ORF_ID e_value Gene_name EC_number CAZy COGs Description
LCLEADBE_00001 3.3e-280 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LCLEADBE_00002 1.9e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LCLEADBE_00003 9.9e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LCLEADBE_00004 3.8e-84 S Protein of unknown function (DUF721)
LCLEADBE_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCLEADBE_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCLEADBE_00007 8.4e-51 S Transmembrane domain of unknown function (DUF3566)
LCLEADBE_00008 2.7e-188 lacR K Transcriptional regulator, LacI family
LCLEADBE_00009 2.4e-15 lacS G Psort location CytoplasmicMembrane, score 10.00
LCLEADBE_00010 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
LCLEADBE_00011 1.1e-206 V VanZ like family
LCLEADBE_00013 3.9e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
LCLEADBE_00014 6.3e-198 S Psort location CytoplasmicMembrane, score
LCLEADBE_00017 1.5e-123 S Protein of unknown function DUF45
LCLEADBE_00019 3.6e-257 S Domain of unknown function (DUF4143)
LCLEADBE_00020 3.3e-83 dps P Belongs to the Dps family
LCLEADBE_00021 7.2e-117 L Transposase and inactivated derivatives IS30 family
LCLEADBE_00022 1.1e-88 amyE G Bacterial extracellular solute-binding protein
LCLEADBE_00023 1e-114 S Protein of unknown function, DUF624
LCLEADBE_00024 3.8e-201 K Periplasmic binding protein domain
LCLEADBE_00025 2.1e-292 3.2.1.26 GH32 G Glycosyl hydrolases family 32
LCLEADBE_00026 5.9e-252 amyE G Bacterial extracellular solute-binding protein
LCLEADBE_00027 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
LCLEADBE_00028 3e-187 K Psort location Cytoplasmic, score
LCLEADBE_00029 4.5e-213 L Transposase and inactivated derivatives IS30 family
LCLEADBE_00030 1e-147 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
LCLEADBE_00031 4.1e-52 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
LCLEADBE_00032 7e-75 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
LCLEADBE_00033 5.8e-152 rafG G ABC transporter permease
LCLEADBE_00034 4.2e-150 malC G Binding-protein-dependent transport system inner membrane component
LCLEADBE_00035 1.5e-30 K Psort location Cytoplasmic, score
LCLEADBE_00036 6.9e-72 K Psort location Cytoplasmic, score
LCLEADBE_00037 2e-76 amyE G Bacterial extracellular solute-binding protein
LCLEADBE_00038 4.8e-116 amyE G Bacterial extracellular solute-binding protein
LCLEADBE_00040 5.9e-229 M Protein of unknown function (DUF2961)
LCLEADBE_00041 3.2e-185 amyE G Bacterial extracellular solute-binding protein
LCLEADBE_00042 8.9e-187 K Periplasmic binding protein-like domain
LCLEADBE_00043 5.2e-267 amyE G Bacterial extracellular solute-binding protein
LCLEADBE_00044 5.6e-83 dps P Belongs to the Dps family
LCLEADBE_00045 2.7e-236 ytfL P Transporter associated domain
LCLEADBE_00046 9.7e-211 S AAA ATPase domain
LCLEADBE_00047 6.6e-122 cah 4.2.1.1 P Reversible hydration of carbon dioxide
LCLEADBE_00048 1e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
LCLEADBE_00049 0.0 trxB2 1.8.1.9 C Thioredoxin domain
LCLEADBE_00050 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
LCLEADBE_00051 3.8e-165
LCLEADBE_00052 8.8e-102 S Uncharacterised protein conserved in bacteria (DUF2194)
LCLEADBE_00053 8.4e-210 S Uncharacterised protein conserved in bacteria (DUF2194)
LCLEADBE_00054 3.5e-282 pelF GT4 M Domain of unknown function (DUF3492)
LCLEADBE_00055 2.3e-287 pelG S Putative exopolysaccharide Exporter (EPS-E)
LCLEADBE_00056 0.0 cotH M CotH kinase protein
LCLEADBE_00057 4.1e-158 P VTC domain
LCLEADBE_00058 8.5e-111 S Domain of unknown function (DUF4956)
LCLEADBE_00059 0.0 yliE T Putative diguanylate phosphodiesterase
LCLEADBE_00060 9.7e-129 S AAA domain
LCLEADBE_00061 0.0 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LCLEADBE_00063 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LCLEADBE_00064 0.0 yjjP S Threonine/Serine exporter, ThrE
LCLEADBE_00065 1.1e-300 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LCLEADBE_00066 3.4e-167 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
LCLEADBE_00067 0.0 S Amidohydrolase family
LCLEADBE_00068 3.2e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
LCLEADBE_00069 8.5e-42 S Protein of unknown function (DUF3073)
LCLEADBE_00070 4.4e-103 I Sterol carrier protein
LCLEADBE_00071 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LCLEADBE_00072 1.2e-35
LCLEADBE_00073 8.5e-123 gluP 3.4.21.105 S Rhomboid family
LCLEADBE_00074 2.6e-69 crgA D Involved in cell division
LCLEADBE_00075 1.8e-118 S Bacterial protein of unknown function (DUF881)
LCLEADBE_00076 2.1e-232 srtA 3.4.22.70 M Sortase family
LCLEADBE_00077 2e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
LCLEADBE_00078 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
LCLEADBE_00079 1e-173 T Protein tyrosine kinase
LCLEADBE_00080 3.4e-264 pbpA M penicillin-binding protein
LCLEADBE_00081 6.9e-279 rodA D Belongs to the SEDS family
LCLEADBE_00082 3.7e-272 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
LCLEADBE_00083 1.6e-75 fhaB T Inner membrane component of T3SS, cytoplasmic domain
LCLEADBE_00084 2e-129 fhaA T Protein of unknown function (DUF2662)
LCLEADBE_00085 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
LCLEADBE_00086 6.8e-214 pldB 3.1.1.5 I Serine aminopeptidase, S33
LCLEADBE_00087 2.4e-92 hsp20 O Hsp20/alpha crystallin family
LCLEADBE_00088 3.2e-178 yddG EG EamA-like transporter family
LCLEADBE_00089 1.3e-23
LCLEADBE_00090 1.9e-256 S Putative esterase
LCLEADBE_00091 0.0 lysX S Uncharacterised conserved protein (DUF2156)
LCLEADBE_00092 4.8e-201 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LCLEADBE_00093 8.9e-133 S Pyridoxamine 5'-phosphate oxidase
LCLEADBE_00094 2.6e-202 S Fic/DOC family
LCLEADBE_00095 1.4e-163 M Glycosyltransferase like family 2
LCLEADBE_00096 0.0 KL Domain of unknown function (DUF3427)
LCLEADBE_00097 1.1e-74 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
LCLEADBE_00098 1.2e-52 ybjQ S Putative heavy-metal-binding
LCLEADBE_00099 7.5e-147 yplQ S Haemolysin-III related
LCLEADBE_00101 3.3e-263 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LCLEADBE_00102 1.1e-281 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
LCLEADBE_00103 0.0 cadA P E1-E2 ATPase
LCLEADBE_00104 4.8e-279 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
LCLEADBE_00105 1.5e-172 htpX O Belongs to the peptidase M48B family
LCLEADBE_00107 6e-174 yicL EG EamA-like transporter family
LCLEADBE_00108 3.3e-200 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
LCLEADBE_00109 1e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LCLEADBE_00110 2.2e-282 clcA P Voltage gated chloride channel
LCLEADBE_00111 2.6e-149 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCLEADBE_00112 1.9e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCLEADBE_00113 2.2e-204 K helix_turn _helix lactose operon repressor
LCLEADBE_00114 1.6e-301 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
LCLEADBE_00115 5.4e-279 scrT G Transporter major facilitator family protein
LCLEADBE_00116 2.8e-180 K helix_turn _helix lactose operon repressor
LCLEADBE_00117 3.8e-254 yhjE EGP Sugar (and other) transporter
LCLEADBE_00118 2.4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LCLEADBE_00119 1.3e-187 K Periplasmic binding protein domain
LCLEADBE_00120 5.9e-252 G Bacterial extracellular solute-binding protein
LCLEADBE_00121 6.9e-209 malC P Binding-protein-dependent transport system inner membrane component
LCLEADBE_00122 3.4e-169 P Binding-protein-dependent transport system inner membrane component
LCLEADBE_00123 4.3e-285 bglA 3.2.1.21 G Glycosyl hydrolase family 1
LCLEADBE_00124 3.7e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LCLEADBE_00125 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
LCLEADBE_00126 1.4e-187 K Psort location Cytoplasmic, score
LCLEADBE_00127 0.0 M cell wall anchor domain protein
LCLEADBE_00128 0.0 M domain protein
LCLEADBE_00129 8.6e-176 3.4.22.70 M Sortase family
LCLEADBE_00130 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
LCLEADBE_00131 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
LCLEADBE_00132 1.2e-235 malE G Bacterial extracellular solute-binding protein
LCLEADBE_00133 9.4e-256 malF G Binding-protein-dependent transport system inner membrane component
LCLEADBE_00134 1.2e-166 malG G Binding-protein-dependent transport system inner membrane component
LCLEADBE_00135 4.5e-146 traX S TraX protein
LCLEADBE_00136 1.1e-194 K Psort location Cytoplasmic, score
LCLEADBE_00137 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
LCLEADBE_00138 0.0 dnaK O Heat shock 70 kDa protein
LCLEADBE_00139 1e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LCLEADBE_00140 9.4e-157 dnaJ1 O DnaJ molecular chaperone homology domain
LCLEADBE_00141 1.2e-103 hspR K transcriptional regulator, MerR family
LCLEADBE_00142 3.1e-17 F Psort location CytoplasmicMembrane, score 10.00
LCLEADBE_00143 1.5e-114 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
LCLEADBE_00144 1.1e-141 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
LCLEADBE_00145 2.3e-127 S HAD hydrolase, family IA, variant 3
LCLEADBE_00146 1.6e-134 dedA S SNARE associated Golgi protein
LCLEADBE_00147 5.8e-125 cpaE D bacterial-type flagellum organization
LCLEADBE_00148 9.1e-192 cpaF U Type II IV secretion system protein
LCLEADBE_00149 1.2e-74 U Type ii secretion system
LCLEADBE_00150 3.1e-116 gspF NU Type II secretion system (T2SS), protein F
LCLEADBE_00151 1.1e-41 S Protein of unknown function (DUF4244)
LCLEADBE_00152 3.7e-58 U TadE-like protein
LCLEADBE_00153 6.5e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
LCLEADBE_00154 1.2e-216 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
LCLEADBE_00155 6.5e-97 K Bacterial regulatory proteins, tetR family
LCLEADBE_00156 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
LCLEADBE_00157 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LCLEADBE_00158 8.9e-202 3.4.22.70 M Sortase family
LCLEADBE_00159 4.8e-69 V Abi-like protein
LCLEADBE_00160 3.6e-193 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LCLEADBE_00161 1.3e-134 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
LCLEADBE_00162 9.4e-98 askB 1.1.1.3, 2.7.2.4 E ACT domain
LCLEADBE_00163 9e-214 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LCLEADBE_00164 9.6e-112
LCLEADBE_00165 1.9e-61 L Transposase and inactivated derivatives IS30 family
LCLEADBE_00166 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_00167 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_00168 1.2e-28 L Transposase and inactivated derivatives IS30 family
LCLEADBE_00169 1.3e-199 P Bacterial extracellular solute-binding protein
LCLEADBE_00170 2.4e-151 U Binding-protein-dependent transport system inner membrane component
LCLEADBE_00171 5.8e-161 U Binding-protein-dependent transport system inner membrane component
LCLEADBE_00172 5.6e-203 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LCLEADBE_00173 1.3e-159 I type I phosphodiesterase nucleotide pyrophosphatase
LCLEADBE_00175 1.2e-08 L IstB-like ATP binding protein
LCLEADBE_00176 4.7e-56 L IstB-like ATP binding protein
LCLEADBE_00177 3.9e-289 L PFAM Integrase catalytic
LCLEADBE_00178 4e-175 L Domain of unknown function (DUF4862)
LCLEADBE_00179 3e-171 2.7.1.2 GK ROK family
LCLEADBE_00180 1.3e-125 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LCLEADBE_00181 3e-161 3.5.1.106 I carboxylic ester hydrolase activity
LCLEADBE_00182 2.7e-304 E Bacterial extracellular solute-binding proteins, family 5 Middle
LCLEADBE_00183 4.6e-153 oppB6 EP Binding-protein-dependent transport system inner membrane component
LCLEADBE_00184 0.0 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
LCLEADBE_00185 1.7e-148 oppF E ATPases associated with a variety of cellular activities
LCLEADBE_00186 2e-180 nanL 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
LCLEADBE_00187 3.7e-148 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LCLEADBE_00188 9.1e-14 nagA 3.5.1.25 G Amidohydrolase family
LCLEADBE_00189 0.0 nanI 3.2.1.18 GH33 G BNR repeat-like domain
LCLEADBE_00190 2.6e-244 P Domain of unknown function (DUF4143)
LCLEADBE_00191 9e-153 K FCD
LCLEADBE_00192 3.2e-275 S Calcineurin-like phosphoesterase
LCLEADBE_00193 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LCLEADBE_00194 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
LCLEADBE_00195 1.3e-170 3.6.1.27 I PAP2 superfamily
LCLEADBE_00196 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCLEADBE_00197 2.6e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LCLEADBE_00198 7.8e-208 holB 2.7.7.7 L DNA polymerase III
LCLEADBE_00199 8e-106 K helix_turn _helix lactose operon repressor
LCLEADBE_00200 3.3e-37 ptsH G PTS HPr component phosphorylation site
LCLEADBE_00202 4.9e-296 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LCLEADBE_00203 4.6e-30 3.4.17.14 M domain, Protein
LCLEADBE_00204 2.3e-19 D nuclear chromosome segregation
LCLEADBE_00205 2.7e-108 S Phosphatidylethanolamine-binding protein
LCLEADBE_00206 0.0 pepD E Peptidase family C69
LCLEADBE_00207 4.8e-290 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
LCLEADBE_00208 1e-62 S Macrophage migration inhibitory factor (MIF)
LCLEADBE_00209 8.4e-96 S GtrA-like protein
LCLEADBE_00210 9.7e-248 EGP Major facilitator Superfamily
LCLEADBE_00211 8.1e-125 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
LCLEADBE_00212 2.2e-118
LCLEADBE_00213 5e-234 3.1.1.31 G Lactonase, 7-bladed beta-propeller
LCLEADBE_00214 1.7e-161 S Protein of unknown function (DUF805)
LCLEADBE_00216 2.9e-295 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LCLEADBE_00219 4.7e-69
LCLEADBE_00220 2.2e-135 yoaK S Protein of unknown function (DUF1275)
LCLEADBE_00221 5.7e-56 ydeP K HxlR-like helix-turn-helix
LCLEADBE_00222 1.2e-79 XK27_10430 S NAD(P)H-binding
LCLEADBE_00223 6.2e-307 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LCLEADBE_00224 1.5e-55
LCLEADBE_00225 4.5e-267 EGP Major Facilitator Superfamily
LCLEADBE_00226 0.0 1.3.3.6, 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
LCLEADBE_00227 0.0 H Beta-ketoacyl synthase, C-terminal domain
LCLEADBE_00228 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_00229 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_00230 5e-116 K WHG domain
LCLEADBE_00231 7e-113 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
LCLEADBE_00232 2.6e-91
LCLEADBE_00233 5.4e-152 L HNH endonuclease
LCLEADBE_00235 2.1e-46 L Transposase
LCLEADBE_00236 3.8e-132 tnp7109-21 L Integrase core domain
LCLEADBE_00237 4.5e-174 S Domain of unknown function (DUF4928)
LCLEADBE_00238 6.7e-231 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
LCLEADBE_00239 4.2e-283 S FRG domain
LCLEADBE_00240 0.0 T AAA domain
LCLEADBE_00241 8.7e-27
LCLEADBE_00242 4.1e-282 L Phage integrase, N-terminal SAM-like domain
LCLEADBE_00244 0.0 efeU_1 P Iron permease FTR1 family
LCLEADBE_00245 1.6e-99 tpd P Fe2+ transport protein
LCLEADBE_00246 7.7e-233 S Predicted membrane protein (DUF2318)
LCLEADBE_00247 1.7e-227 macB_2 V ABC transporter permease
LCLEADBE_00248 7.7e-202 Z012_06715 V FtsX-like permease family
LCLEADBE_00249 1.2e-146 macB V ABC transporter, ATP-binding protein
LCLEADBE_00250 1.7e-67 S FMN_bind
LCLEADBE_00251 3.2e-101 K Psort location Cytoplasmic, score 8.87
LCLEADBE_00252 2.1e-307 pip S YhgE Pip domain protein
LCLEADBE_00253 0.0 pip S YhgE Pip domain protein
LCLEADBE_00254 2.5e-253 S Putative ABC-transporter type IV
LCLEADBE_00255 1.5e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LCLEADBE_00256 1.3e-140 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
LCLEADBE_00257 3.7e-193 opcA G Glucose-6-phosphate dehydrogenase subunit
LCLEADBE_00258 2e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LCLEADBE_00259 1e-294 3.5.2.6 V Beta-lactamase enzyme family
