ORF_ID e_value Gene_name EC_number CAZy COGs Description
GBEEKLPO_00001 2e-258 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GBEEKLPO_00002 2.6e-135 parB K Belongs to the ParB family
GBEEKLPO_00003 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
GBEEKLPO_00004 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GBEEKLPO_00005 6.2e-120 yoaK S Protein of unknown function (DUF1275)
GBEEKLPO_00009 0.0 XK27_10405 S Bacterial membrane protein YfhO
GBEEKLPO_00010 5.1e-306 ybiT S abc transporter atp-binding protein
GBEEKLPO_00011 2.2e-154 yvjA S membrane
GBEEKLPO_00012 2.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
GBEEKLPO_00013 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GBEEKLPO_00014 1e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GBEEKLPO_00015 3.1e-60 yaaA S S4 domain protein YaaA
GBEEKLPO_00016 4.8e-235 ymfF S Peptidase M16
GBEEKLPO_00017 2.8e-243 ymfH S Peptidase M16
GBEEKLPO_00018 3.3e-134 S sequence-specific DNA binding
GBEEKLPO_00019 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GBEEKLPO_00020 1.3e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GBEEKLPO_00021 1.6e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GBEEKLPO_00022 6.3e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GBEEKLPO_00023 5.7e-74 lytE M LysM domain protein
GBEEKLPO_00024 5.8e-73 isaA GH23 M Immunodominant staphylococcal antigen A
GBEEKLPO_00025 0.0 S Bacterial membrane protein, YfhO
GBEEKLPO_00026 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GBEEKLPO_00027 2.4e-99 yvbG U UPF0056 membrane protein
GBEEKLPO_00028 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GBEEKLPO_00029 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GBEEKLPO_00030 2.2e-73 rplI J binds to the 23S rRNA
GBEEKLPO_00031 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GBEEKLPO_00032 1.8e-47 veg S Biofilm formation stimulator VEG
GBEEKLPO_00033 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GBEEKLPO_00034 1.9e-10
GBEEKLPO_00035 4.1e-54 ypaA M Membrane
GBEEKLPO_00036 9.9e-97 XK27_06935 K transcriptional regulator
GBEEKLPO_00037 8.1e-159 XK27_06930 V domain protein
GBEEKLPO_00038 3.6e-109 S Putative adhesin
GBEEKLPO_00039 2e-63 XK27_06920 S Protein of unknown function (DUF1700)
GBEEKLPO_00040 6.3e-54 K transcriptional regulator, PadR family
GBEEKLPO_00041 1.5e-117 nudL L hydrolase
GBEEKLPO_00043 1.3e-237 L Transposase
GBEEKLPO_00044 2e-285 K transcriptional regulator containing an HTH domain and an
GBEEKLPO_00045 1.2e-65
GBEEKLPO_00047 2.6e-13
GBEEKLPO_00048 2.2e-62
GBEEKLPO_00049 6.3e-201 L Replication initiation factor
GBEEKLPO_00051 3.6e-282 L DNA integration
GBEEKLPO_00052 3e-232
GBEEKLPO_00053 8.8e-128 P ATPases associated with a variety of cellular activities
GBEEKLPO_00054 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GBEEKLPO_00055 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GBEEKLPO_00056 1.5e-219 metE 2.1.1.14 E Methionine synthase
GBEEKLPO_00057 6.3e-241 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GBEEKLPO_00058 7e-242 hisS 6.1.1.21 J histidyl-tRNA synthetase
GBEEKLPO_00060 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GBEEKLPO_00061 6.4e-168 XK27_01785 S cog cog1284
GBEEKLPO_00062 1.5e-124 yaaA S Belongs to the UPF0246 family
GBEEKLPO_00063 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GBEEKLPO_00064 2e-91 XK27_10930 K acetyltransferase
GBEEKLPO_00065 7.5e-14
GBEEKLPO_00066 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GBEEKLPO_00067 3.1e-298 ccs S the current gene model (or a revised gene model) may contain a frame shift
GBEEKLPO_00068 3.2e-44 yrzB S Belongs to the UPF0473 family
GBEEKLPO_00069 2.3e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GBEEKLPO_00070 6.3e-44 yrzL S Belongs to the UPF0297 family
GBEEKLPO_00071 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GBEEKLPO_00072 2.6e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
GBEEKLPO_00074 4.5e-216 int L Belongs to the 'phage' integrase family
GBEEKLPO_00075 1.9e-18 S Domain of unknown function (DUF3173)
GBEEKLPO_00076 3.8e-155 L Replication initiation factor
GBEEKLPO_00077 3.8e-90 K Cro/C1-type HTH DNA-binding domain
GBEEKLPO_00078 4.2e-173 yeiH S membrane
GBEEKLPO_00080 6.7e-95 adk 2.7.4.3 F topology modulation protein
GBEEKLPO_00081 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GBEEKLPO_00082 1.4e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GBEEKLPO_00083 9.7e-36 XK27_09805 S MORN repeat protein
GBEEKLPO_00084 0.0 XK27_09800 I Acyltransferase
GBEEKLPO_00085 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GBEEKLPO_00086 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
GBEEKLPO_00087 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GBEEKLPO_00088 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
GBEEKLPO_00089 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GBEEKLPO_00090 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GBEEKLPO_00091 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GBEEKLPO_00092 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GBEEKLPO_00093 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GBEEKLPO_00094 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GBEEKLPO_00095 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
GBEEKLPO_00096 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GBEEKLPO_00097 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GBEEKLPO_00098 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GBEEKLPO_00099 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GBEEKLPO_00100 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GBEEKLPO_00101 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GBEEKLPO_00102 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GBEEKLPO_00103 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GBEEKLPO_00104 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GBEEKLPO_00105 1.9e-23 rpmD J ribosomal protein l30
GBEEKLPO_00106 5.7e-58 rplO J binds to the 23S rRNA
GBEEKLPO_00107 3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GBEEKLPO_00108 2.5e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GBEEKLPO_00109 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GBEEKLPO_00110 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GBEEKLPO_00111 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GBEEKLPO_00112 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GBEEKLPO_00113 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBEEKLPO_00114 4.4e-62 rplQ J ribosomal protein l17
GBEEKLPO_00115 1.5e-252 6.3.2.2 H gamma-glutamylcysteine synthetase
GBEEKLPO_00117 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
GBEEKLPO_00120 5.1e-96 ywlG S Belongs to the UPF0340 family
GBEEKLPO_00121 3.2e-127 treR K trehalose operon
GBEEKLPO_00122 0.0 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GBEEKLPO_00123 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
GBEEKLPO_00124 0.0 pepO 3.4.24.71 O Peptidase family M13
GBEEKLPO_00125 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GBEEKLPO_00126 1.9e-88 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_00129 1.1e-278 thrC 4.2.3.1 E Threonine synthase
GBEEKLPO_00130 3.2e-226 norN V Mate efflux family protein
GBEEKLPO_00131 1.4e-57 asp S cog cog1302
GBEEKLPO_00132 3.8e-304 yloV S kinase related to dihydroxyacetone kinase
GBEEKLPO_00133 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GBEEKLPO_00134 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
GBEEKLPO_00135 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
GBEEKLPO_00136 3e-195 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GBEEKLPO_00137 1.9e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GBEEKLPO_00138 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GBEEKLPO_00139 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBEEKLPO_00140 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GBEEKLPO_00141 1e-68 S cog cog4699
GBEEKLPO_00142 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GBEEKLPO_00143 1.4e-145 cglB U protein transport across the cell outer membrane
GBEEKLPO_00144 2.2e-43 comGC U Required for transformation and DNA binding
GBEEKLPO_00145 6.4e-70 cglD NU Competence protein
GBEEKLPO_00146 3.1e-15 NU Type II secretory pathway pseudopilin
GBEEKLPO_00147 5.3e-72 comGF U Competence protein ComGF
GBEEKLPO_00148 5.8e-12 comGF U Putative Competence protein ComGF
GBEEKLPO_00149 7.7e-177 ytxK 2.1.1.72 L DNA methylase
GBEEKLPO_00150 1.4e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GBEEKLPO_00151 8.8e-27 lanR K sequence-specific DNA binding
GBEEKLPO_00152 2.5e-110 V CAAX protease self-immunity
GBEEKLPO_00154 2.7e-112 S CAAX amino terminal protease family protein
GBEEKLPO_00155 6.1e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GBEEKLPO_00156 1.3e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
GBEEKLPO_00157 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
GBEEKLPO_00158 9.4e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GBEEKLPO_00159 7.6e-09 S NTF2 fold immunity protein
GBEEKLPO_00160 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GBEEKLPO_00161 4.7e-120 S CAAX protease self-immunity
GBEEKLPO_00162 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GBEEKLPO_00163 1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GBEEKLPO_00167 1.2e-160 rrmA 2.1.1.187 Q methyltransferase
GBEEKLPO_00168 1.8e-141 S HAD hydrolase, family IA, variant
GBEEKLPO_00169 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GBEEKLPO_00170 7.1e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GBEEKLPO_00171 2.8e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GBEEKLPO_00172 1.5e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
GBEEKLPO_00173 6.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GBEEKLPO_00174 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GBEEKLPO_00175 1.1e-98 XK27_08585 S Psort location CytoplasmicMembrane, score
GBEEKLPO_00176 5.1e-142 fnt P Formate nitrite transporter
GBEEKLPO_00177 2.1e-230 XK27_09615 C reductase
GBEEKLPO_00178 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
GBEEKLPO_00179 5.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
GBEEKLPO_00180 6.4e-77 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GBEEKLPO_00181 1.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GBEEKLPO_00182 1.8e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
GBEEKLPO_00183 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
GBEEKLPO_00184 1.2e-50 S Protein of unknown function (DUF3397)
GBEEKLPO_00185 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GBEEKLPO_00186 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GBEEKLPO_00187 0.0 amiA E ABC transporter, substrate-binding protein, family 5
GBEEKLPO_00188 3.5e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GBEEKLPO_00189 6.7e-232 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
GBEEKLPO_00190 3.7e-157 hpk9 2.7.13.3 T protein histidine kinase activity
GBEEKLPO_00191 7.1e-210 hpk9 2.7.13.3 T protein histidine kinase activity
GBEEKLPO_00192 4.5e-244 fasC 2.7.13.3 T protein histidine kinase activity
GBEEKLPO_00193 2.8e-134 fasA KT Response regulator of the LytR AlgR family
GBEEKLPO_00194 3.4e-154 L PFAM Integrase, catalytic core
GBEEKLPO_00195 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GBEEKLPO_00196 2.4e-264 argH 4.3.2.1 E Argininosuccinate lyase
GBEEKLPO_00197 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GBEEKLPO_00198 1.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GBEEKLPO_00199 1.5e-181 jag S RNA-binding protein
GBEEKLPO_00200 6.9e-107 K Transcriptional regulator
GBEEKLPO_00201 1.5e-103 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
GBEEKLPO_00202 3.4e-14 rpmH J Ribosomal protein L34
GBEEKLPO_00203 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GBEEKLPO_00204 1.5e-236 L Transposase
GBEEKLPO_00207 2.6e-55 bta 1.8.1.8 CO cell redox homeostasis
GBEEKLPO_00208 8.2e-59 L thioesterase
GBEEKLPO_00209 1.5e-250 L Transposase
GBEEKLPO_00210 6e-143 S Macro domain protein
GBEEKLPO_00211 6.3e-51 trxA O Belongs to the thioredoxin family
GBEEKLPO_00212 2.5e-74 yccU S CoA-binding protein
GBEEKLPO_00213 6.6e-145 tatD L Hydrolase, tatd
GBEEKLPO_00214 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GBEEKLPO_00215 3.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GBEEKLPO_00217 4e-164 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GBEEKLPO_00218 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GBEEKLPO_00219 1.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
GBEEKLPO_00220 3.8e-171 rmuC S RmuC domain protein
GBEEKLPO_00221 1.1e-178 cbf S 3'-5' exoribonuclease yhaM
GBEEKLPO_00222 5.3e-142 purR 2.4.2.7 F operon repressor
GBEEKLPO_00223 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GBEEKLPO_00224 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GBEEKLPO_00225 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GBEEKLPO_00226 7.9e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GBEEKLPO_00227 2.7e-126
GBEEKLPO_00228 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GBEEKLPO_00229 2.3e-87 S Fusaric acid resistance protein-like
GBEEKLPO_00230 6.5e-63 glnR K Transcriptional regulator
GBEEKLPO_00231 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
GBEEKLPO_00232 6.6e-116 pscB M CHAP domain protein
GBEEKLPO_00233 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GBEEKLPO_00234 1.5e-33 ykzG S Belongs to the UPF0356 family
GBEEKLPO_00235 4.8e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
GBEEKLPO_00236 2.4e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GBEEKLPO_00237 1.5e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GBEEKLPO_00238 6.7e-114 azlC E AzlC protein
GBEEKLPO_00239 2.2e-46 azlD S branched-chain amino acid
GBEEKLPO_00240 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GBEEKLPO_00241 6.7e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GBEEKLPO_00242 4.8e-157 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GBEEKLPO_00243 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GBEEKLPO_00244 6.1e-94 cvpA S toxin biosynthetic process
GBEEKLPO_00245 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GBEEKLPO_00246 6e-129 V ABC transporter, ATP-binding protein
GBEEKLPO_00247 1e-108 V efflux transmembrane transporter activity
GBEEKLPO_00248 5.6e-187 V ABC transporter (Permease
GBEEKLPO_00250 0.0 V ABC transporter (Permease
GBEEKLPO_00251 3.7e-277 2.7.13.3 T Histidine kinase
GBEEKLPO_00252 1.8e-94 salR K helix_turn_helix, Lux Regulon
GBEEKLPO_00253 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GBEEKLPO_00254 1.3e-37
GBEEKLPO_00255 4.8e-07
GBEEKLPO_00257 6.1e-229 mutY L A G-specific adenine glycosylase
GBEEKLPO_00258 5.5e-42 XK27_05745
