ORF_ID e_value Gene_name EC_number CAZy COGs Description
OLEDPIAI_00001 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
OLEDPIAI_00002 3.4e-94 M1-753 M FR47-like protein
OLEDPIAI_00003 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
OLEDPIAI_00004 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
OLEDPIAI_00005 3.9e-84 yuaE S DinB superfamily
OLEDPIAI_00006 7.9e-108 yuaD
OLEDPIAI_00007 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
OLEDPIAI_00008 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
OLEDPIAI_00009 1.1e-95 yuaC K Belongs to the GbsR family
OLEDPIAI_00010 2.2e-91 yuaB
OLEDPIAI_00011 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
OLEDPIAI_00012 5.4e-237 ktrB P Potassium
OLEDPIAI_00013 1e-38 yiaA S yiaA/B two helix domain
OLEDPIAI_00014 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OLEDPIAI_00015 6.2e-277 yubD P Major Facilitator Superfamily
OLEDPIAI_00016 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
OLEDPIAI_00018 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OLEDPIAI_00019 6.3e-197 yubA S transporter activity
OLEDPIAI_00020 3.3e-183 ygjR S Oxidoreductase
OLEDPIAI_00021 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
OLEDPIAI_00022 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
OLEDPIAI_00023 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
OLEDPIAI_00024 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
OLEDPIAI_00025 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
OLEDPIAI_00026 5.1e-239 mcpA NT chemotaxis protein
OLEDPIAI_00027 2.2e-295 mcpA NT chemotaxis protein
OLEDPIAI_00028 1.5e-222 mcpA NT chemotaxis protein
OLEDPIAI_00029 3.2e-225 mcpA NT chemotaxis protein
OLEDPIAI_00030 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
OLEDPIAI_00031 1e-35
OLEDPIAI_00032 2.1e-72 yugU S Uncharacterised protein family UPF0047
OLEDPIAI_00033 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
OLEDPIAI_00034 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
OLEDPIAI_00035 1.4e-116 yugP S Zn-dependent protease
OLEDPIAI_00036 4.6e-39
OLEDPIAI_00037 1.1e-53 mstX S Membrane-integrating protein Mistic
OLEDPIAI_00038 1.7e-182 yugO P COG1226 Kef-type K transport systems
OLEDPIAI_00039 1.3e-72 yugN S YugN-like family
OLEDPIAI_00041 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
OLEDPIAI_00042 2.8e-229 yugK C Dehydrogenase
OLEDPIAI_00043 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
OLEDPIAI_00044 1.1e-34 yuzA S Domain of unknown function (DUF378)
OLEDPIAI_00045 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
OLEDPIAI_00046 4.3e-200 yugH 2.6.1.1 E Aminotransferase
OLEDPIAI_00047 1.6e-85 alaR K Transcriptional regulator
OLEDPIAI_00048 1e-156 yugF I Hydrolase
OLEDPIAI_00049 9.8e-42 yugE S Domain of unknown function (DUF1871)
OLEDPIAI_00050 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OLEDPIAI_00051 4.6e-233 T PhoQ Sensor
OLEDPIAI_00052 2e-70 kapB G Kinase associated protein B
OLEDPIAI_00053 1.9e-115 kapD L the KinA pathway to sporulation
OLEDPIAI_00055 3.5e-186 yuxJ EGP Major facilitator Superfamily
OLEDPIAI_00056 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
OLEDPIAI_00057 6.3e-75 yuxK S protein conserved in bacteria
OLEDPIAI_00058 6.3e-78 yufK S Family of unknown function (DUF5366)
OLEDPIAI_00059 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OLEDPIAI_00060 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
OLEDPIAI_00061 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OLEDPIAI_00062 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OLEDPIAI_00063 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
OLEDPIAI_00064 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
OLEDPIAI_00065 1.3e-233 maeN C COG3493 Na citrate symporter
OLEDPIAI_00066 1.9e-14
OLEDPIAI_00067 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OLEDPIAI_00068 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OLEDPIAI_00069 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OLEDPIAI_00070 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OLEDPIAI_00071 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OLEDPIAI_00072 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OLEDPIAI_00073 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
OLEDPIAI_00074 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
OLEDPIAI_00075 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLEDPIAI_00076 0.0 comP 2.7.13.3 T Histidine kinase
OLEDPIAI_00078 2.5e-162 comQ H Polyprenyl synthetase
OLEDPIAI_00080 1.1e-22 yuzC
OLEDPIAI_00081 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
OLEDPIAI_00082 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OLEDPIAI_00083 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
OLEDPIAI_00084 1.6e-67 yueI S Protein of unknown function (DUF1694)
OLEDPIAI_00085 9.7e-39 yueH S YueH-like protein
OLEDPIAI_00086 2.1e-32 yueG S Spore germination protein gerPA/gerPF
OLEDPIAI_00087 1.9e-190 yueF S transporter activity
OLEDPIAI_00088 6.1e-72 S Protein of unknown function (DUF2283)
OLEDPIAI_00089 2.9e-24 S Protein of unknown function (DUF2642)
OLEDPIAI_00090 4.8e-96 yueE S phosphohydrolase
OLEDPIAI_00091 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLEDPIAI_00092 6.6e-65 yueC S Family of unknown function (DUF5383)
OLEDPIAI_00093 0.0 esaA S type VII secretion protein EsaA
OLEDPIAI_00094 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OLEDPIAI_00095 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
OLEDPIAI_00096 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
OLEDPIAI_00097 2.8e-45 esxA S Belongs to the WXG100 family
OLEDPIAI_00098 6.5e-229 yukF QT Transcriptional regulator
OLEDPIAI_00099 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
OLEDPIAI_00100 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
OLEDPIAI_00101 3.8e-36 mbtH S MbtH-like protein
OLEDPIAI_00102 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLEDPIAI_00103 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
OLEDPIAI_00104 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
OLEDPIAI_00105 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
OLEDPIAI_00106 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_00107 1.3e-167 besA S Putative esterase
OLEDPIAI_00108 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
OLEDPIAI_00109 1.1e-93 bioY S Biotin biosynthesis protein
OLEDPIAI_00110 3.9e-211 yuiF S antiporter
OLEDPIAI_00111 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OLEDPIAI_00112 1.2e-77 yuiD S protein conserved in bacteria
OLEDPIAI_00113 5.6e-118 yuiC S protein conserved in bacteria
OLEDPIAI_00114 8.4e-27 yuiB S Putative membrane protein
OLEDPIAI_00115 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
OLEDPIAI_00116 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
OLEDPIAI_00118 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OLEDPIAI_00119 9e-118 paiB K Putative FMN-binding domain
OLEDPIAI_00120 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLEDPIAI_00121 3.7e-63 erpA S Belongs to the HesB IscA family
OLEDPIAI_00122 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OLEDPIAI_00123 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OLEDPIAI_00124 3.2e-39 yuzB S Belongs to the UPF0349 family
OLEDPIAI_00125 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
OLEDPIAI_00126 3.5e-57 yuzD S protein conserved in bacteria
OLEDPIAI_00127 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
OLEDPIAI_00128 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
OLEDPIAI_00129 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OLEDPIAI_00130 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OLEDPIAI_00131 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
OLEDPIAI_00132 2e-199 yutH S Spore coat protein
OLEDPIAI_00133 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OLEDPIAI_00134 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OLEDPIAI_00135 1e-75 yutE S Protein of unknown function DUF86
OLEDPIAI_00136 9.7e-48 yutD S protein conserved in bacteria
OLEDPIAI_00137 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OLEDPIAI_00138 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OLEDPIAI_00139 4.5e-196 lytH M Peptidase, M23
OLEDPIAI_00140 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
OLEDPIAI_00141 4.8e-48 yunC S Domain of unknown function (DUF1805)
OLEDPIAI_00142 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OLEDPIAI_00143 2e-141 yunE S membrane transporter protein
OLEDPIAI_00144 4.3e-171 yunF S Protein of unknown function DUF72
OLEDPIAI_00145 3e-62 yunG
OLEDPIAI_00146 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
OLEDPIAI_00147 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
OLEDPIAI_00148 2.1e-236 pbuX F Permease family
OLEDPIAI_00149 1.3e-224 pbuX F xanthine
OLEDPIAI_00150 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
OLEDPIAI_00151 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
OLEDPIAI_00152 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
OLEDPIAI_00153 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
OLEDPIAI_00154 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
OLEDPIAI_00155 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
OLEDPIAI_00156 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OLEDPIAI_00158 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OLEDPIAI_00159 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OLEDPIAI_00160 2e-168 bsn L Ribonuclease
OLEDPIAI_00161 1.2e-205 msmX P Belongs to the ABC transporter superfamily
OLEDPIAI_00162 1.1e-135 yurK K UTRA
OLEDPIAI_00163 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
OLEDPIAI_00164 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
OLEDPIAI_00165 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
OLEDPIAI_00166 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
OLEDPIAI_00167 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
OLEDPIAI_00168 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
OLEDPIAI_00169 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
OLEDPIAI_00171 1e-41
OLEDPIAI_00172 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLEDPIAI_00173 3.5e-271 sufB O FeS cluster assembly
OLEDPIAI_00174 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
OLEDPIAI_00175 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OLEDPIAI_00176 1.4e-245 sufD O assembly protein SufD
OLEDPIAI_00177 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OLEDPIAI_00178 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OLEDPIAI_00179 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
OLEDPIAI_00180 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
OLEDPIAI_00181 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OLEDPIAI_00182 2.4e-56 yusD S SCP-2 sterol transfer family
OLEDPIAI_00183 5.6e-55 traF CO Thioredoxin
OLEDPIAI_00184 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
OLEDPIAI_00185 1.1e-39 yusG S Protein of unknown function (DUF2553)
OLEDPIAI_00186 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OLEDPIAI_00187 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
OLEDPIAI_00188 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
OLEDPIAI_00189 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
OLEDPIAI_00190 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
OLEDPIAI_00191 4.7e-09 S YuzL-like protein
OLEDPIAI_00192 2.2e-165 fadM E Proline dehydrogenase
OLEDPIAI_00193 5.1e-40
OLEDPIAI_00194 3.2e-53 yusN M Coat F domain
OLEDPIAI_00195 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
OLEDPIAI_00196 3.8e-293 yusP P Major facilitator superfamily
OLEDPIAI_00197 8.4e-66 yusQ S Tautomerase enzyme
OLEDPIAI_00198 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_00199 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_00200 2.7e-160 yusT K LysR substrate binding domain
OLEDPIAI_00201 3.8e-47 yusU S Protein of unknown function (DUF2573)
OLEDPIAI_00202 1e-153 yusV 3.6.3.34 HP ABC transporter
OLEDPIAI_00203 5.6e-66 S YusW-like protein
OLEDPIAI_00204 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
OLEDPIAI_00205 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
OLEDPIAI_00206 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_00207 1.2e-79 dps P Ferritin-like domain
OLEDPIAI_00208 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OLEDPIAI_00209 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_00210 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
OLEDPIAI_00211 4.3e-158 yuxN K Transcriptional regulator
OLEDPIAI_00212 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OLEDPIAI_00213 2.3e-24 S Protein of unknown function (DUF3970)
OLEDPIAI_00214 3.7e-247 gerAA EG Spore germination protein
OLEDPIAI_00215 4.5e-197 gerAB E Spore germination protein
OLEDPIAI_00216 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
OLEDPIAI_00217 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLEDPIAI_00218 5.5e-187 vraS 2.7.13.3 T Histidine kinase
OLEDPIAI_00219 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
OLEDPIAI_00220 9.3e-129 liaG S Putative adhesin
OLEDPIAI_00221 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
OLEDPIAI_00222 5.6e-62 liaI S membrane
OLEDPIAI_00223 4.8e-227 yvqJ EGP Major facilitator Superfamily
OLEDPIAI_00224 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
OLEDPIAI_00225 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
OLEDPIAI_00226 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_00227 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
OLEDPIAI_00228 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_00229 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
OLEDPIAI_00230 0.0 T PhoQ Sensor
OLEDPIAI_00231 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_00232 3.6e-22
OLEDPIAI_00233 1.8e-96 yvrI K RNA polymerase
OLEDPIAI_00234 2.4e-19 S YvrJ protein family
OLEDPIAI_00235 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
OLEDPIAI_00236 1.3e-64 yvrL S Regulatory protein YrvL
OLEDPIAI_00237 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
OLEDPIAI_00238 7.1e-124 macB V ABC transporter, ATP-binding protein
OLEDPIAI_00239 4.8e-176 M Efflux transporter rnd family, mfp subunit
OLEDPIAI_00240 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
OLEDPIAI_00241 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_00242 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_00243 2.1e-179 fhuD P ABC transporter
OLEDPIAI_00245 2.6e-237 yvsH E Arginine ornithine antiporter
OLEDPIAI_00246 6.5e-16 S Small spore protein J (Spore_SspJ)
OLEDPIAI_00247 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
OLEDPIAI_00248 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OLEDPIAI_00249 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
OLEDPIAI_00250 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
OLEDPIAI_00251 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
OLEDPIAI_00252 9.1e-158 yvgN S reductase
OLEDPIAI_00253 5.4e-86 yvgO
OLEDPIAI_00254 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
OLEDPIAI_00255 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OLEDPIAI_00256 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OLEDPIAI_00257 0.0 helD 3.6.4.12 L DNA helicase
OLEDPIAI_00258 4.1e-107 yvgT S membrane
OLEDPIAI_00259 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
OLEDPIAI_00260 1.6e-104 bdbD O Thioredoxin
OLEDPIAI_00261 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OLEDPIAI_00262 0.0 copA 3.6.3.54 P P-type ATPase
OLEDPIAI_00263 1.5e-29 copZ P Copper resistance protein CopZ
OLEDPIAI_00264 2.2e-48 csoR S transcriptional
OLEDPIAI_00265 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
OLEDPIAI_00266 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OLEDPIAI_00267 0.0 yvaC S Fusaric acid resistance protein-like
OLEDPIAI_00268 5.7e-73 yvaD S Family of unknown function (DUF5360)
OLEDPIAI_00269 2.8e-55 yvaE P Small Multidrug Resistance protein
OLEDPIAI_00270 4.1e-101 K Bacterial regulatory proteins, tetR family
OLEDPIAI_00271 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_00273 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OLEDPIAI_00274 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OLEDPIAI_00275 5.6e-143 est 3.1.1.1 S Carboxylesterase
OLEDPIAI_00276 2.4e-23 secG U Preprotein translocase subunit SecG
OLEDPIAI_00277 3.7e-153 yvaM S Serine aminopeptidase, S33
OLEDPIAI_00278 7.5e-36 yvzC K Transcriptional
OLEDPIAI_00279 4e-69 K transcriptional
OLEDPIAI_00280 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
OLEDPIAI_00281 2.2e-54 yodB K transcriptional
OLEDPIAI_00282 4.2e-226 NT chemotaxis protein
OLEDPIAI_00283 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OLEDPIAI_00284 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OLEDPIAI_00285 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OLEDPIAI_00286 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OLEDPIAI_00287 8.7e-61 yvbF K Belongs to the GbsR family
OLEDPIAI_00288 7.9e-13 S Sporulation delaying protein SdpA
OLEDPIAI_00289 7.6e-172
OLEDPIAI_00290 4.4e-08
OLEDPIAI_00291 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
OLEDPIAI_00292 4.5e-45 sdpR K transcriptional
OLEDPIAI_00293 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OLEDPIAI_00294 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OLEDPIAI_00295 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OLEDPIAI_00296 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OLEDPIAI_00297 1.4e-98 yvbF K Belongs to the GbsR family
OLEDPIAI_00298 6.4e-103 yvbG U UPF0056 membrane protein
OLEDPIAI_00299 8.6e-113 yvbH S YvbH-like oligomerisation region
OLEDPIAI_00300 4.2e-124 exoY M Membrane
OLEDPIAI_00301 0.0 tcaA S response to antibiotic
OLEDPIAI_00302 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
OLEDPIAI_00303 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OLEDPIAI_00304 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
OLEDPIAI_00305 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OLEDPIAI_00306 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OLEDPIAI_00307 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OLEDPIAI_00308 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OLEDPIAI_00309 1.6e-252 araE EGP Major facilitator Superfamily
OLEDPIAI_00310 5.5e-203 araR K transcriptional
OLEDPIAI_00311 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLEDPIAI_00312 3.9e-159 yvbU K Transcriptional regulator
OLEDPIAI_00313 8.5e-157 yvbV EG EamA-like transporter family
OLEDPIAI_00314 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
OLEDPIAI_00315 4.3e-197 yvbX S Glycosyl hydrolase
OLEDPIAI_00316 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OLEDPIAI_00317 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OLEDPIAI_00318 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OLEDPIAI_00319 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLEDPIAI_00320 8.9e-201 desK 2.7.13.3 T Histidine kinase
OLEDPIAI_00321 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
OLEDPIAI_00322 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
OLEDPIAI_00323 2.6e-157 rsbQ S Alpha/beta hydrolase family
OLEDPIAI_00324 1.4e-199 rsbU 3.1.3.3 T response regulator
OLEDPIAI_00325 2.6e-252 galA 3.2.1.89 G arabinogalactan
OLEDPIAI_00326 0.0 lacA 3.2.1.23 G beta-galactosidase
OLEDPIAI_00327 3.2e-150 ganQ P transport
OLEDPIAI_00328 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
OLEDPIAI_00329 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
OLEDPIAI_00330 1.8e-184 lacR K Transcriptional regulator
OLEDPIAI_00331 1e-112 yvfI K COG2186 Transcriptional regulators
OLEDPIAI_00332 1.4e-309 yvfH C L-lactate permease
OLEDPIAI_00333 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OLEDPIAI_00334 1e-31 yvfG S YvfG protein
OLEDPIAI_00335 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
OLEDPIAI_00336 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OLEDPIAI_00337 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
OLEDPIAI_00338 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OLEDPIAI_00339 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLEDPIAI_00340 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
OLEDPIAI_00341 3.6e-207 epsI GM pyruvyl transferase
OLEDPIAI_00342 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
OLEDPIAI_00343 4.8e-207 epsG S EpsG family
OLEDPIAI_00344 5.3e-220 epsF GT4 M Glycosyl transferases group 1
OLEDPIAI_00345 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OLEDPIAI_00346 2e-224 epsD GT4 M Glycosyl transferase 4-like
OLEDPIAI_00347 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
OLEDPIAI_00348 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
OLEDPIAI_00349 4e-122 ywqC M biosynthesis protein
OLEDPIAI_00350 5.7e-77 slr K transcriptional
OLEDPIAI_00351 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OLEDPIAI_00353 4.6e-93 padC Q Phenolic acid decarboxylase
OLEDPIAI_00354 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
OLEDPIAI_00355 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OLEDPIAI_00356 9.6e-266 pbpE V Beta-lactamase
OLEDPIAI_00357 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
OLEDPIAI_00358 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
OLEDPIAI_00359 1.8e-295 yveA E amino acid
OLEDPIAI_00360 2.6e-106 yvdT K Transcriptional regulator
OLEDPIAI_00361 6.7e-51 ykkC P Small Multidrug Resistance protein
OLEDPIAI_00362 4.1e-50 sugE P Small Multidrug Resistance protein
OLEDPIAI_00363 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
OLEDPIAI_00364 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
OLEDPIAI_00365 1.5e-183 S Patatin-like phospholipase
OLEDPIAI_00367 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OLEDPIAI_00368 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
OLEDPIAI_00369 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
OLEDPIAI_00370 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
OLEDPIAI_00371 1.2e-158 malA S Protein of unknown function (DUF1189)
OLEDPIAI_00372 7.8e-149 malD P transport
OLEDPIAI_00373 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
OLEDPIAI_00374 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
OLEDPIAI_00375 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
OLEDPIAI_00376 3.6e-174 yvdE K Transcriptional regulator
OLEDPIAI_00377 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
OLEDPIAI_00378 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
OLEDPIAI_00379 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
OLEDPIAI_00380 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OLEDPIAI_00381 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OLEDPIAI_00382 0.0 yxdM V ABC transporter (permease)
OLEDPIAI_00383 5.6e-141 yvcR V ABC transporter, ATP-binding protein
OLEDPIAI_00384 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
OLEDPIAI_00385 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_00386 1.8e-33
OLEDPIAI_00387 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
OLEDPIAI_00388 1.6e-36 crh G Phosphocarrier protein Chr
OLEDPIAI_00389 1.4e-170 whiA K May be required for sporulation
OLEDPIAI_00390 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OLEDPIAI_00391 5.7e-166 rapZ S Displays ATPase and GTPase activities
OLEDPIAI_00392 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OLEDPIAI_00393 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OLEDPIAI_00394 1.6e-101 usp CBM50 M protein conserved in bacteria
OLEDPIAI_00395 2.4e-278 S COG0457 FOG TPR repeat
OLEDPIAI_00396 0.0 msbA2 3.6.3.44 V ABC transporter
OLEDPIAI_00398 0.0
OLEDPIAI_00399 4.6e-121
OLEDPIAI_00400 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
OLEDPIAI_00401 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OLEDPIAI_00402 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OLEDPIAI_00403 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OLEDPIAI_00404 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OLEDPIAI_00405 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OLEDPIAI_00406 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OLEDPIAI_00407 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OLEDPIAI_00408 4.5e-140 yvpB NU protein conserved in bacteria
OLEDPIAI_00409 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
OLEDPIAI_00410 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
OLEDPIAI_00411 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OLEDPIAI_00412 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
OLEDPIAI_00413 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OLEDPIAI_00414 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OLEDPIAI_00415 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OLEDPIAI_00416 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OLEDPIAI_00417 3.6e-134 yvoA K transcriptional
OLEDPIAI_00418 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
OLEDPIAI_00419 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
OLEDPIAI_00420 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
OLEDPIAI_00421 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
OLEDPIAI_00422 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
OLEDPIAI_00423 2.7e-203 yvmA EGP Major facilitator Superfamily
OLEDPIAI_00424 1.2e-50 yvlD S Membrane
OLEDPIAI_00425 2.6e-26 pspB KT PspC domain
OLEDPIAI_00426 3.4e-168 yvlB S Putative adhesin
OLEDPIAI_00427 8e-49 yvlA
OLEDPIAI_00428 6.7e-34 yvkN
OLEDPIAI_00429 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OLEDPIAI_00430 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OLEDPIAI_00431 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OLEDPIAI_00432 1.2e-30 csbA S protein conserved in bacteria
OLEDPIAI_00433 0.0 yvkC 2.7.9.2 GT Phosphotransferase
OLEDPIAI_00434 7e-101 yvkB K Transcriptional regulator
OLEDPIAI_00435 7.9e-228 yvkA EGP Major facilitator Superfamily
OLEDPIAI_00436 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OLEDPIAI_00437 5.3e-56 swrA S Swarming motility protein
OLEDPIAI_00438 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
OLEDPIAI_00439 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OLEDPIAI_00440 1.6e-123 ftsE D cell division ATP-binding protein FtsE
OLEDPIAI_00441 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
OLEDPIAI_00442 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
OLEDPIAI_00443 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OLEDPIAI_00444 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OLEDPIAI_00445 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OLEDPIAI_00446 2.8e-66
OLEDPIAI_00447 1.9e-08 fliT S bacterial-type flagellum organization
OLEDPIAI_00448 2.9e-69 fliS N flagellar protein FliS
OLEDPIAI_00449 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OLEDPIAI_00450 6.1e-57 flaG N flagellar protein FlaG
OLEDPIAI_00451 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OLEDPIAI_00452 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OLEDPIAI_00453 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OLEDPIAI_00454 2.6e-50 yviE
OLEDPIAI_00455 1.1e-156 flgL N Belongs to the bacterial flagellin family
OLEDPIAI_00456 2e-264 flgK N flagellar hook-associated protein
OLEDPIAI_00457 2.4e-78 flgN NOU FlgN protein
OLEDPIAI_00458 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
OLEDPIAI_00459 7e-74 yvyF S flagellar protein
OLEDPIAI_00460 2.7e-129 comFC S Phosphoribosyl transferase domain
OLEDPIAI_00461 5.7e-46 comFB S Late competence development protein ComFB
OLEDPIAI_00462 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OLEDPIAI_00463 7.3e-155 degV S protein conserved in bacteria
OLEDPIAI_00464 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLEDPIAI_00465 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OLEDPIAI_00466 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
OLEDPIAI_00467 6e-163 yvhJ K Transcriptional regulator
OLEDPIAI_00468 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OLEDPIAI_00469 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
OLEDPIAI_00470 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
OLEDPIAI_00471 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
OLEDPIAI_00472 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
OLEDPIAI_00473 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OLEDPIAI_00474 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
OLEDPIAI_00475 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLEDPIAI_00476 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OLEDPIAI_00477 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OLEDPIAI_00478 0.0 lytB 3.5.1.28 D Stage II sporulation protein
OLEDPIAI_00479 6e-38
OLEDPIAI_00480 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OLEDPIAI_00481 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OLEDPIAI_00482 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OLEDPIAI_00483 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
OLEDPIAI_00484 8.1e-257 ggaA M Glycosyltransferase like family 2
OLEDPIAI_00486 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OLEDPIAI_00487 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OLEDPIAI_00488 1.1e-150 tagG GM Transport permease protein
OLEDPIAI_00489 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OLEDPIAI_00490 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
OLEDPIAI_00491 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OLEDPIAI_00492 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OLEDPIAI_00493 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OLEDPIAI_00494 1.2e-260
OLEDPIAI_00495 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OLEDPIAI_00496 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
OLEDPIAI_00497 3.5e-266 gerBA EG Spore germination protein
OLEDPIAI_00498 7.5e-200 gerBB E Spore germination protein
OLEDPIAI_00499 7.6e-216 gerAC S Spore germination protein
OLEDPIAI_00500 1.9e-248 ywtG EGP Major facilitator Superfamily
OLEDPIAI_00501 8.4e-171 ywtF K Transcriptional regulator
OLEDPIAI_00502 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
