 yqaB E IrrE N-terminal-like domain
HHGCEAIN_00590 1.7e-25 S Protein of unknown function (DUF4064)
HHGCEAIN_00591 1.3e-48
HHGCEAIN_00592 7.9e-16 K Helix-turn-helix XRE-family like proteins
HHGCEAIN_00593 1.5e-12 K Helix-turn-helix XRE-family like proteins
HHGCEAIN_00594 3.8e-32
HHGCEAIN_00595 9.6e-61 S DNA binding
HHGCEAIN_00596 4.2e-85
HHGCEAIN_00598 1.2e-07 S Hypothetical protein Yqai
HHGCEAIN_00600 2.5e-78 yqaJ L YqaJ-like viral recombinase domain
HHGCEAIN_00601 3.5e-57 yqaJ L YqaJ-like viral recombinase domain
HHGCEAIN_00602 2.9e-127 recT L RecT family
HHGCEAIN_00603 1.4e-29 3.1.3.16 L DnaD domain protein
HHGCEAIN_00604 2.4e-120 xkdC L IstB-like ATP binding protein
HHGCEAIN_00606 2.3e-22 S YopX protein
HHGCEAIN_00607 6.8e-54 S Protein of unknown function (DUF1064)
HHGCEAIN_00609 5e-17 yqaO S Phage-like element PBSX protein XtrA
HHGCEAIN_00612 7.2e-168 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HHGCEAIN_00614 1.2e-42 S dUTPase
HHGCEAIN_00617 5.6e-07 S YopX protein
HHGCEAIN_00622 3.1e-48
HHGCEAIN_00624 5.3e-19 V VanZ like family
HHGCEAIN_00625 1.6e-67 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HHGCEAIN_00627 3.9e-12 K Transcriptional regulator
HHGCEAIN_00630 1.5e-71 yqaS L DNA packaging
HHGCEAIN_00631 6.4e-179 S Pfam:Terminase_3C
HHGCEAIN_00632 1.1e-126 S Phage portal protein, SPP1 Gp6-like
HHGCEAIN_00633 1.5e-92 S Phage Mu protein F like protein
HHGCEAIN_00635 5.4e-44 S Phage minor structural protein GP20
HHGCEAIN_00636 2.9e-54 gpG
HHGCEAIN_00639 3.5e-27 S Phage gp6-like head-tail connector protein
HHGCEAIN_00640 9.5e-29 S Phage head-tail joining protein
HHGCEAIN_00641 6.2e-38 S Bacteriophage HK97-gp10, putative tail-component
HHGCEAIN_00642 3.8e-29 S Protein of unknown function (DUF3168)
HHGCEAIN_00643 1.3e-34 S Phage tail tube protein
HHGCEAIN_00644 1.9e-25 S Phage tail assembly chaperone protein, TAC
HHGCEAIN_00645 9.3e-136
HHGCEAIN_00646 3.5e-47
HHGCEAIN_00647 1.6e-202 sidC L Phage minor structural protein
HHGCEAIN_00651 2.4e-30 xhlA S Haemolysin XhlA
HHGCEAIN_00652 4.8e-28 xhlB S SPP1 phage holin
HHGCEAIN_00653 6.1e-121 xlyB 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HHGCEAIN_00656 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
HHGCEAIN_00658 5.7e-62
HHGCEAIN_00659 0.0 K NB-ARC domain
HHGCEAIN_00660 1.7e-196 gutB 1.1.1.14 E Dehydrogenase
HHGCEAIN_00661 4.7e-244 gutA G MFS/sugar transport protein
HHGCEAIN_00662 3e-165 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HHGCEAIN_00663 2.1e-30 yjdJ S Domain of unknown function (DUF4306)
HHGCEAIN_00664 3.1e-111 pspA KT Phage shock protein A
HHGCEAIN_00665 1.7e-174 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHGCEAIN_00666 1.1e-114 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HHGCEAIN_00667 2e-143 ydjI S virion core protein (lumpy skin disease virus)
HHGCEAIN_00668 0.0 yrhL I Acyltransferase family
HHGCEAIN_00669 2.6e-139 rsiV S Protein of unknown function (DUF3298)
HHGCEAIN_00670 9.5e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HHGCEAIN_00671 6.4e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HHGCEAIN_00672 4.2e-62 ydjM M Lytic transglycolase
HHGCEAIN_00673 1.8e-131 ydjN U Involved in the tonB-independent uptake of proteins
HHGCEAIN_00675 3.2e-34 ydjO S Cold-inducible protein YdjO
HHGCEAIN_00676 9.5e-302 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HHGCEAIN_00677 3.9e-238 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HHGCEAIN_00678 2.2e-140 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHGCEAIN_00679 3e-176 yeaC S COG0714 MoxR-like ATPases
HHGCEAIN_00680 1.2e-198 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HHGCEAIN_00681 0.0 yebA E COG1305 Transglutaminase-like enzymes
HHGCEAIN_00682 1.8e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HHGCEAIN_00683 1.7e-88 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HHGCEAIN_00684 2.3e-249 S Domain of unknown function (DUF4179)
HHGCEAIN_00685 8.1e-209 pbuG S permease
HHGCEAIN_00686 2.4e-123 yebC M Membrane
HHGCEAIN_00688 1.5e-92 yebE S UPF0316 protein
HHGCEAIN_00689 9.5e-29 yebG S NETI protein
HHGCEAIN_00690 2.2e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHGCEAIN_00691 7.7e-219 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHGCEAIN_00692 5.2e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHGCEAIN_00693 3.6e-126 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HHGCEAIN_00694 4.2e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHGCEAIN_00695 1.2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHGCEAIN_00696 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHGCEAIN_00697 1.3e-268 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHGCEAIN_00698 8.7e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HHGCEAIN_00699 5.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHGCEAIN_00700 7.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HHGCEAIN_00701 4.7e-230 purD 6.3.4.13 F Belongs to the GARS family
HHGCEAIN_00702 3.8e-62 K helix_turn_helix ASNC type
HHGCEAIN_00703 4.2e-135 yjeH E Amino acid permease
HHGCEAIN_00704 5.4e-25 S Protein of unknown function (DUF2892)
HHGCEAIN_00705 0.0 yerA 3.5.4.2 F adenine deaminase
HHGCEAIN_00706 2.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
HHGCEAIN_00707 2.4e-50 yerC S protein conserved in bacteria
HHGCEAIN_00708 6.1e-296 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HHGCEAIN_00709 9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HHGCEAIN_00710 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HHGCEAIN_00711 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHGCEAIN_00712 5.2e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
HHGCEAIN_00713 5.4e-181 yerI S homoserine kinase type II (protein kinase fold)
HHGCEAIN_00714 3.1e-119 sapB S MgtC SapB transporter
HHGCEAIN_00715 4.9e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHGCEAIN_00716 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHGCEAIN_00717 2e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHGCEAIN_00718 2.6e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHGCEAIN_00719 1.1e-147 yerO K Transcriptional regulator
HHGCEAIN_00720 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHGCEAIN_00721 7.4e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HHGCEAIN_00722 1.6e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHGCEAIN_00723 1.9e-310 L Uncharacterized conserved protein (DUF2075)
HHGCEAIN_00724 8.5e-160 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HHGCEAIN_00725 1.4e-137 cylB V ABC-2 type transporter
HHGCEAIN_00726 2e-38 S Protein of unknown function, DUF600
HHGCEAIN_00727 1.5e-56 S Protein of unknown function, DUF600
HHGCEAIN_00728 1.9e-51 S Protein of unknown function, DUF600
HHGCEAIN_00729 7.8e-198 yobL L nucleic acid phosphodiester bond hydrolysis
HHGCEAIN_00730 1.3e-120 yobL L Belongs to the WXG100 family
HHGCEAIN_00731 2.7e-126 yeeN K transcriptional regulatory protein
HHGCEAIN_00733 1.7e-109 aadK G Streptomycin adenylyltransferase
HHGCEAIN_00734 9.1e-45 cotJA S Spore coat associated protein JA (CotJA)
HHGCEAIN_00735 1.3e-44 cotJB S CotJB protein
HHGCEAIN_00736 2e-103 cotJC P Spore Coat
HHGCEAIN_00737 2.2e-88 yesJ K Acetyltransferase (GNAT) family
HHGCEAIN_00739 3e-114 yetF S membrane
HHGCEAIN_00740 7e-53 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HHGCEAIN_00741 7e-62 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHGCEAIN_00742 3.7e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HHGCEAIN_00743 1.4e-20 yezD S Uncharacterized small protein (DUF2292)
HHGCEAIN_00744 2.4e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
HHGCEAIN_00745 2e-104 yetJ S Belongs to the BI1 family
HHGCEAIN_00746 4.9e-85 yetL K helix_turn_helix multiple antibiotic resistance protein
HHGCEAIN_00747 8.1e-194 yetM CH FAD binding domain
HHGCEAIN_00748 1.7e-196 yetN S Protein of unknown function (DUF3900)
HHGCEAIN_00749 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HHGCEAIN_00751 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HHGCEAIN_00752 4.3e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
HHGCEAIN_00753 9.2e-172 yfnG 4.2.1.45 M dehydratase
HHGCEAIN_00754 8.4e-173 yfnF M Nucleotide-diphospho-sugar transferase
HHGCEAIN_00755 4.3e-214 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HHGCEAIN_00756 4.5e-177 yfnD M Nucleotide-diphospho-sugar transferase
HHGCEAIN_00757 8.6e-213 fsr P COG0477 Permeases of the major facilitator superfamily
HHGCEAIN_00758 7.6e-242 yfnA E amino acid
HHGCEAIN_00759 3.2e-275 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHGCEAIN_00760 1.1e-105 yfmS NT chemotaxis protein
HHGCEAIN_00761 6.4e-165 IQ Enoyl-(Acyl carrier protein) reductase
HHGCEAIN_00762 6.5e-201 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HHGCEAIN_00763 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HHGCEAIN_00764 5.8e-68 yfmP K transcriptional
HHGCEAIN_00765 3.2e-196 yfmO EGP Major facilitator Superfamily
HHGCEAIN_00766 4.6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HHGCEAIN_00767 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HHGCEAIN_00768 3.7e-51 yfmJ S N-terminal domain of oxidoreductase
HHGCEAIN_00769 5.7e-79 yfmJ S N-terminal domain of oxidoreductase
HHGCEAIN_00770 4.1e-25 S Protein of unknown function (DUF3212)
HHGCEAIN_00771 1.3e-57 yflT S Heat induced stress protein YflT
HHGCEAIN_00772 2e-233 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HHGCEAIN_00773 1e-233 yflS P Sodium:sulfate symporter transmembrane region
HHGCEAIN_00774 4.3e-26 Q PFAM Collagen triple helix
HHGCEAIN_00779 1.2e-19 Q calcium- and calmodulin-responsive adenylate cyclase activity
HHGCEAIN_00780 1.1e-75 M1-820 Q Collagen triple helix repeat (20 copies)
HHGCEAIN_00781 0.0 ywpD T PhoQ Sensor
HHGCEAIN_00782 4.8e-151 M1-574 T Transcriptional regulatory protein, C terminal
HHGCEAIN_00783 0.0 M1-568 M cell wall anchor domain
HHGCEAIN_00784 4.6e-80 srtA 3.4.22.70 M Sortase family
HHGCEAIN_00785 1.1e-265 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HHGCEAIN_00786 6e-115 citT T response regulator
HHGCEAIN_00787 1.7e-171 yflP S Tripartite tricarboxylate transporter family receptor
HHGCEAIN_00788 7.4e-223 citM C Citrate transporter
HHGCEAIN_00789 5e-88 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HHGCEAIN_00790 1.9e-211 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HHGCEAIN_00791 1.3e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HHGCEAIN_00792 1.8e-116 yflK S protein conserved in bacteria
HHGCEAIN_00793 1.5e-14 yflJ S Protein of unknown function (DUF2639)
HHGCEAIN_00794 1.6e-18 yflI
HHGCEAIN_00795 9e-50 yflH S Protein of unknown function (DUF3243)
HHGCEAIN_00796 6.8e-136 map 3.4.11.18 E Methionine aminopeptidase
HHGCEAIN_00797 5.4e-240 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HHGCEAIN_00798 8.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
HHGCEAIN_00799 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HHGCEAIN_00800 4.7e-61 yhdN S Domain of unknown function (DUF1992)
HHGCEAIN_00801 4.5e-76 cotP O Belongs to the small heat shock protein (HSP20) family
HHGCEAIN_00802 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HHGCEAIN_00803 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
HHGCEAIN_00804 1.3e-35 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHGCEAIN_00805 1.1e-182 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHGCEAIN_00806 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HHGCEAIN_00807 6.1e-126 treR K transcriptional
HHGCEAIN_00808 4.6e-120 yfkO C nitroreductase
HHGCEAIN_00809 3.8e-118 yibF S YibE/F-like protein
HHGCEAIN_00810 6.8e-185 yibE S YibE/F-like protein
HHGCEAIN_00811 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HHGCEAIN_00812 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HHGCEAIN_00813 2.6e-178 K helix_turn _helix lactose operon repressor
HHGCEAIN_00814 3.2e-161 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HHGCEAIN_00815 4e-128 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HHGCEAIN_00816 8.4e-189 ydiM EGP Major facilitator Superfamily
HHGCEAIN_00817 3.9e-28 yfkK S Belongs to the UPF0435 family
HHGCEAIN_00818 2.2e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHGCEAIN_00819 4.4e-47 yfkI S gas vesicle protein
HHGCEAIN_00820 7.1e-142 yihY S Belongs to the UPF0761 family
HHGCEAIN_00821 1.1e-214 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HHGCEAIN_00822 1.5e-181 cax P COG0387 Ca2 H antiporter
HHGCEAIN_00823 1.1e-139 yfkD S YfkD-like protein
HHGCEAIN_00824 5.4e-142 yfkC M Mechanosensitive ion channel
HHGCEAIN_00825 7.5e-123 yfkA S YfkB-like domain
HHGCEAIN_00826 3.6e-91 yfkA S YfkB-like domain
HHGCEAIN_00827 4.9e-27 yfjT
HHGCEAIN_00828 4.9e-153 pdaA G deacetylase
HHGCEAIN_00829 3e-27 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HHGCEAIN_00830 1.2e-68 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HHGCEAIN_00831 1.8e-28
HHGCEAIN_00832 2.5e-183 corA P Mediates influx of magnesium ions
HHGCEAIN_00833 2.8e-157 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HHGCEAIN_00834 3.4e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHGCEAIN_00835 1.3e-79 O Subtilase family
HHGCEAIN_00836 4.1e-54 lmrA 3.6.3.44 V ABC transporter
HHGCEAIN_00837 2.1e-177 lmrA 3.6.3.44 V ABC transporter
HHGCEAIN_00838 0.0 KLT Protein kinase domain
HHGCEAIN_00846 4.7e-45 S YfzA-like protein
HHGCEAIN_00847 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHGCEAIN_00848 6e-79 yfjM S Psort location Cytoplasmic, score
HHGCEAIN_00849 2.5e-186 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHGCEAIN_00850 5.7e-186 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHGCEAIN_00851 6.8e-207 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHGCEAIN_00852 3.9e-238 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HHGCEAIN_00853 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HHGCEAIN_00854 3.2e-15 sspH S Belongs to the SspH family
HHGCEAIN_00855 1e-259 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHGCEAIN_00856 4.3e-138 glvR F Helix-turn-helix domain, rpiR family
HHGCEAIN_00857 5.4e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHGCEAIN_00858 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
HHGCEAIN_00859 1.9e-303 yfiB3 V ABC transporter
HHGCEAIN_00860 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HHGCEAIN_00861 9.2e-63 mhqP S DoxX
HHGCEAIN_00862 1.5e-155 yfiE 1.13.11.2 S glyoxalase
HHGCEAIN_00863 3.7e-77 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HHGCEAIN_00864 1.7e-70 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HHGCEAIN_00865 2e-92 padR K transcriptional
HHGCEAIN_00866 9.7e-101 1.6.5.2 S NADPH-dependent FMN reductase
HHGCEAIN_00867 8.5e-172 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HHGCEAIN_00868 2.2e-44 yrdF K ribonuclease inhibitor
HHGCEAIN_00869 6.1e-94 yfiT S Belongs to the metal hydrolase YfiT family
HHGCEAIN_00870 3.2e-284 yfiU EGP Major facilitator Superfamily
HHGCEAIN_00871 2.4e-78 yfiV K transcriptional
HHGCEAIN_00872 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHGCEAIN_00873 5.5e-153 yfhB 5.3.3.17 S PhzF family
HHGCEAIN_00874 5.9e-103 yfhC C nitroreductase
HHGCEAIN_00875 1e-24 yfhD S YfhD-like protein
HHGCEAIN_00877 2.1e-163 yfhF S nucleoside-diphosphate sugar epimerase
HHGCEAIN_00878 3.1e-139 recX 2.4.1.337 GT4 S Modulates RecA activity
HHGCEAIN_00879 4.7e-46 yfhH S Protein of unknown function (DUF1811)
HHGCEAIN_00880 5e-177 yfhI EGP Major facilitator Superfamily
HHGCEAIN_00882 9.4e-156 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HHGCEAIN_00883 8.3e-44 yfhJ S WVELL protein
HHGCEAIN_00884 1.2e-86 batE T Bacterial SH3 domain homologues
HHGCEAIN_00886 1.1e-12 yfhL S SdpI/YhfL protein family
HHGCEAIN_00887 2.2e-93 yfhM S Alpha/beta hydrolase family
HHGCEAIN_00888 1.1e-183 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HHGCEAIN_00889 0.0 yfhO S Bacterial membrane protein YfhO
HHGCEAIN_00890 5.9e-180 yfhP S membrane-bound metal-dependent
HHGCEAIN_00891 1.6e-136 L Belongs to the 'phage' integrase family
HHGCEAIN_00892 7.1e-43 E Zn peptidase
HHGCEAIN_00893 1.4e-31 K Helix-turn-helix XRE-family like proteins
HHGCEAIN_00894 6.5e-17
HHGCEAIN_00895 1.7e-28
HHGCEAIN_00897 1.7e-15 S Uncharacterized protein YqaH
HHGCEAIN_00898 4.3e-70 S Phage regulatory protein Rha (Phage_pRha)
HHGCEAIN_00899 1.4e-09
HHGCEAIN_00901 2e-82 L DnaD domain protein
HHGCEAIN_00902 8.8e-25 S Loader and inhibitor of phage G40P
HHGCEAIN_00903 4.4e-170 dnaB 3.6.4.12 L replicative DNA helicase
HHGCEAIN_00904 4.4e-24
HHGCEAIN_00909 5.8e-26 S Phage-like element PBSX protein XtrA
HHGCEAIN_00910 4e-79 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HHGCEAIN_00911 9.5e-47 S HicB_like antitoxin of bacterial toxin-antitoxin system
HHGCEAIN_00912 2.9e-19 N HicA toxin of bacterial toxin-antitoxin,
HHGCEAIN_00917 7.7e-33 L HNH endonuclease
HHGCEAIN_00918 9.4e-48 L Phage terminase, small subunit
HHGCEAIN_00919 1.6e-268 S Terminase
HHGCEAIN_00920 2.3e-77 S Phage portal protein
HHGCEAIN_00921 2.6e-68 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HHGCEAIN_00922 2.1e-118 S Phage capsid family
HHGCEAIN_00923 8.8e-21 L Phage gp6-like head-tail connector protein
HHGCEAIN_00924 5.3e-08 S Phage head-tail joining protein
HHGCEAIN_00925 8.4e-14 S Bacteriophage HK97-gp10, putative tail-component
HHGCEAIN_00927 5e-30 S Phage tail tube protein
HHGCEAIN_00929 4.3e-65 S Phage-related minor tail protein
HHGCEAIN_00930 1.9e-49 S Phage tail protein
HHGCEAIN_00931 9.7e-41 S Prophage endopeptidase tail
HHGCEAIN_00933 2.3e-102 E GDSL-like Lipase/Acylhydrolase family
HHGCEAIN_00934 1.4e-77 S Domain of unknown function (DUF2479)
HHGCEAIN_00937 4.6e-21 bhlA S BhlA holin family
HHGCEAIN_00938 6.5e-25 xhlB S SPP1 phage holin
HHGCEAIN_00939 1.4e-68 S N-acetylmuramoyl-L-alanine amidase activity
HHGCEAIN_00942 1.9e-72 S aspartate phosphatase
HHGCEAIN_00943 3.6e-16 S aspartate phosphatase
HHGCEAIN_00944 1.4e-203 mutY L A G-specific
HHGCEAIN_00945 1.8e-36 yfhS
HHGCEAIN_00946 2e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHGCEAIN_00948 1.5e-37 ygaB S YgaB-like protein
HHGCEAIN_00949 2.2e-104 ygaC J Belongs to the UPF0374 family
HHGCEAIN_00950 3.1e-301 ygaD V ABC transporter
HHGCEAIN_00951 5e-177 ygaE S Membrane
HHGCEAIN_00952 1.1e-242 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HHGCEAIN_00953 5e-84 bcp 1.11.1.15 O Peroxiredoxin
HHGCEAIN_00954 3.1e-80 perR P Belongs to the Fur family
HHGCEAIN_00955 2.1e-55 ygzB S UPF0295 protein
HHGCEAIN_00956 8.5e-162 ygxA S Nucleotidyltransferase-like
HHGCEAIN_00957 2.2e-38 S COG NOG14552 non supervised orthologous group
HHGCEAIN_00975 1e-99 L Belongs to the 'phage' integrase family
HHGCEAIN_00978 1.3e-38 S Helix-turn-helix domain
HHGCEAIN_00979 5.7e-39
HHGCEAIN_00984 1.2e-16
HHGCEAIN_00985 2.1e-63
HHGCEAIN_00988 5.6e-109 L DNA-dependent DNA replication
HHGCEAIN_00989 1.3e-08 yodN
HHGCEAIN_00990 7e-24
HHGCEAIN_00991 1.4e-142 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
HHGCEAIN_00992 2.5e-130 dnaG L Toprim-like
HHGCEAIN_00993 1.8e-07 S Cro/C1-type HTH DNA-binding domain
HHGCEAIN_00994 9.6e-44
HHGCEAIN_00999 1.2e-82
HHGCEAIN_01000 1.1e-48
HHGCEAIN_01001 1.4e-24
HHGCEAIN_01003 0.0 L 3'-5' exonuclease
HHGCEAIN_01005 1.7e-161
HHGCEAIN_01006 8.5e-24
HHGCEAIN_01007 6e-28 ruvC 3.1.22.4 L Crossover junction endodeoxyribonuclease RuvC
HHGCEAIN_01011 1.9e-41 nrdI 1.17.4.1 F Belongs to the NrdI family
HHGCEAIN_01012 2.4e-123 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHGCEAIN_01013 4.2e-24 L GIY-YIG catalytic domain
HHGCEAIN_01014 1.9e-182 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHGCEAIN_01016 4.4e-151 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHGCEAIN_01018 1.2e-68 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
HHGCEAIN_01021 2.3e-101 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HHGCEAIN_01022 2.5e-34 S protein conserved in bacteria
HHGCEAIN_01023 2.7e-64 S SprT-like family
HHGCEAIN_01024 9.9e-43
HHGCEAIN_01025 9.3e-61 2.7.1.24 H dephospho-CoA kinase activity
HHGCEAIN_01026 2.6e-169 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
HHGCEAIN_01028 3.6e-48 K Sigma-70, region 4
HHGCEAIN_01029 9.7e-51
HHGCEAIN_01030 1e-134
HHGCEAIN_01032 3.7e-119 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HHGCEAIN_01034 9.2e-23
HHGCEAIN_01035 5e-46
HHGCEAIN_01039 8.8e-10 K Cro/C1-type HTH DNA-binding domain
HHGCEAIN_01040 1.7e-78 2.1.1.294, 2.7.1.181 N bacterial-type flagellum assembly
HHGCEAIN_01041 4.8e-18
HHGCEAIN_01045 2.2e-67 L Phage integrase family
HHGCEAIN_01046 5.3e-256 S TIGRFAM Phage
HHGCEAIN_01047 3e-27 S Helix-turn-helix of insertion element transposase
HHGCEAIN_01048 5.2e-165
HHGCEAIN_01049 4.9e-79 S Phage minor capsid protein 2
HHGCEAIN_01050 1.8e-18
HHGCEAIN_01051 1.1e-147 S Family of unknown function (DUF5309)
HHGCEAIN_01054 1e-26
HHGCEAIN_01055 4.6e-17
HHGCEAIN_01056 7.9e-30
HHGCEAIN_01057 7.9e-49 eae N domain, Protein
HHGCEAIN_01058 3.6e-21
HHGCEAIN_01060 5.1e-41 D phage tail tape measure protein
HHGCEAIN_01061 3.2e-109 D phage tail tape measure protein
HHGCEAIN_01062 8e-61 S Phage tail protein
HHGCEAIN_01063 5.1e-76 L Prophage endopeptidase tail
HHGCEAIN_01064 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
HHGCEAIN_01065 2.3e-84
HHGCEAIN_01066 1.7e-12
HHGCEAIN_01068 4.5e-29 S BhlA holin family
HHGCEAIN_01069 3.4e-145 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
HHGCEAIN_01070 2.8e-33 S Bacteriophage A118-like holin, Hol118
HHGCEAIN_01072 4.2e-13 S YolD-like protein
HHGCEAIN_01073 3.1e-14 K Transcriptional regulator
HHGCEAIN_01074 4.6e-98 K Helix-turn-helix domain
HHGCEAIN_01076 4e-246 C Na+/H+ antiporter family
HHGCEAIN_01077 2.6e-121 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HHGCEAIN_01078 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HHGCEAIN_01079 1.3e-246 ygaK C Berberine and berberine like
HHGCEAIN_01081 6.4e-230 oppA5 E PFAM extracellular solute-binding protein family 5
HHGCEAIN_01082 3.5e-145 appB P Binding-protein-dependent transport system inner membrane component
HHGCEAIN_01083 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHGCEAIN_01084 9.8e-135 oppD3 P Belongs to the ABC transporter superfamily
HHGCEAIN_01085 2.9e-131 oppF3 E Belongs to the ABC transporter superfamily
HHGCEAIN_01086 4e-286 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HHGCEAIN_01087 4.7e-179 S Amidohydrolase
HHGCEAIN_01088 4.3e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HHGCEAIN_01089 2.5e-170 ssuA M Sulfonate ABC transporter
HHGCEAIN_01090 2.4e-142 ssuC P ABC transporter (permease)
HHGCEAIN_01091 8.2e-210 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HHGCEAIN_01093 3.9e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHGCEAIN_01094 8.9e-78 ygaO
HHGCEAIN_01095 1.8e-22 K Transcriptional regulator
HHGCEAIN_01097 4.2e-107 yhzB S B3/4 domain
HHGCEAIN_01098 6.2e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HHGCEAIN_01099 2.9e-168 yhbB S Putative amidase domain
HHGCEAIN_01100 2.2e-84 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHGCEAIN_01101 3.2e-102 yhbD K Protein of unknown function (DUF4004)
HHGCEAIN_01102 3.6e-54 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HHGCEAIN_01103 1.3e-56 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HHGCEAIN_01105 0.0 prkA T Ser protein kinase
HHGCEAIN_01106 1.8e-212 yhbH S Belongs to the UPF0229 family
HHGCEAIN_01107 1.6e-71 yhbI K DNA-binding transcription factor activity
HHGCEAIN_01108 4.4e-96 yhbJ V COG1566 Multidrug resistance efflux pump
HHGCEAIN_01109 4.1e-284 yhcA EGP Major facilitator Superfamily
HHGCEAIN_01110 1e-98 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
HHGCEAIN_01111 5.3e-49 yhcC
HHGCEAIN_01112 3.6e-52
HHGCEAIN_01113 1.7e-58 yhcF K Transcriptional regulator
HHGCEAIN_01114 2.8e-115 yhcG V ABC transporter, ATP-binding protein
HHGCEAIN_01115 1.9e-164 yhcH V ABC transporter, ATP-binding protein
HHGCEAIN_01116 7.9e-158 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HHGCEAIN_01117 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
HHGCEAIN_01118 4.5e-125 metQ M Belongs to the nlpA lipoprotein family
HHGCEAIN_01119 4e-182 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HHGCEAIN_01120 8.6e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHGCEAIN_01121 6.9e-40 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHGCEAIN_01122 4.4e-38 yhcM
HHGCEAIN_01123 6.3e-74 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHGCEAIN_01124 1.3e-154 yhcP
HHGCEAIN_01125 9.4e-113 yhcQ M Spore coat protein
HHGCEAIN_01126 3.8e-298 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
HHGCEAIN_01127 6.9e-99 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HHGCEAIN_01128 3.9e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHGCEAIN_01129 2.6e-62 yhcU S Family of unknown function (DUF5365)
HHGCEAIN_01130 8.4e-67 yhcV S COG0517 FOG CBS domain
HHGCEAIN_01131 1e-122 yhcW 5.4.2.6 S hydrolase
HHGCEAIN_01132 1.9e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HHGCEAIN_01133 5.8e-255 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHGCEAIN_01134 1e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HHGCEAIN_01135 1.7e-143 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HHGCEAIN_01136 8.9e-289 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHGCEAIN_01137 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HHGCEAIN_01138 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HHGCEAIN_01139 1.3e-194 yhcY 2.7.13.3 T Histidine kinase
HHGCEAIN_01140 2e-107 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHGCEAIN_01141 2.7e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
HHGCEAIN_01142 8e-38 yhdB S YhdB-like protein
HHGCEAIN_01143 1.3e-51 yhdC S Protein of unknown function (DUF3889)
HHGCEAIN_01144 2.3e-201 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HHGCEAIN_01145 2.6e-71 nsrR K Transcriptional regulator
HHGCEAIN_01146 3.5e-248 ygxB M Conserved TM helix
HHGCEAIN_01147 4.2e-264 ycgB S Stage V sporulation protein R
HHGCEAIN_01148 6.2e-252 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HHGCEAIN_01149 9.5e-123 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HHGCEAIN_01150 1.3e-157 citR K Transcriptional regulator
HHGCEAIN_01151 1.6e-197 citA 2.3.3.1 C Belongs to the citrate synthase family
HHGCEAIN_01152 3.1e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHGCEAIN_01153 6.1e-247 yhdG E amino acid
HHGCEAIN_01154 1.6e-196 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHGCEAIN_01155 8.1e-45 yhdK S Sigma-M inhibitor protein
