ORF_ID e_value Gene_name EC_number CAZy COGs Description
AAPGIAML_00001 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AAPGIAML_00002 7.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AAPGIAML_00003 1.1e-29 yyzM S Protein conserved in bacteria
AAPGIAML_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AAPGIAML_00005 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AAPGIAML_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AAPGIAML_00007 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
AAPGIAML_00008 3e-60 divIC D Septum formation initiator
AAPGIAML_00010 2.1e-233 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
AAPGIAML_00011 9.7e-236 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AAPGIAML_00012 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AAPGIAML_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AAPGIAML_00026 2.6e-10
AAPGIAML_00032 3.2e-94 mreC M Involved in formation and maintenance of cell shape
AAPGIAML_00033 9.7e-81 mreD M rod shape-determining protein MreD
AAPGIAML_00034 2.1e-83 usp 3.5.1.28 CBM50 S CHAP domain
AAPGIAML_00035 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AAPGIAML_00036 2.5e-217 araT 2.6.1.1 E Aminotransferase
AAPGIAML_00037 8e-140 recO L Involved in DNA repair and RecF pathway recombination
AAPGIAML_00038 2.7e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AAPGIAML_00039 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAPGIAML_00040 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AAPGIAML_00041 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AAPGIAML_00042 7.8e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AAPGIAML_00043 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AAPGIAML_00044 1.2e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AAPGIAML_00045 1.5e-291 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AAPGIAML_00046 4.2e-35 L reverse transcriptase
AAPGIAML_00047 1.9e-158 S CHAP domain
AAPGIAML_00048 1.6e-238 purD 6.3.4.13 F Belongs to the GARS family
AAPGIAML_00049 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AAPGIAML_00050 1.9e-200 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AAPGIAML_00051 1.9e-15 S NYN domain
AAPGIAML_00052 3.6e-71 S KAP family P-loop domain
AAPGIAML_00053 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AAPGIAML_00054 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AAPGIAML_00055 3.1e-69 argR K Regulates arginine biosynthesis genes
AAPGIAML_00056 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
AAPGIAML_00057 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AAPGIAML_00058 3e-78 S Protein of unknown function (DUF3021)
AAPGIAML_00059 9.3e-69 K LytTr DNA-binding domain
AAPGIAML_00061 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AAPGIAML_00063 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AAPGIAML_00064 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
AAPGIAML_00065 4e-229 cinA 3.5.1.42 S Belongs to the CinA family
AAPGIAML_00066 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AAPGIAML_00067 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
AAPGIAML_00073 2.6e-10
AAPGIAML_00076 1.9e-07
AAPGIAML_00081 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AAPGIAML_00082 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
AAPGIAML_00083 1.2e-35 XK27_02060 S Transglycosylase associated protein
AAPGIAML_00084 3.9e-72 badR K Transcriptional regulator, marr family
AAPGIAML_00085 3.2e-95 S reductase
AAPGIAML_00087 1.3e-287 ahpF O alkyl hydroperoxide reductase
AAPGIAML_00088 1.1e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
AAPGIAML_00089 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
AAPGIAML_00090 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AAPGIAML_00091 1.6e-82 S Putative small multi-drug export protein
AAPGIAML_00092 1.8e-75 ctsR K Belongs to the CtsR family
AAPGIAML_00093 0.0 clpC O Belongs to the ClpA ClpB family
AAPGIAML_00094 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AAPGIAML_00095 4.8e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AAPGIAML_00096 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
AAPGIAML_00097 4.7e-140 S SseB protein N-terminal domain
AAPGIAML_00098 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
AAPGIAML_00100 4e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AAPGIAML_00101 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AAPGIAML_00103 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAPGIAML_00104 1.3e-90 yacP S RNA-binding protein containing a PIN domain
AAPGIAML_00105 1.3e-151 degV S DegV family
AAPGIAML_00107 5.1e-22 K Transcriptional
AAPGIAML_00108 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AAPGIAML_00109 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
AAPGIAML_00110 4.1e-42 int2 L Belongs to the 'phage' integrase family
AAPGIAML_00111 2.2e-98 M1-798 K Rhodanese Homology Domain
AAPGIAML_00112 5.5e-47 trxA O Belongs to the thioredoxin family
AAPGIAML_00113 4.8e-160 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AAPGIAML_00115 9.9e-51 frnE Q DSBA-like thioredoxin domain
AAPGIAML_00116 9.6e-16 S Protein of unknown function (DUF1211)
AAPGIAML_00117 1.3e-17
AAPGIAML_00118 4.5e-29 K Helix-turn-helix domain
AAPGIAML_00120 8.6e-148 srtB 3.4.22.70 S Sortase family
AAPGIAML_00121 5.7e-233 capA M Bacterial capsule synthesis protein
AAPGIAML_00122 8e-39 gcvR T UPF0237 protein
AAPGIAML_00123 6.2e-241 XK27_08635 S UPF0210 protein
AAPGIAML_00124 7.3e-132 ais G Phosphoglycerate mutase
AAPGIAML_00125 1e-137 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
AAPGIAML_00126 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
AAPGIAML_00127 1.4e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AAPGIAML_00128 6.3e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AAPGIAML_00129 2.3e-302 dnaK O Heat shock 70 kDa protein
AAPGIAML_00130 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AAPGIAML_00131 5.9e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AAPGIAML_00132 1.8e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
AAPGIAML_00133 1.3e-79 hmpT S cog cog4720
AAPGIAML_00136 3.9e-87 sigH K DNA-templated transcription, initiation
AAPGIAML_00137 4e-139 ykuT M mechanosensitive ion channel
AAPGIAML_00138 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AAPGIAML_00139 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AAPGIAML_00140 1.1e-308 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AAPGIAML_00141 1.6e-82 XK27_03960 S Protein of unknown function (DUF3013)
AAPGIAML_00142 4.9e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
AAPGIAML_00143 2.2e-176 prmA J Ribosomal protein L11 methyltransferase
AAPGIAML_00144 2.4e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AAPGIAML_00145 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
AAPGIAML_00146 9.1e-83 nrdI F Belongs to the NrdI family
AAPGIAML_00147 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AAPGIAML_00148 4.4e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AAPGIAML_00149 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AAPGIAML_00150 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AAPGIAML_00151 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AAPGIAML_00152 3.4e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
AAPGIAML_00153 1.6e-189 yhjX P Major Facilitator
AAPGIAML_00154 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AAPGIAML_00155 7.1e-72 V VanZ like family
AAPGIAML_00156 4.9e-178 D nuclear chromosome segregation
AAPGIAML_00157 1e-123 glnQ E abc transporter atp-binding protein
AAPGIAML_00158 1.1e-270 glnP P ABC transporter
AAPGIAML_00159 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AAPGIAML_00160 2.4e-17 S Protein of unknown function (DUF3021)
AAPGIAML_00161 1.6e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
AAPGIAML_00162 8.7e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
AAPGIAML_00163 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
AAPGIAML_00164 7.7e-233 sufD O assembly protein SufD
AAPGIAML_00165 1.1e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AAPGIAML_00166 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
AAPGIAML_00167 2.9e-273 sufB O assembly protein SufB
AAPGIAML_00168 4.7e-26
AAPGIAML_00169 1e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AAPGIAML_00170 6.2e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AAPGIAML_00171 3.5e-71 adcR K transcriptional
AAPGIAML_00172 5.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
AAPGIAML_00173 5.6e-128 adcB P ABC transporter (Permease
AAPGIAML_00174 9e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
AAPGIAML_00175 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AAPGIAML_00176 3.1e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
AAPGIAML_00177 8.1e-257 pgi 5.3.1.9 G Belongs to the GPI family
AAPGIAML_00178 1.8e-148 Z012_04635 K sequence-specific DNA binding
AAPGIAML_00179 1.5e-281 V ABC transporter
AAPGIAML_00180 6.1e-126 yeeN K transcriptional regulatory protein
AAPGIAML_00181 5.9e-47 yajC U protein transport
AAPGIAML_00182 2e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AAPGIAML_00183 7.2e-144 cdsA 2.7.7.41 S Belongs to the CDS family
AAPGIAML_00184 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
AAPGIAML_00185 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AAPGIAML_00186 0.0 WQ51_06230 S ABC transporter substrate binding protein
AAPGIAML_00187 1.4e-142 cmpC S abc transporter atp-binding protein
AAPGIAML_00188 1.9e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AAPGIAML_00189 1.2e-286 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AAPGIAML_00191 7.2e-44
AAPGIAML_00192 1.4e-53 S TM2 domain
AAPGIAML_00193 5.2e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AAPGIAML_00194 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AAPGIAML_00195 1.4e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AAPGIAML_00196 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
AAPGIAML_00197 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
AAPGIAML_00198 8.4e-63 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
AAPGIAML_00199 4e-142 cof S Sucrose-6F-phosphate phosphohydrolase
AAPGIAML_00200 6.9e-136 glcR K transcriptional regulator (DeoR family)
AAPGIAML_00201 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AAPGIAML_00202 1.1e-223 L Transposase
AAPGIAML_00203 6.8e-37 yjdF S Protein of unknown function (DUF2992)
AAPGIAML_00204 4.3e-150 cylA V abc transporter atp-binding protein
AAPGIAML_00205 3.5e-125 cylB V ABC-2 type transporter
AAPGIAML_00206 9e-75 K COG3279 Response regulator of the LytR AlgR family
AAPGIAML_00207 8.9e-32 S Protein of unknown function (DUF3021)
AAPGIAML_00208 9.6e-124 mta K Transcriptional
AAPGIAML_00209 4.7e-120 yhcA V abc transporter atp-binding protein
AAPGIAML_00210 7.9e-217 macB_2 V FtsX-like permease family
AAPGIAML_00211 2.8e-271 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AAPGIAML_00212 4.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AAPGIAML_00213 2.6e-71 yhaI S Protein of unknown function (DUF805)
AAPGIAML_00214 5.8e-255 pepC 3.4.22.40 E aminopeptidase
AAPGIAML_00215 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AAPGIAML_00216 1.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AAPGIAML_00217 5.8e-94 ypsA S Belongs to the UPF0398 family
AAPGIAML_00218 2.1e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AAPGIAML_00219 1.9e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AAPGIAML_00220 9.8e-275 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
AAPGIAML_00221 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
AAPGIAML_00222 4.8e-22
AAPGIAML_00223 5.2e-256 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AAPGIAML_00224 1.5e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
AAPGIAML_00225 7.1e-302 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AAPGIAML_00226 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AAPGIAML_00227 1.7e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AAPGIAML_00228 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AAPGIAML_00229 1.5e-127 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AAPGIAML_00230 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
AAPGIAML_00231 5.9e-102 ybhL S Belongs to the BI1 family
AAPGIAML_00232 5.5e-12 ycdA S Domain of unknown function (DUF4352)
AAPGIAML_00233 2.4e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AAPGIAML_00234 1.8e-90 K transcriptional regulator
AAPGIAML_00235 1.6e-36 yneF S UPF0154 protein
AAPGIAML_00236 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AAPGIAML_00237 3.6e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AAPGIAML_00238 5.1e-98 XK27_09740 S Phosphoesterase
AAPGIAML_00239 8.3e-87 ykuL S CBS domain
AAPGIAML_00240 1.8e-131 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
AAPGIAML_00241 7.6e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AAPGIAML_00242 2.6e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AAPGIAML_00243 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AAPGIAML_00244 4.4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AAPGIAML_00245 7.9e-258 trkH P Cation transport protein
AAPGIAML_00246 7.2e-245 trkA P Potassium transporter peripheral membrane component
AAPGIAML_00247 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AAPGIAML_00248 5.6e-87 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AAPGIAML_00249 1.1e-89 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
AAPGIAML_00250 2.7e-155 K sequence-specific DNA binding
AAPGIAML_00251 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
AAPGIAML_00252 3.2e-53 yhaI L Membrane
AAPGIAML_00253 1.3e-241 S Domain of unknown function (DUF4173)
AAPGIAML_00254 6.8e-95 ureI S AmiS/UreI family transporter
AAPGIAML_00255 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
AAPGIAML_00256 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
AAPGIAML_00257 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
AAPGIAML_00258 6.6e-78 ureE O enzyme active site formation
AAPGIAML_00259 1.7e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AAPGIAML_00260 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AAPGIAML_00261 6.4e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