LCLEADBE_00261 2.2e-303 pepD E Peptidase family C69
LCLEADBE_00262 1e-198 XK27_01805 M Glycosyltransferase like family 2
LCLEADBE_00263 1e-151 icaR K Bacterial regulatory proteins, tetR family
LCLEADBE_00264 9.9e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LCLEADBE_00265 6.9e-229 amt U Ammonium Transporter Family
LCLEADBE_00266 1e-54 glnB K Nitrogen regulatory protein P-II
LCLEADBE_00267 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
LCLEADBE_00268 1.3e-241 dinF V MatE
LCLEADBE_00269 3.3e-257 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LCLEADBE_00270 6.6e-265 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
LCLEADBE_00271 1.3e-142 cobQ S CobB/CobQ-like glutamine amidotransferase domain
LCLEADBE_00272 5.5e-38 S granule-associated protein
LCLEADBE_00273 0.0 ubiB S ABC1 family
LCLEADBE_00274 3.5e-71 K Periplasmic binding protein domain
LCLEADBE_00275 2.4e-171 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
LCLEADBE_00276 2e-80 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
LCLEADBE_00277 9.1e-31 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
LCLEADBE_00278 1.4e-156 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LCLEADBE_00279 1.2e-109 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCLEADBE_00280 3.5e-62 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCLEADBE_00281 4.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
LCLEADBE_00282 4e-76 ssb1 L Single-stranded DNA-binding protein
LCLEADBE_00283 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LCLEADBE_00284 1.6e-71 rplI J Binds to the 23S rRNA
LCLEADBE_00286 1.7e-117
LCLEADBE_00287 3.1e-130 V ABC transporter
LCLEADBE_00288 1.3e-111 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LCLEADBE_00289 6.5e-210 2.7.13.3 T Histidine kinase
LCLEADBE_00290 1.8e-20 L Transposase
LCLEADBE_00291 3.2e-204 EGP Major Facilitator Superfamily
LCLEADBE_00292 6.2e-43
LCLEADBE_00293 8.6e-60
LCLEADBE_00294 1e-127 xerH L Belongs to the 'phage' integrase family
LCLEADBE_00295 1.9e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
LCLEADBE_00296 0.0 pacS 1.9.3.1, 3.6.3.54 P E1-E2 ATPase
LCLEADBE_00297 3.3e-43 csoR S Metal-sensitive transcriptional repressor
LCLEADBE_00298 1.6e-210 rmuC S RmuC family
LCLEADBE_00299 3.7e-111 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LCLEADBE_00300 2.1e-171 spoU 2.1.1.185 J RNA methyltransferase TrmH family
LCLEADBE_00301 6.4e-168 V ABC transporter
LCLEADBE_00302 5.7e-181
LCLEADBE_00303 3e-56 K Psort location Cytoplasmic, score
LCLEADBE_00304 4.2e-38 K Psort location Cytoplasmic, score
LCLEADBE_00305 4.1e-51 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCLEADBE_00306 3.7e-290 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LCLEADBE_00307 2.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCLEADBE_00308 1.1e-195 2.3.1.57 J Acetyltransferase (GNAT) domain
LCLEADBE_00309 2.5e-52 S Protein of unknown function (DUF2469)
LCLEADBE_00310 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
LCLEADBE_00311 6.8e-297 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LCLEADBE_00312 9.6e-203 K helix_turn _helix lactose operon repressor
LCLEADBE_00313 2.2e-247 gutA G Psort location CytoplasmicMembrane, score 10.00
LCLEADBE_00314 0.0 uidA G Belongs to the glycosyl hydrolase 2 family
LCLEADBE_00315 2.1e-61 L Transposase
LCLEADBE_00316 1.4e-151 tnp7109-2 L PFAM Transposase, Mutator family
LCLEADBE_00317 1.6e-152 L Phage integrase, N-terminal SAM-like domain
LCLEADBE_00318 4.9e-47 insK L Integrase core domain
LCLEADBE_00319 1e-63 tyrA 5.4.99.5 E Chorismate mutase type II
LCLEADBE_00320 0.0 S domain protein
LCLEADBE_00321 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LCLEADBE_00322 1.2e-288 E Bacterial extracellular solute-binding proteins, family 5 Middle
LCLEADBE_00323 7.9e-128 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCLEADBE_00324 1.8e-139 KT Transcriptional regulatory protein, C terminal
LCLEADBE_00325 7.1e-119
LCLEADBE_00326 1.3e-97 mntP P Probably functions as a manganese efflux pump
LCLEADBE_00327 4e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LCLEADBE_00328 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
LCLEADBE_00329 0.0 K RNA polymerase II activating transcription factor binding
LCLEADBE_00330 7.7e-19 M Glycosyl hydrolases family 25
LCLEADBE_00331 1.9e-25 M Glycosyl hydrolases family 25
LCLEADBE_00332 1.9e-43 S Putative phage holin Dp-1
LCLEADBE_00333 2.7e-38
LCLEADBE_00335 6e-54 L Phage integrase family
LCLEADBE_00336 1.2e-08 L IstB-like ATP binding protein
LCLEADBE_00337 4.7e-56 L IstB-like ATP binding protein
LCLEADBE_00338 3.9e-289 L PFAM Integrase catalytic
LCLEADBE_00339 6.3e-43 L Transposase and inactivated derivatives IS30 family
LCLEADBE_00340 2e-180 P Binding-protein-dependent transport system inner membrane component
LCLEADBE_00341 1.4e-167 G Binding-protein-dependent transport system inner membrane component
LCLEADBE_00342 0.0 G transport
LCLEADBE_00343 6e-252 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
LCLEADBE_00344 2.2e-117 S Protein of unknown function, DUF624
LCLEADBE_00345 1.5e-121 K Bacterial regulatory proteins, tetR family
LCLEADBE_00346 1e-85 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
LCLEADBE_00347 4.8e-284 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
LCLEADBE_00348 0.0 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
LCLEADBE_00349 2.1e-201 L Helix-turn-helix domain
LCLEADBE_00350 2e-252 L Transposase, Mutator family
LCLEADBE_00353 3e-116
LCLEADBE_00355 1.7e-08 S Phage portal protein, SPP1 Gp6-like
LCLEADBE_00356 1.3e-120 S Phage portal protein, SPP1 Gp6-like
LCLEADBE_00357 1.9e-261
LCLEADBE_00359 5.4e-17
LCLEADBE_00360 8.1e-160 S Phage capsid family
LCLEADBE_00362 3.2e-36 S Putative phage holin Dp-1
LCLEADBE_00363 2.8e-61
LCLEADBE_00364 2.7e-28
LCLEADBE_00365 8.8e-153 L Phage integrase family
LCLEADBE_00367 1.6e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LCLEADBE_00368 6.4e-148 atpB C it plays a direct role in the translocation of protons across the membrane
LCLEADBE_00369 4.4e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCLEADBE_00370 1.4e-63 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LCLEADBE_00371 2.2e-151 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCLEADBE_00372 1.3e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LCLEADBE_00373 5.5e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LCLEADBE_00374 2.1e-282 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LCLEADBE_00375 3.2e-49 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LCLEADBE_00376 1.4e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LCLEADBE_00377 5.5e-159 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
LCLEADBE_00378 3e-189
LCLEADBE_00379 4.2e-181
LCLEADBE_00380 1.1e-164 trxA2 O Tetratricopeptide repeat
LCLEADBE_00381 6.9e-118 cyaA 4.6.1.1 S CYTH
LCLEADBE_00384 3.6e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
LCLEADBE_00385 2.3e-189 plsC2 2.3.1.51 I Phosphate acyltransferases
LCLEADBE_00386 2.7e-180 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
LCLEADBE_00387 9.8e-230 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LCLEADBE_00388 4e-220 P Bacterial extracellular solute-binding protein
LCLEADBE_00389 3.4e-161 U Binding-protein-dependent transport system inner membrane component
LCLEADBE_00390 1.4e-151 U Binding-protein-dependent transport system inner membrane component
LCLEADBE_00391 1.5e-239 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LCLEADBE_00392 1.1e-187 S CAAX protease self-immunity
LCLEADBE_00393 3.4e-138 M Mechanosensitive ion channel
LCLEADBE_00394 1.7e-273 aspA 4.3.1.1 E Fumarase C C-terminus
LCLEADBE_00395 6e-10 L Transposase DDE domain
LCLEADBE_00396 1.8e-134 S Sulfite exporter TauE/SafE
LCLEADBE_00397 9.5e-263 aslB C Iron-sulfur cluster-binding domain
LCLEADBE_00398 9.1e-195 K helix_turn _helix lactose operon repressor
LCLEADBE_00399 1.6e-306 Z012_09690 P Domain of unknown function (DUF4976)
LCLEADBE_00400 1.5e-266 G Bacterial extracellular solute-binding protein
LCLEADBE_00401 2.9e-165 malC P Binding-protein-dependent transport system inner membrane component
LCLEADBE_00402 1.6e-177 P Binding-protein-dependent transport system inner membrane component
LCLEADBE_00403 2.2e-237 S AAA domain
LCLEADBE_00404 3.9e-41 L Transposase, Mutator family
LCLEADBE_00405 1.3e-106 K Bacterial regulatory proteins, tetR family
LCLEADBE_00406 1.9e-258 MA20_36090 S Psort location Cytoplasmic, score 8.87
LCLEADBE_00407 3.6e-93 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LCLEADBE_00408 9.4e-83 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LCLEADBE_00409 6.4e-81 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
LCLEADBE_00410 5e-117 P Sodium/hydrogen exchanger family
LCLEADBE_00412 1.6e-22
LCLEADBE_00413 2.8e-81
LCLEADBE_00414 0.0 Q von Willebrand factor (vWF) type A domain
LCLEADBE_00415 6e-280 M LPXTG cell wall anchor motif
LCLEADBE_00417 3.8e-87
LCLEADBE_00418 2.6e-110
LCLEADBE_00419 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LCLEADBE_00420 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LCLEADBE_00421 3.2e-127 V ABC transporter, ATP-binding protein
LCLEADBE_00422 1.9e-63 macB_7 V FtsX-like permease family
LCLEADBE_00423 9.8e-90 lemA S LemA family
LCLEADBE_00424 0.0 S Predicted membrane protein (DUF2207)
LCLEADBE_00425 2.1e-09 S Predicted membrane protein (DUF2207)
LCLEADBE_00426 5.4e-246 S Predicted membrane protein (DUF2207)
LCLEADBE_00427 1e-23
LCLEADBE_00428 3.7e-170 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
LCLEADBE_00429 1.6e-204 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
LCLEADBE_00430 2.2e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LCLEADBE_00431 1e-34 CP_0960 S Belongs to the UPF0109 family
LCLEADBE_00432 7e-62 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LCLEADBE_00433 1.5e-215 S Endonuclease/Exonuclease/phosphatase family
LCLEADBE_00434 6.9e-266 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LCLEADBE_00435 2.3e-162 P Cation efflux family
LCLEADBE_00436 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
LCLEADBE_00437 3.5e-137 guaA1 6.3.5.2 F Peptidase C26
LCLEADBE_00438 0.0 yjjK S ABC transporter
LCLEADBE_00439 2.1e-73 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
LCLEADBE_00440 3.9e-44 stbC S Plasmid stability protein
LCLEADBE_00441 4e-93 ilvN 2.2.1.6 E ACT domain
LCLEADBE_00442 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
LCLEADBE_00443 9.7e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LCLEADBE_00444 9.3e-21 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LCLEADBE_00445 7.6e-117 yceD S Uncharacterized ACR, COG1399
LCLEADBE_00446 7.9e-87
LCLEADBE_00447 6e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LCLEADBE_00448 2.4e-49 S Protein of unknown function (DUF3039)
LCLEADBE_00449 1.9e-197 yghZ C Aldo/keto reductase family
LCLEADBE_00450 6.3e-78 soxR K MerR, DNA binding
LCLEADBE_00451 3.7e-119
LCLEADBE_00452 8.5e-251 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCLEADBE_00453 1.1e-144 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LCLEADBE_00454 1.3e-137 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LCLEADBE_00455 7.3e-178 S Auxin Efflux Carrier
LCLEADBE_00458 0.0 pgi 5.3.1.9 G Belongs to the GPI family
LCLEADBE_00459 1.3e-265 abcT3 P ATPases associated with a variety of cellular activities
LCLEADBE_00460 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
LCLEADBE_00461 6.6e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LCLEADBE_00462 2.7e-166 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LCLEADBE_00463 2.4e-161 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCLEADBE_00464 1.9e-211 K helix_turn _helix lactose operon repressor
LCLEADBE_00465 0.0 fadD 6.2.1.3 I AMP-binding enzyme
LCLEADBE_00466 3.2e-40 araE EGP Major facilitator Superfamily
LCLEADBE_00467 1e-20 araE EGP Major facilitator Superfamily
LCLEADBE_00468 0.0 cydD V ABC transporter transmembrane region
LCLEADBE_00469 3.2e-261 G Bacterial extracellular solute-binding protein
LCLEADBE_00470 3.9e-173 malC G Binding-protein-dependent transport system inner membrane component
LCLEADBE_00471 4.4e-167 G ABC transporter permease
LCLEADBE_00472 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
LCLEADBE_00473 5.5e-192 K helix_turn _helix lactose operon repressor
LCLEADBE_00474 0.0 ganB 3.2.1.89 G Glycosyl hydrolase family 53
LCLEADBE_00475 2e-168 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
LCLEADBE_00476 2.9e-142 L Protein of unknown function (DUF1524)
LCLEADBE_00477 4.6e-236 mntH P H( )-stimulated, divalent metal cation uptake system
LCLEADBE_00478 7.1e-284 EGP Major facilitator Superfamily
LCLEADBE_00479 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
LCLEADBE_00480 0.0 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
LCLEADBE_00481 3e-110 3.1.3.48 T Low molecular weight phosphatase family
LCLEADBE_00482 6.1e-76 L PFAM Integrase catalytic
LCLEADBE_00483 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_00484 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_00485 9.4e-19 L PFAM Integrase catalytic
LCLEADBE_00486 1.3e-263 S Psort location CytoplasmicMembrane, score 9.99
LCLEADBE_00487 2.4e-172 H Core-2/I-Branching enzyme
LCLEADBE_00489 4.9e-84 wcaB 2.3.1.30 E serine acetyltransferase
LCLEADBE_00490 1.8e-192 M Glycosyl transferase, family 2
LCLEADBE_00491 1.8e-186 MA20_43635 M Capsular polysaccharide synthesis protein
LCLEADBE_00492 1.5e-155 cps1D M Domain of unknown function (DUF4422)
LCLEADBE_00493 1.2e-202 M Psort location Cytoplasmic, score 8.87
LCLEADBE_00494 1.8e-209 GT4 M Psort location Cytoplasmic, score 8.87
LCLEADBE_00495 1.4e-245 MA20_17390 GT4 M Glycosyl transferases group 1
LCLEADBE_00496 1.5e-253 cps2J S Polysaccharide biosynthesis protein
LCLEADBE_00497 8.3e-201 2.4.1.166 GT2 M Glycosyltransferase like family 2
LCLEADBE_00498 5.1e-133 H Hexapeptide repeat of succinyl-transferase
LCLEADBE_00499 1e-212 S Polysaccharide pyruvyl transferase
LCLEADBE_00500 5.8e-188 M Glycosyltransferase like family 2
LCLEADBE_00502 2e-194 wzy S EpsG family
LCLEADBE_00503 1.6e-191 G Acyltransferase family
LCLEADBE_00505 1.4e-150 L IstB-like ATP binding protein
LCLEADBE_00506 1.6e-42 L Transposase
LCLEADBE_00507 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_00508 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_00509 4.2e-266 L Transposase
LCLEADBE_00511 8.1e-246 S KAP family P-loop domain
LCLEADBE_00513 2.8e-37 L PFAM Integrase catalytic
LCLEADBE_00514 5.1e-07 L Transposase
LCLEADBE_00516 1.3e-35 L PFAM Integrase catalytic
LCLEADBE_00517 1.2e-28 L PFAM Integrase catalytic
LCLEADBE_00518 6.8e-25 L PFAM Integrase catalytic
LCLEADBE_00519 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_00520 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_00521 3.4e-28 L Transposase
LCLEADBE_00522 0.0 C Domain of unknown function (DUF4365)
LCLEADBE_00523 3e-50 S Bacteriophage abortive infection AbiH
LCLEADBE_00525 2.7e-88 K Helix-turn-helix XRE-family like proteins
LCLEADBE_00527 2.3e-48 S enterobacterial common antigen metabolic process
LCLEADBE_00528 3.5e-99 S enterobacterial common antigen metabolic process
LCLEADBE_00529 1.6e-41 S Protein of unknown function (DUF3800)
LCLEADBE_00530 8.3e-14 L Helix-turn-helix domain
LCLEADBE_00531 5.8e-266 S Psort location CytoplasmicMembrane, score 9.99
LCLEADBE_00532 8.3e-70
LCLEADBE_00533 9e-246 wcoI DM Psort location CytoplasmicMembrane, score
LCLEADBE_00534 4.7e-172
LCLEADBE_00535 3.1e-173 S G5
LCLEADBE_00536 1.9e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
LCLEADBE_00537 1.6e-120 F Domain of unknown function (DUF4916)
