ORF_ID e_value Gene_name EC_number CAZy COGs Description
MALPKPHM_00001 1.4e-215 M Glycosyl hydrolases family 25
MALPKPHM_00002 4e-59 S Bacteriophage holin of superfamily 6 (Holin_LLH)
MALPKPHM_00003 8.1e-45
MALPKPHM_00004 1.5e-14
MALPKPHM_00005 5.8e-300 S cellulase activity
MALPKPHM_00006 6.8e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
MALPKPHM_00032 1.3e-93 sigH K Sigma-70 region 2
MALPKPHM_00033 1.1e-297 ybeC E amino acid
MALPKPHM_00034 5.8e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MALPKPHM_00035 2.3e-195 cpoA GT4 M Glycosyltransferase, group 1 family protein
MALPKPHM_00036 4.5e-167 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MALPKPHM_00037 9e-220 patA 2.6.1.1 E Aminotransferase
MALPKPHM_00038 1.9e-43 ykuJ S Protein of unknown function (DUF1797)
MALPKPHM_00039 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MALPKPHM_00040 6.9e-80 perR P Belongs to the Fur family
MALPKPHM_00041 0.0 S peptidoglycan catabolic process
MALPKPHM_00042 1.8e-21
MALPKPHM_00043 5.1e-73 S Pfam:Phage_TTP_1
MALPKPHM_00044 3.4e-30
MALPKPHM_00045 2.9e-66 S exonuclease activity
MALPKPHM_00046 4e-40 S Phage head-tail joining protein
MALPKPHM_00047 5.5e-27 S Phage gp6-like head-tail connector protein
MALPKPHM_00048 1e-21 S peptidase activity
MALPKPHM_00049 7.9e-203 S peptidase activity
MALPKPHM_00050 1.3e-108 S peptidase activity
MALPKPHM_00051 3.9e-221 S Phage portal protein
MALPKPHM_00053 0.0 S Phage Terminase
MALPKPHM_00054 8.7e-78 S Phage terminase, small subunit
MALPKPHM_00055 1.3e-73 L HNH nucleases
MALPKPHM_00056 3.2e-50
MALPKPHM_00057 2.6e-97 S HNH endonuclease
MALPKPHM_00058 1.1e-236
MALPKPHM_00060 9.1e-25
MALPKPHM_00061 1.6e-76
MALPKPHM_00064 2.8e-29
MALPKPHM_00065 1.3e-32 S Protein of unknown function (DUF1642)
MALPKPHM_00067 6.1e-123 S DNA methylation
MALPKPHM_00069 3e-65 S magnesium ion binding
MALPKPHM_00070 3.7e-33
MALPKPHM_00072 3.4e-122 dnaC 3.4.21.53 L IstB-like ATP binding protein
MALPKPHM_00073 7.1e-91 S calcium ion binding
MALPKPHM_00074 4.2e-98 S Protein of unknown function (DUF669)
MALPKPHM_00075 4.7e-131 S AAA domain
MALPKPHM_00076 2e-80 S Siphovirus Gp157
MALPKPHM_00083 3.5e-12
MALPKPHM_00084 1.8e-131 S sequence-specific DNA binding
MALPKPHM_00085 5.8e-19 3.4.21.88 K Peptidase S24-like
MALPKPHM_00086 8e-91 3.1.21.3 V Type I restriction modification DNA specificity domain
MALPKPHM_00087 4.8e-21
MALPKPHM_00088 1.3e-09
MALPKPHM_00089 2.3e-212 L Belongs to the 'phage' integrase family
MALPKPHM_00092 6.5e-211 M Glycosyl hydrolases family 25
MALPKPHM_00093 1.8e-42 hol S Bacteriophage holin
MALPKPHM_00094 3.5e-53
MALPKPHM_00096 1.4e-53
MALPKPHM_00097 0.0 S peptidoglycan catabolic process
MALPKPHM_00098 0.0 S Phage tail protein
MALPKPHM_00099 0.0 S phage tail tape measure protein
MALPKPHM_00100 2.5e-60
MALPKPHM_00101 3.3e-50 S Phage tail assembly chaperone protein, TAC
MALPKPHM_00102 9.4e-104 S Phage tail tube protein
MALPKPHM_00103 7.8e-70 S Protein of unknown function (DUF3168)
MALPKPHM_00104 8.9e-57 S Bacteriophage HK97-gp10, putative tail-component
MALPKPHM_00105 1.4e-47
MALPKPHM_00106 1.9e-54 S Phage gp6-like head-tail connector protein
MALPKPHM_00107 4.2e-181 gpG
MALPKPHM_00108 6.6e-95 S Domain of unknown function (DUF4355)
MALPKPHM_00109 8e-67 S head morphogenesis protein, SPP1 gp7 family
MALPKPHM_00111 3.2e-248 S Phage portal protein
MALPKPHM_00112 1.1e-264 S Terminase RNAseH like domain
MALPKPHM_00113 8.9e-74 ps333 L Terminase small subunit
MALPKPHM_00114 5.8e-52
MALPKPHM_00115 2.3e-220 S GcrA cell cycle regulator
MALPKPHM_00116 6.8e-156
MALPKPHM_00117 9.1e-77
MALPKPHM_00120 2.7e-34
MALPKPHM_00121 1e-90 S Protein of unknown function (DUF1642)
MALPKPHM_00122 2.1e-18
MALPKPHM_00123 3.4e-64 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MALPKPHM_00124 2.7e-36
MALPKPHM_00125 1.4e-67
MALPKPHM_00126 3.4e-08 K Cro/C1-type HTH DNA-binding domain
MALPKPHM_00127 8.2e-66 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MALPKPHM_00128 6.4e-139 L Replication initiation and membrane attachment
MALPKPHM_00129 5e-133 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
MALPKPHM_00130 1.9e-150 recT L RecT family
MALPKPHM_00133 1.6e-13
MALPKPHM_00135 3.5e-97
MALPKPHM_00136 5.9e-76 K AntA/AntB antirepressor
MALPKPHM_00138 2.7e-33 K Helix-turn-helix XRE-family like proteins
MALPKPHM_00139 3.4e-55 3.4.21.88 K Helix-turn-helix domain
MALPKPHM_00140 2.9e-75 E Zn peptidase
MALPKPHM_00141 2.2e-65 S Domain of unknown function (DUF5067)
MALPKPHM_00142 1.1e-176
MALPKPHM_00144 5.5e-225 L Pfam:Integrase_AP2
MALPKPHM_00145 5e-165 L Belongs to the 'phage' integrase family
MALPKPHM_00146 2.3e-74 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MALPKPHM_00147 1.2e-214 hsdM 2.1.1.72 V type I restriction-modification system
MALPKPHM_00148 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MALPKPHM_00149 3.1e-212 ykiI
MALPKPHM_00150 4.2e-287 pip V domain protein
MALPKPHM_00151 3.4e-73 pip V domain protein
MALPKPHM_00152 2.1e-70 scrA 2.7.1.211 G phosphotransferase system
MALPKPHM_00153 6.7e-260 scrA 2.7.1.211 G phosphotransferase system
MALPKPHM_00154 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MALPKPHM_00155 2.8e-177 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
MALPKPHM_00156 5.5e-299 scrB 3.2.1.26 GH32 G invertase
MALPKPHM_00158 1.5e-158 azoB GM NmrA-like family
MALPKPHM_00159 6.5e-234 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MALPKPHM_00160 2e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MALPKPHM_00161 5.4e-147 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MALPKPHM_00162 6.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MALPKPHM_00163 1.2e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MALPKPHM_00164 2.3e-51 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MALPKPHM_00165 3.1e-223 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MALPKPHM_00166 7.3e-127 IQ reductase
MALPKPHM_00167 2.5e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MALPKPHM_00168 1.5e-172 fabK 1.3.1.9 S Nitronate monooxygenase
MALPKPHM_00169 4.5e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MALPKPHM_00170 3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MALPKPHM_00171 2.1e-76 marR K Winged helix DNA-binding domain
MALPKPHM_00172 9e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MALPKPHM_00173 7.4e-191 I carboxylic ester hydrolase activity
MALPKPHM_00174 3.5e-227 bdhA C Iron-containing alcohol dehydrogenase
MALPKPHM_00175 7.1e-62 P Rhodanese-like domain
MALPKPHM_00176 6.8e-84 yetL K helix_turn_helix multiple antibiotic resistance protein
MALPKPHM_00177 3.5e-80 2.7.7.65 T diguanylate cyclase activity
MALPKPHM_00178 4.5e-201 ydaN S Bacterial cellulose synthase subunit
MALPKPHM_00179 2.1e-182 ydaM M Glycosyl transferase family group 2
MALPKPHM_00180 3.2e-79 S Protein conserved in bacteria
MALPKPHM_00181 1.7e-74
MALPKPHM_00182 2.8e-80 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
MALPKPHM_00183 2.9e-56 2.7.7.65 T diguanylate cyclase
MALPKPHM_00184 2.3e-169 nox C NADH oxidase
MALPKPHM_00185 2.8e-72 yliE T Putative diguanylate phosphodiesterase
MALPKPHM_00186 3.7e-67 K MarR family
MALPKPHM_00187 1.8e-11 S response to antibiotic
MALPKPHM_00188 8e-88 S Putative esterase
MALPKPHM_00189 3.1e-46 S Putative esterase
MALPKPHM_00190 5.8e-181
MALPKPHM_00191 1e-102 rmaB K Transcriptional regulator, MarR family
MALPKPHM_00192 1.2e-85 F NUDIX domain
MALPKPHM_00193 7.9e-175 U Major Facilitator Superfamily
MALPKPHM_00194 4.9e-37 K helix_turn_helix, Arsenical Resistance Operon Repressor
MALPKPHM_00195 3.5e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MALPKPHM_00196 4.4e-29
MALPKPHM_00197 4.9e-124 S zinc-ribbon domain
MALPKPHM_00198 5.3e-198 pbpX1 V Beta-lactamase
MALPKPHM_00199 1.5e-181 K AI-2E family transporter
MALPKPHM_00200 5.4e-127 srtA 3.4.22.70 M Sortase family
MALPKPHM_00201 4.5e-65 gtcA S Teichoic acid glycosylation protein
MALPKPHM_00202 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MALPKPHM_00203 1.2e-168 gbuC E glycine betaine
MALPKPHM_00204 9.4e-126 proW E glycine betaine
MALPKPHM_00205 1e-221 gbuA 3.6.3.32 E glycine betaine
MALPKPHM_00206 5.2e-133 sfsA S Belongs to the SfsA family
MALPKPHM_00207 1.7e-65 usp1 T Universal stress protein family
MALPKPHM_00208 3.1e-250 yxbA 6.3.1.12 S ATP-grasp enzyme
MALPKPHM_00209 7.1e-153 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MALPKPHM_00210 1.3e-282 thrC 4.2.3.1 E Threonine synthase
MALPKPHM_00211 5.2e-231 hom 1.1.1.3 E homoserine dehydrogenase
MALPKPHM_00212 6.7e-251 yclM 2.7.2.4 E Belongs to the aspartokinase family
MALPKPHM_00213 2.3e-167 yqiK S SPFH domain / Band 7 family
MALPKPHM_00214 9.7e-68
MALPKPHM_00215 1.2e-154 pfoS S Phosphotransferase system, EIIC
MALPKPHM_00216 5e-179 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MALPKPHM_00217 2.1e-216 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MALPKPHM_00218 4.4e-36 E lactoylglutathione lyase activity
MALPKPHM_00219 6.4e-120 WQ51_05710 S Mitochondrial biogenesis AIM24
MALPKPHM_00220 2.2e-145 S Alpha/beta hydrolase family
MALPKPHM_00221 1.2e-100 K Bacterial regulatory proteins, tetR family
MALPKPHM_00222 4.7e-173 XK27_06930 V domain protein
MALPKPHM_00223 4.8e-171 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MALPKPHM_00224 4.2e-246 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00225 2.7e-55 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00226 1.6e-175 G PTS system sugar-specific permease component
MALPKPHM_00227 6.7e-31 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_00228 9.4e-68 S Uncharacterised protein family UPF0047
MALPKPHM_00229 6.5e-48 kdsD 5.3.1.13 M SIS domain
MALPKPHM_00230 1.9e-84 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MALPKPHM_00231 1.2e-44 5.3.1.27 M arabinose-5-phosphate isomerase activity
MALPKPHM_00232 0.0 asnB 6.3.5.4 E Asparagine synthase
MALPKPHM_00233 3.6e-10
MALPKPHM_00234 7.5e-205 S Calcineurin-like phosphoesterase
MALPKPHM_00235 8.8e-162 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MALPKPHM_00236 5.1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MALPKPHM_00237 1.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MALPKPHM_00238 1.3e-165 natA S ABC transporter
MALPKPHM_00239 3.2e-210 ysdA CP ABC-2 family transporter protein
MALPKPHM_00240 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
MALPKPHM_00241 2.4e-161 CcmA V ABC transporter
MALPKPHM_00242 7.4e-115 VPA0052 I ABC-2 family transporter protein
MALPKPHM_00243 1.4e-144 IQ reductase
MALPKPHM_00244 7.7e-186 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MALPKPHM_00245 1.3e-68 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MALPKPHM_00246 0.0 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MALPKPHM_00247 1.7e-159 licT K CAT RNA binding domain
MALPKPHM_00248 2.2e-288 cydC V ABC transporter transmembrane region
MALPKPHM_00249 3.5e-310 cydD CO ABC transporter transmembrane region
MALPKPHM_00250 4.9e-75 ynhH S NusG domain II
MALPKPHM_00251 2.4e-174 M Peptidoglycan-binding domain 1 protein
MALPKPHM_00252 8e-37 XK27_02675 K Acetyltransferase (GNAT) domain
MALPKPHM_00253 5.1e-114 S CRISPR-associated protein (Cas_Csn2)
MALPKPHM_00254 4.8e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MALPKPHM_00255 2.3e-168 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MALPKPHM_00256 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MALPKPHM_00257 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MALPKPHM_00258 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MALPKPHM_00259 5e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MALPKPHM_00260 1.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
MALPKPHM_00261 2e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
MALPKPHM_00262 1e-171 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MALPKPHM_00263 4.6e-38
MALPKPHM_00264 4.9e-87
MALPKPHM_00265 2.7e-24
MALPKPHM_00266 1.5e-161 yicL EG EamA-like transporter family
MALPKPHM_00267 1.5e-112 tag 3.2.2.20 L glycosylase
MALPKPHM_00268 4.2e-77 usp5 T universal stress protein
MALPKPHM_00269 4.7e-64 K Helix-turn-helix XRE-family like proteins
MALPKPHM_00270 1.1e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
MALPKPHM_00271 1.3e-223 queG 1.17.99.6 C Domain of unknown function (DUF1730)
MALPKPHM_00272 1.4e-62
MALPKPHM_00273 1.4e-87 bioY S BioY family
MALPKPHM_00275 4.2e-102 Q methyltransferase
MALPKPHM_00276 9.4e-101 T Sh3 type 3 domain protein
MALPKPHM_00277 2.1e-114 yfeJ 6.3.5.2 F glutamine amidotransferase
MALPKPHM_00278 8.8e-136 S Uncharacterized protein conserved in bacteria (DUF2263)
MALPKPHM_00279 7.6e-258 yhdP S Transporter associated domain
MALPKPHM_00280 1.9e-144 S Alpha beta hydrolase
MALPKPHM_00281 7.8e-196 I Acyltransferase
MALPKPHM_00282 1.2e-261 lmrB EGP Major facilitator Superfamily
MALPKPHM_00283 1.5e-83 S Domain of unknown function (DUF4811)
MALPKPHM_00284 2.3e-93 maf D nucleoside-triphosphate diphosphatase activity
MALPKPHM_00285 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MALPKPHM_00286 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MALPKPHM_00287 0.0 ydaO E amino acid
MALPKPHM_00288 1.1e-56 S Domain of unknown function (DUF1827)
MALPKPHM_00289 7.2e-275 L PFAM Integrase core domain
MALPKPHM_00290 4.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MALPKPHM_00291 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MALPKPHM_00292 4.2e-110 ydiL S CAAX protease self-immunity
MALPKPHM_00293 3.7e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MALPKPHM_00294 1e-193
MALPKPHM_00295 3.9e-159 ytrB V ABC transporter
MALPKPHM_00296 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
MALPKPHM_00297 4.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MALPKPHM_00298 0.0 uup S ABC transporter, ATP-binding protein
MALPKPHM_00299 3.6e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_00300 1.8e-187 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MALPKPHM_00301 1.5e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MALPKPHM_00302 7e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MALPKPHM_00303 4.2e-104
MALPKPHM_00304 7.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
MALPKPHM_00305 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
MALPKPHM_00306 1.1e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
MALPKPHM_00307 2.6e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MALPKPHM_00308 1.7e-57 yabA L Involved in initiation control of chromosome replication
MALPKPHM_00309 8.2e-174 holB 2.7.7.7 L DNA polymerase III
MALPKPHM_00310 7.8e-52 yaaQ S Cyclic-di-AMP receptor
MALPKPHM_00311 7.4e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MALPKPHM_00312 8.7e-38 S Protein of unknown function (DUF2508)
MALPKPHM_00313 5.6e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MALPKPHM_00314 1.5e-33 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MALPKPHM_00315 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MALPKPHM_00316 7.5e-86 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MALPKPHM_00317 4.7e-49
MALPKPHM_00318 1.5e-106 rsmC 2.1.1.172 J Methyltransferase
MALPKPHM_00319 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MALPKPHM_00320 1.5e-68
MALPKPHM_00321 4.7e-171 ccpB 5.1.1.1 K lacI family
MALPKPHM_00322 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
MALPKPHM_00323 4.2e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MALPKPHM_00324 2.5e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MALPKPHM_00325 7.7e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MALPKPHM_00326 7.2e-275 L PFAM Integrase core domain