HHGCEAIN_01156 3.2e-195 yhdL S Sigma factor regulator N-terminal
HHGCEAIN_01157 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HHGCEAIN_01158 5.8e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HHGCEAIN_01159 4e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HHGCEAIN_01160 1.8e-69 cueR K transcriptional
HHGCEAIN_01161 3.2e-217 yhdR 2.6.1.1 E Aminotransferase
HHGCEAIN_01162 3.3e-228 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHGCEAIN_01163 4.2e-248 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HHGCEAIN_01164 8.8e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHGCEAIN_01165 3.4e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHGCEAIN_01166 1.2e-121 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HHGCEAIN_01168 2.1e-197 yhdY M Mechanosensitive ion channel
HHGCEAIN_01169 3.1e-133 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HHGCEAIN_01170 1.4e-150 yheN G deacetylase
HHGCEAIN_01171 3.9e-148 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HHGCEAIN_01172 3.7e-97 pksA K Transcriptional regulator
HHGCEAIN_01173 4.1e-90 ymcC S Membrane
HHGCEAIN_01174 1.3e-82 T universal stress protein
HHGCEAIN_01175 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HHGCEAIN_01176 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HHGCEAIN_01177 3.2e-99 yheG GM NAD(P)H-binding
HHGCEAIN_01179 3.8e-28 sspB S spore protein
HHGCEAIN_01180 1.7e-36 yheE S Family of unknown function (DUF5342)
HHGCEAIN_01181 1.1e-248 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HHGCEAIN_01182 6.1e-202 yheC HJ YheC/D like ATP-grasp
HHGCEAIN_01183 8.5e-199 yheB S Belongs to the UPF0754 family
HHGCEAIN_01184 6.3e-52 yheA S Belongs to the UPF0342 family
HHGCEAIN_01185 2.7e-152 yhaX S haloacid dehalogenase-like hydrolase
HHGCEAIN_01186 1.1e-291 hemZ H coproporphyrinogen III oxidase
HHGCEAIN_01187 1.1e-245 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
HHGCEAIN_01188 2.5e-204 yhaU P COG0475 Kef-type K transport systems, membrane components
HHGCEAIN_01189 1.9e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HHGCEAIN_01191 4.2e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HHGCEAIN_01192 1.2e-14 S YhzD-like protein
HHGCEAIN_01193 5.9e-163 yhaQ S ABC transporter, ATP-binding protein
HHGCEAIN_01194 1.7e-203 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HHGCEAIN_01195 3.5e-230 yhaO L DNA repair exonuclease
HHGCEAIN_01196 0.0 yhaN L AAA domain
HHGCEAIN_01197 1.1e-175 yhaM L Shows a 3'-5' exoribonuclease activity
HHGCEAIN_01198 2.3e-31 yhaL S Sporulation protein YhaL
HHGCEAIN_01199 3.2e-113 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HHGCEAIN_01200 1e-93 yhaK S Putative zincin peptidase
HHGCEAIN_01201 9.9e-55 yhaI S Protein of unknown function (DUF1878)
HHGCEAIN_01202 1.5e-109 hpr K Negative regulator of protease production and sporulation
HHGCEAIN_01203 9e-38 yhaH S YtxH-like protein
HHGCEAIN_01204 2e-17
HHGCEAIN_01205 1.3e-74 trpP S Tryptophan transporter TrpP
HHGCEAIN_01206 1.5e-197 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HHGCEAIN_01207 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HHGCEAIN_01208 4.4e-135 ecsA V transporter (ATP-binding protein)
HHGCEAIN_01209 5.7e-217 ecsB U ABC transporter
HHGCEAIN_01210 1.1e-116 ecsC S EcsC protein family
HHGCEAIN_01211 1.4e-215 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HHGCEAIN_01212 2.5e-237 yhfA C membrane
HHGCEAIN_01213 6e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HHGCEAIN_01214 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHGCEAIN_01215 1.9e-198 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HHGCEAIN_01216 1.7e-176 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HHGCEAIN_01217 6.6e-273 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HHGCEAIN_01218 3.5e-100 yhgD K Transcriptional regulator
HHGCEAIN_01219 1.6e-255 yhgE S YhgE Pip N-terminal domain protein
HHGCEAIN_01220 1.3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHGCEAIN_01222 1.5e-194 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HHGCEAIN_01223 1.2e-225 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHGCEAIN_01224 6.2e-134 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HHGCEAIN_01225 1.7e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
HHGCEAIN_01226 5.7e-107 yhfK GM NmrA-like family
HHGCEAIN_01227 1.7e-295 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HHGCEAIN_01228 8.1e-64 yhfM
HHGCEAIN_01229 5.4e-231 yhfN 3.4.24.84 O Peptidase M48
HHGCEAIN_01230 1.6e-200 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HHGCEAIN_01231 7e-129 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HHGCEAIN_01232 2.7e-100 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HHGCEAIN_01233 1.4e-193 vraB 2.3.1.9 I Belongs to the thiolase family
HHGCEAIN_01234 1.8e-238 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HHGCEAIN_01235 3.1e-85 bioY S BioY family
HHGCEAIN_01236 1.1e-116 hemAT NT chemotaxis protein
HHGCEAIN_01237 6.2e-54 hemAT NT chemotaxis protein
HHGCEAIN_01238 1e-262 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HHGCEAIN_01239 1.4e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHGCEAIN_01240 1.2e-30 yhzC S IDEAL
HHGCEAIN_01241 4.2e-109 comK K Competence transcription factor
HHGCEAIN_01242 4.1e-57 frataxin S Domain of unknown function (DU1801)
HHGCEAIN_01243 6.1e-171 els S Acetyltransferase, GNAT family
HHGCEAIN_01244 3.4e-121 yrpD S Domain of unknown function, YrpD
HHGCEAIN_01245 7.8e-42 yhjA S Excalibur calcium-binding domain
HHGCEAIN_01246 3.3e-47 S Belongs to the UPF0145 family
HHGCEAIN_01247 1.2e-261 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHGCEAIN_01248 3.1e-27 yhjC S Protein of unknown function (DUF3311)
HHGCEAIN_01249 7.9e-58 yhjD
HHGCEAIN_01250 1e-105 yhjE S SNARE associated Golgi protein
HHGCEAIN_01251 6.6e-90 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HHGCEAIN_01252 3.4e-264 yhjG CH FAD binding domain
HHGCEAIN_01253 6.1e-91 yhjH K helix_turn_helix multiple antibiotic resistance protein
HHGCEAIN_01254 7.9e-184 abrB S membrane
HHGCEAIN_01255 2.6e-198 blt EGP Major facilitator Superfamily
HHGCEAIN_01256 3.5e-106 K QacR-like protein, C-terminal region
HHGCEAIN_01257 1.4e-82 yhjR S Rubrerythrin
HHGCEAIN_01258 1.2e-118 ydfS S Protein of unknown function (DUF421)
HHGCEAIN_01259 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HHGCEAIN_01260 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HHGCEAIN_01261 9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HHGCEAIN_01262 0.0 sbcC L COG0419 ATPase involved in DNA repair
HHGCEAIN_01263 3.9e-50 yisB V COG1403 Restriction endonuclease
HHGCEAIN_01264 1.7e-31 gerPF S Spore germination protein gerPA/gerPF
HHGCEAIN_01265 1e-58 gerPE S Spore germination protein GerPE
HHGCEAIN_01266 7.7e-22 gerPD S Spore germination protein
HHGCEAIN_01267 5.9e-61 gerPC S Spore germination protein
HHGCEAIN_01268 1.4e-31 gerPB S cell differentiation
HHGCEAIN_01269 8.4e-34 gerPA S Spore germination protein
HHGCEAIN_01270 1.6e-08 yisI S Spo0E like sporulation regulatory protein
HHGCEAIN_01271 2e-166 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HHGCEAIN_01272 1.9e-59 yisL S UPF0344 protein
HHGCEAIN_01273 0.0 wprA O Belongs to the peptidase S8 family
HHGCEAIN_01274 3.1e-90 yisN S Protein of unknown function (DUF2777)
HHGCEAIN_01275 0.0 asnO 6.3.5.4 E Asparagine synthase
HHGCEAIN_01276 7e-117 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HHGCEAIN_01277 1e-241 yisQ V Mate efflux family protein
HHGCEAIN_01278 8e-157 yisR K Transcriptional regulator
HHGCEAIN_01279 8.6e-142 purR K helix_turn _helix lactose operon repressor
HHGCEAIN_01280 4.4e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HHGCEAIN_01281 5.2e-77 yisT S DinB family
HHGCEAIN_01282 1e-73 argO S Lysine exporter protein LysE YggA
HHGCEAIN_01283 1.5e-187 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHGCEAIN_01284 2.4e-49 mcbG S Pentapeptide repeats (9 copies)
HHGCEAIN_01285 6e-76 yjcF S Acetyltransferase (GNAT) domain
HHGCEAIN_01286 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HHGCEAIN_01287 1.9e-54 yajQ S Belongs to the UPF0234 family
HHGCEAIN_01288 3.9e-156 cvfB S protein conserved in bacteria
HHGCEAIN_01289 5e-147 yufN S ABC transporter substrate-binding protein PnrA-like
HHGCEAIN_01290 1.9e-175 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HHGCEAIN_01291 1.8e-229 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HHGCEAIN_01292 8.2e-154 yitS S protein conserved in bacteria
HHGCEAIN_01293 8.7e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HHGCEAIN_01294 1.2e-79 ipi S Intracellular proteinase inhibitor
HHGCEAIN_01295 9.8e-26 S Protein of unknown function (DUF3813)
HHGCEAIN_01296 2e-07
HHGCEAIN_01297 4.4e-149 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HHGCEAIN_01298 3.2e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HHGCEAIN_01299 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HHGCEAIN_01300 3.6e-70 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HHGCEAIN_01301 5.1e-265 yitY C D-arabinono-1,4-lactone oxidase
HHGCEAIN_01302 9.4e-87 norB G Major Facilitator Superfamily
HHGCEAIN_01303 1.9e-192 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HHGCEAIN_01304 3.2e-220 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HHGCEAIN_01305 9.8e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HHGCEAIN_01306 2.2e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HHGCEAIN_01307 1.4e-195 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HHGCEAIN_01308 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HHGCEAIN_01309 3.4e-172 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHGCEAIN_01310 2.1e-27 yjzC S YjzC-like protein
HHGCEAIN_01311 6.3e-22 yjzD S Protein of unknown function (DUF2929)
HHGCEAIN_01312 4.4e-132 yjaU I carboxylic ester hydrolase activity
HHGCEAIN_01313 5.5e-98 yjaV
HHGCEAIN_01314 2e-163 med S Transcriptional activator protein med
HHGCEAIN_01315 3.3e-26 comZ S ComZ
HHGCEAIN_01317 1.6e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHGCEAIN_01318 1.2e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHGCEAIN_01319 2.1e-140 yjaZ O Zn-dependent protease
HHGCEAIN_01320 1.9e-178 appD P Belongs to the ABC transporter superfamily
HHGCEAIN_01321 1.7e-182 appF E Belongs to the ABC transporter superfamily
HHGCEAIN_01322 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HHGCEAIN_01323 4.8e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHGCEAIN_01324 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHGCEAIN_01325 5.5e-146 yjbA S Belongs to the UPF0736 family
HHGCEAIN_01326 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HHGCEAIN_01327 0.0 oppA E ABC transporter substrate-binding protein
HHGCEAIN_01328 7.8e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHGCEAIN_01329 6.5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHGCEAIN_01330 1.2e-199 oppD P Belongs to the ABC transporter superfamily
HHGCEAIN_01331 4.4e-169 oppF E Belongs to the ABC transporter superfamily
HHGCEAIN_01332 9.2e-220 S Putative glycosyl hydrolase domain
HHGCEAIN_01333 2.9e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHGCEAIN_01334 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHGCEAIN_01335 1.1e-108 yjbE P Integral membrane protein TerC family
HHGCEAIN_01336 5e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HHGCEAIN_01337 1.9e-201 yjbF S Competence protein
HHGCEAIN_01338 0.0 pepF E oligoendopeptidase F
HHGCEAIN_01339 5.8e-19
HHGCEAIN_01340 2.6e-166 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HHGCEAIN_01341 5.9e-70 yjbI S Bacterial-like globin
HHGCEAIN_01342 7.9e-107 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HHGCEAIN_01343 7.1e-93 yjbK S protein conserved in bacteria
HHGCEAIN_01344 5e-60 yjbL S Belongs to the UPF0738 family
HHGCEAIN_01345 1.9e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
HHGCEAIN_01346 3.9e-150 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHGCEAIN_01347 4.1e-156 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHGCEAIN_01348 3.8e-139 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HHGCEAIN_01349 3.3e-88 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HHGCEAIN_01350 8.7e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HHGCEAIN_01351 4e-102 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HHGCEAIN_01352 1.8e-201 thiO 1.4.3.19 E Glycine oxidase
HHGCEAIN_01353 7.5e-29 thiS H Thiamine biosynthesis
HHGCEAIN_01354 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HHGCEAIN_01355 3e-179 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HHGCEAIN_01356 2.6e-141 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HHGCEAIN_01357 6.8e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HHGCEAIN_01358 5.4e-72 yjbX S Spore coat protein
HHGCEAIN_01359 1.8e-80 cotZ S Spore coat protein
HHGCEAIN_01360 1.3e-92 cotY S Spore coat protein Z
HHGCEAIN_01361 1.3e-69 cotX S Spore Coat Protein X and V domain
HHGCEAIN_01362 1.4e-21 cotW
HHGCEAIN_01363 8.6e-34 cotV S Spore Coat Protein X and V domain
HHGCEAIN_01364 2.8e-55 yjcA S Protein of unknown function (DUF1360)
HHGCEAIN_01368 8.4e-38 spoVIF S Stage VI sporulation protein F
HHGCEAIN_01369 0.0 yjcD 3.6.4.12 L DNA helicase
HHGCEAIN_01370 6.2e-33
HHGCEAIN_01371 2.4e-125 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HHGCEAIN_01372 1.7e-120 S ABC-2 type transporter
HHGCEAIN_01373 2.1e-129 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
HHGCEAIN_01374 8.8e-34 K SpoVT / AbrB like domain
HHGCEAIN_01375 2e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHGCEAIN_01376 7.8e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HHGCEAIN_01377 1.2e-121 yjcH P COG2382 Enterochelin esterase and related enzymes
HHGCEAIN_01378 9e-209 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HHGCEAIN_01379 1.7e-213 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HHGCEAIN_01381 5.9e-55
HHGCEAIN_01382 2.6e-74 yobL S Bacterial EndoU nuclease
HHGCEAIN_01383 4.5e-31
HHGCEAIN_01384 2.1e-89 yokH G SMI1 / KNR4 family
HHGCEAIN_01385 5.5e-103 1.1.1.169 H 2-dehydropantoate 2-reductase
HHGCEAIN_01386 4.3e-22 yokK S SMI1 / KNR4 family
HHGCEAIN_01387 3e-62 H Acetyltransferase (GNAT) domain
HHGCEAIN_01388 3.7e-25
HHGCEAIN_01389 1.1e-197 K Psort location Cytoplasmic, score
HHGCEAIN_01390 1.5e-101 K Psort location Cytoplasmic, score
HHGCEAIN_01391 7.7e-189 K Psort location Cytoplasmic, score
HHGCEAIN_01392 3.5e-36 S YolD-like protein
HHGCEAIN_01393 5.8e-46 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHGCEAIN_01394 2.2e-28 S Bacillus cereus group antimicrobial protein
HHGCEAIN_01399 1.5e-16 N Kelch motif
HHGCEAIN_01401 2e-153 bla 3.5.2.6 V beta-lactamase
HHGCEAIN_01402 3e-44 yjcS S Antibiotic biosynthesis monooxygenase
HHGCEAIN_01403 3e-238 yfjF EGP Belongs to the major facilitator superfamily
HHGCEAIN_01404 2.2e-76 napB K helix_turn_helix multiple antibiotic resistance protein
HHGCEAIN_01405 1.8e-217 ganA 3.2.1.89 G arabinogalactan
HHGCEAIN_01406 5.4e-298 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHGCEAIN_01407 3.4e-49 lacF 2.7.1.207 G phosphotransferase system
HHGCEAIN_01408 1.6e-279 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HHGCEAIN_01409 3.7e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
HHGCEAIN_01410 5.8e-118 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HHGCEAIN_01411 7.6e-34
HHGCEAIN_01412 4.5e-52 K helix_turn_helix multiple antibiotic resistance protein
HHGCEAIN_01413 2.2e-103 yhiD S MgtC SapB transporter
HHGCEAIN_01415 5.4e-20 yjfB S Putative motility protein
HHGCEAIN_01416 5.9e-62 T PhoQ Sensor
HHGCEAIN_01417 2.9e-94 yjgB S Domain of unknown function (DUF4309)
HHGCEAIN_01418 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HHGCEAIN_01419 3.8e-118 ybbM S transport system, permease component
HHGCEAIN_01420 4.7e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HHGCEAIN_01421 6.8e-29
HHGCEAIN_01422 1.8e-215 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HHGCEAIN_01423 2e-214 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HHGCEAIN_01424 9.2e-69 yjgD S Protein of unknown function (DUF1641)
HHGCEAIN_01425 6.2e-83 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HHGCEAIN_01426 4.8e-57 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HHGCEAIN_01427 6.5e-33 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
HHGCEAIN_01428 5.9e-172 yjlA EG Putative multidrug resistance efflux transporter
HHGCEAIN_01429 7.3e-86 yjlB S Cupin domain
HHGCEAIN_01430 7e-66 yjlC S Protein of unknown function (DUF1641)
HHGCEAIN_01431 3.2e-217 yjlD 1.6.99.3 C NADH dehydrogenase
HHGCEAIN_01432 2e-65 uxaC 5.3.1.12 G glucuronate isomerase
HHGCEAIN_01433 1.6e-180 exuR K transcriptional
HHGCEAIN_01434 9.7e-161 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HHGCEAIN_01435 5.2e-87 T Transcriptional regulatory protein, C terminal
HHGCEAIN_01436 1.4e-128 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HHGCEAIN_01438 6.9e-128 MA20_18170 S membrane transporter protein
HHGCEAIN_01439 4.9e-76 yjoA S DinB family
HHGCEAIN_01440 3.2e-214 S response regulator aspartate phosphatase
HHGCEAIN_01442 3.1e-162 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HHGCEAIN_01443 6.8e-60 yjqA S Bacterial PH domain
HHGCEAIN_01444 4.8e-100 yjqB S phage-related replication protein
HHGCEAIN_01445 1.5e-106 xkdA E IrrE N-terminal-like domain
HHGCEAIN_01446 2.6e-55 xre K Helix-turn-helix XRE-family like proteins
HHGCEAIN_01448 3.2e-144 xkdC L Bacterial dnaA protein
HHGCEAIN_01451 4.5e-10 yqaO S Phage-like element PBSX protein XtrA
HHGCEAIN_01452 8.5e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HHGCEAIN_01453 1.5e-109 xtmA L phage terminase small subunit
HHGCEAIN_01454 1.6e-209 xtmB S phage terminase, large subunit
HHGCEAIN_01455 2.5e-240 yqbA S portal protein
HHGCEAIN_01456 7.5e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
HHGCEAIN_01457 3e-157 xkdG S Phage capsid family
HHGCEAIN_01458 3.3e-40 yqbH S Domain of unknown function (DUF3599)
HHGCEAIN_01459 4.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
HHGCEAIN_01460 5.8e-58 xkdJ
HHGCEAIN_01461 6.3e-15
HHGCEAIN_01462 3.2e-224 xkdK S Phage tail sheath C-terminal domain
HHGCEAIN_01463 2e-74 xkdM S Phage tail tube protein
HHGCEAIN_01464 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
HHGCEAIN_01465 3.4e-19
HHGCEAIN_01466 5.9e-73 xkdO L Transglycosylase SLT domain
HHGCEAIN_01467 6.7e-180 xkdO L Transglycosylase SLT domain
HHGCEAIN_01468 1.3e-111 xkdP S Lysin motif
HHGCEAIN_01469 2.9e-163 xkdQ 3.2.1.96 G NLP P60 protein
HHGCEAIN_01470 8.5e-33 xkdR S Protein of unknown function (DUF2577)
HHGCEAIN_01471 2.7e-57 xkdS S Protein of unknown function (DUF2634)
HHGCEAIN_01472 1.5e-162 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HHGCEAIN_01473 4.2e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HHGCEAIN_01474 6.1e-26
HHGCEAIN_01475 2.1e-160
HHGCEAIN_01477 6.8e-27 xkdX
HHGCEAIN_01478 2.5e-130 xepA
HHGCEAIN_01479 7.4e-37 xhlA S Haemolysin XhlA
HHGCEAIN_01480 4.3e-37 xhlB S SPP1 phage holin
HHGCEAIN_01481 6.4e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HHGCEAIN_01482 8.7e-23 spoIISB S Stage II sporulation protein SB
HHGCEAIN_01483 1.7e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HHGCEAIN_01484 2.4e-173 pit P phosphate transporter
HHGCEAIN_01485 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HHGCEAIN_01486 1.4e-240 steT E amino acid
HHGCEAIN_01487 5.3e-178 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HHGCEAIN_01488 5.2e-298 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HHGCEAIN_01489 1.2e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HHGCEAIN_01491 5e-198 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHGCEAIN_01492 2.3e-263 yubD P Major Facilitator Superfamily
HHGCEAIN_01493 3.6e-154 dppA E D-aminopeptidase
HHGCEAIN_01494 3.5e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHGCEAIN_01495 5.3e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHGCEAIN_01496 3e-182 dppD P Belongs to the ABC transporter superfamily
HHGCEAIN_01497 1.3e-309 dppE E ABC transporter substrate-binding protein
HHGCEAIN_01498 1.9e-172 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HHGCEAIN_01499 1.1e-190 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HHGCEAIN_01500 2.4e-156 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HHGCEAIN_01501 4.4e-180 ykfD E Belongs to the ABC transporter superfamily
HHGCEAIN_01502 1.4e-200 pgl 3.1.1.31 G 6-phosphogluconolactonase
HHGCEAIN_01503 1.5e-131 ykgA E Amidinotransferase
HHGCEAIN_01504 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HHGCEAIN_01505 4.4e-92 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HHGCEAIN_01506 1.2e-48 ykkC P Multidrug resistance protein
HHGCEAIN_01507 1e-48 ykkD P Multidrug resistance protein
HHGCEAIN_01508 4.4e-166 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HHGCEAIN_01509 4.4e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHGCEAIN_01510 3.3e-220 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HHGCEAIN_01511 4.1e-69 ohrA O Organic hydroperoxide resistance protein
HHGCEAIN_01512 7.5e-78 ohrR K COG1846 Transcriptional regulators
HHGCEAIN_01513 7.9e-70 ohrB O Organic hydroperoxide resistance protein
HHGCEAIN_01514 2.9e-51 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HHGCEAIN_01516 6e-205 M Glycosyl transferase family 2
HHGCEAIN_01517 1.6e-106 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
HHGCEAIN_01518 4e-207 hcaT 1.5.1.2 EGP Major facilitator Superfamily
HHGCEAIN_01519 9.9e-118 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HHGCEAIN_01520 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HHGCEAIN_01521 6.8e-173 isp O Belongs to the peptidase S8 family
HHGCEAIN_01522 7.8e-141 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HHGCEAIN_01523 7.1e-125 ykoC P Cobalt transport protein
HHGCEAIN_01524 8.6e-277 P ABC transporter, ATP-binding protein
HHGCEAIN_01525 9.3e-96 ykoE S ABC-type cobalt transport system, permease component
HHGCEAIN_01526 1.6e-238 ydhD M Glycosyl hydrolase
HHGCEAIN_01528 3e-235 mgtE P Acts as a magnesium transporter
HHGCEAIN_01529 1.6e-52 tnrA K transcriptional
HHGCEAIN_01530 1.9e-16
HHGCEAIN_01531 5.9e-25 ykoL
HHGCEAIN_01532 4.2e-80 ykoM K transcriptional
HHGCEAIN_01533 4.1e-98 ykoP G polysaccharide deacetylase
HHGCEAIN_01534 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HHGCEAIN_01535 2.8e-149 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HHGCEAIN_01536 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HHGCEAIN_01537 4.4e-95 ykoX S membrane-associated protein
HHGCEAIN_01538 5.4e-128 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HHGCEAIN_01539 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHGCEAIN_01540 4.5e-118 rsgI S Anti-sigma factor N-terminus
HHGCEAIN_01541 9.6e-26 sspD S small acid-soluble spore protein
HHGCEAIN_01542 9.5e-124 ykrK S Domain of unknown function (DUF1836)
HHGCEAIN_01543 3.9e-154 htpX O Belongs to the peptidase M48B family
HHGCEAIN_01544 6.1e-236 ktrB P COG0168 Trk-type K transport systems, membrane components
HHGCEAIN_01545 3e-111 ydfR S Protein of unknown function (DUF421)
HHGCEAIN_01546 1.2e-19 ykzE
HHGCEAIN_01547 3.8e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HHGCEAIN_01548 0.0 kinE 2.7.13.3 T Histidine kinase
HHGCEAIN_01549 5.4e-81 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHGCEAIN_01551 1e-190 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HHGCEAIN_01552 1.6e-219 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HHGCEAIN_01553 7.3e-138 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HHGCEAIN_01554 5.2e-223 mtnE 2.6.1.83 E Aminotransferase
HHGCEAIN_01555 6.9e-223 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HHGCEAIN_01556 1.6e-131 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HHGCEAIN_01557 1.2e-109 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HHGCEAIN_01558 3.6e-91 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HHGCEAIN_01559 4e-11 S Spo0E like sporulation regulatory protein
HHGCEAIN_01560 1e-268 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HHGCEAIN_01561 3.2e-77 ykvE K transcriptional
HHGCEAIN_01562 1.7e-121 motB N Flagellar motor protein
HHGCEAIN_01563 2.5e-136 motA N flagellar motor
HHGCEAIN_01564 0.0 clpE O Belongs to the ClpA ClpB family
HHGCEAIN_01565 6.4e-177 ykvI S membrane
HHGCEAIN_01566 4.9e-13
HHGCEAIN_01567 9.3e-146
HHGCEAIN_01568 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HHGCEAIN_01569 2.9e-78 queD 4.1.2.50, 4.2.3.12 H synthase
HHGCEAIN_01570 7.8e-137 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HHGCEAIN_01571 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HHGCEAIN_01572 1.8e-41 ykvR S Protein of unknown function (DUF3219)
HHGCEAIN_01573 1.7e-24 ykvS S protein conserved in bacteria
HHGCEAIN_01574 2.3e-27
HHGCEAIN_01575 2.6e-104 ykvT 3.5.1.28 M Cell Wall Hydrolase
HHGCEAIN_01576 2.7e-236 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHGCEAIN_01577 8.3e-82 stoA CO thiol-disulfide
HHGCEAIN_01578 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HHGCEAIN_01579 5e-204 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HHGCEAIN_01581 1.9e-170 ykvZ 5.1.1.1 K Transcriptional regulator
HHGCEAIN_01582 8.1e-154 glcT K antiterminator
HHGCEAIN_01583 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHGCEAIN_01584 2.1e-39 ptsH G phosphocarrier protein HPr
HHGCEAIN_01585 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHGCEAIN_01586 6.7e-37 splA S Transcriptional regulator
HHGCEAIN_01587 1.8e-192 splB 4.1.99.14 L Spore photoproduct lyase
HHGCEAIN_01588 3.1e-255 mcpC NT chemotaxis protein
HHGCEAIN_01589 2.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HHGCEAIN_01590 1.6e-48
HHGCEAIN_01591 2.2e-113 ykwD J protein with SCP PR1 domains
HHGCEAIN_01592 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HHGCEAIN_01593 7.1e-288 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
HHGCEAIN_01594 5.7e-214 patA 2.6.1.1 E Aminotransferase
HHGCEAIN_01595 1.4e-09
HHGCEAIN_01596 2.2e-165 cheV 2.7.13.3 T Chemotaxis protein CheV
HHGCEAIN_01597 3.2e-83 ykyB S YkyB-like protein
HHGCEAIN_01598 9.9e-236 ykuC EGP Major facilitator Superfamily
HHGCEAIN_01599 5.1e-87 ykuD S protein conserved in bacteria
HHGCEAIN_01600 7.5e-147 ykuE S Metallophosphoesterase
HHGCEAIN_01601 5.6e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHGCEAIN_01603 1.5e-230 ykuI T Diguanylate phosphodiesterase