AAPGIAML_00262 2.1e-177 cbiM P PDGLE domain
AAPGIAML_00263 2.9e-137 P cobalt transport protein
AAPGIAML_00264 6.3e-131 cbiO P ABC transporter
AAPGIAML_00265 6.3e-138 ET ABC transporter substrate-binding protein
AAPGIAML_00266 9.2e-164 metQ M Belongs to the NlpA lipoprotein family
AAPGIAML_00267 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
AAPGIAML_00268 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AAPGIAML_00269 1.2e-99 metI P ABC transporter (Permease
AAPGIAML_00270 1.9e-209 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AAPGIAML_00271 3.5e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
AAPGIAML_00272 3e-93 S UPF0397 protein
AAPGIAML_00273 3.5e-310 ykoD P abc transporter atp-binding protein
AAPGIAML_00274 4.5e-149 cbiQ P cobalt transport
AAPGIAML_00275 1.8e-119 ktrA P COG0569 K transport systems, NAD-binding component
AAPGIAML_00276 4.7e-236 P COG0168 Trk-type K transport systems, membrane components
AAPGIAML_00277 1.5e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
AAPGIAML_00278 6.2e-91 yceD K metal-binding, possibly nucleic acid-binding protein
AAPGIAML_00279 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AAPGIAML_00280 5.9e-280 T PhoQ Sensor
AAPGIAML_00281 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AAPGIAML_00282 1.7e-213 dnaB L Replication initiation and membrane attachment
AAPGIAML_00283 4.4e-166 dnaI L Primosomal protein DnaI
AAPGIAML_00284 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AAPGIAML_00285 1.5e-112
AAPGIAML_00286 6.2e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AAPGIAML_00287 2.5e-62 manO S protein conserved in bacteria
AAPGIAML_00288 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
AAPGIAML_00289 2e-117 manM G pts system
AAPGIAML_00290 4.9e-174 manL 2.7.1.191 G pts system
AAPGIAML_00291 2e-67 manO S Protein conserved in bacteria
AAPGIAML_00292 2.7e-163 manN G PTS system mannose fructose sorbose family IID component
AAPGIAML_00293 6.1e-135 manY G pts system
AAPGIAML_00294 8.1e-169 manL 2.7.1.191 G pts system
AAPGIAML_00295 9.3e-138 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
AAPGIAML_00296 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
AAPGIAML_00297 6.2e-247 pbuO S permease
AAPGIAML_00298 1.2e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
AAPGIAML_00299 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
AAPGIAML_00300 9.8e-188 brpA K Transcriptional
AAPGIAML_00301 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
AAPGIAML_00302 4e-199 nusA K Participates in both transcription termination and antitermination
AAPGIAML_00303 2.3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
AAPGIAML_00304 1.4e-41 ylxQ J ribosomal protein
AAPGIAML_00305 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AAPGIAML_00306 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AAPGIAML_00307 2.2e-99 yvdD 3.2.2.10 S Belongs to the LOG family
AAPGIAML_00308 1.5e-188 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
AAPGIAML_00309 3.1e-270 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AAPGIAML_00310 3.8e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
AAPGIAML_00311 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
AAPGIAML_00312 1.7e-199 metB 2.5.1.48, 4.4.1.8 E cystathionine
AAPGIAML_00313 2.3e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
AAPGIAML_00314 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
AAPGIAML_00315 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
AAPGIAML_00316 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AAPGIAML_00317 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AAPGIAML_00318 6.4e-73 ylbF S Belongs to the UPF0342 family
AAPGIAML_00319 1.9e-46 ylbG S UPF0298 protein
AAPGIAML_00320 2.6e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
AAPGIAML_00321 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
AAPGIAML_00322 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
AAPGIAML_00323 4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
AAPGIAML_00324 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
AAPGIAML_00325 6.6e-111 acuB S CBS domain
AAPGIAML_00326 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AAPGIAML_00327 2.2e-108 yvyE 3.4.13.9 S YigZ family
AAPGIAML_00328 2.4e-237 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AAPGIAML_00329 1.3e-98 comFC K competence protein
AAPGIAML_00330 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AAPGIAML_00338 6.6e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
AAPGIAML_00339 1.6e-103 S Domain of unknown function (DUF1803)
AAPGIAML_00340 7.8e-102 ygaC J Belongs to the UPF0374 family
AAPGIAML_00341 8.3e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
AAPGIAML_00342 3.8e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AAPGIAML_00343 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
AAPGIAML_00344 6.9e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
AAPGIAML_00345 1.8e-113 S HAD hydrolase, family IA, variant 3
AAPGIAML_00346 2.1e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
AAPGIAML_00347 5.2e-72 marR K Transcriptional regulator, MarR family
AAPGIAML_00348 1.4e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AAPGIAML_00349 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AAPGIAML_00350 4.4e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
AAPGIAML_00351 3.6e-163 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
AAPGIAML_00352 6.2e-126 IQ reductase
AAPGIAML_00353 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AAPGIAML_00354 5.2e-52 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AAPGIAML_00355 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AAPGIAML_00356 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
AAPGIAML_00357 1e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AAPGIAML_00358 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
AAPGIAML_00359 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AAPGIAML_00360 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
AAPGIAML_00361 1.4e-112 fruR K transcriptional
AAPGIAML_00362 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AAPGIAML_00363 0.0 fruA 2.7.1.202 G phosphotransferase system
AAPGIAML_00364 7.9e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAPGIAML_00365 7.1e-231 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AAPGIAML_00367 4.4e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
AAPGIAML_00368 4.8e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AAPGIAML_00369 3.9e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AAPGIAML_00370 4.8e-254 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
AAPGIAML_00371 4.2e-87 2.3.1.128 K acetyltransferase
AAPGIAML_00372 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
AAPGIAML_00373 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AAPGIAML_00374 1.1e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AAPGIAML_00375 5e-63 WQ51_03320 S cog cog4835
AAPGIAML_00376 2.8e-146 XK27_08360 S EDD domain protein, DegV family
AAPGIAML_00377 5.7e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AAPGIAML_00378 4.8e-216 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AAPGIAML_00379 0.0 yfmR S abc transporter atp-binding protein
AAPGIAML_00380 1.3e-26 U response to pH
AAPGIAML_00381 1.1e-114 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
AAPGIAML_00382 8.8e-209 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
AAPGIAML_00383 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
AAPGIAML_00384 5.2e-282 S Psort location CytoplasmicMembrane, score
AAPGIAML_00385 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
AAPGIAML_00386 1.7e-73 K DNA-binding transcription factor activity
AAPGIAML_00387 0.0 lmrA1 V abc transporter atp-binding protein
AAPGIAML_00388 0.0 lmrA2 V abc transporter atp-binding protein
AAPGIAML_00389 4.3e-112 K Acetyltransferase (GNAT) family
AAPGIAML_00390 5.7e-112 2.7.6.5 S Region found in RelA / SpoT proteins
AAPGIAML_00391 8.3e-117 T response regulator
AAPGIAML_00392 1.2e-214 sptS 2.7.13.3 T Histidine kinase
AAPGIAML_00393 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AAPGIAML_00394 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AAPGIAML_00395 4.5e-160 cvfB S Protein conserved in bacteria
AAPGIAML_00396 3.7e-34 yozE S Belongs to the UPF0346 family
AAPGIAML_00397 1.3e-123 sip M LysM domain protein
AAPGIAML_00398 5.2e-190 phoH T phosphate starvation-inducible protein PhoH
AAPGIAML_00402 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AAPGIAML_00403 4.4e-160 S reductase
AAPGIAML_00404 4.7e-168 K transcriptional regulator (lysR family)
AAPGIAML_00405 4e-104 S CAAX amino terminal protease family protein
AAPGIAML_00406 7.8e-277 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AAPGIAML_00407 4.5e-169 coiA 3.6.4.12 S Competence protein
AAPGIAML_00408 0.0 pepF E oligoendopeptidase F
AAPGIAML_00409 4.2e-212 oxlT P COG0477 Permeases of the major facilitator superfamily
AAPGIAML_00410 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
AAPGIAML_00411 5.6e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
AAPGIAML_00412 1.7e-57 yxjI S LURP-one-related
AAPGIAML_00413 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AAPGIAML_00414 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
AAPGIAML_00415 3.2e-145 L Integrase core domain protein
AAPGIAML_00416 5.9e-123 L Helix-turn-helix domain
AAPGIAML_00417 2e-132 agrA KT phosphorelay signal transduction system
AAPGIAML_00418 6.4e-230 2.7.13.3 T GHKL domain
AAPGIAML_00419 1.5e-14
AAPGIAML_00420 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
AAPGIAML_00421 4e-139 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AAPGIAML_00422 2.2e-221 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
AAPGIAML_00423 2.2e-182 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AAPGIAML_00424 7.3e-217 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AAPGIAML_00425 2.2e-123 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
AAPGIAML_00426 4.3e-203 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
AAPGIAML_00427 1e-127 yxkH G deacetylase
AAPGIAML_00428 5.8e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
AAPGIAML_00429 4.5e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AAPGIAML_00430 4.4e-150 rarD S Transporter
AAPGIAML_00431 2.2e-15 T peptidase
AAPGIAML_00432 3e-14 coiA 3.6.4.12 S Competence protein
AAPGIAML_00433 3.4e-103 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AAPGIAML_00434 5.8e-100 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AAPGIAML_00435 2.1e-97 F Shikimate kinase
AAPGIAML_00436 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AAPGIAML_00438 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAPGIAML_00439 9e-122 atpB C it plays a direct role in the translocation of protons across the membrane
AAPGIAML_00440 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AAPGIAML_00441 8.7e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AAPGIAML_00442 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AAPGIAML_00443 4.8e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AAPGIAML_00444 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AAPGIAML_00445 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AAPGIAML_00446 2.1e-217 ftsW D Belongs to the SEDS family
AAPGIAML_00447 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AAPGIAML_00448 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AAPGIAML_00449 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AAPGIAML_00451 6.3e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AAPGIAML_00452 1.7e-159 holB 2.7.7.7 L dna polymerase iii
AAPGIAML_00453 7.5e-133 yaaT S stage 0 sporulation protein
AAPGIAML_00454 1.2e-54 yabA L Involved in initiation control of chromosome replication
AAPGIAML_00455 3.6e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AAPGIAML_00456 2.1e-227 amt P Ammonium Transporter
AAPGIAML_00457 7.3e-53 glnB K Belongs to the P(II) protein family
AAPGIAML_00458 1.3e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
AAPGIAML_00459 1e-140 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
AAPGIAML_00460 2e-81 S Bacterial inner membrane protein
AAPGIAML_00461 6.1e-114 3.4.17.14, 3.5.1.28 NU amidase activity
AAPGIAML_00462 3.5e-294 nptA P COG1283 Na phosphate symporter
AAPGIAML_00463 4.4e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AAPGIAML_00464 6.6e-221 S membrane
AAPGIAML_00465 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AAPGIAML_00466 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AAPGIAML_00467 1.7e-38 ynzC S UPF0291 protein
AAPGIAML_00468 8.7e-254 cycA E permease
AAPGIAML_00469 2.9e-10 uvrX 2.7.7.7 L impB/mucB/samB family
AAPGIAML_00470 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AAPGIAML_00471 1.3e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AAPGIAML_00474 1.4e-67 K Helix-turn-helix
AAPGIAML_00475 1.3e-43
AAPGIAML_00477 4e-167 fhuR K transcriptional regulator (lysR family)
AAPGIAML_00478 8.3e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AAPGIAML_00479 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AAPGIAML_00480 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AAPGIAML_00481 1.8e-221 pyrP F uracil Permease
AAPGIAML_00482 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AAPGIAML_00483 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
AAPGIAML_00484 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
AAPGIAML_00485 1.5e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
AAPGIAML_00486 9.8e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AAPGIAML_00487 5.8e-121 macB V ABC transporter, ATP-binding protein
AAPGIAML_00488 6.5e-213 V permease protein
AAPGIAML_00489 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AAPGIAML_00490 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AAPGIAML_00493 6.8e-104 XK27_00530 M CHAP domain protein
AAPGIAML_00494 9.9e-106 abiGI K Transcriptional regulator, AbiEi antitoxin
AAPGIAML_00495 1.2e-272 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
AAPGIAML_00496 0.0 mdlB V abc transporter atp-binding protein
AAPGIAML_00497 0.0 lmrA V abc transporter atp-binding protein