OLEDPIAI_00503 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OLEDPIAI_00504 3.6e-21 ywtC
OLEDPIAI_00505 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
OLEDPIAI_00506 8.6e-70 pgsC S biosynthesis protein
OLEDPIAI_00507 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
OLEDPIAI_00508 1.9e-178 rbsR K transcriptional
OLEDPIAI_00509 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OLEDPIAI_00510 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OLEDPIAI_00511 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OLEDPIAI_00512 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
OLEDPIAI_00513 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
OLEDPIAI_00514 4.6e-94 batE T Sh3 type 3 domain protein
OLEDPIAI_00515 3.6e-48 ywsA S Protein of unknown function (DUF3892)
OLEDPIAI_00516 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
OLEDPIAI_00517 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
OLEDPIAI_00518 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OLEDPIAI_00519 1.1e-169 alsR K LysR substrate binding domain
OLEDPIAI_00520 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OLEDPIAI_00521 7.5e-126 ywrJ
OLEDPIAI_00522 7.6e-131 cotB
OLEDPIAI_00523 1.2e-210 cotH M Spore Coat
OLEDPIAI_00524 3.7e-12
OLEDPIAI_00525 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OLEDPIAI_00526 2.9e-54 S Domain of unknown function (DUF4181)
OLEDPIAI_00527 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OLEDPIAI_00528 2.1e-82 ywrC K Transcriptional regulator
OLEDPIAI_00529 2.4e-104 ywrB P Chromate transporter
OLEDPIAI_00530 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
OLEDPIAI_00532 2.7e-102 ywqN S NAD(P)H-dependent
OLEDPIAI_00533 2.9e-162 K Transcriptional regulator
OLEDPIAI_00534 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
OLEDPIAI_00535 1.7e-52 S MORN repeat variant
OLEDPIAI_00536 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
OLEDPIAI_00537 1.3e-38 ywqI S Family of unknown function (DUF5344)
OLEDPIAI_00538 3.3e-15 S Domain of unknown function (DUF5082)
OLEDPIAI_00539 3.4e-154 ywqG S Domain of unknown function (DUF1963)
OLEDPIAI_00540 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OLEDPIAI_00541 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
OLEDPIAI_00542 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
OLEDPIAI_00543 2e-116 ywqC M biosynthesis protein
OLEDPIAI_00544 1.2e-17
OLEDPIAI_00545 3.8e-309 ywqB S SWIM zinc finger
OLEDPIAI_00546 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OLEDPIAI_00547 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
OLEDPIAI_00548 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
OLEDPIAI_00549 9.8e-58 ssbB L Single-stranded DNA-binding protein
OLEDPIAI_00550 1.3e-66 ywpG
OLEDPIAI_00551 1.1e-66 ywpF S YwpF-like protein
OLEDPIAI_00552 8e-51 srtA 3.4.22.70 M Sortase family
OLEDPIAI_00553 1.9e-153 ywpD T Histidine kinase
OLEDPIAI_00554 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OLEDPIAI_00555 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OLEDPIAI_00556 2.1e-199 S aspartate phosphatase
OLEDPIAI_00557 1.5e-141 flhP N flagellar basal body
OLEDPIAI_00558 6.9e-126 flhO N flagellar basal body
OLEDPIAI_00559 3.5e-180 mbl D Rod shape-determining protein
OLEDPIAI_00560 3e-44 spoIIID K Stage III sporulation protein D
OLEDPIAI_00561 2.1e-70 ywoH K COG1846 Transcriptional regulators
OLEDPIAI_00562 2.7e-211 ywoG EGP Major facilitator Superfamily
OLEDPIAI_00563 1.2e-231 ywoF P Right handed beta helix region
OLEDPIAI_00564 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
OLEDPIAI_00565 4.4e-242 ywoD EGP Major facilitator superfamily
OLEDPIAI_00566 4e-104 phzA Q Isochorismatase family
OLEDPIAI_00567 1.2e-77
OLEDPIAI_00568 2.5e-225 amt P Ammonium transporter
OLEDPIAI_00569 1.6e-58 nrgB K Belongs to the P(II) protein family
OLEDPIAI_00570 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OLEDPIAI_00571 3.5e-73 ywnJ S VanZ like family
OLEDPIAI_00572 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
OLEDPIAI_00573 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
OLEDPIAI_00574 2.7e-14 ywnC S Family of unknown function (DUF5362)
OLEDPIAI_00575 2.2e-70 ywnF S Family of unknown function (DUF5392)
OLEDPIAI_00576 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OLEDPIAI_00577 4.1e-144 mta K transcriptional
OLEDPIAI_00578 2.6e-59 ywnC S Family of unknown function (DUF5362)
OLEDPIAI_00579 1.6e-114 ywnB S NAD(P)H-binding
OLEDPIAI_00580 1.7e-64 ywnA K Transcriptional regulator
OLEDPIAI_00581 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OLEDPIAI_00582 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OLEDPIAI_00583 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OLEDPIAI_00585 3.8e-11 csbD K CsbD-like
OLEDPIAI_00586 3e-84 ywmF S Peptidase M50
OLEDPIAI_00587 1.3e-103 S response regulator aspartate phosphatase
OLEDPIAI_00588 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OLEDPIAI_00589 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OLEDPIAI_00591 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
OLEDPIAI_00592 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
OLEDPIAI_00593 2e-178 spoIID D Stage II sporulation protein D
OLEDPIAI_00594 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OLEDPIAI_00595 1.6e-134 ywmB S TATA-box binding
OLEDPIAI_00596 1.3e-32 ywzB S membrane
OLEDPIAI_00597 4.3e-88 ywmA
OLEDPIAI_00598 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OLEDPIAI_00599 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OLEDPIAI_00600 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OLEDPIAI_00601 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OLEDPIAI_00602 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OLEDPIAI_00603 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OLEDPIAI_00604 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OLEDPIAI_00605 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
OLEDPIAI_00606 2.5e-62 atpI S ATP synthase
OLEDPIAI_00607 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OLEDPIAI_00608 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OLEDPIAI_00609 7.2e-95 ywlG S Belongs to the UPF0340 family
OLEDPIAI_00610 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
OLEDPIAI_00611 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OLEDPIAI_00612 1.7e-91 mntP P Probably functions as a manganese efflux pump
OLEDPIAI_00613 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OLEDPIAI_00614 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
OLEDPIAI_00615 6.1e-112 spoIIR S stage II sporulation protein R
OLEDPIAI_00616 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
OLEDPIAI_00618 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OLEDPIAI_00619 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OLEDPIAI_00620 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLEDPIAI_00621 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
OLEDPIAI_00622 8.6e-160 ywkB S Membrane transport protein
OLEDPIAI_00623 0.0 sfcA 1.1.1.38 C malic enzyme
OLEDPIAI_00624 2.4e-104 tdk 2.7.1.21 F thymidine kinase
OLEDPIAI_00625 1.1e-32 rpmE J Binds the 23S rRNA
OLEDPIAI_00626 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OLEDPIAI_00627 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
OLEDPIAI_00628 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OLEDPIAI_00629 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OLEDPIAI_00630 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
OLEDPIAI_00631 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
OLEDPIAI_00632 2.4e-92 ywjG S Domain of unknown function (DUF2529)
OLEDPIAI_00633 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OLEDPIAI_00634 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OLEDPIAI_00635 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
OLEDPIAI_00636 0.0 fadF C COG0247 Fe-S oxidoreductase
OLEDPIAI_00637 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OLEDPIAI_00638 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
OLEDPIAI_00639 2.7e-42 ywjC
OLEDPIAI_00640 4.8e-96 ywjB H RibD C-terminal domain
OLEDPIAI_00641 0.0 ywjA V ABC transporter
OLEDPIAI_00642 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OLEDPIAI_00643 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
OLEDPIAI_00644 2.4e-98 narJ 1.7.5.1 C nitrate reductase
OLEDPIAI_00645 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
OLEDPIAI_00646 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OLEDPIAI_00647 7e-86 arfM T cyclic nucleotide binding
OLEDPIAI_00648 4.3e-140 ywiC S YwiC-like protein
OLEDPIAI_00649 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
OLEDPIAI_00650 9.8e-214 narK P COG2223 Nitrate nitrite transporter
OLEDPIAI_00651 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OLEDPIAI_00652 4.7e-73 ywiB S protein conserved in bacteria
OLEDPIAI_00653 1e-07 S Bacteriocin subtilosin A
OLEDPIAI_00654 2.6e-271 C Fe-S oxidoreductases
OLEDPIAI_00656 3.3e-132 cbiO V ABC transporter
OLEDPIAI_00657 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
OLEDPIAI_00658 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
OLEDPIAI_00659 1.2e-249 L Peptidase, M16
OLEDPIAI_00661 2.9e-249 ywhL CO amine dehydrogenase activity
OLEDPIAI_00662 2.5e-205 ywhK CO amine dehydrogenase activity
OLEDPIAI_00663 2.3e-79 S aspartate phosphatase
OLEDPIAI_00665 1e-84 ywhH S Aminoacyl-tRNA editing domain
OLEDPIAI_00666 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
OLEDPIAI_00667 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OLEDPIAI_00668 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OLEDPIAI_00669 5.2e-95 ywhD S YwhD family
OLEDPIAI_00670 5.1e-119 ywhC S Peptidase family M50
OLEDPIAI_00671 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
OLEDPIAI_00672 3.3e-71 ywhA K Transcriptional regulator
OLEDPIAI_00673 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OLEDPIAI_00675 2.6e-242 mmr U Major Facilitator Superfamily
OLEDPIAI_00676 2.8e-79 yffB K Transcriptional regulator
OLEDPIAI_00677 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
OLEDPIAI_00678 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
OLEDPIAI_00679 3.1e-36 ywzC S Belongs to the UPF0741 family
OLEDPIAI_00680 1.6e-111 rsfA_1
OLEDPIAI_00681 5.2e-159 ywfM EG EamA-like transporter family
OLEDPIAI_00682 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OLEDPIAI_00683 9.2e-164 cysL K Transcriptional regulator
OLEDPIAI_00684 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
OLEDPIAI_00685 1.1e-146 ywfI C May function as heme-dependent peroxidase
OLEDPIAI_00686 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
OLEDPIAI_00687 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
OLEDPIAI_00688 2.9e-210 bacE EGP Major facilitator Superfamily
OLEDPIAI_00689 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
OLEDPIAI_00690 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLEDPIAI_00691 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
OLEDPIAI_00692 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
OLEDPIAI_00693 4.6e-206 ywfA EGP Major facilitator Superfamily
OLEDPIAI_00694 4e-262 lysP E amino acid
OLEDPIAI_00695 0.0 rocB E arginine degradation protein
OLEDPIAI_00696 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OLEDPIAI_00697 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OLEDPIAI_00698 1.8e-78
OLEDPIAI_00699 3.5e-87 spsL 5.1.3.13 M Spore Coat
OLEDPIAI_00700 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OLEDPIAI_00701 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OLEDPIAI_00702 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OLEDPIAI_00703 1.7e-190 spsG M Spore Coat
OLEDPIAI_00704 9.7e-132 spsF M Spore Coat
OLEDPIAI_00705 3.2e-214 spsE 2.5.1.56 M acid synthase
OLEDPIAI_00706 4e-164 spsD 2.3.1.210 K Spore Coat
OLEDPIAI_00707 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
OLEDPIAI_00708 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
OLEDPIAI_00709 2.8e-145 spsA M Spore Coat
OLEDPIAI_00710 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OLEDPIAI_00711 4.3e-59 ywdK S small membrane protein
OLEDPIAI_00712 1.3e-238 ywdJ F Xanthine uracil
OLEDPIAI_00713 7.7e-49 ywdI S Family of unknown function (DUF5327)
OLEDPIAI_00714 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OLEDPIAI_00715 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OLEDPIAI_00716 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
OLEDPIAI_00718 1.4e-113 ywdD
OLEDPIAI_00719 1.3e-57 pex K Transcriptional regulator PadR-like family
OLEDPIAI_00720 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OLEDPIAI_00721 2e-28 ywdA
OLEDPIAI_00722 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
OLEDPIAI_00723 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLEDPIAI_00724 1e-139 focA P Formate/nitrite transporter
OLEDPIAI_00725 2.4e-150 sacT K transcriptional antiterminator
OLEDPIAI_00727 0.0 vpr O Belongs to the peptidase S8 family
OLEDPIAI_00728 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLEDPIAI_00729 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
OLEDPIAI_00730 2.9e-202 rodA D Belongs to the SEDS family
OLEDPIAI_00731 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
OLEDPIAI_00732 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OLEDPIAI_00733 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OLEDPIAI_00734 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OLEDPIAI_00735 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OLEDPIAI_00736 1e-35 ywzA S membrane
OLEDPIAI_00737 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OLEDPIAI_00738 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OLEDPIAI_00739 9.5e-60 gtcA S GtrA-like protein
OLEDPIAI_00740 2.2e-122 ywcC K transcriptional regulator
OLEDPIAI_00742 9.8e-49 ywcB S Protein of unknown function, DUF485
OLEDPIAI_00743 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OLEDPIAI_00744 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OLEDPIAI_00745 2.6e-225 ywbN P Dyp-type peroxidase family protein
OLEDPIAI_00746 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
OLEDPIAI_00747 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
OLEDPIAI_00748 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OLEDPIAI_00749 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OLEDPIAI_00750 4.3e-153 ywbI K Transcriptional regulator
OLEDPIAI_00751 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OLEDPIAI_00752 2.3e-111 ywbG M effector of murein hydrolase
OLEDPIAI_00753 1.9e-209 ywbF EGP Major facilitator Superfamily
OLEDPIAI_00754 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
OLEDPIAI_00755 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
OLEDPIAI_00756 4.4e-67 ywbC 4.4.1.5 E glyoxalase
OLEDPIAI_00757 1.8e-127 ywbB S Protein of unknown function (DUF2711)
OLEDPIAI_00758 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OLEDPIAI_00759 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
OLEDPIAI_00760 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLEDPIAI_00761 4e-153 sacY K transcriptional antiterminator
OLEDPIAI_00762 7e-169 gspA M General stress
OLEDPIAI_00763 1.7e-128 ywaF S Integral membrane protein
OLEDPIAI_00764 8.1e-88 ywaE K Transcriptional regulator
OLEDPIAI_00765 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OLEDPIAI_00766 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
OLEDPIAI_00767 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
OLEDPIAI_00768 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
OLEDPIAI_00769 5e-14 S D-Ala-teichoic acid biosynthesis protein
OLEDPIAI_00770 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLEDPIAI_00771 1.2e-232 dltB M membrane protein involved in D-alanine export
OLEDPIAI_00772 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLEDPIAI_00773 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OLEDPIAI_00774 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_00775 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OLEDPIAI_00776 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OLEDPIAI_00777 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
OLEDPIAI_00778 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OLEDPIAI_00779 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
OLEDPIAI_00780 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
OLEDPIAI_00781 1.1e-19 yxzF
OLEDPIAI_00782 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OLEDPIAI_00783 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OLEDPIAI_00784 2.1e-216 yxlH EGP Major facilitator Superfamily
OLEDPIAI_00785 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OLEDPIAI_00786 5.1e-167 yxlF V ABC transporter, ATP-binding protein
OLEDPIAI_00787 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
OLEDPIAI_00788 1.2e-31
OLEDPIAI_00789 3.9e-48 yxlC S Family of unknown function (DUF5345)
OLEDPIAI_00790 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
OLEDPIAI_00791 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
OLEDPIAI_00792 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OLEDPIAI_00793 0.0 cydD V ATP-binding protein
OLEDPIAI_00794 0.0 cydD V ATP-binding
OLEDPIAI_00795 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
OLEDPIAI_00796 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
OLEDPIAI_00797 1.5e-229 cimH C COG3493 Na citrate symporter
OLEDPIAI_00798 0.0 3.4.24.84 O Peptidase family M48
OLEDPIAI_00800 3e-156 yxkH G Polysaccharide deacetylase
OLEDPIAI_00801 5.9e-205 msmK P Belongs to the ABC transporter superfamily
OLEDPIAI_00802 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
OLEDPIAI_00803 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OLEDPIAI_00804 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OLEDPIAI_00805 4.1e-73 yxkC S Domain of unknown function (DUF4352)
OLEDPIAI_00806 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OLEDPIAI_00807 5.1e-95 yxkA S Phosphatidylethanolamine-binding protein
OLEDPIAI_00808 1.9e-166 yxjO K LysR substrate binding domain
OLEDPIAI_00809 2.4e-78 S Protein of unknown function (DUF1453)
OLEDPIAI_00810 1.5e-193 yxjM T Signal transduction histidine kinase
OLEDPIAI_00811 8.9e-116 K helix_turn_helix, Lux Regulon
OLEDPIAI_00812 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OLEDPIAI_00815 1e-87 yxjI S LURP-one-related
OLEDPIAI_00816 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
OLEDPIAI_00817 1e-220 yxjG 2.1.1.14 E Methionine synthase
OLEDPIAI_00818 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OLEDPIAI_00819 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OLEDPIAI_00820 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OLEDPIAI_00821 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
OLEDPIAI_00822 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
OLEDPIAI_00823 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OLEDPIAI_00824 1.2e-22 T Domain of unknown function (DUF4163)
OLEDPIAI_00825 2.7e-48 yxiS
OLEDPIAI_00826 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
OLEDPIAI_00827 6.6e-224 citH C Citrate transporter
OLEDPIAI_00828 5e-144 exoK GH16 M licheninase activity
OLEDPIAI_00829 8.3e-151 licT K transcriptional antiterminator
OLEDPIAI_00830 6.6e-114
OLEDPIAI_00831 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
OLEDPIAI_00832 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
OLEDPIAI_00833 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
OLEDPIAI_00836 1.6e-48 yxiJ S YxiJ-like protein
OLEDPIAI_00837 1.2e-96 yxiI S Protein of unknown function (DUF2716)
OLEDPIAI_00838 3.8e-81
OLEDPIAI_00839 4.9e-46
OLEDPIAI_00840 3.7e-75 yxiG
OLEDPIAI_00841 6.4e-63
OLEDPIAI_00842 1.7e-84
OLEDPIAI_00843 1.5e-71 yxxG
OLEDPIAI_00844 0.0 wapA M COG3209 Rhs family protein
OLEDPIAI_00845 2.9e-168 yxxF EG EamA-like transporter family
OLEDPIAI_00846 1.1e-72 yxiE T Belongs to the universal stress protein A family
OLEDPIAI_00847 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OLEDPIAI_00848 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLEDPIAI_00849 3.6e-51
OLEDPIAI_00850 2.2e-78 S SMI1 / KNR4 family
OLEDPIAI_00851 0.0 S nuclease activity
OLEDPIAI_00852 3.6e-39 yxiC S Family of unknown function (DUF5344)
OLEDPIAI_00853 2.1e-21 S Domain of unknown function (DUF5082)
OLEDPIAI_00854 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OLEDPIAI_00855 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
OLEDPIAI_00856 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
OLEDPIAI_00857 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OLEDPIAI_00858 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
OLEDPIAI_00859 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
OLEDPIAI_00860 6.1e-252 lysP E amino acid
OLEDPIAI_00861 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
OLEDPIAI_00862 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OLEDPIAI_00863 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OLEDPIAI_00864 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OLEDPIAI_00865 3e-153 yxxB S Domain of Unknown Function (DUF1206)
OLEDPIAI_00866 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
OLEDPIAI_00867 2e-255 yxeQ S MmgE/PrpD family
OLEDPIAI_00868 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
OLEDPIAI_00869 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
OLEDPIAI_00870 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
OLEDPIAI_00871 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
OLEDPIAI_00872 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLEDPIAI_00873 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLEDPIAI_00875 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OLEDPIAI_00876 6.2e-151 yidA S hydrolases of the HAD superfamily
OLEDPIAI_00879 1.3e-20 yxeE
OLEDPIAI_00880 1.9e-16 yxeD
OLEDPIAI_00881 8.5e-69
OLEDPIAI_00882 6e-177 fhuD P ABC transporter
OLEDPIAI_00883 1.5e-58 yxeA S Protein of unknown function (DUF1093)
OLEDPIAI_00884 0.0 yxdM V ABC transporter (permease)
OLEDPIAI_00885 9.4e-141 yxdL V ABC transporter, ATP-binding protein
OLEDPIAI_00886 1.3e-182 T PhoQ Sensor
OLEDPIAI_00887 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_00888 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
OLEDPIAI_00889 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
OLEDPIAI_00890 2.3e-167 iolH G Xylose isomerase-like TIM barrel
OLEDPIAI_00891 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
OLEDPIAI_00892 1.3e-235 iolF EGP Major facilitator Superfamily
OLEDPIAI_00893 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
OLEDPIAI_00894 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
OLEDPIAI_00895 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
OLEDPIAI_00896 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
OLEDPIAI_00897 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OLEDPIAI_00898 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
OLEDPIAI_00899 3.7e-176 iolS C Aldo keto reductase
OLEDPIAI_00901 8.3e-48 yxcD S Protein of unknown function (DUF2653)
OLEDPIAI_00902 2.3e-246 csbC EGP Major facilitator Superfamily
OLEDPIAI_00903 0.0 htpG O Molecular chaperone. Has ATPase activity
OLEDPIAI_00905 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
OLEDPIAI_00906 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
OLEDPIAI_00907 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OLEDPIAI_00908 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
OLEDPIAI_00909 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
OLEDPIAI_00910 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OLEDPIAI_00911 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OLEDPIAI_00912 1.8e-37 yaaB S Domain of unknown function (DUF370)
OLEDPIAI_00913 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OLEDPIAI_00914 2.4e-33 yaaA S S4 domain
OLEDPIAI_00915 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OLEDPIAI_00916 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OLEDPIAI_00917 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OLEDPIAI_00918 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OLEDPIAI_00919 6.5e-108 jag S single-stranded nucleic acid binding R3H
OLEDPIAI_00920 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OLEDPIAI_00921 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OLEDPIAI_00922 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OLEDPIAI_00923 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OLEDPIAI_00924 1.5e-74 S Bacterial PH domain
OLEDPIAI_00925 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
OLEDPIAI_00926 2.1e-149 spo0J K Belongs to the ParB family
OLEDPIAI_00927 1.6e-111 yyaC S Sporulation protein YyaC
OLEDPIAI_00928 8.1e-177 yyaD S Membrane
OLEDPIAI_00929 2.3e-33 yyzM S protein conserved in bacteria
OLEDPIAI_00930 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OLEDPIAI_00931 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OLEDPIAI_00932 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
OLEDPIAI_00933 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OLEDPIAI_00934 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OLEDPIAI_00935 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
OLEDPIAI_00936 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
OLEDPIAI_00937 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLEDPIAI_00938 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
OLEDPIAI_00939 3.8e-246 EGP Major facilitator superfamily
OLEDPIAI_00940 9.5e-169 yyaK S CAAX protease self-immunity
OLEDPIAI_00941 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OLEDPIAI_00942 3.3e-161 yyaM EG EamA-like transporter family
OLEDPIAI_00943 5.1e-61 yyaN K MerR HTH family regulatory protein
OLEDPIAI_00944 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
OLEDPIAI_00945 1.7e-249 tetL EGP Major facilitator Superfamily
OLEDPIAI_00946 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
OLEDPIAI_00947 5.4e-67 yyaQ S YjbR
OLEDPIAI_00948 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
OLEDPIAI_00949 1.5e-101 yyaS S Membrane
OLEDPIAI_00950 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
OLEDPIAI_00951 5.6e-77 yybA 2.3.1.57 K transcriptional
OLEDPIAI_00952 3e-127 S Metallo-beta-lactamase superfamily
OLEDPIAI_00953 2.7e-77 yybC
OLEDPIAI_00954 2e-79 yjcF S Acetyltransferase (GNAT) domain
OLEDPIAI_00955 2.1e-165 yybE K Transcriptional regulator
OLEDPIAI_00956 3.2e-220 ynfM EGP Major facilitator Superfamily
OLEDPIAI_00957 3e-124 yybG S Pentapeptide repeat-containing protein
OLEDPIAI_00958 5.9e-67 yybH S SnoaL-like domain
OLEDPIAI_00959 6.2e-132
OLEDPIAI_00960 2.6e-115 V ATPases associated with a variety of cellular activities
OLEDPIAI_00961 2e-127 S Protein of unknown function (DUF2705)
OLEDPIAI_00962 9e-122
OLEDPIAI_00963 4.1e-125
OLEDPIAI_00964 1.3e-78 yybN S Protein of unknown function (DUF2712)
OLEDPIAI_00965 1e-16
OLEDPIAI_00966 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
OLEDPIAI_00968 1.3e-70
OLEDPIAI_00969 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
OLEDPIAI_00970 1.4e-68 ydeP3 K Transcriptional regulator
OLEDPIAI_00971 3.9e-84 cotF M Spore coat protein
OLEDPIAI_00973 2.9e-160 yybS S membrane
OLEDPIAI_00974 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OLEDPIAI_00975 2.2e-73 rplI J binds to the 23S rRNA
OLEDPIAI_00976 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OLEDPIAI_00977 8.4e-221 yeaN P COG2807 Cyanate permease
OLEDPIAI_00978 1.9e-15 yycC K YycC-like protein
OLEDPIAI_00980 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
OLEDPIAI_00981 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OLEDPIAI_00982 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLEDPIAI_00983 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OLEDPIAI_00988 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_00989 0.0 vicK 2.7.13.3 T Histidine kinase
OLEDPIAI_00990 3.6e-260 yycH S protein conserved in bacteria
OLEDPIAI_00991 7.3e-155 yycI S protein conserved in bacteria
OLEDPIAI_00992 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OLEDPIAI_00993 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OLEDPIAI_00994 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OLEDPIAI_00995 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OLEDPIAI_00996 9.7e-261 rocE E amino acid
OLEDPIAI_00997 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OLEDPIAI_00999 5e-188 S aspartate phosphatase
OLEDPIAI_01000 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
OLEDPIAI_01001 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OLEDPIAI_01002 1.6e-221 yycP
OLEDPIAI_01003 2.1e-33 yycQ S Protein of unknown function (DUF2651)
OLEDPIAI_01005 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OLEDPIAI_01006 4.2e-71
OLEDPIAI_01007 1.1e-09 S YyzF-like protein
OLEDPIAI_01008 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OLEDPIAI_01009 7.3e-280 S Calcineurin-like phosphoesterase
OLEDPIAI_01010 3.5e-65
OLEDPIAI_01011 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
OLEDPIAI_01012 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
OLEDPIAI_01013 8e-12
OLEDPIAI_01014 7.7e-185 S Radical SAM superfamily
OLEDPIAI_01015 8.4e-134 yydH O Peptidase M50
OLEDPIAI_01016 1.8e-110 prrC P ABC transporter
OLEDPIAI_01017 3.3e-119 S ABC-2 family transporter protein
OLEDPIAI_01018 7.6e-13
OLEDPIAI_01019 1.3e-128 yydK K Transcriptional regulator
OLEDPIAI_01020 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
OLEDPIAI_01021 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OLEDPIAI_01022 3.8e-287 ahpF O Alkyl hydroperoxide reductase
OLEDPIAI_01023 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
OLEDPIAI_01024 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OLEDPIAI_01025 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
OLEDPIAI_01026 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
OLEDPIAI_01027 7.3e-127 gntR K transcriptional
OLEDPIAI_01028 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OLEDPIAI_01029 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
