ORF_ID e_value Gene_name EC_number CAZy COGs Description
MHFBIMFO_00001 9e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHFBIMFO_00002 7e-209 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHFBIMFO_00003 2.4e-33 yaaA S S4 domain
MHFBIMFO_00004 4.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHFBIMFO_00005 6.2e-10 yaaB S Domain of unknown function (DUF370)
MHFBIMFO_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHFBIMFO_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHFBIMFO_00008 1.2e-199 M1-161 T HD domain
MHFBIMFO_00010 4.3e-42 S COG NOG14552 non supervised orthologous group
MHFBIMFO_00013 5.3e-43
MHFBIMFO_00014 5.8e-16 csfB S Inhibitor of sigma-G Gin
MHFBIMFO_00015 1.6e-282 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MHFBIMFO_00016 2e-120 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHFBIMFO_00017 9.8e-55 yaaQ S protein conserved in bacteria
MHFBIMFO_00018 1.5e-71 yaaR S protein conserved in bacteria
MHFBIMFO_00019 7.3e-186 holB 2.7.7.7 L DNA polymerase III
MHFBIMFO_00020 1.7e-148 yaaT S stage 0 sporulation protein
MHFBIMFO_00021 3.3e-61 yabA L Involved in initiation control of chromosome replication
MHFBIMFO_00022 2.7e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
MHFBIMFO_00023 7.1e-49 yazA L endonuclease containing a URI domain
MHFBIMFO_00024 2.6e-163 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHFBIMFO_00025 1.1e-54 abrB K COG2002 Regulators of stationary sporulation gene expression
MHFBIMFO_00026 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHFBIMFO_00027 8e-148 tatD L hydrolase, TatD
MHFBIMFO_00028 5e-105 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHFBIMFO_00029 2.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHFBIMFO_00030 5.8e-163 yabG S peptidase
MHFBIMFO_00031 2.4e-37 veg S protein conserved in bacteria
MHFBIMFO_00032 1.9e-26 sspF S DNA topological change
MHFBIMFO_00033 7.3e-158 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHFBIMFO_00034 1.3e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MHFBIMFO_00035 1.2e-61 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MHFBIMFO_00036 6.1e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MHFBIMFO_00037 6.2e-244 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHFBIMFO_00038 5.6e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHFBIMFO_00039 2e-112 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHFBIMFO_00040 5.4e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHFBIMFO_00041 5.7e-38 yabK S Peptide ABC transporter permease
MHFBIMFO_00042 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHFBIMFO_00043 2.1e-91 spoVT K stage V sporulation protein
MHFBIMFO_00044 1.3e-277 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHFBIMFO_00045 2.8e-191 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MHFBIMFO_00046 2.4e-41 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MHFBIMFO_00047 3e-50 yabP S Sporulation protein YabP
MHFBIMFO_00048 1.4e-105 yabQ S spore cortex biosynthesis protein
MHFBIMFO_00049 1.9e-60 divIC D Septum formation initiator
MHFBIMFO_00050 4.8e-54 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MHFBIMFO_00052 8e-148 L PFAM transposase IS4 family protein
MHFBIMFO_00053 1.7e-82 L PFAM transposase IS4 family protein
MHFBIMFO_00054 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MHFBIMFO_00055 8.7e-120 yabS S protein containing a von Willebrand factor type A (vWA) domain
MHFBIMFO_00056 2.8e-166 KLT serine threonine protein kinase
MHFBIMFO_00057 4e-278 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHFBIMFO_00058 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MHFBIMFO_00059 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHFBIMFO_00060 1.7e-159 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MHFBIMFO_00061 1.3e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHFBIMFO_00062 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MHFBIMFO_00063 3.4e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MHFBIMFO_00064 3.2e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHFBIMFO_00065 1.1e-97 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MHFBIMFO_00067 5.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MHFBIMFO_00068 4.3e-42 S COG NOG14552 non supervised orthologous group
MHFBIMFO_00069 5.3e-43
MHFBIMFO_00070 1.3e-181 yaaC S YaaC-like Protein
MHFBIMFO_00071 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MHFBIMFO_00072 6.5e-251 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MHFBIMFO_00073 1.6e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MHFBIMFO_00074 1.3e-102 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MHFBIMFO_00075 3.4e-212 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHFBIMFO_00076 6.5e-09
MHFBIMFO_00077 3.3e-126 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MHFBIMFO_00078 2.9e-119 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MHFBIMFO_00079 2.2e-251 yaaH M Glycoside Hydrolase Family
MHFBIMFO_00080 5e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHFBIMFO_00081 5.3e-306 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHFBIMFO_00082 1.3e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHFBIMFO_00083 1.5e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHFBIMFO_00084 3.4e-08 yaaL S Protein of unknown function (DUF2508)
MHFBIMFO_00085 4.8e-36 bofA S Sigma-K factor-processing regulatory protein BofA
MHFBIMFO_00086 1.1e-15 S Ribbon-helix-helix protein, copG family
MHFBIMFO_00087 2.3e-212 L Transposase
MHFBIMFO_00088 4.3e-42 S COG NOG14552 non supervised orthologous group
MHFBIMFO_00089 5.3e-43
MHFBIMFO_00090 5.4e-75 ctsR K Belongs to the CtsR family
MHFBIMFO_00091 1.3e-99 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MHFBIMFO_00092 1.9e-192 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MHFBIMFO_00093 0.0 clpC O Belongs to the ClpA ClpB family
MHFBIMFO_00094 1.1e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHFBIMFO_00095 6.9e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MHFBIMFO_00096 7.5e-118 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHFBIMFO_00097 2.1e-82 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MHFBIMFO_00098 1.9e-283 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHFBIMFO_00099 7.7e-115 cysE 2.3.1.30 E Serine acetyltransferase
MHFBIMFO_00100 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHFBIMFO_00101 3e-69 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHFBIMFO_00102 1.3e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHFBIMFO_00103 8.7e-90 yacP S RNA-binding protein containing a PIN domain
MHFBIMFO_00104 1.2e-109 sigH K Belongs to the sigma-70 factor family
MHFBIMFO_00105 6.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHFBIMFO_00106 9.2e-95 nusG K Participates in transcription elongation, termination and antitermination
MHFBIMFO_00107 1.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHFBIMFO_00108 3.5e-126 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHFBIMFO_00109 8e-09 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHFBIMFO_00110 5.4e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHFBIMFO_00111 1.7e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHFBIMFO_00112 6.5e-113 rsmC 2.1.1.172 J Methyltransferase
MHFBIMFO_00113 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHFBIMFO_00114 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHFBIMFO_00115 1.2e-36 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
MHFBIMFO_00116 3.3e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHFBIMFO_00117 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHFBIMFO_00118 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHFBIMFO_00119 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHFBIMFO_00120 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MHFBIMFO_00121 2.6e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHFBIMFO_00122 1.1e-107 rplD J Forms part of the polypeptide exit tunnel
MHFBIMFO_00123 1.8e-41 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHFBIMFO_00124 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHFBIMFO_00125 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHFBIMFO_00126 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHFBIMFO_00127 1.4e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHFBIMFO_00128 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHFBIMFO_00129 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
MHFBIMFO_00130 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHFBIMFO_00131 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHFBIMFO_00132 9.6e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHFBIMFO_00133 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHFBIMFO_00134 5.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHFBIMFO_00135 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHFBIMFO_00136 3.9e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHFBIMFO_00137 4.7e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHFBIMFO_00138 6.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHFBIMFO_00139 4.1e-23 rpmD J Ribosomal protein L30
MHFBIMFO_00140 1.2e-71 rplO J binds to the 23S rRNA
MHFBIMFO_00141 6.9e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHFBIMFO_00142 9.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHFBIMFO_00143 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHFBIMFO_00144 1.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHFBIMFO_00145 5.2e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHFBIMFO_00146 5.8e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHFBIMFO_00147 5.8e-65 rplQ J Ribosomal protein L17
MHFBIMFO_00148 3.7e-157 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHFBIMFO_00149 2.2e-162 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHFBIMFO_00150 2.7e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHFBIMFO_00151 1.4e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHFBIMFO_00152 3.8e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHFBIMFO_00153 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MHFBIMFO_00154 1.9e-09 S Protein conserved in bacteria
MHFBIMFO_00155 2.6e-227 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MHFBIMFO_00156 9.3e-115 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MHFBIMFO_00157 6.8e-273 lysP E amino acid
MHFBIMFO_00158 5.7e-82 ybaK S Protein of unknown function (DUF2521)
MHFBIMFO_00159 6.2e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHFBIMFO_00160 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MHFBIMFO_00161 1.4e-61 gerD S Spore gernimation protein
MHFBIMFO_00162 2.3e-100 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MHFBIMFO_00163 5.5e-214 L Transposase
MHFBIMFO_00164 8.2e-64 L Transposase IS200 like
MHFBIMFO_00165 1.4e-211 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
MHFBIMFO_00166 5.3e-175 K Transcriptional regulator
MHFBIMFO_00167 5.5e-138 pdaB 3.5.1.104 G xylanase chitin deacetylase
MHFBIMFO_00168 1.2e-30
MHFBIMFO_00169 2e-258 cydA 1.10.3.14 C oxidase, subunit
MHFBIMFO_00170 2.2e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MHFBIMFO_00171 0.0 cydD V ATP-binding
MHFBIMFO_00172 0.0 cydD V ATP-binding protein
MHFBIMFO_00173 3e-248 L PFAM Transposase, IS4-like
MHFBIMFO_00174 4.3e-42 S COG NOG14552 non supervised orthologous group
MHFBIMFO_00175 5.3e-43
MHFBIMFO_00185 1.1e-169 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MHFBIMFO_00187 3.2e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MHFBIMFO_00188 9.8e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MHFBIMFO_00189 5.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHFBIMFO_00190 1.8e-221 ybbR S protein conserved in bacteria
MHFBIMFO_00191 5.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHFBIMFO_00192 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHFBIMFO_00194 7.9e-99 M1-431 S Protein of unknown function (DUF1706)
MHFBIMFO_00195 2.8e-145 3.1.2.21 I Acyl-ACP thioesterase
MHFBIMFO_00197 1.5e-217 EGP Major facilitator Superfamily
MHFBIMFO_00198 7.5e-203 EGP Major facilitator Superfamily
MHFBIMFO_00199 1.6e-152 K Bacterial regulatory helix-turn-helix protein, lysR family
MHFBIMFO_00200 6.4e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MHFBIMFO_00201 1.2e-249 NT Chemoreceptor zinc-binding domain
MHFBIMFO_00202 3.9e-127 S Putative adhesin
MHFBIMFO_00203 2.3e-96 S Protein of unknown function (DUF1700)
MHFBIMFO_00204 6.9e-53 K PadR family transcriptional regulator
MHFBIMFO_00205 7.7e-191 NT chemotaxis protein
MHFBIMFO_00206 3.7e-89 L Transposase, IS4 family protein
MHFBIMFO_00207 3.6e-48 ykvR S Protein of unknown function (DUF3219)
MHFBIMFO_00208 2.4e-173 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHFBIMFO_00211 4.6e-81 V CAAX protease self-immunity
MHFBIMFO_00212 6.2e-238 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 I Hydroxymethylglutaryl-coenzyme A reductase
MHFBIMFO_00213 1.1e-222 mvaS 2.3.3.10 I synthase
MHFBIMFO_00214 6.3e-213 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
MHFBIMFO_00215 5e-54 S DsrE/DsrF-like family
MHFBIMFO_00216 6.1e-33
MHFBIMFO_00217 5.1e-176 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHFBIMFO_00218 6.7e-181 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHFBIMFO_00219 1.4e-268 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
MHFBIMFO_00220 2.5e-83 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MHFBIMFO_00221 5.9e-266 treP 2.7.1.201, 2.7.1.211 G phosphotransferase system
MHFBIMFO_00222 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MHFBIMFO_00223 7.4e-132 treR K transcriptional
MHFBIMFO_00224 1.7e-230 EG COG2610 H gluconate symporter and related permeases
MHFBIMFO_00225 4.3e-310 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MHFBIMFO_00226 1e-125 gntR K transcriptional
MHFBIMFO_00227 7.2e-173 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MHFBIMFO_00228 7.7e-82 fld C Flavodoxin
MHFBIMFO_00229 2.2e-204 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHFBIMFO_00230 1.5e-138 4.1.99.16, 4.2.3.22, 4.2.3.75 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MHFBIMFO_00232 0.0 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MHFBIMFO_00233 4.3e-30 P Heavy-metal-associated domain
MHFBIMFO_00236 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHFBIMFO_00237 5.6e-88 fld C Flavodoxin
MHFBIMFO_00238 4.9e-193 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHFBIMFO_00239 7.3e-104 plsY 2.3.1.15 I Belongs to the PlsY family
MHFBIMFO_00240 6.6e-209 crtQ M Glycosyl transferase family 21
MHFBIMFO_00241 4.3e-21 S transposase or invertase
MHFBIMFO_00243 2.1e-93 Q Thioesterase superfamily
MHFBIMFO_00244 2.2e-48 sugE P Multidrug resistance protein
MHFBIMFO_00245 1.1e-53 ykkC P Multidrug resistance protein
MHFBIMFO_00246 2e-138 yfcA S membrane transporter protein
MHFBIMFO_00247 1.1e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHFBIMFO_00248 1.5e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHFBIMFO_00249 2.4e-178 fhuD P Periplasmic binding protein
MHFBIMFO_00250 1.6e-151 fhuC 3.6.3.34 HP ABC transporter
MHFBIMFO_00251 9.1e-200 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MHFBIMFO_00252 5.8e-19
MHFBIMFO_00253 3.1e-116
MHFBIMFO_00254 7.2e-98
MHFBIMFO_00255 5.2e-117 yeeN K transcriptional regulatory protein
MHFBIMFO_00256 1.2e-188 T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
MHFBIMFO_00257 4.9e-50 L Transposase
MHFBIMFO_00258 1.4e-270 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHFBIMFO_00260 3.5e-282 yobO M Pectate lyase superfamily protein
MHFBIMFO_00261 1.6e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MHFBIMFO_00262 2.3e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MHFBIMFO_00263 5.7e-135 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MHFBIMFO_00264 2.6e-112 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MHFBIMFO_00265 1.2e-97 ywhH S Aminoacyl-tRNA editing domain
MHFBIMFO_00266 2.7e-205 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
MHFBIMFO_00267 0.0 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHFBIMFO_00268 2.1e-191 2.7.7.65 T Diguanylate cyclase, GGDEF domain
MHFBIMFO_00270 2.6e-169 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHFBIMFO_00271 9.2e-180 S Nuclease-related domain
MHFBIMFO_00272 6.7e-92
MHFBIMFO_00273 2.3e-173 czcD P COG1230 Co Zn Cd efflux system component
MHFBIMFO_00274 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHFBIMFO_00275 1.9e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases C terminal
MHFBIMFO_00276 6.9e-181 mvaD 4.1.1.33 I GHMP kinases N terminal domain
MHFBIMFO_00277 6.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases C terminal
MHFBIMFO_00279 2.6e-112 yhfK GM NmrA-like family
MHFBIMFO_00280 4.1e-43 K Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MHFBIMFO_00281 3.1e-179 KT Sigma-54 interaction domain
MHFBIMFO_00282 8.4e-234 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MHFBIMFO_00283 2.2e-111 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHFBIMFO_00284 2.3e-38 gcvR T Belongs to the UPF0237 family
MHFBIMFO_00285 4.8e-249 XK27_08635 S UPF0210 protein
MHFBIMFO_00286 2.8e-94 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
MHFBIMFO_00287 4e-84 cotF M Spore coat protein
MHFBIMFO_00288 1.1e-175 iolS C Aldo keto reductase
MHFBIMFO_00289 3.8e-99 ydjA C Nitroreductase family
MHFBIMFO_00290 3.2e-253 E COG1113 Gamma-aminobutyrate permease and related permeases
MHFBIMFO_00291 4.3e-275 dtpT E amino acid peptide transporter
MHFBIMFO_00292 5.8e-280 lysP E amino acid
MHFBIMFO_00293 4.3e-98 puuR K Cupin domain
MHFBIMFO_00294 2.5e-211 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHFBIMFO_00295 9.6e-141 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
MHFBIMFO_00296 4.1e-139 potC E COG1177 ABC-type spermidine putrescine transport system, permease component II
MHFBIMFO_00297 5.8e-205 potD E COG0687 Spermidine putrescine-binding periplasmic protein
MHFBIMFO_00299 1.5e-250 H HemY protein
MHFBIMFO_00300 3.7e-252 E amino acid
MHFBIMFO_00301 2.7e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHFBIMFO_00302 3e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MHFBIMFO_00303 2.5e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHFBIMFO_00304 6.9e-251 E Amino acid permease
MHFBIMFO_00305 2.7e-224 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MHFBIMFO_00306 1.2e-233 amt P Ammonium transporter
MHFBIMFO_00307 1e-298 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MHFBIMFO_00308 4.6e-123 citT T response regulator
MHFBIMFO_00309 1.2e-247 citH C Citrate transporter
MHFBIMFO_00310 1.4e-181 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MHFBIMFO_00311 0.0 helD 3.6.4.12 L DNA helicase
MHFBIMFO_00313 2.2e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MHFBIMFO_00314 5e-153 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MHFBIMFO_00315 3.9e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHFBIMFO_00316 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MHFBIMFO_00317 3.7e-211 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHFBIMFO_00318 1.9e-121 K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MHFBIMFO_00321 2.5e-132 ric D Di-iron-containing protein involved in the repair of iron-sulfur clusters
MHFBIMFO_00322 6.4e-96 S Belongs to the UPF0312 family
MHFBIMFO_00323 7.6e-216 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MHFBIMFO_00325 3.9e-195 T HD domain
MHFBIMFO_00326 1.2e-279 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MHFBIMFO_00327 0.0 ydaO E amino acid
MHFBIMFO_00328 1.6e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHFBIMFO_00329 3e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHFBIMFO_00330 7.7e-175 ydbI S AI-2E family transporter
MHFBIMFO_00331 3.4e-132 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHFBIMFO_00332 1.2e-135 glnH ET Belongs to the bacterial solute-binding protein 3 family
MHFBIMFO_00333 1.4e-108 gluC P ABC transporter
MHFBIMFO_00334 1e-117 glnP P ABC transporter
MHFBIMFO_00335 2.6e-70 K helix_turn_helix gluconate operon transcriptional repressor
MHFBIMFO_00336 2.2e-196 S Protein of unknown function (DUF1648)
MHFBIMFO_00337 2.4e-53 yodB K transcriptional
MHFBIMFO_00338 3.5e-233 S SNARE associated Golgi protein
MHFBIMFO_00339 5.3e-99 yngC S membrane-associated protein
MHFBIMFO_00340 2.5e-159 msrR K COG1316 Transcriptional regulator
MHFBIMFO_00342 1.8e-113 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E MeTHIonine synthase
MHFBIMFO_00343 1.3e-221 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MHFBIMFO_00344 0.0 metH 2.1.1.13 E Methionine synthase
MHFBIMFO_00345 1.6e-09 csbD S Belongs to the UPF0337 (CsbD) family
MHFBIMFO_00346 5.1e-89 K ComK protein
MHFBIMFO_00347 2.4e-96 sigS 2.7.7.6 K Belongs to the sigma-70 factor family. ECF subfamily
MHFBIMFO_00348 3.9e-153 E lipolytic protein G-D-S-L family
MHFBIMFO_00349 4.9e-123 ywqC M biosynthesis protein
MHFBIMFO_00350 9.1e-111 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MHFBIMFO_00351 1.9e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MHFBIMFO_00352 5.3e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MHFBIMFO_00353 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MHFBIMFO_00354 3e-81 pglC M Bacterial sugar transferase
MHFBIMFO_00355 1.5e-163 wbpV 5.1.3.2 GM NAD-dependent epimerase
MHFBIMFO_00356 9.4e-211 2.4.1.52 GT4 M Glycosyl transferase 4-like
MHFBIMFO_00357 1.4e-212 cps4G M Glycosyl transferases group 1
MHFBIMFO_00358 2.1e-211
MHFBIMFO_00359 2.8e-168 rgpB GT2 S Glycosyl transferase family 2
MHFBIMFO_00360 1.3e-198 wbnF 5.1.3.6 M NAD-dependent epimerase dehydratase
MHFBIMFO_00361 6.3e-57 L Transposase, IS4 family protein
MHFBIMFO_00362 5.2e-08 L Transposase, IS4 family protein
MHFBIMFO_00364 0.0 L Domain of unknown function (DUF4277)
MHFBIMFO_00365 1.7e-249 S polysaccharide biosynthetic process
MHFBIMFO_00366 4e-164 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHFBIMFO_00367 7.7e-84 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MHFBIMFO_00368 6.2e-162 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHFBIMFO_00369 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHFBIMFO_00370 1.7e-259 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHFBIMFO_00372 8.7e-107 L COG3436 Transposase and inactivated derivatives
MHFBIMFO_00373 4.2e-46 L COG3436 Transposase and inactivated derivatives
MHFBIMFO_00374 1e-223 L Transposase
MHFBIMFO_00375 8.2e-226 V HNH endonuclease
MHFBIMFO_00376 1.5e-37
MHFBIMFO_00377 3.1e-217
