ORF_ID e_value Gene_name EC_number CAZy COGs Description
HICMHLEF_00001 8.2e-67
HICMHLEF_00002 3.3e-172 ccpB 5.1.1.1 K lacI family
HICMHLEF_00003 1.2e-34 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
HICMHLEF_00004 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
HICMHLEF_00005 2.6e-60 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HICMHLEF_00006 3.3e-75 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HICMHLEF_00007 7.6e-28 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HICMHLEF_00008 1.8e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HICMHLEF_00009 9.8e-225 mdtG EGP Major facilitator Superfamily
HICMHLEF_00010 6.9e-150 K acetyltransferase
HICMHLEF_00011 6.8e-90
HICMHLEF_00012 3.7e-85 yceI G Sugar (and other) transporter
HICMHLEF_00013 2.3e-122 yceI G Sugar (and other) transporter
HICMHLEF_00014 1.8e-226
HICMHLEF_00015 8.9e-289 2.4.1.52 GT4 M Glycosyl transferases group 1
HICMHLEF_00016 3.3e-302 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HICMHLEF_00017 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HICMHLEF_00018 2e-52 yqaB S Acetyltransferase (GNAT) domain
HICMHLEF_00019 1.6e-32 yqaB S Acetyltransferase (GNAT) domain
HICMHLEF_00020 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HICMHLEF_00021 4.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HICMHLEF_00022 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HICMHLEF_00023 5.2e-240 ytoI K DRTGG domain
HICMHLEF_00024 4.3e-54 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HICMHLEF_00025 5.8e-103 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HICMHLEF_00026 1.5e-10 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HICMHLEF_00027 4.3e-228 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HICMHLEF_00028 2e-155
HICMHLEF_00030 2.6e-155 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HICMHLEF_00031 8.7e-201 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HICMHLEF_00032 1.2e-56 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HICMHLEF_00033 3.1e-201
HICMHLEF_00034 4e-43 yrzL S Belongs to the UPF0297 family
HICMHLEF_00036 1.3e-61 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HICMHLEF_00037 2.3e-53 yrzB S Belongs to the UPF0473 family
HICMHLEF_00038 2e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HICMHLEF_00039 8.6e-93 cvpA S Colicin V production protein
HICMHLEF_00040 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HICMHLEF_00041 4.5e-103 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HICMHLEF_00042 6.6e-53 trxA O Belongs to the thioredoxin family
HICMHLEF_00043 9.4e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HICMHLEF_00044 2.9e-188 dltB M MBOAT, membrane-bound O-acyltransferase family
HICMHLEF_00045 4e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HICMHLEF_00046 1.2e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HICMHLEF_00047 1.1e-83 yslB S Protein of unknown function (DUF2507)
HICMHLEF_00048 3e-198 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HICMHLEF_00049 3.7e-69 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HICMHLEF_00050 2.9e-60 S Phosphoesterase
HICMHLEF_00051 4.3e-25 S Phosphoesterase
HICMHLEF_00052 8.9e-133 gla U Major intrinsic protein
HICMHLEF_00053 8.7e-84 ykuL S CBS domain
HICMHLEF_00054 4.2e-156 XK27_00890 S Domain of unknown function (DUF368)
HICMHLEF_00055 1.2e-155 ykuT M mechanosensitive ion channel
HICMHLEF_00058 4.9e-74 ytxH S YtxH-like protein
HICMHLEF_00059 1.9e-92 niaR S 3H domain
HICMHLEF_00060 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HICMHLEF_00061 2.3e-179 ccpA K catabolite control protein A
HICMHLEF_00062 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
HICMHLEF_00063 1.9e-07
HICMHLEF_00064 5.2e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HICMHLEF_00065 5.7e-135 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HICMHLEF_00066 4.2e-272 pepV 3.5.1.18 E dipeptidase PepV
HICMHLEF_00067 6.8e-256 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HICMHLEF_00068 2.1e-54
HICMHLEF_00069 6.4e-188 yibE S overlaps another CDS with the same product name
HICMHLEF_00070 1.1e-80 yibF S overlaps another CDS with the same product name
HICMHLEF_00071 1.1e-37 S Calcineurin-like phosphoesterase
HICMHLEF_00072 2.7e-48 S Calcineurin-like phosphoesterase
HICMHLEF_00073 3.8e-39 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HICMHLEF_00074 9.9e-191 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HICMHLEF_00075 4.7e-40 yutD S Protein of unknown function (DUF1027)
HICMHLEF_00076 1.7e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HICMHLEF_00077 5.6e-115 S Protein of unknown function (DUF1461)
HICMHLEF_00078 2.3e-116 dedA S SNARE-like domain protein
HICMHLEF_00079 1.5e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HICMHLEF_00080 7.9e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HICMHLEF_00081 3.8e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HICMHLEF_00082 4.3e-64 yugI 5.3.1.9 J general stress protein
HICMHLEF_00083 6.1e-35
HICMHLEF_00084 2.4e-71 S COG NOG38524 non supervised orthologous group
HICMHLEF_00085 6.8e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
HICMHLEF_00086 2.9e-43 trxC O Belongs to the thioredoxin family
HICMHLEF_00087 1.6e-89 thrE S Putative threonine/serine exporter
HICMHLEF_00088 1.7e-32 S Threonine/Serine exporter, ThrE
HICMHLEF_00089 6.2e-29 S Threonine/Serine exporter, ThrE
HICMHLEF_00090 1.3e-213 livJ E Receptor family ligand binding region
HICMHLEF_00091 6.7e-151 livH U Branched-chain amino acid transport system / permease component
HICMHLEF_00092 1.7e-120 livM E Branched-chain amino acid transport system / permease component
HICMHLEF_00093 4.7e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
HICMHLEF_00094 1.8e-122 livF E ABC transporter
HICMHLEF_00095 1.2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HICMHLEF_00096 1.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HICMHLEF_00097 3.8e-157 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICMHLEF_00098 1.2e-23 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICMHLEF_00099 3.9e-116 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HICMHLEF_00100 4.4e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HICMHLEF_00101 7.7e-11 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HICMHLEF_00102 7.6e-109 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HICMHLEF_00103 2.1e-144 p75 M NlpC P60 family protein
HICMHLEF_00104 4.1e-231 nox 1.6.3.4 C NADH oxidase
HICMHLEF_00105 2e-258 lacE-1 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HICMHLEF_00106 3e-143 K CAT RNA binding domain
HICMHLEF_00107 5.2e-57 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HICMHLEF_00108 1.2e-234 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HICMHLEF_00109 7.2e-55 sepS16B
HICMHLEF_00110 2.3e-73 sepS16B
HICMHLEF_00111 1.2e-229 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HICMHLEF_00112 2.6e-200 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HICMHLEF_00113 2.1e-238 malE G Bacterial extracellular solute-binding protein
HICMHLEF_00114 1.5e-82
HICMHLEF_00115 2.6e-296 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00116 5.4e-51 frvA 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00117 5.7e-240 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HICMHLEF_00118 3.7e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
HICMHLEF_00119 3.4e-129 XK27_08435 K UTRA
HICMHLEF_00120 1.8e-90 agaS G SIS domain
HICMHLEF_00121 1.4e-116 agaS G SIS domain
HICMHLEF_00122 8.5e-133 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HICMHLEF_00123 3.2e-80 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HICMHLEF_00124 0.0 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
HICMHLEF_00125 2.4e-71 pts36C G PTS system sugar-specific permease component
HICMHLEF_00126 2.2e-10 pts36C G PTS system sugar-specific permease component
HICMHLEF_00127 3.6e-42 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00128 3e-68 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00129 5e-29 K DeoR C terminal sensor domain
HICMHLEF_00130 6.4e-22 K DeoR C terminal sensor domain
HICMHLEF_00131 1.8e-38 K DeoR C terminal sensor domain
HICMHLEF_00133 5.9e-149 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HICMHLEF_00134 3.1e-77 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HICMHLEF_00135 1.2e-166 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HICMHLEF_00136 3.8e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HICMHLEF_00137 4.5e-285 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HICMHLEF_00138 8.8e-219 iolF EGP Major facilitator Superfamily
HICMHLEF_00139 4.1e-192 rhaR K helix_turn_helix, arabinose operon control protein
HICMHLEF_00140 4.2e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HICMHLEF_00141 1.4e-65 S Protein of unknown function (DUF1093)
HICMHLEF_00142 2.4e-38
HICMHLEF_00143 1.1e-73
HICMHLEF_00144 6.7e-95 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HICMHLEF_00145 2.6e-219 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HICMHLEF_00146 3.7e-180 plyA3 M Right handed beta helix region
HICMHLEF_00147 3.5e-112 plyA3 M Right handed beta helix region
HICMHLEF_00148 2.9e-81
HICMHLEF_00149 3.5e-33 M Heparinase II/III N-terminus
HICMHLEF_00150 8.6e-210 M Heparinase II/III N-terminus
HICMHLEF_00152 3.5e-66 G PTS system fructose IIA component
HICMHLEF_00153 3.6e-143 agaD G PTS system mannose/fructose/sorbose family IID component
HICMHLEF_00154 1.6e-48 G PTS system sorbose-specific iic component
HICMHLEF_00155 1e-41 G PTS system sorbose-specific iic component
HICMHLEF_00156 3.5e-80 agaV 2.7.1.191 G PTS system sorbose subfamily IIB component
HICMHLEF_00157 1.3e-191 ugl 3.2.1.180 GH88 S Glycosyl Hydrolase Family 88
HICMHLEF_00158 3e-22 K Bacterial transcriptional regulator
HICMHLEF_00159 2.9e-63 K Bacterial transcriptional regulator
HICMHLEF_00160 1.7e-143 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HICMHLEF_00161 1e-137 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HICMHLEF_00162 2.3e-87 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HICMHLEF_00163 1.8e-152 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HICMHLEF_00164 8.7e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HICMHLEF_00165 2e-208 CP_0954 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
HICMHLEF_00166 4.9e-121 CP_0954 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
HICMHLEF_00167 1e-31 CP_0954 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
HICMHLEF_00168 5.8e-198 rafA 3.2.1.22 G Melibiase
HICMHLEF_00169 2.7e-40 2.7.1.191 G PTS system sorbose subfamily IIB component
HICMHLEF_00170 3.1e-65 G PTS system mannose/fructose/sorbose family IID component
HICMHLEF_00171 4.4e-64 G PTS system sorbose-specific iic component
HICMHLEF_00172 2.7e-22 2.7.1.191 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HICMHLEF_00173 4.1e-08 araR K transcriptional
HICMHLEF_00174 1.2e-36 araR K helix_turn_helix gluconate operon transcriptional repressor
HICMHLEF_00175 2.2e-215 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HICMHLEF_00176 2.5e-20 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HICMHLEF_00177 3.6e-296 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HICMHLEF_00178 8.3e-208 V ABC-type multidrug transport system, ATPase and permease components
HICMHLEF_00179 6.9e-108 K Transcriptional activator, Rgg GadR MutR family
HICMHLEF_00180 4.5e-124 K Helix-turn-helix domain, rpiR family
HICMHLEF_00181 5.2e-60 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HICMHLEF_00182 1.1e-10 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HICMHLEF_00183 3.7e-137 4.1.2.14 S KDGP aldolase
HICMHLEF_00184 1.2e-202 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
HICMHLEF_00185 5.3e-121 dho 3.5.2.3 S Amidohydrolase family
HICMHLEF_00186 5.3e-81 dho 3.5.2.3 S Amidohydrolase family
HICMHLEF_00187 1e-106 S Domain of unknown function (DUF4310)
HICMHLEF_00188 5.9e-135 S Domain of unknown function (DUF4311)
HICMHLEF_00189 1.2e-29 S Domain of unknown function (DUF4312)
HICMHLEF_00190 3.4e-61 S Glycine-rich SFCGS
HICMHLEF_00191 1.5e-53 S PRD domain
HICMHLEF_00192 0.0 K Mga helix-turn-helix domain
HICMHLEF_00193 1.6e-73 tal 2.2.1.2 H Pfam:Transaldolase
HICMHLEF_00194 3.4e-62 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HICMHLEF_00195 1.6e-194 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HICMHLEF_00196 2.2e-102 srlA G PTS system enzyme II sorbitol-specific factor
HICMHLEF_00197 1.4e-87 gutM K Glucitol operon activator protein (GutM)
HICMHLEF_00198 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HICMHLEF_00199 2.5e-144 IQ NAD dependent epimerase/dehydratase family
HICMHLEF_00200 2.5e-24 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HICMHLEF_00201 6.5e-12 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
HICMHLEF_00202 1.6e-137 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HICMHLEF_00203 5.3e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HICMHLEF_00204 5.4e-167 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HICMHLEF_00205 4.9e-137 repA K DeoR C terminal sensor domain
HICMHLEF_00206 1.6e-114 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HICMHLEF_00207 1.4e-44 sgaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00208 4.5e-26 ulaA S PTS system sugar-specific permease component
HICMHLEF_00209 1.9e-120 ulaA S PTS system sugar-specific permease component
HICMHLEF_00210 6.5e-102 ulaA S PTS system sugar-specific permease component
HICMHLEF_00211 3.6e-79 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00212 1.2e-213 ulaG S Beta-lactamase superfamily domain
HICMHLEF_00214 0.0 O Belongs to the peptidase S8 family
HICMHLEF_00215 1.3e-22 O Belongs to the peptidase S8 family
HICMHLEF_00216 2.6e-42
HICMHLEF_00217 1.6e-155 bglK_1 GK ROK family
HICMHLEF_00218 1.1e-62 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HICMHLEF_00219 2.7e-47 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
HICMHLEF_00220 4.1e-245 3.5.1.18 E Peptidase family M20/M25/M40
HICMHLEF_00221 6.3e-31 ymfC K UTRA
HICMHLEF_00222 6.8e-84 ymfC K UTRA
HICMHLEF_00223 3.3e-47 uhpT EGP Major facilitator Superfamily
HICMHLEF_00224 2e-155 uhpT EGP Major facilitator Superfamily
HICMHLEF_00225 4.7e-204 3.2.1.51 GH29 G Alpha-L-fucosidase
HICMHLEF_00226 7.6e-91 yjgM K Acetyltransferase (GNAT) domain
HICMHLEF_00227 3.7e-111 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HICMHLEF_00229 2.8e-97 K Helix-turn-helix domain
HICMHLEF_00230 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
HICMHLEF_00231 1.5e-258 sca1 G Belongs to the glycosyl hydrolase 31 family
HICMHLEF_00232 1.5e-99 3.6.1.13, 3.6.1.55 F NUDIX domain
HICMHLEF_00233 9.9e-108 pncA Q Isochorismatase family
HICMHLEF_00234 9.5e-264 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HICMHLEF_00235 3.6e-131 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HICMHLEF_00236 1.6e-67 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HICMHLEF_00237 6.4e-241 ugpB G Bacterial extracellular solute-binding protein
HICMHLEF_00238 2.2e-148 ugpE G ABC transporter permease
HICMHLEF_00239 4.7e-163 ugpA P ABC-type sugar transport systems, permease components
HICMHLEF_00240 9.5e-211 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HICMHLEF_00241 5.1e-224 EGP Major facilitator Superfamily
HICMHLEF_00242 7.6e-146 3.5.2.6 V Beta-lactamase enzyme family
HICMHLEF_00243 4.5e-158 blaA6 V Beta-lactamase
HICMHLEF_00244 2.9e-146 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HICMHLEF_00245 6.9e-162 ybbH_2 K Helix-turn-helix domain, rpiR family
HICMHLEF_00246 7.6e-80 2.7.1.191 G PTS system sorbose subfamily IIB component
HICMHLEF_00247 4.1e-37 G PTS system mannose/fructose/sorbose family IID component
HICMHLEF_00248 3.5e-94 G PTS system mannose/fructose/sorbose family IID component
HICMHLEF_00249 7.1e-88 G PTS system sorbose-specific iic component
HICMHLEF_00252 2.7e-202 S endonuclease exonuclease phosphatase family protein
HICMHLEF_00254 2.4e-150 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HICMHLEF_00255 9.1e-30 1.1.1.346 S reductase
HICMHLEF_00256 5.9e-91 1.1.1.346 S reductase
HICMHLEF_00257 2.5e-74 adhR K helix_turn_helix, mercury resistance
HICMHLEF_00258 9.4e-142 Q Methyltransferase
HICMHLEF_00259 1.8e-27 sugE U Multidrug resistance protein
HICMHLEF_00260 1.1e-13 sugE U Multidrug resistance protein
HICMHLEF_00262 1.2e-145 V ABC transporter transmembrane region
HICMHLEF_00263 1e-56
HICMHLEF_00264 5.9e-36
HICMHLEF_00265 2.5e-107 S alpha beta
HICMHLEF_00266 6.6e-79 MA20_25245 K FR47-like protein
HICMHLEF_00267 1.7e-77 hisB 2.7.7.71, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 5.3.1.28, 6.3.2.10 GT9 E HAD-hyrolase-like
HICMHLEF_00268 2.7e-132 wzb 3.1.3.48 T Tyrosine phosphatase family
HICMHLEF_00269 3.5e-85 K Acetyltransferase (GNAT) domain
HICMHLEF_00270 1.3e-122
HICMHLEF_00271 4.2e-56 6.3.3.2 S ASCH
HICMHLEF_00272 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HICMHLEF_00273 3.5e-197 ybiR P Citrate transporter
HICMHLEF_00274 6.8e-100
HICMHLEF_00275 7.3e-250 E Peptidase dimerisation domain
HICMHLEF_00276 7e-267 E ABC transporter, substratebinding protein
HICMHLEF_00277 1.3e-133
HICMHLEF_00278 0.0 K helix_turn_helix, arabinose operon control protein
HICMHLEF_00279 3.9e-282 G MFS/sugar transport protein
HICMHLEF_00280 8.1e-271 S Glycosyl hydrolase family 115
HICMHLEF_00281 4e-76 S Glycosyl hydrolase family 115
HICMHLEF_00282 0.0 cadA P P-type ATPase
HICMHLEF_00283 2.7e-76 hsp3 O Hsp20/alpha crystallin family
HICMHLEF_00284 5.9e-70 S Iron-sulphur cluster biosynthesis
HICMHLEF_00285 2.9e-206 htrA 3.4.21.107 O serine protease
HICMHLEF_00286 1.8e-07
HICMHLEF_00287 2.7e-154 vicX 3.1.26.11 S domain protein
HICMHLEF_00288 1.3e-140 yycI S YycH protein
HICMHLEF_00289 1.8e-259 yycH S YycH protein
HICMHLEF_00290 0.0 vicK 2.7.13.3 T Histidine kinase
HICMHLEF_00291 8.1e-131 K response regulator
HICMHLEF_00292 2.7e-123 S Alpha/beta hydrolase family
HICMHLEF_00293 9.3e-259 arpJ P ABC transporter permease
HICMHLEF_00294 8.8e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HICMHLEF_00295 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
HICMHLEF_00296 7e-214 S Bacterial protein of unknown function (DUF871)
HICMHLEF_00297 1.2e-73 S Domain of unknown function (DUF3284)
HICMHLEF_00298 3.8e-238 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICMHLEF_00299 6.9e-130 K UbiC transcription regulator-associated domain protein
HICMHLEF_00300 3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00301 4.9e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HICMHLEF_00302 1.7e-107 speG J Acetyltransferase (GNAT) domain
HICMHLEF_00303 1.9e-81 F NUDIX domain
HICMHLEF_00304 2.5e-89 S AAA domain
HICMHLEF_00305 2.3e-113 ycaC Q Isochorismatase family
HICMHLEF_00306 2.9e-57 ydiC1 EGP Major Facilitator Superfamily
HICMHLEF_00307 6.6e-185 ydiC1 EGP Major Facilitator Superfamily
HICMHLEF_00308 6.5e-210 yeaN P Transporter, major facilitator family protein
HICMHLEF_00309 5e-173 iolS C Aldo keto reductase
HICMHLEF_00310 4.4e-64 manO S Domain of unknown function (DUF956)
HICMHLEF_00311 3.8e-105 manN G system, mannose fructose sorbose family IID component
HICMHLEF_00312 3.2e-55 manN G system, mannose fructose sorbose family IID component
HICMHLEF_00313 1.6e-122 manY G PTS system
HICMHLEF_00314 1.3e-182 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HICMHLEF_00315 3.3e-84 EGP Major facilitator Superfamily
HICMHLEF_00316 1.2e-121 EGP Major facilitator Superfamily
HICMHLEF_00317 6.7e-187 K Helix-turn-helix XRE-family like proteins
HICMHLEF_00318 2.3e-148 K Helix-turn-helix XRE-family like proteins
HICMHLEF_00319 5.7e-147 K sequence-specific DNA binding
HICMHLEF_00324 4.7e-307 ybfG M peptidoglycan-binding domain-containing protein
HICMHLEF_00325 6.8e-36 ybfG M peptidoglycan-binding domain-containing protein
HICMHLEF_00327 4e-287 glnP P ABC transporter permease
HICMHLEF_00328 2.4e-133 glnQ E ABC transporter, ATP-binding protein
HICMHLEF_00329 1.7e-39
HICMHLEF_00330 2e-236 malE G Bacterial extracellular solute-binding protein
HICMHLEF_00331 9.1e-16
HICMHLEF_00332 4.8e-131 S Protein of unknown function (DUF975)
HICMHLEF_00333 6.8e-08 yqkB S Iron-sulphur cluster biosynthesis
HICMHLEF_00334 1.2e-52
HICMHLEF_00335 6.3e-51 S Bacterial PH domain
HICMHLEF_00336 1.4e-284 ydbT S Bacterial PH domain
HICMHLEF_00337 3.8e-142 S AAA ATPase domain
HICMHLEF_00338 4.3e-166 yniA G Phosphotransferase enzyme family
HICMHLEF_00339 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HICMHLEF_00340 1.1e-262 glnP P ABC transporter
HICMHLEF_00341 3.3e-264 glnP P ABC transporter
HICMHLEF_00342 8.3e-99 ydaF J Acetyltransferase (GNAT) domain
HICMHLEF_00343 6.3e-103 S Stage II sporulation protein M
HICMHLEF_00344 1.9e-167 yeaC S ATPase family associated with various cellular activities (AAA)
HICMHLEF_00345 7.1e-133 yeaD S Protein of unknown function DUF58
HICMHLEF_00346 1.7e-193 yebA E Transglutaminase/protease-like homologues
HICMHLEF_00347 7e-214 lsgC M Glycosyl transferases group 1
HICMHLEF_00348 4.6e-255 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HICMHLEF_00351 6.3e-197 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HICMHLEF_00352 6.1e-144 maeN C 2-hydroxycarboxylate transporter family
HICMHLEF_00353 1.7e-70 maeN C 2-hydroxycarboxylate transporter family
HICMHLEF_00354 1.8e-268 dcuS 2.7.13.3 T Single cache domain 3
HICMHLEF_00355 6.3e-100 dpiA KT cheY-homologous receiver domain
HICMHLEF_00356 5.5e-95
HICMHLEF_00357 3.7e-118 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HICMHLEF_00359 1.8e-148 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
HICMHLEF_00360 1.4e-68
HICMHLEF_00361 1.6e-131 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
HICMHLEF_00362 5.8e-169 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HICMHLEF_00364 8.8e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HICMHLEF_00365 6.9e-14 D Alpha beta
HICMHLEF_00366 1.3e-139 D Alpha beta
HICMHLEF_00367 5.9e-185 lipA I Carboxylesterase family
HICMHLEF_00368 7.3e-186 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HICMHLEF_00369 1e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICMHLEF_00370 0.0 mtlR K Mga helix-turn-helix domain
HICMHLEF_00371 2.2e-171 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00372 7.4e-141 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00373 9.3e-118 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HICMHLEF_00374 3.3e-149 S haloacid dehalogenase-like hydrolase
HICMHLEF_00375 2.8e-44
HICMHLEF_00376 2e-14
HICMHLEF_00377 4.1e-136
HICMHLEF_00378 5.7e-222 spiA K IrrE N-terminal-like domain
HICMHLEF_00379 5.6e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HICMHLEF_00380 2e-126 V ABC transporter
HICMHLEF_00381 8.1e-208 bacI V MacB-like periplasmic core domain
HICMHLEF_00382 1.1e-90 1.6.5.5 C nadph quinone reductase
HICMHLEF_00383 3.6e-74 K Helix-turn-helix XRE-family like proteins
HICMHLEF_00384 6.4e-30
HICMHLEF_00385 1.1e-180
HICMHLEF_00386 0.0 M Leucine rich repeats (6 copies)
HICMHLEF_00387 1.4e-181 M Leucine rich repeats (6 copies)
HICMHLEF_00388 1.4e-52 M Leucine rich repeats (6 copies)
HICMHLEF_00389 6.7e-223 mtnE 2.6.1.83 E Aminotransferase
HICMHLEF_00390 1.4e-139 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HICMHLEF_00391 2.7e-149 M NLPA lipoprotein
