ORF_ID e_value Gene_name EC_number CAZy COGs Description
AFGLLKEO_00001 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AFGLLKEO_00002 7.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AFGLLKEO_00003 2.4e-33 yaaA S S4 domain
AFGLLKEO_00004 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AFGLLKEO_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
AFGLLKEO_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFGLLKEO_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFGLLKEO_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
AFGLLKEO_00011 1.8e-184 yaaC S YaaC-like Protein
AFGLLKEO_00012 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
AFGLLKEO_00013 1.2e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AFGLLKEO_00014 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AFGLLKEO_00015 2.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AFGLLKEO_00016 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AFGLLKEO_00017 5e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AFGLLKEO_00018 1.3e-09
AFGLLKEO_00019 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
AFGLLKEO_00020 1.1e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
AFGLLKEO_00021 8.9e-213 yaaH M Glycoside Hydrolase Family
AFGLLKEO_00022 2e-100 yaaI Q COG1335 Amidases related to nicotinamidase
AFGLLKEO_00023 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AFGLLKEO_00024 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFGLLKEO_00025 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AFGLLKEO_00026 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AFGLLKEO_00027 3.6e-32 yaaL S Protein of unknown function (DUF2508)
AFGLLKEO_00028 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
AFGLLKEO_00029 3.4e-39 S COG NOG14552 non supervised orthologous group
AFGLLKEO_00032 2.2e-30 csfB S Inhibitor of sigma-G Gin
AFGLLKEO_00033 1e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
AFGLLKEO_00034 1.1e-193 yaaN P Belongs to the TelA family
AFGLLKEO_00035 3.2e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
AFGLLKEO_00036 1.5e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AFGLLKEO_00037 7.5e-55 yaaQ S protein conserved in bacteria
AFGLLKEO_00038 5.3e-72 yaaR S protein conserved in bacteria
AFGLLKEO_00039 1.3e-182 holB 2.7.7.7 L DNA polymerase III
AFGLLKEO_00040 8.8e-145 yaaT S stage 0 sporulation protein
AFGLLKEO_00041 7.7e-37 yabA L Involved in initiation control of chromosome replication
AFGLLKEO_00042 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
AFGLLKEO_00043 4.7e-48 yazA L endonuclease containing a URI domain
AFGLLKEO_00044 1.4e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AFGLLKEO_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
AFGLLKEO_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFGLLKEO_00047 1.6e-145 tatD L hydrolase, TatD
AFGLLKEO_00048 1.8e-232 rpfB GH23 T protein conserved in bacteria
AFGLLKEO_00049 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AFGLLKEO_00050 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AFGLLKEO_00051 8.4e-146 yabG S peptidase
AFGLLKEO_00052 7.8e-39 veg S protein conserved in bacteria
AFGLLKEO_00053 2.9e-27 sspF S DNA topological change
AFGLLKEO_00054 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AFGLLKEO_00055 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
AFGLLKEO_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
AFGLLKEO_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
AFGLLKEO_00058 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AFGLLKEO_00059 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFGLLKEO_00060 2e-106 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AFGLLKEO_00061 2.5e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AFGLLKEO_00062 3.7e-40 yabK S Peptide ABC transporter permease
AFGLLKEO_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AFGLLKEO_00064 6.2e-91 spoVT K stage V sporulation protein
AFGLLKEO_00065 2.6e-286 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFGLLKEO_00066 8.3e-279 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
AFGLLKEO_00067 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
AFGLLKEO_00068 1.9e-49 yabP S Sporulation protein YabP
AFGLLKEO_00069 4.4e-104 yabQ S spore cortex biosynthesis protein
AFGLLKEO_00070 4.1e-57 divIC D Septum formation initiator
AFGLLKEO_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
AFGLLKEO_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
AFGLLKEO_00075 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
AFGLLKEO_00076 7.3e-186 KLT serine threonine protein kinase
AFGLLKEO_00077 2e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AFGLLKEO_00078 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AFGLLKEO_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFGLLKEO_00080 4.9e-139 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AFGLLKEO_00081 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AFGLLKEO_00082 3e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
AFGLLKEO_00083 1.5e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFGLLKEO_00084 4.2e-272 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AFGLLKEO_00085 1e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
AFGLLKEO_00086 3.1e-164 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
AFGLLKEO_00087 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AFGLLKEO_00088 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AFGLLKEO_00089 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AFGLLKEO_00090 4.5e-29 yazB K transcriptional
AFGLLKEO_00091 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFGLLKEO_00092 6.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AFGLLKEO_00093 3.4e-39 S COG NOG14552 non supervised orthologous group
AFGLLKEO_00095 1.3e-07
AFGLLKEO_00098 2e-08
AFGLLKEO_00103 3.4e-39 S COG NOG14552 non supervised orthologous group
AFGLLKEO_00104 7.5e-77 ctsR K Belongs to the CtsR family
AFGLLKEO_00105 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
AFGLLKEO_00106 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
AFGLLKEO_00107 0.0 clpC O Belongs to the ClpA ClpB family
AFGLLKEO_00108 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AFGLLKEO_00109 2.9e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AFGLLKEO_00110 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
AFGLLKEO_00111 1e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
AFGLLKEO_00112 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
AFGLLKEO_00113 2.8e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AFGLLKEO_00114 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
AFGLLKEO_00115 2.8e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFGLLKEO_00116 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AFGLLKEO_00117 2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFGLLKEO_00118 4.2e-89 yacP S RNA-binding protein containing a PIN domain
AFGLLKEO_00119 8.9e-116 sigH K Belongs to the sigma-70 factor family
AFGLLKEO_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AFGLLKEO_00121 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
AFGLLKEO_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AFGLLKEO_00123 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AFGLLKEO_00124 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AFGLLKEO_00125 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AFGLLKEO_00126 9.7e-109 rsmC 2.1.1.172 J Methyltransferase
AFGLLKEO_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFGLLKEO_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFGLLKEO_00129 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
AFGLLKEO_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AFGLLKEO_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AFGLLKEO_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AFGLLKEO_00133 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AFGLLKEO_00134 4.7e-190 ybaC 3.4.11.5 S Alpha/beta hydrolase family
AFGLLKEO_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
AFGLLKEO_00136 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AFGLLKEO_00137 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
AFGLLKEO_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AFGLLKEO_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFGLLKEO_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AFGLLKEO_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AFGLLKEO_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AFGLLKEO_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AFGLLKEO_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
AFGLLKEO_00145 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AFGLLKEO_00146 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AFGLLKEO_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AFGLLKEO_00148 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFGLLKEO_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFGLLKEO_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AFGLLKEO_00151 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AFGLLKEO_00152 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AFGLLKEO_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AFGLLKEO_00154 1.9e-23 rpmD J Ribosomal protein L30
AFGLLKEO_00155 1.1e-72 rplO J binds to the 23S rRNA
AFGLLKEO_00156 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AFGLLKEO_00157 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AFGLLKEO_00158 5.7e-143 map 3.4.11.18 E Methionine aminopeptidase
AFGLLKEO_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AFGLLKEO_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AFGLLKEO_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFGLLKEO_00162 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AFGLLKEO_00163 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFGLLKEO_00164 4.7e-58 rplQ J Ribosomal protein L17
AFGLLKEO_00165 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFGLLKEO_00166 1.3e-151 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFGLLKEO_00167 5.3e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFGLLKEO_00168 5.1e-144 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AFGLLKEO_00169 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AFGLLKEO_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
AFGLLKEO_00171 9.6e-146 ybaJ Q Methyltransferase domain
AFGLLKEO_00172 1.8e-86 yizA S Damage-inducible protein DinB
AFGLLKEO_00173 4.5e-79 ybaK S Protein of unknown function (DUF2521)
AFGLLKEO_00174 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
AFGLLKEO_00175 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
AFGLLKEO_00176 5.9e-76 gerD
AFGLLKEO_00177 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
AFGLLKEO_00178 8.4e-134 pdaB 3.5.1.104 G Polysaccharide deacetylase
AFGLLKEO_00179 3.4e-39 S COG NOG14552 non supervised orthologous group
AFGLLKEO_00182 1.6e-08
AFGLLKEO_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
AFGLLKEO_00186 2.2e-221 glcP G Major Facilitator Superfamily
AFGLLKEO_00187 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFGLLKEO_00188 3.9e-181 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
AFGLLKEO_00189 5.3e-203 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
AFGLLKEO_00190 2.5e-227 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
AFGLLKEO_00191 9.7e-175 ybaS 1.1.1.58 S Na -dependent transporter
AFGLLKEO_00192 8.3e-118 ybbA S Putative esterase
AFGLLKEO_00193 1.2e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFGLLKEO_00194 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFGLLKEO_00195 2e-172 feuA P Iron-uptake system-binding protein
AFGLLKEO_00196 0.0 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
AFGLLKEO_00197 4.9e-240 ybbC 3.2.1.52 S protein conserved in bacteria
AFGLLKEO_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
AFGLLKEO_00199 3.5e-249 yfeW 3.4.16.4 V Belongs to the UPF0214 family
AFGLLKEO_00200 1.8e-240 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFGLLKEO_00201 9.5e-164 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AFGLLKEO_00202 3.7e-87 ybbJ J acetyltransferase
AFGLLKEO_00203 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
AFGLLKEO_00209 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
AFGLLKEO_00210 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
AFGLLKEO_00211 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AFGLLKEO_00212 1.6e-226 ybbR S protein conserved in bacteria
AFGLLKEO_00213 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFGLLKEO_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AFGLLKEO_00215 2.5e-158 V ATPases associated with a variety of cellular activities
AFGLLKEO_00216 2.1e-109 S ABC-2 family transporter protein
AFGLLKEO_00217 3.7e-28 ybdN
AFGLLKEO_00219 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_00220 4.7e-188 T PhoQ Sensor
AFGLLKEO_00221 4.3e-138 V ABC transporter, ATP-binding protein
AFGLLKEO_00222 0.0 V ABC transporter (permease)
AFGLLKEO_00223 3e-12 cusA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AFGLLKEO_00224 3.9e-164 dkgB S Aldo/keto reductase family
AFGLLKEO_00225 1e-93 yxaC M effector of murein hydrolase
AFGLLKEO_00226 6.9e-52 S LrgA family
AFGLLKEO_00227 8e-73 yxaD K helix_turn_helix multiple antibiotic resistance protein
AFGLLKEO_00228 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
AFGLLKEO_00229 2.7e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AFGLLKEO_00230 5.1e-204 T COG4585 Signal transduction histidine kinase
AFGLLKEO_00231 2.9e-111 KT LuxR family transcriptional regulator
AFGLLKEO_00232 2.8e-171 V COG1131 ABC-type multidrug transport system, ATPase component
AFGLLKEO_00233 2.3e-210 V COG0842 ABC-type multidrug transport system, permease component
AFGLLKEO_00234 3e-204 V ABC-2 family transporter protein
AFGLLKEO_00235 5.8e-25
AFGLLKEO_00236 3.1e-78 S Domain of unknown function (DUF4879)
AFGLLKEO_00237 2e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
AFGLLKEO_00238 6.4e-112 yqeB
AFGLLKEO_00239 9.2e-40 ybyB
AFGLLKEO_00240 2.5e-292 ybeC E amino acid
AFGLLKEO_00242 1.9e-55
AFGLLKEO_00243 3.4e-15 S Protein of unknown function (DUF2651)
AFGLLKEO_00244 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AFGLLKEO_00245 1.7e-259 glpT G -transporter
AFGLLKEO_00246 1.3e-16 S Protein of unknown function (DUF2651)
AFGLLKEO_00247 5e-212 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
AFGLLKEO_00249 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
AFGLLKEO_00250 1.3e-30
AFGLLKEO_00251 1.2e-82 K Helix-turn-helix XRE-family like proteins
AFGLLKEO_00252 7e-203 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
AFGLLKEO_00253 6.2e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AFGLLKEO_00254 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFGLLKEO_00255 1.9e-86 ybfM S SNARE associated Golgi protein
AFGLLKEO_00256 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
AFGLLKEO_00257 6.5e-44 ybfN
AFGLLKEO_00258 2.7e-193 yceA S Belongs to the UPF0176 family
AFGLLKEO_00259 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFGLLKEO_00260 8.6e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
AFGLLKEO_00261 4.7e-258 mmuP E amino acid
AFGLLKEO_00262 1.1e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
AFGLLKEO_00263 5.4e-259 agcS E Sodium alanine symporter
AFGLLKEO_00264 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
AFGLLKEO_00265 1.4e-213 phoQ 2.7.13.3 T Histidine kinase
AFGLLKEO_00266 6.7e-173 glnL T Regulator
AFGLLKEO_00267 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
AFGLLKEO_00268 1.8e-156 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFGLLKEO_00269 1.5e-112 ydfN C nitroreductase
AFGLLKEO_00270 6.2e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
AFGLLKEO_00271 1.5e-62 mhqP S DoxX
AFGLLKEO_00272 2.8e-57 traF CO Thioredoxin
AFGLLKEO_00273 5.6e-62 ycbP S Protein of unknown function (DUF2512)
AFGLLKEO_00274 5.1e-80 sleB 3.5.1.28 M Cell wall
AFGLLKEO_00275 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
AFGLLKEO_00276 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
AFGLLKEO_00277 5.6e-127 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AFGLLKEO_00278 3.1e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AFGLLKEO_00279 6.7e-212 ycbU E Selenocysteine lyase
AFGLLKEO_00280 7.1e-243 lmrB EGP the major facilitator superfamily
AFGLLKEO_00281 5.3e-101 yxaF K Transcriptional regulator
AFGLLKEO_00282 4.7e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
AFGLLKEO_00283 8.7e-116 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
AFGLLKEO_00284 1.5e-197 yccF K DNA-templated transcriptional preinitiation complex assembly
AFGLLKEO_00285 4.6e-174 yccK C Aldo keto reductase
AFGLLKEO_00286 5.6e-178 ycdA S Domain of unknown function (DUF5105)
AFGLLKEO_00287 2.6e-274 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
AFGLLKEO_00288 7.9e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
AFGLLKEO_00289 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
AFGLLKEO_00290 4.2e-190 S response regulator aspartate phosphatase
AFGLLKEO_00291 5e-142 IQ Enoyl-(Acyl carrier protein) reductase
AFGLLKEO_00292 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
AFGLLKEO_00293 1.2e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
AFGLLKEO_00294 1.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
AFGLLKEO_00295 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
AFGLLKEO_00296 3.3e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFGLLKEO_00297 4.3e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
AFGLLKEO_00298 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
AFGLLKEO_00299 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
AFGLLKEO_00300 9.7e-138 terC P Protein of unknown function (DUF475)
AFGLLKEO_00301 0.0 yceG S Putative component of 'biosynthetic module'
AFGLLKEO_00302 2.3e-193 yceH P Belongs to the TelA family
AFGLLKEO_00303 3.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
AFGLLKEO_00304 3.9e-229 proV 3.6.3.32 E glycine betaine
AFGLLKEO_00305 1.6e-138 opuAB P glycine betaine
AFGLLKEO_00306 3.1e-164 opuAC E glycine betaine
AFGLLKEO_00307 2.1e-213 amhX S amidohydrolase
AFGLLKEO_00308 1.1e-230 ycgA S Membrane
AFGLLKEO_00309 2.2e-82 ycgB
AFGLLKEO_00310 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
AFGLLKEO_00311 5.7e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AFGLLKEO_00312 9.6e-262 mdr EGP Major facilitator Superfamily
AFGLLKEO_00313 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
AFGLLKEO_00314 4.7e-114 ycgF E Lysine exporter protein LysE YggA
AFGLLKEO_00315 1.6e-153 yqcI S YqcI/YcgG family
AFGLLKEO_00316 9.8e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
AFGLLKEO_00317 7.6e-114 ycgI S Domain of unknown function (DUF1989)
AFGLLKEO_00318 4.8e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AFGLLKEO_00320 4.3e-109 tmrB S AAA domain
AFGLLKEO_00321 2.7e-151 4.2.1.118 G Xylose isomerase-like TIM barrel
AFGLLKEO_00322 1.2e-233 G COG0477 Permeases of the major facilitator superfamily
AFGLLKEO_00323 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AFGLLKEO_00324 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
AFGLLKEO_00325 3.6e-148 ycgL S Predicted nucleotidyltransferase
AFGLLKEO_00326 2.3e-170 ycgM E Proline dehydrogenase
AFGLLKEO_00327 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
AFGLLKEO_00328 2.2e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFGLLKEO_00329 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
AFGLLKEO_00330 5.3e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
AFGLLKEO_00331 2.7e-282 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
AFGLLKEO_00332 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
AFGLLKEO_00333 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AFGLLKEO_00334 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFGLLKEO_00335 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
AFGLLKEO_00336 2.1e-224 nasA P COG2223 Nitrate nitrite transporter
AFGLLKEO_00337 1.3e-229 yciC S GTPases (G3E family)
AFGLLKEO_00338 1.4e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
AFGLLKEO_00339 5.6e-74 yckC S membrane
AFGLLKEO_00340 2.2e-51 S Protein of unknown function (DUF2680)
AFGLLKEO_00341 3.8e-297 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFGLLKEO_00342 2.9e-69 nin S Competence protein J (ComJ)
AFGLLKEO_00343 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
AFGLLKEO_00344 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
AFGLLKEO_00345 5.1e-108 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
AFGLLKEO_00346 2.8e-63 hxlR K transcriptional
AFGLLKEO_00347 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_00348 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_00349 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
AFGLLKEO_00350 1.5e-140 srfAD Q thioesterase
AFGLLKEO_00351 7.2e-250 bamJ E Aminotransferase class I and II
AFGLLKEO_00352 1.3e-64 S YcxB-like protein
AFGLLKEO_00354 3.2e-170 ycxC EG EamA-like transporter family