MALPKPHM_00327 9.8e-225 mdtG EGP Major facilitator Superfamily
MALPKPHM_00328 1.6e-151 K acetyltransferase
MALPKPHM_00329 1.7e-88
MALPKPHM_00330 5e-221 yceI G Sugar (and other) transporter
MALPKPHM_00332 4.9e-211 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MALPKPHM_00333 1.4e-300 frvR K Mga helix-turn-helix domain
MALPKPHM_00334 1.3e-295 frvR K Mga helix-turn-helix domain
MALPKPHM_00335 3.2e-267 lysP E amino acid
MALPKPHM_00337 5.3e-130 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MALPKPHM_00338 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MALPKPHM_00339 1.6e-97
MALPKPHM_00340 1.3e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
MALPKPHM_00341 1.8e-187 S Bacterial protein of unknown function (DUF916)
MALPKPHM_00342 9.9e-103
MALPKPHM_00343 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MALPKPHM_00344 5e-159 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MALPKPHM_00345 1.3e-156 I alpha/beta hydrolase fold
MALPKPHM_00346 7.4e-48
MALPKPHM_00347 6.5e-69
MALPKPHM_00348 1.7e-159 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MALPKPHM_00349 7.2e-124 citR K FCD
MALPKPHM_00350 1.4e-264 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
MALPKPHM_00351 5.2e-101 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MALPKPHM_00352 2.1e-285 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
MALPKPHM_00353 4.5e-155 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
MALPKPHM_00354 2.7e-46 citD C Covalent carrier of the coenzyme of citrate lyase
MALPKPHM_00355 7.1e-181 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MALPKPHM_00357 1.3e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
MALPKPHM_00358 1.8e-37 gcdC 2.3.1.12 I Biotin-requiring enzyme
MALPKPHM_00359 1.2e-49
MALPKPHM_00360 1.8e-240 citM C Citrate transporter
MALPKPHM_00361 1.1e-40
MALPKPHM_00362 7.3e-98 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MALPKPHM_00363 3e-87 K Acetyltransferase (GNAT) domain
MALPKPHM_00364 6.6e-105 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MALPKPHM_00365 3.7e-57 K Transcriptional regulator PadR-like family
MALPKPHM_00366 9.5e-86 ORF00048
MALPKPHM_00367 6.8e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MALPKPHM_00368 2.1e-163 yjjC V ABC transporter
MALPKPHM_00369 1.5e-278 M Exporter of polyketide antibiotics
MALPKPHM_00370 9.8e-112 K Transcriptional regulator
MALPKPHM_00371 3.2e-256 ypiB EGP Major facilitator Superfamily
MALPKPHM_00372 6.7e-128 S membrane transporter protein
MALPKPHM_00373 9.2e-184 K Helix-turn-helix domain
MALPKPHM_00374 1.8e-147 L PFAM Integrase catalytic region
MALPKPHM_00375 2e-89 L Helix-turn-helix domain
MALPKPHM_00376 3.6e-157 S Alpha beta hydrolase
MALPKPHM_00377 3.6e-61 yvoA_1 K Transcriptional regulator, GntR family
MALPKPHM_00378 1.4e-127 skfE V ATPases associated with a variety of cellular activities
MALPKPHM_00379 1.8e-16
MALPKPHM_00380 6.5e-162 oppF P Oligopeptide/dipeptide transporter, C-terminal region
MALPKPHM_00381 4.7e-199 oppD P Oligopeptide/dipeptide transporter, C-terminal region
MALPKPHM_00382 8.3e-48
MALPKPHM_00383 3e-173 amiD P N-terminal TM domain of oligopeptide transport permease C
MALPKPHM_00384 6.5e-168 oppB P Binding-protein-dependent transport system inner membrane component
MALPKPHM_00385 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
MALPKPHM_00386 5.6e-37
MALPKPHM_00387 1.2e-281 V ABC transporter transmembrane region
MALPKPHM_00388 2.3e-282 V ABC transporter transmembrane region
MALPKPHM_00389 9.3e-68 S Iron-sulphur cluster biosynthesis
MALPKPHM_00390 4.6e-133 2.7.1.39 S Phosphotransferase enzyme family
MALPKPHM_00391 7.4e-114 zmp3 O Zinc-dependent metalloprotease
MALPKPHM_00392 1.6e-23 WQ51_00220 K Helix-turn-helix XRE-family like proteins
MALPKPHM_00394 0.0 lytN 3.5.1.104 M LysM domain
MALPKPHM_00396 1.8e-48 lciIC K Helix-turn-helix XRE-family like proteins
MALPKPHM_00397 6.8e-37 L Plasmid pRiA4b ORF-3-like protein
MALPKPHM_00398 3.2e-28 L Transposase DDE domain group 1
MALPKPHM_00399 1.7e-07 L PFAM Transposase, IS4-like
MALPKPHM_00401 7.5e-29 K Cro/C1-type HTH DNA-binding domain
MALPKPHM_00402 3.8e-117 dam 2.1.1.72 H Site-specific DNA-methyltransferase (adenine-specific)
MALPKPHM_00403 2e-83 ecoRVR L Restriction endonuclease EcoRV
MALPKPHM_00404 6.7e-65 O unfolded protein binding
MALPKPHM_00405 4.9e-91 2.1.1.113 L DNA methylase
MALPKPHM_00406 9.9e-299 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MALPKPHM_00407 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
MALPKPHM_00408 2.8e-52
MALPKPHM_00409 2.4e-41
MALPKPHM_00410 5.3e-275 pipD E Dipeptidase
MALPKPHM_00411 1.2e-82 ykhA 3.1.2.20 I Thioesterase superfamily
MALPKPHM_00412 0.0 helD 3.6.4.12 L DNA helicase
MALPKPHM_00413 6.8e-27
MALPKPHM_00414 0.0 yjbQ P TrkA C-terminal domain protein
MALPKPHM_00415 3.2e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MALPKPHM_00416 3.5e-82 yjhE S Phage tail protein
MALPKPHM_00417 3.7e-217 mntH P H( )-stimulated, divalent metal cation uptake system
MALPKPHM_00418 1.5e-183 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MALPKPHM_00419 2.7e-128 pgm3 G Phosphoglycerate mutase family
MALPKPHM_00420 2.7e-171 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MALPKPHM_00421 0.0 V FtsX-like permease family
MALPKPHM_00422 1.4e-136 cysA V ABC transporter, ATP-binding protein
MALPKPHM_00423 0.0 E amino acid
MALPKPHM_00424 1.4e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
MALPKPHM_00425 9.9e-236 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MALPKPHM_00426 5.7e-111 nodB3 G Polysaccharide deacetylase
MALPKPHM_00427 0.0 M Sulfatase
MALPKPHM_00428 3e-174 S EpsG family
MALPKPHM_00429 4.3e-83 epsG 2.7.10.1 D Capsular exopolysaccharide family
MALPKPHM_00430 1.6e-99 ywqC M capsule polysaccharide biosynthetic process
MALPKPHM_00431 1.6e-247 S polysaccharide biosynthetic process
MALPKPHM_00432 3.8e-199 M Glycosyl transferases group 1
MALPKPHM_00433 9.4e-122 tagF 2.7.8.12 M Glycosyltransferase like family 2
MALPKPHM_00434 1.2e-223 S Bacterial membrane protein, YfhO
MALPKPHM_00435 4.9e-301 M Glycosyl hydrolases family 25
MALPKPHM_00436 2e-179 M Dolichyl-phosphate-mannose-protein mannosyltransferase
MALPKPHM_00437 1.9e-112 icaC M Acyltransferase family
MALPKPHM_00438 5.8e-159 ykoT GT2 M Glycosyl transferase family 2
MALPKPHM_00439 7.8e-200 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MALPKPHM_00440 5.1e-85
MALPKPHM_00441 1.5e-253 wcaJ M Bacterial sugar transferase
MALPKPHM_00442 1.1e-133 M Glycosyltransferase sugar-binding region containing DXD motif
MALPKPHM_00443 4.8e-113 tuaG GT2 M Glycosyltransferase like family 2
MALPKPHM_00444 3.5e-174 cps2D 5.1.3.2 M RmlD substrate binding domain
MALPKPHM_00445 1.1e-110 glnP P ABC transporter permease
MALPKPHM_00446 2.3e-108 gluC P ABC transporter permease
MALPKPHM_00447 2.2e-148 glnH ET ABC transporter substrate-binding protein
MALPKPHM_00449 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MALPKPHM_00450 2.8e-171
MALPKPHM_00452 9.6e-85 zur P Belongs to the Fur family
MALPKPHM_00453 1.8e-08
MALPKPHM_00454 2.1e-111 gmk2 2.7.4.8 F Guanylate kinase
MALPKPHM_00455 4.7e-67 K Acetyltransferase (GNAT) domain
MALPKPHM_00456 3.7e-120 spl M NlpC/P60 family
MALPKPHM_00457 9.1e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MALPKPHM_00458 6.9e-162 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MALPKPHM_00459 1.4e-53 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
MALPKPHM_00460 5.9e-174 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MALPKPHM_00461 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
MALPKPHM_00462 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MALPKPHM_00463 4.4e-285 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
MALPKPHM_00464 8.8e-199 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
MALPKPHM_00465 1.7e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MALPKPHM_00466 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MALPKPHM_00467 1.8e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MALPKPHM_00468 2.5e-116 ylcC 3.4.22.70 M Sortase family
MALPKPHM_00469 1.7e-143 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MALPKPHM_00470 0.0 fbp 3.1.3.11 G phosphatase activity
MALPKPHM_00471 5.7e-65 nrp 1.20.4.1 P ArsC family
MALPKPHM_00472 0.0 clpL O associated with various cellular activities
MALPKPHM_00473 2e-143 ywqE 3.1.3.48 GM PHP domain protein
MALPKPHM_00474 2.4e-156 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MALPKPHM_00475 3.5e-75 cpsE M Bacterial sugar transferase
MALPKPHM_00476 1.5e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MALPKPHM_00477 1.3e-201 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MALPKPHM_00478 2.3e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MALPKPHM_00479 2.2e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MALPKPHM_00480 1.6e-63 wcmJ S SPTR Capsular exopolysaccharide biosynthesis protein (Wzm)
MALPKPHM_00481 1.4e-57 cps1B GT2,GT4 M Glycosyl transferases group 1
MALPKPHM_00482 6.6e-07 S EpsG family
MALPKPHM_00483 2.5e-72 rgpB GT2 M Glycosyl transferase family 2
MALPKPHM_00484 5.3e-25 rfbF GT2 V Glycosyl transferase, family 2
MALPKPHM_00485 7.4e-43 wbbK M Glycosyl transferases group 1
MALPKPHM_00486 5.2e-38 wbbL S Glycosyl transferase family 2
MALPKPHM_00487 3e-89 cps2J S Polysaccharide biosynthesis protein
MALPKPHM_00488 9.9e-111 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MALPKPHM_00489 1.3e-109 epsB M biosynthesis protein
MALPKPHM_00490 9.8e-132 E lipolytic protein G-D-S-L family
MALPKPHM_00491 7.9e-26 ccl S QueT transporter
MALPKPHM_00492 9.3e-127 IQ Enoyl-(Acyl carrier protein) reductase
MALPKPHM_00493 4.8e-37 XK27_01315 S Protein of unknown function (DUF2829)
MALPKPHM_00494 5e-48 K Cro/C1-type HTH DNA-binding domain
MALPKPHM_00495 3.3e-115 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
MALPKPHM_00496 1.5e-180 oppF P Belongs to the ABC transporter superfamily
MALPKPHM_00497 1.9e-197 oppD P Belongs to the ABC transporter superfamily
MALPKPHM_00498 3.1e-176 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MALPKPHM_00499 3e-162 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MALPKPHM_00500 3.7e-304 oppA E ABC transporter, substratebinding protein
MALPKPHM_00501 6.6e-252 EGP Major facilitator Superfamily
MALPKPHM_00502 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MALPKPHM_00503 3.4e-129 yrjD S LUD domain
MALPKPHM_00504 3.6e-290 lutB C 4Fe-4S dicluster domain
MALPKPHM_00505 1.6e-148 lutA C Cysteine-rich domain
MALPKPHM_00506 9.1e-101
MALPKPHM_00507 9.5e-53 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MALPKPHM_00508 1.6e-210 S Bacterial protein of unknown function (DUF871)
MALPKPHM_00509 7.9e-70 S Domain of unknown function (DUF3284)
MALPKPHM_00510 2.2e-268 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MALPKPHM_00511 0.0 rafA 3.2.1.22 G alpha-galactosidase
MALPKPHM_00512 5.9e-132 S Belongs to the UPF0246 family
MALPKPHM_00513 1.5e-132 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
MALPKPHM_00514 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
MALPKPHM_00515 3.9e-110
MALPKPHM_00516 9e-102 S WxL domain surface cell wall-binding
MALPKPHM_00517 1.3e-145 frlD 2.7.1.218 G pfkB family carbohydrate kinase
MALPKPHM_00518 2.1e-288 G Phosphodiester glycosidase
MALPKPHM_00520 3.2e-289 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
MALPKPHM_00521 1.2e-205 S Protein of unknown function (DUF917)
MALPKPHM_00522 2.1e-222 F Permease for cytosine/purines, uracil, thiamine, allantoin
MALPKPHM_00523 1.2e-122
MALPKPHM_00524 0.0 S Protein of unknown function (DUF1524)
MALPKPHM_00525 8.7e-27
MALPKPHM_00526 2.4e-289 2.4.1.52 GT4 M Glycosyl transferases group 1
MALPKPHM_00527 3.6e-301 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MALPKPHM_00528 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MALPKPHM_00529 1.3e-96 yqaB S Acetyltransferase (GNAT) domain
MALPKPHM_00530 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MALPKPHM_00531 4.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MALPKPHM_00532 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MALPKPHM_00533 2.3e-265 nylA 3.5.1.4 J Belongs to the amidase family
MALPKPHM_00534 3.6e-91 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
MALPKPHM_00535 4.2e-87 S ECF transporter, substrate-specific component
MALPKPHM_00536 3.1e-63 S Domain of unknown function (DUF4430)
MALPKPHM_00537 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
MALPKPHM_00538 5.9e-79 F nucleoside 2-deoxyribosyltransferase
MALPKPHM_00539 7.1e-158 S Alpha/beta hydrolase of unknown function (DUF915)
MALPKPHM_00540 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
MALPKPHM_00541 1.5e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MALPKPHM_00542 8.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MALPKPHM_00543 2e-169 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MALPKPHM_00544 1.9e-164 menA 2.5.1.74 M UbiA prenyltransferase family
MALPKPHM_00545 3.5e-194 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MALPKPHM_00546 3.1e-228 tnpB L Putative transposase DNA-binding domain
MALPKPHM_00547 4.6e-139 cad S FMN_bind
MALPKPHM_00548 0.0 ndh 1.6.99.3 C NADH dehydrogenase
MALPKPHM_00549 6.9e-80 ynhH S NusG domain II
MALPKPHM_00550 5.2e-99 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
MALPKPHM_00551 1.3e-179 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MALPKPHM_00552 2.7e-32
MALPKPHM_00553 4.4e-38
MALPKPHM_00555 1.4e-156 V ATPases associated with a variety of cellular activities
MALPKPHM_00556 5.8e-217
MALPKPHM_00557 1.9e-195
MALPKPHM_00558 1.3e-122 1.5.1.40 S Rossmann-like domain
MALPKPHM_00559 4.2e-192 XK27_00915 C Luciferase-like monooxygenase
MALPKPHM_00560 1.2e-97 yacP S YacP-like NYN domain
MALPKPHM_00561 2.1e-143 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MALPKPHM_00562 5.5e-74 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MALPKPHM_00563 2.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MALPKPHM_00564 5.5e-145 K sequence-specific DNA binding
MALPKPHM_00565 7.4e-245 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
MALPKPHM_00566 9.5e-98
MALPKPHM_00568 3.3e-259 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MALPKPHM_00569 1.1e-142 yhfC S Putative membrane peptidase family (DUF2324)
MALPKPHM_00570 1.7e-158 S Membrane
MALPKPHM_00571 2.8e-61 K helix_turn_helix gluconate operon transcriptional repressor
MALPKPHM_00572 3.7e-296 V ABC transporter transmembrane region
MALPKPHM_00573 3.5e-228 inlJ M MucBP domain
MALPKPHM_00574 1.9e-69 S ABC-2 family transporter protein
MALPKPHM_00575 3.1e-95 V ABC transporter, ATP-binding protein
MALPKPHM_00576 1.4e-108 K sequence-specific DNA binding
MALPKPHM_00577 1.8e-201 yacL S domain protein
MALPKPHM_00578 8.5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MALPKPHM_00579 5.6e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
MALPKPHM_00580 2.4e-49 HA62_12640 S GCN5-related N-acetyl-transferase
MALPKPHM_00581 3.3e-77 L Resolvase, N-terminal
MALPKPHM_00582 3.1e-228 tnpB L Putative transposase DNA-binding domain
MALPKPHM_00584 1.5e-255 pepC 3.4.22.40 E aminopeptidase
MALPKPHM_00585 3.8e-262 pepC 3.4.22.40 E Peptidase C1-like family
MALPKPHM_00586 2.9e-196
MALPKPHM_00587 2.5e-209 S ABC-2 family transporter protein
MALPKPHM_00588 6.2e-165 V ATPases associated with a variety of cellular activities
MALPKPHM_00589 0.0 kup P Transport of potassium into the cell
MALPKPHM_00590 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
MALPKPHM_00591 1.5e-92 ccpN K Domain in cystathionine beta-synthase and other proteins.