OLEDPIAI_01030 2.6e-118 yxaC M effector of murein hydrolase
OLEDPIAI_01031 5.2e-50 S LrgA family
OLEDPIAI_01032 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
OLEDPIAI_01033 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_01034 7.1e-101 yxaF K Transcriptional regulator
OLEDPIAI_01035 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
OLEDPIAI_01036 1.4e-228 P Protein of unknown function (DUF418)
OLEDPIAI_01037 1.1e-75 yxaI S membrane protein domain
OLEDPIAI_01038 3.5e-65 S Family of unknown function (DUF5391)
OLEDPIAI_01039 6.8e-93 S PQQ-like domain
OLEDPIAI_01040 7.6e-214 yxaM U MFS_1 like family
OLEDPIAI_01041 0.0 asnB 6.3.5.4 E Asparagine synthase
OLEDPIAI_01042 1.1e-86 yxnB
OLEDPIAI_01043 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
OLEDPIAI_01044 3.3e-127 yxbB Q Met-10+ like-protein
OLEDPIAI_01045 7.8e-08
OLEDPIAI_01047 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OLEDPIAI_01048 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
OLEDPIAI_01049 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
OLEDPIAI_01050 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OLEDPIAI_01051 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OLEDPIAI_01052 0.0 ydiF S ABC transporter
OLEDPIAI_01053 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OLEDPIAI_01054 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OLEDPIAI_01055 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OLEDPIAI_01056 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OLEDPIAI_01057 2.9e-27 ydiK S Domain of unknown function (DUF4305)
OLEDPIAI_01058 7.9e-129 ydiL S CAAX protease self-immunity
OLEDPIAI_01059 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OLEDPIAI_01060 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OLEDPIAI_01062 6.4e-66 KL Phage plasmid primase P4 family
OLEDPIAI_01063 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
OLEDPIAI_01064 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
OLEDPIAI_01066 1.2e-199 V AAA domain (dynein-related subfamily)
OLEDPIAI_01067 4.9e-257 J LlaJI restriction endonuclease
OLEDPIAI_01068 1.1e-08 ydjC S Abhydrolase domain containing 18
OLEDPIAI_01069 0.0 K NB-ARC domain
OLEDPIAI_01070 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
OLEDPIAI_01071 7.1e-256 gutA G MFS/sugar transport protein
OLEDPIAI_01072 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
OLEDPIAI_01073 5.1e-114 pspA KT Phage shock protein A
OLEDPIAI_01074 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OLEDPIAI_01075 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
OLEDPIAI_01076 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
OLEDPIAI_01077 4.7e-196 S Ion transport 2 domain protein
OLEDPIAI_01078 2.7e-258 iolT EGP Major facilitator Superfamily
OLEDPIAI_01079 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OLEDPIAI_01080 4.5e-64 ydjM M Lytic transglycolase
OLEDPIAI_01081 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
OLEDPIAI_01083 1.4e-34 ydjO S Cold-inducible protein YdjO
OLEDPIAI_01084 9.5e-160 ydjP I Alpha/beta hydrolase family
OLEDPIAI_01085 2.4e-181 yeaA S Protein of unknown function (DUF4003)
OLEDPIAI_01086 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OLEDPIAI_01087 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
OLEDPIAI_01088 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OLEDPIAI_01089 1.6e-177 yeaC S COG0714 MoxR-like ATPases
OLEDPIAI_01090 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
OLEDPIAI_01091 0.0 yebA E COG1305 Transglutaminase-like enzymes
OLEDPIAI_01092 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OLEDPIAI_01093 6e-212 pbuG S permease
OLEDPIAI_01094 1.1e-118 yebC M Membrane
OLEDPIAI_01096 4e-93 yebE S UPF0316 protein
OLEDPIAI_01097 8e-28 yebG S NETI protein
OLEDPIAI_01098 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OLEDPIAI_01099 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OLEDPIAI_01100 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OLEDPIAI_01101 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OLEDPIAI_01102 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OLEDPIAI_01103 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OLEDPIAI_01104 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OLEDPIAI_01105 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OLEDPIAI_01106 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OLEDPIAI_01107 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OLEDPIAI_01108 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OLEDPIAI_01109 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
OLEDPIAI_01110 3.5e-73 K helix_turn_helix ASNC type
OLEDPIAI_01111 2.3e-232 yjeH E Amino acid permease
OLEDPIAI_01112 2.7e-27 S Protein of unknown function (DUF2892)
OLEDPIAI_01113 0.0 yerA 3.5.4.2 F adenine deaminase
OLEDPIAI_01114 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
OLEDPIAI_01115 4.8e-51 yerC S protein conserved in bacteria
OLEDPIAI_01116 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
OLEDPIAI_01118 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OLEDPIAI_01119 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OLEDPIAI_01120 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OLEDPIAI_01121 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
OLEDPIAI_01122 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
OLEDPIAI_01123 1.6e-123 sapB S MgtC SapB transporter
OLEDPIAI_01124 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OLEDPIAI_01125 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OLEDPIAI_01126 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OLEDPIAI_01127 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OLEDPIAI_01128 4e-156 yerO K Transcriptional regulator
OLEDPIAI_01129 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OLEDPIAI_01130 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OLEDPIAI_01131 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OLEDPIAI_01132 3.2e-98 L Recombinase
OLEDPIAI_01133 3.2e-53 L Resolvase, N terminal domain
OLEDPIAI_01134 0.0 yeeA V Type II restriction enzyme, methylase subunits
OLEDPIAI_01135 0.0 yeeB L DEAD-like helicases superfamily
OLEDPIAI_01136 1.2e-211 pstS P T5orf172
OLEDPIAI_01138 6.2e-31 S Colicin immunity protein / pyocin immunity protein
OLEDPIAI_01139 5.5e-83 S Protein of unknown function, DUF600
OLEDPIAI_01140 0.0 L nucleic acid phosphodiester bond hydrolysis
OLEDPIAI_01141 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
OLEDPIAI_01142 5.5e-214 S Tetratricopeptide repeat
OLEDPIAI_01144 9.4e-127 yeeN K transcriptional regulatory protein
OLEDPIAI_01146 1.2e-103 dhaR3 K Transcriptional regulator
OLEDPIAI_01147 9.7e-82 yesE S SnoaL-like domain
OLEDPIAI_01148 2.2e-159 yesF GM NAD(P)H-binding
OLEDPIAI_01149 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
OLEDPIAI_01150 1.5e-45 cotJB S CotJB protein
OLEDPIAI_01151 5.2e-104 cotJC P Spore Coat
OLEDPIAI_01152 4.2e-103 yesJ K Acetyltransferase (GNAT) family
OLEDPIAI_01154 4.4e-104 yesL S Protein of unknown function, DUF624
OLEDPIAI_01155 0.0 yesM 2.7.13.3 T Histidine kinase
OLEDPIAI_01156 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
OLEDPIAI_01157 5e-248 yesO G Bacterial extracellular solute-binding protein
OLEDPIAI_01158 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
OLEDPIAI_01159 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
OLEDPIAI_01160 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
OLEDPIAI_01161 0.0 yesS K Transcriptional regulator
OLEDPIAI_01162 3.8e-133 E GDSL-like Lipase/Acylhydrolase
OLEDPIAI_01163 8.9e-132 yesU S Domain of unknown function (DUF1961)
OLEDPIAI_01164 1e-113 yesV S Protein of unknown function, DUF624
OLEDPIAI_01165 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
OLEDPIAI_01166 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
OLEDPIAI_01167 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
OLEDPIAI_01168 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
OLEDPIAI_01169 0.0 yetA
OLEDPIAI_01170 9.6e-291 lplA G Bacterial extracellular solute-binding protein
OLEDPIAI_01171 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
OLEDPIAI_01172 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
OLEDPIAI_01173 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OLEDPIAI_01174 6.1e-123 yetF S membrane
OLEDPIAI_01175 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
OLEDPIAI_01176 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLEDPIAI_01177 2.2e-34
OLEDPIAI_01178 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OLEDPIAI_01179 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OLEDPIAI_01180 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
OLEDPIAI_01181 5.3e-105 yetJ S Belongs to the BI1 family
OLEDPIAI_01182 5.4e-159 yetK EG EamA-like transporter family
OLEDPIAI_01183 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
OLEDPIAI_01184 7.8e-213 yetM CH FAD binding domain
OLEDPIAI_01185 3.6e-199 yetN S Protein of unknown function (DUF3900)
OLEDPIAI_01186 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OLEDPIAI_01187 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OLEDPIAI_01188 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
OLEDPIAI_01189 1.9e-172 yfnG 4.2.1.45 M dehydratase
OLEDPIAI_01190 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
OLEDPIAI_01191 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
OLEDPIAI_01192 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
OLEDPIAI_01193 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
OLEDPIAI_01194 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OLEDPIAI_01195 1.3e-241 yfnA E amino acid
OLEDPIAI_01196 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OLEDPIAI_01197 1.1e-113 yfmS NT chemotaxis protein
OLEDPIAI_01198 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OLEDPIAI_01199 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
OLEDPIAI_01200 2.8e-70 yfmP K transcriptional
OLEDPIAI_01201 1.5e-209 yfmO EGP Major facilitator Superfamily
OLEDPIAI_01202 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OLEDPIAI_01203 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
OLEDPIAI_01204 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
OLEDPIAI_01205 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
OLEDPIAI_01206 7.7e-214 G Major Facilitator Superfamily
OLEDPIAI_01207 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
OLEDPIAI_01208 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
OLEDPIAI_01209 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_01210 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_01211 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
OLEDPIAI_01212 2.9e-24 S Protein of unknown function (DUF3212)
OLEDPIAI_01213 7.6e-58 yflT S Heat induced stress protein YflT
OLEDPIAI_01214 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
OLEDPIAI_01215 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
OLEDPIAI_01216 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OLEDPIAI_01217 8.9e-119 citT T response regulator
OLEDPIAI_01218 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
OLEDPIAI_01220 8.5e-227 citM C Citrate transporter
OLEDPIAI_01221 2.7e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
OLEDPIAI_01222 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OLEDPIAI_01223 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OLEDPIAI_01224 9e-124 yflK S protein conserved in bacteria
OLEDPIAI_01225 4e-18 yflJ S Protein of unknown function (DUF2639)
OLEDPIAI_01226 4.1e-19 yflI
OLEDPIAI_01227 2.4e-50 yflH S Protein of unknown function (DUF3243)
OLEDPIAI_01228 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
OLEDPIAI_01229 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
OLEDPIAI_01230 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OLEDPIAI_01231 6e-67 yhdN S Domain of unknown function (DUF1992)
OLEDPIAI_01232 3.2e-256 agcS_1 E Sodium alanine symporter
OLEDPIAI_01233 1.6e-194 E Spore germination protein
OLEDPIAI_01235 5.1e-207 yfkR S spore germination
OLEDPIAI_01236 1.5e-283 yfkQ EG Spore germination protein
OLEDPIAI_01237 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLEDPIAI_01238 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OLEDPIAI_01239 1.8e-133 treR K transcriptional
OLEDPIAI_01240 1.6e-125 yfkO C nitroreductase
OLEDPIAI_01241 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OLEDPIAI_01242 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
OLEDPIAI_01243 6.8e-207 ydiM EGP Major facilitator Superfamily
OLEDPIAI_01244 2.1e-29 yfkK S Belongs to the UPF0435 family
OLEDPIAI_01245 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OLEDPIAI_01246 8.4e-51 yfkI S gas vesicle protein
OLEDPIAI_01247 9.7e-144 yihY S Belongs to the UPF0761 family
OLEDPIAI_01248 5e-08
OLEDPIAI_01249 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
OLEDPIAI_01250 6.1e-183 cax P COG0387 Ca2 H antiporter
OLEDPIAI_01251 1.2e-146 yfkD S YfkD-like protein
OLEDPIAI_01252 6e-149 yfkC M Mechanosensitive ion channel
OLEDPIAI_01253 5.4e-222 yfkA S YfkB-like domain
OLEDPIAI_01254 1.1e-26 yfjT
OLEDPIAI_01255 2.6e-154 pdaA G deacetylase
OLEDPIAI_01256 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
OLEDPIAI_01257 1.7e-184 corA P Mediates influx of magnesium ions
OLEDPIAI_01258 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OLEDPIAI_01259 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OLEDPIAI_01260 1.6e-39 S YfzA-like protein
OLEDPIAI_01261 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OLEDPIAI_01262 3.9e-86 yfjM S Psort location Cytoplasmic, score
OLEDPIAI_01263 3e-29 yfjL
OLEDPIAI_01264 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OLEDPIAI_01265 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OLEDPIAI_01266 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OLEDPIAI_01267 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OLEDPIAI_01268 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OLEDPIAI_01269 1.2e-25 sspH S Belongs to the SspH family
OLEDPIAI_01270 4e-56 yfjF S UPF0060 membrane protein
OLEDPIAI_01271 1.3e-80 S Family of unknown function (DUF5381)
OLEDPIAI_01272 1.8e-101 yfjD S Family of unknown function (DUF5381)
OLEDPIAI_01273 4.1e-144 yfjC
OLEDPIAI_01274 9.2e-191 yfjB
OLEDPIAI_01275 1.1e-44 yfjA S Belongs to the WXG100 family
OLEDPIAI_01276 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OLEDPIAI_01277 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
OLEDPIAI_01278 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLEDPIAI_01279 2.1e-310 yfiB3 V ABC transporter
OLEDPIAI_01280 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
OLEDPIAI_01281 9.8e-65 mhqP S DoxX
OLEDPIAI_01282 5.7e-163 yfiE 1.13.11.2 S glyoxalase
OLEDPIAI_01283 1.5e-177 K AraC-like ligand binding domain
OLEDPIAI_01284 1.8e-262 iolT EGP Major facilitator Superfamily
OLEDPIAI_01285 8.4e-184 G Xylose isomerase
OLEDPIAI_01286 1.1e-233 S Oxidoreductase
OLEDPIAI_01288 1.1e-214 yxjM T Histidine kinase
OLEDPIAI_01289 3.2e-113 KT LuxR family transcriptional regulator
OLEDPIAI_01290 6.2e-171 V ABC transporter, ATP-binding protein
OLEDPIAI_01291 9.8e-214 V ABC-2 family transporter protein
OLEDPIAI_01292 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
OLEDPIAI_01293 8.3e-99 padR K transcriptional
OLEDPIAI_01294 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OLEDPIAI_01295 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OLEDPIAI_01296 2e-109 yfiR K Transcriptional regulator
OLEDPIAI_01297 5.1e-221 yfiS EGP Major facilitator Superfamily
OLEDPIAI_01298 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
OLEDPIAI_01299 8.7e-287 yfiU EGP Major facilitator Superfamily
OLEDPIAI_01300 3.1e-81 yfiV K transcriptional
OLEDPIAI_01301 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OLEDPIAI_01302 6.2e-182 yfiY P ABC transporter substrate-binding protein
OLEDPIAI_01303 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_01304 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_01305 1.8e-167 yfhB 5.3.3.17 S PhzF family
OLEDPIAI_01306 3.9e-107 yfhC C nitroreductase
OLEDPIAI_01307 2.1e-25 yfhD S YfhD-like protein
OLEDPIAI_01309 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
OLEDPIAI_01310 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
OLEDPIAI_01311 9.7e-52 yfhH S Protein of unknown function (DUF1811)
OLEDPIAI_01313 1.1e-209 yfhI EGP Major facilitator Superfamily
OLEDPIAI_01314 6.2e-20 sspK S reproduction
OLEDPIAI_01315 1.3e-44 yfhJ S WVELL protein
OLEDPIAI_01316 9.2e-92 batE T Bacterial SH3 domain homologues
OLEDPIAI_01317 3.5e-51 yfhL S SdpI/YhfL protein family
OLEDPIAI_01318 6.7e-172 yfhM S Alpha beta hydrolase
OLEDPIAI_01319 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OLEDPIAI_01320 0.0 yfhO S Bacterial membrane protein YfhO
OLEDPIAI_01321 5.5e-186 yfhP S membrane-bound metal-dependent
OLEDPIAI_01322 7.8e-212 mutY L A G-specific
OLEDPIAI_01323 6.9e-36 yfhS
OLEDPIAI_01324 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLEDPIAI_01325 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
OLEDPIAI_01326 1.5e-37 ygaB S YgaB-like protein
OLEDPIAI_01327 1.3e-104 ygaC J Belongs to the UPF0374 family
OLEDPIAI_01328 1.8e-301 ygaD V ABC transporter
OLEDPIAI_01329 8.7e-180 ygaE S Membrane
OLEDPIAI_01330 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OLEDPIAI_01331 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
OLEDPIAI_01332 4e-80 perR P Belongs to the Fur family
OLEDPIAI_01333 1.5e-56 ygzB S UPF0295 protein
OLEDPIAI_01334 6.7e-167 ygxA S Nucleotidyltransferase-like
OLEDPIAI_01337 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
OLEDPIAI_01338 8.7e-30 cspL K Cold shock
OLEDPIAI_01339 6.1e-79 carD K Transcription factor
OLEDPIAI_01340 4.6e-35 ydzE EG spore germination
OLEDPIAI_01341 1.1e-166 rhaS5 K AraC-like ligand binding domain
OLEDPIAI_01342 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OLEDPIAI_01343 2.5e-166 ydeE K AraC family transcriptional regulator
OLEDPIAI_01344 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLEDPIAI_01345 3.4e-220 ydeG EGP Major facilitator superfamily
OLEDPIAI_01346 2.9e-47 ydeH
OLEDPIAI_01347 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
OLEDPIAI_01348 4e-116
OLEDPIAI_01349 1.8e-153 ydeK EG -transporter
OLEDPIAI_01350 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLEDPIAI_01351 4.2e-74 maoC I N-terminal half of MaoC dehydratase
OLEDPIAI_01352 8.6e-107 ydeN S Serine hydrolase
OLEDPIAI_01353 1.1e-58 K HxlR-like helix-turn-helix
OLEDPIAI_01354 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OLEDPIAI_01355 4.8e-69 ydeP K Transcriptional regulator
OLEDPIAI_01356 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
OLEDPIAI_01357 1.2e-195 ydeR EGP Major facilitator Superfamily
OLEDPIAI_01358 8.4e-105 ydeS K Transcriptional regulator
OLEDPIAI_01359 1.3e-57 arsR K transcriptional
OLEDPIAI_01360 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OLEDPIAI_01361 7.2e-149 ydfB J GNAT acetyltransferase
OLEDPIAI_01362 1e-162 ydfC EG EamA-like transporter family
OLEDPIAI_01363 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLEDPIAI_01364 5.9e-117 ydfE S Flavin reductase like domain
OLEDPIAI_01365 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
OLEDPIAI_01366 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OLEDPIAI_01368 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
OLEDPIAI_01369 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLEDPIAI_01370 0.0 ydfJ S drug exporters of the RND superfamily
OLEDPIAI_01371 1.9e-177 S Alpha/beta hydrolase family
OLEDPIAI_01372 5.9e-118 S Protein of unknown function (DUF554)
OLEDPIAI_01373 3.2e-147 K Bacterial transcription activator, effector binding domain
OLEDPIAI_01374 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OLEDPIAI_01375 9.6e-112 ydfN C nitroreductase
OLEDPIAI_01376 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
OLEDPIAI_01377 8.8e-63 mhqP S DoxX
OLEDPIAI_01378 1.3e-57 traF CO Thioredoxin
OLEDPIAI_01379 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
OLEDPIAI_01380 6.3e-29
OLEDPIAI_01382 4.4e-118 ydfR S Protein of unknown function (DUF421)
OLEDPIAI_01383 5.2e-122 ydfS S Protein of unknown function (DUF421)
OLEDPIAI_01384 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
OLEDPIAI_01385 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
OLEDPIAI_01386 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
OLEDPIAI_01387 1.5e-101 K Bacterial regulatory proteins, tetR family
OLEDPIAI_01388 7.3e-53 S DoxX-like family
OLEDPIAI_01389 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
OLEDPIAI_01390 4.2e-308 expZ S ABC transporter
OLEDPIAI_01391 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
OLEDPIAI_01392 4.6e-91 dinB S DinB family
OLEDPIAI_01393 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
OLEDPIAI_01394 0.0 ydgH S drug exporters of the RND superfamily
OLEDPIAI_01395 1e-113 drgA C nitroreductase
OLEDPIAI_01396 1.1e-69 ydgJ K Winged helix DNA-binding domain
OLEDPIAI_01397 2.5e-209 tcaB EGP Major facilitator Superfamily
OLEDPIAI_01398 1.2e-121 ydhB S membrane transporter protein
OLEDPIAI_01399 6.5e-122 ydhC K FCD
OLEDPIAI_01400 3.3e-244 ydhD M Glycosyl hydrolase
OLEDPIAI_01401 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OLEDPIAI_01402 1.9e-127
OLEDPIAI_01403 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OLEDPIAI_01404 4.6e-69 frataxin S Domain of unknown function (DU1801)
OLEDPIAI_01406 4.1e-86 K Acetyltransferase (GNAT) domain
OLEDPIAI_01407 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
OLEDPIAI_01408 1.7e-99 ydhK M Protein of unknown function (DUF1541)
OLEDPIAI_01409 4.6e-200 pbuE EGP Major facilitator Superfamily
OLEDPIAI_01410 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
OLEDPIAI_01411 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
OLEDPIAI_01412 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OLEDPIAI_01413 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OLEDPIAI_01414 3.9e-133 ydhQ K UTRA
OLEDPIAI_01415 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
OLEDPIAI_01416 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
OLEDPIAI_01417 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
OLEDPIAI_01418 8.7e-78 ydhU P Catalase
OLEDPIAI_01419 1.1e-16 ydhU P Manganese containing catalase
OLEDPIAI_01422 3.4e-39 S COG NOG14552 non supervised orthologous group
OLEDPIAI_01423 3.4e-31 csfB S Inhibitor of sigma-G Gin
OLEDPIAI_01424 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
OLEDPIAI_01425 4.5e-203 yaaN P Belongs to the TelA family
OLEDPIAI_01426 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
OLEDPIAI_01427 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OLEDPIAI_01428 2.2e-54 yaaQ S protein conserved in bacteria
OLEDPIAI_01429 1.5e-71 yaaR S protein conserved in bacteria
OLEDPIAI_01430 2.2e-182 holB 2.7.7.7 L DNA polymerase III
OLEDPIAI_01431 2.1e-146 yaaT S stage 0 sporulation protein
OLEDPIAI_01432 4.8e-31 yabA L Involved in initiation control of chromosome replication
OLEDPIAI_01433 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
OLEDPIAI_01434 1.5e-49 yazA L endonuclease containing a URI domain
OLEDPIAI_01435 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OLEDPIAI_01436 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
OLEDPIAI_01437 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OLEDPIAI_01438 1.8e-144 tatD L hydrolase, TatD
OLEDPIAI_01439 4.3e-194 rpfB GH23 T protein conserved in bacteria
OLEDPIAI_01440 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OLEDPIAI_01441 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OLEDPIAI_01442 3.3e-137 yabG S peptidase
OLEDPIAI_01443 7.8e-39 veg S protein conserved in bacteria
OLEDPIAI_01444 8.3e-27 sspF S DNA topological change
OLEDPIAI_01445 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OLEDPIAI_01446 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OLEDPIAI_01447 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
OLEDPIAI_01448 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OLEDPIAI_01449 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OLEDPIAI_01450 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OLEDPIAI_01451 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OLEDPIAI_01452 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OLEDPIAI_01453 2.4e-39 yabK S Peptide ABC transporter permease
OLEDPIAI_01454 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OLEDPIAI_01455 1.5e-92 spoVT K stage V sporulation protein
OLEDPIAI_01456 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLEDPIAI_01457 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OLEDPIAI_01458 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OLEDPIAI_01459 1.5e-49 yabP S Sporulation protein YabP
OLEDPIAI_01460 3.9e-108 yabQ S spore cortex biosynthesis protein
OLEDPIAI_01461 1.1e-44 divIC D Septum formation initiator
OLEDPIAI_01462 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
OLEDPIAI_01465 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
OLEDPIAI_01466 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
OLEDPIAI_01467 6.7e-187 KLT serine threonine protein kinase
OLEDPIAI_01468 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OLEDPIAI_01469 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OLEDPIAI_01470 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OLEDPIAI_01471 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OLEDPIAI_01472 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OLEDPIAI_01473 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
OLEDPIAI_01474 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OLEDPIAI_01475 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OLEDPIAI_01476 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
OLEDPIAI_01477 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
OLEDPIAI_01478 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OLEDPIAI_01479 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OLEDPIAI_01480 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OLEDPIAI_01481 4.1e-30 yazB K transcriptional
OLEDPIAI_01482 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OLEDPIAI_01483 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OLEDPIAI_01488 7.8e-08
OLEDPIAI_01496 2e-08
OLEDPIAI_01500 2.7e-143 spo0M S COG4326 Sporulation control protein
OLEDPIAI_01501 3e-27
OLEDPIAI_01502 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
OLEDPIAI_01503 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OLEDPIAI_01504 1.9e-266 ygaK C Berberine and berberine like
OLEDPIAI_01506 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OLEDPIAI_01507 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
OLEDPIAI_01508 1.7e-171 ssuA M Sulfonate ABC transporter
OLEDPIAI_01509 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OLEDPIAI_01510 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
OLEDPIAI_01512 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OLEDPIAI_01513 4.1e-78 ygaO
OLEDPIAI_01514 4.4e-29 K Transcriptional regulator
OLEDPIAI_01516 7.9e-114 yhzB S B3/4 domain
OLEDPIAI_01517 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OLEDPIAI_01518 4.4e-177 yhbB S Putative amidase domain
OLEDPIAI_01519 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OLEDPIAI_01520 1.2e-109 yhbD K Protein of unknown function (DUF4004)
OLEDPIAI_01521 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
OLEDPIAI_01522 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
OLEDPIAI_01523 0.0 prkA T Ser protein kinase
OLEDPIAI_01524 2.5e-225 yhbH S Belongs to the UPF0229 family
OLEDPIAI_01525 2.2e-76 yhbI K DNA-binding transcription factor activity
OLEDPIAI_01526 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
OLEDPIAI_01527 3.1e-271 yhcA EGP Major facilitator Superfamily
OLEDPIAI_01528 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
OLEDPIAI_01529 2.8e-37 yhcC
OLEDPIAI_01530 7.8e-55
OLEDPIAI_01531 6.6e-60 yhcF K Transcriptional regulator
OLEDPIAI_01532 1.6e-123 yhcG V ABC transporter, ATP-binding protein
OLEDPIAI_01533 2.6e-166 yhcH V ABC transporter, ATP-binding protein
OLEDPIAI_01534 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OLEDPIAI_01535 1e-30 cspB K Cold-shock protein
OLEDPIAI_01536 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
OLEDPIAI_01537 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
OLEDPIAI_01538 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OLEDPIAI_01539 3.7e-44 yhcM
OLEDPIAI_01540 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OLEDPIAI_01541 2.5e-167 yhcP
OLEDPIAI_01542 5.2e-100 yhcQ M Spore coat protein
OLEDPIAI_01543 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
OLEDPIAI_01544 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
OLEDPIAI_01545 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OLEDPIAI_01546 9.3e-68 yhcU S Family of unknown function (DUF5365)
OLEDPIAI_01547 9.9e-68 yhcV S COG0517 FOG CBS domain
OLEDPIAI_01548 4.6e-120 yhcW 5.4.2.6 S hydrolase
OLEDPIAI_01549 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OLEDPIAI_01550 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OLEDPIAI_01551 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OLEDPIAI_01552 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
OLEDPIAI_01553 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OLEDPIAI_01554 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OLEDPIAI_01555 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OLEDPIAI_01556 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
OLEDPIAI_01557 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLEDPIAI_01558 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
OLEDPIAI_01559 1.2e-38 yhdB S YhdB-like protein
OLEDPIAI_01560 4.8e-54 yhdC S Protein of unknown function (DUF3889)
OLEDPIAI_01561 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OLEDPIAI_01562 3.5e-76 nsrR K Transcriptional regulator
OLEDPIAI_01563 8.7e-239 ygxB M Conserved TM helix
OLEDPIAI_01564 2.1e-276 ycgB S Stage V sporulation protein R