HHGCEAIN_01604 2e-36 ykuJ S protein conserved in bacteria
HHGCEAIN_01605 1.7e-90 ykuK S Ribonuclease H-like
HHGCEAIN_01606 7.3e-26 ykzF S Antirepressor AbbA
HHGCEAIN_01607 5.1e-75 ykuL S CBS domain
HHGCEAIN_01608 2.3e-167 ccpC K Transcriptional regulator
HHGCEAIN_01609 2.4e-86 fld C Flavodoxin
HHGCEAIN_01610 8.6e-162 ykuO
HHGCEAIN_01611 1.3e-73 fld C Flavodoxin
HHGCEAIN_01612 4.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HHGCEAIN_01613 6.7e-212 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HHGCEAIN_01614 1.8e-37 ykuS S Belongs to the UPF0180 family
HHGCEAIN_01615 1.6e-138 ykuT M Mechanosensitive ion channel
HHGCEAIN_01617 6.4e-17 ykuV CO thiol-disulfide
HHGCEAIN_01618 2.5e-44 ykuV CO thiol-disulfide
HHGCEAIN_01620 3.8e-97 rok K Repressor of ComK
HHGCEAIN_01621 3.3e-146 yknT
HHGCEAIN_01622 2.2e-100 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HHGCEAIN_01623 4.1e-184 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HHGCEAIN_01624 1.5e-239 moeA 2.10.1.1 H molybdopterin
HHGCEAIN_01625 1.7e-85 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HHGCEAIN_01626 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HHGCEAIN_01627 4.1e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HHGCEAIN_01628 7.3e-100 yknW S Yip1 domain
HHGCEAIN_01629 9.9e-155 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHGCEAIN_01630 5.1e-122 macB V ABC transporter, ATP-binding protein
HHGCEAIN_01631 4e-207 yknZ V ABC transporter (permease)
HHGCEAIN_01632 4.3e-130 fruR K Transcriptional regulator
HHGCEAIN_01633 7.1e-164 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HHGCEAIN_01634 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HHGCEAIN_01635 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HHGCEAIN_01636 6.4e-36 ykoA
HHGCEAIN_01637 5.5e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HHGCEAIN_01638 1.3e-157 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHGCEAIN_01639 9.5e-236 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HHGCEAIN_01640 1.1e-12 S Uncharacterized protein YkpC
HHGCEAIN_01641 7.7e-183 mreB D Rod-share determining protein MreBH
HHGCEAIN_01642 1e-44 abrB K of stationary sporulation gene expression
HHGCEAIN_01643 9.1e-237 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HHGCEAIN_01644 1.6e-146 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HHGCEAIN_01645 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
HHGCEAIN_01646 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HHGCEAIN_01647 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHGCEAIN_01648 5.3e-30 ykzG S Belongs to the UPF0356 family
HHGCEAIN_01649 2.5e-141 ykrA S hydrolases of the HAD superfamily
HHGCEAIN_01650 1.6e-97 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHGCEAIN_01652 3e-66 recN L Putative cell-wall binding lipoprotein
HHGCEAIN_01653 3.8e-183 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHGCEAIN_01654 1.2e-177 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHGCEAIN_01655 2.1e-225 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHGCEAIN_01656 5.9e-242 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HHGCEAIN_01657 6.1e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HHGCEAIN_01658 1.4e-126 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
HHGCEAIN_01659 5.2e-273 speA 4.1.1.19 E Arginine
HHGCEAIN_01660 5.9e-42 yktA S Belongs to the UPF0223 family
HHGCEAIN_01661 5.4e-118 yktB S Belongs to the UPF0637 family
HHGCEAIN_01662 6.3e-24 ykzI
HHGCEAIN_01663 5.1e-150 suhB 3.1.3.25 G Inositol monophosphatase
HHGCEAIN_01664 1.6e-70 ykzC S Acetyltransferase (GNAT) family
HHGCEAIN_01665 3e-287 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HHGCEAIN_01666 5.6e-26 ylaA
HHGCEAIN_01667 1.7e-13 sigC S Putative zinc-finger
HHGCEAIN_01668 2e-37 ylaE
HHGCEAIN_01669 6.7e-24 S Family of unknown function (DUF5325)
HHGCEAIN_01670 0.0 typA T GTP-binding protein TypA
HHGCEAIN_01671 6.6e-48 ylaH S YlaH-like protein
HHGCEAIN_01672 1.5e-32 ylaI S protein conserved in bacteria
HHGCEAIN_01673 6.1e-98 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHGCEAIN_01674 7.8e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HHGCEAIN_01675 2.2e-79 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HHGCEAIN_01676 1.3e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
HHGCEAIN_01677 8.7e-44 ylaN S Belongs to the UPF0358 family
HHGCEAIN_01678 1.1e-209 ftsW D Belongs to the SEDS family
HHGCEAIN_01679 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HHGCEAIN_01680 2.5e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HHGCEAIN_01681 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HHGCEAIN_01682 2.6e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HHGCEAIN_01683 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HHGCEAIN_01684 1.5e-109 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HHGCEAIN_01685 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HHGCEAIN_01686 1.9e-161 ctaG S cytochrome c oxidase
HHGCEAIN_01687 4.6e-58 ylbA S YugN-like family
HHGCEAIN_01688 1.2e-71 ylbB T COG0517 FOG CBS domain
HHGCEAIN_01689 6.4e-193 ylbC S protein with SCP PR1 domains
HHGCEAIN_01690 1.5e-52 ylbD S Putative coat protein
HHGCEAIN_01691 8.8e-37 ylbE S YlbE-like protein
HHGCEAIN_01692 2.5e-69 ylbF S Belongs to the UPF0342 family
HHGCEAIN_01693 1e-41 ylbG S UPF0298 protein
HHGCEAIN_01694 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
HHGCEAIN_01695 2.1e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHGCEAIN_01696 3.4e-209 ylbJ S Sporulation integral membrane protein YlbJ
HHGCEAIN_01697 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HHGCEAIN_01698 2.6e-183 ylbL T Belongs to the peptidase S16 family
HHGCEAIN_01699 2.2e-220 ylbM S Belongs to the UPF0348 family
HHGCEAIN_01700 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
HHGCEAIN_01701 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HHGCEAIN_01702 5e-70 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HHGCEAIN_01703 5.8e-88 ylbP K n-acetyltransferase
HHGCEAIN_01704 2.5e-148 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHGCEAIN_01705 1.1e-300 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HHGCEAIN_01706 1.2e-77 mraZ K Belongs to the MraZ family
HHGCEAIN_01707 5.6e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHGCEAIN_01708 2.4e-51 ftsL D Essential cell division protein
HHGCEAIN_01709 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HHGCEAIN_01710 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HHGCEAIN_01711 3.7e-279 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHGCEAIN_01712 1.4e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHGCEAIN_01713 6.7e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHGCEAIN_01714 2.2e-185 spoVE D Belongs to the SEDS family
HHGCEAIN_01715 1.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHGCEAIN_01716 1.3e-165 murB 1.3.1.98 M cell wall formation
HHGCEAIN_01717 1.3e-126 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHGCEAIN_01718 1.7e-227 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHGCEAIN_01719 7.5e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHGCEAIN_01720 0.0 bpr O COG1404 Subtilisin-like serine proteases
HHGCEAIN_01721 7.8e-158 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HHGCEAIN_01722 1.2e-116 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHGCEAIN_01723 3.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHGCEAIN_01724 7.9e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HHGCEAIN_01725 7e-242 argE 3.5.1.16 E Acetylornithine deacetylase
HHGCEAIN_01726 2.2e-38 ylmC S sporulation protein
HHGCEAIN_01727 5.2e-153 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HHGCEAIN_01728 4.1e-119 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HHGCEAIN_01729 5.7e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHGCEAIN_01730 5.2e-41 yggT S membrane
HHGCEAIN_01731 6.3e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HHGCEAIN_01732 8.9e-68 divIVA D Cell division initiation protein
HHGCEAIN_01733 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHGCEAIN_01734 3.8e-63 dksA T COG1734 DnaK suppressor protein
HHGCEAIN_01735 1.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHGCEAIN_01736 1.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHGCEAIN_01737 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHGCEAIN_01738 1.1e-229 pyrP F Xanthine uracil
HHGCEAIN_01739 3.7e-160 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HHGCEAIN_01740 2.2e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHGCEAIN_01741 3.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HHGCEAIN_01742 0.0 carB 6.3.5.5 F Belongs to the CarB family
HHGCEAIN_01743 1.1e-138 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HHGCEAIN_01744 1.6e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHGCEAIN_01745 1.7e-123 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHGCEAIN_01746 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHGCEAIN_01748 6.1e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HHGCEAIN_01749 8e-175 cysP P phosphate transporter
HHGCEAIN_01750 3.6e-221 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HHGCEAIN_01751 2.1e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HHGCEAIN_01752 1.4e-139 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HHGCEAIN_01753 3.2e-136 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HHGCEAIN_01754 4.3e-75 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HHGCEAIN_01755 3.4e-267 amyA 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HHGCEAIN_01756 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HHGCEAIN_01757 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HHGCEAIN_01758 2.3e-151 yloC S stress-induced protein
HHGCEAIN_01759 1.5e-40 ylzA S Belongs to the UPF0296 family
HHGCEAIN_01760 8.9e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HHGCEAIN_01761 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHGCEAIN_01762 3.5e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHGCEAIN_01763 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHGCEAIN_01764 4.7e-82 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHGCEAIN_01765 6.4e-168 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHGCEAIN_01766 4.9e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHGCEAIN_01767 1.7e-204 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HHGCEAIN_01768 7.1e-133 stp 3.1.3.16 T phosphatase
HHGCEAIN_01769 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HHGCEAIN_01770 3.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHGCEAIN_01771 2.2e-114 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HHGCEAIN_01772 1.8e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
HHGCEAIN_01773 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HHGCEAIN_01774 6.1e-58 asp S protein conserved in bacteria
HHGCEAIN_01775 1.3e-299 yloV S kinase related to dihydroxyacetone kinase
HHGCEAIN_01776 4.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HHGCEAIN_01777 3.9e-154 sdaAA 4.3.1.17 E L-serine dehydratase
HHGCEAIN_01778 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHGCEAIN_01779 2.2e-91 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HHGCEAIN_01780 2.3e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHGCEAIN_01781 1.9e-167 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HHGCEAIN_01782 1.1e-127 IQ reductase
HHGCEAIN_01783 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHGCEAIN_01784 7.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHGCEAIN_01785 0.0 smc D Required for chromosome condensation and partitioning
HHGCEAIN_01786 5.9e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHGCEAIN_01787 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHGCEAIN_01788 9e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHGCEAIN_01789 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HHGCEAIN_01790 1.7e-35 ylqC S Belongs to the UPF0109 family
HHGCEAIN_01791 1.1e-60 ylqD S YlqD protein
HHGCEAIN_01792 1.4e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHGCEAIN_01793 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HHGCEAIN_01794 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHGCEAIN_01795 5.5e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHGCEAIN_01796 5.5e-125 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHGCEAIN_01797 5.4e-266 ylqG
HHGCEAIN_01798 1.6e-42 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HHGCEAIN_01799 2.6e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HHGCEAIN_01800 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHGCEAIN_01801 1.7e-162 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HHGCEAIN_01802 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHGCEAIN_01803 5.3e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HHGCEAIN_01804 3.3e-169 xerC L tyrosine recombinase XerC
HHGCEAIN_01805 2.2e-91 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HHGCEAIN_01806 1.4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HHGCEAIN_01807 2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HHGCEAIN_01808 7.8e-51 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HHGCEAIN_01809 9.9e-74 flgC N Belongs to the flagella basal body rod proteins family
HHGCEAIN_01810 2.5e-31 fliE N Flagellar hook-basal body
HHGCEAIN_01811 2.7e-251 fliF N The M ring may be actively involved in energy transduction
HHGCEAIN_01812 1.7e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HHGCEAIN_01813 1.4e-85 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HHGCEAIN_01814 2.7e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HHGCEAIN_01815 1.7e-70 fliJ N Flagellar biosynthesis chaperone
HHGCEAIN_01816 1.2e-37 ylxF S MgtE intracellular N domain
HHGCEAIN_01817 5.5e-189 fliK N Flagellar hook-length control protein
HHGCEAIN_01818 2.7e-68 flgD N Flagellar basal body rod modification protein
HHGCEAIN_01819 5.4e-136 flgG N Flagellar basal body rod
HHGCEAIN_01820 5.1e-56 fliL N Controls the rotational direction of flagella during chemotaxis
HHGCEAIN_01821 7.8e-180 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HHGCEAIN_01822 3.8e-175 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HHGCEAIN_01823 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HHGCEAIN_01824 3.3e-110 fliZ N Flagellar biosynthesis protein, FliO
HHGCEAIN_01825 3.7e-109 fliP N Plays a role in the flagellum-specific transport system
HHGCEAIN_01826 7.5e-37 fliQ N Role in flagellar biosynthesis
HHGCEAIN_01827 3.2e-128 fliR N Flagellar biosynthetic protein FliR
HHGCEAIN_01828 1.1e-187 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHGCEAIN_01829 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHGCEAIN_01830 2.9e-156 flhF N Flagellar biosynthesis regulator FlhF
HHGCEAIN_01831 4.3e-153 flhG D Belongs to the ParA family
HHGCEAIN_01832 4.3e-173 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HHGCEAIN_01833 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HHGCEAIN_01834 2.5e-80 cheW NT COG0835 Chemotaxis signal transduction protein
HHGCEAIN_01835 7e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HHGCEAIN_01836 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HHGCEAIN_01837 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHGCEAIN_01838 1.7e-47 ylxL
HHGCEAIN_01839 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HHGCEAIN_01840 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHGCEAIN_01841 1.6e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HHGCEAIN_01842 2.1e-89 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHGCEAIN_01843 1.3e-142 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHGCEAIN_01844 8.4e-137 cdsA 2.7.7.41 S Belongs to the CDS family
HHGCEAIN_01845 2.3e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HHGCEAIN_01846 4.2e-231 rasP M zinc metalloprotease
HHGCEAIN_01847 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHGCEAIN_01848 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHGCEAIN_01849 1.9e-80 rimP S Required for maturation of 30S ribosomal subunits
HHGCEAIN_01850 3.5e-205 nusA K Participates in both transcription termination and antitermination
HHGCEAIN_01851 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
HHGCEAIN_01852 1.8e-47 ylxQ J ribosomal protein
HHGCEAIN_01853 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHGCEAIN_01854 8.6e-44 ylxP S protein conserved in bacteria
HHGCEAIN_01855 3.7e-51 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHGCEAIN_01856 2.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHGCEAIN_01857 1.4e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HHGCEAIN_01858 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHGCEAIN_01859 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HHGCEAIN_01860 1.4e-178 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HHGCEAIN_01861 2e-233 pepR S Belongs to the peptidase M16 family
HHGCEAIN_01862 2.6e-42 ymxH S YlmC YmxH family
HHGCEAIN_01863 9.8e-158 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HHGCEAIN_01864 4.3e-101 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HHGCEAIN_01865 1.1e-189 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHGCEAIN_01866 2.2e-216 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HHGCEAIN_01867 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHGCEAIN_01868 4.7e-302 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHGCEAIN_01869 6.6e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HHGCEAIN_01870 2.6e-29 S YlzJ-like protein
HHGCEAIN_01871 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HHGCEAIN_01872 2e-129 ymfC K Transcriptional regulator
HHGCEAIN_01873 6.2e-225 ymfD EGP Major facilitator Superfamily
HHGCEAIN_01874 5.8e-74 K helix_turn_helix multiple antibiotic resistance protein
HHGCEAIN_01875 0.0 ydgH S drug exporters of the RND superfamily
HHGCEAIN_01876 7e-234 ymfF S Peptidase M16
HHGCEAIN_01877 7.3e-239 ymfH S zinc protease
HHGCEAIN_01878 8.1e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HHGCEAIN_01879 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
HHGCEAIN_01880 5.1e-142 ymfK S Protein of unknown function (DUF3388)
HHGCEAIN_01881 6.4e-117 ymfM S protein conserved in bacteria
HHGCEAIN_01882 4.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHGCEAIN_01883 2.1e-230 cinA 3.5.1.42 S Belongs to the CinA family
HHGCEAIN_01884 7.6e-186 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHGCEAIN_01885 2.4e-180 pbpX V Beta-lactamase
HHGCEAIN_01886 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
HHGCEAIN_01887 1.9e-152 ymdB S protein conserved in bacteria
HHGCEAIN_01888 1.2e-36 spoVS S Stage V sporulation protein S
HHGCEAIN_01889 3.1e-195 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HHGCEAIN_01890 7e-212 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HHGCEAIN_01891 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HHGCEAIN_01892 1.2e-65 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HHGCEAIN_01893 2.1e-86 cotE S Spore coat protein
HHGCEAIN_01894 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHGCEAIN_01895 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHGCEAIN_01896 2.9e-125 pksB 3.1.2.6 S Polyketide biosynthesis
HHGCEAIN_01897 8.6e-159 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HHGCEAIN_01898 6.9e-173 pksD Q Acyl transferase domain
HHGCEAIN_01899 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HHGCEAIN_01900 8.5e-35 acpK IQ Phosphopantetheine attachment site
HHGCEAIN_01901 1.5e-241 pksG 2.3.3.10 I synthase
HHGCEAIN_01902 8.8e-139 pksH 4.2.1.18 I enoyl-CoA hydratase
HHGCEAIN_01903 6.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HHGCEAIN_01904 0.0 rhiB IQ polyketide synthase
HHGCEAIN_01905 0.0 Q Polyketide synthase of type I
HHGCEAIN_01906 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HHGCEAIN_01907 0.0 dhbF IQ polyketide synthase
HHGCEAIN_01908 0.0 pks13 HQ Beta-ketoacyl synthase
HHGCEAIN_01909 1.4e-223 cypA C Cytochrome P450
HHGCEAIN_01910 5.2e-72 nucB M Deoxyribonuclease NucA/NucB
HHGCEAIN_01911 3.4e-116 yoaK S Membrane
HHGCEAIN_01912 1.6e-61 ymzB
HHGCEAIN_01913 3.1e-248 aprX O Belongs to the peptidase S8 family
HHGCEAIN_01915 1e-117 ymaC S Replication protein
HHGCEAIN_01916 1.4e-75 ymaD O redox protein, regulator of disulfide bond formation
HHGCEAIN_01917 9.8e-53 ebrB P Small Multidrug Resistance protein
HHGCEAIN_01918 2.5e-47 ebrA P Small Multidrug Resistance protein
HHGCEAIN_01920 2.8e-43 ymaF S YmaF family
HHGCEAIN_01921 6.7e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHGCEAIN_01922 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HHGCEAIN_01923 2.6e-40
HHGCEAIN_01924 7.9e-21 ymzA
HHGCEAIN_01925 2.3e-58 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HHGCEAIN_01926 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHGCEAIN_01927 2.6e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHGCEAIN_01928 1.3e-103 ymaB S MutT family
HHGCEAIN_01929 4.8e-105 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HHGCEAIN_01930 8.6e-176 spoVK O stage V sporulation protein K
HHGCEAIN_01931 3.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHGCEAIN_01932 5e-240 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HHGCEAIN_01933 8.8e-66 glnR K transcriptional
HHGCEAIN_01934 1.2e-260 glnA 6.3.1.2 E glutamine synthetase
HHGCEAIN_01935 2.4e-153 L Belongs to the 'phage' integrase family
HHGCEAIN_01936 3e-11
HHGCEAIN_01937 6.3e-78 yokF 3.1.31.1 L RNA catabolic process
HHGCEAIN_01938 1.5e-92 G SMI1-KNR4 cell-wall
HHGCEAIN_01939 1.5e-148 V HNH endonuclease
HHGCEAIN_01940 1.4e-288 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HHGCEAIN_01941 2.2e-52 S SMI1-KNR4 cell-wall
HHGCEAIN_01943 5.8e-127 yunB S Sporulation protein YunB (Spo_YunB)
HHGCEAIN_01944 1.5e-39 S YolD-like protein
HHGCEAIN_01945 1.6e-222 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHGCEAIN_01946 4.3e-67 2.7.7.80 H ThiF family
HHGCEAIN_01947 2.6e-52 cmoA 2.8.1.10 Q Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM)
HHGCEAIN_01948 7.6e-36 EGP Major facilitator Superfamily
HHGCEAIN_01949 7.6e-211 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HHGCEAIN_01950 1.5e-116 3.2.1.8 G Glycosyl hydrolases family 11
HHGCEAIN_01951 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HHGCEAIN_01952 5.9e-74 K Transcriptional regulator, TetR family
HHGCEAIN_01953 2.2e-177 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HHGCEAIN_01955 2.5e-195 S aspartate phosphatase
HHGCEAIN_01957 0.0 L Transposase and inactivated derivatives, TnpA family
HHGCEAIN_01958 7.1e-85 L resolvase
HHGCEAIN_01959 1.3e-78
HHGCEAIN_01961 6e-26 S Protein of unknown function (DUF1657)
HHGCEAIN_01962 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHGCEAIN_01963 2.6e-80 spoVAC S stage V sporulation protein AC
HHGCEAIN_01964 1e-195 spoVAD I Stage V sporulation protein AD
HHGCEAIN_01965 8.5e-57 spoVAE S stage V sporulation protein
HHGCEAIN_01966 5.8e-29 S Protein of unknown function (DUF1657)
HHGCEAIN_01967 4.7e-149 yetF1 S membrane
HHGCEAIN_01968 1.2e-70 S Protein of unknown function (DUF421)
HHGCEAIN_01969 2.7e-285 clsA_1 I PLD-like domain
HHGCEAIN_01970 2.5e-92 S Protein of unknown function (DUF421)
HHGCEAIN_01972 1.7e-66 S DinB family
HHGCEAIN_01973 8.5e-182 adhP 1.1.1.1 C alcohol dehydrogenase
HHGCEAIN_01974 4e-11
HHGCEAIN_01976 2.9e-26 S Protein of unknown function (DUF4025)
HHGCEAIN_01977 1.1e-10 ywlA S Uncharacterised protein family (UPF0715)
HHGCEAIN_01978 1.1e-128 yoaP 3.1.3.18 K YoaP-like
HHGCEAIN_01979 1.1e-90 J Acetyltransferase (GNAT) domain
HHGCEAIN_01981 1.4e-34
HHGCEAIN_01983 6.6e-100 ynaE S Domain of unknown function (DUF3885)
HHGCEAIN_01984 9.2e-187 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHGCEAIN_01985 1.1e-115 AA10,CBM73 S Pfam:Chitin_bind_3
HHGCEAIN_01987 3.3e-84 yvgO
HHGCEAIN_01989 0.0 yobO M Pectate lyase superfamily protein
HHGCEAIN_01990 1.3e-32 S TM2 domain
HHGCEAIN_01991 1.7e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HHGCEAIN_01992 3.9e-24 S Domain of unknown function (DUF4177)
HHGCEAIN_01993 9.7e-128 yndL S Replication protein
HHGCEAIN_01995 2e-136 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
HHGCEAIN_01996 5.8e-66 yndM S Protein of unknown function (DUF2512)
HHGCEAIN_01997 1.3e-11 yoaW
HHGCEAIN_01998 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHGCEAIN_01999 1.2e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HHGCEAIN_02000 1.6e-109 yneB L resolvase
HHGCEAIN_02001 9.8e-33 ynzC S UPF0291 protein
HHGCEAIN_02002 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHGCEAIN_02003 7.7e-79 yneE S Sporulation inhibitor of replication protein sirA
HHGCEAIN_02004 2.3e-28 yneF S UPF0154 protein
HHGCEAIN_02005 8.9e-23 ynzD S Spo0E like sporulation regulatory protein
HHGCEAIN_02006 1.2e-121 ccdA O cytochrome c biogenesis protein
HHGCEAIN_02007 1.2e-56 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HHGCEAIN_02008 5.6e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HHGCEAIN_02009 2.8e-70 yneK S Protein of unknown function (DUF2621)
HHGCEAIN_02010 5.7e-59 hspX O Spore coat protein
HHGCEAIN_02011 2.3e-19 sspP S Belongs to the SspP family
HHGCEAIN_02012 7.5e-15 sspO S Belongs to the SspO family
HHGCEAIN_02013 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HHGCEAIN_02014 3.6e-88 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HHGCEAIN_02016 1.1e-31 tlp S Belongs to the Tlp family
HHGCEAIN_02017 7.7e-73 yneP S Thioesterase-like superfamily
HHGCEAIN_02018 1.9e-49 yneQ
HHGCEAIN_02019 3.4e-43 yneR S Belongs to the HesB IscA family
HHGCEAIN_02020 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHGCEAIN_02021 3.3e-68 yccU S CoA-binding protein
HHGCEAIN_02022 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHGCEAIN_02023 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHGCEAIN_02024 4.6e-13
HHGCEAIN_02025 1.2e-39 ynfC
HHGCEAIN_02026 4e-246 agcS E Sodium alanine symporter
HHGCEAIN_02027 5.2e-22 yndG S DoxX-like family
HHGCEAIN_02028 2e-77 yndH S Domain of unknown function (DUF4166)
HHGCEAIN_02029 4.6e-275 yndJ S YndJ-like protein
HHGCEAIN_02030 1.2e-49 S Domain of unknown function (DUF4870)
HHGCEAIN_02031 3.2e-216 T PhoQ Sensor
HHGCEAIN_02032 3.4e-121 T Transcriptional regulatory protein, C terminal