MALPKPHM_00592 2.9e-122 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MALPKPHM_00593 2.4e-201 ltrA S Bacterial low temperature requirement A protein (LtrA)
MALPKPHM_00594 7.2e-46
MALPKPHM_00595 9.7e-167 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MALPKPHM_00596 3.7e-18 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MALPKPHM_00597 8.8e-09 yhjA S CsbD-like
MALPKPHM_00598 5.7e-153 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MALPKPHM_00599 9.2e-191 EGP Major facilitator Superfamily
MALPKPHM_00600 1.9e-114 udp 2.4.2.3, 3.2.2.4 F Phosphorylase superfamily
MALPKPHM_00601 8.9e-170 EGP Major facilitator Superfamily
MALPKPHM_00602 2.2e-96 KT Purine catabolism regulatory protein-like family
MALPKPHM_00603 5.4e-08
MALPKPHM_00604 2.5e-32
MALPKPHM_00605 7.4e-34
MALPKPHM_00606 1.1e-223 pimH EGP Major facilitator Superfamily
MALPKPHM_00607 2.4e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MALPKPHM_00608 3.5e-149 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MALPKPHM_00610 2.8e-91
MALPKPHM_00611 9.8e-33 bacI V MacB-like periplasmic core domain
MALPKPHM_00612 1.4e-55 macB V ABC transporter, ATP-binding protein
MALPKPHM_00614 1.4e-126 3.4.22.70 M Sortase family
MALPKPHM_00615 4.2e-289 M Cna protein B-type domain
MALPKPHM_00616 1.2e-260 M domain protein
MALPKPHM_00617 0.0 M domain protein
MALPKPHM_00618 9.6e-103
MALPKPHM_00619 2.3e-54 S CAAX protease self-immunity
MALPKPHM_00620 1.2e-222 N Uncharacterized conserved protein (DUF2075)
MALPKPHM_00621 1.8e-206 MA20_36090 S Protein of unknown function (DUF2974)
MALPKPHM_00622 2.7e-96 K Helix-turn-helix XRE-family like proteins
MALPKPHM_00623 1.4e-56 K Transcriptional regulator PadR-like family
MALPKPHM_00624 1.1e-136
MALPKPHM_00625 1.7e-134
MALPKPHM_00626 9e-44 S Enterocin A Immunity
MALPKPHM_00627 2.3e-185 tas C Aldo/keto reductase family
MALPKPHM_00628 1.9e-152 L PFAM Integrase catalytic region
MALPKPHM_00629 1.4e-90 L Helix-turn-helix domain
MALPKPHM_00630 1.1e-253 yjjP S Putative threonine/serine exporter
MALPKPHM_00631 2.3e-57
MALPKPHM_00632 5.1e-222 mesE M Transport protein ComB
MALPKPHM_00633 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MALPKPHM_00635 1e-78 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MALPKPHM_00636 6.8e-131 plnD K LytTr DNA-binding domain
MALPKPHM_00639 3.2e-44 spiA S Enterocin A Immunity
MALPKPHM_00640 1.3e-20
MALPKPHM_00644 1.1e-136 S CAAX protease self-immunity
MALPKPHM_00645 1.6e-68 K Transcriptional regulator
MALPKPHM_00646 2.5e-248 EGP Major Facilitator Superfamily
MALPKPHM_00647 2.4e-53
MALPKPHM_00648 3.3e-53 S Enterocin A Immunity
MALPKPHM_00649 3e-181 S Aldo keto reductase
MALPKPHM_00650 5.1e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MALPKPHM_00651 9.5e-214 yqiG C Oxidoreductase
MALPKPHM_00652 1.3e-16 S Short C-terminal domain
MALPKPHM_00653 8.1e-252 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MALPKPHM_00654 3.3e-131
MALPKPHM_00655 6.8e-18
MALPKPHM_00656 1.2e-278 mntH P H( )-stimulated, divalent metal cation uptake system
MALPKPHM_00657 0.0 pacL P P-type ATPase
MALPKPHM_00658 9.8e-64
MALPKPHM_00659 6.5e-227 EGP Major Facilitator Superfamily
MALPKPHM_00660 2.1e-311 mco Q Multicopper oxidase
MALPKPHM_00661 1e-24
MALPKPHM_00662 1.9e-110 2.5.1.105 P Cation efflux family
MALPKPHM_00663 8.7e-51 czrA K Transcriptional regulator, ArsR family
MALPKPHM_00664 5.4e-175 sitA P Belongs to the bacterial solute-binding protein 9 family
MALPKPHM_00665 9.5e-145 mtsB U ABC 3 transport family
MALPKPHM_00666 1.3e-131 mntB 3.6.3.35 P ABC transporter
MALPKPHM_00667 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MALPKPHM_00668 7.7e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
MALPKPHM_00669 9.3e-118 GM NmrA-like family
MALPKPHM_00670 1.8e-84
MALPKPHM_00671 3e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
MALPKPHM_00672 1.8e-19
MALPKPHM_00674 7.5e-53 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MALPKPHM_00675 8.2e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MALPKPHM_00676 1.2e-285 G MFS/sugar transport protein
MALPKPHM_00677 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase concanavalin-like domain
MALPKPHM_00678 1e-168 ssuA P NMT1-like family
MALPKPHM_00679 2.5e-294 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
MALPKPHM_00680 2.3e-234 yfiQ I Acyltransferase family
MALPKPHM_00681 4.9e-120 ssuB P ATPases associated with a variety of cellular activities
MALPKPHM_00682 2.3e-145 ssuC U Binding-protein-dependent transport system inner membrane component
MALPKPHM_00683 7.7e-123 S B3/4 domain
MALPKPHM_00684 2.5e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MALPKPHM_00685 9.5e-14
MALPKPHM_00686 0.0 V ABC transporter
MALPKPHM_00687 0.0 V ATPases associated with a variety of cellular activities
MALPKPHM_00688 1.8e-207 EGP Transmembrane secretion effector
MALPKPHM_00689 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MALPKPHM_00690 7e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MALPKPHM_00691 1.9e-104 K Bacterial regulatory proteins, tetR family
MALPKPHM_00692 2.9e-185 yxeA V FtsX-like permease family
MALPKPHM_00693 3.5e-126 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
MALPKPHM_00694 6.4e-34
MALPKPHM_00695 2.6e-135 tipA K TipAS antibiotic-recognition domain
MALPKPHM_00697 5.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MALPKPHM_00698 1.6e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MALPKPHM_00699 2.1e-157 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MALPKPHM_00700 2.6e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MALPKPHM_00701 6.7e-119
MALPKPHM_00702 3.1e-60 rplQ J Ribosomal protein L17
MALPKPHM_00703 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MALPKPHM_00704 2e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MALPKPHM_00705 2.1e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MALPKPHM_00706 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MALPKPHM_00707 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MALPKPHM_00708 1.4e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MALPKPHM_00709 9.8e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MALPKPHM_00710 2.2e-62 rplO J Binds to the 23S rRNA
MALPKPHM_00711 1.7e-24 rpmD J Ribosomal protein L30
MALPKPHM_00712 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MALPKPHM_00713 4.6e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MALPKPHM_00714 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MALPKPHM_00715 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MALPKPHM_00716 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MALPKPHM_00717 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MALPKPHM_00718 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MALPKPHM_00719 1.4e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MALPKPHM_00720 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
MALPKPHM_00721 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MALPKPHM_00722 3.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MALPKPHM_00723 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MALPKPHM_00724 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MALPKPHM_00725 3.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MALPKPHM_00726 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MALPKPHM_00727 5.9e-109 rplD J Forms part of the polypeptide exit tunnel
MALPKPHM_00728 3e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MALPKPHM_00729 8.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
MALPKPHM_00730 1.2e-68 psiE S Phosphate-starvation-inducible E
MALPKPHM_00731 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
MALPKPHM_00732 1.1e-197 yfjR K WYL domain
MALPKPHM_00733 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MALPKPHM_00734 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MALPKPHM_00735 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MALPKPHM_00736 0.0 M domain protein
MALPKPHM_00737 3.4e-83 3.4.23.43
MALPKPHM_00738 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MALPKPHM_00739 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MALPKPHM_00740 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MALPKPHM_00741 3.6e-79 ctsR K Belongs to the CtsR family
MALPKPHM_00750 1.7e-43 trxC O Belongs to the thioredoxin family
MALPKPHM_00751 2.8e-132 thrE S Putative threonine/serine exporter
MALPKPHM_00752 1e-73 S Threonine/Serine exporter, ThrE
MALPKPHM_00753 1.3e-213 livJ E Receptor family ligand binding region
MALPKPHM_00754 2.5e-150 livH U Branched-chain amino acid transport system / permease component
MALPKPHM_00755 1.7e-120 livM E Branched-chain amino acid transport system / permease component
MALPKPHM_00756 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
MALPKPHM_00757 8.2e-123 livF E ABC transporter
MALPKPHM_00758 5.3e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
MALPKPHM_00759 1.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
MALPKPHM_00760 1e-232 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MALPKPHM_00761 4.3e-115 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MALPKPHM_00762 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MALPKPHM_00763 2.7e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MALPKPHM_00764 1.1e-145 p75 M NlpC P60 family protein
MALPKPHM_00765 1.8e-259 nox 1.6.3.4 C NADH oxidase
MALPKPHM_00766 4.4e-258 lacE-1 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
MALPKPHM_00767 1e-143 K CAT RNA binding domain
MALPKPHM_00768 5.2e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
MALPKPHM_00769 1.1e-235 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
MALPKPHM_00770 1.6e-157 sepS16B
MALPKPHM_00771 8.9e-119
MALPKPHM_00772 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
MALPKPHM_00773 9.6e-239 malE G Bacterial extracellular solute-binding protein
MALPKPHM_00774 3.7e-82
MALPKPHM_00775 3.7e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
MALPKPHM_00776 9e-130 XK27_08435 K UTRA
MALPKPHM_00777 5.9e-219 agaS G SIS domain
MALPKPHM_00778 4.1e-225 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MALPKPHM_00779 2.3e-124 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
MALPKPHM_00780 8.5e-226 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
MALPKPHM_00781 8.1e-82 manX_1 2.7.1.191 G PTS system sorbose subfamily IIB component
MALPKPHM_00782 1.5e-140 XK27_08455 G PTS system sorbose-specific iic component
MALPKPHM_00783 1.5e-144 manZ_1 G PTS system mannose/fructose/sorbose family IID component
MALPKPHM_00784 7.8e-64 XK27_08465 2.7.1.191 G PTS system fructose IIA component
MALPKPHM_00785 1e-173 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 F pfkB family carbohydrate kinase
MALPKPHM_00786 5.4e-147 IQ KR domain
MALPKPHM_00787 6.1e-244 gatC G PTS system sugar-specific permease component
MALPKPHM_00788 3.3e-86 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00789 1.5e-46 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_00790 2.8e-162
MALPKPHM_00791 7.2e-294 2.4.1.52 GT4 M Glycosyl transferases group 1
MALPKPHM_00792 0.0 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MALPKPHM_00793 7.5e-204 S Uncharacterized protein conserved in bacteria (DUF2325)
MALPKPHM_00794 3.1e-231 4.4.1.8 E Aminotransferase, class I
MALPKPHM_00795 5e-199 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MALPKPHM_00796 7.7e-252 2.7.1.207 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MALPKPHM_00797 1.8e-59 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_00798 1.5e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MALPKPHM_00799 9.2e-192 ypdE E M42 glutamyl aminopeptidase
MALPKPHM_00800 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00801 2.3e-237 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MALPKPHM_00802 3.2e-292 E ABC transporter, substratebinding protein
MALPKPHM_00803 4.5e-120 S Acetyltransferase (GNAT) family
MALPKPHM_00805 3e-125 nisT V ABC transporter
MALPKPHM_00806 3.4e-170 nisT V ABC transporter
MALPKPHM_00807 1.3e-94 S ABC-type cobalt transport system, permease component
MALPKPHM_00808 1.3e-243 P ABC transporter
MALPKPHM_00809 6.5e-111 P cobalt transport
MALPKPHM_00810 4.5e-126 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MALPKPHM_00811 1.9e-81 thiW S Thiamine-precursor transporter protein (ThiW)
MALPKPHM_00812 6e-149 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MALPKPHM_00813 1.4e-102 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MALPKPHM_00814 2.7e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MALPKPHM_00815 1.5e-272 E Amino acid permease
MALPKPHM_00816 1.7e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
MALPKPHM_00817 8.3e-61 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MALPKPHM_00818 1.7e-269 rbsA 3.6.3.17 G ABC transporter
MALPKPHM_00819 1e-152 rbsC U Belongs to the binding-protein-dependent transport system permease family
MALPKPHM_00820 8e-158 rbsB G Periplasmic binding protein domain
MALPKPHM_00821 9.6e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MALPKPHM_00822 2e-38 K DNA-binding helix-turn-helix protein
MALPKPHM_00823 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
MALPKPHM_00824 5e-53
MALPKPHM_00825 6.4e-87 V AAA domain, putative AbiEii toxin, Type IV TA system
MALPKPHM_00826 6.2e-78
MALPKPHM_00827 4.2e-60
MALPKPHM_00828 1.8e-91
MALPKPHM_00829 3e-238 ydiC1 EGP Major facilitator Superfamily
MALPKPHM_00830 2.1e-68 K helix_turn_helix multiple antibiotic resistance protein
MALPKPHM_00831 1.5e-103
MALPKPHM_00832 3.5e-29
MALPKPHM_00833 4.7e-36 K Helix-turn-helix XRE-family like proteins
MALPKPHM_00834 1e-165 GKT transcriptional antiterminator
MALPKPHM_00835 2.1e-46 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_00836 1.4e-205 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MALPKPHM_00837 5.1e-48
MALPKPHM_00838 1.2e-149 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MALPKPHM_00839 4.9e-87 6.3.4.4 S Zeta toxin
MALPKPHM_00840 7.3e-156 rihB 3.2.2.1 F Nucleoside
MALPKPHM_00841 4.9e-212 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
MALPKPHM_00842 5.3e-44 K Acetyltransferase (GNAT) family
MALPKPHM_00843 1.4e-117 K helix_turn_helix gluconate operon transcriptional repressor
MALPKPHM_00844 1.7e-89 4.1.2.13 G DeoC/LacD family aldolase
MALPKPHM_00845 1.7e-38 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MALPKPHM_00846 1.4e-180 2.7.1.53 G Belongs to the FGGY kinase family
MALPKPHM_00847 1.8e-91 IQ KR domain
MALPKPHM_00848 8.5e-126 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MALPKPHM_00849 2e-156 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
MALPKPHM_00850 1e-286 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00851 6.4e-154 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MALPKPHM_00852 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphotransferase system
MALPKPHM_00853 1.6e-238 sorE E Alcohol dehydrogenase GroES-like domain
MALPKPHM_00854 2.2e-163 sorC K sugar-binding domain protein
MALPKPHM_00855 4.1e-131 IQ NAD dependent epimerase/dehydratase family
MALPKPHM_00856 3.6e-62 sorF 2.7.1.191, 2.7.1.206 G PTS system fructose IIA component
MALPKPHM_00857 6.6e-79 sorB 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
MALPKPHM_00858 7.3e-131 sorA U PTS system sorbose-specific iic component
MALPKPHM_00859 1.2e-149 sorM G system, mannose fructose sorbose family IID component
MALPKPHM_00860 4.9e-149 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MALPKPHM_00861 1.1e-158 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
MALPKPHM_00862 3.5e-97 S UPF0397 protein
MALPKPHM_00863 0.0 3.6.3.24 P ATP-binding cassette cobalt transporter
MALPKPHM_00864 2.1e-146 cbiQ P cobalt transport
MALPKPHM_00865 1.3e-150 K Transcriptional regulator, LacI family
MALPKPHM_00866 4.7e-244 G Major Facilitator
MALPKPHM_00867 4.3e-292 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MALPKPHM_00868 2.2e-250 frdC 1.3.5.4 C HI0933-like protein
MALPKPHM_00869 9.9e-98 4.1.2.17 G Class II Aldolase and Adducin N-terminal domain
MALPKPHM_00871 4.8e-188 pts36C G iic component
MALPKPHM_00872 8.1e-09 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_00873 4.1e-30 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00874 5.9e-63 K DeoR C terminal sensor domain
MALPKPHM_00875 9.2e-56 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MALPKPHM_00876 3.7e-58 gntR K rpiR family
MALPKPHM_00877 3.3e-37 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00878 4e-168 S PTS system sugar-specific permease component
MALPKPHM_00879 1.9e-25 2.7.1.194 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MALPKPHM_00880 2.2e-132 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
MALPKPHM_00881 9.3e-67 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
MALPKPHM_00882 6.6e-219 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
MALPKPHM_00883 3.6e-210 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
MALPKPHM_00884 2.1e-37 glvR K Helix-turn-helix domain, rpiR family
MALPKPHM_00886 1.1e-18 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
MALPKPHM_00887 1.2e-43 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MALPKPHM_00888 4.2e-52 5.4.2.6 S Haloacid dehalogenase-like hydrolase
MALPKPHM_00889 2.5e-227 manR K PRD domain
MALPKPHM_00890 1.4e-27 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MALPKPHM_00891 2.7e-166 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MALPKPHM_00892 7.7e-61 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00893 4.7e-46 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_00894 9.4e-163 G Phosphotransferase System
MALPKPHM_00895 2.8e-126 G Domain of unknown function (DUF4432)
MALPKPHM_00896 2.8e-112 5.3.1.15 S Pfam:DUF1498
MALPKPHM_00897 6.7e-196 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MALPKPHM_00898 7.2e-61 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00899 9e-268 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_00900 3.9e-191 malY 4.4.1.8 E Aminotransferase class I and II
MALPKPHM_00901 2.2e-219 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00902 9.6e-64 kdsD 5.3.1.13 M SIS domain
MALPKPHM_00903 2.9e-44 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00904 3e-31 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_00905 2.5e-183 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MALPKPHM_00906 1.6e-86 4.3.3.7 E Dihydrodipicolinate synthetase family
MALPKPHM_00907 5.8e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MALPKPHM_00908 9e-197 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_00909 1.9e-18 hxlR K Transcriptional regulator, HxlR family
MALPKPHM_00910 3.3e-57 pnb C nitroreductase
MALPKPHM_00911 2.5e-119
MALPKPHM_00912 1.5e-07 K DNA-templated transcription, initiation
MALPKPHM_00913 1.3e-17 S YvrJ protein family
MALPKPHM_00914 4.3e-146 yqfZ 3.2.1.17 M hydrolase, family 25
MALPKPHM_00915 7.4e-86 ygfC K Bacterial regulatory proteins, tetR family
MALPKPHM_00916 7.2e-184 hrtB V ABC transporter permease
MALPKPHM_00917 2.1e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MALPKPHM_00918 3.8e-262 npr 1.11.1.1 C NADH oxidase
MALPKPHM_00919 9.1e-150 S hydrolase
MALPKPHM_00920 2.2e-44 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MALPKPHM_00921 6.2e-137 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
MALPKPHM_00924 3.5e-08
MALPKPHM_00925 5.3e-78 L Resolvase, N-terminal
MALPKPHM_00926 1.6e-202 tnpB L Putative transposase DNA-binding domain
MALPKPHM_00928 3e-148 metQ_4 P Belongs to the nlpA lipoprotein family
MALPKPHM_00929 1.1e-194 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MALPKPHM_00930 7.3e-175
MALPKPHM_00931 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
MALPKPHM_00932 9.4e-17
MALPKPHM_00933 1.8e-101 K Bacterial regulatory proteins, tetR family
MALPKPHM_00934 9.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
MALPKPHM_00935 5e-102 dhaL 2.7.1.121 S Dak2
MALPKPHM_00936 1e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MALPKPHM_00937 1.5e-76 ohr O OsmC-like protein
MALPKPHM_00939 4.7e-255 L Exonuclease
MALPKPHM_00940 5.3e-12 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MALPKPHM_00941 3.7e-31 relB L RelB antitoxin
MALPKPHM_00942 1.2e-48 K Helix-turn-helix domain
MALPKPHM_00943 1.4e-204 yceJ EGP Major facilitator Superfamily
MALPKPHM_00944 2.6e-141 stp_1 EGP Major Facilitator Superfamily
MALPKPHM_00945 1.9e-123 K helix_turn_helix, Arsenical Resistance Operon Repressor
MALPKPHM_00946 4.9e-60 K Transcriptional
MALPKPHM_00947 5.4e-101 tag 3.2.2.20 L glycosylase
MALPKPHM_00948 2e-32
MALPKPHM_00949 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MALPKPHM_00950 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MALPKPHM_00951 1e-44
MALPKPHM_00952 1.1e-152 V Beta-lactamase
MALPKPHM_00953 5.9e-194 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MALPKPHM_00954 7.8e-137 H Protein of unknown function (DUF1698)
MALPKPHM_00955 1.5e-139 puuD S peptidase C26
MALPKPHM_00956 1.3e-106 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
MALPKPHM_00957 2.3e-78 K Psort location Cytoplasmic, score