OLEDPIAI_01565 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OLEDPIAI_01566 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OLEDPIAI_01567 3.8e-162 citR K Transcriptional regulator
OLEDPIAI_01568 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
OLEDPIAI_01569 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLEDPIAI_01570 3.4e-250 yhdG E amino acid
OLEDPIAI_01571 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OLEDPIAI_01572 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLEDPIAI_01573 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLEDPIAI_01574 8.1e-45 yhdK S Sigma-M inhibitor protein
OLEDPIAI_01575 6.6e-201 yhdL S Sigma factor regulator N-terminal
OLEDPIAI_01576 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
OLEDPIAI_01577 1.5e-191 yhdN C Aldo keto reductase
OLEDPIAI_01578 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OLEDPIAI_01579 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OLEDPIAI_01580 4.1e-74 cueR K transcriptional
OLEDPIAI_01581 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
OLEDPIAI_01582 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
OLEDPIAI_01583 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OLEDPIAI_01584 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OLEDPIAI_01585 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OLEDPIAI_01587 6.6e-204 yhdY M Mechanosensitive ion channel
OLEDPIAI_01588 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OLEDPIAI_01589 1.7e-151 yheN G deacetylase
OLEDPIAI_01590 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OLEDPIAI_01591 2.2e-233 nhaC C Na H antiporter
OLEDPIAI_01592 3.4e-84 nhaX T Belongs to the universal stress protein A family
OLEDPIAI_01593 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
OLEDPIAI_01594 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
OLEDPIAI_01595 3.7e-111 yheG GM NAD(P)H-binding
OLEDPIAI_01596 6.3e-28 sspB S spore protein
OLEDPIAI_01597 1.3e-36 yheE S Family of unknown function (DUF5342)
OLEDPIAI_01598 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OLEDPIAI_01599 4.3e-216 yheC HJ YheC/D like ATP-grasp
OLEDPIAI_01600 6.7e-204 yheB S Belongs to the UPF0754 family
OLEDPIAI_01601 9.5e-48 yheA S Belongs to the UPF0342 family
OLEDPIAI_01602 3.1e-206 yhaZ L DNA alkylation repair enzyme
OLEDPIAI_01603 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
OLEDPIAI_01604 7.1e-294 hemZ H coproporphyrinogen III oxidase
OLEDPIAI_01605 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
OLEDPIAI_01606 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
OLEDPIAI_01608 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
OLEDPIAI_01609 1.1e-26 S YhzD-like protein
OLEDPIAI_01610 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
OLEDPIAI_01611 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
OLEDPIAI_01612 3.6e-227 yhaO L DNA repair exonuclease
OLEDPIAI_01613 0.0 yhaN L AAA domain
OLEDPIAI_01614 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
OLEDPIAI_01615 1.6e-21 yhaL S Sporulation protein YhaL
OLEDPIAI_01616 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OLEDPIAI_01617 8.7e-90 yhaK S Putative zincin peptidase
OLEDPIAI_01618 1.3e-54 yhaI S Protein of unknown function (DUF1878)
OLEDPIAI_01619 1e-113 hpr K Negative regulator of protease production and sporulation
OLEDPIAI_01620 7e-39 yhaH S YtxH-like protein
OLEDPIAI_01621 3.6e-80 trpP S Tryptophan transporter TrpP
OLEDPIAI_01622 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OLEDPIAI_01623 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OLEDPIAI_01624 4.6e-137 ecsA V transporter (ATP-binding protein)
OLEDPIAI_01625 1.8e-215 ecsB U ABC transporter
OLEDPIAI_01626 4.8e-115 ecsC S EcsC protein family
OLEDPIAI_01627 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OLEDPIAI_01628 4.2e-248 yhfA C membrane
OLEDPIAI_01629 7.5e-17 1.15.1.2 C Rubrerythrin
OLEDPIAI_01630 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
OLEDPIAI_01631 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OLEDPIAI_01632 2.4e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OLEDPIAI_01633 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OLEDPIAI_01634 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OLEDPIAI_01635 1.4e-101 yhgD K Transcriptional regulator
OLEDPIAI_01636 1e-238 yhgE S YhgE Pip N-terminal domain protein
OLEDPIAI_01637 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OLEDPIAI_01638 5.2e-50 yhfC S Putative membrane peptidase family (DUF2324)
OLEDPIAI_01639 2.4e-78 yhfC S Putative membrane peptidase family (DUF2324)
OLEDPIAI_01640 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
OLEDPIAI_01641 1.7e-72 3.4.13.21 S ASCH
OLEDPIAI_01642 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OLEDPIAI_01643 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
OLEDPIAI_01644 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
OLEDPIAI_01645 2.6e-112 yhfK GM NmrA-like family
OLEDPIAI_01646 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OLEDPIAI_01647 1.9e-65 yhfM
OLEDPIAI_01648 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
OLEDPIAI_01649 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
OLEDPIAI_01650 9.2e-80 VY92_01935 K acetyltransferase
OLEDPIAI_01651 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
OLEDPIAI_01652 4.3e-159 yfmC M Periplasmic binding protein
OLEDPIAI_01653 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
OLEDPIAI_01654 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
OLEDPIAI_01655 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OLEDPIAI_01656 5e-91 bioY S BioY family
OLEDPIAI_01657 1.7e-182 hemAT NT chemotaxis protein
OLEDPIAI_01658 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OLEDPIAI_01659 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLEDPIAI_01660 1.3e-32 yhzC S IDEAL
OLEDPIAI_01661 4.2e-109 comK K Competence transcription factor
OLEDPIAI_01662 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
OLEDPIAI_01663 7.8e-42 yhjA S Excalibur calcium-binding domain
OLEDPIAI_01664 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OLEDPIAI_01665 6.9e-27 yhjC S Protein of unknown function (DUF3311)
OLEDPIAI_01666 5e-60 yhjD
OLEDPIAI_01667 9.1e-110 yhjE S SNARE associated Golgi protein
OLEDPIAI_01668 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
OLEDPIAI_01669 1.1e-286 yhjG CH FAD binding domain
OLEDPIAI_01670 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
OLEDPIAI_01671 6.9e-215 glcP G Major Facilitator Superfamily
OLEDPIAI_01672 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
OLEDPIAI_01673 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
OLEDPIAI_01674 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
OLEDPIAI_01675 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
OLEDPIAI_01676 3.8e-202 abrB S membrane
OLEDPIAI_01677 3.1e-215 EGP Transmembrane secretion effector
OLEDPIAI_01678 0.0 S Sugar transport-related sRNA regulator N-term
OLEDPIAI_01679 2e-36 yhjQ C COG1145 Ferredoxin
OLEDPIAI_01680 2.2e-78 yhjR S Rubrerythrin
OLEDPIAI_01681 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
OLEDPIAI_01682 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OLEDPIAI_01683 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OLEDPIAI_01684 0.0 sbcC L COG0419 ATPase involved in DNA repair
OLEDPIAI_01685 6e-51 yisB V COG1403 Restriction endonuclease
OLEDPIAI_01686 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
OLEDPIAI_01687 3e-66 gerPE S Spore germination protein GerPE
OLEDPIAI_01688 6.3e-24 gerPD S Spore germination protein
OLEDPIAI_01689 1.8e-54 gerPC S Spore germination protein
OLEDPIAI_01690 4e-34 gerPB S cell differentiation
OLEDPIAI_01691 1.9e-33 gerPA S Spore germination protein
OLEDPIAI_01692 1.5e-22 yisI S Spo0E like sporulation regulatory protein
OLEDPIAI_01693 1.7e-176 cotH M Spore Coat
OLEDPIAI_01694 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OLEDPIAI_01695 3e-57 yisL S UPF0344 protein
OLEDPIAI_01696 0.0 wprA O Belongs to the peptidase S8 family
OLEDPIAI_01697 7.2e-106 yisN S Protein of unknown function (DUF2777)
OLEDPIAI_01698 0.0 asnO 6.3.5.4 E Asparagine synthase
OLEDPIAI_01699 2.1e-88 yizA S Damage-inducible protein DinB
OLEDPIAI_01700 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
OLEDPIAI_01701 4e-243 yisQ V Mate efflux family protein
OLEDPIAI_01702 1.2e-160 yisR K Transcriptional regulator
OLEDPIAI_01703 2.4e-184 purR K helix_turn _helix lactose operon repressor
OLEDPIAI_01704 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
OLEDPIAI_01705 1.3e-93 yisT S DinB family
OLEDPIAI_01706 6.4e-108 argO S Lysine exporter protein LysE YggA
OLEDPIAI_01707 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLEDPIAI_01708 4e-36 mcbG S Pentapeptide repeats (9 copies)
OLEDPIAI_01709 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OLEDPIAI_01710 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
OLEDPIAI_01711 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OLEDPIAI_01712 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OLEDPIAI_01713 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
OLEDPIAI_01714 1.9e-141 yitD 4.4.1.19 S synthase
OLEDPIAI_01715 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OLEDPIAI_01716 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OLEDPIAI_01717 4e-229 yitG EGP Major facilitator Superfamily
OLEDPIAI_01718 1.8e-161 yitH K Acetyltransferase (GNAT) domain
OLEDPIAI_01719 5.8e-82 yjcF S Acetyltransferase (GNAT) domain
OLEDPIAI_01720 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OLEDPIAI_01721 8.6e-55 yajQ S Belongs to the UPF0234 family
OLEDPIAI_01722 4e-161 cvfB S protein conserved in bacteria
OLEDPIAI_01723 8.5e-94
OLEDPIAI_01724 2.8e-171
OLEDPIAI_01725 1.5e-97 S Sporulation delaying protein SdpA
OLEDPIAI_01726 1.5e-58 K Transcriptional regulator PadR-like family
OLEDPIAI_01727 2e-95
OLEDPIAI_01728 1.4e-44 yitR S Domain of unknown function (DUF3784)
OLEDPIAI_01729 2.2e-311 nprB 3.4.24.28 E Peptidase M4
OLEDPIAI_01730 8.4e-159 yitS S protein conserved in bacteria
OLEDPIAI_01731 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
OLEDPIAI_01732 1.9e-72 ipi S Intracellular proteinase inhibitor
OLEDPIAI_01733 1.2e-17 S Protein of unknown function (DUF3813)
OLEDPIAI_01734 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
OLEDPIAI_01735 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
OLEDPIAI_01736 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
OLEDPIAI_01737 1.5e-22 pilT S Proteolipid membrane potential modulator
OLEDPIAI_01738 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
OLEDPIAI_01739 1.7e-88 norB G Major Facilitator Superfamily
OLEDPIAI_01740 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OLEDPIAI_01741 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OLEDPIAI_01742 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
OLEDPIAI_01743 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OLEDPIAI_01744 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OLEDPIAI_01745 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
OLEDPIAI_01746 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OLEDPIAI_01747 9.5e-28 yjzC S YjzC-like protein
OLEDPIAI_01748 2.3e-16 yjzD S Protein of unknown function (DUF2929)
OLEDPIAI_01749 6.2e-142 yjaU I carboxylic ester hydrolase activity
OLEDPIAI_01750 7.3e-103 yjaV
OLEDPIAI_01751 1.1e-183 med S Transcriptional activator protein med
OLEDPIAI_01752 7.3e-26 comZ S ComZ
OLEDPIAI_01753 2.7e-22 yjzB
OLEDPIAI_01754 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OLEDPIAI_01755 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OLEDPIAI_01756 7.8e-151 yjaZ O Zn-dependent protease
OLEDPIAI_01757 1.8e-184 appD P Belongs to the ABC transporter superfamily
OLEDPIAI_01758 6.5e-187 appF E Belongs to the ABC transporter superfamily
OLEDPIAI_01759 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
OLEDPIAI_01760 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLEDPIAI_01761 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLEDPIAI_01762 5e-147 yjbA S Belongs to the UPF0736 family
OLEDPIAI_01763 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OLEDPIAI_01764 0.0 oppA E ABC transporter substrate-binding protein
OLEDPIAI_01765 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLEDPIAI_01766 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLEDPIAI_01767 3e-198 oppD P Belongs to the ABC transporter superfamily
OLEDPIAI_01768 5.5e-172 oppF E Belongs to the ABC transporter superfamily
OLEDPIAI_01769 8.6e-196 yjbB EGP Major Facilitator Superfamily
OLEDPIAI_01770 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLEDPIAI_01771 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OLEDPIAI_01772 6e-112 yjbE P Integral membrane protein TerC family
OLEDPIAI_01773 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OLEDPIAI_01774 2.3e-223 yjbF S Competence protein
OLEDPIAI_01775 0.0 pepF E oligoendopeptidase F
OLEDPIAI_01776 1.8e-20
OLEDPIAI_01778 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OLEDPIAI_01779 3.7e-72 yjbI S Bacterial-like globin
OLEDPIAI_01780 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OLEDPIAI_01781 2.4e-101 yjbK S protein conserved in bacteria
OLEDPIAI_01782 7.1e-62 yjbL S Belongs to the UPF0738 family
OLEDPIAI_01783 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
OLEDPIAI_01784 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OLEDPIAI_01785 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OLEDPIAI_01786 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OLEDPIAI_01787 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OLEDPIAI_01788 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OLEDPIAI_01789 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
OLEDPIAI_01790 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
OLEDPIAI_01791 3e-30 thiS H thiamine diphosphate biosynthetic process
OLEDPIAI_01792 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
OLEDPIAI_01793 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OLEDPIAI_01794 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OLEDPIAI_01795 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OLEDPIAI_01796 5.9e-54 yjbX S Spore coat protein
OLEDPIAI_01797 5.2e-83 cotZ S Spore coat protein
OLEDPIAI_01798 3.4e-96 cotY S Spore coat protein Z
OLEDPIAI_01799 6.4e-77 cotX S Spore Coat Protein X and V domain
OLEDPIAI_01800 3e-32 cotW
OLEDPIAI_01801 2.3e-55 cotV S Spore Coat Protein X and V domain
OLEDPIAI_01802 8.7e-57 yjcA S Protein of unknown function (DUF1360)
OLEDPIAI_01805 2.9e-38 spoVIF S Stage VI sporulation protein F
OLEDPIAI_01806 0.0 yjcD 3.6.4.12 L DNA helicase
OLEDPIAI_01807 1.7e-38
OLEDPIAI_01808 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLEDPIAI_01809 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
OLEDPIAI_01810 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
OLEDPIAI_01811 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OLEDPIAI_01812 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OLEDPIAI_01813 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
OLEDPIAI_01814 1.1e-212 yjcL S Protein of unknown function (DUF819)
OLEDPIAI_01817 2.1e-190 S Putative amidase domain
OLEDPIAI_01818 2.6e-44 yjcN
OLEDPIAI_01821 8.5e-81 L Transposase
OLEDPIAI_01822 1.6e-72 yjcP
OLEDPIAI_01823 4.1e-49 S YjcQ protein
OLEDPIAI_01824 1.1e-92 yqaS L DNA packaging
OLEDPIAI_01825 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
OLEDPIAI_01826 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
OLEDPIAI_01828 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
OLEDPIAI_01829 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
OLEDPIAI_01830 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
OLEDPIAI_01831 4.8e-51 yjdF S Protein of unknown function (DUF2992)
OLEDPIAI_01832 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
OLEDPIAI_01834 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OLEDPIAI_01835 4.2e-29 S Domain of unknown function (DUF4177)
OLEDPIAI_01836 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
OLEDPIAI_01837 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OLEDPIAI_01839 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
OLEDPIAI_01840 5.5e-83 S Protein of unknown function (DUF2690)
OLEDPIAI_01841 3.6e-21 yjfB S Putative motility protein
OLEDPIAI_01842 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
OLEDPIAI_01843 1.2e-45 T PhoQ Sensor
OLEDPIAI_01844 8.9e-104 yjgB S Domain of unknown function (DUF4309)
OLEDPIAI_01845 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
OLEDPIAI_01846 4.3e-95 yjgD S Protein of unknown function (DUF1641)
OLEDPIAI_01847 8.7e-07 S Domain of unknown function (DUF4352)
OLEDPIAI_01848 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
OLEDPIAI_01850 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
OLEDPIAI_01851 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OLEDPIAI_01852 8.2e-30
OLEDPIAI_01853 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OLEDPIAI_01854 1.9e-122 ybbM S transport system, permease component
OLEDPIAI_01855 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
OLEDPIAI_01856 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
OLEDPIAI_01857 2.8e-93 yjlB S Cupin domain
OLEDPIAI_01858 7.1e-66 yjlC S Protein of unknown function (DUF1641)
OLEDPIAI_01859 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
OLEDPIAI_01860 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
OLEDPIAI_01861 5.8e-250 yjmB G symporter YjmB
OLEDPIAI_01862 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
OLEDPIAI_01863 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
OLEDPIAI_01864 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
OLEDPIAI_01865 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_01866 3.7e-227 exuT G Sugar (and other) transporter
OLEDPIAI_01867 2.3e-184 exuR K transcriptional
OLEDPIAI_01868 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
OLEDPIAI_01869 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
OLEDPIAI_01870 4.3e-130 MA20_18170 S membrane transporter protein
OLEDPIAI_01871 3.3e-80 yjoA S DinB family
OLEDPIAI_01872 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
OLEDPIAI_01873 2.1e-213 S response regulator aspartate phosphatase
OLEDPIAI_01875 6.3e-41 S YCII-related domain
OLEDPIAI_01876 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
OLEDPIAI_01877 2.1e-61 yjqA S Bacterial PH domain
OLEDPIAI_01878 4.2e-112 yjqB S Pfam:DUF867
OLEDPIAI_01879 4.4e-160 ydbD P Catalase
OLEDPIAI_01880 1.6e-111 xkdA E IrrE N-terminal-like domain
OLEDPIAI_01881 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
OLEDPIAI_01883 5.9e-157 xkdB K sequence-specific DNA binding
OLEDPIAI_01884 6.4e-119 xkdC L Bacterial dnaA protein
OLEDPIAI_01887 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
OLEDPIAI_01888 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OLEDPIAI_01889 4.8e-140 xtmA L phage terminase small subunit
OLEDPIAI_01890 9.6e-255 xtmB S phage terminase, large subunit
OLEDPIAI_01891 5.4e-286 yqbA S portal protein
OLEDPIAI_01892 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
OLEDPIAI_01893 5.8e-169 xkdG S Phage capsid family
OLEDPIAI_01894 5.5e-65 yqbG S Protein of unknown function (DUF3199)
OLEDPIAI_01895 7.3e-64 yqbH S Domain of unknown function (DUF3599)
OLEDPIAI_01896 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
OLEDPIAI_01897 1.9e-77 xkdJ
OLEDPIAI_01898 2.5e-256 xkdK S Phage tail sheath C-terminal domain
OLEDPIAI_01899 6.1e-76 xkdM S Phage tail tube protein
OLEDPIAI_01900 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
OLEDPIAI_01901 0.0 xkdO L Transglycosylase SLT domain
OLEDPIAI_01902 3.7e-122 xkdP S Lysin motif
OLEDPIAI_01903 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
OLEDPIAI_01904 2.1e-39 xkdR S Protein of unknown function (DUF2577)
OLEDPIAI_01905 9.6e-71 xkdS S Protein of unknown function (DUF2634)
OLEDPIAI_01906 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OLEDPIAI_01907 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OLEDPIAI_01908 6.7e-41
OLEDPIAI_01909 0.0
OLEDPIAI_01910 2.6e-55 xkdW S XkdW protein
OLEDPIAI_01911 1.7e-23 xkdX
OLEDPIAI_01912 1.2e-154 xepA
OLEDPIAI_01913 2.8e-39 xhlA S Haemolysin XhlA
OLEDPIAI_01914 9.3e-40 xhlB S SPP1 phage holin
OLEDPIAI_01915 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OLEDPIAI_01916 6.7e-23 spoIISB S Stage II sporulation protein SB
OLEDPIAI_01917 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
OLEDPIAI_01918 5.8e-175 pit P phosphate transporter
OLEDPIAI_01919 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
OLEDPIAI_01920 9.4e-242 steT E amino acid
OLEDPIAI_01921 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
OLEDPIAI_01923 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OLEDPIAI_01924 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OLEDPIAI_01926 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OLEDPIAI_01927 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
OLEDPIAI_01928 7.9e-154 dppA E D-aminopeptidase
OLEDPIAI_01929 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLEDPIAI_01930 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLEDPIAI_01931 3.4e-191 dppD P Belongs to the ABC transporter superfamily
OLEDPIAI_01932 0.0 dppE E ABC transporter substrate-binding protein
OLEDPIAI_01934 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OLEDPIAI_01935 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OLEDPIAI_01936 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OLEDPIAI_01937 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
OLEDPIAI_01938 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
OLEDPIAI_01939 5.3e-161 ykgA E Amidinotransferase
OLEDPIAI_01940 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
OLEDPIAI_01941 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OLEDPIAI_01942 1e-07
OLEDPIAI_01943 5.4e-130 ykjA S Protein of unknown function (DUF421)
OLEDPIAI_01944 1e-98 ykkA S Protein of unknown function (DUF664)
OLEDPIAI_01945 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OLEDPIAI_01946 3.5e-55 ykkC P Multidrug resistance protein
OLEDPIAI_01947 1.1e-50 ykkD P Multidrug resistance protein
OLEDPIAI_01948 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
OLEDPIAI_01949 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OLEDPIAI_01950 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OLEDPIAI_01951 1.3e-70 ohrA O Organic hydroperoxide resistance protein
OLEDPIAI_01952 3.9e-75 ohrR K COG1846 Transcriptional regulators
OLEDPIAI_01953 8.4e-72 ohrB O Organic hydroperoxide resistance protein
OLEDPIAI_01955 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
OLEDPIAI_01956 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OLEDPIAI_01957 1.7e-176 isp O Belongs to the peptidase S8 family
OLEDPIAI_01958 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OLEDPIAI_01959 1.8e-136 ykoC P Cobalt transport protein
OLEDPIAI_01960 4.6e-311 P ABC transporter, ATP-binding protein
OLEDPIAI_01961 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
OLEDPIAI_01962 7.9e-111 ykoF S YKOF-related Family
OLEDPIAI_01963 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_01964 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
OLEDPIAI_01965 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
OLEDPIAI_01966 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
OLEDPIAI_01969 2.2e-222 mgtE P Acts as a magnesium transporter
OLEDPIAI_01970 1.4e-53 tnrA K transcriptional
OLEDPIAI_01971 5.9e-18
OLEDPIAI_01972 6.9e-26 ykoL
OLEDPIAI_01973 1.3e-81 mhqR K transcriptional
OLEDPIAI_01974 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
OLEDPIAI_01975 3.7e-99 ykoP G polysaccharide deacetylase
OLEDPIAI_01976 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
OLEDPIAI_01977 0.0 ykoS
OLEDPIAI_01978 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OLEDPIAI_01979 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
OLEDPIAI_01980 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OLEDPIAI_01981 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
OLEDPIAI_01982 1.4e-116 ykoX S membrane-associated protein
OLEDPIAI_01983 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OLEDPIAI_01984 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLEDPIAI_01985 8.2e-117 rsgI S Anti-sigma factor N-terminus
OLEDPIAI_01986 1.9e-26 sspD S small acid-soluble spore protein
OLEDPIAI_01987 1.5e-124 ykrK S Domain of unknown function (DUF1836)
OLEDPIAI_01988 7e-156 htpX O Belongs to the peptidase M48B family
OLEDPIAI_01989 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
OLEDPIAI_01990 1.2e-10 ydfR S Protein of unknown function (DUF421)
OLEDPIAI_01991 4.5e-22 ykzE
OLEDPIAI_01992 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
OLEDPIAI_01993 0.0 kinE 2.7.13.3 T Histidine kinase
OLEDPIAI_01994 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OLEDPIAI_01996 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OLEDPIAI_01997 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OLEDPIAI_01998 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OLEDPIAI_01999 8e-232 mtnE 2.6.1.83 E Aminotransferase
OLEDPIAI_02000 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
OLEDPIAI_02001 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OLEDPIAI_02002 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
OLEDPIAI_02003 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OLEDPIAI_02004 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
OLEDPIAI_02005 6.4e-09 S Spo0E like sporulation regulatory protein
OLEDPIAI_02006 1.4e-64 eag
OLEDPIAI_02007 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
OLEDPIAI_02008 1.3e-75 ykvE K transcriptional
OLEDPIAI_02009 2.5e-125 motB N Flagellar motor protein
OLEDPIAI_02010 2.7e-138 motA N flagellar motor
OLEDPIAI_02011 0.0 clpE O Belongs to the ClpA ClpB family
OLEDPIAI_02012 8.7e-182 ykvI S membrane
OLEDPIAI_02013 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OLEDPIAI_02014 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
OLEDPIAI_02015 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OLEDPIAI_02016 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OLEDPIAI_02017 2e-61 ykvN K Transcriptional regulator
OLEDPIAI_02018 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
OLEDPIAI_02019 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
OLEDPIAI_02020 1.2e-35 3.5.1.104 M LysM domain
OLEDPIAI_02021 8.5e-133 G Glycosyl hydrolases family 18
OLEDPIAI_02022 5.6e-46 ykvR S Protein of unknown function (DUF3219)
OLEDPIAI_02023 6e-25 ykvS S protein conserved in bacteria
OLEDPIAI_02024 2.8e-28
OLEDPIAI_02025 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
OLEDPIAI_02026 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLEDPIAI_02027 4.9e-90 stoA CO thiol-disulfide
OLEDPIAI_02028 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OLEDPIAI_02029 3.8e-09
OLEDPIAI_02030 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OLEDPIAI_02032 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
OLEDPIAI_02034 4.5e-128 glcT K antiterminator
OLEDPIAI_02035 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLEDPIAI_02036 2.1e-39 ptsH G phosphocarrier protein HPr
OLEDPIAI_02037 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OLEDPIAI_02038 7.2e-39 splA S Transcriptional regulator
OLEDPIAI_02039 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
OLEDPIAI_02040 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLEDPIAI_02041 2e-264 mcpC NT chemotaxis protein
OLEDPIAI_02042 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OLEDPIAI_02043 8e-124 ykwD J protein with SCP PR1 domains
OLEDPIAI_02044 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
OLEDPIAI_02045 0.0 pilS 2.7.13.3 T Histidine kinase
OLEDPIAI_02046 8e-224 patA 2.6.1.1 E Aminotransferase
OLEDPIAI_02047 2.2e-15
OLEDPIAI_02048 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
OLEDPIAI_02049 1.7e-84 ykyB S YkyB-like protein
OLEDPIAI_02050 1.6e-238 ykuC EGP Major facilitator Superfamily
OLEDPIAI_02051 4.6e-88 ykuD S protein conserved in bacteria
OLEDPIAI_02052 9.4e-166 ykuE S Metallophosphoesterase
OLEDPIAI_02053 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLEDPIAI_02054 0.0 3.2.1.132 M Putative peptidoglycan binding domain
OLEDPIAI_02055 1.7e-93 M Peptidoglycan-binding domain 1 protein
OLEDPIAI_02057 5.2e-234 ykuI T Diguanylate phosphodiesterase
OLEDPIAI_02058 3.9e-37 ykuJ S protein conserved in bacteria
OLEDPIAI_02059 4.4e-94 ykuK S Ribonuclease H-like
OLEDPIAI_02060 3.9e-27 ykzF S Antirepressor AbbA
OLEDPIAI_02061 1.6e-76 ykuL S CBS domain
OLEDPIAI_02062 3.5e-168 ccpC K Transcriptional regulator
OLEDPIAI_02063 5.7e-88 fld C Flavodoxin domain
OLEDPIAI_02064 3.2e-177 ykuO
OLEDPIAI_02065 3.2e-80 fld C Flavodoxin
OLEDPIAI_02066 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OLEDPIAI_02067 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OLEDPIAI_02068 9e-37 ykuS S Belongs to the UPF0180 family
OLEDPIAI_02069 8.8e-142 ykuT M Mechanosensitive ion channel
OLEDPIAI_02070 3.9e-101 ykuU O Alkyl hydroperoxide reductase
OLEDPIAI_02071 4.4e-82 ykuV CO thiol-disulfide
OLEDPIAI_02072 5.8e-95 rok K Repressor of ComK
OLEDPIAI_02073 2.9e-147 yknT
OLEDPIAI_02074 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OLEDPIAI_02075 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OLEDPIAI_02076 8.1e-246 moeA 2.10.1.1 H molybdopterin
OLEDPIAI_02077 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
OLEDPIAI_02078 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
OLEDPIAI_02079 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OLEDPIAI_02080 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
OLEDPIAI_02081 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
OLEDPIAI_02082 1e-117 yknW S Yip1 domain
OLEDPIAI_02083 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OLEDPIAI_02084 2.5e-124 macB V ABC transporter, ATP-binding protein
