ORF_ID e_value Gene_name EC_number CAZy COGs Description
NPGFCMHO_00001 1.5e-247 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPGFCMHO_00002 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPGFCMHO_00003 3.9e-19 yaaA S S4 domain
NPGFCMHO_00004 4.5e-208 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPGFCMHO_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPGFCMHO_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPGFCMHO_00007 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
NPGFCMHO_00008 1.7e-82 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPGFCMHO_00009 6.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPGFCMHO_00010 9.4e-156 corA P CorA-like Mg2+ transporter protein
NPGFCMHO_00011 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NPGFCMHO_00012 4.8e-76 rplI J Binds to the 23S rRNA
NPGFCMHO_00013 1.1e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NPGFCMHO_00014 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NPGFCMHO_00015 3.3e-219 I Protein of unknown function (DUF2974)
NPGFCMHO_00016 0.0
NPGFCMHO_00017 1.7e-117 yhiD S MgtC family
NPGFCMHO_00019 7.9e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NPGFCMHO_00020 1.2e-20 WQ51_00220 K Helix-turn-helix XRE-family like proteins
NPGFCMHO_00021 1.3e-85 S Protein of unknown function (DUF3278)
NPGFCMHO_00022 4.9e-201 S Aldo keto reductase
NPGFCMHO_00024 4.6e-224 S Sterol carrier protein domain
NPGFCMHO_00025 3e-116 ywnB S NAD(P)H-binding
NPGFCMHO_00026 7.1e-132 S Protein of unknown function (DUF975)
NPGFCMHO_00027 3.4e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPGFCMHO_00028 1.2e-154 yitS S EDD domain protein, DegV family
NPGFCMHO_00029 2.2e-19
NPGFCMHO_00030 0.0 tetP J elongation factor G
NPGFCMHO_00031 9.2e-167 P CorA-like Mg2+ transporter protein
NPGFCMHO_00033 2.5e-40 S Transglycosylase associated protein
NPGFCMHO_00034 6.7e-161 xth 3.1.11.2 L exodeoxyribonuclease III
NPGFCMHO_00035 0.0 L Helicase C-terminal domain protein
NPGFCMHO_00036 2.2e-165 S Alpha beta hydrolase
NPGFCMHO_00037 1.8e-40
NPGFCMHO_00038 5.5e-168 K AI-2E family transporter
NPGFCMHO_00039 3.9e-251 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NPGFCMHO_00040 6.2e-213 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPGFCMHO_00041 1.8e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
NPGFCMHO_00042 1.8e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPGFCMHO_00043 0.0 S domain, Protein
NPGFCMHO_00044 0.0 infB UW LPXTG-motif cell wall anchor domain protein
NPGFCMHO_00045 0.0 3.1.31.1 M domain protein
NPGFCMHO_00046 1.6e-266 E amino acid
NPGFCMHO_00047 1.6e-171 K LysR substrate binding domain
NPGFCMHO_00048 0.0 1.3.5.4 C FAD binding domain
NPGFCMHO_00049 1.8e-243 brnQ U Component of the transport system for branched-chain amino acids
NPGFCMHO_00050 1.8e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NPGFCMHO_00051 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NPGFCMHO_00052 1.1e-88 S Peptidase propeptide and YPEB domain
NPGFCMHO_00053 1.4e-186 cbh 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NPGFCMHO_00054 5.7e-250 yhjX_2 P Major Facilitator Superfamily
NPGFCMHO_00055 6.7e-61 yhjX_2 P Major Facilitator Superfamily
NPGFCMHO_00056 3.5e-132 yhjX_2 P Major Facilitator Superfamily
NPGFCMHO_00057 6.1e-165 arbZ I Phosphate acyltransferases
NPGFCMHO_00058 2.5e-183 arbY M Glycosyl transferase family 8
NPGFCMHO_00059 1.7e-184 arbY M Glycosyl transferase family 8
NPGFCMHO_00060 3.2e-155 arbx M Glycosyl transferase family 8
NPGFCMHO_00061 7.8e-151 arbV 2.3.1.51 I Acyl-transferase
NPGFCMHO_00064 1.2e-129 K response regulator
NPGFCMHO_00065 0.0 vicK 2.7.13.3 T Histidine kinase
NPGFCMHO_00066 3.7e-254 yycH S YycH protein
NPGFCMHO_00067 3.7e-143 yycI S YycH protein
NPGFCMHO_00068 5.1e-150 vicX 3.1.26.11 S domain protein
NPGFCMHO_00069 2.9e-184 htrA 3.4.21.107 O serine protease
NPGFCMHO_00070 9.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPGFCMHO_00071 1.1e-110 P Cobalt transport protein
NPGFCMHO_00072 9.3e-253 cbiO1 S ABC transporter, ATP-binding protein
NPGFCMHO_00073 1.3e-94 S ABC-type cobalt transport system, permease component
NPGFCMHO_00074 2.3e-170 K helix_turn_helix, arabinose operon control protein
NPGFCMHO_00075 2e-147 htpX O Belongs to the peptidase M48B family
NPGFCMHO_00076 9.9e-92 lemA S LemA family
NPGFCMHO_00077 8.3e-183 ybiR P Citrate transporter
NPGFCMHO_00078 1.3e-69 S Iron-sulphur cluster biosynthesis
NPGFCMHO_00079 1.7e-16
NPGFCMHO_00080 1.7e-154
NPGFCMHO_00082 5.5e-12 ydaM M Glycosyl transferase
NPGFCMHO_00083 3e-212 ydaM M Glycosyl transferase
NPGFCMHO_00084 2.4e-214 G Glycosyl hydrolases family 8
NPGFCMHO_00085 4.5e-120 yfbR S HD containing hydrolase-like enzyme
NPGFCMHO_00086 1.2e-160 L HNH nucleases
NPGFCMHO_00087 9.6e-138 glnQ E ABC transporter, ATP-binding protein
NPGFCMHO_00088 9.7e-281 glnP P ABC transporter permease
NPGFCMHO_00089 1.2e-106 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NPGFCMHO_00090 1.5e-64 yeaO S Protein of unknown function, DUF488
NPGFCMHO_00091 1.6e-127 terC P Integral membrane protein TerC family
NPGFCMHO_00092 5.9e-94 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
NPGFCMHO_00093 5.5e-135 cobB K SIR2 family
NPGFCMHO_00094 6.7e-81
NPGFCMHO_00095 6.4e-273 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPGFCMHO_00096 5.6e-124 yugP S Putative neutral zinc metallopeptidase
NPGFCMHO_00097 6.3e-176 S Alpha/beta hydrolase of unknown function (DUF915)
NPGFCMHO_00098 6.2e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPGFCMHO_00099 8.4e-163 ypuA S Protein of unknown function (DUF1002)
NPGFCMHO_00100 2.2e-143 2.4.1.293 GT2 M Glycosyltransferase like family 2
NPGFCMHO_00101 6.9e-124 S Alpha/beta hydrolase family
NPGFCMHO_00102 1.4e-62
NPGFCMHO_00103 4.1e-181 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPGFCMHO_00104 2.4e-220 S CAAX protease self-immunity
NPGFCMHO_00105 2.8e-241 cycA E Amino acid permease
NPGFCMHO_00106 4.2e-51 luxT K Bacterial regulatory proteins, tetR family
NPGFCMHO_00107 6.4e-38 luxT K Bacterial regulatory proteins, tetR family
NPGFCMHO_00108 1.1e-139
NPGFCMHO_00109 7.2e-286 S Cysteine-rich secretory protein family
NPGFCMHO_00110 2.8e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NPGFCMHO_00111 3.3e-95
NPGFCMHO_00112 1.5e-273 yjcE P Sodium proton antiporter
NPGFCMHO_00113 1.4e-187 yibE S overlaps another CDS with the same product name
NPGFCMHO_00114 4.9e-118 yibF S overlaps another CDS with the same product name
NPGFCMHO_00115 7.6e-157 I alpha/beta hydrolase fold
NPGFCMHO_00116 0.0 G Belongs to the glycosyl hydrolase 31 family
NPGFCMHO_00117 5.3e-130 XK27_08435 K UTRA
NPGFCMHO_00118 9.3e-217 agaS G SIS domain
NPGFCMHO_00119 1.8e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPGFCMHO_00120 8.7e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
NPGFCMHO_00121 2.9e-141 XK27_08455 G PTS system sorbose-specific iic component
NPGFCMHO_00122 5.5e-147 manZ_1 G PTS system mannose/fructose/sorbose family IID component
NPGFCMHO_00123 9.3e-68 2.7.1.191 G PTS system fructose IIA component
NPGFCMHO_00124 1.3e-18 S PD-(D/E)XK nuclease family transposase
NPGFCMHO_00125 2.3e-207 S zinc-ribbon domain
NPGFCMHO_00126 1.4e-189
NPGFCMHO_00127 3.3e-88 ntd 2.4.2.6 F Nucleoside
NPGFCMHO_00128 4.9e-99 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPGFCMHO_00129 1.5e-132 XK27_08440 K UTRA domain
NPGFCMHO_00130 2e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
NPGFCMHO_00131 3.8e-87 uspA T universal stress protein
NPGFCMHO_00133 9.8e-169 phnD P Phosphonate ABC transporter
NPGFCMHO_00134 4.3e-141 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NPGFCMHO_00135 1.6e-130 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NPGFCMHO_00136 5.4e-147 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NPGFCMHO_00137 7.3e-83
NPGFCMHO_00138 6.7e-220 S Calcineurin-like phosphoesterase
NPGFCMHO_00139 3.2e-25 S Calcineurin-like phosphoesterase
NPGFCMHO_00140 0.0 asnB 6.3.5.4 E Asparagine synthase
NPGFCMHO_00141 7.3e-266 yxbA 6.3.1.12 S ATP-grasp enzyme
NPGFCMHO_00142 1.2e-64
NPGFCMHO_00143 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NPGFCMHO_00144 5.3e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPGFCMHO_00145 6.4e-105 S Iron-sulfur cluster assembly protein
NPGFCMHO_00146 2.2e-229 XK27_04775 S PAS domain
NPGFCMHO_00147 8e-107 UW LPXTG-motif cell wall anchor domain protein
NPGFCMHO_00148 0.0 UW LPXTG-motif cell wall anchor domain protein
NPGFCMHO_00149 0.0 UW LPXTG-motif cell wall anchor domain protein
NPGFCMHO_00150 4.2e-228 yttB EGP Major facilitator Superfamily
NPGFCMHO_00151 6.6e-187 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
NPGFCMHO_00152 4.1e-173 D nuclear chromosome segregation
NPGFCMHO_00153 2e-135 rpl K Helix-turn-helix domain, rpiR family
NPGFCMHO_00154 4.3e-164 pfkB 2.7.1.11, 2.7.1.56 H pfkB family carbohydrate kinase
NPGFCMHO_00155 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPGFCMHO_00156 0.0 pepO 3.4.24.71 O Peptidase family M13
NPGFCMHO_00157 0.0 S Bacterial membrane protein, YfhO
NPGFCMHO_00158 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NPGFCMHO_00159 0.0 kup P Transport of potassium into the cell
NPGFCMHO_00160 0.0 kup P Transport of potassium into the cell
NPGFCMHO_00161 1.7e-72
NPGFCMHO_00162 2e-109
NPGFCMHO_00163 1.7e-28
NPGFCMHO_00164 1.4e-34 S Protein of unknown function (DUF2922)
NPGFCMHO_00165 3e-265 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPGFCMHO_00166 4.1e-254 lysA2 M Glycosyl hydrolases family 25
NPGFCMHO_00167 1.1e-144 fruK 2.7.1.11, 2.7.1.56 G pfkB family carbohydrate kinase
NPGFCMHO_00168 0.0 yjbQ P TrkA C-terminal domain protein
NPGFCMHO_00169 1.7e-179 S Oxidoreductase family, NAD-binding Rossmann fold
NPGFCMHO_00170 4e-131
NPGFCMHO_00171 7e-150
NPGFCMHO_00172 1.4e-74 S PAS domain
NPGFCMHO_00173 3.8e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPGFCMHO_00174 6.3e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPGFCMHO_00175 3.2e-69 2.4.1.83 GT2 S GtrA-like protein
NPGFCMHO_00176 8e-179 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NPGFCMHO_00177 9.3e-119
NPGFCMHO_00178 7.8e-152 glcU U sugar transport
NPGFCMHO_00179 9e-172 yqhA G Aldose 1-epimerase
NPGFCMHO_00180 5.6e-195 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPGFCMHO_00181 1.1e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPGFCMHO_00182 0.0 XK27_08315 M Sulfatase
NPGFCMHO_00183 2.8e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPGFCMHO_00185 3.7e-262 pepC 3.4.22.40 E aminopeptidase
NPGFCMHO_00186 8.8e-124 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPGFCMHO_00187 3.9e-256 pepC 3.4.22.40 E aminopeptidase
NPGFCMHO_00188 7.7e-43
NPGFCMHO_00189 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPGFCMHO_00190 3.3e-77 hsp O Belongs to the small heat shock protein (HSP20) family
NPGFCMHO_00191 3.4e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPGFCMHO_00192 3.7e-82
NPGFCMHO_00193 1.4e-248 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPGFCMHO_00194 1.3e-128 yydK K UTRA
NPGFCMHO_00195 3.4e-42 S Domain of unknown function (DUF3284)
NPGFCMHO_00196 8e-30 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPGFCMHO_00197 3.6e-249 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPGFCMHO_00198 1e-133 gmuR K UTRA
NPGFCMHO_00199 8.5e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
NPGFCMHO_00200 2e-52 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NPGFCMHO_00201 1.5e-269 pts23C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPGFCMHO_00202 3e-283 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPGFCMHO_00203 1.9e-158 ypbG 2.7.1.2 GK ROK family
NPGFCMHO_00204 1.3e-114
NPGFCMHO_00206 2.3e-113 E Belongs to the SOS response-associated peptidase family
NPGFCMHO_00207 2.6e-194 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPGFCMHO_00208 4.3e-91 comEB 3.5.4.12 F MafB19-like deaminase
NPGFCMHO_00209 4.7e-100 S TPM domain
NPGFCMHO_00210 1.8e-91 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NPGFCMHO_00211 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPGFCMHO_00212 1.6e-148 tatD L hydrolase, TatD family
NPGFCMHO_00213 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPGFCMHO_00214 4e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPGFCMHO_00215 7.4e-36 veg S Biofilm formation stimulator VEG
NPGFCMHO_00216 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NPGFCMHO_00217 1.1e-219 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPGFCMHO_00218 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPGFCMHO_00219 5.8e-177 yvdE K helix_turn _helix lactose operon repressor
NPGFCMHO_00220 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
NPGFCMHO_00221 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NPGFCMHO_00222 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NPGFCMHO_00223 6.9e-108 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NPGFCMHO_00224 3.6e-210 msmX P Belongs to the ABC transporter superfamily
NPGFCMHO_00225 5e-229 malE G Bacterial extracellular solute-binding protein
NPGFCMHO_00226 6.5e-254 malF P Binding-protein-dependent transport system inner membrane component
NPGFCMHO_00227 9.7e-155 malG P ABC transporter permease
