ORF_ID e_value Gene_name EC_number CAZy COGs Description
PHPGEFOM_00001 1.6e-66 brnQ U Component of the transport system for branched-chain amino acids
PHPGEFOM_00002 7e-25 5.99.1.2 T diguanylate cyclase
PHPGEFOM_00003 2.1e-72 5.99.1.2 T diguanylate cyclase
PHPGEFOM_00004 1.3e-08 T diguanylate cyclase
PHPGEFOM_00005 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
PHPGEFOM_00006 8.6e-37
PHPGEFOM_00007 1.4e-129 cobQ S glutamine amidotransferase
PHPGEFOM_00008 2.5e-27 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PHPGEFOM_00009 2.4e-144 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PHPGEFOM_00010 4e-144 ptp2 3.1.3.48 T Tyrosine phosphatase family
PHPGEFOM_00011 0.0 KLT serine threonine protein kinase
PHPGEFOM_00012 7.2e-289 V ABC-type multidrug transport system, ATPase and permease components
PHPGEFOM_00013 2e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
PHPGEFOM_00014 4.4e-91 ymdB S Macro domain protein
PHPGEFOM_00015 2.4e-34
PHPGEFOM_00016 2.4e-151
PHPGEFOM_00019 2.5e-264 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PHPGEFOM_00020 1e-257 P Sodium:sulfate symporter transmembrane region
PHPGEFOM_00022 4.4e-255 pipD M Peptidase family C69
PHPGEFOM_00023 8.7e-173 citR K Putative sugar-binding domain
PHPGEFOM_00024 6.3e-36 lysM M LysM domain
PHPGEFOM_00025 0.0 pepN 3.4.11.2 E aminopeptidase
PHPGEFOM_00026 2.9e-34 drgA C Nitroreductase family
PHPGEFOM_00027 5.9e-227 S Putative peptidoglycan binding domain
PHPGEFOM_00028 6e-117
PHPGEFOM_00029 4.2e-138 S Belongs to the UPF0246 family
PHPGEFOM_00030 2.1e-64 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
PHPGEFOM_00031 7.6e-120 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
PHPGEFOM_00032 2.1e-88 ygfC K transcriptional regulator (TetR family)
PHPGEFOM_00033 7.7e-186 hrtB V ABC transporter permease
PHPGEFOM_00034 4.4e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PHPGEFOM_00035 8e-171 K WYL domain
PHPGEFOM_00036 1.3e-66 S pyridoxamine 5-phosphate
PHPGEFOM_00037 5.9e-11 K LytTr DNA-binding domain
PHPGEFOM_00038 1.3e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHPGEFOM_00039 1.1e-139
PHPGEFOM_00041 2e-107
PHPGEFOM_00042 1.8e-116 V AAA domain, putative AbiEii toxin, Type IV TA system
PHPGEFOM_00043 1.1e-16
PHPGEFOM_00044 1.6e-276 pipD E Dipeptidase
PHPGEFOM_00045 1.5e-97 K WHG domain
PHPGEFOM_00046 9.9e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
PHPGEFOM_00047 5e-96 azr 1.5.1.36 S NADPH-dependent FMN reductase
PHPGEFOM_00048 3e-142 3.1.3.48 T Tyrosine phosphatase family
PHPGEFOM_00049 2e-188 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHPGEFOM_00050 5.3e-87 cvpA S Colicin V production protein
PHPGEFOM_00051 7.4e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PHPGEFOM_00052 3.3e-144 noc K Belongs to the ParB family
PHPGEFOM_00053 2.6e-138 soj D Sporulation initiation inhibitor
PHPGEFOM_00054 7.8e-155 spo0J K Belongs to the ParB family
PHPGEFOM_00055 2.5e-45 yyzM S Bacterial protein of unknown function (DUF951)
PHPGEFOM_00056 6.1e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PHPGEFOM_00057 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
PHPGEFOM_00058 0.0 V ABC transporter, ATP-binding protein
PHPGEFOM_00059 0.0 ndvA V ABC transporter
PHPGEFOM_00060 1e-122 K response regulator
PHPGEFOM_00061 1.6e-219 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
PHPGEFOM_00062 6.4e-298 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PHPGEFOM_00063 1.4e-144 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PHPGEFOM_00064 9.8e-135 fruR K DeoR C terminal sensor domain
PHPGEFOM_00065 4.5e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PHPGEFOM_00066 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
PHPGEFOM_00067 1.6e-143 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
PHPGEFOM_00068 8.6e-119 fhuC P ABC transporter
PHPGEFOM_00069 8e-135 znuB U ABC 3 transport family
PHPGEFOM_00070 8.3e-49 KT response to antibiotic
PHPGEFOM_00071 1.7e-100 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PHPGEFOM_00072 0.0 pepF E oligoendopeptidase F
PHPGEFOM_00073 2.9e-205 G Major Facilitator Superfamily
PHPGEFOM_00074 2.9e-38 L COG2963 Transposase and inactivated derivatives
PHPGEFOM_00075 1.1e-207 G Major Facilitator Superfamily
PHPGEFOM_00076 5.5e-115 K Bacterial regulatory proteins, tetR family
PHPGEFOM_00077 0.0 yhcA V ABC transporter, ATP-binding protein
PHPGEFOM_00078 3.8e-66 S Iron-sulphur cluster biosynthesis
PHPGEFOM_00079 7.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PHPGEFOM_00080 2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHPGEFOM_00081 2.2e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
PHPGEFOM_00082 4.4e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHPGEFOM_00084 7.4e-49
PHPGEFOM_00085 4.6e-227 ywhK S Membrane
PHPGEFOM_00086 4.7e-94 S ECF transporter, substrate-specific component
PHPGEFOM_00087 1.3e-99 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
PHPGEFOM_00089 1.6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PHPGEFOM_00090 1e-156 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PHPGEFOM_00091 7.5e-230 M ErfK YbiS YcfS YnhG
PHPGEFOM_00093 6.9e-25 bgl 3.2.1.21, 3.2.1.86 GT1 G beta-glucosidase activity
PHPGEFOM_00094 8.1e-232 isp2 L Transposase
PHPGEFOM_00095 8.4e-40 L Putative transposase DNA-binding domain
PHPGEFOM_00101 1.1e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PHPGEFOM_00102 3.8e-260 mdr EGP Sugar (and other) transporter
PHPGEFOM_00103 1.3e-119 3.6.1.27 I Acid phosphatase homologues
PHPGEFOM_00104 5.9e-206 L Putative transposase DNA-binding domain
PHPGEFOM_00105 1.1e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PHPGEFOM_00106 1.8e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PHPGEFOM_00107 1.4e-84 oppA E ABC transporter, substratebinding protein
PHPGEFOM_00108 1.6e-145 oppA E ABC transporter, substratebinding protein
PHPGEFOM_00109 4.6e-14 P nitric oxide dioxygenase activity
PHPGEFOM_00110 3.3e-83 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHPGEFOM_00112 3.8e-11 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
PHPGEFOM_00113 3e-19 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
PHPGEFOM_00114 1.6e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PHPGEFOM_00115 4.2e-214 pbpX1 V Beta-lactamase
PHPGEFOM_00116 4.6e-205 pbpX1 V Beta-lactamase
PHPGEFOM_00117 1.9e-14 L Helix-turn-helix domain
PHPGEFOM_00118 1.2e-45
PHPGEFOM_00119 9.1e-173
PHPGEFOM_00120 1.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHPGEFOM_00121 7.2e-112 rsmC 2.1.1.172 J Methyltransferase
PHPGEFOM_00122 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PHPGEFOM_00123 7.1e-288 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHPGEFOM_00124 3.5e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PHPGEFOM_00125 1.5e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PHPGEFOM_00126 1.4e-34 S Protein of unknown function (DUF2508)
PHPGEFOM_00127 2.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PHPGEFOM_00128 2.4e-53 yaaQ S Cyclic-di-AMP receptor
PHPGEFOM_00129 1e-159 holB 2.7.7.7 L DNA polymerase III
PHPGEFOM_00130 9.9e-55 yabA L Involved in initiation control of chromosome replication
PHPGEFOM_00131 8.6e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PHPGEFOM_00132 3.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
PHPGEFOM_00134 7.7e-58
PHPGEFOM_00135 8.5e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PHPGEFOM_00136 8e-205 pepO 3.4.24.71 O Peptidase family M13
PHPGEFOM_00137 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PHPGEFOM_00139 1.8e-116 S Membrane protein involved in the export of O-antigen and teichoic acid
PHPGEFOM_00140 4.7e-35 gpsA 1.1.1.94 I Rossmann-like domain
PHPGEFOM_00141 2.6e-41 S Core-2/I-Branching enzyme
PHPGEFOM_00142 8.7e-201 GT4 M Glycosyl transferases group 1
PHPGEFOM_00143 1.3e-102 L Transposase and inactivated derivatives
PHPGEFOM_00144 3.3e-39 L Transposase and inactivated derivatives
PHPGEFOM_00145 0.0 mcrB V AAA domain (dynein-related subfamily)
PHPGEFOM_00146 8.2e-119 mcrC V McrBC 5-methylcytosine restriction system component
PHPGEFOM_00147 7.4e-13 K Bacterial regulatory proteins, tetR family
PHPGEFOM_00148 2e-96 L nuclease
PHPGEFOM_00149 3.8e-154 F DNA/RNA non-specific endonuclease
PHPGEFOM_00150 3.3e-11
PHPGEFOM_00151 4.8e-175 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PHPGEFOM_00152 2.7e-59 K Bacterial regulatory proteins, tetR family
PHPGEFOM_00153 5.4e-197 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PHPGEFOM_00155 8.5e-39 higA K Helix-turn-helix XRE-family like proteins
PHPGEFOM_00156 4.1e-26 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PHPGEFOM_00157 8.8e-35 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PHPGEFOM_00158 5.4e-96 S ABC transporter, ATP-binding protein
PHPGEFOM_00159 2.8e-153 XK27_00670 S ABC transporter
PHPGEFOM_00161 4.9e-27
PHPGEFOM_00162 1.2e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
PHPGEFOM_00163 8.6e-95 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
PHPGEFOM_00164 5.2e-156 hipB K Helix-turn-helix
PHPGEFOM_00165 7.7e-154 I alpha/beta hydrolase fold
PHPGEFOM_00166 4.4e-106 yjbF S SNARE associated Golgi protein
PHPGEFOM_00167 6.1e-93 J Acetyltransferase (GNAT) domain
PHPGEFOM_00168 5.9e-236 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PHPGEFOM_00169 6.5e-99 K Sigma-70 region 2
PHPGEFOM_00170 2.4e-153 S Protein of unknown function (DUF3298)
PHPGEFOM_00171 4.2e-91 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PHPGEFOM_00172 5.5e-137 metQ_4 P Belongs to the nlpA lipoprotein family
PHPGEFOM_00173 4.2e-74 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PHPGEFOM_00174 2.4e-259 1.1.3.15 C FAD linked oxidases, C-terminal domain
PHPGEFOM_00175 6e-188 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPGEFOM_00176 1.4e-60 cps2I M Spore coat protein
PHPGEFOM_00177 3e-188 glf 5.4.99.9 M UDP-galactopyranose mutase
PHPGEFOM_00178 2e-17
PHPGEFOM_00179 1.8e-88 M Domain of unknown function (DUF4422)
PHPGEFOM_00180 1.2e-83 pssE S Glycosyltransferase family 28 C-terminal domain
PHPGEFOM_00181 5.2e-86 cpsF M Oligosaccharide biosynthesis protein Alg14 like
PHPGEFOM_00182 5.8e-123 rfbP M Bacterial sugar transferase
PHPGEFOM_00183 7.5e-146 ywqE 3.1.3.48 GM PHP domain protein
PHPGEFOM_00184 9.8e-114 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PHPGEFOM_00185 2.2e-109 epsB M biosynthesis protein
PHPGEFOM_00186 2.1e-175 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PHPGEFOM_00187 3e-224 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PHPGEFOM_00188 1.8e-115 M NlpC P60 family protein
PHPGEFOM_00189 1.2e-123 M NlpC P60 family protein
PHPGEFOM_00190 1.5e-106 M NlpC P60 family protein
PHPGEFOM_00191 1.9e-75 M NlpC/P60 family
PHPGEFOM_00192 1.4e-200 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPGEFOM_00193 5.6e-83 M NlpC P60 family
PHPGEFOM_00194 1.9e-95 gmk2 2.7.4.8 F Guanylate kinase homologues.
