ORF_ID e_value Gene_name EC_number CAZy COGs Description
DOFPDPNE_00001 3.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOFPDPNE_00002 5.1e-246 nhaC C Na H antiporter NhaC
DOFPDPNE_00003 1.4e-27
DOFPDPNE_00004 4.9e-120 ybhL S Belongs to the BI1 family
DOFPDPNE_00005 3.6e-115 S Protein of unknown function (DUF1211)
DOFPDPNE_00006 1e-170 yegS 2.7.1.107 G Lipid kinase
DOFPDPNE_00007 2.9e-276 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOFPDPNE_00008 7.6e-261 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DOFPDPNE_00009 5.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOFPDPNE_00010 4.4e-211 camS S sex pheromone
DOFPDPNE_00011 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DOFPDPNE_00012 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DOFPDPNE_00013 1.6e-104 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
DOFPDPNE_00015 4.8e-87 ydcK S Belongs to the SprT family
DOFPDPNE_00016 9.7e-137 M Glycosyltransferase sugar-binding region containing DXD motif
DOFPDPNE_00017 3.1e-262 epsU S Polysaccharide biosynthesis protein
DOFPDPNE_00018 5.9e-227 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DOFPDPNE_00019 1.7e-168 pacL 3.6.3.8 P P-type ATPase
DOFPDPNE_00020 2.2e-117 pacL 3.6.3.8 P P-type ATPase
DOFPDPNE_00021 4.5e-77 pacL 3.6.3.8 P P-type ATPase
DOFPDPNE_00022 4.9e-57 pacL 3.6.3.8 P P-type ATPase
DOFPDPNE_00023 3.1e-84 yjeM E Amino Acid
DOFPDPNE_00024 6.6e-179 yjeM E Amino Acid
DOFPDPNE_00025 4.6e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DOFPDPNE_00026 1.1e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
DOFPDPNE_00027 1.7e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DOFPDPNE_00028 3.6e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DOFPDPNE_00029 9.5e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DOFPDPNE_00030 4.9e-176 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOFPDPNE_00031 1.8e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DOFPDPNE_00032 7.1e-217 aspC 2.6.1.1 E Aminotransferase
DOFPDPNE_00033 1.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DOFPDPNE_00034 1.1e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DOFPDPNE_00035 3.5e-54 trxA O Belongs to the thioredoxin family
DOFPDPNE_00036 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DOFPDPNE_00037 8.1e-51 yrzB S Belongs to the UPF0473 family
DOFPDPNE_00038 4.7e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DOFPDPNE_00039 2e-42 yrzL S Belongs to the UPF0297 family
DOFPDPNE_00040 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DOFPDPNE_00041 9.9e-88
DOFPDPNE_00042 4.8e-44
DOFPDPNE_00043 3.3e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DOFPDPNE_00044 2.5e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
DOFPDPNE_00045 7.1e-214 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DOFPDPNE_00046 1.9e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DOFPDPNE_00047 7.5e-39 yajC U Preprotein translocase
DOFPDPNE_00048 7.9e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DOFPDPNE_00049 3.5e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DOFPDPNE_00050 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DOFPDPNE_00051 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DOFPDPNE_00052 2.9e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DOFPDPNE_00053 3.9e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DOFPDPNE_00054 3.9e-90
DOFPDPNE_00055 1.3e-45
DOFPDPNE_00056 6.1e-91 2.7.1.199, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DOFPDPNE_00057 1.8e-31 scrR K Transcriptional regulator, LacI family
DOFPDPNE_00058 1.9e-118 scrR K Transcriptional regulator, LacI family
DOFPDPNE_00059 8.5e-123 liaI S membrane
DOFPDPNE_00060 6.7e-78 XK27_02470 K LytTr DNA-binding domain
DOFPDPNE_00061 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DOFPDPNE_00062 0.0 uup S ABC transporter, ATP-binding protein
DOFPDPNE_00063 3.8e-148
DOFPDPNE_00064 1.5e-169 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
DOFPDPNE_00065 0.0 S membrane
DOFPDPNE_00066 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
DOFPDPNE_00067 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DOFPDPNE_00068 1.7e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DOFPDPNE_00069 6.8e-119 gluP 3.4.21.105 S Rhomboid family
DOFPDPNE_00070 3.3e-33 yqgQ S Bacterial protein of unknown function (DUF910)
DOFPDPNE_00071 4.5e-70 yqhL P Rhodanese-like protein
DOFPDPNE_00072 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DOFPDPNE_00073 2.1e-31 S Archaea bacterial proteins of unknown function
DOFPDPNE_00074 4.4e-92 M NlpC/P60 family
DOFPDPNE_00075 1.2e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
DOFPDPNE_00076 9.6e-25
DOFPDPNE_00077 7.2e-278 S O-antigen ligase like membrane protein
DOFPDPNE_00078 5.6e-95
DOFPDPNE_00079 0.0 pepO 3.4.24.71 O Peptidase family M13
DOFPDPNE_00080 1e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
DOFPDPNE_00081 4.1e-115 plsC 2.3.1.51 I Acyltransferase
DOFPDPNE_00082 2.5e-197 yabB 2.1.1.223 L Methyltransferase small domain
DOFPDPNE_00083 1.6e-140 rpsB J Belongs to the universal ribosomal protein uS2 family
DOFPDPNE_00084 6.3e-185 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DOFPDPNE_00085 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DOFPDPNE_00086 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DOFPDPNE_00087 3.5e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DOFPDPNE_00088 1.6e-146 cdsA 2.7.7.41 I Belongs to the CDS family
DOFPDPNE_00089 5.2e-197 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
DOFPDPNE_00090 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DOFPDPNE_00091 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOFPDPNE_00092 3.2e-83 rimP J Required for maturation of 30S ribosomal subunits
DOFPDPNE_00093 2.9e-197 nusA K Participates in both transcription termination and antitermination
DOFPDPNE_00094 3e-47 ylxR K Protein of unknown function (DUF448)
DOFPDPNE_00095 1.2e-46 rplGA J ribosomal protein
DOFPDPNE_00096 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DOFPDPNE_00097 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DOFPDPNE_00098 2.6e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DOFPDPNE_00099 3.3e-183 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DOFPDPNE_00100 4.5e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DOFPDPNE_00101 9.7e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DOFPDPNE_00102 0.0 dnaK O Heat shock 70 kDa protein
DOFPDPNE_00103 7.6e-203 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DOFPDPNE_00104 0.0 clpE O Belongs to the ClpA ClpB family
DOFPDPNE_00105 3.9e-44 XK27_09445 S Domain of unknown function (DUF1827)
DOFPDPNE_00106 3.2e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DOFPDPNE_00107 7.8e-160 hlyX S Transporter associated domain
DOFPDPNE_00108 1.1e-72
DOFPDPNE_00109 1.9e-86
DOFPDPNE_00110 2.1e-146 recX 2.4.1.337 GT4 S Regulatory protein RecX
DOFPDPNE_00111 3.9e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOFPDPNE_00112 1.1e-46 tnpR1 L Resolvase, N terminal domain
DOFPDPNE_00113 4.8e-52 tnpR1 L Resolvase, N terminal domain
DOFPDPNE_00114 2.7e-17
DOFPDPNE_00116 1.7e-36
DOFPDPNE_00117 1.4e-20 S DNA primase
DOFPDPNE_00120 2.5e-67 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DOFPDPNE_00121 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DOFPDPNE_00122 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DOFPDPNE_00123 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DOFPDPNE_00124 5.3e-82 S Short repeat of unknown function (DUF308)
DOFPDPNE_00125 1.4e-164 rapZ S Displays ATPase and GTPase activities
DOFPDPNE_00126 4.4e-194 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DOFPDPNE_00127 1.1e-170 whiA K May be required for sporulation
DOFPDPNE_00128 6e-123 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DOFPDPNE_00129 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DOFPDPNE_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DOFPDPNE_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DOFPDPNE_00132 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
DOFPDPNE_00133 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DOFPDPNE_00134 1.7e-105 rplD J Forms part of the polypeptide exit tunnel
DOFPDPNE_00135 4.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DOFPDPNE_00136 4.7e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DOFPDPNE_00137 4.2e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DOFPDPNE_00138 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DOFPDPNE_00139 1.5e-110 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DOFPDPNE_00140 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DOFPDPNE_00141 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
DOFPDPNE_00142 1.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DOFPDPNE_00143 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DOFPDPNE_00144 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DOFPDPNE_00145 3.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DOFPDPNE_00146 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DOFPDPNE_00147 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DOFPDPNE_00148 2.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DOFPDPNE_00149 2.8e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DOFPDPNE_00150 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DOFPDPNE_00151 2.3e-24 rpmD J Ribosomal protein L30
DOFPDPNE_00152 1.5e-71 rplO J Binds to the 23S rRNA
DOFPDPNE_00153 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DOFPDPNE_00154 2.7e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DOFPDPNE_00155 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DOFPDPNE_00156 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DOFPDPNE_00157 3.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DOFPDPNE_00158 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DOFPDPNE_00159 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOFPDPNE_00160 1.4e-60 rplQ J Ribosomal protein L17
DOFPDPNE_00161 1.1e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOFPDPNE_00162 9.5e-152 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOFPDPNE_00163 5.1e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOFPDPNE_00164 4.6e-151 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DOFPDPNE_00165 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DOFPDPNE_00166 1.6e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
DOFPDPNE_00167 2.6e-162 2.7.7.12 C Domain of unknown function (DUF4931)
DOFPDPNE_00168 9.2e-167 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOFPDPNE_00169 5.3e-127 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DOFPDPNE_00170 0.0 kup P Transport of potassium into the cell
DOFPDPNE_00171 4.8e-176 rihB 3.2.2.1 F Nucleoside
DOFPDPNE_00172 2.2e-20 gntR K UbiC transcription regulator-associated domain protein
DOFPDPNE_00173 1.9e-74 gntR K UbiC transcription regulator-associated domain protein
DOFPDPNE_00175 8.4e-290 clcA P chloride
DOFPDPNE_00176 8.5e-212
DOFPDPNE_00177 1.2e-18
DOFPDPNE_00178 4.5e-156 EGP Sugar (and other) transporter
DOFPDPNE_00179 1.7e-21 EGP Sugar (and other) transporter
DOFPDPNE_00180 0.0 copA 3.6.3.54 P P-type ATPase
DOFPDPNE_00181 1.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
DOFPDPNE_00182 3.5e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
DOFPDPNE_00183 9.3e-77 atkY K Penicillinase repressor
DOFPDPNE_00184 2.3e-35
DOFPDPNE_00185 5.5e-226 pbuG S permease
DOFPDPNE_00186 5.5e-272 pepV 3.5.1.18 E dipeptidase PepV
DOFPDPNE_00187 2.3e-170 V Beta-lactamase
DOFPDPNE_00188 3.4e-29 L IS1381, transposase OrfA
DOFPDPNE_00189 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DOFPDPNE_00190 2.1e-282
DOFPDPNE_00191 3.2e-89 XK27_09675 K Acetyltransferase (GNAT) domain
DOFPDPNE_00192 1.5e-52 S Protein of unknown function (DUF3021)
DOFPDPNE_00193 1.6e-76 K LytTr DNA-binding domain
DOFPDPNE_00194 7.2e-43
DOFPDPNE_00195 5.9e-92 L COG2826 Transposase and inactivated derivatives, IS30 family
DOFPDPNE_00196 2.9e-116 G phosphoglycerate mutase
DOFPDPNE_00197 9.9e-216 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DOFPDPNE_00198 7.9e-216 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFPDPNE_00199 8.5e-48 sugE U Multidrug resistance protein
DOFPDPNE_00200 4.4e-29 3.6.1.13 L Belongs to the Nudix hydrolase family
DOFPDPNE_00201 3.3e-83 L PFAM transposase, IS4 family protein
DOFPDPNE_00202 6.4e-42 L PFAM transposase, IS4 family protein
DOFPDPNE_00203 9.6e-138 XK27_08845 S ABC transporter, ATP-binding protein
DOFPDPNE_00204 1.7e-125 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
DOFPDPNE_00205 8e-177 ABC-SBP S ABC transporter
DOFPDPNE_00206 1.5e-137 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DOFPDPNE_00207 6.7e-93 S SLAP domain
DOFPDPNE_00208 2.4e-59 S SLAP domain
DOFPDPNE_00209 3.6e-165 yvgN C Aldo keto reductase
DOFPDPNE_00210 0.0 tetP J elongation factor G
DOFPDPNE_00211 5e-60 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
DOFPDPNE_00212 6.3e-20 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
DOFPDPNE_00213 4e-43 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
DOFPDPNE_00214 3.1e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFPDPNE_00215 1.4e-169 yniA G Phosphotransferase enzyme family
DOFPDPNE_00216 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
DOFPDPNE_00217 2e-138 E amino acid
DOFPDPNE_00218 0.0 L Helicase C-terminal domain protein
DOFPDPNE_00219 4.6e-196 pbpX1 V Beta-lactamase
DOFPDPNE_00220 3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DOFPDPNE_00221 7e-147
DOFPDPNE_00222 2.8e-25 L PFAM transposase, IS4 family protein
DOFPDPNE_00223 2.4e-38 L PFAM transposase, IS4 family protein
DOFPDPNE_00224 1.6e-27 L Transposase
DOFPDPNE_00225 3.8e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DOFPDPNE_00226 7.2e-42 K Helix-turn-helix XRE-family like proteins
DOFPDPNE_00227 2.2e-54
DOFPDPNE_00228 5.2e-55 L Transposase
DOFPDPNE_00229 1.5e-144 L Transposase
DOFPDPNE_00230 9.9e-55 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DOFPDPNE_00231 9.3e-138 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DOFPDPNE_00232 3.1e-66 2.4.1.83 GT2 S GtrA-like protein
DOFPDPNE_00233 9.5e-172 yfdH GT2 M Glycosyltransferase like family 2
DOFPDPNE_00234 1.2e-244 L transposase, IS605 OrfB family
DOFPDPNE_00235 2.4e-36
DOFPDPNE_00236 1e-124 magIII L Base excision DNA repair protein, HhH-GPD family
