ORF_ID e_value Gene_name EC_number CAZy COGs Description
EHHHJOPM_00001 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EHHHJOPM_00002 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EHHHJOPM_00003 1.3e-108 jag S single-stranded nucleic acid binding R3H
EHHHJOPM_00004 2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHHHJOPM_00005 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EHHHJOPM_00006 7.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EHHHJOPM_00007 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EHHHJOPM_00008 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
EHHHJOPM_00009 1.5e-147 spo0J K Belongs to the ParB family
EHHHJOPM_00010 6.2e-111 yyaC S Sporulation protein YyaC
EHHHJOPM_00011 1.1e-40 4.2.1.103 K FR47-like protein
EHHHJOPM_00012 2.4e-176 yyaD S Membrane
EHHHJOPM_00013 2.3e-33 yyzM S protein conserved in bacteria
EHHHJOPM_00014 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHHHJOPM_00015 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EHHHJOPM_00016 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
EHHHJOPM_00017 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EHHHJOPM_00018 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EHHHJOPM_00019 4.8e-105 adaA 3.2.2.21 K Transcriptional regulator
EHHHJOPM_00020 2.7e-97 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHHHJOPM_00021 7.8e-140 xth 3.1.11.2 L exodeoxyribonuclease III
EHHHJOPM_00022 1.2e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
EHHHJOPM_00023 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHHJOPM_00024 5.8e-247 ydjK G Sugar (and other) transporter
EHHHJOPM_00025 9.5e-161 yyaK S CAAX protease self-immunity
EHHHJOPM_00026 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
EHHHJOPM_00027 2.1e-40 qacC U Small Multidrug Resistance protein
EHHHJOPM_00028 7.6e-14 yvaO K Transcriptional
EHHHJOPM_00029 3.3e-78 K Transcriptional regulator
EHHHJOPM_00030 4.3e-99 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHHHJOPM_00031 3.6e-131 ydfC EG EamA-like transporter family
EHHHJOPM_00032 2.7e-250 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHHHJOPM_00033 3.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EHHHJOPM_00034 2.5e-161 K Transcriptional regulator
EHHHJOPM_00035 1.7e-64 4.1.1.44 S Carboxymuconolactone decarboxylase family
EHHHJOPM_00036 6.4e-162 eaeH M Domain of Unknown Function (DUF1259)
EHHHJOPM_00037 2.8e-91
EHHHJOPM_00038 8.9e-61 lysR K LysR substrate binding domain
EHHHJOPM_00039 1.6e-76 yybA 2.3.1.57 K transcriptional
EHHHJOPM_00040 1e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EHHHJOPM_00041 4.1e-69 ydgJ K Winged helix DNA-binding domain
EHHHJOPM_00042 1.6e-114 drgA C nitroreductase
EHHHJOPM_00043 2.2e-55 ypaA S Protein of unknown function (DUF1304)
EHHHJOPM_00044 5.4e-159 G Major Facilitator Superfamily
EHHHJOPM_00045 5.2e-71 dinB S PFAM DinB family protein
EHHHJOPM_00046 2.2e-114 K FCD domain
EHHHJOPM_00047 1.5e-310 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
EHHHJOPM_00048 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
EHHHJOPM_00049 1.2e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EHHHJOPM_00050 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
EHHHJOPM_00051 8.2e-66 ydeP3 K Transcriptional regulator
EHHHJOPM_00052 6.1e-83 cotF M Spore coat protein
EHHHJOPM_00054 2.4e-159 yybS S membrane
EHHHJOPM_00055 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EHHHJOPM_00056 4.9e-73 rplI J binds to the 23S rRNA
EHHHJOPM_00057 8.2e-102 KLT COG0515 Serine threonine protein kinase
EHHHJOPM_00058 2.7e-120 S GlcNAc-PI de-N-acetylase
EHHHJOPM_00059 5.1e-243 M Glycosyltransferase Family 4
EHHHJOPM_00060 2.5e-233 S Carbamoyl-phosphate synthase L chain, ATP binding domain
EHHHJOPM_00061 6.9e-203 S Ecdysteroid kinase
EHHHJOPM_00062 1.4e-234 M Glycosyltransferase Family 4
EHHHJOPM_00063 4.6e-17 yycC K YycC-like protein
EHHHJOPM_00065 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
EHHHJOPM_00066 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EHHHJOPM_00067 8.5e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHHJOPM_00068 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHHHJOPM_00073 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHHJOPM_00074 0.0 vicK 2.7.13.3 T Histidine kinase
EHHHJOPM_00075 2.5e-261 yycH S protein conserved in bacteria
EHHHJOPM_00076 1.1e-150 yycI S protein conserved in bacteria
EHHHJOPM_00077 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EHHHJOPM_00078 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHHHJOPM_00079 2.1e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHHJOPM_00080 2.5e-248 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
EHHHJOPM_00081 3.9e-187 2.7.7.73, 2.7.7.80 H ThiF family
EHHHJOPM_00082 8e-257
EHHHJOPM_00083 4.4e-198 S Major Facilitator Superfamily
EHHHJOPM_00084 1.8e-303 S ABC transporter
EHHHJOPM_00085 5.9e-145 1.14.11.27 P peptidyl-arginine hydroxylation
EHHHJOPM_00086 7.7e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EHHHJOPM_00087 2.2e-42 sdpR K transcriptional
EHHHJOPM_00088 4.2e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
EHHHJOPM_00089 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
EHHHJOPM_00090 1.1e-256 rocE E amino acid
EHHHJOPM_00091 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
EHHHJOPM_00092 1.1e-198 S Histidine kinase
EHHHJOPM_00094 9e-86 yycN 2.3.1.128 K Acetyltransferase
EHHHJOPM_00095 3.3e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
EHHHJOPM_00096 4.5e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EHHHJOPM_00097 6.2e-213 yycP
EHHHJOPM_00099 7.9e-08 S YyzF-like protein
EHHHJOPM_00100 7.5e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHHHJOPM_00101 3e-13 tnp L transposase activity
EHHHJOPM_00102 9.9e-200 3.6.4.12 KL HELICc2
EHHHJOPM_00103 9.7e-134 L Molecular Function DNA binding, Biological Process DNA recombination
EHHHJOPM_00104 1.8e-39 L COG2963 Transposase and inactivated derivatives
EHHHJOPM_00105 6.8e-42 S MazG-like family
EHHHJOPM_00106 1.1e-244 L Uncharacterized conserved protein (DUF2075)
EHHHJOPM_00107 3.2e-157 L AAA domain
EHHHJOPM_00108 6.8e-139 L AAA domain
EHHHJOPM_00109 2e-173 S Fusaric acid resistance protein-like
EHHHJOPM_00110 6.9e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EHHHJOPM_00111 7.4e-88 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
EHHHJOPM_00112 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EHHHJOPM_00113 4.7e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EHHHJOPM_00114 5.9e-82 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EHHHJOPM_00115 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
EHHHJOPM_00116 7.9e-244 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
EHHHJOPM_00117 2.3e-287 ahpF O Alkyl hydroperoxide reductase
EHHHJOPM_00118 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
EHHHJOPM_00119 3.2e-124 E Ring-cleavage extradiol dioxygenase
EHHHJOPM_00120 7.6e-74 yxaI S membrane protein domain
EHHHJOPM_00121 1.9e-201 EGP Major facilitator Superfamily
EHHHJOPM_00122 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
EHHHJOPM_00123 1e-64 S Family of unknown function (DUF5391)
EHHHJOPM_00124 2.8e-142 S PQQ-like domain
EHHHJOPM_00125 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EHHHJOPM_00126 1.2e-213 yxbF K Bacterial regulatory proteins, tetR family
EHHHJOPM_00127 1.8e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
EHHHJOPM_00128 1.7e-199 desK 2.7.13.3 T Histidine kinase
EHHHJOPM_00129 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHHJOPM_00130 4.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
EHHHJOPM_00132 0.0 htpG O Molecular chaperone. Has ATPase activity
EHHHJOPM_00133 1.9e-245 csbC EGP Major facilitator Superfamily
EHHHJOPM_00134 1.2e-174 iolS C Aldo keto reductase
EHHHJOPM_00135 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
EHHHJOPM_00136 1.8e-278 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHHHJOPM_00137 1.6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EHHHJOPM_00138 3.8e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EHHHJOPM_00139 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EHHHJOPM_00140 2e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EHHHJOPM_00141 5.1e-232 iolF EGP Major facilitator Superfamily
EHHHJOPM_00142 5.8e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EHHHJOPM_00143 3.3e-166 iolH G Xylose isomerase-like TIM barrel
EHHHJOPM_00144 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EHHHJOPM_00145 1.8e-156 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EHHHJOPM_00146 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHHJOPM_00147 3.5e-177 T PhoQ Sensor
EHHHJOPM_00148 3.6e-140 yxdL V ABC transporter, ATP-binding protein
EHHHJOPM_00149 0.0 yxdM V ABC transporter (permease)
EHHHJOPM_00150 1.3e-57 yxeA S Protein of unknown function (DUF1093)
EHHHJOPM_00151 4.1e-178 fhuD P Periplasmic binding protein
EHHHJOPM_00152 1.3e-34
EHHHJOPM_00153 8.4e-23 yxeD
EHHHJOPM_00157 2.6e-149 yidA S hydrolases of the HAD superfamily
EHHHJOPM_00158 9.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EHHHJOPM_00159 3.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHHHJOPM_00160 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHHHJOPM_00161 2.5e-231 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
EHHHJOPM_00162 4.4e-253 lysP E amino acid
EHHHJOPM_00163 4.7e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EHHHJOPM_00164 1.7e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
EHHHJOPM_00165 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EHHHJOPM_00166 1.1e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
EHHHJOPM_00167 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EHHHJOPM_00168 2e-274 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EHHHJOPM_00169 5.5e-65 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EHHHJOPM_00170 0.0 L HKD family nuclease
EHHHJOPM_00171 1.8e-72 yxiE T Belongs to the universal stress protein A family
EHHHJOPM_00172 6.1e-147 yxxF EG EamA-like transporter family
EHHHJOPM_00173 1.2e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
EHHHJOPM_00174 1.4e-45 yxxG
EHHHJOPM_00175 8.6e-69 yxiG
EHHHJOPM_00179 2.8e-32
EHHHJOPM_00180 5.2e-78
EHHHJOPM_00182 1.1e-14 S YxiJ-like protein
EHHHJOPM_00183 4.2e-22
EHHHJOPM_00184 1.6e-48 yxiI S Protein of unknown function (DUF2716)
EHHHJOPM_00185 1.2e-61 S SMI1-KNR4 cell-wall
EHHHJOPM_00188 3.4e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EHHHJOPM_00189 3.7e-219 yxiO S COG2270 Permeases of the major facilitator superfamily
EHHHJOPM_00190 4.1e-21 licT K transcriptional antiterminator
EHHHJOPM_00191 1.4e-55 licT K transcriptional antiterminator
EHHHJOPM_00192 2e-140 exoK GH16 M licheninase activity
EHHHJOPM_00193 1.4e-221 citH C Citrate transporter
EHHHJOPM_00194 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
EHHHJOPM_00195 4.3e-49 yxiS
EHHHJOPM_00196 1.8e-71 T Domain of unknown function (DUF4163)
EHHHJOPM_00197 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHHHJOPM_00198 4.5e-155 rlmA 2.1.1.187 Q Methyltransferase domain
EHHHJOPM_00199 1.8e-217 yxjG 2.1.1.14 E Methionine synthase
EHHHJOPM_00200 2e-85 yxjI S LURP-one-related
EHHHJOPM_00203 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EHHHJOPM_00204 2.4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EHHHJOPM_00205 3.8e-87 yxkC S Domain of unknown function (DUF4352)
EHHHJOPM_00206 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHHHJOPM_00207 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
EHHHJOPM_00208 2.6e-205 msmK P Belongs to the ABC transporter superfamily
EHHHJOPM_00209 9.6e-155 yxkH G Polysaccharide deacetylase
EHHHJOPM_00210 1e-214 cimH C COG3493 Na citrate symporter
EHHHJOPM_00211 4.5e-266 cydA 1.10.3.14 C oxidase, subunit
EHHHJOPM_00212 1.1e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
EHHHJOPM_00213 2.4e-311 cydD V ATP-binding
EHHHJOPM_00214 8.5e-291 cydD V ATP-binding protein
EHHHJOPM_00215 6.5e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHHHJOPM_00216 1e-251 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
EHHHJOPM_00217 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
EHHHJOPM_00218 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EHHHJOPM_00219 2.1e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
EHHHJOPM_00220 1.8e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
EHHHJOPM_00221 1.8e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
EHHHJOPM_00222 4e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EHHHJOPM_00223 1.6e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHHHJOPM_00224 8.6e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
EHHHJOPM_00225 1.3e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
EHHHJOPM_00226 6.5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EHHHJOPM_00227 1.7e-57 arsR K transcriptional
EHHHJOPM_00228 1.5e-166 cbrA3 P Periplasmic binding protein
EHHHJOPM_00229 7.9e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHHJOPM_00230 2.8e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHHJOPM_00231 7.8e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
EHHHJOPM_00232 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
EHHHJOPM_00233 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
EHHHJOPM_00234 7.4e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHHHJOPM_00235 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
EHHHJOPM_00236 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EHHHJOPM_00237 1.9e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EHHHJOPM_00238 3.1e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EHHHJOPM_00239 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_00240 4.8e-229 dltB M membrane protein involved in D-alanine export
EHHHJOPM_00241 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_00242 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
EHHHJOPM_00243 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
EHHHJOPM_00244 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
EHHHJOPM_00245 4.1e-161 gspA M General stress
EHHHJOPM_00246 1.1e-261 epr 3.4.21.62 O Belongs to the peptidase S8 family
EHHHJOPM_00247 7.1e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHHHJOPM_00248 7.6e-67 ywbC 4.4.1.5 E glyoxalase
EHHHJOPM_00249 1e-223 ywbD 2.1.1.191 J Methyltransferase
EHHHJOPM_00250 2.5e-138 mta K transcriptional
EHHHJOPM_00251 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
EHHHJOPM_00252 2.2e-109 ywbG M effector of murein hydrolase
EHHHJOPM_00253 4.2e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EHHHJOPM_00254 8.2e-152 ywbI K Transcriptional regulator
EHHHJOPM_00255 3.1e-134 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHHHJOPM_00256 6.6e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EHHHJOPM_00257 1.1e-242 ywbN P Dyp-type peroxidase family protein
EHHHJOPM_00258 1.1e-109 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EHHHJOPM_00259 2.2e-130 S Streptomycin biosynthesis protein StrF
EHHHJOPM_00260 7.3e-129 H Methionine biosynthesis protein MetW
EHHHJOPM_00262 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
EHHHJOPM_00263 5.1e-61 gtcA S GtrA-like protein
EHHHJOPM_00264 3.9e-295 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EHHHJOPM_00265 8.4e-27 ywzA S membrane
EHHHJOPM_00266 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EHHHJOPM_00267 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHHHJOPM_00268 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EHHHJOPM_00269 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
EHHHJOPM_00270 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
EHHHJOPM_00271 1.7e-76 ysnE K acetyltransferase
EHHHJOPM_00272 8e-208 rodA D Belongs to the SEDS family
EHHHJOPM_00273 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
EHHHJOPM_00274 1.1e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHHJOPM_00275 0.0 vpr O Belongs to the peptidase S8 family
EHHHJOPM_00277 2.8e-151 sacT K transcriptional antiterminator
EHHHJOPM_00278 9.9e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EHHHJOPM_00279 3.2e-283 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
EHHHJOPM_00280 7.4e-20 ywdA
EHHHJOPM_00281 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EHHHJOPM_00282 6.3e-57 pex K Transcriptional regulator PadR-like family
EHHHJOPM_00283 5.8e-88 ywdD
EHHHJOPM_00285 1.8e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
EHHHJOPM_00286 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHHHJOPM_00287 4.7e-41 ywdI S Family of unknown function (DUF5327)
EHHHJOPM_00288 5.4e-229 ywdJ F Xanthine uracil
EHHHJOPM_00289 4.2e-46 ywdK S small membrane protein
EHHHJOPM_00290 7.1e-60 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EHHHJOPM_00291 3.8e-142 spsA M Spore Coat
EHHHJOPM_00292 9.1e-275 spsB M Capsule polysaccharide biosynthesis protein
EHHHJOPM_00293 4e-220 spsC E Belongs to the DegT DnrJ EryC1 family
EHHHJOPM_00294 1.2e-155 spsD 2.3.1.210 K Spore Coat
EHHHJOPM_00295 2.4e-214 spsE 2.5.1.56 M acid synthase
EHHHJOPM_00296 2.6e-132 spsF M Spore Coat
EHHHJOPM_00297 5.6e-178 spsG M Spore Coat
EHHHJOPM_00298 1.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EHHHJOPM_00299 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EHHHJOPM_00300 1.2e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EHHHJOPM_00301 3e-86 spsL 5.1.3.13 M Spore Coat
EHHHJOPM_00302 1.9e-59
EHHHJOPM_00303 7.3e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EHHHJOPM_00304 8.6e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EHHHJOPM_00305 0.0 rocB E arginine degradation protein
EHHHJOPM_00306 2.7e-258 lysP E amino acid
EHHHJOPM_00307 4.9e-205 tcaB EGP Major facilitator Superfamily
EHHHJOPM_00308 7.8e-222 ywfA EGP Major facilitator Superfamily
EHHHJOPM_00309 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EHHHJOPM_00310 7.6e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EHHHJOPM_00311 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHHJOPM_00312 2.4e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EHHHJOPM_00313 1e-207 bacE EGP Major facilitator Superfamily
EHHHJOPM_00314 9.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
EHHHJOPM_00315 1.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
EHHHJOPM_00316 1.1e-146 ywfI C May function as heme-dependent peroxidase
EHHHJOPM_00317 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
EHHHJOPM_00318 6.2e-158 MA20_14895 S Conserved hypothetical protein 698
EHHHJOPM_00319 3e-162 cysL K Transcriptional regulator
EHHHJOPM_00320 9.5e-158 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EHHHJOPM_00321 2.1e-40 V ABC transporter, ATP-binding protein
EHHHJOPM_00322 1.1e-93 S membrane
EHHHJOPM_00323 9.7e-52 padR K PadR family transcriptional regulator
EHHHJOPM_00324 6.6e-110 rsfA_1
EHHHJOPM_00325 6.9e-36 ywzC S Belongs to the UPF0741 family
EHHHJOPM_00326 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
EHHHJOPM_00327 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
EHHHJOPM_00328 1.9e-245 yhdG_1 E C-terminus of AA_permease
EHHHJOPM_00329 4.9e-67 ywhA K Transcriptional regulator
EHHHJOPM_00330 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
EHHHJOPM_00331 1.2e-117 ywhC S Peptidase family M50
EHHHJOPM_00332 6.4e-93 ywhD S YwhD family
EHHHJOPM_00333 8e-81
EHHHJOPM_00334 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EHHHJOPM_00335 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EHHHJOPM_00336 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
EHHHJOPM_00339 9.9e-75 CP Membrane
EHHHJOPM_00341 3.6e-31
EHHHJOPM_00342 9.7e-29 ydcG K sequence-specific DNA binding
EHHHJOPM_00344 2.9e-77 S aspartate phosphatase
EHHHJOPM_00345 2.9e-43 ywiB S protein conserved in bacteria
EHHHJOPM_00346 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EHHHJOPM_00347 2.7e-211 narK P COG2223 Nitrate nitrite transporter
EHHHJOPM_00348 5e-128 fnr K helix_turn_helix, cAMP Regulatory protein
EHHHJOPM_00349 9.1e-138 ywiC S YwiC-like protein
EHHHJOPM_00350 1.7e-84 arfM T cyclic nucleotide binding
EHHHJOPM_00351 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHHHJOPM_00352 1.8e-294 narH 1.7.5.1 C Nitrate reductase, beta
EHHHJOPM_00353 7.9e-89 narJ 1.7.5.1 C nitrate reductase
EHHHJOPM_00354 6.1e-120 narI 1.7.5.1 C nitrate reductase, gamma
EHHHJOPM_00355 3.4e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHHHJOPM_00356 7.9e-296 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHHHJOPM_00357 0.0 ywjA V ABC transporter
EHHHJOPM_00358 4.2e-43 ywjC
EHHHJOPM_00359 1.3e-179 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EHHHJOPM_00360 1.1e-217 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EHHHJOPM_00361 0.0 fadF C COG0247 Fe-S oxidoreductase
EHHHJOPM_00362 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EHHHJOPM_00363 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EHHHJOPM_00364 2.4e-92 ywjG S Domain of unknown function (DUF2529)
EHHHJOPM_00365 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
EHHHJOPM_00366 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
EHHHJOPM_00367 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHHHJOPM_00368 1.2e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHHHJOPM_00369 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
EHHHJOPM_00370 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHHHJOPM_00371 1.1e-32 rpmE J Binds the 23S rRNA
EHHHJOPM_00372 1.1e-101 tdk 2.7.1.21 F thymidine kinase
EHHHJOPM_00373 0.0 sfcA 1.1.1.38 C malic enzyme
EHHHJOPM_00374 6.8e-157 ywkB S Membrane transport protein
EHHHJOPM_00375 7e-93 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EHHHJOPM_00376 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHHJOPM_00377 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHHHJOPM_00378 4.8e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EHHHJOPM_00380 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
EHHHJOPM_00381 8.9e-119 spoIIR S stage II sporulation protein R
EHHHJOPM_00382 1.1e-74 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
EHHHJOPM_00383 1.5e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EHHHJOPM_00384 1.3e-83 mntP P Probably functions as a manganese efflux pump
EHHHJOPM_00385 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHHHJOPM_00386 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
EHHHJOPM_00387 1.7e-96 ywlG S Belongs to the UPF0340 family
EHHHJOPM_00388 5.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHHHJOPM_00389 2.3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHHHJOPM_00390 2.1e-61 atpI S ATP synthase
EHHHJOPM_00391 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
EHHHJOPM_00392 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHHHJOPM_00393 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EHHHJOPM_00394 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHHHJOPM_00395 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHHHJOPM_00396 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHHHJOPM_00397 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHHHJOPM_00398 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EHHHJOPM_00399 8.7e-89 ywmA
EHHHJOPM_00400 4.8e-32 ywzB S membrane
EHHHJOPM_00401 2.2e-134 ywmB S TATA-box binding
EHHHJOPM_00402 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHHHJOPM_00403 4e-179 spoIID D Stage II sporulation protein D
EHHHJOPM_00404 5.1e-114 ywmC S protein containing a von Willebrand factor type A (vWA) domain
EHHHJOPM_00405 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
EHHHJOPM_00407 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHHHJOPM_00408 1.6e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHHHJOPM_00409 2.8e-93 S response regulator aspartate phosphatase
EHHHJOPM_00410 2.3e-81 ywmF S Peptidase M50
EHHHJOPM_00411 1.4e-10 csbD K CsbD-like
EHHHJOPM_00412 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EHHHJOPM_00413 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EHHHJOPM_00414 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EHHHJOPM_00415 1.8e-66 ywnA K Transcriptional regulator
EHHHJOPM_00417 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
EHHHJOPM_00418 1.2e-51 ywnC S Family of unknown function (DUF5362)
EHHHJOPM_00419 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHHHJOPM_00420 4.2e-69 ywnF S Family of unknown function (DUF5392)
EHHHJOPM_00421 1.2e-10 ywnC S Family of unknown function (DUF5362)
EHHHJOPM_00422 4.9e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
EHHHJOPM_00423 1.3e-119 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
EHHHJOPM_00424 2.1e-70 ywnJ S VanZ like family
EHHHJOPM_00425 4.6e-100 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
EHHHJOPM_00426 5.1e-207 ftsW D Belongs to the SEDS family
EHHHJOPM_00427 2e-58 nrgB K Belongs to the P(II) protein family
EHHHJOPM_00428 2.5e-228 amt P Ammonium transporter
EHHHJOPM_00429 2.8e-102 phzA Q Isochorismatase family
EHHHJOPM_00430 1.6e-244 ywoD EGP Major facilitator superfamily
EHHHJOPM_00431 1.1e-275 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
EHHHJOPM_00432 4.1e-212 ywoG EGP Major facilitator Superfamily
EHHHJOPM_00433 2.5e-71 ywoH K transcriptional
EHHHJOPM_00434 1.8e-44 spoIIID K Stage III sporulation protein D
EHHHJOPM_00435 2.7e-180 mbl D Rod shape-determining protein
EHHHJOPM_00436 4.2e-128 flhO N flagellar basal body
EHHHJOPM_00437 7e-142 flhP N flagellar basal body
EHHHJOPM_00438 5.2e-198 S aspartate phosphatase
EHHHJOPM_00439 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EHHHJOPM_00440 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EHHHJOPM_00441 2.5e-68 ywpF S YwpF-like protein
EHHHJOPM_00442 4e-62 ywpG
EHHHJOPM_00443 3.7e-57 ssbB L Single-stranded DNA-binding protein
EHHHJOPM_00444 7.5e-138 glcR K DeoR C terminal sensor domain
EHHHJOPM_00445 1.7e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
EHHHJOPM_00446 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EHHHJOPM_00447 1.6e-307 ywqB S SWIM zinc finger
EHHHJOPM_00448 1.3e-14
EHHHJOPM_00449 4.1e-109 ywqC M biosynthesis protein
EHHHJOPM_00450 1.6e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
EHHHJOPM_00451 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
EHHHJOPM_00452 1.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHHHJOPM_00453 1.3e-145 ywqG S Domain of unknown function (DUF1963)
EHHHJOPM_00454 1.4e-21 S Domain of unknown function (DUF5082)
EHHHJOPM_00455 4.3e-37 ywqI S Family of unknown function (DUF5344)
EHHHJOPM_00456 2.4e-301 ywqJ S Pre-toxin TG
EHHHJOPM_00457 2.6e-49
EHHHJOPM_00458 2.4e-41 S Protein of unknown function (DUF2004)
EHHHJOPM_00459 1.1e-87 ywqJ S Pre-toxin TG
EHHHJOPM_00460 4.3e-66 S SMI1 / KNR4 family (SUKH-1)
EHHHJOPM_00461 8.4e-16 S SMI1 / KNR4 family
EHHHJOPM_00462 1.7e-90
EHHHJOPM_00463 1.6e-131 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
EHHHJOPM_00464 9e-156 K Transcriptional regulator
EHHHJOPM_00465 1.7e-91 ywqN S NAD(P)H-dependent
EHHHJOPM_00467 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
EHHHJOPM_00468 9.5e-101 ywrB P Chromate transporter
EHHHJOPM_00469 2.5e-83 ywrC K Transcriptional regulator
EHHHJOPM_00470 6.5e-298 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EHHHJOPM_00472 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EHHHJOPM_00473 1.3e-09
EHHHJOPM_00474 3.2e-211 cotH M Spore Coat
EHHHJOPM_00475 6e-131 cotB
EHHHJOPM_00476 4.4e-126 ywrJ
EHHHJOPM_00477 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EHHHJOPM_00479 2.6e-166 alsR K LysR substrate binding domain
EHHHJOPM_00480 2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EHHHJOPM_00481 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
EHHHJOPM_00482 5.3e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
EHHHJOPM_00483 3.4e-89 batE T Sh3 type 3 domain protein
EHHHJOPM_00484 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
EHHHJOPM_00485 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