NPGFCMHO_00228 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
NPGFCMHO_00229 3.3e-266 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPGFCMHO_00230 6e-73 S Domain of unknown function (DUF1934)
NPGFCMHO_00231 1.3e-64 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPGFCMHO_00232 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPGFCMHO_00233 2.2e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPGFCMHO_00234 6.6e-235 pbuX F xanthine permease
NPGFCMHO_00235 5.3e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPGFCMHO_00236 1.6e-135 K DNA-binding helix-turn-helix protein
NPGFCMHO_00237 1.6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NPGFCMHO_00239 3.5e-180 K Helix-turn-helix
NPGFCMHO_00240 4.1e-37
NPGFCMHO_00241 3.6e-67 doc S Fic/DOC family
NPGFCMHO_00242 6.5e-93 K Bacterial regulatory proteins, tetR family
NPGFCMHO_00243 1.8e-112 1.6.5.2 S Flavodoxin-like fold
NPGFCMHO_00244 5.7e-44 yjdF S Protein of unknown function (DUF2992)
NPGFCMHO_00246 7.9e-51
NPGFCMHO_00247 2.1e-50 S Domain of unknown function (DUF4160)
NPGFCMHO_00248 3.1e-58 yjdF S Protein of unknown function (DUF2992)
NPGFCMHO_00249 3.9e-98 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NPGFCMHO_00250 2.6e-94
NPGFCMHO_00251 1.8e-272 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPGFCMHO_00252 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NPGFCMHO_00253 8.6e-186 yfdV S Membrane transport protein
NPGFCMHO_00254 7.1e-40
NPGFCMHO_00255 2.4e-22 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPGFCMHO_00256 8.8e-188 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPGFCMHO_00257 4.9e-67 S Putative adhesin
NPGFCMHO_00258 9.3e-80
NPGFCMHO_00259 9.3e-08
NPGFCMHO_00260 2.6e-282 pipD E Dipeptidase
NPGFCMHO_00261 1.4e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPGFCMHO_00262 0.0 rafA 3.2.1.22 G alpha-galactosidase
NPGFCMHO_00263 1e-187 ABC-SBP S ABC transporter
NPGFCMHO_00264 4.9e-141 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NPGFCMHO_00265 6.9e-136 XK27_08845 S ABC transporter, ATP-binding protein
NPGFCMHO_00266 2.1e-283 ybeC E amino acid
NPGFCMHO_00267 8e-41 rpmE2 J Ribosomal protein L31
NPGFCMHO_00268 2.9e-262 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPGFCMHO_00269 7.7e-261 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPGFCMHO_00270 5.9e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPGFCMHO_00271 1.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPGFCMHO_00272 2.4e-124 S (CBS) domain
NPGFCMHO_00273 8.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPGFCMHO_00274 3.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPGFCMHO_00275 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPGFCMHO_00276 1.8e-34 yabO J S4 domain protein
NPGFCMHO_00277 2.3e-60 divIC D Septum formation initiator
NPGFCMHO_00278 9.9e-61 yabR J S1 RNA binding domain
NPGFCMHO_00279 2.4e-250 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPGFCMHO_00280 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPGFCMHO_00281 0.0 S membrane
NPGFCMHO_00282 4.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPGFCMHO_00283 8.9e-192 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPGFCMHO_00284 1.5e-296 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NPGFCMHO_00285 1.6e-08
NPGFCMHO_00287 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPGFCMHO_00288 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPGFCMHO_00289 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPGFCMHO_00290 4e-111 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NPGFCMHO_00291 3.5e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPGFCMHO_00292 1e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPGFCMHO_00293 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPGFCMHO_00294 5.8e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NPGFCMHO_00295 2.2e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPGFCMHO_00296 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
NPGFCMHO_00297 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPGFCMHO_00298 5.6e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPGFCMHO_00299 5e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPGFCMHO_00300 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPGFCMHO_00301 9.4e-121 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPGFCMHO_00302 6.6e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPGFCMHO_00303 2.2e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NPGFCMHO_00304 7.7e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPGFCMHO_00305 5.6e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPGFCMHO_00306 1.4e-34 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPGFCMHO_00307 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPGFCMHO_00308 2.3e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPGFCMHO_00309 2.7e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPGFCMHO_00310 5e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPGFCMHO_00311 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPGFCMHO_00312 1.9e-76 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPGFCMHO_00313 1.4e-23 rpmD J Ribosomal protein L30
NPGFCMHO_00314 1.3e-70 rplO J Binds to the 23S rRNA
NPGFCMHO_00315 2.9e-235 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPGFCMHO_00316 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPGFCMHO_00317 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPGFCMHO_00318 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NPGFCMHO_00319 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPGFCMHO_00320 2.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPGFCMHO_00321 1.3e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPGFCMHO_00322 1.3e-61 rplQ J Ribosomal protein L17
NPGFCMHO_00323 5.1e-156 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPGFCMHO_00324 2.2e-162 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPGFCMHO_00325 1.1e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPGFCMHO_00326 4.2e-152 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPGFCMHO_00327 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPGFCMHO_00328 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NPGFCMHO_00329 1.8e-80
NPGFCMHO_00330 1.2e-160 1.6.5.2 GM NmrA-like family
NPGFCMHO_00331 3.8e-110 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NPGFCMHO_00332 4.3e-129 pgm3 G Belongs to the phosphoglycerate mutase family
NPGFCMHO_00333 2.6e-52 K Transcriptional regulator, ArsR family
NPGFCMHO_00334 3.4e-155 czcD P cation diffusion facilitator family transporter
NPGFCMHO_00335 6.4e-44
NPGFCMHO_00336 5.4e-26
NPGFCMHO_00337 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPGFCMHO_00338 2.6e-185 S AAA domain
NPGFCMHO_00339 2.1e-257 pepC 3.4.22.40 E Peptidase C1-like family
NPGFCMHO_00340 3.6e-102 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NPGFCMHO_00341 1.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPGFCMHO_00342 3.1e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPGFCMHO_00343 2.6e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPGFCMHO_00344 1.7e-78 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPGFCMHO_00345 1.2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPGFCMHO_00346 8.3e-154 lacT K PRD domain
NPGFCMHO_00347 1.9e-56 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
NPGFCMHO_00348 7.5e-292 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
NPGFCMHO_00349 5.3e-291 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
NPGFCMHO_00350 1.9e-98 yvrI K sigma factor activity
NPGFCMHO_00351 1.7e-34
NPGFCMHO_00352 1.1e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NPGFCMHO_00353 3.3e-211 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NPGFCMHO_00354 2.6e-269 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPGFCMHO_00355 5.6e-228 G Major Facilitator Superfamily
NPGFCMHO_00356 6.3e-193 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPGFCMHO_00357 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPGFCMHO_00358 9.1e-12 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPGFCMHO_00359 2e-100 nusG K Participates in transcription elongation, termination and antitermination
NPGFCMHO_00360 5.3e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPGFCMHO_00361 1.6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPGFCMHO_00362 4.6e-109 glnP P ABC transporter permease
NPGFCMHO_00363 8.8e-116 glnQ 3.6.3.21 E ABC transporter
NPGFCMHO_00364 6.2e-148 aatB ET ABC transporter substrate-binding protein
NPGFCMHO_00365 3.1e-96 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPGFCMHO_00366 9.4e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPGFCMHO_00367 1.3e-149 kcsA P Ion transport protein
NPGFCMHO_00368 1.6e-32
NPGFCMHO_00369 3.9e-113 rsmC 2.1.1.172 J Methyltransferase
NPGFCMHO_00370 1.9e-23
NPGFCMHO_00371 8.4e-81 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPGFCMHO_00372 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPGFCMHO_00373 5.9e-52 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPGFCMHO_00374 6.2e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPGFCMHO_00375 2.4e-26 S Protein of unknown function (DUF2508)
NPGFCMHO_00376 3.7e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPGFCMHO_00377 4.5e-52 yaaQ S Cyclic-di-AMP receptor
NPGFCMHO_00378 2.8e-154 holB 2.7.7.7 L DNA polymerase III
NPGFCMHO_00379 1.3e-57 yabA L Involved in initiation control of chromosome replication
NPGFCMHO_00380 1.8e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPGFCMHO_00381 1.9e-127 fat 3.1.2.21 I Acyl-ACP thioesterase
NPGFCMHO_00382 8.9e-87 folT S ECF transporter, substrate-specific component
NPGFCMHO_00383 1.5e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NPGFCMHO_00384 2.4e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NPGFCMHO_00385 5.6e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPGFCMHO_00386 4.3e-09 D nuclear chromosome segregation
NPGFCMHO_00387 8.4e-10 D nuclear chromosome segregation
NPGFCMHO_00388 1.3e-170
NPGFCMHO_00389 4.2e-115
NPGFCMHO_00390 1e-240 clcA P chloride
NPGFCMHO_00391 4.5e-48
NPGFCMHO_00392 2.1e-99 S Protein of unknown function (DUF3990)
NPGFCMHO_00393 1.4e-189 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPGFCMHO_00394 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPGFCMHO_00395 1.3e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPGFCMHO_00396 2.3e-78 apfA 2.7.7.72, 3.6.1.61 F NUDIX domain
NPGFCMHO_00397 1.2e-48 L bacterial-type proximal promoter sequence-specific DNA binding
NPGFCMHO_00398 1.7e-53 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NPGFCMHO_00399 5e-234 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPGFCMHO_00400 6.7e-153 K helix_turn_helix, arabinose operon control protein
NPGFCMHO_00401 0.0 bglX 3.2.1.21 GH3 G hydrolase, family 3
NPGFCMHO_00402 0.0 scrA 2.7.1.211 G phosphotransferase system
NPGFCMHO_00403 2.2e-306 scrB 2.7.1.211, 3.2.1.26 GH32 G Glycosyl hydrolases family 32
NPGFCMHO_00404 9.3e-155 K Helix-turn-helix XRE-family like proteins
NPGFCMHO_00405 8.3e-68
NPGFCMHO_00406 0.0 uup S ABC transporter, ATP-binding protein
NPGFCMHO_00407 8.7e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPGFCMHO_00408 3e-104 yvdD 3.2.2.10 S Belongs to the LOG family
NPGFCMHO_00409 1e-78 XK27_02470 K LytTr DNA-binding domain
NPGFCMHO_00410 1.7e-123 liaI S membrane
NPGFCMHO_00411 8.8e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPGFCMHO_00412 8.2e-296 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPGFCMHO_00413 0.0 fhaB 4.3.1.7 UW LPXTG-motif cell wall anchor domain protein
NPGFCMHO_00414 0.0 nisT V ABC transporter
NPGFCMHO_00415 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPGFCMHO_00416 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPGFCMHO_00417 1.6e-100 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPGFCMHO_00418 3.9e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPGFCMHO_00419 4.5e-31 yajC U Preprotein translocase
NPGFCMHO_00420 1.1e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPGFCMHO_00421 1.4e-209 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPGFCMHO_00422 6.6e-184 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NPGFCMHO_00423 1.5e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPGFCMHO_00424 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPGFCMHO_00425 2.6e-42 yrzL S Belongs to the UPF0297 family
NPGFCMHO_00426 1.4e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPGFCMHO_00427 1.8e-50 yrzB S Belongs to the UPF0473 family
NPGFCMHO_00428 1.6e-91 cvpA S Colicin V production protein
NPGFCMHO_00429 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPGFCMHO_00430 6.6e-53 trxA O Belongs to the thioredoxin family
NPGFCMHO_00431 2.4e-68 yslB S Protein of unknown function (DUF2507)
NPGFCMHO_00432 6.5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NPGFCMHO_00433 2.2e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPGFCMHO_00434 9.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPGFCMHO_00435 2e-158 ykuT M mechanosensitive ion channel
NPGFCMHO_00437 4e-51
NPGFCMHO_00438 5.9e-213 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NPGFCMHO_00439 4.3e-178 ccpA K catabolite control protein A