LCLEADBE_00538 7.6e-160 mhpC I Alpha/beta hydrolase family
LCLEADBE_00539 9.4e-215 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
LCLEADBE_00540 5.9e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
LCLEADBE_00541 2.5e-225 S Uncharacterized conserved protein (DUF2183)
LCLEADBE_00542 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
LCLEADBE_00543 4.9e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LCLEADBE_00544 4.3e-222 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
LCLEADBE_00545 2.1e-134 glxR K helix_turn_helix, cAMP Regulatory protein
LCLEADBE_00546 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
LCLEADBE_00547 6.1e-233 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
LCLEADBE_00548 6.1e-229 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
LCLEADBE_00549 2.8e-123 glpR K DeoR C terminal sensor domain
LCLEADBE_00550 6.6e-253 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
LCLEADBE_00551 5.3e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
LCLEADBE_00552 6.4e-44 gcvR T Belongs to the UPF0237 family
LCLEADBE_00553 3.2e-253 S UPF0210 protein
LCLEADBE_00554 7.6e-115 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LCLEADBE_00555 3.7e-187 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
LCLEADBE_00556 6.1e-129
LCLEADBE_00557 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCLEADBE_00558 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCLEADBE_00559 0.0 E Transglutaminase-like superfamily
LCLEADBE_00560 2.5e-239 S Protein of unknown function DUF58
LCLEADBE_00561 0.0 S Fibronectin type 3 domain
LCLEADBE_00562 1.3e-223 KLT Protein tyrosine kinase
LCLEADBE_00563 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
LCLEADBE_00564 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
LCLEADBE_00565 7.8e-236 G Major Facilitator Superfamily
LCLEADBE_00566 1.7e-134 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LCLEADBE_00567 1.7e-162 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LCLEADBE_00568 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LCLEADBE_00569 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
LCLEADBE_00570 8.9e-259 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCLEADBE_00571 4.4e-123 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LCLEADBE_00572 2.3e-273 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
LCLEADBE_00573 4.2e-206 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LCLEADBE_00574 4.4e-206 ftsE D Cell division ATP-binding protein FtsE
LCLEADBE_00575 9.8e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
LCLEADBE_00576 8.1e-148 usp 3.5.1.28 CBM50 D CHAP domain protein
LCLEADBE_00577 2.2e-79 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LCLEADBE_00578 1.5e-143 pknD ET ABC transporter, substrate-binding protein, family 3
LCLEADBE_00579 3.4e-169 pknD ET ABC transporter, substrate-binding protein, family 3
LCLEADBE_00580 1.6e-153 yecS E Binding-protein-dependent transport system inner membrane component
LCLEADBE_00581 2.2e-151 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
LCLEADBE_00582 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LCLEADBE_00583 3.6e-142 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
LCLEADBE_00584 3.9e-187 K Periplasmic binding protein domain
LCLEADBE_00585 2.6e-169 malC G Binding-protein-dependent transport system inner membrane component
LCLEADBE_00586 9.5e-170 G ABC transporter permease
LCLEADBE_00587 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
LCLEADBE_00588 1.7e-259 G Bacterial extracellular solute-binding protein
LCLEADBE_00589 4.7e-279 G Bacterial extracellular solute-binding protein
LCLEADBE_00590 4.1e-144 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LCLEADBE_00591 2.9e-293 E ABC transporter, substrate-binding protein, family 5
LCLEADBE_00592 6.7e-168 P Binding-protein-dependent transport system inner membrane component
LCLEADBE_00593 1.7e-150 EP Binding-protein-dependent transport system inner membrane component
LCLEADBE_00594 4.9e-137 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
LCLEADBE_00595 2e-138 sapF E ATPases associated with a variety of cellular activities
LCLEADBE_00596 9.7e-194 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
LCLEADBE_00597 2.2e-221 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
LCLEADBE_00598 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
LCLEADBE_00599 2.7e-93 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LCLEADBE_00600 1.7e-104 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCLEADBE_00601 1.1e-272 yhdG E aromatic amino acid transport protein AroP K03293
LCLEADBE_00602 1.4e-264 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LCLEADBE_00603 3.1e-245 dgt 3.1.5.1 F Phosphohydrolase-associated domain
LCLEADBE_00604 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LCLEADBE_00605 1.8e-69 S PIN domain
LCLEADBE_00606 1e-34
LCLEADBE_00607 1.4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LCLEADBE_00608 1.1e-115 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LCLEADBE_00609 9.1e-297 EK Alanine-glyoxylate amino-transferase
LCLEADBE_00610 1e-210 ybiR P Citrate transporter
LCLEADBE_00611 3.3e-30
LCLEADBE_00612 7e-43 G Alpha-L-arabinofuranosidase C-terminal domain
LCLEADBE_00613 1.3e-159 K Helix-turn-helix domain, rpiR family
LCLEADBE_00616 6.6e-259 G Bacterial extracellular solute-binding protein
LCLEADBE_00617 9.9e-225 K helix_turn _helix lactose operon repressor
LCLEADBE_00618 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
LCLEADBE_00619 2e-13 L Psort location Cytoplasmic, score 8.87
LCLEADBE_00620 0.0 E ABC transporter, substrate-binding protein, family 5
LCLEADBE_00621 8.5e-87 msrA 1.8.4.11, 1.8.4.12 O peptide-methionine (S)-S-oxide reductase activity
LCLEADBE_00622 2.1e-135 V ATPases associated with a variety of cellular activities
LCLEADBE_00623 1.2e-188 M Conserved repeat domain
LCLEADBE_00624 3.3e-286 macB_8 V MacB-like periplasmic core domain
LCLEADBE_00625 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LCLEADBE_00626 9.8e-183 adh3 C Zinc-binding dehydrogenase
LCLEADBE_00627 4.3e-86 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LCLEADBE_00628 4.2e-225 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LCLEADBE_00629 1.2e-68 zur P Belongs to the Fur family
LCLEADBE_00630 4.4e-84 ylbB V FtsX-like permease family
LCLEADBE_00631 2.9e-27 ylbB V FtsX-like permease family
LCLEADBE_00632 1.2e-68 XK27_06785 V ABC transporter
LCLEADBE_00633 2.9e-45 tetR K Transcriptional regulator C-terminal region
LCLEADBE_00634 6.5e-65
LCLEADBE_00635 1.1e-84 zur P Ferric uptake regulator family
LCLEADBE_00636 3.5e-140 S TIGRFAM TIGR03943 family protein
LCLEADBE_00637 3.2e-182 ycgR S Predicted permease
LCLEADBE_00639 7.3e-156 P Zinc-uptake complex component A periplasmic
LCLEADBE_00640 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
LCLEADBE_00641 1.5e-299 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
LCLEADBE_00642 7.4e-244 purD 6.3.4.13 F Belongs to the GARS family
LCLEADBE_00643 3.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LCLEADBE_00644 9.3e-294 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LCLEADBE_00645 1.2e-302 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
LCLEADBE_00646 5.4e-33
LCLEADBE_00647 3.7e-12 C Aldo/keto reductase family
LCLEADBE_00648 1.1e-102 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
LCLEADBE_00649 2.4e-08 S Protein of unknown function (DUF4230)
LCLEADBE_00652 1.5e-29 S Protein of unknown function (DUF4230)
LCLEADBE_00653 1.9e-144
LCLEADBE_00654 3.8e-114 Q D-alanine [D-alanyl carrier protein] ligase activity
LCLEADBE_00655 1.6e-260 Q D-alanine [D-alanyl carrier protein] ligase activity
LCLEADBE_00656 1.8e-240 I alpha/beta hydrolase fold
LCLEADBE_00657 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
LCLEADBE_00658 1.5e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LCLEADBE_00659 3.6e-225 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LCLEADBE_00660 6.4e-232 mtnE 2.6.1.83 E Aminotransferase class I and II
LCLEADBE_00661 2.8e-221 M Glycosyl transferase 4-like domain
LCLEADBE_00662 4.2e-197 ltaE 4.1.2.48 E Beta-eliminating lyase
LCLEADBE_00664 1.3e-193 yocS S SBF-like CPA transporter family (DUF4137)
LCLEADBE_00665 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LCLEADBE_00666 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LCLEADBE_00667 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LCLEADBE_00668 6.2e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LCLEADBE_00669 7e-130 tmp1 S Domain of unknown function (DUF4391)
LCLEADBE_00670 7.1e-147 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
LCLEADBE_00671 2.7e-186 MA20_14895 S Conserved hypothetical protein 698
LCLEADBE_00673 6.3e-21 S Psort location CytoplasmicMembrane, score
LCLEADBE_00674 1.2e-28 S polysaccharide biosynthetic process
LCLEADBE_00675 1.3e-60 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCLEADBE_00676 1.6e-91 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCLEADBE_00677 1.2e-77 K MerR family regulatory protein
LCLEADBE_00678 3.9e-198 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
LCLEADBE_00679 3.8e-262 S Domain of unknown function (DUF4143)
LCLEADBE_00680 2.4e-110 P Protein of unknown function DUF47
LCLEADBE_00681 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCLEADBE_00682 1.4e-243 vbsD V MatE
LCLEADBE_00683 6.2e-128 magIII L endonuclease III
LCLEADBE_00684 1.1e-14 laaE K Transcriptional regulator PadR-like family
LCLEADBE_00685 1.2e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
LCLEADBE_00686 2.9e-41 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
LCLEADBE_00687 3.7e-188 S Membrane transport protein
LCLEADBE_00688 7.4e-48 4.1.1.44 L Cupin 2, conserved barrel domain protein
LCLEADBE_00690 0.0 M probably involved in cell wall
LCLEADBE_00691 1.1e-253 3.2.1.14 GH18 S Carbohydrate binding domain
LCLEADBE_00692 0.0 T Diguanylate cyclase, GGDEF domain
LCLEADBE_00693 3.2e-136 ybbM V Uncharacterised protein family (UPF0014)
LCLEADBE_00694 8.1e-131 ybbL V ATPases associated with a variety of cellular activities
LCLEADBE_00695 3.9e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LCLEADBE_00696 1.7e-93 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCLEADBE_00697 6.7e-242 carA 6.3.5.5 F Belongs to the CarA family
LCLEADBE_00698 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
LCLEADBE_00699 6.7e-170 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
LCLEADBE_00700 2.9e-105 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
LCLEADBE_00701 2.2e-136 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
LCLEADBE_00703 0.0 tetP J Elongation factor G, domain IV
LCLEADBE_00704 7.1e-127 ypfH S Phospholipase/Carboxylesterase
LCLEADBE_00705 1e-234 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
LCLEADBE_00706 2.5e-42 XAC3035 O Glutaredoxin
LCLEADBE_00707 2.7e-08 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
LCLEADBE_00708 7.2e-116 XK27_08050 O prohibitin homologues
LCLEADBE_00709 1.1e-58 S Domain of unknown function (DUF4143)
LCLEADBE_00710 2.9e-159 S Patatin-like phospholipase
LCLEADBE_00711 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LCLEADBE_00712 2.7e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
LCLEADBE_00713 3.8e-128 S Vitamin K epoxide reductase
LCLEADBE_00714 6.5e-170 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
LCLEADBE_00715 7.2e-33 S Protein of unknown function (DUF3107)
LCLEADBE_00716 2e-302 mphA S Aminoglycoside phosphotransferase
LCLEADBE_00717 4e-292 uvrD2 3.6.4.12 L DNA helicase
LCLEADBE_00718 1.2e-297 S Zincin-like metallopeptidase
LCLEADBE_00719 3.5e-158 lon T Belongs to the peptidase S16 family
LCLEADBE_00720 1.6e-73 S Protein of unknown function (DUF3052)
LCLEADBE_00722 2.3e-210 2.7.11.1 NU Tfp pilus assembly protein FimV
LCLEADBE_00723 5.7e-222 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LCLEADBE_00724 5.3e-231 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LCLEADBE_00725 0.0 I acetylesterase activity
LCLEADBE_00726 4.5e-129 recO L Involved in DNA repair and RecF pathway recombination
LCLEADBE_00727 3.1e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LCLEADBE_00728 1.2e-135 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
LCLEADBE_00729 6.1e-191 P NMT1/THI5 like
LCLEADBE_00730 3.9e-226 E Aminotransferase class I and II
LCLEADBE_00731 6.1e-143 bioM P ATPases associated with a variety of cellular activities
LCLEADBE_00733 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LCLEADBE_00734 0.0 S Tetratricopeptide repeat
LCLEADBE_00735 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LCLEADBE_00736 1.4e-206 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LCLEADBE_00737 2.3e-281 glnA 6.3.1.2 E glutamine synthetase
LCLEADBE_00738 9.2e-144 S Domain of unknown function (DUF4191)
LCLEADBE_00739 3.4e-280 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCLEADBE_00740 6.9e-102 S Protein of unknown function (DUF3043)
LCLEADBE_00741 9.4e-261 argE E Peptidase dimerisation domain
LCLEADBE_00742 6.2e-108 ykoE S ABC-type cobalt transport system, permease component
LCLEADBE_00743 1.2e-280 ykoD P ATPases associated with a variety of cellular activities
LCLEADBE_00744 1.8e-165 cbiQ P Cobalt transport protein
LCLEADBE_00745 4.9e-162 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCLEADBE_00746 7.7e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LCLEADBE_00747 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
LCLEADBE_00748 7.1e-105
LCLEADBE_00749 5.3e-206 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LCLEADBE_00750 2.6e-214 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LCLEADBE_00751 2.2e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LCLEADBE_00752 2.4e-250 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
LCLEADBE_00753 3.9e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LCLEADBE_00754 5.9e-83 argR K Regulates arginine biosynthesis genes
LCLEADBE_00755 1.2e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LCLEADBE_00756 4.1e-24 L Transposase
LCLEADBE_00757 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_00758 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_00759 3.8e-19 L Transposase
LCLEADBE_00760 3.4e-31 L PFAM Integrase catalytic
LCLEADBE_00761 8.5e-44 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
LCLEADBE_00762 2.4e-32 relB L RelB antitoxin
LCLEADBE_00763 3e-281 argH 4.3.2.1 E argininosuccinate lyase
LCLEADBE_00764 1.2e-28 thiS 2.8.1.10 H ThiS family
LCLEADBE_00765 2.5e-158 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LCLEADBE_00766 2e-146 moeB 2.7.7.80 H ThiF family
LCLEADBE_00767 3.1e-71 M1-798 P Rhodanese Homology Domain
LCLEADBE_00768 4.6e-102 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
LCLEADBE_00769 3.9e-139 S Putative ABC-transporter type IV
LCLEADBE_00770 0.0 S Protein of unknown function (DUF975)
LCLEADBE_00771 2.6e-255 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LCLEADBE_00772 3.8e-172 L Tetratricopeptide repeat
LCLEADBE_00773 3.2e-200 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LCLEADBE_00775 1.1e-141 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LCLEADBE_00776 1.6e-96
LCLEADBE_00777 9e-69 trkA P TrkA-N domain
LCLEADBE_00778 8.3e-12 trkB P Cation transport protein
LCLEADBE_00779 1.8e-184 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LCLEADBE_00780 0.0 recN L May be involved in recombinational repair of damaged DNA
LCLEADBE_00781 6.3e-122 S Haloacid dehalogenase-like hydrolase
LCLEADBE_00782 6e-13 J Acetyltransferase (GNAT) domain
LCLEADBE_00783 2.3e-18 J Acetyltransferase (GNAT) domain
LCLEADBE_00784 4.8e-58 K helix_turn_helix gluconate operon transcriptional repressor