EHHHJOPM_00486 2.4e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EHHHJOPM_00487 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EHHHJOPM_00488 3.1e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHHHJOPM_00489 3.2e-178 rbsR K transcriptional
EHHHJOPM_00490 1.5e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
EHHHJOPM_00491 3.1e-190 gerKB E Spore germination protein
EHHHJOPM_00492 4.5e-184 gerKA EG Spore germination protein
EHHHJOPM_00493 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
EHHHJOPM_00494 2.3e-70 pgsC S biosynthesis protein
EHHHJOPM_00495 2.8e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EHHHJOPM_00496 1.3e-20 ywtC
EHHHJOPM_00497 6.6e-237 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EHHHJOPM_00498 5.5e-34 yttA 2.7.13.3 S Pfam Transposase IS66
EHHHJOPM_00499 1.8e-156 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
EHHHJOPM_00500 7.2e-178 ywtF K Transcriptional regulator
EHHHJOPM_00501 4.9e-249 ywtG EGP Major facilitator Superfamily
EHHHJOPM_00502 1.5e-266 GT2,GT4 J Glycosyl transferase family 2
EHHHJOPM_00503 1.1e-209 gerAC S Spore germination protein
EHHHJOPM_00504 7.8e-197 gerBB E Spore germination protein
EHHHJOPM_00505 2.8e-263 gerBA EG Spore germination protein
EHHHJOPM_00506 7.7e-185 pmi 5.3.1.8 G mannose-6-phosphate isomerase
EHHHJOPM_00507 2.3e-239 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EHHHJOPM_00508 5.5e-217 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHHHJOPM_00509 1.4e-141 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EHHHJOPM_00510 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
EHHHJOPM_00511 8.6e-279 M Glycosyltransferase like family 2
EHHHJOPM_00512 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EHHHJOPM_00513 1.7e-151 tagG GM Transport permease protein
EHHHJOPM_00514 1.1e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EHHHJOPM_00515 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EHHHJOPM_00516 4.5e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EHHHJOPM_00517 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EHHHJOPM_00518 2.3e-48
EHHHJOPM_00519 0.0 lytB 3.5.1.28 D Stage II sporulation protein
EHHHJOPM_00520 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EHHHJOPM_00521 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EHHHJOPM_00522 6.1e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHHJOPM_00523 2.6e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
EHHHJOPM_00524 3.4e-247 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHHHJOPM_00525 5.2e-254 tuaE M Teichuronic acid biosynthesis protein
EHHHJOPM_00526 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
EHHHJOPM_00527 3.4e-143 tuaG GT2 M Glycosyltransferase like family 2
EHHHJOPM_00528 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
EHHHJOPM_00529 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EHHHJOPM_00530 2.3e-165 yvhJ K Transcriptional regulator
EHHHJOPM_00531 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
EHHHJOPM_00532 1.4e-180 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EHHHJOPM_00533 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHHJOPM_00534 1.4e-158 degV S protein conserved in bacteria
EHHHJOPM_00535 7.1e-256 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EHHHJOPM_00536 1.7e-42 comFB S Late competence development protein ComFB
EHHHJOPM_00537 4.6e-68 comFC S Phosphoribosyl transferase domain
EHHHJOPM_00538 4.1e-74 yvyF S flagellar protein
EHHHJOPM_00539 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
EHHHJOPM_00540 8.9e-81 flgN NOU FlgN protein
EHHHJOPM_00541 1.8e-273 flgK N flagellar hook-associated protein
EHHHJOPM_00542 2.3e-162 flgL N Belongs to the bacterial flagellin family
EHHHJOPM_00543 1.2e-79 yviE
EHHHJOPM_00544 7.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EHHHJOPM_00545 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EHHHJOPM_00546 7.1e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHHHJOPM_00547 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHHHJOPM_00548 3e-66 fliS N flagellar protein FliS
EHHHJOPM_00549 4.5e-10 fliT S bacterial-type flagellum organization
EHHHJOPM_00550 6.8e-68
EHHHJOPM_00551 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHHHJOPM_00552 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EHHHJOPM_00553 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EHHHJOPM_00554 3e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
EHHHJOPM_00555 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
EHHHJOPM_00556 2.3e-122 ftsE D cell division ATP-binding protein FtsE
EHHHJOPM_00557 1.2e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EHHHJOPM_00558 8.6e-225 ywoF P Right handed beta helix region
EHHHJOPM_00559 1.1e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
EHHHJOPM_00560 1.5e-55 swrA S Swarming motility protein
EHHHJOPM_00561 8.3e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHHHJOPM_00562 4e-174 S Psort location CytoplasmicMembrane, score
EHHHJOPM_00564 2.6e-14 bacT Q Thioesterase domain
EHHHJOPM_00565 2.3e-52 L For insertion sequence element IS256 in transposon Tn4001
EHHHJOPM_00566 2.2e-08 L Transposase, Mutator family
EHHHJOPM_00567 5.6e-226 yvkA EGP Major facilitator Superfamily
EHHHJOPM_00568 1.7e-108 yvkB K Transcriptional regulator
EHHHJOPM_00569 0.0 yvkC 2.7.9.2 GT Phosphotransferase
EHHHJOPM_00570 7.6e-33 csbA S protein conserved in bacteria
EHHHJOPM_00571 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EHHHJOPM_00572 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EHHHJOPM_00573 2.2e-32 yvkN
EHHHJOPM_00574 6.1e-49 yvlA
EHHHJOPM_00575 1.2e-165 yvlB S Putative adhesin
EHHHJOPM_00576 9.6e-26 pspB KT PspC domain
EHHHJOPM_00577 1.5e-40 yvlD S Membrane
EHHHJOPM_00578 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
EHHHJOPM_00579 4.4e-103 yxaF K Transcriptional regulator
EHHHJOPM_00580 2.3e-133 yvoA K transcriptional
EHHHJOPM_00581 3.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EHHHJOPM_00582 1e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHHHJOPM_00583 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EHHHJOPM_00584 5.8e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHHHJOPM_00585 1.4e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EHHHJOPM_00586 2.4e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
EHHHJOPM_00587 3.5e-137 yvpB NU protein conserved in bacteria
EHHHJOPM_00588 1.1e-206 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EHHHJOPM_00589 5.6e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EHHHJOPM_00590 1.4e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHHHJOPM_00591 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EHHHJOPM_00592 1.5e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHHHJOPM_00593 6e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHHHJOPM_00594 4.9e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EHHHJOPM_00595 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
EHHHJOPM_00596 0.0 msbA2 3.6.3.44 V ABC transporter
EHHHJOPM_00597 1.1e-54
EHHHJOPM_00598 9.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHHJOPM_00599 4e-190 sasA T Histidine kinase
EHHHJOPM_00600 2.5e-275 S COG0457 FOG TPR repeat
EHHHJOPM_00601 1.3e-124 usp CBM50 M protein conserved in bacteria
EHHHJOPM_00602 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EHHHJOPM_00603 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EHHHJOPM_00604 1.1e-166 rapZ S Displays ATPase and GTPase activities
EHHHJOPM_00605 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EHHHJOPM_00606 3.1e-170 whiA K May be required for sporulation
EHHHJOPM_00607 4.7e-36 crh G Phosphocarrier protein Chr
EHHHJOPM_00608 5.7e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
EHHHJOPM_00609 4.8e-79 M Ribonuclease
EHHHJOPM_00610 1.5e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHHHJOPM_00611 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EHHHJOPM_00612 9.5e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
EHHHJOPM_00613 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
EHHHJOPM_00614 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
EHHHJOPM_00615 5.3e-11 yvdD 3.2.2.10 S Belongs to the LOG family
EHHHJOPM_00616 2.1e-247 EGP Sugar (and other) transporter
EHHHJOPM_00617 6.9e-209 yraM S PrpF protein
EHHHJOPM_00618 3.7e-162 yraN K Transcriptional regulator
EHHHJOPM_00619 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EHHHJOPM_00620 9.6e-183 scrR K transcriptional
EHHHJOPM_00621 2.3e-218 rafB P LacY proton/sugar symporter
EHHHJOPM_00622 1.6e-290 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
EHHHJOPM_00624 2.6e-33
EHHHJOPM_00625 7.3e-264 I Pfam Lipase (class 3)
EHHHJOPM_00626 9.8e-18 S Protein of unknown function (DUF1433)
EHHHJOPM_00627 2.2e-17 S Protein of unknown function (DUF1433)
EHHHJOPM_00628 2.3e-15 S Protein of unknown function (DUF1433)
EHHHJOPM_00629 1.5e-38 S Protein of unknown function (DUF1433)
EHHHJOPM_00630 1.6e-93 padC Q Phenolic acid decarboxylase
EHHHJOPM_00631 3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHHHJOPM_00632 3.4e-112 yyaS S Membrane
EHHHJOPM_00633 3.7e-96 ywjB H RibD C-terminal domain
EHHHJOPM_00635 3.8e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
EHHHJOPM_00636 1.9e-77 slr K transcriptional
EHHHJOPM_00637 1.6e-118 ywqC M biosynthesis protein
EHHHJOPM_00638 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
EHHHJOPM_00639 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
EHHHJOPM_00640 7.4e-219 epsD GT4 M Glycosyl transferase 4-like
EHHHJOPM_00641 2.6e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EHHHJOPM_00642 7.9e-213 epsF GT4 M Glycosyl transferases group 1
EHHHJOPM_00643 7.7e-205 epsG S EpsG family
EHHHJOPM_00644 1.9e-192 epsH GT2 S Glycosyltransferase like family 2
EHHHJOPM_00645 1.1e-203 epsI GM pyruvyl transferase
EHHHJOPM_00646 7.5e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
EHHHJOPM_00647 1.6e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHHJOPM_00648 6.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EHHHJOPM_00649 4.2e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
EHHHJOPM_00650 4.1e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EHHHJOPM_00651 1.9e-183 yvfF GM Exopolysaccharide biosynthesis protein
EHHHJOPM_00652 2.7e-32 yvfG S YvfG protein
EHHHJOPM_00653 1.4e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EHHHJOPM_00654 2.5e-303 yvfH C L-lactate permease
EHHHJOPM_00655 1.5e-119 yvfI K COG2186 Transcriptional regulators
EHHHJOPM_00656 1.3e-218 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHHHJOPM_00657 4.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EHHHJOPM_00658 2.8e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EHHHJOPM_00659 2.2e-131 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EHHHJOPM_00660 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
EHHHJOPM_00661 1.2e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
EHHHJOPM_00662 1.9e-150 ybbH_1 K RpiR family transcriptional regulator
EHHHJOPM_00663 7e-164 3.1.3.104 S hydrolases of the HAD superfamily
EHHHJOPM_00664 3.4e-115 yyaS S Membrane
EHHHJOPM_00665 2.1e-182 purR7 5.1.1.1 K Transcriptional regulator
EHHHJOPM_00666 4.2e-258
EHHHJOPM_00667 3.9e-198 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
EHHHJOPM_00668 7.7e-158 yvbV EG EamA-like transporter family
EHHHJOPM_00669 2.4e-156 yvbU K Transcriptional regulator
EHHHJOPM_00671 8.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHHJOPM_00672 1.4e-203 araR K transcriptional
EHHHJOPM_00673 7.4e-253 araE EGP Major facilitator Superfamily
EHHHJOPM_00675 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EHHHJOPM_00676 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EHHHJOPM_00677 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EHHHJOPM_00678 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EHHHJOPM_00679 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
EHHHJOPM_00680 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EHHHJOPM_00681 3.2e-234 ywaD 3.4.11.10, 3.4.11.6 S PA domain
EHHHJOPM_00682 8.9e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EHHHJOPM_00683 2.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
EHHHJOPM_00684 4e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
EHHHJOPM_00685 6.9e-226 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EHHHJOPM_00686 1e-146 M Protein involved in cellulose biosynthesis
EHHHJOPM_00687 2.1e-142 C WbqC-like protein family
EHHHJOPM_00688 4.1e-124 S GlcNAc-PI de-N-acetylase
EHHHJOPM_00689 3.3e-177
EHHHJOPM_00690 6.2e-211 EGP Major facilitator Superfamily
EHHHJOPM_00691 1.5e-80 yvbK 3.1.3.25 K acetyltransferase
EHHHJOPM_00692 0.0 tcaA S response to antibiotic
EHHHJOPM_00693 6.4e-120 exoY M Membrane
EHHHJOPM_00694 4.4e-93 yvbG U UPF0056 membrane protein
EHHHJOPM_00695 3.5e-97 yvbF K Belongs to the GbsR family
EHHHJOPM_00696 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EHHHJOPM_00697 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EHHHJOPM_00698 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EHHHJOPM_00699 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EHHHJOPM_00700 4.3e-76 yvbF K Belongs to the GbsR family
EHHHJOPM_00701 2.9e-207 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EHHHJOPM_00702 1.2e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
EHHHJOPM_00703 3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EHHHJOPM_00704 5.2e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
EHHHJOPM_00705 1.2e-126 mutF V ABC transporter, ATP-binding protein
EHHHJOPM_00706 4.9e-123 spaE S ABC-2 family transporter protein
EHHHJOPM_00707 5.9e-135 mutG S ABC-2 family transporter protein
EHHHJOPM_00708 1.4e-121 K Transcriptional regulatory protein, C terminal
EHHHJOPM_00709 1.8e-259 T His Kinase A (phosphoacceptor) domain
EHHHJOPM_00710 8.8e-53 yodB K transcriptional
EHHHJOPM_00711 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
EHHHJOPM_00712 1e-69 K transcriptional
EHHHJOPM_00713 6e-35 yvzC K Transcriptional
EHHHJOPM_00714 4.8e-24 secG U Preprotein translocase subunit SecG
EHHHJOPM_00715 1.6e-142 est 3.1.1.1 S Carboxylesterase
EHHHJOPM_00716 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EHHHJOPM_00717 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHHHJOPM_00719 7.9e-56
EHHHJOPM_00720 1.1e-47 yrdF K ribonuclease inhibitor
EHHHJOPM_00721 4.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHHJOPM_00722 7.2e-161 ytlI K LysR substrate binding domain
EHHHJOPM_00723 3e-101 ytmI K Acetyltransferase (GNAT) domain
EHHHJOPM_00724 3.9e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
EHHHJOPM_00725 5.4e-147 tcyK M Bacterial periplasmic substrate-binding proteins
EHHHJOPM_00726 1.7e-120 tcyL P Binding-protein-dependent transport system inner membrane component
EHHHJOPM_00727 1.1e-119 tcyM U Binding-protein-dependent transport system inner membrane component
EHHHJOPM_00728 1e-139 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EHHHJOPM_00729 9.3e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHHJOPM_00730 2.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
EHHHJOPM_00731 3.2e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHHJOPM_00732 1.1e-141 S Amidohydrolase
EHHHJOPM_00733 9.1e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
EHHHJOPM_00734 2.8e-216 ynfM EGP Major Facilitator Superfamily
EHHHJOPM_00735 8.4e-159 K Helix-turn-helix XRE-family like proteins
EHHHJOPM_00736 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHHHJOPM_00737 4.1e-192 yvaA 1.1.1.371 S Oxidoreductase
EHHHJOPM_00738 3.7e-48 csoR S transcriptional
EHHHJOPM_00739 2.6e-29 copZ P Heavy-metal-associated domain
EHHHJOPM_00740 0.0 copA 3.6.3.54 P P-type ATPase
EHHHJOPM_00741 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EHHHJOPM_00742 7.5e-102 bdbD O Thioredoxin
EHHHJOPM_00743 6e-73 bdbC O Required for disulfide bond formation in some proteins
EHHHJOPM_00744 3.7e-140 S Metallo-peptidase family M12
EHHHJOPM_00745 2.9e-97 yvgT S membrane
EHHHJOPM_00746 0.0 helD 3.6.4.12 L DNA helicase
EHHHJOPM_00747 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHHHJOPM_00748 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EHHHJOPM_00749 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
EHHHJOPM_00750 2.7e-85 yvgO
EHHHJOPM_00751 1.1e-155 yvgN S reductase
EHHHJOPM_00752 7e-193 yfiN V COG0842 ABC-type multidrug transport system, permease component
EHHHJOPM_00753 1.3e-191 yfiM V ABC-2 type transporter
EHHHJOPM_00754 2.1e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
EHHHJOPM_00755 6.2e-178 T Histidine kinase
EHHHJOPM_00756 8.6e-114 yfiK K Regulator
EHHHJOPM_00757 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
EHHHJOPM_00758 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
EHHHJOPM_00759 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
EHHHJOPM_00760 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EHHHJOPM_00761 5.1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
EHHHJOPM_00762 5.2e-13 S Small spore protein J (Spore_SspJ)
EHHHJOPM_00763 7e-235 yvsH E Arginine ornithine antiporter
EHHHJOPM_00764 3.1e-127 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EHHHJOPM_00765 4e-178 fhuD P ABC transporter
EHHHJOPM_00766 3.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHHJOPM_00767 7.6e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHHJOPM_00768 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
EHHHJOPM_00769 2.7e-65 yvrL S Regulatory protein YrvL
EHHHJOPM_00770 3.9e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
EHHHJOPM_00771 1.6e-15 S YvrJ protein family
EHHHJOPM_00772 3.8e-102 yvrI K RNA polymerase
EHHHJOPM_00773 7.3e-36
EHHHJOPM_00774 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHHJOPM_00775 0.0 T PhoQ Sensor
EHHHJOPM_00776 4.2e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
EHHHJOPM_00777 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHHJOPM_00778 2.7e-166 yvrC P ABC transporter substrate-binding protein
EHHHJOPM_00779 1.7e-177 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHHJOPM_00780 7.2e-220 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EHHHJOPM_00781 3.1e-101 yvqK 2.5.1.17 S Adenosyltransferase
EHHHJOPM_00782 1.8e-226 yvqJ EGP Major facilitator Superfamily
EHHHJOPM_00783 5.3e-44 liaI S membrane
EHHHJOPM_00784 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EHHHJOPM_00785 7.4e-126 liaG S Putative adhesin
EHHHJOPM_00786 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
EHHHJOPM_00787 2.3e-193 vraS 2.7.13.3 T Histidine kinase
EHHHJOPM_00788 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHHJOPM_00789 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
EHHHJOPM_00790 3.6e-186 gerAB E Spore germination protein
EHHHJOPM_00791 6e-258 gerAA EG Spore germination protein
EHHHJOPM_00792 6.6e-24 S Protein of unknown function (DUF3970)
EHHHJOPM_00793 8.7e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EHHHJOPM_00794 2.2e-157 yuxN K Transcriptional regulator
EHHHJOPM_00795 3.4e-24
EHHHJOPM_00796 2.2e-249 cssS 2.7.13.3 T PhoQ Sensor
EHHHJOPM_00797 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHHJOPM_00798 1.9e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHHHJOPM_00799 4.7e-79 dps P Belongs to the Dps family
EHHHJOPM_00800 1.1e-147 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHHJOPM_00801 0.0 pepF2 E COG1164 Oligoendopeptidase F
EHHHJOPM_00802 7.2e-45 S YusW-like protein
EHHHJOPM_00803 3.1e-150 yusV 3.6.3.34 HP ABC transporter
EHHHJOPM_00804 3.3e-39 yusU S Protein of unknown function (DUF2573)
EHHHJOPM_00805 2.4e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHHHJOPM_00806 4.2e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
EHHHJOPM_00807 1e-154 ywbI2 K Transcriptional regulator
EHHHJOPM_00808 4e-287 yusP P Major facilitator superfamily
EHHHJOPM_00809 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
EHHHJOPM_00810 1.1e-53 yusN M Coat F domain
EHHHJOPM_00811 5.7e-42
EHHHJOPM_00812 3.2e-164 fadM E Proline dehydrogenase
EHHHJOPM_00813 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
EHHHJOPM_00814 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
EHHHJOPM_00815 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
EHHHJOPM_00816 6.2e-63 arsC 1.20.4.1 P Belongs to the ArsC family
EHHHJOPM_00817 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EHHHJOPM_00818 3.7e-40 yusG S Protein of unknown function (DUF2553)
EHHHJOPM_00819 1.4e-62 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
EHHHJOPM_00820 1.6e-54 yusE CO Thioredoxin
EHHHJOPM_00821 1.5e-56 yusD S SCP-2 sterol transfer family
EHHHJOPM_00822 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHHHJOPM_00823 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
EHHHJOPM_00824 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
EHHHJOPM_00825 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHHHJOPM_00826 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EHHHJOPM_00827 1.2e-244 sufD O assembly protein SufD
EHHHJOPM_00828 1.4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHHHJOPM_00829 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
EHHHJOPM_00830 8.7e-270 sufB O FeS cluster assembly
EHHHJOPM_00831 1e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EHHHJOPM_00832 2.2e-24 yncE S Protein of unknown function (DUF2691)
EHHHJOPM_00833 3.1e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
EHHHJOPM_00834 7e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
EHHHJOPM_00836 5e-165 K helix_turn_helix, mercury resistance
EHHHJOPM_00837 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EHHHJOPM_00838 1.4e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
EHHHJOPM_00839 9.8e-158 yurN G Binding-protein-dependent transport system inner membrane component
EHHHJOPM_00840 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
EHHHJOPM_00841 1.5e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
EHHHJOPM_00842 3.6e-134 yurK K UTRA
EHHHJOPM_00843 2.7e-205 msmX P Belongs to the ABC transporter superfamily
EHHHJOPM_00844 1.6e-165 bsn L Ribonuclease
EHHHJOPM_00845 5.2e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EHHHJOPM_00846 5.6e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EHHHJOPM_00847 4.1e-212 blt EGP Major facilitator Superfamily
EHHHJOPM_00848 1.6e-73
EHHHJOPM_00849 1.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
EHHHJOPM_00850 1.5e-261 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EHHHJOPM_00851 2.4e-59 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
EHHHJOPM_00852 1.5e-168 yunF S Protein of unknown function DUF72
EHHHJOPM_00853 1.1e-144 yunE S membrane transporter protein
EHHHJOPM_00854 3.5e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EHHHJOPM_00855 2.5e-130 yunB S Sporulation protein YunB (Spo_YunB)
EHHHJOPM_00856 1.5e-191 lytH M Peptidase, M23
EHHHJOPM_00857 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EHHHJOPM_00858 1.7e-47 yutD S protein conserved in bacteria
EHHHJOPM_00859 6.8e-72 yutE S Protein of unknown function DUF86
EHHHJOPM_00860 1.4e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EHHHJOPM_00861 3.3e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
EHHHJOPM_00862 3e-195 yutH S Spore coat protein
EHHHJOPM_00863 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
EHHHJOPM_00864 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EHHHJOPM_00865 9.8e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EHHHJOPM_00866 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
EHHHJOPM_00867 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
EHHHJOPM_00868 1.1e-53 yuzD S protein conserved in bacteria
EHHHJOPM_00869 2.7e-207 yutJ 1.6.99.3 C NADH dehydrogenase
EHHHJOPM_00870 9.2e-39 yuzB S Belongs to the UPF0349 family
EHHHJOPM_00871 3.2e-212 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHHHJOPM_00872 1.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHHHJOPM_00873 1.1e-62 erpA S Belongs to the HesB IscA family
EHHHJOPM_00874 1.6e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHHJOPM_00875 2.3e-26 K helix_turn_helix, mercury resistance
EHHHJOPM_00877 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
EHHHJOPM_00879 1.5e-121 V ABC transporter
EHHHJOPM_00880 1e-69 CP Membrane
EHHHJOPM_00881 4.8e-29
EHHHJOPM_00882 1.1e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EHHHJOPM_00884 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
EHHHJOPM_00885 9.4e-236 yumB 1.6.99.3 C NADH dehydrogenase
EHHHJOPM_00886 9.9e-28 yuiB S Putative membrane protein
EHHHJOPM_00887 1.3e-116 yuiC S protein conserved in bacteria
EHHHJOPM_00888 1.6e-77 yuiD S protein conserved in bacteria
EHHHJOPM_00889 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHHHJOPM_00890 1.2e-207 yuiF S antiporter
EHHHJOPM_00891 1.5e-101 bioY S Biotin biosynthesis protein
EHHHJOPM_00892 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
EHHHJOPM_00893 4.4e-163 besA S Putative esterase
EHHHJOPM_00894 2.4e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHHJOPM_00895 8.6e-218 entC 5.4.4.2 HQ Isochorismate synthase
EHHHJOPM_00896 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
EHHHJOPM_00897 3.6e-171 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
EHHHJOPM_00898 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_00899 1.1e-33 mbtH S MbtH-like protein
EHHHJOPM_00900 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
EHHHJOPM_00901 3.9e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
EHHHJOPM_00902 4.2e-228 yukF QT Transcriptional regulator
EHHHJOPM_00903 3.3e-46 esxA S Belongs to the WXG100 family
EHHHJOPM_00904 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
EHHHJOPM_00905 1.4e-202 essB S WXG100 protein secretion system (Wss), protein YukC
EHHHJOPM_00906 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EHHHJOPM_00907 0.0 esaA S type VII secretion protein EsaA
EHHHJOPM_00908 8.5e-76 yueC S Family of unknown function (DUF5383)
EHHHJOPM_00909 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHHJOPM_00910 8.3e-96 yueE S phosphohydrolase
EHHHJOPM_00911 1.6e-22 S Protein of unknown function (DUF2642)
EHHHJOPM_00912 3.6e-186 yueF S transporter activity
EHHHJOPM_00913 6.4e-34 yueG S Spore germination protein gerPA/gerPF
EHHHJOPM_00914 2.8e-38 yueH S YueH-like protein
EHHHJOPM_00915 7.2e-68 yueI S Protein of unknown function (DUF1694)
EHHHJOPM_00916 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
EHHHJOPM_00917 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHHHJOPM_00918 8.5e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
EHHHJOPM_00919 1.2e-50 yuzC
EHHHJOPM_00922 8.9e-98 comQ H Belongs to the FPP GGPP synthase family
EHHHJOPM_00924 6e-276 comP 2.7.13.3 T Histidine kinase
EHHHJOPM_00925 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHHJOPM_00926 1.1e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
EHHHJOPM_00927 1.1e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
EHHHJOPM_00928 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHHHJOPM_00929 8.5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHHHJOPM_00930 1.7e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHHHJOPM_00931 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHHHJOPM_00932 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EHHHJOPM_00933 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EHHHJOPM_00934 2.3e-12
EHHHJOPM_00935 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
EHHHJOPM_00936 8.4e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
EHHHJOPM_00937 2.8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EHHHJOPM_00938 1.7e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EHHHJOPM_00939 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
EHHHJOPM_00940 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EHHHJOPM_00941 9.3e-74 yufK S Family of unknown function (DUF5366)
EHHHJOPM_00942 2.2e-72 yuxK S protein conserved in bacteria
EHHHJOPM_00943 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
EHHHJOPM_00944 1.5e-185 yuxJ EGP Major facilitator Superfamily
EHHHJOPM_00945 3.1e-118 kapD L the KinA pathway to sporulation