HICMHLEF_00394 2.8e-60 K Psort location Cytoplasmic, score
HICMHLEF_00395 5.8e-197 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
HICMHLEF_00399 2e-222 amd 3.5.1.47 E Peptidase family M20/M25/M40
HICMHLEF_00400 6.6e-21 S Threonine/Serine exporter, ThrE
HICMHLEF_00401 2.4e-46 S Threonine/Serine exporter, ThrE
HICMHLEF_00402 3.2e-133 thrE S Putative threonine/serine exporter
HICMHLEF_00404 7.2e-30
HICMHLEF_00405 2.3e-274 V ABC transporter transmembrane region
HICMHLEF_00406 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HICMHLEF_00407 5.8e-172 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HICMHLEF_00408 2.2e-58 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HICMHLEF_00409 1.3e-137 jag S R3H domain protein
HICMHLEF_00410 6.4e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HICMHLEF_00411 1.9e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HICMHLEF_00413 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HICMHLEF_00414 3.5e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HICMHLEF_00415 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HICMHLEF_00417 1.4e-115 L Transposase and inactivated derivatives, IS30 family
HICMHLEF_00418 4.8e-188 pts36C G iic component
HICMHLEF_00419 8.1e-09 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00420 4.1e-30 pts36A 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00421 5.9e-63 K DeoR C terminal sensor domain
HICMHLEF_00422 1.3e-54 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HICMHLEF_00423 1.1e-57 gntR K rpiR family
HICMHLEF_00424 5.1e-31 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00425 4e-168 S PTS system sugar-specific permease component
HICMHLEF_00427 2.2e-132 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
HICMHLEF_00428 9.3e-67 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HICMHLEF_00429 6.6e-219 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HICMHLEF_00430 1.6e-210 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HICMHLEF_00431 3.2e-38 glvR K Helix-turn-helix domain, rpiR family
HICMHLEF_00433 2.8e-20 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HICMHLEF_00434 3e-44 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HICMHLEF_00435 9.4e-52 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HICMHLEF_00436 7.5e-91 K antiterminator
HICMHLEF_00437 1.2e-234 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
HICMHLEF_00438 2e-232 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HICMHLEF_00439 1.1e-230 manR K PRD domain
HICMHLEF_00441 1.1e-25 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HICMHLEF_00442 1.9e-167 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HICMHLEF_00443 8e-66 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00444 5.7e-44 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00445 1.2e-162 G Phosphotransferase System
HICMHLEF_00446 1.7e-43 G Domain of unknown function (DUF4432)
HICMHLEF_00447 1.2e-63 G Domain of unknown function (DUF4432)
HICMHLEF_00448 2.4e-111 5.3.1.15 S Pfam:DUF1498
HICMHLEF_00449 6.4e-199 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HICMHLEF_00450 1.5e-10 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
HICMHLEF_00451 1.4e-165 2.7.1.199, 2.7.1.208 G pts system
HICMHLEF_00452 1.1e-80 celG 3.5.1.105 G Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
HICMHLEF_00453 7.8e-175 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HICMHLEF_00454 1.2e-28 glvR K DNA-binding transcription factor activity
HICMHLEF_00455 7.2e-61 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00456 9e-268 frvB 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00457 2.2e-189 malY 4.4.1.8 E Aminotransferase class I and II
HICMHLEF_00458 1.1e-218 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00459 9.6e-64 kdsD 5.3.1.13 M SIS domain
HICMHLEF_00460 7.5e-45 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00461 3e-31 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00462 4.3e-183 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HICMHLEF_00463 7e-87 4.3.3.7 E Dihydrodipicolinate synthetase family
HICMHLEF_00464 2.1e-59 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HICMHLEF_00465 9.8e-199 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00466 2.4e-18 hxlR K Transcriptional regulator, HxlR family
HICMHLEF_00467 6.7e-58 pnb C nitroreductase
HICMHLEF_00468 7.2e-58
HICMHLEF_00469 5.4e-07 K DNA-templated transcription, initiation
HICMHLEF_00470 1.3e-17 S YvrJ protein family
HICMHLEF_00471 4.8e-145 yqfZ 3.2.1.17 M hydrolase, family 25
HICMHLEF_00472 9.6e-86 ygfC K Bacterial regulatory proteins, tetR family
HICMHLEF_00473 1.1e-184 hrtB V ABC transporter permease
HICMHLEF_00474 1.3e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HICMHLEF_00475 1.1e-261 npr 1.11.1.1 C NADH oxidase
HICMHLEF_00476 2.8e-54 S hydrolase
HICMHLEF_00477 2.4e-74 S hydrolase
HICMHLEF_00478 7.6e-45 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HICMHLEF_00479 4.6e-164 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HICMHLEF_00480 3.3e-75 2.7.1.191 G PTS system sorbose subfamily IIB component
HICMHLEF_00481 3.4e-47 G PTS system sorbose-specific iic component
HICMHLEF_00482 2e-64 G PTS system sorbose-specific iic component
HICMHLEF_00483 1.2e-141 G PTS system mannose/fructose/sorbose family IID component
HICMHLEF_00484 5.2e-266 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HICMHLEF_00485 7.6e-86 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HICMHLEF_00486 6.9e-43 2.7.1.191 G PTS system fructose IIA component
HICMHLEF_00487 2.3e-309 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HICMHLEF_00488 1.9e-136 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HICMHLEF_00490 1.9e-19
HICMHLEF_00492 1.3e-129 metQ_4 P Belongs to the nlpA lipoprotein family
HICMHLEF_00493 1.8e-90 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HICMHLEF_00494 1.9e-88 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HICMHLEF_00495 3.1e-173
HICMHLEF_00496 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HICMHLEF_00497 9.4e-17
HICMHLEF_00498 4e-104 K Bacterial regulatory proteins, tetR family
HICMHLEF_00499 9.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
HICMHLEF_00500 1.8e-99 dhaL 2.7.1.121 S Dak2
HICMHLEF_00501 1.3e-84 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HICMHLEF_00502 1.3e-85 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HICMHLEF_00503 1.2e-76 ohr O OsmC-like protein
HICMHLEF_00504 5.6e-20
HICMHLEF_00505 2.8e-08
HICMHLEF_00509 1.5e-09
HICMHLEF_00510 2.8e-252 L Exonuclease
HICMHLEF_00511 6.5e-28 relB L RelB antitoxin
HICMHLEF_00512 4.4e-18
HICMHLEF_00513 1.2e-48 K Helix-turn-helix domain
HICMHLEF_00514 4.8e-205 yceJ EGP Major facilitator Superfamily
HICMHLEF_00515 5.2e-104 tag 3.2.2.20 L glycosylase
HICMHLEF_00516 2.5e-77 L Resolvase, N-terminal
HICMHLEF_00517 1.2e-86 tnpB L Putative transposase DNA-binding domain
HICMHLEF_00518 6.5e-105 tnpB L Putative transposase DNA-binding domain
HICMHLEF_00520 9.1e-33
HICMHLEF_00521 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HICMHLEF_00522 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HICMHLEF_00523 6.1e-45
HICMHLEF_00524 8.2e-153 V Beta-lactamase
HICMHLEF_00525 7.3e-192 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HICMHLEF_00526 5.6e-43 H Protein of unknown function (DUF1698)
HICMHLEF_00527 1.6e-54 H Protein of unknown function (DUF1698)
HICMHLEF_00528 1.7e-140 puuD S peptidase C26
HICMHLEF_00529 1.6e-59 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HICMHLEF_00530 1.6e-29 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HICMHLEF_00531 1.3e-78 K Psort location Cytoplasmic, score
HICMHLEF_00532 2.1e-257 6.3.1.2 E Glutamine synthetase N-terminal domain
HICMHLEF_00533 3.1e-26 S Amidohydrolase
HICMHLEF_00534 2.6e-106 S Amidohydrolase
HICMHLEF_00535 1.3e-50 S Amidohydrolase
HICMHLEF_00536 8e-227 E Amino acid permease
HICMHLEF_00537 2.5e-74 K helix_turn_helix, mercury resistance
HICMHLEF_00538 6.6e-137 morA2 S reductase
HICMHLEF_00539 2.8e-193 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HICMHLEF_00540 4e-59 hxlR K Transcriptional regulator, HxlR family
HICMHLEF_00541 1.5e-127 S membrane transporter protein
HICMHLEF_00542 3.6e-197
HICMHLEF_00543 4.6e-129 XK27_12140 V ATPases associated with a variety of cellular activities
HICMHLEF_00544 3.5e-109 S Psort location CytoplasmicMembrane, score
HICMHLEF_00545 4e-162 S Psort location CytoplasmicMembrane, score
HICMHLEF_00546 1.2e-13 K Transcriptional regulatory protein, C terminal
HICMHLEF_00547 1.1e-103 K Transcriptional regulatory protein, C terminal
HICMHLEF_00548 5.1e-196 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HICMHLEF_00549 1.9e-161 V ATPases associated with a variety of cellular activities
HICMHLEF_00550 1e-187
HICMHLEF_00551 0.0 pepN 3.4.11.2 E aminopeptidase
HICMHLEF_00552 2.2e-51 ycaM E Amino Acid
HICMHLEF_00553 8e-216 ycaM E amino acid
HICMHLEF_00554 5.5e-198 G MFS/sugar transport protein
HICMHLEF_00555 6e-72 S Protein of unknown function (DUF1440)
HICMHLEF_00556 2.3e-161 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HICMHLEF_00557 1e-173 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HICMHLEF_00559 1e-36
HICMHLEF_00560 1.5e-95
HICMHLEF_00562 4.5e-36 metC 4.4.1.8 E cystathionine
HICMHLEF_00563 2.7e-127 metC 4.4.1.8 E cystathionine
HICMHLEF_00564 1.3e-38 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HICMHLEF_00565 1.3e-79 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HICMHLEF_00566 2.2e-120 tcyB E ABC transporter
HICMHLEF_00567 2.2e-117
HICMHLEF_00568 8.6e-108 brnQ U Component of the transport system for branched-chain amino acids
HICMHLEF_00569 7.2e-134 brnQ U Component of the transport system for branched-chain amino acids
HICMHLEF_00570 4.1e-76 S WxL domain surface cell wall-binding
HICMHLEF_00571 1e-174 S Cell surface protein
HICMHLEF_00572 1.2e-42
HICMHLEF_00573 3.1e-247 XK27_00720 S Leucine-rich repeat (LRR) protein
HICMHLEF_00575 5e-120 S WxL domain surface cell wall-binding
HICMHLEF_00576 4.5e-56
HICMHLEF_00577 2.6e-89 N WxL domain surface cell wall-binding
HICMHLEF_00578 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HICMHLEF_00579 1.6e-166 yicL EG EamA-like transporter family
HICMHLEF_00580 4.4e-300
HICMHLEF_00581 8.5e-145 CcmA5 V ABC transporter
HICMHLEF_00582 6.2e-78 S ECF-type riboflavin transporter, S component
HICMHLEF_00583 6.7e-145 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HICMHLEF_00584 5.2e-164 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
HICMHLEF_00585 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HICMHLEF_00586 0.0 XK27_09600 V ABC transporter, ATP-binding protein
HICMHLEF_00587 6.8e-46 V ABC transporter
HICMHLEF_00588 5.6e-264 V ABC transporter
HICMHLEF_00589 1.2e-117 oxlT P Major Facilitator Superfamily
HICMHLEF_00590 6.3e-79 oxlT P Major Facilitator Superfamily
HICMHLEF_00591 3.2e-127 treR K UTRA
HICMHLEF_00592 4.9e-112 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HICMHLEF_00593 2e-174 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HICMHLEF_00594 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HICMHLEF_00595 2.1e-139 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HICMHLEF_00596 5.5e-57 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HICMHLEF_00597 1.2e-269 yfnA E Amino Acid
HICMHLEF_00598 4.3e-172 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HICMHLEF_00599 3e-125 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HICMHLEF_00600 4.1e-110 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HICMHLEF_00601 4.6e-31 K 'Cold-shock' DNA-binding domain
HICMHLEF_00602 1.3e-70
HICMHLEF_00603 3.5e-76 O OsmC-like protein
HICMHLEF_00604 1.5e-283 lsa S ABC transporter
HICMHLEF_00605 3.9e-113 ylbE GM NAD(P)H-binding
HICMHLEF_00606 3.7e-160 yeaE S Aldo/keto reductase family
HICMHLEF_00607 3.5e-255 yifK E Amino acid permease
HICMHLEF_00608 2.8e-283 S Protein of unknown function (DUF3800)
HICMHLEF_00609 0.0 yjcE P Sodium proton antiporter
HICMHLEF_00610 3.2e-55 S Protein of unknown function (DUF3021)
HICMHLEF_00611 2.8e-68 K LytTr DNA-binding domain
HICMHLEF_00612 6.4e-146 cylB V ABC-2 type transporter
HICMHLEF_00613 1.7e-157 cylA V ABC transporter
HICMHLEF_00614 2.8e-112 S Alpha/beta hydrolase of unknown function (DUF915)
HICMHLEF_00615 6.9e-113 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HICMHLEF_00616 1.2e-52 ybjQ S Belongs to the UPF0145 family
HICMHLEF_00617 1.1e-92 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
HICMHLEF_00618 2e-158 3.5.1.10 C nadph quinone reductase
HICMHLEF_00619 1.4e-220 amt P ammonium transporter
HICMHLEF_00620 2e-157 yfeX P Peroxidase
HICMHLEF_00621 1.5e-118 yhiD S MgtC family
HICMHLEF_00622 9.3e-147 F DNA RNA non-specific endonuclease
HICMHLEF_00624 1.2e-10
HICMHLEF_00625 5.1e-81 ybiT S ABC transporter, ATP-binding protein
HICMHLEF_00626 2.6e-194 ybiT S ABC transporter, ATP-binding protein
HICMHLEF_00627 7.6e-177 mutS L ATPase domain of DNA mismatch repair MUTS family
HICMHLEF_00628 2e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
HICMHLEF_00629 1.6e-128 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HICMHLEF_00630 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HICMHLEF_00631 9.4e-121 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HICMHLEF_00632 4.4e-163 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HICMHLEF_00633 8.9e-65 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
HICMHLEF_00634 3.7e-55 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
HICMHLEF_00635 6.5e-138 lacT K PRD domain
HICMHLEF_00636 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
HICMHLEF_00637 1.5e-216 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HICMHLEF_00638 1.9e-50 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HICMHLEF_00640 6.2e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HICMHLEF_00641 9.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HICMHLEF_00642 6.5e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HICMHLEF_00643 1.5e-162 K Transcriptional regulator
HICMHLEF_00644 1.4e-192 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HICMHLEF_00646 3.3e-70 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00647 1.7e-48 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00648 2.3e-249 gatC G PTS system sugar-specific permease component
HICMHLEF_00650 1.7e-28
HICMHLEF_00651 8.5e-87 V Beta-lactamase
HICMHLEF_00652 6.8e-58 V Beta-lactamase
HICMHLEF_00653 1.3e-125 S Domain of unknown function (DUF4867)
HICMHLEF_00654 3.2e-175 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HICMHLEF_00655 5.6e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HICMHLEF_00656 5.5e-71 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
HICMHLEF_00657 6.1e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
HICMHLEF_00658 1.9e-141 lacR K DeoR C terminal sensor domain
HICMHLEF_00659 1.9e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HICMHLEF_00660 4.3e-211 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HICMHLEF_00661 1.3e-51 sbcC L Putative exonuclease SbcCD, C subunit
HICMHLEF_00662 1.6e-91 sbcC L Putative exonuclease SbcCD, C subunit
HICMHLEF_00663 2.5e-259 sbcC L Putative exonuclease SbcCD, C subunit
HICMHLEF_00664 1.3e-14
HICMHLEF_00665 3.1e-86 hsp1 O Belongs to the small heat shock protein (HSP20) family
HICMHLEF_00666 1.7e-101 mutY L A G-specific adenine glycosylase
HICMHLEF_00667 1.1e-95 mutY L A G-specific adenine glycosylase
HICMHLEF_00668 7.4e-149 cytC6 I alpha/beta hydrolase fold
HICMHLEF_00669 5.9e-121 yrkL S Flavodoxin-like fold
HICMHLEF_00671 1.7e-88 S Short repeat of unknown function (DUF308)
HICMHLEF_00672 1.9e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HICMHLEF_00673 1.4e-46
HICMHLEF_00674 5.5e-98
HICMHLEF_00675 1.7e-06
HICMHLEF_00676 5.2e-116 ywnB S NmrA-like family
HICMHLEF_00679 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
HICMHLEF_00681 8e-166 XK27_00670 S ABC transporter substrate binding protein
HICMHLEF_00682 1.2e-164 XK27_00670 S ABC transporter
HICMHLEF_00683 7.6e-156 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HICMHLEF_00684 5.2e-142 cmpC S ABC transporter, ATP-binding protein
HICMHLEF_00685 4.9e-171 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
HICMHLEF_00686 9.4e-245 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HICMHLEF_00687 9.9e-55 L Transposase and inactivated derivatives, IS30 family
HICMHLEF_00688 2.9e-31 yaaA S S4 domain protein YaaA
HICMHLEF_00689 2e-186 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HICMHLEF_00690 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HICMHLEF_00691 3.1e-117 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HICMHLEF_00692 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HICMHLEF_00693 4.7e-08 ssb_2 L Single-strand binding protein family
HICMHLEF_00699 2.1e-73 ssb_2 L Single-strand binding protein family
HICMHLEF_00700 2.7e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HICMHLEF_00701 7.3e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HICMHLEF_00702 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HICMHLEF_00703 1.5e-91 yhbO 3.5.1.124 S DJ-1/PfpI family
HICMHLEF_00704 9.8e-280 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
HICMHLEF_00705 7.9e-121 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
HICMHLEF_00706 2.1e-28
HICMHLEF_00707 9.2e-108 S CAAX protease self-immunity
HICMHLEF_00708 6e-84 V Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
HICMHLEF_00709 1.1e-161 V ABC transporter
HICMHLEF_00710 5.8e-32 amtB P Ammonium Transporter Family
HICMHLEF_00711 2.4e-136 amtB P Ammonium Transporter Family
HICMHLEF_00712 6.6e-63 P Pyridine nucleotide-disulphide oxidoreductase
HICMHLEF_00713 1.9e-133 P Pyridine nucleotide-disulphide oxidoreductase
HICMHLEF_00714 4e-125 usp 3.5.1.28 CBM50 D CHAP domain
HICMHLEF_00715 0.0 ylbB V ABC transporter permease
HICMHLEF_00716 6.3e-128 macB V ABC transporter, ATP-binding protein
HICMHLEF_00717 3e-96 K transcriptional regulator
HICMHLEF_00718 3.2e-71 supH G Sucrose-6F-phosphate phosphohydrolase
HICMHLEF_00719 1.3e-69 supH G Sucrose-6F-phosphate phosphohydrolase
HICMHLEF_00720 1.4e-45
HICMHLEF_00721 4.1e-128 S membrane transporter protein
HICMHLEF_00722 1.6e-35 S Protein of unknown function (DUF1211)
HICMHLEF_00723 5e-113 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HICMHLEF_00724 2.9e-49
HICMHLEF_00726 1.5e-285 pipD E Dipeptidase
HICMHLEF_00727 7.4e-42 S Membrane
HICMHLEF_00728 2.1e-86
HICMHLEF_00729 1.2e-24
HICMHLEF_00731 6.1e-244 ybfG M peptidoglycan-binding domain-containing protein
HICMHLEF_00732 3.1e-122 azlC E branched-chain amino acid
HICMHLEF_00733 1.5e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HICMHLEF_00734 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HICMHLEF_00735 0.0 M Glycosyl hydrolase family 59
HICMHLEF_00736 1.4e-304 M Glycosyl hydrolase family 59
HICMHLEF_00737 1.4e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HICMHLEF_00738 4.6e-177 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HICMHLEF_00739 9.5e-280 uxaC 5.3.1.12 G glucuronate isomerase
HICMHLEF_00740 3.3e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HICMHLEF_00741 2.6e-296 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
HICMHLEF_00742 7.8e-267 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HICMHLEF_00743 2.8e-89 G Major Facilitator
HICMHLEF_00744 1.1e-130 G Major Facilitator
HICMHLEF_00745 3.7e-114 kdgR K FCD domain
HICMHLEF_00746 4.3e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HICMHLEF_00747 0.0 M Glycosyl hydrolase family 59
HICMHLEF_00748 1.6e-57
HICMHLEF_00749 1.3e-52 S pyridoxamine 5-phosphate
HICMHLEF_00750 1.3e-241 EGP Major facilitator Superfamily
HICMHLEF_00751 6.9e-117 3.1.1.83 I Alpha beta hydrolase
HICMHLEF_00752 2.9e-77 3.1.1.83 I Alpha beta hydrolase
HICMHLEF_00753 1.5e-118 K Bacterial regulatory proteins, tetR family
HICMHLEF_00755 0.0 ydgH S MMPL family
HICMHLEF_00756 1e-105 K Tetracycline repressor, C-terminal all-alpha domain
HICMHLEF_00757 4.3e-122 S Sulfite exporter TauE/SafE
HICMHLEF_00758 2.9e-99 3.5.4.28, 3.5.4.31 F Amidohydrolase family
HICMHLEF_00759 3.7e-77 3.5.4.28, 3.5.4.31 F Amidohydrolase family
HICMHLEF_00760 4.7e-48 3.5.4.28, 3.5.4.31 F Amidohydrolase family
HICMHLEF_00761 1.9e-69 S An automated process has identified a potential problem with this gene model
HICMHLEF_00762 1e-148 S Protein of unknown function (DUF3100)
HICMHLEF_00764 1.9e-110 opuCD P Binding-protein-dependent transport system inner membrane component
HICMHLEF_00765 1.6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HICMHLEF_00766 4.7e-106 opuCB E ABC transporter permease
HICMHLEF_00767 1.2e-214 opuCA E ABC transporter, ATP-binding protein
HICMHLEF_00768 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
HICMHLEF_00769 5.6e-33 copZ P Heavy-metal-associated domain
HICMHLEF_00770 3.6e-100 dps P Belongs to the Dps family
HICMHLEF_00771 3.1e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HICMHLEF_00773 5.5e-101 S CAAX protease self-immunity
HICMHLEF_00774 2.2e-250 manY 2.7.1.191, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00775 1.6e-79 frvA 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_00776 0.0 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HICMHLEF_00777 3.1e-139 K SIS domain
HICMHLEF_00778 4.6e-254 bgl 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HICMHLEF_00779 5.6e-46 bglK_1 2.7.1.2 GK ROK family
HICMHLEF_00780 9.5e-72 bglK_1 2.7.1.2 GK ROK family
HICMHLEF_00781 4.4e-11 bglK_1 2.7.1.2 GK ROK family
HICMHLEF_00782 5.2e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HICMHLEF_00783 4.9e-148 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HICMHLEF_00784 6.9e-59 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HICMHLEF_00785 3.2e-104 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HICMHLEF_00786 3.3e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HICMHLEF_00787 3.2e-181 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HICMHLEF_00789 1.5e-301 norB EGP Major Facilitator
HICMHLEF_00790 8.8e-110 K Bacterial regulatory proteins, tetR family
HICMHLEF_00791 4.3e-116
HICMHLEF_00792 1.8e-157 S ABC-type transport system involved in multi-copper enzyme maturation permease component
HICMHLEF_00793 1.3e-109
HICMHLEF_00794 2.1e-99 V ATPases associated with a variety of cellular activities
HICMHLEF_00795 1.7e-53
HICMHLEF_00796 4.4e-106 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
HICMHLEF_00797 7.7e-135 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HICMHLEF_00798 2.1e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HICMHLEF_00799 4.9e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HICMHLEF_00800 7.2e-18 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HICMHLEF_00801 5.8e-33 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HICMHLEF_00802 5.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HICMHLEF_00803 1.1e-155 lysC 2.7.2.4 E Belongs to the aspartokinase family
HICMHLEF_00804 4.2e-92 lysC 2.7.2.4 E Belongs to the aspartokinase family
HICMHLEF_00805 5.6e-186 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HICMHLEF_00806 2.6e-83 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HICMHLEF_00807 8.8e-104 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HICMHLEF_00808 2.1e-61