MALPKPHM_00958 4e-256 6.3.1.2 E Glutamine synthetase N-terminal domain
MALPKPHM_00959 3.2e-222 S Amidohydrolase
MALPKPHM_00960 1.2e-247 E Amino acid permease
MALPKPHM_00961 1.9e-74 K helix_turn_helix, mercury resistance
MALPKPHM_00962 3.7e-162 morA2 S reductase
MALPKPHM_00963 4.7e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MALPKPHM_00964 4e-59 hxlR K Transcriptional regulator, HxlR family
MALPKPHM_00965 1.5e-127 S membrane transporter protein
MALPKPHM_00966 5.9e-200
MALPKPHM_00967 1.2e-129 XK27_12140 V ATPases associated with a variety of cellular activities
MALPKPHM_00968 4.5e-294 S Psort location CytoplasmicMembrane, score
MALPKPHM_00969 7.5e-126 K Transcriptional regulatory protein, C terminal
MALPKPHM_00970 1.3e-196 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MALPKPHM_00971 2.2e-157 V ATPases associated with a variety of cellular activities
MALPKPHM_00972 2.2e-199
MALPKPHM_00973 8e-106
MALPKPHM_00974 1.7e-07
MALPKPHM_00975 0.0 pepN 3.4.11.2 E aminopeptidase
MALPKPHM_00976 9.3e-275 ycaM E amino acid
MALPKPHM_00977 1.4e-198 G MFS/sugar transport protein
MALPKPHM_00978 2.7e-13 G MFS/sugar transport protein
MALPKPHM_00979 7.6e-91 S Protein of unknown function (DUF1440)
MALPKPHM_00980 6.7e-161 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MALPKPHM_00981 2.7e-174 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MALPKPHM_00983 4.2e-141
MALPKPHM_00985 3e-212 metC 4.4.1.8 E cystathionine
MALPKPHM_00986 2.8e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MALPKPHM_00987 1.4e-119 tcyB E ABC transporter
MALPKPHM_00988 2.2e-117
MALPKPHM_00989 1.9e-253 brnQ U Component of the transport system for branched-chain amino acids
MALPKPHM_00990 1.1e-102 S WxL domain surface cell wall-binding
MALPKPHM_00991 1.7e-174 S Cell surface protein
MALPKPHM_00992 2.6e-45
MALPKPHM_00993 1.7e-189 XK27_00720 S Leucine-rich repeat (LRR) protein
MALPKPHM_00994 1.3e-168 yicL EG EamA-like transporter family
MALPKPHM_00995 2e-300
MALPKPHM_00996 4.7e-143 CcmA5 V ABC transporter
MALPKPHM_00997 1.4e-77 S ECF-type riboflavin transporter, S component
MALPKPHM_00998 1.2e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MALPKPHM_00999 1.8e-164 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
MALPKPHM_01000 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MALPKPHM_01001 0.0 XK27_09600 V ABC transporter, ATP-binding protein
MALPKPHM_01002 0.0 V ABC transporter
MALPKPHM_01003 4.7e-219 oxlT P Major Facilitator Superfamily
MALPKPHM_01004 3.2e-127 treR K UTRA
MALPKPHM_01005 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MALPKPHM_01006 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MALPKPHM_01007 6.9e-213 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MALPKPHM_01008 1.2e-269 yfnA E Amino Acid
MALPKPHM_01009 1.6e-171 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
MALPKPHM_01010 3.9e-251 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MALPKPHM_01011 4.6e-31 K 'Cold-shock' DNA-binding domain
MALPKPHM_01012 1.5e-66
MALPKPHM_01013 5.1e-75 O OsmC-like protein
MALPKPHM_01014 2.3e-281 lsa S ABC transporter
MALPKPHM_01015 1e-113 ylbE GM NAD(P)H-binding
MALPKPHM_01016 3.4e-160 yeaE S Aldo/keto reductase family
MALPKPHM_01017 2.1e-255 yifK E Amino acid permease
MALPKPHM_01018 1.3e-283 S Protein of unknown function (DUF3800)
MALPKPHM_01019 0.0 yjcE P Sodium proton antiporter
MALPKPHM_01020 2.2e-56 S Protein of unknown function (DUF3021)
MALPKPHM_01021 2.1e-68 K LytTr DNA-binding domain
MALPKPHM_01022 1.2e-147 cylB V ABC-2 type transporter
MALPKPHM_01023 5.7e-158 cylA V ABC transporter
MALPKPHM_01024 2.3e-134 S Alpha/beta hydrolase of unknown function (DUF915)
MALPKPHM_01025 1e-116 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
MALPKPHM_01026 2.6e-52 ybjQ S Belongs to the UPF0145 family
MALPKPHM_01027 1.4e-92 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
MALPKPHM_01028 4.5e-158 3.5.1.10 C nadph quinone reductase
MALPKPHM_01029 5.9e-244 amt P ammonium transporter
MALPKPHM_01030 1.5e-177 yfeX P Peroxidase
MALPKPHM_01031 1.5e-118 yhiD S MgtC family
MALPKPHM_01032 3e-145 F DNA RNA non-specific endonuclease
MALPKPHM_01034 3.9e-11
MALPKPHM_01035 2.3e-311 ybiT S ABC transporter, ATP-binding protein
MALPKPHM_01036 5.3e-274 mutS L ATPase domain of DNA mismatch repair MUTS family
MALPKPHM_01037 5.8e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
MALPKPHM_01038 1.9e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MALPKPHM_01039 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
MALPKPHM_01040 5.9e-296 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MALPKPHM_01041 3.1e-133 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
MALPKPHM_01043 6.5e-138 lacT K PRD domain
MALPKPHM_01044 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
MALPKPHM_01045 2.6e-245 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
MALPKPHM_01046 1.9e-50 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
MALPKPHM_01047 6.2e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MALPKPHM_01048 5.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MALPKPHM_01049 1.8e-281 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MALPKPHM_01050 6.2e-161 K Transcriptional regulator
MALPKPHM_01051 3.1e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MALPKPHM_01052 2.7e-10
MALPKPHM_01054 4.4e-83 agaB 2.7.1.191 G PTS system sorbose subfamily IIB component
MALPKPHM_01055 3.7e-124 agaC G PTS system sorbose-specific iic component
MALPKPHM_01056 6.8e-134 G PTS system mannose/fructose/sorbose family IID component
MALPKPHM_01057 5.5e-66 G PTS system fructose IIA component
MALPKPHM_01058 4.5e-61
MALPKPHM_01059 8.4e-97 S membrane transporter protein
MALPKPHM_01060 1.2e-156 V Beta-lactamase
MALPKPHM_01061 4e-111 S Domain of unknown function (DUF4867)
MALPKPHM_01062 1.1e-162 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
MALPKPHM_01063 1.8e-184 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
MALPKPHM_01064 9.9e-94 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
MALPKPHM_01065 6.1e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
MALPKPHM_01066 1.9e-141 lacR K DeoR C terminal sensor domain
MALPKPHM_01067 3.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MALPKPHM_01068 2.6e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MALPKPHM_01069 0.0 sbcC L Putative exonuclease SbcCD, C subunit
MALPKPHM_01070 1.3e-14
MALPKPHM_01071 3.1e-86 hsp1 O Belongs to the small heat shock protein (HSP20) family
MALPKPHM_01072 1.1e-210 mutY L A G-specific adenine glycosylase
MALPKPHM_01073 1.9e-149 cytC6 I alpha/beta hydrolase fold
MALPKPHM_01074 5.9e-121 yrkL S Flavodoxin-like fold
MALPKPHM_01076 8.2e-88 S Short repeat of unknown function (DUF308)
MALPKPHM_01077 3e-153 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MALPKPHM_01078 2.7e-199
MALPKPHM_01079 3.9e-07
MALPKPHM_01080 4e-116 ywnB S NmrA-like family
MALPKPHM_01081 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
MALPKPHM_01082 9.5e-167 XK27_00670 S ABC transporter substrate binding protein
MALPKPHM_01083 1.8e-165 XK27_00670 S ABC transporter
MALPKPHM_01084 2.9e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
MALPKPHM_01085 5.2e-142 cmpC S ABC transporter, ATP-binding protein
MALPKPHM_01086 1.4e-170 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
MALPKPHM_01087 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
MALPKPHM_01088 1.1e-181 ykcC GT2 M Glycosyl transferase family 2
MALPKPHM_01089 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
MALPKPHM_01090 3.2e-71 S GtrA-like protein
MALPKPHM_01091 1.3e-128 K cheY-homologous receiver domain
MALPKPHM_01092 3.9e-240 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MALPKPHM_01093 1.2e-67 yqkB S Belongs to the HesB IscA family
MALPKPHM_01094 4.9e-122 drgA C Nitroreductase family
MALPKPHM_01095 1e-204 lctO C IMP dehydrogenase / GMP reductase domain
MALPKPHM_01098 1.2e-180 K sequence-specific DNA binding
MALPKPHM_01099 3.1e-56 K Transcriptional regulator PadR-like family
MALPKPHM_01100 4e-42 ygbF S Sugar efflux transporter for intercellular exchange
MALPKPHM_01101 6.6e-50
MALPKPHM_01102 2e-183 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MALPKPHM_01103 9.8e-56
MALPKPHM_01104 3.4e-80
MALPKPHM_01105 2.3e-207 yubA S AI-2E family transporter
MALPKPHM_01106 7.4e-26
MALPKPHM_01107 1e-97 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MALPKPHM_01108 8.8e-73
MALPKPHM_01109 2.9e-168 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MALPKPHM_01110 7.9e-106 ywrF S Flavin reductase like domain
MALPKPHM_01111 1.5e-95
MALPKPHM_01112 5.2e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MALPKPHM_01113 3.3e-61 yeaO S Protein of unknown function, DUF488
MALPKPHM_01114 8.6e-173 corA P CorA-like Mg2+ transporter protein
MALPKPHM_01115 2.1e-160 mleR K LysR family
MALPKPHM_01116 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MALPKPHM_01117 1.1e-170 mleP S Sodium Bile acid symporter family
MALPKPHM_01118 5.9e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MALPKPHM_01119 3.1e-95
MALPKPHM_01120 2.6e-172 K sequence-specific DNA binding
MALPKPHM_01121 2.9e-285 V ABC transporter transmembrane region
MALPKPHM_01122 0.0 pepF E Oligopeptidase F
MALPKPHM_01123 2.5e-77 ndk 2.7.4.6 F Belongs to the NDK family
MALPKPHM_01124 1.1e-59
MALPKPHM_01125 0.0 yfgQ P E1-E2 ATPase
MALPKPHM_01126 4.8e-176 3.4.11.5 I Releases the N-terminal proline from various substrates
MALPKPHM_01127 1.8e-59
MALPKPHM_01128 3.7e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MALPKPHM_01129 1.1e-193 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MALPKPHM_01130 1e-119 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
MALPKPHM_01131 3.3e-77 K Transcriptional regulator
MALPKPHM_01132 8e-179 D Alpha beta
MALPKPHM_01133 2.9e-84 nrdI F Belongs to the NrdI family
MALPKPHM_01134 1.5e-157 dkgB S reductase
MALPKPHM_01135 2e-119
MALPKPHM_01136 6.2e-162 S Alpha beta hydrolase
MALPKPHM_01137 1e-116 yviA S Protein of unknown function (DUF421)
MALPKPHM_01138 3.5e-74 S Protein of unknown function (DUF3290)
MALPKPHM_01139 5.5e-222 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
MALPKPHM_01140 1.6e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MALPKPHM_01141 4.6e-103 yjbF S SNARE associated Golgi protein
MALPKPHM_01142 8.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MALPKPHM_01143 1.1e-195 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MALPKPHM_01144 9.5e-208 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MALPKPHM_01145 1.5e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MALPKPHM_01146 2.2e-38 yajC U Preprotein translocase
MALPKPHM_01147 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MALPKPHM_01148 3.9e-116 sirR K Helix-turn-helix diphteria tox regulatory element
MALPKPHM_01149 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MALPKPHM_01150 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MALPKPHM_01151 1.5e-239 ytoI K DRTGG domain
MALPKPHM_01152 1e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MALPKPHM_01153 5.6e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MALPKPHM_01154 1.8e-170
MALPKPHM_01155 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MALPKPHM_01156 2.6e-208
MALPKPHM_01157 4e-43 yrzL S Belongs to the UPF0297 family
MALPKPHM_01158 9.5e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MALPKPHM_01159 2.3e-53 yrzB S Belongs to the UPF0473 family
MALPKPHM_01160 2e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MALPKPHM_01161 2.5e-92 cvpA S Colicin V production protein
MALPKPHM_01162 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MALPKPHM_01163 6.6e-53 trxA O Belongs to the thioredoxin family
MALPKPHM_01164 1.4e-292 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MALPKPHM_01165 1.8e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
MALPKPHM_01166 4e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MALPKPHM_01167 1.2e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MALPKPHM_01168 8.1e-82 yslB S Protein of unknown function (DUF2507)
MALPKPHM_01169 5.3e-278 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MALPKPHM_01170 9e-95 S Phosphoesterase
MALPKPHM_01171 8.9e-133 gla U Major intrinsic protein
MALPKPHM_01172 3e-84 ykuL S CBS domain
MALPKPHM_01173 1.1e-156 XK27_00890 S Domain of unknown function (DUF368)
MALPKPHM_01174 1.8e-156 ykuT M mechanosensitive ion channel
MALPKPHM_01176 1.9e-78 ytxH S YtxH-like protein
MALPKPHM_01177 5e-93 niaR S 3H domain
MALPKPHM_01178 2.6e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MALPKPHM_01179 2.3e-179 ccpA K catabolite control protein A
MALPKPHM_01180 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
MALPKPHM_01181 1.8e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
MALPKPHM_01182 3.4e-135 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MALPKPHM_01183 7.1e-272 pepV 3.5.1.18 E dipeptidase PepV
MALPKPHM_01184 8.9e-256 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MALPKPHM_01185 2.1e-54
MALPKPHM_01186 2.9e-188 yibE S overlaps another CDS with the same product name
MALPKPHM_01187 1.3e-115 yibF S overlaps another CDS with the same product name
MALPKPHM_01188 1.8e-115 S Calcineurin-like phosphoesterase
MALPKPHM_01189 5.7e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MALPKPHM_01190 1e-110 yutD S Protein of unknown function (DUF1027)
MALPKPHM_01191 1.7e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MALPKPHM_01192 4e-105 S Protein of unknown function (DUF1461)
MALPKPHM_01193 8.9e-116 dedA S SNARE-like domain protein
MALPKPHM_01194 1.5e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MALPKPHM_01195 7.4e-183 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MALPKPHM_01196 1.7e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MALPKPHM_01197 4.3e-64 yugI 5.3.1.9 J general stress protein
MALPKPHM_01198 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MALPKPHM_01199 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MALPKPHM_01200 8.5e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MALPKPHM_01201 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MALPKPHM_01202 5.9e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MALPKPHM_01203 2.7e-241 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MALPKPHM_01204 6.1e-82 yabR J RNA binding
MALPKPHM_01205 4.4e-65 divIC D cell cycle
MALPKPHM_01206 1.8e-38 yabO J S4 domain protein
MALPKPHM_01207 1.6e-280 yabM S Polysaccharide biosynthesis protein
MALPKPHM_01208 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MALPKPHM_01209 9e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MALPKPHM_01210 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MALPKPHM_01211 1e-262 S Putative peptidoglycan binding domain
MALPKPHM_01212 1.3e-96 padR K Transcriptional regulator PadR-like family
MALPKPHM_01213 4.1e-238 XK27_06930 S ABC-2 family transporter protein
MALPKPHM_01214 3.4e-114 1.6.5.2 S Flavodoxin-like fold
MALPKPHM_01215 1.5e-118 S (CBS) domain
MALPKPHM_01216 1.3e-128 yciB M ErfK YbiS YcfS YnhG
MALPKPHM_01217 2.1e-279 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MALPKPHM_01218 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
MALPKPHM_01219 1.8e-87 S QueT transporter
MALPKPHM_01220 1.6e-61 ndoA L Toxic component of a toxin-antitoxin (TA) module
MALPKPHM_01221 2.4e-37
MALPKPHM_01222 7e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MALPKPHM_01223 1.7e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MALPKPHM_01224 4.5e-264 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MALPKPHM_01225 2.8e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MALPKPHM_01226 1.6e-145
MALPKPHM_01227 6.6e-124 S Tetratricopeptide repeat
MALPKPHM_01228 1.1e-121
MALPKPHM_01229 1.4e-72
MALPKPHM_01230 3.3e-42 rpmE2 J Ribosomal protein L31
MALPKPHM_01231 2.8e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MALPKPHM_01232 7.2e-275 L PFAM Integrase core domain
MALPKPHM_01236 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MALPKPHM_01237 7e-220 ndh 1.6.99.3 C NADH dehydrogenase
MALPKPHM_01240 3.5e-152 S Protein of unknown function (DUF1211)
MALPKPHM_01241 5.9e-62 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MALPKPHM_01242 5.9e-79 ywiB S Domain of unknown function (DUF1934)
MALPKPHM_01243 1.5e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
MALPKPHM_01244 2.8e-265 ywfO S HD domain protein
MALPKPHM_01245 6.8e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
MALPKPHM_01246 1.3e-97 S DUF218 domain
MALPKPHM_01247 2.7e-42 S DUF218 domain
MALPKPHM_01248 1.8e-60 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MALPKPHM_01249 1.4e-72
MALPKPHM_01250 2.3e-51 nudA S ASCH
MALPKPHM_01251 1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MALPKPHM_01252 5.1e-214 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MALPKPHM_01253 5.4e-220 ysaA V RDD family
MALPKPHM_01254 6.5e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MALPKPHM_01255 6.5e-119 ybbL S ABC transporter, ATP-binding protein
MALPKPHM_01256 1.8e-123 ybbM S Uncharacterised protein family (UPF0014)
MALPKPHM_01257 6.7e-159 czcD P cation diffusion facilitator family transporter
MALPKPHM_01258 2.6e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MALPKPHM_01259 1.1e-37 veg S Biofilm formation stimulator VEG
MALPKPHM_01260 1.4e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MALPKPHM_01261 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MALPKPHM_01262 1.4e-147 tatD L hydrolase, TatD family
MALPKPHM_01263 4.5e-80 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MALPKPHM_01264 9.5e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
MALPKPHM_01265 7.6e-171 yqhA G Aldose 1-epimerase
MALPKPHM_01266 3.3e-124 T LytTr DNA-binding domain
MALPKPHM_01267 8.2e-168 2.7.13.3 T GHKL domain
MALPKPHM_01268 0.0 V ABC transporter
MALPKPHM_01269 0.0 V ABC transporter
MALPKPHM_01270 1.1e-30 K Transcriptional
MALPKPHM_01271 2.2e-65
MALPKPHM_01272 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MALPKPHM_01273 1.4e-173 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
MALPKPHM_01274 1.1e-147 yunF F Protein of unknown function DUF72
MALPKPHM_01275 1.9e-91 3.6.1.55 F NUDIX domain
MALPKPHM_01276 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MALPKPHM_01277 1.4e-107 yiiE S Protein of unknown function (DUF1211)
MALPKPHM_01278 2.2e-128 cobB K Sir2 family
MALPKPHM_01279 2.8e-17
MALPKPHM_01280 2e-169
MALPKPHM_01281 2.5e-97 yxkA S Phosphatidylethanolamine-binding protein
MALPKPHM_01283 3.2e-162 ypuA S Protein of unknown function (DUF1002)
MALPKPHM_01284 9.6e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MALPKPHM_01285 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MALPKPHM_01286 2.8e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MALPKPHM_01287 3e-173 S Aldo keto reductase
MALPKPHM_01288 9.3e-155 bioC 2.1.1.187, 2.1.1.197 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
MALPKPHM_01289 8.8e-92 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MALPKPHM_01290 1e-238 dinF V MatE
MALPKPHM_01291 1.2e-109 S TPM domain
MALPKPHM_01292 3e-102 lemA S LemA family
MALPKPHM_01293 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MALPKPHM_01294 4.1e-67
MALPKPHM_01295 2.9e-24
MALPKPHM_01296 2.2e-38
MALPKPHM_01297 4.8e-117 V ATPases associated with a variety of cellular activities
MALPKPHM_01298 7e-19
MALPKPHM_01299 1.3e-251 gshR 1.8.1.7 C Glutathione reductase
MALPKPHM_01300 3.3e-175 proV E ABC transporter, ATP-binding protein
MALPKPHM_01301 3.7e-274 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MALPKPHM_01302 0.0 helD 3.6.4.12 L DNA helicase
MALPKPHM_01303 2.9e-148 rlrG K Transcriptional regulator
MALPKPHM_01304 1.3e-174 shetA P Voltage-dependent anion channel
MALPKPHM_01305 2.3e-108 S CAAX protease self-immunity
MALPKPHM_01307 9.9e-278 V ABC transporter transmembrane region
MALPKPHM_01308 8.8e-108 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MALPKPHM_01309 7.2e-71 K MarR family
MALPKPHM_01310 0.0 uvrA3 L excinuclease ABC
MALPKPHM_01311 1.5e-191 yghZ C Aldo keto reductase family protein
MALPKPHM_01312 1.4e-142 S hydrolase
MALPKPHM_01313 1.2e-58
MALPKPHM_01314 4.8e-12
MALPKPHM_01315 3.9e-42
MALPKPHM_01316 1.5e-27
MALPKPHM_01318 3e-62 V ABC transporter
MALPKPHM_01320 8.5e-117 yoaK S Protein of unknown function (DUF1275)
MALPKPHM_01321 1.5e-126 yjhF G Phosphoglycerate mutase family
MALPKPHM_01322 1.4e-150 yitU 3.1.3.104 S hydrolase
MALPKPHM_01323 3.6e-90 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MALPKPHM_01324 5.8e-166 K LysR substrate binding domain
MALPKPHM_01325 6e-227 EK Aminotransferase, class I
MALPKPHM_01326 1e-45
MALPKPHM_01327 9.4e-58
MALPKPHM_01328 5.6e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MALPKPHM_01329 7.3e-116 ydfK S Protein of unknown function (DUF554)
MALPKPHM_01330 4.3e-88
MALPKPHM_01331 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_01332 6.4e-168 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
MALPKPHM_01333 1.1e-130 rpl K Helix-turn-helix domain, rpiR family
MALPKPHM_01334 1.6e-296 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MALPKPHM_01335 6.9e-90 L Helix-turn-helix domain