OLEDPIAI_02085 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
OLEDPIAI_02086 3.1e-136 fruR K Transcriptional regulator
OLEDPIAI_02087 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
OLEDPIAI_02088 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OLEDPIAI_02089 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OLEDPIAI_02090 8.1e-39 ykoA
OLEDPIAI_02091 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OLEDPIAI_02092 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OLEDPIAI_02093 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OLEDPIAI_02094 1.1e-12 S Uncharacterized protein YkpC
OLEDPIAI_02095 7.7e-183 mreB D Rod-share determining protein MreBH
OLEDPIAI_02096 1.5e-43 abrB K of stationary sporulation gene expression
OLEDPIAI_02097 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
OLEDPIAI_02098 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
OLEDPIAI_02099 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
OLEDPIAI_02100 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OLEDPIAI_02101 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OLEDPIAI_02102 8.2e-31 ykzG S Belongs to the UPF0356 family
OLEDPIAI_02103 1.4e-147 ykrA S hydrolases of the HAD superfamily
OLEDPIAI_02104 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OLEDPIAI_02106 2e-115 recN L Putative cell-wall binding lipoprotein
OLEDPIAI_02107 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OLEDPIAI_02108 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OLEDPIAI_02109 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OLEDPIAI_02110 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OLEDPIAI_02111 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
OLEDPIAI_02112 3.5e-277 speA 4.1.1.19 E Arginine
OLEDPIAI_02113 1.6e-42 yktA S Belongs to the UPF0223 family
OLEDPIAI_02114 7.1e-118 yktB S Belongs to the UPF0637 family
OLEDPIAI_02115 7.1e-26 ykzI
OLEDPIAI_02116 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
OLEDPIAI_02117 6.9e-78 ykzC S Acetyltransferase (GNAT) family
OLEDPIAI_02118 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OLEDPIAI_02119 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
OLEDPIAI_02120 0.0 ylaA
OLEDPIAI_02121 2.7e-42 ylaB
OLEDPIAI_02122 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
OLEDPIAI_02123 1.2e-11 sigC S Putative zinc-finger
OLEDPIAI_02124 1.8e-38 ylaE
OLEDPIAI_02125 8.2e-22 S Family of unknown function (DUF5325)
OLEDPIAI_02126 0.0 typA T GTP-binding protein TypA
OLEDPIAI_02127 4.2e-47 ylaH S YlaH-like protein
OLEDPIAI_02128 2.5e-32 ylaI S protein conserved in bacteria
OLEDPIAI_02129 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OLEDPIAI_02130 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
OLEDPIAI_02131 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OLEDPIAI_02132 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
OLEDPIAI_02133 8.7e-44 ylaN S Belongs to the UPF0358 family
OLEDPIAI_02134 4.5e-214 ftsW D Belongs to the SEDS family
OLEDPIAI_02135 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OLEDPIAI_02136 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OLEDPIAI_02137 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OLEDPIAI_02138 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OLEDPIAI_02139 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OLEDPIAI_02140 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OLEDPIAI_02141 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OLEDPIAI_02142 3e-167 ctaG S cytochrome c oxidase
OLEDPIAI_02143 7e-62 ylbA S YugN-like family
OLEDPIAI_02144 2.6e-74 ylbB T COG0517 FOG CBS domain
OLEDPIAI_02145 3e-201 ylbC S protein with SCP PR1 domains
OLEDPIAI_02146 4.1e-63 ylbD S Putative coat protein
OLEDPIAI_02147 6.7e-37 ylbE S YlbE-like protein
OLEDPIAI_02148 1.8e-75 ylbF S Belongs to the UPF0342 family
OLEDPIAI_02149 7.5e-39 ylbG S UPF0298 protein
OLEDPIAI_02150 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
OLEDPIAI_02151 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OLEDPIAI_02152 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
OLEDPIAI_02153 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
OLEDPIAI_02154 6.8e-187 ylbL T Belongs to the peptidase S16 family
OLEDPIAI_02155 2.8e-235 ylbM S Belongs to the UPF0348 family
OLEDPIAI_02157 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
OLEDPIAI_02158 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OLEDPIAI_02159 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OLEDPIAI_02160 4e-89 ylbP K n-acetyltransferase
OLEDPIAI_02161 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OLEDPIAI_02162 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OLEDPIAI_02163 2.9e-78 mraZ K Belongs to the MraZ family
OLEDPIAI_02164 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OLEDPIAI_02165 3.7e-44 ftsL D Essential cell division protein
OLEDPIAI_02166 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OLEDPIAI_02167 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
OLEDPIAI_02168 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OLEDPIAI_02169 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OLEDPIAI_02170 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OLEDPIAI_02171 5.7e-186 spoVE D Belongs to the SEDS family
OLEDPIAI_02172 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OLEDPIAI_02173 5.3e-167 murB 1.3.1.98 M cell wall formation
OLEDPIAI_02174 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OLEDPIAI_02175 2.4e-103 ylxW S protein conserved in bacteria
OLEDPIAI_02176 1e-102 ylxX S protein conserved in bacteria
OLEDPIAI_02177 6.2e-58 sbp S small basic protein
OLEDPIAI_02178 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OLEDPIAI_02179 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OLEDPIAI_02180 0.0 bpr O COG1404 Subtilisin-like serine proteases
OLEDPIAI_02181 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OLEDPIAI_02182 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLEDPIAI_02183 6.2e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLEDPIAI_02184 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OLEDPIAI_02185 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
OLEDPIAI_02186 2.4e-37 ylmC S sporulation protein
OLEDPIAI_02187 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
OLEDPIAI_02188 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OLEDPIAI_02189 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OLEDPIAI_02190 1.3e-39 yggT S membrane
OLEDPIAI_02191 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
OLEDPIAI_02192 2.6e-67 divIVA D Cell division initiation protein
OLEDPIAI_02193 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OLEDPIAI_02194 1.3e-63 dksA T COG1734 DnaK suppressor protein
OLEDPIAI_02195 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OLEDPIAI_02196 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OLEDPIAI_02197 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OLEDPIAI_02198 9e-232 pyrP F Xanthine uracil
OLEDPIAI_02199 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OLEDPIAI_02200 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OLEDPIAI_02201 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OLEDPIAI_02202 0.0 carB 6.3.5.5 F Belongs to the CarB family
OLEDPIAI_02203 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OLEDPIAI_02204 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OLEDPIAI_02205 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OLEDPIAI_02206 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OLEDPIAI_02208 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OLEDPIAI_02209 1.1e-179 cysP P phosphate transporter
OLEDPIAI_02210 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OLEDPIAI_02211 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
OLEDPIAI_02212 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OLEDPIAI_02213 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
OLEDPIAI_02214 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
OLEDPIAI_02215 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OLEDPIAI_02216 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
OLEDPIAI_02217 2.4e-156 yloC S stress-induced protein
OLEDPIAI_02218 1.5e-40 ylzA S Belongs to the UPF0296 family
OLEDPIAI_02219 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OLEDPIAI_02220 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OLEDPIAI_02221 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OLEDPIAI_02222 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OLEDPIAI_02223 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OLEDPIAI_02224 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OLEDPIAI_02225 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OLEDPIAI_02226 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OLEDPIAI_02227 2.4e-141 stp 3.1.3.16 T phosphatase
OLEDPIAI_02228 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OLEDPIAI_02229 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OLEDPIAI_02230 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OLEDPIAI_02231 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
OLEDPIAI_02232 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OLEDPIAI_02233 5.5e-59 asp S protein conserved in bacteria
OLEDPIAI_02234 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
OLEDPIAI_02235 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
OLEDPIAI_02236 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
OLEDPIAI_02237 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OLEDPIAI_02238 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OLEDPIAI_02239 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OLEDPIAI_02240 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OLEDPIAI_02241 6.1e-129 IQ reductase
OLEDPIAI_02242 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OLEDPIAI_02243 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OLEDPIAI_02244 0.0 smc D Required for chromosome condensation and partitioning
OLEDPIAI_02245 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OLEDPIAI_02246 2.9e-87
OLEDPIAI_02247 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OLEDPIAI_02248 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OLEDPIAI_02249 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OLEDPIAI_02250 1.2e-36 ylqC S Belongs to the UPF0109 family
OLEDPIAI_02251 1.3e-61 ylqD S YlqD protein
OLEDPIAI_02252 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OLEDPIAI_02253 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OLEDPIAI_02254 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OLEDPIAI_02255 9.3e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OLEDPIAI_02256 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OLEDPIAI_02257 8.5e-291 ylqG
OLEDPIAI_02258 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
OLEDPIAI_02259 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OLEDPIAI_02260 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OLEDPIAI_02261 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
OLEDPIAI_02262 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OLEDPIAI_02263 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OLEDPIAI_02264 2.5e-169 xerC L tyrosine recombinase XerC
OLEDPIAI_02265 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OLEDPIAI_02266 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OLEDPIAI_02267 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OLEDPIAI_02268 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OLEDPIAI_02269 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
OLEDPIAI_02270 1.9e-31 fliE N Flagellar hook-basal body
OLEDPIAI_02271 2.4e-255 fliF N The M ring may be actively involved in energy transduction
OLEDPIAI_02272 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OLEDPIAI_02273 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
OLEDPIAI_02274 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OLEDPIAI_02275 1.5e-69 fliJ N Flagellar biosynthesis chaperone
OLEDPIAI_02276 7.7e-37 ylxF S MgtE intracellular N domain
OLEDPIAI_02277 1.2e-221 fliK N Flagellar hook-length control protein
OLEDPIAI_02278 1.7e-72 flgD N Flagellar basal body rod modification protein
OLEDPIAI_02279 8.2e-140 flgG N Flagellar basal body rod
OLEDPIAI_02280 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
OLEDPIAI_02281 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OLEDPIAI_02282 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OLEDPIAI_02283 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
OLEDPIAI_02284 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
OLEDPIAI_02285 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
OLEDPIAI_02286 2.2e-36 fliQ N Role in flagellar biosynthesis
OLEDPIAI_02287 3.6e-132 fliR N Flagellar biosynthetic protein FliR
OLEDPIAI_02288 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OLEDPIAI_02289 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OLEDPIAI_02290 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
OLEDPIAI_02291 7.5e-158 flhG D Belongs to the ParA family
OLEDPIAI_02292 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OLEDPIAI_02293 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
OLEDPIAI_02294 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
OLEDPIAI_02295 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OLEDPIAI_02296 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OLEDPIAI_02297 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLEDPIAI_02298 4.3e-78 ylxL
OLEDPIAI_02299 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
OLEDPIAI_02300 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OLEDPIAI_02301 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OLEDPIAI_02302 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OLEDPIAI_02303 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OLEDPIAI_02304 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
OLEDPIAI_02305 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OLEDPIAI_02306 7.7e-233 rasP M zinc metalloprotease
OLEDPIAI_02307 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OLEDPIAI_02308 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OLEDPIAI_02309 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
OLEDPIAI_02310 1.1e-203 nusA K Participates in both transcription termination and antitermination
OLEDPIAI_02311 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
OLEDPIAI_02312 3.1e-47 ylxQ J ribosomal protein
OLEDPIAI_02313 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OLEDPIAI_02314 3e-44 ylxP S protein conserved in bacteria
OLEDPIAI_02315 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OLEDPIAI_02316 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OLEDPIAI_02317 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OLEDPIAI_02318 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OLEDPIAI_02319 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OLEDPIAI_02320 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
OLEDPIAI_02321 4.4e-233 pepR S Belongs to the peptidase M16 family
OLEDPIAI_02322 2.6e-42 ymxH S YlmC YmxH family
OLEDPIAI_02323 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
OLEDPIAI_02324 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OLEDPIAI_02325 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OLEDPIAI_02326 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OLEDPIAI_02327 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OLEDPIAI_02328 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OLEDPIAI_02329 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
OLEDPIAI_02330 4.4e-32 S YlzJ-like protein
OLEDPIAI_02331 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OLEDPIAI_02332 1.4e-133 ymfC K Transcriptional regulator
OLEDPIAI_02333 1.5e-206 ymfD EGP Major facilitator Superfamily
OLEDPIAI_02334 2.9e-235 ymfF S Peptidase M16
OLEDPIAI_02335 1.4e-242 ymfH S zinc protease
OLEDPIAI_02336 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OLEDPIAI_02337 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
OLEDPIAI_02338 2.7e-143 ymfK S Protein of unknown function (DUF3388)
OLEDPIAI_02339 1.9e-124 ymfM S protein conserved in bacteria
OLEDPIAI_02340 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OLEDPIAI_02341 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
OLEDPIAI_02342 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OLEDPIAI_02343 1e-215 pbpX V Beta-lactamase
OLEDPIAI_02344 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
OLEDPIAI_02345 1.9e-152 ymdB S protein conserved in bacteria
OLEDPIAI_02346 1.2e-36 spoVS S Stage V sporulation protein S
OLEDPIAI_02347 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
OLEDPIAI_02348 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OLEDPIAI_02349 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OLEDPIAI_02350 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OLEDPIAI_02351 2.2e-88 cotE S Spore coat protein
OLEDPIAI_02352 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OLEDPIAI_02353 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OLEDPIAI_02354 2.3e-70 S Regulatory protein YrvL
OLEDPIAI_02356 1.2e-97 ymcC S Membrane
OLEDPIAI_02357 4.4e-109 pksA K Transcriptional regulator
OLEDPIAI_02358 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
OLEDPIAI_02359 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OLEDPIAI_02361 2.4e-186 pksD Q Acyl transferase domain
OLEDPIAI_02362 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OLEDPIAI_02363 1.4e-37 acpK IQ Phosphopantetheine attachment site
OLEDPIAI_02364 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OLEDPIAI_02365 1.3e-245 pksG 2.3.3.10 I synthase
OLEDPIAI_02366 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
OLEDPIAI_02367 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
OLEDPIAI_02368 0.0 rhiB IQ polyketide synthase
OLEDPIAI_02369 0.0 pfaA Q Polyketide synthase of type I
OLEDPIAI_02370 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
OLEDPIAI_02371 0.0 dhbF IQ polyketide synthase
OLEDPIAI_02372 0.0 pks13 HQ Beta-ketoacyl synthase
OLEDPIAI_02373 2.5e-233 cypA C Cytochrome P450
OLEDPIAI_02374 1.2e-61 ymzB
OLEDPIAI_02375 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
OLEDPIAI_02376 4.6e-252 aprX O Belongs to the peptidase S8 family
OLEDPIAI_02377 2.1e-126 ymaC S Replication protein
OLEDPIAI_02378 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
OLEDPIAI_02379 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
OLEDPIAI_02380 4.9e-51 ebrA P Small Multidrug Resistance protein
OLEDPIAI_02382 2.1e-46 ymaF S YmaF family
OLEDPIAI_02383 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OLEDPIAI_02384 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OLEDPIAI_02385 6.3e-23
OLEDPIAI_02386 4.5e-22 ymzA
OLEDPIAI_02387 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OLEDPIAI_02388 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLEDPIAI_02389 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLEDPIAI_02390 2e-109 ymaB
OLEDPIAI_02391 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OLEDPIAI_02392 1.7e-176 spoVK O stage V sporulation protein K
OLEDPIAI_02393 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OLEDPIAI_02394 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OLEDPIAI_02395 1.1e-68 glnR K transcriptional
OLEDPIAI_02396 7e-261 glnA 6.3.1.2 E glutamine synthetase
OLEDPIAI_02397 5e-10
OLEDPIAI_02398 2.5e-32
OLEDPIAI_02399 5.8e-39
OLEDPIAI_02400 6.8e-80 G regulation of fungal-type cell wall biogenesis
OLEDPIAI_02401 4.9e-145 ynaC
OLEDPIAI_02402 2e-99 ynaD J Acetyltransferase (GNAT) domain
OLEDPIAI_02403 1.9e-123 ynaE S Domain of unknown function (DUF3885)
OLEDPIAI_02404 6.4e-60 ynaF
OLEDPIAI_02407 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
OLEDPIAI_02408 2.7e-255 xynT G MFS/sugar transport protein
OLEDPIAI_02409 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OLEDPIAI_02410 1e-215 xylR GK ROK family
OLEDPIAI_02411 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
OLEDPIAI_02412 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
OLEDPIAI_02413 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
OLEDPIAI_02414 3.5e-247 iolT EGP Major facilitator Superfamily
OLEDPIAI_02415 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OLEDPIAI_02416 6.3e-84 yncE S Protein of unknown function (DUF2691)
OLEDPIAI_02417 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OLEDPIAI_02418 5.2e-15
OLEDPIAI_02421 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OLEDPIAI_02423 1.3e-134 S Domain of unknown function, YrpD
OLEDPIAI_02426 7.9e-25 tatA U protein secretion
OLEDPIAI_02427 1.8e-71
OLEDPIAI_02428 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
OLEDPIAI_02431 5.7e-286 gerAA EG Spore germination protein
OLEDPIAI_02432 4.5e-197 gerAB U Spore germination
OLEDPIAI_02433 4.2e-220 gerLC S Spore germination protein
OLEDPIAI_02434 7.7e-154 yndG S DoxX-like family
OLEDPIAI_02435 2.6e-117 yndH S Domain of unknown function (DUF4166)
OLEDPIAI_02436 0.0 yndJ S YndJ-like protein
OLEDPIAI_02438 8.6e-139 yndL S Replication protein
OLEDPIAI_02439 5.8e-74 yndM S Protein of unknown function (DUF2512)
OLEDPIAI_02440 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
OLEDPIAI_02442 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OLEDPIAI_02443 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OLEDPIAI_02444 9.2e-113 yneB L resolvase
OLEDPIAI_02445 1.3e-32 ynzC S UPF0291 protein
OLEDPIAI_02446 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OLEDPIAI_02447 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
OLEDPIAI_02448 1.8e-28 yneF S UPF0154 protein
OLEDPIAI_02449 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
OLEDPIAI_02450 7.1e-127 ccdA O cytochrome c biogenesis protein
OLEDPIAI_02451 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
OLEDPIAI_02452 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
OLEDPIAI_02453 4.2e-74 yneK S Protein of unknown function (DUF2621)
OLEDPIAI_02454 4.1e-65 hspX O Spore coat protein
OLEDPIAI_02455 3.9e-19 sspP S Belongs to the SspP family
OLEDPIAI_02456 2.2e-14 sspO S Belongs to the SspO family
OLEDPIAI_02457 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OLEDPIAI_02458 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OLEDPIAI_02460 3.1e-08 sspN S Small acid-soluble spore protein N family
OLEDPIAI_02461 3.9e-35 tlp S Belongs to the Tlp family
OLEDPIAI_02462 1.2e-73 yneP S Thioesterase-like superfamily
OLEDPIAI_02463 1.3e-53 yneQ
OLEDPIAI_02464 4.1e-49 yneR S Belongs to the HesB IscA family
OLEDPIAI_02465 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OLEDPIAI_02466 6.6e-69 yccU S CoA-binding protein
OLEDPIAI_02467 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OLEDPIAI_02468 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OLEDPIAI_02469 2.3e-12
OLEDPIAI_02470 1.3e-57 ynfC
OLEDPIAI_02471 8.2e-252 agcS E Sodium alanine symporter
OLEDPIAI_02472 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
OLEDPIAI_02474 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
OLEDPIAI_02475 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
OLEDPIAI_02476 2.4e-80 yngA S membrane
OLEDPIAI_02477 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OLEDPIAI_02478 5.5e-104 yngC S membrane-associated protein
OLEDPIAI_02479 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
OLEDPIAI_02480 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OLEDPIAI_02481 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OLEDPIAI_02482 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
OLEDPIAI_02483 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
OLEDPIAI_02484 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
OLEDPIAI_02485 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OLEDPIAI_02486 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
OLEDPIAI_02487 1.8e-31 S Family of unknown function (DUF5367)
OLEDPIAI_02488 1.3e-306 yngK T Glycosyl hydrolase-like 10
OLEDPIAI_02489 2.8e-64 yngL S Protein of unknown function (DUF1360)
OLEDPIAI_02490 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
OLEDPIAI_02491 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLEDPIAI_02493 9.3e-116
OLEDPIAI_02494 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OLEDPIAI_02495 6.2e-145 S Phage tail protein
OLEDPIAI_02496 0.0 S Pfam Transposase IS66
OLEDPIAI_02497 6.4e-115
OLEDPIAI_02498 0.0 G Exopolysaccharide biosynthesis protein
OLEDPIAI_02499 6.5e-164
OLEDPIAI_02501 1.6e-186 3.5.1.28 M Ami_2
OLEDPIAI_02502 4.4e-32 bhlA S BhlA holin family
OLEDPIAI_02503 5.5e-40 S SPP1 phage holin
OLEDPIAI_02504 3.4e-74 O protein disulfide oxidoreductase activity
OLEDPIAI_02505 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OLEDPIAI_02506 1.2e-70 CO cell redox homeostasis
OLEDPIAI_02507 0.0 V Peptidase C39 family
OLEDPIAI_02510 1.9e-239 S impB/mucB/samB family C-terminal domain
OLEDPIAI_02511 5.8e-55 S YolD-like protein
OLEDPIAI_02512 2.5e-42
OLEDPIAI_02514 6.8e-09 S Domain of unknown function (DUF4879)
OLEDPIAI_02516 2.8e-99 J Acetyltransferase (GNAT) domain
OLEDPIAI_02517 3.2e-109 yokK S SMI1 / KNR4 family
OLEDPIAI_02518 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
OLEDPIAI_02519 1.2e-302 UW nuclease activity
OLEDPIAI_02520 6.7e-92 yokH G SMI1 / KNR4 family
OLEDPIAI_02521 4.1e-203
OLEDPIAI_02522 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
OLEDPIAI_02523 1.1e-83 S Bacterial PH domain
OLEDPIAI_02524 8.4e-156 aacC 2.3.1.81 V aminoglycoside
OLEDPIAI_02527 8.9e-95
OLEDPIAI_02528 1.6e-107
OLEDPIAI_02529 2.7e-307 yokA L Recombinase
OLEDPIAI_02530 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
OLEDPIAI_02531 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OLEDPIAI_02532 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OLEDPIAI_02533 1.6e-70 ypoP K transcriptional
OLEDPIAI_02534 2.6e-223 mepA V MATE efflux family protein
OLEDPIAI_02535 5.5e-29 ypmT S Uncharacterized ympT
OLEDPIAI_02536 5e-99 ypmS S protein conserved in bacteria
OLEDPIAI_02537 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
OLEDPIAI_02538 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OLEDPIAI_02539 3.1e-40 ypmP S Protein of unknown function (DUF2535)
OLEDPIAI_02540 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OLEDPIAI_02541 1.6e-185 pspF K Transcriptional regulator
OLEDPIAI_02542 4.2e-110 hlyIII S protein, Hemolysin III
OLEDPIAI_02543 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OLEDPIAI_02544 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OLEDPIAI_02545 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OLEDPIAI_02546 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OLEDPIAI_02547 7.8e-114 ypjP S YpjP-like protein
OLEDPIAI_02548 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
OLEDPIAI_02549 1.7e-75 yphP S Belongs to the UPF0403 family
OLEDPIAI_02550 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OLEDPIAI_02551 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
OLEDPIAI_02552 3.1e-110 ypgQ S phosphohydrolase
OLEDPIAI_02553 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OLEDPIAI_02554 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OLEDPIAI_02555 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
OLEDPIAI_02556 7.9e-31 cspD K Cold-shock protein
OLEDPIAI_02557 3.8e-16 degR
OLEDPIAI_02558 8.1e-31 S Protein of unknown function (DUF2564)
OLEDPIAI_02559 2.6e-27 ypeQ S Zinc-finger
OLEDPIAI_02560 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
OLEDPIAI_02561 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OLEDPIAI_02562 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
OLEDPIAI_02564 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
OLEDPIAI_02565 2e-07
OLEDPIAI_02566 1e-38 ypbS S Protein of unknown function (DUF2533)
OLEDPIAI_02567 0.0 ypbR S Dynamin family
OLEDPIAI_02568 5.1e-87 ypbQ S protein conserved in bacteria
OLEDPIAI_02569 4.4e-208 bcsA Q Naringenin-chalcone synthase
OLEDPIAI_02570 1.6e-228 pbuX F xanthine
OLEDPIAI_02571 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OLEDPIAI_02572 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OLEDPIAI_02573 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
OLEDPIAI_02574 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
OLEDPIAI_02575 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
OLEDPIAI_02576 3.9e-187 ptxS K transcriptional
OLEDPIAI_02577 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OLEDPIAI_02578 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLEDPIAI_02579 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
OLEDPIAI_02581 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OLEDPIAI_02582 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OLEDPIAI_02583 3.3e-92 ypsA S Belongs to the UPF0398 family
OLEDPIAI_02584 1.3e-237 yprB L RNase_H superfamily
OLEDPIAI_02585 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OLEDPIAI_02586 7.2e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OLEDPIAI_02587 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
OLEDPIAI_02588 1.2e-48 yppG S YppG-like protein
OLEDPIAI_02590 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
OLEDPIAI_02593 2.6e-188 yppC S Protein of unknown function (DUF2515)
OLEDPIAI_02594 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OLEDPIAI_02595 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
OLEDPIAI_02596 4.7e-93 ypoC
OLEDPIAI_02597 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OLEDPIAI_02598 5.7e-129 dnaD L DNA replication protein DnaD
OLEDPIAI_02599 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
OLEDPIAI_02600 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OLEDPIAI_02601 3.4e-80 ypmB S protein conserved in bacteria
OLEDPIAI_02602 6.7e-23 ypmA S Protein of unknown function (DUF4264)
OLEDPIAI_02603 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OLEDPIAI_02604 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OLEDPIAI_02605 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OLEDPIAI_02606 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OLEDPIAI_02607 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OLEDPIAI_02608 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OLEDPIAI_02609 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