GBEEKLPO_00259 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
GBEEKLPO_00260 4.3e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GBEEKLPO_00261 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GBEEKLPO_00263 7e-124 XK27_01040 S Protein of unknown function (DUF1129)
GBEEKLPO_00264 1e-168 corA P COG0598 Mg2 and Co2 transporters
GBEEKLPO_00265 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GBEEKLPO_00269 4.7e-32 blpT
GBEEKLPO_00270 1.7e-188 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
GBEEKLPO_00271 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
GBEEKLPO_00272 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GBEEKLPO_00273 1.7e-61 yqhY S protein conserved in bacteria
GBEEKLPO_00274 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GBEEKLPO_00275 3.4e-180 scrR K purine nucleotide biosynthetic process
GBEEKLPO_00276 2.7e-290 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
GBEEKLPO_00277 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GBEEKLPO_00278 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
GBEEKLPO_00279 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
GBEEKLPO_00281 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GBEEKLPO_00282 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GBEEKLPO_00283 6.2e-207 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GBEEKLPO_00284 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GBEEKLPO_00285 3.1e-206 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GBEEKLPO_00286 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GBEEKLPO_00287 4.7e-160 V ABC transporter
GBEEKLPO_00288 6.6e-123
GBEEKLPO_00292 2.9e-31 yozG K Transcriptional regulator
GBEEKLPO_00294 1.1e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GBEEKLPO_00295 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
GBEEKLPO_00296 1.5e-129 yebC M Membrane
GBEEKLPO_00297 0.0 KT response to antibiotic
GBEEKLPO_00298 6.8e-75 XK27_02470 K LytTr DNA-binding domain protein
GBEEKLPO_00299 5.2e-122 liaI S membrane
GBEEKLPO_00300 9.2e-300 O MreB/Mbl protein
GBEEKLPO_00302 5.8e-146 V Psort location CytoplasmicMembrane, score
GBEEKLPO_00305 8.9e-14
GBEEKLPO_00306 3.8e-243 dcuS 2.7.13.3 T protein histidine kinase activity
GBEEKLPO_00307 1e-246 2.7.13.3 T protein histidine kinase activity
GBEEKLPO_00308 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GBEEKLPO_00309 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GBEEKLPO_00310 7.3e-127 S Protein of unknown function (DUF554)
GBEEKLPO_00311 8.1e-134 ecsA_2 V abc transporter atp-binding protein
GBEEKLPO_00312 9.5e-289 XK27_00765
GBEEKLPO_00313 5.2e-142 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GBEEKLPO_00314 1.5e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GBEEKLPO_00315 4.3e-65 yhaI S Protein of unknown function (DUF805)
GBEEKLPO_00316 5e-69 yhaI J Protein of unknown function (DUF805)
GBEEKLPO_00319 3.7e-25
GBEEKLPO_00321 6.7e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GBEEKLPO_00322 2.4e-45 ftsL D cell division protein FtsL
GBEEKLPO_00323 0.0 ftsI 3.4.16.4 M penicillin-binding protein
GBEEKLPO_00324 3.7e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GBEEKLPO_00325 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GBEEKLPO_00328 9.6e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
GBEEKLPO_00329 1.7e-62 yutD J protein conserved in bacteria
GBEEKLPO_00330 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GBEEKLPO_00331 1.3e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
GBEEKLPO_00334 0.0 mdlA V abc transporter atp-binding protein
GBEEKLPO_00335 0.0 mdlB V abc transporter atp-binding protein
GBEEKLPO_00336 1.1e-25 S Bacteriocin class II with double-glycine leader peptide
GBEEKLPO_00340 2.7e-228 blpH 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
GBEEKLPO_00341 1.3e-134 agrA KT LytTr DNA-binding domain
GBEEKLPO_00343 5.4e-44 spiA K sequence-specific DNA binding
GBEEKLPO_00347 5.2e-77 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_00348 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GBEEKLPO_00349 1.2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
GBEEKLPO_00350 7e-108 V CAAX protease self-immunity
GBEEKLPO_00351 3.2e-141 cppA E CppA N-terminal
GBEEKLPO_00352 1.6e-179 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
GBEEKLPO_00354 5.2e-77 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_00355 9.4e-80 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBEEKLPO_00356 1.6e-148 cah 4.2.1.1 P carbonic anhydrase
GBEEKLPO_00357 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
GBEEKLPO_00359 0.0 pflB 2.3.1.54 C formate acetyltransferase'
GBEEKLPO_00360 6.2e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBEEKLPO_00361 3.6e-35
GBEEKLPO_00362 3e-153 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
GBEEKLPO_00363 1.9e-15 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
GBEEKLPO_00364 6.1e-163 yxeN P ABC transporter (Permease
GBEEKLPO_00365 1.4e-130 tcyN 3.6.3.21 E abc transporter atp-binding protein
GBEEKLPO_00366 5e-10 S Protein of unknown function (DUF4059)
GBEEKLPO_00367 1.7e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GBEEKLPO_00368 2.9e-105 rsmD 2.1.1.171 L Methyltransferase
GBEEKLPO_00369 1e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GBEEKLPO_00370 4.2e-187 ylbL T Belongs to the peptidase S16 family
GBEEKLPO_00371 8.4e-184 yhcC S radical SAM protein
GBEEKLPO_00372 2e-97 ytqB 2.1.1.176 J (SAM)-dependent
GBEEKLPO_00374 0.0 yjcE P NhaP-type Na H and K H antiporters
GBEEKLPO_00375 4.1e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
GBEEKLPO_00376 1.5e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
GBEEKLPO_00377 5.2e-08 MU outer membrane autotransporter barrel domain protein
GBEEKLPO_00378 3.9e-158 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GBEEKLPO_00380 9e-75 XK27_03180 T universal stress protein
GBEEKLPO_00381 3.1e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
GBEEKLPO_00382 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GBEEKLPO_00383 6.8e-101 pncA Q isochorismatase
GBEEKLPO_00384 1e-294 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GBEEKLPO_00385 7.6e-58 tagE 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
GBEEKLPO_00386 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBEEKLPO_00387 2.2e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GBEEKLPO_00388 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GBEEKLPO_00389 1.4e-65
GBEEKLPO_00390 1.6e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GBEEKLPO_00391 4.7e-99 yqeG S hydrolase of the HAD superfamily
GBEEKLPO_00392 2.9e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GBEEKLPO_00393 7.7e-49 yhbY J RNA-binding protein
GBEEKLPO_00394 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GBEEKLPO_00395 3.6e-108 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
GBEEKLPO_00396 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GBEEKLPO_00397 1.3e-139 yqeM Q Methyltransferase domain protein
GBEEKLPO_00398 3.8e-204 ylbM S Belongs to the UPF0348 family
GBEEKLPO_00399 3.4e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
GBEEKLPO_00400 1.2e-44 yoeB S Addiction module toxin, Txe YoeB family
GBEEKLPO_00401 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
GBEEKLPO_00403 2.5e-104
GBEEKLPO_00405 7.4e-09
GBEEKLPO_00406 1.7e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GBEEKLPO_00407 2.3e-133 ecsA V abc transporter atp-binding protein
GBEEKLPO_00408 1.1e-179 ecsB U Bacterial ABC transporter protein EcsB
GBEEKLPO_00409 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
GBEEKLPO_00410 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GBEEKLPO_00412 1.6e-224 ytfP S Flavoprotein
GBEEKLPO_00413 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GBEEKLPO_00414 1.3e-63 XK27_02560 S cog cog2151
GBEEKLPO_00415 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
GBEEKLPO_00416 9.8e-106 dnaQ 2.7.7.7 L DNA polymerase III
GBEEKLPO_00417 2.9e-131 K transcriptional regulator, MerR family
GBEEKLPO_00418 0.0 V ABC transporter (Permease
GBEEKLPO_00419 3.9e-125 V abc transporter atp-binding protein
GBEEKLPO_00421 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GBEEKLPO_00422 9.5e-49
GBEEKLPO_00423 5.3e-47
GBEEKLPO_00424 0.0 ctpE P E1-E2 ATPase
GBEEKLPO_00425 3.1e-60
GBEEKLPO_00427 0.0 S bacteriocin-associated integral membrane protein
GBEEKLPO_00428 3.5e-120 yujD V ABC transporter
GBEEKLPO_00429 1.5e-40 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
GBEEKLPO_00430 4.3e-258 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GBEEKLPO_00431 2.1e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
GBEEKLPO_00432 1.3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GBEEKLPO_00433 1.4e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
GBEEKLPO_00434 4.8e-97 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
GBEEKLPO_00435 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GBEEKLPO_00436 7e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GBEEKLPO_00437 4.1e-180 EGP Major facilitator Superfamily
GBEEKLPO_00438 1.2e-71 copY K negative regulation of transcription, DNA-templated
GBEEKLPO_00439 0.0 copA 3.6.3.54 P P-type ATPase
GBEEKLPO_00440 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
GBEEKLPO_00441 4.9e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GBEEKLPO_00442 3e-114 papP P ABC transporter (Permease
GBEEKLPO_00443 1.3e-106 P ABC transporter (Permease
GBEEKLPO_00444 5.2e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBEEKLPO_00445 3.3e-155 cjaA ET ABC transporter substrate-binding protein
GBEEKLPO_00446 8.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GBEEKLPO_00447 3.2e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
GBEEKLPO_00448 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GBEEKLPO_00449 8e-192 yjbB G Permeases of the major facilitator superfamily
GBEEKLPO_00450 8.6e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
GBEEKLPO_00451 7.8e-100 thiT S Thiamine transporter
GBEEKLPO_00452 2.5e-62 yjqA S Bacterial PH domain
GBEEKLPO_00453 7.4e-153 corA P CorA-like protein
GBEEKLPO_00454 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GBEEKLPO_00455 7e-43 yazA L endonuclease containing a URI domain
GBEEKLPO_00456 5.5e-141 yabB 2.1.1.223 L Methyltransferase
GBEEKLPO_00457 1.2e-156 nodB3 G deacetylase
GBEEKLPO_00458 9.8e-143 plsC 2.3.1.51 I Acyltransferase
GBEEKLPO_00459 2.1e-99 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
GBEEKLPO_00460 0.0 comEC S Competence protein ComEC
GBEEKLPO_00461 2.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GBEEKLPO_00462 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
GBEEKLPO_00463 3e-232 ytoI K transcriptional regulator containing CBS domains
GBEEKLPO_00464 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
GBEEKLPO_00465 2.8e-163 rbn E Belongs to the UPF0761 family
GBEEKLPO_00466 1.7e-85 ccl S cog cog4708
GBEEKLPO_00467 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GBEEKLPO_00468 7.4e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GBEEKLPO_00469 1.7e-182 yfjR K regulation of single-species biofilm formation
GBEEKLPO_00471 8e-74 S QueT transporter
GBEEKLPO_00472 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
GBEEKLPO_00474 5.5e-200 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBEEKLPO_00475 2.9e-17 yjdB S Domain of unknown function (DUF4767)
GBEEKLPO_00476 5.1e-167 tehB 2.1.1.265 PQ tellurite resistance protein tehb
GBEEKLPO_00477 2.8e-190 O protein import
GBEEKLPO_00478 2.1e-129 agrA KT phosphorelay signal transduction system
GBEEKLPO_00479 7.8e-198 2.7.13.3 T GHKL domain
GBEEKLPO_00481 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GBEEKLPO_00482 2.4e-37 ylqC L Belongs to the UPF0109 family
GBEEKLPO_00483 4.1e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GBEEKLPO_00484 0.0 ydaO E amino acid
GBEEKLPO_00485 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
GBEEKLPO_00486 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GBEEKLPO_00487 9e-294 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
GBEEKLPO_00488 1.1e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GBEEKLPO_00489 1.7e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GBEEKLPO_00490 7.3e-169 murB 1.3.1.98 M cell wall formation
GBEEKLPO_00491 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GBEEKLPO_00492 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
GBEEKLPO_00493 4.7e-132 potC P ABC-type spermidine putrescine transport system, permease component II
GBEEKLPO_00494 1.2e-205 potD P spermidine putrescine ABC transporter
GBEEKLPO_00495 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
GBEEKLPO_00496 1.3e-25 L Transposase (IS116 IS110 IS902 family)
GBEEKLPO_00497 1.3e-142 L PFAM transposase IS116 IS110 IS902 family
GBEEKLPO_00498 9.5e-39 gloA 4.4.1.5 E lactoylglutathione lyase activity
GBEEKLPO_00499 1.5e-11 gloA 4.4.1.5 E Lactoylglutathione lyase
GBEEKLPO_00500 5.9e-163 GK ROK family
GBEEKLPO_00501 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GBEEKLPO_00502 1e-104 wecD M Acetyltransferase (GNAT) domain
GBEEKLPO_00503 7.4e-222 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GBEEKLPO_00504 1.5e-236 L Transposase
GBEEKLPO_00505 3.4e-16 T peptidase
GBEEKLPO_00506 3e-14 coiA 3.6.4.12 S Competence protein
GBEEKLPO_00507 7.7e-111 L PFAM Integrase, catalytic core
GBEEKLPO_00508 9.8e-60 L PFAM Integrase, catalytic core
GBEEKLPO_00509 7.1e-109 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GBEEKLPO_00510 5.9e-108 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GBEEKLPO_00511 5.7e-172 S Helix-hairpin-helix DNA-binding motif class 1
GBEEKLPO_00512 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GBEEKLPO_00513 7.2e-164
GBEEKLPO_00514 1.4e-218 dcm 2.1.1.37 H cytosine-specific methyltransferase
GBEEKLPO_00515 1.2e-304
GBEEKLPO_00516 3.5e-56 lrgA S Effector of murein hydrolase LrgA
GBEEKLPO_00517 3.2e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GBEEKLPO_00518 7.6e-100 3.1.3.18 S IA, variant 1
GBEEKLPO_00519 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GBEEKLPO_00520 6e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GBEEKLPO_00521 2.2e-114 serB 3.1.3.3 E phosphoserine phosphatase
GBEEKLPO_00522 3.2e-07 N PFAM Uncharacterised protein family UPF0150
GBEEKLPO_00523 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
GBEEKLPO_00525 6.4e-63 ycaO O OsmC-like protein
GBEEKLPO_00526 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
GBEEKLPO_00527 5.7e-10 O ADP-ribosylglycohydrolase
GBEEKLPO_00528 1.2e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GBEEKLPO_00530 3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GBEEKLPO_00531 1.7e-17 XK27_00735