DOFPDPNE_00237 6.5e-57 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DOFPDPNE_00238 3e-201 folE 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 F GTP cyclohydrolase 1
DOFPDPNE_00239 3.6e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DOFPDPNE_00240 1e-201 folP 2.5.1.15 H dihydropteroate synthase
DOFPDPNE_00241 3.1e-98 3.6.1.55, 3.6.1.67 F NUDIX domain
DOFPDPNE_00242 6e-61 adhR K helix_turn_helix, mercury resistance
DOFPDPNE_00243 1e-111 papP P ABC transporter, permease protein
DOFPDPNE_00244 4e-79 P ABC transporter permease
DOFPDPNE_00245 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOFPDPNE_00246 9.1e-161 cjaA ET ABC transporter substrate-binding protein
DOFPDPNE_00247 3.3e-48 L Helix-turn-helix domain
DOFPDPNE_00248 4.2e-197 L hmm pf00665
DOFPDPNE_00249 1.7e-90 dam 2.1.1.72 H Site-specific DNA-methyltransferase (adenine-specific)
DOFPDPNE_00251 1.3e-116 L Integrase
DOFPDPNE_00253 2.6e-255 gor 1.8.1.7 C Glutathione reductase
DOFPDPNE_00254 7.4e-61 K Acetyltransferase (GNAT) family
DOFPDPNE_00255 1e-57 S Alpha beta hydrolase
DOFPDPNE_00256 6.1e-18 S Hydrolases of the alpha beta superfamily
DOFPDPNE_00257 2.1e-39 S Hydrolases of the alpha beta superfamily
DOFPDPNE_00258 1.7e-142 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DOFPDPNE_00259 8.8e-29 1.1.1.3 T phosphoserine phosphatase activity
DOFPDPNE_00260 1.9e-09 1.1.1.3 T phosphoserine phosphatase activity
DOFPDPNE_00261 1.4e-107 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DOFPDPNE_00262 9.5e-94 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DOFPDPNE_00263 9.4e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
DOFPDPNE_00264 7.6e-94 K acetyltransferase
DOFPDPNE_00265 1.2e-85 dps P Belongs to the Dps family
DOFPDPNE_00266 3.5e-209 snf 2.7.11.1 KL domain protein
DOFPDPNE_00267 6.5e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DOFPDPNE_00268 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOFPDPNE_00269 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOFPDPNE_00270 2.4e-170 K Transcriptional regulator
DOFPDPNE_00271 1.5e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
DOFPDPNE_00272 5.9e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOFPDPNE_00273 1.8e-54 K Helix-turn-helix domain
DOFPDPNE_00274 5.6e-104 yoaK S Protein of unknown function (DUF1275)
DOFPDPNE_00275 2.7e-33 S Transglycosylase associated protein
DOFPDPNE_00276 2.3e-25 lysA2 M Glycosyl hydrolases family 25
DOFPDPNE_00277 2.5e-44 M Glycosyl hydrolases family 25
DOFPDPNE_00278 3.5e-26 M Glycosyl hydrolases family 25
DOFPDPNE_00279 2.4e-46
DOFPDPNE_00280 1.2e-109 XK27_00160 S Domain of unknown function (DUF5052)
DOFPDPNE_00281 4.3e-91 adk 2.7.4.3 F topology modulation protein
DOFPDPNE_00282 1.9e-80
DOFPDPNE_00283 7.6e-205 xerS L Belongs to the 'phage' integrase family
DOFPDPNE_00284 7.3e-80 degV S EDD domain protein, DegV family
DOFPDPNE_00285 5.4e-69 degV S EDD domain protein, DegV family
DOFPDPNE_00286 4.4e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOFPDPNE_00287 7.4e-74 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DOFPDPNE_00288 3.5e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOFPDPNE_00289 3.6e-94 sigH K Belongs to the sigma-70 factor family
DOFPDPNE_00290 2.8e-34
DOFPDPNE_00291 6.6e-284 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
DOFPDPNE_00292 6.4e-88 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOFPDPNE_00293 2.1e-48 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOFPDPNE_00294 2e-49 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOFPDPNE_00295 1.3e-96 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOFPDPNE_00296 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DOFPDPNE_00297 8.1e-102 nusG K Participates in transcription elongation, termination and antitermination
DOFPDPNE_00298 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DOFPDPNE_00299 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DOFPDPNE_00300 4.1e-26
DOFPDPNE_00301 2.5e-40 ptsH G phosphocarrier protein HPR
DOFPDPNE_00302 1.9e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOFPDPNE_00303 7.9e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DOFPDPNE_00304 1.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DOFPDPNE_00305 2.7e-160 coiA 3.6.4.12 S Competence protein
DOFPDPNE_00306 1e-113 yjbH Q Thioredoxin
DOFPDPNE_00307 2.3e-113 yjbK S CYTH
DOFPDPNE_00308 2.1e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
DOFPDPNE_00309 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOFPDPNE_00310 3.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOFPDPNE_00311 2.9e-31 mycA 4.2.1.53 S Myosin-crossreactive antigen
DOFPDPNE_00312 5.2e-203 mycA 4.2.1.53 S Myosin-crossreactive antigen
DOFPDPNE_00313 2.7e-58 mycA 4.2.1.53 S Myosin-crossreactive antigen
DOFPDPNE_00314 3.5e-110 S SNARE associated Golgi protein
DOFPDPNE_00315 8.8e-203 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
DOFPDPNE_00317 3.9e-33
DOFPDPNE_00318 2.1e-39
DOFPDPNE_00319 1.2e-91 3.6.1.55 L NUDIX domain
DOFPDPNE_00320 3.5e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
DOFPDPNE_00321 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DOFPDPNE_00323 2.5e-112 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DOFPDPNE_00324 4.8e-34 padC Q Phenolic acid decarboxylase
DOFPDPNE_00325 5e-93 padR K Virulence activator alpha C-term
DOFPDPNE_00326 4.4e-110 M ErfK YbiS YcfS YnhG
DOFPDPNE_00327 5.6e-155 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DOFPDPNE_00328 5.8e-244 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DOFPDPNE_00330 2e-49 pspC KT PspC domain
DOFPDPNE_00331 2.5e-49 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
DOFPDPNE_00332 3.5e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DOFPDPNE_00333 1.7e-29 frnE Q DSBA-like thioredoxin domain
DOFPDPNE_00334 3.5e-18 frnE Q DSBA-like thioredoxin domain
DOFPDPNE_00335 1.7e-10 frnE Q DSBA-like thioredoxin domain
DOFPDPNE_00336 3.1e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DOFPDPNE_00337 7.2e-118 M1-798 K Rhodanese Homology Domain
DOFPDPNE_00338 1.4e-59 CO Thioredoxin
DOFPDPNE_00339 5.6e-21
DOFPDPNE_00340 1.3e-40 UW LPXTG-motif cell wall anchor domain protein
DOFPDPNE_00341 2.5e-35 infB UW LPXTG-motif cell wall anchor domain protein
DOFPDPNE_00342 3.2e-64 O Belongs to the peptidase S8 family
DOFPDPNE_00343 4.9e-88 O Belongs to the peptidase S8 family
DOFPDPNE_00344 1.5e-20 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
DOFPDPNE_00345 2e-297 ytgP S Polysaccharide biosynthesis protein
DOFPDPNE_00346 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOFPDPNE_00347 6e-120 3.6.1.27 I Acid phosphatase homologues
DOFPDPNE_00348 2.7e-62 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DOFPDPNE_00349 3.1e-72 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DOFPDPNE_00350 4.4e-264 qacA EGP Major facilitator Superfamily
DOFPDPNE_00351 2.5e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DOFPDPNE_00354 4.2e-169 psaA P Belongs to the bacterial solute-binding protein 9 family
DOFPDPNE_00357 1.2e-155 glcU U sugar transport
DOFPDPNE_00358 6e-73 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DOFPDPNE_00359 6.1e-130 L Transposase
DOFPDPNE_00360 5.5e-101 L Resolvase, N terminal domain
DOFPDPNE_00361 1.8e-13 ytgB S Transglycosylase associated protein
DOFPDPNE_00362 2.8e-174 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
DOFPDPNE_00363 3.8e-78 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DOFPDPNE_00364 9.6e-80 marR K Transcriptional regulator
DOFPDPNE_00365 4.5e-180 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOFPDPNE_00366 1.4e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOFPDPNE_00367 2e-169 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
DOFPDPNE_00368 3.9e-128 IQ reductase
DOFPDPNE_00369 2.7e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DOFPDPNE_00370 3.7e-79 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DOFPDPNE_00371 2.7e-73 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
DOFPDPNE_00372 2.5e-261 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
DOFPDPNE_00373 3.5e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DOFPDPNE_00374 3.1e-144 accA 2.1.3.15, 6.4.1.2 I alpha subunit
DOFPDPNE_00375 9.9e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
DOFPDPNE_00376 1.4e-189 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DOFPDPNE_00377 6.3e-91 bioY S BioY family
DOFPDPNE_00378 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOFPDPNE_00379 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOFPDPNE_00380 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DOFPDPNE_00381 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
DOFPDPNE_00383 1.6e-08
DOFPDPNE_00384 3.7e-27
DOFPDPNE_00386 5.8e-299 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DOFPDPNE_00387 8e-196 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOFPDPNE_00388 3.1e-164 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DOFPDPNE_00389 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOFPDPNE_00390 1.2e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DOFPDPNE_00391 7.7e-61 yabR J S1 RNA binding domain
DOFPDPNE_00392 2.6e-59 divIC D Septum formation initiator
DOFPDPNE_00393 1.8e-34 yabO J S4 domain protein
DOFPDPNE_00394 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DOFPDPNE_00395 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DOFPDPNE_00396 2.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DOFPDPNE_00397 7.6e-129 S (CBS) domain
DOFPDPNE_00398 1.3e-64 K transcriptional regulator
DOFPDPNE_00399 2.7e-18 K transcriptional regulator
DOFPDPNE_00400 2e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOFPDPNE_00401 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DOFPDPNE_00402 8.5e-255 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DOFPDPNE_00403 5.3e-264 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DOFPDPNE_00404 1.9e-39 rpmE2 J Ribosomal protein L31
DOFPDPNE_00405 9.1e-158 S Sucrose-6F-phosphate phosphohydrolase
DOFPDPNE_00406 2.1e-102 S LexA-binding, inner membrane-associated putative hydrolase
DOFPDPNE_00407 1e-21
DOFPDPNE_00408 2.3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DOFPDPNE_00410 1.1e-161 rssA S Phospholipase, patatin family
DOFPDPNE_00411 5e-17 S hydrolase
DOFPDPNE_00412 8.5e-39 S hydrolase
DOFPDPNE_00413 7.3e-130 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
DOFPDPNE_00414 8.2e-56 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
DOFPDPNE_00415 1.9e-119 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
DOFPDPNE_00416 1.5e-78 glvR K Helix-turn-helix domain, rpiR family
DOFPDPNE_00417 1.3e-23 glvR K Helix-turn-helix domain, rpiR family
DOFPDPNE_00419 3.1e-45
DOFPDPNE_00420 3.8e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DOFPDPNE_00421 6.7e-41
DOFPDPNE_00422 2.5e-18 C nitroreductase
DOFPDPNE_00423 6.6e-28 C nitroreductase
DOFPDPNE_00424 3.1e-240 yhdP S Transporter associated domain
DOFPDPNE_00425 1.5e-106 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DOFPDPNE_00426 1.9e-142 potE E amino acid
DOFPDPNE_00427 2.3e-130 M Glycosyl hydrolases family 25
DOFPDPNE_00428 3.7e-208 yfmL 3.6.4.13 L DEAD DEAH box helicase
DOFPDPNE_00429 1.1e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOFPDPNE_00431 2.7e-25
DOFPDPNE_00432 5.9e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DOFPDPNE_00433 5.3e-90 gtcA S Teichoic acid glycosylation protein
DOFPDPNE_00434 1.6e-79 fld C Flavodoxin
DOFPDPNE_00435 1.9e-163 map 3.4.11.18 E Methionine Aminopeptidase
DOFPDPNE_00436 2.5e-148 yihY S Belongs to the UPF0761 family
DOFPDPNE_00437 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DOFPDPNE_00438 0.0 2.7.7.73, 2.7.7.80 H ThiF family
DOFPDPNE_00439 1.2e-288 V ABC transporter transmembrane region
DOFPDPNE_00440 4e-15 L COG2826 Transposase and inactivated derivatives, IS30 family
DOFPDPNE_00441 1.2e-17
DOFPDPNE_00442 1.9e-16 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
DOFPDPNE_00443 6.6e-63 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
DOFPDPNE_00444 4.6e-36 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
DOFPDPNE_00445 1.6e-38 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
DOFPDPNE_00446 5.9e-70 S Iron-sulphur cluster biosynthesis
DOFPDPNE_00447 4.3e-195 ybiR P Citrate transporter
DOFPDPNE_00448 2.3e-96 lemA S LemA family
DOFPDPNE_00449 1e-162 htpX O Belongs to the peptidase M48B family
DOFPDPNE_00450 6.1e-66 L Helix-turn-helix domain
DOFPDPNE_00451 1.2e-18 L hmm pf00665
DOFPDPNE_00452 5.6e-08 L hmm pf00665
DOFPDPNE_00453 2.9e-60 L hmm pf00665
DOFPDPNE_00454 8.7e-173 K helix_turn_helix, arabinose operon control protein
DOFPDPNE_00455 2.3e-251 cbiO1 S ABC transporter, ATP-binding protein
DOFPDPNE_00456 1.4e-92 P Cobalt transport protein
DOFPDPNE_00457 3e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
DOFPDPNE_00458 2.1e-90 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DOFPDPNE_00459 6.9e-218 htrA 3.4.21.107 O serine protease
DOFPDPNE_00460 3.3e-149 vicX 3.1.26.11 S domain protein
DOFPDPNE_00461 6.9e-150 yycI S YycH protein
DOFPDPNE_00462 1.3e-243 yycH S YycH protein
DOFPDPNE_00463 2.8e-308 vicK 2.7.13.3 T Histidine kinase
DOFPDPNE_00464 9.7e-132 K response regulator
DOFPDPNE_00466 9.9e-29
DOFPDPNE_00467 0.0 cadA P P-type ATPase
DOFPDPNE_00468 2.8e-205 napA P Sodium/hydrogen exchanger family
DOFPDPNE_00469 1.5e-49 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
DOFPDPNE_00470 3e-30 S YoeB-like toxin of bacterial type II toxin-antitoxin system
DOFPDPNE_00471 9.1e-284 V ABC transporter transmembrane region
DOFPDPNE_00472 4e-81 S Putative adhesin
DOFPDPNE_00473 5.9e-160 mutR K Helix-turn-helix XRE-family like proteins
DOFPDPNE_00474 2.4e-46
DOFPDPNE_00475 4.6e-120 S CAAX protease self-immunity
DOFPDPNE_00476 1.3e-196 S DUF218 domain
DOFPDPNE_00477 1.2e-12 macB_3 V ABC transporter, ATP-binding protein
DOFPDPNE_00478 3.3e-181 macB_3 V ABC transporter, ATP-binding protein
DOFPDPNE_00479 8.9e-199 macB_3 V ABC transporter, ATP-binding protein
DOFPDPNE_00480 4.7e-95 S ECF transporter, substrate-specific component
DOFPDPNE_00481 3.4e-160 yeaE S Aldo/keto reductase family
DOFPDPNE_00482 1.4e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DOFPDPNE_00483 1.6e-66 ybbH_2 K rpiR family
DOFPDPNE_00485 5.5e-118 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
DOFPDPNE_00486 2.4e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
DOFPDPNE_00487 1.2e-146 cof S haloacid dehalogenase-like hydrolase
DOFPDPNE_00488 3.3e-231 pbuG S permease
DOFPDPNE_00489 2.2e-174 S cog cog1373