OLEDPIAI_02610 6.9e-130 bshB1 S proteins, LmbE homologs
OLEDPIAI_02611 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
OLEDPIAI_02612 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OLEDPIAI_02613 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
OLEDPIAI_02614 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
OLEDPIAI_02615 6.1e-143 ypjB S sporulation protein
OLEDPIAI_02616 4.4e-98 ypjA S membrane
OLEDPIAI_02617 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
OLEDPIAI_02618 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
OLEDPIAI_02619 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
OLEDPIAI_02620 8.5e-78 ypiF S Protein of unknown function (DUF2487)
OLEDPIAI_02621 2.8e-99 ypiB S Belongs to the UPF0302 family
OLEDPIAI_02622 4.1e-234 S COG0457 FOG TPR repeat
OLEDPIAI_02623 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OLEDPIAI_02624 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OLEDPIAI_02625 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OLEDPIAI_02626 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OLEDPIAI_02627 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OLEDPIAI_02628 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
OLEDPIAI_02629 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
OLEDPIAI_02630 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OLEDPIAI_02631 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OLEDPIAI_02632 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OLEDPIAI_02633 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OLEDPIAI_02634 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OLEDPIAI_02635 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
OLEDPIAI_02636 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OLEDPIAI_02637 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OLEDPIAI_02638 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OLEDPIAI_02639 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OLEDPIAI_02640 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OLEDPIAI_02641 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
OLEDPIAI_02642 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OLEDPIAI_02643 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OLEDPIAI_02644 5.4e-138 yphF
OLEDPIAI_02645 1.6e-18 yphE S Protein of unknown function (DUF2768)
OLEDPIAI_02646 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OLEDPIAI_02647 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OLEDPIAI_02648 1.6e-28 ypzH
OLEDPIAI_02649 2.5e-161 seaA S YIEGIA protein
OLEDPIAI_02650 1.3e-102 yphA
OLEDPIAI_02651 1e-07 S YpzI-like protein
OLEDPIAI_02652 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OLEDPIAI_02653 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
OLEDPIAI_02654 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OLEDPIAI_02655 1.8e-23 S Family of unknown function (DUF5359)
OLEDPIAI_02656 9.2e-113 ypfA M Flagellar protein YcgR
OLEDPIAI_02657 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
OLEDPIAI_02658 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
OLEDPIAI_02659 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
OLEDPIAI_02660 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
OLEDPIAI_02661 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OLEDPIAI_02662 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OLEDPIAI_02663 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
OLEDPIAI_02664 2.8e-81 ypbF S Protein of unknown function (DUF2663)
OLEDPIAI_02665 4.6e-81 ypbE M Lysin motif
OLEDPIAI_02666 2.2e-100 ypbD S metal-dependent membrane protease
OLEDPIAI_02667 3.2e-286 recQ 3.6.4.12 L DNA helicase
OLEDPIAI_02668 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
OLEDPIAI_02669 4.7e-41 fer C Ferredoxin
OLEDPIAI_02670 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OLEDPIAI_02671 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OLEDPIAI_02672 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OLEDPIAI_02673 6.8e-201 rsiX
OLEDPIAI_02674 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
OLEDPIAI_02675 0.0 resE 2.7.13.3 T Histidine kinase
OLEDPIAI_02676 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_02677 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OLEDPIAI_02678 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OLEDPIAI_02679 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OLEDPIAI_02680 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OLEDPIAI_02681 1.9e-87 spmB S Spore maturation protein
OLEDPIAI_02682 3.5e-103 spmA S Spore maturation protein
OLEDPIAI_02683 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
OLEDPIAI_02684 4e-98 ypuI S Protein of unknown function (DUF3907)
OLEDPIAI_02685 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OLEDPIAI_02686 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OLEDPIAI_02687 4.5e-94 ypuF S Domain of unknown function (DUF309)
OLEDPIAI_02688 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLEDPIAI_02689 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OLEDPIAI_02690 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OLEDPIAI_02691 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
OLEDPIAI_02692 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OLEDPIAI_02693 6e-55 ypuD
OLEDPIAI_02694 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OLEDPIAI_02695 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
OLEDPIAI_02696 1.5e-17 S SNARE associated Golgi protein
OLEDPIAI_02699 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OLEDPIAI_02700 1.6e-149 ypuA S Secreted protein
OLEDPIAI_02701 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OLEDPIAI_02702 1.4e-273 spoVAF EG Stage V sporulation protein AF
OLEDPIAI_02703 1.4e-110 spoVAEA S stage V sporulation protein
OLEDPIAI_02704 2.2e-57 spoVAEB S stage V sporulation protein
OLEDPIAI_02705 9e-192 spoVAD I Stage V sporulation protein AD
OLEDPIAI_02706 2.3e-78 spoVAC S stage V sporulation protein AC
OLEDPIAI_02707 1e-67 spoVAB S Stage V sporulation protein AB
OLEDPIAI_02708 7.4e-112 spoVAA S Stage V sporulation protein AA
OLEDPIAI_02709 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLEDPIAI_02710 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OLEDPIAI_02711 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
OLEDPIAI_02712 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
OLEDPIAI_02713 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OLEDPIAI_02714 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OLEDPIAI_02715 2.6e-166 xerD L recombinase XerD
OLEDPIAI_02716 3.7e-37 S Protein of unknown function (DUF4227)
OLEDPIAI_02717 2.4e-80 fur P Belongs to the Fur family
OLEDPIAI_02718 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OLEDPIAI_02719 2e-32 yqkK
OLEDPIAI_02720 5.5e-242 mleA 1.1.1.38 C malic enzyme
OLEDPIAI_02721 3.1e-235 mleN C Na H antiporter
OLEDPIAI_02722 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
OLEDPIAI_02723 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
OLEDPIAI_02724 4.5e-58 ansR K Transcriptional regulator
OLEDPIAI_02725 3e-223 yqxK 3.6.4.12 L DNA helicase
OLEDPIAI_02726 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
OLEDPIAI_02728 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
OLEDPIAI_02729 4e-14 yqkE S Protein of unknown function (DUF3886)
OLEDPIAI_02730 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
OLEDPIAI_02731 9.4e-39 yqkC S Protein of unknown function (DUF2552)
OLEDPIAI_02732 2.8e-54 yqkB S Belongs to the HesB IscA family
OLEDPIAI_02733 4.7e-196 yqkA K GrpB protein
OLEDPIAI_02734 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
OLEDPIAI_02735 3.6e-87 yqjY K acetyltransferase
OLEDPIAI_02736 2.2e-49 S YolD-like protein
OLEDPIAI_02737 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OLEDPIAI_02739 5.2e-226 yqjV G Major Facilitator Superfamily
OLEDPIAI_02741 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLEDPIAI_02742 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
OLEDPIAI_02743 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
OLEDPIAI_02744 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_02745 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
OLEDPIAI_02746 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OLEDPIAI_02747 0.0 rocB E arginine degradation protein
OLEDPIAI_02748 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OLEDPIAI_02749 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OLEDPIAI_02750 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OLEDPIAI_02751 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OLEDPIAI_02752 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OLEDPIAI_02753 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OLEDPIAI_02754 4.5e-24 yqzJ
OLEDPIAI_02755 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OLEDPIAI_02756 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
OLEDPIAI_02757 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
OLEDPIAI_02758 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OLEDPIAI_02759 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
OLEDPIAI_02761 1.4e-98 yqjB S protein conserved in bacteria
OLEDPIAI_02762 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
OLEDPIAI_02763 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OLEDPIAI_02764 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
OLEDPIAI_02765 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
OLEDPIAI_02766 9.3e-77 yqiW S Belongs to the UPF0403 family
OLEDPIAI_02767 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OLEDPIAI_02768 7.9e-208 norA EGP Major facilitator Superfamily
OLEDPIAI_02769 2.6e-152 bmrR K helix_turn_helix, mercury resistance
OLEDPIAI_02770 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OLEDPIAI_02771 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OLEDPIAI_02772 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OLEDPIAI_02773 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OLEDPIAI_02774 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
OLEDPIAI_02775 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
OLEDPIAI_02776 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
OLEDPIAI_02777 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
OLEDPIAI_02778 4e-34 yqzF S Protein of unknown function (DUF2627)
OLEDPIAI_02779 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OLEDPIAI_02780 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
OLEDPIAI_02781 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
OLEDPIAI_02782 1.8e-212 mmgC I acyl-CoA dehydrogenase
OLEDPIAI_02783 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
OLEDPIAI_02784 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
OLEDPIAI_02785 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OLEDPIAI_02786 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
OLEDPIAI_02787 5.9e-27
OLEDPIAI_02788 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OLEDPIAI_02790 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OLEDPIAI_02791 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
OLEDPIAI_02792 0.0 recN L May be involved in recombinational repair of damaged DNA
OLEDPIAI_02793 1.7e-78 argR K Regulates arginine biosynthesis genes
OLEDPIAI_02794 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
OLEDPIAI_02795 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OLEDPIAI_02796 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OLEDPIAI_02797 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OLEDPIAI_02798 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OLEDPIAI_02799 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OLEDPIAI_02800 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OLEDPIAI_02801 2.1e-67 yqhY S protein conserved in bacteria
OLEDPIAI_02802 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OLEDPIAI_02803 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OLEDPIAI_02804 9.9e-91 spoIIIAH S SpoIIIAH-like protein
OLEDPIAI_02805 6.9e-103 spoIIIAG S stage III sporulation protein AG
OLEDPIAI_02806 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
OLEDPIAI_02807 1.3e-197 spoIIIAE S stage III sporulation protein AE
OLEDPIAI_02808 2.3e-58 spoIIIAD S Stage III sporulation protein AD
OLEDPIAI_02809 7.6e-29 spoIIIAC S stage III sporulation protein AC
OLEDPIAI_02810 2.9e-85 spoIIIAB S Stage III sporulation protein
OLEDPIAI_02811 1.2e-171 spoIIIAA S stage III sporulation protein AA
OLEDPIAI_02812 7.9e-37 yqhV S Protein of unknown function (DUF2619)
OLEDPIAI_02813 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OLEDPIAI_02814 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OLEDPIAI_02815 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
OLEDPIAI_02816 2.3e-93 yqhR S Conserved membrane protein YqhR
OLEDPIAI_02817 2.1e-174 yqhQ S Protein of unknown function (DUF1385)
OLEDPIAI_02818 2.2e-61 yqhP
OLEDPIAI_02819 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
OLEDPIAI_02820 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OLEDPIAI_02821 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OLEDPIAI_02822 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
OLEDPIAI_02823 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OLEDPIAI_02824 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OLEDPIAI_02825 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
OLEDPIAI_02826 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OLEDPIAI_02827 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
OLEDPIAI_02828 1.2e-24 sinI S Anti-repressor SinI
OLEDPIAI_02829 1e-54 sinR K transcriptional
OLEDPIAI_02830 2.3e-142 tasA S Cell division protein FtsN
OLEDPIAI_02831 6.7e-59 sipW 3.4.21.89 U Signal peptidase
OLEDPIAI_02832 2.1e-116 yqxM
OLEDPIAI_02833 7.3e-54 yqzG S Protein of unknown function (DUF3889)
OLEDPIAI_02834 1.4e-26 yqzE S YqzE-like protein
OLEDPIAI_02835 3.7e-42 S ComG operon protein 7
OLEDPIAI_02836 5.5e-49 comGF U Putative Competence protein ComGF
OLEDPIAI_02837 1.1e-59 comGE
OLEDPIAI_02838 4.4e-71 gspH NU protein transport across the cell outer membrane
OLEDPIAI_02839 1.4e-47 comGC U Required for transformation and DNA binding
OLEDPIAI_02840 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
OLEDPIAI_02841 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OLEDPIAI_02843 7.2e-175 corA P Mg2 transporter protein
OLEDPIAI_02844 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OLEDPIAI_02845 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OLEDPIAI_02847 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
OLEDPIAI_02848 1.8e-37 yqgY S Protein of unknown function (DUF2626)
OLEDPIAI_02849 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OLEDPIAI_02850 8.9e-23 yqgW S Protein of unknown function (DUF2759)
OLEDPIAI_02851 6.9e-50 yqgV S Thiamine-binding protein
OLEDPIAI_02852 2.7e-199 yqgU
OLEDPIAI_02853 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
OLEDPIAI_02854 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OLEDPIAI_02855 5.2e-181 glcK 2.7.1.2 G Glucokinase
OLEDPIAI_02856 3.1e-33 yqgQ S Protein conserved in bacteria
OLEDPIAI_02857 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
OLEDPIAI_02858 2.5e-09 yqgO
OLEDPIAI_02859 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OLEDPIAI_02860 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OLEDPIAI_02861 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
OLEDPIAI_02863 9.2e-51 yqzD
OLEDPIAI_02864 1.9e-75 yqzC S YceG-like family
OLEDPIAI_02865 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OLEDPIAI_02866 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OLEDPIAI_02867 4.4e-158 pstA P Phosphate transport system permease
OLEDPIAI_02868 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
OLEDPIAI_02869 5.3e-151 pstS P Phosphate
OLEDPIAI_02870 0.0 pbpA 3.4.16.4 M penicillin-binding protein
OLEDPIAI_02871 2.5e-231 yqgE EGP Major facilitator superfamily
OLEDPIAI_02872 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
OLEDPIAI_02873 4e-73 yqgC S protein conserved in bacteria
OLEDPIAI_02874 8.5e-134 yqgB S Protein of unknown function (DUF1189)
OLEDPIAI_02875 2.2e-75 yqgA
OLEDPIAI_02876 5.2e-47 yqfZ M LysM domain
OLEDPIAI_02877 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OLEDPIAI_02878 4.3e-62 yqfX S membrane
OLEDPIAI_02879 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
OLEDPIAI_02880 1.9e-77 zur P Belongs to the Fur family
OLEDPIAI_02881 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OLEDPIAI_02882 2.1e-36 yqfT S Protein of unknown function (DUF2624)
OLEDPIAI_02883 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OLEDPIAI_02884 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OLEDPIAI_02885 2.9e-14 yqfQ S YqfQ-like protein
OLEDPIAI_02886 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OLEDPIAI_02887 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OLEDPIAI_02888 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
OLEDPIAI_02889 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
OLEDPIAI_02890 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OLEDPIAI_02891 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OLEDPIAI_02892 4.5e-88 yaiI S Belongs to the UPF0178 family
OLEDPIAI_02893 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OLEDPIAI_02894 4.5e-112 ccpN K CBS domain
OLEDPIAI_02895 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OLEDPIAI_02896 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OLEDPIAI_02897 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
OLEDPIAI_02898 8.4e-19 S YqzL-like protein
OLEDPIAI_02899 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OLEDPIAI_02900 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OLEDPIAI_02901 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OLEDPIAI_02902 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OLEDPIAI_02903 0.0 yqfF S membrane-associated HD superfamily hydrolase
OLEDPIAI_02905 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
OLEDPIAI_02906 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
OLEDPIAI_02907 2.7e-45 yqfC S sporulation protein YqfC
OLEDPIAI_02908 6e-25 yqfB
OLEDPIAI_02909 4.3e-122 yqfA S UPF0365 protein
OLEDPIAI_02910 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
OLEDPIAI_02911 2.5e-61 yqeY S Yqey-like protein
OLEDPIAI_02912 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OLEDPIAI_02913 1.6e-158 yqeW P COG1283 Na phosphate symporter
OLEDPIAI_02914 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
OLEDPIAI_02915 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OLEDPIAI_02916 5.4e-175 prmA J Methylates ribosomal protein L11
OLEDPIAI_02917 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OLEDPIAI_02918 0.0 dnaK O Heat shock 70 kDa protein
OLEDPIAI_02919 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OLEDPIAI_02920 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OLEDPIAI_02921 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
OLEDPIAI_02922 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OLEDPIAI_02923 1e-54 yqxA S Protein of unknown function (DUF3679)
OLEDPIAI_02924 6.9e-223 spoIIP M stage II sporulation protein P
OLEDPIAI_02925 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OLEDPIAI_02926 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
OLEDPIAI_02927 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
OLEDPIAI_02928 4.1e-15 S YqzM-like protein
OLEDPIAI_02929 0.0 comEC S Competence protein ComEC
OLEDPIAI_02930 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
OLEDPIAI_02931 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
OLEDPIAI_02932 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OLEDPIAI_02933 2.9e-139 yqeM Q Methyltransferase
OLEDPIAI_02934 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OLEDPIAI_02935 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OLEDPIAI_02936 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OLEDPIAI_02937 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
OLEDPIAI_02938 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OLEDPIAI_02939 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OLEDPIAI_02940 5.3e-95 yqeG S hydrolase of the HAD superfamily
OLEDPIAI_02942 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
OLEDPIAI_02943 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OLEDPIAI_02944 4.7e-106 yqeD S SNARE associated Golgi protein
OLEDPIAI_02945 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
OLEDPIAI_02946 2.3e-133 yqeB
OLEDPIAI_02947 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
OLEDPIAI_02948 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLEDPIAI_02949 1.4e-281 cisA2 L Recombinase
OLEDPIAI_02950 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
OLEDPIAI_02951 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
OLEDPIAI_02952 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLEDPIAI_02953 1.6e-54 arsR K ArsR family transcriptional regulator
OLEDPIAI_02954 1.1e-152 yqcI S YqcI/YcgG family
OLEDPIAI_02955 1.6e-96 S Tetratricopeptide repeat
OLEDPIAI_02958 3.8e-277 A Pre-toxin TG
OLEDPIAI_02959 1.1e-104 S Suppressor of fused protein (SUFU)
OLEDPIAI_02961 5e-60
OLEDPIAI_02963 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OLEDPIAI_02964 2.6e-68 S Bacteriophage holin family
OLEDPIAI_02965 4.8e-165 xepA
OLEDPIAI_02966 1.3e-23
OLEDPIAI_02967 4.1e-56 xkdW S XkdW protein
OLEDPIAI_02968 2e-221
OLEDPIAI_02969 9.6e-40
OLEDPIAI_02970 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OLEDPIAI_02971 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OLEDPIAI_02972 9.6e-71 xkdS S Protein of unknown function (DUF2634)
OLEDPIAI_02973 1.8e-38 xkdR S Protein of unknown function (DUF2577)
OLEDPIAI_02974 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
OLEDPIAI_02975 9e-114 xkdP S Lysin motif
OLEDPIAI_02976 0.0 xkdO L Transglycosylase SLT domain
OLEDPIAI_02977 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
OLEDPIAI_02979 3.6e-76 xkdM S Phage tail tube protein
OLEDPIAI_02980 5.5e-256 xkdK S Phage tail sheath C-terminal domain
OLEDPIAI_02981 3.2e-26
OLEDPIAI_02982 1.4e-77
OLEDPIAI_02983 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
OLEDPIAI_02984 6.7e-65 yqbH S Domain of unknown function (DUF3599)
OLEDPIAI_02985 2.1e-67 S Protein of unknown function (DUF3199)
OLEDPIAI_02986 3.6e-51 S YqbF, hypothetical protein domain
OLEDPIAI_02987 1.9e-167 xkdG S Phage capsid family
OLEDPIAI_02988 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
OLEDPIAI_02989 2e-115
OLEDPIAI_02990 5.7e-169 S Phage Mu protein F like protein
OLEDPIAI_02991 5.9e-296 yqbA S portal protein
OLEDPIAI_02992 2.4e-253 S phage terminase, large subunit
OLEDPIAI_02993 6.3e-107 yqaS L DNA packaging
OLEDPIAI_02995 6.5e-81 L Transposase
OLEDPIAI_02996 1.6e-166
OLEDPIAI_02997 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
OLEDPIAI_02998 7.2e-74 rusA L Endodeoxyribonuclease RusA
OLEDPIAI_03000 5.9e-168 xkdC L IstB-like ATP binding protein
OLEDPIAI_03001 1e-122 3.1.3.16 L DnaD domain protein
OLEDPIAI_03002 2.5e-155 recT L RecT family
OLEDPIAI_03003 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
OLEDPIAI_03007 1.2e-103
OLEDPIAI_03009 6.5e-37 K Helix-turn-helix XRE-family like proteins
OLEDPIAI_03010 1.1e-56 K sequence-specific DNA binding
OLEDPIAI_03012 1e-101 adk 2.7.4.3 F adenylate kinase activity
OLEDPIAI_03013 1.4e-100 yqaB E IrrE N-terminal-like domain
OLEDPIAI_03014 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLEDPIAI_03015 2e-68 psiE S Protein PsiE homolog
OLEDPIAI_03016 9e-237 yrkQ T Histidine kinase
OLEDPIAI_03017 1.1e-127 T Transcriptional regulator
OLEDPIAI_03018 8.2e-224 yrkO P Protein of unknown function (DUF418)
OLEDPIAI_03019 6e-105 yrkN K Acetyltransferase (GNAT) family
OLEDPIAI_03020 1.5e-97 ywrO S Flavodoxin-like fold
OLEDPIAI_03021 2.8e-79 S Protein of unknown function with HXXEE motif
OLEDPIAI_03022 4.3e-117 yrkJ S membrane transporter protein
OLEDPIAI_03023 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
OLEDPIAI_03024 2.3e-212 yrkH P Rhodanese Homology Domain
OLEDPIAI_03025 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
OLEDPIAI_03026 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
OLEDPIAI_03027 7.8e-39 yrkD S protein conserved in bacteria
OLEDPIAI_03028 2.6e-108 yrkC G Cupin domain
OLEDPIAI_03029 4.8e-151 bltR K helix_turn_helix, mercury resistance
OLEDPIAI_03030 3.5e-211 blt EGP Major facilitator Superfamily
OLEDPIAI_03031 1.4e-83 bltD 2.3.1.57 K FR47-like protein
OLEDPIAI_03032 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OLEDPIAI_03033 2.1e-17 S YrzO-like protein
OLEDPIAI_03034 1.7e-171 yrdR EG EamA-like transporter family
OLEDPIAI_03035 5.9e-160 yrdQ K Transcriptional regulator
OLEDPIAI_03036 2e-199 trkA P Oxidoreductase
OLEDPIAI_03037 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
OLEDPIAI_03038 1.3e-66 yodA S tautomerase
OLEDPIAI_03039 7.7e-163 gltR K LysR substrate binding domain
OLEDPIAI_03041 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
OLEDPIAI_03042 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
OLEDPIAI_03043 3.3e-138 azlC E AzlC protein
OLEDPIAI_03044 2.2e-79 bkdR K helix_turn_helix ASNC type
OLEDPIAI_03045 4.1e-46 yrdF K ribonuclease inhibitor
OLEDPIAI_03046 4.1e-231 cypA C Cytochrome P450
OLEDPIAI_03047 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
OLEDPIAI_03048 1.9e-57 S Protein of unknown function (DUF2568)
OLEDPIAI_03049 1.2e-91 yrdA S DinB family
OLEDPIAI_03050 7.6e-168 aadK G Streptomycin adenylyltransferase
OLEDPIAI_03051 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OLEDPIAI_03052 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OLEDPIAI_03053 3e-125 yrpD S Domain of unknown function, YrpD
OLEDPIAI_03055 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
OLEDPIAI_03056 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
OLEDPIAI_03057 4.5e-188 yrpG C Aldo/keto reductase family
OLEDPIAI_03058 9.5e-226 yraO C Citrate transporter
OLEDPIAI_03059 1.2e-163 yraN K Transcriptional regulator
OLEDPIAI_03060 2.4e-206 yraM S PrpF protein
OLEDPIAI_03062 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
OLEDPIAI_03063 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLEDPIAI_03064 3.2e-155 S Alpha beta hydrolase
OLEDPIAI_03065 1.7e-60 T sh3 domain protein
OLEDPIAI_03066 2.4e-61 T sh3 domain protein
OLEDPIAI_03067 1.3e-66 E Glyoxalase-like domain
OLEDPIAI_03068 5.3e-37 yraG
OLEDPIAI_03069 6.4e-63 yraF M Spore coat protein
OLEDPIAI_03070 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OLEDPIAI_03071 2.6e-26 yraE
OLEDPIAI_03072 1.1e-49 yraD M Spore coat protein
OLEDPIAI_03073 4.3e-47 yraB K helix_turn_helix, mercury resistance
OLEDPIAI_03074 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
OLEDPIAI_03075 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
OLEDPIAI_03076 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
OLEDPIAI_03077 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
OLEDPIAI_03078 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
OLEDPIAI_03079 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
OLEDPIAI_03080 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
OLEDPIAI_03081 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
OLEDPIAI_03082 0.0 levR K PTS system fructose IIA component
OLEDPIAI_03083 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
OLEDPIAI_03084 3.6e-106 yrhP E LysE type translocator
OLEDPIAI_03085 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
OLEDPIAI_03086 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OLEDPIAI_03087 1.7e-151 rsiV S Protein of unknown function (DUF3298)
OLEDPIAI_03088 0.0 yrhL I Acyltransferase family
OLEDPIAI_03089 1.5e-46 yrhK S YrhK-like protein
OLEDPIAI_03090 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OLEDPIAI_03091 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
OLEDPIAI_03092 4.5e-97 yrhH Q methyltransferase
OLEDPIAI_03095 1.8e-142 focA P Formate nitrite
OLEDPIAI_03096 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
OLEDPIAI_03097 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
OLEDPIAI_03098 1.4e-78 yrhD S Protein of unknown function (DUF1641)
OLEDPIAI_03099 4.6e-35 yrhC S YrhC-like protein
OLEDPIAI_03100 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OLEDPIAI_03101 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
OLEDPIAI_03102 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OLEDPIAI_03103 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
OLEDPIAI_03104 3.5e-26 yrzA S Protein of unknown function (DUF2536)
OLEDPIAI_03105 4.2e-63 yrrS S Protein of unknown function (DUF1510)
OLEDPIAI_03106 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
OLEDPIAI_03107 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OLEDPIAI_03108 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
OLEDPIAI_03109 2.7e-246 yegQ O COG0826 Collagenase and related proteases
OLEDPIAI_03110 7.8e-174 yegQ O Peptidase U32
OLEDPIAI_03111 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
OLEDPIAI_03112 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OLEDPIAI_03113 1.2e-45 yrzB S Belongs to the UPF0473 family
OLEDPIAI_03114 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OLEDPIAI_03115 1.7e-41 yrzL S Belongs to the UPF0297 family
OLEDPIAI_03116 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OLEDPIAI_03117 2.7e-170 yrrI S AI-2E family transporter
OLEDPIAI_03118 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OLEDPIAI_03119 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
OLEDPIAI_03120 3.6e-109 gluC P ABC transporter
OLEDPIAI_03121 7.6e-107 glnP P ABC transporter
OLEDPIAI_03122 8e-08 S Protein of unknown function (DUF3918)
OLEDPIAI_03123 9.8e-31 yrzR
OLEDPIAI_03124 1.8e-83 yrrD S protein conserved in bacteria