HHGCEAIN_02033 6.5e-240 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HHGCEAIN_02034 2.8e-277 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HHGCEAIN_02035 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHGCEAIN_02036 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHGCEAIN_02037 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHGCEAIN_02038 4.5e-206 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HHGCEAIN_02039 5.8e-122 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HHGCEAIN_02040 5.4e-105 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HHGCEAIN_02041 2.3e-114 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HHGCEAIN_02042 2.5e-164 bioI 1.14.14.46 C Cytochrome P450
HHGCEAIN_02043 8.5e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HHGCEAIN_02044 4e-122 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HHGCEAIN_02045 3.9e-199 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HHGCEAIN_02046 1.6e-252 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HHGCEAIN_02047 8.5e-134 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HHGCEAIN_02048 1.6e-67 yngA S membrane
HHGCEAIN_02049 8.6e-154 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HHGCEAIN_02050 1.6e-103 yngC S SNARE associated Golgi protein
HHGCEAIN_02051 1.1e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HHGCEAIN_02052 5.6e-133 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HHGCEAIN_02053 1.6e-163 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HHGCEAIN_02054 1.2e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HHGCEAIN_02055 9e-240 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HHGCEAIN_02056 2.7e-252 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHGCEAIN_02057 9.2e-36 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHGCEAIN_02058 5e-207 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HHGCEAIN_02059 5.6e-294 yngK T Glycosyl hydrolase-like 10
HHGCEAIN_02060 5.1e-63 yngL S Protein of unknown function (DUF1360)
HHGCEAIN_02061 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
HHGCEAIN_02062 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHGCEAIN_02063 6.8e-257 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HHGCEAIN_02064 3.4e-180 yoxA 5.1.3.3 G Aldose 1-epimerase
HHGCEAIN_02065 9.9e-242 yoeA V MATE efflux family protein
HHGCEAIN_02066 6.1e-94 yoeB S IseA DL-endopeptidase inhibitor
HHGCEAIN_02068 1.9e-95 L Integrase
HHGCEAIN_02069 1.1e-33 yoeD G Helix-turn-helix domain
HHGCEAIN_02070 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HHGCEAIN_02071 5.4e-188 ybcL EGP Major facilitator Superfamily
HHGCEAIN_02072 6.7e-50 ybzH K Helix-turn-helix domain
HHGCEAIN_02073 1.1e-270 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHGCEAIN_02074 1.4e-289 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HHGCEAIN_02075 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HHGCEAIN_02076 3.6e-147 gltC K Transcriptional regulator
HHGCEAIN_02077 5.1e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHGCEAIN_02078 6.1e-135 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHGCEAIN_02079 3.6e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HHGCEAIN_02080 6.9e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHGCEAIN_02081 1.3e-37 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHGCEAIN_02082 1.7e-115 yoxB
HHGCEAIN_02083 2.5e-92 S Protein of unknown function (DUF421)
HHGCEAIN_02084 2.7e-285 clsA_1 I PLD-like domain
HHGCEAIN_02085 1.2e-70 S Protein of unknown function (DUF421)
HHGCEAIN_02086 4.7e-149 yetF1 S membrane
HHGCEAIN_02087 5.8e-29 S Protein of unknown function (DUF1657)
HHGCEAIN_02088 8.5e-57 spoVAE S stage V sporulation protein
HHGCEAIN_02089 1e-195 spoVAD I Stage V sporulation protein AD
HHGCEAIN_02090 2.6e-80 spoVAC S stage V sporulation protein AC
HHGCEAIN_02091 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHGCEAIN_02092 6e-26 S Protein of unknown function (DUF1657)
HHGCEAIN_02094 1.3e-78
HHGCEAIN_02095 7.1e-85 L resolvase
HHGCEAIN_02096 0.0 L Transposase and inactivated derivatives, TnpA family
HHGCEAIN_02097 2.2e-194 yoaB EGP Major facilitator Superfamily
HHGCEAIN_02098 1.2e-264 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
HHGCEAIN_02099 1e-159 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHGCEAIN_02100 1e-09 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHGCEAIN_02101 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHGCEAIN_02102 5.7e-27 yoaF
HHGCEAIN_02104 1.1e-93 hpr K helix_turn_helix multiple antibiotic resistance protein
HHGCEAIN_02105 1.1e-28
HHGCEAIN_02108 4.6e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HHGCEAIN_02109 3.4e-121 yobQ K helix_turn_helix, arabinose operon control protein
HHGCEAIN_02110 7e-85 yobS K Transcriptional regulator
HHGCEAIN_02111 8.8e-125 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HHGCEAIN_02112 2.1e-91 yobW
HHGCEAIN_02113 7.6e-55 czrA K transcriptional
HHGCEAIN_02114 3.3e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HHGCEAIN_02115 1.4e-90 yozB S membrane
HHGCEAIN_02116 1.9e-133 yocB J Protein required for attachment to host cells
HHGCEAIN_02117 3.4e-91 yocC
HHGCEAIN_02118 5.3e-181 yocD 3.4.17.13 V peptidase S66
HHGCEAIN_02120 2.1e-112 yocH CBM50 M COG1388 FOG LysM repeat
HHGCEAIN_02121 0.0 recQ 3.6.4.12 L DNA helicase
HHGCEAIN_02123 1.1e-110 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HHGCEAIN_02124 2e-56 dksA T general stress protein
HHGCEAIN_02125 6.3e-10 yocL
HHGCEAIN_02126 9.8e-09
HHGCEAIN_02127 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HHGCEAIN_02128 2e-29 yozN
HHGCEAIN_02129 2.5e-36 yocN
HHGCEAIN_02130 2.4e-56 yozO S Bacterial PH domain
HHGCEAIN_02132 1.6e-31 yozC
HHGCEAIN_02133 5.1e-284 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HHGCEAIN_02134 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HHGCEAIN_02135 8.1e-162 sodA 1.15.1.1 P Superoxide dismutase
HHGCEAIN_02136 7.1e-229 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHGCEAIN_02137 1.8e-157 yocS S -transporter
HHGCEAIN_02138 8e-123 S Metallo-beta-lactamase superfamily
HHGCEAIN_02139 2.9e-184 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HHGCEAIN_02140 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HHGCEAIN_02141 0.0 yojO P Von Willebrand factor
HHGCEAIN_02142 6.5e-162 yojN S ATPase family associated with various cellular activities (AAA)
HHGCEAIN_02143 1.2e-98 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HHGCEAIN_02144 2.1e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HHGCEAIN_02145 5.1e-218 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HHGCEAIN_02146 2.3e-105 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHGCEAIN_02148 1.1e-232 norM V Multidrug efflux pump
HHGCEAIN_02149 6.2e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HHGCEAIN_02150 9.6e-126 yojG S deacetylase
HHGCEAIN_02151 3.7e-60 yojF S Protein of unknown function (DUF1806)
HHGCEAIN_02152 6.4e-23
HHGCEAIN_02153 2.6e-158 rarD S -transporter
HHGCEAIN_02154 8.9e-78 yozR S COG0071 Molecular chaperone (small heat shock protein)
HHGCEAIN_02156 6.8e-63 yodA S tautomerase
HHGCEAIN_02157 3.5e-52 yodB K transcriptional
HHGCEAIN_02158 2.8e-103 yodC C nitroreductase
HHGCEAIN_02159 7.2e-92 mhqD S Carboxylesterase
HHGCEAIN_02160 1.8e-167 yodE E COG0346 Lactoylglutathione lyase and related lyases
HHGCEAIN_02161 3.1e-19 S Protein of unknown function (DUF3311)
HHGCEAIN_02162 3.2e-262 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHGCEAIN_02163 2.1e-266 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
HHGCEAIN_02164 1.6e-282 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHGCEAIN_02165 3.8e-128 yydK K Transcriptional regulator
HHGCEAIN_02166 5.5e-248 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HHGCEAIN_02167 4e-95 yodH Q Methyltransferase
HHGCEAIN_02168 1e-19 yodI
HHGCEAIN_02169 7.6e-141 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HHGCEAIN_02170 7.7e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HHGCEAIN_02172 3.3e-55 yodL S YodL-like
HHGCEAIN_02173 4.4e-101 yodM 3.6.1.27 I Acid phosphatase homologues
HHGCEAIN_02174 1.8e-23 yozD S YozD-like protein
HHGCEAIN_02176 5.6e-121 yodN
HHGCEAIN_02177 6.1e-51 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHGCEAIN_02178 3.4e-35 yozE S Belongs to the UPF0346 family
HHGCEAIN_02179 1.1e-43 yokU S YokU-like protein, putative antitoxin
HHGCEAIN_02180 1.6e-274 kamA 5.4.3.2 E lysine 2,3-aminomutase
HHGCEAIN_02181 1.4e-140 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HHGCEAIN_02182 1e-248 yodQ 3.5.1.16 E Acetylornithine deacetylase
HHGCEAIN_02183 2.7e-118 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HHGCEAIN_02184 1.5e-121 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HHGCEAIN_02185 3e-235 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHGCEAIN_02187 5.4e-64 yosT L Bacterial transcription activator, effector binding domain
HHGCEAIN_02189 1.3e-137 yiiD K acetyltransferase
HHGCEAIN_02190 7e-226 cgeD M maturation of the outermost layer of the spore
HHGCEAIN_02191 1.4e-36 cgeC
HHGCEAIN_02192 3.1e-48 cgeA
HHGCEAIN_02193 7.7e-169 cgeB S Spore maturation protein
HHGCEAIN_02194 4.1e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HHGCEAIN_02195 1.2e-69 4.2.1.115 GM Polysaccharide biosynthesis protein
HHGCEAIN_02198 1.9e-121 lldD 1.13.12.4 C FMN-dependent dehydrogenase
HHGCEAIN_02200 1.9e-13 S Regulatory protein YrvL
HHGCEAIN_02201 6.4e-211 yokA L Recombinase
HHGCEAIN_02202 1.2e-100 4.2.1.115 GM Polysaccharide biosynthesis protein
HHGCEAIN_02203 6.4e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HHGCEAIN_02204 4.3e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHGCEAIN_02205 8.9e-66 ypoP K transcriptional
HHGCEAIN_02206 1.7e-94 ypmS S protein conserved in bacteria
HHGCEAIN_02207 9.5e-130 ypmR E GDSL-like Lipase/Acylhydrolase
HHGCEAIN_02208 2e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HHGCEAIN_02209 7.5e-39 ypmP S Protein of unknown function (DUF2535)
HHGCEAIN_02210 1.3e-240 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHGCEAIN_02211 3.8e-163 pspF K Transcriptional regulator
HHGCEAIN_02212 6.6e-108 hlyIII S protein, Hemolysin III
HHGCEAIN_02213 1.7e-108 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HHGCEAIN_02214 7.8e-85 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHGCEAIN_02215 2.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHGCEAIN_02216 3e-110 ypjP S YpjP-like protein
HHGCEAIN_02217 2.9e-126 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HHGCEAIN_02218 1.7e-75 yphP S Belongs to the UPF0403 family
HHGCEAIN_02219 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HHGCEAIN_02220 6e-152 ypgR C COG0694 Thioredoxin-like proteins and domains
HHGCEAIN_02221 2.3e-89 ypgQ S phosphohydrolase
HHGCEAIN_02222 2.1e-82 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HHGCEAIN_02224 2.8e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HHGCEAIN_02225 1.4e-212 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HHGCEAIN_02226 1e-30 cspD K Cold-shock protein
HHGCEAIN_02227 6.3e-11 degR
HHGCEAIN_02228 2.3e-35 S Protein of unknown function (DUF2564)
HHGCEAIN_02229 3.7e-27 ypeQ S Zinc-finger
HHGCEAIN_02230 2e-118 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HHGCEAIN_02231 5.2e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HHGCEAIN_02232 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
HHGCEAIN_02234 8e-160 polA 2.7.7.7 L 5'3' exonuclease
HHGCEAIN_02236 3.7e-33 ypbS S Protein of unknown function (DUF2533)
HHGCEAIN_02237 0.0 ypbR S Dynamin family
HHGCEAIN_02238 4.8e-85 ypbQ S protein conserved in bacteria
HHGCEAIN_02239 1.2e-194 bcsA Q Naringenin-chalcone synthase
HHGCEAIN_02240 2e-101 J Acetyltransferase (GNAT) domain
HHGCEAIN_02241 6.6e-45 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HHGCEAIN_02242 2.4e-07 S Bacillus cereus group antimicrobial protein
HHGCEAIN_02243 5.1e-232 pbuX F xanthine
HHGCEAIN_02244 2.9e-94 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHGCEAIN_02245 1.9e-286 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HHGCEAIN_02246 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HHGCEAIN_02248 6.6e-22 S YpzG-like protein
HHGCEAIN_02249 2e-74 yqgA
HHGCEAIN_02250 1.3e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HHGCEAIN_02251 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHGCEAIN_02252 5.9e-97 ypsA S Belongs to the UPF0398 family
HHGCEAIN_02253 8.5e-24 cotD S Inner spore coat protein D
HHGCEAIN_02255 7.5e-225 yprB L RNase_H superfamily
HHGCEAIN_02256 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HHGCEAIN_02257 1.3e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HHGCEAIN_02258 4.4e-60 hspX O Belongs to the small heat shock protein (HSP20) family
HHGCEAIN_02259 4.4e-38 yppG S YppG-like protein
HHGCEAIN_02261 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HHGCEAIN_02264 9.2e-178 yppC S Protein of unknown function (DUF2515)
HHGCEAIN_02265 1.2e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHGCEAIN_02266 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHGCEAIN_02267 1.4e-86 ypoC
HHGCEAIN_02268 7.8e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHGCEAIN_02269 3.4e-129 dnaD L DNA replication protein DnaD
HHGCEAIN_02270 7.1e-250 asnS 6.1.1.22 J asparaginyl-tRNA
HHGCEAIN_02271 2.9e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HHGCEAIN_02272 1.4e-73 ypmB S protein conserved in bacteria
HHGCEAIN_02273 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HHGCEAIN_02274 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HHGCEAIN_02275 3.9e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HHGCEAIN_02276 1.2e-152 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HHGCEAIN_02277 2e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HHGCEAIN_02278 4.9e-179 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHGCEAIN_02279 5.6e-209 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHGCEAIN_02280 1.7e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HHGCEAIN_02281 1e-125 bshB1 S proteins, LmbE homologs
HHGCEAIN_02282 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HHGCEAIN_02283 3.8e-145 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHGCEAIN_02284 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HHGCEAIN_02285 4.7e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HHGCEAIN_02286 2.5e-222 oxdC 4.1.1.2 G Oxalate decarboxylase
HHGCEAIN_02287 1.5e-138 ypjB S sporulation protein
HHGCEAIN_02288 1.5e-98 ypjA S membrane
HHGCEAIN_02289 5.7e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HHGCEAIN_02290 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HHGCEAIN_02291 8.7e-95 qcrA C Menaquinol-cytochrome c reductase
HHGCEAIN_02292 8.3e-73 ypiF S Protein of unknown function (DUF2487)
HHGCEAIN_02293 8.1e-99 ypiB S Belongs to the UPF0302 family
HHGCEAIN_02294 1.5e-228 S COG0457 FOG TPR repeat
HHGCEAIN_02295 2.9e-227 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HHGCEAIN_02296 1.8e-201 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HHGCEAIN_02297 3.1e-198 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HHGCEAIN_02298 5.5e-136 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HHGCEAIN_02299 5.6e-225 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HHGCEAIN_02300 3.3e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HHGCEAIN_02301 3e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HHGCEAIN_02302 6.3e-153 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHGCEAIN_02303 5.8e-283 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHGCEAIN_02304 1.7e-58 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HHGCEAIN_02305 6.3e-199 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HHGCEAIN_02306 2.3e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HHGCEAIN_02307 6.3e-137 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HHGCEAIN_02308 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HHGCEAIN_02309 4.8e-196 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHGCEAIN_02310 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HHGCEAIN_02311 1.5e-135 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HHGCEAIN_02312 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HHGCEAIN_02313 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
HHGCEAIN_02314 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHGCEAIN_02315 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HHGCEAIN_02316 1.3e-10 yphF
HHGCEAIN_02317 7.1e-130 yphF
HHGCEAIN_02318 1.5e-16 yphE S Protein of unknown function (DUF2768)
HHGCEAIN_02319 5.2e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HHGCEAIN_02320 1.8e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HHGCEAIN_02321 2.4e-99 yphA
HHGCEAIN_02322 4.7e-08 S YpzI-like protein
HHGCEAIN_02323 1.5e-178 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HHGCEAIN_02324 2.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HHGCEAIN_02325 7.5e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HHGCEAIN_02326 2.5e-12 S Family of unknown function (DUF5359)
HHGCEAIN_02327 1.1e-57 ypfA M Flagellar protein YcgR
HHGCEAIN_02328 2.5e-245 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HHGCEAIN_02329 4.7e-149 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HHGCEAIN_02330 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HHGCEAIN_02331 7.2e-186 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HHGCEAIN_02332 2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HHGCEAIN_02333 2.2e-105 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HHGCEAIN_02334 1.9e-141 ypbG S Calcineurin-like phosphoesterase superfamily domain
HHGCEAIN_02335 1.1e-83 ypbF S Protein of unknown function (DUF2663)
HHGCEAIN_02336 3.7e-60 ypbE M Lysin motif
HHGCEAIN_02337 1.6e-95 ypbD S metal-dependent membrane protease
HHGCEAIN_02338 2.5e-275 recQ 3.6.4.12 L DNA helicase
HHGCEAIN_02339 1.5e-189 ypbB 5.1.3.1 S protein conserved in bacteria
HHGCEAIN_02340 3.6e-41 fer C Ferredoxin
HHGCEAIN_02341 1.6e-92 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHGCEAIN_02342 2.2e-290 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHGCEAIN_02343 2.3e-169 rsiX
HHGCEAIN_02344 2.2e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HHGCEAIN_02345 0.0 resE 2.7.13.3 T Histidine kinase
HHGCEAIN_02346 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHGCEAIN_02347 1.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HHGCEAIN_02348 1.1e-308 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HHGCEAIN_02349 3.4e-97 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HHGCEAIN_02350 6.4e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHGCEAIN_02351 3.8e-88 spmB S Spore maturation protein
HHGCEAIN_02352 1.3e-102 spmA S Spore maturation protein
HHGCEAIN_02353 1.1e-209 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HHGCEAIN_02354 8.1e-82 ypuI S Protein of unknown function (DUF3907)
HHGCEAIN_02355 5.1e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHGCEAIN_02356 3.1e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHGCEAIN_02358 6.2e-88 ypuF S Domain of unknown function (DUF309)
HHGCEAIN_02359 1e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHGCEAIN_02360 5.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HHGCEAIN_02361 2.3e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HHGCEAIN_02362 3.2e-110 ribE 2.5.1.9 H Riboflavin synthase
HHGCEAIN_02363 6.2e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHGCEAIN_02364 5.1e-46 ypuD
HHGCEAIN_02365 3.6e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HHGCEAIN_02366 8.5e-79 ccdC1 O Protein of unknown function (DUF1453)
HHGCEAIN_02367 5.7e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHGCEAIN_02368 2.6e-150 ypuA S Secreted protein
HHGCEAIN_02369 1.9e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHGCEAIN_02370 9.5e-267 spoVAF EG Stage V sporulation protein AF
HHGCEAIN_02371 2.4e-107 spoVAEA S stage V sporulation protein
HHGCEAIN_02372 2.5e-56 spoVAEB S stage V sporulation protein
HHGCEAIN_02373 3.5e-188 spoVAD I Stage V sporulation protein AD
HHGCEAIN_02374 1.3e-78 spoVAC S stage V sporulation protein AC
HHGCEAIN_02375 1.5e-109 spoVAA S Stage V sporulation protein AA
HHGCEAIN_02376 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHGCEAIN_02377 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HHGCEAIN_02378 2.3e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HHGCEAIN_02379 5.9e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HHGCEAIN_02380 4.2e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HHGCEAIN_02381 2.7e-227 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHGCEAIN_02382 2.7e-163 xerD L recombinase XerD
HHGCEAIN_02383 6.4e-37 S Protein of unknown function (DUF4227)
HHGCEAIN_02384 2.7e-79 fur P Belongs to the Fur family
HHGCEAIN_02385 2.7e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HHGCEAIN_02386 8.1e-32 yqkK
HHGCEAIN_02387 3e-23
HHGCEAIN_02388 3.6e-241 mleA 1.1.1.38 C malic enzyme
HHGCEAIN_02389 1.9e-240 mleN C Na H antiporter
HHGCEAIN_02390 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HHGCEAIN_02391 1.2e-183 ansA 3.5.1.1 EJ L-asparaginase
HHGCEAIN_02392 5e-57 ansR K Transcriptional regulator
HHGCEAIN_02393 2.5e-214 yqxK 3.6.4.12 L DNA helicase
HHGCEAIN_02394 9e-93 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HHGCEAIN_02396 1.2e-163 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HHGCEAIN_02398 1.2e-132 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HHGCEAIN_02399 3.2e-39 yqkC S Protein of unknown function (DUF2552)
HHGCEAIN_02400 1.6e-58 yqkB S Belongs to the HesB IscA family
HHGCEAIN_02401 1.4e-165 yqkA K GrpB protein
HHGCEAIN_02403 2.8e-87 yqjY K acetyltransferase
HHGCEAIN_02404 6.3e-232 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHGCEAIN_02405 9.3e-56 S YolD-like protein
HHGCEAIN_02407 3.3e-144 yueF S transporter activity
HHGCEAIN_02409 5e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HHGCEAIN_02410 1.1e-242 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HHGCEAIN_02411 1.8e-136 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHGCEAIN_02412 2.3e-168 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HHGCEAIN_02413 7.9e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHGCEAIN_02414 1.8e-156 K LysR substrate binding domain
HHGCEAIN_02415 1.6e-46 S GlpM protein
HHGCEAIN_02416 3.9e-94 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HHGCEAIN_02417 8.8e-50 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HHGCEAIN_02418 4.5e-143 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HHGCEAIN_02419 4e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHGCEAIN_02420 2.8e-168 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHGCEAIN_02421 7.7e-285 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHGCEAIN_02422 1.3e-265 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHGCEAIN_02423 9.4e-231 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHGCEAIN_02424 7.4e-27 yqzJ
HHGCEAIN_02425 2.1e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHGCEAIN_02426 5.8e-200 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HHGCEAIN_02427 2e-283 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HHGCEAIN_02428 2e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HHGCEAIN_02430 3.6e-91 yqjB S protein conserved in bacteria
HHGCEAIN_02431 7.7e-169 yqjA S Putative aromatic acid exporter C-terminal domain
HHGCEAIN_02432 1.2e-124 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HHGCEAIN_02433 5.4e-105 artQ E COG0765 ABC-type amino acid transport system, permease component
HHGCEAIN_02434 4.2e-133 artP ET Belongs to the bacterial solute-binding protein 3 family
HHGCEAIN_02435 1e-75 yqiW S Belongs to the UPF0403 family
HHGCEAIN_02436 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HHGCEAIN_02437 3.5e-193 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHGCEAIN_02438 6.7e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHGCEAIN_02439 7.8e-164 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHGCEAIN_02440 5.7e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HHGCEAIN_02441 2e-205 buk 2.7.2.7 C Belongs to the acetokinase family
HHGCEAIN_02442 2.6e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HHGCEAIN_02443 1.3e-149 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HHGCEAIN_02444 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HHGCEAIN_02445 2.7e-33 yqzF S Protein of unknown function (DUF2627)
HHGCEAIN_02446 7.1e-156 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HHGCEAIN_02447 2.3e-265 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HHGCEAIN_02448 3.5e-205 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HHGCEAIN_02449 5.3e-201 mmgC I acyl-CoA dehydrogenase
HHGCEAIN_02450 9.1e-46 hbdA 1.1.1.157 I Dehydrogenase
HHGCEAIN_02451 2.9e-78 hbdA 1.1.1.157 I Dehydrogenase
HHGCEAIN_02452 3.2e-209 mmgA 2.3.1.9 I Belongs to the thiolase family
HHGCEAIN_02453 9.6e-127 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HHGCEAIN_02454 1.4e-97 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HHGCEAIN_02455 5.7e-17
HHGCEAIN_02456 2.3e-92 ytaF P Probably functions as a manganese efflux pump
HHGCEAIN_02457 3.7e-111 K Protein of unknown function (DUF1232)
HHGCEAIN_02459 5.8e-208 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HHGCEAIN_02462 7e-204 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHGCEAIN_02463 2.7e-143 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HHGCEAIN_02464 3.5e-233 rseP 3.4.21.116 M Stage IV sporulation protein B
HHGCEAIN_02465 6.2e-310 recN L May be involved in recombinational repair of damaged DNA
HHGCEAIN_02466 4.3e-77 argR K Regulates arginine biosynthesis genes
HHGCEAIN_02467 9.9e-152 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HHGCEAIN_02468 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHGCEAIN_02469 7e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHGCEAIN_02470 1.3e-38 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHGCEAIN_02471 2.5e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHGCEAIN_02472 5.7e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHGCEAIN_02473 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHGCEAIN_02474 1.4e-66 yqhY S protein conserved in bacteria
HHGCEAIN_02475 8.4e-254 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HHGCEAIN_02476 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHGCEAIN_02477 1.3e-58 spoIIIAH S SpoIIIAH-like protein
HHGCEAIN_02478 1.4e-114 spoIIIAG S stage III sporulation protein AG
HHGCEAIN_02479 1e-100 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HHGCEAIN_02480 4.1e-199 spoIIIAE S stage III sporulation protein AE
HHGCEAIN_02481 3.3e-41 spoIIIAD S Stage III sporulation protein AD