NPGFCMHO_00440 1.9e-300 V ABC transporter transmembrane region
NPGFCMHO_00441 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
NPGFCMHO_00442 2.4e-275 pepV 3.5.1.18 E dipeptidase PepV
NPGFCMHO_00443 8e-268 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPGFCMHO_00444 2e-55
NPGFCMHO_00445 3.6e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPGFCMHO_00446 9.1e-98 yutD S Protein of unknown function (DUF1027)
NPGFCMHO_00447 3.6e-148 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPGFCMHO_00448 8.6e-105 S Protein of unknown function (DUF1461)
NPGFCMHO_00449 2.7e-117 dedA S SNARE-like domain protein
NPGFCMHO_00450 4.8e-179 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NPGFCMHO_00451 6e-61 yugI 5.3.1.9 J general stress protein
NPGFCMHO_00456 9.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPGFCMHO_00457 3.2e-259 qacA EGP Major facilitator Superfamily
NPGFCMHO_00458 5.5e-118 3.6.1.27 I Acid phosphatase homologues
NPGFCMHO_00459 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPGFCMHO_00460 7.1e-303 ytgP S Polysaccharide biosynthesis protein
NPGFCMHO_00461 2.2e-218 I Protein of unknown function (DUF2974)
NPGFCMHO_00462 8e-121
NPGFCMHO_00463 3.8e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPGFCMHO_00464 8.3e-125 M ErfK YbiS YcfS YnhG
NPGFCMHO_00465 3.3e-172 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPGFCMHO_00466 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NPGFCMHO_00467 6.5e-173 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NPGFCMHO_00468 2.4e-50
NPGFCMHO_00469 6.9e-77 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
NPGFCMHO_00470 1.2e-57 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NPGFCMHO_00472 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPGFCMHO_00473 2.5e-129 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
NPGFCMHO_00474 2.2e-111 ylbE GM NAD(P)H-binding
NPGFCMHO_00475 1.8e-83 yebR 1.8.4.14 T GAF domain-containing protein
NPGFCMHO_00476 3.2e-194 S Bacteriocin helveticin-J
NPGFCMHO_00477 9.6e-106 tag 3.2.2.20 L glycosylase
NPGFCMHO_00478 7.9e-166 mleP3 S Membrane transport protein
NPGFCMHO_00479 6.8e-139 S CAAX amino terminal protease
NPGFCMHO_00480 1.4e-144 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NPGFCMHO_00481 1.5e-256 emrY EGP Major facilitator Superfamily
NPGFCMHO_00482 4e-262 emrY EGP Major facilitator Superfamily
NPGFCMHO_00483 4.4e-94 yxdD K Bacterial regulatory proteins, tetR family
NPGFCMHO_00484 0.0 4.2.1.53 S Myosin-crossreactive antigen
NPGFCMHO_00485 1.4e-77 2.3.1.128 K acetyltransferase
NPGFCMHO_00486 1.7e-145 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NPGFCMHO_00487 3.2e-103 yagU S Protein of unknown function (DUF1440)
NPGFCMHO_00488 4.7e-151 S hydrolase
NPGFCMHO_00489 8e-75 K Transcriptional regulator
NPGFCMHO_00490 2.9e-62 K Transcriptional regulator
NPGFCMHO_00491 5.6e-242 pyrP F Permease
NPGFCMHO_00492 1.3e-137 lacR K DeoR C terminal sensor domain
NPGFCMHO_00493 4.7e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
NPGFCMHO_00494 1.9e-106 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
NPGFCMHO_00495 1.6e-128 S Domain of unknown function (DUF4867)
NPGFCMHO_00496 7.2e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPGFCMHO_00497 6.3e-51 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
NPGFCMHO_00498 2.8e-268 gatC G PTS system sugar-specific permease component
NPGFCMHO_00499 1.3e-38
NPGFCMHO_00500 2e-152 lacT K CAT RNA binding domain
NPGFCMHO_00501 8.7e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
NPGFCMHO_00502 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
NPGFCMHO_00503 5.7e-293 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
NPGFCMHO_00504 1e-201 S PFAM Archaeal ATPase
NPGFCMHO_00505 8.2e-165 K LysR family
NPGFCMHO_00506 0.0 1.3.5.4 C FMN_bind
NPGFCMHO_00507 3.7e-260 P Sodium:sulfate symporter transmembrane region
NPGFCMHO_00508 5.7e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
NPGFCMHO_00509 3.3e-112 3.6.1.27 I Acid phosphatase homologues
NPGFCMHO_00510 8.7e-218 mdtG EGP Major facilitator Superfamily
NPGFCMHO_00511 1.5e-32
NPGFCMHO_00512 6.1e-73 K helix_turn_helix multiple antibiotic resistance protein
NPGFCMHO_00513 5.8e-82
NPGFCMHO_00514 2.7e-210 pepA E M42 glutamyl aminopeptidase
NPGFCMHO_00516 5.9e-88 2.7.1.191 G PTS system sorbose subfamily IIB component
NPGFCMHO_00517 1.2e-103 G PTS system sorbose-specific iic component
NPGFCMHO_00518 3.4e-152 G PTS system mannose/fructose/sorbose family IID component
NPGFCMHO_00519 6.8e-72 2.7.1.191 G PTS system fructose IIA component
NPGFCMHO_00520 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NPGFCMHO_00521 8.2e-182 lacI3 K helix_turn _helix lactose operon repressor
NPGFCMHO_00522 0.0 3.2.1.177 GH31 G Glycosyl hydrolases family 31
NPGFCMHO_00523 1.6e-266 dtpT U amino acid peptide transporter
NPGFCMHO_00524 2.9e-208 naiP EGP Major facilitator Superfamily
NPGFCMHO_00525 2.5e-155 S Alpha beta hydrolase
NPGFCMHO_00526 4.6e-76 K Transcriptional regulator, MarR family
NPGFCMHO_00527 0.0 XK27_09600 V ABC transporter, ATP-binding protein
NPGFCMHO_00528 0.0 V ABC transporter transmembrane region
NPGFCMHO_00529 1.3e-148 glnH ET ABC transporter
NPGFCMHO_00530 2.7e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPGFCMHO_00531 9.1e-150 glnH ET ABC transporter
NPGFCMHO_00532 3.2e-110 gluC P ABC transporter permease
NPGFCMHO_00533 2e-107 glnP P ABC transporter permease
NPGFCMHO_00534 1.3e-156 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPGFCMHO_00535 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NPGFCMHO_00536 1.1e-130 treR K UTRA
NPGFCMHO_00537 0.0 treB 2.7.1.211 G phosphotransferase system
NPGFCMHO_00538 8.3e-84 S Putative adhesin
NPGFCMHO_00539 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
NPGFCMHO_00540 2.6e-158 EGP Major facilitator superfamily
NPGFCMHO_00541 1.3e-76 EGP Major facilitator superfamily
NPGFCMHO_00543 6.8e-56 S Enterocin A Immunity
NPGFCMHO_00544 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
NPGFCMHO_00545 4.3e-163 rssA S Phospholipase, patatin family
NPGFCMHO_00546 1.1e-257 glnPH2 P ABC transporter permease
NPGFCMHO_00547 1.7e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPGFCMHO_00548 6.2e-96 K Acetyltransferase (GNAT) domain
NPGFCMHO_00549 3.5e-160 pstS P Phosphate
NPGFCMHO_00550 2.1e-161 pstC P probably responsible for the translocation of the substrate across the membrane
NPGFCMHO_00551 8.3e-157 pstA P Phosphate transport system permease protein PstA
NPGFCMHO_00552 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPGFCMHO_00553 2.7e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPGFCMHO_00554 2.6e-118 phoU P Plays a role in the regulation of phosphate uptake
NPGFCMHO_00555 7.5e-283 S C4-dicarboxylate anaerobic carrier
NPGFCMHO_00556 5.8e-85 dps P Belongs to the Dps family
NPGFCMHO_00558 3.2e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPGFCMHO_00559 4.8e-128 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NPGFCMHO_00560 4.1e-175 rihB 3.2.2.1 F Nucleoside
NPGFCMHO_00561 4e-133 gntR K UbiC transcription regulator-associated domain protein
NPGFCMHO_00562 2e-52 S Enterocin A Immunity
NPGFCMHO_00563 8.9e-139 glcR K DeoR C terminal sensor domain
NPGFCMHO_00564 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NPGFCMHO_00565 1.6e-120 C nitroreductase
NPGFCMHO_00566 7.2e-132
NPGFCMHO_00567 1.6e-252 yhdP S Transporter associated domain
NPGFCMHO_00568 5.7e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPGFCMHO_00569 2.9e-235 potE E amino acid
NPGFCMHO_00570 2.6e-137 M Glycosyl hydrolases family 25
NPGFCMHO_00571 1.9e-207 yfmL 3.6.4.13 L DEAD DEAH box helicase
NPGFCMHO_00572 8.6e-251 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPGFCMHO_00575 3.1e-217 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPGFCMHO_00576 8e-88 gtcA S Teichoic acid glycosylation protein
NPGFCMHO_00577 8.5e-78 fld C Flavodoxin
NPGFCMHO_00578 6.7e-161 map 3.4.11.18 E Methionine Aminopeptidase
NPGFCMHO_00579 1.6e-166 yihY S Belongs to the UPF0761 family
NPGFCMHO_00580 2.3e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPGFCMHO_00581 2.5e-155 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPGFCMHO_00582 1.2e-180 E ABC transporter, ATP-binding protein
NPGFCMHO_00583 1.6e-288 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NPGFCMHO_00584 1.9e-68 O OsmC-like protein
NPGFCMHO_00585 7.1e-20 ltrA S Bacterial low temperature requirement A protein (LtrA)
NPGFCMHO_00586 9.2e-115 2.7.6.5 T Region found in RelA / SpoT proteins
NPGFCMHO_00587 2.4e-116 K response regulator
NPGFCMHO_00588 1.2e-233 sptS 2.7.13.3 T Histidine kinase
NPGFCMHO_00589 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NPGFCMHO_00590 2.4e-56
NPGFCMHO_00591 2.8e-58
NPGFCMHO_00592 0.0 pepN 3.4.11.2 E aminopeptidase
NPGFCMHO_00593 3.4e-143 S haloacid dehalogenase-like hydrolase
NPGFCMHO_00594 1.8e-122 S CAAX protease self-immunity
NPGFCMHO_00596 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPGFCMHO_00597 6.6e-72
NPGFCMHO_00598 9.6e-109 fic D Fic/DOC family
NPGFCMHO_00599 6.2e-226 I transferase activity, transferring acyl groups other than amino-acyl groups
NPGFCMHO_00600 3.5e-128 pnb C nitroreductase
NPGFCMHO_00601 1.1e-98 S Domain of unknown function (DUF4811)
NPGFCMHO_00602 3.6e-266 lmrB EGP Major facilitator Superfamily
NPGFCMHO_00603 4.2e-77 K MerR HTH family regulatory protein
NPGFCMHO_00604 0.0 oppA E ABC transporter substrate-binding protein
NPGFCMHO_00605 4.6e-61 pdxH S Pyridoxamine 5'-phosphate oxidase
NPGFCMHO_00606 4.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
NPGFCMHO_00607 7.3e-169 2.7.1.2 GK ROK family
NPGFCMHO_00608 3.6e-165 rhaS6 K helix_turn_helix, arabinose operon control protein
NPGFCMHO_00609 9.5e-177 I Carboxylesterase family
NPGFCMHO_00610 1.1e-191 yhjX P Major Facilitator Superfamily
NPGFCMHO_00611 2.5e-306 S Predicted membrane protein (DUF2207)
NPGFCMHO_00612 5.2e-56 K Acetyltransferase (GNAT) domain
NPGFCMHO_00613 1.4e-59
NPGFCMHO_00614 1.7e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NPGFCMHO_00615 1.2e-92 S ECF-type riboflavin transporter, S component
NPGFCMHO_00616 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NPGFCMHO_00617 1.2e-12
NPGFCMHO_00618 4.4e-247 S Uncharacterized protein conserved in bacteria (DUF2325)
NPGFCMHO_00619 1.2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPGFCMHO_00620 7.3e-64 arsC 1.20.4.1 P Belongs to the ArsC family
NPGFCMHO_00621 2e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NPGFCMHO_00622 2.8e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NPGFCMHO_00623 2e-197 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NPGFCMHO_00624 8.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPGFCMHO_00625 2.2e-73 yqhY S Asp23 family, cell envelope-related function
NPGFCMHO_00626 8e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPGFCMHO_00627 2.1e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPGFCMHO_00628 1.5e-253 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPGFCMHO_00629 3.8e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPGFCMHO_00630 7.8e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPGFCMHO_00631 3.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NPGFCMHO_00632 2e-265 recN L May be involved in recombinational repair of damaged DNA
NPGFCMHO_00633 4.6e-48
NPGFCMHO_00634 1.6e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NPGFCMHO_00635 1.7e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPGFCMHO_00636 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPGFCMHO_00637 7.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPGFCMHO_00638 1.2e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPGFCMHO_00639 4.5e-140 stp 3.1.3.16 T phosphatase
NPGFCMHO_00640 0.0 KLT serine threonine protein kinase
NPGFCMHO_00641 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPGFCMHO_00642 1.8e-121 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NPGFCMHO_00643 1e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
NPGFCMHO_00644 1.6e-25 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NPGFCMHO_00645 1.4e-57 asp S Asp23 family, cell envelope-related function
NPGFCMHO_00646 9.6e-308 yloV S DAK2 domain fusion protein YloV
NPGFCMHO_00647 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPGFCMHO_00648 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPGFCMHO_00649 2.6e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPGFCMHO_00650 1.1e-192 oppD P Belongs to the ABC transporter superfamily
NPGFCMHO_00651 4.4e-180 oppF P Belongs to the ABC transporter superfamily
NPGFCMHO_00652 7.5e-180 oppB P ABC transporter permease
NPGFCMHO_00653 2.1e-163 oppC P Binding-protein-dependent transport system inner membrane component
NPGFCMHO_00654 0.0 oppA E ABC transporter substrate-binding protein
NPGFCMHO_00655 0.0 oppA E ABC transporter substrate-binding protein
NPGFCMHO_00656 1.6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPGFCMHO_00657 0.0 smc D Required for chromosome condensation and partitioning
NPGFCMHO_00658 7.8e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPGFCMHO_00659 1.6e-287 pipD E Dipeptidase