AAPGIAML_00498 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AAPGIAML_00499 6.8e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AAPGIAML_00500 2.4e-51 S Protein conserved in bacteria
AAPGIAML_00501 1.5e-196 yceA S Belongs to the UPF0176 family
AAPGIAML_00502 3.9e-114 S VIT family
AAPGIAML_00503 4e-139 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AAPGIAML_00504 4.4e-219 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
AAPGIAML_00505 3.4e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
AAPGIAML_00507 1e-145 E Alpha beta hydrolase
AAPGIAML_00508 1.3e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AAPGIAML_00509 7.9e-152 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
AAPGIAML_00510 5.1e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
AAPGIAML_00511 1.1e-178 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
AAPGIAML_00512 2.3e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AAPGIAML_00513 3.7e-87 L COG1943 Transposase and inactivated derivatives
AAPGIAML_00514 3.2e-145 L Integrase core domain protein
AAPGIAML_00515 5.9e-123 L Helix-turn-helix domain
AAPGIAML_00516 8.9e-84 V ABC transporter, ATP-binding protein
AAPGIAML_00517 1.2e-42 V ABC transporter, ATP-binding protein
AAPGIAML_00518 4.8e-54 S ABC-2 family transporter protein
AAPGIAML_00519 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
AAPGIAML_00520 1.1e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AAPGIAML_00521 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
AAPGIAML_00522 4.6e-23
AAPGIAML_00523 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AAPGIAML_00524 0.0 U protein secretion
AAPGIAML_00525 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
AAPGIAML_00526 1.3e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
AAPGIAML_00527 1.1e-12
AAPGIAML_00528 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AAPGIAML_00529 6.5e-152 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AAPGIAML_00530 1.3e-193 S Protein of unknown function (DUF3114)
AAPGIAML_00531 4.1e-29 pspC KT PspC domain protein
AAPGIAML_00532 5.2e-119 yqfA K protein, Hemolysin III
AAPGIAML_00533 3e-78 K hmm pf08876
AAPGIAML_00534 1e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
AAPGIAML_00535 4.9e-210 mvaS 2.3.3.10 I synthase
AAPGIAML_00536 1.1e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AAPGIAML_00537 8.4e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AAPGIAML_00538 9.7e-22
AAPGIAML_00539 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AAPGIAML_00540 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
AAPGIAML_00541 2.2e-23 mmuP E amino acid
AAPGIAML_00542 1.7e-213 mmuP E amino acid
AAPGIAML_00543 5.3e-162 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
AAPGIAML_00544 1.3e-30 S Domain of unknown function (DUF1912)
AAPGIAML_00545 2.1e-13 L Helix-hairpin-helix DNA-binding motif class 1
AAPGIAML_00546 8.2e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AAPGIAML_00547 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AAPGIAML_00549 9.6e-12
AAPGIAML_00550 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AAPGIAML_00551 3.4e-199 ilvE 2.6.1.42 E Aminotransferase
AAPGIAML_00552 4.8e-16 S Protein of unknown function (DUF2969)
AAPGIAML_00555 1.2e-203 rpsA 1.17.7.4 J ribosomal protein S1
AAPGIAML_00558 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
AAPGIAML_00559 1.3e-117 M Pfam SNARE associated Golgi protein
AAPGIAML_00560 1.7e-229 murN 2.3.2.16 V FemAB family
AAPGIAML_00561 5.8e-172 S oxidoreductase
AAPGIAML_00562 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
AAPGIAML_00563 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
AAPGIAML_00564 0.0 clpE O Belongs to the ClpA ClpB family
AAPGIAML_00565 4.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AAPGIAML_00566 1.1e-33 ykuJ S protein conserved in bacteria
AAPGIAML_00567 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
AAPGIAML_00568 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
AAPGIAML_00569 9.1e-78 feoA P FeoA domain protein
AAPGIAML_00570 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
AAPGIAML_00571 6.6e-08
AAPGIAML_00572 3.5e-151 I Alpha/beta hydrolase family
AAPGIAML_00573 2e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AAPGIAML_00574 1.2e-146 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AAPGIAML_00575 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
AAPGIAML_00576 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AAPGIAML_00577 7.1e-150 licT K antiterminator
AAPGIAML_00578 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AAPGIAML_00579 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
AAPGIAML_00580 8.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AAPGIAML_00581 2.4e-150 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AAPGIAML_00582 1.7e-97 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AAPGIAML_00583 1.6e-219 mdtG EGP Major facilitator Superfamily
AAPGIAML_00584 2e-33 secG U Preprotein translocase subunit SecG
AAPGIAML_00585 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AAPGIAML_00586 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
AAPGIAML_00587 6.9e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AAPGIAML_00588 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
AAPGIAML_00589 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
AAPGIAML_00590 1.2e-180 ccpA K Catabolite control protein A
AAPGIAML_00591 1.2e-202 yyaQ S YjbR
AAPGIAML_00592 1.4e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AAPGIAML_00593 3.1e-75 yueI S Protein of unknown function (DUF1694)
AAPGIAML_00594 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AAPGIAML_00595 2.7e-25 WQ51_00785
AAPGIAML_00596 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AAPGIAML_00597 1.4e-217 ywbD 2.1.1.191 J Methyltransferase
AAPGIAML_00598 3.7e-117 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AAPGIAML_00599 6.3e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AAPGIAML_00600 5.9e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AAPGIAML_00601 2.2e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AAPGIAML_00602 4.1e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
AAPGIAML_00603 4.2e-53 yheA S Belongs to the UPF0342 family
AAPGIAML_00604 5.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
AAPGIAML_00605 1.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AAPGIAML_00606 4.5e-80 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AAPGIAML_00607 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
AAPGIAML_00608 5e-249 msrR K Transcriptional regulator
AAPGIAML_00609 2.5e-151 ydiA P C4-dicarboxylate transporter malic acid transport
AAPGIAML_00610 1.9e-200 I acyl-CoA dehydrogenase
AAPGIAML_00611 2.7e-97 mip S hydroperoxide reductase activity
AAPGIAML_00612 1e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AAPGIAML_00613 4.3e-22
AAPGIAML_00614 2e-217 EGP Transmembrane secretion effector
AAPGIAML_00615 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
AAPGIAML_00616 1.1e-49
AAPGIAML_00617 8.7e-60
AAPGIAML_00618 5.9e-55
AAPGIAML_00619 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AAPGIAML_00620 5.1e-78 P Mediates zinc uptake. May also transport other divalent cations
AAPGIAML_00621 1.1e-51 zupT P Mediates zinc uptake. May also transport other divalent cations
AAPGIAML_00622 1.6e-61 smtB K Transcriptional regulator
AAPGIAML_00623 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
AAPGIAML_00625 6.1e-140 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AAPGIAML_00626 5.8e-132 S Domain of unknown function (DUF4336)
AAPGIAML_00627 7e-204 yeaN P transporter
AAPGIAML_00628 4.2e-150 yitS S EDD domain protein, DegV family
AAPGIAML_00629 5.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
AAPGIAML_00630 2.7e-109 cutC P Participates in the control of copper homeostasis
AAPGIAML_00632 4.1e-21 S Domain of unknown function (DUF4767)
AAPGIAML_00633 1.3e-151 S Domain of unknown function (DUF4300)
AAPGIAML_00634 1.2e-113 V CAAX protease self-immunity
AAPGIAML_00635 3.6e-159 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AAPGIAML_00636 9.8e-135 fecE 3.6.3.34 HP ABC transporter
AAPGIAML_00637 7.7e-175 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
AAPGIAML_00638 3.4e-126 ybbA S Putative esterase
AAPGIAML_00639 1.3e-157 yegS 2.7.1.107 I Diacylglycerol kinase
AAPGIAML_00640 2.3e-171 S Domain of unknown function (DUF389)
AAPGIAML_00641 5.5e-31 S Membrane
AAPGIAML_00642 7.8e-10 S CsbD-like
AAPGIAML_00643 7.3e-173 pdhD 1.8.1.4 C Dehydrogenase
AAPGIAML_00644 8.1e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
AAPGIAML_00645 4.6e-175 acoB C dehydrogenase E1 component
AAPGIAML_00646 3e-141 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AAPGIAML_00647 2.2e-48
AAPGIAML_00648 1.7e-126 V CAAX protease self-immunity
AAPGIAML_00649 2.6e-10
AAPGIAML_00650 6.5e-19 M Bacterial lipoprotein
AAPGIAML_00651 2.4e-60 S Protein of unknown function (DUF1722)
AAPGIAML_00652 2.4e-62 yqeB S Pyrimidine dimer DNA glycosylase
AAPGIAML_00654 5e-52
AAPGIAML_00655 4.1e-99 S CAAX protease self-immunity
AAPGIAML_00656 2.1e-122 estA E GDSL-like Lipase/Acylhydrolase
AAPGIAML_00657 6.2e-103
AAPGIAML_00658 3.1e-249 sulP P Sulfate permease and related transporters (MFS superfamily)
AAPGIAML_00659 4.9e-148 ycgQ S TIGR03943 family
AAPGIAML_00660 2.4e-156 XK27_03015 S permease
AAPGIAML_00662 0.0 yhgF K Transcriptional accessory protein
AAPGIAML_00663 2.2e-41 pspC KT PspC domain
AAPGIAML_00664 1.1e-167 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AAPGIAML_00665 2.6e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AAPGIAML_00666 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AAPGIAML_00667 8.5e-70 ytxH S General stress protein
AAPGIAML_00669 6.8e-178 yegQ O Peptidase U32
AAPGIAML_00670 1.7e-251 yegQ O Peptidase U32
AAPGIAML_00671 8.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
AAPGIAML_00672 3.2e-87 bioY S biotin synthase
AAPGIAML_00674 1.1e-33 XK27_12190 S protein conserved in bacteria
AAPGIAML_00675 2.4e-232 mntH P H( )-stimulated, divalent metal cation uptake system
AAPGIAML_00676 4.8e-11
AAPGIAML_00677 1.6e-64 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
AAPGIAML_00678 0.0 L helicase
AAPGIAML_00679 3.7e-14
AAPGIAML_00680 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AAPGIAML_00681 4.8e-137 M LysM domain
AAPGIAML_00682 8.4e-23
AAPGIAML_00683 5.2e-175 S hydrolase
AAPGIAML_00685 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
AAPGIAML_00686 6.7e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AAPGIAML_00687 3.5e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
AAPGIAML_00688 1.3e-26 P Hemerythrin HHE cation binding domain protein
AAPGIAML_00689 4.7e-154 5.2.1.8 G hydrolase
AAPGIAML_00690 2.6e-104 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAPGIAML_00691 2.6e-211 MA20_36090 S Protein of unknown function (DUF2974)
AAPGIAML_00692 6.7e-131 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AAPGIAML_00694 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
AAPGIAML_00695 3.6e-165 S Bacteriophage abortive infection AbiH
AAPGIAML_00697 3.8e-130 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
AAPGIAML_00698 2.2e-152 E Psort location Cytoplasmic, score
AAPGIAML_00699 1e-42 K Helix-turn-helix domain
AAPGIAML_00700 2.3e-303 hsdM 2.1.1.72 V type I restriction-modification system
AAPGIAML_00701 2.2e-136 S double-stranded DNA endodeoxyribonuclease activity
AAPGIAML_00702 0.0 2.4.1.21 GT5 M Right handed beta helix region
AAPGIAML_00703 1.2e-172 spd F DNA RNA non-specific endonuclease
AAPGIAML_00704 7.7e-92 lemA S LemA family
AAPGIAML_00705 1.3e-133 htpX O Belongs to the peptidase M48B family
AAPGIAML_00706 3.9e-116 sirR K iron dependent repressor
AAPGIAML_00707 9.5e-172 sitA P Belongs to the bacterial solute-binding protein 9 family
AAPGIAML_00708 8.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
AAPGIAML_00709 5.6e-127 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
AAPGIAML_00710 2.1e-74 S Psort location CytoplasmicMembrane, score
AAPGIAML_00711 1.8e-63 S Domain of unknown function (DUF4430)
AAPGIAML_00712 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AAPGIAML_00713 1.6e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
AAPGIAML_00714 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
AAPGIAML_00715 1.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
AAPGIAML_00716 2.7e-104 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
AAPGIAML_00717 1.1e-89 dps P Belongs to the Dps family
AAPGIAML_00718 3.4e-79 perR P Belongs to the Fur family
AAPGIAML_00719 7.1e-27 yqgQ S protein conserved in bacteria
AAPGIAML_00720 1e-176 glk 2.7.1.2 G Glucokinase
AAPGIAML_00721 0.0 typA T GTP-binding protein TypA
AAPGIAML_00723 6.7e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AAPGIAML_00724 4.7e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AAPGIAML_00725 6.5e-130 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AAPGIAML_00726 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AAPGIAML_00727 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AAPGIAML_00728 1.5e-121 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AAPGIAML_00729 2.2e-86 sepF D cell septum assembly
AAPGIAML_00730 5e-30 yggT D integral membrane protein
AAPGIAML_00731 6.5e-145 ylmH S conserved protein, contains S4-like domain
AAPGIAML_00732 8.4e-138 divIVA D Cell division initiation protein
AAPGIAML_00733 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AAPGIAML_00734 2.5e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAPGIAML_00735 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AAPGIAML_00736 6.5e-34 nrdH O Glutaredoxin
AAPGIAML_00737 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AAPGIAML_00738 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
AAPGIAML_00739 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
AAPGIAML_00740 3e-38 ptsH G phosphocarrier protein Hpr
AAPGIAML_00741 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AAPGIAML_00742 1.9e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
AAPGIAML_00743 6.1e-162 XK27_05670 S Putative esterase
AAPGIAML_00744 2.7e-153 XK27_05675 S Esterase