HHGCEAIN_02482 7.6e-29 spoIIIAC S stage III sporulation protein AC
HHGCEAIN_02483 1e-82 spoIIIAB S Stage III sporulation protein
HHGCEAIN_02484 1.7e-165 spoIIIAA S stage III sporulation protein AA
HHGCEAIN_02485 6.7e-36 yqhV S Protein of unknown function (DUF2619)
HHGCEAIN_02486 2.1e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHGCEAIN_02487 5.9e-170 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HHGCEAIN_02488 1.1e-84 yqhR S Conserved membrane protein YqhR
HHGCEAIN_02489 9.1e-170 yqhQ S Protein of unknown function (DUF1385)
HHGCEAIN_02490 1.2e-59 yqhP
HHGCEAIN_02491 5.1e-159 yqhO S esterase of the alpha-beta hydrolase superfamily
HHGCEAIN_02492 4.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HHGCEAIN_02493 4.1e-158 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HHGCEAIN_02494 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
HHGCEAIN_02495 3.6e-282 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HHGCEAIN_02496 1.2e-247 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HHGCEAIN_02497 5.7e-200 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HHGCEAIN_02498 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HHGCEAIN_02499 3e-150 yqhG S Bacterial protein YqhG of unknown function
HHGCEAIN_02500 1.7e-21 sinI S Anti-repressor SinI
HHGCEAIN_02501 3.9e-54 sinR K transcriptional
HHGCEAIN_02502 1.5e-138 tasA S Cell division protein FtsN
HHGCEAIN_02503 5.2e-67 sipW 3.4.21.89 U Signal peptidase
HHGCEAIN_02504 3.6e-112 yqxM
HHGCEAIN_02505 1.1e-53 yqzG S Protein of unknown function (DUF3889)
HHGCEAIN_02506 1.5e-25 yqzE S YqzE-like protein
HHGCEAIN_02507 5.4e-57 S ComG operon protein 7
HHGCEAIN_02508 4.1e-21 comGF U Putative Competence protein ComGF
HHGCEAIN_02509 1.2e-20 comGE
HHGCEAIN_02510 6.4e-70 gspH NU Tfp pilus assembly protein FimT
HHGCEAIN_02511 1.3e-48 comGC U Required for transformation and DNA binding
HHGCEAIN_02512 4e-179 comGB NU COG1459 Type II secretory pathway, component PulF
HHGCEAIN_02513 8.9e-198 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHGCEAIN_02514 6.7e-181 corA P Mg2 transporter protein
HHGCEAIN_02515 1.5e-231 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HHGCEAIN_02516 3e-137 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HHGCEAIN_02518 1.9e-62 yqgZ 1.20.4.1 P Belongs to the ArsC family
HHGCEAIN_02519 3.1e-37 yqgY S Protein of unknown function (DUF2626)
HHGCEAIN_02520 3.6e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HHGCEAIN_02521 5.4e-20 yqgW S Protein of unknown function (DUF2759)
HHGCEAIN_02522 1.7e-48 yqgV S Thiamine-binding protein
HHGCEAIN_02523 2.3e-187 yqgU
HHGCEAIN_02524 5.3e-201 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HHGCEAIN_02525 1.8e-178 glcK 2.7.1.2 G Glucokinase
HHGCEAIN_02526 1.6e-27 yqgQ S Protein conserved in bacteria
HHGCEAIN_02527 4.8e-203 nhaC C Na H antiporter
HHGCEAIN_02528 4e-07 yqgO
HHGCEAIN_02529 5.1e-88 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHGCEAIN_02530 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHGCEAIN_02531 1.2e-50 yqzD
HHGCEAIN_02532 1.3e-73 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHGCEAIN_02533 6.4e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHGCEAIN_02534 2.2e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHGCEAIN_02535 8.5e-154 pstA P Phosphate transport system permease
HHGCEAIN_02536 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
HHGCEAIN_02537 2.3e-154 pstS P Phosphate
HHGCEAIN_02538 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HHGCEAIN_02539 3.3e-223 yqgE EGP Major facilitator superfamily
HHGCEAIN_02540 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HHGCEAIN_02541 4.2e-70 yqgC S protein conserved in bacteria
HHGCEAIN_02542 2.4e-128 yqgB S Protein of unknown function (DUF1189)
HHGCEAIN_02543 4.2e-44 yqfZ M LysM domain
HHGCEAIN_02544 5e-199 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HHGCEAIN_02545 6.7e-52 yqfX S membrane
HHGCEAIN_02546 6.7e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HHGCEAIN_02547 2.4e-71 zur P Belongs to the Fur family
HHGCEAIN_02548 1.1e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HHGCEAIN_02549 7.9e-36 yqfT S Protein of unknown function (DUF2624)
HHGCEAIN_02550 2.9e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HHGCEAIN_02551 5.7e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHGCEAIN_02552 1.6e-25 yqfQ S YqfQ-like protein
HHGCEAIN_02553 1.9e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HHGCEAIN_02554 1.8e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHGCEAIN_02555 1.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
HHGCEAIN_02556 1.3e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
HHGCEAIN_02557 3.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHGCEAIN_02558 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHGCEAIN_02559 8.7e-87 yaiI S Belongs to the UPF0178 family
HHGCEAIN_02560 1.4e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HHGCEAIN_02561 1.3e-111 ccpN K CBS domain
HHGCEAIN_02562 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HHGCEAIN_02563 3.7e-173 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HHGCEAIN_02564 3e-139 recO L Involved in DNA repair and RecF pathway recombination
HHGCEAIN_02565 1.8e-16 S YqzL-like protein
HHGCEAIN_02566 5.2e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHGCEAIN_02567 2.7e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HHGCEAIN_02568 8.6e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HHGCEAIN_02569 9.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHGCEAIN_02570 0.0 yqfF S membrane-associated HD superfamily hydrolase
HHGCEAIN_02571 2.1e-174 phoH T Phosphate starvation-inducible protein PhoH
HHGCEAIN_02572 1.1e-207 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HHGCEAIN_02573 9.3e-46 yqfC S sporulation protein YqfC
HHGCEAIN_02574 4.5e-23 yqfB
HHGCEAIN_02575 5.3e-120 yqfA S UPF0365 protein
HHGCEAIN_02576 6.1e-225 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HHGCEAIN_02577 1.2e-68 yqeY S Yqey-like protein
HHGCEAIN_02578 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HHGCEAIN_02579 1.7e-152 yqeW P COG1283 Na phosphate symporter
HHGCEAIN_02580 1.5e-258 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HHGCEAIN_02581 2.8e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HHGCEAIN_02582 6.6e-173 prmA J Methylates ribosomal protein L11
HHGCEAIN_02583 3.9e-196 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHGCEAIN_02584 0.0 dnaK O Heat shock 70 kDa protein
HHGCEAIN_02585 8.9e-72 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHGCEAIN_02586 5.2e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHGCEAIN_02587 2.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
HHGCEAIN_02588 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHGCEAIN_02589 3.8e-54 yqxA S Protein of unknown function (DUF3679)
HHGCEAIN_02590 2.4e-220 spoIIP M stage II sporulation protein P
HHGCEAIN_02591 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHGCEAIN_02592 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
HHGCEAIN_02593 2.7e-180 holA 2.7.7.7 L DNA polymerase III delta subunit
HHGCEAIN_02594 0.0 comEC S Competence protein ComEC
HHGCEAIN_02595 8e-105 comEB 3.5.4.12 F ComE operon protein 2
HHGCEAIN_02596 7.3e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HHGCEAIN_02597 4.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHGCEAIN_02598 3.2e-138 yqeM Q Methyltransferase
HHGCEAIN_02599 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHGCEAIN_02600 1.8e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HHGCEAIN_02601 9.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHGCEAIN_02602 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HHGCEAIN_02603 1.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HHGCEAIN_02604 3.8e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HHGCEAIN_02605 2e-94 yqeG S hydrolase of the HAD superfamily
HHGCEAIN_02607 4.1e-138 yqeF E GDSL-like Lipase/Acylhydrolase
HHGCEAIN_02608 8.4e-139 3.5.1.104 G Polysaccharide deacetylase
HHGCEAIN_02609 3.6e-106 yqeD S SNARE associated Golgi protein
HHGCEAIN_02610 3.2e-10 2.3.1.57 K Acetyltransferase (GNAT) domain
HHGCEAIN_02612 1.4e-215 EGP Major facilitator Superfamily
HHGCEAIN_02613 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHGCEAIN_02614 1.6e-14 cisA2 L Recombinase
HHGCEAIN_02615 8.1e-151 smc L AAA ATPase domain
HHGCEAIN_02616 1e-40 IQ Enoyl-(Acyl carrier protein) reductase
HHGCEAIN_02617 3.8e-07 Q non-ribosomal peptide synthetase
HHGCEAIN_02619 4.5e-160 efpA EGP Major facilitator superfamily
HHGCEAIN_02620 4.3e-77 pabA 2.6.1.85, 4.1.3.27 EH TIGRFAM glutamine amidotransferase of anthranilate synthase
HHGCEAIN_02621 5.8e-181 trpE 4.1.3.27 EH Anthranilate synthase component I domain protein
HHGCEAIN_02622 2e-175 6.2.1.30 H phenylacetate-CoA ligase activity
HHGCEAIN_02623 0.0 Q AMP-binding enzyme C-terminal domain
HHGCEAIN_02624 7.2e-124 S Winged helix DNA-binding domain
HHGCEAIN_02625 6.1e-204 glyA_1 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHGCEAIN_02626 3.3e-114 mchB Q Thioesterase involved in non-ribosomal peptide biosynthesis
HHGCEAIN_02628 4.1e-162 yobV9 K HTH domain
HHGCEAIN_02629 3.1e-105 yoaZ S DJ-1/PfpI family
HHGCEAIN_02630 5.7e-19
HHGCEAIN_02634 1.7e-20 S SMI1-KNR4 cell-wall
HHGCEAIN_02635 1e-13 xkdS S Protein of unknown function (DUF2634)
HHGCEAIN_02636 2.9e-109 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HHGCEAIN_02637 1.1e-137 yvgN 1.1.1.346 S Reductase
HHGCEAIN_02638 3.2e-69 K MerR family transcriptional regulator
HHGCEAIN_02639 5.7e-16 xkdG S Phage capsid family
HHGCEAIN_02640 5.4e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HHGCEAIN_02641 2.3e-60 K Transcriptional regulator PadR-like family
HHGCEAIN_02642 1e-36 ydeE K AraC family transcriptional regulator
HHGCEAIN_02644 4.4e-97 adk 2.7.4.3 F adenylate kinase activity
HHGCEAIN_02645 2.8e-220 tetL EGP Major facilitator Superfamily
HHGCEAIN_02646 3.3e-81 yyaR K Acetyltransferase (GNAT) domain
HHGCEAIN_02647 4.4e-91 yrdA S DinB family
HHGCEAIN_02649 8.5e-145 S hydrolase
HHGCEAIN_02650 1.7e-72 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HHGCEAIN_02651 1.2e-51 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HHGCEAIN_02652 7.8e-129 glvR K Helix-turn-helix domain, rpiR family
HHGCEAIN_02653 5.8e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
HHGCEAIN_02654 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HHGCEAIN_02655 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HHGCEAIN_02656 1.3e-179 romA S Beta-lactamase superfamily domain
HHGCEAIN_02657 8.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHGCEAIN_02658 4.1e-164 yybE K Transcriptional regulator
HHGCEAIN_02659 3.8e-213 ynfM EGP Major facilitator Superfamily
HHGCEAIN_02660 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HHGCEAIN_02661 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HHGCEAIN_02662 1.5e-92 yrhH Q methyltransferase
HHGCEAIN_02664 8.8e-142 focA P Formate nitrite
HHGCEAIN_02665 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
HHGCEAIN_02666 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HHGCEAIN_02667 7e-81 yrhD S Protein of unknown function (DUF1641)
HHGCEAIN_02668 1.3e-34 yrhC S YrhC-like protein
HHGCEAIN_02669 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HHGCEAIN_02670 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HHGCEAIN_02671 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHGCEAIN_02672 7.1e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HHGCEAIN_02673 4.1e-27 yrzA S Protein of unknown function (DUF2536)
HHGCEAIN_02674 2.6e-68 yrrS S Protein of unknown function (DUF1510)
HHGCEAIN_02675 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HHGCEAIN_02676 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHGCEAIN_02677 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HHGCEAIN_02678 1.6e-246 yegQ O COG0826 Collagenase and related proteases
HHGCEAIN_02679 2.9e-173 yegQ O Peptidase U32
HHGCEAIN_02680 4e-116 yrrM 2.1.1.104 S O-methyltransferase
HHGCEAIN_02681 6.9e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHGCEAIN_02682 7.1e-46 yrzB S Belongs to the UPF0473 family
HHGCEAIN_02683 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHGCEAIN_02684 1.7e-41 yrzL S Belongs to the UPF0297 family
HHGCEAIN_02685 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHGCEAIN_02686 2.1e-159 yrrI S AI-2E family transporter
HHGCEAIN_02687 2.5e-127 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HHGCEAIN_02688 4.4e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
HHGCEAIN_02689 2.2e-106 gluC P ABC transporter
HHGCEAIN_02690 6e-104 glnP P ABC transporter
HHGCEAIN_02691 2.1e-08 S Protein of unknown function (DUF3918)
HHGCEAIN_02692 2.9e-30 yrzR
HHGCEAIN_02693 2.3e-78 yrrD S protein conserved in bacteria
HHGCEAIN_02694 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHGCEAIN_02695 1.7e-18 S COG0457 FOG TPR repeat
HHGCEAIN_02696 5e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHGCEAIN_02697 7e-209 iscS 2.8.1.7 E Cysteine desulfurase
HHGCEAIN_02698 2.9e-63 cymR K Transcriptional regulator
HHGCEAIN_02699 7e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HHGCEAIN_02700 3.3e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HHGCEAIN_02701 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HHGCEAIN_02702 4.5e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
HHGCEAIN_02705 4.2e-265 lytH 3.5.1.28 M COG3103 SH3 domain protein
HHGCEAIN_02706 2e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHGCEAIN_02707 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHGCEAIN_02708 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHGCEAIN_02709 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HHGCEAIN_02710 2.7e-44 yrvD S Lipopolysaccharide assembly protein A domain
HHGCEAIN_02711 4.6e-80 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HHGCEAIN_02712 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHGCEAIN_02713 8e-48 yrzD S Post-transcriptional regulator
HHGCEAIN_02714 9.1e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHGCEAIN_02715 5.1e-103 yrbG S membrane
HHGCEAIN_02716 5.3e-60 yrzE S Protein of unknown function (DUF3792)
HHGCEAIN_02717 2.5e-37 yajC U Preprotein translocase subunit YajC
HHGCEAIN_02718 7.5e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HHGCEAIN_02719 2.7e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HHGCEAIN_02720 2.8e-20 yrzS S Protein of unknown function (DUF2905)
HHGCEAIN_02721 2.9e-182 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHGCEAIN_02722 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHGCEAIN_02723 5.9e-91 bofC S BofC C-terminal domain
HHGCEAIN_02725 4e-26 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHGCEAIN_02726 2.1e-112 safA M spore coat assembly protein SafA
HHGCEAIN_02727 5.4e-206 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HHGCEAIN_02728 1e-140 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HHGCEAIN_02729 1.3e-277 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HHGCEAIN_02730 3.4e-211 nifS 2.8.1.7 E Cysteine desulfurase
HHGCEAIN_02731 2.9e-88 niaR S small molecule binding protein (contains 3H domain)
HHGCEAIN_02732 6.1e-157 pheA 4.2.1.51 E Prephenate dehydratase
HHGCEAIN_02733 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HHGCEAIN_02734 6.4e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHGCEAIN_02735 4.8e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HHGCEAIN_02736 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HHGCEAIN_02737 7e-56 ysxB J ribosomal protein
HHGCEAIN_02738 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HHGCEAIN_02739 2.3e-156 spoIVFB S Stage IV sporulation protein
HHGCEAIN_02740 3.8e-137 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HHGCEAIN_02741 2.3e-142 minD D Belongs to the ParA family
HHGCEAIN_02742 2.2e-101 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HHGCEAIN_02743 1.1e-81 mreD M shape-determining protein
HHGCEAIN_02744 8e-157 mreC M Involved in formation and maintenance of cell shape
HHGCEAIN_02745 1.3e-182 mreB D Rod shape-determining protein MreB
HHGCEAIN_02746 4.5e-126 radC E Belongs to the UPF0758 family
HHGCEAIN_02747 3.8e-99 maf D septum formation protein Maf
HHGCEAIN_02748 2.5e-125 spoIIB S Sporulation related domain
HHGCEAIN_02749 4.6e-124 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HHGCEAIN_02750 1.2e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HHGCEAIN_02751 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHGCEAIN_02752 3.1e-24
HHGCEAIN_02753 4.9e-185 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HHGCEAIN_02754 5.7e-150 spoVID M stage VI sporulation protein D
HHGCEAIN_02755 7.1e-242 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HHGCEAIN_02756 2.1e-182 hemB 4.2.1.24 H Belongs to the ALAD family
HHGCEAIN_02757 1.1e-136 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HHGCEAIN_02758 1.8e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HHGCEAIN_02759 3.6e-146 hemX O cytochrome C
HHGCEAIN_02760 2.1e-244 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HHGCEAIN_02761 5.1e-84 ysxD
HHGCEAIN_02762 1.5e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HHGCEAIN_02763 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HHGCEAIN_02764 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HHGCEAIN_02765 1.9e-228 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHGCEAIN_02766 1.3e-211 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHGCEAIN_02767 1e-187 ysoA H Tetratricopeptide repeat
HHGCEAIN_02768 1.3e-113 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHGCEAIN_02769 2.5e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHGCEAIN_02770 6.5e-196 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HHGCEAIN_02771 9e-284 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HHGCEAIN_02772 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HHGCEAIN_02773 3.5e-83 ilvN 2.2.1.6 E Acetolactate synthase
HHGCEAIN_02774 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HHGCEAIN_02779 6.1e-88 ysnB S Phosphoesterase
HHGCEAIN_02780 8e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHGCEAIN_02781 5.8e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HHGCEAIN_02782 3.4e-197 gerM S COG5401 Spore germination protein
HHGCEAIN_02783 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HHGCEAIN_02784 4.1e-72 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HHGCEAIN_02785 2e-30 gerE K Transcriptional regulator
HHGCEAIN_02786 2.1e-73 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HHGCEAIN_02787 3.9e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HHGCEAIN_02788 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HHGCEAIN_02789 4.8e-108 sdhC C succinate dehydrogenase
HHGCEAIN_02790 3.5e-79 yslB S Protein of unknown function (DUF2507)
HHGCEAIN_02791 1.2e-211 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HHGCEAIN_02792 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHGCEAIN_02793 2.5e-52 trxA O Belongs to the thioredoxin family
HHGCEAIN_02794 8.9e-297 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HHGCEAIN_02795 1.1e-175 etfA C Electron transfer flavoprotein
HHGCEAIN_02796 2.2e-137 etfB C Electron transfer flavoprotein
HHGCEAIN_02797 3.6e-132 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HHGCEAIN_02798 2.7e-103 fadR K Transcriptional regulator
HHGCEAIN_02799 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHGCEAIN_02800 2e-115 ywbB S Protein of unknown function (DUF2711)
HHGCEAIN_02801 4.7e-67 yshE S membrane
HHGCEAIN_02802 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHGCEAIN_02803 0.0 polX L COG1796 DNA polymerase IV (family X)
HHGCEAIN_02804 2.3e-82 cvpA S membrane protein, required for colicin V production
HHGCEAIN_02805 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HHGCEAIN_02806 1.5e-164 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHGCEAIN_02807 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHGCEAIN_02808 4e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHGCEAIN_02809 1e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHGCEAIN_02810 7.6e-32 sspI S Belongs to the SspI family
HHGCEAIN_02811 8.2e-191 ysfB KT regulator
HHGCEAIN_02812 2.8e-252 glcD 1.1.3.15 C FAD binding domain
HHGCEAIN_02813 4.1e-245 glcF C Glycolate oxidase
HHGCEAIN_02814 0.0 cstA T Carbon starvation protein
HHGCEAIN_02815 1.7e-295 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HHGCEAIN_02816 5.1e-140 araQ G transport system permease
HHGCEAIN_02817 9.6e-164 araP P PFAM binding-protein-dependent transport systems inner membrane component
HHGCEAIN_02818 6.2e-246 araN G carbohydrate transport
HHGCEAIN_02819 7e-212 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HHGCEAIN_02820 4e-137 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HHGCEAIN_02821 1.6e-131 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HHGCEAIN_02822 2.8e-307 araB 2.7.1.16 C Belongs to the ribulokinase family
HHGCEAIN_02823 1.5e-291 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HHGCEAIN_02824 1e-184 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HHGCEAIN_02825 4e-206 ysdC G COG1363 Cellulase M and related proteins
HHGCEAIN_02826 2.6e-62 ysdB S Sigma-w pathway protein YsdB
HHGCEAIN_02827 1e-38 ysdA S Membrane
HHGCEAIN_02828 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHGCEAIN_02829 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HHGCEAIN_02830 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHGCEAIN_02831 2.7e-107 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HHGCEAIN_02832 3.6e-36 lrgA S effector of murein hydrolase LrgA
HHGCEAIN_02833 1e-128 lytT T COG3279 Response regulator of the LytR AlgR family
HHGCEAIN_02834 0.0 lytS 2.7.13.3 T Histidine kinase
HHGCEAIN_02835 4.1e-147 ysaA S HAD-hyrolase-like
HHGCEAIN_02836 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHGCEAIN_02837 1.6e-149 ytxC S YtxC-like family
HHGCEAIN_02838 4e-105 ytxB S SNARE associated Golgi protein
HHGCEAIN_02839 2.9e-168 dnaI L Primosomal protein DnaI
HHGCEAIN_02840 7.7e-250 dnaB L Membrane attachment protein
HHGCEAIN_02841 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHGCEAIN_02842 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HHGCEAIN_02843 1.3e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHGCEAIN_02844 1.6e-64 ytcD K Transcriptional regulator
HHGCEAIN_02845 6.9e-199 ytbD EGP Major facilitator Superfamily
HHGCEAIN_02846 1.5e-155 ytbE S reductase
HHGCEAIN_02847 3.9e-94 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHGCEAIN_02848 2.6e-104 ytaF P Probably functions as a manganese efflux pump
HHGCEAIN_02849 2.7e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHGCEAIN_02850 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHGCEAIN_02851 7.7e-308 phoR 2.7.13.3 T Signal transduction histidine kinase
HHGCEAIN_02852 5e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHGCEAIN_02853 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HHGCEAIN_02854 2e-241 icd 1.1.1.42 C isocitrate
HHGCEAIN_02855 8.1e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HHGCEAIN_02856 1.5e-72 yeaL S membrane
HHGCEAIN_02857 1.8e-193 ytvI S sporulation integral membrane protein YtvI
HHGCEAIN_02858 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HHGCEAIN_02859 1.2e-292 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HHGCEAIN_02860 9.8e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHGCEAIN_02861 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HHGCEAIN_02862 6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHGCEAIN_02863 5.9e-222 ytsJ 1.1.1.38 C Malate dehydrogenase
HHGCEAIN_02864 0.0 dnaE 2.7.7.7 L DNA polymerase
HHGCEAIN_02865 3.9e-54 ytrH S Sporulation protein YtrH
HHGCEAIN_02866 5.6e-86 ytrI
HHGCEAIN_02867 6.4e-22
HHGCEAIN_02868 2.9e-176 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HHGCEAIN_02869 3.8e-45 ytpI S YtpI-like protein
HHGCEAIN_02870 6.8e-238 ytoI K transcriptional regulator containing CBS domains
HHGCEAIN_02871 1.1e-127 ytkL S Belongs to the UPF0173 family
HHGCEAIN_02872 3.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHGCEAIN_02874 6.1e-260 argH 4.3.2.1 E argininosuccinate lyase
HHGCEAIN_02875 4.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HHGCEAIN_02876 8e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HHGCEAIN_02877 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHGCEAIN_02878 9.7e-175 ytxK 2.1.1.72 L DNA methylase
HHGCEAIN_02879 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHGCEAIN_02880 1.5e-63 ytfJ S Sporulation protein YtfJ
HHGCEAIN_02881 4.1e-111 ytfI S Protein of unknown function (DUF2953)
HHGCEAIN_02882 4.5e-80 yteJ S RDD family
HHGCEAIN_02883 1.4e-176 sppA OU signal peptide peptidase SppA
HHGCEAIN_02884 5.9e-149 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHGCEAIN_02885 8.3e-301 ytcJ S amidohydrolase
HHGCEAIN_02886 9.1e-300 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HHGCEAIN_02887 6.6e-31 sspB S spore protein
HHGCEAIN_02888 1.4e-220 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHGCEAIN_02889 3.4e-203 iscS2 2.8.1.7 E Cysteine desulfurase
HHGCEAIN_02890 6.4e-238 braB E Component of the transport system for branched-chain amino acids
HHGCEAIN_02891 2.3e-261 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHGCEAIN_02892 4.3e-144 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HHGCEAIN_02893 7.9e-106 yttP K Transcriptional regulator
HHGCEAIN_02894 8.6e-84 ytsP 1.8.4.14 T GAF domain-containing protein
HHGCEAIN_02895 4.6e-268 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HHGCEAIN_02896 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHGCEAIN_02897 2.2e-213 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHGCEAIN_02900 1.3e-08 yhbO 1.11.1.6, 3.5.1.124 S protease
HHGCEAIN_02902 2.9e-126 E GDSL-like Lipase/Acylhydrolase family
HHGCEAIN_02903 5.8e-147 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHGCEAIN_02904 5.4e-147 K Transcriptional regulator
HHGCEAIN_02905 1.9e-119 azlC E AzlC protein
HHGCEAIN_02906 7.4e-47 azlD S Branched-chain amino acid transport protein (AzlD)
HHGCEAIN_02907 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHGCEAIN_02908 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HHGCEAIN_02909 7.5e-120 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HHGCEAIN_02910 2e-107 acuB S Domain in cystathionine beta-synthase and other proteins.