MALPKPHM_01336 1.8e-147 L PFAM Integrase catalytic region
MALPKPHM_01337 4e-289 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MALPKPHM_01338 3.2e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MALPKPHM_01339 2.1e-244 P Sodium:sulfate symporter transmembrane region
MALPKPHM_01340 5.8e-158 K LysR substrate binding domain
MALPKPHM_01341 1.2e-76
MALPKPHM_01342 1.8e-72 K Transcriptional regulator
MALPKPHM_01343 3.3e-18 ypiB EGP Major facilitator Superfamily
MALPKPHM_01344 3.2e-212 ypiB EGP Major facilitator Superfamily
MALPKPHM_01345 7.8e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
MALPKPHM_01347 5.6e-241 pts36C G PTS system sugar-specific permease component
MALPKPHM_01348 1.1e-50 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_01349 3e-68 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_01350 6.1e-119 K DeoR C terminal sensor domain
MALPKPHM_01351 1.8e-167 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MALPKPHM_01352 5.4e-258 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
MALPKPHM_01353 3.8e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MALPKPHM_01354 4.7e-282 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MALPKPHM_01355 1.1e-226 iolF EGP Major facilitator Superfamily
MALPKPHM_01356 4.1e-192 rhaR K helix_turn_helix, arabinose operon control protein
MALPKPHM_01357 1.2e-213 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MALPKPHM_01358 5.4e-65 S Protein of unknown function (DUF1093)
MALPKPHM_01359 5e-96
MALPKPHM_01360 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MALPKPHM_01361 1.9e-303 plyA3 M Right handed beta helix region
MALPKPHM_01362 5.5e-80
MALPKPHM_01363 7.8e-269 M Heparinase II/III N-terminus
MALPKPHM_01365 3.5e-66 G PTS system fructose IIA component
MALPKPHM_01366 3.6e-143 agaD G PTS system mannose/fructose/sorbose family IID component
MALPKPHM_01367 6.4e-132 G PTS system sorbose-specific iic component
MALPKPHM_01368 5.4e-81 agaV 2.7.1.191 G PTS system sorbose subfamily IIB component
MALPKPHM_01369 6.3e-205 ugl 3.2.1.180 GH88 S Glycosyl Hydrolase Family 88
MALPKPHM_01370 1.6e-101 Z012_03480 S Psort location Cytoplasmic, score
MALPKPHM_01371 1.6e-108 K Bacterial transcriptional regulator
MALPKPHM_01372 5.8e-144 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MALPKPHM_01373 1e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MALPKPHM_01374 6e-88 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MALPKPHM_01375 2.4e-152 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
MALPKPHM_01376 5.1e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MALPKPHM_01378 0.0 CP_0954 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
MALPKPHM_01379 5.5e-207 rafA 3.2.1.22 G Melibiase
MALPKPHM_01380 5e-39 2.7.1.191 G PTS system sorbose subfamily IIB component
MALPKPHM_01381 3.1e-65 G PTS system mannose/fructose/sorbose family IID component
MALPKPHM_01382 4.4e-64 G PTS system sorbose-specific iic component
MALPKPHM_01383 2.1e-22 2.7.1.191 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MALPKPHM_01384 4.6e-53 araR K Transcriptional regulator
MALPKPHM_01385 3.9e-270 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
MALPKPHM_01386 1.5e-294 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
MALPKPHM_01388 9.2e-125 K Helix-turn-helix domain, rpiR family
MALPKPHM_01389 2.8e-82 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MALPKPHM_01390 6.2e-137 4.1.2.14 S KDGP aldolase
MALPKPHM_01391 5e-204 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
MALPKPHM_01392 3.8e-215 dho 3.5.2.3 S Amidohydrolase family
MALPKPHM_01393 3.6e-107 S Domain of unknown function (DUF4310)
MALPKPHM_01394 1.7e-137 S Domain of unknown function (DUF4311)
MALPKPHM_01395 6e-53 S Domain of unknown function (DUF4312)
MALPKPHM_01396 1.2e-61 S Glycine-rich SFCGS
MALPKPHM_01397 4e-54 S PRD domain
MALPKPHM_01398 0.0 K Mga helix-turn-helix domain
MALPKPHM_01399 6.5e-122 tal 2.2.1.2 H Pfam:Transaldolase
MALPKPHM_01400 3.9e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MALPKPHM_01401 1.3e-194 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
MALPKPHM_01402 2.2e-102 srlA G PTS system enzyme II sorbitol-specific factor
MALPKPHM_01403 2.7e-88 gutM K Glucitol operon activator protein (GutM)
MALPKPHM_01404 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
MALPKPHM_01405 8.5e-145 IQ NAD dependent epimerase/dehydratase family
MALPKPHM_01406 1.3e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MALPKPHM_01407 1.5e-149 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
MALPKPHM_01408 7.9e-168 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
MALPKPHM_01409 1.3e-137 repA K DeoR C terminal sensor domain
MALPKPHM_01410 1.3e-114 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
MALPKPHM_01411 3.7e-45 sgaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_01412 5.3e-281 ulaA S PTS system sugar-specific permease component
MALPKPHM_01413 1.1e-80 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MALPKPHM_01414 3.4e-213 ulaG S Beta-lactamase superfamily domain
MALPKPHM_01415 0.0 O Belongs to the peptidase S8 family
MALPKPHM_01416 1.3e-41
MALPKPHM_01417 7e-156 bglK_1 GK ROK family
MALPKPHM_01418 4.4e-180 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
MALPKPHM_01419 1e-248 3.5.1.18 E Peptidase family M20/M25/M40
MALPKPHM_01420 4.1e-130 ymfC K UTRA
MALPKPHM_01421 9e-215 uhpT EGP Major facilitator Superfamily
MALPKPHM_01422 3.5e-207 3.2.1.51 GH29 G Alpha-L-fucosidase
MALPKPHM_01423 1.5e-153 GM NAD dependent epimerase/dehydratase family
MALPKPHM_01424 2.5e-113 hchA S DJ-1/PfpI family
MALPKPHM_01425 7.8e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
MALPKPHM_01426 3.1e-92 yjgM K Acetyltransferase (GNAT) domain
MALPKPHM_01427 2.4e-110 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
MALPKPHM_01428 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
MALPKPHM_01429 3.3e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
MALPKPHM_01430 4.5e-108 pncA Q Isochorismatase family
MALPKPHM_01431 5.1e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MALPKPHM_01432 1.2e-131 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MALPKPHM_01433 9.3e-71 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MALPKPHM_01434 6.4e-241 ugpB G Bacterial extracellular solute-binding protein
MALPKPHM_01435 2.2e-148 ugpE G ABC transporter permease
MALPKPHM_01436 2.8e-163 ugpA P ABC-type sugar transport systems, permease components
MALPKPHM_01437 1.4e-209 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
MALPKPHM_01438 5.4e-226 EGP Major facilitator Superfamily
MALPKPHM_01439 4e-147 3.5.2.6 V Beta-lactamase enzyme family
MALPKPHM_01440 2.2e-190 blaA6 V Beta-lactamase
MALPKPHM_01441 2e-147 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MALPKPHM_01442 3.7e-163 ybbH_2 K Helix-turn-helix domain, rpiR family
MALPKPHM_01443 7.6e-80 2.7.1.191 G PTS system sorbose subfamily IIB component
MALPKPHM_01444 2.4e-150 G PTS system mannose/fructose/sorbose family IID component
MALPKPHM_01445 8.9e-129 G PTS system sorbose-specific iic component
MALPKPHM_01447 1e-201 S endonuclease exonuclease phosphatase family protein
MALPKPHM_01448 9.9e-169 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MALPKPHM_01449 7.4e-143 Q Methyltransferase
MALPKPHM_01450 1.7e-51 sugE U Multidrug resistance protein
MALPKPHM_01452 6.5e-141 V ABC transporter transmembrane region
MALPKPHM_01453 3.8e-59
MALPKPHM_01454 1.5e-36
MALPKPHM_01455 2.9e-108 S alpha beta
MALPKPHM_01456 5e-87 MA20_25245 K FR47-like protein
MALPKPHM_01457 7.7e-132 wzb 3.1.3.48 T Tyrosine phosphatase family
MALPKPHM_01458 6.6e-84 K Acetyltransferase (GNAT) domain
MALPKPHM_01459 5.3e-124
MALPKPHM_01460 9.5e-69 6.3.3.2 S ASCH
MALPKPHM_01461 1.4e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MALPKPHM_01462 4.1e-198 ybiR P Citrate transporter
MALPKPHM_01463 5.6e-102
MALPKPHM_01464 2.3e-256 E Peptidase dimerisation domain
MALPKPHM_01465 1.1e-295 E ABC transporter, substratebinding protein
MALPKPHM_01466 7.3e-140
MALPKPHM_01467 7.4e-44 cadA P P-type ATPase
MALPKPHM_01468 1.8e-268 cadA P P-type ATPase
MALPKPHM_01469 1.4e-75 hsp3 O Hsp20/alpha crystallin family
MALPKPHM_01470 5.9e-70 S Iron-sulphur cluster biosynthesis
MALPKPHM_01471 5e-206 htrA 3.4.21.107 O serine protease
MALPKPHM_01473 2.7e-154 vicX 3.1.26.11 S domain protein
MALPKPHM_01474 7.4e-141 yycI S YycH protein
MALPKPHM_01475 5.3e-259 yycH S YycH protein
MALPKPHM_01476 0.0 vicK 2.7.13.3 T Histidine kinase
MALPKPHM_01477 8.1e-131 K response regulator
MALPKPHM_01478 3.2e-121 S Alpha/beta hydrolase family
MALPKPHM_01479 9.3e-259 arpJ P ABC transporter permease
MALPKPHM_01480 7.4e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MALPKPHM_01481 1.2e-266 argH 4.3.2.1 E argininosuccinate lyase
MALPKPHM_01482 3.5e-213 S Bacterial protein of unknown function (DUF871)
MALPKPHM_01483 1.2e-73 S Domain of unknown function (DUF3284)
MALPKPHM_01484 4.9e-233 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MALPKPHM_01485 6.9e-130 K UbiC transcription regulator-associated domain protein
MALPKPHM_01486 3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_01487 4.9e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MALPKPHM_01488 4.9e-107 speG J Acetyltransferase (GNAT) domain
MALPKPHM_01489 1.2e-80 F NUDIX domain
MALPKPHM_01490 1e-90 S AAA domain
MALPKPHM_01491 2.3e-113 ycaC Q Isochorismatase family
MALPKPHM_01492 3.1e-191 ydiC1 EGP Major Facilitator Superfamily
MALPKPHM_01493 1.3e-42 ydiC1 EGP Major Facilitator Superfamily
MALPKPHM_01494 8.3e-213 yeaN P Transporter, major facilitator family protein
MALPKPHM_01495 5e-173 iolS C Aldo keto reductase
MALPKPHM_01496 5.8e-64 manO S Domain of unknown function (DUF956)
MALPKPHM_01497 8.7e-170 manN G system, mannose fructose sorbose family IID component
MALPKPHM_01498 1.6e-122 manY G PTS system
MALPKPHM_01499 1.3e-182 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MALPKPHM_01500 8.9e-221 EGP Major facilitator Superfamily
MALPKPHM_01501 6.7e-187 K Helix-turn-helix XRE-family like proteins
MALPKPHM_01502 1.9e-150 K Helix-turn-helix XRE-family like proteins
MALPKPHM_01503 1.4e-156 K sequence-specific DNA binding
MALPKPHM_01507 0.0 ybfG M peptidoglycan-binding domain-containing protein
MALPKPHM_01508 4e-287 glnP P ABC transporter permease
MALPKPHM_01509 4.1e-133 glnQ E ABC transporter, ATP-binding protein
MALPKPHM_01510 3.7e-39
MALPKPHM_01511 7.5e-236 malE G Bacterial extracellular solute-binding protein
MALPKPHM_01512 6.9e-130 S Protein of unknown function (DUF975)
MALPKPHM_01513 1.5e-58 yqkB S Iron-sulphur cluster biosynthesis
MALPKPHM_01514 1.2e-52
MALPKPHM_01515 1.9e-80 S Bacterial PH domain
MALPKPHM_01516 3.8e-279 ydbT S Bacterial PH domain
MALPKPHM_01517 1.4e-144 S AAA ATPase domain
MALPKPHM_01518 1.1e-166 yniA G Phosphotransferase enzyme family
MALPKPHM_01519 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MALPKPHM_01520 3.2e-256 glnP P ABC transporter
MALPKPHM_01521 7.4e-264 glnP P ABC transporter
MALPKPHM_01522 8.3e-99 ydaF J Acetyltransferase (GNAT) domain
MALPKPHM_01523 3.7e-103 S Stage II sporulation protein M
MALPKPHM_01524 2.3e-165 yeaC S ATPase family associated with various cellular activities (AAA)
MALPKPHM_01525 1.1e-130 yeaD S Protein of unknown function DUF58
MALPKPHM_01526 0.0 yebA E Transglutaminase/protease-like homologues
MALPKPHM_01527 9.2e-214 lsgC M Glycosyl transferases group 1
MALPKPHM_01528 8.7e-254 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
MALPKPHM_01529 6.9e-112 S Bacteriocin-protection, YdeI or OmpD-Associated
MALPKPHM_01530 1.1e-55 yjdF S Protein of unknown function (DUF2992)
MALPKPHM_01533 7.5e-198 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
MALPKPHM_01534 2.2e-222 maeN C 2-hydroxycarboxylate transporter family
MALPKPHM_01535 2e-267 dcuS 2.7.13.3 T Single cache domain 3
MALPKPHM_01536 1.1e-119 dpiA KT cheY-homologous receiver domain
MALPKPHM_01537 1.4e-98
MALPKPHM_01538 5.1e-17 hprA 1.1.1.29 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MALPKPHM_01539 2.7e-149 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
MALPKPHM_01540 1.4e-68
MALPKPHM_01541 1.6e-131 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
MALPKPHM_01542 5.8e-169 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MALPKPHM_01543 2.5e-227 ptsG G phosphotransferase system
MALPKPHM_01544 1.8e-100 K CAT RNA binding domain
MALPKPHM_01546 8.8e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MALPKPHM_01547 1.5e-180 D Alpha beta
MALPKPHM_01548 5.9e-185 lipA I Carboxylesterase family
MALPKPHM_01549 3.5e-216 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MALPKPHM_01550 1e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MALPKPHM_01551 0.0 mtlR K Mga helix-turn-helix domain
MALPKPHM_01552 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MALPKPHM_01553 2.8e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MALPKPHM_01554 9.5e-149 S haloacid dehalogenase-like hydrolase
MALPKPHM_01555 2.8e-44
MALPKPHM_01556 2e-14
MALPKPHM_01557 7e-136
MALPKPHM_01558 2e-219 spiA K IrrE N-terminal-like domain
MALPKPHM_01559 2.8e-151 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MALPKPHM_01560 2e-126 V ABC transporter
MALPKPHM_01561 4.7e-208 bacI V MacB-like periplasmic core domain
MALPKPHM_01562 4.8e-179
MALPKPHM_01563 0.0 M Leucine rich repeats (6 copies)
MALPKPHM_01564 7.9e-224 mtnE 2.6.1.83 E Aminotransferase
MALPKPHM_01565 1.7e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MALPKPHM_01566 1.2e-149 M NLPA lipoprotein
MALPKPHM_01569 2.4e-198 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
MALPKPHM_01570 2.4e-223 amd 3.5.1.47 E Peptidase family M20/M25/M40
MALPKPHM_01571 2.6e-80 S Threonine/Serine exporter, ThrE
MALPKPHM_01572 4.6e-132 thrE S Putative threonine/serine exporter
MALPKPHM_01574 1.1e-30
MALPKPHM_01575 3.7e-272 V ABC transporter transmembrane region
MALPKPHM_01576 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MALPKPHM_01577 4e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MALPKPHM_01578 1.3e-137 jag S R3H domain protein
MALPKPHM_01579 6.4e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MALPKPHM_01580 1.9e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MALPKPHM_01581 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MALPKPHM_01582 7.9e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MALPKPHM_01583 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MALPKPHM_01584 2.9e-31 yaaA S S4 domain protein YaaA
MALPKPHM_01585 1.3e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MALPKPHM_01586 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MALPKPHM_01587 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MALPKPHM_01588 7.6e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MALPKPHM_01589 2.7e-73 ssb_2 L Single-strand binding protein family
MALPKPHM_01590 2.7e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MALPKPHM_01591 1.1e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MALPKPHM_01592 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MALPKPHM_01593 1.5e-91 yhbO 3.5.1.124 S DJ-1/PfpI family
MALPKPHM_01594 1.2e-280 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
MALPKPHM_01595 9.4e-181 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
MALPKPHM_01596 2.1e-28
MALPKPHM_01597 2.9e-85 S CAAX protease self-immunity
MALPKPHM_01598 9.8e-121 S CAAX protease self-immunity
MALPKPHM_01599 6e-84 V Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
MALPKPHM_01600 1.6e-160 V ABC transporter
MALPKPHM_01601 8.2e-191 amtB P Ammonium Transporter Family
MALPKPHM_01602 8.9e-209 P Pyridine nucleotide-disulphide oxidoreductase
MALPKPHM_01603 4e-125 usp 3.5.1.28 CBM50 D CHAP domain
MALPKPHM_01604 0.0 ylbB V ABC transporter permease
MALPKPHM_01605 2.4e-127 macB V ABC transporter, ATP-binding protein
MALPKPHM_01606 2.8e-94 K transcriptional regulator
MALPKPHM_01607 2.9e-153 supH G Sucrose-6F-phosphate phosphohydrolase
MALPKPHM_01608 4.1e-128 S membrane transporter protein
MALPKPHM_01609 2.7e-103 S Protein of unknown function (DUF1211)
MALPKPHM_01610 5e-113 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MALPKPHM_01611 6.5e-54
MALPKPHM_01612 8.1e-287 pipD E Dipeptidase
MALPKPHM_01613 2.3e-105 S Membrane
MALPKPHM_01614 1.9e-84
MALPKPHM_01615 2.2e-52
MALPKPHM_01616 4.9e-52
MALPKPHM_01617 9e-179 ybfG M peptidoglycan-binding domain-containing protein
MALPKPHM_01618 2.4e-122 azlC E branched-chain amino acid
MALPKPHM_01619 1.5e-50 azlD S Branched-chain amino acid transport protein (AzlD)
MALPKPHM_01620 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
MALPKPHM_01621 0.0 M Glycosyl hydrolase family 59
MALPKPHM_01622 1.4e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MALPKPHM_01623 7.8e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
MALPKPHM_01624 1.2e-279 uxaC 5.3.1.12 G glucuronate isomerase
MALPKPHM_01625 1.7e-217 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MALPKPHM_01626 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
MALPKPHM_01627 7.8e-267 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
MALPKPHM_01628 5.6e-245 G Major Facilitator
MALPKPHM_01629 1.2e-126 kdgR K FCD domain
MALPKPHM_01630 1.5e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
MALPKPHM_01631 0.0 M Glycosyl hydrolase family 59
MALPKPHM_01632 5.6e-58
MALPKPHM_01633 1e-64 S pyridoxamine 5-phosphate
MALPKPHM_01634 2.6e-242 EGP Major facilitator Superfamily
MALPKPHM_01636 0.0 ydgH S MMPL family
MALPKPHM_01637 2e-106 K Tetracycline repressor, C-terminal all-alpha domain
MALPKPHM_01638 9.7e-122 S Sulfite exporter TauE/SafE
MALPKPHM_01639 1.3e-246 3.5.4.28, 3.5.4.31 F Amidohydrolase family
MALPKPHM_01640 3.3e-69 S An automated process has identified a potential problem with this gene model
MALPKPHM_01641 1e-148 S Protein of unknown function (DUF3100)
MALPKPHM_01643 1.9e-110 opuCD P Binding-protein-dependent transport system inner membrane component
MALPKPHM_01644 7.8e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MALPKPHM_01645 4.7e-106 opuCB E ABC transporter permease
MALPKPHM_01646 1.6e-214 opuCA E ABC transporter, ATP-binding protein
MALPKPHM_01647 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
MALPKPHM_01648 6.2e-32 copZ P Heavy-metal-associated domain
MALPKPHM_01649 1.2e-100 dps P Belongs to the Dps family
MALPKPHM_01650 6.8e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MALPKPHM_01651 1.3e-96 K Bacterial regulatory proteins, tetR family
MALPKPHM_01652 1.6e-83 S Protein of unknown function with HXXEE motif
MALPKPHM_01654 1e-159 S CAAX protease self-immunity
MALPKPHM_01656 2.5e-136 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MALPKPHM_01657 1.4e-228 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MALPKPHM_01658 1.1e-104 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MALPKPHM_01659 7.3e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MALPKPHM_01660 1.5e-181 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MALPKPHM_01661 2.4e-304 norB EGP Major Facilitator
MALPKPHM_01662 4.4e-109 K Bacterial regulatory proteins, tetR family
MALPKPHM_01663 4.6e-118
MALPKPHM_01665 6.8e-107 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
MALPKPHM_01666 2.8e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MALPKPHM_01667 1.3e-165 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MALPKPHM_01668 1.3e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MALPKPHM_01669 1.7e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MALPKPHM_01670 1.4e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MALPKPHM_01672 3.7e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
MALPKPHM_01673 1.5e-186 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MALPKPHM_01674 6.7e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MALPKPHM_01675 1.7e-58
MALPKPHM_01676 2.5e-71 3.6.1.55 L NUDIX domain
MALPKPHM_01677 1.8e-151 EG EamA-like transporter family
MALPKPHM_01679 2.8e-51 L PFAM transposase, IS4 family protein
MALPKPHM_01680 1.4e-105 L PFAM transposase, IS4 family protein
MALPKPHM_01681 4.7e-61 K Tetracyclin repressor, C-terminal all-alpha domain
MALPKPHM_01682 1.5e-55 V ABC-2 type transporter
MALPKPHM_01683 6.8e-80 P ABC-2 family transporter protein
MALPKPHM_01684 2.2e-99 V ABC transporter, ATP-binding protein
MALPKPHM_01685 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MALPKPHM_01686 5.1e-70 rplI J Binds to the 23S rRNA
MALPKPHM_01687 1.7e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MALPKPHM_01688 4e-220
MALPKPHM_01689 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MALPKPHM_01690 5.8e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MALPKPHM_01691 1e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MALPKPHM_01692 1.8e-156 K Helix-turn-helix domain, rpiR family
MALPKPHM_01693 9.1e-107 K Transcriptional regulator C-terminal region
MALPKPHM_01694 5.4e-127 V ABC transporter, ATP-binding protein
MALPKPHM_01695 0.0 ylbB V ABC transporter permease
MALPKPHM_01696 6.7e-206 4.1.1.52 S Amidohydrolase