MHFBIMFO_00378 2.1e-216 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHFBIMFO_00379 5.8e-11 L Transposase, IS4 family protein
MHFBIMFO_00381 7.3e-291 xylB 2.7.1.12, 2.7.1.17 G xylulose kinase
MHFBIMFO_00382 0.0 M Peptidase M30
MHFBIMFO_00383 3.2e-59 croE S Helix-turn-helix
MHFBIMFO_00384 3.5e-135 E IrrE N-terminal-like domain
MHFBIMFO_00385 2.8e-24
MHFBIMFO_00386 4.8e-249 yicJ G MFS/sugar transport protein
MHFBIMFO_00387 4.4e-307 2.7.1.12, 2.7.1.17 G xylulose kinase
MHFBIMFO_00388 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHFBIMFO_00389 5.3e-217 2.7.1.2 GK ROK family
MHFBIMFO_00390 2.2e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHFBIMFO_00391 2.3e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHFBIMFO_00392 1e-181 3.1.1.5 I Alpha beta hydrolase
MHFBIMFO_00395 0.0 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHFBIMFO_00396 2.8e-180 3.2.1.96 M cysteine-type peptidase activity
MHFBIMFO_00398 1.9e-29 yodI
MHFBIMFO_00399 3.2e-152 yjaZ O Zn-dependent protease
MHFBIMFO_00400 3.5e-80 yodH Q Methyltransferase
MHFBIMFO_00401 0.0 gtfC 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
MHFBIMFO_00402 2.1e-162 S HipA-like C-terminal domain
MHFBIMFO_00403 1.6e-145 S HIRAN domain
MHFBIMFO_00404 6e-67 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
MHFBIMFO_00405 3.7e-182 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHFBIMFO_00406 6.6e-65 yjbR S YjbR
MHFBIMFO_00407 1.2e-64 S Protein of unknown function (DUF1648)
MHFBIMFO_00408 2.5e-250 L Metallo-beta-lactamase superfamily
MHFBIMFO_00409 1.4e-30 S Protein of unknown function (DUF3006)
MHFBIMFO_00410 0.0 ganB 3.2.1.89 G arabinogalactan
MHFBIMFO_00411 8e-221 csd1 S CRISPR-associated protein, Csd1 family
MHFBIMFO_00412 4.7e-19 csd2 L CRISPR-associated protein Cas7
MHFBIMFO_00413 0.0 ybeC E amino acid
MHFBIMFO_00414 1.4e-173 K cell envelope-related transcriptional attenuator
MHFBIMFO_00416 2.8e-50
MHFBIMFO_00417 1.3e-173 ydhF S Oxidoreductase
MHFBIMFO_00418 3e-154 S transposase or invertase
MHFBIMFO_00419 3.1e-11 S transposase or invertase
MHFBIMFO_00420 2.2e-34 C acyl-CoA transferases carnitine dehydratase
MHFBIMFO_00421 6.5e-182 yfmJ S N-terminal domain of oxidoreductase
MHFBIMFO_00422 1.1e-15 S Ribbon-helix-helix protein, copG family
MHFBIMFO_00423 1.2e-210 L Transposase
MHFBIMFO_00424 8.1e-216 EGP Major facilitator Superfamily
MHFBIMFO_00425 0.0 2.7.1.202 K transcriptional regulator, MtlR
MHFBIMFO_00426 9.3e-53 licB 2.7.1.196, 2.7.1.205 G phosphotransferase system
MHFBIMFO_00427 1.2e-52 chbA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MHFBIMFO_00428 4.6e-210 S Bacterial protein of unknown function (DUF871)
MHFBIMFO_00429 6.4e-235 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFBIMFO_00430 7.2e-256 gph G MFS/sugar transport protein
MHFBIMFO_00432 3e-65 E Amino acid permease
MHFBIMFO_00433 2.8e-142 K helix_turn_helix, arabinose operon control protein
MHFBIMFO_00434 5.3e-133 G Glycosyl hydrolases family 39
MHFBIMFO_00435 1.8e-11 ydjE EGP Major facilitator superfamily
MHFBIMFO_00436 1.7e-194 ydjE EGP Major facilitator superfamily
MHFBIMFO_00437 1.4e-74 K transcriptional
MHFBIMFO_00438 1.3e-210 EGP Major facilitator Superfamily
MHFBIMFO_00439 5.9e-180 K Transcriptional regulator
MHFBIMFO_00440 0.0 bga2 3.2.1.23 G beta-galactosidase
MHFBIMFO_00442 4e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHFBIMFO_00443 3.5e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHFBIMFO_00444 2.6e-115 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MHFBIMFO_00445 2.6e-211 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHFBIMFO_00446 4.5e-97 yvbF K Belongs to the GbsR family
MHFBIMFO_00447 1.6e-97 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
MHFBIMFO_00448 9.4e-147 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFBIMFO_00449 3.3e-211 L Transposase
MHFBIMFO_00450 1e-27 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFBIMFO_00451 3.2e-46
MHFBIMFO_00452 2.6e-111 yjlB S Cupin domain
MHFBIMFO_00453 1.4e-150 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
MHFBIMFO_00454 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
MHFBIMFO_00455 5.9e-137 yflN_1 S Metallo-beta-lactamase superfamily
MHFBIMFO_00456 2.9e-53 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MHFBIMFO_00457 4.7e-304 comM O Mg chelatase subunit ChlI
MHFBIMFO_00458 4.1e-149 S transposase or invertase
MHFBIMFO_00459 4.6e-21
MHFBIMFO_00460 2.7e-202 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
MHFBIMFO_00461 5.5e-211 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MHFBIMFO_00462 2e-160 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MHFBIMFO_00463 6.6e-306 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MHFBIMFO_00464 2.8e-210 nifS 2.8.1.7 E Cysteine desulfurase
MHFBIMFO_00465 2.6e-89 S NYN domain
MHFBIMFO_00466 7.1e-144 focA P Formate nitrite
MHFBIMFO_00467 1.9e-150 cbiQ P COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
MHFBIMFO_00468 0.0 ykoD P ABC transporter, ATP-binding protein
MHFBIMFO_00469 6.8e-93 S UPF0397 protein
MHFBIMFO_00470 1.5e-163 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
MHFBIMFO_00471 5.2e-123 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MHFBIMFO_00472 8.9e-254 EG COG2610 H gluconate symporter and related permeases
MHFBIMFO_00473 5e-284 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHFBIMFO_00474 1.7e-221 adhB 1.1.1.1, 1.1.1.202 C alcohol dehydrogenase
MHFBIMFO_00475 0.0 KT Transcriptional regulator
MHFBIMFO_00476 2.8e-60 xylS 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MHFBIMFO_00477 0.0 Otg1 S Predicted membrane protein (DUF2339)
MHFBIMFO_00478 2e-52
MHFBIMFO_00480 7.5e-152 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
MHFBIMFO_00481 1.6e-25 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MHFBIMFO_00482 1.6e-196 S Metallo-beta-lactamase superfamily
MHFBIMFO_00483 8.2e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MHFBIMFO_00484 2.3e-134 phnE 3.6.1.63 P ABC transporter
MHFBIMFO_00485 6.1e-143 phnE 3.6.1.63 P ABC transporter
MHFBIMFO_00486 1.1e-175 phnD P Phosphonate ABC transporter
MHFBIMFO_00487 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MHFBIMFO_00488 2.1e-207 ysdC G COG1363 Cellulase M and related proteins
MHFBIMFO_00489 3e-12 S double-stranded DNA endodeoxyribonuclease activity
MHFBIMFO_00490 2.1e-299 yvfH C L-lactate permease
MHFBIMFO_00491 1.8e-122 yvfI K COG2186 Transcriptional regulators
MHFBIMFO_00492 2.7e-232 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHFBIMFO_00493 7e-62
MHFBIMFO_00495 7.4e-169 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MHFBIMFO_00496 1.3e-205 EGP Major facilitator Superfamily
MHFBIMFO_00497 3.7e-204 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MHFBIMFO_00499 2.2e-16 S YvrJ protein family
MHFBIMFO_00500 9.8e-11 S Protein of unknown function (DUF2922)
MHFBIMFO_00501 2.6e-11 S Protein of unknown function (DUF1659)
MHFBIMFO_00502 0.0 O Belongs to the peptidase S8 family
MHFBIMFO_00503 6.6e-69 S Protein of unknown function (DUF2512)
MHFBIMFO_00504 3.1e-52 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MHFBIMFO_00505 6.9e-53 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
MHFBIMFO_00506 2.5e-78
MHFBIMFO_00507 2.2e-249 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHFBIMFO_00508 9.8e-293 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHFBIMFO_00509 0.0 2.7.1.202 K transcriptional regulator, MtlR
MHFBIMFO_00510 1e-156 kdsA 2.5.1.55 M Belongs to the KdsA family
MHFBIMFO_00511 7.9e-177 kdsD 5.3.1.13 M Belongs to the SIS family. GutQ KpsF subfamily
MHFBIMFO_00512 5e-226 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHFBIMFO_00513 1.4e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHFBIMFO_00515 0.0 treP 2.4.1.64 GH65 G Glycoside hydrolase, family 65
MHFBIMFO_00516 1.1e-147 G Binding-protein-dependent transport system inner membrane component
MHFBIMFO_00517 1e-221 sugA G Binding-protein-dependent transport system inner membrane component
MHFBIMFO_00518 8.7e-229 G Bacterial extracellular solute-binding protein
MHFBIMFO_00519 1.4e-133 K helix_turn_helix, arabinose operon control protein
MHFBIMFO_00520 1.8e-138 gumM 2.4.1.187, 2.4.1.252 GT26,GT4 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHFBIMFO_00521 7e-52 S Iron-sulphur cluster biosynthesis
MHFBIMFO_00522 1.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
MHFBIMFO_00523 4.6e-160 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHFBIMFO_00524 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MHFBIMFO_00525 4.4e-75 3.4.21.121 O Belongs to the peptidase S8 family
MHFBIMFO_00526 6.1e-85
MHFBIMFO_00527 4.1e-147 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MHFBIMFO_00528 5.3e-133 IQ Short-chain dehydrogenase reductase sdr
MHFBIMFO_00529 5.5e-30 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MHFBIMFO_00530 3e-110 cyoC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MHFBIMFO_00531 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHFBIMFO_00532 1.2e-153 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MHFBIMFO_00533 1.4e-124 yhcW 5.4.2.6 S hydrolase
MHFBIMFO_00534 5.3e-167 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MHFBIMFO_00535 1.4e-74 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MHFBIMFO_00536 6.6e-133 L Integrase core domain
MHFBIMFO_00537 1.3e-125 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MHFBIMFO_00538 0.0 mapA 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MHFBIMFO_00539 4.4e-261 G Major facilitator Superfamily
MHFBIMFO_00540 1.7e-187 malR K Transcriptional regulator
MHFBIMFO_00541 7.3e-81 T PhoQ Sensor
MHFBIMFO_00542 3.5e-132 T PhoQ Sensor
MHFBIMFO_00543 9e-20
MHFBIMFO_00544 0.0 ppc 4.1.1.31 C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MHFBIMFO_00545 9.9e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MHFBIMFO_00546 4.8e-75 yabE S 3D domain
MHFBIMFO_00547 2.4e-98 relA_2 2.7.6.5, 3.1.7.2 KT HD domain
MHFBIMFO_00548 0.0 pip S YhgE Pip N-terminal domain protein
MHFBIMFO_00549 2.9e-48 yqgV S Thiamine-binding protein
MHFBIMFO_00550 1.5e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
MHFBIMFO_00551 0.0 S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHFBIMFO_00552 0.0 levR K PTS system fructose IIA component
MHFBIMFO_00553 1.1e-84 manX 2.7.1.191 G PTS system sorbose subfamily IIB component
MHFBIMFO_00554 1.1e-178 manL 2.7.1.191 G PTS system mannose fructose sorbose family
MHFBIMFO_00555 1.5e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MHFBIMFO_00556 1.9e-169 manN G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MHFBIMFO_00557 1.2e-64 manO S Domain of unknown function (DUF956)
MHFBIMFO_00558 7.8e-213 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MHFBIMFO_00559 8.2e-279 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MHFBIMFO_00560 6.6e-165 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MHFBIMFO_00561 2.7e-85 S Heat induced stress protein YflT
MHFBIMFO_00562 6.6e-268 nylA 3.5.1.4 J Belongs to the amidase family
MHFBIMFO_00563 3.2e-15 S Ribbon-helix-helix protein, copG family
MHFBIMFO_00564 2.5e-211 L Transposase
MHFBIMFO_00565 4.5e-52 M1-594 S Thiamine-binding protein
MHFBIMFO_00566 2.1e-140 ssuC_1 P binding-protein-dependent transport systems inner membrane component
MHFBIMFO_00567 6.2e-185 M1-596 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHFBIMFO_00568 1.6e-140 P ABC transporter, ATP-binding protein
MHFBIMFO_00569 5.2e-162 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHFBIMFO_00570 5.2e-190 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MHFBIMFO_00571 4.9e-243 hom 1.1.1.3 E homoserine dehydrogenase
MHFBIMFO_00572 4.2e-149 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MHFBIMFO_00573 5.1e-16 S Protein of unknown function (DUF4064)
MHFBIMFO_00574 6.4e-287 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHFBIMFO_00575 5.7e-166 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MHFBIMFO_00576 9.6e-48 yhdT S Sodium pantothenate symporter
MHFBIMFO_00577 1.7e-236 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHFBIMFO_00580 1.3e-171 corA P Mg2 transporter protein CorA family protein
MHFBIMFO_00581 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MHFBIMFO_00582 7.9e-197 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MHFBIMFO_00583 2.3e-79
MHFBIMFO_00584 3.6e-76 lytE CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHFBIMFO_00585 5e-139 map 3.4.11.18 E Methionine aminopeptidase
MHFBIMFO_00586 7.9e-100 bioY S Biotin biosynthesis protein
MHFBIMFO_00587 1.7e-190 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHFBIMFO_00588 1.6e-146 aacC 2.3.1.81 V aminoglycoside
MHFBIMFO_00589 6.9e-224 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHFBIMFO_00590 9.6e-71 yxiE T Belongs to the universal stress protein A family
MHFBIMFO_00591 3.1e-27
MHFBIMFO_00592 3.4e-81
MHFBIMFO_00593 3e-228 yfkA S YfkB-like domain
MHFBIMFO_00594 4.1e-72 gutA G MFS/sugar transport protein
MHFBIMFO_00595 6.4e-176 ykvZ 5.1.1.1 K Transcriptional regulator
MHFBIMFO_00596 3.6e-94 hxlB 4.1.2.43, 5.3.1.27 M arabinose-5-phosphate isomerase activity
MHFBIMFO_00597 1.8e-147 ykrA S hydrolases of the HAD superfamily
MHFBIMFO_00599 2.3e-147 yvaK 3.1.1.1 S BAAT / Acyl-CoA thioester hydrolase C terminal
MHFBIMFO_00600 9e-19 M Spore coat protein
MHFBIMFO_00601 7.7e-140 I alpha/beta hydrolase fold
MHFBIMFO_00602 2.4e-158 S Aldo/keto reductase family
MHFBIMFO_00604 2.5e-98 1.5.1.38 S FMN reductase
MHFBIMFO_00605 3.3e-32 K sequence-specific DNA binding
MHFBIMFO_00606 5.9e-249 yhaO L Calcineurin-like phosphoesterase superfamily domain
MHFBIMFO_00607 0.0 L AAA domain
MHFBIMFO_00608 1.2e-160 mmgB 1.1.1.157 I Dehydrogenase
MHFBIMFO_00609 2.7e-247 yeeO V Mate efflux family protein
MHFBIMFO_00611 1.3e-09 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MHFBIMFO_00612 5.7e-112 yhbD K Protein of unknown function (DUF4004)
MHFBIMFO_00613 2e-227 yhdR 2.6.1.1 E Aminotransferase
MHFBIMFO_00614 9e-110 proA_2 H Methyltransferase
MHFBIMFO_00615 0.0 rafA 3.2.1.22 G Alpha-galactosidase
MHFBIMFO_00616 1e-51 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHFBIMFO_00617 8.1e-276 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHFBIMFO_00619 2.4e-71 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
MHFBIMFO_00620 8e-191 arsB P Arsenic resistance protein
MHFBIMFO_00621 1.2e-97 padR K Domain of unknown function (DUF2703)
MHFBIMFO_00622 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
MHFBIMFO_00623 1.6e-63 arsD S Arsenical resistance operon trans-acting repressor ArsD
MHFBIMFO_00624 3.3e-58 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
MHFBIMFO_00625 8.9e-33 L COG2963 Transposase and inactivated derivatives
MHFBIMFO_00626 2.4e-71 L COG2801 Transposase and inactivated derivatives
MHFBIMFO_00627 2.9e-72 L COG2801 Transposase and inactivated derivatives
MHFBIMFO_00628 3.5e-249 S Protein of unknown function DUF262
MHFBIMFO_00629 0.0 S Protein of unknown function (DUF1524)
MHFBIMFO_00630 8.8e-147 ubiE Q Methyltransferase type 11
MHFBIMFO_00631 9.4e-211 M Glycosyl hydrolases family 25
MHFBIMFO_00633 6e-171 yfhF S nucleoside-diphosphate sugar epimerase
MHFBIMFO_00634 1.8e-158 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHFBIMFO_00635 1.2e-57 thiW S Thiamine-precursor transporter protein (ThiW)
MHFBIMFO_00636 1.8e-13 yjhE S Phage tail protein
MHFBIMFO_00637 7.4e-248 L Transposase, IS4 family protein
MHFBIMFO_00638 1.2e-148 hel M 5'-nucleotidase, lipoprotein e(P4)
MHFBIMFO_00641 1.4e-214 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MHFBIMFO_00642 8.5e-36 K ArsR family transcriptional regulator
MHFBIMFO_00643 6.5e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHFBIMFO_00644 3.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MHFBIMFO_00645 2e-280 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MHFBIMFO_00646 6.4e-201 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
MHFBIMFO_00647 1.3e-182 K Transcriptional regulator
MHFBIMFO_00649 5.1e-32 S Cold-inducible protein YdjO
MHFBIMFO_00650 1.5e-14
MHFBIMFO_00652 3.6e-165 cvfB S protein conserved in bacteria
MHFBIMFO_00653 2e-70 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHFBIMFO_00654 1.6e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
MHFBIMFO_00655 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MHFBIMFO_00656 7.3e-275 yusP P Major facilitator superfamily
MHFBIMFO_00657 2.2e-215 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHFBIMFO_00658 1.4e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHFBIMFO_00659 4.3e-124 gntR1 K transcriptional
MHFBIMFO_00660 3.2e-170 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MHFBIMFO_00661 2.2e-231 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MHFBIMFO_00662 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MHFBIMFO_00663 2.4e-168 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MHFBIMFO_00664 1.1e-115 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MHFBIMFO_00665 6e-208 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MHFBIMFO_00666 4.9e-125 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHFBIMFO_00667 7.5e-261 yfnA E amino acid
MHFBIMFO_00668 1.2e-154 degV S protein conserved in bacteria
MHFBIMFO_00669 7.8e-255 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MHFBIMFO_00670 2.1e-134 comFC S Phosphoribosyl transferase domain
MHFBIMFO_00671 4.4e-70 yvyF S flagellar protein
MHFBIMFO_00672 1e-38 flgM KNU Negative regulator of flagellin synthesis
MHFBIMFO_00673 7.6e-77 flgN NOU FlgN protein
MHFBIMFO_00674 1.1e-292 flgK N flagellar hook-associated protein
MHFBIMFO_00675 5.2e-159 flgL N Belongs to the bacterial flagellin family
MHFBIMFO_00676 2.2e-81 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MHFBIMFO_00677 1.7e-35 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MHFBIMFO_00678 1.6e-157 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MHFBIMFO_00680 0.0 ycbZ 3.4.21.53 O AAA domain
MHFBIMFO_00682 1.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MHFBIMFO_00684 2.7e-61 flaG N flagellar protein FlaG
MHFBIMFO_00685 0.0 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MHFBIMFO_00686 8.6e-69 fliS N flagellar protein FliS
MHFBIMFO_00687 3.9e-54 fliT S bacterial-type flagellum organization
MHFBIMFO_00688 1.6e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHFBIMFO_00689 5e-307 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MHFBIMFO_00690 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHFBIMFO_00691 3.2e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHFBIMFO_00692 4.2e-158 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MHFBIMFO_00693 5.5e-50 cccB C COG2010 Cytochrome c, mono- and diheme variants
MHFBIMFO_00696 7.1e-124 ftsE D cell division ATP-binding protein FtsE
MHFBIMFO_00697 1.4e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MHFBIMFO_00698 6.5e-97 D peptidase
MHFBIMFO_00699 2.4e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHFBIMFO_00700 9.3e-250 metY 2.5.1.49 E O-acetylhomoserine
MHFBIMFO_00701 3.3e-183 1.1.1.3 E homoserine dehydrogenase
MHFBIMFO_00702 1.2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MHFBIMFO_00703 3.1e-223 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHFBIMFO_00704 9.4e-167 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHFBIMFO_00705 8.8e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHFBIMFO_00706 5.6e-138 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MHFBIMFO_00707 1.7e-176 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MHFBIMFO_00708 2.8e-134
MHFBIMFO_00709 8.4e-32 S Family of unknown function (DUF5316)
MHFBIMFO_00710 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MHFBIMFO_00711 1.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHFBIMFO_00712 4.4e-67 S Family of unknown function (DUF5316)
MHFBIMFO_00713 2.3e-248 L PFAM Transposase_11
MHFBIMFO_00714 1.4e-40 fdxA C 4Fe-4S binding domain
MHFBIMFO_00715 9.3e-264 hemY2 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MHFBIMFO_00716 1.4e-12 L Transposase
MHFBIMFO_00717 1.2e-268 L Transposase
MHFBIMFO_00719 3.1e-246 L Transposase, IS4 family protein
MHFBIMFO_00720 6.1e-252 EGP Sugar (and other) transporter
MHFBIMFO_00721 1.3e-150 G myo-inosose-2 dehydratase activity
MHFBIMFO_00722 1e-156 araL 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHFBIMFO_00723 5.6e-116 sapB S MgtC SapB transporter
MHFBIMFO_00724 5.5e-98 K Glycerol-3-phosphate responsive antiterminator
MHFBIMFO_00725 2.5e-129 L Transposase IS4 family protein
MHFBIMFO_00726 2.8e-119 L Transposase IS4 family protein
MHFBIMFO_00727 1.9e-161 pstS P Phosphate
MHFBIMFO_00728 8.5e-160 pstC P probably responsible for the translocation of the substrate across the membrane
MHFBIMFO_00729 2.8e-157 pstA P Phosphate transport system permease
MHFBIMFO_00730 9.5e-155 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHFBIMFO_00731 8.9e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHFBIMFO_00732 2.7e-174 M Glycosyltransferase like family 2
MHFBIMFO_00733 0.0
MHFBIMFO_00734 5e-57 P EamA-like transporter family
MHFBIMFO_00735 1.5e-50 S EamA-like transporter family
MHFBIMFO_00736 1.4e-118 yfbR S HD containing hydrolase-like enzyme
MHFBIMFO_00737 5.4e-34 csbA S protein conserved in bacteria
MHFBIMFO_00738 2.1e-09 S Uncharacterized conserved protein (DUF2164)
MHFBIMFO_00739 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHFBIMFO_00740 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHFBIMFO_00741 2.8e-72 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MHFBIMFO_00742 6.1e-232 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHFBIMFO_00743 3.6e-232 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHFBIMFO_00744 4.5e-146 tagG GM Transport permease protein
MHFBIMFO_00745 0.0 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHFBIMFO_00746 2.5e-174 yvlB S Putative adhesin
MHFBIMFO_00747 1.4e-32 yvlD S Membrane
MHFBIMFO_00748 3.3e-172 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHFBIMFO_00749 9.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHFBIMFO_00750 1.7e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MHFBIMFO_00751 1.6e-72 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MHFBIMFO_00752 3.5e-256 S COG0457 FOG TPR repeat
MHFBIMFO_00753 3.1e-178 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHFBIMFO_00754 5.1e-86 yvcI 3.6.1.55 F Nudix hydrolase
MHFBIMFO_00755 1e-167 rapZ S Displays ATPase and GTPase activities
MHFBIMFO_00756 2.1e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MHFBIMFO_00757 4e-173 whiA K May be required for sporulation