AAPGIAML_00745 3.5e-224 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
AAPGIAML_00746 1.8e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
AAPGIAML_00747 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
AAPGIAML_00748 0.0 uup S abc transporter atp-binding protein
AAPGIAML_00749 1.6e-39 MA20_06245 S yiaA/B two helix domain
AAPGIAML_00750 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
AAPGIAML_00751 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AAPGIAML_00752 1.3e-148 cobQ S glutamine amidotransferase
AAPGIAML_00753 2.7e-252 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
AAPGIAML_00754 7.9e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AAPGIAML_00755 1.1e-162 ybbR S Protein conserved in bacteria
AAPGIAML_00756 3.1e-248 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AAPGIAML_00757 1.3e-64 gtrA S GtrA-like protein
AAPGIAML_00758 4e-119 trmK 2.1.1.217 S SAM-dependent methyltransferase
AAPGIAML_00759 1.7e-142 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AAPGIAML_00760 1.1e-142 zupT P Mediates zinc uptake. May also transport other divalent cations
AAPGIAML_00761 7.4e-200 yurR 1.4.5.1 E oxidoreductase
AAPGIAML_00762 1.9e-258 S phospholipase Carboxylesterase
AAPGIAML_00763 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AAPGIAML_00764 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
AAPGIAML_00765 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AAPGIAML_00767 2.2e-30 KT response to antibiotic
AAPGIAML_00768 3.2e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
AAPGIAML_00769 2.4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
AAPGIAML_00770 3e-139 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AAPGIAML_00771 2.1e-117 ylfI S tigr01906
AAPGIAML_00772 1.3e-134 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
AAPGIAML_00773 4.7e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
AAPGIAML_00774 2.7e-59 XK27_08085
AAPGIAML_00775 7.2e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AAPGIAML_00776 1.5e-180 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AAPGIAML_00777 8e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AAPGIAML_00778 3e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AAPGIAML_00779 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
AAPGIAML_00780 6.1e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AAPGIAML_00781 4.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AAPGIAML_00782 4.7e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AAPGIAML_00783 1e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AAPGIAML_00784 9.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
AAPGIAML_00785 3.6e-19
AAPGIAML_00786 9e-95 XK27_05505 S Psort location CytoplasmicMembrane, score
AAPGIAML_00787 1.1e-144 P molecular chaperone
AAPGIAML_00788 9.3e-82 S Carbohydrate-binding domain-containing protein Cthe_2159
AAPGIAML_00789 7e-176 XK27_08075 M glycosyl transferase family 2
AAPGIAML_00790 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AAPGIAML_00791 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AAPGIAML_00792 2.6e-42 S Sugar efflux transporter for intercellular exchange
AAPGIAML_00793 5.2e-80 tag 3.2.2.20 L glycosylase
AAPGIAML_00794 1.1e-51 L High confidence in function and specificity
AAPGIAML_00795 6.8e-111 L High confidence in function and specificity
AAPGIAML_00796 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AAPGIAML_00797 3.2e-227 rodA D Belongs to the SEDS family
AAPGIAML_00798 1e-243 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AAPGIAML_00799 1.5e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
AAPGIAML_00800 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AAPGIAML_00801 1.6e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AAPGIAML_00802 1.2e-65 GnaT 2.5.1.16 K acetyltransferase
AAPGIAML_00803 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
AAPGIAML_00804 1.7e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AAPGIAML_00805 1.1e-180 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AAPGIAML_00806 6.5e-125 dnaD
AAPGIAML_00807 3.8e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AAPGIAML_00809 1.5e-231 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AAPGIAML_00810 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AAPGIAML_00811 2.6e-155 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AAPGIAML_00812 2.2e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
AAPGIAML_00813 8.3e-73 argR K Regulates arginine biosynthesis genes
AAPGIAML_00814 3e-301 recN L May be involved in recombinational repair of damaged DNA
AAPGIAML_00815 1.7e-148 DegV S DegV family
AAPGIAML_00816 2.2e-154 ypmR E COG2755 Lysophospholipase L1 and related esterases
AAPGIAML_00817 3.4e-95 ypmS S Protein conserved in bacteria
AAPGIAML_00818 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AAPGIAML_00820 8.9e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
AAPGIAML_00821 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AAPGIAML_00822 2.1e-288 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AAPGIAML_00823 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
AAPGIAML_00824 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AAPGIAML_00825 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AAPGIAML_00826 0.0 dnaE 2.7.7.7 L DNA polymerase
AAPGIAML_00827 1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AAPGIAML_00828 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AAPGIAML_00829 0.0 Q the current gene model (or a revised gene model) may contain a frame shift
AAPGIAML_00830 1.3e-18 S Domain of unknown function (DUF4649)
AAPGIAML_00831 1.1e-176 XK27_08835 S ABC transporter substrate binding protein
AAPGIAML_00832 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
AAPGIAML_00833 7.6e-135 XK27_08845 S abc transporter atp-binding protein
AAPGIAML_00834 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AAPGIAML_00835 9.5e-149 estA CE1 S Esterase
AAPGIAML_00836 5.5e-127 XK27_08875 O Zinc-dependent metalloprotease
AAPGIAML_00837 2.8e-18 XK27_08880
AAPGIAML_00838 1e-75 fld C Flavodoxin
AAPGIAML_00839 1.9e-281 clcA P Chloride transporter, ClC family
AAPGIAML_00840 1.2e-37 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
AAPGIAML_00841 4.5e-214 XK27_05110 P Chloride transporter ClC family
AAPGIAML_00842 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AAPGIAML_00845 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
AAPGIAML_00846 1.6e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AAPGIAML_00847 3.3e-86 ytsP 1.8.4.14 T GAF domain-containing protein
AAPGIAML_00848 5.4e-303 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AAPGIAML_00849 7.3e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AAPGIAML_00850 3.5e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AAPGIAML_00851 1.1e-274 5.1.3.2 GM Psort location CytoplasmicMembrane, score
AAPGIAML_00852 1.5e-145
AAPGIAML_00853 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
AAPGIAML_00854 1.9e-272 pelF GT4 M Domain of unknown function (DUF3492)
AAPGIAML_00855 5.4e-182 pelG M Putative exopolysaccharide Exporter (EPS-E)
AAPGIAML_00856 1.3e-222 cotH M CotH kinase protein
AAPGIAML_00857 3e-96 P VTC domain
AAPGIAML_00858 1.2e-83 S membrane
AAPGIAML_00859 6.4e-135 G Domain of unknown function (DUF4832)
AAPGIAML_00860 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AAPGIAML_00861 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAPGIAML_00862 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
AAPGIAML_00863 1.2e-152 endA F DNA RNA non-specific endonuclease
AAPGIAML_00864 2.9e-111 tcyB_2 P ABC transporter (permease)
AAPGIAML_00865 1.9e-116 gltJ P ABC transporter (Permease
AAPGIAML_00866 1.4e-142 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
AAPGIAML_00867 1.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
AAPGIAML_00868 1.4e-223 L the current gene model (or a revised gene model) may contain a frame shift
AAPGIAML_00869 6.5e-111 tcyB_2 P ABC transporter (permease)
AAPGIAML_00870 1.9e-116 gltJ P ABC transporter (Permease
AAPGIAML_00871 1.2e-146 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
AAPGIAML_00872 1.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
AAPGIAML_00873 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AAPGIAML_00874 3.2e-220 vicK 2.7.13.3 T Histidine kinase
AAPGIAML_00875 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
AAPGIAML_00876 1e-57 S Protein of unknown function (DUF454)
AAPGIAML_00877 1.3e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
AAPGIAML_00878 4.6e-146 yidA S hydrolases of the HAD superfamily
AAPGIAML_00879 1.2e-144 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
AAPGIAML_00880 1.5e-67 ywiB S Domain of unknown function (DUF1934)
AAPGIAML_00881 0.0 pacL 3.6.3.8 P cation transport ATPase
AAPGIAML_00882 1.3e-131 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
AAPGIAML_00883 1.4e-158 yjjH S Calcineurin-like phosphoesterase
AAPGIAML_00884 3.2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AAPGIAML_00885 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AAPGIAML_00886 3.2e-124 ftsE D cell division ATP-binding protein FtsE
AAPGIAML_00887 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
AAPGIAML_00888 3.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
AAPGIAML_00889 3.6e-176 yubA S permease
AAPGIAML_00890 1.5e-220 G COG0457 FOG TPR repeat
AAPGIAML_00891 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AAPGIAML_00892 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AAPGIAML_00893 2e-230 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AAPGIAML_00894 1.5e-86 ebsA S Family of unknown function (DUF5322)
AAPGIAML_00895 2.5e-17 M LysM domain
AAPGIAML_00896 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AAPGIAML_00897 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AAPGIAML_00898 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AAPGIAML_00899 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AAPGIAML_00900 5.5e-83 XK27_03610 K Gnat family
AAPGIAML_00901 2.1e-55 yybC
AAPGIAML_00902 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
AAPGIAML_00903 2.5e-272 pepV 3.5.1.18 E Dipeptidase
AAPGIAML_00904 1.6e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
AAPGIAML_00905 6.5e-227 V Glucan-binding protein C
AAPGIAML_00906 8e-252 V Glucan-binding protein C
AAPGIAML_00907 5.6e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AAPGIAML_00908 2.1e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
AAPGIAML_00909 1.4e-95 S Protein of unknown function (DUF1697)
AAPGIAML_00910 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AAPGIAML_00911 2.8e-171 clcA_2 P Chloride transporter, ClC family
AAPGIAML_00912 6.7e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
AAPGIAML_00913 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
AAPGIAML_00914 9.4e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
AAPGIAML_00915 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
AAPGIAML_00916 1.7e-109 cps4C M biosynthesis protein
AAPGIAML_00917 1.3e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
AAPGIAML_00918 1e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
AAPGIAML_00919 2.6e-219 rgpAc GT4 M group 1 family protein
AAPGIAML_00920 4.4e-211 wcoF M Glycosyltransferase, group 1 family protein
AAPGIAML_00921 3.4e-120 Z012_10770 M Domain of unknown function (DUF1919)
AAPGIAML_00922 4e-165
AAPGIAML_00923 2.9e-164 M Glycosyltransferase like family 2
AAPGIAML_00924 1.7e-122 cps3F
AAPGIAML_00925 2.4e-243 epsU S Polysaccharide biosynthesis protein
AAPGIAML_00926 1.1e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
AAPGIAML_00927 2.7e-185 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
AAPGIAML_00928 3.8e-177 wbbI M transferase activity, transferring glycosyl groups
AAPGIAML_00930 3.6e-151 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
AAPGIAML_00931 1.1e-107 pgm G Belongs to the phosphoglycerate mutase family
AAPGIAML_00932 1.1e-107 G Belongs to the phosphoglycerate mutase family
AAPGIAML_00933 5.3e-107 G Belongs to the phosphoglycerate mutase family
AAPGIAML_00934 6.8e-196 S hmm pf01594
AAPGIAML_00935 2.2e-284 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAPGIAML_00936 4.1e-38 S granule-associated protein
AAPGIAML_00937 5.4e-284 S unusual protein kinase
AAPGIAML_00938 1.1e-99 estA E Lysophospholipase L1 and related esterases
AAPGIAML_00939 1.4e-153 rssA S Phospholipase, patatin family
AAPGIAML_00940 4.5e-247 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
AAPGIAML_00941 8.1e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AAPGIAML_00942 1.2e-120 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AAPGIAML_00943 9.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AAPGIAML_00944 3.3e-166 S the current gene model (or a revised gene model) may contain a frame shift
AAPGIAML_00945 1.8e-224 2.7.13.3 T protein histidine kinase activity
AAPGIAML_00946 9.8e-204 hpk9 2.7.13.3 T protein histidine kinase activity
AAPGIAML_00947 1.5e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
AAPGIAML_00948 4.1e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AAPGIAML_00949 7.6e-210 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AAPGIAML_00950 0.0 lpdA 1.8.1.4 C Dehydrogenase
AAPGIAML_00951 0.0 3.5.1.28 NU amidase activity
AAPGIAML_00952 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
AAPGIAML_00953 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AAPGIAML_00954 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
AAPGIAML_00955 9e-231 ycdB P peroxidase
AAPGIAML_00956 1.7e-288 ywbL P COG0672 High-affinity Fe2 Pb2 permease
AAPGIAML_00957 5.4e-119 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AAPGIAML_00958 9.5e-23 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
AAPGIAML_00959 4.7e-213 msmX P Belongs to the ABC transporter superfamily
AAPGIAML_00960 2.2e-151 malG P ABC transporter (Permease
AAPGIAML_00961 8.2e-249 malF P ABC transporter (Permease
AAPGIAML_00962 3.9e-229 malX G ABC transporter
AAPGIAML_00963 2.1e-156 malR K Transcriptional regulator
AAPGIAML_00964 2.1e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