PHPGEFOM_00195 7.2e-45
PHPGEFOM_00196 2.9e-290 S O-antigen ligase like membrane protein
PHPGEFOM_00197 2.2e-111
PHPGEFOM_00198 4.1e-76
PHPGEFOM_00199 1.4e-84 S Threonine/Serine exporter, ThrE
PHPGEFOM_00200 2.8e-137 thrE S Putative threonine/serine exporter
PHPGEFOM_00201 9.5e-294 S ABC transporter, ATP-binding protein
PHPGEFOM_00202 2.7e-16
PHPGEFOM_00203 1.1e-206 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PHPGEFOM_00204 4.2e-250 L Putative transposase DNA-binding domain
PHPGEFOM_00205 1.3e-66 E Methionine synthase
PHPGEFOM_00206 2.3e-237 EK Aminotransferase, class I
PHPGEFOM_00207 2.8e-168 K LysR substrate binding domain
PHPGEFOM_00208 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PHPGEFOM_00209 1e-76 argR K Regulates arginine biosynthesis genes
PHPGEFOM_00210 3.1e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PHPGEFOM_00211 2.1e-207 S Amidohydrolase
PHPGEFOM_00212 2.5e-175 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPGEFOM_00213 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PHPGEFOM_00214 3.2e-183 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
PHPGEFOM_00215 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PHPGEFOM_00216 8.1e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PHPGEFOM_00217 0.0 oatA I Acyltransferase
PHPGEFOM_00218 3.7e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PHPGEFOM_00219 4.5e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PHPGEFOM_00220 1e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PHPGEFOM_00221 6.9e-308 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PHPGEFOM_00222 0.0 L SNF2 family N-terminal domain
PHPGEFOM_00223 3.7e-63
PHPGEFOM_00225 3.2e-98 ywlG S Belongs to the UPF0340 family
PHPGEFOM_00226 1.9e-15 gmuR K UTRA
PHPGEFOM_00227 4.4e-55 gmuR K UbiC transcription regulator-associated domain protein
PHPGEFOM_00228 7.6e-89 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PHPGEFOM_00229 4.3e-29 S Protein of unknown function (DUF2929)
PHPGEFOM_00230 0.0 dnaE 2.7.7.7 L DNA polymerase
PHPGEFOM_00231 2e-180 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PHPGEFOM_00232 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PHPGEFOM_00233 5.9e-39 ssuB P anion transmembrane transporter activity
PHPGEFOM_00235 1e-88 I Acyltransferase family
PHPGEFOM_00236 4e-164 cvfB S S1 domain
PHPGEFOM_00237 5.4e-164 xerD D recombinase XerD
PHPGEFOM_00238 8.9e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PHPGEFOM_00239 6e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PHPGEFOM_00240 3.4e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PHPGEFOM_00241 9.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PHPGEFOM_00242 3.9e-117 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PHPGEFOM_00244 5e-108 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PHPGEFOM_00245 3.2e-212 rpsA 1.17.7.4 J Ribosomal protein S1
PHPGEFOM_00246 7.4e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PHPGEFOM_00247 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PHPGEFOM_00248 3.9e-229 S Tetratricopeptide repeat protein
PHPGEFOM_00249 0.0 S Bacterial membrane protein YfhO
PHPGEFOM_00250 2.3e-90 K LysR substrate binding domain
PHPGEFOM_00251 2e-36 K LysR substrate binding domain
PHPGEFOM_00252 1.3e-111 K DNA-binding transcription factor activity
PHPGEFOM_00253 3.4e-26
PHPGEFOM_00254 5.2e-16
PHPGEFOM_00255 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHPGEFOM_00256 7e-71
PHPGEFOM_00258 4.5e-204 argH 2.3.1.1, 4.3.2.1 E argininosuccinate lyase
PHPGEFOM_00260 5e-18
PHPGEFOM_00262 0.0 cas3 L CRISPR-associated helicase cas3
PHPGEFOM_00263 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
PHPGEFOM_00264 1.8e-107 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
PHPGEFOM_00265 1.3e-180 casC L CT1975-like protein
PHPGEFOM_00266 1.6e-131 casD S CRISPR-associated protein (Cas_Cas5)
PHPGEFOM_00267 6.9e-118 casE S CRISPR_assoc
PHPGEFOM_00268 1.2e-174 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PHPGEFOM_00269 1e-159 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
PHPGEFOM_00270 1.2e-109 2.7.6.5 T Region found in RelA / SpoT proteins
PHPGEFOM_00271 7.4e-118 K response regulator
PHPGEFOM_00272 6.7e-229 sptS 2.7.13.3 T Histidine kinase
PHPGEFOM_00273 1.3e-196 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
PHPGEFOM_00274 2.8e-216 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PHPGEFOM_00275 4.8e-221 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PHPGEFOM_00276 2.2e-225 yjjP S Putative threonine/serine exporter
PHPGEFOM_00277 1.1e-89 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PHPGEFOM_00278 4.2e-175 prmA J Ribosomal protein L11 methyltransferase
PHPGEFOM_00279 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHPGEFOM_00280 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PHPGEFOM_00281 2.3e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
PHPGEFOM_00282 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PHPGEFOM_00283 4e-12
PHPGEFOM_00284 1e-276 E Amino acid permease
PHPGEFOM_00285 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
PHPGEFOM_00286 6.2e-81 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
PHPGEFOM_00287 6.5e-127 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
PHPGEFOM_00288 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PHPGEFOM_00289 2.1e-199 pfkA 2.7.1.11, 2.7.1.90 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PHPGEFOM_00290 7.8e-79 2.7.1.199, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHPGEFOM_00291 1.4e-159 scrB 3.2.1.26 GH32 G invertase
PHPGEFOM_00292 3.2e-138 scrR K Transcriptional regulator, LacI family
PHPGEFOM_00293 7.7e-25
PHPGEFOM_00294 1.5e-106 yiiE S Protein of unknown function (DUF1211)
PHPGEFOM_00295 7.2e-100 K Acetyltransferase (GNAT) domain
PHPGEFOM_00299 1.2e-282 thrC 4.2.3.1 E Threonine synthase
PHPGEFOM_00300 7.2e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PHPGEFOM_00301 6.3e-108 galR K Transcriptional regulator
PHPGEFOM_00302 6.6e-26 K purine nucleotide biosynthetic process
PHPGEFOM_00303 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PHPGEFOM_00304 0.0 lacS G Transporter
PHPGEFOM_00305 1.6e-112 P Cobalt transport protein
PHPGEFOM_00306 1.4e-251 cbiO1 S ABC transporter, ATP-binding protein
PHPGEFOM_00307 4.6e-269 emrY EGP Major facilitator Superfamily
PHPGEFOM_00308 2.2e-151 K helix_turn_helix, arabinose operon control protein
PHPGEFOM_00309 9.5e-172 natA1 S ABC transporter
PHPGEFOM_00310 1.6e-108 S ABC-2 family transporter protein
PHPGEFOM_00311 2.5e-138 S ABC-2 family transporter protein
PHPGEFOM_00313 1.3e-221 S ATP diphosphatase activity
PHPGEFOM_00314 1.2e-152 mutR K Helix-turn-helix XRE-family like proteins
PHPGEFOM_00315 4.4e-150 htpX O Belongs to the peptidase M48B family
PHPGEFOM_00316 1.6e-94 lemA S LemA family
PHPGEFOM_00317 5e-207 ybiR P Citrate transporter
PHPGEFOM_00318 2.8e-16
PHPGEFOM_00319 2.2e-173 L HNH nucleases
PHPGEFOM_00320 5e-114 CBM50 M NlpC P60 family protein
PHPGEFOM_00321 3.5e-140 glnQ E ABC transporter, ATP-binding protein
PHPGEFOM_00322 1.9e-273 glnP P ABC transporter permease
PHPGEFOM_00323 9.4e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PHPGEFOM_00324 3.7e-66 yeaO S Protein of unknown function, DUF488
PHPGEFOM_00325 4.2e-132 cobB K SIR2 family
PHPGEFOM_00326 2.3e-81
PHPGEFOM_00327 5.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHPGEFOM_00328 5.6e-180 S Alpha/beta hydrolase of unknown function (DUF915)
PHPGEFOM_00329 5.9e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHPGEFOM_00330 6.3e-163 ypuA S Protein of unknown function (DUF1002)
PHPGEFOM_00331 5.7e-160 epsV 2.7.8.12 S glycosyl transferase family 2
PHPGEFOM_00332 1.1e-124 S Alpha/beta hydrolase family
PHPGEFOM_00333 4.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHPGEFOM_00334 2.4e-124 luxT K Bacterial regulatory proteins, tetR family
PHPGEFOM_00335 1.7e-143
PHPGEFOM_00336 7.2e-118 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PHPGEFOM_00337 5.3e-200 S Cysteine-rich secretory protein family
PHPGEFOM_00338 7.6e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PHPGEFOM_00339 1.8e-44
PHPGEFOM_00340 9.9e-184 yibE S overlaps another CDS with the same product name
PHPGEFOM_00341 4.5e-130 yibF S overlaps another CDS with the same product name
PHPGEFOM_00342 2.4e-169 I alpha/beta hydrolase fold
PHPGEFOM_00343 2.8e-17 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
PHPGEFOM_00344 2.5e-52 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
PHPGEFOM_00345 1.5e-101 malF P Binding-protein-dependent transport system inner membrane component
PHPGEFOM_00346 1.3e-143 malG P ABC transporter permease
PHPGEFOM_00347 0.0 G Belongs to the glycosyl hydrolase 31 family
PHPGEFOM_00348 1.5e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PHPGEFOM_00349 3e-89 ntd 2.4.2.6 F Nucleoside
PHPGEFOM_00350 1.1e-83 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHPGEFOM_00351 1.7e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
PHPGEFOM_00352 2.5e-83 uspA T universal stress protein
PHPGEFOM_00353 2.3e-157 phnD P Phosphonate ABC transporter
PHPGEFOM_00354 3.3e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PHPGEFOM_00355 7.5e-125 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
PHPGEFOM_00356 1.1e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
PHPGEFOM_00357 3.9e-207 oppA E ABC transporter, substratebinding protein
PHPGEFOM_00358 7.1e-28 oppA E ABC transporter, substratebinding protein
PHPGEFOM_00359 6.6e-84
PHPGEFOM_00360 1.7e-273 S Calcineurin-like phosphoesterase
PHPGEFOM_00361 0.0 asnB 6.3.5.4 E Asparagine synthase
PHPGEFOM_00362 7.6e-249 yxbA 6.3.1.12 S ATP-grasp enzyme
PHPGEFOM_00363 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PHPGEFOM_00364 3.9e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHPGEFOM_00365 9.4e-33 S Iron-sulfur cluster assembly protein
PHPGEFOM_00366 3.7e-49 XK27_04775 S PAS domain
PHPGEFOM_00367 1.4e-228 yttB EGP Major facilitator Superfamily
PHPGEFOM_00368 5e-62 Z012_07300 O Glutaredoxin-related protein
PHPGEFOM_00369 0.0 pepO 3.4.24.71 O Peptidase family M13
PHPGEFOM_00370 0.0 kup P Transport of potassium into the cell
PHPGEFOM_00371 1.7e-72
PHPGEFOM_00372 6.2e-86
PHPGEFOM_00373 3.4e-29
PHPGEFOM_00374 4e-34 S Protein of unknown function (DUF2922)
PHPGEFOM_00375 6.3e-192 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PHPGEFOM_00376 5.5e-276 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
PHPGEFOM_00377 0.0 yjbQ P TrkA C-terminal domain protein
PHPGEFOM_00378 9.2e-99 S Oxidoreductase
PHPGEFOM_00379 2e-132
PHPGEFOM_00380 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHPGEFOM_00381 1.7e-206 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PHPGEFOM_00382 2.9e-108 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PHPGEFOM_00383 0.0 XK27_08315 M Sulfatase
PHPGEFOM_00384 1.3e-150 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PHPGEFOM_00385 1.2e-160 spoU 2.1.1.185 J Methyltransferase
PHPGEFOM_00386 1.2e-79 asnB 6.3.5.4 E Aluminium induced protein
PHPGEFOM_00387 1.1e-185 asnB 6.3.5.4 E Aluminium induced protein
PHPGEFOM_00391 1.2e-173
PHPGEFOM_00392 0.0 ydgH S MMPL family
PHPGEFOM_00393 2.3e-99 yobS K Bacterial regulatory proteins, tetR family
PHPGEFOM_00394 5.5e-26
PHPGEFOM_00395 1.7e-157 3.5.2.6 V Beta-lactamase enzyme family
PHPGEFOM_00396 6.7e-154 corA P CorA-like Mg2+ transporter protein
PHPGEFOM_00397 4.6e-176 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
PHPGEFOM_00398 5.4e-86 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PHPGEFOM_00399 5.7e-106
PHPGEFOM_00400 2.6e-42 E dipeptidase activity
PHPGEFOM_00401 3e-124 endA F DNA RNA non-specific endonuclease
PHPGEFOM_00402 1.6e-157 dkg S reductase
PHPGEFOM_00405 3.5e-44 GK ROK family
PHPGEFOM_00406 7.8e-09 S PAS domain
PHPGEFOM_00407 3.3e-289 V ABC transporter transmembrane region
PHPGEFOM_00408 1.9e-77 L COG3547 Transposase and inactivated derivatives
PHPGEFOM_00409 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHPGEFOM_00410 7.4e-166 S Alpha/beta hydrolase of unknown function (DUF915)
PHPGEFOM_00411 4.4e-149 S Sucrose-6F-phosphate phosphohydrolase
PHPGEFOM_00412 3.3e-138 puuD S peptidase C26
PHPGEFOM_00413 5.3e-159 yicL EG EamA-like transporter family
PHPGEFOM_00414 5.7e-49 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
PHPGEFOM_00415 9e-31 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
PHPGEFOM_00416 1.3e-131 C FAD binding domain
PHPGEFOM_00418 2e-132 gph 3.1.3.18 S HAD-hyrolase-like
PHPGEFOM_00419 2.6e-42 yjdJ S GCN5-related N-acetyl-transferase
PHPGEFOM_00421 8.4e-63 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHPGEFOM_00422 2.6e-162 rnhA 3.1.26.4 L Resolvase, N-terminal
PHPGEFOM_00423 2e-18 P Rhodanese Homology Domain
PHPGEFOM_00424 0.0 V ABC transporter transmembrane region
PHPGEFOM_00425 3.4e-308 XK27_09600 V ABC transporter, ATP-binding protein
PHPGEFOM_00426 3.4e-77 K Transcriptional regulator, MarR family
PHPGEFOM_00427 9.1e-164 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPGEFOM_00428 2.9e-78 V Psort location CytoplasmicMembrane, score
PHPGEFOM_00429 4.1e-167 V Psort location CytoplasmicMembrane, score 10.00
PHPGEFOM_00430 5.9e-46 V (ABC) transporter
PHPGEFOM_00431 1.4e-113 ylbE GM NAD(P)H-binding
PHPGEFOM_00432 2.6e-85 S Hydrolases of the alpha beta superfamily
PHPGEFOM_00433 3.1e-57
PHPGEFOM_00434 0.0 yacH D Putative exonuclease SbcCD, C subunit
PHPGEFOM_00437 1.1e-19 S Protein of unknown function N-terminus (DUF3323)
PHPGEFOM_00438 1e-47 GM epimerase
PHPGEFOM_00439 6e-71 K Transcriptional regulator
PHPGEFOM_00440 1.4e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PHPGEFOM_00441 3.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHPGEFOM_00442 4.2e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PHPGEFOM_00443 3.2e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PHPGEFOM_00444 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PHPGEFOM_00445 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PHPGEFOM_00448 1.5e-225 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PHPGEFOM_00449 3.4e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PHPGEFOM_00452 4e-175 lacX 5.1.3.3 G Aldose 1-epimerase