EHHHJOPM_00946 7.7e-67 kapB G Kinase associated protein B
EHHHJOPM_00947 3.1e-229 T PhoQ Sensor
EHHHJOPM_00948 3.3e-222 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EHHHJOPM_00949 1.4e-40 yugE S Domain of unknown function (DUF1871)
EHHHJOPM_00950 5.5e-155 yugF I Hydrolase
EHHHJOPM_00951 2e-83 alaR K Transcriptional regulator
EHHHJOPM_00952 1.6e-208 yugH 2.6.1.1 E Aminotransferase
EHHHJOPM_00953 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
EHHHJOPM_00954 1.8e-34 yuzA S Domain of unknown function (DUF378)
EHHHJOPM_00955 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
EHHHJOPM_00956 1.8e-228 yugK C Dehydrogenase
EHHHJOPM_00957 5.5e-118 ycaC Q Isochorismatase family
EHHHJOPM_00958 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
EHHHJOPM_00960 7e-71 yugN S YugN-like family
EHHHJOPM_00961 5.3e-181 yugO P COG1226 Kef-type K transport systems
EHHHJOPM_00962 2.5e-26 mstX S Membrane-integrating protein Mistic
EHHHJOPM_00963 3.4e-18
EHHHJOPM_00964 3.2e-116 yugP S Zn-dependent protease
EHHHJOPM_00965 2.5e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
EHHHJOPM_00966 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
EHHHJOPM_00967 1e-72 yugU S Uncharacterised protein family UPF0047
EHHHJOPM_00968 8e-188 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EHHHJOPM_00969 1.4e-40
EHHHJOPM_00970 2.2e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
EHHHJOPM_00971 8.1e-221 mcpA NT chemotaxis protein
EHHHJOPM_00972 1.5e-235 mcpA NT chemotaxis protein
EHHHJOPM_00973 6e-224 mcpA NT chemotaxis protein
EHHHJOPM_00974 2.6e-235 mcpA NT chemotaxis protein
EHHHJOPM_00975 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
EHHHJOPM_00976 6.1e-185 ygjR S Oxidoreductase
EHHHJOPM_00977 6.5e-194 yubA S transporter activity
EHHHJOPM_00978 6.8e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EHHHJOPM_00980 5e-17
EHHHJOPM_00981 1.5e-13
EHHHJOPM_00982 1.7e-130 S Aspartate phosphatase response regulator
EHHHJOPM_00985 1.3e-51 yjcN
EHHHJOPM_00986 1.4e-118 G Cupin
EHHHJOPM_00987 2.5e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHHHJOPM_00988 1.5e-144 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EHHHJOPM_00989 2.7e-119 ktrA P COG0569 K transport systems, NAD-binding component
EHHHJOPM_00990 7.9e-94 yuaB
EHHHJOPM_00991 8.6e-96 yuaC K Belongs to the GbsR family
EHHHJOPM_00992 3.2e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
EHHHJOPM_00993 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
EHHHJOPM_00994 7.1e-109 yuaD S MOSC domain
EHHHJOPM_00995 6.9e-73 yuaE S DinB superfamily
EHHHJOPM_00996 7.3e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
EHHHJOPM_00997 3.2e-177 yuaG 3.4.21.72 S protein conserved in bacteria
EHHHJOPM_00998 1.1e-96 thiT S Thiamine transporter protein (Thia_YuaJ)
EHHHJOPM_00999 3.4e-39 S COG NOG14552 non supervised orthologous group
EHHHJOPM_01004 1.6e-08
EHHHJOPM_01011 1.3e-09
EHHHJOPM_01012 7.8e-08
EHHHJOPM_01021 2.6e-77 tspO T membrane
EHHHJOPM_01022 2.4e-130 dksA T COG1734 DnaK suppressor protein
EHHHJOPM_01023 5.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
EHHHJOPM_01024 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHHHJOPM_01025 3.9e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EHHHJOPM_01026 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHHHJOPM_01027 4.1e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EHHHJOPM_01028 1.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EHHHJOPM_01029 2e-23 S Domain of Unknown Function (DUF1540)
EHHHJOPM_01030 1.6e-183 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EHHHJOPM_01031 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
EHHHJOPM_01032 7.9e-41 rpmE2 J Ribosomal protein L31
EHHHJOPM_01033 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
EHHHJOPM_01034 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EHHHJOPM_01035 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EHHHJOPM_01036 5.7e-74 ytkA S YtkA-like
EHHHJOPM_01038 7.8e-76 dps P Belongs to the Dps family
EHHHJOPM_01039 5e-61 ytkC S Bacteriophage holin family
EHHHJOPM_01040 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
EHHHJOPM_01041 6.9e-126 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EHHHJOPM_01042 3.2e-144 ytlC P ABC transporter
EHHHJOPM_01043 2.6e-183 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EHHHJOPM_01044 1.5e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EHHHJOPM_01045 1.6e-38 ytmB S Protein of unknown function (DUF2584)
EHHHJOPM_01046 4.5e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EHHHJOPM_01047 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHHHJOPM_01048 0.0 asnB 6.3.5.4 E Asparagine synthase
EHHHJOPM_01049 1.1e-259 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
EHHHJOPM_01050 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EHHHJOPM_01051 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
EHHHJOPM_01052 7.1e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
EHHHJOPM_01053 1.5e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
EHHHJOPM_01055 7.4e-106 ytqB J Putative rRNA methylase
EHHHJOPM_01056 1.1e-189 yhcC S Fe-S oxidoreductase
EHHHJOPM_01057 1.3e-39 ytzC S Protein of unknown function (DUF2524)
EHHHJOPM_01059 3.9e-66 ytrA K GntR family transcriptional regulator
EHHHJOPM_01060 1.9e-161 ytrB P abc transporter atp-binding protein
EHHHJOPM_01061 1.3e-163 S ABC-2 family transporter protein
EHHHJOPM_01062 3.5e-172 P ABC-2 family transporter protein
EHHHJOPM_01063 1.4e-152
EHHHJOPM_01064 2.2e-125 ytrE V ABC transporter, ATP-binding protein
EHHHJOPM_01065 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
EHHHJOPM_01066 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHHJOPM_01067 8.7e-179 T PhoQ Sensor
EHHHJOPM_01068 4.9e-134 bceA V ABC transporter, ATP-binding protein
EHHHJOPM_01069 0.0 bceB V ABC transporter (permease)
EHHHJOPM_01070 1.4e-122 ywaF S Integral membrane protein
EHHHJOPM_01071 2.3e-207 yttB EGP Major facilitator Superfamily
EHHHJOPM_01072 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EHHHJOPM_01073 1.2e-52 ytvB S Protein of unknown function (DUF4257)
EHHHJOPM_01074 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EHHHJOPM_01075 5.6e-52 ytwF P Sulfurtransferase
EHHHJOPM_01076 1.7e-84 M Acetyltransferase (GNAT) domain
EHHHJOPM_01077 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
EHHHJOPM_01078 1.8e-142 amyC P ABC transporter (permease)
EHHHJOPM_01079 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
EHHHJOPM_01080 4.9e-243 msmE G Bacterial extracellular solute-binding protein
EHHHJOPM_01081 4.8e-185 msmR K Transcriptional regulator
EHHHJOPM_01082 9e-26 yteV S Sporulation protein Cse60
EHHHJOPM_01083 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
EHHHJOPM_01084 5.7e-236 ytfP S HI0933-like protein
EHHHJOPM_01085 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHHJOPM_01086 2.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EHHHJOPM_01087 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
EHHHJOPM_01088 3.7e-128 ythP V ABC transporter
EHHHJOPM_01089 4.6e-216 ythQ U Bacterial ABC transporter protein EcsB
EHHHJOPM_01090 1.3e-227 pbuO S permease
EHHHJOPM_01091 3.1e-267 pepV 3.5.1.18 E Dipeptidase
EHHHJOPM_01092 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EHHHJOPM_01093 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EHHHJOPM_01094 1.3e-165 ytlQ
EHHHJOPM_01095 1.5e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
EHHHJOPM_01096 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
EHHHJOPM_01097 3.5e-45 ytzH S YtzH-like protein
EHHHJOPM_01098 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EHHHJOPM_01099 6.2e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
EHHHJOPM_01100 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
EHHHJOPM_01101 1.7e-51 ytzB S small secreted protein
EHHHJOPM_01102 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EHHHJOPM_01103 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
EHHHJOPM_01104 7.9e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EHHHJOPM_01105 3.7e-148 ytpQ S Belongs to the UPF0354 family
EHHHJOPM_01106 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EHHHJOPM_01107 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
EHHHJOPM_01108 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EHHHJOPM_01109 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EHHHJOPM_01110 1.7e-16 ytxH S COG4980 Gas vesicle protein
EHHHJOPM_01111 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
EHHHJOPM_01112 1.2e-194 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EHHHJOPM_01113 6.4e-182 ccpA K catabolite control protein A
EHHHJOPM_01114 6.6e-145 motA N flagellar motor
EHHHJOPM_01115 4.8e-120 motS N Flagellar motor protein
EHHHJOPM_01116 9e-228 acuC BQ histone deacetylase
EHHHJOPM_01117 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
EHHHJOPM_01118 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EHHHJOPM_01119 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EHHHJOPM_01120 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHHHJOPM_01121 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
EHHHJOPM_01122 2e-124 azlC E AzlC protein
EHHHJOPM_01123 2.8e-148 K Transcriptional regulator
EHHHJOPM_01124 8.1e-149 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHHHJOPM_01125 1.5e-135 E GDSL-like Lipase/Acylhydrolase family
EHHHJOPM_01127 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
EHHHJOPM_01128 2.5e-09
EHHHJOPM_01129 9.2e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHHHJOPM_01130 1.7e-99 yokH G SMI1 / KNR4 family
EHHHJOPM_01131 5.5e-253 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
EHHHJOPM_01132 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EHHHJOPM_01133 2.3e-283 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
EHHHJOPM_01134 1.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
EHHHJOPM_01135 3.8e-108 yttP K Transcriptional regulator
EHHHJOPM_01136 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EHHHJOPM_01137 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EHHHJOPM_01138 2.2e-238 braB E Component of the transport system for branched-chain amino acids
EHHHJOPM_01139 6.6e-207 iscS2 2.8.1.7 E Cysteine desulfurase
EHHHJOPM_01140 5.6e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHHHJOPM_01141 3.9e-31 sspB S spore protein
EHHHJOPM_01142 4.2e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EHHHJOPM_01143 0.0 ytcJ S amidohydrolase
EHHHJOPM_01144 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHHHJOPM_01145 6.4e-182 sppA OU signal peptide peptidase SppA
EHHHJOPM_01146 4.5e-88 yteJ S RDD family
EHHHJOPM_01147 1e-93 ytfI S Protein of unknown function (DUF2953)
EHHHJOPM_01148 1.6e-60 ytfJ S Sporulation protein YtfJ
EHHHJOPM_01149 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EHHHJOPM_01150 2e-180 ytxK 2.1.1.72 L DNA methylase
EHHHJOPM_01151 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHHHJOPM_01152 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
EHHHJOPM_01153 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EHHHJOPM_01154 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
EHHHJOPM_01156 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHHJOPM_01157 1.3e-128 ytkL S Belongs to the UPF0173 family
EHHHJOPM_01158 1.6e-236 ytoI K transcriptional regulator containing CBS domains
EHHHJOPM_01159 1.5e-46 ytpI S YtpI-like protein
EHHHJOPM_01160 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
EHHHJOPM_01161 5.8e-23
EHHHJOPM_01162 4.3e-86 ytrI
EHHHJOPM_01163 3.2e-56 ytrH S Sporulation protein YtrH
EHHHJOPM_01164 0.0 dnaE 2.7.7.7 L DNA polymerase
EHHHJOPM_01165 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
EHHHJOPM_01166 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHHHJOPM_01167 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EHHHJOPM_01168 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EHHHJOPM_01169 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EHHHJOPM_01170 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
EHHHJOPM_01171 6.9e-193 ytvI S sporulation integral membrane protein YtvI
EHHHJOPM_01172 1.1e-72 yeaL S membrane
EHHHJOPM_01173 2.1e-46 yjdF S Protein of unknown function (DUF2992)
EHHHJOPM_01174 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
EHHHJOPM_01175 2.7e-241 icd 1.1.1.42 C isocitrate
EHHHJOPM_01176 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
EHHHJOPM_01177 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHHJOPM_01178 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
EHHHJOPM_01179 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHHHJOPM_01180 9.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EHHHJOPM_01181 6.2e-106 ytaF P Probably functions as a manganese efflux pump
EHHHJOPM_01182 2e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EHHHJOPM_01183 1.7e-159 ytbE S reductase
EHHHJOPM_01184 4.5e-206 ytbD EGP Major facilitator Superfamily
EHHHJOPM_01185 2e-67 ytcD K Transcriptional regulator
EHHHJOPM_01186 2.2e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EHHHJOPM_01187 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EHHHJOPM_01188 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHHHJOPM_01189 3.1e-251 dnaB L Membrane attachment protein
EHHHJOPM_01190 9.5e-172 dnaI L Primosomal protein DnaI
EHHHJOPM_01191 2.1e-106 ytxB S SNARE associated Golgi protein
EHHHJOPM_01192 6.7e-153 ytxC S YtxC-like family
EHHHJOPM_01193 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHHHJOPM_01194 8.7e-150 ysaA S HAD-hyrolase-like
EHHHJOPM_01195 0.0 lytS 2.7.13.3 T Histidine kinase
EHHHJOPM_01196 2.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
EHHHJOPM_01197 2.9e-38 lrgA S effector of murein hydrolase LrgA
EHHHJOPM_01198 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EHHHJOPM_01199 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EHHHJOPM_01200 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EHHHJOPM_01201 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EHHHJOPM_01202 6.1e-34 ysdA S Membrane
EHHHJOPM_01203 1.9e-65 ysdB S Sigma-w pathway protein YsdB
EHHHJOPM_01204 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
EHHHJOPM_01205 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
EHHHJOPM_01206 4.4e-296 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EHHHJOPM_01207 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
EHHHJOPM_01208 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EHHHJOPM_01209 7.8e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EHHHJOPM_01210 4.4e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EHHHJOPM_01211 2.9e-251 araN G carbohydrate transport
EHHHJOPM_01212 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
EHHHJOPM_01213 1.2e-144 araQ G transport system permease
EHHHJOPM_01214 8.6e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
EHHHJOPM_01215 0.0 cstA T Carbon starvation protein
EHHHJOPM_01216 8.9e-256 glcF C Glycolate oxidase
EHHHJOPM_01217 1.6e-258 glcD 1.1.3.15 C FAD binding domain
EHHHJOPM_01218 2.7e-202 ysfB KT regulator
EHHHJOPM_01219 2e-32 sspI S Belongs to the SspI family
EHHHJOPM_01220 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHHHJOPM_01221 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHHHJOPM_01222 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EHHHJOPM_01223 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHHHJOPM_01224 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHHHJOPM_01225 3.6e-83 cvpA S membrane protein, required for colicin V production
EHHHJOPM_01226 0.0 polX L COG1796 DNA polymerase IV (family X)
EHHHJOPM_01227 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EHHHJOPM_01228 4.7e-67 yshE S membrane
EHHHJOPM_01229 1.6e-115 ywbB S Protein of unknown function (DUF2711)
EHHHJOPM_01230 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHHHJOPM_01231 2.7e-103 fadR K Transcriptional regulator
EHHHJOPM_01232 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EHHHJOPM_01233 1.7e-137 etfB C Electron transfer flavoprotein
EHHHJOPM_01234 1.6e-177 etfA C Electron transfer flavoprotein
EHHHJOPM_01235 4.3e-299 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
EHHHJOPM_01236 2.5e-52 trxA O Belongs to the thioredoxin family
EHHHJOPM_01237 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EHHHJOPM_01238 1.6e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EHHHJOPM_01239 2e-79 yslB S Protein of unknown function (DUF2507)
EHHHJOPM_01240 4.8e-108 sdhC C succinate dehydrogenase
EHHHJOPM_01241 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EHHHJOPM_01242 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
EHHHJOPM_01243 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
EHHHJOPM_01244 2e-30 gerE K Transcriptional regulator
EHHHJOPM_01245 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
EHHHJOPM_01246 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EHHHJOPM_01247 5.8e-197 gerM S COG5401 Spore germination protein
EHHHJOPM_01248 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHHHJOPM_01249 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHHHJOPM_01250 5.9e-91 ysnB S Phosphoesterase
EHHHJOPM_01255 0.0 ilvB 2.2.1.6 E Acetolactate synthase
EHHHJOPM_01256 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
EHHHJOPM_01257 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHHHJOPM_01258 7.9e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHHHJOPM_01259 2.4e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EHHHJOPM_01260 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHHHJOPM_01261 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHHHJOPM_01262 1.6e-188 ysoA H Tetratricopeptide repeat
EHHHJOPM_01263 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EHHHJOPM_01264 8.5e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHHHJOPM_01265 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
EHHHJOPM_01266 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHHHJOPM_01267 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
EHHHJOPM_01268 3.8e-87 ysxD
EHHHJOPM_01269 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHHHJOPM_01270 1e-145 hemX O cytochrome C
EHHHJOPM_01271 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EHHHJOPM_01272 1.6e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EHHHJOPM_01273 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
EHHHJOPM_01274 2e-244 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EHHHJOPM_01275 1.6e-218 spoVID M stage VI sporulation protein D
EHHHJOPM_01276 3.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHHHJOPM_01277 2.1e-25
EHHHJOPM_01278 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EHHHJOPM_01279 4.8e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EHHHJOPM_01280 1.1e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EHHHJOPM_01281 2.8e-137 spoIIB S Sporulation related domain
EHHHJOPM_01282 2.1e-97 maf D septum formation protein Maf
EHHHJOPM_01283 1.8e-127 radC E Belongs to the UPF0758 family
EHHHJOPM_01284 4e-184 mreB D Rod shape-determining protein MreB
EHHHJOPM_01285 3.6e-157 mreC M Involved in formation and maintenance of cell shape
EHHHJOPM_01286 5.4e-84 mreD M shape-determining protein
EHHHJOPM_01287 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EHHHJOPM_01288 2.3e-142 minD D Belongs to the ParA family
EHHHJOPM_01289 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
EHHHJOPM_01290 4.6e-160 spoIVFB S Stage IV sporulation protein
EHHHJOPM_01291 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
EHHHJOPM_01292 7e-56 ysxB J ribosomal protein
EHHHJOPM_01293 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EHHHJOPM_01294 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
EHHHJOPM_01295 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHHHJOPM_01296 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
EHHHJOPM_01297 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
EHHHJOPM_01298 1.3e-93 niaR S small molecule binding protein (contains 3H domain)
EHHHJOPM_01299 2.1e-221 nifS 2.8.1.7 E Cysteine desulfurase
EHHHJOPM_01300 5.7e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
EHHHJOPM_01301 7.6e-152 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
EHHHJOPM_01302 2.2e-212 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHHHJOPM_01303 2.1e-115 safA M spore coat assembly protein SafA
EHHHJOPM_01304 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHHHJOPM_01306 3.7e-93 bofC S BofC C-terminal domain
EHHHJOPM_01307 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EHHHJOPM_01308 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EHHHJOPM_01309 2.8e-20 yrzS S Protein of unknown function (DUF2905)
EHHHJOPM_01310 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHHHJOPM_01311 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EHHHJOPM_01312 2.5e-37 yajC U Preprotein translocase subunit YajC
EHHHJOPM_01313 2.4e-60 yrzE S Protein of unknown function (DUF3792)
EHHHJOPM_01314 9.5e-110 yrbG S membrane
EHHHJOPM_01315 4.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHHJOPM_01316 8.5e-50 yrzD S Post-transcriptional regulator
EHHHJOPM_01317 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHHHJOPM_01318 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
EHHHJOPM_01319 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
EHHHJOPM_01320 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
EHHHJOPM_01321 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHHHJOPM_01322 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHHHJOPM_01323 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EHHHJOPM_01324 8.5e-274 lytH 3.5.1.28 M COG3103 SH3 domain protein
EHHHJOPM_01327 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
EHHHJOPM_01328 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHHHJOPM_01329 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EHHHJOPM_01330 2.4e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EHHHJOPM_01331 7.8e-64 cymR K Transcriptional regulator
EHHHJOPM_01332 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
EHHHJOPM_01333 2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EHHHJOPM_01334 1.7e-18 S COG0457 FOG TPR repeat
EHHHJOPM_01335 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EHHHJOPM_01336 3.4e-82 yrrD S protein conserved in bacteria
EHHHJOPM_01337 2.9e-30 yrzR
EHHHJOPM_01338 2.1e-08 S Protein of unknown function (DUF3918)
EHHHJOPM_01339 1.4e-105 glnP P ABC transporter
EHHHJOPM_01340 6.1e-109 gluC P ABC transporter
EHHHJOPM_01341 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
EHHHJOPM_01342 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EHHHJOPM_01343 4.3e-160 yrrI S AI-2E family transporter
EHHHJOPM_01344 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHHHJOPM_01345 8.5e-41 yrzL S Belongs to the UPF0297 family
EHHHJOPM_01346 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHHHJOPM_01347 7.1e-46 yrzB S Belongs to the UPF0473 family
EHHHJOPM_01348 4.1e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHHHJOPM_01349 2.3e-116 yrrM 2.1.1.104 S O-methyltransferase
EHHHJOPM_01350 2.9e-173 yegQ O Peptidase U32
EHHHJOPM_01351 6.1e-246 yegQ O COG0826 Collagenase and related proteases
EHHHJOPM_01352 3.4e-112 udk 2.7.1.48 F Cytidine monophosphokinase
EHHHJOPM_01353 2.7e-67 L Arm DNA-binding domain
EHHHJOPM_01354 5.5e-44
EHHHJOPM_01356 2.5e-25 K Helix-turn-helix XRE-family like proteins
EHHHJOPM_01359 5.7e-70 L dnaD_dom DnaD domain protein
EHHHJOPM_01360 4.8e-42 dnaC L IstB-like ATP binding protein
EHHHJOPM_01362 3.7e-07
EHHHJOPM_01363 5.8e-28
EHHHJOPM_01366 6.1e-15 yqaO S Phage-like element PBSX protein XtrA
EHHHJOPM_01369 1.2e-27
EHHHJOPM_01371 1.2e-167 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EHHHJOPM_01372 2e-125 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
EHHHJOPM_01375 2.4e-43 S dUTPase
EHHHJOPM_01378 1.5e-47
EHHHJOPM_01379 3e-42 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EHHHJOPM_01380 9.6e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
EHHHJOPM_01381 8.8e-77 L Phage integrase family
EHHHJOPM_01384 5.9e-25
EHHHJOPM_01386 5.2e-79 L phage terminase small subunit
EHHHJOPM_01387 2.2e-299 S Terminase
EHHHJOPM_01388 1.2e-169 S Phage portal protein
EHHHJOPM_01389 6.6e-84 S peptidase activity
EHHHJOPM_01390 1.2e-153 gp36 S capsid protein
EHHHJOPM_01391 3.1e-23
EHHHJOPM_01392 1.1e-39 S Phage gp6-like head-tail connector protein
EHHHJOPM_01393 5e-40 S Phage head-tail joining protein
EHHHJOPM_01394 1.3e-48 S Bacteriophage HK97-gp10, putative tail-component
EHHHJOPM_01396 1.2e-77 S Phage tail tube protein
EHHHJOPM_01398 0.0 D phage tail tape measure protein
EHHHJOPM_01399 4.5e-104 S Phage tail protein
EHHHJOPM_01400 8.2e-230 NU Prophage endopeptidase tail
EHHHJOPM_01401 0.0 M Pectate lyase superfamily protein
EHHHJOPM_01402 3.5e-148 S Domain of unknown function (DUF2479)
EHHHJOPM_01405 6e-65 S Pfam:Phage_holin_4_1
EHHHJOPM_01406 1e-70 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EHHHJOPM_01407 4.5e-07
EHHHJOPM_01410 1.1e-07
EHHHJOPM_01411 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EHHHJOPM_01412 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
EHHHJOPM_01413 8.1e-70 yrrS S Protein of unknown function (DUF1510)
EHHHJOPM_01414 1.6e-26 yrzA S Protein of unknown function (DUF2536)
EHHHJOPM_01415 2.1e-117 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
EHHHJOPM_01416 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHHHJOPM_01417 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
EHHHJOPM_01418 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EHHHJOPM_01419 5.1e-34 yrhC S YrhC-like protein
EHHHJOPM_01420 4.5e-80 yrhD S Protein of unknown function (DUF1641)
EHHHJOPM_01421 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
EHHHJOPM_01422 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
EHHHJOPM_01423 8e-143 focA P Formate nitrite
EHHHJOPM_01425 7.1e-79 yrhH Q methyltransferase
EHHHJOPM_01426 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
EHHHJOPM_01427 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EHHHJOPM_01428 5.5e-212 ynfM EGP Major facilitator Superfamily
EHHHJOPM_01429 4.1e-164 yybE K Transcriptional regulator
EHHHJOPM_01430 1.1e-78 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHHHJOPM_01431 2.1e-179 romA S Beta-lactamase superfamily domain
EHHHJOPM_01432 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
EHHHJOPM_01433 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
EHHHJOPM_01434 1.7e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
EHHHJOPM_01435 5.9e-129 glvR K Helix-turn-helix domain, rpiR family
EHHHJOPM_01436 1.6e-143 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
EHHHJOPM_01437 4.2e-144 S hydrolase
EHHHJOPM_01439 1.5e-91 yrdA S DinB family
EHHHJOPM_01440 4.3e-81 yyaR K Acetyltransferase (GNAT) domain
EHHHJOPM_01441 1.4e-219 tetL EGP Major facilitator Superfamily
EHHHJOPM_01443 4.9e-96 adk 2.7.4.3 F adenylate kinase activity
EHHHJOPM_01444 1e-146 ydeE K AraC family transcriptional regulator
EHHHJOPM_01445 3.6e-91 K Transcriptional regulator PadR-like family
EHHHJOPM_01446 6e-157 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
EHHHJOPM_01447 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHHJOPM_01448 1.1e-199 EGP Major facilitator Superfamily
EHHHJOPM_01449 8e-106 yqeD S SNARE associated Golgi protein
EHHHJOPM_01450 2.9e-139 3.5.1.104 G Polysaccharide deacetylase
EHHHJOPM_01451 2.5e-138 yqeF E GDSL-like Lipase/Acylhydrolase
EHHHJOPM_01453 7.6e-94 yqeG S hydrolase of the HAD superfamily
EHHHJOPM_01454 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EHHHJOPM_01455 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHHHJOPM_01456 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
EHHHJOPM_01457 2.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHHHJOPM_01458 1.6e-100 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EHHHJOPM_01459 2.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EHHHJOPM_01460 1.1e-138 yqeM Q Methyltransferase