DOFPDPNE_00490 8.5e-87 uspA T universal stress protein
DOFPDPNE_00491 4.5e-153 phnD P Phosphonate ABC transporter
DOFPDPNE_00492 5.2e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DOFPDPNE_00493 6.5e-129 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
DOFPDPNE_00494 1.2e-149 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
DOFPDPNE_00495 2e-108 tag 3.2.2.20 L glycosylase
DOFPDPNE_00496 8.7e-84
DOFPDPNE_00497 3.4e-274 S Calcineurin-like phosphoesterase
DOFPDPNE_00498 0.0 asnB 6.3.5.4 E Asparagine synthase
DOFPDPNE_00499 2.8e-254 yxbA 6.3.1.12 S ATP-grasp enzyme
DOFPDPNE_00502 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
DOFPDPNE_00503 4.3e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DOFPDPNE_00504 4.1e-101 S Iron-sulfur cluster assembly protein
DOFPDPNE_00505 6.1e-232 XK27_04775 S PAS domain
DOFPDPNE_00506 7.9e-227 yttB EGP Major facilitator Superfamily
DOFPDPNE_00507 0.0 pepO 3.4.24.71 O Peptidase family M13
DOFPDPNE_00508 0.0 kup P Transport of potassium into the cell
DOFPDPNE_00509 1.5e-74
DOFPDPNE_00511 7.1e-30
DOFPDPNE_00512 1.4e-16 S Protein of unknown function (DUF2922)
DOFPDPNE_00513 2.4e-160 S SLAP domain
DOFPDPNE_00515 1.1e-49 K DNA-templated transcription, initiation
DOFPDPNE_00516 1.7e-63
DOFPDPNE_00517 4.4e-225 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DOFPDPNE_00518 1.3e-209 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
DOFPDPNE_00519 0.0 yjbQ P TrkA C-terminal domain protein
DOFPDPNE_00520 1.4e-133 gepA K Protein of unknown function (DUF4065)
DOFPDPNE_00521 7.5e-180 S Oxidoreductase family, NAD-binding Rossmann fold
DOFPDPNE_00522 1.2e-120
DOFPDPNE_00523 3.9e-81
DOFPDPNE_00524 1.8e-20
DOFPDPNE_00525 2.2e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOFPDPNE_00526 3e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DOFPDPNE_00527 5.3e-101 G Aldose 1-epimerase
DOFPDPNE_00528 7.8e-205 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DOFPDPNE_00529 7.3e-112 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DOFPDPNE_00530 0.0 XK27_08315 M Sulfatase
DOFPDPNE_00531 2.2e-265 S Fibronectin type III domain
DOFPDPNE_00532 1.3e-243 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DOFPDPNE_00533 1.2e-53
DOFPDPNE_00535 1.6e-257 pepC 3.4.22.40 E aminopeptidase
DOFPDPNE_00536 7.8e-120 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
DOFPDPNE_00537 3.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DOFPDPNE_00538 1.8e-256 pepC 3.4.22.40 E aminopeptidase
DOFPDPNE_00539 5.8e-58 hsp O Belongs to the small heat shock protein (HSP20) family
DOFPDPNE_00540 4.7e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DOFPDPNE_00541 4.9e-114
DOFPDPNE_00543 5.3e-115 E Belongs to the SOS response-associated peptidase family
DOFPDPNE_00544 2.8e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOFPDPNE_00545 1.5e-91 comEB 3.5.4.12 F MafB19-like deaminase
DOFPDPNE_00546 4.6e-109 S TPM domain
DOFPDPNE_00547 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
DOFPDPNE_00548 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOFPDPNE_00549 4.6e-148 tatD L hydrolase, TatD family
DOFPDPNE_00550 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DOFPDPNE_00551 1.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DOFPDPNE_00552 1e-38 veg S Biofilm formation stimulator VEG
DOFPDPNE_00553 5.3e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
DOFPDPNE_00554 4.2e-208 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DOFPDPNE_00555 7.7e-106 S SLAP domain
DOFPDPNE_00556 4.4e-131
DOFPDPNE_00557 8e-215 S SLAP domain
DOFPDPNE_00558 4.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOFPDPNE_00559 1.1e-55 2.7.1.2 GK ROK family
DOFPDPNE_00560 9.5e-69 GK ROK family
DOFPDPNE_00561 5.5e-43
DOFPDPNE_00562 1.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
DOFPDPNE_00563 5.5e-68 S Domain of unknown function (DUF1934)
DOFPDPNE_00564 9.7e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DOFPDPNE_00565 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DOFPDPNE_00566 5.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOFPDPNE_00567 1.4e-29 S Haloacid dehalogenase-like hydrolase
DOFPDPNE_00568 3.5e-42 S Haloacid dehalogenase-like hydrolase
DOFPDPNE_00569 5.7e-285 pipD E Dipeptidase
DOFPDPNE_00570 3.7e-159 msmR K AraC-like ligand binding domain
DOFPDPNE_00571 6.6e-224 pbuX F xanthine permease
DOFPDPNE_00572 9.6e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DOFPDPNE_00573 2.4e-83 S COG NOG38524 non supervised orthologous group
DOFPDPNE_00574 7.3e-194 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOFPDPNE_00575 1.2e-73 nrdI F Probably involved in ribonucleotide reductase function
DOFPDPNE_00576 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOFPDPNE_00577 4.8e-31 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
DOFPDPNE_00578 1.2e-154 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
DOFPDPNE_00579 7.5e-108 pncA Q Isochorismatase family
DOFPDPNE_00580 1.8e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DOFPDPNE_00581 9.7e-41 L transposase, IS605 OrfB family
DOFPDPNE_00582 3e-90 S VanZ like family
DOFPDPNE_00583 8.9e-133 yebC K Transcriptional regulatory protein
DOFPDPNE_00584 6e-177 comGA NU Type II IV secretion system protein
DOFPDPNE_00585 6.4e-174 comGB NU type II secretion system
DOFPDPNE_00586 1.1e-43 comGC U competence protein ComGC
DOFPDPNE_00587 2.1e-73
DOFPDPNE_00588 2.3e-41
DOFPDPNE_00589 4.2e-81 comGF U Putative Competence protein ComGF
DOFPDPNE_00590 7.8e-188 ytxK 2.1.1.72 L N-6 DNA Methylase
DOFPDPNE_00591 5.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOFPDPNE_00593 7.8e-33 M Protein of unknown function (DUF3737)
DOFPDPNE_00594 6.2e-32 M Protein of unknown function (DUF3737)
DOFPDPNE_00595 6.8e-228 patB 4.4.1.8 E Aminotransferase, class I
DOFPDPNE_00596 1.9e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
DOFPDPNE_00597 2.4e-60 S SdpI/YhfL protein family
DOFPDPNE_00598 8.3e-131 K Transcriptional regulatory protein, C terminal
DOFPDPNE_00599 2e-272 yclK 2.7.13.3 T Histidine kinase
DOFPDPNE_00600 4.3e-158 pstS P Phosphate
DOFPDPNE_00601 3.7e-174 pstC P probably responsible for the translocation of the substrate across the membrane
DOFPDPNE_00602 7e-156 pstA P Phosphate transport system permease protein PstA
DOFPDPNE_00603 1.1e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DOFPDPNE_00604 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DOFPDPNE_00605 7.5e-118 phoU P Plays a role in the regulation of phosphate uptake
DOFPDPNE_00606 4.3e-27 yfdV S Membrane transport protein
DOFPDPNE_00607 5.5e-159 yfdV S Membrane transport protein
DOFPDPNE_00608 5.4e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DOFPDPNE_00609 2.4e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DOFPDPNE_00610 7.1e-80 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
DOFPDPNE_00611 1.6e-117 rsmC 2.1.1.172 J Methyltransferase
DOFPDPNE_00612 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DOFPDPNE_00613 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOFPDPNE_00614 5e-38 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DOFPDPNE_00615 2.1e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DOFPDPNE_00616 4.9e-35 S Protein of unknown function (DUF2508)
DOFPDPNE_00617 8.7e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DOFPDPNE_00618 2.2e-51 yaaQ S Cyclic-di-AMP receptor
DOFPDPNE_00619 1.5e-155 holB 2.7.7.7 L DNA polymerase III
DOFPDPNE_00620 2.4e-59 yabA L Involved in initiation control of chromosome replication
DOFPDPNE_00621 7.9e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DOFPDPNE_00622 2.8e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
DOFPDPNE_00623 7.6e-86 S ECF transporter, substrate-specific component
DOFPDPNE_00624 6.2e-134 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
DOFPDPNE_00625 1.6e-105 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
DOFPDPNE_00626 3.1e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DOFPDPNE_00627 7.3e-189 cggR K Putative sugar-binding domain
DOFPDPNE_00628 1.3e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DOFPDPNE_00629 1.3e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DOFPDPNE_00630 2e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DOFPDPNE_00631 1.8e-95
DOFPDPNE_00632 7.4e-158 ycsE S Sucrose-6F-phosphate phosphohydrolase
DOFPDPNE_00633 3.3e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DOFPDPNE_00634 1.6e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DOFPDPNE_00635 6.4e-90 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
DOFPDPNE_00636 3.1e-98 dnaQ 2.7.7.7 L DNA polymerase III
DOFPDPNE_00637 1.1e-164 murB 1.3.1.98 M Cell wall formation
DOFPDPNE_00638 3.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DOFPDPNE_00639 1.3e-129 potB P ABC transporter permease
DOFPDPNE_00640 1.7e-132 potC P ABC transporter permease
DOFPDPNE_00641 1.6e-207 potD P ABC transporter
DOFPDPNE_00642 4.2e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DOFPDPNE_00643 1.2e-172 ybbR S YbbR-like protein
DOFPDPNE_00644 5.7e-258 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOFPDPNE_00645 2.1e-151 S hydrolase
DOFPDPNE_00646 9.9e-149 S Sucrose-6F-phosphate phosphohydrolase
DOFPDPNE_00647 1e-117
DOFPDPNE_00648 5.8e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOFPDPNE_00649 7.8e-216 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DOFPDPNE_00650 1.5e-63 licT K CAT RNA binding domain
DOFPDPNE_00651 3e-63 licT K CAT RNA binding domain
DOFPDPNE_00652 0.0 bglP G phosphotransferase system
DOFPDPNE_00653 1.3e-151 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFPDPNE_00654 6.1e-122 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFPDPNE_00655 2.6e-185 D Alpha beta
DOFPDPNE_00656 2.3e-54 E Amino acid permease
DOFPDPNE_00657 8.7e-151 E Amino acid permease
DOFPDPNE_00658 4e-33 E Amino acid permease
DOFPDPNE_00659 9.9e-112 ybbL S ABC transporter, ATP-binding protein
DOFPDPNE_00660 4.3e-130 ybbM S Uncharacterised protein family (UPF0014)
DOFPDPNE_00661 2.9e-138 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DOFPDPNE_00662 8e-24 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DOFPDPNE_00663 2.8e-105 K Bacterial regulatory proteins, tetR family
DOFPDPNE_00664 1.3e-254 V Restriction endonuclease
DOFPDPNE_00665 3.5e-39 pipD E Dipeptidase
DOFPDPNE_00666 7.9e-155 pipD E Dipeptidase
DOFPDPNE_00667 3.8e-233 S LPXTG cell wall anchor motif
DOFPDPNE_00668 1.6e-148 S Putative ABC-transporter type IV
DOFPDPNE_00669 1.3e-99 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
DOFPDPNE_00670 2.4e-87 S ECF transporter, substrate-specific component
DOFPDPNE_00671 2.1e-67 S Domain of unknown function (DUF4430)
DOFPDPNE_00672 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
DOFPDPNE_00673 2.9e-177 K AI-2E family transporter
DOFPDPNE_00674 1.4e-104 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
DOFPDPNE_00675 1.5e-142 K Helix-turn-helix XRE-family like proteins
DOFPDPNE_00676 8.9e-150 K Helix-turn-helix XRE-family like proteins
DOFPDPNE_00677 7.3e-92 S Protein of unknown function (DUF3232)
DOFPDPNE_00678 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOFPDPNE_00679 4.2e-217 iscS2 2.8.1.7 E Aminotransferase class V
DOFPDPNE_00680 3.2e-282 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DOFPDPNE_00681 4.7e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DOFPDPNE_00682 1e-81 yueI S Protein of unknown function (DUF1694)
DOFPDPNE_00683 5.5e-242 rarA L recombination factor protein RarA
DOFPDPNE_00684 2.5e-35
DOFPDPNE_00685 3.1e-78 usp6 T universal stress protein
DOFPDPNE_00686 1.9e-217 rodA D Belongs to the SEDS family
DOFPDPNE_00687 8.6e-34 S Protein of unknown function (DUF2969)
DOFPDPNE_00688 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
DOFPDPNE_00689 5e-179 mbl D Cell shape determining protein MreB Mrl
DOFPDPNE_00690 9e-31 ywzB S Protein of unknown function (DUF1146)
DOFPDPNE_00691 7.7e-55 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DOFPDPNE_00692 6.3e-239 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DOFPDPNE_00693 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DOFPDPNE_00694 2.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DOFPDPNE_00695 4.7e-94 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOFPDPNE_00696 5e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DOFPDPNE_00697 1.2e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOFPDPNE_00698 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
DOFPDPNE_00699 2.6e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DOFPDPNE_00700 2.9e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DOFPDPNE_00701 3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DOFPDPNE_00702 5.3e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DOFPDPNE_00703 7.6e-114 tdk 2.7.1.21 F thymidine kinase
DOFPDPNE_00704 2.2e-249 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
DOFPDPNE_00707 1.2e-196 ampC V Beta-lactamase
DOFPDPNE_00708 9.1e-42 IQ reductase
DOFPDPNE_00709 3.3e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
DOFPDPNE_00710 7e-220 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DOFPDPNE_00711 3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DOFPDPNE_00712 5.5e-114 S Protein of unknown function (DUF1211)
DOFPDPNE_00713 3.8e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOFPDPNE_00714 2.8e-148 L restriction endonuclease
DOFPDPNE_00715 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
DOFPDPNE_00716 1.9e-169 L COG2826 Transposase and inactivated derivatives, IS30 family
DOFPDPNE_00717 0.0 S SH3-like domain
DOFPDPNE_00718 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DOFPDPNE_00719 1.1e-12 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DOFPDPNE_00720 6.1e-143 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DOFPDPNE_00721 4.8e-70 arcC 2.7.2.2 E Belongs to the carbamate kinase family
DOFPDPNE_00722 2.8e-52 arcC 2.7.2.2 E Belongs to the carbamate kinase family
DOFPDPNE_00723 3.4e-97 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
DOFPDPNE_00724 7.4e-214 S Sterol carrier protein domain
DOFPDPNE_00725 1.1e-19
DOFPDPNE_00726 3.5e-106 K LysR substrate binding domain
DOFPDPNE_00727 9e-251 yifK E Amino acid permease
DOFPDPNE_00728 6.7e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DOFPDPNE_00729 6.2e-96 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DOFPDPNE_00730 2.8e-15 ps301 K sequence-specific DNA binding
DOFPDPNE_00731 0.0 aha1 P E1-E2 ATPase
DOFPDPNE_00732 5.7e-163 metQ1 P Belongs to the nlpA lipoprotein family