NPGFCMHO_00660 4.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPGFCMHO_00661 1.4e-227 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPGFCMHO_00662 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NPGFCMHO_00663 7.4e-97 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPGFCMHO_00664 2.2e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NPGFCMHO_00665 1e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPGFCMHO_00666 9.3e-118 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NPGFCMHO_00667 6.5e-75 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NPGFCMHO_00668 1.1e-115 ung2 3.2.2.27 L Uracil-DNA glycosylase
NPGFCMHO_00669 7.9e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPGFCMHO_00670 1.5e-34 ynzC S UPF0291 protein
NPGFCMHO_00671 1.5e-30 yneF S Uncharacterised protein family (UPF0154)
NPGFCMHO_00672 0.0 mdlA V ABC transporter
NPGFCMHO_00673 6.1e-300 mdlB V ABC transporter
NPGFCMHO_00674 7.2e-225 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NPGFCMHO_00675 9.8e-117 plsC 2.3.1.51 I Acyltransferase
NPGFCMHO_00676 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
NPGFCMHO_00677 9.6e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
NPGFCMHO_00678 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPGFCMHO_00679 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NPGFCMHO_00680 3.4e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPGFCMHO_00681 1.4e-135 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPGFCMHO_00682 3.4e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NPGFCMHO_00683 1.2e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NPGFCMHO_00684 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPGFCMHO_00685 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPGFCMHO_00686 4.7e-82 rimP J Required for maturation of 30S ribosomal subunits
NPGFCMHO_00687 1.1e-217 nusA K Participates in both transcription termination and antitermination
NPGFCMHO_00688 2e-46 ylxR K Protein of unknown function (DUF448)
NPGFCMHO_00689 6e-46 rplGA J ribosomal protein
NPGFCMHO_00690 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPGFCMHO_00691 7.9e-61 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPGFCMHO_00692 1.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPGFCMHO_00693 7.6e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NPGFCMHO_00694 1.6e-282 lsa S ABC transporter
NPGFCMHO_00695 6.7e-121 S GyrI-like small molecule binding domain
NPGFCMHO_00696 2.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPGFCMHO_00697 8.5e-78 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPGFCMHO_00698 0.0 dnaK O Heat shock 70 kDa protein
NPGFCMHO_00699 1.6e-171 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPGFCMHO_00700 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPGFCMHO_00701 9.3e-124 srtA 3.4.22.70 M sortase family
NPGFCMHO_00702 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NPGFCMHO_00703 1.3e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPGFCMHO_00704 1.2e-171 S Phage integrase family
NPGFCMHO_00705 7e-31 M Host cell surface-exposed lipoprotein
NPGFCMHO_00706 5.9e-57 S Membrane
NPGFCMHO_00707 1.1e-122 V Abi-like protein
NPGFCMHO_00708 6.7e-31 S Short C-terminal domain
NPGFCMHO_00709 8.2e-16 S Pfam:Peptidase_M78
NPGFCMHO_00710 7.3e-27 ps115 K sequence-specific DNA binding
NPGFCMHO_00711 6.4e-11
NPGFCMHO_00712 6e-24 S Uncharacterized protein conserved in bacteria (DUF2188)
NPGFCMHO_00713 3.6e-28 K Cro/C1-type HTH DNA-binding domain
NPGFCMHO_00716 8.4e-43 K Phage regulatory protein
NPGFCMHO_00717 1.3e-27
NPGFCMHO_00718 1.4e-33
NPGFCMHO_00719 1.6e-12
NPGFCMHO_00723 2.4e-82 S AAA domain
NPGFCMHO_00725 2.2e-160 S helicase activity
NPGFCMHO_00726 9.7e-27 S Protein of unknown function (DUF669)
NPGFCMHO_00728 1.2e-263 S Phage plasmid primase, P4
NPGFCMHO_00731 1.3e-08
NPGFCMHO_00732 6e-23
NPGFCMHO_00735 9.3e-21
NPGFCMHO_00741 2.3e-31 S VRR_NUC
NPGFCMHO_00743 2.1e-74 arpU S Phage transcriptional regulator, ArpU family
NPGFCMHO_00744 4.7e-117 xtmA L Terminase small subunit
NPGFCMHO_00745 1.8e-237 S Terminase-like family
NPGFCMHO_00746 1.8e-268 S Phage portal protein, SPP1 Gp6-like
NPGFCMHO_00747 3.7e-39 S Cysteine protease Prp
NPGFCMHO_00748 3.2e-195 S Phage Mu protein F like protein
NPGFCMHO_00749 2.8e-98 S Domain of unknown function (DUF4355)
NPGFCMHO_00750 5.3e-49
NPGFCMHO_00751 3.7e-180 S Phage major capsid protein E
NPGFCMHO_00752 5.6e-36
NPGFCMHO_00753 2.4e-51
NPGFCMHO_00754 2.2e-83
NPGFCMHO_00755 1.5e-51
NPGFCMHO_00756 8.8e-68 S Phage tail tube protein, TTP
NPGFCMHO_00757 1.4e-61
NPGFCMHO_00758 1.2e-37
NPGFCMHO_00759 0.0 M Phage tail tape measure protein TP901
NPGFCMHO_00760 1.4e-59
NPGFCMHO_00761 6.4e-275 GT2,GT4 LM gp58-like protein
NPGFCMHO_00763 2.9e-33
NPGFCMHO_00764 1.9e-20
NPGFCMHO_00767 1e-157 S peptidoglycan catabolic process
NPGFCMHO_00769 1.9e-07
NPGFCMHO_00770 1.9e-278 yjeM E Amino Acid
NPGFCMHO_00771 9.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPGFCMHO_00772 9.4e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPGFCMHO_00773 1.6e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPGFCMHO_00774 1.1e-250 G Major Facilitator
NPGFCMHO_00775 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
NPGFCMHO_00776 1.4e-158 lysR5 K LysR substrate binding domain
NPGFCMHO_00778 2.2e-102 3.6.1.27 I Acid phosphatase homologues
NPGFCMHO_00779 1.6e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPGFCMHO_00780 3.7e-18 S Sugar efflux transporter for intercellular exchange
NPGFCMHO_00781 1.1e-310 ybiT S ABC transporter, ATP-binding protein
NPGFCMHO_00782 9.2e-42 K Helix-turn-helix domain
NPGFCMHO_00783 2.8e-146 F DNA/RNA non-specific endonuclease
NPGFCMHO_00784 1.5e-60 L nuclease
NPGFCMHO_00785 1.8e-156 metQ1 P Belongs to the nlpA lipoprotein family
NPGFCMHO_00786 1.6e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPGFCMHO_00787 2.8e-67 metI P ABC transporter permease
NPGFCMHO_00788 3.8e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPGFCMHO_00789 7.2e-261 frdC 1.3.5.4 C FAD binding domain
NPGFCMHO_00790 2.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPGFCMHO_00791 2.2e-257 yjjP S Putative threonine/serine exporter
NPGFCMHO_00792 2.5e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
NPGFCMHO_00793 0.0 aha1 P E1-E2 ATPase
NPGFCMHO_00794 0.0 S Bacterial membrane protein, YfhO
NPGFCMHO_00795 3e-87 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPGFCMHO_00796 4.6e-174 prmA J Ribosomal protein L11 methyltransferase
NPGFCMHO_00797 1.4e-65
NPGFCMHO_00798 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPGFCMHO_00799 7.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPGFCMHO_00800 1.1e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NPGFCMHO_00801 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NPGFCMHO_00802 3.1e-73
NPGFCMHO_00803 1.5e-82 mutT 3.6.1.55 F NUDIX domain
NPGFCMHO_00804 5.8e-35
NPGFCMHO_00805 7.2e-68
NPGFCMHO_00806 1.6e-64 S Domain of unknown function DUF1828
NPGFCMHO_00807 7.4e-88 S Rib/alpha-like repeat
NPGFCMHO_00808 7.7e-247 yagE E amino acid
NPGFCMHO_00809 5.1e-116 GM NmrA-like family
NPGFCMHO_00810 1.9e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
NPGFCMHO_00811 1.8e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
NPGFCMHO_00812 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPGFCMHO_00813 3.5e-241 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPGFCMHO_00814 0.0 oatA I Acyltransferase
NPGFCMHO_00815 1.4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPGFCMHO_00816 9.3e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPGFCMHO_00817 7.5e-47 yrvD S Lipopolysaccharide assembly protein A domain
NPGFCMHO_00818 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NPGFCMHO_00819 4.3e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NPGFCMHO_00820 2.1e-28 S Protein of unknown function (DUF2929)
NPGFCMHO_00821 0.0 dnaE 2.7.7.7 L DNA polymerase
NPGFCMHO_00823 2.7e-182 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPGFCMHO_00824 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NPGFCMHO_00825 1.5e-166 cvfB S S1 domain
NPGFCMHO_00826 2.5e-169 xerD D recombinase XerD
NPGFCMHO_00827 3.1e-62 ribT K acetyltransferase
NPGFCMHO_00828 1.1e-135 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPGFCMHO_00829 2.9e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPGFCMHO_00830 1.8e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPGFCMHO_00831 1.9e-58 M Lysin motif
NPGFCMHO_00832 3.4e-98 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPGFCMHO_00833 1.4e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NPGFCMHO_00834 2.3e-218 rpsA 1.17.7.4 J Ribosomal protein S1
NPGFCMHO_00835 1e-240 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NPGFCMHO_00836 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPGFCMHO_00837 1.1e-231 S Tetratricopeptide repeat protein
NPGFCMHO_00838 0.0 KL domain protein
NPGFCMHO_00839 2.6e-134
NPGFCMHO_00840 1.8e-292 hsdM 2.1.1.72 V type I restriction-modification system
NPGFCMHO_00841 1.6e-224 3.1.21.3 V Type I restriction modification DNA specificity domain
NPGFCMHO_00842 2.4e-178 L Belongs to the 'phage' integrase family
NPGFCMHO_00843 8.7e-209 3.1.21.3 V Type I restriction modification DNA specificity domain
NPGFCMHO_00844 0.0 hsdR 3.1.21.3 V EcoEI R protein C-terminal
NPGFCMHO_00845 0.0 S Protein of unknown function DUF262
NPGFCMHO_00846 5.8e-76 1.3.5.4 C FMN_bind
NPGFCMHO_00847 4.2e-261 1.3.5.4 C FMN_bind
NPGFCMHO_00848 7.2e-92
NPGFCMHO_00849 9.2e-109
NPGFCMHO_00850 3.8e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPGFCMHO_00851 6e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPGFCMHO_00852 2.6e-115 hlyIII S protein, hemolysin III
NPGFCMHO_00853 2.6e-152 DegV S Uncharacterised protein, DegV family COG1307
NPGFCMHO_00854 9.2e-36 yozE S Belongs to the UPF0346 family
NPGFCMHO_00855 1.3e-265 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NPGFCMHO_00856 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPGFCMHO_00857 9.8e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPGFCMHO_00858 6.6e-156 dprA LU DNA protecting protein DprA
NPGFCMHO_00859 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPGFCMHO_00860 3e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPGFCMHO_00861 2.5e-172 xerC D Phage integrase, N-terminal SAM-like domain
NPGFCMHO_00862 9.7e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPGFCMHO_00863 8.2e-252 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPGFCMHO_00864 5.3e-180 lacX 5.1.3.3 G Aldose 1-epimerase
NPGFCMHO_00865 1.1e-104 K LysR substrate binding domain
NPGFCMHO_00866 3.4e-100 S LexA-binding, inner membrane-associated putative hydrolase
NPGFCMHO_00868 3.5e-66
NPGFCMHO_00869 1.1e-179 MA20_14895 S Conserved hypothetical protein 698
NPGFCMHO_00870 1.1e-71 K Transcriptional regulator
NPGFCMHO_00871 5.6e-52
NPGFCMHO_00872 1.1e-42
NPGFCMHO_00873 1.8e-41 K peptidyl-tyrosine sulfation
NPGFCMHO_00874 6.6e-124 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPGFCMHO_00875 2e-112 ybbL S ABC transporter, ATP-binding protein
NPGFCMHO_00876 7.9e-132 ybbM S Uncharacterised protein family (UPF0014)
NPGFCMHO_00877 3e-98 K Acetyltransferase (GNAT) domain
NPGFCMHO_00878 2.8e-51 S Protein of unknown function (DUF3021)
NPGFCMHO_00879 1.3e-75 K LytTr DNA-binding domain
NPGFCMHO_00880 7.9e-107 S Protein of unknown function (DUF1211)
NPGFCMHO_00881 0.0 S domain, Protein
NPGFCMHO_00883 0.0 bamA UW LPXTG-motif cell wall anchor domain protein
NPGFCMHO_00884 0.0 M domain protein
NPGFCMHO_00886 5.7e-302
NPGFCMHO_00887 6e-111 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPGFCMHO_00888 7.4e-120 3.6.1.55 F NUDIX domain
NPGFCMHO_00889 4.4e-71 S Putative adhesin
NPGFCMHO_00890 2.2e-249 brnQ U Component of the transport system for branched-chain amino acids
NPGFCMHO_00891 4.7e-12 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPGFCMHO_00892 5.9e-17 L Plasmid pRiA4b ORF-3-like protein
NPGFCMHO_00893 5.2e-68 K HxlR family
NPGFCMHO_00894 2.7e-48
NPGFCMHO_00895 5.1e-231 4.2.1.6, 5.1.2.2 M Mandelate racemase muconate lactonizing enzyme
NPGFCMHO_00896 2.5e-11 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
NPGFCMHO_00897 3e-76 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
NPGFCMHO_00898 3.2e-292 P ABC transporter
NPGFCMHO_00899 7.3e-13 V ABC-type multidrug transport system, ATPase and permease components
NPGFCMHO_00900 6.3e-260 V ABC-type multidrug transport system, ATPase and permease components
NPGFCMHO_00901 1.2e-41 yphH S Cupin domain
NPGFCMHO_00902 1.4e-189 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPGFCMHO_00903 4.4e-35 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
NPGFCMHO_00904 1.7e-32 mta K helix_turn_helix, mercury resistance
NPGFCMHO_00905 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NPGFCMHO_00906 2.5e-125 lmrA 3.6.3.44 V ABC transporter
NPGFCMHO_00907 3.8e-156 C Aldo keto reductase
NPGFCMHO_00909 9.2e-101 K Transcriptional regulator C-terminal region
NPGFCMHO_00910 1.7e-231 E Alpha/beta hydrolase of unknown function (DUF1100)
NPGFCMHO_00911 2.1e-117 GM NAD(P)H-binding
NPGFCMHO_00912 1.7e-216 mdt(A) EGP Major facilitator Superfamily