EHHHJOPM_01461 6.5e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHHHJOPM_01462 9.6e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EHHHJOPM_01463 8e-105 comEB 3.5.4.12 F ComE operon protein 2
EHHHJOPM_01464 0.0 comEC S Competence protein ComEC
EHHHJOPM_01465 1.1e-11 comEC S Competence protein ComEC
EHHHJOPM_01466 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
EHHHJOPM_01467 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
EHHHJOPM_01468 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EHHHJOPM_01469 7.8e-219 spoIIP M stage II sporulation protein P
EHHHJOPM_01470 2.5e-53 yqxA S Protein of unknown function (DUF3679)
EHHHJOPM_01471 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EHHHJOPM_01472 2.2e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
EHHHJOPM_01473 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EHHHJOPM_01474 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHHHJOPM_01475 0.0 dnaK O Heat shock 70 kDa protein
EHHHJOPM_01476 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EHHHJOPM_01477 6.6e-173 prmA J Methylates ribosomal protein L11
EHHHJOPM_01478 5.1e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EHHHJOPM_01479 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
EHHHJOPM_01480 4.8e-155 yqeW P COG1283 Na phosphate symporter
EHHHJOPM_01481 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EHHHJOPM_01482 8e-68 yqeY S Yqey-like protein
EHHHJOPM_01483 3.1e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
EHHHJOPM_01484 3.8e-118 yqfA S UPF0365 protein
EHHHJOPM_01485 1.9e-42 yqfB
EHHHJOPM_01486 9.3e-46 yqfC S sporulation protein YqfC
EHHHJOPM_01487 1.7e-213 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
EHHHJOPM_01488 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
EHHHJOPM_01489 0.0 yqfF S membrane-associated HD superfamily hydrolase
EHHHJOPM_01490 9.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHHHJOPM_01491 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EHHHJOPM_01492 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EHHHJOPM_01493 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHHHJOPM_01494 1.8e-16 S YqzL-like protein
EHHHJOPM_01495 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
EHHHJOPM_01496 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EHHHJOPM_01497 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EHHHJOPM_01498 4.5e-112 ccpN K CBS domain
EHHHJOPM_01499 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EHHHJOPM_01500 1.3e-87 yaiI S Belongs to the UPF0178 family
EHHHJOPM_01501 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EHHHJOPM_01502 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EHHHJOPM_01503 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
EHHHJOPM_01504 2.9e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
EHHHJOPM_01505 1.1e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHHHJOPM_01506 6.5e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHHHJOPM_01507 3.7e-43 yqfQ S YqfQ-like protein
EHHHJOPM_01508 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EHHHJOPM_01509 2.8e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EHHHJOPM_01510 4.6e-36 yqfT S Protein of unknown function (DUF2624)
EHHHJOPM_01511 5.3e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
EHHHJOPM_01512 2.9e-72 zur P Belongs to the Fur family
EHHHJOPM_01513 3.2e-109 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
EHHHJOPM_01514 2.3e-52 yqfX S membrane
EHHHJOPM_01515 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHHHJOPM_01516 3.1e-47 yqfZ M LysM domain
EHHHJOPM_01517 1.8e-128 yqgB S Protein of unknown function (DUF1189)
EHHHJOPM_01518 2.2e-71 yqgC S protein conserved in bacteria
EHHHJOPM_01519 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
EHHHJOPM_01520 3.4e-228 yqgE EGP Major facilitator superfamily
EHHHJOPM_01521 0.0 pbpA 3.4.16.4 M penicillin-binding protein
EHHHJOPM_01522 8.4e-157 pstS P Phosphate
EHHHJOPM_01523 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
EHHHJOPM_01524 2.9e-154 pstA P Phosphate transport system permease
EHHHJOPM_01525 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EHHHJOPM_01526 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EHHHJOPM_01527 1.1e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHHHJOPM_01528 1.2e-50 yqzD
EHHHJOPM_01529 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EHHHJOPM_01530 4.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHHHJOPM_01531 4e-07 yqgO
EHHHJOPM_01532 1e-230 nhaC C Na H antiporter
EHHHJOPM_01533 2.2e-179 glcK 2.7.1.2 G Glucokinase
EHHHJOPM_01534 1.2e-216 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
EHHHJOPM_01535 4.3e-197 yqgU
EHHHJOPM_01536 6.9e-50 yqgV S Thiamine-binding protein
EHHHJOPM_01537 5.4e-20 yqgW S Protein of unknown function (DUF2759)
EHHHJOPM_01538 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EHHHJOPM_01539 3.1e-37 yqgY S Protein of unknown function (DUF2626)
EHHHJOPM_01540 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
EHHHJOPM_01542 6.5e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHHHJOPM_01543 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EHHHJOPM_01544 4.5e-185 corA P Mg2 transporter protein
EHHHJOPM_01545 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHHHJOPM_01546 7.8e-183 comGB NU COG1459 Type II secretory pathway, component PulF
EHHHJOPM_01547 8.9e-50 comGC U Required for transformation and DNA binding
EHHHJOPM_01548 8.4e-70 gspH NU Tfp pilus assembly protein FimT
EHHHJOPM_01549 2.6e-20 comGE
EHHHJOPM_01550 1.3e-64 comGF U Putative Competence protein ComGF
EHHHJOPM_01551 6.1e-61 S ComG operon protein 7
EHHHJOPM_01552 2.3e-26 yqzE S YqzE-like protein
EHHHJOPM_01553 1.1e-53 yqzG S Protein of unknown function (DUF3889)
EHHHJOPM_01554 1.2e-120 yqxM
EHHHJOPM_01555 3.5e-71 sipW 3.4.21.89 U Signal peptidase
EHHHJOPM_01556 4.7e-140 tasA S Cell division protein FtsN
EHHHJOPM_01557 7.8e-55 sinR K transcriptional
EHHHJOPM_01558 5.2e-23 sinI S Anti-repressor SinI
EHHHJOPM_01559 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
EHHHJOPM_01560 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
EHHHJOPM_01561 3.9e-209 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
EHHHJOPM_01562 3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHHHJOPM_01563 1.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHHHJOPM_01564 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
EHHHJOPM_01565 7.5e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EHHHJOPM_01566 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EHHHJOPM_01567 2e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
EHHHJOPM_01568 5.8e-62 yqhP
EHHHJOPM_01569 8e-174 yqhQ S Protein of unknown function (DUF1385)
EHHHJOPM_01570 7e-87 yqhR S Conserved membrane protein YqhR
EHHHJOPM_01571 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EHHHJOPM_01572 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHHHJOPM_01573 1.8e-36 yqhV S Protein of unknown function (DUF2619)
EHHHJOPM_01574 2.1e-171 spoIIIAA S stage III sporulation protein AA
EHHHJOPM_01575 1.6e-83 spoIIIAB S Stage III sporulation protein
EHHHJOPM_01576 7.6e-29 spoIIIAC S stage III sporulation protein AC
EHHHJOPM_01577 2.5e-41 spoIIIAD S Stage III sporulation protein AD
EHHHJOPM_01578 6.3e-200 spoIIIAE S stage III sporulation protein AE
EHHHJOPM_01579 2.6e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
EHHHJOPM_01580 1.1e-116 spoIIIAG S stage III sporulation protein AG
EHHHJOPM_01581 2.5e-62 spoIIIAH S SpoIIIAH-like protein
EHHHJOPM_01582 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EHHHJOPM_01583 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EHHHJOPM_01584 8.1e-67 yqhY S protein conserved in bacteria
EHHHJOPM_01585 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHHHJOPM_01586 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHHHJOPM_01587 1.8e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EHHHJOPM_01588 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EHHHJOPM_01589 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EHHHJOPM_01590 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHHHJOPM_01591 1.3e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
EHHHJOPM_01592 3.9e-78 argR K Regulates arginine biosynthesis genes
EHHHJOPM_01593 7.9e-305 recN L May be involved in recombinational repair of damaged DNA
EHHHJOPM_01594 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
EHHHJOPM_01595 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EHHHJOPM_01596 2.6e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHHHJOPM_01599 4.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EHHHJOPM_01601 1.2e-112 K Protein of unknown function (DUF1232)
EHHHJOPM_01602 7.7e-101 ytaF P Probably functions as a manganese efflux pump
EHHHJOPM_01603 2.1e-16
EHHHJOPM_01604 8.8e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
EHHHJOPM_01605 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EHHHJOPM_01606 1.6e-211 mmgA 2.3.1.9 I Belongs to the thiolase family
EHHHJOPM_01607 1.1e-153 hbdA 1.1.1.157 I Dehydrogenase
EHHHJOPM_01608 5.3e-201 mmgC I acyl-CoA dehydrogenase
EHHHJOPM_01609 1.6e-202 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
EHHHJOPM_01610 9.2e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
EHHHJOPM_01611 4.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHHHJOPM_01612 3.2e-34 yqzF S Protein of unknown function (DUF2627)
EHHHJOPM_01613 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
EHHHJOPM_01614 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
EHHHJOPM_01615 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
EHHHJOPM_01616 1.6e-205 buk 2.7.2.7 C Belongs to the acetokinase family
EHHHJOPM_01617 2.9e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHHHJOPM_01618 2.1e-161 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHHHJOPM_01619 3e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHHHJOPM_01620 2.6e-188 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHHHJOPM_01621 2e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EHHHJOPM_01622 1e-75 yqiW S Belongs to the UPF0403 family
EHHHJOPM_01623 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
EHHHJOPM_01624 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
EHHHJOPM_01625 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EHHHJOPM_01626 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
EHHHJOPM_01627 3.1e-95 yqjB S protein conserved in bacteria
EHHHJOPM_01629 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
EHHHJOPM_01630 1.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EHHHJOPM_01631 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
EHHHJOPM_01632 1.7e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EHHHJOPM_01633 2.4e-25 yqzJ
EHHHJOPM_01634 6.2e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHHHJOPM_01635 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHHHJOPM_01636 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EHHHJOPM_01637 6.1e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EHHHJOPM_01638 6.3e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EHHHJOPM_01639 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EHHHJOPM_01640 5.5e-50 S GlpM protein
EHHHJOPM_01641 1.1e-161 K LysR substrate binding domain
EHHHJOPM_01642 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
EHHHJOPM_01643 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EHHHJOPM_01646 1.7e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHHHJOPM_01647 1.1e-127 IQ reductase
EHHHJOPM_01648 0.0 pksJ Q Polyketide synthase of type I
EHHHJOPM_01649 0.0 1.1.1.320 Q Polyketide synthase of type I
EHHHJOPM_01650 0.0 Q Polyketide synthase of type I
EHHHJOPM_01651 0.0 pksJ Q Polyketide synthase of type I
EHHHJOPM_01652 0.0 pfaA Q Polyketide synthase of type I
EHHHJOPM_01653 0.0 Q Polyketide synthase of type I
EHHHJOPM_01654 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EHHHJOPM_01655 3.1e-220 eryK 1.14.13.154 C Cytochrome P450
EHHHJOPM_01656 1.7e-238 pksG 2.3.3.10 I synthase
EHHHJOPM_01657 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
EHHHJOPM_01658 6.9e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHHHJOPM_01659 8e-174 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
EHHHJOPM_01660 3.6e-140 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHHJOPM_01661 1.6e-249 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
EHHHJOPM_01662 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
EHHHJOPM_01663 5.6e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHHJOPM_01665 1.3e-185 yueF S transporter activity
EHHHJOPM_01667 1.4e-56 S YolD-like protein
EHHHJOPM_01668 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHHHJOPM_01669 8.7e-89 yqjY K acetyltransferase
EHHHJOPM_01670 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
EHHHJOPM_01671 1.2e-172 yqkA K GrpB protein
EHHHJOPM_01672 7.7e-61 yqkB S Belongs to the HesB IscA family
EHHHJOPM_01673 3.2e-39 yqkC S Protein of unknown function (DUF2552)
EHHHJOPM_01674 9e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
EHHHJOPM_01676 2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
EHHHJOPM_01678 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
EHHHJOPM_01679 4e-220 yqxK 3.6.4.12 L DNA helicase
EHHHJOPM_01680 3e-57 ansR K Transcriptional regulator
EHHHJOPM_01681 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
EHHHJOPM_01682 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
EHHHJOPM_01683 1.6e-239 mleN C Na H antiporter
EHHHJOPM_01684 3.8e-243 mleA 1.1.1.38 C malic enzyme
EHHHJOPM_01685 5.7e-22
EHHHJOPM_01686 1.5e-33 yqkK
EHHHJOPM_01688 1.2e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EHHHJOPM_01689 1.9e-80 fur P Belongs to the Fur family
EHHHJOPM_01690 3.7e-37 S Protein of unknown function (DUF4227)
EHHHJOPM_01691 2.8e-165 xerD L recombinase XerD
EHHHJOPM_01692 4.8e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHHHJOPM_01693 2.4e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHHHJOPM_01694 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
EHHHJOPM_01695 6.6e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
EHHHJOPM_01696 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EHHHJOPM_01697 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHHJOPM_01698 4.8e-111 spoVAA S Stage V sporulation protein AA
EHHHJOPM_01699 5.1e-60 spoVAB S Stage V sporulation protein AB
EHHHJOPM_01700 6e-79 spoVAC S stage V sporulation protein AC
EHHHJOPM_01701 1.2e-188 spoVAD I Stage V sporulation protein AD
EHHHJOPM_01702 5e-57 spoVAEB S stage V sporulation protein
EHHHJOPM_01703 5.2e-110 spoVAEA S stage V sporulation protein
EHHHJOPM_01704 3.2e-270 spoVAF EG Stage V sporulation protein AF
EHHHJOPM_01705 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EHHHJOPM_01706 1.9e-153 ypuA S Secreted protein
EHHHJOPM_01707 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHHHJOPM_01708 9.1e-81 ccdC1 O Protein of unknown function (DUF1453)
EHHHJOPM_01709 6.5e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EHHHJOPM_01710 6.4e-49 ypuD
EHHHJOPM_01711 1.2e-208 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHHHJOPM_01712 2.2e-111 ribE 2.5.1.9 H Riboflavin synthase
EHHHJOPM_01713 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHHHJOPM_01714 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EHHHJOPM_01715 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHHHJOPM_01716 1.7e-93 ypuF S Domain of unknown function (DUF309)
EHHHJOPM_01718 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EHHHJOPM_01719 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EHHHJOPM_01720 3.8e-93 ypuI S Protein of unknown function (DUF3907)
EHHHJOPM_01721 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
EHHHJOPM_01722 2e-103 spmA S Spore maturation protein
EHHHJOPM_01723 1.3e-88 spmB S Spore maturation protein
EHHHJOPM_01724 1.3e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EHHHJOPM_01725 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EHHHJOPM_01726 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
EHHHJOPM_01727 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EHHHJOPM_01728 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHHJOPM_01729 0.0 resE 2.7.13.3 T Histidine kinase
EHHHJOPM_01730 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
EHHHJOPM_01731 1.7e-191 rsiX
EHHHJOPM_01732 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHHHJOPM_01733 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EHHHJOPM_01734 3.6e-41 fer C Ferredoxin
EHHHJOPM_01735 1.5e-194 ypbB 5.1.3.1 S protein conserved in bacteria
EHHHJOPM_01736 3e-270 recQ 3.6.4.12 L DNA helicase
EHHHJOPM_01737 4e-99 ypbD S metal-dependent membrane protease
EHHHJOPM_01738 1.2e-74 ypbE M Lysin motif
EHHHJOPM_01739 5.7e-85 ypbF S Protein of unknown function (DUF2663)
EHHHJOPM_01740 7.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
EHHHJOPM_01741 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EHHHJOPM_01742 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
EHHHJOPM_01743 5e-187 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
EHHHJOPM_01744 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
EHHHJOPM_01745 3e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
EHHHJOPM_01746 1.5e-250 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
EHHHJOPM_01747 1.8e-60 ypfA M Flagellar protein YcgR
EHHHJOPM_01748 1.4e-12 S Family of unknown function (DUF5359)
EHHHJOPM_01749 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EHHHJOPM_01750 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
EHHHJOPM_01751 1.7e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EHHHJOPM_01752 4.7e-08 S YpzI-like protein
EHHHJOPM_01753 2.1e-103 yphA
EHHHJOPM_01754 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EHHHJOPM_01755 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EHHHJOPM_01756 3.3e-16 yphE S Protein of unknown function (DUF2768)
EHHHJOPM_01757 3.1e-133 yphF
EHHHJOPM_01758 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EHHHJOPM_01759 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EHHHJOPM_01760 2.1e-100 folE 3.5.4.16 H GTP cyclohydrolase
EHHHJOPM_01761 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EHHHJOPM_01762 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EHHHJOPM_01763 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EHHHJOPM_01764 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EHHHJOPM_01765 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EHHHJOPM_01766 1.1e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
EHHHJOPM_01767 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHHHJOPM_01768 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHHHJOPM_01769 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EHHHJOPM_01770 1.2e-288 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHHHJOPM_01771 1.5e-154 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHHHJOPM_01772 1.2e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EHHHJOPM_01773 7.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
EHHHJOPM_01774 2.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EHHHJOPM_01775 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EHHHJOPM_01776 1.9e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHHHJOPM_01777 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EHHHJOPM_01778 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EHHHJOPM_01779 5.9e-233 S COG0457 FOG TPR repeat
EHHHJOPM_01780 2.1e-99 ypiB S Belongs to the UPF0302 family
EHHHJOPM_01781 2.7e-76 ypiF S Protein of unknown function (DUF2487)
EHHHJOPM_01782 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
EHHHJOPM_01783 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
EHHHJOPM_01784 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
EHHHJOPM_01785 2.9e-105 ypjA S membrane
EHHHJOPM_01786 9.5e-141 ypjB S sporulation protein
EHHHJOPM_01787 2.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
EHHHJOPM_01788 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
EHHHJOPM_01789 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
EHHHJOPM_01790 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EHHHJOPM_01791 1.2e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
EHHHJOPM_01792 4.3e-132 bshB1 S proteins, LmbE homologs
EHHHJOPM_01793 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
EHHHJOPM_01794 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EHHHJOPM_01795 6.2e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EHHHJOPM_01796 6.6e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EHHHJOPM_01797 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHHHJOPM_01798 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EHHHJOPM_01799 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EHHHJOPM_01800 6.7e-23 ypmA S Protein of unknown function (DUF4264)
EHHHJOPM_01801 1.5e-80 ypmB S protein conserved in bacteria
EHHHJOPM_01802 1.8e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EHHHJOPM_01803 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
EHHHJOPM_01804 3e-130 dnaD L DNA replication protein DnaD
EHHHJOPM_01805 7.1e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHHHJOPM_01806 2.5e-91 ypoC
EHHHJOPM_01807 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EHHHJOPM_01808 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EHHHJOPM_01809 2.6e-188 yppC S Protein of unknown function (DUF2515)
EHHHJOPM_01812 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
EHHHJOPM_01814 2.1e-49 yppG S YppG-like protein
EHHHJOPM_01815 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
EHHHJOPM_01816 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
EHHHJOPM_01817 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EHHHJOPM_01818 1.6e-219 yprB L RNase_H superfamily
EHHHJOPM_01820 9.9e-33 cotD S Inner spore coat protein D
EHHHJOPM_01821 4.1e-98 ypsA S Belongs to the UPF0398 family
EHHHJOPM_01822 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EHHHJOPM_01823 2.6e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EHHHJOPM_01824 6.5e-78 yqgA
EHHHJOPM_01825 6.6e-22 S YpzG-like protein
EHHHJOPM_01827 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
EHHHJOPM_01828 4.3e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EHHHJOPM_01829 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EHHHJOPM_01830 2.2e-235 pbuX F xanthine
EHHHJOPM_01832 1.9e-98 yrdC 3.5.1.19 Q Isochorismatase family
EHHHJOPM_01833 1.2e-56 ydfR S Protein of unknown function (DUF421)
EHHHJOPM_01834 3.9e-22 ydfR S Protein of unknown function (DUF421)
EHHHJOPM_01836 6e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
EHHHJOPM_01837 4.5e-106 J Acetyltransferase (GNAT) domain
EHHHJOPM_01838 6.1e-202 bcsA Q Naringenin-chalcone synthase
EHHHJOPM_01839 1.1e-89 ypbQ S protein conserved in bacteria
EHHHJOPM_01840 0.0 ypbR S Dynamin family
EHHHJOPM_01841 2.2e-38 ypbS S Protein of unknown function (DUF2533)
EHHHJOPM_01843 1e-162 polA 2.7.7.7 L 5'3' exonuclease
EHHHJOPM_01845 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
EHHHJOPM_01846 2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EHHHJOPM_01847 2e-123 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
EHHHJOPM_01848 1.5e-28 ypeQ S Zinc-finger
EHHHJOPM_01849 6.1e-36 S Protein of unknown function (DUF2564)
EHHHJOPM_01850 1.3e-11 degR
EHHHJOPM_01851 1e-30 cspD K Cold-shock protein
EHHHJOPM_01852 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EHHHJOPM_01853 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EHHHJOPM_01854 2.4e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
EHHHJOPM_01855 3.1e-99 ypgQ S phosphohydrolase
EHHHJOPM_01856 1.7e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
EHHHJOPM_01857 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EHHHJOPM_01858 1.1e-74 yphP S Belongs to the UPF0403 family
EHHHJOPM_01859 3.3e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
EHHHJOPM_01860 8.5e-113 ypjP S YpjP-like protein
EHHHJOPM_01861 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHHHJOPM_01862 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHHHJOPM_01863 6.1e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EHHHJOPM_01864 1.6e-109 hlyIII S protein, Hemolysin III
EHHHJOPM_01865 8.3e-174 pspF K Transcriptional regulator
EHHHJOPM_01866 3.7e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EHHHJOPM_01867 3.2e-37 ypmP S Protein of unknown function (DUF2535)
EHHHJOPM_01868 7.4e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EHHHJOPM_01869 6.4e-134 ypmR E GDSL-like Lipase/Acylhydrolase
EHHHJOPM_01870 6.1e-97 ypmS S protein conserved in bacteria
EHHHJOPM_01871 1.4e-66 ypoP K transcriptional
EHHHJOPM_01872 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHHHJOPM_01873 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
EHHHJOPM_01874 5.3e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
EHHHJOPM_01875 2.6e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
EHHHJOPM_01876 1.4e-178 cgeB S Spore maturation protein
EHHHJOPM_01877 1.6e-52 cgeA
EHHHJOPM_01878 1.2e-40 cgeC
EHHHJOPM_01879 2e-241 cgeD M maturation of the outermost layer of the spore
EHHHJOPM_01880 1.4e-144 yiiD K acetyltransferase
EHHHJOPM_01882 1.5e-20 yosT L Bacterial transcription activator, effector binding domain
EHHHJOPM_01883 3.5e-244 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHHHJOPM_01884 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EHHHJOPM_01885 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EHHHJOPM_01886 9e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
EHHHJOPM_01887 9.8e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
EHHHJOPM_01888 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
EHHHJOPM_01889 9.2e-46 yokU S YokU-like protein, putative antitoxin
EHHHJOPM_01890 9.1e-36 yozE S Belongs to the UPF0346 family
EHHHJOPM_01891 2.6e-24 E lactoylglutathione lyase activity
EHHHJOPM_01892 1.7e-125 yodN
EHHHJOPM_01894 6.2e-24 yozD S YozD-like protein
EHHHJOPM_01895 1.4e-102 yodM 3.6.1.27 I Acid phosphatase homologues
EHHHJOPM_01896 3.3e-55 yodL S YodL-like
EHHHJOPM_01898 1.3e-125 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
EHHHJOPM_01899 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EHHHJOPM_01900 6.5e-22 yodI
EHHHJOPM_01901 7e-127 yodH Q Methyltransferase
EHHHJOPM_01902 7.9e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
EHHHJOPM_01903 9.8e-132 yydK K Transcriptional regulator
EHHHJOPM_01904 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EHHHJOPM_01905 1e-276 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
EHHHJOPM_01906 1.1e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHHHJOPM_01907 1.4e-19 S Protein of unknown function (DUF3311)
EHHHJOPM_01908 2.2e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
EHHHJOPM_01909 5.7e-109 mhqD S Carboxylesterase
EHHHJOPM_01910 2.9e-105 yodC C nitroreductase
EHHHJOPM_01911 3e-56 yodB K transcriptional
EHHHJOPM_01912 2.3e-68 yoaQ S Evidence 4 Homologs of previously reported genes of
EHHHJOPM_01913 5.9e-67 yodA S tautomerase
EHHHJOPM_01915 7.3e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
EHHHJOPM_01916 3.3e-161 rarD S -transporter
EHHHJOPM_01917 4.9e-23
EHHHJOPM_01918 3.7e-60 yojF S Protein of unknown function (DUF1806)
EHHHJOPM_01919 5.6e-126 yojG S deacetylase
EHHHJOPM_01920 2.5e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHHHJOPM_01921 6.1e-236 norM V Multidrug efflux pump
EHHHJOPM_01923 8.2e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EHHHJOPM_01924 5.8e-222 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
EHHHJOPM_01925 5.2e-226 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EHHHJOPM_01926 1.9e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EHHHJOPM_01927 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
EHHHJOPM_01928 0.0 yojO P Von Willebrand factor
EHHHJOPM_01929 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EHHHJOPM_01930 2.1e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EHHHJOPM_01931 8.5e-139 S Metallo-beta-lactamase superfamily