GBEEKLPO_00532 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBEEKLPO_00533 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
GBEEKLPO_00534 3.4e-169 S CAAX amino terminal protease family protein
GBEEKLPO_00536 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GBEEKLPO_00537 4.4e-91 MA20_25245 K Gnat family
GBEEKLPO_00538 6.4e-08 S the current gene model (or a revised gene model) may contain a frame shift
GBEEKLPO_00539 5.7e-85 mutT 3.6.1.55 F Nudix family
GBEEKLPO_00540 2.2e-140 ET ABC transporter
GBEEKLPO_00541 2.6e-138 ET Belongs to the bacterial solute-binding protein 3 family
GBEEKLPO_00542 7e-214 arcT 2.6.1.1 E Aminotransferase
GBEEKLPO_00543 5e-137 gltS ET Belongs to the bacterial solute-binding protein 3 family
GBEEKLPO_00544 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GBEEKLPO_00545 9.8e-51 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GBEEKLPO_00546 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GBEEKLPO_00547 2.3e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GBEEKLPO_00548 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
GBEEKLPO_00549 1.5e-172 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
GBEEKLPO_00550 4.3e-267 S Glucosyl transferase GtrII
GBEEKLPO_00551 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GBEEKLPO_00552 1.3e-227 amrA S membrane protein involved in the export of O-antigen and teichoic acid
GBEEKLPO_00553 6.5e-187 M Glycosyltransferase group 2 family protein
GBEEKLPO_00554 6.4e-128 arnC M group 2 family protein
GBEEKLPO_00555 1.8e-46 S Uncharacterized conserved protein (DUF2304)
GBEEKLPO_00556 2.2e-153 2.4.1.60 S Glycosyltransferase group 2 family protein
GBEEKLPO_00557 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
GBEEKLPO_00558 1.3e-224 M Psort location CytoplasmicMembrane, score
GBEEKLPO_00559 9.2e-239 GT4 M transferase activity, transferring glycosyl groups
GBEEKLPO_00560 3e-260 S Glucosyl transferase GtrII
GBEEKLPO_00561 2e-224 rgpA GT4 M Domain of unknown function (DUF1972)
GBEEKLPO_00562 1.7e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
GBEEKLPO_00563 6.8e-142 rgpC GM Transport permease protein
GBEEKLPO_00564 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GBEEKLPO_00565 0.0 rgpF M Rhamnan synthesis protein F
GBEEKLPO_00566 1.7e-101 radC E Belongs to the UPF0758 family
GBEEKLPO_00567 3.2e-132 puuD T peptidase C26
GBEEKLPO_00568 1.5e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GBEEKLPO_00569 8.2e-60 XK27_04120 S Putative amino acid metabolism
GBEEKLPO_00570 5.2e-209 iscS 2.8.1.7 E Cysteine desulfurase
GBEEKLPO_00571 7.8e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GBEEKLPO_00572 7.1e-101 yjbK S Adenylate cyclase
GBEEKLPO_00573 4.6e-120 yjbM 2.7.6.5 S Gtp pyrophosphokinase
GBEEKLPO_00574 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GBEEKLPO_00575 1.7e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GBEEKLPO_00576 2e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GBEEKLPO_00577 0.0 amiA E ABC transporter, substrate-binding protein, family 5
GBEEKLPO_00578 4.9e-279 amiC P ABC transporter (Permease
GBEEKLPO_00579 1.4e-167 amiD P ABC transporter (Permease
GBEEKLPO_00580 6e-202 oppD P Belongs to the ABC transporter superfamily
GBEEKLPO_00581 3.3e-172 oppF P Belongs to the ABC transporter superfamily
GBEEKLPO_00582 1.4e-131 V Psort location CytoplasmicMembrane, score
GBEEKLPO_00583 1.8e-119 skfE V abc transporter atp-binding protein
GBEEKLPO_00584 5e-63 yvoA_1 K Transcriptional
GBEEKLPO_00585 1.4e-147 supH S overlaps another CDS with the same product name
GBEEKLPO_00586 4.9e-148 XK27_02985 S overlaps another CDS with the same product name
GBEEKLPO_00587 6.4e-196 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GBEEKLPO_00588 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GBEEKLPO_00589 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
GBEEKLPO_00590 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GBEEKLPO_00591 8.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GBEEKLPO_00592 1.6e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GBEEKLPO_00593 4.8e-137 stp 3.1.3.16 T phosphatase
GBEEKLPO_00594 1.6e-306 prkC 2.7.11.1 KLT serine threonine protein kinase
GBEEKLPO_00595 3.1e-104 kcsA P Ion transport protein
GBEEKLPO_00596 3.3e-116 yvqF S Membrane
GBEEKLPO_00597 1.9e-170 vraS 2.7.13.3 T Histidine kinase
GBEEKLPO_00598 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBEEKLPO_00601 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GBEEKLPO_00602 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GBEEKLPO_00603 1.2e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GBEEKLPO_00604 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GBEEKLPO_00605 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
GBEEKLPO_00606 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GBEEKLPO_00607 2e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GBEEKLPO_00608 5.7e-187 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
GBEEKLPO_00609 1.8e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
GBEEKLPO_00610 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GBEEKLPO_00611 6.2e-102 2.3.1.128 K Acetyltransferase GNAT Family
GBEEKLPO_00612 9.4e-294 S Protein of unknown function (DUF3114)
GBEEKLPO_00614 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
GBEEKLPO_00615 8e-297 V abc transporter atp-binding protein
GBEEKLPO_00616 0.0 V abc transporter atp-binding protein
GBEEKLPO_00617 1.7e-193 XK27_10075 S abc transporter atp-binding protein
GBEEKLPO_00618 1.3e-52 L (ABC) transporter
GBEEKLPO_00619 0.0 glgE 2.3.1.12, 2.4.99.16, 3.2.1.1, 3.2.1.14 GH13,GH18 M Pilin isopeptide linkage domain protein
GBEEKLPO_00620 0.0 M Pilin isopeptide linkage domain protein
GBEEKLPO_00621 0.0 zmpB M signal peptide protein, YSIRK family
GBEEKLPO_00622 0.0 GM domain, Protein
GBEEKLPO_00623 9e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GBEEKLPO_00624 0.0 sbcC L ATPase involved in DNA repair
GBEEKLPO_00625 3.4e-155 cat 2.3.1.28 S acetyltransferase'
GBEEKLPO_00626 0.0 M family 8
GBEEKLPO_00627 9e-148 epsH S acetyltransferase'
GBEEKLPO_00628 6.2e-240 M Glycosyltransferase, family 8
GBEEKLPO_00629 1.1e-294 tagE 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GBEEKLPO_00630 5.6e-196 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GBEEKLPO_00631 3.3e-186 nss M transferase activity, transferring glycosyl groups
GBEEKLPO_00632 8.4e-237 M Glycosyltransferase, family 8
GBEEKLPO_00633 4.6e-168 cpsJ M Glycosyltransferase group 2 family protein
GBEEKLPO_00634 0.0 M lipopolysaccharide 3-alpha-galactosyltransferase activity
GBEEKLPO_00635 5.7e-70 M cog cog1442
GBEEKLPO_00636 1e-245 M family 8
GBEEKLPO_00637 1.7e-165 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
GBEEKLPO_00638 4.3e-311 asp1 S Accessory Sec system protein Asp1
GBEEKLPO_00639 1.5e-302 asp2 3.4.11.5 S Accessory Sec system protein Asp2
GBEEKLPO_00640 1.6e-68 asp3 S Accessory Sec system protein Asp3
GBEEKLPO_00641 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GBEEKLPO_00642 1.1e-12 S Accessory secretory protein Sec Asp4
GBEEKLPO_00643 7e-12 S Accessory secretory protein Sec, Asp5
GBEEKLPO_00647 1.7e-61 sraP UW Tetratricopeptide repeat
GBEEKLPO_00648 0.0 3.4.24.40 U Large extracellular alpha-helical protein
GBEEKLPO_00651 1e-18 3.2.1.51 GH95 U LPXTG cell wall anchor motif
GBEEKLPO_00652 5.1e-119 K Helix-turn-helix domain, rpiR family
GBEEKLPO_00653 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBEEKLPO_00654 0.0 3.5.1.28 M domain protein
GBEEKLPO_00655 8.8e-144 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
GBEEKLPO_00656 6.5e-91 maa 2.3.1.79 GK Maltose O-acetyltransferase
GBEEKLPO_00657 3.3e-68 rmaI K Transcriptional regulator, MarR family
GBEEKLPO_00658 2.6e-242 EGP Major facilitator Superfamily
GBEEKLPO_00659 1.3e-134 XK27_00785 S CAAX protease self-immunity
GBEEKLPO_00661 0.0 S dextransucrase activity
GBEEKLPO_00662 0.0 S dextransucrase activity
GBEEKLPO_00663 2.7e-309 S dextransucrase activity
GBEEKLPO_00664 0.0 M Putative cell wall binding repeat
GBEEKLPO_00665 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GBEEKLPO_00666 4.4e-106 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GBEEKLPO_00667 0.0 S dextransucrase activity
GBEEKLPO_00668 1.6e-240 tcdB S dextransucrase activity
GBEEKLPO_00669 0.0 M Putative cell wall binding repeat
GBEEKLPO_00670 0.0 S dextransucrase activity
GBEEKLPO_00671 0.0 S dextransucrase activity
GBEEKLPO_00672 0.0 S dextransucrase activity
GBEEKLPO_00673 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBEEKLPO_00674 8e-261 S dextransucrase activity
GBEEKLPO_00676 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBEEKLPO_00677 4.5e-124 yhfC S Putative membrane peptidase family (DUF2324)
GBEEKLPO_00678 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
GBEEKLPO_00679 4.7e-10 S Protein of unknown function (DUF1648)
GBEEKLPO_00680 4.8e-100 tnp* L An automated process has identified a potential problem with this gene model
GBEEKLPO_00681 1.4e-86 L Transposase
GBEEKLPO_00682 2.4e-08 S Enterocin A Immunity
GBEEKLPO_00683 0.0 pepO 3.4.24.71 O Peptidase family M13
GBEEKLPO_00684 2.1e-33 S Immunity protein 41
GBEEKLPO_00686 0.0 M Putative cell wall binding repeat
GBEEKLPO_00687 1e-229 thrE K Psort location CytoplasmicMembrane, score
GBEEKLPO_00688 1.3e-182 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
GBEEKLPO_00689 1.3e-99 dhaL 2.7.1.121 S Dihydroxyacetone kinase
GBEEKLPO_00690 2.6e-59 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
GBEEKLPO_00691 5.1e-184 XK27_10475 S oxidoreductase
GBEEKLPO_00692 4.3e-200 gldA 1.1.1.6 C glycerol dehydrogenase
GBEEKLPO_00694 2e-285 XK27_07020 S Belongs to the UPF0371 family
GBEEKLPO_00695 6.8e-181 vex1 V Efflux ABC transporter, permease protein
GBEEKLPO_00696 1e-108 vex2 V abc transporter atp-binding protein
GBEEKLPO_00697 2.2e-233 vex3 V Efflux ABC transporter, permease protein
GBEEKLPO_00698 1.5e-115 K Response regulator receiver domain protein
GBEEKLPO_00699 1.4e-229 vncS 2.7.13.3 T Histidine kinase
GBEEKLPO_00700 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
GBEEKLPO_00701 1.7e-182 galR K Transcriptional regulator
GBEEKLPO_00702 1.9e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GBEEKLPO_00703 3e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
GBEEKLPO_00704 8.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GBEEKLPO_00705 3.4e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
GBEEKLPO_00706 0.0 lacS G transporter
GBEEKLPO_00707 0.0 lacL 3.2.1.23 G -beta-galactosidase
GBEEKLPO_00708 4.2e-217 S Tetratricopeptide repeat
GBEEKLPO_00709 3.1e-161 yvgN C reductase
GBEEKLPO_00710 1.1e-30 XK27_10490
GBEEKLPO_00711 1.1e-40 DJ nuclease activity
GBEEKLPO_00712 1.6e-104 yoaK S Protein of unknown function (DUF1275)
GBEEKLPO_00713 1.7e-111 drgA C nitroreductase
GBEEKLPO_00714 9.9e-126 T Xre family transcriptional regulator
GBEEKLPO_00715 4.2e-153 T PhoQ Sensor
GBEEKLPO_00716 9.7e-94 S Psort location Cytoplasmic, score
GBEEKLPO_00717 4e-128 S ABC-2 family transporter protein
GBEEKLPO_00718 9.7e-169 bcrA V abc transporter atp-binding protein
GBEEKLPO_00719 4.5e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GBEEKLPO_00720 5.7e-155 E Alpha/beta hydrolase of unknown function (DUF915)
GBEEKLPO_00721 1.1e-77 ywnA K Transcriptional regulator
GBEEKLPO_00722 6.9e-161 1.13.11.2 S glyoxalase
GBEEKLPO_00723 1.3e-110 XK27_02070 S nitroreductase
GBEEKLPO_00724 2.2e-32
GBEEKLPO_00725 1.1e-27 XK27_07105 K transcriptional
GBEEKLPO_00727 5.9e-163 natA S abc transporter atp-binding protein
GBEEKLPO_00728 2.9e-213 natB CP ABC-type Na efflux pump, permease component
GBEEKLPO_00729 3.5e-174 ydhF S Aldo keto reductase
GBEEKLPO_00730 1.5e-98 K WHG domain
GBEEKLPO_00731 7e-124 V abc transporter atp-binding protein
GBEEKLPO_00732 3.5e-208 P FtsX-like permease family
GBEEKLPO_00733 1.5e-42 S Sugar efflux transporter for intercellular exchange
GBEEKLPO_00734 1.9e-37 yjgN S membrane
GBEEKLPO_00735 3.3e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
GBEEKLPO_00736 1.1e-178 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
GBEEKLPO_00737 5.6e-166 ET ABC transporter substrate-binding protein
GBEEKLPO_00738 5.7e-113 ytmL P ABC transporter (Permease
GBEEKLPO_00739 6e-115 yxeN P ABC transporter, permease protein
GBEEKLPO_00740 8.7e-139 tcyC2 3.6.3.21 E abc transporter atp-binding protein
GBEEKLPO_00741 0.0 S dextransucrase activity
GBEEKLPO_00742 5e-217 yfnA E amino acid
GBEEKLPO_00743 2.4e-143 S Carbohydrate-binding domain-containing protein Cthe_2159
GBEEKLPO_00744 1.4e-16 csbD S CsbD-like
GBEEKLPO_00745 1.5e-107 S Protein of unknown function (DUF421)
GBEEKLPO_00746 1.8e-59 S Protein of unknown function (DUF3290)
GBEEKLPO_00747 1.9e-183 manA 5.3.1.8 G mannose-6-phosphate isomerase
GBEEKLPO_00748 3.9e-235 brnQ E Component of the transport system for branched-chain amino acids
GBEEKLPO_00749 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GBEEKLPO_00751 1.3e-246 norM V Multidrug efflux pump
GBEEKLPO_00752 4.7e-154 K sequence-specific DNA binding
GBEEKLPO_00753 8.3e-269 V (ABC) transporter
GBEEKLPO_00754 3.8e-224 pbuX F xanthine permease
GBEEKLPO_00755 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GBEEKLPO_00756 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBEEKLPO_00757 2e-151 T Histidine kinase
GBEEKLPO_00758 2.9e-134 macB2 V ABC transporter, ATP-binding protein
GBEEKLPO_00759 0.0 V ABC transporter (permease)
GBEEKLPO_00760 6.1e-93 XK27_05000 S metal cluster binding
GBEEKLPO_00761 1.7e-29 liaI KT membrane
GBEEKLPO_00762 1.7e-16 liaI KT membrane
GBEEKLPO_00763 6.5e-162 XK27_09825 V abc transporter atp-binding protein
GBEEKLPO_00764 4e-133 yvfS V Transporter
GBEEKLPO_00765 1.6e-66 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
GBEEKLPO_00766 1.3e-165 yocS S Transporter
GBEEKLPO_00769 1.6e-160 XK27_09825 V abc transporter atp-binding protein
GBEEKLPO_00770 2.6e-132 yvfS V ABC-2 type transporter
GBEEKLPO_00771 3e-193 desK 2.7.13.3 T Histidine kinase
GBEEKLPO_00772 1.8e-102 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GBEEKLPO_00773 8.7e-119
GBEEKLPO_00774 2.8e-88
GBEEKLPO_00776 2.2e-22
GBEEKLPO_00777 1.9e-81
GBEEKLPO_00778 2.2e-165 K sequence-specific DNA binding
GBEEKLPO_00779 5.3e-106 S ABC-2 family transporter protein
GBEEKLPO_00780 4e-153 V ABC transporter, ATP-binding protein
GBEEKLPO_00781 4.2e-164 K sequence-specific DNA binding
GBEEKLPO_00782 2.1e-80 3.4.21.89 S RDD family
GBEEKLPO_00783 1.5e-164 yjlA EG membrane
GBEEKLPO_00784 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
GBEEKLPO_00785 7.3e-150 sdaAA 4.3.1.17 E L-serine dehydratase
GBEEKLPO_00786 1.7e-122 sdaAB 4.3.1.17 E L-serine dehydratase
GBEEKLPO_00787 1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