DOFPDPNE_00733 2.1e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOFPDPNE_00734 2.9e-88 metI P ABC transporter permease
DOFPDPNE_00736 4.5e-54
DOFPDPNE_00737 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
DOFPDPNE_00738 5.4e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DOFPDPNE_00739 1.1e-291 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOFPDPNE_00740 6.5e-64
DOFPDPNE_00741 0.0 FbpA K Fibronectin-binding protein
DOFPDPNE_00742 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
DOFPDPNE_00743 2.1e-199 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DOFPDPNE_00744 1.5e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOFPDPNE_00745 9.5e-80 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DOFPDPNE_00746 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DOFPDPNE_00747 1.6e-14 cpdA S Calcineurin-like phosphoesterase
DOFPDPNE_00748 1.9e-47 cpdA S Calcineurin-like phosphoesterase
DOFPDPNE_00749 2.6e-87 cpdA S Calcineurin-like phosphoesterase
DOFPDPNE_00750 3.2e-10 cpdA S Calcineurin-like phosphoesterase
DOFPDPNE_00751 1.5e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DOFPDPNE_00752 6.1e-70 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DOFPDPNE_00753 7.7e-108 ypsA S Belongs to the UPF0398 family
DOFPDPNE_00754 7e-118 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DOFPDPNE_00755 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
DOFPDPNE_00756 3.9e-113 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DOFPDPNE_00757 7.4e-115 dnaD L DnaD domain protein
DOFPDPNE_00758 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
DOFPDPNE_00759 2.9e-90 ypmB S Protein conserved in bacteria
DOFPDPNE_00760 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DOFPDPNE_00761 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DOFPDPNE_00762 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DOFPDPNE_00763 6.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
DOFPDPNE_00764 3.4e-180 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
DOFPDPNE_00765 1.9e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
DOFPDPNE_00766 5.7e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DOFPDPNE_00767 3e-262 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
DOFPDPNE_00768 9.1e-181
DOFPDPNE_00769 4.4e-143
DOFPDPNE_00770 7.2e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DOFPDPNE_00771 7.8e-28
DOFPDPNE_00772 1.8e-253 rarA L recombination factor protein RarA
DOFPDPNE_00773 9.9e-127
DOFPDPNE_00774 1e-148
DOFPDPNE_00775 1.3e-148
DOFPDPNE_00776 2.8e-123 skfE V ATPases associated with a variety of cellular activities
DOFPDPNE_00777 5e-60 yvoA_1 K Transcriptional regulator, GntR family
DOFPDPNE_00778 1.4e-242 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DOFPDPNE_00779 1.5e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DOFPDPNE_00780 7.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
DOFPDPNE_00781 6e-31 mutT 3.6.1.55 F NUDIX domain
DOFPDPNE_00782 1.6e-125 S Peptidase family M23
DOFPDPNE_00783 6.4e-199 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DOFPDPNE_00784 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DOFPDPNE_00785 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DOFPDPNE_00786 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DOFPDPNE_00787 1e-136 recO L Involved in DNA repair and RecF pathway recombination
DOFPDPNE_00788 3.3e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DOFPDPNE_00789 1.7e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DOFPDPNE_00790 2.9e-176 phoH T phosphate starvation-inducible protein PhoH
DOFPDPNE_00791 1.5e-69 yqeY S YqeY-like protein
DOFPDPNE_00792 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DOFPDPNE_00793 2e-152 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DOFPDPNE_00794 2.9e-104 S Peptidase family M23
DOFPDPNE_00795 3.4e-163 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOFPDPNE_00796 6.5e-75 yvdE K helix_turn _helix lactose operon repressor
DOFPDPNE_00797 2.4e-37 yvdE K helix_turn _helix lactose operon repressor
DOFPDPNE_00798 3.4e-169 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
DOFPDPNE_00799 1.8e-254 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DOFPDPNE_00800 9.7e-69 rplI J Binds to the 23S rRNA
DOFPDPNE_00801 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DOFPDPNE_00804 3.6e-160 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DOFPDPNE_00805 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
DOFPDPNE_00806 7e-146 cycA E Amino acid permease
DOFPDPNE_00807 1.9e-245 yifK E Amino acid permease
DOFPDPNE_00808 5.2e-92 puuD S peptidase C26
DOFPDPNE_00809 1.8e-22 puuD S peptidase C26
DOFPDPNE_00810 3.5e-239 steT_1 E amino acid
DOFPDPNE_00811 2.7e-26
DOFPDPNE_00812 7.8e-121
DOFPDPNE_00813 1.2e-129 ecfA P ABC-type multidrug transport system ATPase component
DOFPDPNE_00815 1.1e-81 M NlpC/P60 family
DOFPDPNE_00816 1.9e-136 EG EamA-like transporter family
DOFPDPNE_00817 2.1e-109
DOFPDPNE_00818 3.9e-79
DOFPDPNE_00819 4.2e-16 XK27_05540 S DUF218 domain
DOFPDPNE_00820 1.7e-84
DOFPDPNE_00821 6.1e-58
DOFPDPNE_00822 3.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DOFPDPNE_00823 7.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DOFPDPNE_00824 4.7e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DOFPDPNE_00827 2.6e-202 4.2.1.126 S Bacterial protein of unknown function (DUF871)
DOFPDPNE_00828 3.9e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
DOFPDPNE_00829 3.5e-194 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
DOFPDPNE_00830 1.2e-185 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
DOFPDPNE_00831 3e-150 noxC 1.5.1.39 C Nitroreductase
DOFPDPNE_00832 3e-12
DOFPDPNE_00833 2.2e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOFPDPNE_00834 9.8e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOFPDPNE_00835 1.6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DOFPDPNE_00836 4.7e-151 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DOFPDPNE_00837 3.3e-308 recN L May be involved in recombinational repair of damaged DNA
DOFPDPNE_00838 2.4e-80 6.3.3.2 S ASCH
DOFPDPNE_00839 4e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DOFPDPNE_00840 6.5e-34 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DOFPDPNE_00841 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOFPDPNE_00842 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DOFPDPNE_00843 2e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DOFPDPNE_00844 9.2e-147 stp 3.1.3.16 T phosphatase
DOFPDPNE_00845 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
DOFPDPNE_00846 1.1e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DOFPDPNE_00847 5e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DOFPDPNE_00848 6.2e-128 thiN 2.7.6.2 H thiamine pyrophosphokinase
DOFPDPNE_00849 3.6e-51
DOFPDPNE_00850 1.1e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DOFPDPNE_00851 6.8e-57 asp S Asp23 family, cell envelope-related function
DOFPDPNE_00852 1.1e-306 yloV S DAK2 domain fusion protein YloV
DOFPDPNE_00853 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DOFPDPNE_00854 5.8e-183 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DOFPDPNE_00855 3.4e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOFPDPNE_00856 7.3e-197 oppD P Belongs to the ABC transporter superfamily
DOFPDPNE_00857 2.8e-182 oppF P Belongs to the ABC transporter superfamily
DOFPDPNE_00858 1.7e-176 oppB P ABC transporter permease
DOFPDPNE_00859 6.6e-149 oppC P Binding-protein-dependent transport system inner membrane component
DOFPDPNE_00860 0.0 oppA E ABC transporter substrate-binding protein
DOFPDPNE_00861 8.6e-43 L Transposase
DOFPDPNE_00862 1.3e-104 E GDSL-like Lipase/Acylhydrolase
DOFPDPNE_00863 1.3e-170 coaA 2.7.1.33 F Pantothenic acid kinase
DOFPDPNE_00864 2.2e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOFPDPNE_00865 1.3e-246 G Bacterial extracellular solute-binding protein
DOFPDPNE_00866 4e-66 S Peptidase propeptide and YPEB domain
DOFPDPNE_00868 1.3e-95 F Nucleoside 2-deoxyribosyltransferase
DOFPDPNE_00869 1.3e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DOFPDPNE_00870 1.2e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
DOFPDPNE_00871 8.4e-277 V ABC transporter transmembrane region
DOFPDPNE_00872 2.4e-11
DOFPDPNE_00873 2e-140 pnuC H nicotinamide mononucleotide transporter
DOFPDPNE_00874 9.6e-68 S Protein of unknown function (DUF3290)
DOFPDPNE_00875 2.8e-38
DOFPDPNE_00876 4.3e-277 pipD E Dipeptidase
DOFPDPNE_00877 8.8e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
DOFPDPNE_00878 1.5e-168 hrtB V ABC transporter permease
DOFPDPNE_00879 3.5e-94 ygfC K Bacterial regulatory proteins, tetR family
DOFPDPNE_00880 1.2e-111 G phosphoglycerate mutase
DOFPDPNE_00881 4.4e-143 aroD S Alpha/beta hydrolase family
DOFPDPNE_00882 2.6e-143 S Belongs to the UPF0246 family
DOFPDPNE_00883 3.1e-121
DOFPDPNE_00884 1.1e-07
DOFPDPNE_00885 1.2e-170 dtpT U amino acid peptide transporter
DOFPDPNE_00886 1e-34 dtpT U amino acid peptide transporter
DOFPDPNE_00887 0.0 pepN 3.4.11.2 E aminopeptidase
DOFPDPNE_00888 5e-60 lysM M LysM domain
DOFPDPNE_00889 1.1e-170
DOFPDPNE_00890 2.6e-212 mdtG EGP Major facilitator Superfamily
DOFPDPNE_00891 4.4e-213 lacZ 3.2.1.23 G -beta-galactosidase
DOFPDPNE_00892 0.0 lacS G Transporter
DOFPDPNE_00893 4e-57 lacS G Transporter
DOFPDPNE_00894 1.8e-71 lacS G Transporter
DOFPDPNE_00895 1.2e-47 lacS G Transporter
DOFPDPNE_00896 1.9e-24 lacS G Transporter
DOFPDPNE_00897 1.4e-189 lacR K Transcriptional regulator
DOFPDPNE_00898 2.2e-290 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
DOFPDPNE_00899 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
DOFPDPNE_00900 9.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
DOFPDPNE_00901 2.5e-197 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DOFPDPNE_00902 5.3e-155 ydjP I Alpha/beta hydrolase family
DOFPDPNE_00903 3.6e-274 P Sodium:sulfate symporter transmembrane region
DOFPDPNE_00904 1.1e-258 pepC 3.4.22.40 E Peptidase C1-like family
DOFPDPNE_00905 2.7e-54
DOFPDPNE_00906 4.9e-77 fhaB M Rib/alpha-like repeat
DOFPDPNE_00907 1.3e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DOFPDPNE_00909 3.3e-38 UW LPXTG-motif cell wall anchor domain protein
DOFPDPNE_00910 3.5e-09 UW LPXTG-motif cell wall anchor domain protein
DOFPDPNE_00911 1.5e-15 S YSIRK type signal peptide
DOFPDPNE_00912 1.3e-140 S YSIRK type signal peptide
DOFPDPNE_00913 6.2e-13 M domain protein
DOFPDPNE_00915 1.5e-57 M domain protein
DOFPDPNE_00916 3.2e-10 M domain protein
DOFPDPNE_00917 5.4e-264 frdC 1.3.5.4 C FAD binding domain
DOFPDPNE_00918 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DOFPDPNE_00919 1.7e-34
DOFPDPNE_00920 5.9e-60 S cog cog1373
DOFPDPNE_00921 1.8e-10 S cog cog1373
DOFPDPNE_00922 9.1e-48 S cog cog1373
DOFPDPNE_00924 4.8e-60 KLT Protein kinase domain
DOFPDPNE_00925 7.7e-280 KLT Protein kinase domain
DOFPDPNE_00926 1.9e-127 3.6.1.13, 3.6.1.55 F NUDIX domain
DOFPDPNE_00927 2e-32 L COG2963 Transposase and inactivated derivatives
DOFPDPNE_00928 1.3e-102 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFPDPNE_00929 5.8e-08 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFPDPNE_00930 7.2e-135 gmuR K UTRA
DOFPDPNE_00931 1.1e-61 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOFPDPNE_00932 6.9e-128
DOFPDPNE_00933 4.9e-119 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DOFPDPNE_00934 0.0 clpE O AAA domain (Cdc48 subfamily)
DOFPDPNE_00935 8.6e-173 S Alpha/beta hydrolase of unknown function (DUF915)
DOFPDPNE_00936 8.7e-213 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOFPDPNE_00937 9.7e-22 XK27_06785 V ABC transporter, ATP-binding protein
DOFPDPNE_00938 3.9e-63 XK27_06785 V ABC transporter, ATP-binding protein
DOFPDPNE_00939 2.1e-103 XK27_06780 V ABC transporter permease
DOFPDPNE_00940 2.3e-70 XK27_06780 V ABC transporter permease
DOFPDPNE_00941 1.3e-148 XK27_06780 V ABC transporter permease
DOFPDPNE_00942 3e-37
DOFPDPNE_00943 9.7e-289 ytgP S Polysaccharide biosynthesis protein
DOFPDPNE_00944 4e-145 lysA2 M Glycosyl hydrolases family 25
DOFPDPNE_00945 3.5e-94 S Protein of unknown function (DUF975)
DOFPDPNE_00946 2.6e-49
DOFPDPNE_00947 4.1e-28
DOFPDPNE_00948 8.7e-125 S CAAX protease self-immunity
DOFPDPNE_00949 3.4e-10
DOFPDPNE_00951 2.1e-174 pbpX2 V Beta-lactamase
DOFPDPNE_00952 3.5e-249 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DOFPDPNE_00953 5.7e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFPDPNE_00954 2.9e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
DOFPDPNE_00955 5.5e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOFPDPNE_00956 5.2e-19 S D-Ala-teichoic acid biosynthesis protein
DOFPDPNE_00957 2.2e-50
DOFPDPNE_00958 1e-215 ywhK S Membrane
DOFPDPNE_00959 5.6e-25 ykuL S IMP dehydrogenase activity
DOFPDPNE_00960 4.6e-216 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
DOFPDPNE_00961 7.9e-219 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
DOFPDPNE_00962 1e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
DOFPDPNE_00963 5.5e-46
DOFPDPNE_00964 3.8e-18 D Alpha beta
DOFPDPNE_00965 8.9e-209 glf 5.4.99.9 M UDP-galactopyranose mutase
DOFPDPNE_00966 1.6e-105 lgtD S glycosyl transferase family 2
DOFPDPNE_00967 2.9e-197
DOFPDPNE_00968 3e-150 M Domain of unknown function (DUF4422)
DOFPDPNE_00969 1.9e-33 GT4 M Glycosyl transferases group 1
DOFPDPNE_00970 3.7e-94 GT4 M Glycosyl transferases group 1
DOFPDPNE_00971 4.3e-18 GT4 M Glycosyl transferases group 1
DOFPDPNE_00972 8.1e-47 waaB GT4 M Glycosyl transferases group 1
DOFPDPNE_00973 9.5e-22 waaB GT4 M Glycosyl transferases group 1
DOFPDPNE_00974 4.4e-107 M Glycosyl transferases group 1
DOFPDPNE_00975 2.5e-150 M Glycosyl transferases group 1
DOFPDPNE_00976 7e-121 rfbP M Bacterial sugar transferase
DOFPDPNE_00977 1.8e-144 ywqE 3.1.3.48 GM PHP domain protein
DOFPDPNE_00978 2.5e-120 ywqD 2.7.10.1 D Capsular exopolysaccharide family
DOFPDPNE_00979 5.5e-145 epsB M biosynthesis protein
DOFPDPNE_00980 1.8e-179 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DOFPDPNE_00981 5e-200 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DOFPDPNE_00984 9.6e-140 M NlpC/P60 family
DOFPDPNE_00985 2.9e-46 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOFPDPNE_00986 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
DOFPDPNE_00987 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
DOFPDPNE_00988 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
DOFPDPNE_00989 9.7e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