NPGFCMHO_00913 2.2e-61 S Sulfite exporter TauE/SafE
NPGFCMHO_00914 1.9e-32 G Major facilitator Superfamily
NPGFCMHO_00915 2.2e-243 npr 1.11.1.1 C NADH oxidase
NPGFCMHO_00916 2.3e-63 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NPGFCMHO_00917 4.1e-30 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NPGFCMHO_00918 3e-173 yobV1 K WYL domain
NPGFCMHO_00919 2.4e-68 S pyridoxamine 5-phosphate
NPGFCMHO_00920 5.5e-50 K LytTr DNA-binding domain
NPGFCMHO_00921 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NPGFCMHO_00922 4.6e-35 copZ C Heavy-metal-associated domain
NPGFCMHO_00923 1.4e-93 dps P Belongs to the Dps family
NPGFCMHO_00924 1.5e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NPGFCMHO_00925 2.1e-96 K Acetyltransferase (GNAT) family
NPGFCMHO_00926 6.9e-80 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NPGFCMHO_00927 5.5e-50 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NPGFCMHO_00928 6.2e-76 K Transcriptional regulator
NPGFCMHO_00929 7.9e-69 ogt 2.1.1.63 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NPGFCMHO_00930 2.5e-86 XK27_09675 K Acetyltransferase (GNAT) domain
NPGFCMHO_00931 1e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NPGFCMHO_00932 1.5e-11 yrvN L AAA C-terminal domain
NPGFCMHO_00933 5.4e-203 yrvN L AAA C-terminal domain
NPGFCMHO_00934 3e-34 4.1.1.45 S Amidohydrolase
NPGFCMHO_00935 2.3e-105 4.1.1.45 S Amidohydrolase
NPGFCMHO_00936 9e-122 ybhL S Belongs to the BI1 family
NPGFCMHO_00937 2.9e-14 C Aldo/keto reductase family
NPGFCMHO_00938 1.1e-74 C Aldo/keto reductase family
NPGFCMHO_00939 5.1e-167 akr5f 1.1.1.346 S reductase
NPGFCMHO_00940 1.8e-124 magIII L Base excision DNA repair protein, HhH-GPD family
NPGFCMHO_00941 2.6e-109 lacA 2.3.1.79 S Transferase hexapeptide repeat
NPGFCMHO_00942 8.9e-116 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPGFCMHO_00943 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPGFCMHO_00944 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPGFCMHO_00945 2.2e-179 K Transcriptional regulator
NPGFCMHO_00946 2.8e-171 ppaC 3.6.1.1 C inorganic pyrophosphatase
NPGFCMHO_00947 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NPGFCMHO_00948 7.7e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPGFCMHO_00949 1.5e-124 yoaK S Protein of unknown function (DUF1275)
NPGFCMHO_00950 4.9e-204 xerS L Belongs to the 'phage' integrase family
NPGFCMHO_00951 6.7e-167 K Transcriptional regulator
NPGFCMHO_00952 3.7e-151
NPGFCMHO_00953 2e-163 degV S EDD domain protein, DegV family
NPGFCMHO_00954 3.8e-64
NPGFCMHO_00955 0.0 FbpA K Fibronectin-binding protein
NPGFCMHO_00956 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
NPGFCMHO_00957 3.3e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPGFCMHO_00958 5.5e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPGFCMHO_00959 2.3e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPGFCMHO_00960 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NPGFCMHO_00961 9.9e-58
NPGFCMHO_00962 1.2e-174 degV S DegV family
NPGFCMHO_00963 2.2e-240 cpdA S Calcineurin-like phosphoesterase
NPGFCMHO_00964 9e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NPGFCMHO_00965 2e-71 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPGFCMHO_00966 4.2e-106 ypsA S Belongs to the UPF0398 family
NPGFCMHO_00967 1.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPGFCMHO_00968 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NPGFCMHO_00969 1.2e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPGFCMHO_00970 6.7e-116 dnaD L DnaD domain protein
NPGFCMHO_00971 2.9e-259 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NPGFCMHO_00972 4.8e-90 ypmB S Protein conserved in bacteria
NPGFCMHO_00973 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NPGFCMHO_00974 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NPGFCMHO_00975 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NPGFCMHO_00976 4.4e-169 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
NPGFCMHO_00977 3e-176 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NPGFCMHO_00978 4.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NPGFCMHO_00979 5.2e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPGFCMHO_00980 1.6e-272 V ABC-type multidrug transport system, ATPase and permease components
NPGFCMHO_00981 2.2e-290 V ABC-type multidrug transport system, ATPase and permease components
NPGFCMHO_00982 1.6e-159 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
NPGFCMHO_00983 6.1e-160 rbsU U ribose uptake protein RbsU
NPGFCMHO_00984 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NPGFCMHO_00985 8e-84 6.3.3.2 S ASCH
NPGFCMHO_00986 1.2e-134 2.4.2.3 F Phosphorylase superfamily
NPGFCMHO_00987 1.5e-88 2.3.1.57 K Acetyltransferase (GNAT) family
NPGFCMHO_00988 1.4e-98 rimL J Acetyltransferase (GNAT) domain
NPGFCMHO_00989 2.5e-43
NPGFCMHO_00990 2.7e-51 S endonuclease activity
NPGFCMHO_00991 3.6e-151 S Fic/DOC family
NPGFCMHO_00992 6e-143 3.1.3.48 T Tyrosine phosphatase family
NPGFCMHO_00994 1.4e-135
NPGFCMHO_00995 2.1e-63
NPGFCMHO_00996 1.6e-48 S MazG-like family
NPGFCMHO_00997 1.9e-152 S Protein of unknown function (DUF2785)
NPGFCMHO_00998 1.2e-22 K Acetyltransferase (GNAT) domain
NPGFCMHO_00999 4.5e-36 K Acetyltransferase (GNAT) domain
NPGFCMHO_01000 1.1e-48
NPGFCMHO_01001 5e-282 V ABC transporter transmembrane region
NPGFCMHO_01002 1.7e-84 C nitroreductase
NPGFCMHO_01003 2e-294 V ABC-type multidrug transport system, ATPase and permease components
NPGFCMHO_01004 2e-149 ropB K Helix-turn-helix domain
NPGFCMHO_01005 1.6e-128 qmcA O prohibitin homologues
NPGFCMHO_01006 1.2e-141 S Protein of unknown function (DUF975)
NPGFCMHO_01007 1.3e-54 K sequence-specific DNA binding
NPGFCMHO_01008 1e-09 K sequence-specific DNA binding
NPGFCMHO_01009 2e-105 speG J Acetyltransferase (GNAT) domain
NPGFCMHO_01010 2.2e-139
NPGFCMHO_01011 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPGFCMHO_01012 2e-42 rpiB 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
NPGFCMHO_01013 8.4e-50
NPGFCMHO_01014 2.8e-28
NPGFCMHO_01015 8.4e-119 drgA C nitroreductase
NPGFCMHO_01016 0.0 1.3.5.4 C FMN_bind
NPGFCMHO_01017 1.1e-167 lysR7 K LysR substrate binding domain
NPGFCMHO_01018 3.3e-158 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPGFCMHO_01019 5.3e-231 hom1 1.1.1.3 E homoserine dehydrogenase
NPGFCMHO_01020 3.3e-283 thrC 4.2.3.1 E Threonine synthase
NPGFCMHO_01021 2.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPGFCMHO_01022 4.8e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPGFCMHO_01023 0.0 pepO 3.4.24.71 O Peptidase family M13
NPGFCMHO_01024 0.0 XK27_06780 V ABC transporter permease
NPGFCMHO_01025 2.9e-128 XK27_06785 V ABC transporter, ATP-binding protein
NPGFCMHO_01026 5.7e-126 alkD L DNA alkylation repair enzyme
NPGFCMHO_01027 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NPGFCMHO_01028 4.5e-105 pncA Q Isochorismatase family
NPGFCMHO_01029 3.3e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPGFCMHO_01030 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NPGFCMHO_01031 1.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPGFCMHO_01032 3.1e-242 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPGFCMHO_01033 2.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NPGFCMHO_01034 2.1e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPGFCMHO_01035 6.8e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPGFCMHO_01036 3.8e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPGFCMHO_01037 5.4e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPGFCMHO_01038 2.3e-303 I Protein of unknown function (DUF2974)
NPGFCMHO_01039 5.1e-153 yxeH S hydrolase
NPGFCMHO_01040 1.7e-161 XK27_05540 S DUF218 domain
NPGFCMHO_01041 3.5e-52 ybjQ S Belongs to the UPF0145 family
NPGFCMHO_01042 4.4e-229 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
NPGFCMHO_01043 1.1e-167
NPGFCMHO_01044 4e-133
NPGFCMHO_01045 1e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NPGFCMHO_01046 8.1e-22
NPGFCMHO_01047 2.3e-108
NPGFCMHO_01048 2.1e-138
NPGFCMHO_01049 3.3e-124 skfE V ATPases associated with a variety of cellular activities
NPGFCMHO_01050 9.6e-59 yvoA_1 K Transcriptional regulator, GntR family
NPGFCMHO_01051 5.4e-247 pepT 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPGFCMHO_01052 3.2e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPGFCMHO_01053 2.5e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
NPGFCMHO_01054 2.9e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPGFCMHO_01055 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPGFCMHO_01056 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NPGFCMHO_01057 3.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NPGFCMHO_01058 1.6e-137 recO L Involved in DNA repair and RecF pathway recombination
NPGFCMHO_01059 1.1e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPGFCMHO_01060 1.2e-91 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPGFCMHO_01061 4.7e-174 phoH T phosphate starvation-inducible protein PhoH
NPGFCMHO_01062 4.1e-40 yqeY S YqeY-like protein
NPGFCMHO_01063 1.5e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NPGFCMHO_01064 6.6e-156 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPGFCMHO_01065 1.3e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPGFCMHO_01066 3.8e-107 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPGFCMHO_01067 2.4e-144 E GDSL-like Lipase/Acylhydrolase family
NPGFCMHO_01068 6.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NPGFCMHO_01069 1.4e-223 patA 2.6.1.1 E Aminotransferase
NPGFCMHO_01070 7e-32
NPGFCMHO_01071 7.2e-164 htpX O Peptidase family M48
NPGFCMHO_01073 4.5e-76 S HIRAN
NPGFCMHO_01075 6.3e-190 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NPGFCMHO_01076 8.8e-118 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NPGFCMHO_01077 7.2e-169 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NPGFCMHO_01078 1.3e-209 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NPGFCMHO_01079 5.5e-225 KQ helix_turn_helix, mercury resistance
NPGFCMHO_01080 2.1e-108 V Abi-like protein
NPGFCMHO_01081 1.3e-37 V Abi-like protein
NPGFCMHO_01082 2.4e-25 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPGFCMHO_01083 1.1e-181 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPGFCMHO_01084 6.1e-172 S Acyltransferase family
NPGFCMHO_01085 8.6e-265 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
NPGFCMHO_01086 1.1e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
NPGFCMHO_01087 8.1e-213
NPGFCMHO_01088 6.8e-195 M Glycosyl transferase family 2
NPGFCMHO_01089 4.7e-199 wbbI M transferase activity, transferring glycosyl groups
NPGFCMHO_01090 2.3e-198 cps1B GT2,GT4 M Glycosyl transferases group 1
NPGFCMHO_01091 4.5e-160 GT2 S Glycosyl transferase family 2
NPGFCMHO_01092 2.2e-184 2.4.1.308 GT11 S N-acetyllactosaminide 3-alpha-galactosyltransferase activity
NPGFCMHO_01093 1.5e-124 M Glycosyltransferase sugar-binding region containing DXD motif
NPGFCMHO_01094 2.9e-90 pssE S Glycosyltransferase family 28 C-terminal domain
NPGFCMHO_01095 6.8e-83 cpsF M Oligosaccharide biosynthesis protein Alg14 like
NPGFCMHO_01096 1.7e-122 rfbP M Bacterial sugar transferase
NPGFCMHO_01097 1.7e-145 ywqE 3.1.3.48 GM PHP domain protein
NPGFCMHO_01098 3.3e-125 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NPGFCMHO_01099 1.5e-142 epsB M biosynthesis protein
NPGFCMHO_01100 6.7e-163 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPGFCMHO_01101 1.1e-59 K DNA-templated transcription, initiation
NPGFCMHO_01102 9.3e-166
NPGFCMHO_01103 2.5e-121 frnE Q DSBA-like thioredoxin domain
NPGFCMHO_01104 7.7e-225
NPGFCMHO_01105 1.2e-70 S Domain of unknown function (DUF4767)
NPGFCMHO_01106 1.5e-81
NPGFCMHO_01107 6.7e-89 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPGFCMHO_01108 1.2e-103 engB D Necessary for normal cell division and for the maintenance of normal septation
NPGFCMHO_01109 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPGFCMHO_01110 9.5e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPGFCMHO_01111 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPGFCMHO_01112 7.7e-160
NPGFCMHO_01113 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPGFCMHO_01114 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPGFCMHO_01115 7.5e-34 rpsT J Binds directly to 16S ribosomal RNA
NPGFCMHO_01116 1.2e-177 holA 2.7.7.7 L DNA polymerase III delta subunit
NPGFCMHO_01117 0.0 comEC S Competence protein ComEC
NPGFCMHO_01118 2.4e-79 comEA L Competence protein ComEA
NPGFCMHO_01119 2.5e-186 ylbL T Belongs to the peptidase S16 family
NPGFCMHO_01120 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPGFCMHO_01121 7.2e-95 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NPGFCMHO_01122 6.1e-52 ylbG S UPF0298 protein
NPGFCMHO_01123 5.9e-211 ftsW D Belongs to the SEDS family
NPGFCMHO_01124 0.0 typA T GTP-binding protein TypA
NPGFCMHO_01125 5.2e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPGFCMHO_01126 3e-34 ykzG S Belongs to the UPF0356 family
NPGFCMHO_01127 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPGFCMHO_01128 9.9e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NPGFCMHO_01129 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPGFCMHO_01130 5.1e-116 S Repeat protein