GBEEKLPO_00788 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GBEEKLPO_00789 2.3e-273 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GBEEKLPO_00790 1.1e-92 pat 2.3.1.183 M acetyltransferase
GBEEKLPO_00791 1.4e-300 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GBEEKLPO_00792 1.8e-124 alkD L Dna alkylation repair
GBEEKLPO_00793 1.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GBEEKLPO_00794 1.7e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GBEEKLPO_00795 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GBEEKLPO_00796 0.0 smc D Required for chromosome condensation and partitioning
GBEEKLPO_00797 1e-93 S Protein of unknown function (DUF3278)
GBEEKLPO_00798 2.9e-22 WQ51_00220 K Helix-turn-helix domain
GBEEKLPO_00799 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GBEEKLPO_00800 3.4e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GBEEKLPO_00801 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GBEEKLPO_00803 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
GBEEKLPO_00804 4.6e-193 L PFAM Integrase, catalytic core
GBEEKLPO_00805 3.4e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GBEEKLPO_00807 2.6e-86 S ECF-type riboflavin transporter, S component
GBEEKLPO_00808 2.2e-162 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
GBEEKLPO_00809 6.6e-85 XK27_01265 S ECF-type riboflavin transporter, S component
GBEEKLPO_00810 1.1e-294 yfmM S abc transporter atp-binding protein
GBEEKLPO_00811 1.4e-256 noxE P NADH oxidase
GBEEKLPO_00812 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GBEEKLPO_00813 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GBEEKLPO_00814 3.2e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
GBEEKLPO_00815 3.9e-74 yaeR E COG0346 Lactoylglutathione lyase and related lyases
GBEEKLPO_00816 5.8e-164 ypuA S secreted protein
GBEEKLPO_00817 2.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
GBEEKLPO_00818 4.4e-45 rpmE2 J 50S ribosomal protein L31
GBEEKLPO_00819 3.4e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GBEEKLPO_00820 9e-178 nrnA 3.1.13.3, 3.1.3.7 S domain protein
GBEEKLPO_00821 1.5e-154 gst O Glutathione S-transferase
GBEEKLPO_00822 2.1e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GBEEKLPO_00823 2.8e-108 tdk 2.7.1.21 F thymidine kinase
GBEEKLPO_00824 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GBEEKLPO_00825 3.1e-150 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GBEEKLPO_00826 1.3e-108 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GBEEKLPO_00827 6.2e-235 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GBEEKLPO_00828 2.5e-178 ndpA S 37-kD nucleoid-associated bacterial protein
GBEEKLPO_00829 1.4e-99 pvaA M lytic transglycosylase activity
GBEEKLPO_00830 2.2e-294 yfiB1 V abc transporter atp-binding protein
GBEEKLPO_00831 0.0 XK27_10035 V abc transporter atp-binding protein
GBEEKLPO_00832 1.3e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBEEKLPO_00833 1.7e-237 dltB M Membrane protein involved in D-alanine export
GBEEKLPO_00834 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GBEEKLPO_00835 7.9e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GBEEKLPO_00836 0.0 3.6.3.8 P cation transport ATPase
GBEEKLPO_00837 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
GBEEKLPO_00839 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GBEEKLPO_00840 3.3e-166 metF 1.5.1.20 E reductase
GBEEKLPO_00841 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
GBEEKLPO_00842 2.9e-91 panT S Psort location CytoplasmicMembrane, score
GBEEKLPO_00843 6.4e-94 panT S ECF transporter, substrate-specific component
GBEEKLPO_00844 1e-93 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GBEEKLPO_00845 7.3e-121 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
GBEEKLPO_00846 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GBEEKLPO_00847 2.5e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBEEKLPO_00848 1.5e-240 T PhoQ Sensor
GBEEKLPO_00849 1e-29 rpsT J Binds directly to 16S ribosomal RNA
GBEEKLPO_00850 1.4e-172 coaA 2.7.1.33 F Pantothenic acid kinase
GBEEKLPO_00851 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
GBEEKLPO_00852 2.9e-235 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
GBEEKLPO_00853 3.2e-113 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GBEEKLPO_00854 1.1e-68 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GBEEKLPO_00855 1.1e-192 tcsA S membrane
GBEEKLPO_00856 2.9e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
GBEEKLPO_00857 1.3e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
GBEEKLPO_00858 3.1e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
GBEEKLPO_00859 2.8e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
GBEEKLPO_00860 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GBEEKLPO_00861 1.1e-81 ypmB S Protein conserved in bacteria
GBEEKLPO_00862 2.8e-213 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
GBEEKLPO_00863 1.1e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GBEEKLPO_00864 1.4e-18
GBEEKLPO_00865 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
GBEEKLPO_00866 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GBEEKLPO_00867 1.8e-83 queD 4.1.2.50, 4.2.3.12 H synthase
GBEEKLPO_00868 1.2e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GBEEKLPO_00869 5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
GBEEKLPO_00870 1e-210 D nuclear chromosome segregation
GBEEKLPO_00871 3.7e-137 yejC S cyclic nucleotide-binding protein
GBEEKLPO_00872 7e-164 rapZ S Displays ATPase and GTPase activities
GBEEKLPO_00873 4.3e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GBEEKLPO_00874 6.7e-162 whiA K May be required for sporulation
GBEEKLPO_00875 1.3e-278 pepD E Dipeptidase
GBEEKLPO_00876 5.8e-149 XK27_10720 D peptidase activity
GBEEKLPO_00877 3.3e-294 adcA P Belongs to the bacterial solute-binding protein 9 family
GBEEKLPO_00878 2.6e-09
GBEEKLPO_00880 5.5e-173 yeiH S Membrane
GBEEKLPO_00881 2e-129 mur1 3.4.17.14, 3.5.1.28 NU muramidase
GBEEKLPO_00882 7.6e-166 cpsY K Transcriptional regulator
GBEEKLPO_00883 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GBEEKLPO_00884 2.4e-49 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_00885 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
GBEEKLPO_00886 1.4e-105 artQ P ABC transporter (Permease
GBEEKLPO_00887 4e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBEEKLPO_00888 4.9e-159 aatB ET ABC transporter substrate-binding protein
GBEEKLPO_00889 2.1e-271 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GBEEKLPO_00890 2.6e-51
GBEEKLPO_00891 1.9e-46
GBEEKLPO_00892 3e-57 adhP 1.1.1.1 P alcohol dehydrogenase
GBEEKLPO_00893 9.3e-40 adhP 1.1.1.1 P alcohol dehydrogenase
GBEEKLPO_00894 2.3e-31 adhP 1.1.1.1 P alcohol dehydrogenase
GBEEKLPO_00895 5.1e-107 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GBEEKLPO_00896 1.2e-20 L transposase and inactivated derivatives, IS30 family
GBEEKLPO_00897 2.2e-72 L PFAM Integrase, catalytic core
GBEEKLPO_00898 2.9e-162 V AAA domain, putative AbiEii toxin, Type IV TA system
GBEEKLPO_00899 2.4e-56 S ABC-2 type transporter
GBEEKLPO_00900 2.3e-99
GBEEKLPO_00901 6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GBEEKLPO_00902 2.7e-126 gntR1 K transcriptional
GBEEKLPO_00903 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GBEEKLPO_00904 1e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GBEEKLPO_00905 2.7e-86
GBEEKLPO_00906 2.7e-91 niaR S small molecule binding protein (contains 3H domain)
GBEEKLPO_00907 1.3e-128 K DNA-binding helix-turn-helix protein
GBEEKLPO_00908 2.5e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GBEEKLPO_00909 4.8e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GBEEKLPO_00910 2.3e-170 GK ROK family
GBEEKLPO_00911 2.4e-158 dprA LU DNA protecting protein DprA
GBEEKLPO_00912 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GBEEKLPO_00913 1.3e-151 S TraX protein
GBEEKLPO_00914 2.2e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBEEKLPO_00915 4.7e-236 T PhoQ Sensor
GBEEKLPO_00916 1.1e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GBEEKLPO_00917 1.4e-225 XK27_05470 E Methionine synthase
GBEEKLPO_00918 6.6e-53 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GBEEKLPO_00919 6.7e-254 V Glucan-binding protein C
GBEEKLPO_00920 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GBEEKLPO_00921 1.5e-233 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GBEEKLPO_00922 5.7e-100 S Protein of unknown function (DUF1697)
GBEEKLPO_00923 1.8e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GBEEKLPO_00924 4.7e-182 clcA_2 P Chloride transporter, ClC family
GBEEKLPO_00925 1.5e-137 yfeJ 6.3.5.2 F glutamine amidotransferase
GBEEKLPO_00926 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
GBEEKLPO_00927 1e-20 L the current gene model (or a revised gene model) may contain a frame shift
GBEEKLPO_00929 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GBEEKLPO_00932 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GBEEKLPO_00933 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
GBEEKLPO_00934 2.7e-193 L PFAM Integrase, catalytic core
GBEEKLPO_00935 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
GBEEKLPO_00936 1.5e-133 cbiQ P cobalt transport
GBEEKLPO_00937 1.1e-158 P abc transporter atp-binding protein
GBEEKLPO_00938 2.3e-150 cbiO2 P 'abc transporter, ATP-binding protein
GBEEKLPO_00939 9.1e-39 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
GBEEKLPO_00940 3.3e-194 yegU O ADP-ribosylglycohydrolase
GBEEKLPO_00941 9.4e-253 F Belongs to the purine-cytosine permease (2.A.39) family
GBEEKLPO_00942 1.9e-169 G Belongs to the carbohydrate kinase PfkB family
GBEEKLPO_00943 7.8e-10
GBEEKLPO_00944 7.7e-61 S Protein of unknown function with HXXEE motif
GBEEKLPO_00945 1.4e-104 K Transcriptional regulator, TetR family
GBEEKLPO_00946 2.4e-164 czcD P cation diffusion facilitator family transporter
GBEEKLPO_00947 6.7e-201 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GBEEKLPO_00948 1.4e-31 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
GBEEKLPO_00949 1.7e-114 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
GBEEKLPO_00950 7e-161 K Transcriptional regulator
GBEEKLPO_00951 4.9e-187 S Hydrolases of the alpha beta superfamily
GBEEKLPO_00952 4.6e-70 S Alpha/beta hydrolase of unknown function (DUF915)
GBEEKLPO_00953 1.2e-79 G protein with an alpha beta hydrolase fold
GBEEKLPO_00954 6.5e-128 ybhF_2 V abc transporter atp-binding protein
GBEEKLPO_00955 1.7e-180 ybhR V ABC transporter
GBEEKLPO_00956 3.7e-111 K Bacterial regulatory proteins, tetR family
GBEEKLPO_00957 2.4e-135 udp 2.4.2.3 F phosphorylase
GBEEKLPO_00958 2.2e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
GBEEKLPO_00959 1.9e-88 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_00960 2.4e-170 S von Willebrand factor (vWF) type A domain
GBEEKLPO_00961 8.1e-182 yclQ P ABC-type enterochelin transport system, periplasmic component
GBEEKLPO_00962 5.5e-237 dinF V Mate efflux family protein
GBEEKLPO_00963 1.2e-283 S Psort location CytoplasmicMembrane, score
GBEEKLPO_00964 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
GBEEKLPO_00965 1.8e-142 S TraX protein
GBEEKLPO_00966 2e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
GBEEKLPO_00967 3.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GBEEKLPO_00968 4.5e-177 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GBEEKLPO_00969 5.3e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GBEEKLPO_00970 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GBEEKLPO_00971 1.8e-37 nylA 3.5.1.4 J amidase activity
GBEEKLPO_00972 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
GBEEKLPO_00973 2.6e-174 bglC K Transcriptional regulator
GBEEKLPO_00974 2.3e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GBEEKLPO_00975 4.3e-242 agcS E (Alanine) symporter
GBEEKLPO_00976 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GBEEKLPO_00977 5.9e-241 metY 2.5.1.49 E o-acetylhomoserine
GBEEKLPO_00978 2e-143 S haloacid dehalogenase-like hydrolase
GBEEKLPO_00979 2.7e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GBEEKLPO_00980 1.3e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
GBEEKLPO_00981 4.7e-35 M1-755 S Domain of unknown function (DUF1858)
GBEEKLPO_00982 4.8e-249 XK27_04775 S hemerythrin HHE cation binding domain
GBEEKLPO_00983 3.2e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GBEEKLPO_00984 6.4e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GBEEKLPO_00985 1.6e-70 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GBEEKLPO_00986 1e-44 yktA S Belongs to the UPF0223 family
GBEEKLPO_00987 2e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
GBEEKLPO_00988 7.2e-258 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
GBEEKLPO_00989 1.1e-156 pstS P phosphate
GBEEKLPO_00990 1.1e-156 pstC P probably responsible for the translocation of the substrate across the membrane
GBEEKLPO_00991 1.5e-155 pstA P phosphate transport system permease
GBEEKLPO_00992 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GBEEKLPO_00993 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GBEEKLPO_00994 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
GBEEKLPO_00995 0.0 pepN 3.4.11.2 E aminopeptidase
GBEEKLPO_00996 1.2e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
GBEEKLPO_00997 3.6e-90
GBEEKLPO_01000 3.8e-187 lplA 6.3.1.20 H Lipoate-protein ligase
GBEEKLPO_01001 1.7e-37
GBEEKLPO_01002 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GBEEKLPO_01003 7.1e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
GBEEKLPO_01004 4.9e-182 malR K Transcriptional regulator
GBEEKLPO_01005 3.9e-229 malX G ABC transporter
GBEEKLPO_01006 4.8e-249 malF P ABC transporter (Permease
GBEEKLPO_01007 7.5e-152 malG P ABC transporter (Permease
GBEEKLPO_01008 4.7e-213 msmX P Belongs to the ABC transporter superfamily
GBEEKLPO_01009 1e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GBEEKLPO_01010 4e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GBEEKLPO_01011 9.7e-292 ywbL P COG0672 High-affinity Fe2 Pb2 permease
GBEEKLPO_01012 3.9e-234 ycdB P peroxidase
GBEEKLPO_01013 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
GBEEKLPO_01014 4e-179 fatB P ABC-type enterochelin transport system, periplasmic component
GBEEKLPO_01015 1.2e-135 yclP 3.6.3.34 P abc transporter atp-binding protein
GBEEKLPO_01016 1.2e-156 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBEEKLPO_01017 1.8e-128 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBEEKLPO_01018 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
GBEEKLPO_01019 2.9e-85 lytC 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GBEEKLPO_01020 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
GBEEKLPO_01021 0.0 lpdA 1.8.1.4 C Dehydrogenase