DOFPDPNE_00990 1.4e-209 msmX P Belongs to the ABC transporter superfamily
DOFPDPNE_00991 7.3e-212 malE G Bacterial extracellular solute-binding protein
DOFPDPNE_00992 5.1e-251 malF P Binding-protein-dependent transport system inner membrane component
DOFPDPNE_00993 4.1e-153 malG P ABC transporter permease
DOFPDPNE_00994 1.3e-33 ymdB S Macro domain protein
DOFPDPNE_00995 4.5e-29 tnpR L Resolvase, N terminal domain
DOFPDPNE_00996 3.1e-29 L transposase, IS605 OrfB family
DOFPDPNE_00997 6.5e-54 arcA 3.5.3.6 E Arginine
DOFPDPNE_00998 3.2e-26 arcA 3.5.3.6 E Arginine
DOFPDPNE_00999 2.1e-157 lysR5 K LysR substrate binding domain
DOFPDPNE_01000 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
DOFPDPNE_01001 7.3e-86 3.4.21.96 S SLAP domain
DOFPDPNE_01002 2.3e-268 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOFPDPNE_01003 4.2e-152 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
DOFPDPNE_01004 9.5e-172 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DOFPDPNE_01005 3.7e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DOFPDPNE_01006 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
DOFPDPNE_01007 2.1e-120 srtA 3.4.22.70 M sortase family
DOFPDPNE_01008 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DOFPDPNE_01009 3.7e-82 S Aminoacyl-tRNA editing domain
DOFPDPNE_01010 6.7e-152 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOFPDPNE_01011 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DOFPDPNE_01012 5.1e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOFPDPNE_01013 3.6e-63 yodB K Transcriptional regulator, HxlR family
DOFPDPNE_01014 1.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DOFPDPNE_01015 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOFPDPNE_01016 8.3e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DOFPDPNE_01017 8.7e-170 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
DOFPDPNE_01018 1.3e-56 S Phage derived protein Gp49-like (DUF891)
DOFPDPNE_01019 2.4e-38 K Helix-turn-helix domain
DOFPDPNE_01020 5.7e-112 K WHG domain
DOFPDPNE_01021 9.9e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
DOFPDPNE_01022 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
DOFPDPNE_01023 5.1e-150 3.1.3.48 T Tyrosine phosphatase family
DOFPDPNE_01024 1.7e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DOFPDPNE_01025 1.9e-84 cvpA S Colicin V production protein
DOFPDPNE_01026 2.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DOFPDPNE_01027 4.6e-149 noc K Belongs to the ParB family
DOFPDPNE_01028 1.7e-137 soj D Sporulation initiation inhibitor
DOFPDPNE_01029 4.5e-155 spo0J K Belongs to the ParB family
DOFPDPNE_01030 2.1e-44 yyzM S Bacterial protein of unknown function (DUF951)
DOFPDPNE_01031 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DOFPDPNE_01032 6.8e-139 XK27_01040 S Protein of unknown function (DUF1129)
DOFPDPNE_01033 4.6e-297 V ABC transporter, ATP-binding protein
DOFPDPNE_01034 0.0 V ABC transporter
DOFPDPNE_01035 5.1e-122 K response regulator
DOFPDPNE_01036 1.4e-209 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
DOFPDPNE_01037 3.2e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DOFPDPNE_01038 7.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
DOFPDPNE_01039 2.4e-74 S Archaea bacterial proteins of unknown function
DOFPDPNE_01040 2.3e-127 S Archaea bacterial proteins of unknown function
DOFPDPNE_01041 8.8e-15 S Enterocin A Immunity
DOFPDPNE_01042 1.8e-44 S Enterocin A Immunity
DOFPDPNE_01043 6.6e-34 yozG K Transcriptional regulator
DOFPDPNE_01044 7.1e-33
DOFPDPNE_01045 8.7e-27
DOFPDPNE_01048 1.4e-139 fruR K DeoR C terminal sensor domain
DOFPDPNE_01049 4.8e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DOFPDPNE_01050 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
DOFPDPNE_01051 1e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
DOFPDPNE_01052 2.7e-169 psaA P Belongs to the bacterial solute-binding protein 9 family
DOFPDPNE_01053 5.5e-118 fhuC P ABC transporter
DOFPDPNE_01054 1.1e-131 znuB U ABC 3 transport family
DOFPDPNE_01055 6e-239 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DOFPDPNE_01056 4.9e-184 S AAA domain
DOFPDPNE_01057 2e-79 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOFPDPNE_01058 5.5e-23
DOFPDPNE_01059 4.6e-163 czcD P cation diffusion facilitator family transporter
DOFPDPNE_01060 1.2e-126 pgm3 G Belongs to the phosphoglycerate mutase family
DOFPDPNE_01061 2.2e-134 S membrane transporter protein
DOFPDPNE_01062 2.4e-66 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DOFPDPNE_01063 2.5e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
DOFPDPNE_01064 1.1e-71 S Protein of unknown function (DUF805)
DOFPDPNE_01065 3e-46
DOFPDPNE_01066 1.6e-67
DOFPDPNE_01067 1.3e-81 C Flavodoxin
DOFPDPNE_01068 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DOFPDPNE_01069 4e-78 ktrB P Potassium uptake protein
DOFPDPNE_01070 2.5e-247 ynbB 4.4.1.1 P aluminum resistance
DOFPDPNE_01071 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
DOFPDPNE_01072 2e-94 L An automated process has identified a potential problem with this gene model
DOFPDPNE_01073 1.5e-72 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
DOFPDPNE_01074 4.8e-38
DOFPDPNE_01075 6.5e-276 E Amino acid permease
DOFPDPNE_01076 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
DOFPDPNE_01077 4e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DOFPDPNE_01078 3.3e-97
DOFPDPNE_01079 1.4e-30 L COG2963 Transposase and inactivated derivatives
DOFPDPNE_01080 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
DOFPDPNE_01081 1.6e-60 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
DOFPDPNE_01084 3.1e-35 mta K helix_turn_helix, mercury resistance
DOFPDPNE_01085 6.6e-38 mta K helix_turn_helix, mercury resistance
DOFPDPNE_01086 7.5e-94 yyaR K Acetyltransferase (GNAT) domain
DOFPDPNE_01087 0.0 uvrA3 L excinuclease ABC, A subunit
DOFPDPNE_01090 1.7e-105 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
DOFPDPNE_01091 6.6e-75 K LytTr DNA-binding domain
DOFPDPNE_01092 2.7e-73 S Protein of unknown function (DUF3021)
DOFPDPNE_01093 1.7e-19 I alpha/beta hydrolase fold
DOFPDPNE_01094 7.6e-130 yibF S overlaps another CDS with the same product name
DOFPDPNE_01095 1.7e-202 yibE S overlaps another CDS with the same product name
DOFPDPNE_01096 1.5e-95
DOFPDPNE_01097 4.7e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DOFPDPNE_01098 2.2e-232 S Cysteine-rich secretory protein family
DOFPDPNE_01099 8.1e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOFPDPNE_01100 1.7e-263 glnPH2 P ABC transporter permease
DOFPDPNE_01101 7.4e-105
DOFPDPNE_01102 6.4e-125 luxT K Bacterial regulatory proteins, tetR family
DOFPDPNE_01103 1.3e-182 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOFPDPNE_01104 9.5e-66
DOFPDPNE_01105 1e-116 GM NmrA-like family
DOFPDPNE_01106 2.5e-126 S Alpha/beta hydrolase family
DOFPDPNE_01107 4.7e-159 epsV 2.7.8.12 S glycosyl transferase family 2
DOFPDPNE_01108 8.8e-141 ypuA S Protein of unknown function (DUF1002)
DOFPDPNE_01109 5.6e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOFPDPNE_01110 1e-178 S Alpha/beta hydrolase of unknown function (DUF915)
DOFPDPNE_01111 3.1e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOFPDPNE_01112 3.5e-85
DOFPDPNE_01113 1.7e-133 cobB K SIR2 family
DOFPDPNE_01114 3.7e-93 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
DOFPDPNE_01115 3.8e-121 terC P Integral membrane protein TerC family
DOFPDPNE_01116 8.2e-63 yeaO S Protein of unknown function, DUF488
DOFPDPNE_01117 2.5e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
DOFPDPNE_01118 4.6e-291 glnP P ABC transporter permease
DOFPDPNE_01119 3.3e-138 glnQ E ABC transporter, ATP-binding protein
DOFPDPNE_01120 2.4e-161 L HNH nucleases
DOFPDPNE_01121 1.7e-122 yfbR S HD containing hydrolase-like enzyme
DOFPDPNE_01123 8.6e-19 S Peptidase propeptide and YPEB domain
DOFPDPNE_01124 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
DOFPDPNE_01125 7.9e-55
DOFPDPNE_01126 1.1e-145 glcU U sugar transport
DOFPDPNE_01127 6e-268 pepC 3.4.22.40 E Peptidase C1-like family
DOFPDPNE_01128 1e-133 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DOFPDPNE_01129 9e-231 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
DOFPDPNE_01130 4.9e-110 G Phosphoglycerate mutase family
DOFPDPNE_01131 1.1e-195 D nuclear chromosome segregation
DOFPDPNE_01132 9.5e-76 M LysM domain protein
DOFPDPNE_01133 5.6e-13
DOFPDPNE_01134 7.1e-25 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
DOFPDPNE_01135 1.5e-95 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
DOFPDPNE_01136 2.1e-67
DOFPDPNE_01137 7.1e-32
DOFPDPNE_01138 4.1e-71 S Iron-sulphur cluster biosynthesis
DOFPDPNE_01139 2.8e-238 G Bacterial extracellular solute-binding protein
DOFPDPNE_01140 1.3e-246 XK27_08635 S UPF0210 protein
DOFPDPNE_01141 2.3e-41 gcvR T Belongs to the UPF0237 family
DOFPDPNE_01142 1.5e-205
DOFPDPNE_01143 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DOFPDPNE_01144 1.7e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DOFPDPNE_01145 1.4e-127 S Haloacid dehalogenase-like hydrolase
DOFPDPNE_01146 2.1e-114 radC L DNA repair protein
DOFPDPNE_01147 6.4e-174 mreB D cell shape determining protein MreB
DOFPDPNE_01148 1e-148 mreC M Involved in formation and maintenance of cell shape
DOFPDPNE_01149 1.1e-95 mreD
DOFPDPNE_01150 6.5e-13 S Protein of unknown function (DUF4044)
DOFPDPNE_01151 2.2e-54 S Protein of unknown function (DUF3397)
DOFPDPNE_01152 1.8e-77 mraZ K Belongs to the MraZ family
DOFPDPNE_01153 2e-183 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DOFPDPNE_01154 1.4e-54 ftsL D Cell division protein FtsL
DOFPDPNE_01155 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
DOFPDPNE_01156 1.3e-34 ftsI 3.4.16.4 M Penicillin-binding Protein
DOFPDPNE_01157 7.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOFPDPNE_01158 6.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DOFPDPNE_01159 8e-210 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DOFPDPNE_01160 2.9e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DOFPDPNE_01161 1.3e-233 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DOFPDPNE_01162 4.7e-209 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DOFPDPNE_01163 1.3e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DOFPDPNE_01164 9e-47 yggT S YGGT family
DOFPDPNE_01165 9.7e-149 ylmH S S4 domain protein
DOFPDPNE_01166 9.8e-101 gpsB D DivIVA domain protein
DOFPDPNE_01167 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DOFPDPNE_01168 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
DOFPDPNE_01169 3.4e-103 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
DOFPDPNE_01170 1.9e-39
DOFPDPNE_01171 2.9e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DOFPDPNE_01172 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
DOFPDPNE_01173 1.4e-56 XK27_04120 S Putative amino acid metabolism
DOFPDPNE_01174 2.7e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DOFPDPNE_01175 7.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DOFPDPNE_01176 2e-104 S Repeat protein
DOFPDPNE_01177 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DOFPDPNE_01178 3.8e-105 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
DOFPDPNE_01179 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOFPDPNE_01180 4.2e-33 ykzG S Belongs to the UPF0356 family
DOFPDPNE_01181 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DOFPDPNE_01182 0.0 typA T GTP-binding protein TypA
DOFPDPNE_01183 4.7e-208 ftsW D Belongs to the SEDS family
DOFPDPNE_01184 1.1e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
DOFPDPNE_01185 2.2e-96 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
DOFPDPNE_01186 2.7e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DOFPDPNE_01187 6.4e-193 ylbL T Belongs to the peptidase S16 family
DOFPDPNE_01188 2.5e-84 comEA L Competence protein ComEA
DOFPDPNE_01189 0.0 comEC S Competence protein ComEC
DOFPDPNE_01190 4.8e-174 holA 2.7.7.7 L DNA polymerase III delta subunit
DOFPDPNE_01191 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
DOFPDPNE_01192 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DOFPDPNE_01193 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOFPDPNE_01194 1.3e-151
DOFPDPNE_01195 3.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DOFPDPNE_01196 3.3e-205 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DOFPDPNE_01197 5.7e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DOFPDPNE_01198 1.3e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
DOFPDPNE_01199 3.4e-146 sufC O FeS assembly ATPase SufC
DOFPDPNE_01200 2.3e-229 sufD O FeS assembly protein SufD
DOFPDPNE_01201 1.5e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DOFPDPNE_01202 3.8e-81 nifU C SUF system FeS assembly protein, NifU family
DOFPDPNE_01203 1.4e-272 sufB O assembly protein SufB
DOFPDPNE_01204 2.5e-55 yitW S Iron-sulfur cluster assembly protein
DOFPDPNE_01205 2.9e-63 S Enterocin A Immunity
DOFPDPNE_01206 3.8e-134 glcR K DeoR C terminal sensor domain
DOFPDPNE_01207 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
DOFPDPNE_01208 6e-20 ynbB 4.4.1.1 P aluminum resistance
DOFPDPNE_01209 5e-62 ynbB 4.4.1.1 P aluminum resistance
DOFPDPNE_01210 1.4e-264 glnA 6.3.1.2 E glutamine synthetase
DOFPDPNE_01211 1.9e-109
DOFPDPNE_01212 2.9e-165
DOFPDPNE_01213 2e-151
DOFPDPNE_01214 4.4e-149 hsdS2 2.1.1.72 L N-6 DNA Methylase
DOFPDPNE_01215 0.0 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
DOFPDPNE_01216 5.4e-286 hsdM 2.1.1.72 V type I restriction-modification system
DOFPDPNE_01217 2.6e-147 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
DOFPDPNE_01218 7.1e-34
DOFPDPNE_01221 5.4e-19 K Transcriptional regulator, TetR family
DOFPDPNE_01225 2.9e-10
DOFPDPNE_01227 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOFPDPNE_01228 5.3e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DOFPDPNE_01229 1.5e-106 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DOFPDPNE_01230 4.1e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DOFPDPNE_01231 1.2e-247 dnaB L Replication initiation and membrane attachment
DOFPDPNE_01232 2.6e-166 dnaI L Primosomal protein DnaI
DOFPDPNE_01233 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DOFPDPNE_01234 2.9e-13
DOFPDPNE_01235 1.8e-50
DOFPDPNE_01236 1.4e-95
DOFPDPNE_01237 3.4e-41 L transposase, IS605 OrfB family
DOFPDPNE_01238 3e-37
DOFPDPNE_01239 8e-24 malY 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DOFPDPNE_01240 1.2e-20 malY 4.4.1.8 E Aminotransferase, class I