MHFBIMFO_00758 4.3e-40 crh G Phosphocarrier protein Chr
MHFBIMFO_00759 8.3e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHFBIMFO_00761 4.5e-123 S transposase or invertase
MHFBIMFO_00762 1.9e-16 S transposase or invertase
MHFBIMFO_00763 1.2e-17 S transposase or invertase
MHFBIMFO_00764 8.4e-265 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHFBIMFO_00765 3.4e-29 sspB S spore protein
MHFBIMFO_00766 6.9e-206 msmK P Belongs to the ABC transporter superfamily
MHFBIMFO_00767 1e-170 lrp QT PucR C-terminal helix-turn-helix domain
MHFBIMFO_00768 3.3e-230 HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
MHFBIMFO_00769 1.7e-270 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MHFBIMFO_00771 1e-212 yheC HJ YheC/D like ATP-grasp
MHFBIMFO_00772 4e-264 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MHFBIMFO_00773 5.3e-209 yheB S Belongs to the UPF0754 family
MHFBIMFO_00774 6.1e-55 yheA S Belongs to the UPF0342 family
MHFBIMFO_00775 2.7e-160 yhaX S hydrolases of the HAD superfamily
MHFBIMFO_00776 2.1e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
MHFBIMFO_00777 1.7e-27 S YhzD-like protein
MHFBIMFO_00778 9.6e-122 P Integral membrane protein TerC family
MHFBIMFO_00779 4.7e-149 ycgR S permeases
MHFBIMFO_00780 6.1e-69 ycgQ S membrane
MHFBIMFO_00781 2e-249 yhaO L DNA repair exonuclease
MHFBIMFO_00782 0.0 L AAA domain
MHFBIMFO_00783 1.1e-178 yhaM L Shows a 3'-5' exoribonuclease activity
MHFBIMFO_00784 3e-27 yhaL S Sporulation protein YhaL
MHFBIMFO_00785 2.3e-151 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHFBIMFO_00788 3.7e-54 yhaI S Protein of unknown function (DUF1878)
MHFBIMFO_00789 6.7e-104 hpr K Negative regulator of protease production and sporulation
MHFBIMFO_00790 1.6e-18 yhaH S YtxH-like protein
MHFBIMFO_00791 6.5e-85 trpP S Tryptophan transporter TrpP
MHFBIMFO_00792 6.3e-75 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MHFBIMFO_00793 2.5e-138 ecsA V transporter (ATP-binding protein)
MHFBIMFO_00794 2e-222 ecsB U ABC transporter
MHFBIMFO_00795 1e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MHFBIMFO_00796 2.7e-239 yhfA C membrane
MHFBIMFO_00798 1.4e-95 traP 1.14.99.57 S enzyme involved in biosynthesis of extracellular polysaccharides
MHFBIMFO_00799 5.5e-200 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MHFBIMFO_00800 3.8e-184 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MHFBIMFO_00801 2.1e-271 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MHFBIMFO_00802 8.3e-102 yhgD K Transcriptional regulator
MHFBIMFO_00803 3.1e-236 yhgE S YhgE Pip N-terminal domain protein
MHFBIMFO_00804 3.1e-14 ydjF K DeoR C terminal sensor domain
MHFBIMFO_00805 7.9e-73 EGP Major facilitator Superfamily
MHFBIMFO_00806 8.1e-166 EG EamA-like transporter family
MHFBIMFO_00807 2.8e-64 aldA 1.2.1.21, 1.2.1.22 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHFBIMFO_00808 6.7e-104 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MHFBIMFO_00809 1.9e-65 ytkA S YtkA-like
MHFBIMFO_00810 8e-22 yhfH S YhfH-like protein
MHFBIMFO_00811 8.5e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
MHFBIMFO_00812 2.4e-297 fadD 6.2.1.3 IQ Activates fatty acids by binding to coenzyme A
MHFBIMFO_00813 6.9e-122 azlC E AzlC protein
MHFBIMFO_00814 5.7e-41 azlD S branched-chain amino acid
MHFBIMFO_00815 4.5e-209 yhfN 3.4.24.84 O Peptidase M48
MHFBIMFO_00816 1.7e-08 S IDEAL
MHFBIMFO_00817 1.7e-96 comK K Competence transcription factor
MHFBIMFO_00818 1.7e-145 S Mitochondrial biogenesis AIM24
MHFBIMFO_00819 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MHFBIMFO_00820 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MHFBIMFO_00821 4.2e-30 gerPF S Spore germination protein gerPA/gerPF
MHFBIMFO_00822 8.1e-73 gerPE S Spore germination protein GerPE
MHFBIMFO_00823 6.4e-24 gerPD S Spore germination protein
MHFBIMFO_00824 4.2e-99 gerPC S Spore germination protein
MHFBIMFO_00825 1.6e-32 gerPA S Spore germination protein
MHFBIMFO_00826 4.9e-226 P Protein of unknown function (DUF418)
MHFBIMFO_00827 2.3e-167 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MHFBIMFO_00828 3.9e-60 yisL S UPF0344 protein
MHFBIMFO_00829 2.1e-105 yisN S Protein of unknown function (DUF2777)
MHFBIMFO_00830 3.8e-159 yitS S protein conserved in bacteria
MHFBIMFO_00831 2.2e-25 S Protein of unknown function (DUF3813)
MHFBIMFO_00832 1.3e-156 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MHFBIMFO_00833 1.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MHFBIMFO_00834 6.2e-27 yjzC S YjzC-like protein
MHFBIMFO_00835 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHFBIMFO_00836 2.4e-149 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
MHFBIMFO_00838 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHFBIMFO_00839 5.6e-236 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHFBIMFO_00840 6.4e-153 yjaZ O Zn-dependent protease
MHFBIMFO_00841 1.5e-194 oppD P Belongs to the ABC transporter superfamily
MHFBIMFO_00842 1.3e-176 oppF P Belongs to the ABC transporter superfamily
MHFBIMFO_00843 6.2e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHFBIMFO_00844 6.9e-135 oppC EP binding-protein-dependent transport systems inner membrane component
MHFBIMFO_00845 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
MHFBIMFO_00846 2.3e-147 yjbA S Belongs to the UPF0736 family
MHFBIMFO_00847 2.7e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MHFBIMFO_00848 1.3e-49 S Domain of unknown function (DUF3899)
MHFBIMFO_00849 0.0 dppE_1 E ABC transporter substrate-binding protein
MHFBIMFO_00850 5.8e-153 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHFBIMFO_00851 6.3e-185 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHFBIMFO_00852 8e-199 oppD P Belongs to the ABC transporter superfamily
MHFBIMFO_00853 2e-177 oppF E Belongs to the ABC transporter superfamily
MHFBIMFO_00854 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHFBIMFO_00855 7.1e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHFBIMFO_00856 3.2e-236 yjbF S Competence protein
MHFBIMFO_00857 0.0 pepF E oligoendopeptidase F
MHFBIMFO_00859 9.1e-161 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MHFBIMFO_00860 1.4e-74 yjbI S COG2346 Truncated hemoglobins
MHFBIMFO_00861 4.3e-101 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHFBIMFO_00862 1.1e-106 yjbK S protein conserved in bacteria
MHFBIMFO_00863 6.9e-68 yjbL S Belongs to the UPF0738 family
MHFBIMFO_00864 1.2e-120 yjbM 2.7.6.5 S GTP pyrophosphokinase
MHFBIMFO_00865 4.9e-153 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHFBIMFO_00866 3.1e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHFBIMFO_00867 2e-137 prpE 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MHFBIMFO_00868 8.6e-142 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MHFBIMFO_00871 3.9e-83 cotY S Spore coat protein
MHFBIMFO_00872 3.8e-60 S Protein of unknown function (DUF1360)
MHFBIMFO_00874 1.1e-80 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHFBIMFO_00875 1.5e-83 spoVAC S stage V sporulation protein AC
MHFBIMFO_00876 4.5e-191 spoVAD I Stage V sporulation protein AD
MHFBIMFO_00877 1.1e-56 spoVAE S stage V sporulation protein
MHFBIMFO_00879 3.8e-38 spoVIF S Stage VI sporulation protein F
MHFBIMFO_00881 6.1e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHFBIMFO_00882 2e-94 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MHFBIMFO_00883 3.1e-141 yjcH P COG2382 Enterochelin esterase and related enzymes
MHFBIMFO_00889 3.2e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MHFBIMFO_00890 2e-55
MHFBIMFO_00891 5.1e-123 IQ Enoyl-(Acyl carrier protein) reductase
MHFBIMFO_00892 7.3e-169 yhaQ S ABC transporter, ATP-binding protein
MHFBIMFO_00893 7.1e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MHFBIMFO_00894 1.7e-262 pepC 3.4.22.40 E Papain family cysteine protease
MHFBIMFO_00895 3.6e-227 EGP Major facilitator Superfamily
MHFBIMFO_00896 1.9e-77 2.3.1.128 K Acetyltransferase (GNAT) domain
MHFBIMFO_00897 3.9e-09 sidE D nuclear chromosome segregation
MHFBIMFO_00898 5.7e-36 ykuS S Belongs to the UPF0180 family
MHFBIMFO_00899 2.1e-25
MHFBIMFO_00900 0.0 6.2.1.1, 6.2.1.16 I AMP-dependent synthetase
MHFBIMFO_00901 4.3e-92 ywrA P COG2059 Chromate transport protein ChrA
MHFBIMFO_00902 1.8e-102 chrA P COG2059 Chromate transport protein ChrA
MHFBIMFO_00903 1.5e-83 ywrC K Transcriptional regulator
MHFBIMFO_00904 1.3e-235 EGP Uncharacterised MFS-type transporter YbfB
MHFBIMFO_00905 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MHFBIMFO_00906 2.4e-236 3.5.1.4, 6.3.5.6, 6.3.5.7 J Belongs to the amidase family
MHFBIMFO_00907 1.3e-180 EGP Major facilitator Superfamily
MHFBIMFO_00909 6.1e-152 pocR K Sensory domain found in PocR
MHFBIMFO_00910 1.3e-232 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHFBIMFO_00911 1.8e-214 yxjG 2.1.1.14 E Methionine synthase
MHFBIMFO_00912 3.3e-49 esxA S Belongs to the WXG100 family
MHFBIMFO_00913 0.0 esaA S domain protein
MHFBIMFO_00914 1.3e-07 S WXG100 protein secretion system (Wss), protein EssA
MHFBIMFO_00915 9.5e-42 yukD S WXG100 protein secretion system (Wss), protein YukD
MHFBIMFO_00916 4.8e-225 essB S WXG100 protein secretion system (Wss), protein YukC
MHFBIMFO_00917 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MHFBIMFO_00918 4.2e-10 S Domain of unknown function (DUF5082)
MHFBIMFO_00919 4.1e-44
MHFBIMFO_00920 3.9e-228 S LXG domain of WXG superfamily
MHFBIMFO_00921 3.8e-140
MHFBIMFO_00922 1.9e-259 yjdA S LXG domain of WXG superfamily
MHFBIMFO_00923 9.6e-144
MHFBIMFO_00925 1.2e-290 L Transposase
MHFBIMFO_00926 5.6e-130
MHFBIMFO_00927 2.9e-81
MHFBIMFO_00928 6.8e-86 S Domain of unknown function (DUF5085)
MHFBIMFO_00930 4.8e-131 L PFAM Transposase, IS4-like
MHFBIMFO_00931 1.8e-33 L PFAM Transposase, IS4-like
MHFBIMFO_00932 2.5e-61 L PFAM Transposase, IS4-like
MHFBIMFO_00933 5.5e-142 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHFBIMFO_00934 1.3e-260 proP EGP Transporter
MHFBIMFO_00935 1.1e-15 S Ribbon-helix-helix protein, copG family
MHFBIMFO_00936 1.7e-212 L Transposase
MHFBIMFO_00937 9.9e-143 tesE Q COG3971 2-keto-4-pentenoate hydratase
MHFBIMFO_00938 7.8e-76 nsrR K Transcriptional regulator
MHFBIMFO_00939 1e-229 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHFBIMFO_00940 1.6e-124 S membrane transporter protein
MHFBIMFO_00941 4e-75 dps P Ferritin-like domain
MHFBIMFO_00942 1.4e-184 mocA S Oxidoreductase
MHFBIMFO_00943 1.1e-208 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MHFBIMFO_00944 4.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MHFBIMFO_00945 5.8e-85
MHFBIMFO_00946 9.5e-144 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MHFBIMFO_00947 2.8e-28 sspD S small acid-soluble spore protein
MHFBIMFO_00948 4.3e-19 S Stage 0 Sporulation Regulatory protein
MHFBIMFO_00950 1.8e-289 kinE 2.7.13.3 T Histidine kinase
MHFBIMFO_00951 5.2e-78 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHFBIMFO_00952 4.3e-71 XK27_09985 S Protein of unknown function (DUF1232)
MHFBIMFO_00954 0.0 clpE O Belongs to the ClpA ClpB family
MHFBIMFO_00955 4.3e-181 ykvI S membrane
MHFBIMFO_00956 7.3e-104 S Abortive infection protein
MHFBIMFO_00957 4.2e-26 ykvS S protein conserved in bacteria
MHFBIMFO_00958 1.8e-23
MHFBIMFO_00959 3.2e-40 ptsH G phosphocarrier protein HPr
MHFBIMFO_00960 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHFBIMFO_00961 2.8e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHFBIMFO_00962 5.9e-160 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MHFBIMFO_00963 9.8e-219 patA 2.6.1.1 E Aminotransferase
MHFBIMFO_00964 1.4e-164 cheV 2.7.13.3 T Chemotaxis protein CheV
MHFBIMFO_00965 1.1e-86 ykyB S YkyB-like protein
MHFBIMFO_00966 0.0 ydgH S drug exporters of the RND superfamily
MHFBIMFO_00967 0.0 T Diguanylate cyclase
MHFBIMFO_00968 2.6e-32
MHFBIMFO_00969 1.7e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHFBIMFO_00970 7.9e-171 3.5.1.4 C Acetamidase
MHFBIMFO_00971 5.8e-39 ykuJ S protein conserved in bacteria
MHFBIMFO_00972 6.5e-78 ykuL S CBS domain
MHFBIMFO_00973 4.1e-158 ccpC K Transcriptional regulator
MHFBIMFO_00974 1.2e-70 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHFBIMFO_00975 3.6e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHFBIMFO_00976 1.8e-18 S YhfH-like protein
MHFBIMFO_00977 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHFBIMFO_00978 6.8e-30 ykzG S Belongs to the UPF0356 family
MHFBIMFO_00979 1.6e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHFBIMFO_00980 4.5e-180 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHFBIMFO_00981 3.7e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHFBIMFO_00982 5.7e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHFBIMFO_00983 4.1e-34
MHFBIMFO_00985 2e-277 speA 4.1.1.19 E Arginine
MHFBIMFO_00986 4.5e-48 yktA S Belongs to the UPF0223 family
MHFBIMFO_00987 3.6e-119 yktB S Belongs to the UPF0637 family
MHFBIMFO_00988 1.4e-24
MHFBIMFO_00989 1.3e-150 suhB 3.1.3.25 G Inositol monophosphatase
MHFBIMFO_00990 6e-25 S Family of unknown function (DUF5325)
MHFBIMFO_00991 0.0 typA T GTP-binding protein TypA
MHFBIMFO_00992 5.4e-53 ylaH S YlaH-like protein
MHFBIMFO_00993 4.3e-250 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MHFBIMFO_00994 1.4e-89 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MHFBIMFO_00995 1.5e-43 ylaN S Belongs to the UPF0358 family
MHFBIMFO_00996 1.8e-218 ftsW D Belongs to the SEDS family
MHFBIMFO_00997 1e-176 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MHFBIMFO_00998 1.9e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHFBIMFO_00999 1.1e-198 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MHFBIMFO_01000 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHFBIMFO_01001 2.1e-114 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MHFBIMFO_01002 1.4e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MHFBIMFO_01003 2.6e-169 ctaG S cytochrome c oxidase
MHFBIMFO_01004 9.6e-64 ylbA S YugN-like family
MHFBIMFO_01005 6.4e-170 ylbC S protein with SCP PR1 domains
MHFBIMFO_01006 1e-84 yiiD Q protein, possibly involved in aromatic compounds catabolism
MHFBIMFO_01007 2e-70 ylbD S Putative coat protein
MHFBIMFO_01008 6.1e-38 ylbE S YlbE-like protein
MHFBIMFO_01009 1.1e-65
MHFBIMFO_01010 2.8e-73 ylbF S Belongs to the UPF0342 family
MHFBIMFO_01011 4.1e-45 ylbG S UPF0298 protein
MHFBIMFO_01012 7.7e-67 S Methylthioribose kinase
MHFBIMFO_01013 4.3e-109 rsmD 2.1.1.171 L Methyltransferase
MHFBIMFO_01014 1.7e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHFBIMFO_01015 1.7e-221 ylbJ S Sporulation integral membrane protein YlbJ
MHFBIMFO_01016 5.3e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
MHFBIMFO_01017 2.6e-194 ylbL T Belongs to the peptidase S16 family
MHFBIMFO_01018 7.7e-230 ylbM S Belongs to the UPF0348 family
MHFBIMFO_01019 1.2e-93 yceD S metal-binding, possibly nucleic acid-binding protein
MHFBIMFO_01020 1.1e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MHFBIMFO_01021 3.8e-82 rsfA S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MHFBIMFO_01022 8.1e-93 ylbP K n-acetyltransferase
MHFBIMFO_01023 4.5e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHFBIMFO_01024 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MHFBIMFO_01025 2e-79 mraZ K Belongs to the MraZ family
MHFBIMFO_01026 1.8e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHFBIMFO_01027 1.7e-39 ftsL D Essential cell division protein
MHFBIMFO_01028 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MHFBIMFO_01029 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MHFBIMFO_01030 4.8e-279 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHFBIMFO_01031 1.7e-78 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MHFBIMFO_01032 6.4e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHFBIMFO_01033 5.1e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHFBIMFO_01034 1.2e-189 spoVE D Belongs to the SEDS family
MHFBIMFO_01035 7.7e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHFBIMFO_01036 4e-120 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHFBIMFO_01037 1.6e-217 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHFBIMFO_01038 3.6e-189 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHFBIMFO_01039 7.3e-164 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MHFBIMFO_01040 3.5e-113 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHFBIMFO_01041 6.8e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHFBIMFO_01042 1.5e-43 ylmC S sporulation protein
MHFBIMFO_01043 5.3e-74 yocH CBM50 M 3D domain
MHFBIMFO_01044 3e-161 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MHFBIMFO_01045 2e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MHFBIMFO_01046 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHFBIMFO_01047 1.4e-38 yggT S membrane
MHFBIMFO_01048 9.8e-146 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MHFBIMFO_01049 3.3e-65 divIVA D Cell division initiation protein
MHFBIMFO_01050 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHFBIMFO_01052 1.3e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHFBIMFO_01053 4.6e-179 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHFBIMFO_01054 8.7e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHFBIMFO_01055 1.6e-168 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MHFBIMFO_01056 5.4e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHFBIMFO_01057 3.4e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MHFBIMFO_01058 0.0 carB 6.3.5.5 F Belongs to the CarB family
MHFBIMFO_01059 1.2e-140 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MHFBIMFO_01060 4e-181 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHFBIMFO_01061 4.4e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHFBIMFO_01062 4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHFBIMFO_01063 2.7e-171 S Nuclease-related domain
MHFBIMFO_01064 7.2e-211 L Transposase IS4 family protein
MHFBIMFO_01065 7.1e-39 3.2.2.21 K sequence-specific DNA binding
MHFBIMFO_01066 2.7e-193 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MHFBIMFO_01067 3.8e-75 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MHFBIMFO_01069 5e-35 S double-stranded DNA endodeoxyribonuclease activity
MHFBIMFO_01070 1.8e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHFBIMFO_01071 1.7e-246 EGP Major facilitator Superfamily
MHFBIMFO_01072 2.9e-67 EGP Major facilitator Superfamily
MHFBIMFO_01073 1.2e-36 lmrB EGP Major facilitator Superfamily
MHFBIMFO_01074 1.2e-195 S AI-2E family transporter
MHFBIMFO_01075 3.3e-50 S FAD binding domain
MHFBIMFO_01076 4e-167 yihP G MFS/sugar transport protein
MHFBIMFO_01077 2.9e-183 L Transposase DDE domain
MHFBIMFO_01078 6.6e-27
MHFBIMFO_01079 6.5e-90 O Methyltransferase
MHFBIMFO_01080 3.8e-68 2.1.1.163, 2.1.1.201 Q Methyltransferase type 11
MHFBIMFO_01081 1.1e-152 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHFBIMFO_01082 7.4e-91 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MHFBIMFO_01083 2.1e-142 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MHFBIMFO_01084 5.6e-167 yocS S -transporter
MHFBIMFO_01085 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MHFBIMFO_01086 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MHFBIMFO_01087 6e-152 yicC S stress-induced protein
MHFBIMFO_01088 3.8e-45 ylzA S Belongs to the UPF0296 family
MHFBIMFO_01089 3.7e-108 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MHFBIMFO_01090 3.4e-29 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHFBIMFO_01091 1.1e-220 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHFBIMFO_01092 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHFBIMFO_01093 1.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHFBIMFO_01094 1.7e-179 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHFBIMFO_01095 1.5e-255 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHFBIMFO_01096 1.2e-135 stp 3.1.3.16 T phosphatase
MHFBIMFO_01097 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MHFBIMFO_01098 1.2e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHFBIMFO_01099 4.1e-113 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MHFBIMFO_01100 2.8e-125 thiN 2.7.6.2 H thiamine pyrophosphokinase
MHFBIMFO_01101 5e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MHFBIMFO_01102 6.5e-60 asp S protein conserved in bacteria
MHFBIMFO_01103 5.7e-300 yloV S kinase related to dihydroxyacetone kinase
MHFBIMFO_01104 1.3e-119 sdaAB 4.3.1.17 E L-serine dehydratase
MHFBIMFO_01105 3.5e-155 sdaAA 4.3.1.17 E L-serine dehydratase
MHFBIMFO_01106 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHFBIMFO_01107 8.8e-99 fapR 5.3.1.23 Q Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MHFBIMFO_01108 2.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHFBIMFO_01109 4.2e-159 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MHFBIMFO_01110 2.1e-129 IQ reductase
MHFBIMFO_01111 1.3e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHFBIMFO_01112 2.4e-133 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHFBIMFO_01113 0.0 smc D Required for chromosome condensation and partitioning
MHFBIMFO_01114 4.6e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHFBIMFO_01115 2.6e-52 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHFBIMFO_01116 8.7e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHFBIMFO_01117 1.7e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MHFBIMFO_01118 5.5e-36 ylqC S Belongs to the UPF0109 family
MHFBIMFO_01119 1.1e-60 ylqD S YlqD protein
MHFBIMFO_01120 3.1e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHFBIMFO_01121 1.8e-141 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MHFBIMFO_01122 2.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHFBIMFO_01123 1.2e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MHFBIMFO_01124 1.2e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHFBIMFO_01125 1.8e-139 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHFBIMFO_01126 8.9e-234 CP_1081 D nuclear chromosome segregation
MHFBIMFO_01127 3.6e-45 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MHFBIMFO_01128 1.6e-213 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MHFBIMFO_01129 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MHFBIMFO_01130 6.9e-164 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MHFBIMFO_01131 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHFBIMFO_01132 1.5e-169 xerC L tyrosine recombinase XerC
MHFBIMFO_01133 4.3e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHFBIMFO_01134 2.1e-226 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHFBIMFO_01135 3e-134 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MHFBIMFO_01136 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MHFBIMFO_01137 4e-75 flgC N Belongs to the flagella basal body rod proteins family