HICMHLEF_00809 5e-72 3.6.1.55 L NUDIX domain
HICMHLEF_00810 1.1e-150 EG EamA-like transporter family
HICMHLEF_00813 2.1e-51 L PFAM transposase, IS4 family protein
HICMHLEF_00814 1.4e-105 L PFAM transposase, IS4 family protein
HICMHLEF_00815 9.1e-47 K Tetracyclin repressor, C-terminal all-alpha domain
HICMHLEF_00817 1.5e-55 V ABC-2 type transporter
HICMHLEF_00818 6.8e-80 P ABC-2 family transporter protein
HICMHLEF_00819 7.5e-100 V ABC transporter, ATP-binding protein
HICMHLEF_00820 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HICMHLEF_00821 5.1e-70 rplI J Binds to the 23S rRNA
HICMHLEF_00822 1.7e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HICMHLEF_00823 2.1e-221
HICMHLEF_00824 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HICMHLEF_00825 1.5e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HICMHLEF_00826 6.6e-198 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HICMHLEF_00827 1.9e-122 K Helix-turn-helix domain, rpiR family
HICMHLEF_00828 1.7e-81 K Transcriptional regulator C-terminal region
HICMHLEF_00830 5.4e-127 V ABC transporter, ATP-binding protein
HICMHLEF_00831 5.5e-124 ylbB V ABC transporter permease
HICMHLEF_00832 0.0 ylbB V ABC transporter permease
HICMHLEF_00833 6.7e-206 4.1.1.52 S Amidohydrolase
HICMHLEF_00834 4.9e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HICMHLEF_00836 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HICMHLEF_00837 1.3e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HICMHLEF_00838 4.6e-31 yxaM EGP Major facilitator Superfamily
HICMHLEF_00839 2.1e-23 yxaM EGP Major facilitator Superfamily
HICMHLEF_00840 4.6e-107 yxaM EGP Major facilitator Superfamily
HICMHLEF_00841 2.1e-09 K Helix-turn-helix XRE-family like proteins
HICMHLEF_00842 1.6e-118 K Helix-turn-helix XRE-family like proteins
HICMHLEF_00843 1.6e-26 S Phospholipase_D-nuclease N-terminal
HICMHLEF_00844 6.5e-120 yxlF V ABC transporter
HICMHLEF_00845 1.2e-103 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HICMHLEF_00846 7.5e-104 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HICMHLEF_00847 4.3e-311 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HICMHLEF_00848 9.7e-30
HICMHLEF_00849 1e-56
HICMHLEF_00850 3e-111 K Bacteriophage CI repressor helix-turn-helix domain
HICMHLEF_00851 4.8e-182 yveB 2.7.4.29 I PAP2 superfamily
HICMHLEF_00852 1.2e-207 mccF V LD-carboxypeptidase
HICMHLEF_00853 7.3e-42
HICMHLEF_00854 9.5e-25 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HICMHLEF_00855 8.7e-170 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HICMHLEF_00856 2.1e-39
HICMHLEF_00857 3.8e-111
HICMHLEF_00858 4.7e-35 EGP Major facilitator Superfamily
HICMHLEF_00859 1e-150 EGP Major facilitator Superfamily
HICMHLEF_00860 2.3e-23
HICMHLEF_00861 6.7e-51
HICMHLEF_00862 1.5e-200 T PhoQ Sensor
HICMHLEF_00863 1.6e-120 K Transcriptional regulatory protein, C terminal
HICMHLEF_00864 4.3e-91 ogt 2.1.1.63 L Methyltransferase
HICMHLEF_00865 1.4e-189 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HICMHLEF_00866 5.3e-37 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_00867 5.8e-52 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HICMHLEF_00868 9.1e-50
HICMHLEF_00869 1.6e-252 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICMHLEF_00870 8e-287 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HICMHLEF_00871 4.9e-131 K UTRA
HICMHLEF_00872 5.6e-41
HICMHLEF_00873 2.4e-57 ypaA S Protein of unknown function (DUF1304)
HICMHLEF_00874 6.3e-52 S Protein of unknown function (DUF1516)
HICMHLEF_00875 3e-238 pbuO S permease
HICMHLEF_00876 9e-53 S DsrE/DsrF-like family
HICMHLEF_00877 5.8e-188 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HICMHLEF_00878 1.5e-14
HICMHLEF_00879 5.6e-106 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HICMHLEF_00880 0.0
HICMHLEF_00882 1.1e-123 yqcC S WxL domain surface cell wall-binding
HICMHLEF_00883 1.3e-183 ynjC S Cell surface protein
HICMHLEF_00885 2.6e-99
HICMHLEF_00886 1.7e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HICMHLEF_00887 8.7e-95 emrY EGP Major facilitator Superfamily
HICMHLEF_00888 1.4e-153 emrY EGP Major facilitator Superfamily
HICMHLEF_00889 4.7e-45 merR K MerR HTH family regulatory protein
HICMHLEF_00890 2.9e-12 merR K MerR HTH family regulatory protein
HICMHLEF_00891 1.3e-38 lmrB EGP Major facilitator Superfamily
HICMHLEF_00892 2.6e-217 lmrB EGP Major facilitator Superfamily
HICMHLEF_00893 2.1e-113 S Domain of unknown function (DUF4811)
HICMHLEF_00894 1.5e-67 3.6.1.27 I Acid phosphatase homologues
HICMHLEF_00895 3.8e-42 3.6.1.27 I Acid phosphatase homologues
HICMHLEF_00896 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HICMHLEF_00897 1.4e-127 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HICMHLEF_00898 5.7e-11
HICMHLEF_00899 2.5e-93 ytgP S Polysaccharide biosynthesis protein
HICMHLEF_00900 4.5e-162 ytgP S Polysaccharide biosynthesis protein
HICMHLEF_00901 3.4e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HICMHLEF_00902 3.3e-35 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HICMHLEF_00903 4.1e-51 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HICMHLEF_00904 1.1e-73 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HICMHLEF_00905 2.6e-95 FNV0100 F NUDIX domain
HICMHLEF_00907 4.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HICMHLEF_00908 1.3e-154 malY 4.4.1.8 E Aminotransferase, class I
HICMHLEF_00909 2.9e-60 malY 4.4.1.8 E Aminotransferase, class I
HICMHLEF_00910 1.2e-126 cpdA S Calcineurin-like phosphoesterase
HICMHLEF_00911 1.5e-37 gcvR T Belongs to the UPF0237 family
HICMHLEF_00912 1.3e-243 XK27_08635 S UPF0210 protein
HICMHLEF_00913 1.1e-211 coiA 3.6.4.12 S Competence protein
HICMHLEF_00914 1.5e-115 yjbH Q Thioredoxin
HICMHLEF_00915 1.3e-91 yjbK S CYTH
HICMHLEF_00916 2.7e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
HICMHLEF_00918 1.3e-25 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HICMHLEF_00919 7.1e-49 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HICMHLEF_00920 7.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HICMHLEF_00921 1.2e-202 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HICMHLEF_00922 1.3e-111 cutC P Participates in the control of copper homeostasis
HICMHLEF_00923 1.5e-141 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HICMHLEF_00924 2.3e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HICMHLEF_00925 1.2e-61 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HICMHLEF_00926 2.9e-38 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HICMHLEF_00927 7.4e-191 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HICMHLEF_00928 5.7e-172 corA P CorA-like Mg2+ transporter protein
HICMHLEF_00929 2.4e-153 rrmA 2.1.1.187 H Methyltransferase
HICMHLEF_00930 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HICMHLEF_00931 5.4e-71 WQ51_03320 S Protein of unknown function (DUF1149)
HICMHLEF_00932 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HICMHLEF_00933 1.5e-211 ymfF S Peptidase M16 inactive domain protein
HICMHLEF_00934 2.2e-243 ymfH S Peptidase M16
HICMHLEF_00935 1.1e-127 IQ Enoyl-(Acyl carrier protein) reductase
HICMHLEF_00936 2e-116 ymfM S Helix-turn-helix domain
HICMHLEF_00937 1.6e-103 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HICMHLEF_00938 1.4e-226 cinA 3.5.1.42 S Belongs to the CinA family
HICMHLEF_00939 1.3e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HICMHLEF_00941 1.1e-19 rny S Endoribonuclease that initiates mRNA decay
HICMHLEF_00942 8.7e-162 rny S Endoribonuclease that initiates mRNA decay
HICMHLEF_00943 2.6e-18 rny S Endoribonuclease that initiates mRNA decay
HICMHLEF_00944 9.5e-118 yvyE 3.4.13.9 S YigZ family
HICMHLEF_00945 8.2e-235 comFA L Helicase C-terminal domain protein
HICMHLEF_00946 1.3e-90 comFC S Competence protein
HICMHLEF_00947 5.4e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HICMHLEF_00948 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HICMHLEF_00949 1.7e-166 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HICMHLEF_00950 1e-35 ftsE D ABC transporter
HICMHLEF_00951 1.6e-67 ftsE D ABC transporter
HICMHLEF_00952 9.4e-90 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HICMHLEF_00953 7e-56 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HICMHLEF_00954 2.1e-191 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HICMHLEF_00955 1.7e-99 K response regulator
HICMHLEF_00956 1.1e-77 phoR 2.7.13.3 T Histidine kinase
HICMHLEF_00957 7.4e-203 phoR 2.7.13.3 T Histidine kinase
HICMHLEF_00958 4.4e-155 pstS P Phosphate
HICMHLEF_00959 3.4e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HICMHLEF_00960 1.1e-156 pstA P Phosphate transport system permease protein PstA
HICMHLEF_00961 4.5e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HICMHLEF_00962 7.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HICMHLEF_00963 1e-119 phoU P Plays a role in the regulation of phosphate uptake
HICMHLEF_00964 8.5e-215 yvlB S Putative adhesin
HICMHLEF_00965 4.7e-08
HICMHLEF_00966 2.4e-39 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HICMHLEF_00967 5e-96 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HICMHLEF_00968 1.1e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HICMHLEF_00969 4.1e-193 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HICMHLEF_00970 1.7e-59 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HICMHLEF_00971 3.2e-83 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HICMHLEF_00972 1.2e-84 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HICMHLEF_00973 2.2e-218 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HICMHLEF_00974 6.8e-84 T Transcriptional regulatory protein, C terminal
HICMHLEF_00975 8.9e-115 T His Kinase A (phosphoacceptor) domain
HICMHLEF_00976 1.2e-91 V ABC transporter
HICMHLEF_00977 1.1e-87 V FtsX-like permease family
HICMHLEF_00978 7.4e-48 V FtsX-like permease family
HICMHLEF_00979 1.8e-63 V FtsX-like permease family
HICMHLEF_00980 5.5e-118 yfbR S HD containing hydrolase-like enzyme
HICMHLEF_00981 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HICMHLEF_00982 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HICMHLEF_00983 6.7e-85 S Short repeat of unknown function (DUF308)
HICMHLEF_00984 1.3e-165 rapZ S Displays ATPase and GTPase activities
HICMHLEF_00985 1.1e-47 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HICMHLEF_00986 4.5e-91 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HICMHLEF_00987 2.4e-81 whiA K May be required for sporulation
HICMHLEF_00988 1.7e-78 whiA K May be required for sporulation
HICMHLEF_00989 5.5e-80 ohrR K helix_turn_helix multiple antibiotic resistance protein
HICMHLEF_00990 9.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HICMHLEF_00992 3.6e-188 cggR K Putative sugar-binding domain
HICMHLEF_00993 2.2e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HICMHLEF_00994 2.8e-205 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HICMHLEF_00995 4.1e-92 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HICMHLEF_00996 3.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HICMHLEF_00997 1.2e-64
HICMHLEF_00998 3.7e-293 clcA P chloride
HICMHLEF_00999 2e-32
HICMHLEF_01000 9.3e-31 secG U Preprotein translocase
HICMHLEF_01001 1.9e-115 est 3.1.1.1 S Serine aminopeptidase, S33
HICMHLEF_01002 7.8e-114 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HICMHLEF_01003 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HICMHLEF_01004 3.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HICMHLEF_01005 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HICMHLEF_01006 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HICMHLEF_01007 1e-59 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HICMHLEF_01008 7.7e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HICMHLEF_01009 2.7e-45
HICMHLEF_01010 9.7e-17
HICMHLEF_01011 1.6e-25 ydcG K Transcriptional
HICMHLEF_01012 9.5e-112 YSH1 S Metallo-beta-lactamase superfamily
HICMHLEF_01013 1.3e-82 YSH1 S Metallo-beta-lactamase superfamily
HICMHLEF_01014 4.4e-239 malE G Bacterial extracellular solute-binding protein
HICMHLEF_01015 1.9e-147 malF G Binding-protein-dependent transport system inner membrane component
HICMHLEF_01016 2.6e-166 malG P ABC-type sugar transport systems, permease components
HICMHLEF_01017 1.6e-194 malK P ATPases associated with a variety of cellular activities
HICMHLEF_01018 4.4e-103 3.2.2.20 K Acetyltransferase (GNAT) domain
HICMHLEF_01019 2e-45 yxjI
HICMHLEF_01020 4.6e-37 yxjI
HICMHLEF_01021 2e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
HICMHLEF_01022 4.6e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HICMHLEF_01023 8.4e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HICMHLEF_01024 2.3e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HICMHLEF_01025 5.4e-164 natA S ABC transporter, ATP-binding protein
HICMHLEF_01026 5.7e-19 ysdA CP ABC-2 family transporter protein
HICMHLEF_01027 1.4e-190 ysdA CP ABC-2 family transporter protein
HICMHLEF_01028 5.8e-94 dnaQ 2.7.7.7 L DNA polymerase III
HICMHLEF_01029 1.4e-126 xth 3.1.11.2 L exodeoxyribonuclease III
HICMHLEF_01030 1.3e-165 murB 1.3.1.98 M Cell wall formation
HICMHLEF_01031 1.2e-149 yjcE P Sodium proton antiporter
HICMHLEF_01032 3.2e-220 yjcE P Sodium proton antiporter
HICMHLEF_01033 2.9e-96 puuR K Cupin domain
HICMHLEF_01034 4.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HICMHLEF_01035 2.6e-109 potB P ABC transporter permease
HICMHLEF_01036 1.1e-26 potB P ABC transporter permease
HICMHLEF_01037 6e-85 licT K CAT RNA binding domain
HICMHLEF_01038 0.0 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HICMHLEF_01039 3.4e-96 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HICMHLEF_01040 5.4e-112 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HICMHLEF_01041 5.7e-118 IQ reductase
HICMHLEF_01042 5.7e-115 VPA0052 I ABC-2 family transporter protein
HICMHLEF_01043 4.9e-162 CcmA V ABC transporter
HICMHLEF_01044 8.1e-64 K helix_turn_helix gluconate operon transcriptional repressor
HICMHLEF_01045 1.6e-209 ysdA CP ABC-2 family transporter protein
HICMHLEF_01046 3.7e-128 natA S ABC transporter
HICMHLEF_01047 3.6e-23 natA S ABC transporter
HICMHLEF_01048 1.2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HICMHLEF_01049 7.3e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HICMHLEF_01050 1.5e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HICMHLEF_01051 5.2e-206 S Calcineurin-like phosphoesterase
HICMHLEF_01052 2.2e-08
HICMHLEF_01053 1.1e-253 asnB 6.3.5.4 E Asparagine synthase
HICMHLEF_01054 2.3e-107 asnB 6.3.5.4 E Asparagine synthase
HICMHLEF_01055 2.1e-171 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HICMHLEF_01056 3.1e-83 XK27_06930 V domain protein
HICMHLEF_01057 3.3e-78 XK27_06930 V domain protein
HICMHLEF_01058 2.3e-102 K Bacterial regulatory proteins, tetR family
HICMHLEF_01059 6e-143 S Alpha/beta hydrolase family
HICMHLEF_01060 6.2e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
HICMHLEF_01061 4.2e-217 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HICMHLEF_01062 5.9e-180 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HICMHLEF_01063 1.5e-154 pfoS S Phosphotransferase system, EIIC
HICMHLEF_01064 5.7e-68
HICMHLEF_01065 5.8e-166 yqiK S SPFH domain / Band 7 family
HICMHLEF_01066 2.2e-148 yclM 2.7.2.4 E Belongs to the aspartokinase family
HICMHLEF_01067 6.6e-70 yclM 2.7.2.4 E Belongs to the aspartokinase family
HICMHLEF_01068 1.3e-229 hom 1.1.1.3 E homoserine dehydrogenase
HICMHLEF_01069 1.4e-281 thrC 4.2.3.1 E Threonine synthase
HICMHLEF_01070 1.1e-25 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HICMHLEF_01071 6.9e-50 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HICMHLEF_01072 1.8e-250 yxbA 6.3.1.12 S ATP-grasp enzyme
HICMHLEF_01073 1.6e-66 usp1 T Universal stress protein family
HICMHLEF_01074 4.4e-132 sfsA S Belongs to the SfsA family
HICMHLEF_01075 2.3e-99 gbuA 3.6.3.32 E glycine betaine
HICMHLEF_01076 7.1e-110 gbuA 3.6.3.32 E glycine betaine
HICMHLEF_01077 1.8e-124 proW E glycine betaine
HICMHLEF_01078 7.5e-163 gbuC E glycine betaine
HICMHLEF_01079 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HICMHLEF_01080 1.5e-65 gtcA S Teichoic acid glycosylation protein
HICMHLEF_01081 1.2e-61 srtA 3.4.22.70 M Sortase family
HICMHLEF_01082 2.6e-55 srtA 3.4.22.70 M Sortase family
HICMHLEF_01083 1.5e-181 K AI-2E family transporter
HICMHLEF_01084 6e-31 pbpX1 V Beta-lactamase
HICMHLEF_01085 4.6e-146 pbpX1 V Beta-lactamase
HICMHLEF_01086 4.4e-125 S zinc-ribbon domain
HICMHLEF_01087 3.5e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HICMHLEF_01088 4.3e-40 F NUDIX domain
HICMHLEF_01089 3.5e-103 rmaB K Transcriptional regulator, MarR family
HICMHLEF_01090 6.4e-183
HICMHLEF_01091 1.2e-159 S Putative esterase
HICMHLEF_01093 1.2e-11 S response to antibiotic
HICMHLEF_01094 3.7e-67 K MarR family
HICMHLEF_01095 3.9e-26
HICMHLEF_01096 3.7e-72 yliE T Putative diguanylate phosphodiesterase
HICMHLEF_01097 5.7e-162 nox C NADH oxidase
HICMHLEF_01099 5.9e-53 2.7.7.65 T diguanylate cyclase
HICMHLEF_01100 5.9e-77 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HICMHLEF_01101 1.1e-73
HICMHLEF_01102 3e-77 S Protein conserved in bacteria
HICMHLEF_01103 1.1e-47 ydaM M Glycosyl transferase family group 2
HICMHLEF_01104 2.2e-127 ydaM M Glycosyl transferase family group 2
HICMHLEF_01105 5.3e-202 ydaN S Bacterial cellulose synthase subunit
HICMHLEF_01106 3.5e-80 2.7.7.65 T diguanylate cyclase activity
HICMHLEF_01107 5.7e-84 yetL K helix_turn_helix multiple antibiotic resistance protein
HICMHLEF_01108 7.1e-62 P Rhodanese-like domain
HICMHLEF_01109 2e-227 bdhA C Iron-containing alcohol dehydrogenase
HICMHLEF_01110 3.7e-190 I carboxylic ester hydrolase activity
HICMHLEF_01111 9e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HICMHLEF_01112 2.1e-76 marR K Winged helix DNA-binding domain
HICMHLEF_01113 1.8e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HICMHLEF_01114 4.5e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HICMHLEF_01115 8.1e-129 fabK 1.3.1.9 S Nitronate monooxygenase
HICMHLEF_01116 2.3e-28 fabK 1.3.1.9 S Nitronate monooxygenase
HICMHLEF_01117 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HICMHLEF_01118 2e-118 IQ reductase
HICMHLEF_01119 2e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HICMHLEF_01120 1.3e-16 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HICMHLEF_01121 1.2e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HICMHLEF_01122 3.6e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HICMHLEF_01123 5.3e-150 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HICMHLEF_01124 6.9e-99 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HICMHLEF_01125 9.8e-25 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HICMHLEF_01126 6.5e-234 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HICMHLEF_01127 7.8e-160 azoB GM NmrA-like family
HICMHLEF_01129 3.6e-298 scrB 3.2.1.26 GH32 G invertase
HICMHLEF_01130 1.5e-175 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HICMHLEF_01131 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HICMHLEF_01132 1.9e-193 scrA 2.7.1.211 G phosphotransferase system
HICMHLEF_01133 1.1e-136 scrA 2.7.1.211 G phosphotransferase system
HICMHLEF_01134 0.0 pip V domain protein
HICMHLEF_01135 3.9e-99 ykiI
HICMHLEF_01136 1.3e-79 ykiI
HICMHLEF_01137 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HICMHLEF_01138 1.5e-215 hsdM 2.1.1.72 V type I restriction-modification system
HICMHLEF_01139 9.4e-71 3.1.21.3 V Type I restriction modification DNA specificity domain protein
HICMHLEF_01140 2e-166 L Belongs to the 'phage' integrase family
HICMHLEF_01141 6.4e-25 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HICMHLEF_01142 1.7e-36 3.1.21.3 V Type I restriction modification DNA specificity domain
HICMHLEF_01143 1.3e-116
HICMHLEF_01144 4.4e-88 F Permease for cytosine/purines, uracil, thiamine, allantoin
HICMHLEF_01145 2.8e-114 F Permease for cytosine/purines, uracil, thiamine, allantoin
HICMHLEF_01146 2.1e-117 S Protein of unknown function (DUF917)
HICMHLEF_01147 5.2e-78 S Protein of unknown function (DUF917)
HICMHLEF_01148 1.2e-288 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
HICMHLEF_01149 4.6e-139 cad S FMN_bind
HICMHLEF_01150 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HICMHLEF_01151 2.3e-17 ndh 1.6.99.3 C NADH dehydrogenase
HICMHLEF_01152 1.7e-81 ynhH S NusG domain II
HICMHLEF_01153 5.2e-99 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HICMHLEF_01154 1e-179 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HICMHLEF_01155 2.7e-80
HICMHLEF_01156 1.6e-63 T Calcineurin-like phosphoesterase superfamily domain
HICMHLEF_01158 2.3e-96
HICMHLEF_01159 2.6e-158
HICMHLEF_01160 2.7e-152 V ATPases associated with a variety of cellular activities
HICMHLEF_01161 7.1e-215
HICMHLEF_01162 5.8e-192
HICMHLEF_01163 1.5e-35 1.5.1.40 S Rossmann-like domain
HICMHLEF_01164 5.7e-72 1.5.1.40 S Rossmann-like domain
HICMHLEF_01165 6.1e-191 XK27_00915 C Luciferase-like monooxygenase
HICMHLEF_01166 1.2e-97 yacP S YacP-like NYN domain
HICMHLEF_01167 7e-144 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HICMHLEF_01168 6.9e-54 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HICMHLEF_01169 4.7e-257 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HICMHLEF_01170 3.3e-245 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HICMHLEF_01171 8.6e-99
HICMHLEF_01173 3.3e-259 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HICMHLEF_01174 1.3e-34 yhfC S Putative membrane peptidase family (DUF2324)
HICMHLEF_01175 1e-19 yhfC S Putative membrane peptidase family (DUF2324)
HICMHLEF_01176 2.2e-59 yhfC S Putative membrane peptidase family (DUF2324)
HICMHLEF_01177 9.4e-128 S Membrane
HICMHLEF_01178 7.5e-24 S Membrane
HICMHLEF_01179 2.8e-61 K helix_turn_helix gluconate operon transcriptional repressor
HICMHLEF_01180 2.9e-293 V ABC transporter transmembrane region
HICMHLEF_01181 4.4e-223 inlJ M MucBP domain
HICMHLEF_01182 2e-36 S ABC-2 family transporter protein
HICMHLEF_01183 1.4e-09 S ABC-2 family transporter protein
HICMHLEF_01184 3.1e-95 V ABC transporter, ATP-binding protein
HICMHLEF_01185 1.4e-108 K sequence-specific DNA binding
HICMHLEF_01186 8.3e-31 yacL S domain protein
HICMHLEF_01187 3.6e-127 yacL S domain protein
HICMHLEF_01188 9.7e-17 yacL S domain protein
HICMHLEF_01189 9.3e-46 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HICMHLEF_01190 5.3e-198 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HICMHLEF_01191 1.9e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
HICMHLEF_01192 4.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HICMHLEF_01193 2.7e-257 pepC 3.4.22.40 E aminopeptidase
HICMHLEF_01195 3e-245 pepC 3.4.22.40 E Peptidase C1-like family
HICMHLEF_01196 3e-193
HICMHLEF_01197 1.9e-209 S ABC-2 family transporter protein
HICMHLEF_01198 4.3e-166 V ATPases associated with a variety of cellular activities
HICMHLEF_01199 7.7e-92 kup P Transport of potassium into the cell
HICMHLEF_01200 4.1e-212 kup P Transport of potassium into the cell
HICMHLEF_01201 1.4e-62 kup P Transport of potassium into the cell
HICMHLEF_01202 1.4e-192 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
HICMHLEF_01203 2.2e-285 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
HICMHLEF_01204 1.8e-92 ccpN K Domain in cystathionine beta-synthase and other proteins.