LCLEADBE_00785 1.1e-172 V ATPases associated with a variety of cellular activities
LCLEADBE_00786 4.5e-121 S ABC-2 family transporter protein
LCLEADBE_00787 7.9e-110
LCLEADBE_00788 3.7e-27 S Psort location Cytoplasmic, score
LCLEADBE_00789 3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
LCLEADBE_00790 6.2e-238 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LCLEADBE_00791 1.9e-98
LCLEADBE_00792 3.2e-138 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LCLEADBE_00793 1.7e-91 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
LCLEADBE_00794 5.9e-24 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
LCLEADBE_00795 0.0 S Uncharacterised protein family (UPF0182)
LCLEADBE_00796 4.1e-93 2.3.1.183 M Acetyltransferase (GNAT) domain
LCLEADBE_00797 1.5e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LCLEADBE_00798 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LCLEADBE_00799 1.1e-180 1.1.1.65 C Aldo/keto reductase family
LCLEADBE_00800 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LCLEADBE_00801 6.6e-70 divIC D Septum formation initiator
LCLEADBE_00802 1.3e-102 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
LCLEADBE_00803 8.9e-184 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
LCLEADBE_00805 7.5e-95
LCLEADBE_00806 1.2e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
LCLEADBE_00807 1.4e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
LCLEADBE_00808 4.4e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LCLEADBE_00809 9.7e-148 yplQ S Haemolysin-III related
LCLEADBE_00810 7.5e-280 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
LCLEADBE_00811 4.9e-47 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
LCLEADBE_00812 0.0 D FtsK/SpoIIIE family
LCLEADBE_00813 1.3e-206 K Cell envelope-related transcriptional attenuator domain
LCLEADBE_00814 1.8e-55 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
LCLEADBE_00815 0.0 S Glycosyl transferase, family 2
LCLEADBE_00816 7.9e-264
LCLEADBE_00817 5.7e-79 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
LCLEADBE_00818 3.6e-151 cof 5.2.1.8 T Eukaryotic phosphomannomutase
LCLEADBE_00819 2.2e-122 ctsW S Phosphoribosyl transferase domain
LCLEADBE_00820 4.4e-197 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
LCLEADBE_00821 4.5e-129 T Response regulator receiver domain protein
LCLEADBE_00822 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LCLEADBE_00823 2.1e-100 carD K CarD-like/TRCF domain
LCLEADBE_00824 2.1e-88 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LCLEADBE_00825 4e-137 znuB U ABC 3 transport family
LCLEADBE_00826 3.8e-162 znuC P ATPases associated with a variety of cellular activities
LCLEADBE_00827 4.2e-185 P Zinc-uptake complex component A periplasmic
LCLEADBE_00828 3.1e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LCLEADBE_00829 3.2e-254 rpsA J Ribosomal protein S1
LCLEADBE_00830 5.5e-116 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LCLEADBE_00831 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LCLEADBE_00832 2.1e-177 terC P Integral membrane protein, TerC family
LCLEADBE_00833 2.4e-275 pyk 2.7.1.40 G Pyruvate kinase
LCLEADBE_00834 1.1e-109 aspA 3.6.1.13 L NUDIX domain
LCLEADBE_00836 2.8e-124 pdtaR T Response regulator receiver domain protein
LCLEADBE_00837 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCLEADBE_00838 4.7e-179 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
LCLEADBE_00839 4e-127 3.6.1.13 L NUDIX domain
LCLEADBE_00840 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
LCLEADBE_00841 1.4e-24 zntR K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LCLEADBE_00842 3.6e-90 K Putative zinc ribbon domain
LCLEADBE_00843 2.1e-125 S GyrI-like small molecule binding domain
LCLEADBE_00845 1.2e-20 tag 3.2.2.20 L Methyladenine glycosylase
LCLEADBE_00847 7e-124
LCLEADBE_00848 1.9e-214 ykiI
LCLEADBE_00849 8.1e-257 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LCLEADBE_00850 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LCLEADBE_00851 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LCLEADBE_00853 1.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCLEADBE_00854 0.0 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
LCLEADBE_00855 4.3e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LCLEADBE_00856 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
LCLEADBE_00857 3.5e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LCLEADBE_00858 6.5e-66 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LCLEADBE_00859 2.7e-134 3.1.3.85 G Phosphoglycerate mutase family
LCLEADBE_00862 5.6e-158 S Sucrose-6F-phosphate phosphohydrolase
LCLEADBE_00863 6.5e-179 metQ P NLPA lipoprotein
LCLEADBE_00864 1.4e-220 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LCLEADBE_00865 3.3e-113 metI P Binding-protein-dependent transport system inner membrane component
LCLEADBE_00866 1.5e-227 S Peptidase dimerisation domain
LCLEADBE_00867 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LCLEADBE_00868 1.8e-39
LCLEADBE_00869 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
LCLEADBE_00870 8.7e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCLEADBE_00871 9.5e-123 S Protein of unknown function (DUF3000)
LCLEADBE_00872 6.2e-254 rnd 3.1.13.5 J 3'-5' exonuclease
LCLEADBE_00873 4.4e-234 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LCLEADBE_00874 4.6e-247 clcA_2 P Voltage gated chloride channel
LCLEADBE_00875 5.2e-60
LCLEADBE_00876 6.5e-116 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LCLEADBE_00877 1.1e-121 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LCLEADBE_00878 2.1e-252 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LCLEADBE_00881 1.3e-242 patB 4.4.1.8 E Aminotransferase, class I II
LCLEADBE_00882 7.9e-239 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LCLEADBE_00883 1.6e-168 fmt2 3.2.2.10 S Belongs to the LOG family
LCLEADBE_00884 4.5e-115 safC S O-methyltransferase
LCLEADBE_00885 1.1e-183 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
LCLEADBE_00886 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
LCLEADBE_00887 0.0 dprA 5.99.1.2 LU DNA recombination-mediator protein A
LCLEADBE_00888 6.8e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
LCLEADBE_00889 5.7e-76 yraN L Belongs to the UPF0102 family
LCLEADBE_00890 3.6e-23 L Transposase and inactivated derivatives IS30 family
LCLEADBE_00891 7.3e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
LCLEADBE_00892 4.5e-252 metY 2.5.1.49 E Aminotransferase class-V
LCLEADBE_00893 1.4e-170 V ABC transporter, ATP-binding protein
LCLEADBE_00894 0.0 MV MacB-like periplasmic core domain
LCLEADBE_00895 4.5e-141 K helix_turn_helix, Lux Regulon
LCLEADBE_00896 0.0 tcsS2 T Histidine kinase
LCLEADBE_00897 4.1e-294 pip 3.4.11.5 S alpha/beta hydrolase fold
LCLEADBE_00898 1.4e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCLEADBE_00899 1.8e-156 cjaA ET Bacterial periplasmic substrate-binding proteins
LCLEADBE_00900 1.2e-138 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
LCLEADBE_00901 1.2e-118 E Binding-protein-dependent transport system inner membrane component
LCLEADBE_00902 6.7e-111 papP E Binding-protein-dependent transport system inner membrane component
LCLEADBE_00903 1.7e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LCLEADBE_00904 1.4e-164 K Arac family
LCLEADBE_00905 2.7e-35 S rRNA binding
LCLEADBE_00907 9.2e-248 V MatE
LCLEADBE_00908 0.0 drrC L ABC transporter
LCLEADBE_00909 1.4e-26 2.7.7.7 L Transposase, Mutator family
LCLEADBE_00910 1.7e-235 XK27_00240 K Fic/DOC family
LCLEADBE_00911 4.1e-60 yccF S Inner membrane component domain
LCLEADBE_00912 1.3e-159 ksgA 2.1.1.182 J Methyltransferase domain
LCLEADBE_00913 2.5e-67 S Cupin 2, conserved barrel domain protein
LCLEADBE_00914 1.5e-52 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
LCLEADBE_00915 1.1e-37 L RelB antitoxin
LCLEADBE_00916 2.5e-244 S HipA-like C-terminal domain
LCLEADBE_00917 2.4e-17 K addiction module antidote protein HigA
LCLEADBE_00918 8.9e-221 G Transmembrane secretion effector
LCLEADBE_00919 2e-30 K Bacterial regulatory proteins, tetR family
LCLEADBE_00920 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_00921 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_00922 8.5e-80 K Bacterial regulatory proteins, tetR family
LCLEADBE_00923 7.3e-59 yccF S Inner membrane component domain
LCLEADBE_00924 2.2e-11
LCLEADBE_00925 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
LCLEADBE_00926 3.2e-295 KLT Protein tyrosine kinase
LCLEADBE_00927 6.5e-78 K Psort location Cytoplasmic, score
LCLEADBE_00928 1.4e-231
LCLEADBE_00929 1e-37
LCLEADBE_00930 1.5e-198 S Short C-terminal domain
LCLEADBE_00931 8.3e-75 M Excalibur calcium-binding domain
LCLEADBE_00932 4.7e-94 S Helix-turn-helix
LCLEADBE_00933 4.8e-25 L Transposase and inactivated derivatives IS30 family
LCLEADBE_00934 1.9e-224 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LCLEADBE_00935 7.3e-244 nagA 3.5.1.25 G Amidohydrolase family
LCLEADBE_00936 1.9e-147 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LCLEADBE_00937 8.7e-176 2.7.1.2 GK ROK family
LCLEADBE_00938 1.4e-220 GK ROK family
LCLEADBE_00939 4.4e-160 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
LCLEADBE_00940 7.5e-253 gtr U Sugar (and other) transporter
LCLEADBE_00941 0.0 P Domain of unknown function (DUF4976)
LCLEADBE_00942 4e-272 aslB C Iron-sulfur cluster-binding domain
LCLEADBE_00943 3.2e-107 S Sulfite exporter TauE/SafE
LCLEADBE_00944 5.7e-61 L Helix-turn-helix domain
LCLEADBE_00945 2.5e-89 S Sulfite exporter TauE/SafE
LCLEADBE_00946 1.7e-63 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LCLEADBE_00948 7.3e-245 EGP Major facilitator Superfamily
LCLEADBE_00949 1.6e-108 3.1.3.27 E haloacid dehalogenase-like hydrolase
LCLEADBE_00950 4.7e-162 3.1.3.73 G Phosphoglycerate mutase family
LCLEADBE_00951 1.2e-236 rutG F Permease family
LCLEADBE_00952 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
LCLEADBE_00953 3.4e-260 nplT G Alpha amylase, catalytic domain
LCLEADBE_00954 9.8e-189 pit P Phosphate transporter family
LCLEADBE_00955 2.1e-114 MA20_27875 P Protein of unknown function DUF47
LCLEADBE_00956 8.3e-114 K helix_turn_helix, Lux Regulon
LCLEADBE_00957 9.3e-245 T Histidine kinase
LCLEADBE_00958 1.3e-120 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
LCLEADBE_00959 1.3e-187 V ATPases associated with a variety of cellular activities
LCLEADBE_00960 1.5e-225 V ABC-2 family transporter protein
LCLEADBE_00961 2.5e-256 V ABC-2 family transporter protein
LCLEADBE_00962 1.2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
LCLEADBE_00963 8.5e-113 E GDSL-like Lipase/Acylhydrolase family
LCLEADBE_00964 1.9e-196
LCLEADBE_00965 3.6e-114 3.4.13.21 E Peptidase family S51
LCLEADBE_00966 4.3e-112 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
LCLEADBE_00967 5.1e-165 M pfam nlp p60
LCLEADBE_00968 3.9e-161 I Serine aminopeptidase, S33
LCLEADBE_00969 1.1e-40 S Protein of unknown function (DUF2975)
LCLEADBE_00970 2.8e-31 yozG K Cro/C1-type HTH DNA-binding domain
LCLEADBE_00971 1e-243 pbuX F Permease family
LCLEADBE_00972 9.7e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LCLEADBE_00973 0.0 pcrA 3.6.4.12 L DNA helicase
LCLEADBE_00974 1.4e-63 S Domain of unknown function (DUF4418)
LCLEADBE_00975 3.6e-219 V FtsX-like permease family
LCLEADBE_00976 7.9e-163 lolD V ABC transporter
LCLEADBE_00977 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LCLEADBE_00978 8e-156 S Peptidase C26
LCLEADBE_00979 2.5e-91 3.5.4.5 F cytidine deaminase activity
LCLEADBE_00980 1.8e-46 sdpI S SdpI/YhfL protein family
LCLEADBE_00981 1.2e-111 E Transglutaminase-like superfamily
LCLEADBE_00982 7.1e-67 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
LCLEADBE_00983 1.2e-48 relB L RelB antitoxin
LCLEADBE_00984 1.9e-129 pgm3 G Phosphoglycerate mutase family
LCLEADBE_00985 2.4e-55 WQ51_05790 S Bacterial protein of unknown function (DUF948)
LCLEADBE_00986 1.6e-35
LCLEADBE_00987 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LCLEADBE_00988 2.7e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LCLEADBE_00989 5.4e-196 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LCLEADBE_00990 5.3e-70 3.4.23.43 S Type IV leader peptidase family
LCLEADBE_00991 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LCLEADBE_00992 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LCLEADBE_00993 3.1e-80 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
LCLEADBE_00994 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LCLEADBE_00995 0.0 S L,D-transpeptidase catalytic domain
LCLEADBE_00996 1.5e-291 sufB O FeS assembly protein SufB
LCLEADBE_00997 1.1e-236 sufD O FeS assembly protein SufD
LCLEADBE_00998 7e-144 sufC O FeS assembly ATPase SufC
LCLEADBE_00999 2.2e-240 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LCLEADBE_01000 8.1e-102 iscU C SUF system FeS assembly protein, NifU family
LCLEADBE_01001 5e-110 yitW S Iron-sulfur cluster assembly protein
LCLEADBE_01002 6.2e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LCLEADBE_01003 3.3e-166 spoU 2.1.1.185 J SpoU rRNA Methylase family
LCLEADBE_01005 1e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LCLEADBE_01006 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
LCLEADBE_01007 3.8e-218 phoH T PhoH-like protein
LCLEADBE_01008 4.7e-102 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LCLEADBE_01009 2.3e-249 corC S CBS domain
LCLEADBE_01010 4.3e-186 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LCLEADBE_01011 0.0 fadD 6.2.1.3 I AMP-binding enzyme
LCLEADBE_01012 4.8e-205 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
LCLEADBE_01013 2.1e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
LCLEADBE_01014 1.7e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LCLEADBE_01015 4.9e-235 yhjX EGP Major facilitator Superfamily
LCLEADBE_01016 1.7e-103 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LCLEADBE_01017 1.6e-226 ilvE 2.6.1.42 E Amino-transferase class IV
LCLEADBE_01018 2.9e-146 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
LCLEADBE_01019 8.8e-139 S UPF0126 domain
LCLEADBE_01020 5.8e-34 rpsT J Binds directly to 16S ribosomal RNA
LCLEADBE_01021 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LCLEADBE_01022 5.1e-256 hemN H Involved in the biosynthesis of porphyrin-containing compound
LCLEADBE_01024 1.2e-191 K helix_turn _helix lactose operon repressor
LCLEADBE_01025 3e-24 K purine nucleotide biosynthetic process
LCLEADBE_01026 1.6e-38 K helix_turn _helix lactose operon repressor
LCLEADBE_01027 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
LCLEADBE_01028 1.4e-305 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
LCLEADBE_01029 1.3e-45
LCLEADBE_01030 0.0 E ABC transporter, substrate-binding protein, family 5
LCLEADBE_01031 0.0 S Glycosyl hydrolases related to GH101 family, GH129
LCLEADBE_01032 5.9e-82
LCLEADBE_01033 3.9e-245 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
LCLEADBE_01034 5.8e-160 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
LCLEADBE_01035 2.4e-161 S Sucrose-6F-phosphate phosphohydrolase
LCLEADBE_01037 3.4e-106 bcp 1.11.1.15 O Redoxin
LCLEADBE_01038 3.9e-145
LCLEADBE_01039 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_01040 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_01044 7.8e-137 yfbU S YfbU domain
LCLEADBE_01046 1.9e-32 rarD S EamA-like transporter family
LCLEADBE_01047 1.7e-127 S Plasmid pRiA4b ORF-3-like protein
LCLEADBE_01048 2.5e-129
LCLEADBE_01050 1.7e-181 I alpha/beta hydrolase fold
LCLEADBE_01051 5.3e-92 S Appr-1'-p processing enzyme
LCLEADBE_01052 6.5e-147 S phosphoesterase or phosphohydrolase
LCLEADBE_01053 2e-140 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LCLEADBE_01055 1.3e-133 S Phospholipase/Carboxylesterase