PHPGEFOM_00453 2.4e-243 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PHPGEFOM_00454 4e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PHPGEFOM_00455 1.8e-164 xerC D Phage integrase, N-terminal SAM-like domain
PHPGEFOM_00456 6.8e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PHPGEFOM_00457 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PHPGEFOM_00458 2e-152 dprA LU DNA protecting protein DprA
PHPGEFOM_00459 4.4e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHPGEFOM_00460 7.4e-163 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PHPGEFOM_00461 5.5e-36 yozE S Belongs to the UPF0346 family
PHPGEFOM_00462 3.3e-155 DegV S Uncharacterised protein, DegV family COG1307
PHPGEFOM_00463 4.8e-117 hlyIII S protein, hemolysin III
PHPGEFOM_00464 4.1e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PHPGEFOM_00465 4.3e-169 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHPGEFOM_00466 1.8e-07 yliE T Putative diguanylate phosphodiesterase
PHPGEFOM_00467 3e-09 yliE T EAL domain
PHPGEFOM_00468 1.2e-09 yliE T Putative diguanylate phosphodiesterase
PHPGEFOM_00470 0.0 XK27_10035 V ABC transporter
PHPGEFOM_00471 5.3e-309 yfiB1 V ABC transporter, ATP-binding protein
PHPGEFOM_00472 4.1e-164 lysR7 K LysR substrate binding domain
PHPGEFOM_00473 1.2e-157
PHPGEFOM_00474 1.6e-100 3.6.1.27 I Acid phosphatase homologues
PHPGEFOM_00475 9.8e-152 yitS S Uncharacterised protein, DegV family COG1307
PHPGEFOM_00476 1.7e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHPGEFOM_00477 2.6e-53 S Protein of unknown function (DUF2752)
PHPGEFOM_00478 1.5e-181 yjgN S Bacterial protein of unknown function (DUF898)
PHPGEFOM_00479 1.6e-103 S Protein of unknown function (DUF4230)
PHPGEFOM_00480 2.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PHPGEFOM_00481 1.1e-259 glnPH2 P ABC transporter permease
PHPGEFOM_00482 2.4e-161 lysR5 K LysR substrate binding domain
PHPGEFOM_00483 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
PHPGEFOM_00484 1.2e-103 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PHPGEFOM_00485 6.8e-14 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PHPGEFOM_00486 1.2e-184 S AI-2E family transporter
PHPGEFOM_00487 5.3e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PHPGEFOM_00488 5.9e-155 czcD P cation diffusion facilitator family transporter
PHPGEFOM_00489 2.5e-49 K DNA-binding transcription factor activity
PHPGEFOM_00490 9.1e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PHPGEFOM_00491 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PHPGEFOM_00492 2.1e-123 srtA 3.4.22.70 M sortase family
PHPGEFOM_00493 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PHPGEFOM_00494 1.7e-170 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PHPGEFOM_00495 0.0 dnaK O Heat shock 70 kDa protein
PHPGEFOM_00496 5.7e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PHPGEFOM_00497 8.7e-190 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PHPGEFOM_00498 6.8e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PHPGEFOM_00499 9.9e-100 sip L Belongs to the 'phage' integrase family
PHPGEFOM_00500 2.7e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
PHPGEFOM_00504 2.8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PHPGEFOM_00505 7.2e-162 htrA 3.4.21.107 O serine protease
PHPGEFOM_00506 8.8e-150 vicX 3.1.26.11 S domain protein
PHPGEFOM_00507 4.4e-141 yycI S YycH protein
PHPGEFOM_00508 5e-242 yycH S YycH protein
PHPGEFOM_00509 0.0 vicK 2.7.13.3 T Histidine kinase
PHPGEFOM_00510 2.6e-132 K response regulator
PHPGEFOM_00512 5.5e-149 arbV 2.3.1.51 I Acyl-transferase
PHPGEFOM_00513 3.2e-155 arbx M Glycosyl transferase family 8
PHPGEFOM_00514 1.6e-116 arbY M Glycosyl transferase family 8
PHPGEFOM_00515 2.5e-166 arbZ I Phosphate acyltransferases
PHPGEFOM_00516 0.0 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 C FAD binding domain
PHPGEFOM_00517 1.6e-171 K Transcriptional regulator, LysR family
PHPGEFOM_00518 1.7e-148 ydiN EGP Major Facilitator Superfamily
PHPGEFOM_00519 2.9e-96 S Membrane
PHPGEFOM_00520 1.3e-221 naiP EGP Major facilitator Superfamily
PHPGEFOM_00521 2.4e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PHPGEFOM_00522 7.3e-172 glk 2.7.1.2 G Glucokinase
PHPGEFOM_00524 2.9e-103
PHPGEFOM_00525 6.6e-220 2.1.1.14 E methionine synthase, vitamin-B12 independent
PHPGEFOM_00526 1.5e-161 cpsY K Transcriptional regulator, LysR family
PHPGEFOM_00527 1.2e-129
PHPGEFOM_00528 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PHPGEFOM_00529 6.5e-282 V ABC-type multidrug transport system, ATPase and permease components
PHPGEFOM_00530 3.4e-102 V ABC-type multidrug transport system, ATPase and permease components
PHPGEFOM_00531 1.2e-62 V ABC-type multidrug transport system, ATPase and permease components
PHPGEFOM_00532 3.4e-14 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
PHPGEFOM_00533 1e-184 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
PHPGEFOM_00534 6.6e-119 dedA S SNARE-like domain protein
PHPGEFOM_00535 3.5e-106 S Protein of unknown function (DUF1461)
PHPGEFOM_00536 3.1e-144 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PHPGEFOM_00537 2.8e-83 yutD S Protein of unknown function (DUF1027)
PHPGEFOM_00538 5.6e-280 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PHPGEFOM_00539 5.6e-58
PHPGEFOM_00540 4.9e-182 ccpA K catabolite control protein A
PHPGEFOM_00541 1.8e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PHPGEFOM_00543 1.4e-27 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PHPGEFOM_00544 1.7e-39
PHPGEFOM_00545 5.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PHPGEFOM_00546 2.7e-149 ykuT M mechanosensitive ion channel
PHPGEFOM_00547 2.3e-113 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PHPGEFOM_00548 1.7e-66 yslB S Protein of unknown function (DUF2507)
PHPGEFOM_00549 1e-53 trxA O Belongs to the thioredoxin family
PHPGEFOM_00550 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PHPGEFOM_00551 1e-40 yrzB S Belongs to the UPF0473 family
PHPGEFOM_00552 3.9e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PHPGEFOM_00553 5.7e-42 yrzL S Belongs to the UPF0297 family
PHPGEFOM_00554 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PHPGEFOM_00555 7.5e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PHPGEFOM_00556 4.1e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PHPGEFOM_00557 6.4e-207 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PHPGEFOM_00558 7.9e-282 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PHPGEFOM_00559 3e-34 yajC U Preprotein translocase
PHPGEFOM_00560 1.6e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PHPGEFOM_00561 6.4e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PHPGEFOM_00562 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PHPGEFOM_00563 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PHPGEFOM_00564 1.8e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PHPGEFOM_00565 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PHPGEFOM_00566 1e-122 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PHPGEFOM_00567 6.8e-302 uup S ABC transporter, ATP-binding protein
PHPGEFOM_00568 7.6e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PHPGEFOM_00569 7.7e-94 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PHPGEFOM_00570 3.6e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PHPGEFOM_00571 2e-39 folT S ECF transporter, substrate-specific component
PHPGEFOM_00572 6.3e-165 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PHPGEFOM_00573 1.4e-98 repA S Replication initiator protein A
PHPGEFOM_00574 3.2e-21 U Relaxase/Mobilisation nuclease domain
PHPGEFOM_00575 5.2e-93 mdt(A) EGP Major facilitator Superfamily
PHPGEFOM_00576 0.0 copB 3.6.3.4 P P-type ATPase
PHPGEFOM_00578 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
PHPGEFOM_00579 1.2e-168 ytrB V ABC transporter
PHPGEFOM_00580 0.0 S ABC-type transport system involved in multi-copper enzyme maturation permease component
PHPGEFOM_00581 4.4e-36 cycA E Amino acid permease
PHPGEFOM_00582 7.6e-160 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
PHPGEFOM_00583 1.3e-99 S UPF0397 protein
PHPGEFOM_00584 0.0 ykoD P ABC transporter, ATP-binding protein
PHPGEFOM_00585 4.4e-144 cbiQ P cobalt transport
PHPGEFOM_00586 6.7e-262 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
PHPGEFOM_00587 3.7e-85 S ECF-type riboflavin transporter, S component
PHPGEFOM_00588 4.8e-11 5.99.1.2 T diguanylate cyclase
PHPGEFOM_00589 1.5e-109 T EAL domain
PHPGEFOM_00590 2.5e-28 5.99.1.2 T diguanylate cyclase
PHPGEFOM_00591 7.1e-71 2.7.13.3 T diguanylate cyclase
PHPGEFOM_00592 2.7e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PHPGEFOM_00593 3.2e-212 EGP Transmembrane secretion effector
PHPGEFOM_00594 8.6e-201
PHPGEFOM_00595 8.5e-159 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PHPGEFOM_00596 9.4e-26 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
PHPGEFOM_00597 9.7e-180 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
PHPGEFOM_00598 4.8e-232 6.3.2.4 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PHPGEFOM_00599 1.1e-92 3.6.1.13 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PHPGEFOM_00600 4.2e-264 oppA E ABC transporter, substratebinding protein
PHPGEFOM_00601 8.7e-60 yvoA_1 K Transcriptional regulator, GntR family
PHPGEFOM_00602 1.7e-120 skfE V ATPases associated with a variety of cellular activities
PHPGEFOM_00604 3.3e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PHPGEFOM_00605 7.2e-181 yeiH S Conserved hypothetical protein 698
PHPGEFOM_00606 1.2e-160 K LysR substrate binding domain
PHPGEFOM_00607 2.7e-105 3.6.1.67 F NUDIX domain
PHPGEFOM_00608 1.1e-275 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PHPGEFOM_00609 9.4e-77 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PHPGEFOM_00610 5.5e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHPGEFOM_00611 2.4e-101 yvrI K sigma factor activity
PHPGEFOM_00612 1.8e-33
PHPGEFOM_00613 1.4e-112 4.2.99.20 S Alpha/beta hydrolase family
PHPGEFOM_00614 9.1e-95 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PHPGEFOM_00615 2.9e-96 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PHPGEFOM_00616 6.7e-50 dxs 2.2.1.7 HI 1-deoxy-D-xylulose-5-phosphate synthase
PHPGEFOM_00617 1e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PHPGEFOM_00618 1.8e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PHPGEFOM_00619 5.2e-101 nusG K Participates in transcription elongation, termination and antitermination
PHPGEFOM_00620 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PHPGEFOM_00621 2e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PHPGEFOM_00622 2.9e-190 S Glycosyl transferase family 2
PHPGEFOM_00623 1.6e-230 amtB P ammonium transporter
PHPGEFOM_00624 8.5e-69
PHPGEFOM_00625 1.2e-197
PHPGEFOM_00626 1.1e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
PHPGEFOM_00627 6.2e-76 ymfM S Helix-turn-helix domain
PHPGEFOM_00628 1.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHPGEFOM_00629 1e-170 coaA 2.7.1.33 F Pantothenic acid kinase
PHPGEFOM_00630 5.7e-103 E GDSL-like Lipase/Acylhydrolase
PHPGEFOM_00631 2.6e-74 XK27_02470 K LytTr DNA-binding domain
PHPGEFOM_00632 1.8e-11 liaI S membrane
PHPGEFOM_00633 4.7e-85 aatB ET ABC transporter substrate-binding protein
PHPGEFOM_00634 5.5e-49 aatB ET ABC transporter substrate-binding protein
PHPGEFOM_00635 1.6e-25 glnQ 3.6.3.21 E ABC transporter
PHPGEFOM_00636 0.0 helD 3.6.4.12 L DNA helicase
PHPGEFOM_00637 4.5e-115 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PHPGEFOM_00638 2e-123 pgm3 G Phosphoglycerate mutase family
PHPGEFOM_00639 3.4e-134 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PHPGEFOM_00640 2.5e-39
PHPGEFOM_00642 0.0 3.1.4.46, 3.2.1.99 GH43 N domain, Protein
PHPGEFOM_00643 1.3e-10 sidC L DNA recombination
PHPGEFOM_00644 6.9e-84 sidC L DNA recombination
PHPGEFOM_00645 2.6e-58 sidC L DNA recombination
PHPGEFOM_00646 2.2e-128 S VanZ like family
PHPGEFOM_00647 9.4e-74 mesH S Teichoic acid glycosylation protein
PHPGEFOM_00648 1.9e-74 S VanZ like family
PHPGEFOM_00649 2.5e-27 I transferase activity, transferring acyl groups other than amino-acyl groups
PHPGEFOM_00650 1.1e-49 S Bacterial membrane protein, YfhO
PHPGEFOM_00651 6.2e-09 S Peptidase_C39 like family
PHPGEFOM_00652 2.1e-18 S Peptidase_C39 like family
PHPGEFOM_00653 5.6e-41 I Acyltransferase family
PHPGEFOM_00655 4.7e-222
PHPGEFOM_00656 3.4e-85 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
PHPGEFOM_00657 6e-179 M LicD family
PHPGEFOM_00658 2.1e-263 epsIIL S Membrane protein involved in the export of O-antigen and teichoic acid
PHPGEFOM_00659 5.1e-198 wbbI M transferase activity, transferring glycosyl groups
PHPGEFOM_00660 1.5e-184 M Glycosyl transferases group 1
PHPGEFOM_00661 2.4e-172 glfT1 1.1.1.133 S Glycosyltransferase like family 2
PHPGEFOM_00662 2.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
PHPGEFOM_00663 7.7e-151 cps1D M Domain of unknown function (DUF4422)
PHPGEFOM_00664 2.2e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
PHPGEFOM_00665 1.6e-132 S Core-2/I-Branching enzyme
PHPGEFOM_00666 2.6e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PHPGEFOM_00668 2.9e-71 F DNA/RNA non-specific endonuclease
PHPGEFOM_00669 8.5e-86
PHPGEFOM_00670 2.7e-58 K sequence-specific DNA binding
PHPGEFOM_00671 5e-182 gpsA 1.1.1.94 I Rossmann-like domain
PHPGEFOM_00672 4.5e-40 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PHPGEFOM_00673 1.1e-57 C Coenzyme F420-dependent N5N10-methylene tetrahydromethanopterin reductase
PHPGEFOM_00674 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PHPGEFOM_00675 4e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PHPGEFOM_00676 2.6e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHPGEFOM_00677 1.4e-62 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PHPGEFOM_00678 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PHPGEFOM_00679 3e-243 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PHPGEFOM_00680 5.3e-201 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PHPGEFOM_00681 2.2e-37 yaaA S S4 domain protein YaaA