MALPKPHM_01697 1.9e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MALPKPHM_01699 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
MALPKPHM_01700 1.3e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
MALPKPHM_01701 7e-153 K Helix-turn-helix XRE-family like proteins
MALPKPHM_01702 5.7e-27 S Phospholipase_D-nuclease N-terminal
MALPKPHM_01703 2.6e-121 yxlF V ABC transporter
MALPKPHM_01704 4.5e-103 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MALPKPHM_01705 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MALPKPHM_01706 6.5e-125
MALPKPHM_01707 9.3e-24
MALPKPHM_01710 1e-102 K Bacteriophage CI repressor helix-turn-helix domain
MALPKPHM_01711 1.4e-181 yveB 2.7.4.29 I PAP2 superfamily
MALPKPHM_01712 5.6e-208 mccF V LD-carboxypeptidase
MALPKPHM_01714 2.5e-42
MALPKPHM_01715 1.1e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MALPKPHM_01716 1.1e-40
MALPKPHM_01717 1e-111
MALPKPHM_01718 1.7e-225 EGP Major facilitator Superfamily
MALPKPHM_01719 5.7e-86
MALPKPHM_01720 8.6e-201 T PhoQ Sensor
MALPKPHM_01721 1.6e-120 K Transcriptional regulatory protein, C terminal
MALPKPHM_01722 4.8e-90 ogt 2.1.1.63 L Methyltransferase
MALPKPHM_01723 6.8e-192 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MALPKPHM_01724 7.3e-41
MALPKPHM_01725 3.4e-56 ypaA S Protein of unknown function (DUF1304)
MALPKPHM_01726 4.4e-53 S Protein of unknown function (DUF1516)
MALPKPHM_01727 1.4e-254 pbuO S permease
MALPKPHM_01728 4e-53 S DsrE/DsrF-like family
MALPKPHM_01730 7.8e-137 tauB 3.6.3.36 P ATPases associated with a variety of cellular activities
MALPKPHM_01731 2.4e-181 tauA P NMT1-like family
MALPKPHM_01732 3.9e-142 tauC P Binding-protein-dependent transport system inner membrane component
MALPKPHM_01733 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MALPKPHM_01734 8.1e-257 S Sulphur transport
MALPKPHM_01735 7.6e-113 K LysR substrate binding domain
MALPKPHM_01736 5.3e-150 L PFAM Integrase catalytic region
MALPKPHM_01737 1.5e-89 L Helix-turn-helix domain
MALPKPHM_01738 1.3e-190 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MALPKPHM_01739 3.5e-43
MALPKPHM_01740 5.6e-106 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MALPKPHM_01741 0.0
MALPKPHM_01743 4.1e-123 yqcC S WxL domain surface cell wall-binding
MALPKPHM_01744 1.1e-184 ynjC S Cell surface protein
MALPKPHM_01745 1.4e-270 L Mga helix-turn-helix domain
MALPKPHM_01746 1.1e-170 yhaI S Protein of unknown function (DUF805)
MALPKPHM_01747 6.1e-57
MALPKPHM_01748 2.7e-252 rarA L recombination factor protein RarA
MALPKPHM_01749 4.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MALPKPHM_01750 3.2e-133 K DeoR C terminal sensor domain
MALPKPHM_01751 1.7e-284 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MALPKPHM_01752 6.4e-162 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MALPKPHM_01753 7.3e-242 sgaT 2.7.1.194 S PTS system sugar-specific permease component
MALPKPHM_01754 1.3e-159 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
MALPKPHM_01755 1e-136 magIII L Base excision DNA repair protein, HhH-GPD family
MALPKPHM_01756 8.2e-255 bmr3 EGP Major facilitator Superfamily
MALPKPHM_01757 1.1e-16
MALPKPHM_01759 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MALPKPHM_01760 4.2e-300 oppA E ABC transporter, substratebinding protein
MALPKPHM_01761 7.1e-75
MALPKPHM_01762 2.2e-112
MALPKPHM_01763 7.1e-122
MALPKPHM_01764 6.3e-117 V ATPases associated with a variety of cellular activities
MALPKPHM_01765 1.5e-72
MALPKPHM_01766 6.2e-79 S NUDIX domain
MALPKPHM_01767 2.3e-212 S nuclear-transcribed mRNA catabolic process, no-go decay
MALPKPHM_01768 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
MALPKPHM_01769 3.2e-261 nox 1.6.3.4 C NADH oxidase
MALPKPHM_01770 2.9e-116
MALPKPHM_01771 1.7e-235 S TPM domain
MALPKPHM_01772 4e-129 yxaA S Sulfite exporter TauE/SafE
MALPKPHM_01773 1e-55 ywjH S Protein of unknown function (DUF1634)
MALPKPHM_01775 2.2e-65
MALPKPHM_01776 5.5e-52
MALPKPHM_01777 2.7e-82 fld C Flavodoxin
MALPKPHM_01778 3.4e-36
MALPKPHM_01779 2.5e-26
MALPKPHM_01780 2.6e-172 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MALPKPHM_01781 9.1e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
MALPKPHM_01782 6.4e-38 S Transglycosylase associated protein
MALPKPHM_01783 1e-88 S Protein conserved in bacteria
MALPKPHM_01784 2.5e-29
MALPKPHM_01785 5.1e-61 asp23 S Asp23 family, cell envelope-related function
MALPKPHM_01786 7.9e-65 asp2 S Asp23 family, cell envelope-related function
MALPKPHM_01787 5e-127 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MALPKPHM_01788 6e-115 S Protein of unknown function (DUF969)
MALPKPHM_01789 2.6e-145 S Protein of unknown function (DUF979)
MALPKPHM_01790 3.8e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MALPKPHM_01791 4.6e-106 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MALPKPHM_01793 1e-127 cobQ S glutamine amidotransferase
MALPKPHM_01794 3.7e-66
MALPKPHM_01795 8.1e-134 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MALPKPHM_01796 2.4e-142 noc K Belongs to the ParB family
MALPKPHM_01797 7.4e-138 soj D Sporulation initiation inhibitor
MALPKPHM_01798 2e-155 spo0J K Belongs to the ParB family
MALPKPHM_01799 1.3e-30 yyzM S Bacterial protein of unknown function (DUF951)
MALPKPHM_01800 1.5e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MALPKPHM_01801 2.1e-140 XK27_01040 S Protein of unknown function (DUF1129)
MALPKPHM_01802 5.1e-268 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MALPKPHM_01803 5.3e-119
MALPKPHM_01804 2.5e-121 K response regulator
MALPKPHM_01805 2.7e-219 hpk31 2.7.13.3 T Histidine kinase
MALPKPHM_01806 5.3e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MALPKPHM_01807 3.4e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MALPKPHM_01808 2.7e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MALPKPHM_01809 5.4e-141 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
MALPKPHM_01810 1.3e-162 yvgN C Aldo keto reductase
MALPKPHM_01811 1.9e-141 iolR K DeoR C terminal sensor domain
MALPKPHM_01812 1.1e-267 iolT EGP Major facilitator Superfamily
MALPKPHM_01813 7.6e-272 iolA 1.2.1.18, 1.2.1.27 C Belongs to the aldehyde dehydrogenase family
MALPKPHM_01814 8.4e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MALPKPHM_01815 1.6e-177 iolC 2.7.1.92 H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MALPKPHM_01816 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MALPKPHM_01817 5.4e-192 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MALPKPHM_01818 1.8e-195 iolG2 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
MALPKPHM_01819 2.6e-174 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MALPKPHM_01820 3.3e-158 iolJ 4.1.2.13, 4.1.2.29 G Fructose-bisphosphate aldolase class-II
MALPKPHM_01821 1.7e-66 iolK S Tautomerase enzyme
MALPKPHM_01822 2e-158 iolI 5.3.99.11 G Xylose isomerase-like TIM barrel
MALPKPHM_01823 7.8e-168 iolH G Xylose isomerase-like TIM barrel
MALPKPHM_01824 4e-145 gntR K rpiR family
MALPKPHM_01825 1.4e-168 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
MALPKPHM_01826 2.3e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MALPKPHM_01827 3.8e-206 gntP EG Gluconate
MALPKPHM_01828 7.6e-58
MALPKPHM_01829 4.1e-130 fhuC 3.6.3.35 P ABC transporter
MALPKPHM_01830 3e-134 znuB U ABC 3 transport family
MALPKPHM_01831 5.4e-166 T Calcineurin-like phosphoesterase superfamily domain
MALPKPHM_01832 2.7e-160 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MALPKPHM_01833 0.0 pepF E oligoendopeptidase F
MALPKPHM_01834 2e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MALPKPHM_01835 2.3e-246 brnQ U Component of the transport system for branched-chain amino acids
MALPKPHM_01836 7e-71 T Sh3 type 3 domain protein
MALPKPHM_01837 2.2e-134 glcR K DeoR C terminal sensor domain
MALPKPHM_01838 2.9e-145 M Glycosyltransferase like family 2
MALPKPHM_01839 3.1e-133 XK27_06755 S Protein of unknown function (DUF975)
MALPKPHM_01840 1.1e-51
MALPKPHM_01841 2.9e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MALPKPHM_01842 9.6e-172 draG O ADP-ribosylglycohydrolase
MALPKPHM_01843 9.9e-291 S ABC transporter
MALPKPHM_01844 8.8e-136 ksgA 2.1.1.182, 2.1.1.197, 2.5.1.134 J rRNA (adenine-N6,N6-)-dimethyltransferase activity
MALPKPHM_01846 1.5e-99
MALPKPHM_01847 1.7e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MALPKPHM_01848 5.6e-275 emrY EGP Major facilitator Superfamily
MALPKPHM_01849 3.9e-81 merR K MerR HTH family regulatory protein
MALPKPHM_01850 8.1e-266 lmrB EGP Major facilitator Superfamily
MALPKPHM_01851 1.1e-114 S Domain of unknown function (DUF4811)
MALPKPHM_01852 2.3e-119 3.6.1.27 I Acid phosphatase homologues
MALPKPHM_01853 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MALPKPHM_01854 9.2e-279 ytgP S Polysaccharide biosynthesis protein
MALPKPHM_01855 1.5e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MALPKPHM_01856 3.3e-35 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MALPKPHM_01857 4.1e-142 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MALPKPHM_01858 1e-94 FNV0100 F NUDIX domain
MALPKPHM_01860 4.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MALPKPHM_01861 5.1e-226 malY 4.4.1.8 E Aminotransferase, class I
MALPKPHM_01862 9.9e-223 cpdA S Calcineurin-like phosphoesterase
MALPKPHM_01863 1.5e-37 gcvR T Belongs to the UPF0237 family
MALPKPHM_01864 6.7e-243 XK27_08635 S UPF0210 protein
MALPKPHM_01865 2.6e-213 coiA 3.6.4.12 S Competence protein
MALPKPHM_01866 1.5e-115 yjbH Q Thioredoxin
MALPKPHM_01867 2.4e-104 yjbK S CYTH
MALPKPHM_01868 2.7e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
MALPKPHM_01869 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MALPKPHM_01870 1.1e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MALPKPHM_01871 2e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MALPKPHM_01872 4.2e-110 cutC P Participates in the control of copper homeostasis
MALPKPHM_01873 3.9e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MALPKPHM_01874 3.9e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MALPKPHM_01875 1.2e-61 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MALPKPHM_01876 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MALPKPHM_01877 7.4e-191 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MALPKPHM_01878 3.7e-171 corA P CorA-like Mg2+ transporter protein
MALPKPHM_01879 6.2e-154 rrmA 2.1.1.187 H Methyltransferase
MALPKPHM_01880 2.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MALPKPHM_01881 5.4e-71 WQ51_03320 S Protein of unknown function (DUF1149)
MALPKPHM_01882 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MALPKPHM_01883 5.1e-229 ymfF S Peptidase M16 inactive domain protein
MALPKPHM_01884 1.7e-243 ymfH S Peptidase M16
MALPKPHM_01885 1.3e-128 IQ Enoyl-(Acyl carrier protein) reductase
MALPKPHM_01886 3.7e-115 ymfM S Helix-turn-helix domain
MALPKPHM_01887 3.5e-103 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MALPKPHM_01888 9.5e-228 cinA 3.5.1.42 S Belongs to the CinA family
MALPKPHM_01889 1.9e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MALPKPHM_01890 7.8e-12
MALPKPHM_01891 1.7e-242 rny S Endoribonuclease that initiates mRNA decay
MALPKPHM_01892 6.8e-116 yvyE 3.4.13.9 S YigZ family
MALPKPHM_01893 1.7e-235 comFA L Helicase C-terminal domain protein
MALPKPHM_01894 1.3e-90 comFC S Competence protein
MALPKPHM_01895 5.4e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MALPKPHM_01896 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MALPKPHM_01897 8.9e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MALPKPHM_01898 1.9e-124 ftsE D ABC transporter
MALPKPHM_01899 1.8e-159 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MALPKPHM_01900 9.1e-198 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
MALPKPHM_01901 5.2e-130 K response regulator
MALPKPHM_01902 3.4e-305 phoR 2.7.13.3 T Histidine kinase
MALPKPHM_01903 5.2e-156 pstS P Phosphate
MALPKPHM_01904 3.4e-161 pstC P probably responsible for the translocation of the substrate across the membrane
MALPKPHM_01905 1.1e-156 pstA P Phosphate transport system permease protein PstA
MALPKPHM_01906 6.9e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MALPKPHM_01907 1.8e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MALPKPHM_01908 1e-119 phoU P Plays a role in the regulation of phosphate uptake
MALPKPHM_01909 2.5e-214 yvlB S Putative adhesin
MALPKPHM_01910 2.1e-31
MALPKPHM_01911 1.3e-46 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MALPKPHM_01912 2.8e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MALPKPHM_01913 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MALPKPHM_01914 6.9e-195 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MALPKPHM_01915 3.3e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MALPKPHM_01916 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MALPKPHM_01917 1.7e-82 T Transcriptional regulatory protein, C terminal
MALPKPHM_01918 2.6e-114 T His Kinase A (phosphoacceptor) domain
MALPKPHM_01919 1e-90 V ABC transporter
MALPKPHM_01920 2.5e-245 V FtsX-like permease family
MALPKPHM_01921 1.6e-117 yfbR S HD containing hydrolase-like enzyme
MALPKPHM_01922 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MALPKPHM_01923 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MALPKPHM_01924 8.7e-85 S Short repeat of unknown function (DUF308)
MALPKPHM_01925 6.3e-165 rapZ S Displays ATPase and GTPase activities
MALPKPHM_01926 7.7e-191 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MALPKPHM_01927 1.6e-171 whiA K May be required for sporulation
MALPKPHM_01928 5.5e-80 ohrR K helix_turn_helix multiple antibiotic resistance protein
MALPKPHM_01929 2.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MALPKPHM_01931 3.6e-188 cggR K Putative sugar-binding domain
MALPKPHM_01932 2.2e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MALPKPHM_01933 1.5e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MALPKPHM_01934 1.7e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MALPKPHM_01935 5.3e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MALPKPHM_01936 1.9e-62
MALPKPHM_01937 5.7e-294 clcA P chloride
MALPKPHM_01938 1.7e-60
MALPKPHM_01939 9.3e-31 secG U Preprotein translocase
MALPKPHM_01940 1.9e-138 est 3.1.1.1 S Serine aminopeptidase, S33
MALPKPHM_01941 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MALPKPHM_01942 3.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MALPKPHM_01943 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MALPKPHM_01944 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MALPKPHM_01945 5.3e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MALPKPHM_01946 1.3e-48
MALPKPHM_01947 4.4e-17
MALPKPHM_01948 4.6e-238 YSH1 S Metallo-beta-lactamase superfamily
MALPKPHM_01949 4.4e-239 malE G Bacterial extracellular solute-binding protein
MALPKPHM_01950 1.9e-147 malF G Binding-protein-dependent transport system inner membrane component
MALPKPHM_01951 3.4e-166 malG P ABC-type sugar transport systems, permease components
MALPKPHM_01952 3.5e-194 malK P ATPases associated with a variety of cellular activities
MALPKPHM_01953 1.3e-102 3.2.2.20 K Acetyltransferase (GNAT) domain
MALPKPHM_01954 9e-92 yxjI
MALPKPHM_01955 2e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
MALPKPHM_01956 4.6e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MALPKPHM_01957 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MALPKPHM_01958 1e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MALPKPHM_01959 4.4e-166 natA S ABC transporter, ATP-binding protein
MALPKPHM_01960 2.2e-216 ysdA CP ABC-2 family transporter protein
MALPKPHM_01961 2e-97 dnaQ 2.7.7.7 L DNA polymerase III
MALPKPHM_01962 2.1e-148 xth 3.1.11.2 L exodeoxyribonuclease III
MALPKPHM_01963 1.1e-158 murB 1.3.1.98 M Cell wall formation
MALPKPHM_01964 0.0 yjcE P Sodium proton antiporter
MALPKPHM_01965 2.9e-96 puuR K Cupin domain
MALPKPHM_01966 4.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MALPKPHM_01967 1.7e-148 potB P ABC transporter permease
MALPKPHM_01968 1.3e-143 potC P ABC transporter permease
MALPKPHM_01969 3.6e-207 potD P ABC transporter
MALPKPHM_01970 4.9e-12 T SpoVT / AbrB like domain
MALPKPHM_01972 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
MALPKPHM_01973 6.4e-117 K Transcriptional regulator
MALPKPHM_01974 7e-185 V ABC transporter
MALPKPHM_01975 1e-128 V AAA domain, putative AbiEii toxin, Type IV TA system
MALPKPHM_01976 1e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MALPKPHM_01977 1.5e-168 ybbR S YbbR-like protein
MALPKPHM_01978 9.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MALPKPHM_01979 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MALPKPHM_01980 0.0 pepF2 E Oligopeptidase F
MALPKPHM_01981 9.7e-91 S VanZ like family
MALPKPHM_01982 3.4e-132 yebC K Transcriptional regulatory protein
MALPKPHM_01983 1.3e-127 comGA NU Type II IV secretion system protein
MALPKPHM_01984 2.5e-167 comGB NU type II secretion system
MALPKPHM_01985 1.1e-47
MALPKPHM_01987 1.1e-47
MALPKPHM_01988 2.9e-76
MALPKPHM_01989 1.9e-26
MALPKPHM_01990 6.9e-184 ytxK 2.1.1.72 L N-6 DNA Methylase
MALPKPHM_01991 9.5e-72
MALPKPHM_01992 3.1e-248 cycA E Amino acid permease
MALPKPHM_01993 5.8e-143 arbV 2.3.1.51 I Phosphate acyltransferases
MALPKPHM_01994 9.5e-163 arbx M Glycosyl transferase family 8
MALPKPHM_01995 1.7e-179 arbY M family 8
MALPKPHM_01996 1.3e-162 arbZ I Phosphate acyltransferases
MALPKPHM_01997 0.0 rafA 3.2.1.22 G alpha-galactosidase
MALPKPHM_01999 1.7e-69 S SdpI/YhfL protein family
MALPKPHM_02000 1.3e-96 K response regulator
MALPKPHM_02001 9.3e-273 yclK 2.7.13.3 T Histidine kinase
MALPKPHM_02002 1.3e-93 yhbS S acetyltransferase
MALPKPHM_02003 7.6e-31
MALPKPHM_02004 5.2e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
MALPKPHM_02005 3.2e-81
MALPKPHM_02006 5.3e-59
MALPKPHM_02007 7.9e-249 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
MALPKPHM_02009 5.2e-175 S response to antibiotic
MALPKPHM_02011 3.7e-117 tnpB L Putative transposase DNA-binding domain
MALPKPHM_02012 2.1e-85 tnpB L Putative transposase DNA-binding domain
MALPKPHM_02013 4.9e-108 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
MALPKPHM_02014 2e-28 yjgN S Bacterial protein of unknown function (DUF898)
MALPKPHM_02015 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MALPKPHM_02016 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MALPKPHM_02017 6.8e-204 camS S sex pheromone
MALPKPHM_02018 4.9e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MALPKPHM_02019 6.7e-265 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MALPKPHM_02020 9.5e-280 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MALPKPHM_02021 7.5e-194 yegS 2.7.1.107 G Lipid kinase
MALPKPHM_02022 5.2e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MALPKPHM_02023 1.2e-216 yttB EGP Major facilitator Superfamily
MALPKPHM_02024 6e-146 cof S Sucrose-6F-phosphate phosphohydrolase
MALPKPHM_02025 3.1e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
MALPKPHM_02026 0.0 pepO 3.4.24.71 O Peptidase family M13
MALPKPHM_02027 3.4e-74 K Acetyltransferase (GNAT) domain
MALPKPHM_02028 1.8e-164 degV S Uncharacterised protein, DegV family COG1307
MALPKPHM_02029 1.4e-119 qmcA O prohibitin homologues
MALPKPHM_02030 3.2e-29
MALPKPHM_02031 2.8e-134 lys M Glycosyl hydrolases family 25
MALPKPHM_02032 1.1e-59 S Protein of unknown function (DUF1093)
MALPKPHM_02033 2e-61 S Domain of unknown function (DUF4828)
MALPKPHM_02034 5e-176 mocA S Oxidoreductase
MALPKPHM_02035 3.2e-234 yfmL 3.6.4.13 L DEAD DEAH box helicase
MALPKPHM_02036 2e-47 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MALPKPHM_02037 5.6e-71 S Domain of unknown function (DUF3284)
MALPKPHM_02039 3.4e-07
MALPKPHM_02040 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MALPKPHM_02041 4.5e-238 pepS E Thermophilic metalloprotease (M29)
MALPKPHM_02042 2.7e-111 K Bacterial regulatory proteins, tetR family
MALPKPHM_02043 1.4e-259 S Uncharacterized protein conserved in bacteria (DUF2252)
MALPKPHM_02044 7.3e-178 yihY S Belongs to the UPF0761 family
MALPKPHM_02045 1.9e-80 fld C Flavodoxin
MALPKPHM_02046 4.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
MALPKPHM_02047 5.8e-194 M Glycosyltransferase like family 2
MALPKPHM_02049 4.5e-29
MALPKPHM_02050 4.9e-125 M lipopolysaccharide 3-alpha-galactosyltransferase activity
MALPKPHM_02051 6.8e-198 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MALPKPHM_02052 2.2e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MALPKPHM_02054 6.8e-307 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MALPKPHM_02055 0.0 S Bacterial membrane protein YfhO
MALPKPHM_02056 3.1e-309 S Psort location CytoplasmicMembrane, score
MALPKPHM_02057 4.3e-172 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MALPKPHM_02058 2.1e-109
MALPKPHM_02059 8.6e-168 yqjA S Putative aromatic acid exporter C-terminal domain
MALPKPHM_02060 2.1e-31 cspC K Cold shock protein
MALPKPHM_02061 9.8e-28 chpR T PFAM SpoVT AbrB
MALPKPHM_02062 4.9e-82 yvbK 3.1.3.25 K GNAT family
MALPKPHM_02063 6.6e-108 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
MALPKPHM_02064 1.2e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MALPKPHM_02065 1.6e-241 pbuX F xanthine permease