EHHHJOPM_01932 2.5e-159 yocS S -transporter
EHHHJOPM_01933 1.9e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EHHHJOPM_01934 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
EHHHJOPM_01935 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
EHHHJOPM_01936 9.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
EHHHJOPM_01937 3.6e-31 yozC
EHHHJOPM_01939 2.4e-56 yozO S Bacterial PH domain
EHHHJOPM_01940 8.5e-37 yocN
EHHHJOPM_01941 3.8e-44 yozN
EHHHJOPM_01942 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
EHHHJOPM_01943 7.5e-09
EHHHJOPM_01944 1e-09 yocL
EHHHJOPM_01945 8.6e-55 dksA T general stress protein
EHHHJOPM_01947 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHHHJOPM_01948 0.0 recQ 3.6.4.12 L DNA helicase
EHHHJOPM_01949 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
EHHHJOPM_01951 1.6e-185 yocD 3.4.17.13 V peptidase S66
EHHHJOPM_01952 1.6e-93 yocC
EHHHJOPM_01953 5.2e-139 yocB J Protein required for attachment to host cells
EHHHJOPM_01954 3.6e-91 yozB S membrane
EHHHJOPM_01955 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EHHHJOPM_01956 8.4e-54 czrA K transcriptional
EHHHJOPM_01957 7.1e-92 yobW
EHHHJOPM_01958 7.2e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
EHHHJOPM_01959 1.2e-92 yobS K Transcriptional regulator
EHHHJOPM_01960 4.3e-132 yobQ K helix_turn_helix, arabinose operon control protein
EHHHJOPM_01961 1.2e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
EHHHJOPM_01962 6.4e-60 ykvN K Transcriptional regulator
EHHHJOPM_01963 1.1e-130 IQ Enoyl-(Acyl carrier protein) reductase
EHHHJOPM_01964 7.4e-43
EHHHJOPM_01965 1.5e-95 hpr K helix_turn_helix multiple antibiotic resistance protein
EHHHJOPM_01967 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EHHHJOPM_01968 4.8e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHHHJOPM_01969 3.8e-268 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
EHHHJOPM_01970 2.4e-202 yoaB EGP Major facilitator Superfamily
EHHHJOPM_01971 1.9e-133 yoxB
EHHHJOPM_01972 1.4e-39 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EHHHJOPM_01973 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHHJOPM_01974 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EHHHJOPM_01975 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHHHJOPM_01976 9e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHHHJOPM_01977 4.5e-150 gltC K Transcriptional regulator
EHHHJOPM_01978 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
EHHHJOPM_01979 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EHHHJOPM_01981 1.1e-181 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
EHHHJOPM_01982 4.1e-153 gltR1 K Transcriptional regulator
EHHHJOPM_01984 1.8e-50 ybzH K Helix-turn-helix domain
EHHHJOPM_01985 3.4e-198 ybcL EGP Major facilitator Superfamily
EHHHJOPM_01986 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
EHHHJOPM_01987 1.8e-34 yoeD G Helix-turn-helix domain
EHHHJOPM_01988 3.5e-97 L Integrase
EHHHJOPM_01990 2.9e-96 yoeB S IseA DL-endopeptidase inhibitor
EHHHJOPM_01991 3.3e-245 yoeA V MATE efflux family protein
EHHHJOPM_01992 7.8e-185 yoxA 5.1.3.3 G Aldose 1-epimerase
EHHHJOPM_01993 5.6e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
EHHHJOPM_01994 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_01995 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_01996 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_01997 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_01998 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
EHHHJOPM_01999 1.6e-64 yngL S Protein of unknown function (DUF1360)
EHHHJOPM_02000 7.3e-302 yngK T Glycosyl hydrolase-like 10
EHHHJOPM_02001 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
EHHHJOPM_02002 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EHHHJOPM_02003 7.9e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
EHHHJOPM_02004 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
EHHHJOPM_02005 3.6e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
EHHHJOPM_02006 7.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
EHHHJOPM_02007 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EHHHJOPM_02008 3.2e-104 yngC S SNARE associated Golgi protein
EHHHJOPM_02009 2.6e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EHHHJOPM_02010 9.6e-68 yngA S membrane
EHHHJOPM_02011 1.5e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EHHHJOPM_02012 3.6e-257 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EHHHJOPM_02013 3.1e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EHHHJOPM_02014 4.1e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EHHHJOPM_02015 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHHHJOPM_02016 1.2e-216 bioI 1.14.14.46 C Cytochrome P450
EHHHJOPM_02017 1.2e-250 yxjC EG COG2610 H gluconate symporter and related permeases
EHHHJOPM_02018 9.9e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EHHHJOPM_02019 5.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EHHHJOPM_02020 2.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EHHHJOPM_02021 7.3e-217 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EHHHJOPM_02022 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_02023 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_02024 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_02025 1.4e-292 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
EHHHJOPM_02026 2.8e-251 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
EHHHJOPM_02027 8.4e-128 T Transcriptional regulatory protein, C terminal
EHHHJOPM_02028 2.3e-230 T PhoQ Sensor
EHHHJOPM_02029 1.5e-49 S Domain of unknown function (DUF4870)
EHHHJOPM_02030 5.4e-286 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
EHHHJOPM_02031 5.7e-25 S Platelet-activating factor acetylhydrolase, isoform II
EHHHJOPM_02032 1.8e-61 S Platelet-activating factor acetylhydrolase, isoform II
EHHHJOPM_02033 7.4e-297 yndJ S YndJ-like protein
EHHHJOPM_02034 1.6e-79 yndH S Domain of unknown function (DUF4166)
EHHHJOPM_02035 5.4e-155 yndG S DoxX-like family
EHHHJOPM_02036 9.2e-218 exuT G Sugar (and other) transporter
EHHHJOPM_02037 1.7e-179 kdgR_1 K transcriptional
EHHHJOPM_02038 1.1e-145 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EHHHJOPM_02039 4.7e-131 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
EHHHJOPM_02040 1e-56 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
EHHHJOPM_02041 1.5e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
EHHHJOPM_02042 1.4e-119 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
EHHHJOPM_02043 2.6e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
EHHHJOPM_02044 1.2e-245 agcS E Sodium alanine symporter
EHHHJOPM_02045 5.1e-41 ynfC
EHHHJOPM_02046 6e-13
EHHHJOPM_02047 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EHHHJOPM_02048 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EHHHJOPM_02049 3.3e-68 yccU S CoA-binding protein
EHHHJOPM_02050 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EHHHJOPM_02051 1.1e-49 yneR S Belongs to the HesB IscA family
EHHHJOPM_02052 1.4e-52 yneQ
EHHHJOPM_02053 8.3e-75 yneP S Thioesterase-like superfamily
EHHHJOPM_02054 7.1e-18 tlp S Belongs to the Tlp family
EHHHJOPM_02056 8.2e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EHHHJOPM_02057 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EHHHJOPM_02058 7.5e-15 sspO S Belongs to the SspO family
EHHHJOPM_02059 2.3e-19 sspP S Belongs to the SspP family
EHHHJOPM_02060 1.1e-62 hspX O Spore coat protein
EHHHJOPM_02061 2.5e-74 yneK S Protein of unknown function (DUF2621)
EHHHJOPM_02062 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
EHHHJOPM_02063 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
EHHHJOPM_02064 1.7e-125 ccdA O cytochrome c biogenesis protein
EHHHJOPM_02065 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
EHHHJOPM_02066 2.3e-28 yneF S UPF0154 protein
EHHHJOPM_02067 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
EHHHJOPM_02068 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHHHJOPM_02069 9.8e-33 ynzC S UPF0291 protein
EHHHJOPM_02070 5e-111 yneB L resolvase
EHHHJOPM_02071 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EHHHJOPM_02072 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHHHJOPM_02073 2.1e-12 yoaW
EHHHJOPM_02074 1.2e-71 yndM S Protein of unknown function (DUF2512)
EHHHJOPM_02075 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
EHHHJOPM_02076 9.1e-08
EHHHJOPM_02077 2.9e-140 yndL S Replication protein
EHHHJOPM_02078 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
EHHHJOPM_02079 0.0 yobO M Pectate lyase superfamily protein
EHHHJOPM_02081 1.9e-92 yvgO
EHHHJOPM_02082 3.4e-65 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EHHHJOPM_02084 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
EHHHJOPM_02085 3.9e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHHJOPM_02086 5.6e-115 ynaE S Domain of unknown function (DUF3885)
EHHHJOPM_02087 1.6e-99 J Acetyltransferase (GNAT) domain
EHHHJOPM_02088 2.4e-144 yoaP 3.1.3.18 K YoaP-like
EHHHJOPM_02090 1e-09
EHHHJOPM_02091 3.7e-185 adhP 1.1.1.1 C alcohol dehydrogenase
EHHHJOPM_02092 4.5e-67 S DinB family
EHHHJOPM_02093 8.9e-122 K WYL domain
EHHHJOPM_02094 7e-17
EHHHJOPM_02099 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
EHHHJOPM_02100 7.1e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
EHHHJOPM_02102 1e-259 xylA 5.3.1.5 G Belongs to the xylose isomerase family
EHHHJOPM_02103 3.2e-209 xylR GK ROK family
EHHHJOPM_02104 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
EHHHJOPM_02105 4.9e-249 xynT G MFS/sugar transport protein
EHHHJOPM_02106 3.3e-208 mrjp G Major royal jelly protein
EHHHJOPM_02107 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
EHHHJOPM_02108 4.3e-68 glnR K transcriptional
EHHHJOPM_02109 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EHHHJOPM_02110 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHHHJOPM_02111 1.3e-176 spoVK O stage V sporulation protein K
EHHHJOPM_02112 1.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EHHHJOPM_02113 7.6e-109 ymaB S MutT family
EHHHJOPM_02114 1.4e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHHHJOPM_02115 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHHHJOPM_02116 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
EHHHJOPM_02117 1.8e-20 ymzA
EHHHJOPM_02118 3e-41
EHHHJOPM_02119 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EHHHJOPM_02120 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHHHJOPM_02121 3.6e-43 ymaF S YmaF family
EHHHJOPM_02123 2.6e-47 ebrA P Small Multidrug Resistance protein
EHHHJOPM_02124 2.6e-53 ebrB P Small Multidrug Resistance protein
EHHHJOPM_02125 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
EHHHJOPM_02126 8.7e-125 ymaC S Replication protein
EHHHJOPM_02128 7.5e-255 aprX O Belongs to the peptidase S8 family
EHHHJOPM_02129 4.1e-62 ymzB
EHHHJOPM_02130 3.6e-118 yoaK S Membrane
EHHHJOPM_02131 1.9e-77 nucB M Deoxyribonuclease NucA/NucB
EHHHJOPM_02132 1.7e-229 cypA C Cytochrome P450
EHHHJOPM_02133 0.0 pks13 HQ Beta-ketoacyl synthase
EHHHJOPM_02134 0.0 dhbF IQ polyketide synthase
EHHHJOPM_02135 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
EHHHJOPM_02136 0.0 Q Polyketide synthase of type I
EHHHJOPM_02137 0.0 rhiB IQ polyketide synthase
EHHHJOPM_02138 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
EHHHJOPM_02139 5.9e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
EHHHJOPM_02140 5.3e-242 pksG 2.3.3.10 I synthase
EHHHJOPM_02141 5.5e-34 acpK IQ Phosphopantetheine attachment site
EHHHJOPM_02142 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EHHHJOPM_02143 1.1e-183 pksD Q Acyl transferase domain
EHHHJOPM_02144 2.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EHHHJOPM_02145 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
EHHHJOPM_02147 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHHHJOPM_02148 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHHHJOPM_02149 1.7e-88 cotE S Spore coat protein
EHHHJOPM_02150 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EHHHJOPM_02151 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHHHJOPM_02152 1.3e-213 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EHHHJOPM_02153 4.5e-194 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EHHHJOPM_02154 1.2e-36 spoVS S Stage V sporulation protein S
EHHHJOPM_02155 4.9e-153 ymdB S protein conserved in bacteria
EHHHJOPM_02156 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
EHHHJOPM_02157 1.9e-193 pbpX V Beta-lactamase
EHHHJOPM_02158 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHHHJOPM_02159 2.7e-230 cinA 3.5.1.42 S Belongs to the CinA family
EHHHJOPM_02160 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHHHJOPM_02161 7.1e-124 ymfM S protein conserved in bacteria
EHHHJOPM_02162 1e-142 ymfK S Protein of unknown function (DUF3388)
EHHHJOPM_02163 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
EHHHJOPM_02164 1.2e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EHHHJOPM_02165 3.5e-241 ymfH S zinc protease
EHHHJOPM_02166 1.3e-235 ymfF S Peptidase M16
EHHHJOPM_02167 0.0 ydgH S drug exporters of the RND superfamily
EHHHJOPM_02168 4.3e-77 K helix_turn_helix multiple antibiotic resistance protein
EHHHJOPM_02169 3e-227 ymfD EGP Major facilitator Superfamily
EHHHJOPM_02170 1.2e-132 ymfC K Transcriptional regulator
EHHHJOPM_02171 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EHHHJOPM_02172 6.3e-31 S YlzJ-like protein
EHHHJOPM_02173 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
EHHHJOPM_02174 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHHHJOPM_02175 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHHHJOPM_02176 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
EHHHJOPM_02177 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHHHJOPM_02178 6.4e-105 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EHHHJOPM_02179 1e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
EHHHJOPM_02180 2.6e-42 ymxH S YlmC YmxH family
EHHHJOPM_02181 1.2e-233 pepR S Belongs to the peptidase M16 family
EHHHJOPM_02182 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
EHHHJOPM_02183 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EHHHJOPM_02184 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHHHJOPM_02185 4.6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EHHHJOPM_02186 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHHHJOPM_02187 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHHHJOPM_02188 3.9e-44 ylxP S protein conserved in bacteria
EHHHJOPM_02189 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHHHJOPM_02190 1.8e-47 ylxQ J ribosomal protein
EHHHJOPM_02191 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
EHHHJOPM_02192 5.4e-206 nusA K Participates in both transcription termination and antitermination
EHHHJOPM_02193 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
EHHHJOPM_02194 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHHHJOPM_02195 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EHHHJOPM_02196 1.5e-233 rasP M zinc metalloprotease
EHHHJOPM_02197 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EHHHJOPM_02198 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
EHHHJOPM_02199 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHHHJOPM_02200 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EHHHJOPM_02201 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EHHHJOPM_02202 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHHHJOPM_02203 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
EHHHJOPM_02204 8e-50 ylxL
EHHHJOPM_02205 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHHJOPM_02206 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EHHHJOPM_02207 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EHHHJOPM_02208 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
EHHHJOPM_02209 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
EHHHJOPM_02210 2.1e-191 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EHHHJOPM_02211 1.6e-155 flhG D Belongs to the ParA family
EHHHJOPM_02212 8.2e-191 flhF N Flagellar biosynthesis regulator FlhF
EHHHJOPM_02213 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHHHJOPM_02214 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHHHJOPM_02215 5.2e-131 fliR N Flagellar biosynthetic protein FliR
EHHHJOPM_02216 2e-37 fliQ N Role in flagellar biosynthesis
EHHHJOPM_02217 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
EHHHJOPM_02218 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
EHHHJOPM_02219 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
EHHHJOPM_02220 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHHHJOPM_02221 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EHHHJOPM_02222 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
EHHHJOPM_02223 5.7e-138 flgG N Flagellar basal body rod
EHHHJOPM_02224 4.1e-72 flgD N Flagellar basal body rod modification protein
EHHHJOPM_02225 1e-203 fliK N Flagellar hook-length control protein
EHHHJOPM_02226 1.3e-47 ylxF S MgtE intracellular N domain
EHHHJOPM_02227 2e-71 fliJ N Flagellar biosynthesis chaperone
EHHHJOPM_02228 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EHHHJOPM_02229 2e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
EHHHJOPM_02230 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EHHHJOPM_02231 1.4e-263 fliF N The M ring may be actively involved in energy transduction
EHHHJOPM_02232 2.5e-31 fliE N Flagellar hook-basal body
EHHHJOPM_02233 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
EHHHJOPM_02234 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EHHHJOPM_02235 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EHHHJOPM_02236 4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHHHJOPM_02237 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHHHJOPM_02238 7.2e-172 xerC L tyrosine recombinase XerC
EHHHJOPM_02239 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EHHHJOPM_02240 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHHHJOPM_02241 1.6e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
EHHHJOPM_02242 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EHHHJOPM_02243 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EHHHJOPM_02244 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
EHHHJOPM_02245 7.8e-305 ylqG
EHHHJOPM_02246 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHHHJOPM_02247 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHHHJOPM_02248 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EHHHJOPM_02249 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EHHHJOPM_02250 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHHHJOPM_02251 1.3e-61 ylqD S YlqD protein
EHHHJOPM_02252 1.7e-35 ylqC S Belongs to the UPF0109 family
EHHHJOPM_02253 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EHHHJOPM_02254 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHHHJOPM_02255 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EHHHJOPM_02256 2.6e-138 S Phosphotransferase enzyme family
EHHHJOPM_02257 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EHHHJOPM_02258 0.0 smc D Required for chromosome condensation and partitioning
EHHHJOPM_02259 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EHHHJOPM_02260 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHHHJOPM_02261 4.6e-129 IQ reductase
EHHHJOPM_02262 2e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EHHHJOPM_02263 1.4e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EHHHJOPM_02264 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EHHHJOPM_02265 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHHHJOPM_02266 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
EHHHJOPM_02267 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
EHHHJOPM_02268 3.2e-303 yloV S kinase related to dihydroxyacetone kinase
EHHHJOPM_02269 5.5e-59 asp S protein conserved in bacteria
EHHHJOPM_02270 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EHHHJOPM_02271 1.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
EHHHJOPM_02272 5.2e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EHHHJOPM_02273 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EHHHJOPM_02274 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
EHHHJOPM_02275 2.3e-139 stp 3.1.3.16 T phosphatase
EHHHJOPM_02276 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EHHHJOPM_02277 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHHHJOPM_02278 1.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHHHJOPM_02279 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EHHHJOPM_02280 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHHHJOPM_02281 7.4e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHHHJOPM_02282 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EHHHJOPM_02283 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EHHHJOPM_02284 1.5e-40 ylzA S Belongs to the UPF0296 family
EHHHJOPM_02285 8.5e-154 yloC S stress-induced protein
EHHHJOPM_02286 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
EHHHJOPM_02287 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EHHHJOPM_02288 9.3e-78 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
EHHHJOPM_02289 5.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
EHHHJOPM_02290 4.5e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EHHHJOPM_02291 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
EHHHJOPM_02292 7.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
EHHHJOPM_02293 1.1e-176 cysP P phosphate transporter
EHHHJOPM_02294 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
EHHHJOPM_02296 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHHHJOPM_02297 6.1e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EHHHJOPM_02298 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EHHHJOPM_02299 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EHHHJOPM_02300 0.0 carB 6.3.5.5 F Belongs to the CarB family
EHHHJOPM_02301 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EHHHJOPM_02302 4.7e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EHHHJOPM_02303 2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EHHHJOPM_02304 3e-232 pyrP F Xanthine uracil
EHHHJOPM_02305 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EHHHJOPM_02306 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EHHHJOPM_02307 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHHHJOPM_02308 1.2e-61 dksA T COG1734 DnaK suppressor protein
EHHHJOPM_02309 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHHHJOPM_02310 8.9e-68 divIVA D Cell division initiation protein
EHHHJOPM_02311 1.6e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
EHHHJOPM_02312 5.2e-41 yggT S membrane
EHHHJOPM_02313 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EHHHJOPM_02314 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHHHJOPM_02315 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
EHHHJOPM_02316 2.2e-38 ylmC S sporulation protein
EHHHJOPM_02317 4.7e-254 argE 3.5.1.16 E Acetylornithine deacetylase
EHHHJOPM_02318 5.5e-144 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EHHHJOPM_02319 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHHJOPM_02320 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHHJOPM_02321 1e-157 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EHHHJOPM_02322 0.0 bpr O COG1404 Subtilisin-like serine proteases
EHHHJOPM_02323 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHHHJOPM_02324 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EHHHJOPM_02325 4.5e-130 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EHHHJOPM_02326 3.7e-168 murB 1.3.1.98 M cell wall formation
EHHHJOPM_02327 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHHHJOPM_02328 2.2e-185 spoVE D Belongs to the SEDS family
EHHHJOPM_02329 8.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHHHJOPM_02330 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHHHJOPM_02331 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHHHJOPM_02332 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
EHHHJOPM_02333 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
EHHHJOPM_02334 2.9e-52 ftsL D Essential cell division protein
EHHHJOPM_02335 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EHHHJOPM_02336 1.2e-77 mraZ K Belongs to the MraZ family
EHHHJOPM_02337 4.8e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EHHHJOPM_02338 1e-162 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHHHJOPM_02339 1.2e-88 ylbP K n-acetyltransferase
EHHHJOPM_02340 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EHHHJOPM_02341 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EHHHJOPM_02342 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
EHHHJOPM_02343 4.3e-228 ylbM S Belongs to the UPF0348 family
EHHHJOPM_02344 1.6e-188 ylbL T Belongs to the peptidase S16 family
EHHHJOPM_02345 4.4e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
EHHHJOPM_02346 2.2e-216 ylbJ S Sporulation integral membrane protein YlbJ
EHHHJOPM_02347 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHHHJOPM_02348 6e-97 rsmD 2.1.1.171 L Methyltransferase
EHHHJOPM_02350 5.5e-43 ylbG S UPF0298 protein
EHHHJOPM_02351 1.2e-71 ylbF S Belongs to the UPF0342 family
EHHHJOPM_02352 8.8e-37 ylbE S YlbE-like protein
EHHHJOPM_02353 7.9e-54 ylbD S Putative coat protein
EHHHJOPM_02354 4.6e-199 ylbC S protein with SCP PR1 domains
EHHHJOPM_02355 2.2e-73 ylbB T COG0517 FOG CBS domain
EHHHJOPM_02356 3.2e-59 ylbA S YugN-like family
EHHHJOPM_02357 2e-163 ctaG S cytochrome c oxidase
EHHHJOPM_02358 1e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EHHHJOPM_02359 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EHHHJOPM_02360 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHHHJOPM_02361 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EHHHJOPM_02362 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EHHHJOPM_02363 5.9e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EHHHJOPM_02364 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EHHHJOPM_02365 1.9e-212 ftsW D Belongs to the SEDS family
EHHHJOPM_02366 8.7e-44 ylaN S Belongs to the UPF0358 family
EHHHJOPM_02367 1.3e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
EHHHJOPM_02368 8.5e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EHHHJOPM_02369 3e-243 phoH T ATPase related to phosphate starvation-inducible protein PhoH
EHHHJOPM_02370 2.6e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHHHJOPM_02371 1.4e-33 ylaI S protein conserved in bacteria
EHHHJOPM_02372 6.6e-48 ylaH S YlaH-like protein
EHHHJOPM_02373 0.0 typA T GTP-binding protein TypA
EHHHJOPM_02374 6.7e-24 S Family of unknown function (DUF5325)
EHHHJOPM_02375 1.3e-36 ylaE
EHHHJOPM_02376 2.2e-13 sigC S Putative zinc-finger
EHHHJOPM_02377 5.3e-292 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
EHHHJOPM_02378 4e-83 ykzC S Acetyltransferase (GNAT) family
EHHHJOPM_02379 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
EHHHJOPM_02380 6.3e-24 ykzI
EHHHJOPM_02381 1.8e-118 yktB S Belongs to the UPF0637 family
EHHHJOPM_02382 3.5e-42 yktA S Belongs to the UPF0223 family
EHHHJOPM_02383 3.2e-275 speA 4.1.1.19 E Arginine
EHHHJOPM_02384 1e-134 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
EHHHJOPM_02385 1.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
EHHHJOPM_02386 5.4e-251 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHHHJOPM_02387 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHHHJOPM_02388 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHHHJOPM_02389 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHHHJOPM_02390 3.3e-208 V Beta-lactamase
EHHHJOPM_02391 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
EHHHJOPM_02392 0.0 Q Polyketide synthase of type I
EHHHJOPM_02393 0.0 Q Polyketide synthase of type I
EHHHJOPM_02394 0.0 Q Polyketide synthase of type I
EHHHJOPM_02395 0.0 Q Polyketide synthase of type I
EHHHJOPM_02396 0.0 Q polyketide synthase
EHHHJOPM_02397 0.0 Q Polyketide synthase of type I