MHFBIMFO_01138 1.1e-39 fliE N Flagellar hook-basal body complex protein FliE
MHFBIMFO_01139 1.3e-242 fliF N The M ring may be actively involved in energy transduction
MHFBIMFO_01140 2.7e-164 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHFBIMFO_01141 3e-131 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MHFBIMFO_01142 1.4e-248 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MHFBIMFO_01143 8.1e-73 fliJ N Flagellar biosynthesis chaperone
MHFBIMFO_01144 9.9e-48 ylxF S MgtE intracellular N domain
MHFBIMFO_01145 3.1e-300 fliK N Flagellar hook-length control
MHFBIMFO_01146 2.3e-108 flgD N Flagellar basal body rod modification protein
MHFBIMFO_01147 6.8e-41 flg N Putative flagellar
MHFBIMFO_01148 3.8e-118 flgG N Flagellar basal body rod
MHFBIMFO_01149 2.7e-65 fliL N Controls the rotational direction of flagella during chemotaxis
MHFBIMFO_01150 3.4e-183 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHFBIMFO_01151 1.3e-175 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MHFBIMFO_01152 5.5e-59 cheB 3.1.1.61, 3.5.1.44 T response regulator
MHFBIMFO_01153 8.4e-117 fliZ N Flagellar biosynthesis protein, FliO
MHFBIMFO_01154 2.6e-107 fliP N Plays a role in the flagellum-specific transport system
MHFBIMFO_01155 1.5e-37 fliQ N Role in flagellar biosynthesis
MHFBIMFO_01156 8.6e-134 fliR N Flagellar biosynthetic protein FliR
MHFBIMFO_01157 1.6e-186 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHFBIMFO_01158 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHFBIMFO_01159 1.1e-198 flhF N Flagellar biosynthesis regulator FlhF
MHFBIMFO_01160 1.8e-145 flhG D Belongs to the ParA family
MHFBIMFO_01161 4.9e-114 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MHFBIMFO_01162 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MHFBIMFO_01163 6.3e-70 cheW NT COG0835 Chemotaxis signal transduction protein
MHFBIMFO_01164 1.1e-113 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MHFBIMFO_01165 3.1e-84 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MHFBIMFO_01166 1.1e-136 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHFBIMFO_01167 3.5e-73 ylxL
MHFBIMFO_01168 1.1e-136 rpsB J Belongs to the universal ribosomal protein uS2 family
MHFBIMFO_01169 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHFBIMFO_01170 1.1e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MHFBIMFO_01171 6.9e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHFBIMFO_01172 7.4e-149 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHFBIMFO_01173 5.9e-146 cdsA 2.7.7.41 S Belongs to the CDS family
MHFBIMFO_01174 2.9e-194 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHFBIMFO_01175 1.5e-236 rasP M zinc metalloprotease
MHFBIMFO_01176 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHFBIMFO_01177 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHFBIMFO_01178 3e-248 L PFAM Transposase, IS4-like
MHFBIMFO_01179 7.1e-83 rimP S Required for maturation of 30S ribosomal subunits
MHFBIMFO_01180 2.8e-224 nusA K Participates in both transcription termination and antitermination
MHFBIMFO_01181 4.8e-45 ylxR K nucleic-acid-binding protein implicated in transcription termination
MHFBIMFO_01182 2.9e-48 ylxQ J ribosomal protein
MHFBIMFO_01183 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHFBIMFO_01184 8.6e-44 ylxP S protein conserved in bacteria
MHFBIMFO_01185 3.2e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHFBIMFO_01186 2.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHFBIMFO_01187 2.8e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MHFBIMFO_01188 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHFBIMFO_01189 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHFBIMFO_01190 3.6e-210 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MHFBIMFO_01191 1.5e-233 pepR S Belongs to the peptidase M16 family
MHFBIMFO_01192 8.1e-38 ymxH S YlmC YmxH family
MHFBIMFO_01193 1.5e-186 dpaA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MHFBIMFO_01194 2.6e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MHFBIMFO_01195 9.9e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHFBIMFO_01196 1.1e-228 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MHFBIMFO_01197 1.3e-159 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHFBIMFO_01198 0.0 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHFBIMFO_01199 5.8e-132 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MHFBIMFO_01200 4.3e-35 S YlzJ-like protein
MHFBIMFO_01201 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MHFBIMFO_01202 9.1e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MHFBIMFO_01203 8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MHFBIMFO_01204 2.6e-186 yufP S Belongs to the binding-protein-dependent transport system permease family
MHFBIMFO_01205 3.2e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
MHFBIMFO_01206 2.1e-238 ymfF S Peptidase M16
MHFBIMFO_01207 1.8e-245 ymfH S zinc protease
MHFBIMFO_01208 2.7e-138 1.1.1.100 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MHFBIMFO_01209 6.4e-41 ymfJ S Protein of unknown function (DUF3243)
MHFBIMFO_01210 1e-142 ymfK S Protein of unknown function (DUF3388)
MHFBIMFO_01211 3e-141 ymfM S protein conserved in bacteria
MHFBIMFO_01212 1.3e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHFBIMFO_01213 1e-226 cinA 3.5.1.42 S Belongs to the CinA family
MHFBIMFO_01214 6.4e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHFBIMFO_01215 5.6e-217 rny S Endoribonuclease that initiates mRNA decay
MHFBIMFO_01216 1.9e-152 ymdB S protein conserved in bacteria
MHFBIMFO_01217 3.3e-37 spoVS S Stage V sporulation protein S
MHFBIMFO_01218 1e-170 yegQ O Peptidase U32
MHFBIMFO_01219 2.6e-249 yegQ O COG0826 Collagenase and related proteases
MHFBIMFO_01220 1.3e-182 E Amino acid permease
MHFBIMFO_01221 8.2e-268 S PFAM Uncharacterised protein family UPF0236
MHFBIMFO_01222 2e-300 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MHFBIMFO_01223 2.3e-64 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MHFBIMFO_01224 6.2e-99 cotE S Outer spore coat protein E (CotE)
MHFBIMFO_01225 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHFBIMFO_01226 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHFBIMFO_01227 1.7e-25 2.1.1.80, 3.1.1.61 S protein secretion by the type IV secretion system
MHFBIMFO_01230 8.1e-188 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHFBIMFO_01231 1.2e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MHFBIMFO_01232 2.9e-176 spoVK O stage V sporulation protein K
MHFBIMFO_01233 3.3e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHFBIMFO_01234 7.2e-247 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MHFBIMFO_01235 2e-171 polA 2.7.7.7 L 5'3' exonuclease
MHFBIMFO_01236 3.6e-27 ypeQ S Zinc-finger
MHFBIMFO_01237 1.2e-31 cspD K Cold-shock protein
MHFBIMFO_01238 6e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MHFBIMFO_01239 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MHFBIMFO_01240 3.3e-86
MHFBIMFO_01241 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHFBIMFO_01242 1.5e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
MHFBIMFO_01243 2.3e-75 yphP S Belongs to the UPF0403 family
MHFBIMFO_01244 2.5e-106 ypjP S YpjP-like protein
MHFBIMFO_01245 5.7e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHFBIMFO_01246 1.2e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHFBIMFO_01247 2.2e-111 hlyIII S protein, Hemolysin III
MHFBIMFO_01248 3.5e-143 ypmR E COG2755 Lysophospholipase L1 and related esterases
MHFBIMFO_01249 5.1e-96 ypmS S protein conserved in bacteria
MHFBIMFO_01250 4.2e-277 rsmF 2.1.1.176, 2.1.1.178 J RNA-binding PUA-like domain of methyltransferase RsmF
MHFBIMFO_01251 1.6e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHFBIMFO_01252 7.3e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MHFBIMFO_01253 1.2e-09 S Protein of unknown function (Tiny_TM_bacill)
MHFBIMFO_01254 3.6e-191 NT CHASE3 domain
MHFBIMFO_01255 3.7e-14 yozE S Belongs to the UPF0346 family
MHFBIMFO_01256 6e-117 yodN
MHFBIMFO_01257 7.5e-25 yozD S YozD-like protein
MHFBIMFO_01258 4.1e-147 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MHFBIMFO_01259 1.7e-276 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MHFBIMFO_01260 8.7e-67 ypoP K transcriptional
MHFBIMFO_01261 1.2e-100 ykwD J protein with SCP PR1 domains
MHFBIMFO_01262 2.6e-250 norM V Multidrug efflux pump
MHFBIMFO_01264 6.6e-187 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHFBIMFO_01265 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MHFBIMFO_01266 1.6e-133 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MHFBIMFO_01267 1.5e-112 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MHFBIMFO_01269 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MHFBIMFO_01270 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MHFBIMFO_01271 3e-221 ymfD EGP Major facilitator Superfamily
MHFBIMFO_01272 1.3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHFBIMFO_01273 2.8e-244 arlS 2.7.13.3 T Histidine kinase
MHFBIMFO_01274 5.4e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
MHFBIMFO_01276 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MHFBIMFO_01277 1.4e-205 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MHFBIMFO_01278 2.6e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MHFBIMFO_01279 3.8e-83 rok S Repressor of ComK
MHFBIMFO_01280 8.6e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHFBIMFO_01282 3.2e-161 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MHFBIMFO_01283 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHFBIMFO_01284 3.5e-193 yceA S Belongs to the UPF0176 family
MHFBIMFO_01285 1.1e-129 yoqW S Belongs to the SOS response-associated peptidase family
MHFBIMFO_01286 2.9e-105 thiT S Proton-coupled thiamine transporter YuaJ
MHFBIMFO_01287 3.1e-169 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MHFBIMFO_01288 2.1e-79 S Domain in cystathionine beta-synthase and other proteins.
MHFBIMFO_01289 1.1e-158 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MHFBIMFO_01290 5.4e-129 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MHFBIMFO_01291 9.1e-107 yocH CBM50 M COG1388 FOG LysM repeat
MHFBIMFO_01292 0.0 topB2 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHFBIMFO_01293 3.3e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MHFBIMFO_01294 2.8e-179 corA P Mg2 transporter protein
MHFBIMFO_01295 1.1e-64 S CHY zinc finger
MHFBIMFO_01296 1.3e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHFBIMFO_01297 6.2e-111 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHFBIMFO_01298 5.1e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHFBIMFO_01299 2.6e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MHFBIMFO_01300 8.6e-113 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHFBIMFO_01301 1.4e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHFBIMFO_01302 5.1e-139 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHFBIMFO_01303 3.1e-116 hisE 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MHFBIMFO_01304 1e-40 yedF O Belongs to the sulfur carrier protein TusA family
MHFBIMFO_01305 2.3e-242 yedE S Sulphur transport
MHFBIMFO_01306 3.5e-161 rarD S -transporter
MHFBIMFO_01307 9.1e-221 ktrB P COG0168 Trk-type K transport systems, membrane components
MHFBIMFO_01308 2.3e-122 P COG0569 K transport systems, NAD-binding component
MHFBIMFO_01309 3e-136 ykrK S Domain of unknown function (DUF1836)
MHFBIMFO_01310 4.6e-15
MHFBIMFO_01311 6.3e-45 yxcD S Protein of unknown function (DUF2653)
MHFBIMFO_01312 9.2e-220 yeaN P COG2807 Cyanate permease
MHFBIMFO_01313 1.6e-310 ubiB S ABC1 family
MHFBIMFO_01314 4.7e-24 S ATP synthase, subunit b
MHFBIMFO_01315 7.7e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHFBIMFO_01317 2.7e-31 cspB K Cold shock
MHFBIMFO_01318 1.3e-119 folE 3.5.4.16 H GTP cyclohydrolase
MHFBIMFO_01319 2.2e-176 trxB_2 1.8.1.9 C FAD dependent oxidoreductase
MHFBIMFO_01320 1.6e-45 S Protein of unknown function (DUF1292)
MHFBIMFO_01321 5.2e-47 yxiS
MHFBIMFO_01322 0.0 bceB V ABC transporter (permease)
MHFBIMFO_01323 4e-136 bceA V ABC transporter, ATP-binding protein
MHFBIMFO_01324 5.6e-186 bceS 2.7.13.3 T Signal transduction histidine kinase
MHFBIMFO_01325 7.4e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHFBIMFO_01326 1.5e-61 yxaB GM pyruvyl transferase
MHFBIMFO_01327 2e-106 yxaB GM Polysaccharide pyruvyl transferase
MHFBIMFO_01328 9.9e-17
MHFBIMFO_01329 2.7e-231 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MHFBIMFO_01330 3.3e-200 yetN S Protein of unknown function (DUF3900)
MHFBIMFO_01331 1.4e-98
MHFBIMFO_01332 1.5e-255 tnpA1 L Transposase
MHFBIMFO_01333 2.7e-302 merA 1.16.1.1 C Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0)
MHFBIMFO_01334 1.7e-08
MHFBIMFO_01336 3.9e-235 ywoD EGP Major facilitator superfamily
MHFBIMFO_01337 2.5e-52 iscA S Heme biosynthesis protein HemY
MHFBIMFO_01338 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHFBIMFO_01339 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHFBIMFO_01340 3.2e-43 S Small, acid-soluble spore proteins, alpha/beta type
MHFBIMFO_01341 7.6e-62 S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MHFBIMFO_01342 4e-111 M effector of murein hydrolase
MHFBIMFO_01343 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHFBIMFO_01344 3.4e-109 M lytic transglycosylase activity
MHFBIMFO_01345 6.2e-09 S membrane
MHFBIMFO_01346 8.6e-19 sspP S Belongs to the SspP family
MHFBIMFO_01347 4.1e-40
MHFBIMFO_01348 6.5e-273 L RNA-directed DNA polymerase (reverse transcriptase)
MHFBIMFO_01349 7.1e-239 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MHFBIMFO_01350 4.4e-18 sspO S Belongs to the SspO family
MHFBIMFO_01351 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHFBIMFO_01353 1.7e-19 sspN S Small acid-soluble spore protein N family
MHFBIMFO_01354 4.1e-31 tlp S Belongs to the Tlp family
MHFBIMFO_01355 2.2e-75 yneP S thioesterase
MHFBIMFO_01356 8.4e-53 yneQ
MHFBIMFO_01357 1.4e-52 yneR S Belongs to the HesB IscA family
MHFBIMFO_01358 1e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHFBIMFO_01359 1.9e-71 yccU S CoA-binding protein
MHFBIMFO_01360 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHFBIMFO_01361 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHFBIMFO_01362 9.8e-146
MHFBIMFO_01363 3e-20 yjjL G Major facilitator superfamily
MHFBIMFO_01364 5.6e-161 yjjL G Major facilitator superfamily
MHFBIMFO_01365 2.6e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHFBIMFO_01366 0.0 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
MHFBIMFO_01367 5.6e-70 E Glyoxalase
MHFBIMFO_01370 8.6e-37 XK27_04860 K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHFBIMFO_01371 1.3e-201 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHFBIMFO_01372 3e-90 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MHFBIMFO_01375 1.2e-137 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MHFBIMFO_01376 5e-87 yvbK 3.1.3.25 K acetyltransferase
MHFBIMFO_01377 6e-96 VPA1573 J acetyltransferase
MHFBIMFO_01378 6.5e-75 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) family
MHFBIMFO_01379 7.1e-77 3.6.1.55 F Belongs to the Nudix hydrolase family
MHFBIMFO_01380 9.9e-247 cytX F Permease for cytosine/purines, uracil, thiamine, allantoin
MHFBIMFO_01381 9e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHFBIMFO_01382 1.6e-137 IQ Enoyl-(Acyl carrier protein) reductase
MHFBIMFO_01383 6.4e-124 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHFBIMFO_01384 7e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHFBIMFO_01385 1.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHFBIMFO_01386 2.5e-08 ykyB S YkyB-like protein
MHFBIMFO_01387 6.6e-127 yflK S protein conserved in bacteria
MHFBIMFO_01388 4.3e-42 S COG NOG14552 non supervised orthologous group
MHFBIMFO_01389 5.3e-43
MHFBIMFO_01390 6.5e-273 L RNA-directed DNA polymerase (reverse transcriptase)
MHFBIMFO_01392 7.5e-85 2.3.1.57 K Acetyltransferase (GNAT) domain
MHFBIMFO_01394 2.6e-61 S Psort location CytoplasmicMembrane, score
MHFBIMFO_01395 2.5e-152 S Psort location CytoplasmicMembrane, score
MHFBIMFO_01396 6.9e-121 yfiR K Transcriptional regulator
MHFBIMFO_01397 5.6e-228 yfiS EGP Major facilitator Superfamily
MHFBIMFO_01398 9.6e-138 thiX 2.7.1.50 P binding-protein-dependent transport systems inner membrane component
MHFBIMFO_01399 4e-176 nrtA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHFBIMFO_01401 7.9e-75 S Glyoxalase bleomycin resistance protein dioxygenase
MHFBIMFO_01402 6.3e-139 yitD 4.4.1.19 S synthase
MHFBIMFO_01403 7.2e-132 comB 3.1.3.71 H Belongs to the ComB family
MHFBIMFO_01404 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MHFBIMFO_01405 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MHFBIMFO_01406 1.3e-108
MHFBIMFO_01407 9.7e-135 mta K transcriptional
MHFBIMFO_01408 5.4e-272 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
MHFBIMFO_01409 2.2e-179 yjlA EG Putative multidrug resistance efflux transporter
MHFBIMFO_01410 8.2e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHFBIMFO_01411 2.9e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHFBIMFO_01412 6.9e-215 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHFBIMFO_01413 3.3e-261 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHFBIMFO_01414 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MHFBIMFO_01415 5.7e-181 kefA M Mechanosensitive ion channel
MHFBIMFO_01416 2.3e-192 S COG0491 Zn-dependent hydrolases, including glyoxylases
MHFBIMFO_01417 9.1e-56 I SCP-2 sterol transfer family
MHFBIMFO_01419 4e-104 S Appr-1'-p processing enzyme
MHFBIMFO_01420 4.4e-25 sspH S small acid-soluble spore protein
MHFBIMFO_01421 9.2e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFBIMFO_01422 1.1e-209 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
MHFBIMFO_01423 6.7e-292 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHFBIMFO_01424 1.9e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MHFBIMFO_01425 6.1e-143 S Sucrose-6F-phosphate phosphohydrolase
MHFBIMFO_01426 8.4e-105 yozB S membrane
MHFBIMFO_01427 9e-60
MHFBIMFO_01428 2.3e-76 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHFBIMFO_01429 2.2e-182 ldh1 1.1.1.27 C Belongs to the LDH MDH superfamily
MHFBIMFO_01431 3.3e-209 yxaM U MFS_1 like family
MHFBIMFO_01432 3e-08 S Protein of unknown function (DUF2785)
MHFBIMFO_01433 2.7e-132 IQ Enoyl-(Acyl carrier protein) reductase
MHFBIMFO_01434 8e-216 fsr P COG0477 Permeases of the major facilitator superfamily
MHFBIMFO_01435 1.4e-77 sleB 3.5.1.28 M Cell wall
MHFBIMFO_01436 2.7e-148 xth 3.1.11.2 L exodeoxyribonuclease III
MHFBIMFO_01437 1.8e-156 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MHFBIMFO_01438 3e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MHFBIMFO_01439 2.3e-193 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MHFBIMFO_01440 1.1e-212 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHFBIMFO_01441 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHFBIMFO_01442 6.3e-198 G Glycosyl hydrolases family 15
MHFBIMFO_01443 7.3e-21 S YpzG-like protein
MHFBIMFO_01444 6.5e-82 Q protein disulfide oxidoreductase activity
MHFBIMFO_01445 2.1e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MHFBIMFO_01446 3.7e-119 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHFBIMFO_01447 7.6e-228 mntH P H( )-stimulated, divalent metal cation uptake system
MHFBIMFO_01448 1.6e-76 dps P Ferritin-like domain
MHFBIMFO_01449 1.7e-81 V VanZ like family
MHFBIMFO_01450 1.6e-171 yhcI S ABC-2 family transporter protein
MHFBIMFO_01451 2.8e-171 ydbJ V ABC transporter, ATP-binding protein
MHFBIMFO_01452 6.3e-57
MHFBIMFO_01453 1.8e-167 murB 1.3.1.98 M cell wall formation
MHFBIMFO_01454 2.3e-79 S Protein of unknown function (DUF1189)
MHFBIMFO_01455 1.4e-37 S Protein of unknown function (DUF1450)
MHFBIMFO_01456 3.6e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHFBIMFO_01457 1.1e-71 I MaoC like domain
MHFBIMFO_01458 1.9e-80 I N-terminal half of MaoC dehydratase
MHFBIMFO_01459 4.1e-130 IQ Enoyl-(Acyl carrier protein) reductase
MHFBIMFO_01461 2.4e-200 selU S tRNA 2-selenouridine synthase
MHFBIMFO_01462 8.1e-196 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
MHFBIMFO_01463 6.5e-136 T Calcineurin-like phosphoesterase superfamily domain
MHFBIMFO_01464 2.9e-193 yraQ S Predicted permease
MHFBIMFO_01465 1.9e-231 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHFBIMFO_01466 6.5e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHFBIMFO_01467 6.4e-73 yjlC S Protein of unknown function (DUF1641)
MHFBIMFO_01468 7.4e-222 yjlD 1.6.99.3 C NADH dehydrogenase
MHFBIMFO_01469 5.7e-230 nrnB S phosphohydrolase (DHH superfamily)
MHFBIMFO_01470 2.4e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHFBIMFO_01471 2.3e-130 yvpB NU protein conserved in bacteria
MHFBIMFO_01472 3.8e-50 tnrA K transcriptional
MHFBIMFO_01473 4.2e-109 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHFBIMFO_01474 1.9e-23 S Virus attachment protein p12 family
MHFBIMFO_01475 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MHFBIMFO_01476 4.9e-37 feoA P COG1918 Fe2 transport system protein A
MHFBIMFO_01477 2.2e-221 dapL 2.6.1.83 E Aminotransferase
MHFBIMFO_01478 3.8e-265 argH 4.3.2.1 E argininosuccinate lyase
MHFBIMFO_01479 6.2e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHFBIMFO_01480 8.2e-179 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHFBIMFO_01481 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MHFBIMFO_01482 1.5e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MHFBIMFO_01483 3.9e-226 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MHFBIMFO_01484 5.1e-142 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MHFBIMFO_01485 3.1e-234 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHFBIMFO_01486 2e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHFBIMFO_01488 1e-81
MHFBIMFO_01489 1e-37 P catalase activity
MHFBIMFO_01490 1.7e-81
MHFBIMFO_01491 2.3e-30 cspD K Cold shock
MHFBIMFO_01493 9e-175 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MHFBIMFO_01494 1.1e-283 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MHFBIMFO_01495 1.1e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHFBIMFO_01496 5.6e-77 yneK S Protein of unknown function (DUF2621)
MHFBIMFO_01497 4.6e-77 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MHFBIMFO_01498 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MHFBIMFO_01499 1.6e-129 ccdA O cytochrome c biogenesis protein