PHPGEFOM_00682 2.2e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PHPGEFOM_00683 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHPGEFOM_00684 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHPGEFOM_00685 5.1e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
PHPGEFOM_00686 1.4e-88 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PHPGEFOM_00687 3.3e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PHPGEFOM_00688 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PHPGEFOM_00689 1.5e-74 rplI J Binds to the 23S rRNA
PHPGEFOM_00690 9.8e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PHPGEFOM_00691 7.5e-227 MA20_36090 S Protein of unknown function (DUF2974)
PHPGEFOM_00692 0.0 V ATPases associated with a variety of cellular activities
PHPGEFOM_00693 1.1e-68
PHPGEFOM_00695 5.8e-121 yhiD S MgtC family
PHPGEFOM_00697 3.3e-73 V ABC-type multidrug transport system, ATPase and permease components
PHPGEFOM_00698 1.4e-114 V ABC-type multidrug transport system, ATPase and permease components
PHPGEFOM_00699 1.4e-139 K LytTr DNA-binding domain
PHPGEFOM_00700 1.2e-191 2.7.13.3 T GHKL domain
PHPGEFOM_00702 5.4e-25
PHPGEFOM_00703 8.6e-304 msbA2 3.6.3.44 V ABC transporter
PHPGEFOM_00704 0.0 KLT Protein kinase domain
PHPGEFOM_00705 1e-20
PHPGEFOM_00707 2e-112 ybbL S ABC transporter, ATP-binding protein
PHPGEFOM_00708 2.3e-131 ybbM S Uncharacterised protein family (UPF0014)
PHPGEFOM_00709 3.3e-10
PHPGEFOM_00710 7.6e-240 lysA2 M Glycosyl hydrolases family 25
PHPGEFOM_00711 9.4e-11 K Acetyltransferase (GNAT) domain
PHPGEFOM_00712 9.5e-29 K Acetyltransferase (GNAT) domain
PHPGEFOM_00713 4.5e-93 L Psort location Cytoplasmic, score 8.87
PHPGEFOM_00714 1.2e-14 L Transposase
PHPGEFOM_00716 2e-152 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PHPGEFOM_00717 2.9e-91 S ECF-type riboflavin transporter, S component
PHPGEFOM_00718 0.0 L Helicase C-terminal domain protein
PHPGEFOM_00719 4.1e-98 T integral membrane protein
PHPGEFOM_00720 2.3e-84 S YcxB-like protein
PHPGEFOM_00721 1.4e-72 K Transcriptional regulator
PHPGEFOM_00723 3e-56 qorB 1.6.5.2 GM NmrA-like family
PHPGEFOM_00724 1.3e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PHPGEFOM_00727 4.9e-72 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
PHPGEFOM_00728 4.6e-99 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
PHPGEFOM_00729 3.7e-21 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
PHPGEFOM_00730 1.7e-221 oxlT P Major Facilitator Superfamily
PHPGEFOM_00732 7.8e-19 K sequence-specific DNA binding
PHPGEFOM_00733 2.4e-47
PHPGEFOM_00734 0.0 recQ1 L Helicase conserved C-terminal domain
PHPGEFOM_00735 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PHPGEFOM_00736 1.6e-07 K Helix-turn-helix domain
PHPGEFOM_00738 2.5e-163 3.5.2.6 M NlpC/P60 family
PHPGEFOM_00739 8.6e-246 cycA E Amino acid permease
PHPGEFOM_00741 1.6e-63 manO S Domain of unknown function (DUF956)
PHPGEFOM_00742 3.9e-170 manN G system, mannose fructose sorbose family IID component
PHPGEFOM_00743 1.9e-139 manY G PTS system
PHPGEFOM_00744 3.6e-188 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PHPGEFOM_00748 1.3e-30
PHPGEFOM_00750 1.7e-10 S Bacteriophage holin of superfamily 6 (Holin_LLH)
PHPGEFOM_00751 6.6e-88 lysA2 M Glycosyl hydrolases family 25
PHPGEFOM_00752 1.5e-47
PHPGEFOM_00754 6.1e-134 K Transcriptional regulatory protein, C terminal
PHPGEFOM_00755 2e-275 T PhoQ Sensor
PHPGEFOM_00756 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHPGEFOM_00757 3.1e-107 vanZ V VanZ like family
PHPGEFOM_00758 6.2e-257 pgi 5.3.1.9 G Belongs to the GPI family
PHPGEFOM_00759 1.4e-23 oppA E ABC transporter, substratebinding protein
PHPGEFOM_00760 9.4e-178 oppA E ABC transporter, substratebinding protein
PHPGEFOM_00763 7.6e-191 ampC V Beta-lactamase
PHPGEFOM_00764 4.3e-34
PHPGEFOM_00765 7.9e-260 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
PHPGEFOM_00766 1.4e-112 tdk 2.7.1.21 F thymidine kinase
PHPGEFOM_00767 2.1e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PHPGEFOM_00768 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PHPGEFOM_00769 5.4e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PHPGEFOM_00770 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PHPGEFOM_00771 4.2e-127 atpB C it plays a direct role in the translocation of protons across the membrane
PHPGEFOM_00772 3.1e-28 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHPGEFOM_00773 4.2e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PHPGEFOM_00774 3.9e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHPGEFOM_00775 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PHPGEFOM_00776 2.4e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PHPGEFOM_00777 1.3e-247 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PHPGEFOM_00778 1.6e-73 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PHPGEFOM_00779 5.1e-32 ywzB S Protein of unknown function (DUF1146)
PHPGEFOM_00780 6.1e-177 mbl D Cell shape determining protein MreB Mrl
PHPGEFOM_00781 7.4e-48 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PHPGEFOM_00782 1.7e-34 S Protein of unknown function (DUF2969)
PHPGEFOM_00783 2.7e-219 rodA D Belongs to the SEDS family
PHPGEFOM_00784 3e-78 usp6 T universal stress protein
PHPGEFOM_00785 1.3e-42
PHPGEFOM_00786 3.6e-241 rarA L recombination factor protein RarA
PHPGEFOM_00787 3.5e-82 yueI S Protein of unknown function (DUF1694)
PHPGEFOM_00788 1.2e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PHPGEFOM_00789 3.4e-300 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PHPGEFOM_00790 1.4e-217 iscS2 2.8.1.7 E Aminotransferase class V
PHPGEFOM_00791 4.2e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PHPGEFOM_00792 7.8e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PHPGEFOM_00793 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PHPGEFOM_00794 1.2e-233 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PHPGEFOM_00795 6.8e-127 S Haloacid dehalogenase-like hydrolase
PHPGEFOM_00796 2.7e-114 radC L DNA repair protein
PHPGEFOM_00797 2.6e-175 mreB D cell shape determining protein MreB
PHPGEFOM_00798 1.8e-137 mreC M Involved in formation and maintenance of cell shape
PHPGEFOM_00799 1.4e-95 mreD
PHPGEFOM_00801 5.7e-55 S Protein of unknown function (DUF3397)
PHPGEFOM_00802 4.1e-77 mraZ K Belongs to the MraZ family
PHPGEFOM_00803 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PHPGEFOM_00804 4.8e-55 ftsL D Cell division protein FtsL
PHPGEFOM_00805 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PHPGEFOM_00806 2.7e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PHPGEFOM_00807 5.6e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PHPGEFOM_00808 1.2e-208 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PHPGEFOM_00809 1.1e-147 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PHPGEFOM_00810 2.2e-241 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PHPGEFOM_00811 8.6e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PHPGEFOM_00812 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PHPGEFOM_00813 7.6e-46 yggT S YGGT family
PHPGEFOM_00814 8.5e-145 ylmH S S4 domain protein
PHPGEFOM_00815 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PHPGEFOM_00816 1.5e-32 cspA K 'Cold-shock' DNA-binding domain
PHPGEFOM_00817 1.1e-101 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PHPGEFOM_00818 5.4e-19
PHPGEFOM_00819 3.1e-127 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PHPGEFOM_00820 2.8e-213 iscS 2.8.1.7 E Aminotransferase class V
PHPGEFOM_00821 3.2e-56 XK27_04120 S Putative amino acid metabolism
PHPGEFOM_00822 2.1e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PHPGEFOM_00823 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PHPGEFOM_00824 1e-103 S Repeat protein
PHPGEFOM_00825 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PHPGEFOM_00826 5.1e-251 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
PHPGEFOM_00827 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHPGEFOM_00828 2.7e-35 ykzG S Belongs to the UPF0356 family
PHPGEFOM_00829 4.7e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PHPGEFOM_00830 0.0 typA T GTP-binding protein TypA
PHPGEFOM_00831 7.1e-212 ftsW D Belongs to the SEDS family
PHPGEFOM_00832 1.1e-53 ylbG S UPF0298 protein
PHPGEFOM_00833 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PHPGEFOM_00834 9.8e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PHPGEFOM_00835 2.3e-190 ylbL T Belongs to the peptidase S16 family
PHPGEFOM_00836 6.4e-70 comEA L Competence protein ComEA
PHPGEFOM_00837 0.0 comEC S Competence protein ComEC
PHPGEFOM_00838 1.6e-180 holA 2.7.7.7 L DNA polymerase III delta subunit
PHPGEFOM_00839 1.6e-33 rpsT J Binds directly to 16S ribosomal RNA
PHPGEFOM_00840 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PHPGEFOM_00841 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHPGEFOM_00842 4.5e-149
PHPGEFOM_00843 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PHPGEFOM_00844 1.1e-194 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PHPGEFOM_00845 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PHPGEFOM_00846 1.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
PHPGEFOM_00847 4.4e-44 S Protein of unknown function (DUF2974)
PHPGEFOM_00848 3.3e-191 I Protein of unknown function (DUF2974)
PHPGEFOM_00850 2.8e-125 pnb C nitroreductase
PHPGEFOM_00852 0.0 E ABC transporter, substratebinding protein
PHPGEFOM_00853 5.4e-65
PHPGEFOM_00854 2.9e-122 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PHPGEFOM_00855 1.8e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PHPGEFOM_00856 9e-89 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PHPGEFOM_00857 1.9e-38 aha1 P E1-E2 ATPase
PHPGEFOM_00858 0.0 aha1 P E1-E2 ATPase
PHPGEFOM_00859 3.2e-121 metQ2 P Belongs to the nlpA lipoprotein family
PHPGEFOM_00860 5.3e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHPGEFOM_00861 3.4e-113 metI P ABC transporter permease
PHPGEFOM_00862 6.4e-265 frdC 1.3.5.4 C FAD binding domain
PHPGEFOM_00863 6.3e-51 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
PHPGEFOM_00864 9.1e-261 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
PHPGEFOM_00865 2.2e-41 WQ51_05710 S Mitochondrial biogenesis AIM24
PHPGEFOM_00866 2.5e-80 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
PHPGEFOM_00867 1e-69 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
PHPGEFOM_00868 5.6e-81 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
PHPGEFOM_00869 3.7e-102 ybaJ Q Methyltransferase domain
PHPGEFOM_00870 1.3e-36 V (ABC) transporter
PHPGEFOM_00871 0.0 carB 6.3.5.5 F Psort location Cytoplasmic, score 8.87
PHPGEFOM_00872 2.3e-88 carB 6.3.5.5 F Psort location Cytoplasmic, score 8.87
PHPGEFOM_00873 6.6e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PHPGEFOM_00874 8.6e-37 T diguanylate cyclase activity
PHPGEFOM_00876 1.3e-117 V MATE efflux family protein
PHPGEFOM_00877 6.1e-74 V MATE efflux family protein
PHPGEFOM_00878 6.1e-73 prpH 3.1.3.16 K 3.5.2 Transcription regulation
PHPGEFOM_00879 5.1e-15 prpH 3.1.3.16 K 3.5.2 Transcription regulation
PHPGEFOM_00880 6.2e-74 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PHPGEFOM_00881 2.5e-106 L Integrase
PHPGEFOM_00882 5.4e-76 cylB U ABC-2 type transporter
PHPGEFOM_00883 2.7e-76
PHPGEFOM_00884 3.1e-71 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
PHPGEFOM_00885 3.3e-130 cysA V ABC transporter, ATP-binding protein
PHPGEFOM_00886 0.0 V FtsX-like permease family
PHPGEFOM_00887 5.4e-13 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
PHPGEFOM_00888 1.8e-28 K Bacterial regulatory helix-turn-helix protein, lysR family
PHPGEFOM_00889 3.3e-83 1.3.5.4 C FAD binding domain
PHPGEFOM_00890 7.5e-194 1.3.5.4 C FAD binding domain
PHPGEFOM_00891 2.6e-09 S Motility quorum-sensing regulator, toxin of MqsA
PHPGEFOM_00893 3.2e-106 ydaF J Acetyltransferase (GNAT) domain
PHPGEFOM_00894 1.2e-85 ykuL S (CBS) domain
PHPGEFOM_00895 0.0 cadA P P-type ATPase
PHPGEFOM_00896 9.3e-201 napA P Sodium/hydrogen exchanger family
PHPGEFOM_00897 2.9e-122 S CAAX protease self-immunity
PHPGEFOM_00898 2.6e-200 S DUF218 domain
PHPGEFOM_00899 2.7e-194 tcsA S ABC transporter substrate-binding protein PnrA-like
PHPGEFOM_00901 1.1e-66 S Psort location Cytoplasmic, score
PHPGEFOM_00902 7.3e-189 KLT Protein tyrosine kinase
PHPGEFOM_00903 1e-70 S Domain of unknown function (DUF4352)
PHPGEFOM_00904 5e-196 tcsA S ABC transporter substrate-binding protein PnrA-like
PHPGEFOM_00905 2.3e-193 tcsA S ABC transporter substrate-binding protein PnrA-like
PHPGEFOM_00906 2.1e-285 xylG 3.6.3.17 S ABC transporter
PHPGEFOM_00907 6.8e-204 yufP S Belongs to the binding-protein-dependent transport system permease family
PHPGEFOM_00908 2.2e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
PHPGEFOM_00909 2.5e-21 EGP Major facilitator Superfamily
PHPGEFOM_00910 2.4e-158 yeaE S Aldo/keto reductase family
PHPGEFOM_00911 1.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PHPGEFOM_00913 1.2e-13 L PFAM Integrase catalytic region
PHPGEFOM_00915 3.4e-166 3.2.1.17 M peptidoglycan-binding domain-containing protein
PHPGEFOM_00916 8.4e-38
PHPGEFOM_00917 2.6e-123 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PHPGEFOM_00918 1.4e-127 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PHPGEFOM_00919 2.2e-268 glnP P ABC transporter
PHPGEFOM_00920 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PHPGEFOM_00921 3.7e-230 pbuG S permease
PHPGEFOM_00922 4.1e-281 clcA P chloride
PHPGEFOM_00923 5.1e-17 lmrA 3.6.3.44 V ABC transporter
PHPGEFOM_00924 2.3e-70
PHPGEFOM_00925 4.4e-92
PHPGEFOM_00926 1e-114
PHPGEFOM_00927 1.1e-103
PHPGEFOM_00928 9.1e-110 V AAA domain, putative AbiEii toxin, Type IV TA system
PHPGEFOM_00929 1.5e-94
PHPGEFOM_00930 1.4e-139
PHPGEFOM_00931 3.5e-67
PHPGEFOM_00932 1.4e-74