DOFPDPNE_01241 1.2e-88 malY 4.4.1.8 E Aminotransferase, class I
DOFPDPNE_01242 7.6e-55
DOFPDPNE_01243 7.7e-189 brnQ U Component of the transport system for branched-chain amino acids
DOFPDPNE_01244 1.6e-40 brnQ U Component of the transport system for branched-chain amino acids
DOFPDPNE_01245 1.1e-83 S Threonine/Serine exporter, ThrE
DOFPDPNE_01246 1.8e-139 thrE S Putative threonine/serine exporter
DOFPDPNE_01247 3.6e-293 S ABC transporter
DOFPDPNE_01248 1.9e-54
DOFPDPNE_01249 4.9e-87 rimL J Acetyltransferase (GNAT) domain
DOFPDPNE_01250 1.5e-217 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DOFPDPNE_01251 0.0 pepF E oligoendopeptidase F
DOFPDPNE_01252 1.5e-09 Z012_06740 S Fic/DOC family
DOFPDPNE_01254 1.8e-81 sip L Belongs to the 'phage' integrase family
DOFPDPNE_01255 3.1e-21
DOFPDPNE_01256 1.1e-16 S Pfam:Peptidase_M78
DOFPDPNE_01257 4.2e-32 ansR 3.4.21.88 K sequence-specific DNA binding
DOFPDPNE_01258 1.3e-18 K Helix-turn-helix XRE-family like proteins
DOFPDPNE_01259 8.1e-116 S DNA binding
DOFPDPNE_01261 1.4e-10
DOFPDPNE_01265 2.5e-57 S ERF superfamily
DOFPDPNE_01266 5.1e-60 S Conserved phage C-terminus (Phg_2220_C)
DOFPDPNE_01267 1.2e-58 S IstB-like ATP binding protein
DOFPDPNE_01269 2.2e-59 S Single-strand binding protein family
DOFPDPNE_01271 1.6e-20 K transcriptional
DOFPDPNE_01272 2e-20 K transcriptional
DOFPDPNE_01277 1.3e-23 xtmA L Terminase small subunit
DOFPDPNE_01278 4.7e-214 S Terminase RNAseH like domain
DOFPDPNE_01279 9.3e-231 S Phage portal protein, SPP1 Gp6-like
DOFPDPNE_01280 7.1e-134 S Phage minor capsid protein 2
DOFPDPNE_01281 2.3e-07 S GIY-YIG type nucleases (URI domain)
DOFPDPNE_01282 3.7e-34 S Phage minor capsid protein 2
DOFPDPNE_01283 5.6e-67 S Phage minor structural protein GP20
DOFPDPNE_01284 2.1e-167 gpG
DOFPDPNE_01285 5.1e-34
DOFPDPNE_01286 7.8e-34 S Minor capsid protein
DOFPDPNE_01287 4.1e-41 S Minor capsid protein
DOFPDPNE_01288 6.7e-35 S Minor capsid protein from bacteriophage
DOFPDPNE_01289 1.6e-85 N domain, Protein
DOFPDPNE_01290 1.1e-32
DOFPDPNE_01291 4e-73 S Bacteriophage Gp15 protein
DOFPDPNE_01292 0.0 xkdO D NLP P60 protein
DOFPDPNE_01293 1.3e-87 S phage tail
DOFPDPNE_01294 0.0 S Phage minor structural protein
DOFPDPNE_01295 1.1e-104 S Phage minor structural protein
DOFPDPNE_01299 9.6e-33
DOFPDPNE_01302 1.6e-17
DOFPDPNE_01304 4.2e-53 S Bacteriophage holin of superfamily 6 (Holin_LLH)
DOFPDPNE_01305 2.4e-124 M hydrolase, family 25
DOFPDPNE_01307 3.3e-13
DOFPDPNE_01308 2.2e-63 S PFAM Uncharacterised protein family UPF0150
DOFPDPNE_01309 9.7e-106 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DOFPDPNE_01310 6e-31 cspA K Cold shock protein
DOFPDPNE_01313 1e-95 MA20_25245 K Acetyltransferase (GNAT) domain
DOFPDPNE_01318 2.4e-66 emrY EGP Major facilitator Superfamily
DOFPDPNE_01319 3e-29
DOFPDPNE_01320 2.1e-241 pyrP F Permease
DOFPDPNE_01321 1.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DOFPDPNE_01322 8.3e-263 emrY EGP Major facilitator Superfamily
DOFPDPNE_01323 5.1e-218 mdtG EGP Major facilitator Superfamily
DOFPDPNE_01324 7.8e-210 pepA E M42 glutamyl aminopeptidase
DOFPDPNE_01325 2.2e-311 ybiT S ABC transporter, ATP-binding protein
DOFPDPNE_01326 4e-147
DOFPDPNE_01327 4.9e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
DOFPDPNE_01328 3.8e-148 glnH ET ABC transporter
DOFPDPNE_01329 5.1e-81 K Transcriptional regulator, MarR family
DOFPDPNE_01330 8.5e-291 XK27_09600 V ABC transporter, ATP-binding protein
DOFPDPNE_01331 0.0 V ABC transporter transmembrane region
DOFPDPNE_01332 1.1e-101 S ABC-type cobalt transport system, permease component
DOFPDPNE_01333 2.2e-157 EGP Major facilitator superfamily
DOFPDPNE_01334 3.9e-116 udk 2.7.1.48 F Zeta toxin
DOFPDPNE_01335 2.8e-29 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
DOFPDPNE_01336 1.5e-252 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
DOFPDPNE_01337 7.7e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
DOFPDPNE_01338 2.9e-37
DOFPDPNE_01339 3.9e-90 4.1.1.44 S Carboxymuconolactone decarboxylase family
DOFPDPNE_01340 2.9e-32 4.1.1.44 S Carboxymuconolactone decarboxylase family
DOFPDPNE_01341 1.8e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOFPDPNE_01342 7.9e-95 S LPXTG cell wall anchor motif
DOFPDPNE_01343 1.5e-92 UW LPXTG-motif cell wall anchor domain protein
DOFPDPNE_01344 1e-72
DOFPDPNE_01345 2.3e-102 yagE E amino acid
DOFPDPNE_01348 6.8e-56 S Bacteriocin helveticin-J
DOFPDPNE_01349 1.3e-185 S SLAP domain
DOFPDPNE_01350 8.4e-44 L transposase, IS605 OrfB family
DOFPDPNE_01351 1.5e-95 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
DOFPDPNE_01352 2.8e-183 P secondary active sulfate transmembrane transporter activity
DOFPDPNE_01353 5.3e-124 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
DOFPDPNE_01354 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DOFPDPNE_01355 5.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DOFPDPNE_01356 8.7e-156 ropB K Transcriptional regulator
DOFPDPNE_01357 8.9e-221 EGP Major facilitator Superfamily
DOFPDPNE_01358 5.2e-116 ropB K Transcriptional regulator
DOFPDPNE_01361 1e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DOFPDPNE_01363 3.2e-10 S cog cog1373
DOFPDPNE_01364 4e-133 K helix_turn_helix, mercury resistance
DOFPDPNE_01365 2e-231 pbuG S permease
DOFPDPNE_01366 9.7e-161 S Uncharacterised protein family (UPF0236)
DOFPDPNE_01367 1.5e-75 L Transposase
DOFPDPNE_01368 1.2e-64 L Transposase
DOFPDPNE_01371 1.2e-25 L Transposase
DOFPDPNE_01372 1.8e-26 L Transposase
DOFPDPNE_01373 1.5e-87 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DOFPDPNE_01374 6.1e-260 L Transposase IS66 family
DOFPDPNE_01375 8.2e-154 ykuT M mechanosensitive ion channel
DOFPDPNE_01376 3.3e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DOFPDPNE_01377 1e-44
DOFPDPNE_01378 4.4e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DOFPDPNE_01379 8.3e-182 ccpA K catabolite control protein A
DOFPDPNE_01380 2.7e-268 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DOFPDPNE_01381 1.1e-55
DOFPDPNE_01382 3.9e-278 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
DOFPDPNE_01383 3e-89 yutD S Protein of unknown function (DUF1027)
DOFPDPNE_01384 1.2e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DOFPDPNE_01385 4.9e-84 S Protein of unknown function (DUF1461)
DOFPDPNE_01386 1.8e-116 dedA S SNARE-like domain protein
DOFPDPNE_01387 2.5e-152 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
DOFPDPNE_01388 5.8e-112 3.6.1.27 I Acid phosphatase homologues
DOFPDPNE_01389 5.1e-105 lacA 2.3.1.79 S Transferase hexapeptide repeat
DOFPDPNE_01390 5.7e-208 pbpX1 V Beta-lactamase
DOFPDPNE_01391 5.7e-152 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DOFPDPNE_01392 4e-93 S ECF-type riboflavin transporter, S component
DOFPDPNE_01393 8.1e-232 S Putative peptidoglycan binding domain
DOFPDPNE_01394 1.7e-235 mepA V MATE efflux family protein
DOFPDPNE_01395 2.3e-256 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DOFPDPNE_01396 6.5e-34
DOFPDPNE_01397 1.4e-29 fic D Fic/DOC family
DOFPDPNE_01398 9.7e-61
DOFPDPNE_01399 9e-295 P ABC transporter
DOFPDPNE_01400 2.6e-294 V ABC-type multidrug transport system, ATPase and permease components
DOFPDPNE_01401 2.1e-68 S Putative adhesin
DOFPDPNE_01402 1.3e-58 ypaA S Protein of unknown function (DUF1304)
DOFPDPNE_01403 2.1e-89
DOFPDPNE_01404 2.4e-56
DOFPDPNE_01405 2.9e-116 S Fic/DOC family
DOFPDPNE_01406 1.7e-102
DOFPDPNE_01407 6.1e-208 EGP Major facilitator Superfamily
DOFPDPNE_01408 5.4e-135
DOFPDPNE_01409 5.3e-79
DOFPDPNE_01410 2.8e-159 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DOFPDPNE_01411 2.9e-160 dnaQ 2.7.7.7 L EXOIII
DOFPDPNE_01412 5e-159 endA F DNA RNA non-specific endonuclease
DOFPDPNE_01413 1.6e-282 pipD E Dipeptidase
DOFPDPNE_01414 2.4e-203 malK P ATPases associated with a variety of cellular activities
DOFPDPNE_01415 1.9e-158 gtsB P ABC-type sugar transport systems, permease components
DOFPDPNE_01416 4.7e-146 gtsC P Binding-protein-dependent transport system inner membrane component
DOFPDPNE_01417 1.7e-256 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
DOFPDPNE_01418 1.1e-242 G Bacterial extracellular solute-binding protein
DOFPDPNE_01419 7.4e-161 corA P CorA-like Mg2+ transporter protein
DOFPDPNE_01420 5.5e-159 3.5.2.6 V Beta-lactamase enzyme family
DOFPDPNE_01421 5.6e-98 yobS K Bacterial regulatory proteins, tetR family
DOFPDPNE_01422 0.0 ydgH S MMPL family
DOFPDPNE_01423 7.8e-159
DOFPDPNE_01424 3.9e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
DOFPDPNE_01425 2e-126 hipB K Helix-turn-helix
DOFPDPNE_01427 3.4e-154 I alpha/beta hydrolase fold
DOFPDPNE_01428 1.8e-110 yjbF S SNARE associated Golgi protein
DOFPDPNE_01429 1.1e-98 J Acetyltransferase (GNAT) domain
DOFPDPNE_01430 5.9e-252 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DOFPDPNE_01431 1.8e-206 pbpX1 V Beta-lactamase
DOFPDPNE_01432 6.4e-107 3.6.1.55 F NUDIX domain
DOFPDPNE_01433 9.9e-302 I Protein of unknown function (DUF2974)
DOFPDPNE_01434 2.3e-17 C FMN_bind
DOFPDPNE_01435 1.7e-82
DOFPDPNE_01436 8e-179 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
DOFPDPNE_01437 1.2e-68 S Aldo keto reductase
DOFPDPNE_01438 6.8e-89 S Aldo keto reductase
DOFPDPNE_01439 4.3e-82 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFPDPNE_01440 3.3e-121 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFPDPNE_01441 2e-32 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFPDPNE_01442 2.1e-117 K UTRA domain
DOFPDPNE_01443 1.8e-70 yeaL S Protein of unknown function (DUF441)
DOFPDPNE_01444 2.7e-10
DOFPDPNE_01445 7.3e-147 cbiQ P cobalt transport
DOFPDPNE_01446 0.0 ykoD P ABC transporter, ATP-binding protein
DOFPDPNE_01447 4.3e-95 S UPF0397 protein
DOFPDPNE_01448 2.2e-66 S Domain of unknown function DUF1828
DOFPDPNE_01449 4.7e-16
DOFPDPNE_01450 3.8e-54
DOFPDPNE_01451 3.3e-180 citR K Putative sugar-binding domain
DOFPDPNE_01452 3.1e-248 yjjP S Putative threonine/serine exporter
DOFPDPNE_01453 1e-92 yxkA S Phosphatidylethanolamine-binding protein
DOFPDPNE_01454 3.3e-52 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DOFPDPNE_01455 1.1e-33 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DOFPDPNE_01456 3.3e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DOFPDPNE_01457 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
DOFPDPNE_01458 1.5e-59
DOFPDPNE_01459 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOFPDPNE_01460 5.1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DOFPDPNE_01461 3.1e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
DOFPDPNE_01462 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DOFPDPNE_01463 3e-223 patA 2.6.1.1 E Aminotransferase
DOFPDPNE_01464 2.2e-40
DOFPDPNE_01465 2.6e-140 purD 6.3.4.13 F Belongs to the GARS family
DOFPDPNE_01466 4.7e-224 L Transposase
DOFPDPNE_01467 7.5e-123 darA C Flavodoxin
DOFPDPNE_01469 3.6e-288 V ABC transporter transmembrane region
DOFPDPNE_01470 3.2e-118 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
DOFPDPNE_01473 2.6e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
DOFPDPNE_01474 1.4e-89 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DOFPDPNE_01475 5.7e-80 ntd 2.4.2.6 F Nucleoside
DOFPDPNE_01476 0.0 G Belongs to the glycosyl hydrolase 31 family
DOFPDPNE_01477 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DOFPDPNE_01478 2.2e-108 vanZ V VanZ like family
DOFPDPNE_01479 6.4e-262 pgi 5.3.1.9 G Belongs to the GPI family
DOFPDPNE_01480 7.8e-67 EGP Major facilitator Superfamily
DOFPDPNE_01481 6.1e-112 EGP Major facilitator Superfamily
DOFPDPNE_01482 2.2e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DOFPDPNE_01483 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DOFPDPNE_01484 5.6e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DOFPDPNE_01485 6.4e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOFPDPNE_01486 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DOFPDPNE_01487 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DOFPDPNE_01488 5.2e-259 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DOFPDPNE_01489 3.9e-196 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DOFPDPNE_01490 1.3e-34 yaaA S S4 domain protein YaaA
DOFPDPNE_01491 1.6e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DOFPDPNE_01492 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOFPDPNE_01493 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOFPDPNE_01494 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
DOFPDPNE_01495 3.1e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DOFPDPNE_01496 3.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DOFPDPNE_01497 8.8e-47
DOFPDPNE_01498 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DOFPDPNE_01499 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DOFPDPNE_01500 2.2e-241 cycA E Amino acid permease
DOFPDPNE_01501 1.6e-88 maa S transferase hexapeptide repeat
DOFPDPNE_01502 2.1e-68 K Transcriptional regulator
DOFPDPNE_01503 5.6e-62 K Transcriptional regulator
DOFPDPNE_01504 7.6e-64 manO S Domain of unknown function (DUF956)
DOFPDPNE_01505 1.5e-174 manN G system, mannose fructose sorbose family IID component
DOFPDPNE_01506 8.1e-135 manY G PTS system
DOFPDPNE_01507 7.9e-188 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
DOFPDPNE_01508 5.7e-65 rafA 3.2.1.22 G alpha-galactosidase
DOFPDPNE_01509 8.5e-123 rafA 3.2.1.22 G alpha-galactosidase
DOFPDPNE_01510 2.8e-39 rafA 3.2.1.22 G alpha-galactosidase
DOFPDPNE_01511 5.1e-50 G phosphoenolpyruvate-dependent sugar phosphotransferase system
DOFPDPNE_01512 2.7e-29 scrB 3.2.1.26 GH32 G invertase
DOFPDPNE_01513 2e-160 msmR7 K helix_turn_helix, arabinose operon control protein
DOFPDPNE_01514 5e-69 yslB S Protein of unknown function (DUF2507)
DOFPDPNE_01515 1.8e-147 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DOFPDPNE_01516 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DOFPDPNE_01517 5.8e-97 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DOFPDPNE_01518 2.1e-226 S response to antibiotic
DOFPDPNE_01519 8.2e-93
DOFPDPNE_01520 1.3e-25
DOFPDPNE_01521 1.7e-104
DOFPDPNE_01522 1.6e-174 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
DOFPDPNE_01523 1.8e-37 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
DOFPDPNE_01524 1e-63 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
DOFPDPNE_01525 1.1e-145 K SIS domain
DOFPDPNE_01526 1.6e-166 yufQ S Belongs to the binding-protein-dependent transport system permease family
DOFPDPNE_01527 2.3e-199 yufP S Belongs to the binding-protein-dependent transport system permease family