HHGCEAIN_02911 7.9e-224 acuC BQ histone deacetylase
HHGCEAIN_02912 2.7e-98 motS N Flagellar motor protein
HHGCEAIN_02913 4.8e-143 motA N flagellar motor
HHGCEAIN_02914 3.9e-179 ccpA K catabolite control protein A
HHGCEAIN_02915 1.6e-194 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HHGCEAIN_02916 2.2e-43 ytxJ O Protein of unknown function (DUF2847)
HHGCEAIN_02917 1.7e-16 ytxH S COG4980 Gas vesicle protein
HHGCEAIN_02918 8.2e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHGCEAIN_02919 7.1e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HHGCEAIN_02920 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HHGCEAIN_02921 5.9e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHGCEAIN_02922 3e-145 ytpQ S Belongs to the UPF0354 family
HHGCEAIN_02923 3.5e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HHGCEAIN_02924 1.8e-75 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HHGCEAIN_02925 4.1e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HHGCEAIN_02926 1.7e-51 ytzB S small secreted protein
HHGCEAIN_02927 4.2e-228 sfcA 1.1.1.38 C Malate dehydrogenase
HHGCEAIN_02928 4.9e-73 sfcA 1.1.1.38 C Malate dehydrogenase
HHGCEAIN_02929 3.4e-160 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HHGCEAIN_02930 1.5e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHGCEAIN_02931 1.3e-44 ytzH S YtzH-like protein
HHGCEAIN_02932 4.1e-155 ytmP 2.7.1.89 M Phosphotransferase
HHGCEAIN_02933 2.6e-169 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HHGCEAIN_02934 5.1e-141 ytlQ
HHGCEAIN_02935 2.4e-98 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HHGCEAIN_02936 1.6e-166 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HHGCEAIN_02937 6.2e-260 pepV 3.5.1.18 E Dipeptidase
HHGCEAIN_02938 5.5e-226 pbuO S permease
HHGCEAIN_02939 2.5e-198 ythQ U Bacterial ABC transporter protein EcsB
HHGCEAIN_02940 1.9e-116 ythP V ABC transporter
HHGCEAIN_02941 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HHGCEAIN_02942 2e-124 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHGCEAIN_02943 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHGCEAIN_02944 5.5e-231 ytfP S HI0933-like protein
HHGCEAIN_02945 1.4e-276 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HHGCEAIN_02946 2.6e-25 yteV S Sporulation protein Cse60
HHGCEAIN_02947 2.1e-120 msmR K Transcriptional regulator
HHGCEAIN_02948 4.1e-234 msmE G Bacterial extracellular solute-binding protein
HHGCEAIN_02949 5.5e-164 amyD G Binding-protein-dependent transport system inner membrane component
HHGCEAIN_02950 1.5e-141 amyC P ABC transporter (permease)
HHGCEAIN_02951 8.1e-246 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HHGCEAIN_02952 1.1e-73 M Acetyltransferase (GNAT) domain
HHGCEAIN_02953 1.3e-51 ytwF P Sulfurtransferase
HHGCEAIN_02954 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHGCEAIN_02955 1.2e-52 ytvB S Protein of unknown function (DUF4257)
HHGCEAIN_02956 3.5e-135 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HHGCEAIN_02957 4.9e-205 yttB EGP Major facilitator Superfamily
HHGCEAIN_02958 4e-102 ywaF S Integral membrane protein
HHGCEAIN_02959 0.0 bceB V ABC transporter (permease)
HHGCEAIN_02960 2.7e-132 bceA V ABC transporter, ATP-binding protein
HHGCEAIN_02961 5.4e-154 T PhoQ Sensor
HHGCEAIN_02962 1.1e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHGCEAIN_02963 5.8e-199 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HHGCEAIN_02964 1.1e-124 ytrE V ABC transporter, ATP-binding protein
HHGCEAIN_02965 1.8e-144
HHGCEAIN_02966 7.8e-148 P ABC-2 family transporter protein
HHGCEAIN_02967 1.6e-127 S ABC-2 family transporter protein
HHGCEAIN_02968 1.4e-156 ytrB P abc transporter atp-binding protein
HHGCEAIN_02969 4.3e-65 ytrA K GntR family transcriptional regulator
HHGCEAIN_02971 8.1e-39 ytzC S Protein of unknown function (DUF2524)
HHGCEAIN_02972 1.4e-189 yhcC S Fe-S oxidoreductase
HHGCEAIN_02973 3.4e-103 ytqB J Putative rRNA methylase
HHGCEAIN_02975 7.3e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HHGCEAIN_02976 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HHGCEAIN_02977 1.8e-55 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HHGCEAIN_02978 8.5e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HHGCEAIN_02979 0.0 asnB 6.3.5.4 E Asparagine synthase
HHGCEAIN_02980 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHGCEAIN_02981 3e-303 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HHGCEAIN_02982 8e-38 ytmB S Protein of unknown function (DUF2584)
HHGCEAIN_02983 2.2e-145 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HHGCEAIN_02984 1.9e-178 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HHGCEAIN_02985 1.5e-141 ytlC P ABC transporter
HHGCEAIN_02986 3.8e-124 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHGCEAIN_02987 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HHGCEAIN_02988 1.2e-59 ytkC S Bacteriophage holin family
HHGCEAIN_02989 7.8e-76 dps P Belongs to the Dps family
HHGCEAIN_02991 6.7e-75 ytkA S YtkA-like
HHGCEAIN_02992 2.2e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHGCEAIN_02993 2e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HHGCEAIN_02994 1.3e-102 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HHGCEAIN_02995 7.9e-41 rpmE2 J Ribosomal protein L31
HHGCEAIN_02996 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
HHGCEAIN_02997 1.9e-181 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HHGCEAIN_02998 4e-24 S Domain of Unknown Function (DUF1540)
HHGCEAIN_02999 2e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HHGCEAIN_03000 1.7e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HHGCEAIN_03001 7.9e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HHGCEAIN_03002 1.9e-147 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HHGCEAIN_03003 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HHGCEAIN_03004 3.7e-260 menF 5.4.4.2 HQ Isochorismate synthase
HHGCEAIN_03005 2.3e-125 dksA T COG1734 DnaK suppressor protein
HHGCEAIN_03006 4.8e-71 tspO T membrane
HHGCEAIN_03015 7.8e-08
HHGCEAIN_03016 1.3e-09
HHGCEAIN_03023 1.6e-08
HHGCEAIN_03030 2.2e-38 S COG NOG14552 non supervised orthologous group
HHGCEAIN_03031 1.8e-91 thiT S Thiamine transporter protein (Thia_YuaJ)
HHGCEAIN_03032 6.1e-176 yuaG 3.4.21.72 S protein conserved in bacteria
HHGCEAIN_03033 2.6e-81 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HHGCEAIN_03034 2.2e-79 yuaE S DinB superfamily
HHGCEAIN_03035 1.2e-103 yuaD S MOSC domain
HHGCEAIN_03036 6.7e-226 gbsB 1.1.1.1 C alcohol dehydrogenase
HHGCEAIN_03037 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HHGCEAIN_03038 3.4e-92 yuaC K Belongs to the GbsR family
HHGCEAIN_03039 4.3e-92 yuaB
HHGCEAIN_03040 1.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
HHGCEAIN_03041 9.3e-142 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHGCEAIN_03042 5.2e-207 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHGCEAIN_03043 1.7e-36 G Cupin
HHGCEAIN_03044 1.1e-42 yjcN
HHGCEAIN_03047 2.4e-132 S Aspartate phosphatase response regulator
HHGCEAIN_03048 4e-14
HHGCEAIN_03053 2.2e-18 K Cro/C1-type HTH DNA-binding domain
HHGCEAIN_03055 6e-40
HHGCEAIN_03056 1.9e-240 I Pfam Lipase (class 3)
HHGCEAIN_03057 1.9e-51 S Protein of unknown function (DUF1433)
HHGCEAIN_03058 9.5e-15 K Helix-turn-helix domain
HHGCEAIN_03060 9.9e-46 M D-alanyl-D-alanine carboxypeptidase
HHGCEAIN_03061 5.6e-44 S Bacteriophage holin family
HHGCEAIN_03063 1.4e-14
HHGCEAIN_03064 2.1e-66 S Domain of unknown function (DUF2479)
HHGCEAIN_03065 2.9e-263 M Pectate lyase superfamily protein
HHGCEAIN_03066 1.1e-105 mur1 NU Prophage endopeptidase tail
HHGCEAIN_03067 2.4e-41 S Phage tail protein
HHGCEAIN_03068 0.0 D Phage tail tape measure protein
HHGCEAIN_03070 4.3e-08
HHGCEAIN_03071 9e-27 S Phage tail tube protein
HHGCEAIN_03072 1.1e-09
HHGCEAIN_03073 3.6e-32 S Bacteriophage HK97-gp10, putative tail-component
HHGCEAIN_03074 1e-19 S Phage head-tail joining protein
HHGCEAIN_03075 4.1e-20 S Phage gp6-like head-tail connector protein
HHGCEAIN_03076 1.6e-102 S capsid protein
HHGCEAIN_03077 6.7e-54 pi136 S Caudovirus prohead serine protease
HHGCEAIN_03078 1.2e-145 S portal protein
HHGCEAIN_03080 3.3e-122 terL S Terminase
HHGCEAIN_03081 1.1e-51 terS L Terminase, small subunit
HHGCEAIN_03086 4.4e-14 S HNH endonuclease
HHGCEAIN_03093 3.8e-54 K BRO family, N-terminal domain
HHGCEAIN_03097 4.1e-61
HHGCEAIN_03098 1.4e-10 K Helix-turn-helix domain
HHGCEAIN_03100 2.8e-72 L Phage integrase family
HHGCEAIN_03102 2.8e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHGCEAIN_03103 5.5e-193 yubA S transporter activity
HHGCEAIN_03104 9.1e-181 ygjR S Oxidoreductase
HHGCEAIN_03105 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HHGCEAIN_03106 5.9e-227 mcpA NT chemotaxis protein
HHGCEAIN_03107 2.2e-218 mcpA NT chemotaxis protein
HHGCEAIN_03108 1.3e-213 mcpA NT chemotaxis protein
HHGCEAIN_03109 5.5e-209 mcpA NT chemotaxis protein
HHGCEAIN_03110 3.3e-135 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HHGCEAIN_03111 5.8e-39
HHGCEAIN_03112 3.6e-186 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HHGCEAIN_03113 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HHGCEAIN_03114 8.1e-230 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HHGCEAIN_03115 4.1e-116 yugP S Zn-dependent protease
HHGCEAIN_03116 6.5e-17
HHGCEAIN_03117 1e-27 mstX S Membrane-integrating protein Mistic
HHGCEAIN_03118 1.6e-177 yugO P COG1226 Kef-type K transport systems
HHGCEAIN_03119 5e-69 yugN S YugN-like family
HHGCEAIN_03121 2.1e-257 pgi 5.3.1.9 G Belongs to the GPI family
HHGCEAIN_03122 5.8e-227 yugK C Dehydrogenase
HHGCEAIN_03123 1e-223 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HHGCEAIN_03124 6.8e-34 yuzA S Domain of unknown function (DUF378)
HHGCEAIN_03125 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HHGCEAIN_03126 3e-207 yugH 2.6.1.1 E Aminotransferase
HHGCEAIN_03127 5.8e-83 alaR K Transcriptional regulator
HHGCEAIN_03128 2e-149 yugF I Hydrolase
HHGCEAIN_03129 5e-38 yugE S Domain of unknown function (DUF1871)
HHGCEAIN_03130 9.9e-219 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HHGCEAIN_03131 2.9e-219 T PhoQ Sensor
HHGCEAIN_03132 7.4e-62 kapB G Kinase associated protein B
HHGCEAIN_03133 6.8e-114 kapD L the KinA pathway to sporulation
HHGCEAIN_03134 1.5e-165 yuxJ EGP Major facilitator Superfamily
HHGCEAIN_03135 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HHGCEAIN_03136 1e-69 yuxK S protein conserved in bacteria
HHGCEAIN_03137 1.1e-71 yufK S Family of unknown function (DUF5366)
HHGCEAIN_03138 4.2e-292 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HHGCEAIN_03139 8.7e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HHGCEAIN_03140 5.1e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HHGCEAIN_03141 1.7e-279 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HHGCEAIN_03142 7.4e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
HHGCEAIN_03143 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
HHGCEAIN_03144 9.8e-11
HHGCEAIN_03145 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HHGCEAIN_03146 6.6e-67 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHGCEAIN_03147 2.2e-49 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHGCEAIN_03148 7.4e-259 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHGCEAIN_03149 5.5e-75 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHGCEAIN_03150 1.4e-36 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHGCEAIN_03151 9.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HHGCEAIN_03152 2.6e-59 ydiI Q protein, possibly involved in aromatic compounds catabolism
HHGCEAIN_03153 1.5e-112 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHGCEAIN_03154 4.2e-253 comP 2.7.13.3 T Histidine kinase
HHGCEAIN_03156 2.9e-61 comQ H Belongs to the FPP GGPP synthase family
HHGCEAIN_03158 1.6e-47 yuzC
HHGCEAIN_03159 8.2e-224 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HHGCEAIN_03160 2.8e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHGCEAIN_03161 3e-101 pncA Q COG1335 Amidases related to nicotinamidase
HHGCEAIN_03162 1.1e-65 yueI S Protein of unknown function (DUF1694)
HHGCEAIN_03163 4.8e-38 yueH S YueH-like protein
HHGCEAIN_03164 7.1e-33 yueG S Spore germination protein gerPA/gerPF
HHGCEAIN_03165 4.1e-182 yueF S transporter activity
HHGCEAIN_03166 1.6e-22 S Protein of unknown function (DUF2642)
HHGCEAIN_03167 2.4e-95 yueE S phosphohydrolase
HHGCEAIN_03168 3.4e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHGCEAIN_03169 2.7e-74 yueC S Family of unknown function (DUF5383)
HHGCEAIN_03170 0.0 esaA S type VII secretion protein EsaA
HHGCEAIN_03171 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HHGCEAIN_03172 6.3e-198 essB S WXG100 protein secretion system (Wss), protein YukC
HHGCEAIN_03173 9.6e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
HHGCEAIN_03174 1.7e-45 esxA S Belongs to the WXG100 family
HHGCEAIN_03175 6.8e-226 yukF QT Transcriptional regulator
HHGCEAIN_03176 1.3e-202 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HHGCEAIN_03177 1.9e-129 yukJ S Uncharacterized conserved protein (DUF2278)
HHGCEAIN_03178 1.7e-31 mbtH S MbtH-like protein
HHGCEAIN_03179 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHGCEAIN_03180 2.3e-162 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HHGCEAIN_03181 3.6e-307 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HHGCEAIN_03182 5.8e-214 entC 5.4.4.2 HQ Isochorismate synthase
HHGCEAIN_03183 2.2e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHGCEAIN_03184 8.9e-156 besA S Putative esterase
HHGCEAIN_03185 3e-118 yuiH S Oxidoreductase molybdopterin binding domain
HHGCEAIN_03186 1.2e-100 bioY S Biotin biosynthesis protein
HHGCEAIN_03187 1.5e-207 yuiF S antiporter
HHGCEAIN_03188 1.2e-277 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HHGCEAIN_03189 6.5e-76 yuiD S protein conserved in bacteria
HHGCEAIN_03190 1.3e-114 yuiC S protein conserved in bacteria
HHGCEAIN_03191 4.9e-27 yuiB S Putative membrane protein
HHGCEAIN_03192 1.1e-233 yumB 1.6.99.3 C NADH dehydrogenase
HHGCEAIN_03193 1.8e-184 yumC 1.18.1.2, 1.19.1.1 C reductase
HHGCEAIN_03195 3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHGCEAIN_03196 2e-27
HHGCEAIN_03197 1.4e-66 CP Membrane
HHGCEAIN_03198 3.5e-118 V ABC transporter
HHGCEAIN_03200 4.2e-28 S Bacteriocin class IId cyclical uberolysin-like
HHGCEAIN_03202 6.6e-42 rimJ 2.3.1.128 J Alanine acetyltransferase
HHGCEAIN_03203 1.3e-129 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HHGCEAIN_03204 2.6e-61 erpA S Belongs to the HesB IscA family
HHGCEAIN_03205 3.8e-159 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HHGCEAIN_03206 3.6e-203 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHGCEAIN_03207 1.9e-36 yuzB S Belongs to the UPF0349 family
HHGCEAIN_03208 5.7e-205 yutJ 1.6.99.3 C NADH dehydrogenase
HHGCEAIN_03209 4.1e-53 yuzD S protein conserved in bacteria
HHGCEAIN_03210 1.6e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HHGCEAIN_03211 3.9e-252 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HHGCEAIN_03212 1.3e-54 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HHGCEAIN_03213 3.1e-162 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHGCEAIN_03214 4.5e-194 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HHGCEAIN_03215 5.1e-240 hom 1.1.1.3 E homoserine dehydrogenase
HHGCEAIN_03216 6.3e-193 yutH S Spore coat protein
HHGCEAIN_03217 5.2e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HHGCEAIN_03218 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHGCEAIN_03219 8.9e-72 yutE S Protein of unknown function DUF86
HHGCEAIN_03220 1.7e-47 yutD S protein conserved in bacteria
HHGCEAIN_03221 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HHGCEAIN_03222 2.5e-191 lytH M Peptidase, M23
HHGCEAIN_03223 1.1e-128 yunB S Sporulation protein YunB (Spo_YunB)
HHGCEAIN_03224 1.2e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HHGCEAIN_03225 4.8e-143 yunE S membrane transporter protein
HHGCEAIN_03226 9.9e-168 yunF S Protein of unknown function DUF72
HHGCEAIN_03227 2.1e-55 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
HHGCEAIN_03228 2.7e-252 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HHGCEAIN_03229 1.7e-293 pucR QT COG2508 Regulator of polyketide synthase expression
HHGCEAIN_03230 2.8e-65
HHGCEAIN_03231 1.4e-207 blt EGP Major facilitator Superfamily
HHGCEAIN_03232 1.2e-225 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HHGCEAIN_03233 6.4e-224 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHGCEAIN_03234 7e-161 bsn L Ribonuclease
HHGCEAIN_03235 7e-198 msmX P Belongs to the ABC transporter superfamily
HHGCEAIN_03236 1.5e-132 yurK K UTRA
HHGCEAIN_03237 2.5e-158 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HHGCEAIN_03238 2.4e-156 yurM P COG0395 ABC-type sugar transport system, permease component
HHGCEAIN_03239 2.2e-157 yurN G Binding-protein-dependent transport system inner membrane component
HHGCEAIN_03240 2.1e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HHGCEAIN_03241 5.3e-181 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HHGCEAIN_03242 8.3e-160 K helix_turn_helix, mercury resistance
HHGCEAIN_03243 1e-14
HHGCEAIN_03244 5.3e-77
HHGCEAIN_03245 2.1e-22 S Sporulation delaying protein SdpA
HHGCEAIN_03247 2.6e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HHGCEAIN_03248 3.5e-197 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HHGCEAIN_03249 3.4e-101 Q ubiE/COQ5 methyltransferase family
HHGCEAIN_03250 1.1e-72 yncE S Protein of unknown function (DUF2691)
HHGCEAIN_03251 1.9e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HHGCEAIN_03252 9.9e-10
HHGCEAIN_03253 5.7e-48
HHGCEAIN_03255 1.3e-70 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HHGCEAIN_03256 6.4e-59 S Pfam:Phage_holin_4_1
HHGCEAIN_03259 7.4e-134 S Domain of unknown function (DUF2479)
HHGCEAIN_03260 0.0 M Pectate lyase superfamily protein
HHGCEAIN_03261 1.4e-261 NU Prophage endopeptidase tail
HHGCEAIN_03262 5.4e-118 S Phage tail protein
HHGCEAIN_03263 0.0 D Phage tail tape measure protein
HHGCEAIN_03265 2.4e-32 S Phage tail tube protein
HHGCEAIN_03266 4.8e-08
HHGCEAIN_03267 1.1e-33 S Bacteriophage HK97-gp10, putative tail-component
HHGCEAIN_03268 4.9e-30 S Phage head-tail joining protein
HHGCEAIN_03269 1.7e-21 S Phage gp6-like head-tail connector protein
HHGCEAIN_03270 2.3e-19
HHGCEAIN_03271 3.3e-124 S capsid protein
HHGCEAIN_03272 1.2e-74 pi136 S Caudovirus prohead serine protease
HHGCEAIN_03273 5.4e-175 S portal protein
HHGCEAIN_03275 8.6e-259 terL S Terminase
HHGCEAIN_03276 7.9e-61 terS L Terminase, small subunit
HHGCEAIN_03278 1.7e-47
HHGCEAIN_03279 7.5e-226 KL SNF2 family N-terminal domain
HHGCEAIN_03280 1.2e-14 S VRR_NUC
HHGCEAIN_03281 0.0 L Virulence-associated protein E
HHGCEAIN_03283 4.4e-296 2.7.7.7 L DNA polymerase A domain
HHGCEAIN_03284 4.3e-23
HHGCEAIN_03285 7.8e-84 S Protein of unknown function (DUF2815)
HHGCEAIN_03286 1.9e-26
HHGCEAIN_03287 1.9e-161 L Protein of unknown function (DUF2800)
HHGCEAIN_03288 9.4e-12
HHGCEAIN_03289 1.6e-43
HHGCEAIN_03291 3.9e-33 S Uncharacterized protein YqaH
HHGCEAIN_03293 8.9e-30
HHGCEAIN_03294 4.9e-19
HHGCEAIN_03295 1.3e-54 K Cro/C1-type HTH DNA-binding domain
HHGCEAIN_03296 2.1e-54 E IrrE N-terminal-like domain
HHGCEAIN_03297 1.1e-150 S Pfam:Arm-DNA-bind_4
HHGCEAIN_03298 8.7e-270 sufB O FeS cluster assembly
HHGCEAIN_03299 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HHGCEAIN_03300 2.8e-232 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHGCEAIN_03301 7e-245 sufD O assembly protein SufD
HHGCEAIN_03302 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HHGCEAIN_03303 6.7e-09
HHGCEAIN_03304 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHGCEAIN_03305 4e-142 metQ P Belongs to the NlpA lipoprotein family
HHGCEAIN_03306 8.3e-93 metI P COG2011 ABC-type metal ion transport system, permease component
HHGCEAIN_03307 1.1e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHGCEAIN_03308 2.1e-55 yusD S SCP-2 sterol transfer family
HHGCEAIN_03309 5.2e-53 yusE CO Thioredoxin
HHGCEAIN_03310 9.7e-22 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HHGCEAIN_03311 2.1e-38 yusG S Protein of unknown function (DUF2553)
HHGCEAIN_03312 5.5e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HHGCEAIN_03313 1.8e-62 arsC 1.20.4.1 P Belongs to the ArsC family
HHGCEAIN_03314 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HHGCEAIN_03315 1e-215 fadA 2.3.1.16 I Belongs to the thiolase family
HHGCEAIN_03316 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HHGCEAIN_03318 3.9e-162 fadM E Proline dehydrogenase
HHGCEAIN_03319 3.5e-39
HHGCEAIN_03320 1.3e-51 yusN M Coat F domain
HHGCEAIN_03321 4.5e-66 yusO K Iron dependent repressor, N-terminal DNA binding domain
HHGCEAIN_03322 5.4e-284 yusP P Major facilitator superfamily
HHGCEAIN_03323 9.8e-59 L PFAM Restriction endonuclease BamHI
HHGCEAIN_03324 1.8e-16 K Helix-turn-helix XRE-family like proteins
HHGCEAIN_03325 2.2e-126 2.1.1.72 L DNA methylase
HHGCEAIN_03326 8.1e-38 yusU S Protein of unknown function (DUF2573)
HHGCEAIN_03327 3.1e-150 yusV 3.6.3.34 HP ABC transporter
HHGCEAIN_03328 1e-46 S YusW-like protein
HHGCEAIN_03329 0.0 pepF2 E COG1164 Oligoendopeptidase F
HHGCEAIN_03330 3.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHGCEAIN_03331 1.5e-77 dps P Belongs to the Dps family
HHGCEAIN_03332 3.5e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHGCEAIN_03333 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHGCEAIN_03334 6.3e-249 cssS 2.7.13.3 T PhoQ Sensor
HHGCEAIN_03335 1.3e-23
HHGCEAIN_03336 3e-154 yuxN K Transcriptional regulator
HHGCEAIN_03337 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHGCEAIN_03338 6.6e-24 S Protein of unknown function (DUF3970)
HHGCEAIN_03339 5.3e-254 gerAA EG Spore germination protein
HHGCEAIN_03340 4.6e-181 gerAB E Spore germination protein
HHGCEAIN_03341 7.6e-192 gerAC S Spore germination B3/ GerAC like, C-terminal
HHGCEAIN_03342 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHGCEAIN_03343 1.1e-192 vraS 2.7.13.3 T Histidine kinase
HHGCEAIN_03344 4.4e-124 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HHGCEAIN_03345 2.1e-117 liaG S Putative adhesin
HHGCEAIN_03346 8.7e-90 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HHGCEAIN_03347 6.9e-44 liaI S membrane
HHGCEAIN_03348 1.2e-220 yvqJ EGP Major facilitator Superfamily
HHGCEAIN_03349 2.3e-96 yvqK 2.5.1.17 S Adenosyltransferase
HHGCEAIN_03350 1.2e-201 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HHGCEAIN_03351 1.4e-176 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHGCEAIN_03352 1.1e-164 yvrC P ABC transporter substrate-binding protein
HHGCEAIN_03353 1e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHGCEAIN_03354 4.3e-166 yvrE G SMP-30/Gluconolaconase/LRE-like region
HHGCEAIN_03355 0.0 T PhoQ Sensor
HHGCEAIN_03356 5.7e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHGCEAIN_03357 6.2e-35
HHGCEAIN_03358 2.1e-100 yvrI K RNA polymerase
HHGCEAIN_03359 1.6e-15 S YvrJ protein family
HHGCEAIN_03360 3.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
HHGCEAIN_03361 9.9e-60 yvrL S Regulatory protein YrvL
HHGCEAIN_03362 4.5e-146 fhuC 3.6.3.34 HP ABC transporter