MHFBIMFO_01500 6.8e-28 yneF S UPF0154 protein
MHFBIMFO_01501 5.3e-72 yneE S Sporulation inhibitor of replication protein sirA
MHFBIMFO_01502 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHFBIMFO_01503 3.4e-33 ynzC S UPF0291 protein
MHFBIMFO_01504 5.2e-116 yneB L resolvase
MHFBIMFO_01505 3.6e-52 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MHFBIMFO_01506 1.2e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHFBIMFO_01507 4.4e-263 glnA 6.3.1.2 E glutamine synthetase
MHFBIMFO_01508 6.1e-64 glnR K transcriptional
MHFBIMFO_01509 0.0 S Dynamin family
MHFBIMFO_01510 1.3e-33
MHFBIMFO_01511 4.9e-143 f42a O prohibitin homologues
MHFBIMFO_01512 1.2e-233 pbuX F xanthine
MHFBIMFO_01513 4.2e-101 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHFBIMFO_01514 6.1e-301 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MHFBIMFO_01515 4.5e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MHFBIMFO_01516 9e-47 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHFBIMFO_01517 4e-101 ypsA S Belongs to the UPF0398 family
MHFBIMFO_01518 5.4e-45 cotD S Inner spore coat protein D
MHFBIMFO_01520 2.7e-257 yprB L RNase_H superfamily
MHFBIMFO_01521 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MHFBIMFO_01522 2.5e-77 hspX O Belongs to the small heat shock protein (HSP20) family
MHFBIMFO_01524 1.8e-60 yppG S YppG-like protein
MHFBIMFO_01525 1.1e-62 yppE S Bacterial domain of unknown function (DUF1798)
MHFBIMFO_01528 5e-113 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHFBIMFO_01529 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHFBIMFO_01530 2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHFBIMFO_01531 3e-130 dnaD L DNA replication protein DnaD
MHFBIMFO_01532 9.2e-261 asnS 6.1.1.22 J asparaginyl-tRNA
MHFBIMFO_01533 2e-219 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MHFBIMFO_01534 1.3e-78 ypmB S protein conserved in bacteria
MHFBIMFO_01535 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MHFBIMFO_01536 2.5e-62 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MHFBIMFO_01537 2e-160 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MHFBIMFO_01538 6.4e-151 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MHFBIMFO_01539 1.8e-168 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHFBIMFO_01540 7.6e-230 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHFBIMFO_01541 5.2e-215 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MHFBIMFO_01542 5.6e-132 bshB1 S proteins, LmbE homologs
MHFBIMFO_01543 1.5e-149 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHFBIMFO_01544 9.9e-58 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MHFBIMFO_01545 2.4e-161 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MHFBIMFO_01546 3.1e-81 queT S QueT transporter
MHFBIMFO_01547 2.4e-103 yugP S Zn-dependent protease
MHFBIMFO_01548 3.5e-143 ypjB S sporulation protein
MHFBIMFO_01549 1.3e-110 ypjA S membrane
MHFBIMFO_01550 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MHFBIMFO_01551 1.2e-126 petB C COG1290 Cytochrome b subunit of the bc complex
MHFBIMFO_01552 1e-98 qcrA C Menaquinol-cytochrome c reductase
MHFBIMFO_01553 1.1e-80 ypiF S Protein of unknown function (DUF2487)
MHFBIMFO_01554 3.5e-97 ypiB S Belongs to the UPF0302 family
MHFBIMFO_01555 5e-240 S COG0457 FOG TPR repeat
MHFBIMFO_01556 3e-240 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHFBIMFO_01557 2.6e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MHFBIMFO_01558 7.9e-210 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHFBIMFO_01559 1.3e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MHFBIMFO_01560 2.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHFBIMFO_01561 1.1e-220 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHFBIMFO_01562 1.7e-145 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MHFBIMFO_01563 1.1e-74 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MHFBIMFO_01564 1.3e-176 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHFBIMFO_01565 6.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MHFBIMFO_01566 3.5e-146 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MHFBIMFO_01567 8.7e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MHFBIMFO_01568 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHFBIMFO_01569 8.3e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHFBIMFO_01570 7.6e-137 yphF
MHFBIMFO_01571 1.4e-08 yphE S Protein of unknown function (DUF2768)
MHFBIMFO_01572 1.6e-191 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MHFBIMFO_01573 5.5e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MHFBIMFO_01574 4.9e-20 yphA
MHFBIMFO_01575 7.3e-14 S YpzI-like protein
MHFBIMFO_01576 9.4e-206 rpsA 1.17.7.4 J Ribosomal protein S1
MHFBIMFO_01577 3.7e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MHFBIMFO_01578 9.3e-118 ypfA M Flagellar protein YcgR
MHFBIMFO_01579 1.5e-258 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MHFBIMFO_01580 5.7e-149 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MHFBIMFO_01581 1.5e-126 prsW S Involved in the degradation of specific anti-sigma factors
MHFBIMFO_01582 1.5e-180 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MHFBIMFO_01583 2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHFBIMFO_01584 5.4e-107 mecB NOT Negative regulator of genetic competence (MecA)
MHFBIMFO_01585 3.4e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
MHFBIMFO_01586 2.6e-30 cotJA S Spore coat associated protein JA (CotJA)
MHFBIMFO_01587 1.2e-44 cotJB S CotJB protein
MHFBIMFO_01588 2e-103 cotJC P Spore Coat
MHFBIMFO_01589 1.2e-79 ypbF S Protein of unknown function (DUF2663)
MHFBIMFO_01591 1.1e-101 ypbD S metal-dependent membrane protease
MHFBIMFO_01592 4.1e-278 recQ 3.6.4.12 L DNA helicase
MHFBIMFO_01593 3.6e-207 ypbB 5.1.3.1 S protein conserved in bacteria
MHFBIMFO_01594 7.8e-41 fer C Ferredoxin
MHFBIMFO_01595 2.4e-96 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHFBIMFO_01596 1.7e-136 M COG0739 Membrane proteins related to metalloendopeptidases
MHFBIMFO_01597 0.0 resE 2.7.13.3 T Histidine kinase
MHFBIMFO_01598 3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHFBIMFO_01599 2.2e-229 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MHFBIMFO_01600 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MHFBIMFO_01601 9.6e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MHFBIMFO_01602 1.3e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MHFBIMFO_01603 1.1e-87 spmB S Spore maturation protein
MHFBIMFO_01604 5.2e-96 spmA S Spore maturation protein
MHFBIMFO_01605 1.4e-201 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MHFBIMFO_01606 1.2e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHFBIMFO_01607 1.7e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHFBIMFO_01609 2.2e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHFBIMFO_01610 1.6e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHFBIMFO_01611 4.9e-271 spoVAF EG Stage V sporulation protein AF
MHFBIMFO_01612 1.6e-105 spoVAEA S Stage V sporulation protein AE
MHFBIMFO_01613 1.9e-66 spoVAB S Stage V sporulation protein AB
MHFBIMFO_01614 6.5e-108 spoVAA S Stage V sporulation protein AA
MHFBIMFO_01615 1.4e-133 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHFBIMFO_01616 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MHFBIMFO_01617 2.5e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MHFBIMFO_01618 5.6e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MHFBIMFO_01620 3.6e-168 xerD L recombinase XerD
MHFBIMFO_01621 1.7e-34 S Protein of unknown function (DUF4227)
MHFBIMFO_01622 1.6e-85 fur P Belongs to the Fur family
MHFBIMFO_01623 8.2e-106 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MHFBIMFO_01624 3.9e-231 yqxK 3.6.4.12 L DNA helicase
MHFBIMFO_01625 3.1e-98 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MHFBIMFO_01627 1.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MHFBIMFO_01628 1.6e-09 S Protein of unknown function (DUF3886)
MHFBIMFO_01629 5.6e-110 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MHFBIMFO_01630 1.3e-213 yaaN P Belongs to the TelA family
MHFBIMFO_01631 1.7e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MHFBIMFO_01632 2.2e-241 yaaH_2 M Glycoside Hydrolase Family
MHFBIMFO_01633 2.7e-55 S YolD-like protein
MHFBIMFO_01634 1.3e-240 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHFBIMFO_01635 5.3e-147 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHFBIMFO_01636 2.6e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHFBIMFO_01637 5.9e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHFBIMFO_01638 6.4e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHFBIMFO_01639 1e-226 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHFBIMFO_01640 1.2e-77 cheW NT COG0835 Chemotaxis signal transduction protein
MHFBIMFO_01641 3.9e-204 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MHFBIMFO_01642 3.6e-93 yqjB S protein conserved in bacteria
MHFBIMFO_01643 9.3e-77 yqiW S Belongs to the UPF0403 family
MHFBIMFO_01644 3.4e-166 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MHFBIMFO_01645 2.9e-219 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHFBIMFO_01646 3.9e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHFBIMFO_01647 5.9e-188 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHFBIMFO_01648 1e-262 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHFBIMFO_01649 3e-209 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHFBIMFO_01650 4.4e-18 T transcription factor binding
MHFBIMFO_01651 1.4e-56 1.1.1.169, 1.3.1.12, 4.2.1.51, 5.4.99.5 E prephenate dehydrogenase (NADP+) activity
MHFBIMFO_01652 4.4e-36 yqzF S Protein of unknown function (DUF2627)
MHFBIMFO_01653 7.7e-132 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MHFBIMFO_01654 4.4e-138 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MHFBIMFO_01655 3.9e-232 rseP 3.4.21.116 M Stage IV sporulation protein B
MHFBIMFO_01656 5e-296 recN L May be involved in recombinational repair of damaged DNA
MHFBIMFO_01657 5.4e-80 argR K Regulates arginine biosynthesis genes
MHFBIMFO_01658 2.9e-148 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MHFBIMFO_01659 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHFBIMFO_01660 6.8e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHFBIMFO_01661 3.1e-31 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHFBIMFO_01662 3.5e-228 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHFBIMFO_01663 1.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHFBIMFO_01664 1.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHFBIMFO_01665 1.1e-68 yqhY S protein conserved in bacteria
MHFBIMFO_01666 3.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MHFBIMFO_01667 1.8e-81 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHFBIMFO_01668 1.1e-23 spoIIIAH S SpoIIIAH-like protein
MHFBIMFO_01669 5.5e-79 spoIIIAH S SpoIIIAH-like protein
MHFBIMFO_01670 6.6e-111 spoIIIAG S stage III sporulation protein AG
MHFBIMFO_01671 1.8e-105 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MHFBIMFO_01672 9e-175 spoIIIAE S stage III sporulation protein AE
MHFBIMFO_01673 1e-58 spoIIIAD S Stage III sporulation protein AD
MHFBIMFO_01674 1.4e-27 spoIIIAC S stage III sporulation protein AC
MHFBIMFO_01675 4.4e-86 spoIIIAB S Stage III sporulation protein
MHFBIMFO_01676 1.2e-171 spoIIIAA S stage III sporulation protein AA
MHFBIMFO_01677 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHFBIMFO_01678 1.7e-156 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MHFBIMFO_01679 9.6e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MHFBIMFO_01680 2.4e-86 yqhR S Conserved membrane protein YqhR
MHFBIMFO_01681 2.7e-166 yqhQ S Protein of unknown function (DUF1385)
MHFBIMFO_01682 8.2e-10 yqhP
MHFBIMFO_01683 8.7e-167 yqhO S esterase of the alpha-beta hydrolase superfamily
MHFBIMFO_01684 7.8e-72 bktB 2.3.1.9 I Belongs to the thiolase family
MHFBIMFO_01685 0.0 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
MHFBIMFO_01686 1.4e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MHFBIMFO_01687 4.5e-67 yqhL P COG0607 Rhodanese-related sulfurtransferase
MHFBIMFO_01688 3.7e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHFBIMFO_01689 5.3e-256 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHFBIMFO_01690 5.8e-216 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MHFBIMFO_01691 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHFBIMFO_01692 1.2e-154 yqhG S Bacterial protein YqhG of unknown function
MHFBIMFO_01693 1.1e-09 yqzE S YqzE-like protein
MHFBIMFO_01694 2.6e-100 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MHFBIMFO_01695 8.7e-60 S ComG operon protein 7
MHFBIMFO_01696 3.3e-83 comGF U COG4940 Competence protein ComGF
MHFBIMFO_01698 7.9e-76 gspH NU COG2165 Type II secretory pathway, pseudopilin PulG
MHFBIMFO_01699 5.3e-50 comGC U Required for transformation and DNA binding
MHFBIMFO_01700 3.9e-176 comGB NU COG1459 Type II secretory pathway, component PulF
MHFBIMFO_01701 7.4e-211 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MHFBIMFO_01702 4e-130 K Helix-turn-helix domain
MHFBIMFO_01703 5.7e-36 yqgY S Protein of unknown function (DUF2626)
MHFBIMFO_01704 5e-124 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MHFBIMFO_01705 2.9e-21 yqgW S Protein of unknown function (DUF2759)
MHFBIMFO_01706 3.5e-169 glcK 2.7.1.2 G Glucokinase
MHFBIMFO_01707 3.3e-30 yqgQ S protein conserved in bacteria
MHFBIMFO_01708 3.7e-202 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MHFBIMFO_01710 1.6e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MHFBIMFO_01711 2e-56 yqzD
MHFBIMFO_01712 0.0 mrdA 3.4.16.4 M penicillin-binding protein
MHFBIMFO_01713 9.4e-220 yqgE EGP Major facilitator superfamily
MHFBIMFO_01714 3.7e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MHFBIMFO_01715 5.2e-56 fimV NU Tfp pilus assembly protein FimV
MHFBIMFO_01716 1.2e-200 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MHFBIMFO_01717 4.4e-114 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MHFBIMFO_01718 2.2e-75 zur P Belongs to the Fur family
MHFBIMFO_01719 1.6e-141 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHFBIMFO_01720 1.3e-142 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHFBIMFO_01721 1e-19 yqfT S Protein of unknown function (DUF2624)
MHFBIMFO_01722 2e-133 cwlO CBM50 M protein conserved in bacteria
MHFBIMFO_01723 3.9e-170 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHFBIMFO_01724 7.2e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHFBIMFO_01726 1.5e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MHFBIMFO_01727 6.6e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHFBIMFO_01728 6.6e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
MHFBIMFO_01729 1.5e-64 cccA C Cytochrome C oxidase, cbb3-type, subunit III
MHFBIMFO_01730 5.8e-89
MHFBIMFO_01731 5.7e-203 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHFBIMFO_01732 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHFBIMFO_01733 1.6e-146 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHFBIMFO_01734 3.4e-112 ccpN K CBS domain
MHFBIMFO_01735 1.6e-145 recO L Involved in DNA repair and RecF pathway recombination
MHFBIMFO_01736 6.7e-08 S YqzL-like protein
MHFBIMFO_01737 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHFBIMFO_01738 7.9e-67 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MHFBIMFO_01739 4.2e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHFBIMFO_01740 0.0 yqfF S membrane-associated HD superfamily hydrolase
MHFBIMFO_01741 6.1e-174 phoH T Phosphate starvation-inducible protein PhoH
MHFBIMFO_01742 1.2e-224 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MHFBIMFO_01743 3.2e-46 yqfC S sporulation protein YqfC
MHFBIMFO_01744 6.6e-70 yqeY S Yqey-like protein
MHFBIMFO_01745 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MHFBIMFO_01746 2.6e-48 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MHFBIMFO_01747 1.5e-156 yqeW P COG1283 Na phosphate symporter
MHFBIMFO_01748 4.2e-261 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MHFBIMFO_01749 2.7e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHFBIMFO_01750 5.1e-173 prmA J Methylates ribosomal protein L11
MHFBIMFO_01751 3.8e-207 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHFBIMFO_01752 5.6e-309 dnaK O Heat shock 70 kDa protein
MHFBIMFO_01753 3.8e-90 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHFBIMFO_01754 8.3e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHFBIMFO_01755 3e-220 hemN H Involved in the biosynthesis of porphyrin-containing compound
MHFBIMFO_01756 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHFBIMFO_01757 1.1e-220 spoIIP M stage II sporulation protein P
MHFBIMFO_01758 1.2e-202 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MHFBIMFO_01759 5.2e-35 rpsT J Binds directly to 16S ribosomal RNA
MHFBIMFO_01760 1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
MHFBIMFO_01761 1.1e-07 S YqzM-like protein
MHFBIMFO_01762 0.0 comEC S Competence protein ComEC
MHFBIMFO_01763 2.1e-111 comEB 3.5.4.12 F COG2131 Deoxycytidylate deaminase
MHFBIMFO_01764 1.2e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MHFBIMFO_01765 1.3e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHFBIMFO_01766 2.5e-146 cmoA S Methyltransferase domain
MHFBIMFO_01767 3.7e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHFBIMFO_01768 3.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MHFBIMFO_01769 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHFBIMFO_01770 3.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MHFBIMFO_01771 9.5e-163 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHFBIMFO_01772 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MHFBIMFO_01773 2.6e-94 yqeG S hydrolase of the HAD superfamily
MHFBIMFO_01774 6e-260 glcF C Glycolate oxidase
MHFBIMFO_01775 5.5e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
MHFBIMFO_01776 6.4e-207 ysfB KT regulator
MHFBIMFO_01777 1.1e-280 mco 1.16.3.3 Q multicopper oxidases
MHFBIMFO_01778 1.8e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
MHFBIMFO_01779 7.8e-67 perX S DsrE/DsrF-like family
MHFBIMFO_01780 2.4e-39 O Glutaredoxin
MHFBIMFO_01781 8.2e-55 P Rhodanese Homology Domain
MHFBIMFO_01782 0.0 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHFBIMFO_01783 3.6e-290 L Transposase
MHFBIMFO_01784 3e-153 S PFAM Uncharacterised protein family UPF0236
MHFBIMFO_01785 3.9e-75 hsp18 O Belongs to the small heat shock protein (HSP20) family
MHFBIMFO_01786 5.4e-23 S Short C-terminal domain
MHFBIMFO_01787 6.6e-105 CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MHFBIMFO_01788 1.2e-116 S TPM domain
MHFBIMFO_01789 6.5e-78 lemA S LemA family
MHFBIMFO_01790 4.3e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHFBIMFO_01791 1.2e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHFBIMFO_01792 9.1e-119 S VIT family
MHFBIMFO_01793 1.6e-155 czcD P COG1230 Co Zn Cd efflux system component
MHFBIMFO_01794 4.2e-15 sda S Sporulation inhibitor A
MHFBIMFO_01795 2.8e-65 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHFBIMFO_01796 2.1e-126 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHFBIMFO_01797 4.8e-293 ahpF O Alkyl hydroperoxide reductase
MHFBIMFO_01798 3.8e-107 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MHFBIMFO_01800 1.7e-10 S YrhC-like protein
MHFBIMFO_01801 1.1e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHFBIMFO_01802 3.4e-29 yrzA S Protein of unknown function (DUF2536)
MHFBIMFO_01803 7.4e-56 yrrS S Protein of unknown function (DUF1510)
MHFBIMFO_01804 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHFBIMFO_01805 6.8e-113 udk 2.7.1.48 F Cytidine monophosphokinase
MHFBIMFO_01806 4.6e-117 yrrM 2.1.1.104 S O-methyltransferase
MHFBIMFO_01807 1.4e-206 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHFBIMFO_01808 1.5e-41 yrzB S Belongs to the UPF0473 family
MHFBIMFO_01809 6.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHFBIMFO_01810 5.8e-45 yrzL S Belongs to the UPF0297 family
MHFBIMFO_01811 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHFBIMFO_01812 8.8e-177 yrrI S AI-2E family transporter
MHFBIMFO_01814 1.8e-29 yrzR
MHFBIMFO_01815 1.6e-73 yndM S Protein of unknown function (DUF2512)
MHFBIMFO_01816 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHFBIMFO_01817 1.3e-125 S COG0457 FOG TPR repeat
MHFBIMFO_01818 9.8e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHFBIMFO_01819 3.1e-209 iscS 2.8.1.7 E Cysteine desulfurase
MHFBIMFO_01820 2.3e-72 cymR K Transcriptional regulator
MHFBIMFO_01821 8.8e-136 IQ Short-chain dehydrogenase reductase sdr
MHFBIMFO_01822 9.5e-239 cshA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MHFBIMFO_01823 4.1e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MHFBIMFO_01824 2.2e-163 ybaS 1.1.1.58 S Na -dependent transporter
MHFBIMFO_01826 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MHFBIMFO_01827 1.2e-249 hisS 6.1.1.21 J histidyl-tRNA synthetase
MHFBIMFO_01829 1e-276 lytH 3.5.1.28, 6.1.1.12 M COG3103 SH3 domain protein
MHFBIMFO_01830 1.8e-307 yhcA5 EGP Major facilitator Superfamily
MHFBIMFO_01831 1.4e-108 emrA V COG1566 Multidrug resistance efflux pump
MHFBIMFO_01832 3.1e-72 K helix_turn_helix multiple antibiotic resistance protein
MHFBIMFO_01833 2.5e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHFBIMFO_01834 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHFBIMFO_01835 5.3e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHFBIMFO_01836 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MHFBIMFO_01837 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MHFBIMFO_01838 3.6e-60 yrzD S Post-transcriptional regulator
MHFBIMFO_01839 3.9e-271 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHFBIMFO_01840 1.4e-105 yrbG S membrane
MHFBIMFO_01841 1.9e-60 yrzE S Protein of unknown function (DUF3792)
MHFBIMFO_01842 7.4e-42 yajC U Preprotein translocase subunit YajC
MHFBIMFO_01843 6.9e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHFBIMFO_01844 2.2e-193 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHFBIMFO_01845 5.4e-27 yrzS S Protein of unknown function (DUF2905)
MHFBIMFO_01846 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHFBIMFO_01847 3.4e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHFBIMFO_01848 4.5e-129 yebC K transcriptional regulatory protein
MHFBIMFO_01849 3.3e-191 1.1.1.34, 2.7.1.89 M choline kinase involved in LPS biosynthesis
MHFBIMFO_01850 3.8e-144 safA M spore coat assembly protein SafA
MHFBIMFO_01851 3.5e-97 niaR S small molecule binding protein (contains 3H domain)
MHFBIMFO_01852 1.9e-158 pheA 4.2.1.51 E Prephenate dehydratase