EHHHJOPM_02398 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
EHHHJOPM_02399 4.2e-102 recN L Putative cell-wall binding lipoprotein
EHHHJOPM_02401 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EHHHJOPM_02402 7.4e-146 ykrA S hydrolases of the HAD superfamily
EHHHJOPM_02403 8.2e-31 ykzG S Belongs to the UPF0356 family
EHHHJOPM_02404 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EHHHJOPM_02405 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EHHHJOPM_02406 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
EHHHJOPM_02407 1e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
EHHHJOPM_02408 1.3e-243 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
EHHHJOPM_02409 2.1e-45 abrB K of stationary sporulation gene expression
EHHHJOPM_02410 6.9e-184 mreB D Rod-share determining protein MreBH
EHHHJOPM_02411 5.5e-12 S Uncharacterized protein YkpC
EHHHJOPM_02412 1.6e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EHHHJOPM_02413 3.4e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHHHJOPM_02414 4.2e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHHHJOPM_02415 1.7e-36 ykoA
EHHHJOPM_02416 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
EHHHJOPM_02417 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EHHHJOPM_02418 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
EHHHJOPM_02419 1.7e-131 fruR K Transcriptional regulator
EHHHJOPM_02420 3e-210 yknZ V ABC transporter (permease)
EHHHJOPM_02421 2e-121 macB V ABC transporter, ATP-binding protein
EHHHJOPM_02422 1.7e-167 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHHHJOPM_02423 3.4e-105 yknW S Yip1 domain
EHHHJOPM_02424 1.7e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EHHHJOPM_02425 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
EHHHJOPM_02426 4.2e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
EHHHJOPM_02427 1.4e-242 moeA 2.10.1.1 H molybdopterin
EHHHJOPM_02428 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EHHHJOPM_02429 1.8e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EHHHJOPM_02430 1.8e-160 yknT
EHHHJOPM_02431 4.5e-98 rok K Repressor of ComK
EHHHJOPM_02432 2.2e-76 ykuV CO thiol-disulfide
EHHHJOPM_02433 3.7e-140 ykuT M Mechanosensitive ion channel
EHHHJOPM_02434 4.8e-38 ykuS S Belongs to the UPF0180 family
EHHHJOPM_02435 9.9e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EHHHJOPM_02436 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EHHHJOPM_02437 6e-79 fld C Flavodoxin
EHHHJOPM_02438 2.2e-165 ykuO
EHHHJOPM_02439 1.3e-89 fld C Flavodoxin
EHHHJOPM_02440 1.3e-167 ccpC K Transcriptional regulator
EHHHJOPM_02441 1e-75 ykuL S CBS domain
EHHHJOPM_02442 2.1e-25 ykzF S Antirepressor AbbA
EHHHJOPM_02443 1.4e-92 ykuK S Ribonuclease H-like
EHHHJOPM_02444 3.9e-37 ykuJ S protein conserved in bacteria
EHHHJOPM_02445 3.3e-233 ykuI T Diguanylate phosphodiesterase
EHHHJOPM_02447 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHHJOPM_02448 3.1e-153 ykuE S Metallophosphoesterase
EHHHJOPM_02449 4.1e-89 ykuD S protein conserved in bacteria
EHHHJOPM_02450 2.5e-239 ykuC EGP Major facilitator Superfamily
EHHHJOPM_02451 1.4e-83 ykyB S YkyB-like protein
EHHHJOPM_02452 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
EHHHJOPM_02453 2.3e-09
EHHHJOPM_02454 3.9e-215 patA 2.6.1.1 E Aminotransferase
EHHHJOPM_02455 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
EHHHJOPM_02456 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
EHHHJOPM_02457 8.3e-113 ykwD J protein with SCP PR1 domains
EHHHJOPM_02458 2.8e-64
EHHHJOPM_02459 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EHHHJOPM_02460 6.5e-263 mcpC NT chemotaxis protein
EHHHJOPM_02461 2.4e-192 splB 4.1.99.14 L Spore photoproduct lyase
EHHHJOPM_02462 6.1e-38 splA S Transcriptional regulator
EHHHJOPM_02463 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHHHJOPM_02464 2.1e-39 ptsH G phosphocarrier protein HPr
EHHHJOPM_02465 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EHHHJOPM_02466 5.1e-156 glcT K antiterminator
EHHHJOPM_02467 3.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
EHHHJOPM_02469 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
EHHHJOPM_02470 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
EHHHJOPM_02471 1.7e-87 stoA CO thiol-disulfide
EHHHJOPM_02472 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHHJOPM_02473 9.1e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
EHHHJOPM_02474 3.9e-27
EHHHJOPM_02475 7.8e-25 ykvS S protein conserved in bacteria
EHHHJOPM_02476 2.9e-44 ykvR S Protein of unknown function (DUF3219)
EHHHJOPM_02477 3.8e-95 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHHHJOPM_02478 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EHHHJOPM_02479 3.8e-78 queD 4.1.2.50, 4.2.3.12 H synthase
EHHHJOPM_02480 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EHHHJOPM_02481 2.9e-183
EHHHJOPM_02482 5.1e-182 ykvI S membrane
EHHHJOPM_02483 0.0 clpE O Belongs to the ClpA ClpB family
EHHHJOPM_02484 3.3e-136 motA N flagellar motor
EHHHJOPM_02485 2.7e-127 motB N Flagellar motor protein
EHHHJOPM_02486 5.5e-77 ykvE K transcriptional
EHHHJOPM_02487 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
EHHHJOPM_02488 3.4e-10 S Spo0E like sporulation regulatory protein
EHHHJOPM_02489 7.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EHHHJOPM_02490 4.4e-112 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EHHHJOPM_02491 4.2e-129 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EHHHJOPM_02492 1.3e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EHHHJOPM_02493 2e-227 mtnE 2.6.1.83 E Aminotransferase
EHHHJOPM_02494 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EHHHJOPM_02495 2.1e-224 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EHHHJOPM_02496 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EHHHJOPM_02498 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHHHJOPM_02499 0.0 kinE 2.7.13.3 T Histidine kinase
EHHHJOPM_02500 8e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
EHHHJOPM_02501 8.7e-23 ykzE
EHHHJOPM_02502 7.2e-113 ydfR S Protein of unknown function (DUF421)
EHHHJOPM_02503 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
EHHHJOPM_02504 4.5e-155 htpX O Belongs to the peptidase M48B family
EHHHJOPM_02505 8.6e-125 ykrK S Domain of unknown function (DUF1836)
EHHHJOPM_02506 2.5e-26 sspD S small acid-soluble spore protein
EHHHJOPM_02507 1.5e-118 rsgI S Anti-sigma factor N-terminus
EHHHJOPM_02508 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHHJOPM_02509 3.3e-133 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EHHHJOPM_02510 3.8e-99 ykoX S membrane-associated protein
EHHHJOPM_02511 7.9e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EHHHJOPM_02512 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
EHHHJOPM_02513 3.7e-99 ykoP G polysaccharide deacetylase
EHHHJOPM_02514 1.1e-80 ykoM K transcriptional
EHHHJOPM_02515 1.2e-25 ykoL
EHHHJOPM_02516 1.9e-16
EHHHJOPM_02517 5.4e-53 tnrA K transcriptional
EHHHJOPM_02518 3.2e-237 mgtE P Acts as a magnesium transporter
EHHHJOPM_02520 7.4e-244 ydhD M Glycosyl hydrolase
EHHHJOPM_02521 3.8e-97 ykoE S ABC-type cobalt transport system, permease component
EHHHJOPM_02522 5.3e-303 P ABC transporter, ATP-binding protein
EHHHJOPM_02523 2.1e-132 ykoC P Cobalt transport protein
EHHHJOPM_02524 4.3e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHHHJOPM_02525 5e-176 isp O Belongs to the peptidase S8 family
EHHHJOPM_02526 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHHHJOPM_02527 8.9e-122 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EHHHJOPM_02528 3e-215 hcaT 1.5.1.2 EGP Major facilitator Superfamily
EHHHJOPM_02529 8.2e-120 M PFAM Collagen triple helix repeat (20 copies)
EHHHJOPM_02530 1.1e-214 M Glycosyl transferase family 2
EHHHJOPM_02532 4.1e-48 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EHHHJOPM_02533 4.2e-71 ohrB O Organic hydroperoxide resistance protein
EHHHJOPM_02534 1.8e-72 ohrR K COG1846 Transcriptional regulators
EHHHJOPM_02535 4.1e-69 ohrA O Organic hydroperoxide resistance protein
EHHHJOPM_02536 2.2e-224 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHHHJOPM_02537 6.6e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHHHJOPM_02538 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EHHHJOPM_02539 1e-48 ykkD P Multidrug resistance protein
EHHHJOPM_02540 1.4e-51 ykkC P Multidrug resistance protein
EHHHJOPM_02541 1.1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EHHHJOPM_02542 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
EHHHJOPM_02543 1.5e-158 ykgA E Amidinotransferase
EHHHJOPM_02544 1.3e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
EHHHJOPM_02545 1.6e-182 ykfD E Belongs to the ABC transporter superfamily
EHHHJOPM_02546 1.1e-167 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EHHHJOPM_02547 3.1e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
EHHHJOPM_02548 7.5e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EHHHJOPM_02549 0.0 dppE E ABC transporter substrate-binding protein
EHHHJOPM_02550 5.9e-191 dppD P Belongs to the ABC transporter superfamily
EHHHJOPM_02551 2.5e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHHJOPM_02552 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHHJOPM_02553 1.9e-155 dppA E D-aminopeptidase
EHHHJOPM_02554 3.7e-277 yubD P Major Facilitator Superfamily
EHHHJOPM_02555 5.6e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHHHJOPM_02557 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EHHHJOPM_02558 4.2e-300 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHHHJOPM_02559 8.2e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
EHHHJOPM_02560 1.1e-242 steT E amino acid
EHHHJOPM_02561 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
EHHHJOPM_02562 5.8e-175 pit P phosphate transporter
EHHHJOPM_02563 5.9e-132 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
EHHHJOPM_02564 8.7e-23 spoIISB S Stage II sporulation protein SB
EHHHJOPM_02565 5.4e-169 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EHHHJOPM_02566 1.3e-38 xhlB S SPP1 phage holin
EHHHJOPM_02567 8.7e-38 xhlA S Haemolysin XhlA
EHHHJOPM_02568 5.3e-136 xepA
EHHHJOPM_02569 1.6e-28 xkdX
EHHHJOPM_02571 1.7e-91
EHHHJOPM_02572 3.6e-26
EHHHJOPM_02573 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
EHHHJOPM_02574 1.5e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EHHHJOPM_02575 4.2e-58 xkdS S Protein of unknown function (DUF2634)
EHHHJOPM_02576 2.5e-32 xkdR S Protein of unknown function (DUF2577)
EHHHJOPM_02577 4.6e-161 xkdQ 3.2.1.96 G NLP P60 protein
EHHHJOPM_02578 6.6e-111 xkdP S Lysin motif
EHHHJOPM_02579 3.4e-199 xkdO L Transglycosylase SLT domain
EHHHJOPM_02580 3.4e-19
EHHHJOPM_02581 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
EHHHJOPM_02582 2e-74 xkdM S Phage tail tube protein
EHHHJOPM_02583 3.5e-226 xkdK S Phage tail sheath C-terminal domain
EHHHJOPM_02584 8.2e-15
EHHHJOPM_02585 3.2e-56 xkdJ
EHHHJOPM_02586 5.3e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
EHHHJOPM_02587 5.5e-43 yqbH S Domain of unknown function (DUF3599)
EHHHJOPM_02588 4.3e-46 yqbG S Protein of unknown function (DUF3199)
EHHHJOPM_02589 1e-157 xkdG S Phage capsid family
EHHHJOPM_02590 1.3e-90 xkdF 2.1.1.72 L Putative phage serine protease XkdF
EHHHJOPM_02591 3e-241 yqbA S portal protein
EHHHJOPM_02592 1.4e-210 xtmB S phage terminase, large subunit
EHHHJOPM_02593 3e-110 xtmA L phage terminase small subunit
EHHHJOPM_02594 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EHHHJOPM_02595 2e-10 yqaO S Phage-like element PBSX protein XtrA
EHHHJOPM_02598 5.2e-150 xkdC L Bacterial dnaA protein
EHHHJOPM_02600 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
EHHHJOPM_02601 2.9e-110 xkdA E IrrE N-terminal-like domain
EHHHJOPM_02603 6.7e-110 yjqB S phage-related replication protein
EHHHJOPM_02604 8e-61 yjqA S Bacterial PH domain
EHHHJOPM_02605 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EHHHJOPM_02607 4.9e-215 S response regulator aspartate phosphatase
EHHHJOPM_02608 3.1e-78 yjoA S DinB family
EHHHJOPM_02609 1.9e-130 MA20_18170 S membrane transporter protein
EHHHJOPM_02610 3.4e-204 salB V Domain of unknown function (DUF4135)
EHHHJOPM_02613 3.7e-219 lanT 3.6.3.27 V Peptidase C39 family
EHHHJOPM_02614 4.8e-300 lcnDR2 V Lanthionine synthetase C-like protein
EHHHJOPM_02616 5.4e-60 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHHJOPM_02617 6e-36 narQ 2.7.13.3 T Histidine kinase
EHHHJOPM_02619 2.7e-65 S ABC-2 family transporter protein
EHHHJOPM_02620 3.8e-104 V ABC transporter, ATP-binding protein
EHHHJOPM_02621 1.4e-131 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EHHHJOPM_02622 4e-87 T Transcriptional regulatory protein, C terminal
EHHHJOPM_02623 1.3e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
EHHHJOPM_02624 1.9e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
EHHHJOPM_02625 7e-181 exuR K transcriptional
EHHHJOPM_02626 3.3e-253 yjmB G symporter YjmB
EHHHJOPM_02627 4e-275 uxaC 5.3.1.12 G glucuronate isomerase
EHHHJOPM_02628 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
EHHHJOPM_02629 7e-66 yjlC S Protein of unknown function (DUF1641)
EHHHJOPM_02630 5.7e-91 yjlB S Cupin domain
EHHHJOPM_02631 4.4e-175 yjlA EG Putative multidrug resistance efflux transporter
EHHHJOPM_02632 1.6e-129 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
EHHHJOPM_02633 2.1e-124 ybbM S transport system, permease component
EHHHJOPM_02634 4.7e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
EHHHJOPM_02635 6.8e-29
EHHHJOPM_02636 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EHHHJOPM_02637 4.8e-224 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
EHHHJOPM_02638 4.3e-92 yjgD S Protein of unknown function (DUF1641)
EHHHJOPM_02639 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
EHHHJOPM_02640 5.9e-100 yjgB S Domain of unknown function (DUF4309)
EHHHJOPM_02641 2.6e-65 T PhoQ Sensor
EHHHJOPM_02642 7.5e-22 yjfB S Putative motility protein
EHHHJOPM_02644 8.1e-106 yhiD S MgtC SapB transporter
EHHHJOPM_02645 2.9e-51 K helix_turn_helix multiple antibiotic resistance protein
EHHHJOPM_02646 2e-34
EHHHJOPM_02647 2.1e-123 5.4.2.6 S Haloacid dehalogenase-like hydrolase
EHHHJOPM_02648 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
EHHHJOPM_02649 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
EHHHJOPM_02650 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
EHHHJOPM_02651 2.9e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EHHHJOPM_02652 4.3e-214 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHHHJOPM_02653 1.8e-184 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EHHHJOPM_02654 9.9e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
EHHHJOPM_02655 3.8e-220 ganA 3.2.1.89 G arabinogalactan
EHHHJOPM_02656 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
EHHHJOPM_02657 3.5e-250 yfjF EGP Belongs to the major facilitator superfamily
EHHHJOPM_02658 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
EHHHJOPM_02659 1.3e-160 bla 3.5.2.6 V beta-lactamase
EHHHJOPM_02660 8.5e-58 E Glyoxalase-like domain
EHHHJOPM_02663 4.9e-305 yobL S Bacterial EndoU nuclease
EHHHJOPM_02664 2.6e-21
EHHHJOPM_02668 2.4e-62
EHHHJOPM_02670 5.7e-119 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
EHHHJOPM_02671 9e-61 S Pfam:Phage_holin_4_1
EHHHJOPM_02676 4.2e-225 S peptidoglycan catabolic process
EHHHJOPM_02677 7.3e-45
EHHHJOPM_02678 2e-124
EHHHJOPM_02680 1.9e-25 S Phage tail assembly chaperone protein, TAC
EHHHJOPM_02681 4.3e-33 S Phage tail tube protein
EHHHJOPM_02682 7.7e-30 S Protein of unknown function (DUF3168)
EHHHJOPM_02683 3.6e-38 S Bacteriophage HK97-gp10, putative tail-component
EHHHJOPM_02684 3.6e-28 S Phage head-tail joining protein
EHHHJOPM_02685 6e-27 S Phage gp6-like head-tail connector protein
EHHHJOPM_02688 2e-145 S Phage capsid family
EHHHJOPM_02689 4e-59 S Domain of unknown function (DUF4355)
EHHHJOPM_02690 4.3e-92 S Phage Mu protein F like protein
EHHHJOPM_02691 7.8e-202 S Phage portal protein, SPP1 Gp6-like
EHHHJOPM_02692 2.5e-180 ps334 S Terminase-like family
EHHHJOPM_02693 4.5e-79 yqaS L DNA packaging
EHHHJOPM_02695 8.5e-66 O Papain family cysteine protease
EHHHJOPM_02696 7.9e-13 K Transcriptional regulator
EHHHJOPM_02698 5.4e-68 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EHHHJOPM_02702 1.2e-125 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
EHHHJOPM_02705 5e-17 yqaO S Phage-like element PBSX protein XtrA
EHHHJOPM_02707 5.9e-60 rusA L Endodeoxyribonuclease RusA
EHHHJOPM_02709 5.5e-122 xkdC L IstB-like ATP binding protein
EHHHJOPM_02710 1.4e-74 3.1.3.16 L DnaD domain protein
EHHHJOPM_02712 1.3e-68 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
EHHHJOPM_02713 4.3e-100
EHHHJOPM_02718 3.2e-85
EHHHJOPM_02719 6.3e-46 S Phage regulatory protein Rha (Phage_pRha)
EHHHJOPM_02720 3.4e-15 S Helix-turn-helix domain
EHHHJOPM_02721 4.2e-17 K Helix-turn-helix domain
EHHHJOPM_02722 3.7e-18 xre K Helix-turn-helix XRE-family like proteins
EHHHJOPM_02723 5.7e-26 S Short C-terminal domain
EHHHJOPM_02724 1.3e-48 xkdA E IrrE N-terminal-like domain
EHHHJOPM_02725 8.4e-176 L Belongs to the 'phage' integrase family
EHHHJOPM_02727 2.2e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EHHHJOPM_02728 4.3e-211 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EHHHJOPM_02729 3e-125 yjcH P COG2382 Enterochelin esterase and related enzymes
EHHHJOPM_02730 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
EHHHJOPM_02731 2.3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHHHJOPM_02732 2.7e-35 K SpoVT / AbrB like domain
EHHHJOPM_02733 6.4e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
EHHHJOPM_02734 5.7e-124 S ABC-2 type transporter
EHHHJOPM_02735 2.2e-139 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
EHHHJOPM_02736 1.3e-35
EHHHJOPM_02737 0.0 yjcD 3.6.4.12 L DNA helicase
EHHHJOPM_02738 3.8e-38 spoVIF S Stage VI sporulation protein F
EHHHJOPM_02742 5.6e-56 yjcA S Protein of unknown function (DUF1360)
EHHHJOPM_02743 1.4e-52 cotV S Spore Coat Protein X and V domain
EHHHJOPM_02744 6.8e-21 cotW
EHHHJOPM_02745 5.1e-71 cotX S Spore Coat Protein X and V domain
EHHHJOPM_02746 4.6e-93 cotY S Spore coat protein Z
EHHHJOPM_02747 6.7e-83 cotZ S Spore coat protein
EHHHJOPM_02748 2.1e-84 yjbX S Spore coat protein
EHHHJOPM_02749 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
EHHHJOPM_02750 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EHHHJOPM_02751 2.1e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EHHHJOPM_02752 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EHHHJOPM_02753 6.7e-30 thiS H Thiamine biosynthesis
EHHHJOPM_02754 8e-210 thiO 1.4.3.19 E Glycine oxidase
EHHHJOPM_02755 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
EHHHJOPM_02756 6.4e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHHHJOPM_02757 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EHHHJOPM_02758 2.6e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EHHHJOPM_02759 3.7e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EHHHJOPM_02760 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHHHJOPM_02761 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
EHHHJOPM_02762 3.9e-60 yjbL S Belongs to the UPF0738 family
EHHHJOPM_02763 4e-96 yjbK S protein conserved in bacteria
EHHHJOPM_02764 1.2e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EHHHJOPM_02765 4.8e-72 yjbI S Bacterial-like globin
EHHHJOPM_02766 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
EHHHJOPM_02767 5.8e-19
EHHHJOPM_02768 0.0 pepF E oligoendopeptidase F
EHHHJOPM_02769 1.4e-217 yjbF S Competence protein
EHHHJOPM_02770 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EHHHJOPM_02771 4.7e-109 yjbE P Integral membrane protein TerC family
EHHHJOPM_02772 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EHHHJOPM_02773 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHHHJOPM_02774 9.8e-230 S Putative glycosyl hydrolase domain
EHHHJOPM_02775 2.3e-170 oppF E Belongs to the ABC transporter superfamily
EHHHJOPM_02776 2.7e-202 oppD P Belongs to the ABC transporter superfamily
EHHHJOPM_02777 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHHJOPM_02778 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHHJOPM_02779 0.0 oppA E ABC transporter substrate-binding protein
EHHHJOPM_02780 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EHHHJOPM_02781 1.2e-145 yjbA S Belongs to the UPF0736 family
EHHHJOPM_02782 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHHJOPM_02783 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHHJOPM_02784 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
EHHHJOPM_02785 5.9e-188 appF E Belongs to the ABC transporter superfamily
EHHHJOPM_02786 1.7e-182 appD P Belongs to the ABC transporter superfamily
EHHHJOPM_02787 5.6e-149 yjaZ O Zn-dependent protease
EHHHJOPM_02788 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHHHJOPM_02789 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHHHJOPM_02790 1e-31 yjzB
EHHHJOPM_02791 1.1e-26 comZ S ComZ
EHHHJOPM_02792 2.7e-165 med S Transcriptional activator protein med
EHHHJOPM_02793 8.8e-104 yjaV
EHHHJOPM_02794 4.6e-137 yjaU I carboxylic ester hydrolase activity
EHHHJOPM_02795 3.3e-23 yjzD S Protein of unknown function (DUF2929)
EHHHJOPM_02796 1.2e-27 yjzC S YjzC-like protein
EHHHJOPM_02797 7.8e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHHHJOPM_02798 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
EHHHJOPM_02799 1.3e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
EHHHJOPM_02800 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EHHHJOPM_02801 1.6e-135 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
EHHHJOPM_02802 6.1e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EHHHJOPM_02803 5.6e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHHHJOPM_02804 1.2e-89 norB G Major Facilitator Superfamily
EHHHJOPM_02805 1.5e-272 yitY C D-arabinono-1,4-lactone oxidase
EHHHJOPM_02806 4.6e-73 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EHHHJOPM_02807 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
EHHHJOPM_02808 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
EHHHJOPM_02809 4.3e-152 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EHHHJOPM_02810 3.5e-07
EHHHJOPM_02811 4.4e-26 S Protein of unknown function (DUF3813)
EHHHJOPM_02812 9.6e-23 ipi S Intracellular proteinase inhibitor
EHHHJOPM_02813 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
EHHHJOPM_02814 4.6e-157 yitS S protein conserved in bacteria
EHHHJOPM_02816 1.7e-232 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
EHHHJOPM_02817 2.2e-171 yufN S ABC transporter substrate-binding protein PnrA-like
EHHHJOPM_02818 7.6e-160 cvfB S protein conserved in bacteria
EHHHJOPM_02819 6.6e-55 yajQ S Belongs to the UPF0234 family
EHHHJOPM_02820 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EHHHJOPM_02821 2.4e-80 yjcF S Acetyltransferase (GNAT) domain
EHHHJOPM_02822 1.6e-69 mcbG S Pentapeptide repeats (9 copies)
EHHHJOPM_02823 9.8e-83 yisT S DinB family
EHHHJOPM_02824 7.6e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
EHHHJOPM_02825 4.1e-144 purR K helix_turn _helix lactose operon repressor
EHHHJOPM_02826 2.3e-159 yisR K Transcriptional regulator
EHHHJOPM_02827 1.5e-245 yisQ V Mate efflux family protein
EHHHJOPM_02828 2.2e-131 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
EHHHJOPM_02829 0.0 asnO 6.3.5.4 E Asparagine synthase
EHHHJOPM_02830 7.6e-97 yisN S Protein of unknown function (DUF2777)
EHHHJOPM_02831 3.2e-59 yisL S UPF0344 protein
EHHHJOPM_02832 5.1e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EHHHJOPM_02833 4.8e-07 yisI S Spo0E like sporulation regulatory protein
EHHHJOPM_02834 8.4e-34 gerPA S Spore germination protein
EHHHJOPM_02835 1.8e-34 gerPB S cell differentiation
EHHHJOPM_02836 1.4e-62 gerPC S Spore germination protein
EHHHJOPM_02837 3.1e-23 gerPD S Spore germination protein
EHHHJOPM_02838 1.1e-63 gerPE S Spore germination protein GerPE
EHHHJOPM_02839 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
EHHHJOPM_02840 5e-50 yisB V COG1403 Restriction endonuclease
EHHHJOPM_02841 0.0 sbcC L COG0419 ATPase involved in DNA repair
EHHHJOPM_02842 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EHHHJOPM_02843 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EHHHJOPM_02844 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
EHHHJOPM_02845 2.5e-119 ydfS S Protein of unknown function (DUF421)
EHHHJOPM_02846 6.3e-93 yhjR S Rubrerythrin
EHHHJOPM_02847 1.1e-107 K QacR-like protein, C-terminal region
EHHHJOPM_02848 3e-202 blt EGP Major facilitator Superfamily
EHHHJOPM_02849 1.8e-188 abrB S membrane
EHHHJOPM_02850 8.4e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
EHHHJOPM_02851 1.6e-269 yhjG CH FAD binding domain
EHHHJOPM_02853 6e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
EHHHJOPM_02854 2.6e-109 yhjE S SNARE associated Golgi protein
EHHHJOPM_02855 1.7e-60 yhjD
EHHHJOPM_02856 3.1e-27 yhjC S Protein of unknown function (DUF3311)
EHHHJOPM_02857 3.8e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHHHJOPM_02858 3.3e-47 S Belongs to the UPF0145 family
EHHHJOPM_02859 1.6e-42 yhjA S Excalibur calcium-binding domain
EHHHJOPM_02860 8.7e-125 yrpD S Domain of unknown function, YrpD
EHHHJOPM_02861 3.5e-61 frataxin S Domain of unknown function (DU1801)
EHHHJOPM_02862 4.7e-66 frataxin S Domain of unknown function (DU1801)
EHHHJOPM_02863 1.9e-109 comK K Competence transcription factor
EHHHJOPM_02864 5.4e-31 yhzC S IDEAL
EHHHJOPM_02865 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHHJOPM_02866 1.3e-295 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
EHHHJOPM_02867 1.5e-196 hemAT NT chemotaxis protein
EHHHJOPM_02868 3.5e-89 bioY S BioY family
EHHHJOPM_02869 3.6e-279 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EHHHJOPM_02870 6.7e-201 vraB 2.3.1.9 I Belongs to the thiolase family
EHHHJOPM_02871 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
EHHHJOPM_02872 1.6e-149 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EHHHJOPM_02873 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
EHHHJOPM_02874 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
EHHHJOPM_02875 1.3e-64 yhfM
EHHHJOPM_02876 2.7e-296 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
EHHHJOPM_02877 7.9e-109 yhfK GM NmrA-like family
EHHHJOPM_02878 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
EHHHJOPM_02879 2.2e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EHHHJOPM_02880 7.9e-11 yhfH S YhfH-like protein
EHHHJOPM_02881 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHHHJOPM_02882 1.7e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
EHHHJOPM_02884 3.7e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHHHJOPM_02885 7.2e-245 yhgE S YhgE Pip N-terminal domain protein
EHHHJOPM_02886 3.2e-101 yhgD K Transcriptional regulator
EHHHJOPM_02888 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EHHHJOPM_02889 9.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EHHHJOPM_02890 3.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHHHJOPM_02891 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EHHHJOPM_02892 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
EHHHJOPM_02893 6.2e-244 yhfA C membrane
EHHHJOPM_02894 7.5e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EHHHJOPM_02895 4e-122 ecsC S EcsC protein family
EHHHJOPM_02896 1.5e-220 ecsB U ABC transporter
EHHHJOPM_02897 1.1e-135 ecsA V transporter (ATP-binding protein)
EHHHJOPM_02898 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EHHHJOPM_02899 2.3e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHHHJOPM_02900 1.4e-76 trpP S Tryptophan transporter TrpP
EHHHJOPM_02901 2e-17
EHHHJOPM_02902 6.2e-39 yhaH S YtxH-like protein
EHHHJOPM_02903 8.6e-113 hpr K Negative regulator of protease production and sporulation
EHHHJOPM_02904 1.7e-54 yhaI S Protein of unknown function (DUF1878)
EHHHJOPM_02905 7e-95 yhaK S Putative zincin peptidase
EHHHJOPM_02906 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EHHHJOPM_02907 1.8e-31 yhaL S Sporulation protein YhaL