AFGLLKEO_00355 4.6e-249 ycxD K GntR family transcriptional regulator
AFGLLKEO_00356 1.6e-131 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
AFGLLKEO_00357 1.3e-111 yczE S membrane
AFGLLKEO_00358 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
AFGLLKEO_00359 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
AFGLLKEO_00360 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
AFGLLKEO_00361 3.9e-159 bsdA K LysR substrate binding domain
AFGLLKEO_00362 6.4e-102 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
AFGLLKEO_00363 6.3e-284 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
AFGLLKEO_00364 2e-38 bsdD 4.1.1.61 S response to toxic substance
AFGLLKEO_00365 5.2e-78 yclD
AFGLLKEO_00366 3.2e-270 dtpT E amino acid peptide transporter
AFGLLKEO_00367 2.7e-284 yclG M Pectate lyase superfamily protein
AFGLLKEO_00369 4.9e-296 gerKA EG Spore germination protein
AFGLLKEO_00370 1.6e-238 gerKC S spore germination
AFGLLKEO_00371 3.9e-196 gerKB F Spore germination protein
AFGLLKEO_00372 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFGLLKEO_00373 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFGLLKEO_00374 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
AFGLLKEO_00375 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
AFGLLKEO_00376 4.1e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
AFGLLKEO_00377 1.8e-220 yxeP 3.5.1.47 E hydrolase activity
AFGLLKEO_00378 2.8e-257 yxeQ S MmgE/PrpD family
AFGLLKEO_00379 2.4e-124 yclH P ABC transporter
AFGLLKEO_00380 7.9e-242 yclI V ABC transporter (permease) YclI
AFGLLKEO_00381 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_00382 2.8e-263 T PhoQ Sensor
AFGLLKEO_00383 4e-79 S aspartate phosphatase
AFGLLKEO_00386 2.6e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
AFGLLKEO_00387 2.3e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFGLLKEO_00388 3.6e-166 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFGLLKEO_00389 8.1e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
AFGLLKEO_00390 1.9e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
AFGLLKEO_00391 2.7e-250 ycnB EGP Major facilitator Superfamily
AFGLLKEO_00392 1.1e-153 ycnC K Transcriptional regulator
AFGLLKEO_00393 1.4e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
AFGLLKEO_00394 3.6e-45 ycnE S Monooxygenase
AFGLLKEO_00395 8.8e-53 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
AFGLLKEO_00396 2.8e-268 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFGLLKEO_00397 5.3e-221 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFGLLKEO_00398 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFGLLKEO_00399 3.6e-149 glcU U Glucose uptake
AFGLLKEO_00400 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFGLLKEO_00401 3.5e-98 ycnI S protein conserved in bacteria
AFGLLKEO_00402 1e-301 ycnJ P protein, homolog of Cu resistance protein CopC
AFGLLKEO_00403 5e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
AFGLLKEO_00404 1.6e-55
AFGLLKEO_00405 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
AFGLLKEO_00406 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
AFGLLKEO_00407 6.6e-212 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
AFGLLKEO_00408 3.2e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
AFGLLKEO_00410 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
AFGLLKEO_00411 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
AFGLLKEO_00412 4.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
AFGLLKEO_00413 1.1e-152 ycsI S Belongs to the D-glutamate cyclase family
AFGLLKEO_00414 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
AFGLLKEO_00415 9e-192 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
AFGLLKEO_00416 1.1e-131 kipR K Transcriptional regulator
AFGLLKEO_00417 8.4e-119 ycsK E anatomical structure formation involved in morphogenesis
AFGLLKEO_00419 5.1e-56 yczJ S biosynthesis
AFGLLKEO_00420 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
AFGLLKEO_00421 3.1e-175 ydhF S Oxidoreductase
AFGLLKEO_00422 0.0 mtlR K transcriptional regulator, MtlR
AFGLLKEO_00423 4.3e-291 ydaB IQ acyl-CoA ligase
AFGLLKEO_00424 9.7e-163 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFGLLKEO_00425 9.3e-97 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
AFGLLKEO_00426 1.4e-118 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AFGLLKEO_00427 1.4e-77 ydaG 1.4.3.5 S general stress protein
AFGLLKEO_00428 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
AFGLLKEO_00429 2.7e-48 ydzA EGP Major facilitator Superfamily
AFGLLKEO_00430 1.5e-74 lrpC K Transcriptional regulator
AFGLLKEO_00431 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFGLLKEO_00432 4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
AFGLLKEO_00433 2.7e-149 ydaK T Diguanylate cyclase, GGDEF domain
AFGLLKEO_00434 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
AFGLLKEO_00435 8.5e-232 ydaM M Glycosyl transferase family group 2
AFGLLKEO_00436 0.0 ydaN S Bacterial cellulose synthase subunit
AFGLLKEO_00437 0.0 ydaO E amino acid
AFGLLKEO_00438 2.2e-78 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
AFGLLKEO_00439 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AFGLLKEO_00440 2.2e-75 K acetyltransferase
AFGLLKEO_00442 7.4e-46
AFGLLKEO_00443 3.7e-210 S Histidine kinase
AFGLLKEO_00445 3.6e-11
AFGLLKEO_00447 5.1e-80
AFGLLKEO_00448 3.5e-100
AFGLLKEO_00449 7.2e-40
AFGLLKEO_00450 2.4e-226 mntH P H( )-stimulated, divalent metal cation uptake system
AFGLLKEO_00452 6.5e-34 ydaT
AFGLLKEO_00453 5.8e-73 yvaD S Family of unknown function (DUF5360)
AFGLLKEO_00454 4.1e-54 yvaE P Small Multidrug Resistance protein
AFGLLKEO_00455 1.8e-142 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
AFGLLKEO_00457 9.6e-64 ydbB G Cupin domain
AFGLLKEO_00458 6.3e-63 ydbC S Domain of unknown function (DUF4937
AFGLLKEO_00459 6.5e-156 ydbD P Catalase
AFGLLKEO_00460 2.2e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
AFGLLKEO_00461 5.9e-302 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
AFGLLKEO_00462 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
AFGLLKEO_00463 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFGLLKEO_00464 3.2e-160 ydbI S AI-2E family transporter
AFGLLKEO_00465 5e-173 ydbJ V ABC transporter, ATP-binding protein
AFGLLKEO_00466 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
AFGLLKEO_00467 2.1e-52 ydbL
AFGLLKEO_00468 1.2e-208 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
AFGLLKEO_00469 1.5e-10 S Fur-regulated basic protein B
AFGLLKEO_00470 5.8e-09 S Fur-regulated basic protein A
AFGLLKEO_00471 1.1e-60 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFGLLKEO_00472 5e-82 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFGLLKEO_00473 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AFGLLKEO_00474 3.2e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AFGLLKEO_00475 4.7e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AFGLLKEO_00476 1.3e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AFGLLKEO_00477 2.1e-82 ydbS S Bacterial PH domain
AFGLLKEO_00478 1.2e-266 ydbT S Membrane
AFGLLKEO_00479 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
AFGLLKEO_00480 5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AFGLLKEO_00481 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
AFGLLKEO_00482 1.3e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFGLLKEO_00483 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
AFGLLKEO_00484 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
AFGLLKEO_00485 6.1e-146 rsbR T Positive regulator of sigma-B
AFGLLKEO_00486 1.8e-57 rsbS T antagonist
AFGLLKEO_00487 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
AFGLLKEO_00488 4.6e-188 rsbU 3.1.3.3 KT phosphatase
AFGLLKEO_00489 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
AFGLLKEO_00490 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
AFGLLKEO_00491 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFGLLKEO_00492 2.3e-110 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
AFGLLKEO_00493 0.0 yhgF K COG2183 Transcriptional accessory protein
AFGLLKEO_00494 1.7e-14
AFGLLKEO_00495 1.3e-59 ydcK S Belongs to the SprT family
AFGLLKEO_00503 8.7e-98 ywrO 1.6.5.2 S Flavodoxin-like fold
AFGLLKEO_00504 3.1e-74 S SnoaL-like polyketide cyclase
AFGLLKEO_00505 4.4e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
AFGLLKEO_00506 2.4e-71 lrpA K transcriptional
AFGLLKEO_00507 2.6e-157 S Serine aminopeptidase, S33
AFGLLKEO_00508 7.4e-261 proP EGP Transporter
AFGLLKEO_00509 2.6e-49 ohrR K Transcriptional regulator
AFGLLKEO_00510 5.4e-86 S Domain of unknown function with cystatin-like fold (DUF4467)
AFGLLKEO_00511 1.4e-74 maoC I N-terminal half of MaoC dehydratase
AFGLLKEO_00512 3.8e-65 yyaQ S YjbR
AFGLLKEO_00513 5.1e-75 ywnA K Transcriptional regulator
AFGLLKEO_00514 5.3e-113 ywnB S NAD(P)H-binding
AFGLLKEO_00515 4.9e-102 K Bacterial regulatory proteins, tetR family
AFGLLKEO_00516 9.1e-133 C Enoyl-(Acyl carrier protein) reductase
AFGLLKEO_00517 6.8e-184 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
AFGLLKEO_00518 2.4e-178 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
AFGLLKEO_00519 6.9e-56 K Transcriptional regulator
AFGLLKEO_00520 1e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
AFGLLKEO_00521 1.4e-30 cspL K Cold shock
AFGLLKEO_00522 1.2e-79 carD K Transcription factor
AFGLLKEO_00523 9.2e-40 yrkD S protein conserved in bacteria
AFGLLKEO_00524 1.1e-83 yrkE O DsrE/DsrF/DrsH-like family
AFGLLKEO_00525 3.4e-64 P Rhodanese Homology Domain
AFGLLKEO_00526 1.8e-101 yrkF OP Belongs to the sulfur carrier protein TusA family
AFGLLKEO_00527 2.2e-199 yrkH P Rhodanese Homology Domain
AFGLLKEO_00528 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
AFGLLKEO_00529 3.5e-119 yrkJ S membrane transporter protein
AFGLLKEO_00530 2e-126 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
AFGLLKEO_00531 2.3e-107 S Protein of unknown function (DUF2812)
AFGLLKEO_00532 3.4e-52 K Transcriptional regulator PadR-like family
AFGLLKEO_00533 1.2e-174 ybfA 3.4.15.5 K FR47-like protein
AFGLLKEO_00534 1.8e-237 ybfB G COG0477 Permeases of the major facilitator superfamily
AFGLLKEO_00535 2.3e-184 S Patatin-like phospholipase
AFGLLKEO_00536 1.3e-84 S DinB superfamily
AFGLLKEO_00537 8.8e-65 G Cupin domain
AFGLLKEO_00540 1.6e-268 ygaK C COG0277 FAD FMN-containing dehydrogenases
AFGLLKEO_00541 1.5e-79 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFGLLKEO_00542 1.8e-170 czcD P COG1230 Co Zn Cd efflux system component
AFGLLKEO_00543 4.4e-202 trkA P Oxidoreductase
AFGLLKEO_00545 7e-103 yrkC G Cupin domain
AFGLLKEO_00547 2.6e-88 ykkA S Protein of unknown function (DUF664)
AFGLLKEO_00548 1.6e-150 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
AFGLLKEO_00550 2.4e-200 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
AFGLLKEO_00551 9.3e-57 ydeH
AFGLLKEO_00552 7.5e-85 F nucleoside 2-deoxyribosyltransferase
AFGLLKEO_00553 1.3e-195 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFGLLKEO_00554 1.2e-148 Q ubiE/COQ5 methyltransferase family
AFGLLKEO_00555 2.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AFGLLKEO_00556 1.4e-234 3.1.3.41 G Haloacid dehalogenase-like hydrolase
AFGLLKEO_00557 2.4e-170 S Sodium Bile acid symporter family
AFGLLKEO_00558 4e-203 adhA 1.1.1.1 C alcohol dehydrogenase
AFGLLKEO_00559 3.6e-67 yraB K helix_turn_helix, mercury resistance
AFGLLKEO_00560 3.1e-229 mleN_2 C antiporter
AFGLLKEO_00561 5.8e-266 K helix_turn_helix gluconate operon transcriptional repressor
AFGLLKEO_00562 8.4e-116 paiB K Transcriptional regulator
AFGLLKEO_00564 8.5e-113 ksgA1 I Ribosomal RNA adenine dimethylase
AFGLLKEO_00565 5.4e-124 T Transcriptional regulator
AFGLLKEO_00566 1.1e-192 T PhoQ Sensor
AFGLLKEO_00567 2.8e-106 S SNARE associated Golgi protein
AFGLLKEO_00568 2.7e-187 ydeR EGP Major facilitator Superfamily
AFGLLKEO_00569 4.5e-103 ydeS K Transcriptional regulator
AFGLLKEO_00570 3.3e-158 ydeK EG -transporter
AFGLLKEO_00571 3.9e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFGLLKEO_00572 1.9e-49 yraD M Spore coat protein
AFGLLKEO_00573 7.5e-26 yraE
AFGLLKEO_00574 2.2e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
AFGLLKEO_00575 9.9e-64 yraF M Spore coat protein
AFGLLKEO_00576 6.9e-37 yraG
AFGLLKEO_00577 1.8e-221 ydfH 2.7.13.3 T Histidine kinase
AFGLLKEO_00578 3.7e-111 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFGLLKEO_00579 0.0 ydfJ S drug exporters of the RND superfamily
AFGLLKEO_00580 9.1e-137 puuD S Peptidase C26
AFGLLKEO_00581 2.6e-302 expZ S ABC transporter
AFGLLKEO_00582 5.9e-102 ynaD J Acetyltransferase (GNAT) domain
AFGLLKEO_00583 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
AFGLLKEO_00584 1.6e-197 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
AFGLLKEO_00585 7.9e-211 tcaB EGP Major facilitator Superfamily
AFGLLKEO_00586 1.2e-227 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFGLLKEO_00587 2.7e-157 K Helix-turn-helix XRE-family like proteins
AFGLLKEO_00588 1.3e-123 ydhB S membrane transporter protein
AFGLLKEO_00589 2.4e-83 bltD 2.3.1.57 K FR47-like protein
AFGLLKEO_00590 5.7e-152 bltR K helix_turn_helix, mercury resistance
AFGLLKEO_00591 2.3e-151 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AFGLLKEO_00592 1.1e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
AFGLLKEO_00593 2.3e-147 ycgJ_1 Q ubiE/COQ5 methyltransferase family
AFGLLKEO_00594 3e-156 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
AFGLLKEO_00595 3.1e-21 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
AFGLLKEO_00596 1.3e-120 ydhC K FCD
AFGLLKEO_00597 1.7e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
AFGLLKEO_00600 1.6e-268 pbpE V Beta-lactamase
AFGLLKEO_00602 2.5e-98 ydhK M Protein of unknown function (DUF1541)
AFGLLKEO_00603 1.2e-195 pbuE EGP Major facilitator Superfamily
AFGLLKEO_00604 1.3e-133 ydhQ K UTRA
AFGLLKEO_00605 1.4e-119 K FCD
AFGLLKEO_00606 7.4e-217 yeaN P COG2807 Cyanate permease
AFGLLKEO_00607 2.6e-49 sugE P Small Multidrug Resistance protein
AFGLLKEO_00608 2.3e-51 ykkC P Small Multidrug Resistance protein
AFGLLKEO_00609 5.3e-104 yvdT K Transcriptional regulator
AFGLLKEO_00610 9.3e-297 yveA E amino acid
AFGLLKEO_00611 3.2e-166 ydhU P Catalase
AFGLLKEO_00612 6.4e-84 yndB S Activator of Hsp90 ATPase homolog 1-like protein
AFGLLKEO_00613 4.7e-185 yhfP 1.1.1.1 C Quinone oxidoreductase
AFGLLKEO_00614 1.2e-253 iolT EGP Major facilitator Superfamily
AFGLLKEO_00617 3.4e-39 S COG NOG14552 non supervised orthologous group
AFGLLKEO_00618 7.8e-08
AFGLLKEO_00620 1.4e-186 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AFGLLKEO_00621 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
AFGLLKEO_00622 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
AFGLLKEO_00623 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
AFGLLKEO_00624 2.7e-191 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AFGLLKEO_00625 0.0 ydiF S ABC transporter
AFGLLKEO_00626 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
AFGLLKEO_00627 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AFGLLKEO_00628 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
AFGLLKEO_00629 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AFGLLKEO_00630 1.7e-27 ydiK S Domain of unknown function (DUF4305)
AFGLLKEO_00631 2.5e-127 ydiL S CAAX protease self-immunity
AFGLLKEO_00632 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AFGLLKEO_00633 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AFGLLKEO_00634 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
AFGLLKEO_00637 4.2e-65
AFGLLKEO_00638 0.0 K NB-ARC domain
AFGLLKEO_00639 4.5e-202 gutB 1.1.1.14 E Dehydrogenase
AFGLLKEO_00640 2.3e-251 gutA G MFS/sugar transport protein
AFGLLKEO_00641 2.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
AFGLLKEO_00642 6.2e-30 yjdJ S Domain of unknown function (DUF4306)
AFGLLKEO_00643 2.7e-115 pspA KT Phage shock protein A
AFGLLKEO_00644 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFGLLKEO_00645 3.3e-122 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
AFGLLKEO_00646 1.9e-157 ydjI S virion core protein (lumpy skin disease virus)
AFGLLKEO_00647 0.0 yrhL I Acyltransferase family
AFGLLKEO_00648 1.2e-147 rsiV S Protein of unknown function (DUF3298)
AFGLLKEO_00649 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
AFGLLKEO_00650 1.8e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
AFGLLKEO_00651 1.4e-62 ydjM M Lytic transglycolase
AFGLLKEO_00652 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
AFGLLKEO_00654 7.2e-35 ydjO S Cold-inducible protein YdjO
AFGLLKEO_00655 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
AFGLLKEO_00656 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
AFGLLKEO_00657 5.8e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFGLLKEO_00658 3.5e-177 yeaC S COG0714 MoxR-like ATPases
AFGLLKEO_00659 1.6e-216 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
AFGLLKEO_00660 0.0 yebA E COG1305 Transglutaminase-like enzymes
AFGLLKEO_00661 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AFGLLKEO_00662 7.8e-94 sigV K Belongs to the sigma-70 factor family. ECF subfamily
AFGLLKEO_00663 8.6e-273 S Domain of unknown function (DUF4179)
AFGLLKEO_00664 6.2e-209 pbuG S permease
AFGLLKEO_00665 3e-134 yebC M Membrane
AFGLLKEO_00667 3.1e-93 yebE S UPF0316 protein
AFGLLKEO_00668 5.5e-29 yebG S NETI protein
AFGLLKEO_00669 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AFGLLKEO_00670 7.2e-225 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AFGLLKEO_00671 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AFGLLKEO_00672 2.2e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AFGLLKEO_00673 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFGLLKEO_00674 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFGLLKEO_00675 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFGLLKEO_00676 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AFGLLKEO_00677 4.2e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AFGLLKEO_00678 2.2e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AFGLLKEO_00679 4.1e-289 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AFGLLKEO_00680 6.1e-238 purD 6.3.4.13 F Belongs to the GARS family
AFGLLKEO_00681 1.2e-25 S Protein of unknown function (DUF2892)
AFGLLKEO_00682 0.0 yerA 3.5.4.2 F adenine deaminase
AFGLLKEO_00683 1.4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
AFGLLKEO_00684 2.4e-50 yerC S protein conserved in bacteria
AFGLLKEO_00685 7.9e-304 yerD 1.4.7.1 E Belongs to the glutamate synthase family
AFGLLKEO_00686 6.2e-128 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AFGLLKEO_00687 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AFGLLKEO_00688 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AFGLLKEO_00689 1.4e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
AFGLLKEO_00690 7.5e-199 yerI S homoserine kinase type II (protein kinase fold)
AFGLLKEO_00691 8.8e-122 sapB S MgtC SapB transporter
AFGLLKEO_00692 3.7e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFGLLKEO_00693 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFGLLKEO_00694 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AFGLLKEO_00695 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFGLLKEO_00696 9.6e-155 yerO K Transcriptional regulator
AFGLLKEO_00697 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AFGLLKEO_00698 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AFGLLKEO_00699 9.9e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFGLLKEO_00700 1.8e-300 hsdM 2.1.1.72 V Type I restriction-modification system
AFGLLKEO_00701 4e-234 3.1.21.3 V Type I restriction modification DNA specificity domain
AFGLLKEO_00702 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
AFGLLKEO_00704 3.5e-224 V Domain of unknown function (DUF3578)
AFGLLKEO_00705 2.6e-91 S Protein of unknown function, DUF600
AFGLLKEO_00706 4.5e-82 S Protein of unknown function, DUF600
AFGLLKEO_00707 2.9e-84 S Protein of unknown function, DUF600
AFGLLKEO_00708 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
AFGLLKEO_00709 9.4e-127 yeeN K transcriptional regulatory protein
AFGLLKEO_00711 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
AFGLLKEO_00712 3.3e-45 cotJB S CotJB protein
AFGLLKEO_00713 8.9e-104 cotJC P Spore Coat
AFGLLKEO_00714 1.6e-99 yesJ K Acetyltransferase (GNAT) family
AFGLLKEO_00716 8.7e-122 yetF S membrane
AFGLLKEO_00717 3.3e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
AFGLLKEO_00718 4e-65 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFGLLKEO_00719 1.8e-156 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFGLLKEO_00720 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
AFGLLKEO_00721 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
AFGLLKEO_00722 8.2e-106 yetJ S Belongs to the BI1 family
AFGLLKEO_00723 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
AFGLLKEO_00724 2.8e-210 yetM CH FAD binding domain
AFGLLKEO_00725 2.6e-197 yetN S Protein of unknown function (DUF3900)