HICMHLEF_01205 3.3e-49 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HICMHLEF_01206 2.5e-26 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HICMHLEF_01207 1.4e-151 ltrA S Bacterial low temperature requirement A protein (LtrA)
HICMHLEF_01208 7.2e-46
HICMHLEF_01209 3.6e-194 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HICMHLEF_01210 8.8e-09 yhjA S CsbD-like
HICMHLEF_01211 1.5e-119 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HICMHLEF_01212 5.2e-14 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HICMHLEF_01213 6.7e-80 EGP Major facilitator Superfamily
HICMHLEF_01214 3.6e-81 EGP Major facilitator Superfamily
HICMHLEF_01215 8.5e-115 udp 2.4.2.3, 3.2.2.4 F Phosphorylase superfamily
HICMHLEF_01216 7.3e-172 EGP Major facilitator Superfamily
HICMHLEF_01217 1.6e-68 KT Purine catabolism regulatory protein-like family
HICMHLEF_01218 4.5e-11 KT Purine catabolism regulatory protein-like family
HICMHLEF_01219 5.4e-08
HICMHLEF_01220 2.5e-32
HICMHLEF_01221 5e-18
HICMHLEF_01222 3.5e-211 pimH EGP Major facilitator Superfamily
HICMHLEF_01223 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HICMHLEF_01224 4e-23 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HICMHLEF_01225 6.1e-112 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HICMHLEF_01227 8.7e-93
HICMHLEF_01229 7.3e-27 bacI V MacB-like periplasmic core domain
HICMHLEF_01231 3.1e-55 macB V ABC transporter, ATP-binding protein
HICMHLEF_01234 3.2e-128 3.4.22.70 M Sortase family
HICMHLEF_01235 8.4e-290 M Cna protein B-type domain
HICMHLEF_01236 5.1e-259 M domain protein
HICMHLEF_01237 0.0 M domain protein
HICMHLEF_01238 3.3e-103
HICMHLEF_01239 4.3e-225 N Uncharacterized conserved protein (DUF2075)
HICMHLEF_01240 1.8e-206 MA20_36090 S Protein of unknown function (DUF2974)
HICMHLEF_01241 4.1e-97 K Helix-turn-helix XRE-family like proteins
HICMHLEF_01242 1.4e-56 K Transcriptional regulator PadR-like family
HICMHLEF_01243 7.1e-136
HICMHLEF_01244 6.6e-134
HICMHLEF_01245 9e-44 S Enterocin A Immunity
HICMHLEF_01246 2.7e-186 tas C Aldo/keto reductase family
HICMHLEF_01247 2.5e-253 yjjP S Putative threonine/serine exporter
HICMHLEF_01248 8.5e-59
HICMHLEF_01249 8.3e-187 mesE M Transport protein ComB
HICMHLEF_01250 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HICMHLEF_01252 1.6e-67 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HICMHLEF_01253 8.1e-120 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HICMHLEF_01254 7.3e-133 plnD K LytTr DNA-binding domain
HICMHLEF_01257 1.9e-44 spiA S Enterocin A Immunity
HICMHLEF_01258 5.8e-21
HICMHLEF_01263 4.4e-133 S CAAX protease self-immunity
HICMHLEF_01264 9.3e-69 K Transcriptional regulator
HICMHLEF_01265 6.4e-252 EGP Major Facilitator Superfamily
HICMHLEF_01266 2.4e-53
HICMHLEF_01267 1.2e-52 S Enterocin A Immunity
HICMHLEF_01268 1.7e-179 S Aldo keto reductase
HICMHLEF_01269 7.1e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HICMHLEF_01270 4.5e-216 yqiG C Oxidoreductase
HICMHLEF_01272 9.5e-253 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HICMHLEF_01273 2.1e-133
HICMHLEF_01274 1.4e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HICMHLEF_01275 1.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HICMHLEF_01276 6.3e-145 tatD L hydrolase, TatD family
HICMHLEF_01277 2.6e-62 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HICMHLEF_01278 9.5e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
HICMHLEF_01279 6.9e-172 yqhA G Aldose 1-epimerase
HICMHLEF_01280 9.1e-79 T LytTr DNA-binding domain
HICMHLEF_01281 4.5e-166 2.7.13.3 T GHKL domain
HICMHLEF_01282 0.0 V ABC transporter
HICMHLEF_01283 1.8e-120 V ABC transporter
HICMHLEF_01284 8.2e-104 V ABC transporter
HICMHLEF_01285 3.2e-74 V ABC transporter
HICMHLEF_01286 4.1e-30 K Transcriptional
HICMHLEF_01287 2.2e-65
HICMHLEF_01288 1.2e-157 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HICMHLEF_01289 4e-217 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HICMHLEF_01290 1e-171 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HICMHLEF_01291 1.1e-150 yunF F Protein of unknown function DUF72
HICMHLEF_01292 2.3e-54 3.6.1.55 F NUDIX domain
HICMHLEF_01293 7.8e-28 3.6.1.55 F NUDIX domain
HICMHLEF_01295 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HICMHLEF_01296 5.3e-107 yiiE S Protein of unknown function (DUF1211)
HICMHLEF_01297 2.2e-128 cobB K Sir2 family
HICMHLEF_01298 1.2e-07
HICMHLEF_01299 5.7e-169
HICMHLEF_01300 1.9e-97 yxkA S Phosphatidylethanolamine-binding protein
HICMHLEF_01302 4.2e-162 ypuA S Protein of unknown function (DUF1002)
HICMHLEF_01303 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HICMHLEF_01304 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HICMHLEF_01305 2.5e-253 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HICMHLEF_01306 1.9e-172 S Aldo keto reductase
HICMHLEF_01307 9.3e-155 bioC 2.1.1.187, 2.1.1.197 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HICMHLEF_01308 1.7e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HICMHLEF_01309 2.5e-59 dinF V MatE
HICMHLEF_01310 4.2e-170 dinF V MatE
HICMHLEF_01311 5.5e-47 S TPM domain
HICMHLEF_01312 6.2e-46 S TPM domain
HICMHLEF_01313 3e-102 lemA S LemA family
HICMHLEF_01314 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HICMHLEF_01315 1.7e-10 EGP Major Facilitator Superfamily
HICMHLEF_01316 1.1e-53 EGP Major Facilitator Superfamily
HICMHLEF_01317 2.3e-251 gshR 1.8.1.7 C Glutathione reductase
HICMHLEF_01318 1.7e-176 proV E ABC transporter, ATP-binding protein
HICMHLEF_01319 3.8e-24 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HICMHLEF_01320 1.6e-56 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HICMHLEF_01321 1.6e-167 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HICMHLEF_01322 1.5e-144 helD 3.6.4.12 L DNA helicase
HICMHLEF_01323 2.6e-245 helD 3.6.4.12 L DNA helicase
HICMHLEF_01324 1.5e-147 rlrG K Transcriptional regulator
HICMHLEF_01325 1.1e-175 shetA P Voltage-dependent anion channel
HICMHLEF_01326 1.5e-135 nodJ V ABC-2 type transporter
HICMHLEF_01327 1.1e-89 nodI V ABC transporter
HICMHLEF_01328 1.7e-23 nodI V ABC transporter
HICMHLEF_01329 1.2e-129 ydfF K Transcriptional
HICMHLEF_01330 1.2e-109 S CAAX protease self-immunity
HICMHLEF_01332 2.9e-157 V ABC transporter transmembrane region
HICMHLEF_01333 4.9e-107 V ABC transporter transmembrane region
HICMHLEF_01334 6.7e-108 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HICMHLEF_01335 7.2e-71 K MarR family
HICMHLEF_01336 0.0 uvrA3 L excinuclease ABC
HICMHLEF_01337 1.4e-192 yghZ C Aldo keto reductase family protein
HICMHLEF_01338 2.4e-142 S hydrolase
HICMHLEF_01339 6.3e-38
HICMHLEF_01340 2.4e-12
HICMHLEF_01341 4.8e-12
HICMHLEF_01342 3.6e-115 yoaK S Protein of unknown function (DUF1275)
HICMHLEF_01343 2.4e-127 yjhF G Phosphoglycerate mutase family
HICMHLEF_01344 8.1e-151 yitU 3.1.3.104 S hydrolase
HICMHLEF_01345 3.6e-90 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HICMHLEF_01346 6.5e-166 K LysR substrate binding domain
HICMHLEF_01347 1.2e-46 EK Aminotransferase, class I
HICMHLEF_01348 4.1e-127 EK Aminotransferase, class I
HICMHLEF_01349 1.6e-28 EK Aminotransferase, class I
HICMHLEF_01351 2e-40
HICMHLEF_01352 9.4e-58
HICMHLEF_01353 2.9e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HICMHLEF_01354 7.3e-116 ydfK S Protein of unknown function (DUF554)
HICMHLEF_01355 2.2e-87
HICMHLEF_01356 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_01357 1.3e-168 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
HICMHLEF_01358 2.2e-129 rpl K Helix-turn-helix domain, rpiR family
HICMHLEF_01359 2.8e-298 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HICMHLEF_01360 5.7e-288 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HICMHLEF_01361 3.2e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HICMHLEF_01362 5.6e-245 P Sodium:sulfate symporter transmembrane region
HICMHLEF_01363 5.8e-158 K LysR substrate binding domain
HICMHLEF_01364 1.3e-75
HICMHLEF_01365 9e-72 K Transcriptional regulator
HICMHLEF_01366 7.1e-27 ypiB EGP Major facilitator Superfamily
HICMHLEF_01367 1.6e-155 ypiB EGP Major facilitator Superfamily
HICMHLEF_01368 3.2e-44 ypiB EGP Major facilitator Superfamily
HICMHLEF_01369 7.8e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HICMHLEF_01371 4.3e-241 pts36C G PTS system sugar-specific permease component
HICMHLEF_01372 1.1e-50 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_01373 3e-68 pts36A 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_01375 9.1e-106 K DeoR C terminal sensor domain
HICMHLEF_01377 3.2e-135 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HICMHLEF_01379 1.6e-73 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HICMHLEF_01380 2.2e-121 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HICMHLEF_01381 3.8e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HICMHLEF_01382 4.5e-285 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HICMHLEF_01383 8.8e-227 iolF EGP Major facilitator Superfamily
HICMHLEF_01384 4.1e-192 rhaR K helix_turn_helix, arabinose operon control protein
HICMHLEF_01385 4.2e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HICMHLEF_01386 1.4e-65 S Protein of unknown function (DUF1093)
HICMHLEF_01387 3.8e-82
HICMHLEF_01388 1.3e-25
HICMHLEF_01389 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HICMHLEF_01390 6.6e-47 V ATPase activity
HICMHLEF_01392 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HICMHLEF_01393 1.8e-303 oppA E ABC transporter, substratebinding protein
HICMHLEF_01394 1e-63
HICMHLEF_01395 2.7e-69
HICMHLEF_01396 2e-116
HICMHLEF_01397 2.5e-118 V ATPases associated with a variety of cellular activities
HICMHLEF_01398 1.6e-74
HICMHLEF_01399 2.5e-80 S NUDIX domain
HICMHLEF_01400 3e-212 S nuclear-transcribed mRNA catabolic process, no-go decay
HICMHLEF_01401 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
HICMHLEF_01402 9.4e-261 nox 1.6.3.4 C NADH oxidase
HICMHLEF_01403 1.7e-116
HICMHLEF_01404 5.1e-210 S TPM domain
HICMHLEF_01405 4e-129 yxaA S Sulfite exporter TauE/SafE
HICMHLEF_01406 1e-55 ywjH S Protein of unknown function (DUF1634)
HICMHLEF_01408 1.1e-64
HICMHLEF_01409 2.1e-51
HICMHLEF_01410 4.7e-77 fld C Flavodoxin
HICMHLEF_01411 3.4e-36
HICMHLEF_01412 1.1e-170 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HICMHLEF_01413 9.1e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
HICMHLEF_01414 6.4e-38 S Transglycosylase associated protein
HICMHLEF_01415 2.5e-25 S Protein conserved in bacteria
HICMHLEF_01416 1.8e-54 S Protein conserved in bacteria
HICMHLEF_01417 2.5e-29
HICMHLEF_01418 5.1e-61 asp23 S Asp23 family, cell envelope-related function
HICMHLEF_01419 1e-45 asp2 S Asp23 family, cell envelope-related function
HICMHLEF_01421 4.7e-128 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HICMHLEF_01422 6e-115 S Protein of unknown function (DUF969)
HICMHLEF_01423 5.2e-146 S Protein of unknown function (DUF979)
HICMHLEF_01424 8.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HICMHLEF_01425 5.7e-104 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HICMHLEF_01427 1e-127 cobQ S glutamine amidotransferase
HICMHLEF_01428 3.7e-66
HICMHLEF_01429 2.8e-134 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HICMHLEF_01430 2.4e-142 noc K Belongs to the ParB family
HICMHLEF_01431 7.4e-138 soj D Sporulation initiation inhibitor
HICMHLEF_01432 2e-155 spo0J K Belongs to the ParB family
HICMHLEF_01433 1.3e-30 yyzM S Bacterial protein of unknown function (DUF951)
HICMHLEF_01434 1.5e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HICMHLEF_01435 7.3e-141 XK27_01040 S Protein of unknown function (DUF1129)
HICMHLEF_01436 5.1e-268 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HICMHLEF_01437 1.7e-117
HICMHLEF_01438 2.5e-121 K response regulator
HICMHLEF_01439 1.2e-219 hpk31 2.7.13.3 T Histidine kinase
HICMHLEF_01440 5.3e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HICMHLEF_01441 1.2e-85 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HICMHLEF_01442 1e-295 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HICMHLEF_01443 2.7e-140 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HICMHLEF_01444 1.1e-163 yvgN C Aldo keto reductase
HICMHLEF_01445 1.3e-90 iolR K DeoR C terminal sensor domain
HICMHLEF_01446 4.1e-18 iolR K DeoR C terminal sensor domain
HICMHLEF_01447 1.9e-267 iolT EGP Major facilitator Superfamily
HICMHLEF_01448 6.1e-274 iolA 1.2.1.18, 1.2.1.27 C Belongs to the aldehyde dehydrogenase family
HICMHLEF_01449 6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HICMHLEF_01450 5.4e-178 iolC 2.7.1.92 H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HICMHLEF_01451 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HICMHLEF_01452 7.1e-192 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HICMHLEF_01453 1.8e-195 iolG2 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
HICMHLEF_01454 1.2e-174 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HICMHLEF_01455 6.2e-157 iolJ 4.1.2.13, 4.1.2.29 G Fructose-bisphosphate aldolase class-II
HICMHLEF_01456 7.5e-57 iolK S Tautomerase enzyme
HICMHLEF_01457 1.7e-157 iolI 5.3.99.11 G Xylose isomerase-like TIM barrel
HICMHLEF_01458 1.9e-169 iolH G Xylose isomerase-like TIM barrel
HICMHLEF_01459 5.6e-147 gntR K rpiR family
HICMHLEF_01460 1e-168 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HICMHLEF_01461 7.9e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HICMHLEF_01462 5e-206 gntP EG Gluconate
HICMHLEF_01463 1e-44
HICMHLEF_01464 2.9e-52 fhuC 3.6.3.35 P ABC transporter
HICMHLEF_01465 6.1e-61 fhuC 3.6.3.35 P ABC transporter
HICMHLEF_01466 3e-134 znuB U ABC 3 transport family
HICMHLEF_01467 2.6e-120 T Calcineurin-like phosphoesterase superfamily domain
HICMHLEF_01468 6.2e-32 T Calcineurin-like phosphoesterase superfamily domain
HICMHLEF_01469 9.7e-32 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HICMHLEF_01470 1.6e-30 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HICMHLEF_01471 9.9e-72 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HICMHLEF_01472 0.0 pepF E oligoendopeptidase F
HICMHLEF_01473 2e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HICMHLEF_01474 1.2e-242 brnQ U Component of the transport system for branched-chain amino acids
HICMHLEF_01475 4.5e-70 T Sh3 type 3 domain protein
HICMHLEF_01476 2.2e-134 glcR K DeoR C terminal sensor domain
HICMHLEF_01477 7.5e-146 M Glycosyltransferase like family 2
HICMHLEF_01478 1.8e-133 XK27_06755 S Protein of unknown function (DUF975)
HICMHLEF_01479 6.4e-52
HICMHLEF_01480 8.3e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HICMHLEF_01481 6e-97 draG O ADP-ribosylglycohydrolase
HICMHLEF_01482 3e-69 draG O ADP-ribosylglycohydrolase
HICMHLEF_01483 4.7e-293 S ABC transporter
HICMHLEF_01484 7.4e-48 ksgA 2.1.1.182, 2.1.1.197, 2.5.1.134 J rRNA (adenine-N6,N6-)-dimethyltransferase activity
HICMHLEF_01485 8e-45 S Acetyltransferase (GNAT) family
HICMHLEF_01487 1.2e-153 nisT V ABC transporter
HICMHLEF_01488 4.9e-33
HICMHLEF_01489 1.5e-23
HICMHLEF_01490 3.7e-82 S ABC-type cobalt transport system, permease component
HICMHLEF_01491 1.8e-51 P ABC transporter
HICMHLEF_01492 6.9e-137 P ABC transporter
HICMHLEF_01493 1.5e-33 P ABC transporter
HICMHLEF_01494 6.8e-42 P cobalt transport
HICMHLEF_01495 3.3e-59 P cobalt transport
HICMHLEF_01496 1.7e-125 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HICMHLEF_01497 4.1e-75 thiW S Thiamine-precursor transporter protein (ThiW)
HICMHLEF_01498 9.3e-78 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HICMHLEF_01499 6e-58 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HICMHLEF_01500 1.6e-101 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HICMHLEF_01501 3.2e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HICMHLEF_01502 2.2e-175 E Amino acid permease
HICMHLEF_01504 9.7e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HICMHLEF_01505 2.7e-43 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HICMHLEF_01506 2.6e-145 rbsA 3.6.3.17 G ABC transporter
HICMHLEF_01507 4.8e-114 rbsA 3.6.3.17 G ABC transporter
HICMHLEF_01508 1.2e-41 rbsC U Belongs to the binding-protein-dependent transport system permease family
HICMHLEF_01509 1.5e-107 rbsC U Belongs to the binding-protein-dependent transport system permease family
HICMHLEF_01510 4.3e-159 rbsB G Periplasmic binding protein domain
HICMHLEF_01511 6.2e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HICMHLEF_01512 1.8e-42 K DNA-binding helix-turn-helix protein
HICMHLEF_01519 4.8e-143 S Protein of unknown function (DUF2785)
HICMHLEF_01520 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
HICMHLEF_01521 5.5e-52
HICMHLEF_01522 7.1e-86 V AAA domain, putative AbiEii toxin, Type IV TA system
HICMHLEF_01524 2.9e-50
HICMHLEF_01525 1.9e-47
HICMHLEF_01526 2.3e-94
HICMHLEF_01527 1.3e-77 ydiC1 EGP Major facilitator Superfamily
HICMHLEF_01528 2.9e-90 ydiC1 EGP Major facilitator Superfamily
HICMHLEF_01529 3e-25 ydiC1 EGP Major facilitator Superfamily
HICMHLEF_01530 2.3e-67 K helix_turn_helix multiple antibiotic resistance protein
HICMHLEF_01531 3.9e-104
HICMHLEF_01532 1e-28
HICMHLEF_01533 9.8e-129 GKT transcriptional antiterminator
HICMHLEF_01534 1.4e-153 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT transcriptional antiterminator
HICMHLEF_01535 6e-46 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_01536 1.6e-195 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HICMHLEF_01537 6.3e-21
HICMHLEF_01538 1.5e-50 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HICMHLEF_01539 1.2e-68 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HICMHLEF_01540 3.8e-87 6.3.4.4 S Zeta toxin
HICMHLEF_01541 2.1e-155 rihB 3.2.2.1 F Nucleoside
HICMHLEF_01542 2.3e-33 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
HICMHLEF_01543 3e-69 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
HICMHLEF_01544 5.9e-88 dcuD C Tripartite ATP-independent periplasmic transporter, DctM component
HICMHLEF_01545 1.4e-44 K Acetyltransferase (GNAT) family
HICMHLEF_01546 8.3e-92 K helix_turn_helix gluconate operon transcriptional repressor
HICMHLEF_01547 6.9e-15 K helix_turn_helix gluconate operon transcriptional repressor
HICMHLEF_01548 1.1e-88 4.1.2.13 G DeoC/LacD family aldolase
HICMHLEF_01549 9.9e-39 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HICMHLEF_01550 1.1e-180 2.7.1.53 G Belongs to the FGGY kinase family
HICMHLEF_01551 8.8e-91 IQ KR domain
HICMHLEF_01552 2.5e-125 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HICMHLEF_01553 2e-156 gatC G COG3775 Phosphotransferase system, galactitol-specific IIC component
HICMHLEF_01554 3e-286 K Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_01555 6.4e-154 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HICMHLEF_01556 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphotransferase system
HICMHLEF_01557 5.4e-239 sorE E Alcohol dehydrogenase GroES-like domain
HICMHLEF_01558 3e-121 sorC K sugar-binding domain protein
HICMHLEF_01559 3.2e-29 IQ NAD dependent epimerase/dehydratase family
HICMHLEF_01560 2e-54 IQ NAD dependent epimerase/dehydratase family
HICMHLEF_01561 3.6e-62 sorF 2.7.1.191, 2.7.1.206 G PTS system fructose IIA component
HICMHLEF_01562 1.9e-78 sorB 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
HICMHLEF_01563 3.6e-130 sorA U PTS system sorbose-specific iic component
HICMHLEF_01564 2.1e-91 sorM G system, mannose fructose sorbose family IID component
HICMHLEF_01565 2.5e-44 sorM G system, mannose fructose sorbose family IID component
HICMHLEF_01566 3.4e-136 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HICMHLEF_01567 1.4e-238 P transporter
HICMHLEF_01568 9.8e-124 C FAD dependent oxidoreductase
HICMHLEF_01569 1e-12 C FAD dependent oxidoreductase
HICMHLEF_01570 4.9e-109 K Transcriptional regulator, LysR family
HICMHLEF_01571 1.1e-158 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
HICMHLEF_01572 2.7e-97 S UPF0397 protein
HICMHLEF_01573 0.0 3.6.3.24 P ATP-binding cassette cobalt transporter
HICMHLEF_01574 1.8e-145 cbiQ P cobalt transport
HICMHLEF_01575 1e-150 K Transcriptional regulator, LacI family
HICMHLEF_01576 5.1e-125 G Major Facilitator
HICMHLEF_01577 3.1e-108 G Major Facilitator
HICMHLEF_01578 2.7e-47 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HICMHLEF_01579 3e-235 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HICMHLEF_01580 2.4e-101 frdC 1.3.5.4 C HI0933-like protein
HICMHLEF_01581 1e-140 frdC 1.3.5.4 C HI0933-like protein
HICMHLEF_01582 6.3e-162 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HICMHLEF_01583 4.6e-55 yheA S Control of competence regulator ComK, YlbF/YmcA
HICMHLEF_01584 7e-308 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HICMHLEF_01585 2.1e-71 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HICMHLEF_01586 3.6e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HICMHLEF_01587 2e-74 argR K Regulates arginine biosynthesis genes
HICMHLEF_01588 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HICMHLEF_01590 1.7e-66
HICMHLEF_01591 1.6e-79 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HICMHLEF_01592 4.7e-88 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HICMHLEF_01593 9.4e-60 glpQ 3.1.4.46 C phosphodiesterase
HICMHLEF_01594 3.1e-227 glpQ 3.1.4.46 C phosphodiesterase
HICMHLEF_01595 5.1e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HICMHLEF_01596 1.5e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HICMHLEF_01597 4.6e-137 yhfI S Metallo-beta-lactamase superfamily
HICMHLEF_01598 7.6e-91 traP 1.14.99.57, 6.2.1.3 S Antibiotic biosynthesis monooxygenase
HICMHLEF_01599 0.0 V ABC transporter (permease)
HICMHLEF_01600 2.6e-138 bceA V ABC transporter
HICMHLEF_01601 9.2e-123 K response regulator
HICMHLEF_01602 1.3e-207 T PhoQ Sensor
HICMHLEF_01603 3.2e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HICMHLEF_01604 1.3e-263 copB 3.6.3.4 P P-type ATPase
HICMHLEF_01605 1.4e-96 copB 3.6.3.4 P P-type ATPase
HICMHLEF_01606 1.6e-76 copR K Copper transport repressor CopY TcrY
HICMHLEF_01607 1.3e-93 purD 6.3.4.13 F Belongs to the GARS family
HICMHLEF_01608 3.6e-92 purD 6.3.4.13 F Belongs to the GARS family
HICMHLEF_01609 1.7e-114 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HICMHLEF_01610 1.1e-148 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HICMHLEF_01611 7.8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HICMHLEF_01612 3.2e-127 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HICMHLEF_01613 6.9e-47 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HICMHLEF_01614 4e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HICMHLEF_01615 8.2e-182 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HICMHLEF_01616 9.2e-239 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HICMHLEF_01617 3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HICMHLEF_01618 6.4e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HICMHLEF_01619 2.3e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HICMHLEF_01620 2.4e-141 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HICMHLEF_01621 8.4e-53 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HICMHLEF_01622 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HICMHLEF_01623 1.6e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
HICMHLEF_01625 1.2e-253 iolT EGP Major facilitator Superfamily
HICMHLEF_01626 7.4e-12
HICMHLEF_01627 9.6e-264 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HICMHLEF_01628 8e-49 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HICMHLEF_01629 2.7e-39 ptsH G phosphocarrier protein HPR
HICMHLEF_01630 2e-28
HICMHLEF_01631 0.0 clpE O Belongs to the ClpA ClpB family
HICMHLEF_01632 4.3e-46 XK27_09445 S Domain of unknown function (DUF1827)
HICMHLEF_01633 7.9e-304 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HICMHLEF_01634 2.3e-243 hlyX S Transporter associated domain
HICMHLEF_01635 9.1e-204 yueF S AI-2E family transporter
HICMHLEF_01636 8.6e-75 S Acetyltransferase (GNAT) domain
HICMHLEF_01637 2.8e-96
HICMHLEF_01638 4e-104 ygaC J Belongs to the UPF0374 family
HICMHLEF_01639 6.5e-137 recX 2.4.1.337 GT4 S Regulatory protein RecX
HICMHLEF_01640 2.6e-291 frvR K Mga helix-turn-helix domain
HICMHLEF_01641 9.9e-58
HICMHLEF_01642 4e-251 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HICMHLEF_01643 1.1e-78 F Nucleoside 2-deoxyribosyltransferase
HICMHLEF_01644 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HICMHLEF_01646 1.5e-219 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HICMHLEF_01647 6.9e-210 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
HICMHLEF_01648 2.5e-68 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HICMHLEF_01649 1.3e-114 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HICMHLEF_01650 2e-46
HICMHLEF_01651 6.3e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HICMHLEF_01652 8e-36 V Restriction endonuclease
HICMHLEF_01653 4.8e-58 V Restriction endonuclease
HICMHLEF_01654 1.8e-158 5.1.3.3 G Aldose 1-epimerase
HICMHLEF_01655 4.4e-211 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HICMHLEF_01656 4.4e-101 S ECF transporter, substrate-specific component
HICMHLEF_01658 6.6e-81 yodP 2.3.1.264 K FR47-like protein
HICMHLEF_01659 1.3e-81 ydcK S Belongs to the SprT family