MHFBIMFO_01853 9e-75 pheB 5.4.99.5 S Belongs to the UPF0735 family
MHFBIMFO_01854 4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHFBIMFO_01855 2.3e-98 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MHFBIMFO_01856 1.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MHFBIMFO_01857 4.6e-52 ysxB J ribosomal protein
MHFBIMFO_01858 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
MHFBIMFO_01859 3.4e-280 rng J ribonuclease, Rne Rng family
MHFBIMFO_01860 7.5e-163 spoIVFB S Stage IV sporulation protein
MHFBIMFO_01861 3e-136 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MHFBIMFO_01862 1e-145 minD D Belongs to the ParA family
MHFBIMFO_01863 1e-122 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHFBIMFO_01864 4e-87 mreD M shape-determining protein
MHFBIMFO_01865 6.2e-141 mreC M Involved in formation and maintenance of cell shape
MHFBIMFO_01866 1.6e-185 mreB D Rod shape-determining protein MreB
MHFBIMFO_01867 1.3e-122 radC E Belongs to the UPF0758 family
MHFBIMFO_01868 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
MHFBIMFO_01869 1.3e-166 spoIIB
MHFBIMFO_01870 3.8e-142 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MHFBIMFO_01871 5.4e-103
MHFBIMFO_01872 2e-91 pilN NU PFAM Fimbrial assembly family protein
MHFBIMFO_01873 1.6e-185 NU COG4972 Tfp pilus assembly protein, ATPase PilM
MHFBIMFO_01874 8.9e-56 NU cell adhesion
MHFBIMFO_01876 1.8e-202 pilC NU type II secretion system
MHFBIMFO_01877 2.4e-195 pilT NU twitching motility protein
MHFBIMFO_01878 1.2e-294 pilB NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MHFBIMFO_01879 9.1e-214 V G5
MHFBIMFO_01880 2.3e-128 S PRC-barrel domain
MHFBIMFO_01881 5e-232
MHFBIMFO_01882 3.1e-226 NU Pilus assembly protein PilX
MHFBIMFO_01883 6.7e-87
MHFBIMFO_01885 2.7e-252 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MHFBIMFO_01886 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHFBIMFO_01887 3e-27
MHFBIMFO_01888 2.4e-192 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MHFBIMFO_01889 4.3e-217 spoVID M stage VI sporulation protein D
MHFBIMFO_01890 3.5e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MHFBIMFO_01891 7.1e-186 hemB 4.2.1.24 H Belongs to the ALAD family
MHFBIMFO_01892 1.8e-147 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MHFBIMFO_01893 2.9e-168 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MHFBIMFO_01894 1.3e-148 hemX O cytochrome C
MHFBIMFO_01895 5.6e-242 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MHFBIMFO_01896 4.5e-88 ysxD
MHFBIMFO_01897 4.4e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MHFBIMFO_01898 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MHFBIMFO_01899 2.7e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MHFBIMFO_01900 6.3e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHFBIMFO_01901 8.4e-211 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHFBIMFO_01902 1.4e-184 trxA2 O COG0457 FOG TPR repeat
MHFBIMFO_01903 1.1e-72 S Protein of unknown function (DUF2512)
MHFBIMFO_01904 1.5e-46
MHFBIMFO_01906 2.8e-93 ysnB S Phosphoesterase
MHFBIMFO_01907 5.9e-106 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHFBIMFO_01908 4.6e-191 gerM S COG5401 Spore germination protein
MHFBIMFO_01909 7.9e-15
MHFBIMFO_01910 8.7e-42 M Spore coat protein
MHFBIMFO_01911 4.6e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHFBIMFO_01912 4.2e-62 yraF M Spore coat protein
MHFBIMFO_01913 4.9e-31 yraG S Spore Coat Protein
MHFBIMFO_01914 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MHFBIMFO_01915 3.9e-78 ysmB 2.4.2.28 K transcriptional
MHFBIMFO_01916 3.8e-93 S GDYXXLXY protein
MHFBIMFO_01917 4.2e-195 S Predicted membrane protein (DUF2157)
MHFBIMFO_01919 2.3e-31 gerE K Transcriptional regulator
MHFBIMFO_01920 2.3e-89 ysmA S thioesterase
MHFBIMFO_01921 2.9e-150 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MHFBIMFO_01922 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MHFBIMFO_01923 2.5e-104 sdhC C succinate dehydrogenase
MHFBIMFO_01924 2.3e-78 yslB S Protein of unknown function (DUF2507)
MHFBIMFO_01925 2e-222 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MHFBIMFO_01926 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHFBIMFO_01927 5.1e-53 trxA O Belongs to the thioredoxin family
MHFBIMFO_01928 8.7e-176 etfA C Electron transfer flavoprotein
MHFBIMFO_01929 4.8e-129 etfB C Electron transfer flavoprotein
MHFBIMFO_01930 4e-139 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MHFBIMFO_01931 6e-103 fadR K Transcriptional regulator
MHFBIMFO_01932 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHFBIMFO_01933 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHFBIMFO_01934 0.0 polX L COG1796 DNA polymerase IV (family X)
MHFBIMFO_01935 6.4e-88 cvpA S membrane protein, required for colicin V production
MHFBIMFO_01936 7.3e-46 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHFBIMFO_01937 1.8e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHFBIMFO_01938 1.6e-171 S Nuclease-related domain
MHFBIMFO_01939 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHFBIMFO_01940 9.6e-181 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHFBIMFO_01941 8.9e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHFBIMFO_01942 7.5e-32 sspI S Belongs to the SspI family
MHFBIMFO_01943 2.3e-116
MHFBIMFO_01944 1.4e-32 sidE D nuclear chromosome segregation
MHFBIMFO_01945 1.1e-124 M1-1017 S Protein of unknown function (DUF1129)
MHFBIMFO_01946 1.8e-56 K Transcriptional regulator
MHFBIMFO_01947 2.3e-11 S NADPH-dependent FMN reductase
MHFBIMFO_01948 1.3e-127 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MHFBIMFO_01949 5.2e-178 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHFBIMFO_01950 1.1e-101 yieF S NAD(P)H-dependent FMN reductase
MHFBIMFO_01951 3.9e-98 ypdE 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHFBIMFO_01952 1.5e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MHFBIMFO_01954 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHFBIMFO_01955 4.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MHFBIMFO_01956 3.9e-108 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHFBIMFO_01957 8.4e-219 G Transmembrane secretion effector
MHFBIMFO_01958 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHFBIMFO_01959 1.4e-153 ytxC S YtxC-like family
MHFBIMFO_01960 1.4e-175 dnaI L Primosomal protein DnaI
MHFBIMFO_01961 1.9e-261 dnaB L Membrane attachment protein
MHFBIMFO_01962 2.1e-79 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHFBIMFO_01963 8.2e-90 2.3.1.178 J Benzoate transporter
MHFBIMFO_01964 5.8e-194 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHFBIMFO_01965 3.6e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHFBIMFO_01966 1.9e-107 ytaF P Probably functions as a manganese efflux pump
MHFBIMFO_01967 1.7e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHFBIMFO_01968 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHFBIMFO_01969 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MHFBIMFO_01970 4e-245 icd 1.1.1.42 C isocitrate
MHFBIMFO_01971 5.2e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
MHFBIMFO_01972 1e-73 yeaL S Membrane
MHFBIMFO_01973 1.7e-159 ytvI S sporulation integral membrane protein YtvI
MHFBIMFO_01974 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MHFBIMFO_01975 3.2e-178 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHFBIMFO_01976 1.1e-178 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MHFBIMFO_01977 6.2e-165 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHFBIMFO_01978 9.8e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MHFBIMFO_01979 0.0 dnaE 2.7.7.7 L DNA polymerase
MHFBIMFO_01980 1.6e-41 ytrH S Sporulation protein YtrH
MHFBIMFO_01981 2.1e-88 ytrI
MHFBIMFO_01982 1.9e-180 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MHFBIMFO_01983 1.2e-38 ytpI S YtpI-like protein
MHFBIMFO_01984 1e-240 ytoI K transcriptional regulator containing CBS domains
MHFBIMFO_01985 1.1e-129 ytkL S Belongs to the UPF0173 family
MHFBIMFO_01986 5e-180 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MHFBIMFO_01987 2.1e-202 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MHFBIMFO_01988 5.6e-80 uspA T Belongs to the universal stress protein A family
MHFBIMFO_01989 2.9e-156 S EcsC protein family
MHFBIMFO_01990 9.2e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHFBIMFO_01991 5.8e-175 ytxK 2.1.1.72 L DNA methylase
MHFBIMFO_01992 9.9e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHFBIMFO_01993 5.8e-69 ytfJ S Sporulation protein YtfJ
MHFBIMFO_01994 5.5e-121 ytfI S Protein of unknown function (DUF2953)
MHFBIMFO_01995 4.1e-87 yteJ S RDD family
MHFBIMFO_01996 1e-187 sppA OU signal peptide peptidase SppA
MHFBIMFO_01997 0.0 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHFBIMFO_01998 1.4e-27 sspB S spore protein
MHFBIMFO_01999 1.9e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHFBIMFO_02000 3.9e-215 iscS2 2.8.1.7 E Cysteine desulfurase
MHFBIMFO_02001 2.2e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHFBIMFO_02002 4.2e-118 yttP K Transcriptional regulator
MHFBIMFO_02003 7e-86 ytsP 1.8.4.14 T GAF domain-containing protein
MHFBIMFO_02004 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MHFBIMFO_02005 1.9e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHFBIMFO_02006 1.3e-145
MHFBIMFO_02007 2e-126
MHFBIMFO_02008 9.5e-186 putA E Proline dehydrogenase
MHFBIMFO_02009 7.6e-299 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHFBIMFO_02010 7e-256 prdR KT Transcriptional regulator
MHFBIMFO_02011 2.2e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHFBIMFO_02012 2.5e-152 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MHFBIMFO_02013 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
MHFBIMFO_02014 2e-89 yrhD S Protein of unknown function (DUF1641)
MHFBIMFO_02015 1.8e-192 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHFBIMFO_02016 2.7e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MHFBIMFO_02017 1.1e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MHFBIMFO_02018 1.2e-79 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MHFBIMFO_02019 1.3e-87 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MHFBIMFO_02020 3.7e-235 moeA 2.10.1.1 H molybdopterin
MHFBIMFO_02021 7.8e-123 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MHFBIMFO_02022 1.4e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MHFBIMFO_02023 7.2e-247 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MHFBIMFO_02024 2.5e-132 modC 3.6.3.29 P ATPases associated with a variety of cellular activities
MHFBIMFO_02025 2.6e-121 P COG4149 ABC-type molybdate transport system, permease component
MHFBIMFO_02026 5e-134 modA P Molybdenum ABC transporter
MHFBIMFO_02027 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHFBIMFO_02028 1.9e-123 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MHFBIMFO_02029 3.8e-119 acuB S Acetoin utilization protein AcuB
MHFBIMFO_02030 1.6e-232 acuC BQ histone deacetylase
MHFBIMFO_02031 1.7e-182 ccpA K catabolite control protein A
MHFBIMFO_02032 4.3e-192 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MHFBIMFO_02033 2.4e-36 XK27_07760 S COG4980 Gas vesicle protein
MHFBIMFO_02034 2.8e-51 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHFBIMFO_02035 1.4e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MHFBIMFO_02036 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MHFBIMFO_02037 8.2e-74 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHFBIMFO_02038 5.2e-110 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHFBIMFO_02039 4.8e-148 ytpQ S Belongs to the UPF0354 family
MHFBIMFO_02040 1.9e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MHFBIMFO_02041 1.7e-179 rsbU 3.1.3.3 T response regulator
MHFBIMFO_02042 4.8e-126 mcp64H-2 NT transmembrane signaling receptor activity
MHFBIMFO_02043 6.6e-53 ytzB S small secreted protein
MHFBIMFO_02044 1.5e-171 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MHFBIMFO_02046 5.1e-130 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHFBIMFO_02047 2.7e-55 ytzH S YtzH-like protein
MHFBIMFO_02048 7.3e-157 ytmP 2.7.1.89 M Phosphotransferase
MHFBIMFO_02050 4.8e-147 ytlQ
MHFBIMFO_02051 7.7e-108 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MHFBIMFO_02053 1.2e-160 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MHFBIMFO_02054 7e-275 pepV 3.5.1.18 E Dipeptidase
MHFBIMFO_02055 2.7e-32 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MHFBIMFO_02056 1.2e-286 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHFBIMFO_02057 6.4e-27 yteV S Sporulation protein Cse60
MHFBIMFO_02058 2.3e-10
MHFBIMFO_02060 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHFBIMFO_02061 1.6e-187 yttB EGP Major facilitator Superfamily
MHFBIMFO_02062 9.4e-43 ytzC S Protein of unknown function (DUF2524)
MHFBIMFO_02064 8e-105 ytqB J Putative rRNA methylase
MHFBIMFO_02065 5.7e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MHFBIMFO_02066 1.2e-154 ytpA 3.1.1.5 I Alpha beta hydrolase
MHFBIMFO_02067 5.6e-73 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MHFBIMFO_02068 0.0 asnB 6.3.5.4 E Asparagine synthase
MHFBIMFO_02069 2.9e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHFBIMFO_02070 0.0 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MHFBIMFO_02071 3.7e-69 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
MHFBIMFO_02073 1.4e-208 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MHFBIMFO_02074 2.3e-101 ywqN S NAD(P)H-dependent
MHFBIMFO_02075 5.2e-192 gntK 2.7.1.12, 2.7.1.17 G FGGY family of carbohydrate kinases, N-terminal domain
MHFBIMFO_02076 2e-70 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MHFBIMFO_02077 1.7e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHFBIMFO_02078 1e-139 ytlC P ABC transporter
MHFBIMFO_02079 1.5e-128 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHFBIMFO_02080 2e-85 ytkD 3.6.1.55 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHFBIMFO_02081 7.4e-39
MHFBIMFO_02082 2.5e-77 dps P Belongs to the Dps family
MHFBIMFO_02083 1.3e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MHFBIMFO_02085 6.1e-160 adcA P Belongs to the bacterial solute-binding protein 9 family
MHFBIMFO_02086 2.1e-23 S Domain of Unknown Function (DUF1540)
MHFBIMFO_02087 4.7e-210 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MHFBIMFO_02088 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MHFBIMFO_02089 1.9e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MHFBIMFO_02090 9.1e-155 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MHFBIMFO_02091 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MHFBIMFO_02092 9.6e-258 menF 5.4.4.2 HQ Isochorismate synthase
MHFBIMFO_02093 1.6e-163 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MHFBIMFO_02103 3e-09
MHFBIMFO_02109 5.1e-08
MHFBIMFO_02110 1.6e-08
MHFBIMFO_02114 5.3e-43
MHFBIMFO_02115 4.3e-42 S COG NOG14552 non supervised orthologous group
MHFBIMFO_02116 4.4e-29 K Helix-turn-helix XRE-family like proteins
MHFBIMFO_02118 9.2e-233 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
MHFBIMFO_02119 2.2e-26
MHFBIMFO_02120 7.1e-156 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHFBIMFO_02121 5.5e-116 sapB S MgtC SapB transporter
MHFBIMFO_02122 6.2e-167 S Protein of unknown function (DUF1646)
MHFBIMFO_02123 1.2e-59 EGP Major facilitator Superfamily
MHFBIMFO_02124 0.0 copA 3.6.3.54 P P-type ATPase
MHFBIMFO_02125 2.4e-30 P Copper resistance protein CopZ
MHFBIMFO_02126 8.4e-57 S protein conserved in bacteria
MHFBIMFO_02127 5.1e-69 lrpC K Transcriptional regulator
MHFBIMFO_02128 1.1e-71 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHFBIMFO_02129 2.5e-225 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MHFBIMFO_02130 1.3e-27 yhjC S Protein of unknown function (DUF3311)
MHFBIMFO_02131 5.5e-267 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHFBIMFO_02133 7e-13 yhjQ C COG1145 Ferredoxin
MHFBIMFO_02134 3.1e-33 S Protein of unknown function (DUF2933)
MHFBIMFO_02136 3.8e-249 T PhoQ Sensor
MHFBIMFO_02137 2.3e-127 KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHFBIMFO_02138 4.9e-91 ydhK M Protein of unknown function (DUF1541)
MHFBIMFO_02139 3e-87 VY92_08700 S Enoyl-(Acyl carrier protein) reductase
MHFBIMFO_02140 5.4e-12 recN L Putative cell-wall binding lipoprotein
MHFBIMFO_02141 4.1e-175 nodB1 G deacetylase
MHFBIMFO_02144 5.4e-245 P Voltage gated chloride channel
MHFBIMFO_02145 1.5e-49 P Rhodanese domain protein
MHFBIMFO_02146 1.9e-37 yhjE S protein conserved in bacteria
MHFBIMFO_02147 8e-148 yokF 3.1.31.1 L RNA catabolic process
MHFBIMFO_02148 5e-74 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MHFBIMFO_02149 3.7e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MHFBIMFO_02150 2.7e-131 araD 4.1.2.17, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MHFBIMFO_02151 2.7e-255 araP EGP Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHFBIMFO_02152 1.9e-305 araB 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MHFBIMFO_02153 1.3e-215 araR K transcriptional
MHFBIMFO_02154 4e-239 NT chemotaxis protein
MHFBIMFO_02155 1.3e-128 plsB 2.3.1.15 I Acyl-transferase
MHFBIMFO_02156 8.5e-204 2.4.1.83 GT2 M Glycosyl transferase family 2
MHFBIMFO_02157 9.9e-122 IQ Enoyl-(Acyl carrier protein) reductase
MHFBIMFO_02158 9.6e-72 yuiD S protein conserved in bacteria
MHFBIMFO_02159 1e-223 solA 1.5.3.1 E FAD dependent oxidoreductase
MHFBIMFO_02160 2e-227 FOXRED 1.5.3.1 E FAD dependent oxidoreductase
MHFBIMFO_02161 8.8e-281 ycbD 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHFBIMFO_02162 1.4e-170 4.3.1.12 E ornithine cyclodeaminase
MHFBIMFO_02165 1.7e-182 yugO P COG1226 Kef-type K transport systems
MHFBIMFO_02166 1.3e-259 pgi 5.3.1.9 G Belongs to the GPI family
MHFBIMFO_02167 5.1e-34 yuzA S Domain of unknown function (DUF378)
MHFBIMFO_02168 4.8e-87 K Bacterial transcription activator, effector binding domain
MHFBIMFO_02169 1.2e-64 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MHFBIMFO_02170 3.4e-29 K Helix-turn-helix XRE-family like proteins
MHFBIMFO_02171 4.2e-197 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MHFBIMFO_02172 1.2e-165 S reductase
MHFBIMFO_02173 9.9e-160 dkgB S Aldo/keto reductase family
MHFBIMFO_02174 5.4e-239 S protein conserved in bacteria
MHFBIMFO_02176 2.7e-111 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHFBIMFO_02177 1.5e-67 kapB G Kinase associated protein B
MHFBIMFO_02178 3e-194 yuxJ EGP Major facilitator Superfamily
MHFBIMFO_02179 9.4e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
MHFBIMFO_02180 2.2e-55 yuzC
MHFBIMFO_02182 2.2e-199 E Spore germination protein
MHFBIMFO_02183 5.1e-234 gerKC S spore germination
MHFBIMFO_02184 1.3e-304 gerKA EG Spore germination protein
MHFBIMFO_02186 0.0 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MHFBIMFO_02187 6.4e-108 yuiC S protein conserved in bacteria
MHFBIMFO_02188 1.2e-46 yuiB S Putative membrane protein
MHFBIMFO_02189 1.1e-231 yumB 1.6.99.3 C NADH dehydrogenase
MHFBIMFO_02190 3.3e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
MHFBIMFO_02191 2.2e-63 erpA S Belongs to the HesB IscA family
MHFBIMFO_02192 1.1e-59 yuzD S protein conserved in bacteria
MHFBIMFO_02193 8.6e-37 nifU O COG0694 Thioredoxin-like proteins and domains
MHFBIMFO_02194 2.8e-201 yutH S Spore coat protein
MHFBIMFO_02195 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MHFBIMFO_02196 6.7e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHFBIMFO_02197 1.9e-74 yutE S Protein of unknown function DUF86
MHFBIMFO_02198 1.5e-48 yutD S protein conserved in bacteria
MHFBIMFO_02199 1e-173 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MHFBIMFO_02200 6.7e-200 lytH M Peptidase, M23
MHFBIMFO_02201 1.9e-127 yunB S Sporulation protein YunB (Spo_YunB)
MHFBIMFO_02202 5.3e-47 yunC S Domain of unknown function (DUF1805)
MHFBIMFO_02203 9.7e-285 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MHFBIMFO_02204 2.2e-273 sufB O FeS cluster assembly
MHFBIMFO_02205 7.9e-76 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MHFBIMFO_02206 5.9e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHFBIMFO_02207 2.5e-242 sufD O assembly protein SufD
MHFBIMFO_02208 3.5e-143 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MHFBIMFO_02210 9.5e-52 traF CO Thioredoxin
MHFBIMFO_02211 4.9e-66 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MHFBIMFO_02212 7.4e-64 arsC 1.20.4.1 P Belongs to the ArsC family
MHFBIMFO_02213 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MHFBIMFO_02214 1e-215 fadA 2.3.1.16 I Belongs to the thiolase family
MHFBIMFO_02215 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MHFBIMFO_02216 2.6e-14 S YuzL-like protein
MHFBIMFO_02217 2.4e-40
MHFBIMFO_02218 7.1e-56 yusN M Coat F domain
MHFBIMFO_02219 7.5e-217 rodA D Belongs to the SEDS family
MHFBIMFO_02220 5.7e-70 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MHFBIMFO_02221 2.4e-283 cls2 I PLD-like domain
MHFBIMFO_02223 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MHFBIMFO_02224 6.5e-273 L RNA-directed DNA polymerase (reverse transcriptase)
MHFBIMFO_02225 5.2e-195 M1-600 T Putative diguanylate phosphodiesterase
MHFBIMFO_02226 7e-302 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MHFBIMFO_02227 1.1e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MHFBIMFO_02228 2.9e-139 pgdA 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
MHFBIMFO_02229 2.1e-246 ugtP 2.4.1.315 GT28 M Monogalactosyldiacylglycerol (MGDG) synthase
MHFBIMFO_02230 1.5e-131
MHFBIMFO_02231 2.5e-86 S Putative zinc-finger
MHFBIMFO_02232 3e-93 K Belongs to the sigma-70 factor family. ECF subfamily
MHFBIMFO_02233 8.2e-221 ykoN 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MHFBIMFO_02234 0.0 M Dolichyl-phosphate-mannose-protein mannosyltransferase
MHFBIMFO_02235 7.6e-38 NU cell adhesion
MHFBIMFO_02236 1.5e-135 L Transposase IS4 family protein
MHFBIMFO_02237 1.3e-63 L Transposase IS4 family protein
MHFBIMFO_02238 1e-123 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHFBIMFO_02239 1.4e-98 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHFBIMFO_02241 6.3e-18
MHFBIMFO_02242 1e-198 L DDE superfamily endonuclease
MHFBIMFO_02243 2.1e-19
MHFBIMFO_02244 2e-191 L Transposase
MHFBIMFO_02245 5.7e-10 S transposase or invertase
MHFBIMFO_02246 5e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MHFBIMFO_02247 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHFBIMFO_02248 3.4e-143 est 3.1.1.1 S Carboxylesterase
MHFBIMFO_02249 2.5e-28 secG U Preprotein translocase subunit SecG