OLEDPIAI_03125 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OLEDPIAI_03126 1.4e-15 S COG0457 FOG TPR repeat
OLEDPIAI_03127 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OLEDPIAI_03128 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
OLEDPIAI_03129 1.2e-70 cymR K Transcriptional regulator
OLEDPIAI_03130 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OLEDPIAI_03131 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OLEDPIAI_03132 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OLEDPIAI_03133 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
OLEDPIAI_03135 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
OLEDPIAI_03136 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OLEDPIAI_03137 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OLEDPIAI_03138 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OLEDPIAI_03139 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OLEDPIAI_03140 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
OLEDPIAI_03141 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
OLEDPIAI_03142 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OLEDPIAI_03143 9.4e-49 yrzD S Post-transcriptional regulator
OLEDPIAI_03144 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLEDPIAI_03145 2.2e-114 yrbG S membrane
OLEDPIAI_03146 1.2e-74 yrzE S Protein of unknown function (DUF3792)
OLEDPIAI_03147 1.1e-38 yajC U Preprotein translocase subunit YajC
OLEDPIAI_03148 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OLEDPIAI_03149 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OLEDPIAI_03150 2.6e-18 yrzS S Protein of unknown function (DUF2905)
OLEDPIAI_03151 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OLEDPIAI_03152 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OLEDPIAI_03153 4.8e-93 bofC S BofC C-terminal domain
OLEDPIAI_03154 5.3e-253 csbX EGP Major facilitator Superfamily
OLEDPIAI_03155 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
OLEDPIAI_03156 6.5e-119 yrzF T serine threonine protein kinase
OLEDPIAI_03158 2.6e-35 S Family of unknown function (DUF5412)
OLEDPIAI_03159 1.8e-262 alsT E Sodium alanine symporter
OLEDPIAI_03160 1.9e-127 yebC K transcriptional regulatory protein
OLEDPIAI_03161 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OLEDPIAI_03162 9.8e-158 safA M spore coat assembly protein SafA
OLEDPIAI_03163 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OLEDPIAI_03164 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
OLEDPIAI_03165 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
OLEDPIAI_03166 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
OLEDPIAI_03167 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
OLEDPIAI_03168 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
OLEDPIAI_03169 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
OLEDPIAI_03170 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OLEDPIAI_03171 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
OLEDPIAI_03172 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OLEDPIAI_03173 4.1e-56 ysxB J ribosomal protein
OLEDPIAI_03174 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
OLEDPIAI_03175 9.2e-161 spoIVFB S Stage IV sporulation protein
OLEDPIAI_03176 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
OLEDPIAI_03177 2.5e-144 minD D Belongs to the ParA family
OLEDPIAI_03178 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OLEDPIAI_03179 1.4e-84 mreD M shape-determining protein
OLEDPIAI_03180 2.8e-157 mreC M Involved in formation and maintenance of cell shape
OLEDPIAI_03181 1.8e-184 mreB D Rod shape-determining protein MreB
OLEDPIAI_03182 5.9e-126 radC E Belongs to the UPF0758 family
OLEDPIAI_03183 2.8e-102 maf D septum formation protein Maf
OLEDPIAI_03184 1.1e-168 spoIIB S Sporulation related domain
OLEDPIAI_03185 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OLEDPIAI_03186 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OLEDPIAI_03187 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OLEDPIAI_03188 1.6e-25
OLEDPIAI_03189 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OLEDPIAI_03190 1.9e-226 spoVID M stage VI sporulation protein D
OLEDPIAI_03191 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OLEDPIAI_03192 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
OLEDPIAI_03193 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OLEDPIAI_03194 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OLEDPIAI_03195 3.6e-146 hemX O cytochrome C
OLEDPIAI_03196 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OLEDPIAI_03197 1.4e-89 ysxD
OLEDPIAI_03198 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
OLEDPIAI_03199 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OLEDPIAI_03200 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
OLEDPIAI_03201 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OLEDPIAI_03202 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OLEDPIAI_03203 2.3e-187 ysoA H Tetratricopeptide repeat
OLEDPIAI_03204 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OLEDPIAI_03205 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OLEDPIAI_03206 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OLEDPIAI_03207 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OLEDPIAI_03208 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OLEDPIAI_03209 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
OLEDPIAI_03210 0.0 ilvB 2.2.1.6 E Acetolactate synthase
OLEDPIAI_03212 7.6e-82 ysnE K acetyltransferase
OLEDPIAI_03213 9.1e-134 ysnF S protein conserved in bacteria
OLEDPIAI_03215 1.4e-92 ysnB S Phosphoesterase
OLEDPIAI_03216 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OLEDPIAI_03217 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OLEDPIAI_03218 2.9e-196 gerM S COG5401 Spore germination protein
OLEDPIAI_03219 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OLEDPIAI_03220 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
OLEDPIAI_03221 3.3e-30 gerE K Transcriptional regulator
OLEDPIAI_03222 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
OLEDPIAI_03223 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OLEDPIAI_03224 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OLEDPIAI_03225 2.4e-107 sdhC C succinate dehydrogenase
OLEDPIAI_03226 1.2e-79 yslB S Protein of unknown function (DUF2507)
OLEDPIAI_03227 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OLEDPIAI_03228 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OLEDPIAI_03229 2e-52 trxA O Belongs to the thioredoxin family
OLEDPIAI_03230 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
OLEDPIAI_03232 4.2e-178 etfA C Electron transfer flavoprotein
OLEDPIAI_03233 1.2e-135 etfB C Electron transfer flavoprotein
OLEDPIAI_03234 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OLEDPIAI_03235 2.7e-100 fadR K Transcriptional regulator
OLEDPIAI_03236 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OLEDPIAI_03237 7.3e-68 yshE S membrane
OLEDPIAI_03238 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OLEDPIAI_03239 0.0 polX L COG1796 DNA polymerase IV (family X)
OLEDPIAI_03240 1.3e-85 cvpA S membrane protein, required for colicin V production
OLEDPIAI_03241 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OLEDPIAI_03242 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OLEDPIAI_03243 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OLEDPIAI_03244 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OLEDPIAI_03245 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OLEDPIAI_03246 2.6e-32 sspI S Belongs to the SspI family
OLEDPIAI_03247 4.4e-208 ysfB KT regulator
OLEDPIAI_03248 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
OLEDPIAI_03249 5.6e-258 glcF C Glycolate oxidase
OLEDPIAI_03250 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
OLEDPIAI_03252 0.0 cstA T Carbon starvation protein
OLEDPIAI_03253 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
OLEDPIAI_03254 3.4e-144 araQ G transport system permease
OLEDPIAI_03255 1.4e-167 araP G carbohydrate transport
OLEDPIAI_03256 2.8e-254 araN G carbohydrate transport
OLEDPIAI_03257 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
OLEDPIAI_03258 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
OLEDPIAI_03259 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
OLEDPIAI_03260 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
OLEDPIAI_03261 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OLEDPIAI_03262 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OLEDPIAI_03263 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
OLEDPIAI_03264 9.2e-68 ysdB S Sigma-w pathway protein YsdB
OLEDPIAI_03265 7.5e-45 ysdA S Membrane
OLEDPIAI_03266 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OLEDPIAI_03267 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OLEDPIAI_03268 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OLEDPIAI_03270 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OLEDPIAI_03271 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OLEDPIAI_03272 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
OLEDPIAI_03273 0.0 lytS 2.7.13.3 T Histidine kinase
OLEDPIAI_03274 1.5e-149 ysaA S HAD-hyrolase-like
OLEDPIAI_03275 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OLEDPIAI_03276 3.8e-159 ytxC S YtxC-like family
OLEDPIAI_03277 4.9e-111 ytxB S SNARE associated Golgi protein
OLEDPIAI_03278 3e-173 dnaI L Primosomal protein DnaI
OLEDPIAI_03279 3.5e-266 dnaB L Membrane attachment protein
OLEDPIAI_03280 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OLEDPIAI_03281 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OLEDPIAI_03282 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OLEDPIAI_03283 9.9e-67 ytcD K Transcriptional regulator
OLEDPIAI_03284 4.9e-205 ytbD EGP Major facilitator Superfamily
OLEDPIAI_03285 8.9e-161 ytbE S reductase
OLEDPIAI_03286 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OLEDPIAI_03287 1.1e-107 ytaF P Probably functions as a manganese efflux pump
OLEDPIAI_03288 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OLEDPIAI_03289 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OLEDPIAI_03290 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
OLEDPIAI_03291 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_03292 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
OLEDPIAI_03293 1.8e-242 icd 1.1.1.42 C isocitrate
OLEDPIAI_03294 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
OLEDPIAI_03295 4.7e-71 yeaL S membrane
OLEDPIAI_03296 2.6e-192 ytvI S sporulation integral membrane protein YtvI
OLEDPIAI_03297 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
OLEDPIAI_03298 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OLEDPIAI_03299 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OLEDPIAI_03300 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OLEDPIAI_03301 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OLEDPIAI_03302 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
OLEDPIAI_03303 0.0 dnaE 2.7.7.7 L DNA polymerase
OLEDPIAI_03304 3.2e-56 ytrH S Sporulation protein YtrH
OLEDPIAI_03305 8.2e-69 ytrI
OLEDPIAI_03306 9.2e-29
OLEDPIAI_03307 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
OLEDPIAI_03308 2.4e-47 ytpI S YtpI-like protein
OLEDPIAI_03309 8e-241 ytoI K transcriptional regulator containing CBS domains
OLEDPIAI_03310 1.2e-158 ytnM S membrane transporter protein
OLEDPIAI_03311 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
OLEDPIAI_03312 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
OLEDPIAI_03313 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLEDPIAI_03314 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
OLEDPIAI_03315 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLEDPIAI_03316 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OLEDPIAI_03317 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
OLEDPIAI_03318 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
OLEDPIAI_03319 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
OLEDPIAI_03320 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
OLEDPIAI_03321 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
OLEDPIAI_03322 2.9e-173 ytlI K LysR substrate binding domain
OLEDPIAI_03323 1.7e-130 ytkL S Belongs to the UPF0173 family
OLEDPIAI_03324 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLEDPIAI_03326 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
OLEDPIAI_03327 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OLEDPIAI_03328 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
OLEDPIAI_03329 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OLEDPIAI_03330 3.5e-164 ytxK 2.1.1.72 L DNA methylase
OLEDPIAI_03331 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OLEDPIAI_03332 8.7e-70 ytfJ S Sporulation protein YtfJ
OLEDPIAI_03333 5.6e-116 ytfI S Protein of unknown function (DUF2953)
OLEDPIAI_03334 1.3e-87 yteJ S RDD family
OLEDPIAI_03335 2.4e-181 sppA OU signal peptide peptidase SppA
OLEDPIAI_03336 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OLEDPIAI_03337 0.0 ytcJ S amidohydrolase
OLEDPIAI_03338 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OLEDPIAI_03339 2e-29 sspB S spore protein
OLEDPIAI_03340 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OLEDPIAI_03341 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
OLEDPIAI_03342 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
OLEDPIAI_03343 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OLEDPIAI_03344 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
OLEDPIAI_03345 3.4e-109 yttP K Transcriptional regulator
OLEDPIAI_03346 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
OLEDPIAI_03347 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
OLEDPIAI_03348 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OLEDPIAI_03350 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OLEDPIAI_03351 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OLEDPIAI_03352 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OLEDPIAI_03353 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
OLEDPIAI_03354 1.9e-225 acuC BQ histone deacetylase
OLEDPIAI_03355 1.4e-125 motS N Flagellar motor protein
OLEDPIAI_03356 7.1e-147 motA N flagellar motor
OLEDPIAI_03357 1.7e-182 ccpA K catabolite control protein A
OLEDPIAI_03358 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OLEDPIAI_03359 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
OLEDPIAI_03360 6.6e-17 ytxH S COG4980 Gas vesicle protein
OLEDPIAI_03361 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OLEDPIAI_03362 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OLEDPIAI_03363 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OLEDPIAI_03364 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OLEDPIAI_03365 9.8e-149 ytpQ S Belongs to the UPF0354 family
OLEDPIAI_03366 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OLEDPIAI_03367 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
OLEDPIAI_03368 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
OLEDPIAI_03369 9.8e-52 ytzB S small secreted protein
OLEDPIAI_03370 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
OLEDPIAI_03371 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
OLEDPIAI_03372 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OLEDPIAI_03373 2e-45 ytzH S YtzH-like protein
OLEDPIAI_03374 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
OLEDPIAI_03375 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
OLEDPIAI_03376 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
OLEDPIAI_03377 1.3e-165 ytlQ
OLEDPIAI_03378 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OLEDPIAI_03379 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OLEDPIAI_03380 7.1e-272 pepV 3.5.1.18 E Dipeptidase
OLEDPIAI_03381 7.2e-226 pbuO S permease
OLEDPIAI_03382 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
OLEDPIAI_03383 4.3e-132 ythP V ABC transporter
OLEDPIAI_03384 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
OLEDPIAI_03385 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OLEDPIAI_03386 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLEDPIAI_03387 8.2e-232 ytfP S HI0933-like protein
OLEDPIAI_03388 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
OLEDPIAI_03389 3.1e-26 yteV S Sporulation protein Cse60
OLEDPIAI_03390 4.8e-117 yteU S Integral membrane protein
OLEDPIAI_03391 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
OLEDPIAI_03392 4.6e-73 yteS G transport
OLEDPIAI_03393 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
OLEDPIAI_03394 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
OLEDPIAI_03395 0.0 ytdP K Transcriptional regulator
OLEDPIAI_03396 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
OLEDPIAI_03397 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
OLEDPIAI_03398 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
OLEDPIAI_03399 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
OLEDPIAI_03400 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OLEDPIAI_03401 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OLEDPIAI_03402 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OLEDPIAI_03403 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
OLEDPIAI_03404 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OLEDPIAI_03405 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
OLEDPIAI_03406 2.3e-190 msmR K Transcriptional regulator
OLEDPIAI_03407 2.3e-248 msmE G Bacterial extracellular solute-binding protein
OLEDPIAI_03408 3.7e-168 amyD P ABC transporter
OLEDPIAI_03409 1.5e-144 amyC P ABC transporter (permease)
OLEDPIAI_03410 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OLEDPIAI_03411 2.1e-51 ytwF P Sulfurtransferase
OLEDPIAI_03412 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OLEDPIAI_03413 7.7e-55 ytvB S Protein of unknown function (DUF4257)
OLEDPIAI_03414 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
OLEDPIAI_03415 2.1e-211 yttB EGP Major facilitator Superfamily
OLEDPIAI_03416 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
OLEDPIAI_03417 0.0 bceB V ABC transporter (permease)
OLEDPIAI_03418 1.1e-138 bceA V ABC transporter, ATP-binding protein
OLEDPIAI_03419 5.6e-186 T PhoQ Sensor
OLEDPIAI_03420 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_03421 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
OLEDPIAI_03422 3.1e-127 ytrE V ABC transporter, ATP-binding protein
OLEDPIAI_03423 5.9e-148
OLEDPIAI_03424 6.1e-169 P ABC-2 family transporter protein
OLEDPIAI_03425 1.1e-161 ytrB P abc transporter atp-binding protein
OLEDPIAI_03426 5.1e-66 ytrA K GntR family transcriptional regulator
OLEDPIAI_03428 6.7e-41 ytzC S Protein of unknown function (DUF2524)
OLEDPIAI_03429 2.1e-190 yhcC S Fe-S oxidoreductase
OLEDPIAI_03430 3.3e-106 ytqB J Putative rRNA methylase
OLEDPIAI_03431 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
OLEDPIAI_03432 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
OLEDPIAI_03433 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OLEDPIAI_03434 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
OLEDPIAI_03435 0.0 asnB 6.3.5.4 E Asparagine synthase
OLEDPIAI_03436 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OLEDPIAI_03437 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OLEDPIAI_03438 1.2e-38 ytmB S Protein of unknown function (DUF2584)
OLEDPIAI_03439 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OLEDPIAI_03440 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OLEDPIAI_03441 1.4e-144 ytlC P ABC transporter
OLEDPIAI_03442 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OLEDPIAI_03443 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
OLEDPIAI_03444 5.4e-63 ytkC S Bacteriophage holin family
OLEDPIAI_03445 2.1e-76 dps P Belongs to the Dps family
OLEDPIAI_03447 3.6e-73 ytkA S YtkA-like
OLEDPIAI_03448 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OLEDPIAI_03449 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OLEDPIAI_03450 3.6e-41 rpmE2 J Ribosomal protein L31
OLEDPIAI_03451 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
OLEDPIAI_03452 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
OLEDPIAI_03453 1.1e-24 S Domain of Unknown Function (DUF1540)
OLEDPIAI_03454 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
OLEDPIAI_03455 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OLEDPIAI_03456 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OLEDPIAI_03457 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
OLEDPIAI_03458 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OLEDPIAI_03459 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OLEDPIAI_03460 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OLEDPIAI_03461 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OLEDPIAI_03462 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OLEDPIAI_03463 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
OLEDPIAI_03464 2.6e-132 dksA T COG1734 DnaK suppressor protein
OLEDPIAI_03465 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
OLEDPIAI_03466 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OLEDPIAI_03467 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
OLEDPIAI_03468 3.6e-235 ytcC M Glycosyltransferase Family 4
OLEDPIAI_03470 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
OLEDPIAI_03471 1.8e-217 cotSA M Glycosyl transferases group 1
OLEDPIAI_03472 1.8e-206 cotI S Spore coat protein
OLEDPIAI_03473 9.9e-77 tspO T membrane
OLEDPIAI_03474 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
OLEDPIAI_03475 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
OLEDPIAI_03476 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
OLEDPIAI_03477 8e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OLEDPIAI_03478 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OLEDPIAI_03487 7.8e-08
OLEDPIAI_03488 1.3e-09
OLEDPIAI_03495 2e-08
OLEDPIAI_03502 2.8e-193 xerH A Belongs to the 'phage' integrase family
OLEDPIAI_03503 6.3e-70
OLEDPIAI_03504 2.5e-86
OLEDPIAI_03505 2.5e-10 xkdX
OLEDPIAI_03506 8.1e-07
OLEDPIAI_03507 1.1e-172
OLEDPIAI_03508 1e-57
OLEDPIAI_03511 1.6e-90
OLEDPIAI_03512 8.1e-131
OLEDPIAI_03513 2.6e-91
OLEDPIAI_03514 1.4e-121
OLEDPIAI_03516 1.1e-68
OLEDPIAI_03517 5.1e-81
OLEDPIAI_03518 5.7e-186
OLEDPIAI_03519 1.6e-94
OLEDPIAI_03520 2.1e-266
OLEDPIAI_03521 6.3e-282
OLEDPIAI_03522 0.0 gp17a S Terminase-like family
OLEDPIAI_03523 1.8e-175
OLEDPIAI_03526 2.6e-230
OLEDPIAI_03528 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OLEDPIAI_03529 0.0
OLEDPIAI_03532 5.7e-55 bldD K domain, Protein
OLEDPIAI_03533 4e-17
OLEDPIAI_03535 5.9e-238
OLEDPIAI_03537 1.4e-256
OLEDPIAI_03538 4.6e-35 K Cro/C1-type HTH DNA-binding domain
OLEDPIAI_03539 3.8e-259
OLEDPIAI_03540 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
OLEDPIAI_03545 1.1e-96 S Super-infection exclusion protein B
OLEDPIAI_03546 1.2e-86
OLEDPIAI_03548 6.6e-106
OLEDPIAI_03553 6.8e-198 L Belongs to the 'phage' integrase family
OLEDPIAI_03554 6e-263 S DNA-sulfur modification-associated
OLEDPIAI_03555 2.1e-177
OLEDPIAI_03556 1.1e-33 K Transcriptional regulator
OLEDPIAI_03567 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
OLEDPIAI_03568 8.8e-12 S Protein of unknown function (DUF2815)
OLEDPIAI_03571 3e-78 yoqH M LysM domain
OLEDPIAI_03573 1.5e-97 S Protein of unknown function (DUF1273)
OLEDPIAI_03575 1e-44
OLEDPIAI_03582 2.3e-77
OLEDPIAI_03583 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
OLEDPIAI_03584 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
OLEDPIAI_03587 7.7e-149 S Pfam:DUF867
OLEDPIAI_03588 0.0 M Parallel beta-helix repeats
OLEDPIAI_03593 1.3e-170
OLEDPIAI_03594 7.6e-180 L AAA domain
OLEDPIAI_03595 1.4e-86
OLEDPIAI_03596 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
OLEDPIAI_03597 1.3e-223 L DNA primase activity
OLEDPIAI_03598 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OLEDPIAI_03599 0.0 2.7.7.7 L DNA polymerase
OLEDPIAI_03600 9.9e-115 DR0488 S protein conserved in bacteria
OLEDPIAI_03605 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
OLEDPIAI_03606 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
OLEDPIAI_03608 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
OLEDPIAI_03625 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OLEDPIAI_03626 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLEDPIAI_03627 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLEDPIAI_03628 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLEDPIAI_03629 3.3e-97 L HNH endonuclease
OLEDPIAI_03630 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLEDPIAI_03631 6.1e-38 O Glutaredoxin
OLEDPIAI_03632 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OLEDPIAI_03633 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
OLEDPIAI_03637 3.1e-38 S Protein of unknown function (DUF1643)
OLEDPIAI_03638 3.7e-159 S Thymidylate synthase
OLEDPIAI_03640 2.5e-30 sspB S spore protein
OLEDPIAI_03641 1.9e-168 S Calcineurin-like phosphoesterase
OLEDPIAI_03649 1.4e-10 K Cro/C1-type HTH DNA-binding domain
OLEDPIAI_03650 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OLEDPIAI_03652 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
OLEDPIAI_03653 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
OLEDPIAI_03654 3.3e-188 cgeB S Spore maturation protein
OLEDPIAI_03655 1.2e-65 cgeA
OLEDPIAI_03656 3.5e-38 cgeC
OLEDPIAI_03657 1e-256 cgeD M maturation of the outermost layer of the spore
OLEDPIAI_03658 2.9e-145 yiiD K acetyltransferase
OLEDPIAI_03661 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OLEDPIAI_03662 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OLEDPIAI_03663 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OLEDPIAI_03664 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
OLEDPIAI_03665 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
OLEDPIAI_03666 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
OLEDPIAI_03667 2.9e-47 yokU S YokU-like protein, putative antitoxin
OLEDPIAI_03668 1.4e-36 yozE S Belongs to the UPF0346 family
OLEDPIAI_03669 1.4e-124 yodN
OLEDPIAI_03671 2.8e-24 yozD S YozD-like protein
OLEDPIAI_03672 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
OLEDPIAI_03673 3.6e-54 yodL S YodL-like
OLEDPIAI_03674 5.3e-09
OLEDPIAI_03675 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OLEDPIAI_03676 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OLEDPIAI_03677 5.2e-24 yodI
OLEDPIAI_03678 1.7e-128 yodH Q Methyltransferase
OLEDPIAI_03679 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OLEDPIAI_03680 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OLEDPIAI_03681 6.2e-28 S Protein of unknown function (DUF3311)
OLEDPIAI_03682 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
OLEDPIAI_03683 3.8e-113 mhqD S Carboxylesterase
OLEDPIAI_03684 4.8e-108 yodC C nitroreductase
OLEDPIAI_03685 1.7e-57 yodB K transcriptional
OLEDPIAI_03686 3.8e-66 yodA S tautomerase
OLEDPIAI_03687 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
OLEDPIAI_03688 3.4e-09
OLEDPIAI_03689 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
OLEDPIAI_03690 3.5e-163 rarD S -transporter
OLEDPIAI_03691 1.5e-43
OLEDPIAI_03692 2.2e-60 yojF S Protein of unknown function (DUF1806)
OLEDPIAI_03693 2.1e-125 yojG S deacetylase
OLEDPIAI_03694 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OLEDPIAI_03695 4.2e-245 norM V Multidrug efflux pump
OLEDPIAI_03697 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OLEDPIAI_03698 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
OLEDPIAI_03699 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OLEDPIAI_03700 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OLEDPIAI_03701 1.2e-160 yojN S ATPase family associated with various cellular activities (AAA)
OLEDPIAI_03702 0.0 yojO P Von Willebrand factor
OLEDPIAI_03703 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OLEDPIAI_03704 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OLEDPIAI_03705 5.1e-168 yocS S -transporter
OLEDPIAI_03706 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OLEDPIAI_03707 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
OLEDPIAI_03708 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
OLEDPIAI_03709 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
OLEDPIAI_03710 2.7e-31 yozC
OLEDPIAI_03711 4.2e-56 yozO S Bacterial PH domain
OLEDPIAI_03712 1.9e-36 yocN
OLEDPIAI_03713 1.1e-40 yozN
OLEDPIAI_03714 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
OLEDPIAI_03715 6.6e-34
OLEDPIAI_03716 6.4e-54 yocL
OLEDPIAI_03717 3.3e-83 dksA T general stress protein
OLEDPIAI_03718 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OLEDPIAI_03719 0.0 recQ 3.6.4.12 L DNA helicase
OLEDPIAI_03720 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
OLEDPIAI_03721 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLEDPIAI_03722 3.2e-198 desK 2.7.13.3 T Histidine kinase
OLEDPIAI_03723 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
OLEDPIAI_03724 6.9e-189 yocD 3.4.17.13 V peptidase S66
OLEDPIAI_03725 1.9e-94 yocC
OLEDPIAI_03726 2.2e-145
OLEDPIAI_03727 1.5e-92 yozB S membrane
OLEDPIAI_03728 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OLEDPIAI_03729 1e-51 czrA K transcriptional
OLEDPIAI_03730 2.5e-95 yobW
OLEDPIAI_03731 9e-178 yobV K WYL domain
OLEDPIAI_03732 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
OLEDPIAI_03733 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
OLEDPIAI_03734 3e-99 yobS K Transcriptional regulator
OLEDPIAI_03735 2.5e-143 yobR 2.3.1.1 J FR47-like protein
OLEDPIAI_03736 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
OLEDPIAI_03737 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
OLEDPIAI_03738 0.0 yobO M Pectate lyase superfamily protein
OLEDPIAI_03739 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
OLEDPIAI_03740 7.9e-105 yokH G SMI1 / KNR4 family
OLEDPIAI_03741 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OLEDPIAI_03742 3e-86 S SMI1-KNR4 cell-wall
OLEDPIAI_03743 2.7e-157 yobJ
OLEDPIAI_03744 0.0 K Psort location Cytoplasmic, score
OLEDPIAI_03745 1.2e-49