HICMHLEF_01660 6.2e-129 XK27_08845 S ABC transporter, ATP-binding protein
HICMHLEF_01661 5.2e-25 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HICMHLEF_01662 1.7e-79 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HICMHLEF_01663 4e-176 XK27_08835 S ABC transporter
HICMHLEF_01664 6.3e-71
HICMHLEF_01665 0.0 pacL 3.6.3.8 P P-type ATPase
HICMHLEF_01666 7.2e-20 pacL 3.6.3.8 P P-type ATPase
HICMHLEF_01667 9.6e-183 ykcC GT2 M Glycosyl transferase family 2
HICMHLEF_01668 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
HICMHLEF_01669 3.9e-57 S GtrA-like protein
HICMHLEF_01670 1.7e-09
HICMHLEF_01671 2.8e-08
HICMHLEF_01672 3.7e-91 K cheY-homologous receiver domain
HICMHLEF_01673 4.9e-149 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HICMHLEF_01674 3.7e-44 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HICMHLEF_01675 1.2e-67 yqkB S Belongs to the HesB IscA family
HICMHLEF_01676 1.9e-121 drgA C Nitroreductase family
HICMHLEF_01677 4.6e-66 lctO C IMP dehydrogenase / GMP reductase domain
HICMHLEF_01678 2.4e-124 lctO C IMP dehydrogenase / GMP reductase domain
HICMHLEF_01682 2.2e-07 rggD K Transcriptional regulator RggD
HICMHLEF_01686 1.4e-06 mutR K Helix-turn-helix
HICMHLEF_01688 1.4e-72 K sequence-specific DNA binding
HICMHLEF_01689 1.6e-82 K sequence-specific DNA binding
HICMHLEF_01690 3.1e-56 K Transcriptional regulator PadR-like family
HICMHLEF_01691 4e-42 ygbF S Sugar efflux transporter for intercellular exchange
HICMHLEF_01692 1.5e-31
HICMHLEF_01693 1.1e-184 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HICMHLEF_01694 3.4e-56
HICMHLEF_01695 3.4e-80
HICMHLEF_01696 5.1e-207 yubA S AI-2E family transporter
HICMHLEF_01697 7.4e-26
HICMHLEF_01698 3e-97 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HICMHLEF_01699 1.4e-75
HICMHLEF_01700 1.8e-19 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HICMHLEF_01701 9.7e-72 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HICMHLEF_01702 1.5e-104 ywrF S Flavin reductase like domain
HICMHLEF_01703 6.7e-96
HICMHLEF_01704 4e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HICMHLEF_01705 3.3e-61 yeaO S Protein of unknown function, DUF488
HICMHLEF_01706 1.2e-97 corA P CorA-like Mg2+ transporter protein
HICMHLEF_01707 9.9e-42 corA P CorA-like Mg2+ transporter protein
HICMHLEF_01708 4.7e-91 mleR K LysR family
HICMHLEF_01709 1.1e-42 mleR K LysR family
HICMHLEF_01710 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HICMHLEF_01711 1.1e-170 mleP S Sodium Bile acid symporter family
HICMHLEF_01712 5.9e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HICMHLEF_01713 3.1e-95
HICMHLEF_01714 7.6e-89 K sequence-specific DNA binding
HICMHLEF_01715 4.6e-65 K sequence-specific DNA binding
HICMHLEF_01716 1.8e-108 V ABC transporter transmembrane region
HICMHLEF_01717 1.2e-161 V ABC transporter transmembrane region
HICMHLEF_01718 0.0 pepF E Oligopeptidase F
HICMHLEF_01719 5e-78 ndk 2.7.4.6 F Belongs to the NDK family
HICMHLEF_01720 2.3e-41
HICMHLEF_01721 6.6e-134 yfgQ P E1-E2 ATPase
HICMHLEF_01722 3.6e-267 yfgQ P E1-E2 ATPase
HICMHLEF_01723 8.8e-178 3.4.11.5 I Releases the N-terminal proline from various substrates
HICMHLEF_01724 1.1e-54
HICMHLEF_01725 4.6e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HICMHLEF_01726 3.6e-197 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HICMHLEF_01727 1.6e-120 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
HICMHLEF_01728 1.5e-77 K Transcriptional regulator
HICMHLEF_01729 1.5e-84 D Alpha beta
HICMHLEF_01730 1.1e-77 D Alpha beta
HICMHLEF_01731 2.3e-76 nrdI F Belongs to the NrdI family
HICMHLEF_01732 2.9e-156 dkgB S reductase
HICMHLEF_01733 4e-120
HICMHLEF_01734 1.4e-87 S Alpha beta hydrolase
HICMHLEF_01735 4e-53 S Alpha beta hydrolase
HICMHLEF_01736 7.9e-85 yviA S Protein of unknown function (DUF421)
HICMHLEF_01737 3.5e-74 S Protein of unknown function (DUF3290)
HICMHLEF_01738 6.7e-220 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HICMHLEF_01739 1.6e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HICMHLEF_01740 3.2e-46 yjbF S SNARE associated Golgi protein
HICMHLEF_01741 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HICMHLEF_01742 8.1e-171 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HICMHLEF_01743 2.6e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HICMHLEF_01744 3.8e-220 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HICMHLEF_01745 2.7e-33 yajC U Preprotein translocase
HICMHLEF_01746 2.8e-266 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HICMHLEF_01747 5e-179 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HICMHLEF_01748 4.9e-30 sirR K Helix-turn-helix diphteria tox regulatory element
HICMHLEF_01749 5e-75 sirR K Helix-turn-helix diphteria tox regulatory element
HICMHLEF_01750 1.1e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HICMHLEF_01751 3.3e-237 rarA L recombination factor protein RarA
HICMHLEF_01752 0.0 6.3.2.2, 6.3.2.4 M Mur ligase middle domain protein
HICMHLEF_01753 3.9e-72 yueI S Protein of unknown function (DUF1694)
HICMHLEF_01754 4.9e-57 yktB S Belongs to the UPF0637 family
HICMHLEF_01755 4.2e-41 yktB S Belongs to the UPF0637 family
HICMHLEF_01756 2.2e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HICMHLEF_01757 1.8e-70 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HICMHLEF_01758 1.4e-70 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HICMHLEF_01759 3e-122 G Phosphoglycerate mutase family
HICMHLEF_01760 7.3e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HICMHLEF_01761 4.4e-95 IQ NAD dependent epimerase/dehydratase family
HICMHLEF_01762 4.7e-61 IQ NAD dependent epimerase/dehydratase family
HICMHLEF_01763 2.7e-137 pnuC H nicotinamide mononucleotide transporter
HICMHLEF_01764 2.6e-132 dck 2.7.1.74 F deoxynucleoside kinase
HICMHLEF_01765 1.7e-156 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HICMHLEF_01766 0.0 oppA E ABC transporter, substratebinding protein
HICMHLEF_01767 5.8e-52 T GHKL domain
HICMHLEF_01768 7.6e-87 T GHKL domain
HICMHLEF_01769 4e-119 T Transcriptional regulatory protein, C terminal
HICMHLEF_01770 1.9e-167 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
HICMHLEF_01771 8.2e-129 S ABC-2 family transporter protein
HICMHLEF_01772 9.4e-161 K Transcriptional regulator
HICMHLEF_01773 7.2e-79 yphH S Cupin domain
HICMHLEF_01774 4.2e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HICMHLEF_01776 2.2e-11 K Psort location Cytoplasmic, score
HICMHLEF_01777 2e-83 K Psort location Cytoplasmic, score
HICMHLEF_01778 1.5e-163 2.3.1.128 K Acetyltransferase (GNAT) domain
HICMHLEF_01779 1.7e-84 K Acetyltransferase (GNAT) domain
HICMHLEF_01780 1.4e-153 S Uncharacterised protein, DegV family COG1307
HICMHLEF_01781 3.7e-106
HICMHLEF_01782 4e-102 desR K helix_turn_helix, Lux Regulon
HICMHLEF_01783 3.3e-116 desK 2.7.13.3 T Histidine kinase
HICMHLEF_01784 1.9e-46 desK 2.7.13.3 T Histidine kinase
HICMHLEF_01785 1.6e-129 yvfS V ABC-2 type transporter
HICMHLEF_01786 4.4e-158 yvfR V ABC transporter
HICMHLEF_01787 5.6e-95
HICMHLEF_01788 6.4e-154
HICMHLEF_01789 9.9e-150
HICMHLEF_01790 2.2e-82 K Acetyltransferase (GNAT) domain
HICMHLEF_01791 0.0 yhgF K Tex-like protein N-terminal domain protein
HICMHLEF_01792 6.8e-27 puuD S peptidase C26
HICMHLEF_01793 4e-18 puuD S peptidase C26
HICMHLEF_01794 3.7e-66 puuD S peptidase C26
HICMHLEF_01795 6.4e-206 steT E Amino acid permease
HICMHLEF_01796 1.1e-133 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HICMHLEF_01797 2.5e-145 S Domain of unknown function (DUF1998)
HICMHLEF_01798 2.4e-84 KL Helicase conserved C-terminal domain
HICMHLEF_01799 3.8e-97 KL Helicase conserved C-terminal domain
HICMHLEF_01800 4e-22 KL Helicase conserved C-terminal domain
HICMHLEF_01803 2.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HICMHLEF_01804 1.5e-83 ytsP 1.8.4.14 T GAF domain-containing protein
HICMHLEF_01805 5.7e-29 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HICMHLEF_01806 8.1e-206 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HICMHLEF_01807 1.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
HICMHLEF_01808 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HICMHLEF_01809 1.5e-115 rex K CoA binding domain
HICMHLEF_01810 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HICMHLEF_01811 3.1e-195 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HICMHLEF_01812 1.3e-114 S Haloacid dehalogenase-like hydrolase
HICMHLEF_01813 2.7e-118 radC L DNA repair protein
HICMHLEF_01814 7.8e-180 mreB D cell shape determining protein MreB
HICMHLEF_01815 8.5e-151 mreC M Involved in formation and maintenance of cell shape
HICMHLEF_01816 4.7e-83 mreD M rod shape-determining protein MreD
HICMHLEF_01817 1.4e-113 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HICMHLEF_01818 2.8e-140 minD D Belongs to the ParA family
HICMHLEF_01819 4.7e-109 artQ P ABC transporter permease
HICMHLEF_01820 1.7e-111 glnQ 3.6.3.21 E ABC transporter
HICMHLEF_01821 4.3e-152 aatB ET ABC transporter substrate-binding protein
HICMHLEF_01822 5.6e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HICMHLEF_01823 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HICMHLEF_01824 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HICMHLEF_01825 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HICMHLEF_01826 5.9e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HICMHLEF_01827 2.1e-241 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HICMHLEF_01828 5.2e-81 yabR J RNA binding
HICMHLEF_01829 4.4e-65 divIC D cell cycle
HICMHLEF_01830 1.8e-38 yabO J S4 domain protein
HICMHLEF_01831 1.6e-280 yabM S Polysaccharide biosynthesis protein
HICMHLEF_01832 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HICMHLEF_01833 2.7e-16 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HICMHLEF_01834 2.1e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HICMHLEF_01835 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HICMHLEF_01836 2.5e-145 S Putative peptidoglycan binding domain
HICMHLEF_01837 5e-74 S Putative peptidoglycan binding domain
HICMHLEF_01838 2.9e-96 padR K Transcriptional regulator PadR-like family
HICMHLEF_01839 1.1e-160 XK27_06930 S ABC-2 family transporter protein
HICMHLEF_01840 1.3e-64 XK27_06930 S ABC-2 family transporter protein
HICMHLEF_01841 3.4e-114 1.6.5.2 S Flavodoxin-like fold
HICMHLEF_01842 5.1e-119 S (CBS) domain
HICMHLEF_01843 1.8e-130 yciB M ErfK YbiS YcfS YnhG
HICMHLEF_01844 1.4e-33 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HICMHLEF_01845 1.8e-159 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HICMHLEF_01846 9.9e-27 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HICMHLEF_01847 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
HICMHLEF_01848 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
HICMHLEF_01849 4.5e-86 S QueT transporter
HICMHLEF_01850 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
HICMHLEF_01851 2.4e-37
HICMHLEF_01852 1.6e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HICMHLEF_01853 1.7e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HICMHLEF_01854 4.5e-264 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HICMHLEF_01855 5.6e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HICMHLEF_01856 3.3e-146
HICMHLEF_01857 1.9e-123 S Tetratricopeptide repeat
HICMHLEF_01858 5.5e-29
HICMHLEF_01859 7.3e-30
HICMHLEF_01860 6.7e-72
HICMHLEF_01861 3.3e-42 rpmE2 J Ribosomal protein L31
HICMHLEF_01862 7.4e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HICMHLEF_01864 5.4e-254 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HICMHLEF_01865 5.9e-219 ndh 1.6.99.3 C NADH dehydrogenase
HICMHLEF_01868 7.9e-152 S Protein of unknown function (DUF1211)
HICMHLEF_01869 5.9e-62 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HICMHLEF_01870 3.5e-79 ywiB S Domain of unknown function (DUF1934)
HICMHLEF_01871 4.6e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HICMHLEF_01872 7.4e-266 ywfO S HD domain protein
HICMHLEF_01873 2.4e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
HICMHLEF_01874 2.5e-94 S DUF218 domain
HICMHLEF_01875 2.1e-61 S DUF218 domain
HICMHLEF_01876 1.8e-60 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HICMHLEF_01877 1.6e-73
HICMHLEF_01878 8.6e-51 nudA S ASCH
HICMHLEF_01879 1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HICMHLEF_01880 1.3e-185 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HICMHLEF_01881 1.1e-51 ysaA V RDD family
HICMHLEF_01882 9.2e-139 ysaA V RDD family
HICMHLEF_01883 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HICMHLEF_01884 6.5e-119 ybbL S ABC transporter, ATP-binding protein
HICMHLEF_01885 3.3e-122 ybbM S Uncharacterised protein family (UPF0014)
HICMHLEF_01886 6.7e-159 czcD P cation diffusion facilitator family transporter
HICMHLEF_01887 5.8e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HICMHLEF_01888 1.1e-37 veg S Biofilm formation stimulator VEG
HICMHLEF_01889 7.9e-224 ywhK S Membrane
HICMHLEF_01891 2e-121 V ABC transporter transmembrane region
HICMHLEF_01892 1.7e-123 V ABC transporter transmembrane region
HICMHLEF_01893 1.5e-146 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HICMHLEF_01894 2.2e-176 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HICMHLEF_01895 1.6e-35 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HICMHLEF_01896 3.7e-35 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HICMHLEF_01897 5.8e-263 glnA 6.3.1.2 E glutamine synthetase
HICMHLEF_01898 1e-60 glnR K Transcriptional regulator
HICMHLEF_01899 3.3e-231 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HICMHLEF_01900 4.1e-130 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HICMHLEF_01901 6.5e-240 ynbB 4.4.1.1 P aluminum resistance
HICMHLEF_01902 1.5e-86 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HICMHLEF_01903 9.8e-25 WQ51_02665 S Protein of unknown function (DUF3042)
HICMHLEF_01904 3.7e-72 yqhL P Rhodanese-like protein
HICMHLEF_01905 2e-177 glk 2.7.1.2 G Glucokinase
HICMHLEF_01906 1.1e-40 yqgQ S Bacterial protein of unknown function (DUF910)
HICMHLEF_01907 9.6e-121 gluP 3.4.21.105 S Peptidase, S54 family
HICMHLEF_01908 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HICMHLEF_01909 2.1e-241 S Bacterial membrane protein YfhO
HICMHLEF_01910 6.2e-246 S Bacterial membrane protein YfhO
HICMHLEF_01911 4.4e-29 yneR S Belongs to the HesB IscA family
HICMHLEF_01912 6e-42 vraR K helix_turn_helix, Lux Regulon
HICMHLEF_01913 4.2e-60 vraR K helix_turn_helix, Lux Regulon
HICMHLEF_01914 8.3e-177 vraS 2.7.13.3 T Histidine kinase
HICMHLEF_01915 8.9e-122 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HICMHLEF_01917 9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HICMHLEF_01918 6.9e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HICMHLEF_01919 1.5e-206 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HICMHLEF_01920 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HICMHLEF_01921 1.9e-54 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HICMHLEF_01922 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HICMHLEF_01923 8.3e-67 yodB K Transcriptional regulator, HxlR family
HICMHLEF_01924 5.6e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HICMHLEF_01925 1.1e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HICMHLEF_01926 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HICMHLEF_01927 4.5e-180 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HICMHLEF_01928 2e-286 arlS 2.7.13.3 T Histidine kinase
HICMHLEF_01929 5.7e-118 K response regulator
HICMHLEF_01930 6.9e-231 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HICMHLEF_01931 7.7e-14 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HICMHLEF_01932 3.6e-85 yceD S Uncharacterized ACR, COG1399
HICMHLEF_01933 1.9e-184 ylbM S Belongs to the UPF0348 family
HICMHLEF_01934 1.7e-139 yqeM Q Methyltransferase
HICMHLEF_01935 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HICMHLEF_01936 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HICMHLEF_01937 9.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HICMHLEF_01938 1.2e-46 yhbY J RNA-binding protein
HICMHLEF_01939 3.4e-216 yqeH S Ribosome biogenesis GTPase YqeH
HICMHLEF_01940 1.6e-94 yqeG S HAD phosphatase, family IIIA
HICMHLEF_01941 2e-166 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HICMHLEF_01942 1.2e-190 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HICMHLEF_01943 1.8e-121 mhqD S Dienelactone hydrolase family
HICMHLEF_01944 8.6e-111 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
HICMHLEF_01945 1.8e-53 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
HICMHLEF_01946 1e-99 yvdD 3.2.2.10 S Belongs to the LOG family
HICMHLEF_01947 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HICMHLEF_01948 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HICMHLEF_01949 8.9e-78 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HICMHLEF_01950 5.7e-193 spoVK O ATPase family associated with various cellular activities (AAA)
HICMHLEF_01951 3.5e-36 spoVK O ATPase family associated with various cellular activities (AAA)
HICMHLEF_01953 4.2e-37 yfjR K WYL domain
HICMHLEF_01954 9.3e-59 S SseB protein N-terminal domain
HICMHLEF_01955 2.6e-22 S SseB protein N-terminal domain
HICMHLEF_01956 5.5e-65
HICMHLEF_01957 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HICMHLEF_01958 4.2e-128 dnaI L Primosomal protein DnaI
HICMHLEF_01959 3.4e-50 dnaB L replication initiation and membrane attachment
HICMHLEF_01960 9.5e-65 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HICMHLEF_01961 7.2e-43 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HICMHLEF_01962 8e-47 S Repeat protein
HICMHLEF_01963 3.6e-21 S Repeat protein
HICMHLEF_01964 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HICMHLEF_01965 1.3e-134 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HICMHLEF_01966 9.1e-226 els S Sterol carrier protein domain
HICMHLEF_01967 6.5e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HICMHLEF_01968 8.2e-67 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HICMHLEF_01969 1.9e-229 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HICMHLEF_01971 1.7e-73
HICMHLEF_01972 1.9e-25
HICMHLEF_01973 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HICMHLEF_01974 1.3e-109 S E1-E2 ATPase
HICMHLEF_01975 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HICMHLEF_01976 3.1e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HICMHLEF_01977 4.1e-109 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HICMHLEF_01978 2.3e-122 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HICMHLEF_01979 3.6e-112 lpdA 1.8.1.4 C Dehydrogenase
HICMHLEF_01980 1.2e-129 lpdA 1.8.1.4 C Dehydrogenase
HICMHLEF_01981 4.3e-93 1.1.1.27 C L-malate dehydrogenase activity
HICMHLEF_01982 1.8e-51 1.1.1.27 C L-malate dehydrogenase activity
HICMHLEF_01983 1.4e-46 yktA S Belongs to the UPF0223 family
HICMHLEF_01984 2.3e-139 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HICMHLEF_01985 0.0 typA T GTP-binding protein TypA
HICMHLEF_01986 8.5e-210 ftsW D Belongs to the SEDS family
HICMHLEF_01987 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HICMHLEF_01988 3.8e-57 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HICMHLEF_01989 1.7e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HICMHLEF_01990 2.8e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HICMHLEF_01991 2.8e-80 ylbL T Belongs to the peptidase S16 family
HICMHLEF_01992 9.6e-95 ylbL T Belongs to the peptidase S16 family
HICMHLEF_01993 2.6e-107 comEA L Competence protein ComEA
HICMHLEF_01994 2e-112 comEC S Competence protein ComEC
HICMHLEF_01995 1.3e-301 comEC S Competence protein ComEC
HICMHLEF_01996 2e-194 holA 2.7.7.7 L DNA polymerase III delta subunit
HICMHLEF_01997 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
HICMHLEF_01998 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HICMHLEF_01999 4.9e-115
HICMHLEF_02000 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HICMHLEF_02001 4.7e-127 S Tetratricopeptide repeat
HICMHLEF_02002 2.5e-22 S Tetratricopeptide repeat
HICMHLEF_02003 1.2e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HICMHLEF_02004 2.2e-82 M Protein of unknown function (DUF3737)
HICMHLEF_02005 7.1e-101 cobB K Sir2 family
HICMHLEF_02006 4.9e-18 cobB K Sir2 family
HICMHLEF_02007 1.7e-63 pcaC 4.1.1.44 S Carboxymuconolactone decarboxylase family
HICMHLEF_02008 3.5e-58 rmeD K helix_turn_helix, mercury resistance
HICMHLEF_02009 0.0 yknV V ABC transporter
HICMHLEF_02010 3.2e-197 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HICMHLEF_02011 1.5e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HICMHLEF_02012 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HICMHLEF_02013 1e-47 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HICMHLEF_02014 2.3e-20
HICMHLEF_02015 1.5e-259 glnPH2 P ABC transporter permease
HICMHLEF_02016 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HICMHLEF_02017 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HICMHLEF_02018 1.5e-247 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HICMHLEF_02019 8e-90 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HICMHLEF_02020 2.7e-155 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HICMHLEF_02021 7.7e-132 fruR K DeoR C terminal sensor domain
HICMHLEF_02022 1.9e-234 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HICMHLEF_02023 4.7e-35 oatA I Acyltransferase
HICMHLEF_02024 1.8e-207 oatA I Acyltransferase
HICMHLEF_02025 3.9e-107 L Transposase and inactivated derivatives, IS30 family
HICMHLEF_02026 1.6e-37 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HICMHLEF_02027 3.1e-37
HICMHLEF_02028 3.1e-60 S Protein of unknown function (DUF1093)
HICMHLEF_02029 2.3e-26
HICMHLEF_02030 3.2e-61
HICMHLEF_02033 3.6e-46 D Anion-transporting ATPase
HICMHLEF_02034 1.9e-12 yeeA V Type II restriction enzyme, methylase subunits
HICMHLEF_02035 1.1e-244 yeeA V Type II restriction enzyme, methylase subunits
HICMHLEF_02036 6.6e-40 K Helix-turn-helix domain
HICMHLEF_02037 1.1e-38 S Phage derived protein Gp49-like (DUF891)
HICMHLEF_02038 5.4e-15 K sequence-specific DNA binding
HICMHLEF_02040 1.1e-68 K Psort location Cytoplasmic, score 8.87
HICMHLEF_02041 1e-71 L Belongs to the 'phage' integrase family
HICMHLEF_02043 9.2e-112 1.6.5.2 S Flavodoxin-like fold
HICMHLEF_02044 3.8e-91 K Bacterial regulatory proteins, tetR family
HICMHLEF_02045 1.9e-186 mocA S Oxidoreductase
HICMHLEF_02046 5.7e-273 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HICMHLEF_02047 5.1e-295 2.4.1.52 GT4 M Glycosyl transferases group 1
HICMHLEF_02049 4.8e-277 2.4.1.9, 3.4.24.40 GH68 S peptidase inhibitor activity
HICMHLEF_02050 1.1e-14 2.4.1.9, 3.4.24.40 GH68 S peptidase inhibitor activity
HICMHLEF_02052 3.6e-296
HICMHLEF_02053 2.5e-58
HICMHLEF_02054 1e-124
HICMHLEF_02055 3.3e-186
HICMHLEF_02056 5.3e-147 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
HICMHLEF_02057 1.2e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HICMHLEF_02058 3.7e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HICMHLEF_02059 7.1e-44 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HICMHLEF_02060 4.6e-42 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HICMHLEF_02061 2.1e-219 recJ L Single-stranded-DNA-specific exonuclease RecJ
HICMHLEF_02062 2.5e-182 recJ L Single-stranded-DNA-specific exonuclease RecJ
HICMHLEF_02063 7.1e-62
HICMHLEF_02064 9.4e-83 6.3.3.2 S ASCH
HICMHLEF_02065 5.9e-32
HICMHLEF_02066 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HICMHLEF_02067 2.6e-187 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HICMHLEF_02068 1.1e-89 dnaK O Heat shock 70 kDa protein
HICMHLEF_02069 2.7e-100 dnaK O Heat shock 70 kDa protein
HICMHLEF_02070 3.9e-44 dnaK O Heat shock 70 kDa protein
HICMHLEF_02071 3.4e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HICMHLEF_02073 3e-56 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HICMHLEF_02074 1.1e-124 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HICMHLEF_02075 9.8e-79 hemN H Involved in the biosynthesis of porphyrin-containing compound
HICMHLEF_02076 6.9e-136 hemN H Involved in the biosynthesis of porphyrin-containing compound
HICMHLEF_02077 7.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HICMHLEF_02078 2.2e-143 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HICMHLEF_02079 4.8e-09 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HICMHLEF_02080 6.7e-119 terC P membrane
HICMHLEF_02081 5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HICMHLEF_02082 4.1e-44 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HICMHLEF_02083 6.4e-10 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HICMHLEF_02084 9.1e-300 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HICMHLEF_02085 4.4e-57 S Family of unknown function (DUF5322)
HICMHLEF_02086 1.1e-68 rnhA 3.1.26.4 L Ribonuclease HI
HICMHLEF_02087 1.5e-109 XK27_02070 S Nitroreductase family
HICMHLEF_02088 1.8e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HICMHLEF_02089 9.7e-55
HICMHLEF_02091 1.6e-271 K Mga helix-turn-helix domain
HICMHLEF_02092 4.5e-38 nrdH O Glutaredoxin