MHFBIMFO_02250 5.4e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHFBIMFO_02252 3.8e-303 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MHFBIMFO_02253 1.1e-122 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHFBIMFO_02254 8.3e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MHFBIMFO_02255 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHFBIMFO_02256 1.5e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHFBIMFO_02257 7e-41 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MHFBIMFO_02258 1.9e-245 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MHFBIMFO_02260 1.3e-07 S Heavy-metal-associated domain
MHFBIMFO_02261 2.2e-85 S Protein of unknown function (DUF1641)
MHFBIMFO_02263 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
MHFBIMFO_02264 1.7e-31
MHFBIMFO_02266 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHFBIMFO_02267 5.3e-84 uspF T Universal stress protein
MHFBIMFO_02269 1.3e-193 ykfD E Belongs to the ABC transporter superfamily
MHFBIMFO_02270 1e-178 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHFBIMFO_02271 0.0 dppE E ABC transporter substrate-binding protein
MHFBIMFO_02272 1.1e-189 dppD P Belongs to the ABC transporter superfamily
MHFBIMFO_02273 4.1e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHFBIMFO_02274 7.5e-161 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHFBIMFO_02275 4.7e-131 S Peptidase C26
MHFBIMFO_02276 7.7e-185 corA P Mediates influx of magnesium ions
MHFBIMFO_02277 1.8e-46 yhdB S YhdB-like protein
MHFBIMFO_02279 1.4e-280 ycgB S Stage V sporulation protein R
MHFBIMFO_02280 9.4e-186 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MHFBIMFO_02281 6.3e-136 3.2.1.18 GH33 E GDSL-like Lipase/Acylhydrolase
MHFBIMFO_02282 1.2e-73 bdbC O Required for disulfide bond formation in some proteins
MHFBIMFO_02283 5.8e-88 bdbA CO Thioredoxin
MHFBIMFO_02284 3.5e-67 yhcU S Family of unknown function (DUF5365)
MHFBIMFO_02285 1.2e-10 yhcU S Family of unknown function (DUF5365)
MHFBIMFO_02286 5.6e-112 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MHFBIMFO_02287 2.5e-178 pit P phosphate transporter
MHFBIMFO_02288 2.5e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
MHFBIMFO_02290 9.6e-222 yhbH S Belongs to the UPF0229 family
MHFBIMFO_02291 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
MHFBIMFO_02292 0.0 prkA T Ser protein kinase
MHFBIMFO_02293 2e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHFBIMFO_02294 1e-162 yhbB S Putative amidase domain
MHFBIMFO_02295 1.2e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MHFBIMFO_02296 3.7e-103 yvbG U UPF0056 membrane protein
MHFBIMFO_02297 9.1e-98 L Transposase
MHFBIMFO_02298 1.6e-166 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MHFBIMFO_02299 1.3e-84 S Rubrerythrin
MHFBIMFO_02300 2.2e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MHFBIMFO_02301 1.4e-116 tcyB P COG0765 ABC-type amino acid transport system, permease component
MHFBIMFO_02302 2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHFBIMFO_02303 1.2e-149 focA P Formate/nitrite transporter
MHFBIMFO_02304 7.6e-07 S Protein of unknown function (DUF2705)
MHFBIMFO_02306 0.0 pflB 2.3.1.54 C formate acetyltransferase
MHFBIMFO_02307 7.1e-146 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHFBIMFO_02308 3.3e-95 1.5.1.38 S FMN reductase
MHFBIMFO_02309 6.4e-88
MHFBIMFO_02310 5.7e-175 bcrB S ABC transporter (permease)
MHFBIMFO_02311 5.6e-169 bcrA V ABC transporter, ATP-binding protein
MHFBIMFO_02312 6.3e-132 ypmR1 E G-D-S-L family
MHFBIMFO_02313 5.5e-74 P Domain of unknown function (DUF2935)
MHFBIMFO_02315 2.8e-171 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MHFBIMFO_02316 2.8e-126
MHFBIMFO_02317 1.2e-241 L Transposase IS4 family protein
MHFBIMFO_02320 7.6e-191 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHFBIMFO_02321 1.7e-199 adhC 1.1.1.1 C Zinc-binding dehydrogenase
MHFBIMFO_02324 1.6e-08
MHFBIMFO_02328 8.7e-08
MHFBIMFO_02329 1.7e-07
MHFBIMFO_02337 5.3e-43
MHFBIMFO_02338 4.3e-42 S COG NOG14552 non supervised orthologous group
MHFBIMFO_02339 2.3e-164 ygxA S Nucleotidyltransferase-like
MHFBIMFO_02340 3.5e-58 ygzB S UPF0295 protein
MHFBIMFO_02341 1e-139 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MHFBIMFO_02342 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MHFBIMFO_02343 1.5e-163 alsR K Transcriptional regulator
MHFBIMFO_02344 3.2e-89 iprA K Transcriptional regulator
MHFBIMFO_02346 9.8e-82 perR P Belongs to the Fur family
MHFBIMFO_02347 9.9e-205 L PFAM Transposase_11
MHFBIMFO_02348 1.4e-101 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
MHFBIMFO_02350 3.4e-65 P Ion transport
MHFBIMFO_02351 1.1e-247 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MHFBIMFO_02352 6.2e-63 yitG EGP Major facilitator Superfamily
MHFBIMFO_02353 6.7e-16 yitG EGP Major facilitator Superfamily
MHFBIMFO_02354 2.7e-64
MHFBIMFO_02355 8.2e-39 yqhV S Protein of unknown function (DUF2619)
MHFBIMFO_02356 1.7e-188 ygaE S Membrane
MHFBIMFO_02357 1.2e-155 K transcriptional
MHFBIMFO_02358 1.6e-250 sacX 2.7.1.201, 2.7.1.211 G phosphotransferase system
MHFBIMFO_02359 5.3e-156 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHFBIMFO_02360 1.3e-212 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MHFBIMFO_02361 0.0 ygaD V ABC transporter
MHFBIMFO_02362 4.1e-103 ygaC J Belongs to the UPF0374 family
MHFBIMFO_02363 6e-36 ygaB S YgaB-like protein
MHFBIMFO_02364 5.1e-10 sspE S Small, acid-soluble spore protein, gamma-type
MHFBIMFO_02365 7.7e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHFBIMFO_02366 3.4e-166 gltC K Transcriptional regulator
MHFBIMFO_02367 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MHFBIMFO_02369 8.7e-289 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MHFBIMFO_02370 8.1e-233 L Transposase, IS4 family protein
MHFBIMFO_02371 5.4e-33 S hydrolase
MHFBIMFO_02372 2e-230 L Transposase IS4 family protein
MHFBIMFO_02373 1.5e-21 sspK S reproduction
MHFBIMFO_02374 3.8e-187 yfhP S membrane-bound metal-dependent
MHFBIMFO_02375 3.4e-208 mutY L A G-specific
MHFBIMFO_02376 2.2e-51 yfhH S Protein of unknown function (DUF1811)
MHFBIMFO_02377 5.1e-145 recX 2.4.1.337 GT4 S Modulates RecA activity
MHFBIMFO_02379 2.9e-24 yfhD S YfhD-like protein
MHFBIMFO_02380 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHFBIMFO_02382 1.8e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHFBIMFO_02383 4.4e-261 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
MHFBIMFO_02384 1.4e-184 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHFBIMFO_02385 1.9e-109 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MHFBIMFO_02386 4.9e-265 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHFBIMFO_02387 1.3e-48 bacI V COG0577 ABC-type antimicrobial peptide transport system, permease component
MHFBIMFO_02388 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHFBIMFO_02389 5.4e-83 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHFBIMFO_02391 8.3e-250 mcpA NT chemotaxis protein
MHFBIMFO_02392 1.3e-184 serA1 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHFBIMFO_02393 4e-220 dhsS 1.12.1.2 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MHFBIMFO_02394 1.5e-302 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHFBIMFO_02395 1.7e-177 S Phosphotransferase system, EIIC
MHFBIMFO_02396 2.7e-221 2.6.1.9 S HAD-hyrolase-like
MHFBIMFO_02397 8.2e-188 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHFBIMFO_02398 7.8e-111 leuD 4.2.1.33, 4.2.1.35, 4.2.1.36 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHFBIMFO_02399 7e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHFBIMFO_02400 1e-204 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MHFBIMFO_02401 3e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MHFBIMFO_02402 4.7e-196 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHFBIMFO_02403 1.1e-84 ilvN 2.2.1.6 E Acetolactate synthase
MHFBIMFO_02404 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MHFBIMFO_02405 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MHFBIMFO_02406 5.5e-245 braB E Component of the transport system for branched-chain amino acids
MHFBIMFO_02407 3.7e-154 T STAS domain
MHFBIMFO_02408 2.1e-246
MHFBIMFO_02410 7.4e-100 L Transposase
MHFBIMFO_02411 1.1e-15 S Ribbon-helix-helix protein, copG family
MHFBIMFO_02412 1.4e-56 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MHFBIMFO_02413 2.6e-104 yetJ S Belongs to the BI1 family
MHFBIMFO_02414 4.7e-218 yxjG 2.1.1.14 E Methionine synthase
MHFBIMFO_02415 3.3e-220 yhjX P Major facilitator superfamily
MHFBIMFO_02416 9.7e-100 L Transposase
MHFBIMFO_02417 1.2e-48 L Transposase
MHFBIMFO_02418 1.1e-15 S Ribbon-helix-helix protein, copG family
MHFBIMFO_02419 1.9e-138 ypdB KT LytTr DNA-binding domain
MHFBIMFO_02420 4.4e-308 ypdA 2.7.13.3 T Signal transduction histidine kinase
MHFBIMFO_02421 7.2e-194 ansA 3.5.1.1 EJ L-asparaginase
MHFBIMFO_02422 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MHFBIMFO_02423 8.8e-107 yhgD K Transcriptional regulator
MHFBIMFO_02424 3e-296 yhgE S YhgE Pip N-terminal domain protein
MHFBIMFO_02425 2e-252 S Protein of unknown function N-terminus (DUF3323)
MHFBIMFO_02426 0.0 D Putative exonuclease SbcCD, C subunit
MHFBIMFO_02427 3e-231 S Protein of unknown function (DUF2398)
MHFBIMFO_02429 1.3e-260 S Protein of unknown function (DUF2397)
MHFBIMFO_02430 5.6e-43
MHFBIMFO_02431 5.6e-237 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHFBIMFO_02432 5.1e-76 yqgC S protein conserved in bacteria
MHFBIMFO_02433 9.4e-275 ydbT S Bacterial PH domain
MHFBIMFO_02434 3.2e-86 S Bacterial PH domain
MHFBIMFO_02435 3.9e-87 S AAA domain
MHFBIMFO_02436 4.3e-32 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MHFBIMFO_02437 6.8e-262 proP EGP Transporter
MHFBIMFO_02438 8.7e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHFBIMFO_02439 2e-56 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHFBIMFO_02440 7.7e-100 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHFBIMFO_02441 4.7e-35 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHFBIMFO_02442 1e-128 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MHFBIMFO_02443 2.3e-187 2.3.1.180 I 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III
MHFBIMFO_02444 7.9e-58
MHFBIMFO_02446 5.6e-250 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MHFBIMFO_02449 1.3e-307 lmrA 3.6.3.44 V ABC transporter
MHFBIMFO_02450 6.7e-102 K DNA-binding transcription factor activity
MHFBIMFO_02451 9.7e-91 cca 2.7.7.19, 2.7.7.72 J Aminoglycoside-2''-adenylyltransferase
MHFBIMFO_02452 4.8e-100
MHFBIMFO_02453 7.3e-49
MHFBIMFO_02454 5.5e-86 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHFBIMFO_02455 4.3e-152 rumA 2.1.1.190, 2.1.1.35 J TRAM domain
MHFBIMFO_02456 4.5e-168 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MHFBIMFO_02457 7.3e-149 pdaA G deacetylase
MHFBIMFO_02458 3e-27 yfjT
MHFBIMFO_02459 3.7e-148 yfkD S YfkD-like protein
MHFBIMFO_02460 4e-174 cax P COG0387 Ca2 H antiporter
MHFBIMFO_02461 4.8e-221 yfkF EGP Major facilitator Superfamily
MHFBIMFO_02462 5.4e-150 yihY S Belongs to the UPF0761 family
MHFBIMFO_02463 7.3e-33 yfkK S Belongs to the UPF0435 family
MHFBIMFO_02464 3e-144 map 3.4.11.18 E Methionine aminopeptidase
MHFBIMFO_02465 1.6e-91 yfkM 3.5.1.124 S protease
MHFBIMFO_02466 1.9e-139 motB N Flagellar motor protein
MHFBIMFO_02467 6.6e-137 motA N flagellar motor
MHFBIMFO_02468 1.6e-58 yhdN S Domain of unknown function (DUF1992)
MHFBIMFO_02470 2.2e-60 yeaO S Protein of unknown function, DUF488
MHFBIMFO_02471 1e-229 EGP Major facilitator Superfamily
MHFBIMFO_02472 8.7e-147 dksA T COG1734 DnaK suppressor protein
MHFBIMFO_02473 1.3e-85 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MHFBIMFO_02474 2.6e-183 mreB D Rod-share determining protein MreBH
MHFBIMFO_02475 2.6e-171 yuaG S protein conserved in bacteria
MHFBIMFO_02476 2.5e-90 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MHFBIMFO_02477 1e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHFBIMFO_02478 1.8e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MHFBIMFO_02479 6.2e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHFBIMFO_02480 5.4e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MHFBIMFO_02481 2.8e-102 4.2.1.1 P Reversible hydration of carbon dioxide
MHFBIMFO_02482 4.5e-118 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MHFBIMFO_02485 8e-293 K helix_turn_helix, Lux Regulon
MHFBIMFO_02486 1.2e-106 che
MHFBIMFO_02487 3.1e-69 S response to pH
MHFBIMFO_02488 1.8e-114
MHFBIMFO_02489 2.6e-145 ypuA S Secreted protein
MHFBIMFO_02490 8.2e-154 K RpiR family transcriptional regulator
MHFBIMFO_02491 2.2e-223 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MHFBIMFO_02492 4.2e-226 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHFBIMFO_02493 2e-117 cobC 3.1.3.3, 3.1.3.73, 5.4.2.12 G Histidine phosphatase superfamily (branch 1)
MHFBIMFO_02494 2.3e-72 K sequence-specific DNA binding
MHFBIMFO_02496 1.9e-71 L COG2801 Transposase and inactivated derivatives
MHFBIMFO_02497 6.9e-71 L COG2801 Transposase and inactivated derivatives
MHFBIMFO_02498 1.6e-45 L COG2963 Transposase and inactivated derivatives
MHFBIMFO_02499 3.3e-172 L Transposase DDE domain
MHFBIMFO_02500 1.8e-28 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHFBIMFO_02501 3.2e-189 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHFBIMFO_02502 1.1e-70 cas4 3.1.12.1 L Domain of unknown function DUF83
MHFBIMFO_02503 0.0 cas3 L CRISPR-associated helicase, Cas3
MHFBIMFO_02504 6.1e-145 cas5h S CRISPR-associated protein Cas5
MHFBIMFO_02505 4.1e-178 L CRISPR-associated protein Cas7
MHFBIMFO_02506 0.0 csh
MHFBIMFO_02507 1.4e-127 cas6 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA)
MHFBIMFO_02508 0.0 snf 2.7.11.1 L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHFBIMFO_02509 6.5e-110 C Nitroreductase family
MHFBIMFO_02510 2.4e-89 1.8.5.2 S DoxX
MHFBIMFO_02512 1.2e-210 fni 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHFBIMFO_02513 2.3e-119 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MHFBIMFO_02514 6e-35 yoeD G Helix-turn-helix domain
MHFBIMFO_02515 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MHFBIMFO_02516 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHFBIMFO_02517 1.1e-133 fruR K Transcriptional regulator
MHFBIMFO_02518 3.5e-205 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
MHFBIMFO_02519 3.2e-95 D Hemerythrin HHE cation binding
MHFBIMFO_02520 0.0 XK27_08510 L Type III restriction protein res subunit
MHFBIMFO_02521 8.2e-32
MHFBIMFO_02522 3.9e-153 yidA S hydrolases of the HAD superfamily
MHFBIMFO_02523 3.5e-57 ygbA S Nitrous oxide-stimulated promoter
MHFBIMFO_02524 7.8e-85 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MHFBIMFO_02525 4.3e-254 iolT EGP Major facilitator Superfamily
MHFBIMFO_02526 2.2e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MHFBIMFO_02528 1.3e-70 ywnF S Family of unknown function (DUF5392)
MHFBIMFO_02529 8.1e-137 ywaC 2.7.6.5 S protein conserved in bacteria
MHFBIMFO_02530 5.9e-255 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHFBIMFO_02531 1.1e-191 yhdN C Aldo keto reductase
MHFBIMFO_02532 2.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
MHFBIMFO_02533 5.6e-101 dhaL 2.7.1.121 S Dak2
MHFBIMFO_02534 2.3e-184 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
MHFBIMFO_02535 7.8e-175 pfoS S Phosphotransferase system, EIIC
MHFBIMFO_02536 1.8e-111 ureH S PFAM Nickel cobalt transporter, high-affinity
MHFBIMFO_02537 6.9e-158 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MHFBIMFO_02538 7.3e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MHFBIMFO_02539 3.3e-105 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MHFBIMFO_02540 6e-79 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MHFBIMFO_02541 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MHFBIMFO_02542 6.7e-56 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MHFBIMFO_02543 3.4e-48 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MHFBIMFO_02544 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
MHFBIMFO_02546 3.6e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MHFBIMFO_02547 7.1e-261 L Transposase DDE domain group 1
MHFBIMFO_02548 3e-248 L PFAM Transposase, IS4-like
MHFBIMFO_02549 7.9e-224 L PFAM Transposase, IS4-like
MHFBIMFO_02550 1.9e-258 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
MHFBIMFO_02551 8.4e-142 S Type II restriction endonuclease EcoO109I
MHFBIMFO_02552 1.2e-196 pepP 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MHFBIMFO_02553 7e-267 S PFAM Uncharacterised protein family UPF0236
MHFBIMFO_02554 8.1e-241 E COG1113 Gamma-aminobutyrate permease and related permeases
MHFBIMFO_02555 1.1e-167 ytnM S membrane transporter protein
MHFBIMFO_02556 7.2e-280 L Transposase
MHFBIMFO_02557 1.8e-203 L PFAM Transposase_11
MHFBIMFO_02558 1.8e-229 ywdJ F Xanthine uracil
MHFBIMFO_02559 0.0 yjcD 3.6.4.12 L DNA helicase
MHFBIMFO_02560 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHFBIMFO_02562 7.2e-98 O HI0933-like protein
MHFBIMFO_02563 1.8e-80 K Acetyltransferase (GNAT) domain
MHFBIMFO_02564 4.8e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MHFBIMFO_02565 5.5e-56 S PFAM Uncharacterised protein family UPF0236
MHFBIMFO_02566 6.7e-198 S PFAM Uncharacterised protein family UPF0236
MHFBIMFO_02567 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
MHFBIMFO_02568 2.4e-93 lysP E amino acid
MHFBIMFO_02569 1.3e-128 lysP E amino acid
MHFBIMFO_02570 3.4e-115 K Transcriptional regulator
MHFBIMFO_02571 2.8e-208 ybhR V COG0842 ABC-type multidrug transport system, permease component
MHFBIMFO_02573 9.8e-132 V COG1131 ABC-type multidrug transport system, ATPase component
MHFBIMFO_02574 6.1e-70 S Hemerythrin HHE cation binding domain
MHFBIMFO_02575 2.5e-52
MHFBIMFO_02576 4.1e-43
MHFBIMFO_02577 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHFBIMFO_02578 1.4e-107 narT P COG2223 Nitrate nitrite transporter
MHFBIMFO_02579 1.2e-163 fda 4.1.2.13 G Belongs to the class I fructose-bisphosphate aldolase family
MHFBIMFO_02580 3e-27
MHFBIMFO_02581 4.2e-52
MHFBIMFO_02584 2.8e-35 galM 5.1.3.3 G Aldose 1-epimerase
MHFBIMFO_02585 4.4e-117 galM 5.1.3.3 G Aldose 1-epimerase
MHFBIMFO_02586 0.0 katE 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MHFBIMFO_02589 0.0 S LXG domain of WXG superfamily
MHFBIMFO_02590 2.1e-88
MHFBIMFO_02591 6.4e-208 D SMC domain-containing protein
MHFBIMFO_02593 0.0 L HKD family nuclease
MHFBIMFO_02594 8.4e-53 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHFBIMFO_02595 3.9e-170 mrr V Mrr N-terminal domain
MHFBIMFO_02596 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MHFBIMFO_02597 7.2e-225 3.1.21.3 V Type I restriction modification DNA specificity domain
MHFBIMFO_02598 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
MHFBIMFO_02599 4e-27
MHFBIMFO_02600 9.7e-115 E LysE type translocator
MHFBIMFO_02601 1.8e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MHFBIMFO_02602 8.2e-82 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MHFBIMFO_02603 1.7e-157 3.2.1.122, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHFBIMFO_02604 1e-184 L PFAM Transposase, IS4-like
MHFBIMFO_02605 3e-118 S YqcI/YcgG family
MHFBIMFO_02606 2.5e-98 L Integrase
MHFBIMFO_02607 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MHFBIMFO_02608 1.1e-62 K transcriptional
MHFBIMFO_02609 1.3e-165 mleR K LysR substrate binding domain
MHFBIMFO_02610 3.6e-90 nrdG 1.97.1.4 O 4Fe-4S single cluster domain
MHFBIMFO_02611 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MHFBIMFO_02612 2.8e-207 U protein localization to endoplasmic reticulum
MHFBIMFO_02613 2.2e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MHFBIMFO_02614 8e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MHFBIMFO_02615 1.1e-141 L Transposase
MHFBIMFO_02616 5.3e-63 L Transposase
MHFBIMFO_02617 1.1e-15 S Ribbon-helix-helix protein, copG family
MHFBIMFO_02618 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MHFBIMFO_02619 6.1e-150 rbsC G Belongs to the binding-protein-dependent transport system permease family
MHFBIMFO_02620 6.9e-281 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHFBIMFO_02621 1.4e-68 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHFBIMFO_02622 1.1e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHFBIMFO_02623 2e-244 rbsR K transcriptional
MHFBIMFO_02624 1.6e-19 S transposase or invertase
MHFBIMFO_02625 5e-65 S transposase or invertase
MHFBIMFO_02626 6.9e-54 S transposase or invertase
MHFBIMFO_02628 6.5e-273 L RNA-directed DNA polymerase (reverse transcriptase)
MHFBIMFO_02629 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MHFBIMFO_02630 0.0 yfiB V ABC transporter
MHFBIMFO_02631 2.5e-80 K helix_turn_helix multiple antibiotic resistance protein
MHFBIMFO_02632 2.4e-102 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MHFBIMFO_02633 1.8e-103 P Integral membrane protein TerC family
MHFBIMFO_02634 1.5e-30 S Domain of unknown function (DUF202)
MHFBIMFO_02636 2.1e-80 XK27_04815 S Membrane transport protein
MHFBIMFO_02637 9e-56 XK27_04815 S Membrane transport protein
MHFBIMFO_02638 3.5e-304 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHFBIMFO_02639 3.5e-22 S Uncharacterized small protein (DUF2292)
MHFBIMFO_02640 5.8e-97 ssuE 1.5.1.38 S FMN reductase
MHFBIMFO_02641 2.5e-138 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
MHFBIMFO_02642 2e-135 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHFBIMFO_02643 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MHFBIMFO_02644 8.8e-168 P ABC transporter substrate-binding protein
MHFBIMFO_02645 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHFBIMFO_02646 1.8e-81 S SMI1-KNR4 cell-wall
MHFBIMFO_02647 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHFBIMFO_02648 4e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MHFBIMFO_02649 1.7e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHFBIMFO_02650 8.4e-235 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MHFBIMFO_02651 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MHFBIMFO_02652 3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHFBIMFO_02653 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MHFBIMFO_02654 7.6e-214 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHFBIMFO_02655 6.2e-225 pbuO_1 S permease
MHFBIMFO_02656 1.4e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHFBIMFO_02657 5e-168 S Protein of unknown function (DUF979)
MHFBIMFO_02658 7.6e-118 S Protein of unknown function (DUF969)
MHFBIMFO_02659 8.7e-139 ycsF S Belongs to the UPF0271 (lamB) family
MHFBIMFO_02660 1.3e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MHFBIMFO_02661 2.1e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MHFBIMFO_02662 1.7e-213 EGP Major facilitator Superfamily