AAPGIAML_00965 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AAPGIAML_00966 6.8e-39
AAPGIAML_00967 3.6e-185 lplA 6.3.1.20 H Lipoate-protein ligase
AAPGIAML_00968 3.5e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
AAPGIAML_00969 0.0 pepN 3.4.11.2 E aminopeptidase
AAPGIAML_00970 7.1e-113 phoU P Plays a role in the regulation of phosphate uptake
AAPGIAML_00971 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AAPGIAML_00972 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AAPGIAML_00973 1.3e-154 pstA P phosphate transport system permease
AAPGIAML_00974 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
AAPGIAML_00975 9e-156 pstS P phosphate
AAPGIAML_00976 8.5e-251 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
AAPGIAML_00977 1.3e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
AAPGIAML_00978 1.5e-43 yktA S Belongs to the UPF0223 family
AAPGIAML_00979 7.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AAPGIAML_00980 4e-167 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AAPGIAML_00981 1.5e-153 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AAPGIAML_00982 3e-243 XK27_04775 S hemerythrin HHE cation binding domain
AAPGIAML_00983 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
AAPGIAML_00984 4.8e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
AAPGIAML_00985 3.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AAPGIAML_00986 4.7e-137 S haloacid dehalogenase-like hydrolase
AAPGIAML_00987 3.9e-240 metY 2.5.1.49 E o-acetylhomoserine
AAPGIAML_00988 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AAPGIAML_00989 3.7e-241 agcS E (Alanine) symporter
AAPGIAML_00990 1e-243 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AAPGIAML_00991 1.3e-176 bglC K Transcriptional regulator
AAPGIAML_00992 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
AAPGIAML_00993 6.4e-82 yecS P ABC transporter (Permease
AAPGIAML_00994 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
AAPGIAML_00995 4.7e-242 nylA 3.5.1.4 J Belongs to the amidase family
AAPGIAML_00996 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AAPGIAML_00997 2.2e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AAPGIAML_00998 1e-147 csm6 S Psort location Cytoplasmic, score
AAPGIAML_00999 3.9e-114 csm6 S Psort location Cytoplasmic, score
AAPGIAML_01000 4.1e-203 csm5 L CRISPR-associated RAMP protein, Csm5 family
AAPGIAML_01001 3.7e-165 csm4 L CRISPR-associated RAMP protein, Csm4 family
AAPGIAML_01002 2.4e-116 csm3 L RAMP superfamily
AAPGIAML_01003 7.3e-62 csm2 L Pfam:DUF310
AAPGIAML_01004 0.0 csm1 S CRISPR-associated protein Csm1 family
AAPGIAML_01005 1.6e-129 cas6 S Pfam:DUF2276
AAPGIAML_01007 5.4e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AAPGIAML_01008 4.5e-36 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AAPGIAML_01009 9.6e-81 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AAPGIAML_01010 1.3e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AAPGIAML_01011 1.6e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
AAPGIAML_01012 8e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
AAPGIAML_01013 2.2e-132 S TraX protein
AAPGIAML_01014 4.7e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
AAPGIAML_01015 2.3e-271 S Psort location CytoplasmicMembrane, score
AAPGIAML_01016 1.3e-87 V ABC transporter, ATP-binding protein
AAPGIAML_01017 9.3e-47
AAPGIAML_01018 6.9e-232 dinF V Mate efflux family protein
AAPGIAML_01019 8.4e-179 yclQ P ABC-type enterochelin transport system, periplasmic component
AAPGIAML_01020 0.0 V Type III restriction enzyme, res subunit
AAPGIAML_01021 3.3e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
AAPGIAML_01022 3e-131 2.4.2.3 F Phosphorylase superfamily
AAPGIAML_01023 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AAPGIAML_01024 0.0 copA 3.6.3.54 P P-type ATPase
AAPGIAML_01025 3.7e-66 silP 1.9.3.1, 3.6.3.54 S cog cog4633
AAPGIAML_01026 3.3e-65 copY K Copper transport repressor, CopY TcrY family
AAPGIAML_01027 3.3e-189 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
AAPGIAML_01028 3e-193 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
AAPGIAML_01029 1.7e-141 czcD P cation diffusion facilitator family transporter
AAPGIAML_01030 1.8e-90 K Transcriptional regulator, TetR family
AAPGIAML_01031 6e-56 S Protein of unknown function with HXXEE motif
AAPGIAML_01032 8.5e-108 K Bacterial regulatory proteins, tetR family
AAPGIAML_01033 5.8e-181 ybhR V ABC transporter
AAPGIAML_01034 1e-125 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
AAPGIAML_01035 5.5e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AAPGIAML_01036 2.3e-153 I Alpha/beta hydrolase family
AAPGIAML_01037 4e-176 1.1.1.1 C nadph quinone reductase
AAPGIAML_01038 1.5e-66 K Transcriptional regulator
AAPGIAML_01039 4.6e-61 pnuC H nicotinamide mononucleotide transporter
AAPGIAML_01040 1.4e-150 cbiO2 P ABC transporter, ATP-binding protein
AAPGIAML_01041 3.9e-156 P ATPase activity
AAPGIAML_01042 1.7e-132 cbiQ P cobalt transport
AAPGIAML_01043 3.7e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
AAPGIAML_01044 1.1e-71 S Phenazine biosynthesis protein
AAPGIAML_01045 1.6e-52 S Phenazine biosynthesis protein
AAPGIAML_01046 2e-92 tetR K transcriptional regulator
AAPGIAML_01047 4.3e-124 V abc transporter atp-binding protein
AAPGIAML_01048 0.0 V ABC transporter (Permease
AAPGIAML_01049 1.1e-110 magIII L Base excision DNA repair protein, HhH-GPD family
AAPGIAML_01050 4.4e-275 proWX P ABC transporter
AAPGIAML_01051 2.4e-130 proV E abc transporter atp-binding protein
AAPGIAML_01052 8.2e-146 1.6.5.2 GM epimerase
AAPGIAML_01053 8.1e-76 mgrA K Transcriptional regulator, MarR family
AAPGIAML_01054 9.2e-80 S Macro domain
AAPGIAML_01055 2.4e-94 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
AAPGIAML_01056 8.9e-40 C Pyridoxamine 5'-phosphate oxidase
AAPGIAML_01057 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
AAPGIAML_01058 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
AAPGIAML_01061 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AAPGIAML_01063 8.2e-137 IQ Acetoin reductase
AAPGIAML_01064 1.4e-41 pspE P Rhodanese-like protein
AAPGIAML_01065 4.2e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
AAPGIAML_01066 3.6e-221 XK27_05470 E Methionine synthase
AAPGIAML_01067 2.8e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AAPGIAML_01068 5.6e-229 T PhoQ Sensor
AAPGIAML_01069 3e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AAPGIAML_01071 9.1e-53 V ABC-2 family transporter protein
AAPGIAML_01072 1.3e-82 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
AAPGIAML_01073 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AAPGIAML_01074 7.8e-157 dprA LU DNA protecting protein DprA
AAPGIAML_01075 1e-165 GK ROK family
AAPGIAML_01076 2.6e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AAPGIAML_01077 7.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AAPGIAML_01078 6.2e-128 K DNA-binding helix-turn-helix protein
AAPGIAML_01079 1.7e-90 niaR S small molecule binding protein (contains 3H domain)
AAPGIAML_01080 2.7e-86
AAPGIAML_01081 1.7e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AAPGIAML_01082 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AAPGIAML_01083 7.7e-126 gntR1 K transcriptional
AAPGIAML_01084 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AAPGIAML_01085 3.6e-100 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AAPGIAML_01086 7.2e-189 adhP 1.1.1.1 C alcohol dehydrogenase
AAPGIAML_01087 2.1e-45
AAPGIAML_01088 2.3e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AAPGIAML_01089 4.6e-157 aatB ET ABC transporter substrate-binding protein
AAPGIAML_01090 1.7e-111 glnQ 3.6.3.21 E abc transporter atp-binding protein
AAPGIAML_01091 3.1e-105 artQ P ABC transporter (Permease
AAPGIAML_01092 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
AAPGIAML_01093 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AAPGIAML_01094 8.4e-165 cpsY K Transcriptional regulator
AAPGIAML_01095 7.9e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
AAPGIAML_01096 3.9e-163 yeiH S Membrane
AAPGIAML_01098 2.6e-09
AAPGIAML_01099 1.5e-291 adcA P Belongs to the bacterial solute-binding protein 9 family
AAPGIAML_01100 1.5e-144 XK27_10720 D peptidase activity
AAPGIAML_01101 1.3e-273 pepD E Dipeptidase
AAPGIAML_01102 1.3e-160 whiA K May be required for sporulation
AAPGIAML_01103 5.3e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AAPGIAML_01104 2e-163 rapZ S Displays ATPase and GTPase activities
AAPGIAML_01105 3.1e-136 yejC S cyclic nucleotide-binding protein
AAPGIAML_01106 1.1e-198 D nuclear chromosome segregation
AAPGIAML_01107 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
AAPGIAML_01108 2.7e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
AAPGIAML_01109 1.4e-80 queD 4.1.2.50, 4.2.3.12 H synthase
AAPGIAML_01110 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AAPGIAML_01111 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
AAPGIAML_01112 1.5e-201 pmrB EGP Major facilitator Superfamily
AAPGIAML_01113 2.8e-19
AAPGIAML_01114 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
AAPGIAML_01115 7e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AAPGIAML_01116 1.1e-81 ypmB S Protein conserved in bacteria
AAPGIAML_01117 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AAPGIAML_01118 8.3e-119 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
AAPGIAML_01119 2.3e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
AAPGIAML_01120 1.7e-180 yufP S Belongs to the binding-protein-dependent transport system permease family
AAPGIAML_01121 1.6e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
AAPGIAML_01122 3.2e-187 tcsA S membrane
AAPGIAML_01123 2.2e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
AAPGIAML_01124 1.8e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AAPGIAML_01125 5e-232 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
AAPGIAML_01126 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
AAPGIAML_01127 2.1e-171 coaA 2.7.1.33 F Pantothenic acid kinase
AAPGIAML_01128 1e-29 rpsT J Binds directly to 16S ribosomal RNA
AAPGIAML_01129 1.6e-231 T PhoQ Sensor
AAPGIAML_01130 4.7e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AAPGIAML_01131 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
AAPGIAML_01132 3.5e-115 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
AAPGIAML_01133 5.7e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AAPGIAML_01134 4.1e-93 panT S ECF transporter, substrate-specific component
AAPGIAML_01135 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
AAPGIAML_01136 1.6e-165 metF 1.5.1.20 E reductase
AAPGIAML_01137 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AAPGIAML_01139 1.4e-309 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
AAPGIAML_01140 0.0 3.6.3.8 P cation transport ATPase
AAPGIAML_01141 6.3e-243 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AAPGIAML_01142 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AAPGIAML_01143 6.9e-234 dltB M Membrane protein involved in D-alanine export
AAPGIAML_01144 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AAPGIAML_01145 3.2e-145 L Integrase core domain protein
AAPGIAML_01146 5.9e-123 L Helix-turn-helix domain
AAPGIAML_01147 3.7e-87 L COG1943 Transposase and inactivated derivatives
AAPGIAML_01148 0.0 XK27_10035 V abc transporter atp-binding protein
AAPGIAML_01149 1.1e-290 yfiB1 V abc transporter atp-binding protein
AAPGIAML_01150 1.2e-98 pvaA M lytic transglycosylase activity
AAPGIAML_01151 1.9e-178 ndpA S 37-kD nucleoid-associated bacterial protein
AAPGIAML_01152 1e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AAPGIAML_01153 4.4e-101 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AAPGIAML_01154 2.5e-131 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AAPGIAML_01155 1.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AAPGIAML_01156 5.1e-110 tdk 2.7.1.21 F thymidine kinase
AAPGIAML_01157 1.5e-186 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AAPGIAML_01158 1.2e-151 gst O Glutathione S-transferase
AAPGIAML_01159 1e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
AAPGIAML_01160 1e-173 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
AAPGIAML_01161 4.4e-45 rpmE2 J 50S ribosomal protein L31
AAPGIAML_01162 6.1e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
AAPGIAML_01163 7.6e-164 ypuA S secreted protein
AAPGIAML_01164 9.1e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
AAPGIAML_01165 1.7e-126 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
AAPGIAML_01166 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAPGIAML_01167 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AAPGIAML_01168 6.6e-254 noxE P NADH oxidase
AAPGIAML_01169 4.3e-294 yfmM S abc transporter atp-binding protein
AAPGIAML_01170 2.8e-83 XK27_01265 S ECF-type riboflavin transporter, S component
AAPGIAML_01171 2.6e-152 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
AAPGIAML_01172 2.2e-85 S ECF-type riboflavin transporter, S component
AAPGIAML_01174 7.9e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AAPGIAML_01175 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
AAPGIAML_01177 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AAPGIAML_01178 5.4e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AAPGIAML_01179 3.9e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AAPGIAML_01180 1.9e-17 WQ51_00220 K Helix-turn-helix domain
AAPGIAML_01181 2.4e-90 S Protein of unknown function (DUF3278)
AAPGIAML_01182 0.0 smc D Required for chromosome condensation and partitioning
AAPGIAML_01183 6e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AAPGIAML_01184 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AAPGIAML_01185 5.2e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AAPGIAML_01187 2.2e-290 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAPGIAML_01188 1.1e-89 pat 2.3.1.183 M acetyltransferase
AAPGIAML_01189 5.9e-258 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AAPGIAML_01190 3.4e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AAPGIAML_01191 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AAPGIAML_01192 3.7e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
AAPGIAML_01193 1.8e-119 sdaAB 4.3.1.17 E L-serine dehydratase