MALPKPHM_02066 3e-204 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MALPKPHM_02067 4.8e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MALPKPHM_02068 1.3e-102
MALPKPHM_02069 1.6e-129
MALPKPHM_02070 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MALPKPHM_02071 1.5e-109 vanZ V VanZ like family
MALPKPHM_02072 3.8e-151 glcU U sugar transport
MALPKPHM_02073 7.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
MALPKPHM_02075 1.2e-45 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
MALPKPHM_02076 7.5e-115 F DNA/RNA non-specific endonuclease
MALPKPHM_02077 1.4e-77 yttA 2.7.13.3 S Pfam Transposase IS66
MALPKPHM_02078 3e-231 wbbX GT2,GT4 M Glycosyl transferases group 1
MALPKPHM_02079 1.4e-172 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MALPKPHM_02080 6e-82 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
MALPKPHM_02085 3.7e-168 L PFAM transposase, IS4 family protein
MALPKPHM_02086 8e-20 L PFAM transposase, IS4 family protein
MALPKPHM_02089 1.2e-17
MALPKPHM_02090 3.3e-193 yttB EGP Major facilitator Superfamily
MALPKPHM_02091 2.8e-284 pipD E Dipeptidase
MALPKPHM_02093 1.1e-08
MALPKPHM_02094 6.9e-133 G Phosphoglycerate mutase family
MALPKPHM_02095 1.1e-121 K Bacterial regulatory proteins, tetR family
MALPKPHM_02096 0.0 ycfI V ABC transporter, ATP-binding protein
MALPKPHM_02097 0.0 yfiC V ABC transporter
MALPKPHM_02098 1e-139 S NADPH-dependent FMN reductase
MALPKPHM_02099 2.6e-163 1.13.11.2 S glyoxalase
MALPKPHM_02100 3.7e-190 ampC V Beta-lactamase
MALPKPHM_02101 1e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MALPKPHM_02102 6e-111 tdk 2.7.1.21 F thymidine kinase
MALPKPHM_02103 9e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MALPKPHM_02104 8.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MALPKPHM_02105 3.5e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MALPKPHM_02106 4.4e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MALPKPHM_02107 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MALPKPHM_02108 1.1e-124 atpB C it plays a direct role in the translocation of protons across the membrane
MALPKPHM_02109 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MALPKPHM_02110 1.3e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MALPKPHM_02111 1.5e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MALPKPHM_02112 7.2e-286 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MALPKPHM_02113 2.3e-162 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MALPKPHM_02114 1e-10
MALPKPHM_02115 4.4e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MALPKPHM_02116 1.6e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MALPKPHM_02117 6.4e-32 ywzB S Protein of unknown function (DUF1146)
MALPKPHM_02118 4.5e-180 mbl D Cell shape determining protein MreB Mrl
MALPKPHM_02119 1.4e-25 epuA S DNA-directed RNA polymerase subunit beta
MALPKPHM_02120 1.6e-54 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MALPKPHM_02121 1.3e-31 S Protein of unknown function (DUF2969)
MALPKPHM_02122 7.6e-222 rodA D Belongs to the SEDS family
MALPKPHM_02123 1.2e-46 gcvH E glycine cleavage
MALPKPHM_02124 4.2e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MALPKPHM_02125 1.9e-147 P Belongs to the nlpA lipoprotein family
MALPKPHM_02126 5e-148 P Belongs to the nlpA lipoprotein family
MALPKPHM_02127 9.1e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MALPKPHM_02128 1.1e-105 metI P ABC transporter permease
MALPKPHM_02129 1.9e-141 sufC O FeS assembly ATPase SufC
MALPKPHM_02130 1.3e-190 sufD O FeS assembly protein SufD
MALPKPHM_02131 2.1e-224 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MALPKPHM_02132 7.2e-77 nifU C SUF system FeS assembly protein, NifU family
MALPKPHM_02133 1.2e-279 sufB O assembly protein SufB
MALPKPHM_02134 1.8e-26
MALPKPHM_02135 1.1e-65 yueI S Protein of unknown function (DUF1694)
MALPKPHM_02136 1.1e-178 S Protein of unknown function (DUF2785)
MALPKPHM_02137 5e-105 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MALPKPHM_02138 3.3e-33 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MALPKPHM_02139 1.5e-83 usp6 T universal stress protein
MALPKPHM_02140 4.9e-39
MALPKPHM_02142 1.6e-236 rarA L recombination factor protein RarA
MALPKPHM_02143 0.0 6.3.2.2, 6.3.2.4 M Mur ligase middle domain protein
MALPKPHM_02144 1.5e-71 yueI S Protein of unknown function (DUF1694)
MALPKPHM_02145 9.1e-107 yktB S Belongs to the UPF0637 family
MALPKPHM_02146 2.2e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MALPKPHM_02147 3.6e-149 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MALPKPHM_02148 1.1e-119 G Phosphoglycerate mutase family
MALPKPHM_02149 3.6e-154 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MALPKPHM_02150 2.9e-168 IQ NAD dependent epimerase/dehydratase family
MALPKPHM_02151 1.7e-136 pnuC H nicotinamide mononucleotide transporter
MALPKPHM_02152 4.4e-132 dck 2.7.1.74 F deoxynucleoside kinase
MALPKPHM_02153 7.5e-157 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
MALPKPHM_02154 2.7e-307 oppA E ABC transporter, substratebinding protein
MALPKPHM_02155 3.9e-154 T GHKL domain
MALPKPHM_02156 4.5e-67 T Transcriptional regulatory protein, C terminal
MALPKPHM_02157 3.3e-41 T Transcriptional regulatory protein, C terminal
MALPKPHM_02158 1.6e-166 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
MALPKPHM_02159 7e-128 S ABC-2 family transporter protein
MALPKPHM_02160 7.4e-158 K Transcriptional regulator
MALPKPHM_02161 1.3e-75 yphH S Cupin domain
MALPKPHM_02162 2.7e-54 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
MALPKPHM_02163 7.9e-36
MALPKPHM_02164 4.1e-27 K Psort location Cytoplasmic, score
MALPKPHM_02165 2.8e-97 1.6.5.5 C Zinc-binding dehydrogenase
MALPKPHM_02166 1.6e-82 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MALPKPHM_02167 3.4e-163 2.3.1.128 K Acetyltransferase (GNAT) domain
MALPKPHM_02168 1e-84 K Acetyltransferase (GNAT) domain
MALPKPHM_02169 5.7e-155 S Uncharacterised protein, DegV family COG1307
MALPKPHM_02170 1.2e-113
MALPKPHM_02171 1.1e-102 desR K helix_turn_helix, Lux Regulon
MALPKPHM_02172 9.8e-200 desK 2.7.13.3 T Histidine kinase
MALPKPHM_02173 4.1e-128 yvfS V ABC-2 type transporter
MALPKPHM_02175 2.7e-208 tnpB L Putative transposase DNA-binding domain
MALPKPHM_02176 2.3e-151 yvfR V ABC transporter
MALPKPHM_02177 8.7e-276
MALPKPHM_02178 1.1e-173
MALPKPHM_02179 1.3e-63 S Protein of unknown function C-terminus (DUF2399)
MALPKPHM_02180 9.8e-83 K Acetyltransferase (GNAT) domain
MALPKPHM_02181 6.2e-69
MALPKPHM_02182 0.0 yhgF K Tex-like protein N-terminal domain protein
MALPKPHM_02183 1.1e-80
MALPKPHM_02184 1.9e-138 puuD S peptidase C26
MALPKPHM_02185 2.2e-227 steT E Amino acid permease
MALPKPHM_02186 4.7e-91 K Cro/C1-type HTH DNA-binding domain
MALPKPHM_02187 2.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MALPKPHM_02188 1.7e-84 ytsP 1.8.4.14 T GAF domain-containing protein
MALPKPHM_02189 7.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MALPKPHM_02190 5.4e-217 iscS2 2.8.1.7 E Aminotransferase class V
MALPKPHM_02191 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MALPKPHM_02192 1.5e-115 rex K CoA binding domain
MALPKPHM_02193 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MALPKPHM_02194 9.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MALPKPHM_02195 2.3e-116 S Haloacid dehalogenase-like hydrolase
MALPKPHM_02196 2.7e-118 radC L DNA repair protein
MALPKPHM_02197 7.8e-180 mreB D cell shape determining protein MreB
MALPKPHM_02198 3.2e-150 mreC M Involved in formation and maintenance of cell shape
MALPKPHM_02199 1.5e-81 mreD M rod shape-determining protein MreD
MALPKPHM_02200 1.4e-113 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MALPKPHM_02201 9.7e-141 minD D Belongs to the ParA family
MALPKPHM_02202 4.7e-109 artQ P ABC transporter permease
MALPKPHM_02203 6.4e-111 glnQ 3.6.3.21 E ABC transporter
MALPKPHM_02204 8.1e-151 aatB ET ABC transporter substrate-binding protein
MALPKPHM_02205 2.3e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MALPKPHM_02206 8.6e-09 S Protein of unknown function (DUF4044)
MALPKPHM_02207 2.5e-07 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MALPKPHM_02208 4.2e-53
MALPKPHM_02209 4.8e-78 mraZ K Belongs to the MraZ family
MALPKPHM_02210 1.8e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MALPKPHM_02211 6.2e-58 ftsL D cell division protein FtsL
MALPKPHM_02212 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MALPKPHM_02213 1.2e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MALPKPHM_02214 1e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MALPKPHM_02215 2.2e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MALPKPHM_02216 1.3e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MALPKPHM_02217 1.4e-232 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MALPKPHM_02218 3.1e-218 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MALPKPHM_02219 5.7e-77 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MALPKPHM_02220 5.2e-44 yggT D integral membrane protein
MALPKPHM_02221 6.4e-145 ylmH S S4 domain protein
MALPKPHM_02222 8.5e-81 divIVA D DivIVA protein
MALPKPHM_02223 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MALPKPHM_02224 8.2e-37 cspA K Cold shock protein
MALPKPHM_02225 1.5e-145 pstS P Phosphate
MALPKPHM_02226 3.6e-263 ydiC1 EGP Major facilitator Superfamily
MALPKPHM_02227 6.2e-208 yaaN P Toxic anion resistance protein (TelA)
MALPKPHM_02228 6.9e-116 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MALPKPHM_02229 1.2e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MALPKPHM_02230 5.8e-34
MALPKPHM_02231 2.4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MALPKPHM_02232 3.4e-219 iscS 2.8.1.7 E Aminotransferase class V
MALPKPHM_02233 2.6e-58 XK27_04120 S Putative amino acid metabolism
MALPKPHM_02234 0.0 uvrA2 L ABC transporter
MALPKPHM_02235 2.1e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MALPKPHM_02236 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MALPKPHM_02237 3.5e-115 S Repeat protein
MALPKPHM_02238 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MALPKPHM_02239 7.9e-243 els S Sterol carrier protein domain
MALPKPHM_02240 1.1e-183 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MALPKPHM_02241 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MALPKPHM_02242 4.9e-31 ykzG S Belongs to the UPF0356 family
MALPKPHM_02244 3.4e-74
MALPKPHM_02245 1.9e-25
MALPKPHM_02246 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MALPKPHM_02247 2.1e-65 S E1-E2 ATPase
MALPKPHM_02248 2.8e-58 S E1-E2 ATPase
MALPKPHM_02249 8e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MALPKPHM_02250 4.8e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MALPKPHM_02251 3.1e-242 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MALPKPHM_02252 2.4e-259 lpdA 1.8.1.4 C Dehydrogenase
MALPKPHM_02253 2.4e-156 1.1.1.27 C L-malate dehydrogenase activity
MALPKPHM_02254 1.4e-46 yktA S Belongs to the UPF0223 family
MALPKPHM_02255 5e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MALPKPHM_02256 0.0 typA T GTP-binding protein TypA
MALPKPHM_02257 6.5e-210 ftsW D Belongs to the SEDS family
MALPKPHM_02258 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MALPKPHM_02259 3.8e-57 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MALPKPHM_02260 6e-100 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MALPKPHM_02261 1.1e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MALPKPHM_02262 2.3e-193 ylbL T Belongs to the peptidase S16 family
MALPKPHM_02263 1.3e-106 comEA L Competence protein ComEA
MALPKPHM_02264 0.0 comEC S Competence protein ComEC
MALPKPHM_02265 3.5e-194 holA 2.7.7.7 L DNA polymerase III delta subunit
MALPKPHM_02266 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
MALPKPHM_02267 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MALPKPHM_02268 1.7e-117
MALPKPHM_02269 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MALPKPHM_02270 2.5e-161 S Tetratricopeptide repeat
MALPKPHM_02271 1.2e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MALPKPHM_02272 5.9e-83 M Protein of unknown function (DUF3737)
MALPKPHM_02273 6.4e-131 cobB K Sir2 family
MALPKPHM_02274 1.9e-62 pcaC 4.1.1.44 S Carboxymuconolactone decarboxylase family
MALPKPHM_02275 9.3e-65 rmeD K helix_turn_helix, mercury resistance
MALPKPHM_02276 0.0 yknV V ABC transporter
MALPKPHM_02277 7.2e-275 L PFAM Integrase core domain
MALPKPHM_02278 2.7e-196 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MALPKPHM_02279 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MALPKPHM_02280 2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MALPKPHM_02281 1e-47 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MALPKPHM_02282 2.3e-20
MALPKPHM_02283 1.5e-259 glnPH2 P ABC transporter permease
MALPKPHM_02284 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MALPKPHM_02285 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MALPKPHM_02287 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
MALPKPHM_02288 2.9e-157 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MALPKPHM_02289 2.9e-131 fruR K DeoR C terminal sensor domain
MALPKPHM_02290 1.9e-234 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MALPKPHM_02291 0.0 oatA I Acyltransferase
MALPKPHM_02292 1.5e-183 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MALPKPHM_02293 1.1e-141 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MALPKPHM_02294 1.3e-46 yrvD S Lipopolysaccharide assembly protein A domain
MALPKPHM_02295 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MALPKPHM_02296 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MALPKPHM_02297 1.8e-93 M1-874 K Domain of unknown function (DUF1836)
MALPKPHM_02298 2.8e-301 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
MALPKPHM_02299 3.1e-145
MALPKPHM_02300 1.3e-19 S Protein of unknown function (DUF2929)
MALPKPHM_02301 0.0 dnaE 2.7.7.7 L DNA polymerase
MALPKPHM_02302 3.5e-177 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MALPKPHM_02303 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MALPKPHM_02304 1.9e-72 yeaL S Protein of unknown function (DUF441)
MALPKPHM_02305 5.9e-163 cvfB S S1 domain
MALPKPHM_02306 7.4e-166 xerD D recombinase XerD
MALPKPHM_02307 3.4e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MALPKPHM_02308 7.3e-127 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MALPKPHM_02309 1.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MALPKPHM_02310 9.4e-138 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MALPKPHM_02311 2.4e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MALPKPHM_02312 1.4e-45 fer C 4Fe-4S single cluster domain of Ferredoxin I
MALPKPHM_02313 8e-185 ypbB 5.1.3.1 S Helix-turn-helix domain
MALPKPHM_02314 5.5e-264 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
MALPKPHM_02315 5.5e-54 M Lysin motif
MALPKPHM_02316 7.7e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MALPKPHM_02317 1.1e-218 rpsA 1.17.7.4 J Ribosomal protein S1
MALPKPHM_02318 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MALPKPHM_02319 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MALPKPHM_02320 2.6e-236 S Tetratricopeptide repeat protein
MALPKPHM_02321 4.8e-149 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MALPKPHM_02322 6.2e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MALPKPHM_02323 3.7e-84
MALPKPHM_02324 0.0 yfmR S ABC transporter, ATP-binding protein
MALPKPHM_02325 3.8e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MALPKPHM_02326 6.7e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MALPKPHM_02327 9.6e-115 hly S protein, hemolysin III
MALPKPHM_02328 2.3e-148 DegV S EDD domain protein, DegV family
MALPKPHM_02329 3.9e-156 ypmR E GDSL-like Lipase/Acylhydrolase
MALPKPHM_02330 2.4e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MALPKPHM_02331 6.8e-95 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MALPKPHM_02332 2.3e-40 yozE S Belongs to the UPF0346 family
MALPKPHM_02333 8.8e-257 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MALPKPHM_02334 1e-85 S Psort location Cytoplasmic, score
MALPKPHM_02335 2.1e-12
MALPKPHM_02336 7.6e-120 S Domain of unknown function (DUF4918)
MALPKPHM_02337 6.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MALPKPHM_02338 9.6e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MALPKPHM_02339 1.5e-144 dprA LU DNA protecting protein DprA
MALPKPHM_02340 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MALPKPHM_02341 4.7e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MALPKPHM_02342 1.8e-167 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MALPKPHM_02343 5.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MALPKPHM_02344 5e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MALPKPHM_02345 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
MALPKPHM_02346 3.1e-110 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MALPKPHM_02347 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MALPKPHM_02348 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MALPKPHM_02349 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MALPKPHM_02350 4.3e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MALPKPHM_02351 1.8e-181 K LysR substrate binding domain
MALPKPHM_02352 2.1e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
MALPKPHM_02353 2.2e-207 xerS L Belongs to the 'phage' integrase family
MALPKPHM_02354 4.2e-303 ysaB V FtsX-like permease family
MALPKPHM_02355 4.3e-41 ysaB V FtsX-like permease family
MALPKPHM_02356 1e-134 XK27_05695 V ABC transporter, ATP-binding protein
MALPKPHM_02357 1.4e-173 T Histidine kinase-like ATPases
MALPKPHM_02358 2.8e-128 T Transcriptional regulatory protein, C terminal
MALPKPHM_02359 3.6e-219 EGP Transmembrane secretion effector
MALPKPHM_02360 7.1e-68 msi198 K Acetyltransferase (GNAT) domain
MALPKPHM_02361 5.9e-70 K Acetyltransferase (GNAT) domain
MALPKPHM_02362 2.6e-112 nfnB 1.5.1.34 C Nitroreductase family
MALPKPHM_02363 2e-146 Q Fumarylacetoacetate (FAA) hydrolase family
MALPKPHM_02364 1.6e-205 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MALPKPHM_02365 6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
MALPKPHM_02366 1.6e-57 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MALPKPHM_02367 2.1e-132 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MALPKPHM_02368 3.5e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MALPKPHM_02369 2.3e-113 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MALPKPHM_02370 6.3e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MALPKPHM_02371 4.6e-225 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MALPKPHM_02372 5.9e-109 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MALPKPHM_02373 3.8e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MALPKPHM_02374 2.4e-206 hisC 2.6.1.9 E Cys/Met metabolism PLP-dependent enzyme
MALPKPHM_02375 4.5e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
MALPKPHM_02376 1.6e-160 degV S EDD domain protein, DegV family
MALPKPHM_02378 0.0 FbpA K Fibronectin-binding protein
MALPKPHM_02379 6.2e-51 S MazG-like family
MALPKPHM_02380 1.2e-192 pfoS S Phosphotransferase system, EIIC
MALPKPHM_02381 5.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MALPKPHM_02382 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MALPKPHM_02383 1.9e-153 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MALPKPHM_02384 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MALPKPHM_02385 1e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MALPKPHM_02386 2.5e-239 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MALPKPHM_02387 7.3e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MALPKPHM_02388 4.5e-236 pyrP F Permease
MALPKPHM_02389 1.7e-96 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MALPKPHM_02390 5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MALPKPHM_02391 2.7e-81 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MALPKPHM_02392 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MALPKPHM_02393 4.1e-63 S Family of unknown function (DUF5322)
MALPKPHM_02394 2.5e-68 rnhA 3.1.26.4 L Ribonuclease HI
MALPKPHM_02395 1.3e-90 XK27_02070 S Nitroreductase family
MALPKPHM_02396 2.6e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MALPKPHM_02397 3.3e-55
MALPKPHM_02398 4.8e-271 K Mga helix-turn-helix domain
MALPKPHM_02399 4.5e-38 nrdH O Glutaredoxin
MALPKPHM_02400 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MALPKPHM_02401 4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MALPKPHM_02402 1.4e-164 K Transcriptional regulator
MALPKPHM_02403 0.0 pepO 3.4.24.71 O Peptidase family M13
MALPKPHM_02404 4.8e-193 lplA 6.3.1.20 H Lipoate-protein ligase
MALPKPHM_02405 1.5e-33
MALPKPHM_02406 1e-173 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MALPKPHM_02407 1.8e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MALPKPHM_02408 1.8e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MALPKPHM_02409 3.3e-106 ypsA S Belongs to the UPF0398 family
MALPKPHM_02410 5.7e-120 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MALPKPHM_02411 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MALPKPHM_02412 1.2e-85 comEB 3.5.4.12 F ComE operon protein 2