OLEDPIAI_03746 2.6e-38 S YolD-like protein
OLEDPIAI_03747 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OLEDPIAI_03748 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OLEDPIAI_03750 1.7e-207 S aspartate phosphatase
OLEDPIAI_03755 1.8e-178 yobF
OLEDPIAI_03756 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
OLEDPIAI_03757 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
OLEDPIAI_03759 5.7e-58 K Helix-turn-helix
OLEDPIAI_03760 1.4e-37 S TM2 domain
OLEDPIAI_03761 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
OLEDPIAI_03762 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
OLEDPIAI_03766 2.3e-170 bla 3.5.2.6 V beta-lactamase
OLEDPIAI_03767 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
OLEDPIAI_03768 3.7e-78 yoaW
OLEDPIAI_03769 6e-160 yijE EG EamA-like transporter family
OLEDPIAI_03770 8.6e-159 yoaU K LysR substrate binding domain
OLEDPIAI_03771 1.1e-149 yoaT S Protein of unknown function (DUF817)
OLEDPIAI_03772 4.2e-37 yozG K Transcriptional regulator
OLEDPIAI_03773 4.3e-75 yoaS S Protein of unknown function (DUF2975)
OLEDPIAI_03774 2.4e-172 yoaR V vancomycin resistance protein
OLEDPIAI_03775 4.1e-89
OLEDPIAI_03776 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
OLEDPIAI_03777 1.9e-146 yoaP 3.1.3.18 K YoaP-like
OLEDPIAI_03779 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
OLEDPIAI_03781 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
OLEDPIAI_03782 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
OLEDPIAI_03783 2.3e-111 yoaK S Membrane
OLEDPIAI_03784 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
OLEDPIAI_03785 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
OLEDPIAI_03786 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
OLEDPIAI_03787 1.5e-38 S Protein of unknown function (DUF4025)
OLEDPIAI_03788 7e-14
OLEDPIAI_03789 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
OLEDPIAI_03790 1.9e-33 yoaF
OLEDPIAI_03791 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OLEDPIAI_03792 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OLEDPIAI_03793 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
OLEDPIAI_03794 6.2e-235 yoaB EGP Major facilitator Superfamily
OLEDPIAI_03795 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OLEDPIAI_03796 3.1e-144 yoxB
OLEDPIAI_03797 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
OLEDPIAI_03798 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OLEDPIAI_03799 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OLEDPIAI_03800 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OLEDPIAI_03801 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OLEDPIAI_03802 7.8e-155 gltC K Transcriptional regulator
OLEDPIAI_03803 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
OLEDPIAI_03804 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OLEDPIAI_03805 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
OLEDPIAI_03806 2.5e-158 gltR1 K Transcriptional regulator
OLEDPIAI_03807 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OLEDPIAI_03808 3e-34 yoeD G Helix-turn-helix domain
OLEDPIAI_03809 2.2e-96 L Integrase
OLEDPIAI_03811 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
OLEDPIAI_03812 2.3e-246 yoeA V MATE efflux family protein
OLEDPIAI_03813 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
OLEDPIAI_03814 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
OLEDPIAI_03815 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
OLEDPIAI_03817 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
OLEDPIAI_03818 2.2e-142 ybbA S Putative esterase
OLEDPIAI_03819 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_03820 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_03821 7.2e-167 feuA P Iron-uptake system-binding protein
OLEDPIAI_03822 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
OLEDPIAI_03823 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
OLEDPIAI_03824 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
OLEDPIAI_03825 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
OLEDPIAI_03826 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLEDPIAI_03827 1.1e-150 ybbH K transcriptional
OLEDPIAI_03828 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OLEDPIAI_03829 6.4e-87 ybbJ J acetyltransferase
OLEDPIAI_03830 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
OLEDPIAI_03836 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OLEDPIAI_03837 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OLEDPIAI_03838 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OLEDPIAI_03839 3e-225 ybbR S protein conserved in bacteria
OLEDPIAI_03840 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OLEDPIAI_03841 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OLEDPIAI_03842 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OLEDPIAI_03843 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
OLEDPIAI_03844 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OLEDPIAI_03845 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OLEDPIAI_03846 0.0 ybcC S Belongs to the UPF0753 family
OLEDPIAI_03847 3.7e-96 can 4.2.1.1 P carbonic anhydrase
OLEDPIAI_03848 3.9e-47
OLEDPIAI_03849 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
OLEDPIAI_03850 5.1e-50 ybzH K Helix-turn-helix domain
OLEDPIAI_03851 2e-203 ybcL EGP Major facilitator Superfamily
OLEDPIAI_03853 9.1e-239 J 4Fe-4S single cluster domain
OLEDPIAI_03854 1.6e-277 V CAAX protease self-immunity
OLEDPIAI_03855 1.9e-135 skfE V ABC transporter
OLEDPIAI_03856 4e-248 skfF S ABC transporter
OLEDPIAI_03857 7.8e-91 C HEAT repeats
OLEDPIAI_03858 9.6e-79 txn CO Thioredoxin-like
OLEDPIAI_03859 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OLEDPIAI_03860 1.5e-123 T Transcriptional regulatory protein, C terminal
OLEDPIAI_03861 1.8e-173 T His Kinase A (phospho-acceptor) domain
OLEDPIAI_03863 1.6e-140 KLT Protein tyrosine kinase
OLEDPIAI_03864 4.8e-154 ybdN
OLEDPIAI_03865 1.5e-217 ybdO S Domain of unknown function (DUF4885)
OLEDPIAI_03866 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
OLEDPIAI_03867 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
OLEDPIAI_03868 4.9e-30 ybxH S Family of unknown function (DUF5370)
OLEDPIAI_03869 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
OLEDPIAI_03870 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
OLEDPIAI_03871 4.9e-41 ybyB
OLEDPIAI_03872 1.8e-290 ybeC E amino acid
OLEDPIAI_03873 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OLEDPIAI_03874 7.3e-258 glpT G -transporter
OLEDPIAI_03875 2.9e-35 S Protein of unknown function (DUF2651)
OLEDPIAI_03876 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
OLEDPIAI_03877 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
OLEDPIAI_03879 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
OLEDPIAI_03880 8.8e-162 ybfH EG EamA-like transporter family
OLEDPIAI_03881 2.3e-145 msmR K AraC-like ligand binding domain
OLEDPIAI_03882 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OLEDPIAI_03883 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
OLEDPIAI_03885 2.5e-169 S Alpha/beta hydrolase family
OLEDPIAI_03886 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OLEDPIAI_03887 2.7e-85 ybfM S SNARE associated Golgi protein
OLEDPIAI_03888 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
OLEDPIAI_03889 3.2e-46 ybfN
OLEDPIAI_03890 4.3e-258 S Erythromycin esterase
OLEDPIAI_03891 6.7e-167 ybfP K Transcriptional regulator
OLEDPIAI_03892 3.9e-192 yceA S Belongs to the UPF0176 family
OLEDPIAI_03893 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OLEDPIAI_03894 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLEDPIAI_03895 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OLEDPIAI_03896 4.9e-128 K UTRA
OLEDPIAI_03898 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OLEDPIAI_03899 6.7e-262 mmuP E amino acid
OLEDPIAI_03900 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
OLEDPIAI_03901 2.3e-257 agcS E Sodium alanine symporter
OLEDPIAI_03902 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
OLEDPIAI_03903 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
OLEDPIAI_03904 9e-170 glnL T Regulator
OLEDPIAI_03905 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
OLEDPIAI_03906 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OLEDPIAI_03907 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
OLEDPIAI_03908 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OLEDPIAI_03909 1.5e-124 ycbG K FCD
OLEDPIAI_03910 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
OLEDPIAI_03911 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
OLEDPIAI_03912 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
OLEDPIAI_03913 7.3e-172 eamA1 EG spore germination
OLEDPIAI_03914 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_03915 2.4e-170 T PhoQ Sensor
OLEDPIAI_03916 4.8e-168 ycbN V ABC transporter, ATP-binding protein
OLEDPIAI_03917 2.1e-115 S ABC-2 family transporter protein
OLEDPIAI_03918 8.2e-53 ycbP S Protein of unknown function (DUF2512)
OLEDPIAI_03919 1.3e-78 sleB 3.5.1.28 M Cell wall
OLEDPIAI_03920 6.6e-136 ycbR T vWA found in TerF C terminus
OLEDPIAI_03921 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
OLEDPIAI_03922 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OLEDPIAI_03923 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OLEDPIAI_03924 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OLEDPIAI_03925 6.2e-210 ycbU E Selenocysteine lyase
OLEDPIAI_03926 5.8e-229 lmrB EGP the major facilitator superfamily
OLEDPIAI_03927 4.8e-102 yxaF K Transcriptional regulator
OLEDPIAI_03928 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
OLEDPIAI_03929 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OLEDPIAI_03930 2e-59 S RDD family
OLEDPIAI_03931 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
OLEDPIAI_03932 2e-161 2.7.13.3 T GHKL domain
OLEDPIAI_03933 1.2e-126 lytR_2 T LytTr DNA-binding domain
OLEDPIAI_03934 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
OLEDPIAI_03935 4.5e-203 natB CP ABC-2 family transporter protein
OLEDPIAI_03936 1.6e-174 yccK C Aldo keto reductase
OLEDPIAI_03937 6.6e-177 ycdA S Domain of unknown function (DUF5105)
OLEDPIAI_03938 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
OLEDPIAI_03939 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
OLEDPIAI_03940 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
OLEDPIAI_03941 5.5e-174 S response regulator aspartate phosphatase
OLEDPIAI_03942 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
OLEDPIAI_03943 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
OLEDPIAI_03944 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
OLEDPIAI_03945 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OLEDPIAI_03946 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OLEDPIAI_03947 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLEDPIAI_03948 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
OLEDPIAI_03949 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
OLEDPIAI_03950 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
OLEDPIAI_03951 6.3e-137 terC P Protein of unknown function (DUF475)
OLEDPIAI_03952 0.0 yceG S Putative component of 'biosynthetic module'
OLEDPIAI_03953 2e-192 yceH P Belongs to the TelA family
OLEDPIAI_03954 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
OLEDPIAI_03955 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
OLEDPIAI_03956 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
OLEDPIAI_03957 5.1e-229 proV 3.6.3.32 E glycine betaine
OLEDPIAI_03958 1.3e-127 opuAB P glycine betaine
OLEDPIAI_03959 5.3e-164 opuAC E glycine betaine
OLEDPIAI_03960 1.2e-219 amhX S amidohydrolase
OLEDPIAI_03961 8.7e-257 ycgA S Membrane
OLEDPIAI_03962 1.1e-98 ycgB
OLEDPIAI_03963 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
OLEDPIAI_03964 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OLEDPIAI_03965 6.5e-293 lctP C L-lactate permease
OLEDPIAI_03966 6.2e-269 mdr EGP Major facilitator Superfamily
OLEDPIAI_03967 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
OLEDPIAI_03968 6.8e-113 ycgF E Lysine exporter protein LysE YggA
OLEDPIAI_03969 1.2e-151 yqcI S YqcI/YcgG family
OLEDPIAI_03970 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
OLEDPIAI_03971 2.4e-112 ycgI S Domain of unknown function (DUF1989)
OLEDPIAI_03972 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OLEDPIAI_03973 2.5e-109 tmrB S AAA domain
OLEDPIAI_03974 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OLEDPIAI_03975 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
OLEDPIAI_03976 2.2e-179 oxyR3 K LysR substrate binding domain
OLEDPIAI_03977 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
OLEDPIAI_03978 2.9e-145 ycgL S Predicted nucleotidyltransferase
OLEDPIAI_03979 5.1e-170 ycgM E Proline dehydrogenase
OLEDPIAI_03980 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OLEDPIAI_03981 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OLEDPIAI_03982 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
OLEDPIAI_03983 2.6e-147 ycgQ S membrane
OLEDPIAI_03984 1.2e-139 ycgR S permeases
OLEDPIAI_03985 5.7e-163 I alpha/beta hydrolase fold
OLEDPIAI_03986 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OLEDPIAI_03987 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OLEDPIAI_03988 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
OLEDPIAI_03989 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OLEDPIAI_03990 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OLEDPIAI_03991 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
OLEDPIAI_03992 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
OLEDPIAI_03993 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
OLEDPIAI_03994 5.5e-109 yciB M ErfK YbiS YcfS YnhG
OLEDPIAI_03995 1.4e-228 yciC S GTPases (G3E family)
OLEDPIAI_03996 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
OLEDPIAI_03997 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
OLEDPIAI_04000 3.3e-77 yckC S membrane
OLEDPIAI_04001 3.5e-52 yckD S Protein of unknown function (DUF2680)
OLEDPIAI_04002 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OLEDPIAI_04003 3.4e-70 nin S Competence protein J (ComJ)
OLEDPIAI_04004 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
OLEDPIAI_04005 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
OLEDPIAI_04006 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
OLEDPIAI_04007 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
OLEDPIAI_04008 1.3e-63 hxlR K transcriptional
OLEDPIAI_04010 5e-227 ydeG EGP Major facilitator Superfamily
OLEDPIAI_04011 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
OLEDPIAI_04012 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
OLEDPIAI_04013 3.9e-78 lrpB K transcriptional
OLEDPIAI_04014 2.4e-71 lrpA K transcriptional
OLEDPIAI_04015 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLEDPIAI_04023 1.6e-84 ydcK S Belongs to the SprT family
OLEDPIAI_04024 0.0 yhgF K COG2183 Transcriptional accessory protein
OLEDPIAI_04025 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
OLEDPIAI_04026 1.5e-82 ydcG S EVE domain
OLEDPIAI_04030 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
OLEDPIAI_04031 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLEDPIAI_04032 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OLEDPIAI_04033 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
OLEDPIAI_04034 7.1e-189 rsbU 3.1.3.3 KT phosphatase
OLEDPIAI_04035 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OLEDPIAI_04036 5.2e-57 rsbS T antagonist
OLEDPIAI_04037 1.3e-143 rsbR T Positive regulator of sigma-B
OLEDPIAI_04038 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
OLEDPIAI_04039 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OLEDPIAI_04040 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OLEDPIAI_04041 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
OLEDPIAI_04042 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OLEDPIAI_04043 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
OLEDPIAI_04044 2.2e-263 ydbT S Membrane
OLEDPIAI_04045 2.1e-82 ydbS S Bacterial PH domain
OLEDPIAI_04046 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OLEDPIAI_04047 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OLEDPIAI_04048 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OLEDPIAI_04049 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OLEDPIAI_04050 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OLEDPIAI_04051 2.2e-07 S Fur-regulated basic protein A
OLEDPIAI_04052 1.1e-18 S Fur-regulated basic protein B
OLEDPIAI_04053 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OLEDPIAI_04054 2.7e-52 ydbL
OLEDPIAI_04055 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OLEDPIAI_04056 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
OLEDPIAI_04057 4.4e-181 ydbI S AI-2E family transporter
OLEDPIAI_04058 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OLEDPIAI_04059 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
OLEDPIAI_04060 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OLEDPIAI_04061 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
OLEDPIAI_04062 3.2e-155 ydbD P Catalase
OLEDPIAI_04063 2.8e-63 ydbC S Domain of unknown function (DUF4937
OLEDPIAI_04064 8.9e-59 ydbB G Cupin domain
OLEDPIAI_04066 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
OLEDPIAI_04067 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
OLEDPIAI_04069 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
OLEDPIAI_04070 9.4e-40
OLEDPIAI_04071 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OLEDPIAI_04072 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
OLEDPIAI_04073 0.0 ydaO E amino acid
OLEDPIAI_04074 0.0 ydaN S Bacterial cellulose synthase subunit
OLEDPIAI_04075 4.5e-233 ydaM M Glycosyl transferase family group 2
OLEDPIAI_04076 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
OLEDPIAI_04077 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
OLEDPIAI_04078 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
OLEDPIAI_04079 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OLEDPIAI_04080 2.5e-74 lrpC K Transcriptional regulator
OLEDPIAI_04081 5.1e-47 ydzA EGP Major facilitator Superfamily
OLEDPIAI_04082 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
OLEDPIAI_04083 6.8e-77 ydaG 1.4.3.5 S general stress protein
OLEDPIAI_04084 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OLEDPIAI_04085 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
OLEDPIAI_04086 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLEDPIAI_04087 1.1e-99 ydaC Q Methyltransferase domain
OLEDPIAI_04088 1.4e-294 ydaB IQ acyl-CoA ligase
OLEDPIAI_04089 0.0 mtlR K transcriptional regulator, MtlR
OLEDPIAI_04090 2.8e-176 ydhF S Oxidoreductase
OLEDPIAI_04091 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
OLEDPIAI_04092 1.4e-49 yczJ S biosynthesis
OLEDPIAI_04094 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
OLEDPIAI_04095 1.2e-132 kipR K Transcriptional regulator
OLEDPIAI_04096 2.5e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
OLEDPIAI_04097 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
OLEDPIAI_04098 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
OLEDPIAI_04099 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
OLEDPIAI_04100 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
OLEDPIAI_04101 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OLEDPIAI_04103 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
OLEDPIAI_04104 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
OLEDPIAI_04105 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OLEDPIAI_04106 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OLEDPIAI_04107 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
OLEDPIAI_04108 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
OLEDPIAI_04109 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
OLEDPIAI_04110 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
OLEDPIAI_04111 7.3e-56
OLEDPIAI_04112 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
OLEDPIAI_04113 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
OLEDPIAI_04114 1.3e-100 ycnI S protein conserved in bacteria
OLEDPIAI_04115 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLEDPIAI_04116 6.1e-149 glcU U Glucose uptake
OLEDPIAI_04117 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OLEDPIAI_04118 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OLEDPIAI_04119 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLEDPIAI_04120 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
OLEDPIAI_04121 1.6e-45 ycnE S Monooxygenase
OLEDPIAI_04122 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
OLEDPIAI_04123 6.5e-154 ycnC K Transcriptional regulator
OLEDPIAI_04124 1.4e-251 ycnB EGP Major facilitator Superfamily
OLEDPIAI_04125 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
OLEDPIAI_04126 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
OLEDPIAI_04127 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_04128 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLEDPIAI_04129 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
OLEDPIAI_04132 5.2e-71 S aspartate phosphatase
OLEDPIAI_04133 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
OLEDPIAI_04134 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLEDPIAI_04135 1.7e-204 yclI V ABC transporter (permease) YclI
OLEDPIAI_04136 3.9e-122 yclH P ABC transporter
OLEDPIAI_04137 9.9e-200 gerKB F Spore germination protein
OLEDPIAI_04138 1.3e-232 gerKC S spore germination
OLEDPIAI_04139 6.8e-282 gerKA EG Spore germination protein
OLEDPIAI_04141 2.9e-310 yclG M Pectate lyase superfamily protein
OLEDPIAI_04142 1.5e-267 dtpT E amino acid peptide transporter
OLEDPIAI_04143 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
OLEDPIAI_04144 1.1e-83 yclD
OLEDPIAI_04145 4e-39 bsdD 4.1.1.61 S response to toxic substance
OLEDPIAI_04146 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
OLEDPIAI_04147 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
OLEDPIAI_04148 4.9e-162 bsdA K LysR substrate binding domain
OLEDPIAI_04149 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
OLEDPIAI_04150 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
OLEDPIAI_04151 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OLEDPIAI_04152 4.4e-115 yczE S membrane
OLEDPIAI_04153 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
OLEDPIAI_04154 4.4e-255 ycxD K GntR family transcriptional regulator
OLEDPIAI_04155 7.4e-164 ycxC EG EamA-like transporter family
OLEDPIAI_04156 4.9e-91 S YcxB-like protein
OLEDPIAI_04157 4.2e-228 EGP Major Facilitator Superfamily
OLEDPIAI_04158 5.7e-140 srfAD Q thioesterase
OLEDPIAI_04159 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
OLEDPIAI_04160 7.2e-250 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLEDPIAI_04161 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
OLEDPIAI_04162 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OLEDPIAI_04163 1.2e-84 gerD
OLEDPIAI_04164 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OLEDPIAI_04165 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OLEDPIAI_04166 9.7e-66 ybaK S Protein of unknown function (DUF2521)
OLEDPIAI_04167 8.2e-145 ybaJ Q Methyltransferase domain
OLEDPIAI_04168 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OLEDPIAI_04169 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OLEDPIAI_04170 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OLEDPIAI_04171 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OLEDPIAI_04172 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OLEDPIAI_04173 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OLEDPIAI_04174 3.6e-58 rplQ J Ribosomal protein L17
OLEDPIAI_04175 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OLEDPIAI_04176 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OLEDPIAI_04177 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OLEDPIAI_04178 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OLEDPIAI_04179 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OLEDPIAI_04180 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
OLEDPIAI_04181 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OLEDPIAI_04182 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OLEDPIAI_04183 1.8e-72 rplO J binds to the 23S rRNA
OLEDPIAI_04184 1.9e-23 rpmD J Ribosomal protein L30
OLEDPIAI_04185 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OLEDPIAI_04186 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OLEDPIAI_04187 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OLEDPIAI_04188 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OLEDPIAI_04189 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OLEDPIAI_04190 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OLEDPIAI_04191 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OLEDPIAI_04192 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OLEDPIAI_04193 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OLEDPIAI_04194 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OLEDPIAI_04195 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OLEDPIAI_04196 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OLEDPIAI_04197 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OLEDPIAI_04198 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OLEDPIAI_04199 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OLEDPIAI_04200 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OLEDPIAI_04201 3e-105 rplD J Forms part of the polypeptide exit tunnel
OLEDPIAI_04202 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OLEDPIAI_04203 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OLEDPIAI_04204 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
OLEDPIAI_04205 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OLEDPIAI_04206 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OLEDPIAI_04207 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OLEDPIAI_04208 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OLEDPIAI_04209 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
OLEDPIAI_04210 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OLEDPIAI_04211 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OLEDPIAI_04212 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
OLEDPIAI_04213 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OLEDPIAI_04214 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OLEDPIAI_04215 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OLEDPIAI_04216 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OLEDPIAI_04217 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
OLEDPIAI_04218 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OLEDPIAI_04219 4.4e-115 sigH K Belongs to the sigma-70 factor family
OLEDPIAI_04220 1.2e-88 yacP S RNA-binding protein containing a PIN domain
OLEDPIAI_04221 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OLEDPIAI_04222 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OLEDPIAI_04223 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OLEDPIAI_04224 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
OLEDPIAI_04225 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OLEDPIAI_04226 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OLEDPIAI_04227 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OLEDPIAI_04228 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
OLEDPIAI_04229 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OLEDPIAI_04230 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OLEDPIAI_04231 0.0 clpC O Belongs to the ClpA ClpB family
OLEDPIAI_04232 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OLEDPIAI_04233 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
OLEDPIAI_04234 2.9e-76 ctsR K Belongs to the CtsR family
OLEDPIAI_04235 6.8e-150 URA3 4.1.1.23 F Belongs to the OMP decarboxylase family
OLEDPIAI_04236 1.6e-160 penP 3.5.2.6 V beta-lactamase
OLEDPIAI_04237 9.6e-177 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OLEDPIAI_04238 5.4e-121 lipB 2.3.1.181 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
OLEDPIAI_04239 5.5e-272 lpdA 1.8.1.4 F Lipoamide dehydrogenase is a component of the glycine cleavage system as well as of the alpha-ketoacid dehydrogenase complexes
OLEDPIAI_04240 2.2e-300 aceF 2.3.1.12 F The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OLEDPIAI_04241 0.0 aceE 1.2.4.1 F Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OLEDPIAI_04242 2.7e-182 yaaC S YaaC-like Protein
OLEDPIAI_04243 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OLEDPIAI_04244 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OLEDPIAI_04245 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OLEDPIAI_04246 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OLEDPIAI_04247 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OLEDPIAI_04248 1.3e-09
OLEDPIAI_04249 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
OLEDPIAI_04250 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
OLEDPIAI_04251 5.6e-215 yaaH M Glycoside Hydrolase Family
OLEDPIAI_04252 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
OLEDPIAI_04253 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OLEDPIAI_04254 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OLEDPIAI_04255 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OLEDPIAI_04256 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OLEDPIAI_04257 7.9e-32 yaaL S Protein of unknown function (DUF2508)
OLEDPIAI_04258 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
OLEDPIAI_04259 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLEDPIAI_04260 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLEDPIAI_04261 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLEDPIAI_04262 1.5e-250 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLEDPIAI_04264 2e-08
OLEDPIAI_04269 6.1e-112 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLEDPIAI_04270 1.8e-44 S Major spike protein (G protein)
OLEDPIAI_04273 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)