AAPGIAML_01194 3.4e-147 sdaAA 4.3.1.17 E L-serine dehydratase
AAPGIAML_01195 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
AAPGIAML_01196 4.7e-163 yjlA EG membrane
AAPGIAML_01197 1.6e-80 3.4.21.89 S RDD family
AAPGIAML_01198 7.7e-150 K sequence-specific DNA binding
AAPGIAML_01199 6e-149 V ABC transporter, ATP-binding protein
AAPGIAML_01200 6.8e-93 S ABC-2 family transporter protein
AAPGIAML_01201 8e-131 K sequence-specific DNA binding
AAPGIAML_01202 2.7e-51 ywrO S general stress protein
AAPGIAML_01203 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
AAPGIAML_01204 5.7e-77 K Acetyltransferase (GNAT) domain
AAPGIAML_01205 3.3e-141 S ABC-2 family transporter protein
AAPGIAML_01206 9e-142 S ABC-2 family transporter protein
AAPGIAML_01207 2.7e-185 S abc transporter atp-binding protein
AAPGIAML_01208 1.3e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AAPGIAML_01209 9.1e-190 desK 2.7.13.3 T Histidine kinase
AAPGIAML_01210 2e-132 yvfS V ABC-2 type transporter
AAPGIAML_01211 1e-159 XK27_09825 V abc transporter atp-binding protein
AAPGIAML_01214 1.8e-165 yocS S Transporter
AAPGIAML_01215 1.2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
AAPGIAML_01216 2.2e-115 yvfS V Transporter
AAPGIAML_01217 9e-156 XK27_09825 V abc transporter atp-binding protein
AAPGIAML_01218 4.1e-15 liaI KT membrane
AAPGIAML_01219 5.8e-30 liaI KT membrane
AAPGIAML_01220 6.1e-93 XK27_05000 S metal cluster binding
AAPGIAML_01221 0.0 V ABC transporter (permease)
AAPGIAML_01222 1.1e-133 macB2 V ABC transporter, ATP-binding protein
AAPGIAML_01223 9.7e-151 T Histidine kinase
AAPGIAML_01224 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AAPGIAML_01225 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AAPGIAML_01226 7.2e-223 pbuX F xanthine permease
AAPGIAML_01227 2.1e-141 L Transposase and inactivated derivatives
AAPGIAML_01228 5.3e-74 L Transposase
AAPGIAML_01229 2.8e-59 pdxH S pyridoxamine 5'-phosphate oxidase
AAPGIAML_01230 3e-243 norM V Multidrug efflux pump
AAPGIAML_01232 1.6e-111 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAPGIAML_01233 2.4e-54 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AAPGIAML_01234 1.7e-230 brnQ E Component of the transport system for branched-chain amino acids
AAPGIAML_01235 7.8e-182 manA 5.3.1.8 G mannose-6-phosphate isomerase
AAPGIAML_01236 2e-58 S Protein of unknown function (DUF3290)
AAPGIAML_01237 1.3e-100 S Protein of unknown function (DUF421)
AAPGIAML_01238 5.9e-15 csbD K CsbD-like
AAPGIAML_01239 4.9e-85 S Carbohydrate-binding domain-containing protein Cthe_2159
AAPGIAML_01240 4.3e-213 yfnA E amino acid
AAPGIAML_01241 0.0 S dextransucrase activity
AAPGIAML_01242 2.5e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
AAPGIAML_01243 1.5e-42 S Sugar efflux transporter for intercellular exchange
AAPGIAML_01244 2.6e-203 P FtsX-like permease family
AAPGIAML_01245 6e-123 V abc transporter atp-binding protein
AAPGIAML_01246 2.8e-97 K WHG domain
AAPGIAML_01247 8.8e-170 ydhF S Aldo keto reductase
AAPGIAML_01248 1.1e-06 S Protein of unknown function (DUF3169)
AAPGIAML_01249 2.5e-27 XK27_07105 K transcriptional
AAPGIAML_01250 2.7e-27
AAPGIAML_01251 1.3e-108 XK27_02070 S nitroreductase
AAPGIAML_01252 4.5e-152 1.13.11.2 S glyoxalase
AAPGIAML_01253 1.1e-77 ywnA K Transcriptional regulator
AAPGIAML_01254 2.2e-154 E Alpha/beta hydrolase of unknown function (DUF915)
AAPGIAML_01255 1.1e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AAPGIAML_01256 2.4e-167 bcrA V abc transporter atp-binding protein
AAPGIAML_01257 7.2e-87 S ABC-2 family transporter protein
AAPGIAML_01258 9.4e-45 S Domain of unknown function (DUF4352)
AAPGIAML_01259 7.7e-131 T PhoQ Sensor
AAPGIAML_01260 1.9e-121 T Xre family transcriptional regulator
AAPGIAML_01261 5.4e-110 drgA C nitroreductase
AAPGIAML_01262 8.2e-96 yoaK S Protein of unknown function (DUF1275)
AAPGIAML_01263 2.9e-224 L Transposase
AAPGIAML_01264 1.2e-157 yvgN C reductase
AAPGIAML_01265 1.4e-209 S Tetratricopeptide repeat
AAPGIAML_01266 0.0 lacL 3.2.1.23 G -beta-galactosidase
AAPGIAML_01267 0.0 lacS G transporter
AAPGIAML_01268 4.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
AAPGIAML_01269 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AAPGIAML_01270 2.6e-288 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
AAPGIAML_01271 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AAPGIAML_01272 1.7e-182 galR K Transcriptional regulator
AAPGIAML_01273 2.7e-307 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
AAPGIAML_01274 5.9e-123 L Helix-turn-helix domain
AAPGIAML_01275 3.2e-145 L Integrase core domain protein
AAPGIAML_01276 1.7e-222 vncS 2.7.13.3 T Histidine kinase
AAPGIAML_01277 6.3e-114 K Response regulator receiver domain protein
AAPGIAML_01278 1.1e-235 vex3 V Efflux ABC transporter, permease protein
AAPGIAML_01279 6.6e-108 vex2 V abc transporter atp-binding protein
AAPGIAML_01280 1.2e-180 vex1 V Efflux ABC transporter, permease protein
AAPGIAML_01281 3.3e-283 XK27_07020 S Belongs to the UPF0371 family
AAPGIAML_01283 2.2e-199 gldA 1.1.1.6 C glycerol dehydrogenase
AAPGIAML_01284 1.1e-178 XK27_10475 S oxidoreductase
AAPGIAML_01285 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
AAPGIAML_01286 1.2e-95 dhaL 2.7.1.121 S Dihydroxyacetone kinase
AAPGIAML_01287 1e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
AAPGIAML_01288 4.5e-225 thrE K Psort location CytoplasmicMembrane, score
AAPGIAML_01289 3.2e-134 T Ser Thr phosphatase family protein
AAPGIAML_01290 5.5e-34 S Immunity protein 41
AAPGIAML_01291 1.4e-14 S integral membrane protein
AAPGIAML_01292 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
AAPGIAML_01293 3.9e-107 yhfC S Putative membrane peptidase family (DUF2324)
AAPGIAML_01295 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AAPGIAML_01297 3.6e-245 S dextransucrase activity
AAPGIAML_01298 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AAPGIAML_01299 3.2e-145 L Integrase core domain protein
AAPGIAML_01300 5.9e-123 L Helix-turn-helix domain
AAPGIAML_01301 1.9e-88 L COG1943 Transposase and inactivated derivatives
AAPGIAML_01302 1.9e-85 S dextransucrase activity
AAPGIAML_01303 3.2e-235 S dextransucrase activity
AAPGIAML_01304 0.0 S dextransucrase activity
AAPGIAML_01305 0.0 S dextransucrase activity
AAPGIAML_01306 6.1e-96 M Putative cell wall binding repeat
AAPGIAML_01307 4.6e-271 S dextransucrase activity
AAPGIAML_01308 7.9e-85 S dextransucrase activity
AAPGIAML_01309 1.2e-100 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AAPGIAML_01310 2e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AAPGIAML_01311 0.0 M Putative cell wall binding repeat
AAPGIAML_01312 1.1e-299 S dextransucrase activity
AAPGIAML_01313 3.6e-175 S dextransucrase activity
AAPGIAML_01314 0.0 S dextransucrase activity
AAPGIAML_01315 0.0 M Putative cell wall binding repeat
AAPGIAML_01316 3.1e-225 S dextransucrase activity
AAPGIAML_01318 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AAPGIAML_01319 2.8e-163 mleP S auxin efflux carrier
AAPGIAML_01320 2.2e-309 sfcA 1.1.1.38, 4.1.1.101 C malic enzyme
AAPGIAML_01321 2.1e-47 K Helix-turn-helix
AAPGIAML_01322 1.8e-119 mleR K malolactic fermentation system
AAPGIAML_01323 3.2e-145 L Integrase core domain protein
AAPGIAML_01324 5.9e-123 L Helix-turn-helix domain
AAPGIAML_01325 3.7e-87 L COG1943 Transposase and inactivated derivatives
AAPGIAML_01326 1.6e-132 XK27_00785 S CAAX protease self-immunity
AAPGIAML_01327 1.3e-238 EGP Major facilitator Superfamily
AAPGIAML_01328 3.1e-66 rmaI K Transcriptional regulator, MarR family
AAPGIAML_01329 4e-88 maa 2.3.1.79 GK Maltose O-acetyltransferase
AAPGIAML_01330 6.3e-134 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
AAPGIAML_01331 0.0 3.5.1.28 M domain protein
AAPGIAML_01332 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
AAPGIAML_01333 1.9e-21
AAPGIAML_01334 0.0 sraP UW domain, Protein
AAPGIAML_01335 1.5e-78 sraP UW Hep Hag repeat protein
AAPGIAML_01336 3.2e-101 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
AAPGIAML_01337 2.2e-75 fliF 2.1.1.72 N bacterial-type flagellum-dependent cell motility
AAPGIAML_01338 4.4e-263 sraP UW this gene contains a nucleotide ambiguity which may be the result of a sequencing error
AAPGIAML_01339 5.4e-189 nss M transferase activity, transferring glycosyl groups
AAPGIAML_01340 4.7e-16 S Accessory secretory protein Sec, Asp5
AAPGIAML_01341 2.6e-17 S Accessory secretory protein Sec Asp4
AAPGIAML_01342 9e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
AAPGIAML_01343 1.1e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AAPGIAML_01344 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AAPGIAML_01345 1.1e-77 asp3 S Accessory Sec system protein Asp3
AAPGIAML_01346 3.2e-289 asp2 3.4.11.5 S Accessory Sec system protein Asp2
AAPGIAML_01347 1.8e-287 asp1 S Accessory Sec system protein Asp1
AAPGIAML_01348 1.9e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
AAPGIAML_01349 0.0 M family 8
AAPGIAML_01350 0.0 sbcC L ATPase involved in DNA repair
AAPGIAML_01351 2.3e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AAPGIAML_01352 0.0 GM domain, Protein
AAPGIAML_01353 0.0 zmpB M signal peptide protein, YSIRK family
AAPGIAML_01354 0.0 M domain protein
AAPGIAML_01355 2e-11
AAPGIAML_01356 2.2e-186 XK27_10075 S abc transporter atp-binding protein
AAPGIAML_01357 0.0 V abc transporter atp-binding protein
AAPGIAML_01358 6.8e-296 V abc transporter atp-binding protein
AAPGIAML_01359 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
AAPGIAML_01361 2.4e-281 S Protein of unknown function (DUF3114)
AAPGIAML_01362 1.2e-97 2.3.1.128 K Acetyltransferase GNAT Family
AAPGIAML_01363 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
AAPGIAML_01364 1.1e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
AAPGIAML_01365 6.4e-178 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
AAPGIAML_01366 3.5e-184 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AAPGIAML_01367 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AAPGIAML_01368 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
AAPGIAML_01369 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
AAPGIAML_01370 6.6e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
AAPGIAML_01371 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AAPGIAML_01372 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AAPGIAML_01375 1.4e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AAPGIAML_01376 1.9e-170 vraS 2.7.13.3 T Histidine kinase
AAPGIAML_01377 1.7e-117 yvqF S Membrane
AAPGIAML_01378 6.9e-104 kcsA P Ion transport protein
AAPGIAML_01379 4.9e-292 prkC 2.7.11.1 KLT serine threonine protein kinase
AAPGIAML_01380 1e-134 stp 3.1.3.16 T phosphatase
AAPGIAML_01381 6.6e-243 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AAPGIAML_01382 5.2e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AAPGIAML_01383 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AAPGIAML_01384 3.6e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
AAPGIAML_01385 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AAPGIAML_01386 1.8e-198 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AAPGIAML_01387 8.2e-143 XK27_02985 S overlaps another CDS with the same product name
AAPGIAML_01388 5e-145 supH S overlaps another CDS with the same product name
AAPGIAML_01389 2.1e-61 yvoA_1 K Transcriptional
AAPGIAML_01390 1.2e-118 skfE V abc transporter atp-binding protein
AAPGIAML_01391 9.9e-130 V Psort location CytoplasmicMembrane, score
AAPGIAML_01392 1e-170 oppF P Belongs to the ABC transporter superfamily
AAPGIAML_01393 4.6e-202 oppD P Belongs to the ABC transporter superfamily
AAPGIAML_01394 5.9e-166 amiD P ABC transporter (Permease
AAPGIAML_01395 1.1e-275 amiC P ABC transporter (Permease
AAPGIAML_01396 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
AAPGIAML_01397 0.0 amiA E ABC transporter, substrate-binding protein, family 5
AAPGIAML_01398 1e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
AAPGIAML_01399 7.7e-171 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
AAPGIAML_01400 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AAPGIAML_01401 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
AAPGIAML_01402 2.4e-101 yjbK S Adenylate cyclase
AAPGIAML_01403 9.6e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AAPGIAML_01404 1.5e-203 iscS 2.8.1.7 E Cysteine desulfurase
AAPGIAML_01405 8.2e-60 XK27_04120 S Putative amino acid metabolism
AAPGIAML_01406 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AAPGIAML_01407 1.3e-128 puuD T peptidase C26
AAPGIAML_01408 1.5e-118 radC E Belongs to the UPF0758 family
AAPGIAML_01409 0.0 rgpF M Rhamnan synthesis protein F
AAPGIAML_01410 9.2e-184 rgpEc GT2 M Glycosyl transferase family 2
AAPGIAML_01411 1.8e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AAPGIAML_01412 3.1e-142 rgpC GM Transport permease protein
AAPGIAML_01413 4e-173 rgpB GT2 M Glycosyltransferase, group 2 family protein
AAPGIAML_01414 9.5e-214 rgpA GT4 M Domain of unknown function (DUF1972)
AAPGIAML_01415 1.2e-139 S Predicted membrane protein (DUF2142)
AAPGIAML_01416 1.1e-128 2.7.8.12 M transferase activity, transferring glycosyl groups
AAPGIAML_01417 9.5e-215 amrA S polysaccharide biosynthetic process
AAPGIAML_01418 1.1e-45 XK27_09090 S Uncharacterized conserved protein (DUF2304)
AAPGIAML_01419 4.2e-124 ycbB S Glycosyl transferase family 2
AAPGIAML_01420 1.7e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AAPGIAML_01421 8.9e-240
AAPGIAML_01422 3e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
AAPGIAML_01423 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
AAPGIAML_01424 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AAPGIAML_01425 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AAPGIAML_01426 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AAPGIAML_01427 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AAPGIAML_01428 7.9e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
AAPGIAML_01429 5.6e-211 arcT 2.6.1.1 E Aminotransferase
AAPGIAML_01430 2.9e-137 ET Belongs to the bacterial solute-binding protein 3 family
AAPGIAML_01431 4.8e-135 ET ABC transporter
AAPGIAML_01432 1.8e-83 mutT 3.6.1.55 F Nudix family