PHPGEFOM_00933 2.8e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PHPGEFOM_00934 1.8e-74
PHPGEFOM_00935 1.1e-28 EGP Major facilitator Superfamily
PHPGEFOM_00936 2.7e-112 EGP Major facilitator Superfamily
PHPGEFOM_00937 4.2e-40 EGP Major facilitator Superfamily
PHPGEFOM_00938 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PHPGEFOM_00939 1.7e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PHPGEFOM_00940 2.5e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PHPGEFOM_00941 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PHPGEFOM_00942 3.4e-247 dnaB L Replication initiation and membrane attachment
PHPGEFOM_00943 1.3e-168 dnaI L Primosomal protein DnaI
PHPGEFOM_00944 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PHPGEFOM_00945 2.9e-42
PHPGEFOM_00946 2.3e-32
PHPGEFOM_00947 1.3e-273 S Archaea bacterial proteins of unknown function
PHPGEFOM_00948 5.4e-113 guaB2 L Resolvase, N terminal domain
PHPGEFOM_00949 3.9e-237 L Putative transposase DNA-binding domain
PHPGEFOM_00950 2.6e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PHPGEFOM_00951 1.8e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PHPGEFOM_00952 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PHPGEFOM_00953 2.3e-212 yqeH S Ribosome biogenesis GTPase YqeH
PHPGEFOM_00954 8.4e-119 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PHPGEFOM_00955 1.9e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PHPGEFOM_00956 1.2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PHPGEFOM_00957 1.9e-214 ylbM S Belongs to the UPF0348 family
PHPGEFOM_00958 8.4e-102 yceD S Uncharacterized ACR, COG1399
PHPGEFOM_00959 2.9e-128 K response regulator
PHPGEFOM_00960 3e-290 arlS 2.7.13.3 T Histidine kinase
PHPGEFOM_00961 4.9e-155 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHPGEFOM_00962 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PHPGEFOM_00963 1.2e-135 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHPGEFOM_00964 2e-61 yodB K Transcriptional regulator, HxlR family
PHPGEFOM_00965 2.1e-199 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PHPGEFOM_00966 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHPGEFOM_00967 2e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHPGEFOM_00968 0.0 S membrane
PHPGEFOM_00969 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PHPGEFOM_00970 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PHPGEFOM_00971 4.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PHPGEFOM_00972 7.7e-115 gluP 3.4.21.105 S Rhomboid family
PHPGEFOM_00973 9.5e-33 yqgQ S Bacterial protein of unknown function (DUF910)
PHPGEFOM_00974 2.6e-70 yqhL P Rhodanese-like protein
PHPGEFOM_00975 3.4e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PHPGEFOM_00976 1.2e-138 ynbB 4.4.1.1 P aluminum resistance
PHPGEFOM_00977 2.8e-257 glnA 6.3.1.2 E glutamine synthetase
PHPGEFOM_00978 8.8e-218 EGP Major facilitator Superfamily
PHPGEFOM_00979 4.5e-64 S Domain of unknown function DUF1828
PHPGEFOM_00980 4.1e-248 nhaC C Na H antiporter NhaC
PHPGEFOM_00982 9.2e-73 cydD V abc transporter atp-binding protein
PHPGEFOM_00983 1.4e-275 sufB O assembly protein SufB
PHPGEFOM_00984 3.3e-74 nifU C SUF system FeS assembly protein, NifU family
PHPGEFOM_00985 1.3e-224 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PHPGEFOM_00986 4e-220 sufD O FeS assembly protein SufD
PHPGEFOM_00987 5.9e-143 sufC O FeS assembly ATPase SufC
PHPGEFOM_00988 6e-91 yjcF S Acetyltransferase (GNAT) domain
PHPGEFOM_00989 0.0 S Predicted membrane protein (DUF2207)
PHPGEFOM_00990 1.2e-183 K AI-2E family transporter
PHPGEFOM_00991 8.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PHPGEFOM_00992 1e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHPGEFOM_00993 7.4e-180 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PHPGEFOM_00994 6.3e-123 IQ reductase
PHPGEFOM_00995 3.9e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PHPGEFOM_00996 1e-68 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PHPGEFOM_00997 1.9e-77 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PHPGEFOM_00998 3.1e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PHPGEFOM_00999 1.4e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PHPGEFOM_01000 6.7e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PHPGEFOM_01001 1.4e-125 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PHPGEFOM_01002 2.6e-123 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PHPGEFOM_01004 6.8e-49 S Domain of Unknown Function with PDB structure (DUF3862)
PHPGEFOM_01007 2.5e-57
PHPGEFOM_01008 1e-57 3.4.22.70 M Sortase family
PHPGEFOM_01009 4.7e-96 M ErfK YbiS YcfS YnhG
PHPGEFOM_01010 3.9e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PHPGEFOM_01011 5.3e-161 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PHPGEFOM_01012 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PHPGEFOM_01013 8.1e-55 yheA S Belongs to the UPF0342 family
PHPGEFOM_01014 3.9e-226 yhaO L Ser Thr phosphatase family protein
PHPGEFOM_01015 0.0 L AAA domain
PHPGEFOM_01016 1.1e-178 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
PHPGEFOM_01017 4.7e-66 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F shikimate kinase activity
PHPGEFOM_01018 9.8e-52 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PHPGEFOM_01019 1.1e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PHPGEFOM_01020 2.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PHPGEFOM_01021 1.2e-132 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PHPGEFOM_01022 5.2e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PHPGEFOM_01023 1.8e-54
PHPGEFOM_01024 1.5e-79 hit FG Scavenger mRNA decapping enzyme C-term binding
PHPGEFOM_01025 1.8e-136 ecsA V ABC transporter, ATP-binding protein
PHPGEFOM_01026 1.1e-217 ecsB U ABC transporter
PHPGEFOM_01027 5.2e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PHPGEFOM_01028 1.2e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PHPGEFOM_01029 3.4e-120 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHPGEFOM_01030 4.4e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PHPGEFOM_01031 2e-112 K Helix-turn-helix domain
PHPGEFOM_01032 5e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PHPGEFOM_01033 4.1e-220 patA 2.6.1.1 E Aminotransferase
PHPGEFOM_01034 3.9e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PHPGEFOM_01035 4.7e-171 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PHPGEFOM_01036 4.4e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PHPGEFOM_01037 1.7e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PHPGEFOM_01038 2.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
PHPGEFOM_01039 2.7e-185 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PHPGEFOM_01040 9.5e-153
PHPGEFOM_01041 7.6e-67 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PHPGEFOM_01042 7.5e-57 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PHPGEFOM_01043 1.4e-158 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PHPGEFOM_01044 3.8e-85 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PHPGEFOM_01045 2.2e-293 ytgP S Polysaccharide biosynthesis protein
PHPGEFOM_01046 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PHPGEFOM_01047 2.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
PHPGEFOM_01048 3.5e-104 dedA 3.1.3.1 S SNARE associated Golgi protein
PHPGEFOM_01049 3.7e-31
PHPGEFOM_01050 4.6e-23
PHPGEFOM_01051 8.8e-70 K GNAT family
PHPGEFOM_01052 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
PHPGEFOM_01053 4e-228 4.4.1.8 E Aminotransferase, class I
PHPGEFOM_01054 1.3e-165 htpX O Peptidase family M48
PHPGEFOM_01055 6.4e-77 1.6.5.2 GM NmrA-like family
PHPGEFOM_01056 3.6e-10 1.6.5.2 GM NAD(P)H-binding
PHPGEFOM_01057 3e-78 K Transcriptional regulator
PHPGEFOM_01058 1.2e-169 E ABC transporter, ATP-binding protein
PHPGEFOM_01059 7.2e-278 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PHPGEFOM_01060 1.2e-266 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
PHPGEFOM_01061 8e-117 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PHPGEFOM_01062 2.1e-137 prsW S Involved in the degradation of specific anti-sigma factors
PHPGEFOM_01063 5.6e-112 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PHPGEFOM_01064 1.3e-25
PHPGEFOM_01065 4.2e-138
PHPGEFOM_01066 1.3e-174
PHPGEFOM_01067 7.8e-266 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
PHPGEFOM_01068 7.1e-158 3.4.17.13 V LD-carboxypeptidase
PHPGEFOM_01070 2.8e-12 D Filamentation induced by cAMP protein fic
PHPGEFOM_01071 1.3e-08 D Filamentation induced by cAMP protein fic
PHPGEFOM_01072 9.8e-77 1.3.5.4 C FMN_bind
PHPGEFOM_01073 3.5e-108 pat 2.3.1.183 M Acetyltransferase (GNAT) domain
PHPGEFOM_01074 2.8e-131 ydcF S Gram-negative-bacterium-type cell wall biogenesis
PHPGEFOM_01075 4.1e-99 yyaQ S YjbR
PHPGEFOM_01076 2.9e-51 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PHPGEFOM_01077 1.1e-203 K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PHPGEFOM_01078 4e-30 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHPGEFOM_01079 2.4e-37 celA 3.2.1.86 GT1 G beta-glucosidase activity
PHPGEFOM_01080 3.2e-50 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PHPGEFOM_01081 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PHPGEFOM_01082 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PHPGEFOM_01083 6.7e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PHPGEFOM_01084 6.8e-136 recO L Involved in DNA repair and RecF pathway recombination
PHPGEFOM_01085 2.8e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PHPGEFOM_01086 2.9e-75 cdd 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PHPGEFOM_01087 6.7e-98 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PHPGEFOM_01088 1.3e-171 phoH T phosphate starvation-inducible protein PhoH
PHPGEFOM_01089 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PHPGEFOM_01090 1.5e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PHPGEFOM_01092 3.8e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHPGEFOM_01093 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PHPGEFOM_01094 1.3e-18 L haloacid dehalogenase-like hydrolase
PHPGEFOM_01095 8.7e-59 S glycolate biosynthetic process
PHPGEFOM_01096 1.8e-161 xth 3.1.11.2 L exodeoxyribonuclease III
PHPGEFOM_01097 2e-80
PHPGEFOM_01098 4.2e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PHPGEFOM_01099 6.7e-164 yvgN C Aldo keto reductase
PHPGEFOM_01100 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
PHPGEFOM_01101 9.7e-203 S Protein of unknown function DUF262
PHPGEFOM_01102 3.3e-306 N Uncharacterized conserved protein (DUF2075)
PHPGEFOM_01103 1.6e-77 1.3.5.4 C FAD binding domain
PHPGEFOM_01104 6.5e-104 1.3.5.4 C FAD binding domain
PHPGEFOM_01105 2.2e-90 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PHPGEFOM_01106 8.9e-26 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PHPGEFOM_01107 1.4e-137 S Peptidase family M23
PHPGEFOM_01108 3.1e-80 mutT 3.6.1.55 F NUDIX domain
PHPGEFOM_01109 2.3e-122 trmK 2.1.1.217 S SAM-dependent methyltransferase
PHPGEFOM_01110 1.8e-150 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PHPGEFOM_01111 4.1e-138 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PHPGEFOM_01112 4.4e-88 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PHPGEFOM_01113 7.3e-23
PHPGEFOM_01114 5.2e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PHPGEFOM_01115 9.8e-160 xerD L Phage integrase, N-terminal SAM-like domain
PHPGEFOM_01116 3.9e-53 S Alpha beta hydrolase
PHPGEFOM_01117 3.8e-21 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PHPGEFOM_01118 2.5e-39 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PHPGEFOM_01119 9.7e-115 dnaD L DnaD domain protein
PHPGEFOM_01120 3.6e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PHPGEFOM_01121 6.8e-150 S Sucrose-6F-phosphate phosphohydrolase
PHPGEFOM_01122 2.1e-70 I Psort location Cytoplasmic, score
PHPGEFOM_01123 1.9e-54 I acetylesterase activity
PHPGEFOM_01124 2.4e-189 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPGEFOM_01125 0.0 dap2 3.4.19.1 E Prolyl oligopeptidase family
PHPGEFOM_01126 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PHPGEFOM_01127 2e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PHPGEFOM_01128 3.2e-106 ypsA S Belongs to the UPF0398 family
PHPGEFOM_01129 1e-57 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PHPGEFOM_01130 3.3e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PHPGEFOM_01131 2e-106 XK27_01810 S Calcineurin-like phosphoesterase
PHPGEFOM_01132 4.4e-67 XK27_01810 S Calcineurin-like phosphoesterase
PHPGEFOM_01133 5.4e-59
PHPGEFOM_01134 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PHPGEFOM_01135 9.3e-72 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PHPGEFOM_01136 1e-170 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PHPGEFOM_01137 3.3e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PHPGEFOM_01138 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
PHPGEFOM_01139 5.6e-43 gcvR T Belongs to the UPF0237 family
PHPGEFOM_01140 2.9e-246 XK27_08635 S UPF0210 protein
PHPGEFOM_01141 3.7e-307 FbpA K Fibronectin-binding protein
PHPGEFOM_01142 6.3e-157 degV S EDD domain protein, DegV family
PHPGEFOM_01143 7.5e-173
PHPGEFOM_01144 4.9e-165 EG EamA-like transporter family
PHPGEFOM_01145 6.1e-120 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPGEFOM_01146 3.3e-86 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHPGEFOM_01147 1.1e-83 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PHPGEFOM_01148 1.1e-84 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PHPGEFOM_01149 1.4e-115 3.1.3.73 G phosphoglycerate mutase
PHPGEFOM_01150 4.7e-13 XK27_06780 V ABC transporter permease
PHPGEFOM_01151 6e-91 C Nitroreductase family
PHPGEFOM_01152 9.8e-60 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PHPGEFOM_01154 5.1e-201 xerS L Belongs to the 'phage' integrase family
PHPGEFOM_01155 2.4e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PHPGEFOM_01156 2.9e-194 S Uncharacterized protein conserved in bacteria (DUF2325)
PHPGEFOM_01157 1.8e-72 S Sel1-like repeats.