AFGLLKEO_00726 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
AFGLLKEO_00728 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
AFGLLKEO_00729 6.7e-167 V ATPases associated with a variety of cellular activities
AFGLLKEO_00730 1.9e-127 V ABC-2 type transporter
AFGLLKEO_00731 6.4e-75 S protein homooligomerization
AFGLLKEO_00732 6.4e-128
AFGLLKEO_00733 1.6e-193 S ATP diphosphatase activity
AFGLLKEO_00734 1e-267 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
AFGLLKEO_00735 1e-153 sagB C Nitroreductase family
AFGLLKEO_00736 1e-114 S CAAX protease self-immunity
AFGLLKEO_00737 1.1e-147 2.1.1.163, 2.1.1.201 Q methyltransferase
AFGLLKEO_00739 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AFGLLKEO_00740 1.2e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
AFGLLKEO_00741 2.4e-172 yfnG 4.2.1.45 M dehydratase
AFGLLKEO_00742 1.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
AFGLLKEO_00743 2.1e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
AFGLLKEO_00744 2.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
AFGLLKEO_00745 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
AFGLLKEO_00746 4.2e-248 yfnA E amino acid
AFGLLKEO_00747 4.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFGLLKEO_00748 9.8e-115 yfmS NT chemotaxis protein
AFGLLKEO_00749 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
AFGLLKEO_00750 1.6e-210 M COG0463 Glycosyltransferases involved in cell wall biogenesis
AFGLLKEO_00751 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
AFGLLKEO_00752 6.2e-70 yfmP K transcriptional
AFGLLKEO_00753 2.1e-208 yfmO EGP Major facilitator Superfamily
AFGLLKEO_00754 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
AFGLLKEO_00755 7.7e-208 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
AFGLLKEO_00756 3.6e-19 yfmK 2.3.1.128 K acetyltransferase
AFGLLKEO_00757 6.3e-33 yfmK 2.3.1.128 K acetyltransferase
AFGLLKEO_00758 2e-191 yfmJ S N-terminal domain of oxidoreductase
AFGLLKEO_00759 1.7e-24 S Protein of unknown function (DUF3212)
AFGLLKEO_00760 1.3e-57 yflT S Heat induced stress protein YflT
AFGLLKEO_00761 8.2e-243 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
AFGLLKEO_00762 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
AFGLLKEO_00763 2.8e-35 Q PFAM Collagen triple helix
AFGLLKEO_00764 7.4e-98 Q PFAM Collagen triple helix
AFGLLKEO_00765 8.9e-141 Q calcium- and calmodulin-responsive adenylate cyclase activity
AFGLLKEO_00766 4.8e-87 M1-820 Q Collagen triple helix repeat (20 copies)
AFGLLKEO_00767 6.5e-277 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
AFGLLKEO_00768 9.5e-121 citT T response regulator
AFGLLKEO_00769 8.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
AFGLLKEO_00770 3.8e-227 citM C Citrate transporter
AFGLLKEO_00771 7.9e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
AFGLLKEO_00772 1.4e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AFGLLKEO_00773 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AFGLLKEO_00774 2.3e-124 yflK S protein conserved in bacteria
AFGLLKEO_00775 1.5e-14 yflJ S Protein of unknown function (DUF2639)
AFGLLKEO_00776 7e-19 yflI
AFGLLKEO_00777 3.1e-50 yflH S Protein of unknown function (DUF3243)
AFGLLKEO_00778 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
AFGLLKEO_00779 1.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
AFGLLKEO_00780 2.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
AFGLLKEO_00781 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AFGLLKEO_00782 7.8e-64 yhdN S Domain of unknown function (DUF1992)
AFGLLKEO_00783 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
AFGLLKEO_00784 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
AFGLLKEO_00785 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
AFGLLKEO_00786 6.6e-241 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFGLLKEO_00787 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AFGLLKEO_00788 9e-130 treR K transcriptional
AFGLLKEO_00789 1.2e-123 yfkO C nitroreductase
AFGLLKEO_00790 4.2e-125 yibF S YibE/F-like protein
AFGLLKEO_00791 5.2e-204 yibE S YibE/F-like protein
AFGLLKEO_00793 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
AFGLLKEO_00794 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
AFGLLKEO_00795 3e-187 K helix_turn _helix lactose operon repressor
AFGLLKEO_00796 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFGLLKEO_00797 7.3e-138 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AFGLLKEO_00798 1.3e-194 ydiM EGP Major facilitator Superfamily
AFGLLKEO_00799 7.1e-30 yfkK S Belongs to the UPF0435 family
AFGLLKEO_00800 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AFGLLKEO_00801 2e-52 yfkI S gas vesicle protein
AFGLLKEO_00802 6.8e-145 yihY S Belongs to the UPF0761 family
AFGLLKEO_00803 2.5e-07
AFGLLKEO_00804 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
AFGLLKEO_00805 1.3e-185 cax P COG0387 Ca2 H antiporter
AFGLLKEO_00806 1.9e-144 yfkD S YfkD-like protein
AFGLLKEO_00807 3.3e-147 yfkC M Mechanosensitive ion channel
AFGLLKEO_00808 2.7e-221 yfkA S YfkB-like domain
AFGLLKEO_00809 4.9e-27 yfjT
AFGLLKEO_00810 1.8e-155 pdaA G deacetylase
AFGLLKEO_00811 7.7e-152 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
AFGLLKEO_00812 5.4e-33
AFGLLKEO_00813 1.7e-184 corA P Mediates influx of magnesium ions
AFGLLKEO_00814 7.2e-166 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AFGLLKEO_00815 5.6e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFGLLKEO_00816 2.7e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFGLLKEO_00817 1.3e-95 yfjM S Psort location Cytoplasmic, score
AFGLLKEO_00818 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
AFGLLKEO_00819 5e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AFGLLKEO_00820 8.6e-218 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFGLLKEO_00821 1.5e-258 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
AFGLLKEO_00822 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
AFGLLKEO_00823 4.2e-15 sspH S Belongs to the SspH family
AFGLLKEO_00824 1.2e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
AFGLLKEO_00825 1e-139 glvR F Helix-turn-helix domain, rpiR family
AFGLLKEO_00826 1e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFGLLKEO_00827 0.0 yobO M COG5434 Endopolygalacturonase
AFGLLKEO_00828 0.0 yfiB3 V ABC transporter
AFGLLKEO_00829 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
AFGLLKEO_00830 2.4e-63 mhqP S DoxX
AFGLLKEO_00831 1.1e-161 yfiE 1.13.11.2 S glyoxalase
AFGLLKEO_00832 1.5e-172 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
AFGLLKEO_00833 1.7e-96 padR K transcriptional
AFGLLKEO_00834 6.5e-113 1.6.5.2 S NADPH-dependent FMN reductase
AFGLLKEO_00835 2.5e-184 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AFGLLKEO_00836 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
AFGLLKEO_00837 1.5e-45 yrdF K ribonuclease inhibitor
AFGLLKEO_00838 2.7e-102 yfiT S Belongs to the metal hydrolase YfiT family
AFGLLKEO_00839 6.4e-293 yfiU EGP Major facilitator Superfamily
AFGLLKEO_00840 5.6e-83 yfiV K transcriptional
AFGLLKEO_00841 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AFGLLKEO_00842 2.7e-168 yfhB 5.3.3.17 S PhzF family
AFGLLKEO_00843 3.3e-106 yfhC C nitroreductase
AFGLLKEO_00844 2.1e-25 yfhD S YfhD-like protein
AFGLLKEO_00846 3.3e-169 yfhF S nucleoside-diphosphate sugar epimerase
AFGLLKEO_00847 1.8e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
AFGLLKEO_00848 8.8e-53 yfhH S Protein of unknown function (DUF1811)
AFGLLKEO_00849 1.2e-206 yfhI EGP Major facilitator Superfamily
AFGLLKEO_00851 9.6e-169 mpr 3.4.21.19 M Belongs to the peptidase S1B family
AFGLLKEO_00852 4.4e-45 yfhJ S WVELL protein
AFGLLKEO_00853 1.8e-95 batE T Bacterial SH3 domain homologues
AFGLLKEO_00854 1.4e-35 yfhL S SdpI/YhfL protein family
AFGLLKEO_00855 1.5e-171 yfhM S Alpha/beta hydrolase family
AFGLLKEO_00856 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
AFGLLKEO_00857 0.0 yfhO S Bacterial membrane protein YfhO
AFGLLKEO_00858 2.1e-185 yfhP S membrane-bound metal-dependent
AFGLLKEO_00859 2.7e-210 mutY L A G-specific
AFGLLKEO_00860 8.2e-37 yfhS
AFGLLKEO_00861 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFGLLKEO_00863 1.5e-37 ygaB S YgaB-like protein
AFGLLKEO_00864 2.2e-104 ygaC J Belongs to the UPF0374 family
AFGLLKEO_00865 2.5e-306 ygaD V ABC transporter
AFGLLKEO_00866 1.1e-179 ygaE S Membrane
AFGLLKEO_00867 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
AFGLLKEO_00868 1.1e-86 bcp 1.11.1.15 O Peroxiredoxin
AFGLLKEO_00869 1.8e-80 perR P Belongs to the Fur family
AFGLLKEO_00870 1.5e-56 ygzB S UPF0295 protein
AFGLLKEO_00871 3.7e-165 ygxA S Nucleotidyltransferase-like
AFGLLKEO_00872 3.4e-39 S COG NOG14552 non supervised orthologous group
AFGLLKEO_00877 7.8e-08
AFGLLKEO_00885 1.6e-08
AFGLLKEO_00889 5.5e-289 C Na+/H+ antiporter family
AFGLLKEO_00890 1.2e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
AFGLLKEO_00891 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AFGLLKEO_00892 3e-267 ygaK C Berberine and berberine like
AFGLLKEO_00895 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
AFGLLKEO_00896 7.3e-188 S Amidohydrolase
AFGLLKEO_00897 1.4e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
AFGLLKEO_00898 4.8e-182 ssuA M Sulfonate ABC transporter
AFGLLKEO_00899 3.6e-146 ssuC P ABC transporter (permease)
AFGLLKEO_00900 1.4e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
AFGLLKEO_00901 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFGLLKEO_00902 3e-81 ygaO
AFGLLKEO_00903 4.8e-23 K Transcriptional regulator
AFGLLKEO_00905 1.6e-114 yhzB S B3/4 domain
AFGLLKEO_00906 8.4e-226 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AFGLLKEO_00907 4.8e-176 yhbB S Putative amidase domain
AFGLLKEO_00908 6.9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AFGLLKEO_00909 3.5e-109 yhbD K Protein of unknown function (DUF4004)
AFGLLKEO_00910 8.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
AFGLLKEO_00911 3.5e-65 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
AFGLLKEO_00913 0.0 prkA T Ser protein kinase
AFGLLKEO_00914 1.2e-216 yhbH S Belongs to the UPF0229 family
AFGLLKEO_00915 4.6e-74 yhbI K DNA-binding transcription factor activity
AFGLLKEO_00916 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
AFGLLKEO_00917 6.4e-285 yhcA EGP Major facilitator Superfamily
AFGLLKEO_00918 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
AFGLLKEO_00919 3.8e-55 yhcC
AFGLLKEO_00920 9.6e-53
AFGLLKEO_00921 2.5e-62 yhcF K Transcriptional regulator
AFGLLKEO_00922 1.6e-126 yhcG V ABC transporter, ATP-binding protein
AFGLLKEO_00923 4.1e-167 yhcH V ABC transporter, ATP-binding protein
AFGLLKEO_00924 5.1e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
AFGLLKEO_00925 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
AFGLLKEO_00926 3.5e-149 metQ M Belongs to the nlpA lipoprotein family
AFGLLKEO_00927 4.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
AFGLLKEO_00928 2.2e-222 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFGLLKEO_00929 4.8e-57 yhcM
AFGLLKEO_00930 3.9e-85 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFGLLKEO_00931 6e-163 yhcP
AFGLLKEO_00932 3.7e-117 yhcQ M Spore coat protein
AFGLLKEO_00933 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
AFGLLKEO_00934 1.6e-108 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
AFGLLKEO_00935 4.9e-173 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFGLLKEO_00936 1.3e-69 yhcU S Family of unknown function (DUF5365)
AFGLLKEO_00937 2.6e-68 yhcV S COG0517 FOG CBS domain
AFGLLKEO_00938 4.9e-125 yhcW 5.4.2.6 S hydrolase
AFGLLKEO_00939 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AFGLLKEO_00940 1.7e-262 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFGLLKEO_00941 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AFGLLKEO_00942 1.2e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
AFGLLKEO_00943 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFGLLKEO_00944 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AFGLLKEO_00945 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
AFGLLKEO_00946 1.8e-209 yhcY 2.7.13.3 T Histidine kinase
AFGLLKEO_00947 1.5e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFGLLKEO_00948 4.6e-91 azr 1.7.1.6 S NADPH-dependent FMN reductase
AFGLLKEO_00949 2.5e-39 yhdB S YhdB-like protein
AFGLLKEO_00950 1.1e-53 yhdC S Protein of unknown function (DUF3889)
AFGLLKEO_00951 1.6e-218 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
AFGLLKEO_00952 1.9e-74 nsrR K Transcriptional regulator
AFGLLKEO_00953 1.4e-257 ygxB M Conserved TM helix
AFGLLKEO_00954 1.2e-271 ycgB S Stage V sporulation protein R
AFGLLKEO_00955 6.2e-260 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
AFGLLKEO_00956 3.3e-128 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
AFGLLKEO_00957 9e-164 citR K Transcriptional regulator
AFGLLKEO_00958 1.3e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
AFGLLKEO_00959 5.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFGLLKEO_00960 4.1e-251 yhdG E amino acid
AFGLLKEO_00961 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
AFGLLKEO_00962 8.1e-45 yhdK S Sigma-M inhibitor protein
AFGLLKEO_00963 1.3e-201 yhdL S Sigma factor regulator N-terminal
AFGLLKEO_00964 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
AFGLLKEO_00965 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
AFGLLKEO_00966 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
AFGLLKEO_00967 4.3e-71 cueR K transcriptional
AFGLLKEO_00968 3.5e-227 yhdR 2.6.1.1 E Aminotransferase
AFGLLKEO_00969 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFGLLKEO_00970 2.9e-257 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
AFGLLKEO_00971 8.5e-52 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFGLLKEO_00972 1.7e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFGLLKEO_00973 2.8e-131 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AFGLLKEO_00975 1.6e-205 yhdY M Mechanosensitive ion channel
AFGLLKEO_00976 4.5e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
AFGLLKEO_00977 4.9e-159 yheN G deacetylase
AFGLLKEO_00978 4.3e-155 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
AFGLLKEO_00979 4.6e-88 pksA K Transcriptional regulator
AFGLLKEO_00980 1.2e-94 ymcC S Membrane
AFGLLKEO_00981 4.3e-86 T universal stress protein
AFGLLKEO_00983 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
AFGLLKEO_00984 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
AFGLLKEO_00985 1.1e-112 yheG GM NAD(P)H-binding
AFGLLKEO_00987 5.8e-29 sspB S spore protein
AFGLLKEO_00988 1.7e-36 yheE S Family of unknown function (DUF5342)
AFGLLKEO_00989 1.1e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
AFGLLKEO_00990 4.8e-215 yheC HJ YheC/D like ATP-grasp
AFGLLKEO_00991 5.9e-208 yheB S Belongs to the UPF0754 family
AFGLLKEO_00992 4e-54 yheA S Belongs to the UPF0342 family
AFGLLKEO_00993 1.2e-205 yhaZ L DNA alkylation repair enzyme
AFGLLKEO_00994 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
AFGLLKEO_00995 9.3e-294 hemZ H coproporphyrinogen III oxidase
AFGLLKEO_00996 1.8e-253 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
AFGLLKEO_00997 2.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
AFGLLKEO_00998 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
AFGLLKEO_01000 2.5e-138 yhaR 5.3.3.18 I enoyl-CoA hydratase
AFGLLKEO_01001 7.3e-15 S YhzD-like protein
AFGLLKEO_01002 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
AFGLLKEO_01003 1.9e-207 yhaP CP COG1668 ABC-type Na efflux pump, permease component
AFGLLKEO_01004 9.1e-239 yhaO L DNA repair exonuclease
AFGLLKEO_01005 0.0 yhaN L AAA domain
AFGLLKEO_01006 9e-178 yhaM L Shows a 3'-5' exoribonuclease activity
AFGLLKEO_01007 1.6e-32 yhaL S Sporulation protein YhaL
AFGLLKEO_01008 3.3e-123 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AFGLLKEO_01009 7e-95 yhaK S Putative zincin peptidase
AFGLLKEO_01010 9.9e-55 yhaI S Protein of unknown function (DUF1878)
AFGLLKEO_01011 8.6e-113 hpr K Negative regulator of protease production and sporulation
AFGLLKEO_01012 6.2e-39 yhaH S YtxH-like protein
AFGLLKEO_01013 2e-17
AFGLLKEO_01014 2.9e-77 trpP S Tryptophan transporter TrpP
AFGLLKEO_01015 1.3e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AFGLLKEO_01016 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
AFGLLKEO_01017 1.1e-135 ecsA V transporter (ATP-binding protein)
AFGLLKEO_01018 1.7e-221 ecsB U ABC transporter
AFGLLKEO_01019 3e-125 ecsC S EcsC protein family
AFGLLKEO_01020 2.2e-226 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
AFGLLKEO_01021 1.9e-245 yhfA C membrane
AFGLLKEO_01022 5.8e-91 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
AFGLLKEO_01023 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFGLLKEO_01024 3e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AFGLLKEO_01025 2.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
AFGLLKEO_01026 1.4e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AFGLLKEO_01027 3.2e-101 yhgD K Transcriptional regulator
AFGLLKEO_01028 6.5e-278 yhgE S YhgE Pip N-terminal domain protein
AFGLLKEO_01029 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFGLLKEO_01031 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
AFGLLKEO_01032 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFGLLKEO_01033 1.5e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
AFGLLKEO_01034 3.1e-189 lplJ 6.3.1.20 H Lipoate-protein ligase
AFGLLKEO_01035 8.2e-114 yhfK GM NmrA-like family
AFGLLKEO_01036 6.2e-301 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
AFGLLKEO_01037 8.7e-66 yhfM
AFGLLKEO_01038 6e-238 yhfN 3.4.24.84 O Peptidase M48
AFGLLKEO_01039 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
AFGLLKEO_01040 1.6e-160 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
AFGLLKEO_01041 3.6e-105 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
AFGLLKEO_01042 3.8e-204 vraB 2.3.1.9 I Belongs to the thiolase family
AFGLLKEO_01043 5.4e-283 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
AFGLLKEO_01044 9.3e-90 bioY S BioY family
AFGLLKEO_01045 1e-200 hemAT NT chemotaxis protein
AFGLLKEO_01046 3.9e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
AFGLLKEO_01047 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFGLLKEO_01048 1.3e-32 yhzC S IDEAL
AFGLLKEO_01049 1.9e-109 comK K Competence transcription factor
AFGLLKEO_01050 3.9e-68 frataxin S Domain of unknown function (DU1801)
AFGLLKEO_01051 3.9e-68 frataxin S Domain of unknown function (DU1801)
AFGLLKEO_01052 1.3e-93 mepB S MepB protein
AFGLLKEO_01053 1.9e-127 yrpD S Domain of unknown function, YrpD
AFGLLKEO_01054 1.6e-42 yhjA S Excalibur calcium-binding domain
AFGLLKEO_01055 3.9e-51 S Belongs to the UPF0145 family
AFGLLKEO_01056 1.3e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFGLLKEO_01057 1.4e-27 yhjC S Protein of unknown function (DUF3311)
AFGLLKEO_01058 1.7e-60 yhjD
AFGLLKEO_01059 4.8e-111 yhjE S SNARE associated Golgi protein
AFGLLKEO_01060 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
AFGLLKEO_01061 3e-281 yhjG CH FAD binding domain
AFGLLKEO_01062 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
AFGLLKEO_01063 5.1e-191 abrB S membrane
AFGLLKEO_01064 1.1e-209 blt EGP Major facilitator Superfamily
AFGLLKEO_01065 4.5e-109 K QacR-like protein, C-terminal region
AFGLLKEO_01066 2.6e-94 yhjR S Rubrerythrin
AFGLLKEO_01067 1.6e-126 ydfS S Protein of unknown function (DUF421)
AFGLLKEO_01068 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
AFGLLKEO_01069 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AFGLLKEO_01070 3e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AFGLLKEO_01071 0.0 sbcC L COG0419 ATPase involved in DNA repair
AFGLLKEO_01072 1.3e-50 yisB V COG1403 Restriction endonuclease
AFGLLKEO_01073 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
AFGLLKEO_01074 1.9e-65 gerPE S Spore germination protein GerPE
AFGLLKEO_01075 3.1e-23 gerPD S Spore germination protein
AFGLLKEO_01076 1.4e-62 gerPC S Spore germination protein
AFGLLKEO_01077 6.2e-35 gerPB S cell differentiation
AFGLLKEO_01078 8.4e-34 gerPA S Spore germination protein
AFGLLKEO_01079 5e-07 yisI S Spo0E like sporulation regulatory protein
AFGLLKEO_01080 1.3e-173 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
AFGLLKEO_01081 1.1e-59 yisL S UPF0344 protein
AFGLLKEO_01082 1.3e-99 yisN S Protein of unknown function (DUF2777)
AFGLLKEO_01083 0.0 asnO 6.3.5.4 E Asparagine synthase
AFGLLKEO_01084 6.7e-136 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
AFGLLKEO_01085 1.5e-245 yisQ V Mate efflux family protein
AFGLLKEO_01086 6.3e-162 yisR K Transcriptional regulator
AFGLLKEO_01087 1.3e-90 yisT S DinB family
AFGLLKEO_01088 1.2e-72 mcbG S Pentapeptide repeats (9 copies)
AFGLLKEO_01089 6.2e-81 yjcF S Acetyltransferase (GNAT) domain
AFGLLKEO_01090 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
AFGLLKEO_01091 6.6e-55 yajQ S Belongs to the UPF0234 family
AFGLLKEO_01092 1.8e-161 cvfB S protein conserved in bacteria
AFGLLKEO_01093 6.7e-176 yufN S ABC transporter substrate-binding protein PnrA-like