EHHHJOPM_02908 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
EHHHJOPM_02909 0.0 yhaN L AAA domain
EHHHJOPM_02910 7.2e-236 yhaO L DNA repair exonuclease
EHHHJOPM_02911 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
EHHHJOPM_02912 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
EHHHJOPM_02913 2.8e-14 S YhzD-like protein
EHHHJOPM_02914 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
EHHHJOPM_02916 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
EHHHJOPM_02917 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
EHHHJOPM_02918 4.6e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
EHHHJOPM_02919 3.3e-291 hemZ H coproporphyrinogen III oxidase
EHHHJOPM_02920 2.8e-157 yhaX S haloacid dehalogenase-like hydrolase
EHHHJOPM_02921 3.5e-200 yhaZ L DNA alkylation repair enzyme
EHHHJOPM_02922 4.4e-53 yheA S Belongs to the UPF0342 family
EHHHJOPM_02923 1e-204 yheB S Belongs to the UPF0754 family
EHHHJOPM_02924 3.4e-213 yheC HJ YheC/D like ATP-grasp
EHHHJOPM_02925 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
EHHHJOPM_02926 1.7e-36 yheE S Family of unknown function (DUF5342)
EHHHJOPM_02927 1.3e-28 sspB S spore protein
EHHHJOPM_02929 1.6e-111 yheG GM NAD(P)H-binding
EHHHJOPM_02930 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
EHHHJOPM_02931 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
EHHHJOPM_02933 6.2e-85 T universal stress protein
EHHHJOPM_02934 1.8e-93 ymcC S Membrane
EHHHJOPM_02935 3e-87 pksA K Transcriptional regulator
EHHHJOPM_02936 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EHHHJOPM_02937 1.1e-155 yheN G deacetylase
EHHHJOPM_02938 2.9e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EHHHJOPM_02939 3.5e-205 yhdY M Mechanosensitive ion channel
EHHHJOPM_02941 7.2e-127 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EHHHJOPM_02942 1.9e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHHHJOPM_02943 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHHHJOPM_02944 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
EHHHJOPM_02945 1.6e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHHHJOPM_02946 3.6e-224 yhdR 2.6.1.1 E Aminotransferase
EHHHJOPM_02947 2.8e-70 cueR K transcriptional
EHHHJOPM_02948 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
EHHHJOPM_02949 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EHHHJOPM_02950 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
EHHHJOPM_02951 1.3e-201 yhdL S Sigma factor regulator N-terminal
EHHHJOPM_02952 8.1e-45 yhdK S Sigma-M inhibitor protein
EHHHJOPM_02953 2.9e-198 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EHHHJOPM_02954 1.2e-250 yhdG E amino acid
EHHHJOPM_02955 8.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHHJOPM_02956 1.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
EHHHJOPM_02957 1.3e-162 citR K Transcriptional regulator
EHHHJOPM_02958 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EHHHJOPM_02959 7.5e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
EHHHJOPM_02960 3e-270 ycgB S Stage V sporulation protein R
EHHHJOPM_02961 3.1e-244 ygxB M Conserved TM helix
EHHHJOPM_02962 1.6e-73 nsrR K Transcriptional regulator
EHHHJOPM_02963 5.4e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
EHHHJOPM_02964 1.1e-53 yhdC S Protein of unknown function (DUF3889)
EHHHJOPM_02965 2.5e-39 yhdB S YhdB-like protein
EHHHJOPM_02966 4.3e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
EHHHJOPM_02967 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHHJOPM_02968 1.3e-202 yhcY 2.7.13.3 T Histidine kinase
EHHHJOPM_02969 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EHHHJOPM_02970 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHHHJOPM_02971 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHHHJOPM_02972 3.2e-147 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
EHHHJOPM_02973 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EHHHJOPM_02974 7.8e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHHHJOPM_02975 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EHHHJOPM_02976 4.9e-125 yhcW 5.4.2.6 S hydrolase
EHHHJOPM_02977 9.9e-68 yhcV S COG0517 FOG CBS domain
EHHHJOPM_02978 1.3e-69 yhcU S Family of unknown function (DUF5365)
EHHHJOPM_02979 2.6e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EHHHJOPM_02980 1.7e-105 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
EHHHJOPM_02981 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
EHHHJOPM_02982 8.4e-114 yhcQ M Spore coat protein
EHHHJOPM_02983 2.2e-160 yhcP
EHHHJOPM_02984 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EHHHJOPM_02985 1.9e-51 yhcM
EHHHJOPM_02986 9.7e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHHHJOPM_02987 2.5e-184 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
EHHHJOPM_02988 1.8e-142 metQ M Belongs to the nlpA lipoprotein family
EHHHJOPM_02989 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
EHHHJOPM_02990 8.2e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EHHHJOPM_02991 1.3e-165 yhcH V ABC transporter, ATP-binding protein
EHHHJOPM_02992 2.8e-123 yhcG V ABC transporter, ATP-binding protein
EHHHJOPM_02993 3.6e-61 yhcF K Transcriptional regulator
EHHHJOPM_02994 4.8e-52
EHHHJOPM_02995 3.8e-55 yhcC
EHHHJOPM_02996 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
EHHHJOPM_02997 8.4e-285 yhcA EGP Major facilitator Superfamily
EHHHJOPM_02998 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
EHHHJOPM_02999 5e-73 yhbI K DNA-binding transcription factor activity
EHHHJOPM_03000 3.9e-215 yhbH S Belongs to the UPF0229 family
EHHHJOPM_03001 0.0 prkA T Ser protein kinase
EHHHJOPM_03003 5.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
EHHHJOPM_03004 5.2e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
EHHHJOPM_03005 2.8e-106 yhbD K Protein of unknown function (DUF4004)
EHHHJOPM_03006 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EHHHJOPM_03007 1.4e-173 yhbB S Putative amidase domain
EHHHJOPM_03008 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHHHJOPM_03009 7.2e-107 yhzB S B3/4 domain
EHHHJOPM_03011 4.8e-23 K Transcriptional regulator
EHHHJOPM_03012 3.3e-80 ygaO
EHHHJOPM_03013 2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHHHJOPM_03014 1.4e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
EHHHJOPM_03015 7.5e-144 ssuC P ABC transporter (permease)
EHHHJOPM_03016 1.7e-179 ssuA M Sulfonate ABC transporter
EHHHJOPM_03017 6.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EHHHJOPM_03018 2.5e-180 S Amidohydrolase
EHHHJOPM_03019 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
EHHHJOPM_03020 2.4e-133 oppF3 E Belongs to the ABC transporter superfamily
EHHHJOPM_03021 3.7e-134 oppD3 P Belongs to the ABC transporter superfamily
EHHHJOPM_03022 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHHHJOPM_03023 3.7e-147 appB P Binding-protein-dependent transport system inner membrane component
EHHHJOPM_03024 3.7e-230 oppA5 E PFAM extracellular solute-binding protein family 5
EHHHJOPM_03026 2.6e-264 ygaK C Berberine and berberine like
EHHHJOPM_03027 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHHHJOPM_03028 1.4e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
EHHHJOPM_03029 6.8e-40 C Na+/H+ antiporter family
EHHHJOPM_03033 1.6e-08
EHHHJOPM_03041 7.8e-08
EHHHJOPM_03046 3.4e-39 S COG NOG14552 non supervised orthologous group
EHHHJOPM_03047 1.1e-164 ygxA S Nucleotidyltransferase-like
EHHHJOPM_03048 1.5e-56 ygzB S UPF0295 protein
EHHHJOPM_03049 1.8e-80 perR P Belongs to the Fur family
EHHHJOPM_03050 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
EHHHJOPM_03051 2.3e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
EHHHJOPM_03052 2.7e-178 ygaE S Membrane
EHHHJOPM_03053 9.1e-301 ygaD V ABC transporter
EHHHJOPM_03054 2.2e-104 ygaC J Belongs to the UPF0374 family
EHHHJOPM_03055 1.5e-37 ygaB S YgaB-like protein
EHHHJOPM_03057 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHHJOPM_03058 3.1e-36 yfhS
EHHHJOPM_03059 4.8e-207 mutY L A G-specific
EHHHJOPM_03060 1e-184 yfhP S membrane-bound metal-dependent
EHHHJOPM_03061 0.0 yfhO S Bacterial membrane protein YfhO
EHHHJOPM_03062 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EHHHJOPM_03063 3.1e-169 yfhM S Alpha/beta hydrolase family
EHHHJOPM_03064 4.8e-33 yfhL S SdpI/YhfL protein family
EHHHJOPM_03065 2.2e-93 batE T Bacterial SH3 domain homologues
EHHHJOPM_03066 2.2e-44 yfhJ S WVELL protein
EHHHJOPM_03067 5.3e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
EHHHJOPM_03069 1.1e-204 yfhI EGP Major facilitator Superfamily
EHHHJOPM_03070 2.5e-52 yfhH S Protein of unknown function (DUF1811)
EHHHJOPM_03071 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
EHHHJOPM_03072 2.2e-165 yfhF S nucleoside-diphosphate sugar epimerase
EHHHJOPM_03074 2.1e-25 yfhD S YfhD-like protein
EHHHJOPM_03075 1.7e-105 yfhC C nitroreductase
EHHHJOPM_03076 7.2e-161 yfhB 5.3.3.17 S PhzF family
EHHHJOPM_03077 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EHHHJOPM_03078 6.2e-82 yfiV K transcriptional
EHHHJOPM_03079 1.1e-289 yfiU EGP Major facilitator Superfamily
EHHHJOPM_03080 2.9e-96 yfiT S Belongs to the metal hydrolase YfiT family
EHHHJOPM_03081 4.5e-45 yrdF K ribonuclease inhibitor
EHHHJOPM_03082 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
EHHHJOPM_03083 1.9e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EHHHJOPM_03084 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
EHHHJOPM_03085 1.9e-95 padR K transcriptional
EHHHJOPM_03086 1.1e-164 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EHHHJOPM_03087 1.1e-158 yfiE 1.13.11.2 S glyoxalase
EHHHJOPM_03088 2e-62 mhqP S DoxX
EHHHJOPM_03089 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
EHHHJOPM_03090 1.2e-308 yfiB3 V ABC transporter
EHHHJOPM_03091 8.3e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EHHHJOPM_03092 1.7e-139 glvR F Helix-turn-helix domain, rpiR family
EHHHJOPM_03093 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EHHHJOPM_03094 4.2e-15 sspH S Belongs to the SspH family
EHHHJOPM_03095 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
EHHHJOPM_03096 2.3e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EHHHJOPM_03097 7.1e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EHHHJOPM_03098 8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EHHHJOPM_03099 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EHHHJOPM_03100 3.7e-87 yfjM S Psort location Cytoplasmic, score
EHHHJOPM_03101 3.5e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHHHJOPM_03102 1.5e-43 S YfzA-like protein
EHHHJOPM_03103 8.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHHHJOPM_03104 2.8e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHHHJOPM_03105 8.5e-184 corA P Mediates influx of magnesium ions
EHHHJOPM_03106 3.3e-30
EHHHJOPM_03107 6.8e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EHHHJOPM_03108 9e-155 pdaA G deacetylase
EHHHJOPM_03109 4.9e-27 yfjT
EHHHJOPM_03110 7.3e-219 yfkA S YfkB-like domain
EHHHJOPM_03111 1e-145 yfkC M Mechanosensitive ion channel
EHHHJOPM_03112 1e-142 yfkD S YfkD-like protein
EHHHJOPM_03113 5.5e-184 cax P COG0387 Ca2 H antiporter
EHHHJOPM_03114 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
EHHHJOPM_03115 2.5e-07
EHHHJOPM_03116 7.6e-144 yihY S Belongs to the UPF0761 family
EHHHJOPM_03117 1.7e-51 yfkI S gas vesicle protein
EHHHJOPM_03118 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHHHJOPM_03119 2.7e-29 yfkK S Belongs to the UPF0435 family
EHHHJOPM_03120 3.6e-192 ydiM EGP Major facilitator Superfamily
EHHHJOPM_03121 3.4e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EHHHJOPM_03122 4.3e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHHHJOPM_03123 6.4e-185 K helix_turn _helix lactose operon repressor
EHHHJOPM_03124 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
EHHHJOPM_03125 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
EHHHJOPM_03126 5.5e-198 yibE S YibE/F-like protein
EHHHJOPM_03127 1e-123 yibF S YibE/F-like protein
EHHHJOPM_03128 1.2e-123 yfkO C nitroreductase
EHHHJOPM_03129 2e-129 treR K transcriptional
EHHHJOPM_03130 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EHHHJOPM_03131 9.5e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EHHHJOPM_03132 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
EHHHJOPM_03133 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
EHHHJOPM_03134 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
EHHHJOPM_03135 2.5e-62 yhdN S Domain of unknown function (DUF1992)
EHHHJOPM_03136 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EHHHJOPM_03137 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
EHHHJOPM_03138 2.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EHHHJOPM_03139 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
EHHHJOPM_03140 3.1e-50 yflH S Protein of unknown function (DUF3243)
EHHHJOPM_03141 7e-19 yflI
EHHHJOPM_03142 1.5e-14 yflJ S Protein of unknown function (DUF2639)
EHHHJOPM_03143 1.3e-122 yflK S protein conserved in bacteria
EHHHJOPM_03144 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EHHHJOPM_03145 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EHHHJOPM_03146 4.8e-148 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
EHHHJOPM_03147 3.6e-225 citM C Citrate transporter
EHHHJOPM_03148 1.7e-176 yflP S Tripartite tricarboxylate transporter family receptor
EHHHJOPM_03149 2.6e-118 citT T response regulator
EHHHJOPM_03150 6.2e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EHHHJOPM_03151 3.5e-80 srtA 3.4.22.70 M Sortase family
EHHHJOPM_03152 0.0 M1-568 M cell wall anchor domain
EHHHJOPM_03153 1.3e-151 M1-574 T Transcriptional regulatory protein, C terminal
EHHHJOPM_03154 0.0 ywpD T PhoQ Sensor
EHHHJOPM_03155 6.8e-24 M1-820 Q Collagen triple helix repeat (20 copies)
EHHHJOPM_03156 3.3e-23 M1-820 Q Collagen triple helix repeat (20 copies)
EHHHJOPM_03158 5.2e-27 Q PFAM Collagen triple helix
EHHHJOPM_03159 6e-234 yflS P Sodium:sulfate symporter transmembrane region
EHHHJOPM_03160 1.7e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
EHHHJOPM_03161 1.3e-57 yflT S Heat induced stress protein YflT
EHHHJOPM_03162 2.7e-24 S Protein of unknown function (DUF3212)
EHHHJOPM_03163 1.4e-187 yfmJ S N-terminal domain of oxidoreductase
EHHHJOPM_03164 2.1e-41 yfmK 2.3.1.128 K acetyltransferase
EHHHJOPM_03165 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
EHHHJOPM_03166 3.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHHHJOPM_03167 7.5e-206 yfmO EGP Major facilitator Superfamily
EHHHJOPM_03168 1.8e-69 yfmP K transcriptional
EHHHJOPM_03169 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EHHHJOPM_03170 1.2e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
EHHHJOPM_03171 5.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
EHHHJOPM_03172 7.5e-107 yfmS NT chemotaxis protein
EHHHJOPM_03173 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHHHJOPM_03174 3e-246 yfnA E amino acid
EHHHJOPM_03175 6.8e-218 fsr P COG0477 Permeases of the major facilitator superfamily
EHHHJOPM_03176 1.5e-185 yfnD M Nucleotide-diphospho-sugar transferase
EHHHJOPM_03177 1.4e-220 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
EHHHJOPM_03178 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
EHHHJOPM_03179 7.1e-172 yfnG 4.2.1.45 M dehydratase
EHHHJOPM_03180 1.8e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
EHHHJOPM_03181 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EHHHJOPM_03182 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
EHHHJOPM_03183 7.5e-197 yetN S Protein of unknown function (DUF3900)
EHHHJOPM_03184 7.9e-205 yetM CH FAD binding domain
EHHHJOPM_03185 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
EHHHJOPM_03186 2.6e-104 yetJ S Belongs to the BI1 family
EHHHJOPM_03187 5.3e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
EHHHJOPM_03188 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
EHHHJOPM_03189 2.4e-153 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EHHHJOPM_03190 3.4e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHHJOPM_03191 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
EHHHJOPM_03192 2.1e-120 yetF S membrane
EHHHJOPM_03194 5e-93 yesJ K Acetyltransferase (GNAT) family
EHHHJOPM_03195 8.9e-104 cotJC P Spore Coat
EHHHJOPM_03196 1.3e-44 cotJB S CotJB protein
EHHHJOPM_03197 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
EHHHJOPM_03198 4.5e-107 aadK G Streptomycin adenylyltransferase
EHHHJOPM_03200 9.4e-127 yeeN K transcriptional regulatory protein
EHHHJOPM_03201 1.2e-19
EHHHJOPM_03202 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
EHHHJOPM_03203 2.7e-85 S Protein of unknown function, DUF600
EHHHJOPM_03204 2.2e-138 cylB V ABC-2 type transporter
EHHHJOPM_03205 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
EHHHJOPM_03206 4.5e-21
EHHHJOPM_03207 3.9e-246 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHHHJOPM_03208 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EHHHJOPM_03209 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHHHJOPM_03210 1.3e-151 yerO K Transcriptional regulator
EHHHJOPM_03211 3.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHHHJOPM_03212 4.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EHHHJOPM_03213 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EHHHJOPM_03214 1.4e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHHHJOPM_03215 1.3e-120 sapB S MgtC SapB transporter
EHHHJOPM_03216 6.8e-192 yerI S homoserine kinase type II (protein kinase fold)
EHHHJOPM_03217 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
EHHHJOPM_03218 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHHHJOPM_03219 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EHHHJOPM_03220 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EHHHJOPM_03221 7.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
EHHHJOPM_03222 2.4e-50 yerC S protein conserved in bacteria
EHHHJOPM_03223 1.5e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
EHHHJOPM_03224 0.0 yerA 3.5.4.2 F adenine deaminase
EHHHJOPM_03225 2.6e-25 S Protein of unknown function (DUF2892)
EHHHJOPM_03226 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
EHHHJOPM_03227 5.6e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EHHHJOPM_03228 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHHHJOPM_03229 1.1e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EHHHJOPM_03230 4.4e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHHHJOPM_03231 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHHHJOPM_03232 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHHHJOPM_03233 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHHHJOPM_03234 7e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EHHHJOPM_03235 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHHHJOPM_03236 3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHHHJOPM_03237 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHHHJOPM_03238 5.5e-29 yebG S NETI protein
EHHHJOPM_03239 7.5e-92 yebE S UPF0316 protein
EHHHJOPM_03241 1.5e-125 yebC M Membrane
EHHHJOPM_03242 8.1e-209 pbuG S permease
EHHHJOPM_03243 2.1e-247 S Domain of unknown function (DUF4179)
EHHHJOPM_03244 1.1e-92 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EHHHJOPM_03245 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EHHHJOPM_03246 0.0 yebA E COG1305 Transglutaminase-like enzymes
EHHHJOPM_03247 3.3e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EHHHJOPM_03248 1.5e-175 yeaC S COG0714 MoxR-like ATPases
EHHHJOPM_03249 4.8e-244 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
EHHHJOPM_03250 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
EHHHJOPM_03251 7.2e-35 ydjO S Cold-inducible protein YdjO
EHHHJOPM_03253 2e-133 ydjN U Involved in the tonB-independent uptake of proteins
EHHHJOPM_03254 1.2e-61 ydjM M Lytic transglycolase
EHHHJOPM_03255 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
EHHHJOPM_03256 1.2e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
EHHHJOPM_03257 1.4e-145 rsiV S Protein of unknown function (DUF3298)
EHHHJOPM_03258 0.0 yrhL I Acyltransferase family
EHHHJOPM_03259 5.3e-144 ydjI S virion core protein (lumpy skin disease virus)
EHHHJOPM_03260 1.1e-117 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
EHHHJOPM_03261 1.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHHHJOPM_03262 1.3e-112 pspA KT Phage shock protein A
EHHHJOPM_03263 1.2e-30 yjdJ S Domain of unknown function (DUF4306)
EHHHJOPM_03264 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
EHHHJOPM_03265 1.1e-248 gutA G MFS/sugar transport protein
EHHHJOPM_03266 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
EHHHJOPM_03267 0.0 K NB-ARC domain
EHHHJOPM_03268 2.6e-62
EHHHJOPM_03271 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
EHHHJOPM_03272 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EHHHJOPM_03273 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHHHJOPM_03274 4.3e-127 ydiL S CAAX protease self-immunity
EHHHJOPM_03275 1.7e-27 ydiK S Domain of unknown function (DUF4305)
EHHHJOPM_03276 9.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHHHJOPM_03277 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EHHHJOPM_03278 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EHHHJOPM_03279 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EHHHJOPM_03280 0.0 ydiF S ABC transporter
EHHHJOPM_03281 2.1e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHHHJOPM_03282 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EHHHJOPM_03283 4.2e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
EHHHJOPM_03284 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
EHHHJOPM_03285 3.3e-183 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EHHHJOPM_03287 7.8e-08
EHHHJOPM_03288 3.4e-39 S COG NOG14552 non supervised orthologous group
EHHHJOPM_03291 1.7e-249 iolT EGP Major facilitator Superfamily
EHHHJOPM_03292 7.5e-183 yhfP 1.1.1.1 C Quinone oxidoreductase
EHHHJOPM_03293 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
EHHHJOPM_03294 1.9e-163 ydhU P Catalase
EHHHJOPM_03295 9.3e-297 yveA E amino acid
EHHHJOPM_03296 2.9e-102 yvdT K Transcriptional regulator
EHHHJOPM_03297 8.6e-51 ykkC P Small Multidrug Resistance protein
EHHHJOPM_03298 7.7e-49 sugE P Small Multidrug Resistance protein
EHHHJOPM_03299 8.2e-216 yeaN P COG2807 Cyanate permease
EHHHJOPM_03300 9.9e-118 K FCD
EHHHJOPM_03301 1.5e-132 ydhQ K UTRA
EHHHJOPM_03302 2e-195 pbuE EGP Major facilitator Superfamily
EHHHJOPM_03303 5.5e-98 ydhK M Protein of unknown function (DUF1541)
EHHHJOPM_03305 8.4e-57 pbpE V Beta-lactamase
EHHHJOPM_03306 5.7e-194 pbpE V Beta-lactamase
EHHHJOPM_03309 5e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EHHHJOPM_03310 2.6e-118 ydhC K FCD
EHHHJOPM_03311 6.8e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
EHHHJOPM_03312 9.7e-105 S Alpha/beta hydrolase family
EHHHJOPM_03313 8.1e-111 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
EHHHJOPM_03314 1.1e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EHHHJOPM_03315 2.2e-148 bltR K helix_turn_helix, mercury resistance
EHHHJOPM_03316 2.2e-81 bltD 2.3.1.57 K FR47-like protein
EHHHJOPM_03317 9.4e-122 ydhB S membrane transporter protein
EHHHJOPM_03318 5e-156 K Helix-turn-helix XRE-family like proteins
EHHHJOPM_03319 1.1e-223 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EHHHJOPM_03320 3.9e-210 tcaB EGP Major facilitator Superfamily
EHHHJOPM_03321 2.3e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
EHHHJOPM_03322 1.2e-149 S Uncharacterized protein conserved in bacteria (DUF2179)
EHHHJOPM_03323 5.7e-97 ynaD J Acetyltransferase (GNAT) domain
EHHHJOPM_03324 1.8e-298 expZ S ABC transporter
EHHHJOPM_03325 1.8e-133 puuD S Peptidase C26
EHHHJOPM_03326 0.0 ydfJ S drug exporters of the RND superfamily
EHHHJOPM_03327 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EHHHJOPM_03328 6.2e-214 ydfH 2.7.13.3 T Histidine kinase
EHHHJOPM_03329 1.4e-34 yraG
EHHHJOPM_03330 8.4e-63 yraF M Spore coat protein
EHHHJOPM_03331 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EHHHJOPM_03332 5.4e-24 yraE
EHHHJOPM_03333 1.4e-47 yraD M Spore coat protein
EHHHJOPM_03334 1.6e-100 ydeS K Transcriptional regulator
EHHHJOPM_03335 2.6e-174 ydeR EGP Major facilitator Superfamily
EHHHJOPM_03337 3e-113 paiB K Transcriptional regulator
EHHHJOPM_03338 4.9e-257 K helix_turn_helix gluconate operon transcriptional repressor
EHHHJOPM_03339 2.3e-224 mleN_2 C antiporter
EHHHJOPM_03340 1.8e-66 yraB K helix_turn_helix, mercury resistance
EHHHJOPM_03341 4.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
EHHHJOPM_03342 4e-165 S Sodium Bile acid symporter family
EHHHJOPM_03343 4.5e-51 ydeH
EHHHJOPM_03344 3.4e-194 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
EHHHJOPM_03346 7.4e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
EHHHJOPM_03347 1.8e-14 ykkA S Protein of unknown function (DUF664)
EHHHJOPM_03350 4e-195 trkA P Oxidoreductase
EHHHJOPM_03351 1.1e-167 czcD P COG1230 Co Zn Cd efflux system component
EHHHJOPM_03352 1.2e-09 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EHHHJOPM_03353 6.6e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
EHHHJOPM_03356 5.5e-28 3.6.1.55 F Belongs to the Nudix hydrolase family
EHHHJOPM_03357 3.3e-191 ydeG EGP Major facilitator superfamily
EHHHJOPM_03358 4.9e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHHHJOPM_03359 1.2e-174 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EHHHJOPM_03360 7.6e-126 rhaS5 K helix_turn_helix, arabinose operon control protein
EHHHJOPM_03361 5.3e-164 E Peptidase dimerisation domain
EHHHJOPM_03362 3.8e-142 sdaC E Serine transporter
EHHHJOPM_03363 1.7e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
EHHHJOPM_03364 2.7e-67 K COG1802 Transcriptional regulators
EHHHJOPM_03365 2.5e-116 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
EHHHJOPM_03366 2.1e-82 S DinB superfamily
EHHHJOPM_03367 2.6e-180 S Patatin-like phospholipase
EHHHJOPM_03368 4.1e-50 K Transcriptional regulator PadR-like family
EHHHJOPM_03369 4.1e-101 S Protein of unknown function (DUF2812)
EHHHJOPM_03370 3.7e-117 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
EHHHJOPM_03371 1.1e-117 yrkJ S membrane transporter protein
EHHHJOPM_03372 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
EHHHJOPM_03373 3.4e-200 yrkH P Rhodanese Homology Domain
EHHHJOPM_03374 5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
EHHHJOPM_03375 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
EHHHJOPM_03376 9.2e-40 yrkD S protein conserved in bacteria
EHHHJOPM_03377 1.4e-30 cspL K Cold shock
EHHHJOPM_03378 4.2e-110 ywnB S NAD(P)H-binding
EHHHJOPM_03379 3.1e-72 ywnA K Transcriptional regulator
EHHHJOPM_03380 3.5e-63 yyaQ S YjbR
EHHHJOPM_03381 1e-72 maoC I N-terminal half of MaoC dehydratase
EHHHJOPM_03382 5.4e-86 S Domain of unknown function with cystatin-like fold (DUF4467)
EHHHJOPM_03383 1.4e-48 ohrR K Transcriptional regulator
EHHHJOPM_03385 4.8e-46 ohrB O OsmC-like protein
EHHHJOPM_03386 3.8e-136 I esterase
EHHHJOPM_03387 9.8e-229 proP EGP Transporter
EHHHJOPM_03388 2.3e-150 S Serine aminopeptidase, S33
EHHHJOPM_03389 1.7e-201 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EHHHJOPM_03390 2.9e-49 S SMI1-KNR4 cell-wall
EHHHJOPM_03392 2.3e-79 S FRG
EHHHJOPM_03394 1.6e-25 S response regulator aspartate phosphatase
EHHHJOPM_03395 3.7e-31 S response regulator aspartate phosphatase
EHHHJOPM_03397 6.5e-55 ydcQ D Ftsk spoiiie family protein
EHHHJOPM_03405 4.3e-58 ydcK S Belongs to the SprT family
EHHHJOPM_03406 1.7e-14
EHHHJOPM_03407 0.0 yhgF K COG2183 Transcriptional accessory protein
EHHHJOPM_03408 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
EHHHJOPM_03409 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHHHJOPM_03410 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EHHHJOPM_03411 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
EHHHJOPM_03412 1.7e-187 rsbU 3.1.3.3 KT phosphatase
EHHHJOPM_03413 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EHHHJOPM_03414 1.8e-57 rsbS T antagonist
EHHHJOPM_03415 6.1e-146 rsbR T Positive regulator of sigma-B
EHHHJOPM_03416 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