PHPGEFOM_01158 1.3e-129 T Diguanylate cyclase, GGDEF domain
PHPGEFOM_01160 6.6e-21 S Domain of unknown function (DUF4343)
PHPGEFOM_01161 6.8e-77 GM NmrA-like family
PHPGEFOM_01162 1.2e-177 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
PHPGEFOM_01163 7.4e-83 S An automated process has identified a potential problem with this gene model
PHPGEFOM_01164 1e-140 S Protein of unknown function (DUF3100)
PHPGEFOM_01165 9.4e-247 3.5.1.47 S Peptidase dimerisation domain
PHPGEFOM_01167 6.3e-08 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
PHPGEFOM_01168 3.9e-262 S Uncharacterised protein family (UPF0236)
PHPGEFOM_01169 5.4e-109 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHPGEFOM_01170 1.3e-61 rplQ J Ribosomal protein L17
PHPGEFOM_01171 7.4e-155 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHPGEFOM_01172 4.4e-163 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHPGEFOM_01173 2.1e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHPGEFOM_01174 6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PHPGEFOM_01175 4.2e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PHPGEFOM_01176 3.9e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
PHPGEFOM_01177 3.5e-23
PHPGEFOM_01178 1.6e-45
PHPGEFOM_01179 6.9e-187 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01180 1.2e-12 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01181 1.6e-119 XK27_07525 3.6.1.55 F NUDIX domain
PHPGEFOM_01182 1.9e-52 EGP Major facilitator Superfamily
PHPGEFOM_01183 9.3e-48 EGP Major facilitator Superfamily
PHPGEFOM_01184 2.5e-91 S Phosphatidylethanolamine-binding protein
PHPGEFOM_01187 8.5e-226 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PHPGEFOM_01188 8.8e-166 pfoS S Phosphotransferase system, EIIC
PHPGEFOM_01191 1.4e-56 oppA2 E ABC transporter, substratebinding protein
PHPGEFOM_01192 2.9e-215
PHPGEFOM_01193 1e-198
PHPGEFOM_01194 3.9e-125 gntR1 K UTRA
PHPGEFOM_01195 9.1e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PHPGEFOM_01196 1.5e-261 epsU S Polysaccharide biosynthesis protein
PHPGEFOM_01197 1.4e-133 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PHPGEFOM_01198 1e-204 csaB M Glycosyl transferases group 1
PHPGEFOM_01199 3.1e-135 M Glycosyltransferase sugar-binding region containing DXD motif
PHPGEFOM_01200 3.3e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PHPGEFOM_01201 0.0 pacL 3.6.3.8 P P-type ATPase
PHPGEFOM_01204 2.7e-111 V ABC transporter
PHPGEFOM_01205 1.8e-89 ydcK S Belongs to the SprT family
PHPGEFOM_01207 4.1e-102 S ECF transporter, substrate-specific component
PHPGEFOM_01208 1.3e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
PHPGEFOM_01209 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PHPGEFOM_01210 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PHPGEFOM_01211 9.2e-193 camS S sex pheromone
PHPGEFOM_01212 1.8e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHPGEFOM_01213 2.1e-266 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PHPGEFOM_01214 3.2e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHPGEFOM_01215 1.5e-169 yegS 2.7.1.107 G Lipid kinase
PHPGEFOM_01216 1.4e-117 S Protein of unknown function (DUF1211)
PHPGEFOM_01217 4.8e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHPGEFOM_01218 2.2e-159 L Mrr N-terminal domain
PHPGEFOM_01219 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
PHPGEFOM_01220 1.6e-56 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PHPGEFOM_01221 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PHPGEFOM_01222 4.3e-33 copZ P Heavy-metal-associated domain
PHPGEFOM_01223 8.3e-47 D Di-iron-containing protein involved in the repair of iron-sulfur clusters
PHPGEFOM_01224 2.8e-100 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
PHPGEFOM_01225 6.9e-240 brnQ U Component of the transport system for branched-chain amino acids
PHPGEFOM_01226 5.3e-124 alkD L DNA alkylation repair enzyme
PHPGEFOM_01227 2.5e-94 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
PHPGEFOM_01228 5.3e-76 T Gaf domain
PHPGEFOM_01229 1.3e-30 yliE T Putative diguanylate phosphodiesterase
PHPGEFOM_01231 1.2e-26 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PHPGEFOM_01232 3.8e-52 ypaA S membrane
PHPGEFOM_01233 1.2e-85 K AsnC family
PHPGEFOM_01234 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PHPGEFOM_01235 2.1e-52 mtlR K transcriptional antiterminator
PHPGEFOM_01237 1.1e-32 mtlD 1.1.1.17 G mannitol metabolic process
PHPGEFOM_01238 5.7e-36 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
PHPGEFOM_01239 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PHPGEFOM_01240 5.5e-167 mleP3 S Membrane transport protein
PHPGEFOM_01241 2.2e-309 ybiT S ABC transporter, ATP-binding protein
PHPGEFOM_01242 5.3e-100 kgtP EGP Sugar (and other) transporter
PHPGEFOM_01243 6.1e-49 kgtP EGP Sugar (and other) transporter
PHPGEFOM_01245 2.6e-56
PHPGEFOM_01246 3.3e-217 mdtG EGP Major facilitator Superfamily
PHPGEFOM_01247 5e-120 ybhL S Belongs to the BI1 family
PHPGEFOM_01248 1.3e-142 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PHPGEFOM_01249 2.2e-281 pipD E Dipeptidase
PHPGEFOM_01250 7.8e-210 pepA E M42 glutamyl aminopeptidase
PHPGEFOM_01251 7e-101 S ABC-type cobalt transport system, permease component
PHPGEFOM_01253 3.7e-111 udk 2.7.1.48 F Zeta toxin
PHPGEFOM_01254 2.5e-118 udk 2.7.1.48 F Zeta toxin
PHPGEFOM_01255 2.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PHPGEFOM_01256 6.4e-151 glnH ET ABC transporter substrate-binding protein
PHPGEFOM_01257 5.5e-110 gluC P ABC transporter permease
PHPGEFOM_01258 4.4e-110 glnP P ABC transporter permease
PHPGEFOM_01259 9.6e-155 glnH ET Bacterial periplasmic substrate-binding proteins
PHPGEFOM_01260 9.7e-283 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PHPGEFOM_01261 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PHPGEFOM_01262 1.1e-269 S Uncharacterized protein conserved in bacteria (DUF2252)
PHPGEFOM_01263 7.4e-10 S Protein of unknown function (DUF2974)
PHPGEFOM_01264 5.9e-88
PHPGEFOM_01265 1.5e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PHPGEFOM_01266 2e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PHPGEFOM_01267 5.5e-124 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PHPGEFOM_01268 1.6e-174 rihB 3.2.2.1 F Nucleoside
PHPGEFOM_01269 1.2e-129 gntR K UbiC transcription regulator-associated domain protein
PHPGEFOM_01270 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PHPGEFOM_01272 2.9e-21 3.4.22.70 M Sortase family
PHPGEFOM_01273 2.1e-249 yhdP S Transporter associated domain
PHPGEFOM_01274 9.8e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PHPGEFOM_01275 6.4e-227 potE E amino acid
PHPGEFOM_01276 2.3e-122 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
PHPGEFOM_01277 2.9e-208 yfmL 3.6.4.13 L DEAD DEAH box helicase
PHPGEFOM_01278 1.2e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHPGEFOM_01280 4.7e-183 pfoS S Phosphotransferase system, EIIC
PHPGEFOM_01281 1e-232 pyrP F Permease
PHPGEFOM_01282 1.1e-228 ynbB 4.4.1.1 P aluminum resistance
PHPGEFOM_01283 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
PHPGEFOM_01285 4.1e-270 E Amino acid permease
PHPGEFOM_01286 1.4e-24
PHPGEFOM_01287 1.2e-211 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PHPGEFOM_01288 3.3e-51 gtcA S Teichoic acid glycosylation protein
PHPGEFOM_01289 2.9e-78 fld C Flavodoxin
PHPGEFOM_01290 3.6e-162 map 3.4.11.18 E Methionine Aminopeptidase
PHPGEFOM_01291 4.5e-166 yihY S Belongs to the UPF0761 family
PHPGEFOM_01292 3e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PHPGEFOM_01293 2.8e-18
PHPGEFOM_01294 6.2e-182 D Alpha beta
PHPGEFOM_01295 1.1e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHPGEFOM_01296 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
PHPGEFOM_01297 4.5e-85
PHPGEFOM_01298 1.7e-73
PHPGEFOM_01299 1.2e-157 hlyX S Transporter associated domain
PHPGEFOM_01300 1.6e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PHPGEFOM_01301 2.5e-26
PHPGEFOM_01302 6.2e-205 mco Q Multicopper oxidase
PHPGEFOM_01303 5e-26 mco Q Multicopper oxidase
PHPGEFOM_01304 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
PHPGEFOM_01305 0.0 clpE O Belongs to the ClpA ClpB family
PHPGEFOM_01306 5.8e-10
PHPGEFOM_01307 1.2e-39 ptsH G phosphocarrier protein HPR
PHPGEFOM_01308 2.1e-302 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PHPGEFOM_01309 5e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PHPGEFOM_01310 5.2e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PHPGEFOM_01311 4.4e-163 coiA 3.6.4.12 S Competence protein
PHPGEFOM_01312 3.4e-112 yjbH Q Thioredoxin
PHPGEFOM_01313 3.3e-109 yjbK S CYTH
PHPGEFOM_01314 3.1e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
PHPGEFOM_01315 3.9e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PHPGEFOM_01316 8.2e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PHPGEFOM_01317 2.8e-22
PHPGEFOM_01318 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PHPGEFOM_01319 1.1e-197 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PHPGEFOM_01320 1.3e-93 sip L Belongs to the 'phage' integrase family
PHPGEFOM_01321 1.5e-07 K Helix-turn-helix domain
PHPGEFOM_01323 1.9e-18
PHPGEFOM_01325 9.8e-22 S Primase alpha helix C-terminal domain protein
PHPGEFOM_01326 7e-76 S Virulence-associated protein E
PHPGEFOM_01331 3.5e-64 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PHPGEFOM_01332 2.1e-181 yubA S AI-2E family transporter
PHPGEFOM_01333 8.7e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PHPGEFOM_01334 1.9e-68 WQ51_03320 S Protein of unknown function (DUF1149)
PHPGEFOM_01335 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PHPGEFOM_01336 3.5e-230 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
PHPGEFOM_01337 3.9e-237 S Peptidase M16
PHPGEFOM_01338 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
PHPGEFOM_01339 2.7e-107 ymfM S Helix-turn-helix domain
PHPGEFOM_01340 2.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PHPGEFOM_01341 4.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PHPGEFOM_01342 5.1e-221 rny S Endoribonuclease that initiates mRNA decay
PHPGEFOM_01343 3.1e-215 tagO 2.7.8.33, 2.7.8.35 M transferase
PHPGEFOM_01344 4.7e-117 yvyE 3.4.13.9 S YigZ family
PHPGEFOM_01345 2.7e-246 comFA L Helicase C-terminal domain protein
PHPGEFOM_01346 1.9e-121 comFC S Competence protein
PHPGEFOM_01347 1.6e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PHPGEFOM_01348 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHPGEFOM_01349 5.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PHPGEFOM_01350 9.1e-31
PHPGEFOM_01351 1.2e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PHPGEFOM_01352 2.9e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PHPGEFOM_01353 6.5e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PHPGEFOM_01354 4.9e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PHPGEFOM_01355 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PHPGEFOM_01356 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PHPGEFOM_01357 7.4e-92 S Short repeat of unknown function (DUF308)
PHPGEFOM_01358 4.4e-146 E D-aminopeptidase
PHPGEFOM_01359 3e-81 dmpA 3.4.11.19 EQ Peptidase family S58
PHPGEFOM_01360 2.4e-164 rapZ S Displays ATPase and GTPase activities
PHPGEFOM_01361 5e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PHPGEFOM_01362 3.4e-169 whiA K May be required for sporulation
PHPGEFOM_01363 5.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PHPGEFOM_01364 1.1e-37
PHPGEFOM_01365 6.1e-213
PHPGEFOM_01367 1.2e-54 ABC-SBP S ABC transporter
PHPGEFOM_01368 1.6e-10 ABC-SBP S ABC transporter
PHPGEFOM_01369 3.8e-144 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PHPGEFOM_01370 5.3e-136 XK27_08845 S ABC transporter, ATP-binding protein
PHPGEFOM_01372 1.8e-212 cggR K Putative sugar-binding domain
PHPGEFOM_01373 3.8e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PHPGEFOM_01374 3e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PHPGEFOM_01375 2.9e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PHPGEFOM_01376 8.3e-26 3.2.2.20 K acetyltransferase
PHPGEFOM_01377 8.6e-50 3.2.2.20 K acetyltransferase
PHPGEFOM_01378 8e-105
PHPGEFOM_01379 2.6e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
PHPGEFOM_01380 1.5e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PHPGEFOM_01381 9.7e-183 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PHPGEFOM_01382 4.2e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PHPGEFOM_01383 1.2e-97 dnaQ 2.7.7.7 L DNA polymerase III
PHPGEFOM_01384 2.9e-162 murB 1.3.1.98 M Cell wall formation
PHPGEFOM_01385 1.4e-203 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PHPGEFOM_01386 1.1e-144 potB P ABC transporter permease
PHPGEFOM_01387 5.6e-128 potC P ABC transporter permease
PHPGEFOM_01388 2.4e-206 potD P ABC transporter
PHPGEFOM_01389 4.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PHPGEFOM_01390 4.4e-73 ybbR S YbbR-like protein
PHPGEFOM_01391 2.5e-63 ybbR S YbbR-like protein
PHPGEFOM_01392 5.3e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PHPGEFOM_01393 6.8e-150 S hydrolase
PHPGEFOM_01394 2e-55 V peptidase activity
PHPGEFOM_01395 1.4e-77 atkY K Copper transport repressor CopY TcrY
PHPGEFOM_01396 6.5e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PHPGEFOM_01397 0.0 copA 3.6.3.54 P P-type ATPase
PHPGEFOM_01398 4.2e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHPGEFOM_01399 5e-60 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHPGEFOM_01400 5.2e-33
PHPGEFOM_01401 2.5e-49
PHPGEFOM_01402 6.1e-197 yliE T EAL domain