HICMHLEF_02093 9.4e-158 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HICMHLEF_02094 3.6e-194 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HICMHLEF_02095 9.2e-93 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HICMHLEF_02096 1.5e-79 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HICMHLEF_02098 4.1e-164 K Transcriptional regulator
HICMHLEF_02099 5.2e-74 pepO 3.4.24.71 O Peptidase family M13
HICMHLEF_02100 4.4e-189 pepO 3.4.24.71 O Peptidase family M13
HICMHLEF_02101 5.7e-68 pepO 3.4.24.71 O Peptidase family M13
HICMHLEF_02102 4.9e-128 lplA 6.3.1.20 H Lipoate-protein ligase
HICMHLEF_02103 1.8e-56 lplA 6.3.1.20 H Lipoate-protein ligase
HICMHLEF_02104 1.9e-33
HICMHLEF_02105 2.3e-173 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HICMHLEF_02106 3.1e-74 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HICMHLEF_02107 1.4e-127 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HICMHLEF_02109 1.8e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HICMHLEF_02110 1.9e-106 ypsA S Belongs to the UPF0398 family
HICMHLEF_02111 1.5e-120 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HICMHLEF_02112 8.8e-160 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HICMHLEF_02113 9.2e-219 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HICMHLEF_02114 1.3e-85 comEB 3.5.4.12 F ComE operon protein 2
HICMHLEF_02115 2.4e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HICMHLEF_02116 2.4e-110 dnaD L DnaD domain protein
HICMHLEF_02117 1.3e-164 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HICMHLEF_02118 2e-80 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HICMHLEF_02119 7.8e-70 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HICMHLEF_02120 4.3e-138 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HICMHLEF_02121 2.1e-85 ypmB S Protein conserved in bacteria
HICMHLEF_02122 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HICMHLEF_02123 1.8e-72 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HICMHLEF_02124 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HICMHLEF_02125 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HICMHLEF_02126 6.1e-194 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HICMHLEF_02127 4.6e-166 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HICMHLEF_02128 3e-97 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HICMHLEF_02129 1.2e-58 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HICMHLEF_02130 7e-145 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HICMHLEF_02131 8.9e-30 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HICMHLEF_02132 2.1e-105 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HICMHLEF_02133 1.7e-145 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HICMHLEF_02134 4.7e-174
HICMHLEF_02135 1.4e-96
HICMHLEF_02136 2.8e-60 yitW S Iron-sulfur cluster assembly protein
HICMHLEF_02137 7.3e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HICMHLEF_02138 8.6e-23 icaC M Acyltransferase family
HICMHLEF_02139 5.8e-159 ykoT GT2 M Glycosyl transferase family 2
HICMHLEF_02140 2.9e-79 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HICMHLEF_02141 3.3e-100 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HICMHLEF_02142 1.6e-85
HICMHLEF_02143 1.5e-253 wcaJ M Bacterial sugar transferase
HICMHLEF_02144 1.4e-133 M Glycosyltransferase sugar-binding region containing DXD motif
HICMHLEF_02145 5.3e-97 tuaG GT2 M Glycosyltransferase like family 2
HICMHLEF_02146 9.2e-175 cps2D 5.1.3.2 M RmlD substrate binding domain
HICMHLEF_02147 1.1e-110 glnP P ABC transporter permease
HICMHLEF_02148 7.3e-142 glnH ET ABC transporter substrate-binding protein
HICMHLEF_02149 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HICMHLEF_02150 1.3e-171
HICMHLEF_02152 5.6e-85 zur P Belongs to the Fur family
HICMHLEF_02153 1.8e-08
HICMHLEF_02154 9.3e-112 gmk2 2.7.4.8 F Guanylate kinase
HICMHLEF_02155 2.8e-67 K Acetyltransferase (GNAT) domain
HICMHLEF_02156 5e-125 spl M NlpC/P60 family
HICMHLEF_02157 2e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HICMHLEF_02158 2.6e-161 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HICMHLEF_02159 1.4e-53 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HICMHLEF_02160 8.4e-64 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HICMHLEF_02161 6.5e-75 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HICMHLEF_02162 2.9e-41 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HICMHLEF_02163 3.5e-56 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HICMHLEF_02164 8.8e-239 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HICMHLEF_02165 1.6e-235 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HICMHLEF_02166 1.3e-226 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HICMHLEF_02167 5.8e-160 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HICMHLEF_02168 1.6e-111 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HICMHLEF_02169 5.9e-46 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HICMHLEF_02170 7.8e-127 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HICMHLEF_02171 1.9e-41 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HICMHLEF_02172 1.2e-126 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HICMHLEF_02173 2.5e-33 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HICMHLEF_02174 2.3e-158 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HICMHLEF_02175 2.6e-48 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HICMHLEF_02176 1.4e-18 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HICMHLEF_02177 2.1e-93 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HICMHLEF_02178 3.2e-109 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HICMHLEF_02179 3e-114 ylcC 3.4.22.70 M Sortase family
HICMHLEF_02180 9.8e-144 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HICMHLEF_02181 0.0 fbp 3.1.3.11 G phosphatase activity
HICMHLEF_02182 5.7e-65 nrp 1.20.4.1 P ArsC family
HICMHLEF_02183 1.9e-178 clpL O associated with various cellular activities
HICMHLEF_02184 9.9e-183 clpL O associated with various cellular activities
HICMHLEF_02186 7.6e-143 ywqE 3.1.3.48 GM PHP domain protein
HICMHLEF_02187 5e-154 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HICMHLEF_02188 1.7e-53 capM M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HICMHLEF_02189 7.2e-78 GT4 M COG0438 Glycosyltransferase
HICMHLEF_02190 3.2e-17 GM Polysaccharide pyruvyl transferase
HICMHLEF_02191 4.6e-25 kilA K BRO family, N-terminal domain
HICMHLEF_02192 9.9e-39 S sequence-specific DNA binding
HICMHLEF_02193 3e-94 S sequence-specific DNA binding
HICMHLEF_02194 1.9e-09 S Membrane
HICMHLEF_02195 1.1e-15 S Membrane
HICMHLEF_02197 1.1e-52 L Belongs to the 'phage' integrase family
HICMHLEF_02198 4.1e-130 L Belongs to the 'phage' integrase family
HICMHLEF_02200 7.1e-127 M Glycosyl hydrolases family 25
HICMHLEF_02201 1e-77 M Glycosyl hydrolases family 25
HICMHLEF_02202 9.8e-66 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HICMHLEF_02204 8.8e-63
HICMHLEF_02206 1.5e-32
HICMHLEF_02207 0.0 S peptidoglycan catabolic process
HICMHLEF_02208 1.7e-300 S Phage tail protein
HICMHLEF_02209 6.5e-289 xkdO M Phage tail tape measure protein TP901
HICMHLEF_02210 1.9e-36
HICMHLEF_02211 1.5e-53 S Phage tail assembly chaperone proteins, TAC
HICMHLEF_02212 6.3e-100 S Pfam:Phage_TTP_1
HICMHLEF_02213 3.3e-34 S Protein of unknown function (DUF806)
HICMHLEF_02214 3.6e-62 S exonuclease activity
HICMHLEF_02215 1.8e-51 S Phage head-tail joining protein
HICMHLEF_02216 1.5e-09
HICMHLEF_02217 1.3e-106 S Phage capsid family
HICMHLEF_02219 1.8e-61 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HICMHLEF_02220 1.8e-56 S Phage portal protein
HICMHLEF_02221 1e-16 S Phage portal protein
HICMHLEF_02223 1.6e-263 S Phage Terminase
HICMHLEF_02224 3.2e-38 L Phage terminase, small subunit
HICMHLEF_02225 6.6e-39 L HNH nucleases
HICMHLEF_02227 1e-40
HICMHLEF_02228 1.2e-97 S HNH endonuclease
HICMHLEF_02229 2e-238
HICMHLEF_02232 3.6e-76
HICMHLEF_02234 9.8e-42 S YopX protein
HICMHLEF_02235 7e-34
HICMHLEF_02237 7.3e-39 S Protein of unknown function (DUF1642)
HICMHLEF_02239 8e-140 S C-5 cytosine-specific DNA methylase
HICMHLEF_02240 6.9e-14
HICMHLEF_02241 8.1e-22
HICMHLEF_02242 8.7e-28
HICMHLEF_02244 2.4e-234 S DNA helicase activity
HICMHLEF_02245 4.3e-115 S calcium ion binding
HICMHLEF_02246 6.6e-104 S Protein of unknown function (DUF669)
HICMHLEF_02247 9.5e-132 S AAA domain
HICMHLEF_02248 4.5e-80 S Siphovirus Gp157
HICMHLEF_02253 4.8e-15
HICMHLEF_02256 8e-110 S Phage regulatory protein Rha (Phage_pRha)
HICMHLEF_02257 4.6e-25 kilA K BRO family, N-terminal domain
HICMHLEF_02258 9.9e-39 S sequence-specific DNA binding
HICMHLEF_02259 3e-94 S sequence-specific DNA binding
HICMHLEF_02260 1.4e-07 S Membrane
HICMHLEF_02261 1.1e-15 S Membrane
HICMHLEF_02263 2.4e-95 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HICMHLEF_02264 2.5e-86 K Acetyltransferase (GNAT) domain
HICMHLEF_02265 7.9e-61 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HICMHLEF_02266 6.4e-15 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HICMHLEF_02267 1.8e-56 K Transcriptional regulator PadR-like family
HICMHLEF_02268 8.4e-44 ORF00048
HICMHLEF_02269 5.8e-25 ORF00048
HICMHLEF_02270 1.8e-25 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HICMHLEF_02271 1.2e-88 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HICMHLEF_02272 6.3e-168 yjjC V ABC transporter
HICMHLEF_02273 7.3e-125 M Exporter of polyketide antibiotics
HICMHLEF_02274 9.9e-144 M Exporter of polyketide antibiotics
HICMHLEF_02275 8.9e-113 K Transcriptional regulator
HICMHLEF_02276 6.5e-257 ypiB EGP Major facilitator Superfamily
HICMHLEF_02277 1.1e-127 S membrane transporter protein
HICMHLEF_02278 1.6e-166 K Helix-turn-helix domain
HICMHLEF_02279 1.6e-71 S Alpha beta hydrolase
HICMHLEF_02280 3.6e-61 yvoA_1 K Transcriptional regulator, GntR family
HICMHLEF_02281 9.4e-127 skfE V ATPases associated with a variety of cellular activities
HICMHLEF_02282 1.8e-16
HICMHLEF_02283 3.7e-38
HICMHLEF_02284 2.7e-93
HICMHLEF_02285 4.9e-88 V ATPases associated with a variety of cellular activities
HICMHLEF_02286 1.3e-162 oppF P Oligopeptide/dipeptide transporter, C-terminal region
HICMHLEF_02287 2.2e-196 oppD P Oligopeptide/dipeptide transporter, C-terminal region
HICMHLEF_02288 1.7e-48
HICMHLEF_02289 3e-173 amiD P N-terminal TM domain of oligopeptide transport permease C
HICMHLEF_02290 1.9e-104 oppB P Binding-protein-dependent transport system inner membrane component
HICMHLEF_02291 1.1e-54 oppB P Binding-protein-dependent transport system inner membrane component
HICMHLEF_02292 2.1e-299 E Bacterial extracellular solute-binding proteins, family 5 Middle
HICMHLEF_02293 7.6e-19
HICMHLEF_02294 6.4e-288 V ABC transporter transmembrane region
HICMHLEF_02295 2.5e-220 V ABC transporter transmembrane region
HICMHLEF_02296 5.3e-39 V ABC transporter transmembrane region
HICMHLEF_02297 9.3e-68 S Iron-sulphur cluster biosynthesis
HICMHLEF_02298 9e-137 2.7.1.39 S Phosphotransferase enzyme family
HICMHLEF_02299 1.5e-114 zmp3 O Zinc-dependent metalloprotease
HICMHLEF_02300 2.7e-23 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HICMHLEF_02302 4.7e-85 lytN 3.5.1.104 M LysM domain
HICMHLEF_02303 0.0 lytN 3.5.1.104 M LysM domain
HICMHLEF_02305 8e-49 lciIC K Helix-turn-helix XRE-family like proteins
HICMHLEF_02306 5.9e-94 L restriction endonuclease
HICMHLEF_02307 5.8e-37 L Plasmid pRiA4b ORF-3-like protein
HICMHLEF_02309 1.3e-24 K Cro/C1-type HTH DNA-binding domain
HICMHLEF_02314 1.8e-13 M LysM domain
HICMHLEF_02315 4.6e-56
HICMHLEF_02316 2.6e-50 K Putative DNA-binding domain
HICMHLEF_02317 4.2e-22 oatA I Acyltransferase
HICMHLEF_02318 9.4e-183 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HICMHLEF_02319 4.3e-141 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HICMHLEF_02320 1.3e-46 yrvD S Lipopolysaccharide assembly protein A domain
HICMHLEF_02321 3.2e-115 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HICMHLEF_02322 1.6e-205 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HICMHLEF_02323 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HICMHLEF_02324 9.6e-95 M1-874 K Domain of unknown function (DUF1836)
HICMHLEF_02325 1.7e-298 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
HICMHLEF_02326 1.2e-144
HICMHLEF_02327 0.0 dnaE 2.7.7.7 L DNA polymerase
HICMHLEF_02328 9.8e-14 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HICMHLEF_02329 2.8e-151 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HICMHLEF_02330 4.2e-300 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HICMHLEF_02331 7.2e-72 yeaL S Protein of unknown function (DUF441)
HICMHLEF_02332 3.4e-163 cvfB S S1 domain
HICMHLEF_02333 1.1e-63 xerD D recombinase XerD
HICMHLEF_02334 7.6e-85 xerD D recombinase XerD
HICMHLEF_02335 3.4e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HICMHLEF_02336 7.3e-127 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HICMHLEF_02337 3.3e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HICMHLEF_02338 9.4e-138 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HICMHLEF_02339 2.4e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HICMHLEF_02340 9.8e-21 fer C 4Fe-4S single cluster domain of Ferredoxin I
HICMHLEF_02341 1e-179 ypbB 5.1.3.1 S Helix-turn-helix domain
HICMHLEF_02342 1.3e-265 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HICMHLEF_02343 6.8e-49 M Lysin motif
HICMHLEF_02344 1.5e-86 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HICMHLEF_02345 1.1e-218 rpsA 1.17.7.4 J Ribosomal protein S1
HICMHLEF_02346 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HICMHLEF_02347 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HICMHLEF_02348 2e-141 S Tetratricopeptide repeat protein
HICMHLEF_02349 5e-78 S Tetratricopeptide repeat protein
HICMHLEF_02350 4.8e-149 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HICMHLEF_02351 2.8e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HICMHLEF_02352 9.6e-85
HICMHLEF_02353 0.0 yfmR S ABC transporter, ATP-binding protein
HICMHLEF_02354 1.5e-185 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HICMHLEF_02355 7.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HICMHLEF_02356 1.9e-101 hly S protein, hemolysin III
HICMHLEF_02357 1.5e-147 DegV S EDD domain protein, DegV family
HICMHLEF_02358 7.8e-157 ypmR E GDSL-like Lipase/Acylhydrolase
HICMHLEF_02359 5.8e-112 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HICMHLEF_02360 2.1e-96 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HICMHLEF_02361 5.6e-25 yozE S Belongs to the UPF0346 family
HICMHLEF_02362 3e-257 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HICMHLEF_02363 5.7e-08
HICMHLEF_02366 1.1e-53 S Virulence-associated protein E
HICMHLEF_02369 2.8e-79 terS L Phage terminase, small subunit
HICMHLEF_02370 5.9e-67 terL S overlaps another CDS with the same product name
HICMHLEF_02371 3.1e-245 terL S overlaps another CDS with the same product name
HICMHLEF_02372 2.5e-10
HICMHLEF_02373 6.5e-218 S Phage portal protein
HICMHLEF_02374 1.1e-93 S Phage capsid family
HICMHLEF_02375 3.9e-165 S Phage capsid family
HICMHLEF_02376 1.3e-45 S Phage gp6-like head-tail connector protein
HICMHLEF_02377 9.6e-13 S Phage head-tail joining protein
HICMHLEF_02378 2.9e-16
HICMHLEF_02379 2.2e-14 ytgB S Transglycosylase associated protein
HICMHLEF_02380 5.8e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HICMHLEF_02382 1.7e-69 S SdpI/YhfL protein family
HICMHLEF_02383 3.1e-133 K response regulator
HICMHLEF_02384 2.4e-273 yclK 2.7.13.3 T Histidine kinase
HICMHLEF_02385 1.3e-93 yhbS S acetyltransferase
HICMHLEF_02386 7.6e-31
HICMHLEF_02387 5.2e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
HICMHLEF_02388 3.8e-82
HICMHLEF_02389 5.3e-59
HICMHLEF_02390 3.8e-251 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HICMHLEF_02392 6.6e-186 S response to antibiotic
HICMHLEF_02393 1.7e-94 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HICMHLEF_02394 3.6e-46 yjgN S Bacterial protein of unknown function (DUF898)
HICMHLEF_02395 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HICMHLEF_02396 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HICMHLEF_02397 4.9e-48 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HICMHLEF_02398 2.3e-109 camS S sex pheromone
HICMHLEF_02399 1.1e-83 camS S sex pheromone
HICMHLEF_02400 4.9e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HICMHLEF_02401 8.8e-265 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HICMHLEF_02402 7.8e-20 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HICMHLEF_02403 1.5e-241 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HICMHLEF_02404 2.9e-193 yegS 2.7.1.107 G Lipid kinase
HICMHLEF_02405 5.7e-250 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HICMHLEF_02406 2.4e-215 yttB EGP Major facilitator Superfamily
HICMHLEF_02407 1.6e-143 cof S Sucrose-6F-phosphate phosphohydrolase
HICMHLEF_02408 2.5e-39 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HICMHLEF_02409 7.2e-105 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HICMHLEF_02410 7.3e-144 pepO 3.4.24.71 O Peptidase family M13
HICMHLEF_02411 2.2e-212 pepO 3.4.24.71 O Peptidase family M13
HICMHLEF_02412 6e-79 K Acetyltransferase (GNAT) domain
HICMHLEF_02413 4e-164 degV S Uncharacterised protein, DegV family COG1307
HICMHLEF_02414 1.4e-119 qmcA O prohibitin homologues
HICMHLEF_02415 3.2e-29
HICMHLEF_02416 4.3e-09 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HICMHLEF_02417 4e-133 lys M Glycosyl hydrolases family 25
HICMHLEF_02418 2.9e-39 S Protein of unknown function (DUF1093)
HICMHLEF_02419 2e-61 S Domain of unknown function (DUF4828)
HICMHLEF_02420 1.9e-21 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HICMHLEF_02425 1.3e-221 3.1.1.32, 3.1.1.4 S COG0790 FOG TPR repeat, SEL1 subfamily
HICMHLEF_02427 1.3e-116 L Protein of unknown function (DUF3991)
HICMHLEF_02428 1.9e-298 L Protein of unknown function (DUF3991)
HICMHLEF_02429 1.2e-64
HICMHLEF_02430 3e-16
HICMHLEF_02431 5.8e-23
HICMHLEF_02432 1.1e-34
HICMHLEF_02434 4.4e-74
HICMHLEF_02435 8.6e-146 F DNA/RNA non-specific endonuclease
HICMHLEF_02437 4.6e-82 tnp2PF3 L Transposase DDE domain
HICMHLEF_02438 5.9e-51 L Transposase and inactivated derivatives, IS30 family
HICMHLEF_02439 0.0 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_02440 5.7e-112 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HICMHLEF_02441 7.3e-80 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HICMHLEF_02442 2.5e-46 sgcB 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_02443 1.2e-244 G PTS system sugar-specific permease component
HICMHLEF_02444 9.1e-225 dgoD 4.2.1.6 M Mandelate racemase muconate lactonizing enzyme
HICMHLEF_02445 1.3e-76
HICMHLEF_02447 3.5e-25 chpR T PFAM SpoVT AbrB
HICMHLEF_02448 2.5e-132 L Transposase, IS116 IS110 IS902 family
HICMHLEF_02449 1.1e-124 tnp L DDE domain
HICMHLEF_02450 4.6e-134 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HICMHLEF_02451 2.5e-22 L recombinase activity
HICMHLEF_02452 1.2e-70 tnpR L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HICMHLEF_02453 5.1e-113 tnp L DDE domain
HICMHLEF_02454 1.1e-32 L Integrase core domain
HICMHLEF_02455 9.7e-103 L Bacterial dnaA protein
HICMHLEF_02456 1.1e-113 L Transposase
HICMHLEF_02457 8.1e-155 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
HICMHLEF_02458 3.8e-10 agaC G PTS system sorbose-specific iic component
HICMHLEF_02459 8.7e-84 agaC G PTS system sorbose-specific iic component
HICMHLEF_02460 6.8e-121 G PTS system mannose/fructose/sorbose family IID component
HICMHLEF_02461 2e-31 G PTS system fructose IIA component
HICMHLEF_02462 9.1e-73 L Resolvase, N terminal domain
HICMHLEF_02463 2.1e-25 nrdI F Belongs to the NrdI family
HICMHLEF_02465 4.1e-149 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HICMHLEF_02466 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HICMHLEF_02467 2.8e-268 L Transposase DDE domain
HICMHLEF_02468 3.3e-29 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HICMHLEF_02469 8.6e-15
HICMHLEF_02470 3.1e-240 V ABC transporter
HICMHLEF_02471 1.1e-75 V ABC transporter
HICMHLEF_02472 0.0 V ATPases associated with a variety of cellular activities
HICMHLEF_02473 8e-208 EGP Transmembrane secretion effector
HICMHLEF_02474 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HICMHLEF_02475 7e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HICMHLEF_02476 4.8e-103 K Bacterial regulatory proteins, tetR family
HICMHLEF_02478 8e-169 yxeA V FtsX-like permease family
HICMHLEF_02479 1.3e-125 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
HICMHLEF_02480 6.4e-34
HICMHLEF_02481 2e-135 tipA K TipAS antibiotic-recognition domain
HICMHLEF_02482 4.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HICMHLEF_02483 1.6e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HICMHLEF_02484 2.2e-162 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HICMHLEF_02485 2.5e-100 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HICMHLEF_02486 1.7e-77
HICMHLEF_02487 3.1e-60 rplQ J Ribosomal protein L17
HICMHLEF_02488 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HICMHLEF_02489 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HICMHLEF_02490 2.1e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HICMHLEF_02491 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HICMHLEF_02492 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HICMHLEF_02493 1.4e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HICMHLEF_02494 9.8e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HICMHLEF_02495 1.1e-16 rplO J Binds to the 23S rRNA
HICMHLEF_02496 8e-37 rplO J Binds to the 23S rRNA
HICMHLEF_02497 1.7e-24 rpmD J Ribosomal protein L30
HICMHLEF_02498 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HICMHLEF_02499 4.6e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HICMHLEF_02500 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HICMHLEF_02501 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HICMHLEF_02502 1.5e-80 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HICMHLEF_02503 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HICMHLEF_02504 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HICMHLEF_02505 1.4e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HICMHLEF_02506 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HICMHLEF_02507 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HICMHLEF_02508 3.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HICMHLEF_02509 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HICMHLEF_02510 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HICMHLEF_02511 3.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HICMHLEF_02512 4.5e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HICMHLEF_02513 5.9e-109 rplD J Forms part of the polypeptide exit tunnel
HICMHLEF_02514 3.4e-106 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HICMHLEF_02515 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HICMHLEF_02516 1.2e-68 psiE S Phosphate-starvation-inducible E
HICMHLEF_02517 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HICMHLEF_02518 1.7e-93 yfjR K WYL domain
HICMHLEF_02519 1.3e-94 yfjR K WYL domain
HICMHLEF_02520 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HICMHLEF_02521 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HICMHLEF_02522 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HICMHLEF_02523 7.8e-18 M domain protein
HICMHLEF_02524 5e-133 M domain protein
HICMHLEF_02525 2.8e-156 M domain protein
HICMHLEF_02526 2.7e-147 yicL EG EamA-like transporter family
HICMHLEF_02527 1.9e-112 tag 3.2.2.20 L glycosylase
HICMHLEF_02528 4.2e-77 usp5 T universal stress protein
HICMHLEF_02529 6.5e-64 K Helix-turn-helix XRE-family like proteins
HICMHLEF_02530 4.9e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
HICMHLEF_02531 5e-223 queG 1.17.99.6 C Domain of unknown function (DUF1730)
HICMHLEF_02532 4.1e-62
HICMHLEF_02533 4.9e-14 bioY S BioY family
HICMHLEF_02534 2.4e-63 bioY S BioY family
HICMHLEF_02536 4.2e-102 Q methyltransferase
HICMHLEF_02537 4.5e-97 T Sh3 type 3 domain protein
HICMHLEF_02538 1.9e-33 yfeJ 6.3.5.2 F glutamine amidotransferase
HICMHLEF_02539 1.5e-70 yfeJ 6.3.5.2 F glutamine amidotransferase
HICMHLEF_02540 8e-137 S Uncharacterized protein conserved in bacteria (DUF2263)
HICMHLEF_02541 4.9e-257 yhdP S Transporter associated domain
HICMHLEF_02542 7.2e-144 S Alpha beta hydrolase
HICMHLEF_02543 1e-147 I Acyltransferase
HICMHLEF_02544 3.1e-262 lmrB EGP Major facilitator Superfamily
HICMHLEF_02545 8.8e-84 S Domain of unknown function (DUF4811)
HICMHLEF_02546 4.2e-95 maf D nucleoside-triphosphate diphosphatase activity
HICMHLEF_02547 9.3e-135 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HICMHLEF_02548 2.8e-219 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HICMHLEF_02549 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HICMHLEF_02550 2.6e-52 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HICMHLEF_02551 0.0 ydaO E amino acid
HICMHLEF_02552 1.1e-56 S Domain of unknown function (DUF1827)
HICMHLEF_02553 4.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HICMHLEF_02554 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HICMHLEF_02555 8.6e-09 ydiL S CAAX protease self-immunity