MHFBIMFO_02663 2.3e-78 ymaD O redox protein, regulator of disulfide bond formation
MHFBIMFO_02664 5e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MHFBIMFO_02665 5.8e-115 artQ E COG0765 ABC-type amino acid transport system, permease component
MHFBIMFO_02666 7.9e-132 artP ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MHFBIMFO_02667 1.7e-210 hipO3 3.5.1.47 S amidohydrolase
MHFBIMFO_02668 0.0 htpG O Molecular chaperone. Has ATPase activity
MHFBIMFO_02669 6.7e-198 M FFAT motif binding
MHFBIMFO_02670 1.1e-56 I Domain of unknown function (DUF4430)
MHFBIMFO_02671 5.5e-90 S Psort location CytoplasmicMembrane, score
MHFBIMFO_02672 2.6e-117 crtF 2.1.1.210, 2.1.1.281, 2.1.1.79 M Methyltransferase
MHFBIMFO_02673 4.3e-211 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MHFBIMFO_02674 7.6e-40 S Nucleotidyltransferase domain
MHFBIMFO_02675 4.8e-193 adhP 1.1.1.1 C alcohol dehydrogenase
MHFBIMFO_02677 4.1e-83 L Transposase
MHFBIMFO_02678 1.3e-136 L Transposase
MHFBIMFO_02679 1.5e-09 L DDE superfamily endonuclease
MHFBIMFO_02681 1e-53 3.5.1.19 Q Isochorismatase family
MHFBIMFO_02682 5.7e-94 S S4 RNA-binding domain
MHFBIMFO_02683 1.6e-207 L Transposase
MHFBIMFO_02684 0.0 L Domain of unknown function (DUF4277)
MHFBIMFO_02685 7.5e-82 L Transposase
MHFBIMFO_02686 6.5e-190
MHFBIMFO_02687 8.1e-51 yxjI S LURP-one-related
MHFBIMFO_02688 5.7e-266 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHFBIMFO_02689 3.5e-230 L PFAM Transposase, IS116 IS110 IS902
MHFBIMFO_02690 1.7e-268 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHFBIMFO_02691 4e-14 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHFBIMFO_02692 9.3e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHFBIMFO_02693 1e-150 Q N-acetyltransferase
MHFBIMFO_02696 3.9e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHFBIMFO_02697 1.1e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHFBIMFO_02698 4.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHFBIMFO_02699 6.1e-246 aceA 4.1.3.1 C Isocitrate lyase
MHFBIMFO_02700 0.0 aceB 2.3.3.9 C Belongs to the malate synthase family
MHFBIMFO_02701 2.1e-216 camS S COG4851 Protein involved in sex pheromone biosynthesis
MHFBIMFO_02702 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHFBIMFO_02703 4.5e-294 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MHFBIMFO_02704 2e-126 pcrA 3.6.4.12 L AAA domain
MHFBIMFO_02705 2.1e-131 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MHFBIMFO_02706 2.2e-54 yerC S protein conserved in bacteria
MHFBIMFO_02707 2.9e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
MHFBIMFO_02708 0.0 yerA 3.5.4.2 F adenine deaminase
MHFBIMFO_02709 3.2e-36 S Protein of unknown function (DUF2892)
MHFBIMFO_02710 1.1e-236 purD 6.3.4.13 F Belongs to the GARS family
MHFBIMFO_02711 2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MHFBIMFO_02712 1.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHFBIMFO_02713 1.6e-191 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MHFBIMFO_02714 4.2e-272 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHFBIMFO_02715 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHFBIMFO_02716 3.8e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHFBIMFO_02717 9e-40 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHFBIMFO_02718 7.1e-127 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MHFBIMFO_02719 2.3e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHFBIMFO_02720 1.2e-219 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHFBIMFO_02721 3.4e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHFBIMFO_02722 2.9e-31 yebG S NETI protein
MHFBIMFO_02723 3.7e-91 yebE S UPF0316 protein
MHFBIMFO_02724 1.2e-134 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MHFBIMFO_02725 5.3e-43
MHFBIMFO_02726 4.3e-42 S COG NOG14552 non supervised orthologous group
MHFBIMFO_02727 9.3e-223 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHFBIMFO_02728 0.0 2.7.1.201, 2.7.1.211 G phosphotransferase system
MHFBIMFO_02729 1.5e-155 glcT K antiterminator
MHFBIMFO_02730 1.5e-234 pbuG S permease
MHFBIMFO_02732 8e-71 V ABC transporter
MHFBIMFO_02733 5.5e-203 ywjA V ABC transporter
MHFBIMFO_02734 1e-19 ywjA V ABC transporter
MHFBIMFO_02735 9.4e-212 ynfM EGP Major facilitator Superfamily
MHFBIMFO_02736 8.1e-09 S PFAM Uncharacterised protein family UPF0236
MHFBIMFO_02737 3.4e-13 S PFAM Uncharacterised protein family UPF0236
MHFBIMFO_02738 7.6e-256 ybhI P Sodium:sulfate symporter transmembrane region
MHFBIMFO_02739 5.3e-81 L deoxyribonuclease I activity
MHFBIMFO_02740 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
MHFBIMFO_02741 6.6e-212 L Transposase
MHFBIMFO_02742 1.1e-15 S Ribbon-helix-helix protein, copG family
MHFBIMFO_02744 4.2e-101 V ATPase activity
MHFBIMFO_02745 4.1e-261 L Transposase DDE domain group 1
MHFBIMFO_02746 1.6e-07 yhcG V ABC transporter, ATP-binding protein
MHFBIMFO_02747 1.4e-57 yhcF K Transcriptional regulator
MHFBIMFO_02748 9.6e-43 padR K negative regulation of transcription, DNA-templated
MHFBIMFO_02749 8.1e-114 ywnB S NAD(P)H-binding
MHFBIMFO_02750 4.4e-86 folT 2.7.13.3 T ECF transporter, substrate-specific component
MHFBIMFO_02751 1.5e-35 yeeD O Belongs to the sulfur carrier protein TusA family
MHFBIMFO_02752 2.9e-193 yeeE S Sulphur transport
MHFBIMFO_02753 2.3e-212 L Transposase
MHFBIMFO_02754 2.5e-15 S Ribbon-helix-helix protein, copG family
MHFBIMFO_02755 4.9e-173 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHFBIMFO_02756 1.5e-08
MHFBIMFO_02757 2.9e-30 ybxH S Family of unknown function (DUF5370)
MHFBIMFO_02758 6.3e-60 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MHFBIMFO_02759 5.4e-65 L PFAM transposase IS4 family protein
MHFBIMFO_02760 3.2e-172 L PFAM transposase IS4 family protein
MHFBIMFO_02761 8.3e-93 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MHFBIMFO_02762 3.7e-128 fecE 3.6.3.34 HP ABC transporter
MHFBIMFO_02763 3.1e-93
MHFBIMFO_02765 5.4e-75 P nitrite transmembrane transporter activity
MHFBIMFO_02766 1.3e-271 L Transposase, IS4 family protein
MHFBIMFO_02767 8.8e-63 EGP Major facilitator Superfamily
MHFBIMFO_02768 1.4e-27 K Helix-turn-helix domain
MHFBIMFO_02769 4.7e-31
MHFBIMFO_02770 2.7e-31 S Domain of unknown function (DUF4177)
MHFBIMFO_02771 8.4e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MHFBIMFO_02773 8e-154 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHFBIMFO_02774 3.8e-284 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHFBIMFO_02775 7.1e-106 pncA Q COG1335 Amidases related to nicotinamidase
MHFBIMFO_02776 2.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MHFBIMFO_02777 0.0 ykoS
MHFBIMFO_02778 6.6e-187 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MHFBIMFO_02779 4.1e-68 yngA S GtrA-like protein
MHFBIMFO_02780 9.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHFBIMFO_02781 5.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHFBIMFO_02782 3.4e-124 ydiL S CAAX protease self-immunity
MHFBIMFO_02783 4.7e-28 S Domain of unknown function (DUF4305)
MHFBIMFO_02784 1.3e-131 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHFBIMFO_02785 4.6e-123 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHFBIMFO_02786 1.1e-09 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHFBIMFO_02787 0.0 ydiF S ABC transporter
MHFBIMFO_02788 8.1e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHFBIMFO_02789 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHFBIMFO_02790 4.4e-129 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MHFBIMFO_02791 4e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MHFBIMFO_02793 5.3e-43
MHFBIMFO_02794 4.3e-42 S COG NOG14552 non supervised orthologous group
MHFBIMFO_02803 2.7e-93 ydcK S Belongs to the SprT family
MHFBIMFO_02804 0.0 yhgF K COG2183 Transcriptional accessory protein
MHFBIMFO_02805 5.2e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MHFBIMFO_02806 7.5e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHFBIMFO_02807 3e-81 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MHFBIMFO_02808 5.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
MHFBIMFO_02809 1.8e-195 rsbU 3.1.3.3 KT phosphatase
MHFBIMFO_02810 2e-70 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MHFBIMFO_02811 8.1e-55 rsbS T antagonist
MHFBIMFO_02812 8.8e-153 rsbR T Positive regulator of sigma-B
MHFBIMFO_02813 7.2e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MHFBIMFO_02814 2e-40 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MHFBIMFO_02815 7.5e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHFBIMFO_02816 1.1e-189 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MHFBIMFO_02817 7.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHFBIMFO_02818 1.1e-104 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MHFBIMFO_02819 1.7e-260 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHFBIMFO_02820 1.3e-48 L COG2826 Transposase and inactivated derivatives, IS30 family
MHFBIMFO_02821 1.1e-107 E Lysine exporter protein LysE YggA
MHFBIMFO_02822 2.7e-123 otsB2 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MHFBIMFO_02823 7.7e-177 yvdE K Transcriptional regulator
MHFBIMFO_02824 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MHFBIMFO_02825 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MHFBIMFO_02826 1.8e-226 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MHFBIMFO_02827 5e-243 malC P COG1175 ABC-type sugar transport systems, permease components
MHFBIMFO_02828 1e-156 malD P transport
MHFBIMFO_02829 3.9e-148 malA S Protein of unknown function (DUF1189)
MHFBIMFO_02830 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MHFBIMFO_02831 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MHFBIMFO_02832 7.3e-261 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHFBIMFO_02833 1.5e-197 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MHFBIMFO_02834 4.2e-149
MHFBIMFO_02835 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MHFBIMFO_02836 2.3e-73 cueR K transcriptional
MHFBIMFO_02837 1.7e-249 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MHFBIMFO_02839 4.1e-308 ywqB S Zinc finger, swim domain protein
MHFBIMFO_02840 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHFBIMFO_02842 1.9e-71 ywpF S YwpF-like protein
MHFBIMFO_02843 3.3e-64 ssbB L Single-stranded DNA-binding protein
MHFBIMFO_02845 3.5e-73 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHFBIMFO_02846 2.7e-149 flhP N flagellar basal body
MHFBIMFO_02847 3.8e-145 flhO N flagellar basal body
MHFBIMFO_02848 7.8e-180 mbl D Rod shape-determining protein
MHFBIMFO_02849 1.1e-40 spoIIID K Stage III sporulation protein D
MHFBIMFO_02850 1.8e-128 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MHFBIMFO_02851 2.8e-185 spoIID D Stage II sporulation protein D
MHFBIMFO_02852 1.2e-08 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHFBIMFO_02853 1.3e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHFBIMFO_02854 3.9e-136 ywmB S TATA-box binding
MHFBIMFO_02855 1.8e-34 ywzB S membrane
MHFBIMFO_02856 2.1e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MHFBIMFO_02857 2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHFBIMFO_02858 1.4e-148 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHFBIMFO_02859 5.9e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHFBIMFO_02860 1.3e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHFBIMFO_02861 1.3e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHFBIMFO_02862 2e-24 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHFBIMFO_02863 5.8e-121 atpB C it plays a direct role in the translocation of protons across the membrane
MHFBIMFO_02864 8e-53 atpI S ATP synthase I chain
MHFBIMFO_02865 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHFBIMFO_02866 5.4e-239 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHFBIMFO_02867 4.4e-95 ywlG S Belongs to the UPF0340 family
MHFBIMFO_02868 3.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MHFBIMFO_02869 2e-175 mcpA NT Chemotaxis
MHFBIMFO_02870 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHFBIMFO_02871 1.6e-86 mntP P Probably functions as a manganese efflux pump
MHFBIMFO_02872 3.1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHFBIMFO_02873 6.9e-136 spoIIR S Stage II sporulation protein R (spore_II_R)
MHFBIMFO_02874 1.7e-162 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHFBIMFO_02875 1.7e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHFBIMFO_02877 1.3e-110 tdk 2.7.1.21 F thymidine kinase
MHFBIMFO_02878 2.2e-33 rpmE J Ribosomal protein L31
MHFBIMFO_02879 2.7e-230 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHFBIMFO_02880 2.7e-174 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MHFBIMFO_02881 8.1e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHFBIMFO_02882 2.6e-115 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHFBIMFO_02883 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MHFBIMFO_02884 6e-61 spo0F T response regulator
MHFBIMFO_02885 1.1e-217
MHFBIMFO_02886 2.4e-150
MHFBIMFO_02887 2.2e-125 yhcG V ABC transporter, ATP-binding protein
MHFBIMFO_02888 1.2e-67 K helix_turn_helix gluconate operon transcriptional repressor
MHFBIMFO_02889 2.4e-308 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHFBIMFO_02890 3.5e-50 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHFBIMFO_02892 0.0 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
MHFBIMFO_02893 1.3e-111 kstR2_2 K Transcriptional regulator
MHFBIMFO_02894 3.8e-215 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MHFBIMFO_02895 3.7e-210 mmgC I acyl-CoA dehydrogenase
MHFBIMFO_02896 2.6e-219 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
MHFBIMFO_02897 0.0 fadF C COG0247 Fe-S oxidoreductase
MHFBIMFO_02898 4e-215 cls I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MHFBIMFO_02899 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MHFBIMFO_02900 5e-75 ywiB S Domain of unknown function (DUF1934)
MHFBIMFO_02901 2.9e-170 speB 3.5.3.11 E Belongs to the arginase family
MHFBIMFO_02902 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHFBIMFO_02903 1.7e-93 ywhD S YwhD family
MHFBIMFO_02904 7.8e-120 ywhC S Peptidase M50
MHFBIMFO_02905 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MHFBIMFO_02906 1.5e-89 ywgA 2.1.1.72, 3.1.21.3
MHFBIMFO_02907 1.2e-257 ywfO S COG1078 HD superfamily phosphohydrolases
MHFBIMFO_02908 5.7e-100 rsfA S Transcriptional regulator
MHFBIMFO_02909 6.1e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MHFBIMFO_02910 6e-177 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MHFBIMFO_02911 1.9e-186 S PFAM Uncharacterised protein family UPF0236
MHFBIMFO_02912 1.2e-120 S PFAM Uncharacterised protein family UPF0236
MHFBIMFO_02913 9.5e-146 ywfI C May function as heme-dependent peroxidase
MHFBIMFO_02914 2.5e-15 S Ribbon-helix-helix protein, copG family
MHFBIMFO_02915 4.2e-214 L Transposase
MHFBIMFO_02916 5.7e-74 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MHFBIMFO_02917 7e-54 ywdK S small membrane protein
MHFBIMFO_02918 1.7e-38 S Family of unknown function (DUF5327)
MHFBIMFO_02920 5.2e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHFBIMFO_02921 2.5e-56 S Heat induced stress protein YflT
MHFBIMFO_02923 3.5e-19 S Circ_ocin_uber circular bacteriocin, circularin A uberolysin family protein
MHFBIMFO_02924 1.2e-291
MHFBIMFO_02925 2.7e-43 S Stage II sporulation protein M
MHFBIMFO_02926 3.3e-121 V ATPases associated with a variety of cellular activities
MHFBIMFO_02929 7e-265 L Transposase, IS4 family protein
MHFBIMFO_02930 5.6e-152 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHFBIMFO_02931 3.9e-62 yojF S Protein of unknown function (DUF1806)
MHFBIMFO_02932 1.5e-129 bshB2 S deacetylase
MHFBIMFO_02933 8.9e-164 ycsE S hydrolases of the HAD superfamily
MHFBIMFO_02934 0.0 recQ 3.6.4.12 L DNA helicase
MHFBIMFO_02935 4.5e-233 phoA 3.1.3.1 P Belongs to the alkaline phosphatase family
MHFBIMFO_02936 1.6e-154 ybbH_2 K Transcriptional regulator
MHFBIMFO_02937 1.3e-159 S Alpha/beta hydrolase of unknown function (DUF915)
MHFBIMFO_02938 7.7e-14
MHFBIMFO_02939 5.5e-231 T His Kinase A (phosphoacceptor) domain
MHFBIMFO_02940 4.4e-126 T Two component transcriptional regulator, winged helix family
MHFBIMFO_02941 1.4e-77
MHFBIMFO_02942 7.3e-115 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHFBIMFO_02944 1.3e-117 ywbG M effector of murein hydrolase
MHFBIMFO_02945 2.9e-58 ywbH S LrgA family
MHFBIMFO_02946 3.3e-180 ywbI K Transcriptional regulator
MHFBIMFO_02947 0.0 asnO 6.3.5.4 E Asparagine synthase
MHFBIMFO_02948 3.7e-129 S Protein of unknown function (DUF1646)
MHFBIMFO_02949 3.5e-71 S Threonine/Serine exporter, ThrE
MHFBIMFO_02950 2.5e-130 thrE S Putative threonine/serine exporter
MHFBIMFO_02951 7.3e-208 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MHFBIMFO_02952 0.0 cstA T Carbon starvation protein
MHFBIMFO_02953 2.1e-154 metQ M Belongs to the nlpA lipoprotein family
MHFBIMFO_02954 2.9e-98 metI P COG2011 ABC-type metal ion transport system, permease component
MHFBIMFO_02955 3.2e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHFBIMFO_02956 8.3e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MHFBIMFO_02957 2.4e-101
MHFBIMFO_02958 4.4e-222 pilM NU Pilus assembly protein
MHFBIMFO_02959 8.2e-241 yisQ V Mate efflux family protein
MHFBIMFO_02960 4.5e-154 M Glycosyl transferase family 8
MHFBIMFO_02961 1.8e-231 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MHFBIMFO_02962 1.2e-272 EGP Major facilitator Superfamily
MHFBIMFO_02963 5.9e-51 S Leucine-rich repeat (LRR) protein
MHFBIMFO_02964 6.8e-15 S Leucine-rich repeat (LRR) protein
MHFBIMFO_02965 3.2e-226 uraA F Xanthine uracil
MHFBIMFO_02966 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MHFBIMFO_02967 1.2e-126 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHFBIMFO_02968 2.7e-131 L Transposase
MHFBIMFO_02969 3.8e-136
MHFBIMFO_02970 1.4e-206 ugpC 3.6.3.20 P Belongs to the ABC transporter superfamily
MHFBIMFO_02971 2.2e-168 ugpA G ABC transporter (permease)
MHFBIMFO_02972 1.9e-147 ugpE P Glycerol-3-phosphate ABC transporter permease
MHFBIMFO_02974 9.6e-250 ugpB G Glycerol-3-phosphate ABC transporter substrate-binding protein
MHFBIMFO_02975 1.4e-147 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MHFBIMFO_02976 1.3e-60 S Domain of unknown function (DUF2935)
MHFBIMFO_02977 2.9e-32 tnp4 L Transposase, Mutator family
MHFBIMFO_02978 7.4e-248 L Transposase, IS4 family protein
MHFBIMFO_02979 1.4e-289 L Transposase
MHFBIMFO_02981 3.8e-259 L PFAM Transposase, IS4-like
MHFBIMFO_02982 9.1e-301 msbA2 3.6.3.44 V ABC transporter
MHFBIMFO_02983 5.4e-113 yhhQ_2 S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MHFBIMFO_02984 7.5e-99 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MHFBIMFO_02985 0.0 S MMPL domain protein
MHFBIMFO_02986 2.9e-300 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MHFBIMFO_02987 7.5e-45 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MHFBIMFO_02988 6.3e-148 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHFBIMFO_02989 8.9e-239 LYS1 1.5.1.7 E Saccharopine dehydrogenase
MHFBIMFO_02990 4.8e-226 nspC 4.1.1.96 E Pyridoxal-dependent decarboxylase, C-terminal sheet domain
MHFBIMFO_02991 1.7e-32 S PD-(D/E)XK nuclease family transposase
MHFBIMFO_02992 5.6e-208 S Domain of unknown function (DUF1611_N) Rossmann-like domain
MHFBIMFO_02993 3e-215 5.1.1.12 E Alanine racemase, N-terminal domain
MHFBIMFO_02994 4e-137 cjaA ET Belongs to the bacterial solute-binding protein 3 family
MHFBIMFO_02995 4.2e-130 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
MHFBIMFO_02996 1.4e-103 E amino acid ABC transporter
MHFBIMFO_02997 3.4e-115 papP E amino acid ABC transporter
MHFBIMFO_02998 1.4e-294 mqo 1.1.5.4 S malate quinone oxidoreductase
MHFBIMFO_02999 1.2e-269 kgtP EGP -transporter
MHFBIMFO_03000 0.0 3.6.4.12, 3.6.4.13 L HELICc2
MHFBIMFO_03002 1.9e-80 L Transposase IS4 family protein
MHFBIMFO_03003 6.9e-141 L Transposase IS4 family protein
MHFBIMFO_03004 3.3e-12 mcrB L Restriction endonuclease
MHFBIMFO_03005 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MHFBIMFO_03006 2.5e-255 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MHFBIMFO_03007 8.5e-303 hsdM 2.1.1.72 V Type I restriction-modification system
MHFBIMFO_03008 3e-87
MHFBIMFO_03009 9.5e-167 tnp L transposase activity
MHFBIMFO_03010 5e-76 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHFBIMFO_03011 4.3e-228 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHFBIMFO_03012 1.1e-147 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MHFBIMFO_03013 3.9e-142 yycI S protein conserved in bacteria
MHFBIMFO_03014 4.3e-247 yycH S protein conserved in bacteria
MHFBIMFO_03015 0.0 vicK 2.7.13.3 T Histidine kinase
MHFBIMFO_03016 1.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHFBIMFO_03019 1.9e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHFBIMFO_03020 2.2e-249 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MHFBIMFO_03021 5.3e-72 rplI J binds to the 23S rRNA
MHFBIMFO_03022 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MHFBIMFO_03023 3.5e-158 yybS S membrane
MHFBIMFO_03024 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHFBIMFO_03025 2.2e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHFBIMFO_03026 5e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
MHFBIMFO_03027 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MHFBIMFO_03028 2.1e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MHFBIMFO_03029 1.6e-117 ribE 2.5.1.9 H Riboflavin synthase
MHFBIMFO_03030 2.8e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MHFBIMFO_03031 1e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHFBIMFO_03032 1.1e-32 yyzM S protein conserved in bacteria
MHFBIMFO_03033 7.2e-156 ykuT M Mechanosensitive ion channel
MHFBIMFO_03034 1.3e-113 yyaC S Sporulation protein YyaC
MHFBIMFO_03035 3.2e-119 ydfK S Protein of unknown function (DUF554)
MHFBIMFO_03036 2.2e-151 spo0J K Belongs to the ParB family
MHFBIMFO_03037 6.9e-136 soj D COG1192 ATPases involved in chromosome partitioning
MHFBIMFO_03038 9.1e-153 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MHFBIMFO_03039 7.9e-134 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MHFBIMFO_03040 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHFBIMFO_03041 1.2e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHFBIMFO_03042 1.4e-110 jag S single-stranded nucleic acid binding R3H
MHFBIMFO_03043 3.2e-128 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHFBIMFO_03044 4.2e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)