PHPGEFOM_01403 5e-265 T Diguanylate cyclase, GGDEF domain
PHPGEFOM_01404 1.5e-25
PHPGEFOM_01405 1.2e-65
PHPGEFOM_01406 6.3e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PHPGEFOM_01407 7.2e-68 GM epimerase
PHPGEFOM_01408 0.0 E Amino acid permease
PHPGEFOM_01409 2.2e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHPGEFOM_01410 8.9e-158 rssA S Phospholipase, patatin family
PHPGEFOM_01411 1.2e-163 psaA P Belongs to the bacterial solute-binding protein 9 family
PHPGEFOM_01412 2e-94 S VanZ like family
PHPGEFOM_01413 1.4e-130 yebC K Transcriptional regulatory protein
PHPGEFOM_01414 4.4e-180 comGA NU Type II IV secretion system protein
PHPGEFOM_01415 4.9e-158 comGB NU type II secretion system
PHPGEFOM_01416 6.5e-51 comGC U competence protein ComGC
PHPGEFOM_01417 2.3e-75
PHPGEFOM_01419 1.9e-11 comGF U Putative Competence protein ComGF
PHPGEFOM_01420 2.8e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
PHPGEFOM_01421 2.6e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHPGEFOM_01423 5.3e-104 S Protein of unknown function (DUF3644)
PHPGEFOM_01424 2.1e-189 S Phage integrase family
PHPGEFOM_01425 3.4e-24 S Domain of Unknown Function with PDB structure (DUF3862)
PHPGEFOM_01426 9.5e-11 E Zn peptidase
PHPGEFOM_01427 4.4e-37 ansR 3.4.21.88 K sequence-specific DNA binding
PHPGEFOM_01432 1.8e-130 S AAA domain
PHPGEFOM_01433 2.1e-117 res L Helicase C-terminal domain protein
PHPGEFOM_01434 8.3e-80 S Protein of unknown function (DUF669)
PHPGEFOM_01435 0.0 S Phage plasmid primase, P4
PHPGEFOM_01436 3.2e-54 S VRR-NUC domain
PHPGEFOM_01437 2.2e-09
PHPGEFOM_01442 1.8e-81
PHPGEFOM_01443 4e-40 L Terminase small subunit
PHPGEFOM_01444 4.3e-156 S Terminase-like family
PHPGEFOM_01445 1.4e-177 S Phage portal protein, SPP1 Gp6-like
PHPGEFOM_01446 5.9e-90 S Phage Mu protein F like protein
PHPGEFOM_01447 5.2e-37 S Phage minor structural protein GP20
PHPGEFOM_01448 7.2e-103
PHPGEFOM_01449 2.2e-21
PHPGEFOM_01450 7.5e-32
PHPGEFOM_01451 4e-26 S Bacteriophage HK97-gp10, putative tail-component
PHPGEFOM_01452 4.2e-10
PHPGEFOM_01454 7.2e-112 S Phage tail sheath protein
PHPGEFOM_01455 2e-45 S Protein of unknown function (DUF2001)
PHPGEFOM_01456 4.3e-31 xkdN S Phage XkdN-like tail assembly chaperone protein, TAC
PHPGEFOM_01457 1.2e-97 S phage tail tape measure protein
PHPGEFOM_01458 2.6e-30 ygaU GH23 S protein containing LysM domain
PHPGEFOM_01459 3.8e-61 yqbQ G PFAM Phage late control gene D protein (GPD)
PHPGEFOM_01460 9e-27 S Protein of unknown function (DUF2577)
PHPGEFOM_01461 3.6e-23 S Protein of unknown function (DUF2634)
PHPGEFOM_01462 7.3e-105 xkdT S Baseplate J-like protein
PHPGEFOM_01463 1.7e-24 S Uncharacterised protein conserved in bacteria (DUF2313)
PHPGEFOM_01464 1.3e-107 pncA Q Isochorismatase family
PHPGEFOM_01465 1.1e-106
PHPGEFOM_01466 2e-42 L Membrane
PHPGEFOM_01467 7.5e-146 2.7.7.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
PHPGEFOM_01468 7.6e-252 L Putative transposase DNA-binding domain
PHPGEFOM_01469 4.1e-41 S Enterocin A Immunity
PHPGEFOM_01471 2.9e-116 E peptidase
PHPGEFOM_01472 5e-137 V ABC-2 type transporter
PHPGEFOM_01473 1.5e-129 V ATPases associated with a variety of cellular activities
PHPGEFOM_01474 5e-75 KLT Protein kinase domain
PHPGEFOM_01475 1.1e-118
PHPGEFOM_01477 3.3e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PHPGEFOM_01478 1.8e-89 comEB 3.5.4.12 F MafB19-like deaminase
PHPGEFOM_01479 1.2e-103 S TPM domain
PHPGEFOM_01480 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
PHPGEFOM_01481 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PHPGEFOM_01482 3.3e-149 tatD L hydrolase, TatD family
PHPGEFOM_01483 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PHPGEFOM_01484 6.8e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PHPGEFOM_01485 6.4e-38 veg S Biofilm formation stimulator VEG
PHPGEFOM_01486 1.6e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PHPGEFOM_01487 4e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PHPGEFOM_01488 6.8e-43
PHPGEFOM_01489 6.7e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHPGEFOM_01490 2.8e-254 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
PHPGEFOM_01491 2.5e-65 S Domain of unknown function (DUF1934)
PHPGEFOM_01492 1.1e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PHPGEFOM_01493 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PHPGEFOM_01494 1.9e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHPGEFOM_01495 1.6e-41 rpmE2 J Ribosomal protein L31
PHPGEFOM_01496 2.7e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PHPGEFOM_01497 8.2e-239 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PHPGEFOM_01498 9.4e-71 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PHPGEFOM_01499 2.6e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PHPGEFOM_01500 2e-126 S (CBS) domain
PHPGEFOM_01501 1.1e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PHPGEFOM_01502 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PHPGEFOM_01503 3.2e-34 yabO J S4 domain protein
PHPGEFOM_01504 1.5e-59 divIC D Septum formation initiator
PHPGEFOM_01505 7.5e-61 yabR J S1 RNA binding domain
PHPGEFOM_01506 2.7e-249 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PHPGEFOM_01507 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PHPGEFOM_01508 5.3e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PHPGEFOM_01509 5e-301 E ABC transporter, substratebinding protein
PHPGEFOM_01510 1.3e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PHPGEFOM_01511 1.1e-197 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHPGEFOM_01512 2.5e-278 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PHPGEFOM_01514 6.6e-139 T diguanylate cyclase activity
PHPGEFOM_01516 4.1e-22 metY 2.5.1.49 E o-acetylhomoserine
PHPGEFOM_01517 1.1e-217 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
PHPGEFOM_01518 1.1e-107 XK27_00160 S Domain of unknown function (DUF5052)
PHPGEFOM_01522 1.3e-81 yebR 1.8.4.14 T GAF domain-containing protein
PHPGEFOM_01523 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PHPGEFOM_01526 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHPGEFOM_01527 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHPGEFOM_01528 9e-08 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PHPGEFOM_01531 1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PHPGEFOM_01532 3.5e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PHPGEFOM_01533 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PHPGEFOM_01534 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PHPGEFOM_01535 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PHPGEFOM_01536 1.6e-106 rplD J Forms part of the polypeptide exit tunnel
PHPGEFOM_01537 8.3e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PHPGEFOM_01538 2.8e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PHPGEFOM_01539 4.5e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PHPGEFOM_01540 8.9e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PHPGEFOM_01541 9.4e-121 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PHPGEFOM_01542 1.9e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PHPGEFOM_01543 3.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
PHPGEFOM_01544 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PHPGEFOM_01545 1.6e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PHPGEFOM_01546 4.5e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PHPGEFOM_01547 9.3e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PHPGEFOM_01548 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PHPGEFOM_01549 2.8e-91 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PHPGEFOM_01550 5.7e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PHPGEFOM_01551 1.3e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PHPGEFOM_01552 1.3e-24 rpmD J Ribosomal protein L30
PHPGEFOM_01553 1.8e-72 rplO J Binds to the 23S rRNA
PHPGEFOM_01554 1.1e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PHPGEFOM_01555 5.9e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PHPGEFOM_01556 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PHPGEFOM_01557 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PHPGEFOM_01558 1.4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PHPGEFOM_01559 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PHPGEFOM_01560 4.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PHPGEFOM_01561 7.4e-32 S Uncharacterised protein family (UPF0236)
PHPGEFOM_01562 3.9e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PHPGEFOM_01563 7e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PHPGEFOM_01564 8.4e-54 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
PHPGEFOM_01565 1.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PHPGEFOM_01566 5.5e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PHPGEFOM_01567 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PHPGEFOM_01568 4.8e-42 rplGA J ribosomal protein
PHPGEFOM_01569 4.3e-43 ylxR K Protein of unknown function (DUF448)
PHPGEFOM_01570 6.8e-194 nusA K Participates in both transcription termination and antitermination
PHPGEFOM_01571 1.9e-83 rimP J Required for maturation of 30S ribosomal subunits
PHPGEFOM_01572 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHPGEFOM_01573 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PHPGEFOM_01574 4.3e-228 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PHPGEFOM_01575 1.1e-144 cdsA 2.7.7.41 S Belongs to the CDS family
PHPGEFOM_01576 7.6e-124 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PHPGEFOM_01577 2.9e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PHPGEFOM_01578 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PHPGEFOM_01579 5.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PHPGEFOM_01580 1.1e-136 rpsB J Belongs to the universal ribosomal protein uS2 family
PHPGEFOM_01581 7.1e-189 yabB 2.1.1.223 L Methyltransferase small domain
PHPGEFOM_01582 1.4e-115 plsC 2.3.1.51 I Acyltransferase
PHPGEFOM_01583 4.8e-182 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PHPGEFOM_01584 1.3e-251 yclM 2.7.2.4 E Belongs to the aspartokinase family
PHPGEFOM_01585 3.6e-213 hom 1.1.1.3 E homoserine dehydrogenase
PHPGEFOM_01586 2.6e-71 pheB 5.4.99.5 S Belongs to the UPF0735 family
PHPGEFOM_01587 0.0 mdlB V ABC transporter
PHPGEFOM_01588 0.0 mdlA V ABC transporter
PHPGEFOM_01589 2.3e-31 yneF S Uncharacterised protein family (UPF0154)
PHPGEFOM_01590 8.9e-34 ynzC S UPF0291 protein
PHPGEFOM_01591 3.5e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PHPGEFOM_01592 6e-149 glcU U ribose uptake protein RbsU
PHPGEFOM_01593 9.6e-145 glnH ET ABC transporter substrate-binding protein
PHPGEFOM_01594 3.4e-97
PHPGEFOM_01595 0.0 lhr L DEAD DEAH box helicase
PHPGEFOM_01596 4.9e-246 P P-loop Domain of unknown function (DUF2791)
PHPGEFOM_01597 0.0 S TerB-C domain
PHPGEFOM_01598 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
PHPGEFOM_01599 5.5e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PHPGEFOM_01600 0.0 snf 2.7.11.1 KL domain protein
PHPGEFOM_01601 1.8e-09 CP_1020 S Psort location Cytoplasmic, score 8.87
PHPGEFOM_01602 1.4e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PHPGEFOM_01603 1.5e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PHPGEFOM_01604 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PHPGEFOM_01605 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PHPGEFOM_01606 8.6e-54 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PHPGEFOM_01607 1.5e-73 pipD E Dipeptidase
PHPGEFOM_01608 1.1e-07 pipD E Dipeptidase
PHPGEFOM_01609 1.7e-15 pipD E Dipeptidase
PHPGEFOM_01611 7.5e-154 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PHPGEFOM_01612 0.0 smc D Required for chromosome condensation and partitioning
PHPGEFOM_01613 3.1e-127 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PHPGEFOM_01614 0.0 oppA E ABC transporter substrate-binding protein
PHPGEFOM_01615 0.0 oppA1 E ABC transporter substrate-binding protein
PHPGEFOM_01616 1.3e-157 oppC P Binding-protein-dependent transport system inner membrane component
PHPGEFOM_01617 1.3e-176 oppB P ABC transporter permease
PHPGEFOM_01618 2.4e-178 oppF P Belongs to the ABC transporter superfamily
PHPGEFOM_01619 1.4e-189 oppD P Belongs to the ABC transporter superfamily
PHPGEFOM_01620 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHPGEFOM_01621 7.5e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PHPGEFOM_01622 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PHPGEFOM_01623 1.6e-278 yloV S DAK2 domain fusion protein YloV
PHPGEFOM_01624 8.8e-57 asp S Asp23 family, cell envelope-related function
PHPGEFOM_01625 3.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PHPGEFOM_01626 3e-279 V ABC transporter transmembrane region
PHPGEFOM_01629 1.8e-30 D nuclear chromosome segregation
PHPGEFOM_01631 1.4e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
PHPGEFOM_01632 1.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PHPGEFOM_01633 0.0 KLT serine threonine protein kinase
PHPGEFOM_01634 4.3e-138 stp 3.1.3.16 T phosphatase
PHPGEFOM_01635 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PHPGEFOM_01636 1.1e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PHPGEFOM_01637 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PHPGEFOM_01638 2.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PHPGEFOM_01639 1.1e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
PHPGEFOM_01640 2.6e-49
PHPGEFOM_01641 3.2e-33 oppA E transmembrane transport
PHPGEFOM_01642 2.9e-14 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01643 1.6e-46 oppA E transmembrane transport