AAPGIAML_01433 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AAPGIAML_01435 1.5e-164 S CAAX amino terminal protease family protein
AAPGIAML_01436 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
AAPGIAML_01437 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
AAPGIAML_01438 1.7e-17 XK27_00735
AAPGIAML_01439 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AAPGIAML_01441 1.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AAPGIAML_01442 5.7e-10 O ADP-ribosylglycohydrolase
AAPGIAML_01443 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
AAPGIAML_01444 6e-61 ycaO O OsmC-like protein
AAPGIAML_01446 3.6e-152 EG Permeases of the drug metabolite transporter (DMT) superfamily
AAPGIAML_01447 1.5e-07 N PFAM Uncharacterised protein family UPF0150
AAPGIAML_01448 4.1e-113 serB 3.1.3.3 E phosphoserine phosphatase
AAPGIAML_01449 6.4e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AAPGIAML_01450 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AAPGIAML_01451 3.2e-98 3.1.3.18 S IA, variant 1
AAPGIAML_01452 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
AAPGIAML_01453 3.5e-56 lrgA S Effector of murein hydrolase LrgA
AAPGIAML_01455 2.7e-58 arsC 1.20.4.1 P Belongs to the ArsC family
AAPGIAML_01456 8.3e-74 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
AAPGIAML_01457 7.7e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AAPGIAML_01458 1.9e-103 wecD M Acetyltransferase (GNAT) domain
AAPGIAML_01459 1.1e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AAPGIAML_01460 2e-158 GK ROK family
AAPGIAML_01461 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
AAPGIAML_01462 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
AAPGIAML_01463 2.6e-205 potD P spermidine putrescine ABC transporter
AAPGIAML_01464 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
AAPGIAML_01465 1.8e-139 potB P ABC-type spermidine putrescine transport system, permease component I
AAPGIAML_01466 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
AAPGIAML_01467 3.1e-167 murB 1.3.1.98 M cell wall formation
AAPGIAML_01468 8.2e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AAPGIAML_01469 1.3e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AAPGIAML_01470 1.7e-292 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
AAPGIAML_01471 4.5e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AAPGIAML_01472 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
AAPGIAML_01473 0.0 ydaO E amino acid
AAPGIAML_01474 7.4e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AAPGIAML_01475 1.5e-36 ylqC L Belongs to the UPF0109 family
AAPGIAML_01476 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AAPGIAML_01478 1.7e-211 2.7.13.3 T protein histidine kinase activity
AAPGIAML_01479 4.2e-122 agrA KT phosphorelay signal transduction system
AAPGIAML_01480 2.5e-167 O protein import
AAPGIAML_01481 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
AAPGIAML_01482 1.3e-17 yjdB S Domain of unknown function (DUF4767)
AAPGIAML_01483 2.7e-199 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AAPGIAML_01485 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
AAPGIAML_01486 2.2e-71 S QueT transporter
AAPGIAML_01488 1.2e-169 yfjR K regulation of single-species biofilm formation
AAPGIAML_01490 4.8e-185 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AAPGIAML_01491 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AAPGIAML_01492 1.8e-84 ccl S cog cog4708
AAPGIAML_01493 4.3e-156 rbn E Belongs to the UPF0761 family
AAPGIAML_01494 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
AAPGIAML_01495 3e-232 ytoI K transcriptional regulator containing CBS domains
AAPGIAML_01496 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
AAPGIAML_01497 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AAPGIAML_01498 0.0 comEC S Competence protein ComEC
AAPGIAML_01499 3.7e-88 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
AAPGIAML_01500 1.7e-142 plsC 2.3.1.51 I Acyltransferase
AAPGIAML_01501 4.5e-137 nodB3 G deacetylase
AAPGIAML_01502 3.3e-138 yabB 2.1.1.223 L Methyltransferase
AAPGIAML_01503 7.3e-40 yazA L endonuclease containing a URI domain
AAPGIAML_01504 1.7e-258 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AAPGIAML_01505 8.7e-154 corA P CorA-like protein
AAPGIAML_01506 3.3e-62 yjqA S Bacterial PH domain
AAPGIAML_01507 1.7e-99 thiT S Thiamine transporter
AAPGIAML_01508 1.4e-153 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
AAPGIAML_01509 4.4e-190 yjbB G Permeases of the major facilitator superfamily
AAPGIAML_01510 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AAPGIAML_01511 2.1e-117 ywaF S Integral membrane protein (intg_mem_TP0381)
AAPGIAML_01512 2.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AAPGIAML_01516 3.3e-155 cjaA ET ABC transporter substrate-binding protein
AAPGIAML_01517 2e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
AAPGIAML_01518 3e-106 P ABC transporter (Permease
AAPGIAML_01519 3.9e-114 papP P ABC transporter (Permease
AAPGIAML_01520 9.3e-192 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AAPGIAML_01521 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
AAPGIAML_01522 0.0 copA 3.6.3.54 P P-type ATPase
AAPGIAML_01523 5.2e-72 copY K negative regulation of transcription, DNA-templated
AAPGIAML_01524 4.7e-176 EGP Major facilitator Superfamily
AAPGIAML_01525 2.3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AAPGIAML_01526 3.4e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AAPGIAML_01527 3.9e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
AAPGIAML_01528 1.8e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
AAPGIAML_01529 3.9e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AAPGIAML_01530 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
AAPGIAML_01531 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AAPGIAML_01532 2e-58
AAPGIAML_01533 0.0 ctpE P E1-E2 ATPase
AAPGIAML_01534 4.9e-45
AAPGIAML_01535 9e-47
AAPGIAML_01536 3.9e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AAPGIAML_01538 1.9e-124 V abc transporter atp-binding protein
AAPGIAML_01539 0.0 V ABC transporter (Permease
AAPGIAML_01540 3.7e-123 K transcriptional regulator, MerR family
AAPGIAML_01541 7e-104 dnaQ 2.7.7.7 L DNA polymerase III
AAPGIAML_01542 2.6e-41 WQ51_02910 S Protein of unknown function, DUF536
AAPGIAML_01543 6.8e-65 XK27_02560 S cog cog2151
AAPGIAML_01544 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AAPGIAML_01545 6.3e-221 ytfP S Flavoprotein
AAPGIAML_01547 8.4e-119 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AAPGIAML_01548 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
AAPGIAML_01549 4.9e-177 ecsB U Bacterial ABC transporter protein EcsB
AAPGIAML_01550 3.4e-132 ecsA V abc transporter atp-binding protein
AAPGIAML_01551 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
AAPGIAML_01552 4.1e-07
AAPGIAML_01553 5.3e-43
AAPGIAML_01554 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
AAPGIAML_01555 1e-43 yoeB S Addiction module toxin, Txe YoeB family
AAPGIAML_01556 2.2e-38 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
AAPGIAML_01557 1.1e-195 ylbM S Belongs to the UPF0348 family
AAPGIAML_01558 3.2e-138 yqeM Q Methyltransferase domain protein
AAPGIAML_01559 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AAPGIAML_01560 7.8e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
AAPGIAML_01561 1e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AAPGIAML_01562 7.7e-49 yhbY J RNA-binding protein
AAPGIAML_01563 7.8e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
AAPGIAML_01564 1.4e-98 yqeG S hydrolase of the HAD superfamily
AAPGIAML_01565 1.5e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AAPGIAML_01566 5.6e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
AAPGIAML_01567 3.7e-61
AAPGIAML_01569 1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAPGIAML_01570 8.5e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AAPGIAML_01571 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AAPGIAML_01572 1.2e-234 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
AAPGIAML_01573 1.7e-190 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
AAPGIAML_01574 9.7e-158 H COG0463 Glycosyltransferases involved in cell wall biogenesis
AAPGIAML_01575 2.3e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
AAPGIAML_01576 3.4e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AAPGIAML_01577 6.4e-99 pncA Q isochorismatase
AAPGIAML_01578 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AAPGIAML_01579 7.6e-238 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
AAPGIAML_01580 9e-75 XK27_03180 T universal stress protein
AAPGIAML_01582 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AAPGIAML_01583 2.5e-10 MU outer membrane autotransporter barrel domain protein
AAPGIAML_01584 2.2e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
AAPGIAML_01585 5.6e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
AAPGIAML_01586 6.9e-218 L the current gene model (or a revised gene model) may contain a frame shift
AAPGIAML_01587 0.0 yjcE P NhaP-type Na H and K H antiporters
AAPGIAML_01589 1.2e-94 ytqB 2.1.1.176 J (SAM)-dependent
AAPGIAML_01590 3.2e-181 yhcC S radical SAM protein
AAPGIAML_01591 1.9e-187 ylbL T Belongs to the peptidase S16 family
AAPGIAML_01592 5e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AAPGIAML_01593 2.1e-91 rsmD 2.1.1.171 L Methyltransferase
AAPGIAML_01594 4.7e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AAPGIAML_01595 5e-10 S Protein of unknown function (DUF4059)
AAPGIAML_01596 6.1e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
AAPGIAML_01597 4.5e-158 yxeN P ABC transporter (Permease
AAPGIAML_01598 2.6e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
AAPGIAML_01599 8e-35
AAPGIAML_01600 2.8e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AAPGIAML_01601 0.0 pflB 2.3.1.54 C formate acetyltransferase'
AAPGIAML_01602 4.3e-141 cah 4.2.1.1 P carbonic anhydrase
AAPGIAML_01603 2e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AAPGIAML_01605 8.2e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
AAPGIAML_01606 2.3e-139 cppA E CppA N-terminal
AAPGIAML_01607 1e-106 V CAAX protease self-immunity
AAPGIAML_01608 5.7e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
AAPGIAML_01609 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
AAPGIAML_01610 3.1e-44 spiA K sequence-specific DNA binding
AAPGIAML_01614 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
AAPGIAML_01615 0.0 mdlB V abc transporter atp-binding protein
AAPGIAML_01616 0.0 mdlA V abc transporter atp-binding protein
AAPGIAML_01618 2e-86 XK27_09885 V Glycopeptide antibiotics resistance protein
AAPGIAML_01619 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AAPGIAML_01620 1.8e-61 yutD J protein conserved in bacteria
AAPGIAML_01621 2.4e-256 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
AAPGIAML_01623 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AAPGIAML_01624 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AAPGIAML_01625 0.0 ftsI 3.4.16.4 M penicillin-binding protein
AAPGIAML_01626 2.4e-45 ftsL D cell division protein FtsL
AAPGIAML_01627 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AAPGIAML_01628 4.2e-96
AAPGIAML_01630 1.3e-48 yhaI J Protein of unknown function (DUF805)
AAPGIAML_01631 3.8e-61 yhaI J Protein of unknown function (DUF805)
AAPGIAML_01632 1e-58 yhaI J Membrane
AAPGIAML_01633 2.7e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AAPGIAML_01634 7.5e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AAPGIAML_01635 1.4e-276 XK27_00765
AAPGIAML_01636 3.1e-133 ecsA_2 V abc transporter atp-binding protein
AAPGIAML_01637 4.7e-126 S Protein of unknown function (DUF554)
AAPGIAML_01638 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AAPGIAML_01639 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
AAPGIAML_01640 1.5e-245 2.7.13.3 T protein histidine kinase activity
AAPGIAML_01641 2.3e-232 dcuS 2.7.13.3 T protein histidine kinase activity
AAPGIAML_01642 6.8e-14
AAPGIAML_01645 5.8e-146 V Psort location CytoplasmicMembrane, score
AAPGIAML_01647 1.7e-298 O MreB/Mbl protein
AAPGIAML_01648 6.3e-120 liaI S membrane
AAPGIAML_01649 2e-74 XK27_02470 K LytTr DNA-binding domain protein
AAPGIAML_01650 0.0 KT response to antibiotic
AAPGIAML_01651 4.8e-104 yebC M Membrane
AAPGIAML_01652 1.4e-259 XK27_03190 S hydrolases of the HAD superfamily
AAPGIAML_01653 5.4e-178 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
AAPGIAML_01655 3.2e-30 yozG K Transcriptional regulator
AAPGIAML_01659 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AAPGIAML_01660 2.5e-203 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AAPGIAML_01661 3.4e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AAPGIAML_01662 1e-195 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AAPGIAML_01663 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AAPGIAML_01664 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AAPGIAML_01666 9e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
AAPGIAML_01667 3.5e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
AAPGIAML_01668 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AAPGIAML_01669 5.1e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
AAPGIAML_01670 3.4e-180 scrR K purine nucleotide biosynthetic process
AAPGIAML_01671 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AAPGIAML_01672 3.7e-61 yqhY S protein conserved in bacteria
AAPGIAML_01673 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AAPGIAML_01674 1.8e-83 comEB 3.5.4.12 F ComE operon protein 2
AAPGIAML_01675 5.4e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
AAPGIAML_01677 2.3e-145 V 'abc transporter, ATP-binding protein
AAPGIAML_01678 1.4e-31 blpT
AAPGIAML_01682 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AAPGIAML_01683 6.5e-168 corA P COG0598 Mg2 and Co2 transporters
AAPGIAML_01684 1e-122 XK27_01040 S Protein of unknown function (DUF1129)
AAPGIAML_01686 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AAPGIAML_01687 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AAPGIAML_01688 3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
AAPGIAML_01689 3.2e-42 XK27_05745
AAPGIAML_01690 2.5e-214 mutY L A G-specific adenine glycosylase