AFGLLKEO_01094 1.8e-237 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
AFGLLKEO_01095 1.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
AFGLLKEO_01097 1.3e-159 yitS S protein conserved in bacteria
AFGLLKEO_01098 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
AFGLLKEO_01099 2.9e-81 ipi S Intracellular proteinase inhibitor
AFGLLKEO_01100 4.4e-26 S Protein of unknown function (DUF3813)
AFGLLKEO_01101 3.5e-07
AFGLLKEO_01102 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
AFGLLKEO_01103 4.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
AFGLLKEO_01104 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
AFGLLKEO_01105 2.2e-81 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
AFGLLKEO_01106 7.8e-274 yitY C D-arabinono-1,4-lactone oxidase
AFGLLKEO_01107 4.1e-90 norB G Major Facilitator Superfamily
AFGLLKEO_01108 1e-198 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AFGLLKEO_01109 7.2e-228 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AFGLLKEO_01110 1.5e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
AFGLLKEO_01111 3.1e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
AFGLLKEO_01112 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AFGLLKEO_01113 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
AFGLLKEO_01114 4.2e-178 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AFGLLKEO_01115 1.2e-27 yjzC S YjzC-like protein
AFGLLKEO_01116 1.5e-23 yjzD S Protein of unknown function (DUF2929)
AFGLLKEO_01117 6.8e-141 yjaU I carboxylic ester hydrolase activity
AFGLLKEO_01118 1.5e-106 yjaV
AFGLLKEO_01119 1.9e-166 med S Transcriptional activator protein med
AFGLLKEO_01120 1.1e-26 comZ S ComZ
AFGLLKEO_01121 5.9e-32 yjzB
AFGLLKEO_01122 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFGLLKEO_01123 8.9e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFGLLKEO_01124 5.6e-149 yjaZ O Zn-dependent protease
AFGLLKEO_01125 3.3e-183 appD P Belongs to the ABC transporter superfamily
AFGLLKEO_01126 5.9e-188 appF E Belongs to the ABC transporter superfamily
AFGLLKEO_01127 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
AFGLLKEO_01128 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFGLLKEO_01129 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFGLLKEO_01130 5.5e-146 yjbA S Belongs to the UPF0736 family
AFGLLKEO_01131 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
AFGLLKEO_01132 0.0 oppA E ABC transporter substrate-binding protein
AFGLLKEO_01133 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFGLLKEO_01134 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFGLLKEO_01135 2.7e-202 oppD P Belongs to the ABC transporter superfamily
AFGLLKEO_01136 2.5e-172 oppF E Belongs to the ABC transporter superfamily
AFGLLKEO_01137 3.9e-234 S Putative glycosyl hydrolase domain
AFGLLKEO_01138 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFGLLKEO_01139 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AFGLLKEO_01140 1.9e-110 yjbE P Integral membrane protein TerC family
AFGLLKEO_01141 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
AFGLLKEO_01142 3.5e-224 yjbF S Competence protein
AFGLLKEO_01143 0.0 pepF E oligoendopeptidase F
AFGLLKEO_01144 5.8e-19
AFGLLKEO_01145 7.8e-171 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
AFGLLKEO_01146 4.8e-72 yjbI S Bacterial-like globin
AFGLLKEO_01147 1.2e-118 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
AFGLLKEO_01148 1.1e-101 yjbK S protein conserved in bacteria
AFGLLKEO_01149 1.6e-61 yjbL S Belongs to the UPF0738 family
AFGLLKEO_01150 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
AFGLLKEO_01151 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFGLLKEO_01152 5.7e-166 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFGLLKEO_01153 4.2e-146 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
AFGLLKEO_01154 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AFGLLKEO_01155 5.2e-138 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AFGLLKEO_01156 1.9e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
AFGLLKEO_01157 2.3e-220 thiO 1.4.3.19 E Glycine oxidase
AFGLLKEO_01158 1.4e-30 thiS H Thiamine biosynthesis
AFGLLKEO_01159 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
AFGLLKEO_01160 9.9e-191 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AFGLLKEO_01161 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AFGLLKEO_01162 1.4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
AFGLLKEO_01163 3e-89 yjbX S Spore coat protein
AFGLLKEO_01164 1e-83 cotZ S Spore coat protein
AFGLLKEO_01165 9.2e-94 cotY S Spore coat protein Z
AFGLLKEO_01166 1.5e-75 cotX S Spore Coat Protein X and V domain
AFGLLKEO_01167 1.1e-23 cotW
AFGLLKEO_01168 3.2e-57 cotV S Spore Coat Protein X and V domain
AFGLLKEO_01169 8.7e-57 yjcA S Protein of unknown function (DUF1360)
AFGLLKEO_01172 3.8e-38 spoVIF S Stage VI sporulation protein F
AFGLLKEO_01173 0.0 yjcD 3.6.4.12 L DNA helicase
AFGLLKEO_01174 1.2e-36
AFGLLKEO_01175 3.6e-145 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
AFGLLKEO_01176 2.3e-125 S ABC-2 type transporter
AFGLLKEO_01177 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
AFGLLKEO_01178 9.4e-36 K SpoVT / AbrB like domain
AFGLLKEO_01179 5e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFGLLKEO_01180 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
AFGLLKEO_01181 5.5e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
AFGLLKEO_01182 5.4e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AFGLLKEO_01183 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AFGLLKEO_01185 8.7e-31
AFGLLKEO_01186 2.8e-255 yobL S Bacterial EndoU nuclease
AFGLLKEO_01188 5.9e-87
AFGLLKEO_01190 3.9e-13
AFGLLKEO_01192 8.2e-57
AFGLLKEO_01193 0.0 yobL S Bacterial EndoU nuclease
AFGLLKEO_01194 3.2e-95
AFGLLKEO_01197 2.4e-135
AFGLLKEO_01200 5.7e-169 bla 3.5.2.6 V beta-lactamase
AFGLLKEO_01201 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
AFGLLKEO_01202 1.6e-255 yfjF EGP Belongs to the major facilitator superfamily
AFGLLKEO_01203 7.9e-82 napB K helix_turn_helix multiple antibiotic resistance protein
AFGLLKEO_01204 8.3e-223 ganA 3.2.1.89 G arabinogalactan
AFGLLKEO_01205 3.2e-294 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
AFGLLKEO_01206 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AFGLLKEO_01207 9e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AFGLLKEO_01208 0.0 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFGLLKEO_01209 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
AFGLLKEO_01210 7.3e-285 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
AFGLLKEO_01211 5.1e-139 lacR K COG1349 Transcriptional regulators of sugar metabolism
AFGLLKEO_01212 1.1e-127 5.4.2.6 S Haloacid dehalogenase-like hydrolase
AFGLLKEO_01213 1.5e-145 N Kelch motif
AFGLLKEO_01215 8.1e-106 yhiD S MgtC SapB transporter
AFGLLKEO_01217 7.5e-22 yjfB S Putative motility protein
AFGLLKEO_01218 2.6e-70 T PhoQ Sensor
AFGLLKEO_01219 1.7e-102 yjgB S Domain of unknown function (DUF4309)
AFGLLKEO_01220 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
AFGLLKEO_01221 4.3e-92 yjgD S Protein of unknown function (DUF1641)
AFGLLKEO_01222 4.2e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
AFGLLKEO_01223 3.6e-224 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
AFGLLKEO_01224 6.8e-29
AFGLLKEO_01225 5.9e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
AFGLLKEO_01226 9.3e-125 ybbM S transport system, permease component
AFGLLKEO_01227 2.4e-133 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
AFGLLKEO_01228 1.7e-179 yjlA EG Putative multidrug resistance efflux transporter
AFGLLKEO_01229 6.1e-93 yjlB S Cupin domain
AFGLLKEO_01230 7e-66 yjlC S Protein of unknown function (DUF1641)
AFGLLKEO_01231 3.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
AFGLLKEO_01232 5.4e-280 uxaC 5.3.1.12 G glucuronate isomerase
AFGLLKEO_01233 3e-254 yjmB G symporter YjmB
AFGLLKEO_01234 3.4e-183 exuR K transcriptional
AFGLLKEO_01235 1.5e-285 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
AFGLLKEO_01236 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
AFGLLKEO_01237 3.9e-131 MA20_18170 S membrane transporter protein
AFGLLKEO_01238 7.3e-80 yjoA S DinB family
AFGLLKEO_01239 4.9e-215 S response regulator aspartate phosphatase
AFGLLKEO_01241 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AFGLLKEO_01242 4.7e-61 yjqA S Bacterial PH domain
AFGLLKEO_01243 2.5e-112 yjqB S phage-related replication protein
AFGLLKEO_01244 7.8e-111 xkdA E IrrE N-terminal-like domain
AFGLLKEO_01245 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
AFGLLKEO_01247 1.4e-17 xkdB K sequence-specific DNA binding
AFGLLKEO_01248 2.6e-154 xkdC L Bacterial dnaA protein
AFGLLKEO_01251 2e-10 yqaO S Phage-like element PBSX protein XtrA
AFGLLKEO_01252 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
AFGLLKEO_01253 2.1e-35 xtmA
AFGLLKEO_01254 1.4e-41
AFGLLKEO_01256 1.7e-30 xkdX
AFGLLKEO_01257 7.6e-143 xepA
AFGLLKEO_01258 8.7e-38 xhlA S Haemolysin XhlA
AFGLLKEO_01259 1.3e-38 xhlB S SPP1 phage holin
AFGLLKEO_01260 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
AFGLLKEO_01261 8.7e-23 spoIISB S Stage II sporulation protein SB
AFGLLKEO_01262 7.5e-135 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
AFGLLKEO_01263 2e-175 pit P phosphate transporter
AFGLLKEO_01264 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
AFGLLKEO_01265 3.8e-243 steT E amino acid
AFGLLKEO_01266 5e-184 mhqA E COG0346 Lactoylglutathione lyase and related lyases
AFGLLKEO_01267 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AFGLLKEO_01268 3.4e-180 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
AFGLLKEO_01270 2.7e-207 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFGLLKEO_01271 3.2e-289 yubD P Major Facilitator Superfamily
AFGLLKEO_01273 6.5e-156 dppA E D-aminopeptidase
AFGLLKEO_01274 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFGLLKEO_01275 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFGLLKEO_01276 5.4e-192 dppD P Belongs to the ABC transporter superfamily
AFGLLKEO_01277 0.0 dppE E ABC transporter substrate-binding protein
AFGLLKEO_01278 6.8e-178 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
AFGLLKEO_01279 1e-204 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
AFGLLKEO_01280 6.8e-175 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
AFGLLKEO_01281 1.5e-183 ykfD E Belongs to the ABC transporter superfamily
AFGLLKEO_01282 1.3e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
AFGLLKEO_01283 1.2e-160 ykgA E Amidinotransferase
AFGLLKEO_01284 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
AFGLLKEO_01285 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AFGLLKEO_01286 9.4e-53 ykkC P Multidrug resistance protein
AFGLLKEO_01287 3.4e-49 ykkD P Multidrug resistance protein
AFGLLKEO_01288 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
AFGLLKEO_01289 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AFGLLKEO_01290 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AFGLLKEO_01291 1.5e-71 ohrA O Organic hydroperoxide resistance protein
AFGLLKEO_01292 6.1e-88 ohrR K COG1846 Transcriptional regulators
AFGLLKEO_01293 4.2e-71 ohrB O Organic hydroperoxide resistance protein
AFGLLKEO_01294 9.5e-61 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AFGLLKEO_01296 8.1e-218 M Glycosyl transferase family 2
AFGLLKEO_01297 2.2e-135 M PFAM Collagen triple helix repeat (20 copies)
AFGLLKEO_01298 6.5e-218 hcaT 1.5.1.2 EGP Major facilitator Superfamily
AFGLLKEO_01299 4.1e-124 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
AFGLLKEO_01300 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AFGLLKEO_01301 1.2e-177 isp O Belongs to the peptidase S8 family
AFGLLKEO_01302 8.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFGLLKEO_01303 9.3e-133 ykoC P Cobalt transport protein
AFGLLKEO_01304 0.0 P ABC transporter, ATP-binding protein
AFGLLKEO_01305 2.4e-99 ykoE S ABC-type cobalt transport system, permease component
AFGLLKEO_01306 1.2e-246 ydhD M Glycosyl hydrolase
AFGLLKEO_01308 2.2e-238 mgtE P Acts as a magnesium transporter
AFGLLKEO_01309 5.4e-53 tnrA K transcriptional
AFGLLKEO_01310 1.9e-16
AFGLLKEO_01311 3.1e-26 ykoL
AFGLLKEO_01312 1.1e-80 ykoM K transcriptional
AFGLLKEO_01313 2.2e-99 ykoP G polysaccharide deacetylase
AFGLLKEO_01314 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
AFGLLKEO_01315 1.4e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AFGLLKEO_01316 4.1e-101 ykoX S membrane-associated protein
AFGLLKEO_01317 9.2e-136 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
AFGLLKEO_01318 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFGLLKEO_01319 8.1e-120 rsgI S Anti-sigma factor N-terminus
AFGLLKEO_01320 2.5e-26 sspD S small acid-soluble spore protein
AFGLLKEO_01321 2.7e-126 ykrK S Domain of unknown function (DUF1836)
AFGLLKEO_01322 4.1e-156 htpX O Belongs to the peptidase M48B family
AFGLLKEO_01323 4.3e-242 ktrB P COG0168 Trk-type K transport systems, membrane components
AFGLLKEO_01324 4.7e-116 ydfR S Protein of unknown function (DUF421)
AFGLLKEO_01325 7.9e-24 ykzE
AFGLLKEO_01326 8.2e-193 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
AFGLLKEO_01327 0.0 kinE 2.7.13.3 T Histidine kinase
AFGLLKEO_01328 2.4e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AFGLLKEO_01330 4.4e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AFGLLKEO_01331 1.2e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AFGLLKEO_01332 1.2e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AFGLLKEO_01333 5.8e-230 mtnE 2.6.1.83 E Aminotransferase
AFGLLKEO_01334 2.5e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
AFGLLKEO_01335 4.4e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AFGLLKEO_01336 2.2e-116 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
AFGLLKEO_01337 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AFGLLKEO_01338 3.4e-10 S Spo0E like sporulation regulatory protein
AFGLLKEO_01339 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
AFGLLKEO_01340 1.5e-77 ykvE K transcriptional
AFGLLKEO_01341 2.7e-127 motB N Flagellar motor protein
AFGLLKEO_01342 1.1e-136 motA N flagellar motor
AFGLLKEO_01343 0.0 clpE O Belongs to the ClpA ClpB family
AFGLLKEO_01344 1.4e-184 ykvI S membrane
AFGLLKEO_01345 1.8e-193
AFGLLKEO_01346 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AFGLLKEO_01347 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
AFGLLKEO_01348 2.2e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
AFGLLKEO_01349 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AFGLLKEO_01351 1.5e-58 ykvN K Transcriptional regulator
AFGLLKEO_01352 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
AFGLLKEO_01353 1.4e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AFGLLKEO_01354 7e-46 ykvR S Protein of unknown function (DUF3219)
AFGLLKEO_01355 7.8e-25 ykvS S protein conserved in bacteria
AFGLLKEO_01356 6e-28
AFGLLKEO_01357 6.3e-111 ykvT 3.5.1.28 M Cell Wall Hydrolase
AFGLLKEO_01358 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFGLLKEO_01359 1.1e-89 stoA CO thiol-disulfide
AFGLLKEO_01360 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
AFGLLKEO_01361 7.4e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
AFGLLKEO_01363 1.2e-177 ykvZ 5.1.1.1 K Transcriptional regulator
AFGLLKEO_01364 5.1e-156 glcT K antiterminator
AFGLLKEO_01365 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFGLLKEO_01366 2.1e-39 ptsH G phosphocarrier protein HPr
AFGLLKEO_01367 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AFGLLKEO_01368 6.1e-38 splA S Transcriptional regulator
AFGLLKEO_01369 2.9e-190 splB 4.1.99.14 L Spore photoproduct lyase
AFGLLKEO_01370 4.4e-267 mcpC NT chemotaxis protein
AFGLLKEO_01371 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
AFGLLKEO_01372 7.2e-65
AFGLLKEO_01373 1.4e-120 ykwD J protein with SCP PR1 domains
AFGLLKEO_01374 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
AFGLLKEO_01375 2.6e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
AFGLLKEO_01376 1.3e-215 patA 2.6.1.1 E Aminotransferase
AFGLLKEO_01377 2.3e-09
AFGLLKEO_01378 3.7e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
AFGLLKEO_01379 1.4e-83 ykyB S YkyB-like protein
AFGLLKEO_01380 1.6e-241 ykuC EGP Major facilitator Superfamily
AFGLLKEO_01381 3.2e-89 ykuD S protein conserved in bacteria
AFGLLKEO_01382 3.8e-159 ykuE S Metallophosphoesterase
AFGLLKEO_01383 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFGLLKEO_01384 1.5e-233 ykuI T Diguanylate phosphodiesterase
AFGLLKEO_01385 3.9e-37 ykuJ S protein conserved in bacteria
AFGLLKEO_01386 7.6e-94 ykuK S Ribonuclease H-like
AFGLLKEO_01387 2.5e-26 ykzF S Antirepressor AbbA
AFGLLKEO_01388 1e-75 ykuL S CBS domain
AFGLLKEO_01389 4.6e-168 ccpC K Transcriptional regulator
AFGLLKEO_01390 6.1e-90 fld C Flavodoxin
AFGLLKEO_01391 4.4e-174 ykuO
AFGLLKEO_01392 1.1e-80 fld C Flavodoxin
AFGLLKEO_01393 8.8e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AFGLLKEO_01394 5.3e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AFGLLKEO_01395 4.8e-38 ykuS S Belongs to the UPF0180 family
AFGLLKEO_01396 1.5e-141 ykuT M Mechanosensitive ion channel
AFGLLKEO_01397 7.7e-82 ykuV CO thiol-disulfide
AFGLLKEO_01398 1.5e-98 rok K Repressor of ComK
AFGLLKEO_01399 8.6e-163 yknT
AFGLLKEO_01400 3e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
AFGLLKEO_01401 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AFGLLKEO_01402 9.6e-247 moeA 2.10.1.1 H molybdopterin
AFGLLKEO_01403 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
AFGLLKEO_01404 7.1e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
AFGLLKEO_01405 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AFGLLKEO_01406 6.6e-109 yknW S Yip1 domain
AFGLLKEO_01407 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFGLLKEO_01408 6.1e-123 macB V ABC transporter, ATP-binding protein
AFGLLKEO_01409 4.9e-213 yknZ V ABC transporter (permease)
AFGLLKEO_01410 1.1e-133 fruR K Transcriptional regulator
AFGLLKEO_01411 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
AFGLLKEO_01412 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
AFGLLKEO_01413 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
AFGLLKEO_01414 8.9e-38 ykoA
AFGLLKEO_01415 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
AFGLLKEO_01416 1.1e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFGLLKEO_01417 4.5e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
AFGLLKEO_01418 7.2e-12 S Uncharacterized protein YkpC
AFGLLKEO_01419 6.9e-184 mreB D Rod-share determining protein MreBH
AFGLLKEO_01420 2.1e-45 abrB K of stationary sporulation gene expression
AFGLLKEO_01421 3.7e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
AFGLLKEO_01422 2.8e-151 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
AFGLLKEO_01423 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
AFGLLKEO_01424 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AFGLLKEO_01425 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFGLLKEO_01426 8.2e-31 ykzG S Belongs to the UPF0356 family
AFGLLKEO_01427 1.6e-148 ykrA S hydrolases of the HAD superfamily
AFGLLKEO_01428 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AFGLLKEO_01430 8.1e-106 recN L Putative cell-wall binding lipoprotein
AFGLLKEO_01431 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AFGLLKEO_01432 0.0 Q Polyketide synthase of type I
AFGLLKEO_01433 0.0 Q polyketide synthase
AFGLLKEO_01434 0.0 Q Polyketide synthase of type I
AFGLLKEO_01435 0.0 Q Polyketide synthase of type I
AFGLLKEO_01436 0.0 Q Polyketide synthase of type I
AFGLLKEO_01437 0.0 Q Polyketide synthase of type I
AFGLLKEO_01438 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
AFGLLKEO_01439 1.2e-213 V Beta-lactamase
AFGLLKEO_01440 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
AFGLLKEO_01441 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AFGLLKEO_01442 3.4e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFGLLKEO_01443 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
AFGLLKEO_01444 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
AFGLLKEO_01445 4.4e-141 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
AFGLLKEO_01446 3.1e-278 speA 4.1.1.19 E Arginine
AFGLLKEO_01447 1.6e-42 yktA S Belongs to the UPF0223 family
AFGLLKEO_01448 4.9e-119 yktB S Belongs to the UPF0637 family
AFGLLKEO_01449 9.7e-25 ykzI
AFGLLKEO_01450 4.2e-152 suhB 3.1.3.25 G Inositol monophosphatase
AFGLLKEO_01451 1.8e-83 ykzC S Acetyltransferase (GNAT) family
AFGLLKEO_01452 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
AFGLLKEO_01453 4.3e-200 ylaA
AFGLLKEO_01454 5e-142
AFGLLKEO_01455 8.9e-46 ylaB
AFGLLKEO_01456 2.2e-93 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
AFGLLKEO_01457 9.8e-14 sigC S Putative zinc-finger
AFGLLKEO_01458 4.4e-40 ylaE
AFGLLKEO_01459 6.7e-24 S Family of unknown function (DUF5325)
AFGLLKEO_01460 0.0 typA T GTP-binding protein TypA
AFGLLKEO_01461 1.3e-48 ylaH S YlaH-like protein
AFGLLKEO_01462 1e-33 ylaI S protein conserved in bacteria