NPGFCMHO_01131 2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NPGFCMHO_01132 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPGFCMHO_01133 1.6e-57 XK27_04120 S Putative amino acid metabolism
NPGFCMHO_01134 3.9e-215 iscS 2.8.1.7 E Aminotransferase class V
NPGFCMHO_01135 1.6e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPGFCMHO_01137 9.7e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NPGFCMHO_01138 2e-32 cspA K 'Cold-shock' DNA-binding domain
NPGFCMHO_01139 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPGFCMHO_01140 2.1e-119 gpsB D DivIVA domain protein
NPGFCMHO_01141 4.8e-148 ylmH S S4 domain protein
NPGFCMHO_01142 2e-27 yggT S YGGT family
NPGFCMHO_01143 3.6e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPGFCMHO_01144 8.9e-235 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPGFCMHO_01145 4.1e-240 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPGFCMHO_01146 4.8e-154 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPGFCMHO_01147 1.2e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPGFCMHO_01148 2.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPGFCMHO_01149 1.6e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPGFCMHO_01150 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NPGFCMHO_01151 6.3e-55 ftsL D Cell division protein FtsL
NPGFCMHO_01152 1.3e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPGFCMHO_01153 4.1e-77 mraZ K Belongs to the MraZ family
NPGFCMHO_01154 6.1e-52 S Protein of unknown function (DUF3397)
NPGFCMHO_01155 3.6e-13 S Protein of unknown function (DUF4044)
NPGFCMHO_01156 5.4e-95 mreD
NPGFCMHO_01157 1e-143 mreC M Involved in formation and maintenance of cell shape
NPGFCMHO_01158 6.4e-166 mreB D cell shape determining protein MreB
NPGFCMHO_01159 9.5e-112 radC L DNA repair protein
NPGFCMHO_01160 9.2e-124 S Haloacid dehalogenase-like hydrolase
NPGFCMHO_01161 2.8e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPGFCMHO_01162 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPGFCMHO_01163 0.0 3.6.3.8 P P-type ATPase
NPGFCMHO_01164 4.2e-211 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NPGFCMHO_01165 7.8e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPGFCMHO_01166 5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPGFCMHO_01167 2.1e-216 iscS2 2.8.1.7 E Aminotransferase class V
NPGFCMHO_01168 6.5e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPGFCMHO_01170 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPGFCMHO_01171 2.7e-82 yueI S Protein of unknown function (DUF1694)
NPGFCMHO_01172 3e-240 rarA L recombination factor protein RarA
NPGFCMHO_01174 5.2e-81 usp6 T universal stress protein
NPGFCMHO_01175 7.3e-225 rodA D Belongs to the SEDS family
NPGFCMHO_01176 1.3e-34 S Protein of unknown function (DUF2969)
NPGFCMHO_01177 2e-51 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NPGFCMHO_01178 2.5e-15 S DNA-directed RNA polymerase subunit beta
NPGFCMHO_01179 2.2e-179 mbl D Cell shape determining protein MreB Mrl
NPGFCMHO_01180 2e-30 ywzB S Protein of unknown function (DUF1146)
NPGFCMHO_01181 1.1e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NPGFCMHO_01182 3.3e-248 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPGFCMHO_01183 1.4e-170 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPGFCMHO_01184 5.1e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPGFCMHO_01185 5.7e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPGFCMHO_01186 5.9e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPGFCMHO_01187 1.2e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPGFCMHO_01188 1.6e-126 atpB C it plays a direct role in the translocation of protons across the membrane
NPGFCMHO_01189 1.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPGFCMHO_01190 1.2e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPGFCMHO_01191 5.4e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPGFCMHO_01192 1e-196 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPGFCMHO_01193 5.5e-112 tdk 2.7.1.21 F thymidine kinase
NPGFCMHO_01194 4.9e-262 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
NPGFCMHO_01195 7.2e-197 ampC V Beta-lactamase
NPGFCMHO_01198 1.4e-72
NPGFCMHO_01199 3.2e-104 EGP Major facilitator Superfamily
NPGFCMHO_01200 5.6e-88 EGP Major facilitator Superfamily
NPGFCMHO_01201 5.4e-261 pgi 5.3.1.9 G Belongs to the GPI family
NPGFCMHO_01202 1.4e-107 vanZ V VanZ like family
NPGFCMHO_01203 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPGFCMHO_01204 2.8e-271 T PhoQ Sensor
NPGFCMHO_01205 9e-130 K Transcriptional regulatory protein, C terminal
NPGFCMHO_01206 9.2e-68 S SdpI/YhfL protein family
NPGFCMHO_01207 2.9e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPGFCMHO_01208 1.8e-80 patB 4.4.1.8 E Aminotransferase, class I
NPGFCMHO_01209 1e-76 M Protein of unknown function (DUF3737)
NPGFCMHO_01210 2.7e-24 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NPGFCMHO_01211 3.2e-270 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
NPGFCMHO_01213 7.3e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPGFCMHO_01214 1.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
NPGFCMHO_01215 4.7e-88 comGF U Putative Competence protein ComGF
NPGFCMHO_01217 3.7e-67
NPGFCMHO_01218 1.1e-36 comGC U Required for transformation and DNA binding
NPGFCMHO_01219 4.7e-177 comGB NU type II secretion system
NPGFCMHO_01220 5.8e-180 comGA NU Type II IV secretion system protein
NPGFCMHO_01221 1.5e-132 yebC K Transcriptional regulatory protein
NPGFCMHO_01222 7.3e-97 S VanZ like family
NPGFCMHO_01223 5.1e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPGFCMHO_01224 4.5e-163 znuA P Belongs to the bacterial solute-binding protein 9 family
NPGFCMHO_01225 8.5e-150 yisY 1.11.1.10 S Alpha/beta hydrolase family
NPGFCMHO_01226 4.8e-115
NPGFCMHO_01227 8e-179 S Putative adhesin
NPGFCMHO_01228 5.3e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPGFCMHO_01229 2.3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPGFCMHO_01230 4.4e-149 S Sucrose-6F-phosphate phosphohydrolase
NPGFCMHO_01231 5.9e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPGFCMHO_01232 8.1e-174 ybbR S YbbR-like protein
NPGFCMHO_01233 3.4e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPGFCMHO_01234 1.3e-209 potD P ABC transporter
NPGFCMHO_01235 2.2e-137 potC P ABC transporter permease
NPGFCMHO_01236 7.1e-131 potB P ABC transporter permease
NPGFCMHO_01237 1.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPGFCMHO_01238 5.2e-167 murB 1.3.1.98 M Cell wall formation
NPGFCMHO_01239 9.5e-100 dnaQ 2.7.7.7 L DNA polymerase III
NPGFCMHO_01240 1.3e-84 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NPGFCMHO_01241 2.5e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NPGFCMHO_01242 3.1e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPGFCMHO_01243 8e-157 ycsE S Sucrose-6F-phosphate phosphohydrolase
NPGFCMHO_01244 2.9e-93
NPGFCMHO_01245 2.3e-91
NPGFCMHO_01247 1e-107 3.2.2.20 K acetyltransferase
NPGFCMHO_01248 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NPGFCMHO_01249 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPGFCMHO_01250 2.5e-28 secG U Preprotein translocase
NPGFCMHO_01251 3.1e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPGFCMHO_01252 1.9e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPGFCMHO_01253 6e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NPGFCMHO_01254 3.2e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPGFCMHO_01255 2.3e-187 cggR K Putative sugar-binding domain
NPGFCMHO_01257 1.2e-277 ycaM E amino acid
NPGFCMHO_01258 2.1e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPGFCMHO_01259 6.2e-171 whiA K May be required for sporulation
NPGFCMHO_01260 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NPGFCMHO_01261 6e-160 rapZ S Displays ATPase and GTPase activities
NPGFCMHO_01262 1.1e-90 S Short repeat of unknown function (DUF308)
NPGFCMHO_01263 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPGFCMHO_01264 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPGFCMHO_01265 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NPGFCMHO_01266 1.6e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NPGFCMHO_01267 5.2e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NPGFCMHO_01268 1.4e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPGFCMHO_01269 3.5e-180 lacR K Transcriptional regulator
NPGFCMHO_01270 7.5e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NPGFCMHO_01271 6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPGFCMHO_01272 8.8e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NPGFCMHO_01273 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPGFCMHO_01274 3.8e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPGFCMHO_01275 3.3e-35
NPGFCMHO_01276 6.2e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPGFCMHO_01277 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPGFCMHO_01278 4.5e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPGFCMHO_01279 5.7e-126 comFC S Competence protein
NPGFCMHO_01280 1.1e-242 comFA L Helicase C-terminal domain protein
NPGFCMHO_01281 2.5e-118 yvyE 3.4.13.9 S YigZ family
NPGFCMHO_01282 2.7e-192 tagO 2.7.8.33, 2.7.8.35 M transferase
NPGFCMHO_01283 1.2e-209 rny S Endoribonuclease that initiates mRNA decay
NPGFCMHO_01284 1.9e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPGFCMHO_01285 1.4e-96 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPGFCMHO_01286 4.3e-125 ymfM S Helix-turn-helix domain
NPGFCMHO_01287 4.1e-130 IQ Enoyl-(Acyl carrier protein) reductase
NPGFCMHO_01288 2.9e-232 S Peptidase M16
NPGFCMHO_01289 2.2e-229 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
NPGFCMHO_01290 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NPGFCMHO_01291 4.6e-76 WQ51_03320 S Protein of unknown function (DUF1149)
NPGFCMHO_01292 2.7e-105 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPGFCMHO_01293 5.4e-212 yubA S AI-2E family transporter
NPGFCMHO_01294 9.9e-67 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NPGFCMHO_01295 4.8e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NPGFCMHO_01296 3.9e-234 N Uncharacterized conserved protein (DUF2075)
NPGFCMHO_01297 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NPGFCMHO_01298 1.4e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPGFCMHO_01299 4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPGFCMHO_01300 6.7e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
NPGFCMHO_01301 3.3e-112 yjbK S CYTH
NPGFCMHO_01302 7e-107 yjbH Q Thioredoxin
NPGFCMHO_01303 1.7e-162 coiA 3.6.4.12 S Competence protein
NPGFCMHO_01304 5.5e-118 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NPGFCMHO_01305 4.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPGFCMHO_01306 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPGFCMHO_01307 4.2e-40 ptsH G phosphocarrier protein HPR
NPGFCMHO_01308 6.9e-26
NPGFCMHO_01309 0.0 clpE O Belongs to the ClpA ClpB family
NPGFCMHO_01310 1.1e-43 XK27_09445 S Domain of unknown function (DUF1827)
NPGFCMHO_01311 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NPGFCMHO_01312 1e-156 hlyX S Transporter associated domain
NPGFCMHO_01313 3e-78
NPGFCMHO_01314 4.9e-90
NPGFCMHO_01315 2.4e-112 ygaC J Belongs to the UPF0374 family
NPGFCMHO_01316 2.1e-143 recX 2.4.1.337 GT4 S Regulatory protein RecX
NPGFCMHO_01317 9.2e-264 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPGFCMHO_01318 2.9e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NPGFCMHO_01319 3.5e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NPGFCMHO_01320 9.3e-217 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
NPGFCMHO_01321 1.3e-179 D Alpha beta
NPGFCMHO_01322 2.4e-07
NPGFCMHO_01323 4.3e-152 S haloacid dehalogenase-like hydrolase
NPGFCMHO_01324 2.8e-205 EGP Major facilitator Superfamily
NPGFCMHO_01325 1.1e-261 glnA 6.3.1.2 E glutamine synthetase
NPGFCMHO_01326 9.7e-169 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPGFCMHO_01327 1.1e-18 S Protein of unknown function (DUF3042)
NPGFCMHO_01328 1.5e-57 yqhL P Rhodanese-like protein
NPGFCMHO_01329 6e-35 yqgQ S Bacterial protein of unknown function (DUF910)
NPGFCMHO_01330 2.4e-119 gluP 3.4.21.105 S Rhomboid family
NPGFCMHO_01331 5.6e-87 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPGFCMHO_01332 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPGFCMHO_01333 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NPGFCMHO_01334 0.0 S membrane
NPGFCMHO_01335 4e-65 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPGFCMHO_01336 1.3e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NPGFCMHO_01337 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPGFCMHO_01338 8.1e-204 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPGFCMHO_01339 2.8e-63 yodB K Transcriptional regulator, HxlR family
NPGFCMHO_01340 9.6e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPGFCMHO_01341 3.8e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NPGFCMHO_01342 1.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPGFCMHO_01343 1.9e-281 arlS 2.7.13.3 T Histidine kinase
NPGFCMHO_01344 1.1e-130 K response regulator
NPGFCMHO_01345 2.9e-96 yceD S Uncharacterized ACR, COG1399