HHGCEAIN_03363 1.4e-168 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHGCEAIN_03364 1.5e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHGCEAIN_03365 6.4e-176 fhuD P ABC transporter
HHGCEAIN_03366 4e-122 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HHGCEAIN_03367 3e-233 yvsH E Arginine ornithine antiporter
HHGCEAIN_03368 5.2e-13 S Small spore protein J (Spore_SspJ)
HHGCEAIN_03369 3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HHGCEAIN_03370 3e-166 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HHGCEAIN_03371 3.5e-163 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HHGCEAIN_03372 5.4e-159 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HHGCEAIN_03373 4.2e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HHGCEAIN_03374 1.6e-90 modB P COG4149 ABC-type molybdate transport system, permease component
HHGCEAIN_03375 3.1e-113 yfiK K Regulator
HHGCEAIN_03376 5.6e-171 T Histidine kinase
HHGCEAIN_03377 6.8e-170 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
HHGCEAIN_03378 3e-185 yfiM V ABC-2 type transporter
HHGCEAIN_03379 7.3e-174 yfiN V COG0842 ABC-type multidrug transport system, permease component
HHGCEAIN_03380 5e-156 yvgN S reductase
HHGCEAIN_03381 2.3e-84 yvgO
HHGCEAIN_03382 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HHGCEAIN_03383 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HHGCEAIN_03384 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HHGCEAIN_03385 0.0 helD 3.6.4.12 L DNA helicase
HHGCEAIN_03387 1e-97 yvgT S membrane
HHGCEAIN_03388 9.1e-139 S Metallo-peptidase family M12
HHGCEAIN_03389 8.6e-72 bdbC O Required for disulfide bond formation in some proteins
HHGCEAIN_03390 7.7e-99 bdbD O Thioredoxin
HHGCEAIN_03391 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HHGCEAIN_03392 0.0 copA 3.6.3.54 P P-type ATPase
HHGCEAIN_03393 9.9e-29 copZ P Heavy-metal-associated domain
HHGCEAIN_03394 1.4e-47 csoR S transcriptional
HHGCEAIN_03395 8.9e-187 yvaA 1.1.1.371 S Oxidoreductase
HHGCEAIN_03396 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HHGCEAIN_03397 5.6e-250 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHGCEAIN_03398 1e-44 ytnI O COG0695 Glutaredoxin and related proteins
HHGCEAIN_03399 2e-175 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHGCEAIN_03400 2.2e-137 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HHGCEAIN_03401 5.1e-117 tcyM U Binding-protein-dependent transport system inner membrane component
HHGCEAIN_03402 2.1e-118 tcyL P Binding-protein-dependent transport system inner membrane component
HHGCEAIN_03403 2.4e-131 tcyK M Bacterial periplasmic substrate-binding proteins
HHGCEAIN_03404 1.7e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
HHGCEAIN_03405 2.5e-100 ytmI K Acetyltransferase (GNAT) domain
HHGCEAIN_03406 2.2e-157 ytlI K LysR substrate binding domain
HHGCEAIN_03407 5.9e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHGCEAIN_03408 1.8e-42 yrdF K ribonuclease inhibitor
HHGCEAIN_03410 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HHGCEAIN_03411 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHGCEAIN_03412 1.6e-142 est 3.1.1.1 S Carboxylesterase
HHGCEAIN_03413 4.2e-20 secG U Preprotein translocase subunit SecG
HHGCEAIN_03414 6e-35 yvzC K Transcriptional
HHGCEAIN_03415 1.6e-67 K transcriptional
HHGCEAIN_03416 9.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
HHGCEAIN_03417 1.4e-50 yodB K transcriptional
HHGCEAIN_03418 6.5e-241 T His Kinase A (phosphoacceptor) domain
HHGCEAIN_03419 1.3e-119 K Transcriptional regulatory protein, C terminal
HHGCEAIN_03420 3.2e-133 mutG S ABC-2 family transporter protein
HHGCEAIN_03421 1.3e-120 spaE S ABC-2 family transporter protein
HHGCEAIN_03422 1.3e-125 mutF V ABC transporter, ATP-binding protein
HHGCEAIN_03423 9.8e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HHGCEAIN_03424 5.1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HHGCEAIN_03425 1e-108 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HHGCEAIN_03426 5.6e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HHGCEAIN_03427 1.7e-56 yvbF K Belongs to the GbsR family
HHGCEAIN_03428 4.1e-108 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HHGCEAIN_03429 7.4e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HHGCEAIN_03430 8.6e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HHGCEAIN_03431 9.7e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HHGCEAIN_03432 2.8e-94 yvbF K Belongs to the GbsR family
HHGCEAIN_03433 4.4e-104 yvbG U UPF0056 membrane protein
HHGCEAIN_03434 2.6e-113 exoY M Membrane
HHGCEAIN_03435 0.0 tcaA S response to antibiotic
HHGCEAIN_03436 1.4e-78 yvbK 3.1.3.25 K acetyltransferase
HHGCEAIN_03437 7.8e-206 EGP Major facilitator Superfamily
HHGCEAIN_03438 4.2e-172
HHGCEAIN_03439 2e-123 S GlcNAc-PI de-N-acetylase
HHGCEAIN_03440 2.4e-141 C WbqC-like protein family
HHGCEAIN_03441 8.3e-141 M Protein involved in cellulose biosynthesis
HHGCEAIN_03442 1.3e-219 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HHGCEAIN_03443 1.4e-167 5.1.3.2 M GDP-mannose 4,6 dehydratase
HHGCEAIN_03444 7.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HHGCEAIN_03445 9.5e-250 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHGCEAIN_03446 7.3e-223 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HHGCEAIN_03447 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHGCEAIN_03448 6.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HHGCEAIN_03449 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHGCEAIN_03450 1.6e-216 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HHGCEAIN_03451 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHGCEAIN_03452 8.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HHGCEAIN_03453 2.3e-31 araE EGP Major facilitator Superfamily
HHGCEAIN_03454 2.8e-211 araE EGP Major facilitator Superfamily
HHGCEAIN_03455 6.7e-201 araR K transcriptional
HHGCEAIN_03456 1.2e-188 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHGCEAIN_03457 1.1e-13 yvbU K Transcriptional regulator
HHGCEAIN_03458 1.7e-96 yvbU K Transcriptional regulator
HHGCEAIN_03459 2.8e-152 yvbV EG EamA-like transporter family
HHGCEAIN_03460 3.2e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HHGCEAIN_03462 6.7e-148 ybbH_1 K RpiR family transcriptional regulator
HHGCEAIN_03463 6.6e-295 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
HHGCEAIN_03464 2.3e-219 gntP EG COG2610 H gluconate symporter and related permeases
HHGCEAIN_03465 3.5e-129 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HHGCEAIN_03466 1.7e-265 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HHGCEAIN_03467 1.8e-133 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HHGCEAIN_03468 2.1e-208 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHGCEAIN_03469 1.4e-117 yvfI K COG2186 Transcriptional regulators
HHGCEAIN_03470 3.8e-296 yvfH C L-lactate permease
HHGCEAIN_03471 4.4e-231 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HHGCEAIN_03472 2.7e-32 yvfG S YvfG protein
HHGCEAIN_03473 2.3e-176 yvfF GM Exopolysaccharide biosynthesis protein
HHGCEAIN_03474 2.7e-216 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HHGCEAIN_03475 1.1e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HHGCEAIN_03476 1.8e-102 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HHGCEAIN_03477 5.2e-268 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHGCEAIN_03478 2e-186 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HHGCEAIN_03479 2e-197 epsI GM pyruvyl transferase
HHGCEAIN_03480 4.6e-191 epsH GT2 S Glycosyltransferase like family 2
HHGCEAIN_03481 1.4e-201 epsG S EpsG family
HHGCEAIN_03482 3.8e-199 epsF GT4 M Glycosyl transferases group 1
HHGCEAIN_03483 8.6e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HHGCEAIN_03484 1.8e-212 epsD GT4 M Glycosyl transferase 4-like
HHGCEAIN_03485 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HHGCEAIN_03486 7.1e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HHGCEAIN_03487 3.3e-116 ywqC M biosynthesis protein
HHGCEAIN_03488 5.1e-78 slr K transcriptional
HHGCEAIN_03489 6.5e-236 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HHGCEAIN_03491 1.3e-85 ywjB H RibD C-terminal domain
HHGCEAIN_03492 1.7e-130 CH FAD binding domain
HHGCEAIN_03493 9.3e-74 S Metallo-beta-lactamase superfamily
HHGCEAIN_03494 3e-105 yyaS S Membrane
HHGCEAIN_03495 1e-82 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHGCEAIN_03496 1.2e-93 padC Q Phenolic acid decarboxylase
HHGCEAIN_03497 9.4e-50 MA20_18690 S Protein of unknown function (DUF3237)
HHGCEAIN_03498 6.1e-31 S Protein of unknown function (DUF1433)
HHGCEAIN_03499 5e-17 S Protein of unknown function (DUF1433)
HHGCEAIN_03500 4.8e-19 S Protein of unknown function (DUF1433)
HHGCEAIN_03501 5.8e-253 I Pfam Lipase (class 3)
HHGCEAIN_03502 7.6e-33
HHGCEAIN_03504 2.8e-279 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
HHGCEAIN_03505 7.8e-214 rafB P LacY proton/sugar symporter
HHGCEAIN_03506 4.6e-177 scrR K transcriptional
HHGCEAIN_03507 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHGCEAIN_03508 7.2e-158 yraN K Transcriptional regulator
HHGCEAIN_03509 3.7e-202 yraM S PrpF protein
HHGCEAIN_03510 8.3e-241 EGP Sugar (and other) transporter
HHGCEAIN_03511 5.3e-89
HHGCEAIN_03512 6.4e-102 yvdD 3.2.2.10 S Belongs to the LOG family
HHGCEAIN_03513 7.1e-50 yvdC S MazG nucleotide pyrophosphohydrolase domain
HHGCEAIN_03514 6.4e-277 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HHGCEAIN_03515 2e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HHGCEAIN_03516 2.9e-179 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHGCEAIN_03517 1.3e-76 M Ribonuclease
HHGCEAIN_03518 1.5e-130 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HHGCEAIN_03519 1.4e-35 crh G Phosphocarrier protein Chr
HHGCEAIN_03520 3.1e-170 whiA K May be required for sporulation
HHGCEAIN_03521 3.2e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HHGCEAIN_03522 3.3e-166 rapZ S Displays ATPase and GTPase activities
HHGCEAIN_03523 8.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HHGCEAIN_03524 5.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHGCEAIN_03525 2.1e-117 usp CBM50 M protein conserved in bacteria
HHGCEAIN_03526 4.2e-267 S COG0457 FOG TPR repeat
HHGCEAIN_03527 6.8e-182 sasA T Histidine kinase
HHGCEAIN_03528 4.4e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHGCEAIN_03529 0.0 msbA2 3.6.3.44 V ABC transporter
HHGCEAIN_03530 2.2e-108 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HHGCEAIN_03531 1.2e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HHGCEAIN_03532 6.7e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HHGCEAIN_03533 1.4e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HHGCEAIN_03534 8.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HHGCEAIN_03535 1.7e-219 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HHGCEAIN_03536 1.4e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HHGCEAIN_03537 1.8e-199 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HHGCEAIN_03538 7.2e-135 yvpB NU protein conserved in bacteria
HHGCEAIN_03539 2.4e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HHGCEAIN_03540 1.3e-111 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HHGCEAIN_03541 3.4e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHGCEAIN_03542 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHGCEAIN_03543 2.6e-214 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHGCEAIN_03544 4.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHGCEAIN_03545 7.6e-132 yvoA K transcriptional
HHGCEAIN_03546 3.2e-101 yxaF K Transcriptional regulator
HHGCEAIN_03547 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HHGCEAIN_03548 9.1e-46 yvlD S Membrane
HHGCEAIN_03549 9.6e-26 pspB KT PspC domain
HHGCEAIN_03550 5.6e-163 yvlB S Putative adhesin
HHGCEAIN_03551 4e-46 yvlA
HHGCEAIN_03552 3.6e-30 yvkN
HHGCEAIN_03553 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHGCEAIN_03554 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHGCEAIN_03555 7.6e-33 csbA S protein conserved in bacteria
HHGCEAIN_03556 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HHGCEAIN_03557 1e-91 yvkB K Transcriptional regulator
HHGCEAIN_03558 6.5e-222 yvkA EGP Major facilitator Superfamily
HHGCEAIN_03559 4.5e-25 yuaB
HHGCEAIN_03561 1.1e-217 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHGCEAIN_03562 2.9e-54 swrA S Swarming motility protein
HHGCEAIN_03563 3.8e-249 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HHGCEAIN_03564 6.9e-190 ywoF P Right handed beta helix region
HHGCEAIN_03565 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HHGCEAIN_03566 2.3e-122 ftsE D cell division ATP-binding protein FtsE
HHGCEAIN_03567 5.2e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
HHGCEAIN_03568 1.5e-147 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HHGCEAIN_03569 9.4e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHGCEAIN_03570 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHGCEAIN_03571 4.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHGCEAIN_03572 6.8e-68
HHGCEAIN_03573 1.3e-09 fliT S bacterial-type flagellum organization
HHGCEAIN_03574 7e-63 fliS N flagellar protein FliS
HHGCEAIN_03575 9.5e-238 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HHGCEAIN_03576 1.9e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHGCEAIN_03577 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HHGCEAIN_03578 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HHGCEAIN_03579 8.3e-78 yviE
HHGCEAIN_03580 7.4e-161 flgL N Belongs to the bacterial flagellin family
HHGCEAIN_03581 2.2e-271 flgK N flagellar hook-associated protein
HHGCEAIN_03582 5.4e-78 flgN NOU FlgN protein
HHGCEAIN_03583 2.3e-38 flgM KNU Negative regulator of flagellin synthesis
HHGCEAIN_03584 3.9e-72 yvyF S flagellar protein
HHGCEAIN_03585 6.2e-62 comFC S Phosphoribosyl transferase domain
HHGCEAIN_03586 8.2e-42 comFB S Late competence development protein ComFB
HHGCEAIN_03587 2.9e-249 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HHGCEAIN_03588 8.1e-154 degV S protein conserved in bacteria
HHGCEAIN_03589 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHGCEAIN_03590 2.4e-180 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HHGCEAIN_03591 1e-116 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HHGCEAIN_03592 4.2e-170 yvhJ K Transcriptional regulator
HHGCEAIN_03593 1.4e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HHGCEAIN_03594 5.6e-225 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HHGCEAIN_03595 1.9e-141 tuaG GT2 M Glycosyltransferase like family 2
HHGCEAIN_03596 1.6e-107 tuaF M protein involved in exopolysaccharide biosynthesis
HHGCEAIN_03597 5.4e-251 tuaE M Teichuronic acid biosynthesis protein
HHGCEAIN_03598 1.5e-242 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHGCEAIN_03599 1.4e-212 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HHGCEAIN_03600 4.8e-255 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHGCEAIN_03601 1.4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HHGCEAIN_03602 3.3e-211 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HHGCEAIN_03603 1.1e-303 lytB 3.5.1.28 D Stage II sporulation protein
HHGCEAIN_03604 1e-29
HHGCEAIN_03605 5.2e-138 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HHGCEAIN_03606 1.2e-184 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HHGCEAIN_03607 2.1e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HHGCEAIN_03608 1e-178 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HHGCEAIN_03609 3.4e-136 tagG GM Transport permease protein
HHGCEAIN_03610 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HHGCEAIN_03611 1.3e-258 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HHGCEAIN_03612 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HHGCEAIN_03613 1.4e-139 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HHGCEAIN_03614 7.6e-203 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HHGCEAIN_03615 1.5e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHGCEAIN_03616 3.8e-184 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HHGCEAIN_03617 3.2e-251 gerBA EG Spore germination protein
HHGCEAIN_03618 1.4e-190 gerBB E Spore germination protein
HHGCEAIN_03619 1.7e-171 gerAC S Spore germination protein
HHGCEAIN_03620 4.4e-258 GT2,GT4 J Glycosyl transferase family 2
HHGCEAIN_03621 1.6e-239 ywtG EGP Major facilitator Superfamily
HHGCEAIN_03622 1.1e-173 ywtF K Transcriptional regulator
HHGCEAIN_03623 1.4e-153 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HHGCEAIN_03624 4.1e-29 yttA 2.7.13.3 S Pfam Transposase IS66
HHGCEAIN_03625 8.6e-229 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HHGCEAIN_03626 3.8e-20 ywtC
HHGCEAIN_03627 1.2e-216 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HHGCEAIN_03628 2.3e-70 pgsC S biosynthesis protein
HHGCEAIN_03629 4e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HHGCEAIN_03630 1.2e-184 gerKA EG Spore germination protein
HHGCEAIN_03631 2.1e-178 gerKB E Spore germination protein
HHGCEAIN_03632 3.1e-50 gerKC S Spore germination B3/ GerAC like, C-terminal
HHGCEAIN_03633 4.4e-113 gerKC S Spore germination B3/ GerAC like, C-terminal
HHGCEAIN_03634 3.7e-174 rbsR K transcriptional
HHGCEAIN_03635 6.5e-154 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHGCEAIN_03636 9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HHGCEAIN_03637 8.4e-271 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HHGCEAIN_03638 3.5e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
HHGCEAIN_03639 2.6e-158 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HHGCEAIN_03640 3.9e-85 batE T Sh3 type 3 domain protein
HHGCEAIN_03641 7.5e-89 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HHGCEAIN_03642 9e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HHGCEAIN_03643 9.6e-303 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HHGCEAIN_03644 2.7e-163 alsR K LysR substrate binding domain
HHGCEAIN_03645 1.1e-232 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HHGCEAIN_03646 1.2e-115 ywrJ
HHGCEAIN_03647 1.5e-113 cotB
HHGCEAIN_03648 8.5e-204 cotH M Spore Coat
HHGCEAIN_03649 1.2e-06
HHGCEAIN_03650 6.2e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHGCEAIN_03652 1.6e-291 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HHGCEAIN_03653 3e-81 ywrC K Transcriptional regulator
HHGCEAIN_03654 2e-98 ywrB P Chromate transporter
HHGCEAIN_03655 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
HHGCEAIN_03656 3.3e-102
HHGCEAIN_03657 4.9e-63
HHGCEAIN_03658 1.3e-73 S SMI1 / KNR4 family
HHGCEAIN_03659 3.6e-18
HHGCEAIN_03660 8.4e-59 S SUKH-4 immunity protein
HHGCEAIN_03661 4.9e-231 ywqJ S Pre-toxin TG
HHGCEAIN_03662 1.4e-35 ywqI S Family of unknown function (DUF5344)
HHGCEAIN_03663 1.7e-17 S Domain of unknown function (DUF5082)
HHGCEAIN_03664 4.2e-144 ywqG S Domain of unknown function (DUF1963)
HHGCEAIN_03665 1e-240 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHGCEAIN_03666 8.2e-137 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HHGCEAIN_03667 8.5e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HHGCEAIN_03668 1.2e-105 ywqC M biosynthesis protein
HHGCEAIN_03669 2.6e-15
HHGCEAIN_03670 2.9e-301 ywqB S SWIM zinc finger
HHGCEAIN_03671 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HHGCEAIN_03672 7.2e-150 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HHGCEAIN_03673 5.4e-136 glcR K DeoR C terminal sensor domain
HHGCEAIN_03674 5.4e-56 ssbB L Single-stranded DNA-binding protein
HHGCEAIN_03675 2.5e-56 ywpG
HHGCEAIN_03676 9.9e-68 ywpF S YwpF-like protein
HHGCEAIN_03677 5.9e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HHGCEAIN_03678 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHGCEAIN_03679 1.1e-192 S aspartate phosphatase
HHGCEAIN_03680 1.5e-136 flhP N flagellar basal body
HHGCEAIN_03681 8e-127 flhO N flagellar basal body
HHGCEAIN_03682 2.7e-180 mbl D Rod shape-determining protein
HHGCEAIN_03683 1.8e-44 spoIIID K Stage III sporulation protein D
HHGCEAIN_03684 1.1e-71 ywoH K transcriptional
HHGCEAIN_03685 4.1e-212 ywoG EGP Major facilitator Superfamily
HHGCEAIN_03686 2.4e-270 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HHGCEAIN_03687 9.8e-242 ywoD EGP Major facilitator superfamily
HHGCEAIN_03688 8.5e-99 phzA Q Isochorismatase family
HHGCEAIN_03689 3.9e-226 amt P Ammonium transporter
HHGCEAIN_03690 1.7e-57 nrgB K Belongs to the P(II) protein family
HHGCEAIN_03691 1.1e-206 ftsW D Belongs to the SEDS family
HHGCEAIN_03692 1.3e-99 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HHGCEAIN_03693 6.4e-67 ywnJ S VanZ like family
HHGCEAIN_03694 2.7e-120 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HHGCEAIN_03695 3.9e-87 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HHGCEAIN_03696 3.1e-11 ywnC S Family of unknown function (DUF5362)
HHGCEAIN_03697 1.3e-67 ywnF S Family of unknown function (DUF5392)
HHGCEAIN_03698 1.2e-274 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHGCEAIN_03699 8.6e-16 yqgA
HHGCEAIN_03700 1.3e-50 ywnC S Family of unknown function (DUF5362)
HHGCEAIN_03701 3.7e-90 ywnB S NAD(P)H-binding
HHGCEAIN_03702 6.1e-67 ywnA K Transcriptional regulator
HHGCEAIN_03703 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HHGCEAIN_03704 5.5e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HHGCEAIN_03705 2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HHGCEAIN_03706 1.2e-09 csbD K CsbD-like
HHGCEAIN_03707 3.9e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HHGCEAIN_03708 1e-142 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HHGCEAIN_03710 8.1e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HHGCEAIN_03711 1.3e-112 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HHGCEAIN_03712 1.2e-180 spoIID D Stage II sporulation protein D
HHGCEAIN_03713 8.2e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHGCEAIN_03714 1.7e-131 ywmB S TATA-box binding
HHGCEAIN_03715 6.2e-32 ywzB S membrane
HHGCEAIN_03716 4.3e-88 ywmA
HHGCEAIN_03717 5.3e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HHGCEAIN_03718 1e-265 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHGCEAIN_03719 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHGCEAIN_03720 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHGCEAIN_03721 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHGCEAIN_03722 3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHGCEAIN_03723 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHGCEAIN_03724 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
HHGCEAIN_03725 2.8e-61 atpI S ATP synthase
HHGCEAIN_03726 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHGCEAIN_03727 9.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHGCEAIN_03728 3.2e-95 ywlG S Belongs to the UPF0340 family
HHGCEAIN_03729 4.6e-79 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HHGCEAIN_03730 1.1e-72 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHGCEAIN_03731 6.2e-86 mntP P Probably functions as a manganese efflux pump
HHGCEAIN_03732 2.9e-185 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHGCEAIN_03733 3.7e-73 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HHGCEAIN_03734 2.1e-115 spoIIR S stage II sporulation protein R
HHGCEAIN_03735 9.7e-59 ywlA S Uncharacterised protein family (UPF0715)