GBEEKLPO_01022 3.1e-219 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GBEEKLPO_01023 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GBEEKLPO_01024 7.8e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
GBEEKLPO_01025 1.1e-215 hpk9 2.7.13.3 T protein histidine kinase activity
GBEEKLPO_01026 9.9e-236 2.7.13.3 T protein histidine kinase activity
GBEEKLPO_01028 1.1e-169 cas2 2.7.7.7 L CRISPR-associated endoribonuclease Cas2
GBEEKLPO_01029 2.1e-171 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GBEEKLPO_01030 7.6e-112 casE S CRISPR system CASCADE complex protein CasE
GBEEKLPO_01031 7.7e-137 casD S CRISPR system CASCADE complex protein CasD
GBEEKLPO_01032 1.4e-182 casC L CT1975-like protein
GBEEKLPO_01033 7.5e-106 casB S CRISPR system CASCADE complex protein CasB
GBEEKLPO_01034 0.0 casA L An automated process has identified a potential problem with this gene model
GBEEKLPO_01035 0.0 cas3 L CRISPR-associated helicase cas3
GBEEKLPO_01036 5.6e-100 L PFAM Integrase, catalytic core
GBEEKLPO_01037 2e-85 L PFAM Integrase, catalytic core
GBEEKLPO_01038 0.0 S the current gene model (or a revised gene model) may contain a frame shift
GBEEKLPO_01039 7.5e-236 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GBEEKLPO_01040 1.7e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GBEEKLPO_01041 6e-219 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GBEEKLPO_01042 2.4e-253 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
GBEEKLPO_01043 1.5e-160 rssA S Phospholipase, patatin family
GBEEKLPO_01044 6.7e-105 estA E Lysophospholipase L1 and related esterases
GBEEKLPO_01045 4.7e-288 S unusual protein kinase
GBEEKLPO_01046 4.9e-39 S granule-associated protein
GBEEKLPO_01047 9.2e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GBEEKLPO_01048 3.5e-200 S hmm pf01594
GBEEKLPO_01049 1.5e-109 G Belongs to the phosphoglycerate mutase family
GBEEKLPO_01050 7e-107 G Belongs to the phosphoglycerate mutase family
GBEEKLPO_01051 2.5e-109 pgm G Belongs to the phosphoglycerate mutase family
GBEEKLPO_01052 1.3e-153 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GBEEKLPO_01053 8.4e-243 L Transposase
GBEEKLPO_01054 1.5e-245 S Polysaccharide biosynthesis protein
GBEEKLPO_01055 0.0 M Polysaccharide biosynthesis protein
GBEEKLPO_01056 5.3e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GBEEKLPO_01057 5.4e-172 S glycosyl transferase family 2
GBEEKLPO_01058 9.5e-60
GBEEKLPO_01059 2e-205 M glycosyl transferase group 1
GBEEKLPO_01060 1.1e-164 S Glycosyl transferase family 2
GBEEKLPO_01061 5.1e-161 licD M LICD family
GBEEKLPO_01062 4.3e-127 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GBEEKLPO_01063 1.3e-257 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
GBEEKLPO_01064 6.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
GBEEKLPO_01065 7.2e-116 cps4C M biosynthesis protein
GBEEKLPO_01066 3.5e-137 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
GBEEKLPO_01067 8e-242 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
GBEEKLPO_01068 1.3e-142 L PFAM transposase IS116 IS110 IS902 family
GBEEKLPO_01069 1.1e-65 L Transposase (IS116 IS110 IS902 family)
GBEEKLPO_01070 3.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
GBEEKLPO_01071 3.3e-277 pepV 3.5.1.18 E Dipeptidase
GBEEKLPO_01072 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GBEEKLPO_01073 4.9e-93 yybC
GBEEKLPO_01074 1.4e-86 XK27_03610 K Gnat family
GBEEKLPO_01075 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GBEEKLPO_01076 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GBEEKLPO_01077 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GBEEKLPO_01078 4.3e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GBEEKLPO_01079 5.5e-17 M LysM domain
GBEEKLPO_01080 1.1e-86 ebsA S Family of unknown function (DUF5322)
GBEEKLPO_01081 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GBEEKLPO_01082 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GBEEKLPO_01083 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GBEEKLPO_01084 4.4e-225 G COG0457 FOG TPR repeat
GBEEKLPO_01085 1.3e-178 yubA S permease
GBEEKLPO_01086 1.7e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
GBEEKLPO_01087 2.1e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GBEEKLPO_01088 3.2e-124 ftsE D cell division ATP-binding protein FtsE
GBEEKLPO_01089 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GBEEKLPO_01090 1.4e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GBEEKLPO_01091 5.6e-163 yjjH S Calcineurin-like phosphoesterase
GBEEKLPO_01092 9.7e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GBEEKLPO_01093 0.0 pacL 3.6.3.8 P cation transport ATPase
GBEEKLPO_01094 5.3e-68 ywiB S Domain of unknown function (DUF1934)
GBEEKLPO_01095 8.4e-142 XK27_00120 2.4.2.3 F Phosphorylase superfamily
GBEEKLPO_01096 1.7e-159 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
GBEEKLPO_01097 2e-146 yidA S hydrolases of the HAD superfamily
GBEEKLPO_01098 4.1e-207 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
GBEEKLPO_01099 1.9e-88 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_01100 1e-57 S Protein of unknown function (DUF454)
GBEEKLPO_01101 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
GBEEKLPO_01102 1.6e-236 vicK 2.7.13.3 T Histidine kinase
GBEEKLPO_01103 1.7e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBEEKLPO_01104 1.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBEEKLPO_01105 3.8e-148 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
GBEEKLPO_01106 1.9e-116 gltJ P ABC transporter (Permease
GBEEKLPO_01107 2.9e-111 tcyB_2 P ABC transporter (permease)
GBEEKLPO_01108 3.6e-152 endA F DNA RNA non-specific endonuclease
GBEEKLPO_01109 2.5e-26 epuA S DNA-directed RNA polymerase subunit beta
GBEEKLPO_01110 2e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GBEEKLPO_01112 2e-208 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
GBEEKLPO_01113 5.5e-250 ydaM M Glycosyltransferases, probably involved in cell wall biogenesis
GBEEKLPO_01115 2.6e-138
GBEEKLPO_01116 1.7e-215 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GBEEKLPO_01117 4.4e-73 L PFAM Integrase, catalytic core
GBEEKLPO_01118 3.3e-67 L transposase and inactivated derivatives, IS30 family
GBEEKLPO_01119 9.2e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GBEEKLPO_01120 3.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GBEEKLPO_01121 2.6e-305 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GBEEKLPO_01122 3.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
GBEEKLPO_01123 1.1e-167 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GBEEKLPO_01124 6.5e-21 WQ51_02665 S Protein of unknown function (DUF3042)
GBEEKLPO_01125 6.6e-08
GBEEKLPO_01126 5.6e-132 K cell adhesion
GBEEKLPO_01127 1e-75 int3 L DNA integration
GBEEKLPO_01129 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GBEEKLPO_01130 1e-218 XK27_05110 P Chloride transporter ClC family
GBEEKLPO_01131 1.9e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
GBEEKLPO_01132 1.5e-283 clcA P Chloride transporter, ClC family
GBEEKLPO_01133 1e-75 fld C Flavodoxin
GBEEKLPO_01134 2.2e-18 XK27_08880
GBEEKLPO_01135 5.5e-127 XK27_08875 O Zinc-dependent metalloprotease
GBEEKLPO_01136 2e-151 estA CE1 S Esterase
GBEEKLPO_01137 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GBEEKLPO_01138 3.1e-136 XK27_08845 S abc transporter atp-binding protein
GBEEKLPO_01139 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
GBEEKLPO_01140 4.3e-178 XK27_08835 S ABC transporter substrate binding protein
GBEEKLPO_01141 3.8e-18 S Domain of unknown function (DUF4649)
GBEEKLPO_01142 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GBEEKLPO_01143 1.6e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GBEEKLPO_01144 0.0 dnaE 2.7.7.7 L DNA polymerase
GBEEKLPO_01145 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GBEEKLPO_01146 5.6e-277 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GBEEKLPO_01147 3.5e-37 ysdA L Membrane
GBEEKLPO_01148 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GBEEKLPO_01149 5.8e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GBEEKLPO_01150 1.5e-55 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GBEEKLPO_01151 2e-70 S SnoaL-like polyketide cyclase
GBEEKLPO_01152 5.4e-53 hxlR K HxlR-like helix-turn-helix
GBEEKLPO_01153 2.7e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GBEEKLPO_01154 6.2e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
GBEEKLPO_01156 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GBEEKLPO_01157 6.2e-97 ypmS S Protein conserved in bacteria
GBEEKLPO_01158 2.2e-162 ypmR E COG2755 Lysophospholipase L1 and related esterases
GBEEKLPO_01159 2.4e-150 DegV S DegV family
GBEEKLPO_01160 4.9e-304 recN L May be involved in recombinational repair of damaged DNA
GBEEKLPO_01161 7.5e-74 argR K Regulates arginine biosynthesis genes
GBEEKLPO_01162 7.7e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GBEEKLPO_01163 2.5e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GBEEKLPO_01164 3.5e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GBEEKLPO_01165 4.6e-236 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GBEEKLPO_01166 6e-07 KT response to antibiotic
GBEEKLPO_01167 4.5e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GBEEKLPO_01168 3.5e-126 dnaD
GBEEKLPO_01169 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GBEEKLPO_01170 6.8e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GBEEKLPO_01171 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
GBEEKLPO_01172 2.1e-67 GnaT 2.5.1.16 K acetyltransferase
GBEEKLPO_01173 2.8e-131 Q Methyltransferase domain
GBEEKLPO_01174 4.6e-140 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GBEEKLPO_01175 5.9e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GBEEKLPO_01176 6.9e-113 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
GBEEKLPO_01177 7.6e-247 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GBEEKLPO_01178 5.4e-235 rodA D Belongs to the SEDS family
GBEEKLPO_01179 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBEEKLPO_01180 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBEEKLPO_01181 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GBEEKLPO_01182 1.9e-181 XK27_08075 M glycosyl transferase family 2
GBEEKLPO_01183 3.2e-109 S Carbohydrate-binding domain-containing protein Cthe_2159
GBEEKLPO_01184 1.4e-147 P molecular chaperone
GBEEKLPO_01185 3.7e-96 XK27_05505 S Psort location CytoplasmicMembrane, score
GBEEKLPO_01187 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
GBEEKLPO_01188 3.6e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GBEEKLPO_01189 7.3e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GBEEKLPO_01190 4.8e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GBEEKLPO_01191 9.4e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GBEEKLPO_01192 5.1e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
GBEEKLPO_01193 3.7e-235 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GBEEKLPO_01194 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GBEEKLPO_01195 1.4e-178 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GBEEKLPO_01196 4.3e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GBEEKLPO_01197 1.1e-60 XK27_08085
GBEEKLPO_01198 5.6e-148 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
GBEEKLPO_01199 1e-139 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
GBEEKLPO_01200 6.5e-119 ylfI S tigr01906
GBEEKLPO_01201 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GBEEKLPO_01202 1.3e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
GBEEKLPO_01203 8.2e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
GBEEKLPO_01204 3.7e-30 KT response to antibiotic
GBEEKLPO_01205 1.9e-88 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_01207 7.3e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GBEEKLPO_01208 6.4e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GBEEKLPO_01209 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GBEEKLPO_01210 1e-259 S phospholipase Carboxylesterase
GBEEKLPO_01211 2.8e-207 yurR 1.4.5.1 E oxidoreductase
GBEEKLPO_01212 1.6e-146 zupT P Mediates zinc uptake. May also transport other divalent cations
GBEEKLPO_01213 6.2e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GBEEKLPO_01214 1.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
GBEEKLPO_01215 1.8e-66 gtrA S GtrA-like protein
GBEEKLPO_01216 3.3e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GBEEKLPO_01217 6e-169 ybbR S Protein conserved in bacteria
GBEEKLPO_01218 1.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GBEEKLPO_01219 3.6e-257 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
GBEEKLPO_01220 2.3e-150 cobQ S glutamine amidotransferase
GBEEKLPO_01221 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GBEEKLPO_01222 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
GBEEKLPO_01223 1.2e-29 MA20_06245 S yiaA/B two helix domain
GBEEKLPO_01224 0.0 uup S abc transporter atp-binding protein
GBEEKLPO_01225 6.2e-114 udk 2.7.1.48 F Cytidine monophosphokinase
GBEEKLPO_01226 3.2e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
GBEEKLPO_01227 9.9e-227 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
GBEEKLPO_01228 2.7e-153 XK27_05675 S Esterase
GBEEKLPO_01229 6.1e-162 XK27_05670 S Putative esterase
GBEEKLPO_01230 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
GBEEKLPO_01231 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GBEEKLPO_01232 3e-38 ptsH G phosphocarrier protein Hpr
GBEEKLPO_01233 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
GBEEKLPO_01234 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
GBEEKLPO_01235 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GBEEKLPO_01236 6.5e-34 nrdH O Glutaredoxin
GBEEKLPO_01237 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBEEKLPO_01238 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GBEEKLPO_01239 5.1e-237 L Transposase
GBEEKLPO_01240 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GBEEKLPO_01241 8.4e-138 divIVA D Cell division initiation protein
GBEEKLPO_01242 5e-145 ylmH S conserved protein, contains S4-like domain
GBEEKLPO_01243 6.5e-30 yggT D integral membrane protein
GBEEKLPO_01244 3.2e-101 sepF D cell septum assembly
GBEEKLPO_01245 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GBEEKLPO_01246 1.7e-238 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GBEEKLPO_01247 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GBEEKLPO_01248 6.5e-110 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GBEEKLPO_01249 1.3e-12 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GBEEKLPO_01250 3.9e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GBEEKLPO_01251 5.5e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GBEEKLPO_01253 0.0 typA T GTP-binding protein TypA