AFGLLKEO_01463 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFGLLKEO_01464 5.8e-247 phoH T ATPase related to phosphate starvation-inducible protein PhoH
AFGLLKEO_01465 7.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AFGLLKEO_01466 1.8e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
AFGLLKEO_01467 8.7e-44 ylaN S Belongs to the UPF0358 family
AFGLLKEO_01468 9e-215 ftsW D Belongs to the SEDS family
AFGLLKEO_01469 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AFGLLKEO_01470 2e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
AFGLLKEO_01471 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
AFGLLKEO_01472 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
AFGLLKEO_01473 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AFGLLKEO_01474 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
AFGLLKEO_01475 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
AFGLLKEO_01476 1.1e-166 ctaG S cytochrome c oxidase
AFGLLKEO_01477 5.9e-61 ylbA S YugN-like family
AFGLLKEO_01478 2.2e-73 ylbB T COG0517 FOG CBS domain
AFGLLKEO_01479 2.1e-199 ylbC S protein with SCP PR1 domains
AFGLLKEO_01480 4.5e-57 ylbD S Putative coat protein
AFGLLKEO_01481 8.8e-37 ylbE S YlbE-like protein
AFGLLKEO_01482 1.2e-71 ylbF S Belongs to the UPF0342 family
AFGLLKEO_01483 5.5e-43 ylbG S UPF0298 protein
AFGLLKEO_01485 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
AFGLLKEO_01486 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AFGLLKEO_01487 2e-217 ylbJ S Sporulation integral membrane protein YlbJ
AFGLLKEO_01488 8.9e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
AFGLLKEO_01489 5.5e-189 ylbL T Belongs to the peptidase S16 family
AFGLLKEO_01490 1.4e-231 ylbM S Belongs to the UPF0348 family
AFGLLKEO_01491 2.7e-91 yceD S metal-binding, possibly nucleic acid-binding protein
AFGLLKEO_01492 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AFGLLKEO_01493 1.2e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
AFGLLKEO_01494 8.1e-90 ylbP K n-acetyltransferase
AFGLLKEO_01495 3.5e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFGLLKEO_01496 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AFGLLKEO_01497 8.9e-78 mraZ K Belongs to the MraZ family
AFGLLKEO_01498 5.1e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AFGLLKEO_01499 2.9e-52 ftsL D Essential cell division protein
AFGLLKEO_01500 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
AFGLLKEO_01501 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
AFGLLKEO_01502 1.4e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AFGLLKEO_01503 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AFGLLKEO_01504 1.2e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AFGLLKEO_01505 2.2e-185 spoVE D Belongs to the SEDS family
AFGLLKEO_01506 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AFGLLKEO_01507 5.6e-169 murB 1.3.1.98 M cell wall formation
AFGLLKEO_01508 1.3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AFGLLKEO_01509 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AFGLLKEO_01510 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFGLLKEO_01512 0.0 bpr O COG1404 Subtilisin-like serine proteases
AFGLLKEO_01513 4e-162 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
AFGLLKEO_01514 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFGLLKEO_01515 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFGLLKEO_01516 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
AFGLLKEO_01517 2.7e-257 argE 3.5.1.16 E Acetylornithine deacetylase
AFGLLKEO_01518 2.2e-38 ylmC S sporulation protein
AFGLLKEO_01519 1e-161 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
AFGLLKEO_01520 2.5e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AFGLLKEO_01521 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AFGLLKEO_01522 5.2e-41 yggT S membrane
AFGLLKEO_01523 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
AFGLLKEO_01524 8.9e-68 divIVA D Cell division initiation protein
AFGLLKEO_01525 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AFGLLKEO_01526 6.2e-66 dksA T COG1734 DnaK suppressor protein
AFGLLKEO_01527 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AFGLLKEO_01528 4.6e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFGLLKEO_01529 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AFGLLKEO_01530 3.6e-233 pyrP F Xanthine uracil
AFGLLKEO_01531 1.5e-169 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AFGLLKEO_01532 4.9e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AFGLLKEO_01533 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AFGLLKEO_01534 0.0 carB 6.3.5.5 F Belongs to the CarB family
AFGLLKEO_01535 8.2e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
AFGLLKEO_01536 1.9e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AFGLLKEO_01537 4.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AFGLLKEO_01538 3.8e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AFGLLKEO_01540 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
AFGLLKEO_01541 1.8e-179 cysP P phosphate transporter
AFGLLKEO_01542 2.7e-224 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
AFGLLKEO_01543 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
AFGLLKEO_01544 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
AFGLLKEO_01545 3.4e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
AFGLLKEO_01546 1.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
AFGLLKEO_01547 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
AFGLLKEO_01548 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
AFGLLKEO_01549 7.7e-155 yloC S stress-induced protein
AFGLLKEO_01550 1.5e-40 ylzA S Belongs to the UPF0296 family
AFGLLKEO_01551 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AFGLLKEO_01552 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AFGLLKEO_01553 2.3e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AFGLLKEO_01554 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFGLLKEO_01555 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AFGLLKEO_01556 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AFGLLKEO_01557 4.2e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AFGLLKEO_01558 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AFGLLKEO_01559 9.3e-141 stp 3.1.3.16 T phosphatase
AFGLLKEO_01560 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
AFGLLKEO_01561 5.7e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AFGLLKEO_01562 9.4e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AFGLLKEO_01563 1.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
AFGLLKEO_01564 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AFGLLKEO_01565 5.5e-59 asp S protein conserved in bacteria
AFGLLKEO_01566 3.4e-305 yloV S kinase related to dihydroxyacetone kinase
AFGLLKEO_01567 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
AFGLLKEO_01568 7.1e-156 sdaAA 4.3.1.17 E L-serine dehydratase
AFGLLKEO_01569 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AFGLLKEO_01570 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
AFGLLKEO_01571 1.2e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AFGLLKEO_01572 4.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AFGLLKEO_01573 4.6e-129 IQ reductase
AFGLLKEO_01574 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFGLLKEO_01575 1.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AFGLLKEO_01576 0.0 smc D Required for chromosome condensation and partitioning
AFGLLKEO_01577 4.4e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AFGLLKEO_01578 9.1e-144 S Phosphotransferase enzyme family
AFGLLKEO_01579 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AFGLLKEO_01580 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AFGLLKEO_01581 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AFGLLKEO_01582 1.7e-35 ylqC S Belongs to the UPF0109 family
AFGLLKEO_01583 1.3e-61 ylqD S YlqD protein
AFGLLKEO_01584 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AFGLLKEO_01585 2.9e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AFGLLKEO_01586 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AFGLLKEO_01587 6.4e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AFGLLKEO_01588 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFGLLKEO_01589 0.0 ylqG
AFGLLKEO_01590 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
AFGLLKEO_01591 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
AFGLLKEO_01592 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AFGLLKEO_01593 1.9e-172 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
AFGLLKEO_01594 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFGLLKEO_01595 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AFGLLKEO_01596 7.2e-172 xerC L tyrosine recombinase XerC
AFGLLKEO_01597 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AFGLLKEO_01598 1.6e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AFGLLKEO_01599 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AFGLLKEO_01600 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
AFGLLKEO_01601 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
AFGLLKEO_01602 2.5e-31 fliE N Flagellar hook-basal body
AFGLLKEO_01603 1.4e-263 fliF N The M ring may be actively involved in energy transduction
AFGLLKEO_01604 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
AFGLLKEO_01605 1.3e-91 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
AFGLLKEO_01606 5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
AFGLLKEO_01607 4.5e-71 fliJ N Flagellar biosynthesis chaperone
AFGLLKEO_01608 4.4e-48 ylxF S MgtE intracellular N domain
AFGLLKEO_01609 1.8e-208 fliK N Flagellar hook-length control protein
AFGLLKEO_01610 4.8e-73 flgD N Flagellar basal body rod modification protein
AFGLLKEO_01611 4e-139 flgG N Flagellar basal body rod
AFGLLKEO_01612 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
AFGLLKEO_01613 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
AFGLLKEO_01614 1.9e-190 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AFGLLKEO_01615 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
AFGLLKEO_01616 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
AFGLLKEO_01617 4.3e-110 fliP N Plays a role in the flagellum-specific transport system
AFGLLKEO_01618 2e-37 fliQ N Role in flagellar biosynthesis
AFGLLKEO_01619 4e-131 fliR N Flagellar biosynthetic protein FliR
AFGLLKEO_01620 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AFGLLKEO_01621 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AFGLLKEO_01622 1.9e-195 flhF N Flagellar biosynthesis regulator FlhF
AFGLLKEO_01623 7.5e-158 flhG D Belongs to the ParA family
AFGLLKEO_01624 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
AFGLLKEO_01625 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
AFGLLKEO_01626 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
AFGLLKEO_01627 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
AFGLLKEO_01628 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
AFGLLKEO_01629 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFGLLKEO_01630 8.1e-55 ylxL
AFGLLKEO_01631 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
AFGLLKEO_01632 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AFGLLKEO_01633 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AFGLLKEO_01634 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AFGLLKEO_01635 2.2e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AFGLLKEO_01636 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
AFGLLKEO_01637 2e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
AFGLLKEO_01638 3.1e-234 rasP M zinc metalloprotease
AFGLLKEO_01639 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AFGLLKEO_01640 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFGLLKEO_01641 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
AFGLLKEO_01642 5.4e-206 nusA K Participates in both transcription termination and antitermination
AFGLLKEO_01643 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
AFGLLKEO_01644 1.8e-47 ylxQ J ribosomal protein
AFGLLKEO_01645 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AFGLLKEO_01646 3.9e-44 ylxP S protein conserved in bacteria
AFGLLKEO_01647 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AFGLLKEO_01648 8.6e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AFGLLKEO_01649 9.3e-183 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AFGLLKEO_01650 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AFGLLKEO_01651 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
AFGLLKEO_01652 8e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
AFGLLKEO_01653 3.6e-235 pepR S Belongs to the peptidase M16 family
AFGLLKEO_01654 2.6e-42 ymxH S YlmC YmxH family
AFGLLKEO_01655 1.1e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
AFGLLKEO_01656 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
AFGLLKEO_01657 2.6e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AFGLLKEO_01658 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
AFGLLKEO_01659 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFGLLKEO_01660 5.2e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFGLLKEO_01661 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
AFGLLKEO_01662 6.3e-31 S YlzJ-like protein
AFGLLKEO_01663 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
AFGLLKEO_01664 1.8e-133 ymfC K Transcriptional regulator
AFGLLKEO_01665 1.7e-230 ymfD EGP Major facilitator Superfamily
AFGLLKEO_01666 1.3e-76 K helix_turn_helix multiple antibiotic resistance protein
AFGLLKEO_01667 0.0 ydgH S drug exporters of the RND superfamily
AFGLLKEO_01668 1.2e-238 ymfF S Peptidase M16
AFGLLKEO_01669 2.3e-245 ymfH S zinc protease
AFGLLKEO_01670 1.6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
AFGLLKEO_01671 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
AFGLLKEO_01672 3.5e-143 ymfK S Protein of unknown function (DUF3388)
AFGLLKEO_01673 4.8e-128 ymfM S protein conserved in bacteria
AFGLLKEO_01674 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFGLLKEO_01675 1.7e-232 cinA 3.5.1.42 S Belongs to the CinA family
AFGLLKEO_01676 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AFGLLKEO_01677 1.3e-194 pbpX V Beta-lactamase
AFGLLKEO_01678 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
AFGLLKEO_01679 4.9e-153 ymdB S protein conserved in bacteria
AFGLLKEO_01680 1.2e-36 spoVS S Stage V sporulation protein S
AFGLLKEO_01681 1.6e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
AFGLLKEO_01682 6.1e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
AFGLLKEO_01683 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AFGLLKEO_01684 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
AFGLLKEO_01685 1.7e-88 cotE S Spore coat protein
AFGLLKEO_01686 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AFGLLKEO_01687 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AFGLLKEO_01689 3.9e-130 pksB 3.1.2.6 S Polyketide biosynthesis
AFGLLKEO_01690 6.8e-164 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AFGLLKEO_01691 3.9e-184 pksD Q Acyl transferase domain
AFGLLKEO_01692 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AFGLLKEO_01693 1.3e-35 acpK IQ Phosphopantetheine attachment site
AFGLLKEO_01694 1.3e-245 pksG 2.3.3.10 I synthase
AFGLLKEO_01695 4.8e-145 pksH 4.2.1.18 I enoyl-CoA hydratase
AFGLLKEO_01696 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
AFGLLKEO_01697 0.0 rhiB IQ polyketide synthase
AFGLLKEO_01698 0.0 Q Polyketide synthase of type I
AFGLLKEO_01699 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
AFGLLKEO_01700 0.0 dhbF IQ polyketide synthase
AFGLLKEO_01701 0.0 pks13 HQ Beta-ketoacyl synthase
AFGLLKEO_01702 2.8e-232 cypA C Cytochrome P450
AFGLLKEO_01703 7.5e-79 nucB M Deoxyribonuclease NucA/NucB
AFGLLKEO_01704 9.4e-119 yoaK S Membrane
AFGLLKEO_01705 1.4e-62 ymzB
AFGLLKEO_01706 4.7e-257 aprX O Belongs to the peptidase S8 family
AFGLLKEO_01708 1.4e-127 ymaC S Replication protein
AFGLLKEO_01709 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
AFGLLKEO_01710 5.2e-54 ebrB P Small Multidrug Resistance protein
AFGLLKEO_01711 3.1e-48 ebrA P Small Multidrug Resistance protein
AFGLLKEO_01713 1.4e-47 ymaF S YmaF family
AFGLLKEO_01714 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AFGLLKEO_01715 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
AFGLLKEO_01716 2.2e-44
AFGLLKEO_01717 1.8e-20 ymzA
AFGLLKEO_01718 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
AFGLLKEO_01719 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFGLLKEO_01720 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFGLLKEO_01721 2.4e-110 ymaB S MutT family
AFGLLKEO_01722 1.9e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
AFGLLKEO_01723 1.3e-176 spoVK O stage V sporulation protein K
AFGLLKEO_01724 2.2e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AFGLLKEO_01725 5.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
AFGLLKEO_01726 4.3e-68 glnR K transcriptional
AFGLLKEO_01727 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
AFGLLKEO_01728 1e-08 L Belongs to the 'phage' integrase family
AFGLLKEO_01729 2.6e-15
AFGLLKEO_01730 2.9e-95
AFGLLKEO_01732 7.4e-216 mrjp G Major royal jelly protein
AFGLLKEO_01733 6.7e-254 xynT G MFS/sugar transport protein
AFGLLKEO_01734 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
AFGLLKEO_01735 8.3e-218 xylR GK ROK family
AFGLLKEO_01736 2.6e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
AFGLLKEO_01737 2.1e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
AFGLLKEO_01738 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
AFGLLKEO_01743 5.4e-17
AFGLLKEO_01744 4e-56 dinB S DinB family
AFGLLKEO_01745 3.5e-188 adhP 1.1.1.1 C alcohol dehydrogenase
AFGLLKEO_01747 2.1e-148 yoaP 3.1.3.18 K YoaP-like
AFGLLKEO_01748 1.3e-101 J Acetyltransferase (GNAT) domain
AFGLLKEO_01749 4.3e-69
AFGLLKEO_01751 1.7e-121 ynaE S Domain of unknown function (DUF3885)
AFGLLKEO_01752 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFGLLKEO_01753 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
AFGLLKEO_01755 2.4e-95 yvgO
AFGLLKEO_01757 0.0 yobO M Pectate lyase superfamily protein
AFGLLKEO_01758 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
AFGLLKEO_01759 1.4e-150 yndL S Replication protein
AFGLLKEO_01760 1.6e-07
AFGLLKEO_01761 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
AFGLLKEO_01762 1.1e-72 yndM S Protein of unknown function (DUF2512)
AFGLLKEO_01763 2.1e-12 yoaW
AFGLLKEO_01764 2.4e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AFGLLKEO_01765 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
AFGLLKEO_01766 3.5e-112 yneB L resolvase
AFGLLKEO_01767 9.8e-33 ynzC S UPF0291 protein
AFGLLKEO_01768 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AFGLLKEO_01769 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
AFGLLKEO_01770 2.3e-28 yneF S UPF0154 protein
AFGLLKEO_01771 2.1e-23 ynzD S Spo0E like sporulation regulatory protein
AFGLLKEO_01772 1.3e-125 ccdA O cytochrome c biogenesis protein
AFGLLKEO_01773 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
AFGLLKEO_01774 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
AFGLLKEO_01775 8.5e-75 yneK S Protein of unknown function (DUF2621)
AFGLLKEO_01776 1e-63 hspX O Spore coat protein
AFGLLKEO_01777 2.3e-19 sspP S Belongs to the SspP family
AFGLLKEO_01778 7.5e-15 sspO S Belongs to the SspO family
AFGLLKEO_01779 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AFGLLKEO_01780 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AFGLLKEO_01782 2.7e-33 tlp S Belongs to the Tlp family
AFGLLKEO_01783 1.3e-75 yneP S Thioesterase-like superfamily
AFGLLKEO_01784 4.4e-54 yneQ
AFGLLKEO_01785 1.3e-50 yneR S Belongs to the HesB IscA family
AFGLLKEO_01786 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AFGLLKEO_01787 1.5e-68 yccU S CoA-binding protein
AFGLLKEO_01788 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFGLLKEO_01789 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFGLLKEO_01790 1.2e-13
AFGLLKEO_01791 5.1e-41 ynfC
AFGLLKEO_01792 2.2e-252 agcS E Sodium alanine symporter
AFGLLKEO_01793 5e-184 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
AFGLLKEO_01794 7.2e-197 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
AFGLLKEO_01795 3.1e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
AFGLLKEO_01796 9.5e-216 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
AFGLLKEO_01797 9.8e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFGLLKEO_01798 4.4e-183 kdgR_1 K transcriptional
AFGLLKEO_01799 5.4e-226 exuT G Sugar (and other) transporter
AFGLLKEO_01800 4.3e-160 yndG S DoxX-like family
AFGLLKEO_01801 3.4e-41 yndH S Domain of unknown function (DUF4166)
AFGLLKEO_01802 2.3e-311 yndJ S YndJ-like protein
AFGLLKEO_01804 1.4e-220 S Platelet-activating factor acetylhydrolase, isoform II
AFGLLKEO_01805 1.9e-299 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
AFGLLKEO_01806 5.6e-52 S Domain of unknown function (DUF4870)
AFGLLKEO_01807 6.7e-238 T PhoQ Sensor
AFGLLKEO_01808 5.2e-130 T Transcriptional regulatory protein, C terminal
AFGLLKEO_01809 1.8e-253 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