LCLEADBE_01056 5.4e-203 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LCLEADBE_01057 5.8e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
LCLEADBE_01059 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LCLEADBE_01060 5.7e-163 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
LCLEADBE_01061 1.7e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LCLEADBE_01062 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
LCLEADBE_01063 8.3e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LCLEADBE_01064 7e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
LCLEADBE_01065 2.3e-292 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LCLEADBE_01066 1.6e-177 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
LCLEADBE_01067 6.3e-159 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
LCLEADBE_01068 3.3e-183 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LCLEADBE_01069 5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LCLEADBE_01070 9e-29
LCLEADBE_01071 7.3e-219 MA20_36090 S Psort location Cytoplasmic, score 8.87
LCLEADBE_01072 9.4e-172 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
LCLEADBE_01073 9.4e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LCLEADBE_01074 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LCLEADBE_01075 3.7e-301 ybiT S ABC transporter
LCLEADBE_01076 1.4e-130 S Enoyl-(Acyl carrier protein) reductase
LCLEADBE_01077 9.1e-135 P ABC transporter
LCLEADBE_01078 5.8e-70 XK26_04485 P Cobalt transport protein
LCLEADBE_01079 5e-234 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
LCLEADBE_01080 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LCLEADBE_01081 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LCLEADBE_01082 6.7e-192 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
LCLEADBE_01083 2.6e-180 rapZ S Displays ATPase and GTPase activities
LCLEADBE_01084 3.5e-169 whiA K May be required for sporulation
LCLEADBE_01085 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
LCLEADBE_01086 9.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LCLEADBE_01087 2.5e-34 secG U Preprotein translocase SecG subunit
LCLEADBE_01088 1.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LCLEADBE_01089 2e-160 S Sucrose-6F-phosphate phosphohydrolase
LCLEADBE_01090 3.6e-301 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
LCLEADBE_01091 5.8e-190
LCLEADBE_01092 8.1e-241 brnQ U Component of the transport system for branched-chain amino acids
LCLEADBE_01093 3.6e-202 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LCLEADBE_01094 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
LCLEADBE_01095 9.7e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LCLEADBE_01096 1.8e-212 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LCLEADBE_01097 1.1e-157 G Fructosamine kinase
LCLEADBE_01098 1.8e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LCLEADBE_01099 2.8e-62 S PAC2 family
LCLEADBE_01100 9.8e-57 S PAC2 family
LCLEADBE_01106 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LCLEADBE_01107 3.1e-112 hit 2.7.7.53 FG HIT domain
LCLEADBE_01108 2e-111 yebC K transcriptional regulatory protein
LCLEADBE_01109 2.7e-100 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LCLEADBE_01110 3.2e-107 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LCLEADBE_01111 9.4e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LCLEADBE_01112 1.2e-52 yajC U Preprotein translocase subunit
LCLEADBE_01113 2.7e-100 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCLEADBE_01114 3.1e-223 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LCLEADBE_01115 2.9e-165 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LCLEADBE_01116 6e-236
LCLEADBE_01117 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LCLEADBE_01118 4.8e-32
LCLEADBE_01119 2.9e-120 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LCLEADBE_01120 1.2e-143 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LCLEADBE_01121 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
LCLEADBE_01123 2.7e-165 supH S Sucrose-6F-phosphate phosphohydrolase
LCLEADBE_01124 1.1e-294 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
LCLEADBE_01125 0.0 pafB K WYL domain
LCLEADBE_01126 6.1e-54
LCLEADBE_01127 0.0 helY L DEAD DEAH box helicase
LCLEADBE_01128 5.1e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
LCLEADBE_01129 5.7e-140 pgp 3.1.3.18 S HAD-hyrolase-like
LCLEADBE_01130 4.7e-37
LCLEADBE_01131 6.8e-66
LCLEADBE_01132 6.8e-113 K helix_turn_helix, mercury resistance
LCLEADBE_01133 6.7e-75 garA T Inner membrane component of T3SS, cytoplasmic domain
LCLEADBE_01134 5.9e-141 S Bacterial protein of unknown function (DUF881)
LCLEADBE_01135 3.9e-35 sbp S Protein of unknown function (DUF1290)
LCLEADBE_01136 4.1e-173 S Bacterial protein of unknown function (DUF881)
LCLEADBE_01137 4.2e-107 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LCLEADBE_01138 7.9e-157 hisG 2.4.2.17 F ATP phosphoribosyltransferase
LCLEADBE_01139 9.9e-42 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
LCLEADBE_01140 1.4e-113 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
LCLEADBE_01141 2.4e-186 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LCLEADBE_01142 8.3e-162 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LCLEADBE_01143 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LCLEADBE_01144 6.5e-133 S SOS response associated peptidase (SRAP)
LCLEADBE_01145 1.2e-160 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LCLEADBE_01146 1.6e-260 mmuP E amino acid
LCLEADBE_01147 1.4e-99 EGP Major facilitator Superfamily
LCLEADBE_01148 1.4e-192 V VanZ like family
LCLEADBE_01149 2.1e-85 K Transcriptional regulator, AbiEi antitoxin
LCLEADBE_01150 6.5e-81 S ASCH
LCLEADBE_01151 1.5e-94 MA20_25245 K FR47-like protein
LCLEADBE_01152 3.3e-100 S Acetyltransferase (GNAT) domain
LCLEADBE_01153 1.5e-50
LCLEADBE_01154 5.2e-121
LCLEADBE_01157 2e-35 2.7.13.3 T Histidine kinase
LCLEADBE_01158 5.8e-203 2.7.13.3 T Histidine kinase
LCLEADBE_01159 4.1e-127 K helix_turn_helix, Lux Regulon
LCLEADBE_01160 3e-95
LCLEADBE_01161 3.3e-145 M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LCLEADBE_01162 1.4e-124 lolD Q ATPases associated with a variety of cellular activities
LCLEADBE_01163 8.8e-187 V MacB-like periplasmic core domain
LCLEADBE_01164 3.2e-40 relB L RelB antitoxin
LCLEADBE_01165 3.8e-50 S Bacterial toxin of type II toxin-antitoxin system, YafQ
LCLEADBE_01166 8.4e-26 2.7.13.3 T Histidine kinase
LCLEADBE_01167 7.8e-97 rpoE4 K Sigma-70 region 2
LCLEADBE_01168 7.5e-19 S Psort location CytoplasmicMembrane, score
LCLEADBE_01169 8.5e-108
LCLEADBE_01170 5.8e-138
LCLEADBE_01171 4.9e-170 yfiL V ATPases associated with a variety of cellular activities
LCLEADBE_01172 6.9e-71
LCLEADBE_01173 1.4e-62
LCLEADBE_01174 8.1e-149 S EamA-like transporter family
LCLEADBE_01175 1.1e-102
LCLEADBE_01176 9.2e-130
LCLEADBE_01177 2.2e-122 V ATPases associated with a variety of cellular activities
LCLEADBE_01178 2e-109 L Transposase and inactivated derivatives IS30 family
LCLEADBE_01179 7.2e-89 L Transposase and inactivated derivatives IS30 family
LCLEADBE_01180 8.8e-119 K Bacterial regulatory proteins, luxR family
LCLEADBE_01181 2.8e-224 T Histidine kinase
LCLEADBE_01182 3.2e-251 V Efflux ABC transporter, permease protein
LCLEADBE_01183 2.3e-162 V ABC transporter
LCLEADBE_01185 7.4e-49 S Protein of unknown function (DUF2089)
LCLEADBE_01186 1.3e-52
LCLEADBE_01187 5.5e-71 K Transcriptional regulator
LCLEADBE_01188 3.2e-110
LCLEADBE_01189 3.7e-45 K sequence-specific DNA binding
LCLEADBE_01190 8.3e-34 hipA 2.7.11.1 S kinase activity
LCLEADBE_01191 4.4e-42 2.6.1.76 EGP Major Facilitator Superfamily
LCLEADBE_01192 6.3e-20 G Major facilitator Superfamily
LCLEADBE_01193 4.7e-296 mmuP E amino acid
LCLEADBE_01195 1e-62 yeaO K Protein of unknown function, DUF488
LCLEADBE_01196 5.3e-77
LCLEADBE_01197 5e-174 3.6.4.12
LCLEADBE_01198 4e-65 yijF S Domain of unknown function (DUF1287)
LCLEADBE_01199 9.9e-299 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LCLEADBE_01200 5.3e-71 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LCLEADBE_01201 6.1e-140 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LCLEADBE_01202 1.6e-70 3.5.1.124 S DJ-1/PfpI family
LCLEADBE_01203 2.7e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LCLEADBE_01204 3.7e-174 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
LCLEADBE_01205 1.5e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LCLEADBE_01206 2.8e-134 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LCLEADBE_01207 1.4e-145 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LCLEADBE_01208 5.8e-144 rpsB J Belongs to the universal ribosomal protein uS2 family
LCLEADBE_01209 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LCLEADBE_01210 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
LCLEADBE_01211 3.3e-91
LCLEADBE_01212 4e-209 guaB 1.1.1.205 F IMP dehydrogenase family protein
LCLEADBE_01213 4.6e-243 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
LCLEADBE_01214 4.1e-258 G ABC transporter substrate-binding protein
LCLEADBE_01215 2.4e-36 M Peptidase family M23
LCLEADBE_01216 3e-71 L Phage integrase family
LCLEADBE_01217 4.7e-282 L PFAM Integrase catalytic
LCLEADBE_01218 1.7e-142 L IstB-like ATP binding protein
LCLEADBE_01219 7.4e-26 L Phage integrase family
LCLEADBE_01221 1.5e-225
LCLEADBE_01222 2.6e-185 pstIR 2.1.1.72, 3.1.21.4 L BsuBI/PstI restriction endonuclease C-terminus
LCLEADBE_01223 3.3e-269 hsdBM 2.1.1.72 L Eco57I restriction-modification methylase
LCLEADBE_01224 0.0 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
LCLEADBE_01225 3.5e-207 dcm 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
LCLEADBE_01226 0.0 topB 5.99.1.2 L DNA topoisomerase
LCLEADBE_01229 6.2e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LCLEADBE_01230 1e-105 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
LCLEADBE_01231 5.5e-161 yeaZ 2.3.1.234 O Glycoprotease family
LCLEADBE_01232 4e-88 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
LCLEADBE_01233 2.4e-173 holA 2.7.7.7 L DNA polymerase III delta subunit
LCLEADBE_01234 0.0 comE S Competence protein
LCLEADBE_01235 1.5e-81 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
LCLEADBE_01236 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LCLEADBE_01237 5.5e-161 ET Bacterial periplasmic substrate-binding proteins
LCLEADBE_01238 2.4e-170 corA P CorA-like Mg2+ transporter protein
LCLEADBE_01239 5.4e-166 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
LCLEADBE_01240 1.4e-234 L ribosomal rna small subunit methyltransferase
LCLEADBE_01241 4.1e-71 pdxH S Pfam:Pyridox_oxidase
LCLEADBE_01242 7.3e-172 EG EamA-like transporter family
LCLEADBE_01243 2.1e-131 C Putative TM nitroreductase
LCLEADBE_01244 1.9e-31
LCLEADBE_01245 4.7e-262 S Metal-independent alpha-mannosidase (GH125)
LCLEADBE_01246 2.5e-252 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
LCLEADBE_01247 4.5e-208 K helix_turn _helix lactose operon repressor
LCLEADBE_01248 0.0 3.2.1.96 G Glycosyl hydrolase family 85
LCLEADBE_01249 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
LCLEADBE_01250 1.9e-263 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
LCLEADBE_01251 5.2e-156 lacG G Binding-protein-dependent transport system inner membrane component
LCLEADBE_01252 4.3e-172 malC G Binding-protein-dependent transport system inner membrane component
LCLEADBE_01253 3e-245 srrA1 G Bacterial extracellular solute-binding protein
LCLEADBE_01254 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
LCLEADBE_01255 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
LCLEADBE_01256 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
LCLEADBE_01257 8.2e-40
LCLEADBE_01258 1e-173 S Fic/DOC family
LCLEADBE_01259 1.7e-259 S HipA-like C-terminal domain
LCLEADBE_01261 2.3e-74
LCLEADBE_01262 1.6e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LCLEADBE_01263 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCLEADBE_01264 1.7e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
LCLEADBE_01265 1.4e-47 S Domain of unknown function (DUF4193)
LCLEADBE_01266 1.6e-151 S Protein of unknown function (DUF3071)
LCLEADBE_01267 1.5e-233 S Type I phosphodiesterase / nucleotide pyrophosphatase
LCLEADBE_01268 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
LCLEADBE_01270 1.8e-43 K Psort location Cytoplasmic, score
LCLEADBE_01271 1.2e-48 K Psort location Cytoplasmic, score
LCLEADBE_01272 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_01273 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_01274 0.0 lhr L DEAD DEAH box helicase
LCLEADBE_01275 3.1e-173 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCLEADBE_01276 4.5e-222 G Major Facilitator Superfamily
LCLEADBE_01277 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
LCLEADBE_01278 8.2e-191 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LCLEADBE_01279 3e-116
LCLEADBE_01280 2.9e-196 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
LCLEADBE_01281 0.0 pknL 2.7.11.1 KLT PASTA
LCLEADBE_01282 6.2e-131 plsC2 2.3.1.51 I Phosphate acyltransferases
LCLEADBE_01283 5.3e-119
LCLEADBE_01284 9.9e-194 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LCLEADBE_01285 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LCLEADBE_01286 1.3e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LCLEADBE_01287 3.5e-103 recX S Modulates RecA activity
LCLEADBE_01288 8.3e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCLEADBE_01289 7e-39 S Protein of unknown function (DUF3046)
LCLEADBE_01290 8.1e-80 K Helix-turn-helix XRE-family like proteins
LCLEADBE_01291 4.6e-97 cinA 3.5.1.42 S Belongs to the CinA family
LCLEADBE_01292 1.2e-117 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LCLEADBE_01293 0.0 ftsK D FtsK SpoIIIE family protein
LCLEADBE_01294 2.9e-152 fic D Fic/DOC family
LCLEADBE_01295 3e-184 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LCLEADBE_01296 1.8e-278 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LCLEADBE_01297 5.2e-150 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
LCLEADBE_01298 3.2e-167 ydeD EG EamA-like transporter family
LCLEADBE_01299 5.1e-137 ybhL S Belongs to the BI1 family
LCLEADBE_01300 1.5e-83 K helix_turn_helix, Lux Regulon
LCLEADBE_01301 6.8e-121 E Psort location Cytoplasmic, score 8.87
LCLEADBE_01302 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LCLEADBE_01303 0.0 ctpE P E1-E2 ATPase
LCLEADBE_01304 2e-98
LCLEADBE_01305 1.8e-242 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LCLEADBE_01306 3.8e-134 S Protein of unknown function (DUF3159)
LCLEADBE_01307 1.5e-155 S Protein of unknown function (DUF3710)
LCLEADBE_01308 3.3e-171 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
LCLEADBE_01309 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
LCLEADBE_01310 1.1e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
LCLEADBE_01311 8.9e-154 dppB EP Binding-protein-dependent transport system inner membrane component
LCLEADBE_01312 0.0 E ABC transporter, substrate-binding protein, family 5
LCLEADBE_01313 6.5e-190 xerC D Belongs to the 'phage' integrase family. XerC subfamily
LCLEADBE_01314 2.2e-148 V ABC transporter, ATP-binding protein
LCLEADBE_01315 0.0 MV MacB-like periplasmic core domain
LCLEADBE_01316 4.5e-42
LCLEADBE_01317 3.8e-190 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
LCLEADBE_01318 1.8e-189 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
LCLEADBE_01319 3.6e-79
LCLEADBE_01320 0.0 typA T Elongation factor G C-terminus
LCLEADBE_01321 5.3e-107 K Virulence activator alpha C-term
LCLEADBE_01322 4.8e-137 V ATPases associated with a variety of cellular activities
LCLEADBE_01323 0.0 V FtsX-like permease family
LCLEADBE_01324 4.5e-19 naiP U Sugar (and other) transporter
LCLEADBE_01325 4.6e-241 iscS1 2.8.1.7 E Aminotransferase class-V