GBEEKLPO_01254 1.4e-178 glk 2.7.1.2 G Glucokinase
GBEEKLPO_01255 2.4e-27 yqgQ S protein conserved in bacteria
GBEEKLPO_01256 5.2e-83 perR P Belongs to the Fur family
GBEEKLPO_01257 9.3e-92 dps P Belongs to the Dps family
GBEEKLPO_01258 7.5e-115 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
GBEEKLPO_01259 3.6e-172 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
GBEEKLPO_01260 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
GBEEKLPO_01261 1.3e-185 holA 2.7.7.7 L DNA polymerase III delta subunit
GBEEKLPO_01262 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GBEEKLPO_01263 5.6e-65 S Domain of unknown function (DUF4430)
GBEEKLPO_01264 3.2e-75 S Psort location CytoplasmicMembrane, score
GBEEKLPO_01265 3.4e-132 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
GBEEKLPO_01266 3.8e-135 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
GBEEKLPO_01267 1.5e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
GBEEKLPO_01268 1e-119 sirR K iron dependent repressor
GBEEKLPO_01269 4e-135 htpX O Belongs to the peptidase M48B family
GBEEKLPO_01270 1.2e-92 lemA S LemA family
GBEEKLPO_01271 8.1e-177 spd F DNA RNA non-specific endonuclease
GBEEKLPO_01272 0.0 2.4.1.21 GT5 M Right handed beta helix region
GBEEKLPO_01273 5e-162 S double-stranded DNA endodeoxyribonuclease activity
GBEEKLPO_01274 7.4e-200 higA K Pfam:DUF955
GBEEKLPO_01275 2.3e-51
GBEEKLPO_01276 6.6e-306 hsdM 2.1.1.72 V type I restriction-modification system
GBEEKLPO_01277 3e-136 S Protein conserved in bacteria
GBEEKLPO_01278 1.4e-242 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
GBEEKLPO_01279 2.4e-309 S cog cog0433
GBEEKLPO_01280 4.9e-254 S SIR2-like domain
GBEEKLPO_01281 9.8e-123
GBEEKLPO_01282 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
GBEEKLPO_01283 1.7e-45 K Helix-turn-helix domain
GBEEKLPO_01284 4.4e-45 S Phage derived protein Gp49-like (DUF891)
GBEEKLPO_01285 4.5e-135 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GBEEKLPO_01286 9.5e-222 MA20_36090 S Protein of unknown function (DUF2974)
GBEEKLPO_01287 1.6e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GBEEKLPO_01288 1.4e-161 5.2.1.8 G hydrolase
GBEEKLPO_01289 5.3e-27 P Hemerythrin HHE cation binding domain protein
GBEEKLPO_01290 1.6e-144 XK27_00880 3.4.17.14, 3.5.1.28 M Glycosyl hydrolase, family 25
GBEEKLPO_01291 2.7e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GBEEKLPO_01292 6e-117 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
GBEEKLPO_01293 5.2e-175 S hydrolase
GBEEKLPO_01294 8.4e-23
GBEEKLPO_01295 6.7e-152 M LysM domain
GBEEKLPO_01296 7.5e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GBEEKLPO_01298 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
GBEEKLPO_01299 1.8e-33 XK27_12190 S protein conserved in bacteria
GBEEKLPO_01301 1e-88 bioY S biotin synthase
GBEEKLPO_01302 4.4e-252 yegQ O Peptidase U32
GBEEKLPO_01303 4e-178 yegQ O Peptidase U32
GBEEKLPO_01305 8.5e-70 ytxH S General stress protein
GBEEKLPO_01306 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GBEEKLPO_01307 3.3e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GBEEKLPO_01308 8e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GBEEKLPO_01309 2.2e-41 pspC KT PspC domain
GBEEKLPO_01310 0.0 yhgF K Transcriptional accessory protein
GBEEKLPO_01312 4.9e-157 XK27_03015 S permease
GBEEKLPO_01313 1.7e-148 ycgQ S TIGR03943 family
GBEEKLPO_01314 4e-290 sulP P Sulfate permease and related transporters (MFS superfamily)
GBEEKLPO_01315 7.3e-104
GBEEKLPO_01316 2.5e-123 estA E GDSL-like Lipase/Acylhydrolase
GBEEKLPO_01317 1.1e-99 S CAAX protease self-immunity
GBEEKLPO_01318 8.8e-57
GBEEKLPO_01320 2.7e-66 yqeB S Pyrimidine dimer DNA glycosylase
GBEEKLPO_01321 4.1e-60 S Protein of unknown function (DUF1722)
GBEEKLPO_01322 6.5e-19 M Bacterial lipoprotein
GBEEKLPO_01323 1.5e-10
GBEEKLPO_01324 7.7e-132 V CAAX protease self-immunity
GBEEKLPO_01325 5.8e-49
GBEEKLPO_01326 5.5e-132 ybbA S Putative esterase
GBEEKLPO_01327 4.7e-172 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
GBEEKLPO_01328 1.1e-136 fecE 3.6.3.34 HP ABC transporter
GBEEKLPO_01329 4.8e-156 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GBEEKLPO_01330 1.7e-131 V CAAX protease self-immunity
GBEEKLPO_01331 1.6e-157 S Domain of unknown function (DUF4300)
GBEEKLPO_01332 1.9e-95 tetR K transcriptional regulator
GBEEKLPO_01333 2.7e-300 norB P Major facilitator superfamily
GBEEKLPO_01334 2.5e-61 tnp* L An automated process has identified a potential problem with this gene model
GBEEKLPO_01335 1.7e-201 L Transposase
GBEEKLPO_01336 0.0 M family 8
GBEEKLPO_01337 3.3e-115 cutC P Participates in the control of copper homeostasis
GBEEKLPO_01338 2.3e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
GBEEKLPO_01339 1.6e-154 yitS S EDD domain protein, DegV family
GBEEKLPO_01340 3e-207 yeaN P transporter
GBEEKLPO_01341 1.6e-148 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GBEEKLPO_01342 8.5e-162 K Helix-turn-helix XRE-family like proteins
GBEEKLPO_01343 9.6e-141 S CAAX protease self-immunity
GBEEKLPO_01344 2e-140 S Alpha beta hydrolase
GBEEKLPO_01345 4.2e-65
GBEEKLPO_01346 3.8e-54 D Plasmid stabilization system
GBEEKLPO_01347 9.7e-46
GBEEKLPO_01348 8e-148 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GBEEKLPO_01349 2e-58 S ParE toxin of type II toxin-antitoxin system, parDE
GBEEKLPO_01350 4.8e-45
GBEEKLPO_01351 0.0 O Molecular chaperone. Has ATPase activity
GBEEKLPO_01352 1.3e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GBEEKLPO_01353 2e-97 mip S hydroperoxide reductase activity
GBEEKLPO_01354 2.4e-203 I acyl-CoA dehydrogenase
GBEEKLPO_01355 1e-157 ydiA P C4-dicarboxylate transporter malic acid transport
GBEEKLPO_01356 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GBEEKLPO_01357 2.4e-113 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GBEEKLPO_01358 2.7e-236 ulaA 2.7.1.194 S protein conserved in bacteria
GBEEKLPO_01359 5.8e-46 ulaB 2.7.1.194 G Phosphotransferase system galactitol-specific IIB component
GBEEKLPO_01360 4.7e-76 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
GBEEKLPO_01361 4.6e-12 manR 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
GBEEKLPO_01362 1.2e-256 manR K PRD domain
GBEEKLPO_01363 1.3e-249 msrR K Transcriptional regulator
GBEEKLPO_01364 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
GBEEKLPO_01365 4.5e-80 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GBEEKLPO_01366 7.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GBEEKLPO_01367 5.1e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GBEEKLPO_01368 4.2e-53 yheA S Belongs to the UPF0342 family
GBEEKLPO_01369 8.3e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
GBEEKLPO_01370 5.8e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GBEEKLPO_01371 1.6e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GBEEKLPO_01372 3.1e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GBEEKLPO_01373 7.3e-121 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GBEEKLPO_01374 3.1e-220 ywbD 2.1.1.191 J Methyltransferase
GBEEKLPO_01375 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GBEEKLPO_01376 1.2e-25 WQ51_00785
GBEEKLPO_01377 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GBEEKLPO_01378 7.9e-79 yueI S Protein of unknown function (DUF1694)
GBEEKLPO_01379 4.7e-282 L Transposase
GBEEKLPO_01380 1.6e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GBEEKLPO_01381 2e-205 yyaQ S YjbR
GBEEKLPO_01382 1.3e-182 ccpA K Catabolite control protein A
GBEEKLPO_01383 1.6e-210 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
GBEEKLPO_01384 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
GBEEKLPO_01385 1.5e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GBEEKLPO_01386 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GBEEKLPO_01387 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GBEEKLPO_01388 2e-33 secG U Preprotein translocase subunit SecG
GBEEKLPO_01389 6.3e-224 mdtG EGP Major facilitator Superfamily
GBEEKLPO_01390 2.1e-103 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GBEEKLPO_01391 9.3e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GBEEKLPO_01392 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GBEEKLPO_01393 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GBEEKLPO_01394 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GBEEKLPO_01395 8.1e-154 licT K antiterminator
GBEEKLPO_01396 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GBEEKLPO_01397 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
GBEEKLPO_01398 8.3e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GBEEKLPO_01399 1.4e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GBEEKLPO_01400 1.6e-151 I Alpha/beta hydrolase family
GBEEKLPO_01401 6.6e-08
GBEEKLPO_01402 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
GBEEKLPO_01403 1.4e-78 feoA P FeoA domain protein
GBEEKLPO_01404 1.9e-88 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_01405 1.3e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
GBEEKLPO_01406 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
GBEEKLPO_01407 1e-34 ykuJ S protein conserved in bacteria
GBEEKLPO_01408 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GBEEKLPO_01409 0.0 clpE O Belongs to the ClpA ClpB family
GBEEKLPO_01410 7.9e-87 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
GBEEKLPO_01411 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
GBEEKLPO_01412 4.6e-177 S oxidoreductase
GBEEKLPO_01413 4.4e-118 M Pfam SNARE associated Golgi protein
GBEEKLPO_01414 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
GBEEKLPO_01417 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
GBEEKLPO_01420 4.8e-16 S Protein of unknown function (DUF2969)
GBEEKLPO_01421 4.8e-201 ilvE 2.6.1.42 E Aminotransferase
GBEEKLPO_01422 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GBEEKLPO_01423 1.1e-10
GBEEKLPO_01425 3.2e-127
GBEEKLPO_01426 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GBEEKLPO_01427 1.8e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GBEEKLPO_01428 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
GBEEKLPO_01429 2.2e-30 S Domain of unknown function (DUF1912)
GBEEKLPO_01430 1.1e-178 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
GBEEKLPO_01431 1.8e-251 mmuP E amino acid
GBEEKLPO_01432 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
GBEEKLPO_01433 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GBEEKLPO_01434 9.7e-22
GBEEKLPO_01435 9.6e-94 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GBEEKLPO_01436 5.9e-168 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GBEEKLPO_01437 7.9e-216 mvaS 2.3.3.10 I synthase
GBEEKLPO_01438 4.7e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GBEEKLPO_01439 3e-78 K hmm pf08876
GBEEKLPO_01440 5.2e-119 yqfA K protein, Hemolysin III
GBEEKLPO_01441 4.1e-29 pspC KT PspC domain protein
GBEEKLPO_01442 3.9e-206 S Protein of unknown function (DUF3114)
GBEEKLPO_01443 1.8e-170 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GBEEKLPO_01444 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GBEEKLPO_01445 4e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
GBEEKLPO_01446 2.3e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
GBEEKLPO_01447 0.0 U protein secretion
GBEEKLPO_01448 1.2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GBEEKLPO_01449 2e-26
GBEEKLPO_01450 5.9e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
GBEEKLPO_01451 1.3e-257 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GBEEKLPO_01452 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
GBEEKLPO_01453 7.1e-50 S ABC-2 family transporter protein
GBEEKLPO_01454 6.8e-153 V ABC transporter, ATP-binding protein
GBEEKLPO_01455 4.4e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GBEEKLPO_01456 7.8e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GBEEKLPO_01457 1.6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GBEEKLPO_01458 4.8e-157 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
GBEEKLPO_01459 1e-104 GBS0088 J protein conserved in bacteria
GBEEKLPO_01460 1.4e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GBEEKLPO_01461 1e-145 E Alpha beta hydrolase
GBEEKLPO_01463 4e-201 ald 1.4.1.1 C Belongs to the AlaDH PNT family
GBEEKLPO_01464 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GBEEKLPO_01465 2.7e-143 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GBEEKLPO_01466 1.7e-114 S VIT family
GBEEKLPO_01467 6.3e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
GBEEKLPO_01468 1.6e-24
GBEEKLPO_01469 1.9e-29 XK27_00085 K Transcriptional
GBEEKLPO_01470 1.8e-197 yceA S Belongs to the UPF0176 family
GBEEKLPO_01471 8.8e-54 S Protein conserved in bacteria
GBEEKLPO_01472 1.5e-124 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GBEEKLPO_01473 1.2e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GBEEKLPO_01474 0.0 lmrA V abc transporter atp-binding protein
GBEEKLPO_01475 0.0 mdlB V abc transporter atp-binding protein
GBEEKLPO_01476 4.6e-29 K DNA-binding transcription factor activity
GBEEKLPO_01477 2.2e-274 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
GBEEKLPO_01479 7.6e-48 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GBEEKLPO_01480 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GBEEKLPO_01481 3.6e-203 V permease protein
GBEEKLPO_01482 4.3e-124 macB V ABC transporter, ATP-binding protein
GBEEKLPO_01483 1.7e-184 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GBEEKLPO_01484 2.9e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
GBEEKLPO_01485 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
GBEEKLPO_01486 8.4e-212 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
GBEEKLPO_01487 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GBEEKLPO_01488 1.2e-222 pyrP F uracil Permease
GBEEKLPO_01489 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GBEEKLPO_01490 2.2e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GBEEKLPO_01491 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GBEEKLPO_01492 4.7e-168 fhuR K transcriptional regulator (lysR family)
GBEEKLPO_01494 5.1e-73 K Helix-turn-helix
GBEEKLPO_01496 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GBEEKLPO_01497 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GBEEKLPO_01498 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
GBEEKLPO_01499 1.2e-255 cycA E permease
GBEEKLPO_01500 2e-39 ynzC S UPF0291 protein
GBEEKLPO_01501 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GBEEKLPO_01502 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GBEEKLPO_01503 2.5e-67 S Glutathione-dependent formaldehyde-activating
GBEEKLPO_01504 5.4e-223 S membrane
GBEEKLPO_01505 1e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GBEEKLPO_01506 2e-294 nptA P COG1283 Na phosphate symporter
GBEEKLPO_01507 2e-117 3.4.17.14, 3.5.1.28 NU amidase activity