EHHHJOPM_03417 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EHHHJOPM_03418 2.2e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHHHJOPM_03419 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
EHHHJOPM_03420 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EHHHJOPM_03421 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
EHHHJOPM_03422 4.5e-261 ydbT S Membrane
EHHHJOPM_03423 5.1e-60 ydbS S Bacterial PH domain
EHHHJOPM_03424 5.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EHHHJOPM_03425 1.2e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EHHHJOPM_03426 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EHHHJOPM_03427 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EHHHJOPM_03428 3.1e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHHHJOPM_03429 5.8e-09 S Fur-regulated basic protein A
EHHHJOPM_03430 1.5e-10 S Fur-regulated basic protein B
EHHHJOPM_03431 3e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
EHHHJOPM_03432 4.6e-52 ydbL
EHHHJOPM_03433 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EHHHJOPM_03434 6.1e-171 ydbJ V ABC transporter, ATP-binding protein
EHHHJOPM_03435 4e-158 ydbI S AI-2E family transporter
EHHHJOPM_03436 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHHHJOPM_03437 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
EHHHJOPM_03438 1.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
EHHHJOPM_03439 1.9e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EHHHJOPM_03440 1.2e-154 ydbD P Catalase
EHHHJOPM_03441 8.5e-60 ydbC S Domain of unknown function (DUF4937
EHHHJOPM_03442 3.4e-58 ydbB G Cupin domain
EHHHJOPM_03444 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
EHHHJOPM_03445 7.8e-53 yvaE P Small Multidrug Resistance protein
EHHHJOPM_03446 1.2e-70 yvaD S Family of unknown function (DUF5360)
EHHHJOPM_03447 6.5e-34 ydaT
EHHHJOPM_03450 2.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
EHHHJOPM_03451 1.8e-38
EHHHJOPM_03452 8.5e-97
EHHHJOPM_03453 4.2e-74
EHHHJOPM_03455 4.2e-12
EHHHJOPM_03456 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
EHHHJOPM_03457 2.2e-73 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EHHHJOPM_03458 0.0 ydaO E amino acid
EHHHJOPM_03459 0.0 ydaN S Bacterial cellulose synthase subunit
EHHHJOPM_03460 7.2e-231 ydaM M Glycosyl transferase family group 2
EHHHJOPM_03461 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
EHHHJOPM_03462 4.3e-147 ydaK T Diguanylate cyclase, GGDEF domain
EHHHJOPM_03463 1.6e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
EHHHJOPM_03464 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHHHJOPM_03465 4.3e-74 lrpC K Transcriptional regulator
EHHHJOPM_03466 1.3e-47 ydzA EGP Major facilitator Superfamily
EHHHJOPM_03467 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EHHHJOPM_03468 1.2e-76 ydaG 1.4.3.5 S general stress protein
EHHHJOPM_03469 3.2e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EHHHJOPM_03470 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
EHHHJOPM_03471 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHHJOPM_03472 5.5e-286 ydaB IQ acyl-CoA ligase
EHHHJOPM_03473 0.0 mtlR K transcriptional regulator, MtlR
EHHHJOPM_03474 3.7e-173 ydhF S Oxidoreductase
EHHHJOPM_03475 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
EHHHJOPM_03476 5.1e-56 yczJ S biosynthesis
EHHHJOPM_03478 1e-116 ycsK E anatomical structure formation involved in morphogenesis
EHHHJOPM_03479 3.7e-129 kipR K Transcriptional regulator
EHHHJOPM_03480 1.2e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
EHHHJOPM_03481 5.6e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
EHHHJOPM_03482 4.8e-148 ycsI S Belongs to the D-glutamate cyclase family
EHHHJOPM_03483 5.7e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
EHHHJOPM_03484 1e-139 ycsF S Belongs to the UPF0271 (lamB) family
EHHHJOPM_03485 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
EHHHJOPM_03487 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
EHHHJOPM_03488 7.1e-206 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
EHHHJOPM_03489 5.2e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EHHHJOPM_03490 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
EHHHJOPM_03491 1.6e-55
EHHHJOPM_03492 9.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
EHHHJOPM_03493 2e-297 ycnJ P protein, homolog of Cu resistance protein CopC
EHHHJOPM_03494 2.3e-97 ycnI S protein conserved in bacteria
EHHHJOPM_03495 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EHHHJOPM_03496 3.6e-149 glcU U Glucose uptake
EHHHJOPM_03497 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EHHHJOPM_03498 1.9e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHHHJOPM_03499 4.4e-261 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EHHHJOPM_03500 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
EHHHJOPM_03501 1e-44 ycnE S Monooxygenase
EHHHJOPM_03502 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
EHHHJOPM_03503 3e-151 ycnC K Transcriptional regulator
EHHHJOPM_03504 2.1e-247 ycnB EGP Major facilitator Superfamily
EHHHJOPM_03505 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
EHHHJOPM_03506 4e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
EHHHJOPM_03507 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHHJOPM_03508 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHHJOPM_03509 1.6e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
EHHHJOPM_03511 1.6e-80 S aspartate phosphatase
EHHHJOPM_03512 4.1e-259 T PhoQ Sensor
EHHHJOPM_03513 7.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EHHHJOPM_03514 1.4e-227 yclI V ABC transporter (permease) YclI
EHHHJOPM_03515 1.6e-120 yclH P ABC transporter
EHHHJOPM_03516 1.9e-250 yxeQ S MmgE/PrpD family
EHHHJOPM_03517 7.8e-216 yxeP 3.5.1.47 E hydrolase activity
EHHHJOPM_03518 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
EHHHJOPM_03519 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
EHHHJOPM_03520 2.1e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
EHHHJOPM_03521 1.1e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EHHHJOPM_03522 1.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHHJOPM_03523 1.1e-195 gerKB F Spore germination protein
EHHHJOPM_03524 5.2e-234 gerKC S spore germination
EHHHJOPM_03525 7.8e-294 gerKA EG Spore germination protein
EHHHJOPM_03527 9.2e-277 yclG M Pectate lyase superfamily protein
EHHHJOPM_03528 1.2e-269 dtpT E amino acid peptide transporter
EHHHJOPM_03529 1.3e-76 yclD
EHHHJOPM_03530 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
EHHHJOPM_03531 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EHHHJOPM_03532 9.4e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EHHHJOPM_03533 3.9e-159 bsdA K LysR substrate binding domain
EHHHJOPM_03534 1.2e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
EHHHJOPM_03535 6.3e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
EHHHJOPM_03536 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
EHHHJOPM_03537 1.7e-108 yczE S membrane
EHHHJOPM_03538 1.9e-129 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
EHHHJOPM_03539 6.1e-249 bamJ E Aminotransferase class I and II
EHHHJOPM_03540 3.4e-140 srfAD Q thioesterase
EHHHJOPM_03541 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
EHHHJOPM_03542 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EHHHJOPM_03543 4.5e-61 hxlR K transcriptional
EHHHJOPM_03544 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
EHHHJOPM_03545 1.6e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
EHHHJOPM_03546 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
EHHHJOPM_03547 5.7e-65 nin S Competence protein J (ComJ)
EHHHJOPM_03548 9e-11 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EHHHJOPM_03549 1.3e-48 S Protein of unknown function (DUF2680)
EHHHJOPM_03550 1.1e-72 yckC S membrane
EHHHJOPM_03551 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EHHHJOPM_03552 7.8e-227 yciC S GTPases (G3E family)
EHHHJOPM_03553 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHHHJOPM_03554 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
EHHHJOPM_03555 7.1e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
EHHHJOPM_03556 2.4e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EHHHJOPM_03557 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
EHHHJOPM_03558 1.2e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHHHJOPM_03559 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
EHHHJOPM_03560 8.7e-170 ycgM E Proline dehydrogenase
EHHHJOPM_03561 8.9e-147 ycgL S Predicted nucleotidyltransferase
EHHHJOPM_03562 6.5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
EHHHJOPM_03563 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHHHJOPM_03564 9.1e-221 G COG0477 Permeases of the major facilitator superfamily
EHHHJOPM_03565 2.5e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
EHHHJOPM_03566 6.2e-108 tmrB S AAA domain
EHHHJOPM_03568 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EHHHJOPM_03569 1.3e-113 ycgI S Domain of unknown function (DUF1989)
EHHHJOPM_03570 5.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
EHHHJOPM_03571 2.2e-150 yqcI S YqcI/YcgG family
EHHHJOPM_03572 4.7e-114 ycgF E Lysine exporter protein LysE YggA
EHHHJOPM_03573 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
EHHHJOPM_03574 8.1e-261 mdr EGP Major facilitator Superfamily
EHHHJOPM_03575 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EHHHJOPM_03576 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
EHHHJOPM_03577 1.5e-80 ycgB
EHHHJOPM_03578 5.5e-227 ycgA S Membrane
EHHHJOPM_03579 2.4e-209 amhX S amidohydrolase
EHHHJOPM_03580 1.5e-163 opuAC E glycine betaine
EHHHJOPM_03581 1.6e-138 opuAB P glycine betaine
EHHHJOPM_03582 3.9e-229 proV 3.6.3.32 E glycine betaine
EHHHJOPM_03583 2.6e-214 naiP P Uncharacterised MFS-type transporter YbfB
EHHHJOPM_03584 2.3e-193 yceH P Belongs to the TelA family
EHHHJOPM_03585 0.0 yceG S Putative component of 'biosynthetic module'
EHHHJOPM_03586 9.7e-138 terC P Protein of unknown function (DUF475)
EHHHJOPM_03587 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
EHHHJOPM_03588 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
EHHHJOPM_03589 2.8e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
EHHHJOPM_03590 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EHHHJOPM_03591 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EHHHJOPM_03592 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EHHHJOPM_03593 2.3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
EHHHJOPM_03594 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
EHHHJOPM_03595 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
EHHHJOPM_03596 1e-188 S response regulator aspartate phosphatase
EHHHJOPM_03597 6.4e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
EHHHJOPM_03598 3.3e-266 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
EHHHJOPM_03599 1.4e-256 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
EHHHJOPM_03600 1.5e-175 ycdA S Domain of unknown function (DUF5105)
EHHHJOPM_03601 6.8e-170 yccK C Aldo keto reductase
EHHHJOPM_03602 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
EHHHJOPM_03603 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHHHJOPM_03604 1.8e-139 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EHHHJOPM_03605 5.2e-45 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EHHHJOPM_03606 6.5e-99 yxaF K Transcriptional regulator
EHHHJOPM_03607 1e-241 lmrB EGP the major facilitator superfamily
EHHHJOPM_03608 7.9e-205 ycbU E Selenocysteine lyase
EHHHJOPM_03609 3.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHHHJOPM_03610 9.2e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHHHJOPM_03611 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EHHHJOPM_03612 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
EHHHJOPM_03613 5.3e-77 sleB 3.5.1.28 M Cell wall
EHHHJOPM_03614 5.6e-62 ycbP S Protein of unknown function (DUF2512)
EHHHJOPM_03615 3.5e-55 traF CO Thioredoxin
EHHHJOPM_03616 1.5e-62 mhqP S DoxX
EHHHJOPM_03617 1.3e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
EHHHJOPM_03618 1.7e-108 ydfN C nitroreductase
EHHHJOPM_03619 2.3e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EHHHJOPM_03620 1.8e-25 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
EHHHJOPM_03621 3.3e-124 ycbJ S Macrolide 2'-phosphotransferase
EHHHJOPM_03622 9.1e-170 glnL T Regulator
EHHHJOPM_03623 5.7e-207 phoQ 2.7.13.3 T Histidine kinase
EHHHJOPM_03624 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
EHHHJOPM_03625 2.7e-258 agcS E Sodium alanine symporter
EHHHJOPM_03626 1.6e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
EHHHJOPM_03627 1.5e-256 mmuP E amino acid
EHHHJOPM_03628 2.1e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
EHHHJOPM_03629 1.6e-214 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EHHHJOPM_03630 2.5e-191 yceA S Belongs to the UPF0176 family
EHHHJOPM_03631 6.1e-42 ybfN
EHHHJOPM_03632 4.7e-151 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EHHHJOPM_03633 1.9e-86 ybfM S SNARE associated Golgi protein
EHHHJOPM_03634 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHHHJOPM_03635 1.2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHHHJOPM_03636 2.3e-193 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
EHHHJOPM_03637 1.2e-82 K Helix-turn-helix XRE-family like proteins
EHHHJOPM_03638 9.2e-32
EHHHJOPM_03639 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
EHHHJOPM_03641 3.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
EHHHJOPM_03642 1e-16 S Protein of unknown function (DUF2651)
EHHHJOPM_03643 1.7e-259 glpT G -transporter
EHHHJOPM_03644 3.7e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
EHHHJOPM_03645 2.3e-16 S Protein of unknown function (DUF2651)
EHHHJOPM_03646 6.5e-56
EHHHJOPM_03647 5.5e-292 ybeC E amino acid
EHHHJOPM_03648 9.2e-40 ybyB
EHHHJOPM_03649 8e-107 yqeB
EHHHJOPM_03650 7.5e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
EHHHJOPM_03651 2.5e-75 S Domain of unknown function (DUF4879)
EHHHJOPM_03652 9.2e-23
EHHHJOPM_03653 2.9e-194 V ABC-2 family transporter protein
EHHHJOPM_03654 1.7e-202 V COG0842 ABC-type multidrug transport system, permease component
EHHHJOPM_03655 2.5e-164 V COG1131 ABC-type multidrug transport system, ATPase component
EHHHJOPM_03656 4.6e-109 KT LuxR family transcriptional regulator
EHHHJOPM_03657 4.7e-197 T COG4585 Signal transduction histidine kinase
EHHHJOPM_03658 6.1e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EHHHJOPM_03659 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
EHHHJOPM_03660 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
EHHHJOPM_03661 5.8e-51 S LrgA family
EHHHJOPM_03662 2.9e-93 yxaC M effector of murein hydrolase
EHHHJOPM_03663 9.6e-163 dkgB S Aldo/keto reductase family
EHHHJOPM_03664 2.8e-18 dkgB S Aldo/keto reductase family
EHHHJOPM_03665 2.7e-88 2.1.1.113 H DNA methylase
EHHHJOPM_03667 2.4e-12
EHHHJOPM_03669 5.3e-42 D AAA domain
EHHHJOPM_03670 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EHHHJOPM_03671 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHHHJOPM_03672 1.3e-223 ybbR S protein conserved in bacteria
EHHHJOPM_03673 3.9e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EHHHJOPM_03674 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EHHHJOPM_03675 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
EHHHJOPM_03681 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
EHHHJOPM_03682 7.7e-85 ybbJ J acetyltransferase
EHHHJOPM_03683 9.2e-159 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHHHJOPM_03684 2.7e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
EHHHJOPM_03685 5.8e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
EHHHJOPM_03686 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
EHHHJOPM_03687 3.3e-236 ybbC 3.2.1.52 S protein conserved in bacteria
EHHHJOPM_03688 3e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
EHHHJOPM_03689 2e-172 feuA P Iron-uptake system-binding protein
EHHHJOPM_03690 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHHJOPM_03691 6.1e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHHHJOPM_03692 6e-108 ybbA S Putative esterase
EHHHJOPM_03693 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
EHHHJOPM_03694 6.7e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
EHHHJOPM_03695 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
EHHHJOPM_03696 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
EHHHJOPM_03697 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHHHJOPM_03698 4.2e-220 glcP G Major Facilitator Superfamily
EHHHJOPM_03699 3.4e-39 S COG NOG14552 non supervised orthologous group
EHHHJOPM_03704 2e-08
EHHHJOPM_03707 1.3e-07
EHHHJOPM_03709 3.4e-39 S COG NOG14552 non supervised orthologous group
EHHHJOPM_03712 1.6e-08
EHHHJOPM_03715 3.4e-39 S COG NOG14552 non supervised orthologous group
EHHHJOPM_03716 2.1e-132 pdaB 3.5.1.104 G Polysaccharide deacetylase
EHHHJOPM_03717 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
EHHHJOPM_03718 1.7e-75 gerD
EHHHJOPM_03719 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EHHHJOPM_03720 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
EHHHJOPM_03721 9.4e-77 ybaK S Protein of unknown function (DUF2521)
EHHHJOPM_03722 1.2e-82 yizA S Damage-inducible protein DinB
EHHHJOPM_03723 3.1e-144 ybaJ Q Methyltransferase domain
EHHHJOPM_03724 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
EHHHJOPM_03725 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHHHJOPM_03726 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EHHHJOPM_03727 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHHHJOPM_03728 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHHHJOPM_03729 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EHHHJOPM_03730 4.7e-58 rplQ J Ribosomal protein L17
EHHHJOPM_03731 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHHHJOPM_03732 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHHHJOPM_03733 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHHHJOPM_03734 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EHHHJOPM_03735 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHHHJOPM_03736 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
EHHHJOPM_03737 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EHHHJOPM_03738 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EHHHJOPM_03739 4.1e-72 rplO J binds to the 23S rRNA
EHHHJOPM_03740 1.9e-23 rpmD J Ribosomal protein L30
EHHHJOPM_03741 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EHHHJOPM_03742 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EHHHJOPM_03743 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHHHJOPM_03744 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHHHJOPM_03745 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHHHJOPM_03746 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHHHJOPM_03747 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHHHJOPM_03748 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHHHJOPM_03749 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHHHJOPM_03750 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
EHHHJOPM_03751 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EHHHJOPM_03752 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHHHJOPM_03753 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHHHJOPM_03754 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHHHJOPM_03755 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHHHJOPM_03756 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EHHHJOPM_03757 3e-105 rplD J Forms part of the polypeptide exit tunnel
EHHHJOPM_03758 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHHHJOPM_03759 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
EHHHJOPM_03760 1.8e-181 ybaC 3.4.11.5 S Alpha/beta hydrolase family
EHHHJOPM_03761 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHHHJOPM_03762 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHHHJOPM_03763 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EHHHJOPM_03764 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EHHHJOPM_03765 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
EHHHJOPM_03766 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHHHJOPM_03767 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHHHJOPM_03768 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
EHHHJOPM_03769 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EHHHJOPM_03770 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHHHJOPM_03771 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EHHHJOPM_03772 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHHHJOPM_03773 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
EHHHJOPM_03774 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EHHHJOPM_03775 8.9e-116 sigH K Belongs to the sigma-70 factor family
EHHHJOPM_03776 4.2e-89 yacP S RNA-binding protein containing a PIN domain
EHHHJOPM_03777 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHHHJOPM_03778 4e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EHHHJOPM_03779 1.8e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EHHHJOPM_03780 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
EHHHJOPM_03781 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHHHJOPM_03782 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EHHHJOPM_03783 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EHHHJOPM_03784 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
EHHHJOPM_03785 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EHHHJOPM_03786 1.1e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHHHJOPM_03787 0.0 clpC O Belongs to the ClpA ClpB family
EHHHJOPM_03788 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EHHHJOPM_03789 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
EHHHJOPM_03790 7.5e-77 ctsR K Belongs to the CtsR family
EHHHJOPM_03791 3.4e-39 S COG NOG14552 non supervised orthologous group
EHHHJOPM_03796 2e-08
EHHHJOPM_03799 1.3e-07
EHHHJOPM_03801 3.4e-39 S COG NOG14552 non supervised orthologous group
EHHHJOPM_03802 3.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EHHHJOPM_03803 7.8e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHHHJOPM_03804 4.5e-29 yazB K transcriptional
EHHHJOPM_03805 1.1e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHHHJOPM_03806 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHHHJOPM_03807 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHHHJOPM_03808 1.9e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
EHHHJOPM_03809 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
EHHHJOPM_03810 8.9e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHHHJOPM_03811 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EHHHJOPM_03812 3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
EHHHJOPM_03813 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHHHJOPM_03814 3.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EHHHJOPM_03815 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHHHJOPM_03816 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EHHHJOPM_03817 3e-270 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EHHHJOPM_03818 1.4e-184 KLT serine threonine protein kinase
EHHHJOPM_03819 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
EHHHJOPM_03820 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
EHHHJOPM_03823 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
EHHHJOPM_03824 4.1e-57 divIC D Septum formation initiator
EHHHJOPM_03825 2.9e-103 yabQ S spore cortex biosynthesis protein
EHHHJOPM_03826 1.9e-49 yabP S Sporulation protein YabP
EHHHJOPM_03827 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EHHHJOPM_03828 1.8e-273 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EHHHJOPM_03829 5.9e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EHHHJOPM_03830 6.2e-91 spoVT K stage V sporulation protein
EHHHJOPM_03831 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHHHJOPM_03832 3.7e-40 yabK S Peptide ABC transporter permease
EHHHJOPM_03833 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EHHHJOPM_03834 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHHHJOPM_03835 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHHHJOPM_03836 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHHHJOPM_03837 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EHHHJOPM_03838 1.5e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
EHHHJOPM_03839 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
EHHHJOPM_03840 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHHHJOPM_03841 2.9e-27 sspF S DNA topological change
EHHHJOPM_03842 7.8e-39 veg S protein conserved in bacteria
EHHHJOPM_03843 8.4e-146 yabG S peptidase
EHHHJOPM_03844 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EHHHJOPM_03845 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EHHHJOPM_03846 2.7e-231 rpfB GH23 T protein conserved in bacteria
EHHHJOPM_03847 4.5e-143 tatD L hydrolase, TatD
EHHHJOPM_03848 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHHHJOPM_03849 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
EHHHJOPM_03850 1.4e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHHHJOPM_03851 5.2e-47 yazA L endonuclease containing a URI domain
EHHHJOPM_03852 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
EHHHJOPM_03853 7.7e-37 yabA L Involved in initiation control of chromosome replication
EHHHJOPM_03854 8.8e-145 yaaT S stage 0 sporulation protein
EHHHJOPM_03855 3.7e-182 holB 2.7.7.7 L DNA polymerase III
EHHHJOPM_03856 1.2e-71 yaaR S protein conserved in bacteria
EHHHJOPM_03857 7.5e-55 yaaQ S protein conserved in bacteria
EHHHJOPM_03858 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHHHJOPM_03859 6.4e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
EHHHJOPM_03860 3.5e-189 yaaN P Belongs to the TelA family
EHHHJOPM_03861 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EHHHJOPM_03862 3.8e-30 csfB S Inhibitor of sigma-G Gin
EHHHJOPM_03865 3.4e-39 S COG NOG14552 non supervised orthologous group
EHHHJOPM_03866 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
EHHHJOPM_03867 3.6e-32 yaaL S Protein of unknown function (DUF2508)
EHHHJOPM_03868 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHHHJOPM_03869 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHHHJOPM_03870 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EHHHJOPM_03871 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EHHHJOPM_03872 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
EHHHJOPM_03873 1.7e-211 yaaH M Glycoside Hydrolase Family
EHHHJOPM_03874 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
EHHHJOPM_03875 1.6e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
EHHHJOPM_03876 1.3e-09
EHHHJOPM_03877 1.3e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EHHHJOPM_03878 3.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHHHJOPM_03879 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EHHHJOPM_03880 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EHHHJOPM_03881 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EHHHJOPM_03882 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EHHHJOPM_03883 6.3e-182 yaaC S YaaC-like Protein
EHHHJOPM_03886 3.4e-39 S COG NOG14552 non supervised orthologous group
EHHHJOPM_03887 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHHHJOPM_03888 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHHHJOPM_03889 8.1e-38 yaaB S Domain of unknown function (DUF370)
EHHHJOPM_03890 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHHHJOPM_03891 2.4e-33 yaaA S S4 domain
EHHHJOPM_03892 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EHHHJOPM_03893 1.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHHHJOPM_03895 6.8e-73 K Transcriptional regulator
EHHHJOPM_03896 8.7e-156 pre D plasmid recombination enzyme
EHHHJOPM_03897 2.4e-69 sipT 3.4.21.89 U Signal peptidase, peptidase S26
EHHHJOPM_03900 5.3e-184 L Replication protein
EHHHJOPM_03901 1.1e-86 S Tetratricopeptide repeat

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)