LCLEADBE_01326 2e-163 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
LCLEADBE_01327 1.2e-304 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
LCLEADBE_01328 9.8e-252 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LCLEADBE_01329 3.4e-160 nrtR 3.6.1.55 F NUDIX hydrolase
LCLEADBE_01330 5.7e-118 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LCLEADBE_01331 1.7e-151 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LCLEADBE_01332 3.8e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
LCLEADBE_01333 1.3e-160 xerD D recombinase XerD
LCLEADBE_01334 2.4e-217 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LCLEADBE_01335 1.3e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LCLEADBE_01336 6.2e-25 rpmI J Ribosomal protein L35
LCLEADBE_01337 1.7e-113 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LCLEADBE_01338 3.2e-46 S Spermine/spermidine synthase domain
LCLEADBE_01339 7.7e-137 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
LCLEADBE_01340 5.7e-197 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LCLEADBE_01341 8.5e-90 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LCLEADBE_01342 7.5e-183 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LCLEADBE_01343 1.3e-192 galM 5.1.3.3 G Aldose 1-epimerase
LCLEADBE_01344 1.1e-188 galM 5.1.3.3 G Aldose 1-epimerase
LCLEADBE_01345 3.3e-52
LCLEADBE_01346 3.6e-137 sigH K Belongs to the sigma-70 factor family. ECF subfamily
LCLEADBE_01347 8.4e-298 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LCLEADBE_01348 1.1e-197 V Acetyltransferase (GNAT) domain
LCLEADBE_01349 8.9e-104 V Acetyltransferase (GNAT) domain
LCLEADBE_01350 0.0 smc D Required for chromosome condensation and partitioning
LCLEADBE_01351 8.1e-304 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
LCLEADBE_01352 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
LCLEADBE_01353 6.6e-98 3.6.1.55 F NUDIX domain
LCLEADBE_01354 3.8e-248 nagA 3.5.1.25 G Amidohydrolase family
LCLEADBE_01355 2.1e-151 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LCLEADBE_01356 3.6e-210 GK ROK family
LCLEADBE_01357 2.2e-165 2.7.1.2 GK ROK family
LCLEADBE_01358 6.1e-227 GK ROK family
LCLEADBE_01359 5.6e-169 2.7.1.4 G pfkB family carbohydrate kinase
LCLEADBE_01360 1.3e-27 G Major Facilitator Superfamily
LCLEADBE_01361 1e-75 G Major Facilitator Superfamily
LCLEADBE_01362 1.2e-88 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LCLEADBE_01363 7e-15
LCLEADBE_01364 6.6e-174 ftsQ 6.3.2.4 D Cell division protein FtsQ
LCLEADBE_01365 2.5e-286 murC 6.3.2.8 M Belongs to the MurCDEF family
LCLEADBE_01366 1.2e-219 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LCLEADBE_01367 1.5e-225 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
LCLEADBE_01368 2.3e-273 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LCLEADBE_01369 1.2e-205 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LCLEADBE_01370 1.2e-242 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LCLEADBE_01371 2e-155 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LCLEADBE_01372 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
LCLEADBE_01373 1.4e-67 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LCLEADBE_01374 3.2e-192 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LCLEADBE_01375 1.3e-93 mraZ K Belongs to the MraZ family
LCLEADBE_01376 0.0 L DNA helicase
LCLEADBE_01377 2.6e-230 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
LCLEADBE_01378 8.4e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LCLEADBE_01379 1.8e-47 M Lysin motif
LCLEADBE_01380 6.9e-130 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LCLEADBE_01381 2.8e-163 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCLEADBE_01382 1.7e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
LCLEADBE_01383 4.1e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCLEADBE_01384 1.5e-123 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
LCLEADBE_01385 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
LCLEADBE_01386 1e-218 EGP Major facilitator Superfamily
LCLEADBE_01387 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
LCLEADBE_01388 1.5e-280 S Uncharacterized protein conserved in bacteria (DUF2252)
LCLEADBE_01389 1.3e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
LCLEADBE_01390 1.4e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LCLEADBE_01391 2.3e-99
LCLEADBE_01392 2.7e-111 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
LCLEADBE_01393 1.5e-222 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCLEADBE_01394 2.7e-255 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LCLEADBE_01395 5.6e-55 acyP 3.6.1.7 C Acylphosphatase
LCLEADBE_01396 2.4e-158 yvgN 1.1.1.346 S Aldo/keto reductase family
LCLEADBE_01397 0.0 2.4.1.230, 3.2.1.51 GH65,GH95 G Glycosyl hydrolase family 65, N-terminal domain
LCLEADBE_01398 8.8e-167 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
LCLEADBE_01399 1.6e-159 S Amidohydrolase
LCLEADBE_01400 1.1e-147 IQ KR domain
LCLEADBE_01401 4.3e-132 4.2.1.68 M Enolase C-terminal domain-like
LCLEADBE_01402 9.3e-10
LCLEADBE_01403 0.0 4.2.1.53 S MCRA family
LCLEADBE_01404 1.2e-168 dkgA 1.1.1.346 C Aldo/keto reductase family
LCLEADBE_01405 1.5e-39 yneG S Domain of unknown function (DUF4186)
LCLEADBE_01406 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
LCLEADBE_01407 2.6e-202 K WYL domain
LCLEADBE_01408 9e-178 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LCLEADBE_01409 5.4e-90 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LCLEADBE_01410 5.3e-22 tccB2 V DivIVA protein
LCLEADBE_01411 4.9e-45 yggT S YGGT family
LCLEADBE_01412 3.4e-72 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LCLEADBE_01413 1.2e-211 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LCLEADBE_01414 5.7e-249 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LCLEADBE_01415 3e-297 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
LCLEADBE_01416 2.8e-123
LCLEADBE_01417 1.3e-139 cbiO V ATPases associated with a variety of cellular activities
LCLEADBE_01418 3.1e-105
LCLEADBE_01419 5.3e-68 marR5 K Winged helix DNA-binding domain
LCLEADBE_01420 2.8e-96
LCLEADBE_01421 4.5e-169 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LCLEADBE_01422 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LCLEADBE_01423 1.8e-231 O AAA domain (Cdc48 subfamily)
LCLEADBE_01424 4.6e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LCLEADBE_01425 5.6e-62 S Thiamine-binding protein
LCLEADBE_01426 7.1e-248 ydjK G Sugar (and other) transporter
LCLEADBE_01427 1.9e-216 2.7.13.3 T Histidine kinase
LCLEADBE_01428 6.1e-123 K helix_turn_helix, Lux Regulon
LCLEADBE_01429 4.5e-191
LCLEADBE_01430 2.6e-261 O SERine Proteinase INhibitors
LCLEADBE_01431 1.8e-195 K helix_turn _helix lactose operon repressor
LCLEADBE_01432 1.5e-97 M1-431 S Protein of unknown function (DUF1706)
LCLEADBE_01433 9.3e-83 lacY P LacY proton/sugar symporter
LCLEADBE_01434 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
LCLEADBE_01435 3.2e-141 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
LCLEADBE_01436 2.5e-149 C Putative TM nitroreductase
LCLEADBE_01437 6.4e-198 S Glycosyltransferase, group 2 family protein
LCLEADBE_01438 1.3e-93 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LCLEADBE_01439 0.0 ecfA GP ABC transporter, ATP-binding protein
LCLEADBE_01440 3.1e-47 yhbY J CRS1_YhbY
LCLEADBE_01441 1.4e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
LCLEADBE_01442 5.3e-52
LCLEADBE_01443 6.9e-189 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
LCLEADBE_01444 4.1e-254 EGP Major facilitator Superfamily
LCLEADBE_01445 2.3e-33 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LCLEADBE_01446 6.9e-11 KT Transcriptional regulatory protein, C terminal
LCLEADBE_01447 4.7e-252 rarA L Recombination factor protein RarA
LCLEADBE_01448 0.0 helY L DEAD DEAH box helicase
LCLEADBE_01449 2.8e-199 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
LCLEADBE_01451 5.7e-288 ydfD EK Alanine-glyoxylate amino-transferase
LCLEADBE_01452 1.3e-111 argO S LysE type translocator
LCLEADBE_01453 1.1e-292 phoN I PAP2 superfamily
LCLEADBE_01454 1.7e-204 gluD E Binding-protein-dependent transport system inner membrane component
LCLEADBE_01455 1.2e-110 gluC E Binding-protein-dependent transport system inner membrane component
LCLEADBE_01456 5.3e-147 gluB ET Belongs to the bacterial solute-binding protein 3 family
LCLEADBE_01457 3.1e-153 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
LCLEADBE_01458 6.1e-102 S Aminoacyl-tRNA editing domain
LCLEADBE_01459 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LCLEADBE_01460 5.9e-261 hisS 6.1.1.21 J Histidyl-tRNA synthetase
LCLEADBE_01461 2e-224 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
LCLEADBE_01462 0.0 3.1.3.5 F 5'-nucleotidase, C-terminal domain
LCLEADBE_01463 3.4e-143 3.5.2.10 S Creatinine amidohydrolase
LCLEADBE_01464 8e-252 proP EGP Sugar (and other) transporter
LCLEADBE_01466 1.7e-279 purR QT Purine catabolism regulatory protein-like family
LCLEADBE_01467 8e-257 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
LCLEADBE_01468 0.0 clpC O ATPase family associated with various cellular activities (AAA)
LCLEADBE_01469 1.4e-178 uspA T Belongs to the universal stress protein A family
LCLEADBE_01470 3.7e-180 S Protein of unknown function (DUF3027)
LCLEADBE_01471 1.7e-66 cspB K 'Cold-shock' DNA-binding domain
LCLEADBE_01472 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
LCLEADBE_01473 2e-132 KT Response regulator receiver domain protein
LCLEADBE_01474 1.3e-100
LCLEADBE_01475 4.5e-35 S Proteins of 100 residues with WXG
LCLEADBE_01476 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LCLEADBE_01477 6.1e-38 K 'Cold-shock' DNA-binding domain
LCLEADBE_01478 8.1e-85 S LytR cell envelope-related transcriptional attenuator
LCLEADBE_01479 5.8e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LCLEADBE_01480 1.7e-188 moxR S ATPase family associated with various cellular activities (AAA)
LCLEADBE_01481 3.3e-164 S Protein of unknown function DUF58
LCLEADBE_01482 4.6e-86
LCLEADBE_01483 6.7e-190 S von Willebrand factor (vWF) type A domain
LCLEADBE_01484 1e-153 S von Willebrand factor (vWF) type A domain
LCLEADBE_01485 1.1e-56
LCLEADBE_01486 1.9e-257 S PGAP1-like protein
LCLEADBE_01487 1e-111 ykoE S ABC-type cobalt transport system, permease component
LCLEADBE_01488 2.3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
LCLEADBE_01489 0.0 S Lysylphosphatidylglycerol synthase TM region
LCLEADBE_01490 8.1e-42 hup L Belongs to the bacterial histone-like protein family
LCLEADBE_01491 1.9e-286 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LCLEADBE_01493 8.9e-175 hisN 3.1.3.25 G Inositol monophosphatase family
LCLEADBE_01494 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
LCLEADBE_01495 8.4e-136 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
LCLEADBE_01496 1.7e-162 G Phosphotransferase System
LCLEADBE_01497 2.1e-46 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
LCLEADBE_01498 1.1e-78 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LCLEADBE_01499 3e-72 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LCLEADBE_01500 2.6e-280 manR K PRD domain
LCLEADBE_01501 7.6e-137 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LCLEADBE_01502 2.1e-288 arc O AAA ATPase forming ring-shaped complexes
LCLEADBE_01503 2.2e-125 apl 3.1.3.1 S SNARE associated Golgi protein
LCLEADBE_01504 2.3e-120 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
LCLEADBE_01505 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCLEADBE_01506 4.6e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LCLEADBE_01507 4.5e-191 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LCLEADBE_01508 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
LCLEADBE_01509 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LCLEADBE_01510 1.3e-229 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LCLEADBE_01511 1.7e-139 L IstB-like ATP binding protein
LCLEADBE_01512 5.6e-32 L PFAM Integrase catalytic
LCLEADBE_01513 5.8e-296 L PFAM Integrase catalytic
LCLEADBE_01514 4.1e-144 L IstB-like ATP binding protein
LCLEADBE_01515 7.6e-233 L PFAM Integrase catalytic
LCLEADBE_01516 5.3e-07 S Bacterial toxin of type II toxin-antitoxin system, YafQ
LCLEADBE_01518 1.8e-36 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LCLEADBE_01519 1.3e-198 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LCLEADBE_01520 7.1e-132 cas4 3.1.12.1 L Domain of unknown function DUF83
LCLEADBE_01521 3.5e-157 csd2 L CRISPR-associated protein Cas7
LCLEADBE_01522 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
LCLEADBE_01523 1.5e-137 cas5d S CRISPR-associated protein (Cas_Cas5)
LCLEADBE_01524 0.0 cas3 L DEAD-like helicases superfamily
LCLEADBE_01525 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_01526 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_01527 1.1e-31 L Transposase
LCLEADBE_01528 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LCLEADBE_01529 3.1e-168 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCLEADBE_01530 1.9e-68 rbsD 5.4.99.62 G RbsD / FucU transport protein family
LCLEADBE_01531 1.8e-162 rbsB G Periplasmic binding protein domain
LCLEADBE_01532 4.9e-158 rbsC U Branched-chain amino acid transport system / permease component
LCLEADBE_01533 2.5e-278 rbsA 3.6.3.17 G ATPases associated with a variety of cellular activities
LCLEADBE_01534 2.6e-186 rbsR K helix_turn _helix lactose operon repressor
LCLEADBE_01535 1.2e-36 L Transposase
LCLEADBE_01536 2.6e-261 EGP Major Facilitator Superfamily
LCLEADBE_01537 4e-167 rbsK 2.7.1.15 G Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCLEADBE_01538 7.6e-230 bdhA C Iron-containing alcohol dehydrogenase
LCLEADBE_01539 7.1e-132 3.1.3.18 S Haloacid dehalogenase-like hydrolase
LCLEADBE_01540 7.4e-191 rihB 3.2.2.1, 3.2.2.8 F Inosine-uridine preferring nucleoside hydrolase
LCLEADBE_01541 2.6e-180 ydjH 2.7.1.15 G pfkB family carbohydrate kinase
LCLEADBE_01542 1.4e-118 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
LCLEADBE_01543 7.1e-155 P ATPases associated with a variety of cellular activities
LCLEADBE_01544 1.8e-153 P ATPases associated with a variety of cellular activities
LCLEADBE_01545 2.2e-140 cbiQ P Cobalt transport protein
LCLEADBE_01546 1.8e-100 2.7.7.65 T ECF transporter, substrate-specific component
LCLEADBE_01547 0.0 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCLEADBE_01548 0.0 V ABC transporter transmembrane region
LCLEADBE_01549 0.0 V ABC transporter, ATP-binding protein
LCLEADBE_01550 7.3e-92 K MarR family
LCLEADBE_01551 1.5e-189 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
LCLEADBE_01552 2.7e-243 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
LCLEADBE_01553 2.6e-70 S Nucleotidyltransferase substrate binding protein like
LCLEADBE_01554 3.3e-46 S Nucleotidyltransferase domain
LCLEADBE_01556 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
LCLEADBE_01557 2.1e-142 K Bacterial regulatory proteins, tetR family
LCLEADBE_01558 5e-256 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
LCLEADBE_01559 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
LCLEADBE_01560 3.8e-144 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCLEADBE_01561 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
LCLEADBE_01562 4.8e-257 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LCLEADBE_01563 3.7e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LCLEADBE_01564 4.1e-95 ywrO 1.6.5.2 S Flavodoxin-like fold
LCLEADBE_01565 0.0 fadD 6.2.1.3 I AMP-binding enzyme
LCLEADBE_01566 3.2e-65 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LCLEADBE_01567 3.7e-78 F Nucleoside 2-deoxyribosyltransferase
LCLEADBE_01569 6.3e-202 S Endonuclease/Exonuclease/phosphatase family