GBEEKLPO_01508 2.3e-85 S Bacterial inner membrane protein
GBEEKLPO_01509 7e-147 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
GBEEKLPO_01510 1.7e-108 S HD domain
GBEEKLPO_01511 5.4e-105 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
GBEEKLPO_01512 1.9e-53 glnB K Belongs to the P(II) protein family
GBEEKLPO_01513 1.2e-230 amt P Ammonium Transporter
GBEEKLPO_01514 1.3e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GBEEKLPO_01515 1.2e-54 yabA L Involved in initiation control of chromosome replication
GBEEKLPO_01516 8.6e-137 yaaT S stage 0 sporulation protein
GBEEKLPO_01517 3.2e-161 holB 2.7.7.7 L dna polymerase iii
GBEEKLPO_01518 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GBEEKLPO_01520 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GBEEKLPO_01521 2.6e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GBEEKLPO_01522 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GBEEKLPO_01523 5.1e-216 ftsW D Belongs to the SEDS family
GBEEKLPO_01524 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GBEEKLPO_01525 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GBEEKLPO_01526 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GBEEKLPO_01527 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GBEEKLPO_01528 4.6e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GBEEKLPO_01529 9.5e-78 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GBEEKLPO_01530 2.8e-123 atpB C it plays a direct role in the translocation of protons across the membrane
GBEEKLPO_01531 5.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GBEEKLPO_01532 1.6e-187 femA 2.3.2.10, 2.3.2.16 V FemAB family
GBEEKLPO_01534 4.9e-60 arsC 1.20.4.1 P Belongs to the ArsC family
GBEEKLPO_01535 2.8e-22 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
GBEEKLPO_01536 1.5e-228 L Transposase
GBEEKLPO_01537 5.4e-156 rarD S Transporter
GBEEKLPO_01538 1.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GBEEKLPO_01539 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
GBEEKLPO_01540 6.9e-140 yxkH G deacetylase
GBEEKLPO_01541 4.8e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
GBEEKLPO_01542 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
GBEEKLPO_01543 4.6e-219 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GBEEKLPO_01544 5.9e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GBEEKLPO_01545 2.4e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
GBEEKLPO_01546 1.3e-142 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GBEEKLPO_01547 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
GBEEKLPO_01549 3e-232 2.7.13.3 T GHKL domain
GBEEKLPO_01550 5.6e-135 agrA KT response regulator
GBEEKLPO_01551 3.1e-07
GBEEKLPO_01552 4.3e-138 agrA KT response regulator
GBEEKLPO_01553 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
GBEEKLPO_01555 1.2e-09
GBEEKLPO_01556 6.1e-64 K sequence-specific DNA binding
GBEEKLPO_01557 5.2e-77 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_01559 2.6e-135 agrA KT Response regulator of the LytR AlgR family
GBEEKLPO_01560 3.2e-234 2.7.13.3 T GHKL domain
GBEEKLPO_01562 8.5e-120
GBEEKLPO_01563 1.8e-116 V ATPases associated with a variety of cellular activities
GBEEKLPO_01572 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GBEEKLPO_01573 7.8e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
GBEEKLPO_01574 1.9e-127 yrrM 2.1.1.104 S O-Methyltransferase
GBEEKLPO_01575 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
GBEEKLPO_01576 0.0 pepF E oligoendopeptidase F
GBEEKLPO_01577 3.5e-185 coiA 3.6.4.12 S Competence protein
GBEEKLPO_01578 5.2e-78 L transposition
GBEEKLPO_01579 1.3e-55 insK L Integrase core domain protein
GBEEKLPO_01580 7.3e-163 S CHAP domain
GBEEKLPO_01581 1.7e-308 S Glucan-binding protein C
GBEEKLPO_01582 2.7e-105 S CAAX amino terminal protease family protein
GBEEKLPO_01583 4.7e-168 K transcriptional regulator (lysR family)
GBEEKLPO_01584 9.6e-163 S reductase
GBEEKLPO_01585 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GBEEKLPO_01590 2.8e-191 phoH T phosphate starvation-inducible protein PhoH
GBEEKLPO_01591 6e-137 sip M LysM domain protein
GBEEKLPO_01592 3.7e-34 yozE S Belongs to the UPF0346 family
GBEEKLPO_01593 5.3e-161 cvfB S Protein conserved in bacteria
GBEEKLPO_01594 1.7e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GBEEKLPO_01595 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GBEEKLPO_01596 3.6e-219 sptS 2.7.13.3 T Histidine kinase
GBEEKLPO_01597 4.4e-118 T response regulator
GBEEKLPO_01598 7.2e-115 2.7.6.5 S Region found in RelA / SpoT proteins
GBEEKLPO_01599 3.2e-115 K Acetyltransferase (GNAT) family
GBEEKLPO_01600 0.0 lmrA2 V abc transporter atp-binding protein
GBEEKLPO_01601 0.0 lmrA1 V abc transporter atp-binding protein
GBEEKLPO_01602 3.3e-74 K DNA-binding transcription factor activity
GBEEKLPO_01603 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GBEEKLPO_01604 5.4e-287 S Psort location CytoplasmicMembrane, score
GBEEKLPO_01605 2.8e-257 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
GBEEKLPO_01606 6.3e-215 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
GBEEKLPO_01607 1.4e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
GBEEKLPO_01608 1.7e-26 U response to pH
GBEEKLPO_01609 0.0 yfmR S abc transporter atp-binding protein
GBEEKLPO_01610 2e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GBEEKLPO_01611 1.3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GBEEKLPO_01612 2.9e-151 XK27_08360 S EDD domain protein, DegV family
GBEEKLPO_01613 5e-63 WQ51_03320 S cog cog4835
GBEEKLPO_01614 4.5e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GBEEKLPO_01615 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GBEEKLPO_01616 3.4e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
GBEEKLPO_01617 5.8e-97 2.3.1.128 K acetyltransferase
GBEEKLPO_01618 2.1e-257 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GBEEKLPO_01619 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GBEEKLPO_01620 1.7e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GBEEKLPO_01621 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
GBEEKLPO_01623 1.2e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GBEEKLPO_01624 1.1e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GBEEKLPO_01625 0.0 fruA 2.7.1.202 G phosphotransferase system
GBEEKLPO_01626 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GBEEKLPO_01627 7.3e-114 fruR K transcriptional
GBEEKLPO_01628 2.4e-207 rny D Endoribonuclease that initiates mRNA decay
GBEEKLPO_01629 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GBEEKLPO_01630 1.8e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GBEEKLPO_01631 2.7e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GBEEKLPO_01632 2.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GBEEKLPO_01633 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GBEEKLPO_01634 5.6e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GBEEKLPO_01635 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GBEEKLPO_01636 1.1e-125 IQ reductase
GBEEKLPO_01637 1.5e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
GBEEKLPO_01638 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
GBEEKLPO_01639 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBEEKLPO_01640 6.8e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GBEEKLPO_01641 5.2e-72 marR K Transcriptional regulator, MarR family
GBEEKLPO_01642 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
GBEEKLPO_01643 1.6e-117 S HAD hydrolase, family IA, variant 3
GBEEKLPO_01644 1.3e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
GBEEKLPO_01645 1.4e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
GBEEKLPO_01646 4.3e-250 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GBEEKLPO_01647 2e-138 recX 2.4.1.337 GT4 S Regulatory protein RecX
GBEEKLPO_01648 7.8e-102 ygaC J Belongs to the UPF0374 family
GBEEKLPO_01649 1.4e-107 S Domain of unknown function (DUF1803)
GBEEKLPO_01650 9.2e-167 ppaC 3.6.1.1 C inorganic pyrophosphatase
GBEEKLPO_01658 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GBEEKLPO_01659 3.1e-84 comFC S Competence protein
GBEEKLPO_01660 5.7e-255 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GBEEKLPO_01661 2.4e-110 yvyE 3.4.13.9 S YigZ family
GBEEKLPO_01662 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GBEEKLPO_01663 5.4e-113 acuB S CBS domain
GBEEKLPO_01664 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
GBEEKLPO_01665 2.8e-137 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
GBEEKLPO_01666 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
GBEEKLPO_01667 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
GBEEKLPO_01668 1.7e-213 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
GBEEKLPO_01669 1.9e-46 ylbG S UPF0298 protein
GBEEKLPO_01670 3e-72 ylbF S Belongs to the UPF0342 family
GBEEKLPO_01671 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GBEEKLPO_01672 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GBEEKLPO_01673 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
GBEEKLPO_01674 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
GBEEKLPO_01675 5.4e-225 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GBEEKLPO_01676 3.6e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
GBEEKLPO_01677 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
GBEEKLPO_01678 2.7e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
GBEEKLPO_01679 3.8e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GBEEKLPO_01680 1.4e-101 yvdD 3.2.2.10 S Belongs to the LOG family
GBEEKLPO_01681 1.3e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GBEEKLPO_01682 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GBEEKLPO_01683 8e-42 ylxQ J ribosomal protein
GBEEKLPO_01684 2.7e-48 ylxR K Nucleic-acid-binding protein implicated in transcription termination
GBEEKLPO_01685 2.4e-196 nusA K Participates in both transcription termination and antitermination
GBEEKLPO_01686 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
GBEEKLPO_01687 6.7e-213 brpA K Transcriptional
GBEEKLPO_01688 2.4e-92 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
GBEEKLPO_01689 8.5e-78 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
GBEEKLPO_01690 2.5e-248 pbuO S permease
GBEEKLPO_01691 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
GBEEKLPO_01692 7.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
GBEEKLPO_01693 1.6e-169 manL 2.7.1.191 G pts system
GBEEKLPO_01694 4.7e-135 manY G pts system
GBEEKLPO_01695 1.9e-164 manN G PTS system mannose fructose sorbose family IID component
GBEEKLPO_01696 2e-67 manO S Protein conserved in bacteria
GBEEKLPO_01697 4.9e-174 manL 2.7.1.191 G pts system
GBEEKLPO_01698 2.6e-117 manM G pts system
GBEEKLPO_01699 2.5e-169 manN G PTS system mannose fructose sorbose family IID component
GBEEKLPO_01700 2.5e-62 manO S protein conserved in bacteria
GBEEKLPO_01701 5.6e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GBEEKLPO_01702 2.5e-115
GBEEKLPO_01703 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GBEEKLPO_01704 1.5e-166 dnaI L Primosomal protein DnaI
GBEEKLPO_01705 1.6e-216 dnaB L Replication initiation and membrane attachment
GBEEKLPO_01706 1.6e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GBEEKLPO_01707 9.8e-283 T PhoQ Sensor
GBEEKLPO_01708 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GBEEKLPO_01709 2.8e-91 yceD K metal-binding, possibly nucleic acid-binding protein
GBEEKLPO_01710 8.1e-131 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
GBEEKLPO_01711 1e-238 P COG0168 Trk-type K transport systems, membrane components
GBEEKLPO_01712 4.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
GBEEKLPO_01713 2e-149 cbiQ P cobalt transport
GBEEKLPO_01714 0.0 ykoD P abc transporter atp-binding protein
GBEEKLPO_01715 8e-94 S UPF0397 protein
GBEEKLPO_01716 4.2e-155 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
GBEEKLPO_01717 1.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GBEEKLPO_01718 1.2e-99 metI P ABC transporter (Permease
GBEEKLPO_01719 7.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GBEEKLPO_01720 9.1e-264 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
GBEEKLPO_01721 1.4e-164 metQ M Belongs to the NlpA lipoprotein family
GBEEKLPO_01722 6.3e-138 ET ABC transporter substrate-binding protein
GBEEKLPO_01723 2.8e-131 cbiO P ABC transporter
GBEEKLPO_01724 7.5e-138 P cobalt transport protein
GBEEKLPO_01725 2.1e-177 cbiM P PDGLE domain
GBEEKLPO_01726 1.4e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GBEEKLPO_01727 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GBEEKLPO_01728 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GBEEKLPO_01729 6.6e-78 ureE O enzyme active site formation
GBEEKLPO_01730 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GBEEKLPO_01731 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
GBEEKLPO_01732 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
GBEEKLPO_01733 6.8e-95 ureI S AmiS/UreI family transporter
GBEEKLPO_01734 1.2e-255 S Domain of unknown function (DUF4173)
GBEEKLPO_01735 1.2e-55 yhaI L Membrane
GBEEKLPO_01736 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GBEEKLPO_01737 1.9e-153 K sequence-specific DNA binding
GBEEKLPO_01738 2.8e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
GBEEKLPO_01739 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GBEEKLPO_01740 6.1e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GBEEKLPO_01741 1.2e-247 trkA P Potassium transporter peripheral membrane component
GBEEKLPO_01742 4.9e-260 trkH P Cation transport protein
GBEEKLPO_01743 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
GBEEKLPO_01744 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GBEEKLPO_01745 6.5e-94 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GBEEKLPO_01746 1.8e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GBEEKLPO_01747 1e-134 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
GBEEKLPO_01748 8.3e-87 ykuL S CBS domain
GBEEKLPO_01749 1.7e-98 XK27_09740 S Phosphoesterase
GBEEKLPO_01750 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GBEEKLPO_01751 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GBEEKLPO_01752 1.6e-36 yneF S UPF0154 protein
GBEEKLPO_01753 1.4e-90 K transcriptional regulator
GBEEKLPO_01754 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GBEEKLPO_01755 8.4e-13 ycdA S Domain of unknown function (DUF4352)
GBEEKLPO_01756 6.9e-103 ybhL S Belongs to the BI1 family
GBEEKLPO_01757 2.5e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
GBEEKLPO_01758 5.5e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GBEEKLPO_01759 9.2e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GBEEKLPO_01760 3.4e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GBEEKLPO_01761 3e-237 L Transposase