PHPGEFOM_01644 1.4e-306 recN L May be involved in recombinational repair of damaged DNA
PHPGEFOM_01645 7.8e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PHPGEFOM_01646 5.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PHPGEFOM_01647 1.7e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHPGEFOM_01648 8e-252 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHPGEFOM_01649 3.7e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PHPGEFOM_01650 1.8e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PHPGEFOM_01651 8.1e-73 yqhY S Asp23 family, cell envelope-related function
PHPGEFOM_01652 2.4e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHPGEFOM_01653 1.1e-195 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PHPGEFOM_01654 2.1e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PHPGEFOM_01655 9.9e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PHPGEFOM_01656 3.9e-65 arsC 1.20.4.1 P Belongs to the ArsC family
PHPGEFOM_01657 4e-90 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PHPGEFOM_01658 2.6e-60 livF E ABC transporter
PHPGEFOM_01659 3.1e-242 purD 6.3.4.13 F Belongs to the GARS family
PHPGEFOM_01660 3.3e-283 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PHPGEFOM_01661 1.4e-109 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PHPGEFOM_01662 4.6e-199 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PHPGEFOM_01663 6.6e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PHPGEFOM_01664 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHPGEFOM_01665 5.2e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHPGEFOM_01666 2.8e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHPGEFOM_01667 1.6e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PHPGEFOM_01668 4.4e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PHPGEFOM_01669 1.6e-210 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PHPGEFOM_01670 1.1e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PHPGEFOM_01671 4.8e-41 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
PHPGEFOM_01672 4.2e-119 EGP Major Facilitator Superfamily
PHPGEFOM_01673 5.4e-98 P nitrite transmembrane transporter activity
PHPGEFOM_01674 1e-234
PHPGEFOM_01675 1.3e-308 S SH3-like domain
PHPGEFOM_01676 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
PHPGEFOM_01678 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PHPGEFOM_01679 1.3e-216 EGP Major facilitator Superfamily
PHPGEFOM_01680 6.9e-25 bgl 3.2.1.21, 3.2.1.86 GT1 G beta-glucosidase activity
PHPGEFOM_01681 8.1e-190 manA 5.3.1.8 G mannose-6-phosphate isomerase
PHPGEFOM_01682 3.7e-28 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PHPGEFOM_01683 3.5e-18 yliE T EAL domain
PHPGEFOM_01684 3.9e-139
PHPGEFOM_01686 3.9e-84 K DNA-templated transcription, initiation
PHPGEFOM_01687 4.2e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PHPGEFOM_01688 5.7e-167 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
PHPGEFOM_01689 0.0 S Bacterial membrane protein, YfhO
PHPGEFOM_01690 1.3e-179 yfdH GT2 M Glycosyltransferase like family 2
PHPGEFOM_01691 5.5e-92 racA K Domain of unknown function (DUF1836)
PHPGEFOM_01692 1.7e-151 yitS S EDD domain protein, DegV family
PHPGEFOM_01693 1.1e-103 T EAL domain
PHPGEFOM_01694 1.2e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
PHPGEFOM_01695 4.7e-125 gpmB G Phosphoglycerate mutase family
PHPGEFOM_01696 8.1e-13
PHPGEFOM_01697 1.1e-119
PHPGEFOM_01698 1.3e-42
PHPGEFOM_01699 2e-89 S biotin transmembrane transporter activity
PHPGEFOM_01701 5.3e-164 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
PHPGEFOM_01702 1.3e-50 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PHPGEFOM_01703 3e-142 G polysaccharide deacetylase
PHPGEFOM_01704 3.8e-10 G polysaccharide deacetylase
PHPGEFOM_01705 2.7e-83 M LysM domain protein
PHPGEFOM_01706 9.5e-145 D nuclear chromosome segregation
PHPGEFOM_01707 8e-252 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
PHPGEFOM_01708 3.4e-08 lacR K DeoR C terminal sensor domain
PHPGEFOM_01709 1.4e-165 cycA E Amino acid permease
PHPGEFOM_01710 1.7e-47 cycA E Amino acid permease
PHPGEFOM_01711 1.4e-275 pepV 3.5.1.18 E dipeptidase PepV
PHPGEFOM_01712 1.8e-136 ybbH_2 K Helix-turn-helix domain, rpiR family
PHPGEFOM_01713 1e-18 3.5.2.6 V Beta-lactamase
PHPGEFOM_01714 7.5e-08 3.5.2.6 V Beta-lactamase
PHPGEFOM_01715 4.8e-196 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
PHPGEFOM_01716 1.7e-93 wecD K Acetyltransferase (GNAT) family
PHPGEFOM_01717 1e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PHPGEFOM_01718 8.5e-115 S membrane transporter protein
PHPGEFOM_01719 4.7e-128 pgm3 G Belongs to the phosphoglycerate mutase family
PHPGEFOM_01720 2.6e-28
PHPGEFOM_01721 5.2e-29
PHPGEFOM_01722 2.2e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHPGEFOM_01723 2.1e-79 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PHPGEFOM_01724 7e-183 S AAA domain
PHPGEFOM_01725 8.1e-57 5.2.1.8 O Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
PHPGEFOM_01726 3.2e-51 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
PHPGEFOM_01727 2.1e-32 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
PHPGEFOM_01729 1.9e-43 V AAA domain (dynein-related subfamily)
PHPGEFOM_01730 2.1e-44 S LlaJI restriction endonuclease
PHPGEFOM_01731 5.6e-266 pepC 3.4.22.40 E Peptidase C1-like family
PHPGEFOM_01732 5.4e-49
PHPGEFOM_01733 1.7e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PHPGEFOM_01734 6.6e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PHPGEFOM_01735 9e-186 arbY M Glycosyl transferase family 8
PHPGEFOM_01736 7.8e-64 yliE T domain protein
PHPGEFOM_01737 2.1e-149 yliE T Putative diguanylate phosphodiesterase
PHPGEFOM_01739 7.8e-202 S amidohydrolase
PHPGEFOM_01740 1e-13 XK27_07210 6.1.1.6 S B3 4 domain
PHPGEFOM_01741 2.3e-124 E Arginine ornithine antiporter
PHPGEFOM_01742 4.2e-82 E amino acid
PHPGEFOM_01769 1.8e-119 V ABC transporter, ATP-binding protein
PHPGEFOM_01770 1.9e-215 S FtsX-like permease family
PHPGEFOM_01773 8e-79 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PHPGEFOM_01774 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PHPGEFOM_01775 2.9e-29 secG U Preprotein translocase
PHPGEFOM_01776 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHPGEFOM_01777 3.3e-178 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHPGEFOM_01778 2.2e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
PHPGEFOM_01779 2.6e-219 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
PHPGEFOM_01781 1.4e-98 3.6.1.55, 3.6.1.67 F NUDIX domain
PHPGEFOM_01782 6e-112 papP P ABC transporter, permease protein
PHPGEFOM_01783 4e-79 P ABC transporter permease
PHPGEFOM_01784 1.5e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PHPGEFOM_01785 2.7e-160 cjaA ET ABC transporter substrate-binding protein
PHPGEFOM_01788 1.8e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PHPGEFOM_01790 2.3e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
PHPGEFOM_01791 4.8e-86 steT E amino acid
PHPGEFOM_01792 2.1e-232 amd 3.5.1.47 E Peptidase family M20/M25/M40
PHPGEFOM_01793 1.6e-243 N Uncharacterized conserved protein (DUF2075)
PHPGEFOM_01794 3.1e-121 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PHPGEFOM_01795 4e-19 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01796 9.1e-62 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01797 2.3e-173 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01798 9.4e-292 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01799 1.9e-30 oppA E transmembrane transport
PHPGEFOM_01800 3.5e-123 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01801 1.4e-97 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01802 3e-301 oppA E ABC transporter
PHPGEFOM_01803 2.6e-145 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHPGEFOM_01804 7.8e-183 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHPGEFOM_01805 3.9e-198 oppD P Belongs to the ABC transporter superfamily
PHPGEFOM_01806 2.8e-179 oppF P Belongs to the ABC transporter superfamily
PHPGEFOM_01807 5.1e-256 pepC 3.4.22.40 E aminopeptidase
PHPGEFOM_01808 6.5e-259 pepC 3.4.22.40 E Papain family cysteine protease
PHPGEFOM_01809 2.1e-73 hsp O Belongs to the small heat shock protein (HSP20) family
PHPGEFOM_01810 2.1e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHPGEFOM_01811 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PHPGEFOM_01812 3.1e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHPGEFOM_01813 8e-145 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PHPGEFOM_01814 1.7e-96 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PHPGEFOM_01815 2.1e-61
PHPGEFOM_01816 2.1e-225 pbuX F xanthine permease
PHPGEFOM_01817 1.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PHPGEFOM_01818 3.1e-204 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHPGEFOM_01819 2.4e-300 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PHPGEFOM_01820 3.4e-39 S HicA toxin of bacterial toxin-antitoxin,
PHPGEFOM_01821 5.8e-64 S HicB family
PHPGEFOM_01822 1.9e-233 KLT Protein kinase domain
PHPGEFOM_01823 5.7e-169 KLT Protein kinase domain
PHPGEFOM_01824 3.2e-284 V ABC-type multidrug transport system, ATPase and permease components
PHPGEFOM_01825 1.4e-142 K Transcriptional regulator
PHPGEFOM_01826 1.6e-242 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PHPGEFOM_01828 1.1e-15 S Psort location Cytoplasmic, score
PHPGEFOM_01831 3.8e-132 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PHPGEFOM_01832 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PHPGEFOM_01833 1.8e-72 tcyB E ABC transporter
PHPGEFOM_01834 4.8e-42 tcyB E ABC transporter
PHPGEFOM_01836 7.4e-130 2.4.2.3 F Phosphorylase superfamily
PHPGEFOM_01837 2.4e-250 yxbA 6.3.1.12 S ATP-grasp enzyme
PHPGEFOM_01838 1.2e-166 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
PHPGEFOM_01839 5.8e-20 mmuP E amino acid
PHPGEFOM_01840 8.6e-156 mmuP E amino acid
PHPGEFOM_01841 9.2e-175 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PHPGEFOM_01842 8.6e-78 ywhH S Aminoacyl-tRNA editing domain
PHPGEFOM_01843 2.8e-07 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Maltose acetyltransferase
PHPGEFOM_01844 2.1e-76 K DNA-binding transcription factor activity
PHPGEFOM_01845 4.6e-188 ansA 3.5.1.1 EJ L-asparaginase, type I
PHPGEFOM_01846 3.8e-47 Q phosphatase activity
PHPGEFOM_01847 1.1e-92 S Sucrose-6F-phosphate phosphohydrolase
PHPGEFOM_01848 2.6e-80 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PHPGEFOM_01849 3.4e-269 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHPGEFOM_01850 7.6e-92 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01851 1.2e-74 oppA E ABC transporter, substratebinding protein
PHPGEFOM_01852 2e-36
PHPGEFOM_01853 2.5e-129 yliE T Putative diguanylate phosphodiesterase
PHPGEFOM_01856 1.7e-154 pstS P Phosphate
PHPGEFOM_01857 4.3e-161 pstC P probably responsible for the translocation of the substrate across the membrane
PHPGEFOM_01858 2.8e-157 pstA P Phosphate transport system permease protein PstA
PHPGEFOM_01859 3.2e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHPGEFOM_01860 2e-112 phoU P Plays a role in the regulation of phosphate uptake
PHPGEFOM_01861 1.4e-124 T Transcriptional regulatory protein, C terminal
PHPGEFOM_01862 4.1e-303 phoR 2.7.13.3 T Histidine kinase
PHPGEFOM_01863 2.4e-21 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PHPGEFOM_01864 3.3e-32 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PHPGEFOM_01865 8.4e-16 lsa S ABC transporter
PHPGEFOM_01866 3.2e-65 lsa S ABC transporter
PHPGEFOM_01868 7e-121 3.6.1.13 L NUDIX domain
PHPGEFOM_01869 3e-47 S Glycosyl hydrolases family 18
PHPGEFOM_01870 7.6e-129 S Glycosyl hydrolases family 18
PHPGEFOM_01871 6.6e-104 I NUDIX domain
PHPGEFOM_01872 1.5e-101 S C4-dicarboxylate anaerobic carrier
PHPGEFOM_01873 7.2e-141 cbiO2 P ABC transporter
PHPGEFOM_01874 3.8e-148 P ABC transporter
PHPGEFOM_01875 7.8e-135 cbiQ P Cobalt transport protein
PHPGEFOM_01876 8.4e-103 2.7.7.65 T phosphorelay sensor kinase activity
PHPGEFOM_01878 5e-71 yliE T Putative diguanylate phosphodiesterase
PHPGEFOM_01879 4e-209 yliE T Putative diguanylate phosphodiesterase
PHPGEFOM_01880 2.5e-189 2.7.7.65 T diguanylate cyclase
PHPGEFOM_01881 9e-104
PHPGEFOM_01882 5e-153 supH G Sucrose-6F-phosphate phosphohydrolase
PHPGEFOM_01883 5.7e-15 K Winged helix DNA-binding domain
PHPGEFOM_01884 8.3e-48 lmrA V (ABC) transporter
PHPGEFOM_01886 1e-41 V ABC transporter, ATP-binding protein
PHPGEFOM_01887 2.8e-52 V abc transporter atp-binding protein
PHPGEFOM_01888 2.1e-185 yfiC V ABC transporter
PHPGEFOM_01889 7.6e-31 yfiC V ABC transporter
PHPGEFOM_01890 1.3e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PHPGEFOM_01891 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHPGEFOM_01892 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHPGEFOM_01893 1.4e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
PHPGEFOM_01894 3.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PHPGEFOM_01895 4.2e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PHPGEFOM_01896 7.7e-177 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PHPGEFOM_01897 3.7e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
PHPGEFOM_01898 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PHPGEFOM_01899 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PHPGEFOM_01900 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PHPGEFOM_01901 1.2e-59 ypmB S Protein conserved in bacteria

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)