NPGFCMHO_01346 5.8e-219 ylbM S Belongs to the UPF0348 family
NPGFCMHO_01347 8.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPGFCMHO_01348 1.7e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NPGFCMHO_01349 4.4e-120 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPGFCMHO_01350 7.3e-211 yqeH S Ribosome biogenesis GTPase YqeH
NPGFCMHO_01351 3.5e-91 yqeG S HAD phosphatase, family IIIA
NPGFCMHO_01352 9.8e-191 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NPGFCMHO_01353 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPGFCMHO_01354 2.4e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NPGFCMHO_01355 4e-87 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPGFCMHO_01356 1.3e-131 S domain protein
NPGFCMHO_01357 4.8e-171 V ABC transporter
NPGFCMHO_01358 1.9e-74 S Protein of unknown function (DUF3021)
NPGFCMHO_01359 4.7e-73 K LytTr DNA-binding domain
NPGFCMHO_01360 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPGFCMHO_01361 2.7e-163 dnaI L Primosomal protein DnaI
NPGFCMHO_01362 2.3e-251 dnaB L Replication initiation and membrane attachment
NPGFCMHO_01363 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPGFCMHO_01364 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPGFCMHO_01365 1.1e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPGFCMHO_01366 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPGFCMHO_01367 5.7e-230 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
NPGFCMHO_01368 1.4e-211 EGP Major facilitator Superfamily
NPGFCMHO_01369 4e-69 rmaI K Transcriptional regulator
NPGFCMHO_01370 5.9e-12
NPGFCMHO_01371 1.2e-76 K UTRA
NPGFCMHO_01372 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NPGFCMHO_01373 1.2e-117 cutC P Participates in the control of copper homeostasis
NPGFCMHO_01374 2.4e-197 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPGFCMHO_01375 5.9e-94 S Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
NPGFCMHO_01376 3.9e-181 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
NPGFCMHO_01377 6.1e-257 3.5.1.18 E Peptidase family M20/M25/M40
NPGFCMHO_01378 3.2e-130 ymfC K UTRA
NPGFCMHO_01379 7.4e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPGFCMHO_01380 1.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NPGFCMHO_01381 3.3e-15 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPGFCMHO_01382 4.4e-42 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPGFCMHO_01383 3e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPGFCMHO_01384 2.1e-227 ecsB U ABC transporter
NPGFCMHO_01385 2.4e-133 ecsA V ABC transporter, ATP-binding protein
NPGFCMHO_01386 2.4e-77 hit FG Scavenger mRNA decapping enzyme C-term binding
NPGFCMHO_01387 2e-64
NPGFCMHO_01388 4.4e-37 S YtxH-like protein
NPGFCMHO_01389 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPGFCMHO_01390 1.6e-185 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPGFCMHO_01391 0.0 L AAA domain
NPGFCMHO_01392 1.1e-231 yhaO L Ser Thr phosphatase family protein
NPGFCMHO_01393 3.3e-56 yheA S Belongs to the UPF0342 family
NPGFCMHO_01394 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPGFCMHO_01395 3.6e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPGFCMHO_01397 1.3e-259 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
NPGFCMHO_01398 1.3e-66
NPGFCMHO_01399 2e-94 3.6.1.55 L NUDIX domain
NPGFCMHO_01400 2.2e-153 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
NPGFCMHO_01401 3.9e-198 V Beta-lactamase
NPGFCMHO_01402 8.4e-63
NPGFCMHO_01403 0.0 L helicase activity
NPGFCMHO_01404 6.4e-227 K DNA binding
NPGFCMHO_01405 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
NPGFCMHO_01406 8.6e-252 mod 2.1.1.72, 3.1.21.5 L DNA methylase
NPGFCMHO_01407 7.4e-39 K Cro/C1-type HTH DNA-binding domain
NPGFCMHO_01408 3.5e-302
NPGFCMHO_01409 3.2e-36
NPGFCMHO_01410 1.3e-145
NPGFCMHO_01411 2.3e-72
NPGFCMHO_01413 2.7e-23
NPGFCMHO_01414 4.9e-51
NPGFCMHO_01415 1.6e-221 L Protein of unknown function (DUF2800)
NPGFCMHO_01416 1.7e-99 S Protein of unknown function (DUF2815)
NPGFCMHO_01417 0.0 polA_2 2.7.7.7 L DNA polymerase
NPGFCMHO_01418 3.3e-70 S Psort location Cytoplasmic, score
NPGFCMHO_01419 0.0 S Phage plasmid primase, P4
NPGFCMHO_01420 2.4e-46 S VRR_NUC
NPGFCMHO_01421 2.5e-258 L SNF2 family N-terminal domain
NPGFCMHO_01422 2.8e-87
NPGFCMHO_01423 3.3e-100
NPGFCMHO_01424 2.2e-245 2.1.1.72 KL DNA methylase
NPGFCMHO_01425 2.3e-113 S Psort location Cytoplasmic, score
NPGFCMHO_01426 6.2e-31 S Domain of unknown function (DUF5049)
NPGFCMHO_01427 2.6e-302 S overlaps another CDS with the same product name
NPGFCMHO_01428 2.5e-247 S Phage portal protein
NPGFCMHO_01429 2.9e-122 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NPGFCMHO_01430 8.2e-221 S Phage capsid family
NPGFCMHO_01431 4.3e-43 S Phage gp6-like head-tail connector protein
NPGFCMHO_01432 6.9e-68 S Phage head-tail joining protein
NPGFCMHO_01433 3.6e-70 S Bacteriophage holin family
NPGFCMHO_01434 2.3e-142 M Glycosyl hydrolases family 25
NPGFCMHO_01435 8e-35
NPGFCMHO_01436 0.0 L Recombinase zinc beta ribbon domain
NPGFCMHO_01437 9.1e-300 L Recombinase
NPGFCMHO_01438 6.3e-16 2.1.1.303 K DNA-binding transcription factor activity
NPGFCMHO_01439 9.2e-198 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NPGFCMHO_01440 3.1e-183 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NPGFCMHO_01441 2.1e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPGFCMHO_01442 9.6e-121 spaE S ABC-2 family transporter protein
NPGFCMHO_01443 1.8e-130 mutF V ABC transporter, ATP-binding protein
NPGFCMHO_01444 4.4e-242 nhaC C Na H antiporter NhaC
NPGFCMHO_01445 9.6e-163 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
NPGFCMHO_01446 3.3e-95 S UPF0397 protein
NPGFCMHO_01447 0.0 ykoD P ABC transporter, ATP-binding protein
NPGFCMHO_01448 3.1e-142 cbiQ P cobalt transport
NPGFCMHO_01449 3.2e-119 ybhL S Belongs to the BI1 family
NPGFCMHO_01450 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
NPGFCMHO_01451 4.2e-65 S Domain of unknown function (DUF4430)
NPGFCMHO_01452 8.1e-88 S ECF transporter, substrate-specific component
NPGFCMHO_01453 2.1e-94 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
NPGFCMHO_01454 4.4e-129 L Helix-turn-helix domain
NPGFCMHO_01455 2.3e-23 L hmm pf00665
NPGFCMHO_01456 1.2e-39 L hmm pf00665
NPGFCMHO_01457 9.6e-152 S hydrolase
NPGFCMHO_01459 7.3e-169 yegS 2.7.1.107 G Lipid kinase
NPGFCMHO_01460 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPGFCMHO_01461 8.1e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPGFCMHO_01462 4.3e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPGFCMHO_01463 1.7e-207 camS S sex pheromone
NPGFCMHO_01464 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPGFCMHO_01465 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NPGFCMHO_01466 9.4e-115 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
NPGFCMHO_01467 5.3e-102 S ECF transporter, substrate-specific component
NPGFCMHO_01469 6.7e-86 ydcK S Belongs to the SprT family
NPGFCMHO_01470 7e-135 M Glycosyltransferase sugar-binding region containing DXD motif
NPGFCMHO_01471 2.1e-258 epsU S Polysaccharide biosynthesis protein
NPGFCMHO_01472 4.7e-229 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPGFCMHO_01473 7e-147
NPGFCMHO_01474 7.9e-288 V ABC transporter transmembrane region
NPGFCMHO_01475 0.0 pacL 3.6.3.8 P P-type ATPase
NPGFCMHO_01476 3.6e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPGFCMHO_01477 2e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPGFCMHO_01478 4.5e-288 tuaG GT2 M Glycosyltransferase like family 2
NPGFCMHO_01479 2.1e-58 tuaG GT2 M Glycosyltransferase like family 2
NPGFCMHO_01480 2.9e-204 csaB M Glycosyl transferases group 1
NPGFCMHO_01481 4.2e-141 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPGFCMHO_01482 1.5e-67 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NPGFCMHO_01483 9.5e-124 gntR1 K UTRA
NPGFCMHO_01484 9.3e-190
NPGFCMHO_01485 1.4e-52 P Rhodanese Homology Domain
NPGFCMHO_01488 1.2e-166 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
NPGFCMHO_01489 1.8e-145 K SIS domain
NPGFCMHO_01491 1.4e-189 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
NPGFCMHO_01492 1.7e-59 yjgN S Bacterial protein of unknown function (DUF898)
NPGFCMHO_01494 4.8e-99 M LysM domain protein
NPGFCMHO_01495 1.3e-110 M LysM domain protein
NPGFCMHO_01496 5.5e-135 S Putative ABC-transporter type IV
NPGFCMHO_01497 2.3e-61 psiE S Phosphate-starvation-inducible E
NPGFCMHO_01498 3.4e-94 K acetyltransferase
NPGFCMHO_01499 1e-149 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPGFCMHO_01501 5.1e-164 yvgN C Aldo keto reductase
NPGFCMHO_01502 6.8e-248 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NPGFCMHO_01503 7.5e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NPGFCMHO_01504 0.0 lhr L DEAD DEAH box helicase
NPGFCMHO_01505 1.6e-252 P P-loop Domain of unknown function (DUF2791)
NPGFCMHO_01506 0.0 S TerB-C domain
NPGFCMHO_01507 1.3e-99 4.1.1.44 S decarboxylase
NPGFCMHO_01508 5.1e-72
NPGFCMHO_01509 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NPGFCMHO_01510 1.9e-232 cycA E Amino acid permease
NPGFCMHO_01528 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPGFCMHO_01529 4.5e-183 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPGFCMHO_01530 4.2e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
NPGFCMHO_01531 2.6e-219 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
NPGFCMHO_01543 3.8e-60
NPGFCMHO_01560 1.4e-216 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPGFCMHO_01561 2.1e-102 J Acetyltransferase (GNAT) domain
NPGFCMHO_01562 1.5e-106 yjbF S SNARE associated Golgi protein
NPGFCMHO_01563 7.1e-152 I alpha/beta hydrolase fold
NPGFCMHO_01564 4.4e-144 hipB K Helix-turn-helix
NPGFCMHO_01565 7.2e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NPGFCMHO_01566 6e-180
NPGFCMHO_01567 2.1e-123 S SNARE associated Golgi protein
NPGFCMHO_01568 6.1e-137 cof S haloacid dehalogenase-like hydrolase
NPGFCMHO_01569 0.0 ydgH S MMPL family
NPGFCMHO_01570 3.2e-98 yobS K Bacterial regulatory proteins, tetR family
NPGFCMHO_01571 1.4e-167 3.5.2.6 V Beta-lactamase enzyme family
NPGFCMHO_01572 5.4e-167 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
NPGFCMHO_01573 1.4e-80 yjcF S Acetyltransferase (GNAT) domain
NPGFCMHO_01574 6e-97 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NPGFCMHO_01575 1.1e-77 yybA 2.3.1.57 K Transcriptional regulator
NPGFCMHO_01576 8.7e-52 ypaA S Protein of unknown function (DUF1304)
NPGFCMHO_01577 3e-240 G Bacterial extracellular solute-binding protein
NPGFCMHO_01578 7.9e-257 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
NPGFCMHO_01579 5e-148 gtsC P Binding-protein-dependent transport system inner membrane component
NPGFCMHO_01580 9.5e-158 gtsB P ABC-type sugar transport systems, permease components
NPGFCMHO_01581 7.1e-203 malK P ATPases associated with a variety of cellular activities
NPGFCMHO_01582 4.9e-284 pipD E Dipeptidase
NPGFCMHO_01583 6.7e-132 endA F DNA RNA non-specific endonuclease
NPGFCMHO_01584 1e-12 dkg S reductase
NPGFCMHO_01585 9.8e-77 dkg S reductase
NPGFCMHO_01586 1.1e-201 ltrA S Bacterial low temperature requirement A protein (LtrA)
NPGFCMHO_01587 4.5e-185 dnaQ 2.7.7.7 L EXOIII
NPGFCMHO_01588 1.3e-140 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NPGFCMHO_01589 3.1e-113 yviA S Protein of unknown function (DUF421)
NPGFCMHO_01590 4e-75 S Protein of unknown function (DUF3290)
NPGFCMHO_01591 1.5e-247 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPGFCMHO_01592 1.9e-95 S PAS domain
NPGFCMHO_01593 6.3e-145 pnuC H nicotinamide mononucleotide transporter
NPGFCMHO_01594 0.0 M domain protein
NPGFCMHO_01595 4.6e-07 GM domain, Protein
NPGFCMHO_01596 2e-43 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPGFCMHO_01597 8.1e-162 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPGFCMHO_01598 2.3e-128 S PAS domain
NPGFCMHO_01599 2.7e-239 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPGFCMHO_01600 3.9e-217 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
NPGFCMHO_01601 8e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPGFCMHO_01602 0.0 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
NPGFCMHO_01603 5e-69
NPGFCMHO_01604 0.0 uvrA3 L excinuclease ABC, A subunit
NPGFCMHO_01605 0.0 oppA E ABC transporter substrate-binding protein
NPGFCMHO_01606 7.6e-159 EG EamA-like transporter family
NPGFCMHO_01607 1.6e-285 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPGFCMHO_01608 0.0 bglP 2.7.1.211 G phosphotransferase system
NPGFCMHO_01609 7.1e-150 licT K CAT RNA binding domain
NPGFCMHO_01610 0.0 fhaB M Rib/alpha-like repeat
NPGFCMHO_01611 9.8e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPGFCMHO_01612 6.7e-164 coaA 2.7.1.33 F Pantothenic acid kinase
NPGFCMHO_01613 6.2e-105 E GDSL-like Lipase/Acylhydrolase
NPGFCMHO_01614 4.1e-245 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPGFCMHO_01615 4.9e-82 rarA L MgsA AAA+ ATPase C terminal
NPGFCMHO_01616 2.3e-122 K Helix-turn-helix domain, rpiR family
NPGFCMHO_01617 1.1e-135 yvpB S Peptidase_C39 like family
NPGFCMHO_01618 0.0 helD 3.6.4.12 L DNA helicase
NPGFCMHO_01619 1.2e-117 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NPGFCMHO_01621 2.9e-151 3.6.3.8 P P-type ATPase