DOFPDPNE_01528 2.1e-285 xylG 3.6.3.17 S ABC transporter
DOFPDPNE_01529 6e-186 tcsA S ABC transporter substrate-binding protein PnrA-like
DOFPDPNE_01530 7.1e-49 S Uncharacterised protein family (UPF0236)
DOFPDPNE_01531 1.3e-157 S Uncharacterised protein family (UPF0236)
DOFPDPNE_01532 3.4e-217 naiP EGP Major facilitator Superfamily
DOFPDPNE_01533 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
DOFPDPNE_01534 1e-25 oppA E ABC transporter
DOFPDPNE_01535 4.5e-239 oppA E ABC transporter
DOFPDPNE_01536 8.9e-118 Q Imidazolonepropionase and related amidohydrolases
DOFPDPNE_01537 3.7e-105 Q Imidazolonepropionase and related amidohydrolases
DOFPDPNE_01540 2.3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DOFPDPNE_01541 4.3e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DOFPDPNE_01542 7e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
DOFPDPNE_01543 4.2e-69 S SLAP domain
DOFPDPNE_01544 5.9e-180 S ABC transporter
DOFPDPNE_01545 7.7e-110 S ABC-2 family transporter protein
DOFPDPNE_01546 8.8e-142 S ABC-2 family transporter protein
DOFPDPNE_01548 1.6e-229 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
DOFPDPNE_01549 1.3e-128 XK27_08435 K UTRA
DOFPDPNE_01551 8.6e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DOFPDPNE_01552 1.4e-206 csaB M Glycosyl transferases group 1
DOFPDPNE_01553 1e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DOFPDPNE_01554 2.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DOFPDPNE_01555 2.7e-160
DOFPDPNE_01556 1.1e-66 L Transposase
DOFPDPNE_01557 1.2e-25 L Transposase
DOFPDPNE_01558 2e-43 S Uncharacterised protein family (UPF0236)
DOFPDPNE_01559 3.2e-242 amtB P ammonium transporter
DOFPDPNE_01560 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
DOFPDPNE_01561 5.1e-38 ynzC S UPF0291 protein
DOFPDPNE_01562 2.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DOFPDPNE_01563 2.5e-149 E GDSL-like Lipase/Acylhydrolase family
DOFPDPNE_01564 6.4e-122 ung2 3.2.2.27 L Uracil-DNA glycosylase
DOFPDPNE_01565 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DOFPDPNE_01566 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DOFPDPNE_01567 1.5e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DOFPDPNE_01568 4.5e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DOFPDPNE_01569 6.4e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DOFPDPNE_01570 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DOFPDPNE_01571 6.4e-193 L Transposase and inactivated derivatives, IS30 family
DOFPDPNE_01572 1.4e-259 yfnA E amino acid
DOFPDPNE_01573 5.2e-44
DOFPDPNE_01574 7.2e-288 pipD E Dipeptidase
DOFPDPNE_01575 9.6e-89 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DOFPDPNE_01576 0.0 smc D Required for chromosome condensation and partitioning
DOFPDPNE_01577 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DOFPDPNE_01578 0.0 oppA E ABC transporter substrate-binding protein
DOFPDPNE_01579 7e-243 S Uncharacterised protein family (UPF0236)
DOFPDPNE_01580 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DOFPDPNE_01581 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DOFPDPNE_01582 2.3e-29 secG U Preprotein translocase
DOFPDPNE_01583 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DOFPDPNE_01584 3.7e-177 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOFPDPNE_01585 8.9e-203 cpoA GT4 M Glycosyltransferase, group 1 family protein
DOFPDPNE_01586 4.8e-221 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
DOFPDPNE_01614 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
DOFPDPNE_01615 8.4e-36 L IS1381, transposase OrfA
DOFPDPNE_01616 2.1e-246 3.5.1.47 S Peptidase dimerisation domain
DOFPDPNE_01617 1e-140 S Protein of unknown function (DUF3100)
DOFPDPNE_01618 1.3e-82 S An automated process has identified a potential problem with this gene model
DOFPDPNE_01619 1.5e-25 WQ51_00220 K Helix-turn-helix XRE-family like proteins
DOFPDPNE_01621 2.4e-127 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DOFPDPNE_01622 2e-109 eno2 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DOFPDPNE_01624 2.9e-120 yhiD S MgtC family
DOFPDPNE_01625 2.2e-240 I Protein of unknown function (DUF2974)
DOFPDPNE_01626 3.3e-37
DOFPDPNE_01628 7.2e-146 scrK 2.7.1.2, 2.7.1.4 GK ROK family
DOFPDPNE_01629 8.3e-176 degV S DegV family
DOFPDPNE_01631 2.3e-26 L Transposase
DOFPDPNE_01632 1.8e-22 L Transposase
DOFPDPNE_01633 8.1e-243 purD 6.3.4.13 F Belongs to the GARS family
DOFPDPNE_01634 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DOFPDPNE_01635 4.9e-201 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DOFPDPNE_01636 2.4e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DOFPDPNE_01637 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOFPDPNE_01638 8.8e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOFPDPNE_01639 1.3e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOFPDPNE_01640 3.9e-133 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DOFPDPNE_01641 1.5e-219 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DOFPDPNE_01642 1.3e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DOFPDPNE_01643 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DOFPDPNE_01644 9e-19 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DOFPDPNE_01645 6.4e-96 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DOFPDPNE_01646 8e-205 ydiM G Major Facilitator Superfamily
DOFPDPNE_01647 2e-160 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DOFPDPNE_01648 8.8e-97 L DDE superfamily endonuclease
DOFPDPNE_01649 1.7e-66
DOFPDPNE_01650 1.5e-40
DOFPDPNE_01651 7.4e-37 glvR K Helix-turn-helix domain, rpiR family
DOFPDPNE_01652 7.1e-189 ansA 3.5.1.1 EJ L-asparaginase, type I
DOFPDPNE_01653 3.2e-15
DOFPDPNE_01654 8.2e-125
DOFPDPNE_01655 3.1e-242 S response to antibiotic
DOFPDPNE_01656 1.7e-134 cysA V ABC transporter, ATP-binding protein
DOFPDPNE_01657 0.0 V FtsX-like permease family
DOFPDPNE_01658 2.3e-91 yitS S Uncharacterised protein, DegV family COG1307
DOFPDPNE_01659 3.4e-29 yitS S Uncharacterised protein, DegV family COG1307
DOFPDPNE_01660 3.6e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DOFPDPNE_01662 1.6e-85 C nitroreductase
DOFPDPNE_01663 7.7e-11 ypbG 2.7.1.2 GK ROK family
DOFPDPNE_01664 7e-81 ypbG 2.7.1.2 GK ROK family
DOFPDPNE_01665 1.2e-282 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DOFPDPNE_01666 1.7e-136 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOFPDPNE_01667 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DOFPDPNE_01668 1.4e-242 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DOFPDPNE_01669 0.0 oatA I Acyltransferase
DOFPDPNE_01670 2.4e-178 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DOFPDPNE_01671 5.5e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DOFPDPNE_01672 6.2e-33 yrvD S Lipopolysaccharide assembly protein A domain
DOFPDPNE_01673 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DOFPDPNE_01674 9.8e-160 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
DOFPDPNE_01675 2.5e-22 S Protein of unknown function (DUF2929)
DOFPDPNE_01676 0.0 dnaE 2.7.7.7 L DNA polymerase
DOFPDPNE_01677 6.6e-184 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DOFPDPNE_01678 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DOFPDPNE_01679 6.5e-170 cvfB S S1 domain
DOFPDPNE_01680 4e-167 xerD D recombinase XerD
DOFPDPNE_01681 4.9e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOFPDPNE_01682 2.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DOFPDPNE_01683 2.4e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DOFPDPNE_01684 8.5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DOFPDPNE_01685 1e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DOFPDPNE_01686 5.3e-30 yocH M Lysin motif
DOFPDPNE_01687 3.8e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DOFPDPNE_01688 1.3e-208 rpsA 1.17.7.4 J Ribosomal protein S1
DOFPDPNE_01689 2.8e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DOFPDPNE_01690 3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DOFPDPNE_01691 2.3e-229 S Tetratricopeptide repeat protein
DOFPDPNE_01692 4.2e-161 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DOFPDPNE_01693 1.7e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DOFPDPNE_01694 1.1e-113 hlyIII S protein, hemolysin III
DOFPDPNE_01695 7.7e-149 DegV S Uncharacterised protein, DegV family COG1307
DOFPDPNE_01696 9.3e-36 yozE S Belongs to the UPF0346 family
DOFPDPNE_01697 3.1e-279 yjcE P Sodium proton antiporter
DOFPDPNE_01698 1.3e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DOFPDPNE_01699 3.7e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOFPDPNE_01700 1.1e-155 dprA LU DNA protecting protein DprA
DOFPDPNE_01701 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOFPDPNE_01702 9.4e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DOFPDPNE_01703 1.3e-168 xerC D Phage integrase, N-terminal SAM-like domain
DOFPDPNE_01704 3e-90 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DOFPDPNE_01705 7.7e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DOFPDPNE_01706 7.3e-177 lacX 5.1.3.3 G Aldose 1-epimerase
DOFPDPNE_01707 1.8e-34 L COG2826 Transposase and inactivated derivatives, IS30 family
DOFPDPNE_01709 3.6e-151 xerD L Phage integrase, N-terminal SAM-like domain
DOFPDPNE_01710 1.6e-106 K DNA-binding helix-turn-helix protein
DOFPDPNE_01711 1.4e-147 L Probable transposase
DOFPDPNE_01712 1.1e-126 pgm3 G Phosphoglycerate mutase family
DOFPDPNE_01713 1.7e-125 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
DOFPDPNE_01714 0.0 helD 3.6.4.12 L DNA helicase
DOFPDPNE_01715 3.2e-26
DOFPDPNE_01716 4.5e-34
DOFPDPNE_01717 5.5e-80 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
DOFPDPNE_01718 4e-170 yobV1 K WYL domain
DOFPDPNE_01719 5.3e-68 S pyridoxamine 5-phosphate
DOFPDPNE_01720 4.2e-261 npr 1.11.1.1 C NADH oxidase
DOFPDPNE_01721 1.2e-58 K Transcriptional regulator
DOFPDPNE_01722 8.5e-48 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
DOFPDPNE_01723 5.3e-66 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
DOFPDPNE_01724 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
DOFPDPNE_01725 3.6e-32 copZ C Heavy-metal-associated domain
DOFPDPNE_01726 1e-88 dps P Belongs to the Dps family
DOFPDPNE_01727 1.2e-109 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
DOFPDPNE_01728 4e-32 K Acetyltransferase (GNAT) family
DOFPDPNE_01729 2.7e-94 L Belongs to the 'phage' integrase family
DOFPDPNE_01734 7.5e-43
DOFPDPNE_01735 3.5e-93 3.4.21.88 K Peptidase S24-like
DOFPDPNE_01736 4.1e-31 S Archaea bacterial proteins of unknown function
DOFPDPNE_01737 3.7e-66 S ASCH domain
DOFPDPNE_01738 2.2e-140 L restriction endonuclease
DOFPDPNE_01739 9.6e-155 L helicase
DOFPDPNE_01740 2.3e-301 hsdM 2.1.1.72 V type I restriction-modification system
DOFPDPNE_01741 4.1e-98 3.1.21.3 V Type I restriction modification DNA specificity domain
DOFPDPNE_01742 3.6e-285 lsa S ABC transporter
DOFPDPNE_01743 1.8e-69 L Transposase
DOFPDPNE_01744 7.9e-291 V ABC transporter transmembrane region
DOFPDPNE_01745 9.5e-38 KLT serine threonine protein kinase
DOFPDPNE_01746 1e-290 V ABC transporter transmembrane region
DOFPDPNE_01747 1.4e-37
DOFPDPNE_01748 4e-43
DOFPDPNE_01749 1.3e-134 CP ATPases associated with a variety of cellular activities
DOFPDPNE_01750 2e-124 V Transport permease protein
DOFPDPNE_01751 8.2e-93 V Transport permease protein
DOFPDPNE_01752 4.3e-27
DOFPDPNE_01753 1.1e-54 4.4.1.5 E lactoylglutathione lyase activity
DOFPDPNE_01754 1.2e-64 S ASCH domain
DOFPDPNE_01755 5.4e-109 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DOFPDPNE_01756 4.7e-81
DOFPDPNE_01757 2.1e-304
DOFPDPNE_01758 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
DOFPDPNE_01759 1.8e-130 treR K UTRA
DOFPDPNE_01760 0.0 treB G phosphotransferase system
DOFPDPNE_01761 3.5e-63 L IS1381, transposase OrfA
DOFPDPNE_01764 2e-21
DOFPDPNE_01765 9.2e-220 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DOFPDPNE_01766 5.6e-155 S reductase
DOFPDPNE_01767 1.1e-84 yxeH S hydrolase
DOFPDPNE_01768 9.6e-46 yxeH S hydrolase
DOFPDPNE_01769 7.8e-16 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFPDPNE_01770 2.1e-33 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFPDPNE_01771 3.3e-43 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOFPDPNE_01772 9e-251 yfnA E Amino Acid
DOFPDPNE_01773 6.2e-108 dedA 3.1.3.1 S SNARE associated Golgi protein
DOFPDPNE_01774 1.9e-07 L COG2963 Transposase and inactivated derivatives
DOFPDPNE_01775 2.8e-157 L COG2963 Transposase and inactivated derivatives
DOFPDPNE_01776 3.6e-16 L COG2826 Transposase and inactivated derivatives, IS30 family
DOFPDPNE_01777 8.6e-98
DOFPDPNE_01778 2.1e-32 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
DOFPDPNE_01779 2.8e-36 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
DOFPDPNE_01780 9.5e-172 mrr L restriction endonuclease
DOFPDPNE_01781 1.3e-34 L An automated process has identified a potential problem with this gene model
DOFPDPNE_01782 1.9e-132 cobQ S glutamine amidotransferase
DOFPDPNE_01783 2.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DOFPDPNE_01784 4.6e-59 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DOFPDPNE_01785 8.7e-63 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DOFPDPNE_01786 5.9e-69 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DOFPDPNE_01787 1.5e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
DOFPDPNE_01788 8e-160 V ABC-type multidrug transport system, ATPase and permease components
DOFPDPNE_01789 3.4e-286 V ABC-type multidrug transport system, ATPase and permease components
DOFPDPNE_01791 5.7e-16 L PFAM IS66 Orf2 family protein
DOFPDPNE_01792 1.2e-08
DOFPDPNE_01793 3.3e-14 S Phage derived protein Gp49-like (DUF891)
DOFPDPNE_01794 1.5e-40 K Helix-turn-helix XRE-family like proteins
DOFPDPNE_01795 5.3e-43
DOFPDPNE_01796 7.2e-55 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
DOFPDPNE_01797 2e-27 L Probable transposase
DOFPDPNE_01798 2.6e-109 L Probable transposase
DOFPDPNE_01799 5.1e-15 S Fic/DOC family
DOFPDPNE_01800 6.9e-251 copB 3.6.3.4 P P-type ATPase
DOFPDPNE_01801 3.1e-72 mdt(A) EGP Major facilitator Superfamily
DOFPDPNE_01802 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DOFPDPNE_01803 4.5e-82 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
DOFPDPNE_01804 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
DOFPDPNE_01806 7.1e-175 V ABC transporter transmembrane region
DOFPDPNE_01807 2.5e-247 S Uncharacterised protein family (UPF0236)
DOFPDPNE_01808 3.6e-16 L COG2826 Transposase and inactivated derivatives, IS30 family