HHGCEAIN_03737 8.5e-151 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHGCEAIN_03738 7.5e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHGCEAIN_03739 2.1e-64 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHGCEAIN_03740 2.7e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HHGCEAIN_03741 1.1e-151 ywkB S Membrane transport protein
HHGCEAIN_03742 0.0 sfcA 1.1.1.38 C malic enzyme
HHGCEAIN_03743 8e-100 tdk 2.7.1.21 F thymidine kinase
HHGCEAIN_03744 1.1e-32 rpmE J Binds the 23S rRNA
HHGCEAIN_03745 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HHGCEAIN_03746 2e-172 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HHGCEAIN_03747 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHGCEAIN_03748 7.1e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHGCEAIN_03749 2.7e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HHGCEAIN_03750 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
HHGCEAIN_03751 1.8e-90 ywjG S Domain of unknown function (DUF2529)
HHGCEAIN_03752 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHGCEAIN_03753 7.1e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHGCEAIN_03754 0.0 fadF C COG0247 Fe-S oxidoreductase
HHGCEAIN_03755 1.1e-201 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HHGCEAIN_03756 2.1e-174 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HHGCEAIN_03757 9.3e-43 ywjC
HHGCEAIN_03758 0.0 ywjA V ABC transporter
HHGCEAIN_03759 4.7e-288 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHGCEAIN_03760 1.4e-116 narI 1.7.5.1 C nitrate reductase, gamma
HHGCEAIN_03761 4e-85 narJ 1.7.5.1 C nitrate reductase
HHGCEAIN_03762 3.8e-292 narH 1.7.5.1 C Nitrate reductase, beta
HHGCEAIN_03763 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHGCEAIN_03764 1.4e-78 arfM T cyclic nucleotide binding
HHGCEAIN_03765 1.6e-126 ywiC S YwiC-like protein
HHGCEAIN_03766 2.2e-87 fnr K helix_turn_helix, cAMP Regulatory protein
HHGCEAIN_03767 4.3e-209 narK P COG2223 Nitrate nitrite transporter
HHGCEAIN_03768 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HHGCEAIN_03769 1.5e-71 ywiB S protein conserved in bacteria
HHGCEAIN_03771 2.3e-88 ywhL CO amine dehydrogenase activity
HHGCEAIN_03772 1e-95 ywhK CO amine dehydrogenase activity
HHGCEAIN_03773 5.8e-78 S aspartate phosphatase
HHGCEAIN_03775 2.3e-167 speB 3.5.3.11 E Belongs to the arginase family
HHGCEAIN_03776 1.6e-157 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HHGCEAIN_03777 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHGCEAIN_03778 3e-72
HHGCEAIN_03779 5.1e-90 ywhD S YwhD family
HHGCEAIN_03780 8.1e-117 ywhC S Peptidase family M50
HHGCEAIN_03781 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HHGCEAIN_03782 9.8e-68 ywhA K Transcriptional regulator
HHGCEAIN_03783 4.9e-241 yhdG_1 E C-terminus of AA_permease
HHGCEAIN_03784 1.7e-87 ywgA 2.1.1.72, 3.1.21.3
HHGCEAIN_03785 9e-253 ywfO S COG1078 HD superfamily phosphohydrolases
HHGCEAIN_03786 6.9e-36 ywzC S Belongs to the UPF0741 family
HHGCEAIN_03787 1.6e-103 rsfA_1
HHGCEAIN_03788 4.1e-50 padR K PadR family transcriptional regulator
HHGCEAIN_03789 4e-85 S membrane
HHGCEAIN_03790 2.2e-152 V ABC transporter, ATP-binding protein
HHGCEAIN_03791 1.1e-162 yhcI S ABC transporter (permease)
HHGCEAIN_03794 6.1e-163
HHGCEAIN_03796 2e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HHGCEAIN_03797 1.3e-154 cysL K Transcriptional regulator
HHGCEAIN_03798 6.7e-152 MA20_14895 S Conserved hypothetical protein 698
HHGCEAIN_03799 8.1e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HHGCEAIN_03800 4.8e-145 ywfI C May function as heme-dependent peroxidase
HHGCEAIN_03801 2.3e-14 K Helix-turn-helix XRE-family like proteins
HHGCEAIN_03803 2.6e-138 IQ Enoyl-(Acyl carrier protein) reductase
HHGCEAIN_03804 7.1e-228 ywfG 2.6.1.83 E Aminotransferase class I and II
HHGCEAIN_03805 6.1e-208 bacE EGP Major facilitator Superfamily
HHGCEAIN_03806 1e-262 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HHGCEAIN_03807 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHGCEAIN_03808 4.9e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HHGCEAIN_03809 1.2e-67 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HHGCEAIN_03810 4.4e-217 ywfA EGP Major facilitator Superfamily
HHGCEAIN_03811 6e-195 tcaB EGP Major facilitator Superfamily
HHGCEAIN_03812 4.2e-256 lysP E amino acid
HHGCEAIN_03813 0.0 rocB E arginine degradation protein
HHGCEAIN_03814 2.1e-293 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HHGCEAIN_03815 1.1e-245 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HHGCEAIN_03816 2.6e-61
HHGCEAIN_03817 1.3e-84 spsL 5.1.3.13 M Spore Coat
HHGCEAIN_03818 5.6e-155 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HHGCEAIN_03819 1e-176 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HHGCEAIN_03820 4.5e-132 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHGCEAIN_03821 1.4e-165 spsG M Spore Coat
HHGCEAIN_03822 2.6e-124 spsF M Spore Coat
HHGCEAIN_03823 1.4e-209 spsE 2.5.1.56 M acid synthase
HHGCEAIN_03824 6.6e-151 spsD 2.3.1.210 K Spore Coat
HHGCEAIN_03825 1e-215 spsC E Belongs to the DegT DnrJ EryC1 family
HHGCEAIN_03826 2.7e-258 spsB M Capsule polysaccharide biosynthesis protein
HHGCEAIN_03827 9.4e-141 spsA M Spore Coat
HHGCEAIN_03828 1.6e-62 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HHGCEAIN_03829 5e-55 ywdK S small membrane protein
HHGCEAIN_03830 5.6e-226 ywdJ F Xanthine uracil
HHGCEAIN_03831 5.4e-36 ywdI S Family of unknown function (DUF5327)
HHGCEAIN_03832 5.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHGCEAIN_03833 9.2e-147 ywdF GT2,GT4 S Glycosyltransferase like family 2
HHGCEAIN_03835 1.9e-144 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HHGCEAIN_03836 1.5e-20 ywdA
HHGCEAIN_03837 5.8e-269 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
HHGCEAIN_03838 2.1e-247 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHGCEAIN_03839 7e-150 sacT K transcriptional antiterminator
HHGCEAIN_03841 0.0 vpr O Belongs to the peptidase S8 family
HHGCEAIN_03842 6.4e-182 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHGCEAIN_03843 2.7e-118 M1-869 K WYL domain
HHGCEAIN_03844 2e-125 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHGCEAIN_03845 3.2e-42 S Ketosteroid isomerase-related protein
HHGCEAIN_03846 2.1e-32 S Stress responsive A/B Barrel Domain
HHGCEAIN_03847 6.8e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HHGCEAIN_03848 1.8e-207 rodA D Belongs to the SEDS family
HHGCEAIN_03849 6.3e-68 ysnE K acetyltransferase
HHGCEAIN_03850 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
HHGCEAIN_03851 1.6e-61 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HHGCEAIN_03852 2.3e-110 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HHGCEAIN_03853 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HHGCEAIN_03854 1.6e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HHGCEAIN_03855 8.4e-27 ywzA S membrane
HHGCEAIN_03856 6.4e-282 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HHGCEAIN_03857 2.1e-208 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHGCEAIN_03858 9.6e-60 gtcA S GtrA-like protein
HHGCEAIN_03859 1.1e-96 ywcC K Bacterial regulatory proteins, tetR family
HHGCEAIN_03861 8.3e-125 H Methionine biosynthesis protein MetW
HHGCEAIN_03862 6.8e-119 S Streptomycin biosynthesis protein StrF
HHGCEAIN_03863 6.3e-108 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HHGCEAIN_03864 1e-232 ywbN P Dyp-type peroxidase family protein
HHGCEAIN_03865 2.4e-132 ycdO P periplasmic lipoprotein involved in iron transport
HHGCEAIN_03866 3.6e-194 P COG0672 High-affinity Fe2 Pb2 permease
HHGCEAIN_03867 1.8e-108 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HHGCEAIN_03868 1.4e-126 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HHGCEAIN_03869 2.6e-150 ywbI K Transcriptional regulator
HHGCEAIN_03870 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HHGCEAIN_03871 2.2e-109 ywbG M effector of murein hydrolase
HHGCEAIN_03872 1.5e-26 ywbE S Uncharacterized conserved protein (DUF2196)
HHGCEAIN_03873 1.8e-128 mta K transcriptional
HHGCEAIN_03874 7.1e-156 yjfC O Predicted Zn-dependent protease (DUF2268)
HHGCEAIN_03875 4.9e-221 ywbD 2.1.1.191 J Methyltransferase
HHGCEAIN_03876 2.9e-66 ywbC 4.4.1.5 E glyoxalase
HHGCEAIN_03877 1.6e-241 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHGCEAIN_03878 7.8e-252 epr 3.4.21.62 O Belongs to the peptidase S8 family
HHGCEAIN_03879 1.6e-160 gspA M General stress
HHGCEAIN_03881 2.9e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HHGCEAIN_03882 1.9e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HHGCEAIN_03883 4.7e-12 S D-Ala-teichoic acid biosynthesis protein
HHGCEAIN_03884 1.5e-288 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHGCEAIN_03885 6.5e-226 dltB M membrane protein involved in D-alanine export
HHGCEAIN_03886 5.6e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHGCEAIN_03887 5.6e-193 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHGCEAIN_03888 5.5e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HHGCEAIN_03889 1.5e-247 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHGCEAIN_03890 6.2e-49 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HHGCEAIN_03891 3.6e-244 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHGCEAIN_03892 7.5e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HHGCEAIN_03893 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HHGCEAIN_03894 5.2e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HHGCEAIN_03895 2.4e-168 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHGCEAIN_03896 3.3e-178 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHGCEAIN_03897 2.2e-165 cbrA3 P Periplasmic binding protein
HHGCEAIN_03898 1.2e-50 arsR K transcriptional
HHGCEAIN_03899 3.9e-224 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HHGCEAIN_03900 1.5e-43 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HHGCEAIN_03901 1.9e-47 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HHGCEAIN_03902 1.8e-224 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHGCEAIN_03903 1.8e-278 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHGCEAIN_03904 1.1e-161 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HHGCEAIN_03905 3.1e-178 manA 5.3.1.8 G mannose-6-phosphate isomerase
HHGCEAIN_03906 6.9e-206 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HHGCEAIN_03907 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HHGCEAIN_03908 2e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HHGCEAIN_03909 7e-248 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HHGCEAIN_03910 2e-109 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHGCEAIN_03911 9e-29 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHGCEAIN_03912 4.8e-286 cydD V ATP-binding protein
HHGCEAIN_03913 6.4e-307 cydD V ATP-binding
HHGCEAIN_03914 4.8e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HHGCEAIN_03915 3.8e-265 cydA 1.10.3.14 C oxidase, subunit
HHGCEAIN_03916 2.3e-211 cimH C COG3493 Na citrate symporter
HHGCEAIN_03917 1.2e-149 yxkH G Polysaccharide deacetylase
HHGCEAIN_03918 6.5e-204 msmK P Belongs to the ABC transporter superfamily
HHGCEAIN_03919 2e-155 lrp QT PucR C-terminal helix-turn-helix domain
HHGCEAIN_03920 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHGCEAIN_03922 9.7e-83 yxkC S Domain of unknown function (DUF4352)
HHGCEAIN_03923 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHGCEAIN_03924 2.6e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HHGCEAIN_03927 3e-81 yxjI S LURP-one-related
HHGCEAIN_03928 9.4e-214 yxjG 2.1.1.14 E Methionine synthase
HHGCEAIN_03929 1.8e-143 rlmA 2.1.1.187 Q Methyltransferase domain
HHGCEAIN_03930 6.8e-208 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHGCEAIN_03931 6e-67 T Domain of unknown function (DUF4163)
HHGCEAIN_03932 2.8e-45 yxiS
HHGCEAIN_03933 6.4e-181 L DNA synthesis involved in DNA repair
HHGCEAIN_03934 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HHGCEAIN_03935 1.5e-178 citH C Citrate transporter
HHGCEAIN_03936 3.8e-136 exoK GH16 M licheninase activity
HHGCEAIN_03937 1.8e-142 licT K transcriptional antiterminator
HHGCEAIN_03938 1.6e-219 yxiO S COG2270 Permeases of the major facilitator superfamily
HHGCEAIN_03939 8.6e-249 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HHGCEAIN_03941 1.4e-21
HHGCEAIN_03942 5.8e-14 S YxiJ-like protein
HHGCEAIN_03943 3.9e-111
HHGCEAIN_03944 5.6e-77
HHGCEAIN_03945 9.9e-65 yxiG
HHGCEAIN_03946 4.8e-57 yxxG
HHGCEAIN_03948 5.7e-197 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
HHGCEAIN_03949 1.5e-142 yxxF EG EamA-like transporter family
HHGCEAIN_03950 4.1e-72 yxiE T Belongs to the universal stress protein A family
HHGCEAIN_03951 1.1e-275 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHGCEAIN_03952 6.8e-307 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHGCEAIN_03953 1.7e-46 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HHGCEAIN_03954 2e-146 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
HHGCEAIN_03955 9.7e-163 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HHGCEAIN_03956 2e-262 L Z1 domain
HHGCEAIN_03957 1.5e-79 S Putative PD-(D/E)XK family member, (DUF4420)
HHGCEAIN_03958 3.3e-197 S AIPR protein
HHGCEAIN_03959 2.2e-265 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HHGCEAIN_03960 8.5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HHGCEAIN_03961 1.1e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
HHGCEAIN_03962 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HHGCEAIN_03963 9.4e-231 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HHGCEAIN_03964 1e-168 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HHGCEAIN_03965 5e-249 lysP E amino acid
HHGCEAIN_03966 7.4e-231 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HHGCEAIN_03967 1.2e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHGCEAIN_03968 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHGCEAIN_03969 5.3e-170 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HHGCEAIN_03970 2.1e-146 yidA S hydrolases of the HAD superfamily
HHGCEAIN_03975 7.9e-21 yxeD
HHGCEAIN_03976 2.7e-35
HHGCEAIN_03977 1.2e-169 fhuD P Periplasmic binding protein
HHGCEAIN_03978 2.7e-55 yxeA S Protein of unknown function (DUF1093)
HHGCEAIN_03979 0.0 yxdM V ABC transporter (permease)
HHGCEAIN_03980 1.4e-136 yxdL V ABC transporter, ATP-binding protein
HHGCEAIN_03981 9.6e-175 T PhoQ Sensor
HHGCEAIN_03982 3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHGCEAIN_03983 4.6e-152 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HHGCEAIN_03984 1.4e-145 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HHGCEAIN_03985 6.8e-164 iolH G Xylose isomerase-like TIM barrel
HHGCEAIN_03986 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HHGCEAIN_03987 1e-227 iolF EGP Major facilitator Superfamily
HHGCEAIN_03988 1.8e-172 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HHGCEAIN_03989 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HHGCEAIN_03990 1.6e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HHGCEAIN_03991 8.7e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HHGCEAIN_03992 8.8e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHGCEAIN_03993 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
HHGCEAIN_03994 4.4e-169 iolS C Aldo keto reductase
HHGCEAIN_03995 4.8e-244 csbC EGP Major facilitator Superfamily
HHGCEAIN_03996 0.0 htpG O Molecular chaperone. Has ATPase activity
HHGCEAIN_03997 2.5e-147 IQ Enoyl-(Acyl carrier protein) reductase
HHGCEAIN_03998 1.6e-100 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHGCEAIN_03999 3.5e-192 desK 2.7.13.3 T Histidine kinase
HHGCEAIN_04000 1.2e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HHGCEAIN_04001 1.4e-209 yxbF K Bacterial regulatory proteins, tetR family
HHGCEAIN_04002 4.9e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HHGCEAIN_04003 3.2e-138 S PQQ-like domain
HHGCEAIN_04004 2.7e-57 S Family of unknown function (DUF5391)
HHGCEAIN_04005 4.3e-49 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
HHGCEAIN_04006 1.1e-198 EGP Major facilitator Superfamily
HHGCEAIN_04007 5e-65 yxaI S membrane protein domain
HHGCEAIN_04008 1.1e-93 E Ring-cleavage extradiol dioxygenase
HHGCEAIN_04009 9.4e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HHGCEAIN_04010 8.9e-284 ahpF O Alkyl hydroperoxide reductase
HHGCEAIN_04011 9e-186 G Major royal jelly protein
HHGCEAIN_04012 1e-235 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
HHGCEAIN_04013 3.4e-156 K helix_turn_helix, Deoxyribose operon repressor
HHGCEAIN_04014 1.4e-73 K Integron-associated effector binding protein
HHGCEAIN_04015 5.4e-75 yjhE S Phage tail protein
HHGCEAIN_04016 0.0 L Transposase and inactivated derivatives, TnpA family
HHGCEAIN_04017 7.1e-85 L resolvase
HHGCEAIN_04018 1.3e-78
HHGCEAIN_04020 6e-26 S Protein of unknown function (DUF1657)
HHGCEAIN_04021 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHGCEAIN_04022 2.6e-80 spoVAC S stage V sporulation protein AC
HHGCEAIN_04023 1e-195 spoVAD I Stage V sporulation protein AD
HHGCEAIN_04024 8.5e-57 spoVAE S stage V sporulation protein
HHGCEAIN_04025 5.8e-29 S Protein of unknown function (DUF1657)
HHGCEAIN_04026 4.7e-149 yetF1 S membrane
HHGCEAIN_04027 1.2e-70 S Protein of unknown function (DUF421)
HHGCEAIN_04028 2.7e-285 clsA_1 I PLD-like domain
HHGCEAIN_04029 2.5e-92 S Protein of unknown function (DUF421)
HHGCEAIN_04030 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HHGCEAIN_04031 3.2e-78 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HHGCEAIN_04032 4.9e-143 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HHGCEAIN_04033 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HHGCEAIN_04034 1.6e-82 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HHGCEAIN_04035 5.2e-157 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HHGCEAIN_04036 4e-155 S Fusaric acid resistance protein-like
HHGCEAIN_04037 6.5e-19
HHGCEAIN_04038 3.4e-45 3.6.4.12 L AAA domain
HHGCEAIN_04039 8e-224 3.6.4.12 L AAA domain
HHGCEAIN_04040 9.9e-288 L AAA ATPase domain
HHGCEAIN_04041 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHGCEAIN_04042 7.9e-08 S YyzF-like protein
HHGCEAIN_04045 2.3e-207 yycP
HHGCEAIN_04046 1.9e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HHGCEAIN_04047 9.3e-178 C oxidoreductases (related to aryl-alcohol dehydrogenases)
HHGCEAIN_04048 1.4e-81 yycN 2.3.1.128 K Acetyltransferase
HHGCEAIN_04050 2.1e-197 S Histidine kinase
HHGCEAIN_04051 8.2e-165 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HHGCEAIN_04052 1.5e-253 rocE E amino acid
HHGCEAIN_04053 8.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HHGCEAIN_04054 1.6e-61 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HHGCEAIN_04055 1.3e-42 sdpR K transcriptional
HHGCEAIN_04056 4.7e-253 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HHGCEAIN_04057 8.4e-197 S Major Facilitator Superfamily
HHGCEAIN_04058 1.4e-243 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HHGCEAIN_04059 6.5e-93 K PFAM response regulator receiver
HHGCEAIN_04060 1.9e-63 S Peptidase propeptide and YPEB domain
HHGCEAIN_04061 3.4e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHGCEAIN_04062 6.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HHGCEAIN_04063 3.3e-147 yycI S protein conserved in bacteria
HHGCEAIN_04064 8.2e-257 yycH S protein conserved in bacteria
HHGCEAIN_04065 0.0 vicK 2.7.13.3 T Histidine kinase
HHGCEAIN_04066 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHGCEAIN_04071 3.9e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHGCEAIN_04072 2.5e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHGCEAIN_04073 6.1e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HHGCEAIN_04074 2.2e-25 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HHGCEAIN_04076 2.3e-16 yycC K YycC-like protein
HHGCEAIN_04077 2.1e-214 M Glycosyltransferase Family 4
HHGCEAIN_04078 6.1e-191 S Ecdysteroid kinase
HHGCEAIN_04079 5.2e-231 S Carbamoyl-phosphate synthase L chain, ATP binding domain
HHGCEAIN_04080 1e-219 M Glycosyltransferase Family 4
HHGCEAIN_04081 1.8e-116 S GlcNAc-PI de-N-acetylase
HHGCEAIN_04082 1.9e-80 KLT COG0515 Serine threonine protein kinase
HHGCEAIN_04083 8.3e-73 rplI J binds to the 23S rRNA
HHGCEAIN_04084 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HHGCEAIN_04085 2.5e-148 yybS S membrane
HHGCEAIN_04087 4.9e-79 cotF M Spore coat protein
HHGCEAIN_04088 1.2e-64 ydeP3 K Transcriptional regulator
HHGCEAIN_04089 7.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HHGCEAIN_04090 2.5e-150 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HHGCEAIN_04091 2e-266 sacB 2.4.1.10 GH68 M levansucrase activity
HHGCEAIN_04092 1.2e-301 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HHGCEAIN_04093 1.1e-108 K FCD domain
HHGCEAIN_04094 1.9e-73 dinB S PFAM DinB family protein
HHGCEAIN_04095 1.1e-146 G Major Facilitator Superfamily
HHGCEAIN_04096 4.2e-54 ypaA S Protein of unknown function (DUF1304)
HHGCEAIN_04097 4.4e-112 drgA C nitroreductase
HHGCEAIN_04098 1.6e-65 ydgJ K Winged helix DNA-binding domain
HHGCEAIN_04099 5.3e-148 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HHGCEAIN_04100 3.1e-75 yybA 2.3.1.57 K transcriptional
HHGCEAIN_04101 1.8e-70 yjcF S Acetyltransferase (GNAT) domain
HHGCEAIN_04102 3.3e-19 cadC3 K transcriptional
HHGCEAIN_04103 3.8e-103 S Alpha/beta hydrolase family
HHGCEAIN_04104 2e-27
HHGCEAIN_04105 2.8e-67 ynaF
HHGCEAIN_04106 9.1e-167 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HHGCEAIN_04107 1.6e-213 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HHGCEAIN_04108 1.3e-149 yyaK S CAAX protease self-immunity
HHGCEAIN_04109 3.5e-236 ydjK G Sugar (and other) transporter
HHGCEAIN_04110 5.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHGCEAIN_04111 8.8e-93 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HHGCEAIN_04112 1.4e-60 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HHGCEAIN_04113 1.7e-139 xth 3.1.11.2 L exodeoxyribonuclease III
HHGCEAIN_04114 4.5e-86 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHGCEAIN_04115 1.2e-95 adaA 3.2.2.21 K Transcriptional regulator
HHGCEAIN_04116 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHGCEAIN_04117 8.4e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHGCEAIN_04118 3.6e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
HHGCEAIN_04119 1.3e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHGCEAIN_04120 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHGCEAIN_04121 2.3e-33 yyzM S protein conserved in bacteria
HHGCEAIN_04122 2.4e-168 yyaD S Membrane
HHGCEAIN_04123 4.5e-57 4.2.1.103 K FR47-like protein
HHGCEAIN_04124 1.1e-107 yyaC S Sporulation protein YyaC
HHGCEAIN_04125 4.3e-147 spo0J K Belongs to the ParB family
HHGCEAIN_04126 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
HHGCEAIN_04127 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HHGCEAIN_04128 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HHGCEAIN_04129 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHGCEAIN_04130 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHGCEAIN_04131 8.2e-106 jag S single-stranded nucleic acid binding R3H
HHGCEAIN_04132 4.3e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHGCEAIN_04133 1.2e-50 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)