LCLEADBE_01570 1.5e-180 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
LCLEADBE_01571 6e-235 aspB E Aminotransferase class-V
LCLEADBE_01572 5.9e-202 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
LCLEADBE_01573 7.9e-90 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
LCLEADBE_01574 4.1e-101 XK27_03610 K Acetyltransferase (GNAT) domain
LCLEADBE_01575 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
LCLEADBE_01576 4e-147 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
LCLEADBE_01577 2.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
LCLEADBE_01578 9.2e-152 map 3.4.11.18 E Methionine aminopeptidase
LCLEADBE_01579 4.7e-144 S Short repeat of unknown function (DUF308)
LCLEADBE_01580 0.0 pepO 3.4.24.71 O Peptidase family M13
LCLEADBE_01581 5.7e-118 L Single-strand binding protein family
LCLEADBE_01582 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LCLEADBE_01583 3.4e-155 pflA 1.97.1.4 O Radical SAM superfamily
LCLEADBE_01584 4.4e-269 recD2 3.6.4.12 L PIF1-like helicase
LCLEADBE_01585 4.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
LCLEADBE_01586 4.3e-294 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LCLEADBE_01587 3e-213 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
LCLEADBE_01588 1.5e-118 ywlC 2.7.7.87 J Belongs to the SUA5 family
LCLEADBE_01589 6.6e-125 livF E ATPases associated with a variety of cellular activities
LCLEADBE_01590 6.3e-162 E Branched-chain amino acid ATP-binding cassette transporter
LCLEADBE_01591 4.5e-189 livM U Belongs to the binding-protein-dependent transport system permease family
LCLEADBE_01592 5.4e-111 U Belongs to the binding-protein-dependent transport system permease family
LCLEADBE_01593 1.8e-207 livK E Receptor family ligand binding region
LCLEADBE_01594 8.2e-165 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LCLEADBE_01595 3.7e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LCLEADBE_01596 1.3e-36 rpmE J Binds the 23S rRNA
LCLEADBE_01598 4.4e-101 yebQ EGP Major facilitator Superfamily
LCLEADBE_01599 7.6e-154
LCLEADBE_01600 3.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LCLEADBE_01601 1.4e-166 dkgB S Oxidoreductase, aldo keto reductase family protein
LCLEADBE_01602 1.5e-18 lmrB U Major Facilitator Superfamily
LCLEADBE_01603 4.8e-88 K Winged helix DNA-binding domain
LCLEADBE_01604 5.3e-178 glkA 2.7.1.2 G ROK family
LCLEADBE_01606 1.5e-309 EGP Major Facilitator Superfamily
LCLEADBE_01607 0.0 yjjK S ATP-binding cassette protein, ChvD family
LCLEADBE_01608 8.7e-170 tesB I Thioesterase-like superfamily
LCLEADBE_01609 1.1e-92 S Protein of unknown function (DUF3180)
LCLEADBE_01610 3.6e-304 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LCLEADBE_01611 4.4e-163 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LCLEADBE_01612 8.6e-119 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
LCLEADBE_01613 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCLEADBE_01614 2.7e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LCLEADBE_01615 1.5e-211 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LCLEADBE_01616 1.6e-253 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
LCLEADBE_01617 6.7e-301
LCLEADBE_01618 1.6e-191 natA V ATPases associated with a variety of cellular activities
LCLEADBE_01619 1.6e-235 epsG M Glycosyl transferase family 21
LCLEADBE_01620 1e-282 S AI-2E family transporter
LCLEADBE_01621 5.5e-180 3.4.14.13 M Glycosyltransferase like family 2
LCLEADBE_01622 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
LCLEADBE_01623 4.3e-263 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
LCLEADBE_01626 1.3e-163 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LCLEADBE_01629 5.6e-10 S Helix-turn-helix domain
LCLEADBE_01630 1.1e-218 S Helix-turn-helix domain
LCLEADBE_01631 2.6e-84 S Transcription factor WhiB
LCLEADBE_01632 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_01633 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_01634 1.1e-104 parA D AAA domain
LCLEADBE_01635 6.8e-40
LCLEADBE_01636 1.3e-282 S ATPases associated with a variety of cellular activities
LCLEADBE_01637 3.4e-94 K FR47-like protein
LCLEADBE_01638 1.3e-119 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
LCLEADBE_01639 0.0 XK27_00515 D Cell surface antigen C-terminus
LCLEADBE_01640 1.5e-133 bltR K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LCLEADBE_01641 7e-197 pacB 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LCLEADBE_01642 6.9e-90
LCLEADBE_01644 1.3e-67 S Helix-turn-helix domain
LCLEADBE_01645 3.6e-105 S PIN domain
LCLEADBE_01646 1.6e-246
LCLEADBE_01647 2e-252 L Transposase, Mutator family
LCLEADBE_01648 8e-39
LCLEADBE_01649 1.1e-147
LCLEADBE_01651 4.6e-199 isp2 3.2.1.96 M CHAP domain
LCLEADBE_01652 3.8e-187
LCLEADBE_01653 2.6e-191 dprA LU DNA recombination-mediator protein A
LCLEADBE_01654 1.3e-159 S competence protein
LCLEADBE_01655 0.0 3.6.4.12 L UvrD/REP helicase N-terminal domain
LCLEADBE_01656 5.6e-297 L AAA ATPase domain
LCLEADBE_01657 0.0 U Type IV secretory system Conjugative DNA transfer
LCLEADBE_01659 1.1e-53
LCLEADBE_01660 2.8e-226 ard S Antirestriction protein (ArdA)
LCLEADBE_01662 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_01663 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_01664 5.6e-116
LCLEADBE_01665 3.4e-155 S Protein of unknown function (DUF3801)
LCLEADBE_01666 3.3e-264 rlx U Relaxase/Mobilisation nuclease domain
LCLEADBE_01667 5.9e-70 S Bacterial mobilisation protein (MobC)
LCLEADBE_01668 5.4e-62
LCLEADBE_01669 4.7e-41
LCLEADBE_01670 9.2e-252 K ParB-like nuclease domain
LCLEADBE_01671 4.4e-109 S Domain of unknown function (DUF4192)
LCLEADBE_01672 6.7e-267 L Phage integrase family
LCLEADBE_01673 1.2e-15 L Phage integrase family
LCLEADBE_01674 1.5e-12 sprF 4.6.1.1 M Cell surface antigen C-terminus
LCLEADBE_01675 1.3e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
LCLEADBE_01676 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
LCLEADBE_01677 4.8e-185 lacR K Transcriptional regulator, LacI family
LCLEADBE_01678 1.4e-21 L Helix-turn-helix domain
LCLEADBE_01679 3.2e-258 G Bacterial extracellular solute-binding protein
LCLEADBE_01680 1.3e-221 GK ROK family
LCLEADBE_01681 0.0 G Glycosyl hydrolase family 20, domain 2
LCLEADBE_01682 2.8e-220 vex3 V ABC transporter permease
LCLEADBE_01683 2.5e-212 vex1 V Efflux ABC transporter, permease protein
LCLEADBE_01684 3.7e-111 vex2 V ABC transporter, ATP-binding protein
LCLEADBE_01685 1.4e-11 azlC E AzlC protein
LCLEADBE_01686 1.5e-97 ptpA 3.1.3.48 T low molecular weight
LCLEADBE_01687 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
LCLEADBE_01688 1e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LCLEADBE_01689 3.4e-73 attW O OsmC-like protein
LCLEADBE_01690 1.5e-189 T Universal stress protein family
LCLEADBE_01691 3e-104 M NlpC/P60 family
LCLEADBE_01692 1.1e-101 M NlpC/P60 family
LCLEADBE_01693 3.5e-169 usp 3.5.1.28 CBM50 S CHAP domain
LCLEADBE_01694 5e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LCLEADBE_01695 1.8e-32
LCLEADBE_01696 9.2e-175 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
LCLEADBE_01697 5.4e-116 phoU P Plays a role in the regulation of phosphate uptake
LCLEADBE_01698 1.1e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LCLEADBE_01699 1.1e-175 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
LCLEADBE_01700 2.3e-311 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LCLEADBE_01702 1.3e-218 araJ EGP Major facilitator Superfamily
LCLEADBE_01703 0.0 S Domain of unknown function (DUF4037)
LCLEADBE_01704 1.6e-117 S Protein of unknown function (DUF4125)
LCLEADBE_01705 0.0 S alpha beta
LCLEADBE_01706 4.4e-68
LCLEADBE_01707 7.4e-292 pspC KT PspC domain
LCLEADBE_01708 2.1e-238 tcsS3 KT PspC domain
LCLEADBE_01709 4.4e-118 degU K helix_turn_helix, Lux Regulon
LCLEADBE_01710 4.1e-168 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LCLEADBE_01711 8.9e-206 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
LCLEADBE_01712 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
LCLEADBE_01713 2.5e-167 G ABC transporter permease
LCLEADBE_01714 6.9e-173 malC G Binding-protein-dependent transport system inner membrane component
LCLEADBE_01715 2.5e-250 G Bacterial extracellular solute-binding protein
LCLEADBE_01717 1.1e-242 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LCLEADBE_01718 6.1e-208 I Diacylglycerol kinase catalytic domain
LCLEADBE_01719 5.9e-163 arbG K CAT RNA binding domain
LCLEADBE_01720 0.0 crr 2.7.1.193 G pts system, glucose-specific IIABC component
LCLEADBE_01721 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
LCLEADBE_01722 3.6e-199 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
LCLEADBE_01723 1.9e-74 K Transcriptional regulator
LCLEADBE_01724 5e-279 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCLEADBE_01725 9.2e-174 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCLEADBE_01726 9.1e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LCLEADBE_01728 1.6e-98
LCLEADBE_01729 5e-263 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LCLEADBE_01730 4.3e-219 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
LCLEADBE_01731 3e-223 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LCLEADBE_01732 1.6e-82 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LCLEADBE_01733 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LCLEADBE_01734 5.1e-190 nusA K Participates in both transcription termination and antitermination
LCLEADBE_01735 2.1e-126
LCLEADBE_01736 8.3e-100 K helix_turn _helix lactose operon repressor
LCLEADBE_01738 3.2e-152 E Transglutaminase/protease-like homologues
LCLEADBE_01739 0.0 gcs2 S A circularly permuted ATPgrasp
LCLEADBE_01740 8.7e-170 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LCLEADBE_01741 1.6e-62 rplQ J Ribosomal protein L17
LCLEADBE_01742 3.4e-183 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCLEADBE_01743 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LCLEADBE_01744 9.5e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LCLEADBE_01745 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LCLEADBE_01746 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LCLEADBE_01747 2.2e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LCLEADBE_01748 6.9e-248 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LCLEADBE_01749 8.1e-76 rplO J binds to the 23S rRNA
LCLEADBE_01750 7e-26 rpmD J Ribosomal protein L30p/L7e
LCLEADBE_01751 6.7e-96 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LCLEADBE_01752 2.4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LCLEADBE_01753 5.4e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LCLEADBE_01754 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LCLEADBE_01755 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LCLEADBE_01756 4.4e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LCLEADBE_01757 1.3e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LCLEADBE_01758 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LCLEADBE_01759 6.4e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LCLEADBE_01760 4.1e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
LCLEADBE_01761 2.2e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LCLEADBE_01762 1.7e-100 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LCLEADBE_01763 5.7e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LCLEADBE_01764 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LCLEADBE_01765 1.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LCLEADBE_01766 7.5e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LCLEADBE_01767 3.1e-116 rplD J Forms part of the polypeptide exit tunnel
LCLEADBE_01768 8.7e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LCLEADBE_01769 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
LCLEADBE_01770 1.2e-134 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
LCLEADBE_01771 7.8e-147 ywiC S YwiC-like protein
LCLEADBE_01772 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LCLEADBE_01773 3.5e-224 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
LCLEADBE_01774 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
LCLEADBE_01775 1.5e-07 L Transposase and inactivated derivatives IS30 family
LCLEADBE_01776 3.7e-82 rpsI J Belongs to the universal ribosomal protein uS9 family
LCLEADBE_01777 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LCLEADBE_01778 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
LCLEADBE_01779 8.4e-117
LCLEADBE_01780 3.4e-112 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
LCLEADBE_01781 2.8e-185 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCLEADBE_01782 1.1e-92 M Bacterial capsule synthesis protein PGA_cap
LCLEADBE_01783 6.3e-245 bglA 3.2.1.21 G Glycosyl hydrolase family 1
LCLEADBE_01784 6.1e-160 U Binding-protein-dependent transport system inner membrane component
LCLEADBE_01785 5.5e-164 malC U Binding-protein-dependent transport system inner membrane component
LCLEADBE_01786 1.3e-243 malE G Bacterial extracellular solute-binding protein
LCLEADBE_01787 1.4e-217 rbsR K helix_turn _helix lactose operon repressor
LCLEADBE_01788 5.2e-22
LCLEADBE_01790 9.1e-64 S EamA-like transporter family
LCLEADBE_01791 1e-21 S EamA-like transporter family
LCLEADBE_01792 1.6e-238 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCLEADBE_01793 6.1e-224 dapC E Aminotransferase class I and II
LCLEADBE_01794 2.9e-59 fdxA C 4Fe-4S binding domain
LCLEADBE_01795 1.2e-269 E aromatic amino acid transport protein AroP K03293
LCLEADBE_01796 3.8e-221 murB 1.3.1.98 M Cell wall formation
LCLEADBE_01797 4.1e-25 rpmG J Ribosomal protein L33
LCLEADBE_01801 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LCLEADBE_01802 1.1e-135
LCLEADBE_01803 2.6e-85 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
LCLEADBE_01804 1.2e-43 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
LCLEADBE_01805 4.3e-31 fmdB S Putative regulatory protein
LCLEADBE_01806 3.6e-106 flgA NO SAF
LCLEADBE_01807 3.3e-18 L Superfamily I DNA and RNA helicases and helicase subunits
LCLEADBE_01808 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
LCLEADBE_01809 1.1e-192 T Forkhead associated domain
LCLEADBE_01810 9.3e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LCLEADBE_01811 2.4e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LCLEADBE_01812 4e-147 3.2.1.8 S alpha beta
LCLEADBE_01813 1.1e-251 pbuO S Permease family
LCLEADBE_01814 1.2e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LCLEADBE_01815 1.3e-171 pstA P Phosphate transport system permease
LCLEADBE_01816 1.2e-156 pstC P probably responsible for the translocation of the substrate across the membrane
LCLEADBE_01817 1.3e-202 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
LCLEADBE_01818 3.8e-142 KT Transcriptional regulatory protein, C terminal
LCLEADBE_01819 7.2e-210 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
LCLEADBE_01820 2.1e-241 EGP Sugar (and other) transporter
LCLEADBE_01821 5.7e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LCLEADBE_01822 6.5e-237 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LCLEADBE_01823 1.3e-218 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LCLEADBE_01824 2.2e-87 ebgC G YhcH YjgK YiaL family protein
LCLEADBE_01825 0.0 ebgA 3.2.1.23 G Psort location Cytoplasmic, score 8.87
LCLEADBE_01826 1e-116 pgmB 5.4.2.6 S phosphonoacetaldehyde hydrolase activity
LCLEADBE_01827 3.2e-156 EG EamA-like transporter family
LCLEADBE_01828 0.0 kojP 2.4.1.230 GH65 G Glycosyl hydrolase family 65 central catalytic domain
LCLEADBE_01829 1.9e-152 P Binding-protein-dependent transport system inner membrane component
LCLEADBE_01830 5.3e-170 malC U Binding-protein-dependent transport system inner membrane component
LCLEADBE_01831 1.8e-237 G Bacterial extracellular solute-binding protein