DOFPDPNE_01809 5.9e-63 L COG2826 Transposase and inactivated derivatives, IS30 family
DOFPDPNE_01810 1.1e-46 S ACT domain
DOFPDPNE_01811 1e-105 S Domain of unknown function (DUF389)
DOFPDPNE_01812 8.1e-57 S Domain of unknown function (DUF389)
DOFPDPNE_01813 1.3e-59 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
DOFPDPNE_01814 6.8e-237 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
DOFPDPNE_01815 1.5e-56 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DOFPDPNE_01816 6.2e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DOFPDPNE_01817 5.1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DOFPDPNE_01818 1.3e-93 yqeG S HAD phosphatase, family IIIA
DOFPDPNE_01819 2.9e-212 yqeH S Ribosome biogenesis GTPase YqeH
DOFPDPNE_01820 9.8e-110 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DOFPDPNE_01821 8.6e-110 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
DOFPDPNE_01822 6.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DOFPDPNE_01823 3.9e-215 ylbM S Belongs to the UPF0348 family
DOFPDPNE_01824 4.6e-97 yceD S Uncharacterized ACR, COG1399
DOFPDPNE_01825 3.2e-127 K response regulator
DOFPDPNE_01826 8.7e-279 arlS 2.7.13.3 T Histidine kinase
DOFPDPNE_01827 8e-244 slpX S SLAP domain
DOFPDPNE_01828 2.7e-56 L Integrase
DOFPDPNE_01829 8.4e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOFPDPNE_01830 2.9e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOFPDPNE_01831 2.5e-83 racA K Domain of unknown function (DUF1836)
DOFPDPNE_01832 1.6e-154 yitS S EDD domain protein, DegV family
DOFPDPNE_01835 1.1e-62 S Protein of unknown function (DUF2974)
DOFPDPNE_01836 4.7e-109 glnP P ABC transporter permease
DOFPDPNE_01837 3e-108 gluC P ABC transporter permease
DOFPDPNE_01838 1.5e-152 glnH ET ABC transporter substrate-binding protein
DOFPDPNE_01839 2.5e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOFPDPNE_01841 9.1e-51 L Transposase
DOFPDPNE_01842 7.3e-66 M Glycosyltransferase like family 2
DOFPDPNE_01843 2.8e-143 S Membrane protein involved in the export of O-antigen and teichoic acid
DOFPDPNE_01844 8.7e-87 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DOFPDPNE_01845 8.2e-133 S KAP family P-loop domain
DOFPDPNE_01846 2.9e-142 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DOFPDPNE_01847 3.4e-102 L reverse transcriptase
DOFPDPNE_01850 1.6e-126 L An automated process has identified a potential problem with this gene model
DOFPDPNE_01851 2e-10 K response regulator
DOFPDPNE_01852 4.5e-56 K response regulator
DOFPDPNE_01853 9.4e-41 sptS 2.7.13.3 T Histidine kinase
DOFPDPNE_01854 6.3e-56 sptS 2.7.13.3 T Histidine kinase
DOFPDPNE_01855 1e-210 EGP Major facilitator Superfamily
DOFPDPNE_01856 3.7e-72 O OsmC-like protein
DOFPDPNE_01857 3.7e-128 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
DOFPDPNE_01858 2.7e-99
DOFPDPNE_01859 3.6e-118 L Transposase
DOFPDPNE_01860 2.1e-62 L Transposase
DOFPDPNE_01861 6.1e-114 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DOFPDPNE_01862 5.5e-53
DOFPDPNE_01863 9.4e-80 K Acetyltransferase (GNAT) domain
DOFPDPNE_01864 3e-119 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DOFPDPNE_01865 1.7e-78 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DOFPDPNE_01867 3.8e-08 L Transposase
DOFPDPNE_01868 2e-166 S SLAP domain
DOFPDPNE_01869 1.5e-135
DOFPDPNE_01870 3.9e-196 S SLAP domain
DOFPDPNE_01871 5.6e-146 arbV 2.3.1.51 I Acyl-transferase
DOFPDPNE_01872 2.5e-65
DOFPDPNE_01873 3.2e-147 K Helix-turn-helix domain
DOFPDPNE_01874 4.1e-158 arbx M Glycosyl transferase family 8
DOFPDPNE_01875 2.8e-187 arbY M Glycosyl transferase family 8
DOFPDPNE_01876 3.7e-10 arbY M Glycosyl transferase family 8
DOFPDPNE_01877 8.8e-161 arbY M Glycosyl transferase family 8
DOFPDPNE_01878 2.3e-167 arbZ I Phosphate acyltransferases
DOFPDPNE_01879 4.4e-35 S Cytochrome b5
DOFPDPNE_01880 1.1e-115 K Transcriptional regulator, LysR family
DOFPDPNE_01881 5.1e-63 K LysR substrate binding domain
DOFPDPNE_01882 2e-41 K LysR substrate binding domain
DOFPDPNE_01883 6.9e-19 brnQ E Component of the transport system for branched-chain amino acids
DOFPDPNE_01884 9.7e-83 S Domain of unknown function (DUF5067)
DOFPDPNE_01885 4.8e-63
DOFPDPNE_01887 3.5e-120 XK27_07525 3.6.1.55 F NUDIX domain
DOFPDPNE_01888 4e-144 2.4.2.3 F Phosphorylase superfamily
DOFPDPNE_01889 4.9e-75 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
DOFPDPNE_01891 1.3e-141 qmcA O prohibitin homologues
DOFPDPNE_01892 4.3e-52 L RelB antitoxin
DOFPDPNE_01893 3.1e-14
DOFPDPNE_01894 4.2e-194 S Bacteriocin helveticin-J
DOFPDPNE_01895 4.3e-291 M Peptidase family M1 domain
DOFPDPNE_01896 2.3e-176 S SLAP domain
DOFPDPNE_01897 2.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DOFPDPNE_01898 3e-75 S Psort location Cytoplasmic, score
DOFPDPNE_01899 3e-07 S protein conserved in bacteria
DOFPDPNE_01901 2.9e-32 S Uncharacterised protein family (UPF0236)
DOFPDPNE_01902 5.8e-122 S Uncharacterised protein family (UPF0236)
DOFPDPNE_01903 5.1e-264
DOFPDPNE_01904 3.3e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOFPDPNE_01905 7.3e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DOFPDPNE_01906 1e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DOFPDPNE_01907 1.4e-215 ecsB U ABC transporter
DOFPDPNE_01908 3.9e-136 ecsA V ABC transporter, ATP-binding protein
DOFPDPNE_01909 3.8e-54 higA K Helix-turn-helix XRE-family like proteins
DOFPDPNE_01910 7e-36 S Plasmid maintenance system killer
DOFPDPNE_01911 3.1e-80 hit FG Scavenger mRNA decapping enzyme C-term binding
DOFPDPNE_01912 8e-28
DOFPDPNE_01913 2.4e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DOFPDPNE_01914 6.2e-78 S PAS domain
DOFPDPNE_01915 3.4e-188 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
DOFPDPNE_01916 0.0 L AAA domain
DOFPDPNE_01917 2.4e-231 yhaO L Ser Thr phosphatase family protein
DOFPDPNE_01918 9.4e-56 yheA S Belongs to the UPF0342 family
DOFPDPNE_01919 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DOFPDPNE_01920 6.7e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOFPDPNE_01921 1.4e-21 bglH 3.2.1.86 GT1 G beta-glucosidase activity
DOFPDPNE_01922 4.5e-77 mgtC S MgtC family
DOFPDPNE_01923 8.3e-31 mgtC S MgtC family
DOFPDPNE_01924 4.5e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DOFPDPNE_01925 9.8e-55
DOFPDPNE_01926 3.1e-150 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DOFPDPNE_01927 1.2e-20 UW LPXTG-motif cell wall anchor domain protein
DOFPDPNE_01928 1.8e-136 L Transposase
DOFPDPNE_01929 1.6e-87
DOFPDPNE_01930 3.5e-266 S Archaea bacterial proteins of unknown function
DOFPDPNE_01931 0.0 yeeA V Type II restriction enzyme, methylase subunits
DOFPDPNE_01932 1.3e-115
DOFPDPNE_01933 0.0 yeeB L DEAD-like helicases superfamily
DOFPDPNE_01934 1.9e-183 pstS P T5orf172
DOFPDPNE_01936 4.7e-302 XK27_11280 S Psort location CytoplasmicMembrane, score
DOFPDPNE_01937 1.9e-153 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOFPDPNE_01938 7.3e-88 pepO 3.4.24.71 O Peptidase family M13
DOFPDPNE_01939 3.3e-59 pdxH S Pyridoxamine 5'-phosphate oxidase
DOFPDPNE_01940 8.1e-233 steT E amino acid
DOFPDPNE_01941 6.4e-40 S Uncharacterised protein family (UPF0236)
DOFPDPNE_01942 3.4e-230 amd 3.5.1.47 E Peptidase family M20/M25/M40
DOFPDPNE_01943 9e-173 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
DOFPDPNE_01944 5.1e-179 mmuP E amino acid
DOFPDPNE_01945 7.8e-34 mmuP E amino acid
DOFPDPNE_01946 8.1e-243 N Uncharacterized conserved protein (DUF2075)
DOFPDPNE_01947 3.4e-26 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
DOFPDPNE_01948 3e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DOFPDPNE_01949 2.7e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DOFPDPNE_01950 2e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DOFPDPNE_01951 6.8e-25
DOFPDPNE_01952 2.3e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DOFPDPNE_01953 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DOFPDPNE_01954 2.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DOFPDPNE_01955 2.6e-134 comFC S Competence protein
DOFPDPNE_01956 1.1e-247 comFA L Helicase C-terminal domain protein
DOFPDPNE_01957 2.1e-117 yvyE 3.4.13.9 S YigZ family
DOFPDPNE_01958 1.4e-209 tagO 2.7.8.33, 2.7.8.35 M transferase
DOFPDPNE_01959 3.6e-219 rny S Endoribonuclease that initiates mRNA decay
DOFPDPNE_01960 2.5e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DOFPDPNE_01961 1.9e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOFPDPNE_01962 6.8e-132 ymfM S Helix-turn-helix domain
DOFPDPNE_01963 1e-133 IQ Enoyl-(Acyl carrier protein) reductase
DOFPDPNE_01964 1e-237 S Peptidase M16
DOFPDPNE_01965 3.5e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
DOFPDPNE_01966 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
DOFPDPNE_01967 1.4e-68 WQ51_03320 S Protein of unknown function (DUF1149)
DOFPDPNE_01968 5.5e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DOFPDPNE_01969 4.9e-213 yubA S AI-2E family transporter
DOFPDPNE_01970 8.7e-35 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
DOFPDPNE_01971 1.6e-22 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
DOFPDPNE_01972 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
DOFPDPNE_01973 1.8e-55 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
DOFPDPNE_01974 3e-122 gntR1 K UTRA
DOFPDPNE_01975 4.9e-199
DOFPDPNE_01978 1.8e-93
DOFPDPNE_01980 1.3e-111 pfoS S Phosphotransferase system, EIIC
DOFPDPNE_01981 1.5e-19 pfoS S Phosphotransferase system, EIIC
DOFPDPNE_01983 4e-33 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DOFPDPNE_01984 6.5e-54 eutP E Ethanolamine utilisation - propanediol utilisation
DOFPDPNE_01985 1.5e-44 U FFAT motif binding
DOFPDPNE_01986 8.8e-85 U FFAT motif binding
DOFPDPNE_01987 8.7e-125 S ECF-type riboflavin transporter, S component
DOFPDPNE_01988 0.0 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
DOFPDPNE_01989 1.2e-155 P ABC-type cobalt transport system permease component CbiQ and related transporters
DOFPDPNE_01991 4.2e-264 S Uncharacterised protein family (UPF0236)
DOFPDPNE_01992 1.1e-291 S Domain of unknown function (DUF4430)
DOFPDPNE_01993 2.7e-183 U FFAT motif binding
DOFPDPNE_01994 4.8e-81 S Domain of unknown function (DUF4430)
DOFPDPNE_01995 7.5e-15 NU Mycoplasma protein of unknown function, DUF285
DOFPDPNE_01996 9.6e-258 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
DOFPDPNE_01997 8.3e-23
DOFPDPNE_01998 6.2e-171 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DOFPDPNE_01999 4.7e-96 ywnH 2.3.1.183 M acetyltransferase (GNAT) family
DOFPDPNE_02000 2.2e-15 K Penicillinase repressor
DOFPDPNE_02001 4.4e-94 copB 3.6.3.4 P P-type ATPase
DOFPDPNE_02002 6.8e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
DOFPDPNE_02003 7.6e-211 yceI EGP Major facilitator Superfamily
DOFPDPNE_02004 6.4e-97 L Transposase and inactivated derivatives, IS30 family
DOFPDPNE_02005 2.7e-222 oxlT P Major Facilitator Superfamily
DOFPDPNE_02006 4.5e-23 L Helix-turn-helix domain
DOFPDPNE_02007 5.5e-41 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
DOFPDPNE_02008 7.1e-155 S hydrolase
DOFPDPNE_02009 1.1e-63 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DOFPDPNE_02010 4.2e-81 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DOFPDPNE_02011 7.8e-100 3.6.1.27 I Acid phosphatase homologues
DOFPDPNE_02012 3.2e-36 L An automated process has identified a potential problem with this gene model
DOFPDPNE_02014 3.4e-52 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DOFPDPNE_02015 2.7e-140 S Uncharacterized protein conserved in bacteria (DUF2263)
DOFPDPNE_02016 5.1e-60
DOFPDPNE_02017 4.6e-16 lhr L DEAD DEAH box helicase
DOFPDPNE_02018 5.5e-115 L transposase, IS605 OrfB family
DOFPDPNE_02019 2.5e-127 G Peptidase_C39 like family
DOFPDPNE_02020 1.4e-66 M NlpC/P60 family
DOFPDPNE_02021 8.4e-51 M NlpC/P60 family
DOFPDPNE_02022 2.6e-38
DOFPDPNE_02024 2.7e-67
DOFPDPNE_02025 1.1e-55 S Iron-sulfur cluster assembly protein
DOFPDPNE_02026 2.6e-147 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DOFPDPNE_02027 3.1e-124 sdaAB 4.3.1.17 E Serine dehydratase beta chain
DOFPDPNE_02028 5.2e-23
DOFPDPNE_02029 7.2e-49
DOFPDPNE_02030 1.2e-209 G Major Facilitator Superfamily
DOFPDPNE_02031 0.0 3.6.3.8 P P-type ATPase
DOFPDPNE_02032 1.1e-113 yufQ S Belongs to the binding-protein-dependent transport system permease family
DOFPDPNE_02033 2.5e-27 yufQ S Belongs to the binding-protein-dependent transport system permease family
DOFPDPNE_02034 1.4e-21 yufP S Belongs to the binding-protein-dependent transport system permease family
DOFPDPNE_02035 1.7e-42 yufP L Belongs to the binding-protein-dependent transport system permease family
DOFPDPNE_02036 1.2e-32 S RelB antitoxin
DOFPDPNE_02037 1e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DOFPDPNE_02038 5.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DOFPDPNE_02039 2.2e-168 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DOFPDPNE_02040 3.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DOFPDPNE_02041 9.4e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DOFPDPNE_02042 3.2e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DOFPDPNE_02043 1.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DOFPDPNE_02044 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
DOFPDPNE_02045 4e-24 L An automated process has identified a potential problem with this gene model
DOFPDPNE_02046 3.7e-44
DOFPDPNE_02049 4.5e-152 glcU U sugar transport
DOFPDPNE_02050 2e-48
DOFPDPNE_02051 2.5e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
DOFPDPNE_02052 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DOFPDPNE_02053 1.3e-21
DOFPDPNE_02054 2.3e-65 arsC 1.20.4.1 P Belongs to the ArsC family
DOFPDPNE_02055 2.2e-178 I Carboxylesterase family
DOFPDPNE_02057 1.2e-214 M Glycosyl hydrolases family 25
DOFPDPNE_02058 0.0 S Predicted membrane protein (DUF2207)
DOFPDPNE_02059 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
DOFPDPNE_02060 2.5e-129 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
DOFPDPNE_02061 2.4e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
DOFPDPNE_02062 2.8e-257 S Uncharacterized protein conserved in bacteria (DUF2325)
DOFPDPNE_02063 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
DOFPDPNE_02064 2.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DOFPDPNE_02065 8.9e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DOFPDPNE_02066 3.7e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOFPDPNE_02067 1.6e-70 yqhY S Asp23 family, cell envelope-related function
DOFPDPNE_02068 6.2e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)