AFGLLKEO_01810 4.7e-301 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
AFGLLKEO_01811 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_01812 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_01813 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_01814 2.7e-227 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AFGLLKEO_01815 8.1e-140 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
AFGLLKEO_01816 1.9e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
AFGLLKEO_01817 3.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AFGLLKEO_01818 1.3e-257 yxjC EG COG2610 H gluconate symporter and related permeases
AFGLLKEO_01819 7.8e-227 bioI 1.14.14.46 C Cytochrome P450
AFGLLKEO_01820 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AFGLLKEO_01821 1.4e-130 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AFGLLKEO_01822 1.7e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
AFGLLKEO_01823 1.9e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
AFGLLKEO_01824 5.5e-149 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
AFGLLKEO_01825 1.7e-72 yngA S membrane
AFGLLKEO_01826 1.4e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AFGLLKEO_01827 3.2e-104 yngC S SNARE associated Golgi protein
AFGLLKEO_01828 2.6e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
AFGLLKEO_01829 8e-140 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
AFGLLKEO_01830 5e-170 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
AFGLLKEO_01831 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
AFGLLKEO_01832 4.9e-254 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
AFGLLKEO_01833 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
AFGLLKEO_01834 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
AFGLLKEO_01835 3.2e-310 yngK T Glycosyl hydrolase-like 10
AFGLLKEO_01836 4.1e-65 yngL S Protein of unknown function (DUF1360)
AFGLLKEO_01837 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
AFGLLKEO_01838 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_01839 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_01840 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_01841 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_01842 1.6e-274 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
AFGLLKEO_01843 1.1e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
AFGLLKEO_01844 2.7e-247 yoeA V MATE efflux family protein
AFGLLKEO_01845 1.8e-98 yoeB S IseA DL-endopeptidase inhibitor
AFGLLKEO_01847 3.5e-97 L Integrase
AFGLLKEO_01848 1.8e-34 yoeD G Helix-turn-helix domain
AFGLLKEO_01849 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
AFGLLKEO_01850 1.1e-201 ybcL EGP Major facilitator Superfamily
AFGLLKEO_01851 1.8e-50 ybzH K Helix-turn-helix domain
AFGLLKEO_01853 2.3e-159 gltR1 K Transcriptional regulator
AFGLLKEO_01854 5.3e-189 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
AFGLLKEO_01855 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
AFGLLKEO_01856 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
AFGLLKEO_01857 3.3e-153 gltC K Transcriptional regulator
AFGLLKEO_01858 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AFGLLKEO_01859 2e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFGLLKEO_01860 1e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
AFGLLKEO_01861 1.1e-77 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
AFGLLKEO_01862 6.3e-45 L Transposase
AFGLLKEO_01863 2e-138 IQ Enoyl-(Acyl carrier protein) reductase
AFGLLKEO_01864 6e-227 K helix_turn_helix, arabinose operon control protein
AFGLLKEO_01865 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AFGLLKEO_01866 2.1e-43 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AFGLLKEO_01867 6.4e-142 yoxB
AFGLLKEO_01868 2.2e-203 yoaB EGP Major facilitator Superfamily
AFGLLKEO_01869 1.1e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
AFGLLKEO_01870 3.9e-195 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFGLLKEO_01871 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFGLLKEO_01872 6.2e-16 yoaF
AFGLLKEO_01874 7.1e-101 hpr K helix_turn_helix multiple antibiotic resistance protein
AFGLLKEO_01875 1.6e-45
AFGLLKEO_01876 2.5e-88 S SMI1-KNR4 cell-wall
AFGLLKEO_01877 0.0 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
AFGLLKEO_01878 4.9e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
AFGLLKEO_01879 7.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
AFGLLKEO_01880 7.5e-95 yobS K Transcriptional regulator
AFGLLKEO_01881 4.5e-137 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
AFGLLKEO_01882 1.9e-92 yobW
AFGLLKEO_01883 3.4e-55 czrA K transcriptional
AFGLLKEO_01884 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
AFGLLKEO_01885 2.8e-91 yozB S membrane
AFGLLKEO_01886 5.4e-144 yocB J Protein required for attachment to host cells
AFGLLKEO_01887 1.9e-94 yocC
AFGLLKEO_01888 5.3e-189 yocD 3.4.17.13 V peptidase S66
AFGLLKEO_01890 2.5e-118 yocH CBM50 M COG1388 FOG LysM repeat
AFGLLKEO_01891 0.0 recQ 3.6.4.12 L DNA helicase
AFGLLKEO_01892 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AFGLLKEO_01894 3e-60 dksA T general stress protein
AFGLLKEO_01895 7.8e-10 yocL
AFGLLKEO_01896 1.7e-08
AFGLLKEO_01897 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
AFGLLKEO_01898 3.8e-44 yozN
AFGLLKEO_01899 8.5e-37 yocN
AFGLLKEO_01900 2.4e-56 yozO S Bacterial PH domain
AFGLLKEO_01902 1.6e-31 yozC
AFGLLKEO_01903 1.5e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
AFGLLKEO_01904 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
AFGLLKEO_01905 3.8e-167 sodA 1.15.1.1 P Superoxide dismutase
AFGLLKEO_01906 3e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
AFGLLKEO_01907 5.8e-164 yocS S -transporter
AFGLLKEO_01908 5.1e-144 S Metallo-beta-lactamase superfamily
AFGLLKEO_01909 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
AFGLLKEO_01910 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
AFGLLKEO_01911 0.0 yojO P Von Willebrand factor
AFGLLKEO_01912 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
AFGLLKEO_01913 2e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AFGLLKEO_01914 1e-229 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
AFGLLKEO_01915 3e-226 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
AFGLLKEO_01916 7.4e-112 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AFGLLKEO_01918 5.9e-247 norM V Multidrug efflux pump
AFGLLKEO_01919 4.5e-152 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFGLLKEO_01920 2.5e-126 yojG S deacetylase
AFGLLKEO_01921 9.7e-61 yojF S Protein of unknown function (DUF1806)
AFGLLKEO_01922 4.9e-23
AFGLLKEO_01923 9.2e-164 rarD S -transporter
AFGLLKEO_01924 1.3e-81 yozR S COG0071 Molecular chaperone (small heat shock protein)
AFGLLKEO_01926 1.6e-67 yodA S tautomerase
AFGLLKEO_01927 1.4e-70 yoaQ S Evidence 4 Homologs of previously reported genes of
AFGLLKEO_01928 1.4e-56 yodB K transcriptional
AFGLLKEO_01929 1.2e-106 yodC C nitroreductase
AFGLLKEO_01930 2.7e-111 mhqD S Carboxylesterase
AFGLLKEO_01931 9.7e-177 yodE E COG0346 Lactoylglutathione lyase and related lyases
AFGLLKEO_01932 1.4e-19 S Protein of unknown function (DUF3311)
AFGLLKEO_01933 3.5e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFGLLKEO_01934 7.4e-288 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
AFGLLKEO_01935 1.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFGLLKEO_01936 5.2e-133 yydK K Transcriptional regulator
AFGLLKEO_01937 4.2e-256 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
AFGLLKEO_01938 8.9e-130 yodH Q Methyltransferase
AFGLLKEO_01939 1.1e-34 yodI
AFGLLKEO_01940 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
AFGLLKEO_01941 9.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
AFGLLKEO_01943 8.6e-56 yodL S YodL-like
AFGLLKEO_01944 5e-105 yodM 3.6.1.27 I Acid phosphatase homologues
AFGLLKEO_01945 6.2e-24 yozD S YozD-like protein
AFGLLKEO_01947 1.7e-125 yodN
AFGLLKEO_01948 4.1e-36 yozE S Belongs to the UPF0346 family
AFGLLKEO_01949 8.3e-47 yokU S YokU-like protein, putative antitoxin
AFGLLKEO_01950 3.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
AFGLLKEO_01951 1.4e-161 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
AFGLLKEO_01952 1.8e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
AFGLLKEO_01953 1.2e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
AFGLLKEO_01954 5.8e-126 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AFGLLKEO_01955 2.1e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFGLLKEO_01957 4e-147 yiiD K acetyltransferase
AFGLLKEO_01958 4.4e-252 cgeD M maturation of the outermost layer of the spore
AFGLLKEO_01959 1e-42 cgeC
AFGLLKEO_01960 9.8e-55 cgeA
AFGLLKEO_01961 1.5e-183 cgeB S Spore maturation protein
AFGLLKEO_01962 6.6e-223 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
AFGLLKEO_01963 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
AFGLLKEO_01967 1.4e-212 S aspartate phosphatase
AFGLLKEO_01968 7.1e-89 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFGLLKEO_01969 1.7e-276 baeB 3.1.2.6, 3.4.21.102 P Rhodanese Homology Domain
AFGLLKEO_01970 8.3e-229 fccB 1.8.5.4 S Pyridine nucleotide-disulphide oxidoreductase
AFGLLKEO_01971 1.5e-98 nreC T helix_turn_helix, Lux Regulon
AFGLLKEO_01972 4.7e-199 2.7.13.3 T Histidine kinase
AFGLLKEO_01973 1.8e-84 yrkJ S response to heat
AFGLLKEO_01975 5.6e-103 yokK S SMI1 / KNR4 family
AFGLLKEO_01976 2.5e-129 S A nuclease of the HNH/ENDO VII superfamily with conserved WHH
AFGLLKEO_01977 0.0 yokA L Recombinase
AFGLLKEO_01978 1.4e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
AFGLLKEO_01979 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
AFGLLKEO_01980 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AFGLLKEO_01981 4.7e-67 ypoP K transcriptional
AFGLLKEO_01982 5.5e-98 ypmS S protein conserved in bacteria
AFGLLKEO_01983 4e-136 ypmR E GDSL-like Lipase/Acylhydrolase
AFGLLKEO_01984 1e-116 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
AFGLLKEO_01985 2.6e-39 ypmP S Protein of unknown function (DUF2535)
AFGLLKEO_01986 2.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AFGLLKEO_01987 4.1e-181 pspF K Transcriptional regulator
AFGLLKEO_01988 9.3e-110 hlyIII S protein, Hemolysin III
AFGLLKEO_01989 5e-116 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
AFGLLKEO_01990 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AFGLLKEO_01991 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFGLLKEO_01992 2.7e-114 ypjP S YpjP-like protein
AFGLLKEO_01993 2.7e-132 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
AFGLLKEO_01994 1e-75 yphP S Belongs to the UPF0403 family
AFGLLKEO_01995 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AFGLLKEO_01996 6.6e-159 ypgR C COG0694 Thioredoxin-like proteins and domains
AFGLLKEO_01997 1.5e-101 ypgQ S phosphohydrolase
AFGLLKEO_01998 1.1e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
AFGLLKEO_01999 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AFGLLKEO_02000 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
AFGLLKEO_02001 1e-30 cspD K Cold-shock protein
AFGLLKEO_02002 3.3e-12 degR
AFGLLKEO_02003 7.2e-37 S Protein of unknown function (DUF2564)
AFGLLKEO_02004 1.5e-28 ypeQ S Zinc-finger
AFGLLKEO_02005 6.3e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
AFGLLKEO_02006 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AFGLLKEO_02007 4.9e-69 rnhA 3.1.26.4 L Ribonuclease
AFGLLKEO_02009 4.8e-165 polA 2.7.7.7 L 5'3' exonuclease
AFGLLKEO_02011 3.5e-39 ypbS S Protein of unknown function (DUF2533)
AFGLLKEO_02012 0.0 ypbR S Dynamin family
AFGLLKEO_02013 1.1e-89 ypbQ S protein conserved in bacteria
AFGLLKEO_02014 2.8e-207 bcsA Q Naringenin-chalcone synthase
AFGLLKEO_02015 1e-110 J Acetyltransferase (GNAT) domain
AFGLLKEO_02016 6.2e-51 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
AFGLLKEO_02017 1.5e-08 S Bacillus cereus group antimicrobial protein
AFGLLKEO_02018 5.2e-99 ydfR S Protein of unknown function (DUF421)
AFGLLKEO_02019 4.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
AFGLLKEO_02021 1.3e-235 pbuX F xanthine
AFGLLKEO_02022 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AFGLLKEO_02023 3.8e-295 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AFGLLKEO_02024 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
AFGLLKEO_02026 6.6e-22 S YpzG-like protein
AFGLLKEO_02027 3.8e-78 yqgA
AFGLLKEO_02028 4.2e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AFGLLKEO_02029 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AFGLLKEO_02030 1.7e-99 ypsA S Belongs to the UPF0398 family
AFGLLKEO_02031 9.9e-33 cotD S Inner spore coat protein D
AFGLLKEO_02033 7.8e-238 yprB L RNase_H superfamily
AFGLLKEO_02034 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
AFGLLKEO_02035 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
AFGLLKEO_02036 7.7e-73 hspX O Belongs to the small heat shock protein (HSP20) family
AFGLLKEO_02037 1e-51 yppG S YppG-like protein
AFGLLKEO_02039 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
AFGLLKEO_02042 2.6e-188 yppC S Protein of unknown function (DUF2515)
AFGLLKEO_02043 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AFGLLKEO_02044 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFGLLKEO_02045 6.7e-92 ypoC
AFGLLKEO_02046 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AFGLLKEO_02047 3e-130 dnaD L DNA replication protein DnaD
AFGLLKEO_02048 2e-252 asnS 6.1.1.22 J asparaginyl-tRNA
AFGLLKEO_02049 5.2e-223 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AFGLLKEO_02050 3.6e-82 ypmB S protein conserved in bacteria
AFGLLKEO_02051 6.7e-23 ypmA S Protein of unknown function (DUF4264)
AFGLLKEO_02052 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AFGLLKEO_02053 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AFGLLKEO_02054 5e-159 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AFGLLKEO_02055 2.2e-151 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
AFGLLKEO_02056 4.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AFGLLKEO_02057 1.4e-220 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AFGLLKEO_02058 4.3e-211 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
AFGLLKEO_02059 6.7e-133 bshB1 S proteins, LmbE homologs
AFGLLKEO_02060 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
AFGLLKEO_02061 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AFGLLKEO_02062 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
AFGLLKEO_02063 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
AFGLLKEO_02064 3.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
AFGLLKEO_02065 5.1e-142 ypjB S sporulation protein
AFGLLKEO_02066 2.6e-106 ypjA S membrane
AFGLLKEO_02067 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
AFGLLKEO_02068 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
AFGLLKEO_02069 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
AFGLLKEO_02070 2.9e-78 ypiF S Protein of unknown function (DUF2487)
AFGLLKEO_02071 2.1e-99 ypiB S Belongs to the UPF0302 family
AFGLLKEO_02072 1.4e-234 S COG0457 FOG TPR repeat
AFGLLKEO_02073 6.2e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AFGLLKEO_02074 1.8e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
AFGLLKEO_02075 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AFGLLKEO_02076 6.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AFGLLKEO_02077 6.8e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AFGLLKEO_02078 2.4e-121 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
AFGLLKEO_02079 2e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
AFGLLKEO_02080 2.8e-161 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AFGLLKEO_02081 2.3e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AFGLLKEO_02082 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
AFGLLKEO_02083 1e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AFGLLKEO_02084 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AFGLLKEO_02085 4.5e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
AFGLLKEO_02086 5.4e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
AFGLLKEO_02087 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AFGLLKEO_02088 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
AFGLLKEO_02089 1.6e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
AFGLLKEO_02090 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
AFGLLKEO_02091 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
AFGLLKEO_02092 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AFGLLKEO_02093 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AFGLLKEO_02094 5.6e-135 yphF
AFGLLKEO_02095 3.3e-16 yphE S Protein of unknown function (DUF2768)
AFGLLKEO_02096 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AFGLLKEO_02097 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AFGLLKEO_02098 1.1e-104 yphA
AFGLLKEO_02099 4.7e-08 S YpzI-like protein
AFGLLKEO_02100 8.2e-188 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AFGLLKEO_02101 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
AFGLLKEO_02102 3.3e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AFGLLKEO_02103 1.4e-12 S Family of unknown function (DUF5359)
AFGLLKEO_02104 4.8e-19 ypfA M Flagellar protein YcgR
AFGLLKEO_02105 2.2e-26 ypfA M Flagellar protein YcgR
AFGLLKEO_02106 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
AFGLLKEO_02107 4.9e-162 sleB 3.5.1.28 M Spore cortex-lytic enzyme
AFGLLKEO_02108 8.3e-122 prsW S Involved in the degradation of specific anti-sigma factors
AFGLLKEO_02109 9e-189 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
AFGLLKEO_02110 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
AFGLLKEO_02111 3e-107 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
AFGLLKEO_02112 7.3e-149 ypbG S Calcineurin-like phosphoesterase superfamily domain
AFGLLKEO_02113 2e-85 ypbF S Protein of unknown function (DUF2663)
AFGLLKEO_02114 9.4e-85 ypbE M Lysin motif
AFGLLKEO_02115 9.9e-100 ypbD S metal-dependent membrane protease
AFGLLKEO_02116 1.3e-273 recQ 3.6.4.12 L DNA helicase
AFGLLKEO_02117 2.5e-200 ypbB 5.1.3.1 S protein conserved in bacteria
AFGLLKEO_02118 3.6e-41 fer C Ferredoxin
AFGLLKEO_02119 1.1e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AFGLLKEO_02120 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFGLLKEO_02121 8.8e-201 rsiX
AFGLLKEO_02122 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
AFGLLKEO_02123 0.0 resE 2.7.13.3 T Histidine kinase
AFGLLKEO_02124 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_02125 3.2e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
AFGLLKEO_02126 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
AFGLLKEO_02127 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
AFGLLKEO_02128 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFGLLKEO_02129 1.3e-88 spmB S Spore maturation protein
AFGLLKEO_02130 2e-103 spmA S Spore maturation protein
AFGLLKEO_02131 2.3e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
AFGLLKEO_02132 1.3e-93 ypuI S Protein of unknown function (DUF3907)
AFGLLKEO_02133 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AFGLLKEO_02134 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AFGLLKEO_02136 1.7e-93 ypuF S Domain of unknown function (DUF309)
AFGLLKEO_02137 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFGLLKEO_02138 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
AFGLLKEO_02139 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AFGLLKEO_02140 2e-112 ribE 2.5.1.9 H Riboflavin synthase
AFGLLKEO_02141 8.6e-212 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AFGLLKEO_02142 1.7e-49 ypuD
AFGLLKEO_02143 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
AFGLLKEO_02144 1.3e-82 ccdC1 O Protein of unknown function (DUF1453)
AFGLLKEO_02145 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AFGLLKEO_02146 2.9e-157 ypuA S Secreted protein
AFGLLKEO_02147 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AFGLLKEO_02148 1.4e-270 spoVAF EG Stage V sporulation protein AF
AFGLLKEO_02149 1.8e-110 spoVAEA S stage V sporulation protein
AFGLLKEO_02150 3.8e-57 spoVAEB S stage V sporulation protein
AFGLLKEO_02151 2.9e-190 spoVAD I Stage V sporulation protein AD
AFGLLKEO_02152 2.1e-79 spoVAC S stage V sporulation protein AC
AFGLLKEO_02153 3e-60 spoVAB S Stage V sporulation protein AB
AFGLLKEO_02154 3.7e-111 spoVAA S Stage V sporulation protein AA
AFGLLKEO_02155 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFGLLKEO_02156 1e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
AFGLLKEO_02157 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
AFGLLKEO_02158 4.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
AFGLLKEO_02159 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AFGLLKEO_02160 4.7e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
AFGLLKEO_02161 1.7e-165 xerD L recombinase XerD
AFGLLKEO_02162 3.7e-37 S Protein of unknown function (DUF4227)
AFGLLKEO_02163 1.9e-80 fur P Belongs to the Fur family
AFGLLKEO_02164 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
AFGLLKEO_02166 1.7e-34 yqkK
AFGLLKEO_02167 5.7e-22