LCLEADBE_01832 4.6e-188 K Periplasmic binding protein domain
LCLEADBE_01833 2.7e-100 U MarC family integral membrane protein
LCLEADBE_01834 1.3e-267 pepC 3.4.22.40 E Peptidase C1-like family
LCLEADBE_01835 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
LCLEADBE_01836 3.6e-45 D nuclear chromosome segregation
LCLEADBE_01837 2.6e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LCLEADBE_01838 8.4e-151 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LCLEADBE_01839 4.2e-200 yfiH Q Multi-copper polyphenol oxidoreductase laccase
LCLEADBE_01840 5.9e-304 yegQ O Peptidase family U32 C-terminal domain
LCLEADBE_01841 7.4e-180 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LCLEADBE_01842 7.7e-103 rsmD 2.1.1.171 L Conserved hypothetical protein 95
LCLEADBE_01843 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
LCLEADBE_01844 2.5e-29 rpmB J Ribosomal L28 family
LCLEADBE_01845 3.2e-197 yegV G pfkB family carbohydrate kinase
LCLEADBE_01846 3.9e-240 yxiO S Vacuole effluxer Atg22 like
LCLEADBE_01847 7.4e-83 soxR K helix_turn_helix, mercury resistance
LCLEADBE_01848 7.4e-64 T Toxic component of a toxin-antitoxin (TA) module
LCLEADBE_01849 8.1e-54 relB L RelB antitoxin
LCLEADBE_01850 3.6e-22 yxiO G Major facilitator Superfamily
LCLEADBE_01851 5e-193 K Helix-turn-helix XRE-family like proteins
LCLEADBE_01852 1e-116 S Alpha/beta hydrolase family
LCLEADBE_01856 4.7e-16 EGP Major facilitator Superfamily
LCLEADBE_01857 9.5e-46 XK27_04590 S NADPH-dependent FMN reductase
LCLEADBE_01859 1.5e-302 pccB I Carboxyl transferase domain
LCLEADBE_01860 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
LCLEADBE_01861 7.4e-93 bioY S BioY family
LCLEADBE_01862 4.4e-166 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
LCLEADBE_01863 0.0
LCLEADBE_01864 2.2e-165 QT PucR C-terminal helix-turn-helix domain
LCLEADBE_01865 2.7e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LCLEADBE_01866 1e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LCLEADBE_01867 2.5e-146 K Psort location Cytoplasmic, score
LCLEADBE_01868 1.4e-110 nusG K Participates in transcription elongation, termination and antitermination
LCLEADBE_01869 5.6e-33 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LCLEADBE_01871 1.5e-230 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
LCLEADBE_01872 2.7e-222 G polysaccharide deacetylase
LCLEADBE_01873 8.3e-199 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LCLEADBE_01874 0.0 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LCLEADBE_01875 5.8e-39 rpmA J Ribosomal L27 protein
LCLEADBE_01876 1.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
LCLEADBE_01877 0.0 rne 3.1.26.12 J Ribonuclease E/G family
LCLEADBE_01878 2.5e-233 dapE 3.5.1.18 E Peptidase dimerisation domain
LCLEADBE_01879 1.9e-167 mdcF S Transporter, auxin efflux carrier (AEC) family protein
LCLEADBE_01880 5.7e-166 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
LCLEADBE_01881 3.2e-149 S Amidohydrolase
LCLEADBE_01882 5.4e-202 fucP G Major Facilitator Superfamily
LCLEADBE_01883 2.8e-148 IQ KR domain
LCLEADBE_01884 1.1e-250 4.2.1.68 M Enolase C-terminal domain-like
LCLEADBE_01885 4.1e-192 K Bacterial regulatory proteins, lacI family
LCLEADBE_01886 3.7e-255 V Efflux ABC transporter, permease protein
LCLEADBE_01887 5.2e-139 V ATPases associated with a variety of cellular activities
LCLEADBE_01888 1.6e-28 S Protein of unknown function (DUF1778)
LCLEADBE_01889 2e-91 K Acetyltransferase (GNAT) family
LCLEADBE_01890 9.3e-283 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
LCLEADBE_01891 1.7e-207 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LCLEADBE_01892 2.8e-238 hom 1.1.1.3 E Homoserine dehydrogenase
LCLEADBE_01893 5.6e-54 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
LCLEADBE_01894 6.7e-55 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LCLEADBE_01895 3e-306 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LCLEADBE_01896 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LCLEADBE_01897 1.1e-132 K Bacterial regulatory proteins, tetR family
LCLEADBE_01898 7.2e-223 G Transmembrane secretion effector
LCLEADBE_01899 6.8e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCLEADBE_01900 5.3e-256 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
LCLEADBE_01901 2.1e-157 ET Bacterial periplasmic substrate-binding proteins
LCLEADBE_01902 3.7e-120 ytmL P Binding-protein-dependent transport system inner membrane component
LCLEADBE_01903 3.6e-140 P Binding-protein-dependent transport system inner membrane component
LCLEADBE_01904 3.5e-105 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
LCLEADBE_01905 9.1e-133 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
LCLEADBE_01906 1.8e-220 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
LCLEADBE_01907 2.2e-21 2.7.13.3 T Histidine kinase
LCLEADBE_01908 2e-15 S Bacterial PH domain
LCLEADBE_01909 1.4e-132 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LCLEADBE_01910 1.3e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LCLEADBE_01911 6.8e-142 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
LCLEADBE_01912 1.4e-264 S Calcineurin-like phosphoesterase
LCLEADBE_01913 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LCLEADBE_01914 2.4e-235 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
LCLEADBE_01915 8.5e-132
LCLEADBE_01916 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_01917 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_01918 0.0 G N-terminal domain of (some) glycogen debranching enzymes
LCLEADBE_01919 1.6e-49 P Binding-protein-dependent transport system inner membrane component
LCLEADBE_01920 3.9e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LCLEADBE_01921 2.8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LCLEADBE_01922 2.6e-216 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
LCLEADBE_01923 9.4e-219 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
LCLEADBE_01925 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LCLEADBE_01926 1.2e-166 S Auxin Efflux Carrier
LCLEADBE_01927 8.1e-159 fahA Q Fumarylacetoacetate (FAA) hydrolase family
LCLEADBE_01928 1.5e-119 S Domain of unknown function (DUF4190)
LCLEADBE_01929 5e-165
LCLEADBE_01930 1.1e-238 glf 5.4.99.9 M UDP-galactopyranose mutase
LCLEADBE_01931 4.8e-204 M Glycosyltransferase like family 2
LCLEADBE_01932 7.2e-245 S Predicted membrane protein (DUF2142)
LCLEADBE_01933 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
LCLEADBE_01934 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
LCLEADBE_01935 2.2e-287 lsgC M transferase activity, transferring glycosyl groups
LCLEADBE_01936 1.3e-235 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
LCLEADBE_01937 7.4e-144 rgpC U Transport permease protein
LCLEADBE_01938 0.0 rgpF M Rhamnan synthesis protein F
LCLEADBE_01939 5.6e-186 M Glycosyltransferase like family 2
LCLEADBE_01940 4.5e-171 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LCLEADBE_01941 4.6e-290 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LCLEADBE_01942 5.9e-207 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LCLEADBE_01943 0.0
LCLEADBE_01944 1.1e-175 rfbJ M Glycosyl transferase family 2
LCLEADBE_01945 1.1e-211 lytC 3.1.4.46, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
LCLEADBE_01946 3.6e-231 K Cell envelope-related transcriptional attenuator domain
LCLEADBE_01947 9.7e-264 V ABC transporter permease
LCLEADBE_01948 3.7e-189 V ABC transporter
LCLEADBE_01949 2.5e-146 T HD domain
LCLEADBE_01950 2.9e-162 S Glutamine amidotransferase domain
LCLEADBE_01951 0.0 kup P Transport of potassium into the cell
LCLEADBE_01952 8.3e-187 tatD L TatD related DNase
LCLEADBE_01953 0.0 yknV V ABC transporter
LCLEADBE_01954 0.0 mdlA2 V ABC transporter
LCLEADBE_01955 2.3e-23 S ATPase domain predominantly from Archaea
LCLEADBE_01956 1.7e-254 S Domain of unknown function (DUF4143)
LCLEADBE_01957 1e-43 G Glycosyl hydrolases family 43
LCLEADBE_01958 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
LCLEADBE_01959 0.0 oppD P Belongs to the ABC transporter superfamily
LCLEADBE_01960 3.2e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
LCLEADBE_01961 1e-176 appB EP Binding-protein-dependent transport system inner membrane component
LCLEADBE_01962 9e-281 pepC 3.4.22.40 E Peptidase C1-like family
LCLEADBE_01963 1e-47
LCLEADBE_01964 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCLEADBE_01965 9.4e-121
LCLEADBE_01966 4.8e-185 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LCLEADBE_01968 2.3e-257 G MFS/sugar transport protein
LCLEADBE_01969 2.3e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LCLEADBE_01970 0.0 lmrA2 V ABC transporter transmembrane region
LCLEADBE_01971 0.0 lmrA1 V ABC transporter, ATP-binding protein
LCLEADBE_01972 1.1e-92 ydgJ K helix_turn_helix multiple antibiotic resistance protein
LCLEADBE_01973 6.5e-09 ydcK 5.4.2.9 JM Carbohydrate binding module (family 6)
LCLEADBE_01974 9.8e-10 ydcK 3.2.1.23, 5.4.2.9 JM Carbohydrate binding module (family 6)
LCLEADBE_01975 2.1e-29 L Transposase
LCLEADBE_01976 1.4e-28 L Transposase
LCLEADBE_01977 1.8e-42 L Transposase
LCLEADBE_01978 1.5e-69 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
LCLEADBE_01979 7.3e-13 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
LCLEADBE_01980 2.6e-197 K helix_turn _helix lactose operon repressor
LCLEADBE_01981 1.4e-144
LCLEADBE_01982 0.0 3.2.1.23 G Glycosyl hydrolases family 35
LCLEADBE_01983 2.7e-134 3.6.3.17 U Branched-chain amino acid transport system / permease component
LCLEADBE_01984 1e-290 3.6.3.17 G ATPases associated with a variety of cellular activities
LCLEADBE_01985 2.2e-202 G Periplasmic binding protein domain
LCLEADBE_01986 1.9e-49 L Transposase
LCLEADBE_01987 9.8e-296 L PFAM Integrase catalytic
LCLEADBE_01988 3.6e-148 L IstB-like ATP binding protein
LCLEADBE_01989 8.4e-26 L Transposase
LCLEADBE_01990 1.1e-56 L Transposase
LCLEADBE_01991 2e-45 L Transposase DDE domain
LCLEADBE_01992 4e-40 L Transposase
LCLEADBE_01993 9.1e-281 cycA E Amino acid permease
LCLEADBE_01994 0.0 V FtsX-like permease family
LCLEADBE_01995 8.9e-130 V ABC transporter
LCLEADBE_01996 7e-270 aroP E aromatic amino acid transport protein AroP K03293
LCLEADBE_01997 1.3e-105 S Protein of unknown function, DUF624
LCLEADBE_01998 6.8e-153 rafG G ABC transporter permease
LCLEADBE_01999 4.4e-147 malC G Binding-protein-dependent transport system inner membrane component
LCLEADBE_02000 3.7e-185 K Psort location Cytoplasmic, score
LCLEADBE_02001 1.5e-255 amyE G Bacterial extracellular solute-binding protein
LCLEADBE_02002 1.2e-102 G Phosphoglycerate mutase family
LCLEADBE_02003 1.2e-59 S Protein of unknown function (DUF4235)
LCLEADBE_02004 4.2e-141 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
LCLEADBE_02005 0.0 pip S YhgE Pip domain protein
LCLEADBE_02006 1.3e-281 pip S YhgE Pip domain protein
LCLEADBE_02007 4e-40
LCLEADBE_02008 9.3e-10
LCLEADBE_02009 7.3e-146 cobB2 K Sir2 family
LCLEADBE_02010 1.5e-231 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
LCLEADBE_02011 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
LCLEADBE_02012 0.0 rafA 3.2.1.22 G Raffinose synthase or seed imbibition protein Sip1
LCLEADBE_02013 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
LCLEADBE_02014 2.9e-148 G Binding-protein-dependent transport system inner membrane component
LCLEADBE_02015 8.4e-165 G Binding-protein-dependent transport system inner membrane component
LCLEADBE_02016 1.2e-249 msmE G Bacterial extracellular solute-binding protein
LCLEADBE_02017 6.8e-233 G Protein of unknown function (DUF2961)
LCLEADBE_02018 5.2e-232 msmE G Bacterial extracellular solute-binding protein
LCLEADBE_02019 8.5e-190 K helix_turn _helix lactose operon repressor
LCLEADBE_02020 1.6e-188 K Periplasmic binding protein-like domain
LCLEADBE_02021 1.5e-155 G Binding-protein-dependent transport system inner membrane component
LCLEADBE_02022 4.1e-154 malC G Binding-protein-dependent transport system inner membrane component
LCLEADBE_02023 1.1e-245 msmE7 G Bacterial extracellular solute-binding protein
LCLEADBE_02024 1.2e-230 nagC GK ROK family
LCLEADBE_02025 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
LCLEADBE_02026 4e-80 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LCLEADBE_02027 0.0 yjcE P Sodium/hydrogen exchanger family
LCLEADBE_02028 1e-126 S membrane transporter protein
LCLEADBE_02029 7.8e-148 ypfH S Phospholipase/Carboxylesterase
LCLEADBE_02030 2.6e-155
LCLEADBE_02031 9e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
LCLEADBE_02032 1.2e-37
LCLEADBE_02033 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
LCLEADBE_02034 2e-16 K helix_turn _helix lactose operon repressor
LCLEADBE_02035 7.5e-86 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LCLEADBE_02036 1.6e-288 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
LCLEADBE_02037 3.5e-206 EGP Major facilitator Superfamily
LCLEADBE_02038 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCLEADBE_02039 7e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
LCLEADBE_02040 4.2e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LCLEADBE_02041 1.6e-271 KLT Domain of unknown function (DUF4032)
LCLEADBE_02042 8.8e-156
LCLEADBE_02043 1.4e-181 3.4.22.70 M Sortase family
LCLEADBE_02044 7.7e-281 M LPXTG-motif cell wall anchor domain protein
LCLEADBE_02045 0.0 S LPXTG-motif cell wall anchor domain protein
LCLEADBE_02046 3.4e-29 S LPXTG-motif cell wall anchor domain protein
LCLEADBE_02047 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
LCLEADBE_02048 6e-137 K UTRA domain
LCLEADBE_02049 2.2e-241 ulaA 2.7.1.194 S PTS system sugar-specific permease component
LCLEADBE_02050 3.7e-45 ulaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
LCLEADBE_02051 2.1e-73 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LCLEADBE_02052 3.6e-221 2.4.1.166 GT2 M Glycosyltransferase like family 2
LCLEADBE_02053 5.1e-142 K LytTr DNA-binding domain
LCLEADBE_02054 3.2e-229 T GHKL domain
LCLEADBE_02055 1.3e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCLEADBE_02057 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCLEADBE_02058 7.1e-89 nrdI F Probably involved in ribonucleotide reductase function
LCLEADBE_02059 3.1e-43 nrdH O Glutaredoxin
LCLEADBE_02060 3.4e-123 S Psort location CytoplasmicMembrane, score
LCLEADBE_02061 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
LCLEADBE_02062 3.1e-121 K Helix-turn-helix XRE-family like proteins
LCLEADBE_02063 6.8e-127 S Protein of unknown function (DUF3990)
LCLEADBE_02064 7e-71 kcsA U Ion channel
LCLEADBE_02065 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
LCLEADBE_02066 0.0 KLT Protein tyrosine kinase
LCLEADBE_02067 4.2e-138 O Thioredoxin
LCLEADBE_02069 8.2e-218 S G5
LCLEADBE_02070 4.4e-169 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LCLEADBE_02071 8.2e-179 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LCLEADBE_02072 4.8e-111 S LytR cell envelope-related transcriptional attenuator
LCLEADBE_02073 3.2e-283 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
LCLEADBE_02074 2.8e-166 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
LCLEADBE_02075 0.0
LCLEADBE_02076 0.0 murJ KLT MviN-like protein
LCLEADBE_02077 2.2e-177 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LCLEADBE_02078 8.8e-229 parB K Belongs to the ParB family
LCLEADBE_02079 9.6e-175 parA D CobQ CobB MinD ParA nucleotide binding domain protein
LCLEADBE_02080 1.2e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
LCLEADBE_02081 3e-93 jag S Putative single-stranded nucleic acids-binding domain
LCLEADBE_02082 5.8e-183 yidC U Membrane protein insertase, YidC Oxa1 family
LCLEADBE_02083 2.9e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LCLEADBE_02084 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)