AAPGIAML_01693 5.2e-36
AAPGIAML_01695 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AAPGIAML_01696 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AAPGIAML_01697 5.3e-90 cvpA S toxin biosynthetic process
AAPGIAML_01698 1.4e-26 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AAPGIAML_01699 2.2e-154 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AAPGIAML_01700 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
AAPGIAML_01701 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AAPGIAML_01702 1.3e-46 azlD S branched-chain amino acid
AAPGIAML_01703 9.7e-113 azlC E AzlC protein
AAPGIAML_01704 6.2e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AAPGIAML_01705 1.7e-70 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
AAPGIAML_01706 2.7e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
AAPGIAML_01707 1.5e-33 ykzG S Belongs to the UPF0356 family
AAPGIAML_01708 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AAPGIAML_01709 3.6e-114 pscB M CHAP domain protein
AAPGIAML_01710 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
AAPGIAML_01711 2.5e-62 glnR K Transcriptional regulator
AAPGIAML_01712 3e-87 S Fusaric acid resistance protein-like
AAPGIAML_01713 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AAPGIAML_01714 1.3e-117
AAPGIAML_01715 1.3e-185 gap 1.2.1.12 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AAPGIAML_01716 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AAPGIAML_01717 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AAPGIAML_01718 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AAPGIAML_01719 4e-142 purR 2.4.2.7 F operon repressor
AAPGIAML_01720 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
AAPGIAML_01721 3.2e-170 rmuC S RmuC domain protein
AAPGIAML_01722 3.8e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
AAPGIAML_01723 3.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AAPGIAML_01724 9.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AAPGIAML_01726 2.6e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AAPGIAML_01727 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AAPGIAML_01728 1.6e-143 tatD L Hydrolase, tatd
AAPGIAML_01729 1.2e-73 yccU S CoA-binding protein
AAPGIAML_01730 2.4e-50 trxA O Belongs to the thioredoxin family
AAPGIAML_01731 1.7e-142 S Macro domain protein
AAPGIAML_01732 1.8e-61 L thioesterase
AAPGIAML_01733 1.6e-52 bta 1.8.1.8 CO cell redox homeostasis
AAPGIAML_01746 1.8e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AAPGIAML_01747 3.4e-14 rpmH J Ribosomal protein L34
AAPGIAML_01748 6.3e-102 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
AAPGIAML_01749 1.7e-105 K Transcriptional regulator
AAPGIAML_01750 1.2e-151 jag S RNA-binding protein
AAPGIAML_01751 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AAPGIAML_01752 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AAPGIAML_01753 3.3e-269 argH 4.3.2.1 E Argininosuccinate lyase
AAPGIAML_01754 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AAPGIAML_01755 7.2e-130 fasA KT Response regulator of the LytR AlgR family
AAPGIAML_01756 2.3e-224 fasC 2.7.13.3 T protein histidine kinase activity
AAPGIAML_01757 2.4e-210 hpk9 2.7.13.3 T protein histidine kinase activity
AAPGIAML_01758 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
AAPGIAML_01759 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
AAPGIAML_01760 6.7e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AAPGIAML_01761 0.0 amiA E ABC transporter, substrate-binding protein, family 5
AAPGIAML_01762 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AAPGIAML_01763 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AAPGIAML_01764 1.2e-50 S Protein of unknown function (DUF3397)
AAPGIAML_01765 3.5e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
AAPGIAML_01766 7e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
AAPGIAML_01767 4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AAPGIAML_01768 9.3e-76 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
AAPGIAML_01769 5e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
AAPGIAML_01770 3.1e-107 XK27_09620 S FMN reductase (NADPH) activity
AAPGIAML_01771 2.1e-230 XK27_09615 C reductase
AAPGIAML_01772 2.4e-139 fnt P Formate nitrite transporter
AAPGIAML_01773 1.8e-96 XK27_08585 S Psort location CytoplasmicMembrane, score
AAPGIAML_01774 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AAPGIAML_01775 1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AAPGIAML_01776 5.7e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
AAPGIAML_01777 2.2e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AAPGIAML_01778 6.3e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AAPGIAML_01779 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AAPGIAML_01780 1.2e-119 S HAD hydrolase, family IA, variant
AAPGIAML_01781 7.7e-157 rrmA 2.1.1.187 Q methyltransferase
AAPGIAML_01785 1.9e-89 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AAPGIAML_01786 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AAPGIAML_01787 8.3e-37 yeeD O sulfur carrier activity
AAPGIAML_01788 2e-186 yeeE S Sulphur transport
AAPGIAML_01789 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AAPGIAML_01790 2.6e-09 S NTF2 fold immunity protein
AAPGIAML_01791 1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AAPGIAML_01792 2e-08 XK27_10305 S Domain of unknown function (DUF4651)
AAPGIAML_01793 1.6e-202 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
AAPGIAML_01794 4.4e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AAPGIAML_01795 3.7e-101 S CAAX amino terminal protease family protein
AAPGIAML_01797 8.1e-109 V CAAX protease self-immunity
AAPGIAML_01798 8.8e-27 lanR K sequence-specific DNA binding
AAPGIAML_01799 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AAPGIAML_01800 5e-176 ytxK 2.1.1.72 L DNA methylase
AAPGIAML_01801 2e-12 comGF U Putative Competence protein ComGF
AAPGIAML_01802 5.4e-69 comGF U Competence protein ComGF
AAPGIAML_01803 5.3e-15 NU Type II secretory pathway pseudopilin
AAPGIAML_01804 1.4e-69 cglD NU Competence protein
AAPGIAML_01805 2.2e-43 comGC U Required for transformation and DNA binding
AAPGIAML_01806 6.3e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AAPGIAML_01807 4.2e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AAPGIAML_01808 2.5e-67 S cog cog4699
AAPGIAML_01809 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAPGIAML_01810 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAPGIAML_01811 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AAPGIAML_01812 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AAPGIAML_01813 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AAPGIAML_01814 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
AAPGIAML_01815 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
AAPGIAML_01816 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AAPGIAML_01817 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
AAPGIAML_01818 1.4e-57 asp S cog cog1302
AAPGIAML_01819 7.1e-226 norN V Mate efflux family protein
AAPGIAML_01820 1.3e-276 thrC 4.2.3.1 E Threonine synthase
AAPGIAML_01823 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
AAPGIAML_01824 0.0 pepO 3.4.24.71 O Peptidase family M13
AAPGIAML_01825 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AAPGIAML_01826 9.5e-291 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AAPGIAML_01827 7.9e-126 treR K trehalose operon
AAPGIAML_01828 1.9e-95 ywlG S Belongs to the UPF0340 family
AAPGIAML_01830 1.3e-92
AAPGIAML_01831 1.5e-70
AAPGIAML_01832 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
AAPGIAML_01834 7.4e-239 6.3.2.2 H gamma-glutamylcysteine synthetase
AAPGIAML_01835 4.4e-62 rplQ J ribosomal protein l17
AAPGIAML_01836 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AAPGIAML_01837 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AAPGIAML_01838 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AAPGIAML_01839 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AAPGIAML_01840 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AAPGIAML_01841 2.1e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AAPGIAML_01842 6.2e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AAPGIAML_01843 1.7e-57 rplO J binds to the 23S rRNA
AAPGIAML_01844 1.9e-23 rpmD J ribosomal protein l30
AAPGIAML_01845 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AAPGIAML_01846 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AAPGIAML_01847 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AAPGIAML_01848 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AAPGIAML_01849 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AAPGIAML_01850 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AAPGIAML_01851 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AAPGIAML_01852 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AAPGIAML_01853 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AAPGIAML_01854 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
AAPGIAML_01855 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AAPGIAML_01856 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AAPGIAML_01857 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AAPGIAML_01858 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AAPGIAML_01859 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AAPGIAML_01860 9.2e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AAPGIAML_01861 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
AAPGIAML_01862 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AAPGIAML_01863 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
AAPGIAML_01864 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AAPGIAML_01865 0.0 XK27_09800 I Acyltransferase
AAPGIAML_01866 2.8e-35 XK27_09805 S MORN repeat protein
AAPGIAML_01867 2.2e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AAPGIAML_01868 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AAPGIAML_01869 1.7e-90 adk 2.7.4.3 F topology modulation protein
AAPGIAML_01871 3.1e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
AAPGIAML_01872 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AAPGIAML_01873 6.3e-44 yrzL S Belongs to the UPF0297 family
AAPGIAML_01874 2.3e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AAPGIAML_01875 3.2e-44 yrzB S Belongs to the UPF0473 family
AAPGIAML_01876 1.3e-296 ccs S the current gene model (or a revised gene model) may contain a frame shift
AAPGIAML_01877 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
AAPGIAML_01878 2.2e-13
AAPGIAML_01879 1.2e-88 XK27_10930 K acetyltransferase
AAPGIAML_01880 7.7e-114 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AAPGIAML_01881 3.4e-121 yaaA S Belongs to the UPF0246 family
AAPGIAML_01882 9.3e-167 XK27_01785 S cog cog1284
AAPGIAML_01883 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
AAPGIAML_01885 1.9e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
AAPGIAML_01886 4.1e-75 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AAPGIAML_01887 4.4e-130 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
AAPGIAML_01888 3.6e-218 metE 2.1.1.14 E Methionine synthase
AAPGIAML_01889 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AAPGIAML_01890 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AAPGIAML_01891 7e-139 KLT Protein tyrosine kinase
AAPGIAML_01892 1.7e-57 KLT Protein tyrosine kinase
AAPGIAML_01893 3.4e-94 tnp* L An automated process has identified a potential problem with this gene model
AAPGIAML_01894 4.9e-131 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
AAPGIAML_01895 8.4e-60 fruR K transcriptional
AAPGIAML_01896 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
AAPGIAML_01897 5.4e-162 T Diguanylate cyclase
AAPGIAML_01898 1.2e-129 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
AAPGIAML_01899 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
AAPGIAML_01900 0.0
AAPGIAML_01905 7e-115 nudL L hydrolase
AAPGIAML_01906 6.3e-54 K transcriptional regulator, PadR family
AAPGIAML_01907 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
AAPGIAML_01908 4.4e-107 S Putative adhesin
AAPGIAML_01909 7.3e-160 XK27_06930 V domain protein
AAPGIAML_01910 2.4e-95 XK27_06935 K transcriptional regulator
AAPGIAML_01911 2e-53 ypaA M Membrane
AAPGIAML_01912 1.9e-10
AAPGIAML_01913 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AAPGIAML_01914 1.8e-47 veg S Biofilm formation stimulator VEG
AAPGIAML_01915 6.5e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AAPGIAML_01916 2.2e-73 rplI J binds to the 23S rRNA
AAPGIAML_01917 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AAPGIAML_01918 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AAPGIAML_01919 2.1e-98 yvbG U UPF0056 membrane protein
AAPGIAML_01920 2.1e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AAPGIAML_01921 7.1e-311 S Bacterial membrane protein, YfhO
AAPGIAML_01922 1.2e-65 isaA GH23 M Immunodominant staphylococcal antigen A
AAPGIAML_01923 1.2e-60 lytE M LysM domain protein
AAPGIAML_01924 4.1e-131 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AAPGIAML_01925 8.9e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AAPGIAML_01926 5.9e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AAPGIAML_01927 1.2e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AAPGIAML_01928 1.4e-129 S sequence-specific DNA binding
AAPGIAML_01929 1.5e-231 ymfH S Peptidase M16
AAPGIAML_01930 6.7e-229 ymfF S Peptidase M16
AAPGIAML_01931 4.9e-58 yaaA S S4 domain protein YaaA
AAPGIAML_01932 3e-201 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AAPGIAML_01933 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
AAPGIAML_01934 1.5e-225 L Transposase
AAPGIAML_01935 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
AAPGIAML_01936 7.8e-152 yvjA S membrane
AAPGIAML_01937 1.1e-305 ybiT S abc transporter atp-binding protein
AAPGIAML_01938 0.0 XK27_10405 S Bacterial membrane protein YfhO
AAPGIAML_01942 4e-119 yoaK S Protein of unknown function (DUF1275)
AAPGIAML_01943 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AAPGIAML_01944 9.2e-207 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
AAPGIAML_01945 7.7e-135 parB K Belongs to the ParB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)