AFGLLKEO_02168 7.7e-244 mleA 1.1.1.38 C malic enzyme
AFGLLKEO_02169 5.7e-245 mleN C Na H antiporter
AFGLLKEO_02170 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
AFGLLKEO_02171 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
AFGLLKEO_02172 7e-59 ansR K Transcriptional regulator
AFGLLKEO_02173 1.6e-224 yqxK 3.6.4.12 L DNA helicase
AFGLLKEO_02174 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
AFGLLKEO_02176 3.3e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
AFGLLKEO_02178 3.9e-178 yqkD S COG1073 Hydrolases of the alpha beta superfamily
AFGLLKEO_02179 3.2e-39 yqkC S Protein of unknown function (DUF2552)
AFGLLKEO_02180 2e-61 yqkB S Belongs to the HesB IscA family
AFGLLKEO_02181 2.5e-180 yqkA K GrpB protein
AFGLLKEO_02182 4.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
AFGLLKEO_02183 3.9e-89 yqjY K acetyltransferase
AFGLLKEO_02184 1.3e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFGLLKEO_02185 5.3e-59 S YolD-like protein
AFGLLKEO_02187 2.8e-191 yueF S transporter activity
AFGLLKEO_02189 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFGLLKEO_02190 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
AFGLLKEO_02191 2.1e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
AFGLLKEO_02192 4.1e-144 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
AFGLLKEO_02193 4.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
AFGLLKEO_02194 2.1e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFGLLKEO_02195 1.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
AFGLLKEO_02196 4.4e-241 pksG 2.3.3.10 I synthase
AFGLLKEO_02197 1.2e-221 eryK 1.14.13.154 C Cytochrome P450
AFGLLKEO_02198 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
AFGLLKEO_02199 0.0 Q Polyketide synthase of type I
AFGLLKEO_02200 0.0 pfaA Q Polyketide synthase of type I
AFGLLKEO_02201 0.0 pksJ Q Polyketide synthase of type I
AFGLLKEO_02202 0.0 Q Polyketide synthase of type I
AFGLLKEO_02203 0.0 1.1.1.320 Q Polyketide synthase of type I
AFGLLKEO_02204 0.0 pksJ Q Polyketide synthase of type I
AFGLLKEO_02205 1.9e-130 IQ reductase
AFGLLKEO_02206 3.4e-250 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
AFGLLKEO_02209 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AFGLLKEO_02210 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
AFGLLKEO_02211 2.4e-164 K LysR substrate binding domain
AFGLLKEO_02212 3.8e-51 S GlpM protein
AFGLLKEO_02213 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
AFGLLKEO_02214 1e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AFGLLKEO_02215 6.5e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AFGLLKEO_02216 2.5e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AFGLLKEO_02217 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AFGLLKEO_02218 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFGLLKEO_02219 2.4e-25 yqzJ
AFGLLKEO_02220 1.2e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFGLLKEO_02221 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
AFGLLKEO_02222 3.6e-293 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
AFGLLKEO_02223 1.3e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
AFGLLKEO_02225 1.7e-96 yqjB S protein conserved in bacteria
AFGLLKEO_02226 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
AFGLLKEO_02227 2.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
AFGLLKEO_02228 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
AFGLLKEO_02229 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
AFGLLKEO_02230 1e-75 yqiW S Belongs to the UPF0403 family
AFGLLKEO_02231 4.1e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AFGLLKEO_02232 1.3e-208 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFGLLKEO_02233 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AFGLLKEO_02234 2.3e-168 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
AFGLLKEO_02235 6.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
AFGLLKEO_02236 2e-208 buk 2.7.2.7 C Belongs to the acetokinase family
AFGLLKEO_02237 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
AFGLLKEO_02238 1.1e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
AFGLLKEO_02239 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
AFGLLKEO_02240 3.2e-34 yqzF S Protein of unknown function (DUF2627)
AFGLLKEO_02241 3.3e-161 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AFGLLKEO_02242 5.5e-280 prpD 4.2.1.79 S 2-methylcitrate dehydratase
AFGLLKEO_02243 1.1e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
AFGLLKEO_02244 3.4e-208 mmgC I acyl-CoA dehydrogenase
AFGLLKEO_02245 3e-156 hbdA 1.1.1.157 I Dehydrogenase
AFGLLKEO_02246 3.4e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
AFGLLKEO_02247 5.1e-136 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AFGLLKEO_02248 3.6e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
AFGLLKEO_02249 3.2e-17
AFGLLKEO_02250 1.5e-101 ytaF P Probably functions as a manganese efflux pump
AFGLLKEO_02251 1.8e-113 K Protein of unknown function (DUF1232)
AFGLLKEO_02253 1.4e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
AFGLLKEO_02256 2.7e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFGLLKEO_02257 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
AFGLLKEO_02258 2.3e-240 rseP 3.4.21.116 M Stage IV sporulation protein B
AFGLLKEO_02259 0.0 recN L May be involved in recombinational repair of damaged DNA
AFGLLKEO_02260 3.9e-78 argR K Regulates arginine biosynthesis genes
AFGLLKEO_02261 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
AFGLLKEO_02262 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AFGLLKEO_02263 9.4e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AFGLLKEO_02264 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFGLLKEO_02265 3.2e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFGLLKEO_02266 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AFGLLKEO_02267 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AFGLLKEO_02268 6.2e-67 yqhY S protein conserved in bacteria
AFGLLKEO_02269 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
AFGLLKEO_02270 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AFGLLKEO_02271 2.5e-62 spoIIIAH S SpoIIIAH-like protein
AFGLLKEO_02272 3.4e-118 spoIIIAG S stage III sporulation protein AG
AFGLLKEO_02273 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
AFGLLKEO_02274 6.3e-200 spoIIIAE S stage III sporulation protein AE
AFGLLKEO_02275 2.5e-41 spoIIIAD S Stage III sporulation protein AD
AFGLLKEO_02276 7.6e-29 spoIIIAC S stage III sporulation protein AC
AFGLLKEO_02277 5.8e-86 spoIIIAB S Stage III sporulation protein
AFGLLKEO_02278 1.1e-172 spoIIIAA S stage III sporulation protein AA
AFGLLKEO_02279 1.8e-36 yqhV S Protein of unknown function (DUF2619)
AFGLLKEO_02280 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AFGLLKEO_02281 5e-177 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
AFGLLKEO_02282 3.7e-88 yqhR S Conserved membrane protein YqhR
AFGLLKEO_02283 8e-174 yqhQ S Protein of unknown function (DUF1385)
AFGLLKEO_02284 3.4e-62 yqhP
AFGLLKEO_02285 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
AFGLLKEO_02286 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
AFGLLKEO_02287 4e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
AFGLLKEO_02288 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
AFGLLKEO_02289 1.5e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AFGLLKEO_02290 3.8e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AFGLLKEO_02291 3.6e-210 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
AFGLLKEO_02292 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
AFGLLKEO_02293 2.6e-154 yqhG S Bacterial protein YqhG of unknown function
AFGLLKEO_02294 5.2e-23 sinI S Anti-repressor SinI
AFGLLKEO_02295 7.8e-55 sinR K transcriptional
AFGLLKEO_02296 3.3e-141 tasA S Cell division protein FtsN
AFGLLKEO_02297 3.5e-71 sipW 3.4.21.89 U Signal peptidase
AFGLLKEO_02298 3.5e-123 yqxM
AFGLLKEO_02299 1.3e-54 yqzG S Protein of unknown function (DUF3889)
AFGLLKEO_02300 2.3e-26 yqzE S YqzE-like protein
AFGLLKEO_02301 7.8e-64 S ComG operon protein 7
AFGLLKEO_02302 1.5e-68 comGF U Putative Competence protein ComGF
AFGLLKEO_02303 5.8e-20 comGE
AFGLLKEO_02304 1.6e-73 gspH NU Tfp pilus assembly protein FimT
AFGLLKEO_02305 8.9e-50 comGC U Required for transformation and DNA binding
AFGLLKEO_02306 1.8e-187 comGB NU COG1459 Type II secretory pathway, component PulF
AFGLLKEO_02307 7.8e-202 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AFGLLKEO_02308 4.1e-186 corA P Mg2 transporter protein
AFGLLKEO_02309 3.3e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
AFGLLKEO_02310 2.4e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFGLLKEO_02312 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
AFGLLKEO_02313 3.1e-37 yqgY S Protein of unknown function (DUF2626)
AFGLLKEO_02314 1.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
AFGLLKEO_02315 5.4e-20 yqgW S Protein of unknown function (DUF2759)
AFGLLKEO_02316 6.9e-50 yqgV S Thiamine-binding protein
AFGLLKEO_02317 2.4e-200 yqgU
AFGLLKEO_02318 2.6e-224 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
AFGLLKEO_02319 2.6e-180 glcK 2.7.1.2 G Glucokinase
AFGLLKEO_02320 2.9e-233 nhaC C Na H antiporter
AFGLLKEO_02321 4e-07 yqgO
AFGLLKEO_02322 3.4e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AFGLLKEO_02323 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AFGLLKEO_02324 1.2e-50 yqzD
AFGLLKEO_02325 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AFGLLKEO_02326 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFGLLKEO_02327 1.8e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFGLLKEO_02328 6.3e-157 pstA P Phosphate transport system permease
AFGLLKEO_02329 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
AFGLLKEO_02330 7.6e-158 pstS P Phosphate
AFGLLKEO_02331 2.2e-54 L COG2963 Transposase and inactivated derivatives
AFGLLKEO_02332 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
AFGLLKEO_02333 0.0 pbpA 3.4.16.4 M penicillin-binding protein
AFGLLKEO_02334 2e-228 yqgE EGP Major facilitator superfamily
AFGLLKEO_02335 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
AFGLLKEO_02336 6e-77 yqgC S protein conserved in bacteria
AFGLLKEO_02337 8.7e-131 yqgB S Protein of unknown function (DUF1189)
AFGLLKEO_02338 3.7e-48 yqfZ M LysM domain
AFGLLKEO_02339 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AFGLLKEO_02340 2.3e-52 yqfX S membrane
AFGLLKEO_02341 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
AFGLLKEO_02342 2.9e-72 zur P Belongs to the Fur family
AFGLLKEO_02343 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
AFGLLKEO_02344 9.3e-37 yqfT S Protein of unknown function (DUF2624)
AFGLLKEO_02345 2e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AFGLLKEO_02346 6.7e-248 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AFGLLKEO_02347 6.2e-51 yqfQ S YqfQ-like protein
AFGLLKEO_02348 1.7e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AFGLLKEO_02349 1.7e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AFGLLKEO_02350 5.8e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
AFGLLKEO_02351 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
AFGLLKEO_02352 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AFGLLKEO_02353 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AFGLLKEO_02354 2.1e-88 yaiI S Belongs to the UPF0178 family
AFGLLKEO_02355 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AFGLLKEO_02356 4.5e-112 ccpN K CBS domain
AFGLLKEO_02357 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AFGLLKEO_02358 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AFGLLKEO_02359 4.1e-144 recO L Involved in DNA repair and RecF pathway recombination
AFGLLKEO_02360 1.8e-16 S YqzL-like protein
AFGLLKEO_02361 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AFGLLKEO_02362 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
AFGLLKEO_02363 4.6e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
AFGLLKEO_02364 2.5e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AFGLLKEO_02365 0.0 yqfF S membrane-associated HD superfamily hydrolase
AFGLLKEO_02366 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
AFGLLKEO_02367 1.9e-217 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
AFGLLKEO_02368 9.3e-46 yqfC S sporulation protein YqfC
AFGLLKEO_02369 2.8e-57 yqfB
AFGLLKEO_02370 1.6e-121 yqfA S UPF0365 protein
AFGLLKEO_02371 2e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
AFGLLKEO_02372 1.2e-68 yqeY S Yqey-like protein
AFGLLKEO_02373 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AFGLLKEO_02374 9.3e-159 yqeW P COG1283 Na phosphate symporter
AFGLLKEO_02375 1.2e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
AFGLLKEO_02376 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AFGLLKEO_02377 1.6e-174 prmA J Methylates ribosomal protein L11
AFGLLKEO_02378 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AFGLLKEO_02379 0.0 dnaK O Heat shock 70 kDa protein
AFGLLKEO_02380 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AFGLLKEO_02381 2.3e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AFGLLKEO_02382 2.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
AFGLLKEO_02383 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AFGLLKEO_02384 3.8e-54 yqxA S Protein of unknown function (DUF3679)
AFGLLKEO_02385 1.4e-220 spoIIP M stage II sporulation protein P
AFGLLKEO_02386 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AFGLLKEO_02387 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
AFGLLKEO_02388 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
AFGLLKEO_02389 0.0 comEC S Competence protein ComEC
AFGLLKEO_02390 8e-105 comEB 3.5.4.12 F ComE operon protein 2
AFGLLKEO_02391 7.8e-106 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
AFGLLKEO_02392 2.2e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFGLLKEO_02393 5.8e-140 yqeM Q Methyltransferase
AFGLLKEO_02394 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AFGLLKEO_02395 2.5e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
AFGLLKEO_02396 5.9e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AFGLLKEO_02397 1.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
AFGLLKEO_02398 4.9e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFGLLKEO_02399 2.4e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
AFGLLKEO_02400 2e-94 yqeG S hydrolase of the HAD superfamily
AFGLLKEO_02402 9.1e-141 yqeF E GDSL-like Lipase/Acylhydrolase
AFGLLKEO_02403 2.1e-142 3.5.1.104 G Polysaccharide deacetylase
AFGLLKEO_02404 4.2e-107 yqeD S SNARE associated Golgi protein
AFGLLKEO_02405 3.9e-16 2.3.1.57 K Acetyltransferase (GNAT) domain
AFGLLKEO_02406 3.6e-222 EGP Major facilitator Superfamily
AFGLLKEO_02407 4e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFGLLKEO_02408 1.9e-163 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
AFGLLKEO_02409 3.8e-93 K Transcriptional regulator PadR-like family
AFGLLKEO_02410 3e-69 psiE S Belongs to the PsiE family
AFGLLKEO_02411 4.3e-239 yrkQ T Histidine kinase
AFGLLKEO_02412 1.1e-127 T Transcriptional regulator
AFGLLKEO_02414 1.1e-223 yrkO P Protein of unknown function (DUF418)
AFGLLKEO_02415 3.8e-104 yrkN K Acetyltransferase (GNAT) family
AFGLLKEO_02416 2.9e-101 adk 2.7.4.3 F adenylate kinase activity
AFGLLKEO_02417 4.9e-87 yyaR K acetyltransferase
AFGLLKEO_02418 4.7e-93 yrdA S DinB family
AFGLLKEO_02420 4.4e-149 S hydrolase
AFGLLKEO_02421 5.2e-150 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
AFGLLKEO_02422 2.4e-130 glvR K Helix-turn-helix domain, rpiR family
AFGLLKEO_02423 8.4e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
AFGLLKEO_02424 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
AFGLLKEO_02425 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
AFGLLKEO_02426 2.1e-184 romA S Beta-lactamase superfamily domain
AFGLLKEO_02427 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AFGLLKEO_02428 9.7e-166 yybE K Transcriptional regulator
AFGLLKEO_02429 4.8e-216 ynfM EGP Major facilitator Superfamily
AFGLLKEO_02430 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
AFGLLKEO_02431 9.1e-101 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
AFGLLKEO_02432 1.2e-94 yrhH Q methyltransferase
AFGLLKEO_02434 8e-143 focA P Formate nitrite
AFGLLKEO_02435 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
AFGLLKEO_02436 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
AFGLLKEO_02437 7e-81 yrhD S Protein of unknown function (DUF1641)
AFGLLKEO_02438 4.6e-35 yrhC S YrhC-like protein
AFGLLKEO_02439 1.4e-212 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AFGLLKEO_02440 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
AFGLLKEO_02441 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AFGLLKEO_02442 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
AFGLLKEO_02443 4.1e-27 yrzA S Protein of unknown function (DUF2536)
AFGLLKEO_02444 9.5e-71 yrrS S Protein of unknown function (DUF1510)
AFGLLKEO_02445 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
AFGLLKEO_02446 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AFGLLKEO_02447 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
AFGLLKEO_02448 1.6e-246 yegQ O COG0826 Collagenase and related proteases
AFGLLKEO_02449 2e-174 yegQ O Peptidase U32
AFGLLKEO_02450 2.5e-118 yrrM 2.1.1.104 S O-methyltransferase
AFGLLKEO_02451 5.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AFGLLKEO_02452 7.1e-46 yrzB S Belongs to the UPF0473 family
AFGLLKEO_02453 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AFGLLKEO_02454 1.7e-41 yrzL S Belongs to the UPF0297 family
AFGLLKEO_02455 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AFGLLKEO_02456 5.2e-166 yrrI S AI-2E family transporter
AFGLLKEO_02457 7.5e-132 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
AFGLLKEO_02458 1.5e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
AFGLLKEO_02459 4.2e-110 gluC P ABC transporter
AFGLLKEO_02460 3.1e-108 glnP P ABC transporter
AFGLLKEO_02461 2.1e-08 S Protein of unknown function (DUF3918)
AFGLLKEO_02462 2.9e-30 yrzR
AFGLLKEO_02463 1.8e-83 yrrD S protein conserved in bacteria
AFGLLKEO_02464 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AFGLLKEO_02465 1.7e-18 S COG0457 FOG TPR repeat
AFGLLKEO_02466 2.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AFGLLKEO_02467 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
AFGLLKEO_02468 7.8e-64 cymR K Transcriptional regulator
AFGLLKEO_02469 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
AFGLLKEO_02470 2.5e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
AFGLLKEO_02471 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AFGLLKEO_02472 8.8e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
AFGLLKEO_02475 6.1e-280 lytH 3.5.1.28 M COG3103 SH3 domain protein
AFGLLKEO_02476 1.4e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AFGLLKEO_02477 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AFGLLKEO_02478 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AFGLLKEO_02479 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
AFGLLKEO_02480 5.2e-48 yrvD S Lipopolysaccharide assembly protein A domain
AFGLLKEO_02481 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
AFGLLKEO_02482 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AFGLLKEO_02483 1.3e-50 yrzD S Post-transcriptional regulator
AFGLLKEO_02484 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFGLLKEO_02485 9.5e-110 yrbG S membrane
AFGLLKEO_02486 2.4e-60 yrzE S Protein of unknown function (DUF3792)
AFGLLKEO_02487 3.3e-37 yajC U Preprotein translocase subunit YajC
AFGLLKEO_02488 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AFGLLKEO_02489 1.7e-193 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AFGLLKEO_02490 6.2e-20 yrzS S Protein of unknown function (DUF2905)
AFGLLKEO_02491 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AFGLLKEO_02492 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AFGLLKEO_02493 3.7e-93 bofC S BofC C-terminal domain
AFGLLKEO_02495 1.4e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFGLLKEO_02496 3.9e-149 safA M spore coat assembly protein SafA
AFGLLKEO_02497 8.2e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AFGLLKEO_02498 6.7e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
AFGLLKEO_02499 2.3e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
AFGLLKEO_02500 8.3e-226 nifS 2.8.1.7 E Cysteine desulfurase
AFGLLKEO_02501 1.1e-95 niaR S small molecule binding protein (contains 3H domain)
AFGLLKEO_02502 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
AFGLLKEO_02503 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
AFGLLKEO_02504 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFGLLKEO_02505 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
AFGLLKEO_02506 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AFGLLKEO_02507 3.2e-56 ysxB J ribosomal protein
AFGLLKEO_02508 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
AFGLLKEO_02509 1.2e-160 spoIVFB S Stage IV sporulation protein
AFGLLKEO_02510 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