HICMHLEF_02556 7.5e-56 ydiL S CAAX protease self-immunity
HICMHLEF_02557 3.7e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HICMHLEF_02558 1.6e-129
HICMHLEF_02559 2.1e-61 ytrB V ABC transporter
HICMHLEF_02560 2e-84 ytrB V ABC transporter
HICMHLEF_02561 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HICMHLEF_02562 2.8e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HICMHLEF_02563 1.8e-45 uup S ABC transporter, ATP-binding protein
HICMHLEF_02564 2e-112 uup S ABC transporter, ATP-binding protein
HICMHLEF_02565 1e-190 uup S ABC transporter, ATP-binding protein
HICMHLEF_02566 1.6e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_02567 1.8e-187 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HICMHLEF_02568 2.3e-98 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HICMHLEF_02569 5.3e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HICMHLEF_02570 7e-119
HICMHLEF_02571 4.9e-52 E lipolytic protein G-D-S-L family
HICMHLEF_02572 6.7e-62 E lipolytic protein G-D-S-L family
HICMHLEF_02573 1.2e-49 ccl S QueT transporter
HICMHLEF_02574 3.5e-126 IQ Enoyl-(Acyl carrier protein) reductase
HICMHLEF_02575 2.4e-36 XK27_01315 S Protein of unknown function (DUF2829)
HICMHLEF_02576 5e-48 K Cro/C1-type HTH DNA-binding domain
HICMHLEF_02577 4.7e-76 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
HICMHLEF_02578 4.7e-28 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
HICMHLEF_02579 5.3e-181 oppF P Belongs to the ABC transporter superfamily
HICMHLEF_02580 1.2e-48 oppD P Belongs to the ABC transporter superfamily
HICMHLEF_02581 8.9e-139 oppD P Belongs to the ABC transporter superfamily
HICMHLEF_02582 3.1e-176 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HICMHLEF_02583 3e-162 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HICMHLEF_02584 7.4e-305 oppA E ABC transporter, substratebinding protein
HICMHLEF_02585 1e-252 EGP Major facilitator Superfamily
HICMHLEF_02586 8.5e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HICMHLEF_02587 3.4e-129 yrjD S LUD domain
HICMHLEF_02588 3.6e-290 lutB C 4Fe-4S dicluster domain
HICMHLEF_02589 1.1e-147 lutA C Cysteine-rich domain
HICMHLEF_02590 6.3e-91
HICMHLEF_02591 9.5e-53 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HICMHLEF_02592 1.6e-210 S Bacterial protein of unknown function (DUF871)
HICMHLEF_02593 5.8e-58 S Domain of unknown function (DUF3284)
HICMHLEF_02594 9.2e-259 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HICMHLEF_02595 0.0 rafA 3.2.1.22 G alpha-galactosidase
HICMHLEF_02596 5.9e-132 S Belongs to the UPF0246 family
HICMHLEF_02597 1.5e-132 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
HICMHLEF_02598 2.2e-229 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
HICMHLEF_02599 3e-254 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
HICMHLEF_02600 3.9e-110
HICMHLEF_02601 9e-102 S WxL domain surface cell wall-binding
HICMHLEF_02602 1.3e-145 frlD 2.7.1.218 G pfkB family carbohydrate kinase
HICMHLEF_02603 2.7e-288 G Phosphodiester glycosidase
HICMHLEF_02604 3.9e-107 L Transposase and inactivated derivatives, IS30 family
HICMHLEF_02605 1.5e-10 recO L Involved in DNA repair and RecF pathway recombination
HICMHLEF_02606 1.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HICMHLEF_02607 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HICMHLEF_02608 3.3e-58 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HICMHLEF_02609 4.6e-27 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HICMHLEF_02610 1.4e-41 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HICMHLEF_02611 1e-87 phoH T phosphate starvation-inducible protein PhoH
HICMHLEF_02612 4.2e-78 phoH T phosphate starvation-inducible protein PhoH
HICMHLEF_02613 1.6e-68 yqeY S YqeY-like protein
HICMHLEF_02614 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HICMHLEF_02615 4.6e-64 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HICMHLEF_02616 2.3e-56 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HICMHLEF_02617 4.7e-168 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HICMHLEF_02618 9.4e-124 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HICMHLEF_02619 9.4e-33 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HICMHLEF_02620 1.1e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HICMHLEF_02621 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HICMHLEF_02622 3.9e-57 hisS 6.1.1.21 J histidyl-tRNA synthetase
HICMHLEF_02623 2.3e-173 hisS 6.1.1.21 J histidyl-tRNA synthetase
HICMHLEF_02624 1.5e-60
HICMHLEF_02625 7.6e-127
HICMHLEF_02626 5.6e-158 V ABC transporter
HICMHLEF_02627 9.4e-63 FG adenosine 5'-monophosphoramidase activity
HICMHLEF_02628 5.2e-248 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
HICMHLEF_02629 7.2e-115 3.1.3.18 J HAD-hyrolase-like
HICMHLEF_02630 5.2e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HICMHLEF_02631 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HICMHLEF_02632 4e-53
HICMHLEF_02633 3e-57 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HICMHLEF_02634 1.3e-61 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HICMHLEF_02635 2.9e-151 prmA J Ribosomal protein L11 methyltransferase
HICMHLEF_02636 6e-14 prmA J Ribosomal protein L11 methyltransferase
HICMHLEF_02637 2e-83 XK27_03960 S Protein of unknown function (DUF3013)
HICMHLEF_02638 6.5e-69 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HICMHLEF_02639 7.8e-47 L Transposase and inactivated derivatives, IS30 family
HICMHLEF_02640 6.4e-116 L Transposase and inactivated derivatives, IS30 family
HICMHLEF_02641 2.8e-67 S peptidase
HICMHLEF_02642 3.4e-185 3.1.1.5 I Serine aminopeptidase, S33
HICMHLEF_02643 2.6e-57 L Transposase
HICMHLEF_02644 9.6e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HICMHLEF_02645 1e-47 tnp2PF3 L Transposase DDE domain
HICMHLEF_02646 3e-22 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HICMHLEF_02647 3e-137 L COG2801 Transposase and inactivated derivatives
HICMHLEF_02648 2.1e-42 L Transposase
HICMHLEF_02649 1.2e-96 repE K Primase C terminal 1 (PriCT-1)
HICMHLEF_02650 3.6e-91 soj D AAA domain
HICMHLEF_02651 1.6e-20
HICMHLEF_02652 4.7e-235 L Transposase
HICMHLEF_02653 1.4e-172 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HICMHLEF_02654 1.4e-83 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
HICMHLEF_02662 1.2e-17
HICMHLEF_02663 7e-81 yttB EGP Major facilitator Superfamily
HICMHLEF_02664 1.8e-87 lmrP E Major Facilitator Superfamily
HICMHLEF_02665 2.2e-284 pipD E Dipeptidase
HICMHLEF_02669 9.2e-18
HICMHLEF_02670 8.7e-09
HICMHLEF_02671 1e-131 G Phosphoglycerate mutase family
HICMHLEF_02672 5.4e-121 K Bacterial regulatory proteins, tetR family
HICMHLEF_02673 0.0 ycfI V ABC transporter, ATP-binding protein
HICMHLEF_02674 1.3e-214 yfiC V ABC transporter
HICMHLEF_02675 9.4e-118 yfiC V ABC transporter
HICMHLEF_02676 2.3e-139 S NADPH-dependent FMN reductase
HICMHLEF_02677 1.2e-40 1.13.11.2 S glyoxalase
HICMHLEF_02678 5.6e-115 1.13.11.2 S glyoxalase
HICMHLEF_02679 1.7e-111 ampC V Beta-lactamase
HICMHLEF_02680 3.6e-114 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HICMHLEF_02681 1.2e-126 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HICMHLEF_02682 6e-111 tdk 2.7.1.21 F thymidine kinase
HICMHLEF_02683 4.8e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HICMHLEF_02684 1.3e-33 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HICMHLEF_02685 9.3e-101 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HICMHLEF_02686 1.3e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HICMHLEF_02687 5.7e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HICMHLEF_02688 1.3e-111 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HICMHLEF_02689 3.9e-125 atpB C it plays a direct role in the translocation of protons across the membrane
HICMHLEF_02690 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HICMHLEF_02691 4.7e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HICMHLEF_02692 2.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HICMHLEF_02693 3e-273 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HICMHLEF_02694 2e-71 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HICMHLEF_02695 4.1e-84 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HICMHLEF_02696 4.1e-07 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HICMHLEF_02697 5.2e-44 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HICMHLEF_02698 2.2e-177 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HICMHLEF_02699 1.5e-84 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HICMHLEF_02700 3.1e-47 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HICMHLEF_02701 1.3e-28 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HICMHLEF_02702 5.4e-44 ylxQ J ribosomal protein
HICMHLEF_02703 1.5e-46 ylxR K Protein of unknown function (DUF448)
HICMHLEF_02704 2.3e-202 nusA K Participates in both transcription termination and antitermination
HICMHLEF_02705 1e-84 rimP J Required for maturation of 30S ribosomal subunits
HICMHLEF_02706 3.3e-109 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HICMHLEF_02707 1e-193 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HICMHLEF_02708 2e-40 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HICMHLEF_02709 1.4e-110 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HICMHLEF_02710 2.8e-236 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HICMHLEF_02711 3.5e-53 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HICMHLEF_02712 2.8e-249 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HICMHLEF_02713 3e-52 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HICMHLEF_02714 4.1e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HICMHLEF_02715 7.3e-141 cdsA 2.7.7.41 S Belongs to the CDS family
HICMHLEF_02716 1.9e-110 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HICMHLEF_02717 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HICMHLEF_02718 8.5e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HICMHLEF_02719 3.5e-32 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HICMHLEF_02720 3.9e-114 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HICMHLEF_02721 1.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HICMHLEF_02722 1.3e-47 yazA L GIY-YIG catalytic domain protein
HICMHLEF_02723 4.8e-134 yabB 2.1.1.223 L Methyltransferase small domain
HICMHLEF_02724 2.2e-122 plsC 2.3.1.51 I Acyltransferase
HICMHLEF_02725 5e-201 bcaP E Amino Acid
HICMHLEF_02726 2.6e-138 yejC S Protein of unknown function (DUF1003)
HICMHLEF_02727 0.0 mdlB V ABC transporter
HICMHLEF_02728 2e-71 mdlA V ABC transporter
HICMHLEF_02729 2.7e-62 mdlA V ABC transporter
HICMHLEF_02730 4.3e-164 mdlA V ABC transporter
HICMHLEF_02731 4.8e-29 yneF S UPF0154 protein
HICMHLEF_02732 1.1e-30 ynzC S UPF0291 protein
HICMHLEF_02733 1.1e-25
HICMHLEF_02734 4.3e-19 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HICMHLEF_02735 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HICMHLEF_02736 3.1e-147 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HICMHLEF_02737 1.2e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HICMHLEF_02738 8.4e-38 ylqC S Belongs to the UPF0109 family
HICMHLEF_02739 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HICMHLEF_02740 1.2e-229 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HICMHLEF_02741 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HICMHLEF_02742 6.8e-24
HICMHLEF_02743 8.8e-53
HICMHLEF_02744 2e-17
HICMHLEF_02745 5.3e-279 mntH P H( )-stimulated, divalent metal cation uptake system
HICMHLEF_02746 0.0 pacL P P-type ATPase
HICMHLEF_02747 9.8e-64
HICMHLEF_02748 1.2e-86 EGP Major Facilitator Superfamily
HICMHLEF_02749 3e-137 EGP Major Facilitator Superfamily
HICMHLEF_02750 2.1e-311 mco Q Multicopper oxidase
HICMHLEF_02751 1e-24
HICMHLEF_02752 4.2e-81 2.5.1.105 P Cation efflux family
HICMHLEF_02753 8.7e-51 czrA K Transcriptional regulator, ArsR family
HICMHLEF_02754 5.4e-175 sitA P Belongs to the bacterial solute-binding protein 9 family
HICMHLEF_02755 9.5e-145 mtsB U ABC 3 transport family
HICMHLEF_02756 4.2e-130 mntB 3.6.3.35 P ABC transporter
HICMHLEF_02757 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HICMHLEF_02758 7.7e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
HICMHLEF_02759 1.4e-118 GM NmrA-like family
HICMHLEF_02760 4.9e-85
HICMHLEF_02761 1.3e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
HICMHLEF_02762 1.8e-19
HICMHLEF_02764 1.7e-47 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HICMHLEF_02765 1.2e-52 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HICMHLEF_02766 1.4e-286 G MFS/sugar transport protein
HICMHLEF_02767 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase concanavalin-like domain
HICMHLEF_02768 7.4e-127 ssuA P NMT1-like family
HICMHLEF_02769 7.6e-33 ssuA P NMT1-like family
HICMHLEF_02770 1.4e-292 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
HICMHLEF_02771 3.4e-233 yfiQ I Acyltransferase family
HICMHLEF_02772 1.3e-120 ssuB P ATPases associated with a variety of cellular activities
HICMHLEF_02773 3.6e-73 ssuC U Binding-protein-dependent transport system inner membrane component
HICMHLEF_02774 7.2e-83 S B3/4 domain
HICMHLEF_02775 1.9e-26 S B3/4 domain
HICMHLEF_02776 4.9e-148 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HICMHLEF_02777 1.6e-07 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HICMHLEF_02778 5.6e-164 smc D Required for chromosome condensation and partitioning
HICMHLEF_02779 2.7e-298 smc D Required for chromosome condensation and partitioning
HICMHLEF_02780 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HICMHLEF_02781 0.0 oppA1 E ABC transporter substrate-binding protein
HICMHLEF_02782 1.4e-169 oppB P ABC transporter permease
HICMHLEF_02783 2.7e-79 oppF P Belongs to the ABC transporter superfamily
HICMHLEF_02784 1.5e-78 oppF P Belongs to the ABC transporter superfamily
HICMHLEF_02785 4.4e-194 oppD P Belongs to the ABC transporter superfamily
HICMHLEF_02786 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HICMHLEF_02787 1.4e-110 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HICMHLEF_02788 2.6e-180 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HICMHLEF_02789 3.9e-109 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HICMHLEF_02790 6.4e-70 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HICMHLEF_02791 4.7e-286 yloV S DAK2 domain fusion protein YloV
HICMHLEF_02792 2.3e-57 asp S Asp23 family, cell envelope-related function
HICMHLEF_02793 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HICMHLEF_02794 1.6e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
HICMHLEF_02795 9.7e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HICMHLEF_02796 3.5e-103 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HICMHLEF_02797 1.8e-184 KLT serine threonine protein kinase
HICMHLEF_02798 2.4e-64 KLT serine threonine protein kinase
HICMHLEF_02799 3.2e-41 KLT serine threonine protein kinase
HICMHLEF_02800 3e-99 stp 3.1.3.16 T phosphatase
HICMHLEF_02801 1.1e-27 stp 3.1.3.16 T phosphatase
HICMHLEF_02802 7e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HICMHLEF_02803 1.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HICMHLEF_02804 2.8e-54 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HICMHLEF_02805 2.4e-178 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HICMHLEF_02806 1.8e-156 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HICMHLEF_02807 5.2e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HICMHLEF_02808 2.9e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HICMHLEF_02809 3.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HICMHLEF_02810 1.3e-85 rssA S Patatin-like phospholipase
HICMHLEF_02811 4.2e-53
HICMHLEF_02812 1.1e-34 mraZ K Belongs to the MraZ family
HICMHLEF_02813 1.3e-35 mraZ K Belongs to the MraZ family
HICMHLEF_02814 5.3e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HICMHLEF_02815 6.2e-58 ftsL D cell division protein FtsL
HICMHLEF_02816 1e-48 ftsI 3.4.16.4 M Penicillin-binding Protein
HICMHLEF_02817 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HICMHLEF_02818 9.1e-10 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HICMHLEF_02819 4.5e-146 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HICMHLEF_02820 4.4e-194 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HICMHLEF_02821 7e-59 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HICMHLEF_02822 8.2e-39 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HICMHLEF_02823 1.7e-131 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HICMHLEF_02824 1.3e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HICMHLEF_02825 1.8e-190 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HICMHLEF_02826 7.8e-10 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HICMHLEF_02827 5.4e-218 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HICMHLEF_02828 6.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HICMHLEF_02829 5.2e-44 yggT D integral membrane protein
HICMHLEF_02830 1.4e-144 ylmH S S4 domain protein
HICMHLEF_02831 1.1e-80 divIVA D DivIVA protein
HICMHLEF_02832 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HICMHLEF_02833 8.2e-37 cspA K Cold shock protein
HICMHLEF_02834 2.2e-105 pstS P Phosphate
HICMHLEF_02835 8.1e-30 pstS P Phosphate
HICMHLEF_02836 5.2e-262 ydiC1 EGP Major facilitator Superfamily
HICMHLEF_02837 1.8e-207 yaaN P Toxic anion resistance protein (TelA)
HICMHLEF_02838 7.6e-115 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HICMHLEF_02839 7e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HICMHLEF_02840 5.8e-34
HICMHLEF_02841 2.4e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HICMHLEF_02842 6.7e-123 iscS 2.8.1.7 E Aminotransferase class V
HICMHLEF_02843 4.2e-43 iscS 2.8.1.7 E Aminotransferase class V
HICMHLEF_02844 2.6e-58 XK27_04120 S Putative amino acid metabolism
HICMHLEF_02845 0.0 uvrA2 L ABC transporter
HICMHLEF_02846 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HICMHLEF_02847 1.7e-32 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HICMHLEF_02848 6.2e-35 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HICMHLEF_02849 1.4e-81 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HICMHLEF_02850 6e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HICMHLEF_02851 7.5e-180 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HICMHLEF_02852 2.8e-310 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HICMHLEF_02853 1.3e-117 ybhL S Inhibitor of apoptosis-promoting Bax1
HICMHLEF_02854 6.8e-13 S Cell surface protein
HICMHLEF_02855 3e-151 S Cell surface protein
HICMHLEF_02856 2.1e-135 S WxL domain surface cell wall-binding
HICMHLEF_02857 0.0 N domain, Protein
HICMHLEF_02858 9.3e-29 N domain, Protein
HICMHLEF_02859 4.3e-123 N domain, Protein
HICMHLEF_02860 3.3e-239 K Mga helix-turn-helix domain
HICMHLEF_02862 9.9e-166 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HICMHLEF_02863 4.2e-80 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HICMHLEF_02864 2.8e-28 sftA D Belongs to the FtsK SpoIIIE SftA family
HICMHLEF_02865 8.8e-85 sftA D Belongs to the FtsK SpoIIIE SftA family
HICMHLEF_02866 7.9e-145 sftA D Belongs to the FtsK SpoIIIE SftA family
HICMHLEF_02867 3.1e-57 sftA D Belongs to the FtsK SpoIIIE SftA family
HICMHLEF_02869 1.6e-86 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HICMHLEF_02870 7.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HICMHLEF_02872 8.2e-63 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HICMHLEF_02873 4.5e-49 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HICMHLEF_02874 1.2e-148 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HICMHLEF_02876 4.2e-56 ecsB U ABC transporter
HICMHLEF_02877 4.8e-62 ecsB U ABC transporter
HICMHLEF_02878 1.4e-42 ecsB U ABC transporter
HICMHLEF_02879 2.6e-27 ecsA V ABC transporter, ATP-binding protein
HICMHLEF_02880 1.8e-84 ecsA V ABC transporter, ATP-binding protein
HICMHLEF_02881 5.5e-74 hit FG histidine triad
HICMHLEF_02882 7.4e-48 yhaH S YtxH-like protein
HICMHLEF_02883 1.2e-119 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HICMHLEF_02884 2.5e-23 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HICMHLEF_02885 2.2e-159 map 3.4.11.18 E Methionine Aminopeptidase
HICMHLEF_02886 3.4e-194 M Glycosyltransferase like family 2
HICMHLEF_02888 4.5e-29
HICMHLEF_02889 2.6e-197 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HICMHLEF_02890 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HICMHLEF_02891 4.1e-119 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HICMHLEF_02892 4.7e-56 M Glycosyl transferase family 8
HICMHLEF_02893 6.2e-39 M transferase activity, transferring glycosyl groups
HICMHLEF_02894 3.9e-163 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HICMHLEF_02895 9.7e-121 N domain, Protein
HICMHLEF_02896 2.2e-287 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HICMHLEF_02897 2.9e-171 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HICMHLEF_02898 8.7e-69 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HICMHLEF_02899 3.2e-41 S Bacterial membrane protein YfhO
HICMHLEF_02900 6e-201 S Bacterial membrane protein YfhO
HICMHLEF_02901 4e-210 S Bacterial membrane protein YfhO
HICMHLEF_02902 3e-304 S Psort location CytoplasmicMembrane, score
HICMHLEF_02903 1.6e-83 S Fic/DOC family
HICMHLEF_02904 2.1e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HICMHLEF_02905 4.4e-89
HICMHLEF_02907 5.8e-104 yqjA S Putative aromatic acid exporter C-terminal domain
HICMHLEF_02908 1.4e-47 yqjA S Putative aromatic acid exporter C-terminal domain
HICMHLEF_02909 0.0 yjbQ P TrkA C-terminal domain protein
HICMHLEF_02910 3.2e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HICMHLEF_02911 1.3e-80 yjhE S Phage tail protein
HICMHLEF_02912 7.2e-146 mntH P H( )-stimulated, divalent metal cation uptake system
HICMHLEF_02913 8e-61 mntH P H( )-stimulated, divalent metal cation uptake system
HICMHLEF_02914 1.4e-160 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HICMHLEF_02915 1.2e-128 pgm3 G Phosphoglycerate mutase family
HICMHLEF_02916 1.3e-90 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HICMHLEF_02917 7.4e-44 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HICMHLEF_02918 4.9e-277 V FtsX-like permease family
HICMHLEF_02919 1.1e-14 V FtsX-like permease family
HICMHLEF_02920 1.2e-135 cysA V ABC transporter, ATP-binding protein
HICMHLEF_02921 0.0 E amino acid
HICMHLEF_02922 8.5e-145 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HICMHLEF_02923 7.6e-107 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HICMHLEF_02924 6.2e-114 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HICMHLEF_02925 5.7e-111 nodB3 G Polysaccharide deacetylase
HICMHLEF_02926 0.0 M Sulfatase
HICMHLEF_02927 3e-174 S EpsG family
HICMHLEF_02928 7.4e-83 epsG 2.7.10.1 D Capsular exopolysaccharide family
HICMHLEF_02929 2.4e-83 ywqC M capsule polysaccharide biosynthetic process
HICMHLEF_02930 2.4e-96 S polysaccharide biosynthetic process
HICMHLEF_02931 7.3e-98 S polysaccharide biosynthetic process
HICMHLEF_02932 3e-27 S polysaccharide biosynthetic process
HICMHLEF_02933 4.3e-99 M Glycosyl Transferase
HICMHLEF_02934 3.8e-67 M Glycosyl Transferase
HICMHLEF_02935 7.5e-124 potC P ABC transporter permease
HICMHLEF_02936 1.6e-207 potD P ABC transporter
HICMHLEF_02937 1.1e-80 S Domain of unknown function (DUF5067)
HICMHLEF_02938 1.1e-31
HICMHLEF_02940 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
HICMHLEF_02941 2.2e-117 K Transcriptional regulator
HICMHLEF_02942 4.4e-29 V ABC transporter
HICMHLEF_02943 9.3e-135 V ABC transporter
HICMHLEF_02944 8.1e-126 V AAA domain, putative AbiEii toxin, Type IV TA system
HICMHLEF_02945 1e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HICMHLEF_02946 1.5e-168 ybbR S YbbR-like protein
HICMHLEF_02947 1.4e-219 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HICMHLEF_02948 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HICMHLEF_02949 0.0 pepF2 E Oligopeptidase F
HICMHLEF_02950 3.3e-91 S VanZ like family
HICMHLEF_02951 3.4e-132 yebC K Transcriptional regulatory protein
HICMHLEF_02952 1.3e-133 comGA NU Type II IV secretion system protein
HICMHLEF_02953 7.5e-164 comGB NU type II secretion system
HICMHLEF_02955 7.6e-32
HICMHLEF_02957 1.1e-47
HICMHLEF_02958 1.1e-80
HICMHLEF_02959 4.6e-49
HICMHLEF_02960 9.1e-11 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HICMHLEF_02961 1.7e-55 ypaA S Protein of unknown function (DUF1304)
HICMHLEF_02962 1.6e-75 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HICMHLEF_02963 9.1e-32 yxaB GM Polysaccharide pyruvyl transferase
HICMHLEF_02964 1.6e-165 repA S Replication initiator protein A
HICMHLEF_02965 8.7e-44 relB L Addiction module antitoxin, RelB DinJ family
HICMHLEF_02966 1.6e-85
HICMHLEF_02967 1.7e-23
HICMHLEF_02968 8.6e-90 L MobA MobL family protein
HICMHLEF_02969 5e-271 L MobA MobL family protein
HICMHLEF_02970 8.9e-26
HICMHLEF_02971 6.2e-257 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HICMHLEF_02972 4.9e-59 M Cna protein B-type domain
HICMHLEF_02973 3e-66 tnp2PF3 L manually curated
HICMHLEF_02974 4.1e-37 mntH P metal ion transmembrane transporter activity