NPGFCMHO_01622 2.3e-250 3.6.3.8 P P-type ATPase
NPGFCMHO_01623 5.6e-258 3.4.16.4 M ErfK YbiS YcfS YnhG
NPGFCMHO_01624 2.3e-48 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPGFCMHO_01625 6.7e-145 rpiR1 K Helix-turn-helix domain, rpiR family
NPGFCMHO_01626 8.2e-128 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NPGFCMHO_01627 0.0 ptsG 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
NPGFCMHO_01628 3.2e-149 xth 3.1.11.2 L exodeoxyribonuclease III
NPGFCMHO_01629 1.3e-52
NPGFCMHO_01630 1.8e-25
NPGFCMHO_01631 8e-125 pgm3 G Phosphoglycerate mutase family
NPGFCMHO_01632 0.0 V FtsX-like permease family
NPGFCMHO_01633 2.2e-134 cysA V ABC transporter, ATP-binding protein
NPGFCMHO_01634 7.3e-280 E amino acid
NPGFCMHO_01635 2.4e-234 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPGFCMHO_01636 5.1e-234 S Putative peptidoglycan binding domain
NPGFCMHO_01637 6.8e-95 M NlpC P60 family protein
NPGFCMHO_01639 1.3e-99 gmk2 2.7.4.8 F Guanylate kinase
NPGFCMHO_01640 9e-44
NPGFCMHO_01641 3.9e-279 S O-antigen ligase like membrane protein
NPGFCMHO_01642 1.8e-110
NPGFCMHO_01643 2.9e-81 nrdI F NrdI Flavodoxin like
NPGFCMHO_01644 3.3e-180 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPGFCMHO_01645 4.1e-81
NPGFCMHO_01646 4.7e-60 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPGFCMHO_01647 1.8e-40
NPGFCMHO_01648 9.6e-80 S Threonine/Serine exporter, ThrE
NPGFCMHO_01649 1.5e-138 thrE S Putative threonine/serine exporter
NPGFCMHO_01650 2.8e-285 S ABC transporter, ATP-binding protein
NPGFCMHO_01651 8.5e-63
NPGFCMHO_01652 3.6e-39
NPGFCMHO_01653 3e-212 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPGFCMHO_01654 0.0 pepF E oligoendopeptidase F
NPGFCMHO_01656 4.1e-257 lctP C L-lactate permease
NPGFCMHO_01657 5.1e-134 znuB U ABC 3 transport family
NPGFCMHO_01658 2.8e-117 fhuC P ABC transporter
NPGFCMHO_01659 8.9e-159 psaA P Belongs to the bacterial solute-binding protein 9 family
NPGFCMHO_01660 1.6e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
NPGFCMHO_01661 6.9e-139 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
NPGFCMHO_01662 0.0 M domain protein
NPGFCMHO_01663 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
NPGFCMHO_01664 6.9e-167 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NPGFCMHO_01665 1.5e-135 fruR K DeoR C terminal sensor domain
NPGFCMHO_01666 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NPGFCMHO_01667 1.6e-222 natB CP ABC-2 family transporter protein
NPGFCMHO_01668 1.2e-166 natA S ABC transporter, ATP-binding protein
NPGFCMHO_01669 2.6e-143 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NPGFCMHO_01670 2.2e-306 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPGFCMHO_01671 2.9e-202 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
NPGFCMHO_01672 7.4e-121 K response regulator
NPGFCMHO_01673 0.0 V ABC transporter
NPGFCMHO_01674 1e-296 V ABC transporter, ATP-binding protein
NPGFCMHO_01675 3.4e-144 XK27_01040 S Protein of unknown function (DUF1129)
NPGFCMHO_01676 3.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPGFCMHO_01677 1.3e-43 yyzM S Bacterial protein of unknown function (DUF951)
NPGFCMHO_01678 2.2e-154 spo0J K Belongs to the ParB family
NPGFCMHO_01679 4.4e-138 soj D Sporulation initiation inhibitor
NPGFCMHO_01680 2.1e-144 noc K Belongs to the ParB family
NPGFCMHO_01681 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NPGFCMHO_01682 1.6e-94 cvpA S Colicin V production protein
NPGFCMHO_01683 1.2e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPGFCMHO_01684 4.4e-149 3.1.3.48 T Tyrosine phosphatase family
NPGFCMHO_01685 6e-199 4.2.1.126 S Bacterial protein of unknown function (DUF871)
NPGFCMHO_01686 3.7e-99 azr 1.5.1.36 S NADPH-dependent FMN reductase
NPGFCMHO_01687 5.3e-98 nqr 1.5.1.36 S NADPH-dependent FMN reductase
NPGFCMHO_01688 1e-108 K WHG domain
NPGFCMHO_01689 8e-38
NPGFCMHO_01690 2.6e-274 pipD E Dipeptidase
NPGFCMHO_01691 4.4e-296 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPGFCMHO_01692 3.8e-297 2.7.1.211 G phosphotransferase system
NPGFCMHO_01693 4.2e-158 K CAT RNA binding domain
NPGFCMHO_01694 6.8e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NPGFCMHO_01695 8.8e-174 hrtB V ABC transporter permease
NPGFCMHO_01696 1.9e-92 ygfC K Bacterial regulatory proteins, tetR family
NPGFCMHO_01697 3.5e-111 G phosphoglycerate mutase
NPGFCMHO_01698 5.5e-115 G Phosphoglycerate mutase family
NPGFCMHO_01699 1.8e-141 aroD S Alpha/beta hydrolase family
NPGFCMHO_01700 2e-106 S Protein of unknown function (DUF975)
NPGFCMHO_01701 2.1e-140 S Belongs to the UPF0246 family
NPGFCMHO_01702 2.2e-52
NPGFCMHO_01703 6.7e-130
NPGFCMHO_01704 1.1e-50 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NPGFCMHO_01705 6.3e-88 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
NPGFCMHO_01706 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NPGFCMHO_01707 3.4e-143 3.4.16.4, 3.5.2.6 V Beta-lactamase enzyme family
NPGFCMHO_01708 8.2e-154 ybbH_2 K Helix-turn-helix domain, rpiR family
NPGFCMHO_01709 2.1e-173 2.7.7.12 C Domain of unknown function (DUF4931)
NPGFCMHO_01710 1.4e-53 aroD 1.1.1.25, 4.2.1.10 E 3-dehydroquinate dehydratase activity
NPGFCMHO_01711 1.1e-156
NPGFCMHO_01712 3e-226 mdtG EGP Major facilitator Superfamily
NPGFCMHO_01713 2.9e-125 puuD S peptidase C26
NPGFCMHO_01714 3.6e-296 V ABC transporter transmembrane region
NPGFCMHO_01715 2.4e-92 ymdB S Macro domain protein
NPGFCMHO_01716 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
NPGFCMHO_01717 1e-300 scrB 3.2.1.26 GH32 G invertase
NPGFCMHO_01718 1.2e-185 scrR K Transcriptional regulator, LacI family
NPGFCMHO_01719 3e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
NPGFCMHO_01720 6.9e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NPGFCMHO_01721 7.1e-132 cobQ S glutamine amidotransferase
NPGFCMHO_01722 1.7e-257 yfnA E Amino Acid
NPGFCMHO_01723 1.6e-163 EG EamA-like transporter family
NPGFCMHO_01724 2.8e-193 asnA 6.3.1.1 F aspartate--ammonia ligase
NPGFCMHO_01725 3.9e-234 S CAAX protease self-immunity
NPGFCMHO_01726 5e-241 steT_1 E amino acid
NPGFCMHO_01727 9.1e-138 puuD S peptidase C26
NPGFCMHO_01728 4.2e-224 yifK E Amino acid permease
NPGFCMHO_01729 3.7e-252 yifK E Amino acid permease
NPGFCMHO_01730 1.8e-65 manO S Domain of unknown function (DUF956)
NPGFCMHO_01731 5.6e-172 manN G system, mannose fructose sorbose family IID component
NPGFCMHO_01732 1.3e-124 manY G PTS system
NPGFCMHO_01733 9.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NPGFCMHO_01743 6.9e-251 yfnA E Amino Acid
NPGFCMHO_01744 0.0 clpE2 O AAA domain (Cdc48 subfamily)
NPGFCMHO_01745 6.5e-157 S Alpha/beta hydrolase of unknown function (DUF915)
NPGFCMHO_01746 2.2e-243 pts13C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPGFCMHO_01747 1.1e-39
NPGFCMHO_01748 6.2e-216 lmrP E Major Facilitator Superfamily
NPGFCMHO_01749 1.2e-174 pbpX2 V Beta-lactamase
NPGFCMHO_01750 4.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPGFCMHO_01751 3.9e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPGFCMHO_01752 2.1e-235 dltB M MBOAT, membrane-bound O-acyltransferase family
NPGFCMHO_01753 2.1e-290 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPGFCMHO_01755 2.8e-45
NPGFCMHO_01756 1.7e-199 ywhK S Membrane
NPGFCMHO_01757 1.2e-58
NPGFCMHO_01758 2.4e-49
NPGFCMHO_01759 3.6e-45
NPGFCMHO_01760 8.3e-18
NPGFCMHO_01761 2.7e-85 ykuL S (CBS) domain
NPGFCMHO_01762 0.0 cadA P P-type ATPase
NPGFCMHO_01763 9.3e-201 napA P Sodium/hydrogen exchanger family
NPGFCMHO_01765 7.7e-283 V ABC transporter transmembrane region
NPGFCMHO_01766 5.9e-160 mutR K Helix-turn-helix XRE-family like proteins
NPGFCMHO_01767 8.9e-27
NPGFCMHO_01768 4.1e-34
NPGFCMHO_01769 2.6e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NPGFCMHO_01770 1.8e-159 S Protein of unknown function (DUF979)
NPGFCMHO_01771 2.3e-114 S Protein of unknown function (DUF969)
NPGFCMHO_01772 4.4e-240 G PTS system sugar-specific permease component
NPGFCMHO_01773 2.8e-271 G PTS system Galactitol-specific IIC component
NPGFCMHO_01774 2e-94 S Protein of unknown function (DUF1440)
NPGFCMHO_01775 9.1e-105 S CAAX protease self-immunity
NPGFCMHO_01776 6.2e-202 S DUF218 domain
NPGFCMHO_01777 0.0 macB_3 V ABC transporter, ATP-binding protein
NPGFCMHO_01778 1.7e-270 cydA 1.10.3.14 C ubiquinol oxidase
NPGFCMHO_01779 7.7e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NPGFCMHO_01780 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NPGFCMHO_01781 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NPGFCMHO_01782 1.1e-175 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NPGFCMHO_01783 3.1e-245 G Bacterial extracellular solute-binding protein
NPGFCMHO_01784 6.4e-168 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
NPGFCMHO_01785 1.6e-199 tcsA S ABC transporter substrate-binding protein PnrA-like
NPGFCMHO_01786 1.4e-177 fpaP 3.4.11.5 I Releases the N-terminal proline from various substrates
NPGFCMHO_01787 1.3e-195 blaA6 V Beta-lactamase
NPGFCMHO_01788 1.2e-261 pts29C 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPGFCMHO_01789 3e-159 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
NPGFCMHO_01790 6.9e-214 S Bacterial protein of unknown function (DUF871)
NPGFCMHO_01791 1.4e-152 S Putative esterase
NPGFCMHO_01792 1.5e-194 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NPGFCMHO_01793 2e-132 3.5.2.6 V Beta-lactamase enzyme family
NPGFCMHO_01794 3.7e-157 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NPGFCMHO_01795 8.4e-134 S membrane transporter protein
NPGFCMHO_01796 3e-18 S PD-(D/E)XK nuclease family transposase
NPGFCMHO_01797 4e-161 yeaE S Aldo/keto reductase family
NPGFCMHO_01798 1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPGFCMHO_01799 7.7e-120 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NPGFCMHO_01800 3.7e-125 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NPGFCMHO_01801 6e-238 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NPGFCMHO_01802 3e-232 pbuG S permease
NPGFCMHO_01804 7.4e-111 K helix_turn_helix, mercury resistance
NPGFCMHO_01805 2.3e-232 pbuG S permease
NPGFCMHO_01806 3.4e-46 I bis(5'-adenosyl)-triphosphatase activity
NPGFCMHO_01807 1.1e-226 pbuG S permease
NPGFCMHO_01808 3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NPGFCMHO_01809 4.1e-90
NPGFCMHO_01810 5.5e-90
NPGFCMHO_01811 1.4e-77 atkY K Penicillinase repressor
NPGFCMHO_01812 6.3e-66 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NPGFCMHO_01813 1.1e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NPGFCMHO_01814 0.0 copA 3.6.3.54 P P-type ATPase
NPGFCMHO_01815 4.4e-155 ropB K Helix-turn-helix XRE-family like proteins
NPGFCMHO_01816 0.0 pepO 3.4.24.71 O Peptidase family M13
NPGFCMHO_01817 4.1e-286 E Amino acid permease
NPGFCMHO_01818 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NPGFCMHO_01819 1e-248 ynbB 4.4.1.1 P aluminum resistance
NPGFCMHO_01820 2.3e-75 K Acetyltransferase (GNAT) domain
NPGFCMHO_01821 2.3e-232 EGP Sugar (and other) transporter
NPGFCMHO_01822 6.5e-69 S Iron-sulphur cluster biosynthesis
NPGFCMHO_01823 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPGFCMHO_01824 1.5e-115 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NPGFCMHO_01825 2.2e-107
NPGFCMHO_01826 2.6e-152 ropB K Transcriptional regulator
NPGFCMHO_01827 1.2e-201 EGP Major facilitator Superfamily
NPGFCMHO_01828 8.4e-290 clcA P chloride
NPGFCMHO_01829 6.6e-270 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPGFCMHO_01830 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NPGFCMHO_01831 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPGFCMHO_01832 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPGFCMHO_01833 3.7e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPGFCMHO_01834 1.7e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPGFCMHO_01835 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NPGFCMHO_01836 2e-163 repA S Replication initiator protein A
NPGFCMHO_01837 3.9e-44 relB L Addiction module antitoxin, RelB DinJ family
NPGFCMHO_01838 5.7e-86
NPGFCMHO_01839 8.9e-41
NPGFCMHO_01840 1.8e-22
NPGFCMHO_01841 0.0 traA L MobA MobL family protein
NPGFCMHO_01842 3.5e-79
NPGFCMHO_01843 8.4e-48 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPGFCMHO_01844 6.8e-43 hxlR K Transcriptional regulator, HxlR family
NPGFCMHO_01845 5.7e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NPGFCMHO_01846 0.0 M Cna protein B-type domain
NPGFCMHO_01848 3.3e-54 V efflux transmembrane transporter activity
NPGFCMHO_01849 8.7e-69
NPGFCMHO_01850 3.6e-131 3.6.1.13, 3.6.1.55 F NUDIX domain
NPGFCMHO_01851 3.6e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPGFCMHO_01852 3.2e-103 pncA Q Isochorismatase family
NPGFCMHO_01853 1.1e-18
NPGFCMHO_01854 5.5e-101 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NPGFCMHO_01855 2.9e-148 cbiO2 P ABC transporter
NPGFCMHO_01856 2.3e-156 P ABC transporter
NPGFCMHO_01857 9.7e-133 cbiQ P Cobalt transport protein
NPGFCMHO_01858 7e-91 2.7.7.65 T phosphorelay sensor kinase activity
NPGFCMHO_01859 6.4e-73 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NPGFCMHO_01860 2e-146 D CobQ CobB MinD ParA nucleotide binding domain protein
NPGFCMHO_01861 9.8e-36

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)