GBEEKLPO_01762 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GBEEKLPO_01763 2.1e-306 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GBEEKLPO_01764 4.1e-89 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
GBEEKLPO_01765 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GBEEKLPO_01766 9.6e-23
GBEEKLPO_01767 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
GBEEKLPO_01768 1.1e-286 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
GBEEKLPO_01769 1.3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GBEEKLPO_01770 1.1e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GBEEKLPO_01771 8e-96 ypsA S Belongs to the UPF0398 family
GBEEKLPO_01772 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GBEEKLPO_01773 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GBEEKLPO_01774 2.3e-65 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_01775 4.3e-258 pepC 3.4.22.40 E aminopeptidase
GBEEKLPO_01776 1.1e-77 yhaI S Protein of unknown function (DUF805)
GBEEKLPO_01777 1.4e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GBEEKLPO_01778 1.9e-267 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GBEEKLPO_01779 5.3e-221 macB_2 V FtsX-like permease family
GBEEKLPO_01780 3.5e-123 yhcA V abc transporter atp-binding protein
GBEEKLPO_01781 4.6e-126 mta K Transcriptional
GBEEKLPO_01782 4.4e-31 S Protein of unknown function (DUF3021)
GBEEKLPO_01783 9e-75 K COG3279 Response regulator of the LytR AlgR family
GBEEKLPO_01784 2.8e-130 cylB V ABC-2 type transporter
GBEEKLPO_01785 1.9e-158 cylA V abc transporter atp-binding protein
GBEEKLPO_01786 1.2e-25 yjdF S Protein of unknown function (DUF2992)
GBEEKLPO_01787 1.4e-239 S COG1073 Hydrolases of the alpha beta superfamily
GBEEKLPO_01788 9.6e-77 K transcriptional
GBEEKLPO_01789 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GBEEKLPO_01790 4.8e-137 glcR K transcriptional regulator (DeoR family)
GBEEKLPO_01791 5.8e-149 cof S Sucrose-6F-phosphate phosphohydrolase
GBEEKLPO_01792 2.4e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
GBEEKLPO_01793 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
GBEEKLPO_01794 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
GBEEKLPO_01795 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GBEEKLPO_01796 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GBEEKLPO_01797 5.6e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GBEEKLPO_01798 5.8e-55 S TM2 domain
GBEEKLPO_01799 5.5e-44
GBEEKLPO_01801 8.2e-288 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GBEEKLPO_01802 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GBEEKLPO_01803 1.4e-142 cmpC S abc transporter atp-binding protein
GBEEKLPO_01804 0.0 WQ51_06230 S ABC transporter
GBEEKLPO_01805 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GBEEKLPO_01806 5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GBEEKLPO_01807 8.5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
GBEEKLPO_01808 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GBEEKLPO_01809 3.1e-48 yajC U protein transport
GBEEKLPO_01810 9.4e-127 yeeN K transcriptional regulatory protein
GBEEKLPO_01811 4.8e-285 V ABC transporter
GBEEKLPO_01812 2.2e-154 Z012_04635 K sequence-specific DNA binding
GBEEKLPO_01813 1.6e-257 pgi 5.3.1.9 G Belongs to the GPI family
GBEEKLPO_01814 1.4e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
GBEEKLPO_01815 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GBEEKLPO_01816 6.2e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
GBEEKLPO_01817 2.7e-130 adcB P ABC transporter (Permease
GBEEKLPO_01818 2.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
GBEEKLPO_01819 1.2e-71 adcR K transcriptional
GBEEKLPO_01820 1.1e-181 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GBEEKLPO_01821 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GBEEKLPO_01822 8e-26
GBEEKLPO_01823 3e-237 L Transposase
GBEEKLPO_01824 1.5e-169 oppF P Belongs to the ABC transporter superfamily
GBEEKLPO_01825 6.6e-198 oppD P Belongs to the ABC transporter superfamily
GBEEKLPO_01826 1.9e-165 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBEEKLPO_01827 9.7e-161 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
GBEEKLPO_01828 2.3e-311 oppA E ABC transporter substrate-binding protein
GBEEKLPO_01829 1e-273 sufB O assembly protein SufB
GBEEKLPO_01830 2.3e-72 nifU C SUF system FeS assembly protein, NifU family
GBEEKLPO_01831 1.6e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GBEEKLPO_01832 6.3e-235 sufD O assembly protein SufD
GBEEKLPO_01833 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GBEEKLPO_01834 1e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
GBEEKLPO_01835 2.3e-128 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GBEEKLPO_01836 4.4e-19 S Protein of unknown function (DUF3021)
GBEEKLPO_01837 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GBEEKLPO_01838 6.9e-276 glnP P ABC transporter
GBEEKLPO_01839 2.2e-123 glnQ E abc transporter atp-binding protein
GBEEKLPO_01840 3.4e-187 D nuclear chromosome segregation
GBEEKLPO_01841 9.5e-85 V VanZ like family
GBEEKLPO_01842 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GBEEKLPO_01843 9.6e-198 yhjX P Major Facilitator
GBEEKLPO_01844 3.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
GBEEKLPO_01845 2.5e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GBEEKLPO_01846 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GBEEKLPO_01847 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
GBEEKLPO_01848 4.7e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GBEEKLPO_01849 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GBEEKLPO_01850 1.1e-83 nrdI F Belongs to the NrdI family
GBEEKLPO_01851 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
GBEEKLPO_01852 2.8e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GBEEKLPO_01853 7e-178 prmA J Ribosomal protein L11 methyltransferase
GBEEKLPO_01854 1.8e-92 XK27_02675 K Acetyltransferase GNAT Family
GBEEKLPO_01855 2.2e-78 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
GBEEKLPO_01856 3.8e-84 XK27_03960 S Protein of unknown function (DUF3013)
GBEEKLPO_01857 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GBEEKLPO_01858 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GBEEKLPO_01859 4.7e-230 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GBEEKLPO_01860 2.8e-140 ykuT M mechanosensitive ion channel
GBEEKLPO_01861 5.9e-88 sigH K DNA-templated transcription, initiation
GBEEKLPO_01862 1.9e-88 L COG1943 Transposase and inactivated derivatives
GBEEKLPO_01875 1.5e-80 hmpT S cog cog4720
GBEEKLPO_01876 7.3e-138 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
GBEEKLPO_01877 1.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GBEEKLPO_01878 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GBEEKLPO_01879 1.1e-30
GBEEKLPO_01880 2.3e-299 dnaK O Heat shock 70 kDa protein
GBEEKLPO_01881 5.7e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GBEEKLPO_01882 4.1e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GBEEKLPO_01883 3.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
GBEEKLPO_01884 2.3e-142 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
GBEEKLPO_01885 5.6e-132 ais G Phosphoglycerate mutase
GBEEKLPO_01886 1.7e-243 XK27_08635 S UPF0210 protein
GBEEKLPO_01887 6.1e-39 gcvR T UPF0237 protein
GBEEKLPO_01888 2.3e-234 capA M Bacterial capsule synthesis protein
GBEEKLPO_01889 8.5e-140 srtB 3.4.22.70 S sortase, SrtB family
GBEEKLPO_01890 6e-85
GBEEKLPO_01891 1.5e-29 K Helix-turn-helix domain
GBEEKLPO_01892 3.4e-18
GBEEKLPO_01893 6.4e-93 L Transposase
GBEEKLPO_01894 6.7e-89 H Methyltransferase
GBEEKLPO_01895 1.7e-89 S Protein conserved in bacteria
GBEEKLPO_01896 1.4e-50 yiiE S protein homotetramerization
GBEEKLPO_01897 1.6e-16
GBEEKLPO_01898 4.5e-55 cadX K transcriptional regulator, ArsR family
GBEEKLPO_01899 3.4e-101 cadD P cadmium resistance
GBEEKLPO_01901 0.0 3.6.3.4 P P-type ATPase
GBEEKLPO_01902 4.9e-81 copY K Copper transport repressor, CopY TcrY family
GBEEKLPO_01903 4.6e-193 L PFAM Integrase, catalytic core
GBEEKLPO_01904 7.3e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
GBEEKLPO_01905 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GBEEKLPO_01906 5.1e-22 K Transcriptional
GBEEKLPO_01908 1.4e-153 degV S DegV family
GBEEKLPO_01909 2.7e-91 yacP S RNA-binding protein containing a PIN domain
GBEEKLPO_01910 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GBEEKLPO_01912 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GBEEKLPO_01913 8.1e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GBEEKLPO_01915 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
GBEEKLPO_01916 1.7e-142 S SseB protein N-terminal domain
GBEEKLPO_01917 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GBEEKLPO_01918 6e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GBEEKLPO_01919 2e-233 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GBEEKLPO_01920 0.0 clpC O Belongs to the ClpA ClpB family
GBEEKLPO_01921 4.8e-76 ctsR K Belongs to the CtsR family
GBEEKLPO_01922 1.2e-82 S Putative small multi-drug export protein
GBEEKLPO_01923 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GBEEKLPO_01924 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
GBEEKLPO_01925 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
GBEEKLPO_01926 8.3e-290 ahpF O alkyl hydroperoxide reductase
GBEEKLPO_01928 3.8e-96 S reductase
GBEEKLPO_01929 3.9e-72 badR K Transcriptional regulator, marr family
GBEEKLPO_01930 5.5e-36 XK27_02060 S Transglycosylase associated protein
GBEEKLPO_01931 3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
GBEEKLPO_01932 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GBEEKLPO_01937 1.9e-07
GBEEKLPO_01940 2.6e-10
GBEEKLPO_01946 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
GBEEKLPO_01947 2.1e-193 L PFAM Integrase, catalytic core
GBEEKLPO_01948 6.1e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GBEEKLPO_01949 7.7e-233 cinA 3.5.1.42 S Belongs to the CinA family
GBEEKLPO_01950 2.2e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
GBEEKLPO_01951 2e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GBEEKLPO_01953 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GBEEKLPO_01955 1.8e-72 K LytTr DNA-binding domain
GBEEKLPO_01956 4.2e-80 S Protein of unknown function (DUF3021)
GBEEKLPO_01957 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GBEEKLPO_01958 7.9e-58 ymcA 3.6.3.21 S Belongs to the UPF0342 family
GBEEKLPO_01959 6.3e-70 argR K Regulates arginine biosynthesis genes
GBEEKLPO_01960 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GBEEKLPO_01961 2.7e-193 L PFAM Integrase, catalytic core
GBEEKLPO_01964 2.1e-12
GBEEKLPO_01965 1.1e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GBEEKLPO_01967 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GBEEKLPO_01968 9e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GBEEKLPO_01969 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
GBEEKLPO_01970 2.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GBEEKLPO_01971 6.8e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GBEEKLPO_01972 1.4e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GBEEKLPO_01973 1.2e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GBEEKLPO_01974 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GBEEKLPO_01975 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GBEEKLPO_01976 6.2e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GBEEKLPO_01977 1.9e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GBEEKLPO_01978 3.1e-144 recO L Involved in DNA repair and RecF pathway recombination
GBEEKLPO_01979 3.8e-218 araT 2.6.1.1 E Aminotransferase
GBEEKLPO_01980 1.1e-13 L PFAM transposase IS116 IS110 IS902 family
GBEEKLPO_01981 7.9e-79 L PFAM transposase IS116 IS110 IS902 family
GBEEKLPO_01982 3.2e-65 L Transposase (IS116 IS110 IS902 family)
GBEEKLPO_01983 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GBEEKLPO_01984 3.3e-91 usp 3.5.1.28 CBM50 S CHAP domain
GBEEKLPO_01985 1.9e-84 mreD M rod shape-determining protein MreD
GBEEKLPO_01986 1.2e-106 mreC M Involved in formation and maintenance of cell shape
GBEEKLPO_01992 2.6e-10
GBEEKLPO_02005 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GBEEKLPO_02006 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GBEEKLPO_02007 1.4e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GBEEKLPO_02008 1.3e-238 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
GBEEKLPO_02010 3e-60 divIC D Septum formation initiator
GBEEKLPO_02011 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GBEEKLPO_02012 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GBEEKLPO_02013 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GBEEKLPO_02014 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GBEEKLPO_02015 1.1e-29 yyzM S Protein conserved in bacteria
GBEEKLPO_02016 2.4e-122 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GBEEKLPO_02017 0.0 S peptidoglycan catabolic process
GBEEKLPO_02018 2.9e-266
GBEEKLPO_02019 8.4e-12
GBEEKLPO_02020 5.1e-72 S Pfam:Phage_holin_4_1
GBEEKLPO_02021 1.1e-23 S COG5546 Small integral membrane protein
GBEEKLPO_02022 1.5e-143 S peptidoglycan catabolic process
GBEEKLPO_02024 2.3e-10
GBEEKLPO_02025 1.5e-200 S Phage integrase family
GBEEKLPO_02027 6.7e-20 E Zn peptidase
GBEEKLPO_02028 2e-21
GBEEKLPO_02029 4.4e-29
GBEEKLPO_02032 6.9e-133 S DNA binding
GBEEKLPO_02035 7.4e-61 M Pilin isopeptide linkage domain protein
GBEEKLPO_02037 2.2e-79 S Siphovirus Gp157
GBEEKLPO_02038 2.9e-120 S AAA domain
GBEEKLPO_02039 8.4e-262 S helicase activity
GBEEKLPO_02040 1.8e-57 S Protein of unknown function (DUF669)
GBEEKLPO_02041 6.3e-135 S Primase C terminal 1 (PriCT-1)
GBEEKLPO_02042 6.4e-306 S hydrolase activity
GBEEKLPO_02043 1.8e-48 S hydrolase activity, acting on ester bonds
GBEEKLPO_02050 4.4e-22 S YopX protein
GBEEKLPO_02052 1.1e-12 S Protein of unknown function (DUF1492)
GBEEKLPO_02053 2.9e-85 S peptidase activity
GBEEKLPO_02054 9.5e-64 L phage terminase small subunit
GBEEKLPO_02056 1.6e-176 S regulation of transcription, DNA-dependent
GBEEKLPO_02057 1e-82 S Phage Terminase
GBEEKLPO_02058 1.4e-191 S Phage Terminase
GBEEKLPO_02060 5.1e-199 S Phage portal protein
GBEEKLPO_02061 1.8e-116 S Clp protease
GBEEKLPO_02062 8.1e-200 S peptidase activity
GBEEKLPO_02063 1.5e-49 S Phage gp6-like head-tail connector protein
GBEEKLPO_02064 1.5e-61 S Phage head-tail joining protein
GBEEKLPO_02065 8e-65 S exonuclease activity
GBEEKLPO_02066 5.9e-56 S Protein of unknown function (DUF806)
GBEEKLPO_02067 4.8e-111 S Pfam:Phage_TTP_1
GBEEKLPO_02069 5.5e-245 S peptidoglycan catabolic process
GBEEKLPO_02070 0.0 S peptidoglycan catabolic process
GBEEKLPO_02071 3.3e-241 S Phage tail protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)