HICMHLEF_02975 2.2e-137 corA P CorA-like Mg2+ transporter protein
HICMHLEF_02976 4e-11 corA P CorA-like Mg2+ transporter protein
HICMHLEF_02977 3.1e-56 tnp2PF3 L Transposase DDE domain
HICMHLEF_02978 1.2e-47 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HICMHLEF_02979 1.1e-65 tnp2PF3 L Transposase DDE domain
HICMHLEF_02980 4.2e-50 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
HICMHLEF_02981 1.5e-150 lacT K PRD domain
HICMHLEF_02982 1.6e-120 lacE 2.7.1.207 G Phosphotransferase system, EIIC
HICMHLEF_02983 4.9e-134 lacE 2.7.1.207 G Phosphotransferase system, EIIC
HICMHLEF_02984 2.8e-25 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
HICMHLEF_02985 3e-286 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HICMHLEF_02986 2.3e-51 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
HICMHLEF_02987 6.4e-137 L Integrase core domain
HICMHLEF_02996 3.6e-79 ctsR K Belongs to the CtsR family
HICMHLEF_02997 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HICMHLEF_02998 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HICMHLEF_02999 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HICMHLEF_03000 8.5e-224 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HICMHLEF_03001 6.4e-60 3.4.23.43
HICMHLEF_03002 6.1e-38 M domain protein
HICMHLEF_03003 0.0 M domain protein
HICMHLEF_03004 2.7e-154 M domain protein
HICMHLEF_03005 8.2e-116 M domain protein
HICMHLEF_03006 3.1e-139 mga K Mga helix-turn-helix domain
HICMHLEF_03007 5.9e-106 mga K Mga helix-turn-helix domain
HICMHLEF_03009 1.7e-63 yjjH S Calcineurin-like phosphoesterase
HICMHLEF_03010 2.3e-38 yjjH S Calcineurin-like phosphoesterase
HICMHLEF_03011 2.6e-256 dtpT U amino acid peptide transporter
HICMHLEF_03012 2.4e-122 macB_3 V ABC transporter, ATP-binding protein
HICMHLEF_03013 1.4e-276 macB_3 V ABC transporter, ATP-binding protein
HICMHLEF_03014 1.4e-65
HICMHLEF_03015 2.1e-73 S function, without similarity to other proteins
HICMHLEF_03016 1.8e-43 G MFS/sugar transport protein
HICMHLEF_03017 1.9e-195 G MFS/sugar transport protein
HICMHLEF_03018 2.9e-175 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
HICMHLEF_03019 5.1e-30 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
HICMHLEF_03020 1e-56
HICMHLEF_03021 7.7e-285 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
HICMHLEF_03022 8.3e-18 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
HICMHLEF_03023 2.7e-24 S Virus attachment protein p12 family
HICMHLEF_03024 1.7e-165 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HICMHLEF_03025 3e-51 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HICMHLEF_03026 4.3e-141 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HICMHLEF_03027 5.2e-99 feoA P FeoA
HICMHLEF_03028 1.4e-117 E lipolytic protein G-D-S-L family
HICMHLEF_03029 3.5e-88 E AAA domain
HICMHLEF_03032 2.9e-119 ywnB S NAD(P)H-binding
HICMHLEF_03033 1.1e-91 S MucBP domain
HICMHLEF_03034 1.3e-85
HICMHLEF_03036 1.2e-68 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HICMHLEF_03037 9.2e-40 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HICMHLEF_03038 4.6e-123 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HICMHLEF_03039 6.2e-173 lacX 5.1.3.3 G Aldose 1-epimerase
HICMHLEF_03040 4.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HICMHLEF_03041 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HICMHLEF_03042 2.2e-271 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HICMHLEF_03043 3.5e-177 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HICMHLEF_03044 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HICMHLEF_03045 4.3e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HICMHLEF_03046 2.5e-169 K LysR substrate binding domain
HICMHLEF_03048 4.3e-158 ppaC 3.6.1.1 C inorganic pyrophosphatase
HICMHLEF_03049 2.9e-207 xerS L Belongs to the 'phage' integrase family
HICMHLEF_03050 0.0 ysaB V FtsX-like permease family
HICMHLEF_03051 2.2e-79 XK27_05695 V ABC transporter, ATP-binding protein
HICMHLEF_03052 1.4e-38 XK27_05695 V ABC transporter, ATP-binding protein
HICMHLEF_03053 3.2e-167 T Histidine kinase-like ATPases
HICMHLEF_03054 3.1e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HICMHLEF_03055 8.6e-09 S Protein of unknown function (DUF4044)
HICMHLEF_03057 7.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HICMHLEF_03058 4.4e-158 ansA 3.5.1.1 EJ Asparaginase
HICMHLEF_03059 1e-107 fat 3.1.2.21 I Acyl-ACP thioesterase
HICMHLEF_03060 2.5e-25 fat 3.1.2.21 I Acyl-ACP thioesterase
HICMHLEF_03061 1.2e-46 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HICMHLEF_03062 6.8e-82 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HICMHLEF_03063 1.7e-57 yabA L Involved in initiation control of chromosome replication
HICMHLEF_03064 1.3e-174 holB 2.7.7.7 L DNA polymerase III
HICMHLEF_03065 7.8e-52 yaaQ S Cyclic-di-AMP receptor
HICMHLEF_03066 2.2e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HICMHLEF_03067 8.7e-38 S Protein of unknown function (DUF2508)
HICMHLEF_03068 3.9e-71 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HICMHLEF_03069 1.5e-33 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HICMHLEF_03070 1.7e-57 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HICMHLEF_03071 3.3e-215 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HICMHLEF_03072 8.9e-87 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HICMHLEF_03073 4.7e-49
HICMHLEF_03074 4.4e-106 rsmC 2.1.1.172 J Methyltransferase
HICMHLEF_03075 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HICMHLEF_03076 1.6e-142 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HICMHLEF_03077 4.7e-70 tnpB L Putative transposase DNA-binding domain
HICMHLEF_03078 3.9e-107 L Transposase and inactivated derivatives, IS30 family
HICMHLEF_03079 3.7e-56 licT K CAT RNA binding domain
HICMHLEF_03080 4.2e-284 cydC V ABC transporter transmembrane region
HICMHLEF_03081 6.1e-310 cydD CO ABC transporter transmembrane region
HICMHLEF_03082 1.7e-75 ynhH S NusG domain II
HICMHLEF_03083 2.8e-170 M Peptidoglycan-binding domain 1 protein
HICMHLEF_03085 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HICMHLEF_03086 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HICMHLEF_03087 2.4e-102 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HICMHLEF_03088 4.2e-29 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HICMHLEF_03089 1.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
HICMHLEF_03090 4.6e-118 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HICMHLEF_03091 1e-73 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HICMHLEF_03092 2e-18 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HICMHLEF_03093 6.5e-174 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HICMHLEF_03094 1.7e-37
HICMHLEF_03095 1.1e-56
HICMHLEF_03096 2.6e-19
HICMHLEF_03097 2.7e-24
HICMHLEF_03098 5.2e-212 L Mga helix-turn-helix domain
HICMHLEF_03099 3.7e-150 yhaI S Protein of unknown function (DUF805)
HICMHLEF_03100 7.4e-55
HICMHLEF_03101 5.8e-234 rarA L recombination factor protein RarA
HICMHLEF_03102 1.2e-216 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HICMHLEF_03103 3.2e-133 K DeoR C terminal sensor domain
HICMHLEF_03104 3.4e-211 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HICMHLEF_03105 2.2e-57 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HICMHLEF_03106 6.4e-162 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HICMHLEF_03107 6.2e-230 sgaT 2.7.1.194 S PTS system sugar-specific permease component
HICMHLEF_03108 1.3e-159 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
HICMHLEF_03109 1e-136 magIII L Base excision DNA repair protein, HhH-GPD family
HICMHLEF_03110 5.7e-248 bmr3 EGP Major facilitator Superfamily
HICMHLEF_03113 3e-89
HICMHLEF_03114 2.2e-216 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HICMHLEF_03115 5.4e-107 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HICMHLEF_03116 2.2e-41 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HICMHLEF_03117 2.2e-96 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HICMHLEF_03118 2.9e-105 hisC 2.6.1.9 E Cys/Met metabolism PLP-dependent enzyme
HICMHLEF_03119 3.3e-52 hisC 2.6.1.9 E Cys/Met metabolism PLP-dependent enzyme
HICMHLEF_03120 7.3e-83 3.6.1.13 L Belongs to the Nudix hydrolase family
HICMHLEF_03121 3.2e-161 degV S EDD domain protein, DegV family
HICMHLEF_03125 6.8e-290 FbpA K Fibronectin-binding protein
HICMHLEF_03126 6.2e-51 S MazG-like family
HICMHLEF_03127 3.2e-193 pfoS S Phosphotransferase system, EIIC
HICMHLEF_03128 2.9e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HICMHLEF_03129 3.6e-95 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HICMHLEF_03130 1e-151 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HICMHLEF_03131 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HICMHLEF_03132 2.7e-26 cspC K Cold shock protein
HICMHLEF_03133 2.4e-26 chpR T PFAM SpoVT AbrB
HICMHLEF_03134 2.3e-81 yvbK 3.1.3.25 K GNAT family
HICMHLEF_03135 1.2e-101 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HICMHLEF_03136 7.9e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HICMHLEF_03137 7.3e-242 pbuX F xanthine permease
HICMHLEF_03138 3e-204 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HICMHLEF_03139 6.4e-163 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HICMHLEF_03140 7.4e-64 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HICMHLEF_03142 1.2e-103
HICMHLEF_03143 4.9e-120
HICMHLEF_03144 5.9e-192 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HICMHLEF_03145 1.2e-110 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HICMHLEF_03146 1.5e-109 vanZ V VanZ like family
HICMHLEF_03147 2.9e-151 glcU U sugar transport
HICMHLEF_03148 3.1e-125 pgi 5.3.1.9 G Belongs to the GPI family
HICMHLEF_03149 4.9e-116 pgi 5.3.1.9 G Belongs to the GPI family
HICMHLEF_03151 5.6e-46 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HICMHLEF_03169 9.4e-66 sigH K Sigma-70 region 2
HICMHLEF_03170 1.1e-297 ybeC E amino acid
HICMHLEF_03171 4.5e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HICMHLEF_03172 1.6e-30 cpoA GT4 M Glycosyltransferase, group 1 family protein
HICMHLEF_03173 1.1e-147 cpoA GT4 M Glycosyltransferase, group 1 family protein
HICMHLEF_03174 7.1e-28 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HICMHLEF_03175 1e-129 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HICMHLEF_03176 1.2e-219 patA 2.6.1.1 E Aminotransferase
HICMHLEF_03177 5.1e-44 ykuJ S Protein of unknown function (DUF1797)
HICMHLEF_03178 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HICMHLEF_03179 1.2e-79 perR P Belongs to the Fur family
HICMHLEF_03180 2.2e-40 nylA 3.5.1.4 J Belongs to the amidase family
HICMHLEF_03181 3.7e-168 nylA 3.5.1.4 J Belongs to the amidase family
HICMHLEF_03182 2.4e-90 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
HICMHLEF_03183 6.1e-86 S ECF transporter, substrate-specific component
HICMHLEF_03184 3.1e-63 S Domain of unknown function (DUF4430)
HICMHLEF_03185 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HICMHLEF_03186 2.5e-39 F nucleoside 2-deoxyribosyltransferase
HICMHLEF_03187 2.9e-159 S Alpha/beta hydrolase of unknown function (DUF915)
HICMHLEF_03188 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
HICMHLEF_03189 5.7e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HICMHLEF_03190 2.7e-169 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HICMHLEF_03191 1.1e-164 menA 2.5.1.74 M UbiA prenyltransferase family
HICMHLEF_03193 5.4e-195 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HICMHLEF_03194 3.3e-42 tnpB L Putative transposase DNA-binding domain
HICMHLEF_03195 3.8e-148 P Belongs to the nlpA lipoprotein family
HICMHLEF_03196 2.9e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HICMHLEF_03197 5.8e-08 metI P ABC transporter permease
HICMHLEF_03198 1.9e-85 metI P ABC transporter permease
HICMHLEF_03199 1.9e-141 sufC O FeS assembly ATPase SufC
HICMHLEF_03200 3.3e-172 sufD O FeS assembly protein SufD
HICMHLEF_03201 5.8e-222 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HICMHLEF_03202 5.1e-47 nifU C SUF system FeS assembly protein, NifU family
HICMHLEF_03203 1.2e-279 sufB O assembly protein SufB
HICMHLEF_03205 1.8e-26
HICMHLEF_03206 1.1e-65 yueI S Protein of unknown function (DUF1694)
HICMHLEF_03207 2e-164 S Protein of unknown function (DUF2785)
HICMHLEF_03208 4.4e-158 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HICMHLEF_03209 1e-156 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HICMHLEF_03210 7.2e-124 citR K FCD
HICMHLEF_03211 3.8e-265 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
HICMHLEF_03212 5.2e-101 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HICMHLEF_03213 9.8e-283 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HICMHLEF_03214 2.6e-155 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HICMHLEF_03215 2.2e-48 citD C Covalent carrier of the coenzyme of citrate lyase
HICMHLEF_03216 2.4e-63 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HICMHLEF_03217 2.8e-103 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HICMHLEF_03219 1.7e-97 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
HICMHLEF_03220 1.2e-22 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
HICMHLEF_03221 6e-59 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
HICMHLEF_03222 8.7e-37 gcdC 2.3.1.12 I Biotin-requiring enzyme
HICMHLEF_03223 3.8e-51
HICMHLEF_03224 1.5e-39 citM C Citrate transporter
HICMHLEF_03225 4e-151 citM C Citrate transporter
HICMHLEF_03226 2.8e-23 citM C Citrate transporter
HICMHLEF_03227 1.7e-128 trmK 2.1.1.217 S SAM-dependent methyltransferase
HICMHLEF_03228 4.4e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HICMHLEF_03229 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HICMHLEF_03230 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HICMHLEF_03231 1.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HICMHLEF_03232 3.7e-38 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
HICMHLEF_03233 1.1e-30 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
HICMHLEF_03235 1.7e-97 V ATPases associated with a variety of cellular activities
HICMHLEF_03236 3.9e-53
HICMHLEF_03237 6.4e-38 S Abortive infection C-terminus
HICMHLEF_03239 2.1e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HICMHLEF_03240 7.3e-114 coaA 2.7.1.33 F Pantothenic acid kinase
HICMHLEF_03241 6.6e-15 coaA 2.7.1.33 F Pantothenic acid kinase
HICMHLEF_03242 4.4e-53
HICMHLEF_03243 2.4e-41
HICMHLEF_03244 2.4e-101 pipD E Dipeptidase
HICMHLEF_03245 8.1e-102 pipD E Dipeptidase
HICMHLEF_03246 1.2e-82 ykhA 3.1.2.20 I Thioesterase superfamily
HICMHLEF_03247 0.0 helD 3.6.4.12 L DNA helicase
HICMHLEF_03248 1.2e-158 recN L May be involved in recombinational repair of damaged DNA
HICMHLEF_03249 2e-74 argR K Regulates arginine biosynthesis genes
HICMHLEF_03250 5.2e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HICMHLEF_03251 5.3e-128 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HICMHLEF_03253 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HICMHLEF_03254 2.1e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HICMHLEF_03255 5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HICMHLEF_03256 2e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HICMHLEF_03257 1.5e-72 yqhY S Asp23 family, cell envelope-related function
HICMHLEF_03258 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HICMHLEF_03259 7e-203 ypdF 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HICMHLEF_03260 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HICMHLEF_03261 1.2e-55 ysxB J Cysteine protease Prp
HICMHLEF_03262 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HICMHLEF_03263 3.8e-32
HICMHLEF_03264 2.5e-74 ytxK 2.1.1.72 L N-6 DNA Methylase
HICMHLEF_03265 1.3e-73
HICMHLEF_03266 1.2e-247 cycA E Amino acid permease
HICMHLEF_03267 5.8e-143 arbV 2.3.1.51 I Phosphate acyltransferases
HICMHLEF_03268 2.1e-162 arbx M Glycosyl transferase family 8
HICMHLEF_03269 9.9e-135 arbY M family 8
HICMHLEF_03270 2.9e-162 arbZ I Phosphate acyltransferases
HICMHLEF_03271 0.0 rafA 3.2.1.22 G alpha-galactosidase
HICMHLEF_03272 6.7e-96 sip L Belongs to the 'phage' integrase family
HICMHLEF_03273 1.1e-217 EGP Transmembrane secretion effector
HICMHLEF_03274 7.1e-68 msi198 K Acetyltransferase (GNAT) domain
HICMHLEF_03275 5.9e-70 K Acetyltransferase (GNAT) domain
HICMHLEF_03276 2.6e-112 nfnB 1.5.1.34 C Nitroreductase family
HICMHLEF_03277 1.3e-145 Q Fumarylacetoacetate (FAA) hydrolase family
HICMHLEF_03278 3.1e-206 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HICMHLEF_03279 2.6e-15 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HICMHLEF_03280 1.3e-43 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HICMHLEF_03281 3.2e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HICMHLEF_03282 4.8e-114 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HICMHLEF_03283 6.8e-99 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HICMHLEF_03284 2.4e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HICMHLEF_03285 6.8e-212 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HICMHLEF_03286 1.2e-299 frvR K Mga helix-turn-helix domain
HICMHLEF_03287 8.2e-89 frvR K Mga helix-turn-helix domain
HICMHLEF_03288 4.6e-48 frvR K Mga helix-turn-helix domain
HICMHLEF_03289 3.5e-67 frvR K Mga helix-turn-helix domain
HICMHLEF_03290 2.6e-189 lysP E amino acid
HICMHLEF_03291 2e-68 lysP E amino acid
HICMHLEF_03292 3.3e-07 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HICMHLEF_03294 8.9e-107 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HICMHLEF_03295 6.6e-125 gntR1 K UbiC transcription regulator-associated domain protein
HICMHLEF_03296 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HICMHLEF_03297 2.2e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HICMHLEF_03298 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
HICMHLEF_03299 7.3e-40 sprD D Domain of Unknown Function (DUF1542)
HICMHLEF_03300 7.1e-21 sprD D Domain of Unknown Function (DUF1542)
HICMHLEF_03301 1.8e-120 tagF 2.7.8.12 M Glycosyltransferase like family 2
HICMHLEF_03302 2.4e-196 S Bacterial membrane protein, YfhO
HICMHLEF_03303 2.4e-300 M Glycosyl hydrolases family 25
HICMHLEF_03304 2.8e-163 M Dolichyl-phosphate-mannose-protein mannosyltransferase
HICMHLEF_03306 9.5e-189 S Bacterial protein of unknown function (DUF916)
HICMHLEF_03307 8.4e-102
HICMHLEF_03308 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HICMHLEF_03309 2.3e-159 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HICMHLEF_03310 1.7e-156 I alpha/beta hydrolase fold
HICMHLEF_03311 1.3e-47
HICMHLEF_03312 6.5e-69
HICMHLEF_03313 7.9e-46
HICMHLEF_03315 2.3e-95 repE K Primase C terminal 1 (PriCT-1)
HICMHLEF_03316 1.7e-101 D CobQ CobB MinD ParA nucleotide binding domain protein
HICMHLEF_03318 1.4e-69 tnp L DDE domain
HICMHLEF_03319 4.2e-41 tnp L DDE domain
HICMHLEF_03320 5.4e-45 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HICMHLEF_03321 7.5e-115 L Resolvase, N terminal domain
HICMHLEF_03322 3.2e-46 ligA 6.5.1.2 L BRCA1 C Terminus (BRCT) domain
HICMHLEF_03323 1.8e-162 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HICMHLEF_03324 3e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HICMHLEF_03325 1.7e-12
HICMHLEF_03326 6.4e-32 ywzB S Protein of unknown function (DUF1146)
HICMHLEF_03327 2.5e-44 mbl D Cell shape determining protein MreB Mrl
HICMHLEF_03328 1.2e-123 mbl D Cell shape determining protein MreB Mrl
HICMHLEF_03329 1.5e-16 epuA S DNA-directed RNA polymerase subunit beta
HICMHLEF_03330 2.1e-54 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HICMHLEF_03331 2.8e-29 S Protein of unknown function (DUF2969)
HICMHLEF_03332 1.3e-45 rodA D Belongs to the SEDS family
HICMHLEF_03333 5.6e-60 rodA D Belongs to the SEDS family
HICMHLEF_03334 5.7e-80 rodA D Belongs to the SEDS family
HICMHLEF_03335 1.1e-47 gcvH E glycine cleavage
HICMHLEF_03336 4.1e-77 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HICMHLEF_03337 2.2e-68 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HICMHLEF_03338 5.7e-228 yfmL 3.6.4.13 L DEAD DEAH box helicase
HICMHLEF_03339 6.8e-48 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HICMHLEF_03340 3.3e-71 S Domain of unknown function (DUF3284)
HICMHLEF_03344 2.2e-229 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HICMHLEF_03345 5.2e-102 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HICMHLEF_03346 3.1e-223 pepS E Thermophilic metalloprotease (M29)
HICMHLEF_03347 1.7e-22 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HICMHLEF_03348 1.4e-147 dprA LU DNA protecting protein DprA
HICMHLEF_03349 1.9e-21 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HICMHLEF_03350 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HICMHLEF_03351 1.1e-92 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HICMHLEF_03352 1e-125 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HICMHLEF_03353 1.5e-166 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HICMHLEF_03354 5.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HICMHLEF_03355 1.2e-178 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HICMHLEF_03357 2.5e-90 L COG1484 DNA replication protein
HICMHLEF_03358 8.8e-170 L Integrase core domain
HICMHLEF_03359 6.3e-40 L Transposase and inactivated derivatives
HICMHLEF_03360 1.9e-39 2.4.1.315 GT2 M Glycosyltransferase like family 2
HICMHLEF_03361 3.6e-29 cps2J S Polysaccharide biosynthesis protein
HICMHLEF_03362 3.8e-30 cps2J S Polysaccharide biosynthesis protein
HICMHLEF_03363 2.4e-29 2.4.1.166 GT2 M Glycosyltransferase like family 2
HICMHLEF_03364 1e-104 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HICMHLEF_03365 2.5e-72 epsB M biosynthesis protein
HICMHLEF_03366 5.6e-39 epsB M biosynthesis protein
HICMHLEF_03367 3.9e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HICMHLEF_03368 2.5e-239 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HICMHLEF_03369 2.8e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HICMHLEF_03370 2.6e-236 pyrP F Permease
HICMHLEF_03371 1.4e-71 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HICMHLEF_03372 4.3e-155 L hmm pf00665
HICMHLEF_03373 1.4e-58 L Helix-turn-helix domain
HICMHLEF_03374 3.2e-71 V Beta-lactamase
HICMHLEF_03375 1.3e-90 V Beta-lactamase
HICMHLEF_03376 1.4e-21 V Beta-lactamase
HICMHLEF_03377 3.7e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HICMHLEF_03378 1.3e-221 V Beta-lactamase
HICMHLEF_03379 3.1e-139 mga K Mga helix-turn-helix domain
HICMHLEF_03380 3.4e-152 sprD D Domain of Unknown Function (DUF1542)
HICMHLEF_03381 1.3e-42 sprD D Domain of Unknown Function (DUF1542)
HICMHLEF_03382 3.2e-07 sprD D Domain of Unknown Function (DUF1542)
HICMHLEF_03383 5.5e-53 V (ABC) transporter
HICMHLEF_03384 2.9e-158 V (ABC) transporter
HICMHLEF_03385 8.4e-224 V ABC transporter transmembrane region
HICMHLEF_03386 6.4e-72 V ABC transporter transmembrane region
HICMHLEF_03387 2.3e-47 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HICMHLEF_03388 7.9e-155 ecsB U ABC transporter
HICMHLEF_03389 2.1e-43 ecsB U ABC transporter
HICMHLEF_03390 1.2e-62 ecsA V ABC transporter, ATP-binding protein
HICMHLEF_03391 8e-61 ecsA V ABC transporter, ATP-binding protein
HICMHLEF_03392 1.4e-58 hit FG histidine triad
HICMHLEF_03393 1.3e-11 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HICMHLEF_03394 3.4e-20 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HICMHLEF_03395 3.7e-91 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HICMHLEF_03396 1.6e-94 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HICMHLEF_03397 6e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HICMHLEF_03398 1.4e-81 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HICMHLEF_03399 3.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HICMHLEF_03400 1.2e-12 dnaB L replication initiation and membrane attachment
HICMHLEF_03404 4.8e-131 S Domain of unknown function (DUF4918)
HICMHLEF_03405 5.5e-51 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HICMHLEF_03406 6.8e-129 S Uncharacterized protein conserved in bacteria (DUF2252)
HICMHLEF_03407 3.2e-98 S Uncharacterized protein conserved in bacteria (DUF2252)
HICMHLEF_03408 1.7e-179 yihY S Belongs to the UPF0761 family
HICMHLEF_03409 1.9e-80 fld C Flavodoxin
HICMHLEF_03410 1.1e-43
HICMHLEF_03411 3.2e-60
HICMHLEF_03412 4.6e-14
HICMHLEF_03414 2.2e-156 L Bifunctional DNA primase/polymerase, N-terminal
HICMHLEF_03415 2.7e-199 S Virulence-associated protein E
HICMHLEF_03416 8e-229 wbbX GT2,GT4 M Glycosyl transferases group 1
HICMHLEF_03417 1.8e-31 yttA 2.7.13.3 S Pfam Transposase IS66
HICMHLEF_03418 5.1e-45 F DNA/RNA non-specific endonuclease
HICMHLEF_03419 3.1e-43 F DNA/RNA non-specific endonuclease
HICMHLEF_03422 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HICMHLEF_03423 1.9e-42 sprD D Domain of Unknown Function (DUF1542)
HICMHLEF_03424 2.4e-72 dnaB L replication initiation and membrane attachment
HICMHLEF_03425 1.2e-169 dnaI L Primosomal protein DnaI
HICMHLEF_03427 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HICMHLEF_03430 6.1e-63 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HICMHLEF_03431 1.1e-24 sprD D Domain of Unknown Function (DUF1542)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)