MALPKPHM_02413 1.4e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MALPKPHM_02414 6.2e-111 dnaD L DnaD domain protein
MALPKPHM_02415 9.3e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MALPKPHM_02416 7.7e-219 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MALPKPHM_02417 2.1e-85 ypmB S Protein conserved in bacteria
MALPKPHM_02419 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MALPKPHM_02420 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MALPKPHM_02421 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MALPKPHM_02422 7.1e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MALPKPHM_02423 1.6e-177 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MALPKPHM_02424 3.6e-188 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MALPKPHM_02426 2.8e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MALPKPHM_02427 3.6e-174
MALPKPHM_02428 2e-140
MALPKPHM_02429 9.7e-61 yitW S Iron-sulfur cluster assembly protein
MALPKPHM_02430 7.3e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MALPKPHM_02431 1.5e-272 V (ABC) transporter
MALPKPHM_02432 1.7e-310 V ABC transporter transmembrane region
MALPKPHM_02433 3.7e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MALPKPHM_02434 1.4e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
MALPKPHM_02435 3.1e-194 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MALPKPHM_02436 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MALPKPHM_02437 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MALPKPHM_02438 1.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MALPKPHM_02439 7.7e-94 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
MALPKPHM_02441 7.4e-124 V ATPases associated with a variety of cellular activities
MALPKPHM_02442 1.7e-53
MALPKPHM_02443 1.1e-147 recO L Involved in DNA repair and RecF pathway recombination
MALPKPHM_02444 9.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MALPKPHM_02445 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MALPKPHM_02446 1.5e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MALPKPHM_02447 1.5e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MALPKPHM_02448 7.7e-180 phoH T phosphate starvation-inducible protein PhoH
MALPKPHM_02449 1.6e-68 yqeY S YqeY-like protein
MALPKPHM_02450 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MALPKPHM_02451 7.2e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MALPKPHM_02452 1.2e-168 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MALPKPHM_02453 4.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MALPKPHM_02454 1.6e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MALPKPHM_02455 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MALPKPHM_02456 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
MALPKPHM_02457 5.9e-71 FG adenosine 5'-monophosphoramidase activity
MALPKPHM_02458 5.2e-248 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
MALPKPHM_02459 1.9e-115 3.1.3.18 J HAD-hyrolase-like
MALPKPHM_02460 1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MALPKPHM_02461 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MALPKPHM_02462 7.1e-11 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MALPKPHM_02463 4e-53
MALPKPHM_02464 1.1e-125 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MALPKPHM_02465 3e-173 prmA J Ribosomal protein L11 methyltransferase
MALPKPHM_02466 2.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
MALPKPHM_02467 3.2e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MALPKPHM_02468 3.1e-37
MALPKPHM_02469 3.9e-63 S Protein of unknown function (DUF1093)
MALPKPHM_02470 2.3e-26
MALPKPHM_02471 6.5e-62
MALPKPHM_02473 2.7e-111 1.6.5.2 S Flavodoxin-like fold
MALPKPHM_02474 1.2e-92 K Bacterial regulatory proteins, tetR family
MALPKPHM_02475 5.6e-186 mocA S Oxidoreductase
MALPKPHM_02476 8.5e-277 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MALPKPHM_02477 5.4e-297 2.4.1.52 GT4 M Glycosyl transferases group 1
MALPKPHM_02479 2.1e-302 2.4.1.9, 3.4.24.40 GH68 S peptidase inhibitor activity
MALPKPHM_02481 6.1e-280
MALPKPHM_02482 7.1e-61
MALPKPHM_02483 3.5e-124
MALPKPHM_02484 8.4e-190
MALPKPHM_02485 3.2e-144 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
MALPKPHM_02486 1.2e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
MALPKPHM_02487 3.7e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MALPKPHM_02488 2e-94 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MALPKPHM_02489 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MALPKPHM_02490 7.1e-62
MALPKPHM_02491 9.4e-83 6.3.3.2 S ASCH
MALPKPHM_02492 5.9e-32
MALPKPHM_02493 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MALPKPHM_02494 4.1e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MALPKPHM_02495 5.2e-286 dnaK O Heat shock 70 kDa protein
MALPKPHM_02496 1.4e-99 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MALPKPHM_02497 8.4e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MALPKPHM_02499 3.5e-224 hemN H Involved in the biosynthesis of porphyrin-containing compound
MALPKPHM_02500 6.7e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MALPKPHM_02501 4.5e-158 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MALPKPHM_02502 1.5e-141 terC P membrane
MALPKPHM_02503 4.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MALPKPHM_02504 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MALPKPHM_02505 5.4e-44 ylxQ J ribosomal protein
MALPKPHM_02506 1.5e-46 ylxR K Protein of unknown function (DUF448)
MALPKPHM_02507 7.9e-211 nusA K Participates in both transcription termination and antitermination
MALPKPHM_02508 1e-84 rimP J Required for maturation of 30S ribosomal subunits
MALPKPHM_02509 7.2e-275 L PFAM Integrase core domain
MALPKPHM_02510 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MALPKPHM_02511 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MALPKPHM_02512 4.1e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MALPKPHM_02513 4.3e-141 cdsA 2.7.7.41 S Belongs to the CDS family
MALPKPHM_02514 9.5e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MALPKPHM_02515 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MALPKPHM_02516 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MALPKPHM_02517 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MALPKPHM_02518 1.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MALPKPHM_02519 1.3e-47 yazA L GIY-YIG catalytic domain protein
MALPKPHM_02520 1.4e-133 yabB 2.1.1.223 L Methyltransferase small domain
MALPKPHM_02521 2.2e-122 plsC 2.3.1.51 I Acyltransferase
MALPKPHM_02522 7.7e-202 bcaP E Amino Acid
MALPKPHM_02523 5.8e-138 yejC S Protein of unknown function (DUF1003)
MALPKPHM_02524 0.0 mdlB V ABC transporter
MALPKPHM_02525 0.0 mdlA V ABC transporter
MALPKPHM_02526 4.8e-29 yneF S UPF0154 protein
MALPKPHM_02527 1.1e-37 ynzC S UPF0291 protein
MALPKPHM_02528 1.1e-25
MALPKPHM_02529 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MALPKPHM_02530 7.6e-146 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MALPKPHM_02531 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MALPKPHM_02532 1.4e-37 ylqC S Belongs to the UPF0109 family
MALPKPHM_02533 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MALPKPHM_02534 1.2e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MALPKPHM_02535 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MALPKPHM_02536 8.9e-24
MALPKPHM_02537 8.8e-53
MALPKPHM_02538 1.3e-182 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MALPKPHM_02539 0.0 smc D Required for chromosome condensation and partitioning
MALPKPHM_02540 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MALPKPHM_02541 0.0 oppA1 E ABC transporter substrate-binding protein
MALPKPHM_02542 8.2e-136 oppC EP Binding-protein-dependent transport system inner membrane component
MALPKPHM_02543 2.8e-174 oppB P ABC transporter permease
MALPKPHM_02544 1.2e-79 oppF P Belongs to the ABC transporter superfamily
MALPKPHM_02545 8.6e-78 oppF P Belongs to the ABC transporter superfamily
MALPKPHM_02546 2.4e-192 oppD P Belongs to the ABC transporter superfamily
MALPKPHM_02547 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MALPKPHM_02548 4e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MALPKPHM_02549 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MALPKPHM_02550 4.7e-286 yloV S DAK2 domain fusion protein YloV
MALPKPHM_02551 2.3e-57 asp S Asp23 family, cell envelope-related function
MALPKPHM_02552 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MALPKPHM_02553 2.2e-125 thiN 2.7.6.2 H thiamine pyrophosphokinase
MALPKPHM_02554 1.5e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MALPKPHM_02555 1.2e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MALPKPHM_02556 0.0 KLT serine threonine protein kinase
MALPKPHM_02557 9.7e-135 stp 3.1.3.16 T phosphatase
MALPKPHM_02558 1.3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MALPKPHM_02559 4.2e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MALPKPHM_02560 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MALPKPHM_02561 1.2e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MALPKPHM_02562 2.9e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MALPKPHM_02563 3.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MALPKPHM_02564 1.2e-118 rssA S Patatin-like phospholipase
MALPKPHM_02565 6e-51
MALPKPHM_02566 4.9e-307 recN L May be involved in recombinational repair of damaged DNA
MALPKPHM_02567 4.4e-74 argR K Regulates arginine biosynthesis genes
MALPKPHM_02568 5.2e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MALPKPHM_02569 9.7e-147 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MALPKPHM_02570 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MALPKPHM_02571 7.2e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MALPKPHM_02572 5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MALPKPHM_02573 2e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MALPKPHM_02574 1.5e-72 yqhY S Asp23 family, cell envelope-related function
MALPKPHM_02575 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MALPKPHM_02576 3.8e-201 ypdF 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MALPKPHM_02577 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MALPKPHM_02578 4.7e-55 ysxB J Cysteine protease Prp
MALPKPHM_02579 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MALPKPHM_02580 1.3e-32
MALPKPHM_02581 4.1e-14
MALPKPHM_02582 3.9e-234 ywhK S Membrane
MALPKPHM_02584 2.1e-262 V ABC transporter transmembrane region
MALPKPHM_02585 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MALPKPHM_02586 5.8e-263 glnA 6.3.1.2 E glutamine synthetase
MALPKPHM_02587 1e-60 glnR K Transcriptional regulator
MALPKPHM_02588 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MALPKPHM_02589 5.9e-241 ynbB 4.4.1.1 P aluminum resistance
MALPKPHM_02590 2.2e-179 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MALPKPHM_02591 9.8e-25 WQ51_02665 S Protein of unknown function (DUF3042)
MALPKPHM_02592 3.7e-72 yqhL P Rhodanese-like protein
MALPKPHM_02593 2e-177 glk 2.7.1.2 G Glucokinase
MALPKPHM_02594 1.1e-40 yqgQ S Bacterial protein of unknown function (DUF910)
MALPKPHM_02595 2.5e-121 gluP 3.4.21.105 S Peptidase, S54 family
MALPKPHM_02596 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MALPKPHM_02597 0.0 S Bacterial membrane protein YfhO
MALPKPHM_02598 2.9e-53 yneR S Belongs to the HesB IscA family
MALPKPHM_02599 5.8e-115 vraR K helix_turn_helix, Lux Regulon
MALPKPHM_02600 1.5e-181 vraS 2.7.13.3 T Histidine kinase
MALPKPHM_02601 2.3e-122 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MALPKPHM_02602 9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MALPKPHM_02603 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
MALPKPHM_02604 5.6e-206 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MALPKPHM_02605 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MALPKPHM_02606 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MALPKPHM_02607 6.9e-68 yodB K Transcriptional regulator, HxlR family
MALPKPHM_02608 5.6e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MALPKPHM_02609 4.8e-137 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MALPKPHM_02610 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MALPKPHM_02611 4.5e-180 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MALPKPHM_02612 1.1e-289 arlS 2.7.13.3 T Histidine kinase
MALPKPHM_02613 7.9e-123 K response regulator
MALPKPHM_02614 7.2e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MALPKPHM_02615 1.1e-95 yceD S Uncharacterized ACR, COG1399
MALPKPHM_02616 3.7e-210 ylbM S Belongs to the UPF0348 family
MALPKPHM_02617 1.1e-138 yqeM Q Methyltransferase
MALPKPHM_02618 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MALPKPHM_02619 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MALPKPHM_02620 9.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MALPKPHM_02621 1.9e-47 yhbY J RNA-binding protein
MALPKPHM_02622 6.9e-217 yqeH S Ribosome biogenesis GTPase YqeH
MALPKPHM_02623 2.4e-95 yqeG S HAD phosphatase, family IIIA
MALPKPHM_02624 3.5e-171 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MALPKPHM_02625 3.6e-190 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MALPKPHM_02626 1.8e-121 mhqD S Dienelactone hydrolase family
MALPKPHM_02627 1.6e-177 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
MALPKPHM_02628 1e-99 yvdD 3.2.2.10 S Belongs to the LOG family
MALPKPHM_02629 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MALPKPHM_02630 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MALPKPHM_02631 8.9e-78 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MALPKPHM_02632 2.6e-71 K Transcriptional regulator
MALPKPHM_02633 6.3e-233 EGP Major Facilitator Superfamily
MALPKPHM_02634 3.2e-135 cobB K Sir2 family
MALPKPHM_02635 4.8e-128 S SseB protein N-terminal domain
MALPKPHM_02636 1.6e-64
MALPKPHM_02637 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MALPKPHM_02638 6.7e-223 V regulation of methylation-dependent chromatin silencing
MALPKPHM_02639 2e-169 dnaI L Primosomal protein DnaI
MALPKPHM_02640 1.6e-249 dnaB L replication initiation and membrane attachment
MALPKPHM_02641 3.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MALPKPHM_02642 7.4e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MALPKPHM_02643 4.9e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MALPKPHM_02644 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MALPKPHM_02645 1.3e-117 ybhL S Inhibitor of apoptosis-promoting Bax1
MALPKPHM_02646 2.5e-192 S Cell surface protein
MALPKPHM_02648 3.4e-138 S WxL domain surface cell wall-binding
MALPKPHM_02649 0.0 N domain, Protein
MALPKPHM_02650 4.5e-264 K Mga helix-turn-helix domain
MALPKPHM_02651 2.2e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MALPKPHM_02652 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MALPKPHM_02654 1.2e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MALPKPHM_02655 7.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MALPKPHM_02657 4.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MALPKPHM_02658 1.2e-148 ytmP 2.7.1.89 M Choline/ethanolamine kinase
MALPKPHM_02659 2.8e-224 ecsB U ABC transporter
MALPKPHM_02660 2.2e-131 ecsA V ABC transporter, ATP-binding protein
MALPKPHM_02661 7.2e-74 hit FG histidine triad
MALPKPHM_02662 7.4e-48 yhaH S YtxH-like protein
MALPKPHM_02663 2.6e-158 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MALPKPHM_02664 9.6e-183 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
MALPKPHM_02665 4.6e-55 yheA S Control of competence regulator ComK, YlbF/YmcA
MALPKPHM_02666 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MALPKPHM_02667 1.2e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MALPKPHM_02668 5.3e-75 argR K Regulates arginine biosynthesis genes
MALPKPHM_02669 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MALPKPHM_02671 1.2e-67
MALPKPHM_02672 7.9e-22
MALPKPHM_02673 2.2e-176 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
MALPKPHM_02674 3.4e-306 glpQ 3.1.4.46 C phosphodiesterase
MALPKPHM_02675 1.1e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MALPKPHM_02676 1.5e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MALPKPHM_02677 1.8e-136 yhfI S Metallo-beta-lactamase superfamily
MALPKPHM_02678 7.6e-91 traP 1.14.99.57, 6.2.1.3 S Antibiotic biosynthesis monooxygenase
MALPKPHM_02679 0.0 V ABC transporter (permease)
MALPKPHM_02680 2.6e-138 bceA V ABC transporter
MALPKPHM_02681 9.1e-123 K response regulator
MALPKPHM_02682 5.7e-208 T PhoQ Sensor
MALPKPHM_02683 3.2e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MALPKPHM_02684 0.0 copB 3.6.3.4 P P-type ATPase
MALPKPHM_02685 6.1e-76 copR K Copper transport repressor CopY TcrY
MALPKPHM_02686 9.3e-215 purD 6.3.4.13 F Belongs to the GARS family
MALPKPHM_02687 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MALPKPHM_02688 2e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MALPKPHM_02689 5.6e-186 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MALPKPHM_02690 2.4e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MALPKPHM_02691 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MALPKPHM_02692 3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MALPKPHM_02693 6.4e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MALPKPHM_02694 2.3e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MALPKPHM_02695 2.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MALPKPHM_02696 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MALPKPHM_02697 1.8e-102 thiT S Thiamine transporter protein (Thia_YuaJ)
MALPKPHM_02699 1.4e-254 iolT EGP Major facilitator Superfamily
MALPKPHM_02700 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MALPKPHM_02701 2.7e-39 ptsH G phosphocarrier protein HPR
MALPKPHM_02702 2e-28
MALPKPHM_02703 0.0 clpE O Belongs to the ClpA ClpB family
MALPKPHM_02704 4.3e-46 XK27_09445 S Domain of unknown function (DUF1827)
MALPKPHM_02705 3.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MALPKPHM_02706 3e-243 hlyX S Transporter associated domain
MALPKPHM_02707 6.8e-207 yueF S AI-2E family transporter
MALPKPHM_02708 8.6e-75 S Acetyltransferase (GNAT) domain
MALPKPHM_02709 2.8e-96
MALPKPHM_02710 1.4e-104 ygaC J Belongs to the UPF0374 family
MALPKPHM_02711 1.8e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
MALPKPHM_02712 6.3e-290 frvR K Mga helix-turn-helix domain
MALPKPHM_02713 1e-63
MALPKPHM_02714 2.9e-254 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MALPKPHM_02715 1.3e-79 F Nucleoside 2-deoxyribosyltransferase
MALPKPHM_02716 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MALPKPHM_02717 1.2e-219 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MALPKPHM_02718 2.3e-213 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
MALPKPHM_02719 4.2e-209 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
MALPKPHM_02720 3.6e-48
MALPKPHM_02721 8.8e-161 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
MALPKPHM_02722 1.8e-101 V Restriction endonuclease
MALPKPHM_02723 4.8e-159 5.1.3.3 G Aldose 1-epimerase
MALPKPHM_02724 4.4e-211 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MALPKPHM_02725 4.4e-101 S ECF transporter, substrate-specific component
MALPKPHM_02727 4.3e-80 yodP 2.3.1.264 K FR47-like protein
MALPKPHM_02728 5.2e-83 ydcK S Belongs to the SprT family
MALPKPHM_02729 2.8e-129 XK27_08845 S ABC transporter, ATP-binding protein
MALPKPHM_02730 2.5e-129 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MALPKPHM_02731 6.8e-176 XK27_08835 S ABC transporter
MALPKPHM_02732 6.9e-72
MALPKPHM_02733 0.0 pacL 3.6.3.8 P P-type ATPase
MALPKPHM_02734 1.3e-215 V Beta-lactamase
MALPKPHM_02735 4.8e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MALPKPHM_02736 3.7e-221 V Beta-lactamase
MALPKPHM_02737 2.3e-273 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MALPKPHM_02738 6.6e-125 gntR1 K UbiC transcription regulator-associated domain protein
MALPKPHM_02739 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MALPKPHM_02740 1.1e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MALPKPHM_02741 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
MALPKPHM_02742 2.6e-200 sprD D Domain of Unknown Function (DUF1542)
MALPKPHM_02743 4.6e-261 mga K Mga helix-turn-helix domain
MALPKPHM_02745 1.5e-155 yjjH S Calcineurin-like phosphoesterase
MALPKPHM_02746 4e-257 dtpT U amino acid peptide transporter
MALPKPHM_02747 0.0 macB_3 V ABC transporter, ATP-binding protein
MALPKPHM_02748 1.4e-65
MALPKPHM_02749 2.7e-16 S function, without similarity to other proteins
MALPKPHM_02750 1.7e-260 G MFS/sugar transport protein
MALPKPHM_02751 2.5e-230 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
MALPKPHM_02752 1e-56
MALPKPHM_02753 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
MALPKPHM_02754 1.6e-24 S Virus attachment protein p12 family
MALPKPHM_02755 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MALPKPHM_02756 1.7e-82 feoA P FeoA
MALPKPHM_02757 4.5e-119 E lipolytic protein G-D-S-L family
MALPKPHM_02758 1e-81 E AAA domain
MALPKPHM_02761 2.9e-119 ywnB S NAD(P)H-binding
MALPKPHM_02762 8.7e-92 S MucBP domain
MALPKPHM_02763 1.3e-85
MALPKPHM_02765 8.9e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)