AFGLLKEO_02511 8e-143 minD D Belongs to the ParA family
AFGLLKEO_02512 3.9e-98 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
AFGLLKEO_02513 1.4e-84 mreD M shape-determining protein
AFGLLKEO_02514 1.2e-157 mreC M Involved in formation and maintenance of cell shape
AFGLLKEO_02515 4e-184 mreB D Rod shape-determining protein MreB
AFGLLKEO_02516 1.8e-127 radC E Belongs to the UPF0758 family
AFGLLKEO_02517 2.4e-101 maf D septum formation protein Maf
AFGLLKEO_02518 1e-139 spoIIB S Sporulation related domain
AFGLLKEO_02519 3.5e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
AFGLLKEO_02520 6.4e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AFGLLKEO_02521 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AFGLLKEO_02522 2.1e-25
AFGLLKEO_02523 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AFGLLKEO_02524 3.5e-242 spoVID M stage VI sporulation protein D
AFGLLKEO_02525 1.2e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
AFGLLKEO_02526 1e-184 hemB 4.2.1.24 H Belongs to the ALAD family
AFGLLKEO_02527 2.7e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
AFGLLKEO_02528 2.4e-175 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
AFGLLKEO_02529 3.6e-146 hemX O cytochrome C
AFGLLKEO_02530 1.4e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AFGLLKEO_02531 1.5e-88 ysxD
AFGLLKEO_02532 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
AFGLLKEO_02533 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AFGLLKEO_02534 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
AFGLLKEO_02535 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AFGLLKEO_02536 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AFGLLKEO_02537 2.4e-189 ysoA H Tetratricopeptide repeat
AFGLLKEO_02538 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AFGLLKEO_02539 6.3e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AFGLLKEO_02540 6.7e-201 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
AFGLLKEO_02541 5.3e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AFGLLKEO_02542 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AFGLLKEO_02543 5.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
AFGLLKEO_02544 0.0 ilvB 2.2.1.6 E Acetolactate synthase
AFGLLKEO_02549 4.8e-93 ysnB S Phosphoesterase
AFGLLKEO_02550 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AFGLLKEO_02551 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AFGLLKEO_02552 2.8e-199 gerM S COG5401 Spore germination protein
AFGLLKEO_02553 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AFGLLKEO_02554 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
AFGLLKEO_02555 2e-30 gerE K Transcriptional regulator
AFGLLKEO_02556 2.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
AFGLLKEO_02557 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
AFGLLKEO_02558 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
AFGLLKEO_02559 4.8e-108 sdhC C succinate dehydrogenase
AFGLLKEO_02560 5.4e-80 yslB S Protein of unknown function (DUF2507)
AFGLLKEO_02561 2.9e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
AFGLLKEO_02562 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AFGLLKEO_02563 2.5e-52 trxA O Belongs to the thioredoxin family
AFGLLKEO_02564 3e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
AFGLLKEO_02565 2.9e-179 etfA C Electron transfer flavoprotein
AFGLLKEO_02566 2e-138 etfB C Electron transfer flavoprotein
AFGLLKEO_02567 1.3e-137 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
AFGLLKEO_02568 9.2e-104 fadR K Transcriptional regulator
AFGLLKEO_02569 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
AFGLLKEO_02570 1e-127 ywbB S Protein of unknown function (DUF2711)
AFGLLKEO_02571 4.7e-67 yshE S membrane
AFGLLKEO_02572 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AFGLLKEO_02573 0.0 polX L COG1796 DNA polymerase IV (family X)
AFGLLKEO_02574 1.6e-83 cvpA S membrane protein, required for colicin V production
AFGLLKEO_02575 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AFGLLKEO_02576 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFGLLKEO_02577 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFGLLKEO_02578 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AFGLLKEO_02579 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFGLLKEO_02580 2e-32 sspI S Belongs to the SspI family
AFGLLKEO_02581 2.4e-206 ysfB KT regulator
AFGLLKEO_02582 7.5e-261 glcD 1.1.3.15 C FAD binding domain
AFGLLKEO_02583 8.6e-259 glcF C Glycolate oxidase
AFGLLKEO_02584 0.0 cstA T Carbon starvation protein
AFGLLKEO_02585 1.2e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
AFGLLKEO_02586 1.2e-144 araQ G transport system permease
AFGLLKEO_02587 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
AFGLLKEO_02588 1.8e-253 araN G carbohydrate transport
AFGLLKEO_02589 7.7e-227 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
AFGLLKEO_02590 1.1e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
AFGLLKEO_02591 3.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
AFGLLKEO_02592 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
AFGLLKEO_02593 3.3e-299 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
AFGLLKEO_02594 1.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
AFGLLKEO_02595 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
AFGLLKEO_02596 9.2e-68 ysdB S Sigma-w pathway protein YsdB
AFGLLKEO_02597 8.2e-44 ysdA S Membrane
AFGLLKEO_02598 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AFGLLKEO_02599 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AFGLLKEO_02600 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AFGLLKEO_02601 1.7e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
AFGLLKEO_02602 3.1e-40 lrgA S effector of murein hydrolase LrgA
AFGLLKEO_02603 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
AFGLLKEO_02604 0.0 lytS 2.7.13.3 T Histidine kinase
AFGLLKEO_02605 5.5e-152 ysaA S HAD-hyrolase-like
AFGLLKEO_02606 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFGLLKEO_02607 2.5e-155 ytxC S YtxC-like family
AFGLLKEO_02608 9.3e-110 ytxB S SNARE associated Golgi protein
AFGLLKEO_02609 4.3e-172 dnaI L Primosomal protein DnaI
AFGLLKEO_02610 4.5e-258 dnaB L Membrane attachment protein
AFGLLKEO_02611 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AFGLLKEO_02612 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AFGLLKEO_02613 1.4e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AFGLLKEO_02614 2e-67 ytcD K Transcriptional regulator
AFGLLKEO_02615 1.2e-206 ytbD EGP Major facilitator Superfamily
AFGLLKEO_02616 5.2e-161 ytbE S reductase
AFGLLKEO_02617 4.7e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AFGLLKEO_02618 9.5e-107 ytaF P Probably functions as a manganese efflux pump
AFGLLKEO_02619 4.1e-158 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AFGLLKEO_02620 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AFGLLKEO_02621 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
AFGLLKEO_02622 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_02623 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
AFGLLKEO_02624 3.1e-242 icd 1.1.1.42 C isocitrate
AFGLLKEO_02625 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
AFGLLKEO_02626 7.7e-49 yjdF S Protein of unknown function (DUF2992)
AFGLLKEO_02627 1.1e-72 yeaL S membrane
AFGLLKEO_02628 3.6e-194 ytvI S sporulation integral membrane protein YtvI
AFGLLKEO_02629 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
AFGLLKEO_02630 6.8e-296 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AFGLLKEO_02631 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AFGLLKEO_02632 6.2e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
AFGLLKEO_02633 6.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AFGLLKEO_02634 2.6e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
AFGLLKEO_02635 0.0 dnaE 2.7.7.7 L DNA polymerase
AFGLLKEO_02636 3.2e-56 ytrH S Sporulation protein YtrH
AFGLLKEO_02637 5.1e-87 ytrI
AFGLLKEO_02638 4.4e-23
AFGLLKEO_02639 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
AFGLLKEO_02640 8.2e-48 ytpI S YtpI-like protein
AFGLLKEO_02641 7.5e-239 ytoI K transcriptional regulator containing CBS domains
AFGLLKEO_02642 1.1e-129 ytkL S Belongs to the UPF0173 family
AFGLLKEO_02643 4.5e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFGLLKEO_02645 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
AFGLLKEO_02646 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AFGLLKEO_02647 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
AFGLLKEO_02648 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFGLLKEO_02649 3.6e-185 ytxK 2.1.1.72 L DNA methylase
AFGLLKEO_02650 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AFGLLKEO_02651 1.6e-60 ytfJ S Sporulation protein YtfJ
AFGLLKEO_02652 1.1e-119 ytfI S Protein of unknown function (DUF2953)
AFGLLKEO_02653 4.5e-88 yteJ S RDD family
AFGLLKEO_02654 2.9e-182 sppA OU signal peptide peptidase SppA
AFGLLKEO_02655 1.5e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFGLLKEO_02656 0.0 ytcJ S amidohydrolase
AFGLLKEO_02657 1.6e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
AFGLLKEO_02658 3.9e-31 sspB S spore protein
AFGLLKEO_02659 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AFGLLKEO_02660 1.7e-210 iscS2 2.8.1.7 E Cysteine desulfurase
AFGLLKEO_02661 1.8e-240 braB E Component of the transport system for branched-chain amino acids
AFGLLKEO_02662 1e-264 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AFGLLKEO_02663 1.9e-155 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
AFGLLKEO_02664 4.1e-110 yttP K Transcriptional regulator
AFGLLKEO_02665 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
AFGLLKEO_02666 9.2e-285 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
AFGLLKEO_02667 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AFGLLKEO_02668 1.7e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
AFGLLKEO_02669 2.7e-105 yokH G SMI1 / KNR4 family
AFGLLKEO_02671 1.3e-102
AFGLLKEO_02673 1.2e-88 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
AFGLLKEO_02675 1.4e-28 S Phage-like element PBSX protein XtrA
AFGLLKEO_02676 5.2e-30
AFGLLKEO_02677 1.8e-33 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AFGLLKEO_02678 2.3e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AFGLLKEO_02679 7.3e-09
AFGLLKEO_02680 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
AFGLLKEO_02682 2.4e-141 E GDSL-like Lipase/Acylhydrolase family
AFGLLKEO_02683 5.1e-151 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFGLLKEO_02684 4.4e-149 K Transcriptional regulator
AFGLLKEO_02685 5.2e-125 azlC E AzlC protein
AFGLLKEO_02686 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
AFGLLKEO_02687 4.2e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AFGLLKEO_02688 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
AFGLLKEO_02689 2.8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
AFGLLKEO_02690 2.5e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
AFGLLKEO_02691 2.3e-231 acuC BQ histone deacetylase
AFGLLKEO_02692 7.4e-121 motS N Flagellar motor protein
AFGLLKEO_02693 3e-145 motA N flagellar motor
AFGLLKEO_02694 2.9e-182 ccpA K catabolite control protein A
AFGLLKEO_02695 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
AFGLLKEO_02696 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
AFGLLKEO_02697 1.7e-16 ytxH S COG4980 Gas vesicle protein
AFGLLKEO_02698 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AFGLLKEO_02699 9.9e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AFGLLKEO_02700 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
AFGLLKEO_02701 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFGLLKEO_02702 3.7e-148 ytpQ S Belongs to the UPF0354 family
AFGLLKEO_02703 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AFGLLKEO_02704 2.7e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
AFGLLKEO_02705 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
AFGLLKEO_02706 1.7e-51 ytzB S small secreted protein
AFGLLKEO_02707 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
AFGLLKEO_02708 7.1e-166 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
AFGLLKEO_02709 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AFGLLKEO_02710 9.2e-46 ytzH S YtzH-like protein
AFGLLKEO_02711 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
AFGLLKEO_02712 7.7e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
AFGLLKEO_02713 9.5e-172 ytlQ
AFGLLKEO_02714 2.8e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AFGLLKEO_02715 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFGLLKEO_02716 1.4e-272 pepV 3.5.1.18 E Dipeptidase
AFGLLKEO_02717 4.1e-229 pbuO S permease
AFGLLKEO_02718 1.5e-219 ythQ U Bacterial ABC transporter protein EcsB
AFGLLKEO_02719 3.4e-129 ythP V ABC transporter
AFGLLKEO_02720 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
AFGLLKEO_02721 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFGLLKEO_02722 2e-294 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFGLLKEO_02723 1.5e-236 ytfP S HI0933-like protein
AFGLLKEO_02724 4.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
AFGLLKEO_02725 9e-26 yteV S Sporulation protein Cse60
AFGLLKEO_02726 3e-187 msmR K Transcriptional regulator
AFGLLKEO_02727 1.1e-247 msmE G Bacterial extracellular solute-binding protein
AFGLLKEO_02728 3.3e-169 amyD G Binding-protein-dependent transport system inner membrane component
AFGLLKEO_02729 4.8e-143 amyC P ABC transporter (permease)
AFGLLKEO_02730 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
AFGLLKEO_02731 2.4e-86 M Acetyltransferase (GNAT) domain
AFGLLKEO_02732 5.6e-52 ytwF P Sulfurtransferase
AFGLLKEO_02733 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFGLLKEO_02734 1.2e-52 ytvB S Protein of unknown function (DUF4257)
AFGLLKEO_02735 6.6e-140 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
AFGLLKEO_02736 5.6e-209 yttB EGP Major facilitator Superfamily
AFGLLKEO_02737 1.7e-131 ywaF S Integral membrane protein
AFGLLKEO_02738 0.0 bceB V ABC transporter (permease)
AFGLLKEO_02739 5.8e-135 bceA V ABC transporter, ATP-binding protein
AFGLLKEO_02740 1.3e-171 T PhoQ Sensor
AFGLLKEO_02741 2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_02742 3.7e-222 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
AFGLLKEO_02743 1.3e-125 ytrE V ABC transporter, ATP-binding protein
AFGLLKEO_02744 2.5e-162
AFGLLKEO_02745 8.8e-176 P ABC-2 family transporter protein
AFGLLKEO_02746 1e-176 S ABC-2 family transporter protein
AFGLLKEO_02747 3.8e-162 ytrB P abc transporter atp-binding protein
AFGLLKEO_02748 3.9e-66 ytrA K GntR family transcriptional regulator
AFGLLKEO_02750 7.4e-40 ytzC S Protein of unknown function (DUF2524)
AFGLLKEO_02751 0.0 IQ AMP-binding enzyme
AFGLLKEO_02752 1e-204 K helix_turn_helix, Arsenical Resistance Operon Repressor
AFGLLKEO_02753 0.0 Q Polyketide synthase of type I
AFGLLKEO_02754 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_02755 3.1e-189 C Nitroreductase
AFGLLKEO_02756 8.6e-133 nrsA Q Thioesterase domain
AFGLLKEO_02757 2.2e-288 norB EGP COG0477 Permeases of the major facilitator superfamily
AFGLLKEO_02758 2.1e-190 yhcC S Fe-S oxidoreductase
AFGLLKEO_02759 3.9e-107 ytqB J Putative rRNA methylase
AFGLLKEO_02761 8.6e-145 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
AFGLLKEO_02762 4.4e-213 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
AFGLLKEO_02763 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
AFGLLKEO_02764 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AFGLLKEO_02765 1.9e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
AFGLLKEO_02766 0.0 asnB 6.3.5.4 E Asparagine synthase
AFGLLKEO_02767 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AFGLLKEO_02768 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AFGLLKEO_02769 1.6e-38 ytmB S Protein of unknown function (DUF2584)
AFGLLKEO_02770 3.2e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
AFGLLKEO_02771 6.6e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
AFGLLKEO_02772 2.9e-145 ytlC P ABC transporter
AFGLLKEO_02773 5.8e-141 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
AFGLLKEO_02774 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
AFGLLKEO_02775 6e-62 ytkC S Bacteriophage holin family
AFGLLKEO_02776 3.2e-77 dps P Belongs to the Dps family
AFGLLKEO_02778 7.2e-77 ytkA S YtkA-like
AFGLLKEO_02779 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AFGLLKEO_02780 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AFGLLKEO_02781 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
AFGLLKEO_02782 1.6e-41 rpmE2 J Ribosomal protein L31
AFGLLKEO_02783 6.8e-240 cydA 1.10.3.14 C oxidase, subunit
AFGLLKEO_02784 4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
AFGLLKEO_02785 2.3e-24 S Domain of Unknown Function (DUF1540)
AFGLLKEO_02786 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
AFGLLKEO_02787 3.3e-280 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
AFGLLKEO_02788 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AFGLLKEO_02789 1.7e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
AFGLLKEO_02790 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AFGLLKEO_02791 3.1e-275 menF 5.4.4.2 HQ Isochorismate synthase
AFGLLKEO_02792 2e-132 dksA T COG1734 DnaK suppressor protein
AFGLLKEO_02793 6.2e-79 tspO T membrane
AFGLLKEO_02802 7.8e-08
AFGLLKEO_02803 1.3e-09
AFGLLKEO_02810 1.6e-08
AFGLLKEO_02815 3.4e-39 S COG NOG14552 non supervised orthologous group
AFGLLKEO_02816 3.3e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
AFGLLKEO_02817 7e-180 yuaG 3.4.21.72 S protein conserved in bacteria
AFGLLKEO_02818 1.3e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
AFGLLKEO_02819 5.1e-84 yuaE S DinB superfamily
AFGLLKEO_02820 6.5e-110 yuaD S MOSC domain
AFGLLKEO_02821 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
AFGLLKEO_02822 1.2e-285 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
AFGLLKEO_02823 2.7e-97 yuaC K Belongs to the GbsR family
AFGLLKEO_02824 2.1e-94 yuaB
AFGLLKEO_02825 1.1e-121 ktrA P COG0569 K transport systems, NAD-binding component
AFGLLKEO_02826 6.7e-148 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AFGLLKEO_02827 2.4e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AFGLLKEO_02828 1.3e-124 G Cupin
AFGLLKEO_02829 6.2e-54 yjcN
AFGLLKEO_02831 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AFGLLKEO_02832 9e-196 yubA S transporter activity
AFGLLKEO_02833 1.9e-186 ygjR S Oxidoreductase
AFGLLKEO_02834 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
AFGLLKEO_02835 1e-239 mcpA NT chemotaxis protein
AFGLLKEO_02836 1.1e-225 mcpA NT chemotaxis protein
AFGLLKEO_02837 1.9e-241 mcpA NT chemotaxis protein
AFGLLKEO_02838 1.7e-223 mcpA NT chemotaxis protein
AFGLLKEO_02839 9e-141 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
AFGLLKEO_02840 4.8e-41
AFGLLKEO_02841 1.8e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
AFGLLKEO_02842 2.8e-78 yugU S Uncharacterised protein family UPF0047
AFGLLKEO_02843 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
AFGLLKEO_02844 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
AFGLLKEO_02845 8.3e-117 yugP S Zn-dependent protease
AFGLLKEO_02846 4.5e-18
AFGLLKEO_02847 1.1e-26 mstX S Membrane-integrating protein Mistic
AFGLLKEO_02848 6.3e-182 yugO P COG1226 Kef-type K transport systems
AFGLLKEO_02849 1.3e-72 yugN S YugN-like family
AFGLLKEO_02851 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
AFGLLKEO_02852 2.1e-97 S NADPH-dependent FMN reductase
AFGLLKEO_02853 6.5e-119 ycaC Q Isochorismatase family
AFGLLKEO_02854 7.4e-230 yugK C Dehydrogenase
AFGLLKEO_02855 1.2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
AFGLLKEO_02856 1.8e-34 yuzA S Domain of unknown function (DUF378)
AFGLLKEO_02857 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
AFGLLKEO_02858 1.2e-211 yugH 2.6.1.1 E Aminotransferase
AFGLLKEO_02859 2e-83 alaR K Transcriptional regulator
AFGLLKEO_02860 3.8e-156 yugF I Hydrolase
AFGLLKEO_02861 1.4e-40 yugE S Domain of unknown function (DUF1871)
AFGLLKEO_02862 8.4e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
AFGLLKEO_02863 5.6e-231 T PhoQ Sensor
AFGLLKEO_02864 3.7e-69 kapB G Kinase associated protein B
AFGLLKEO_02865 4.5e-118 kapD L the KinA pathway to sporulation
AFGLLKEO_02866 1.5e-185 yuxJ EGP Major facilitator Superfamily
AFGLLKEO_02867 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
AFGLLKEO_02868 1.7e-72 yuxK S protein conserved in bacteria
AFGLLKEO_02869 9.3e-74 yufK S Family of unknown function (DUF5366)
AFGLLKEO_02870 1.5e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
AFGLLKEO_02871 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
AFGLLKEO_02872 8.3e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
AFGLLKEO_02873 4.5e-288 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
AFGLLKEO_02874 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
AFGLLKEO_02875 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
AFGLLKEO_02876 1.8e-12
AFGLLKEO_02877 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
AFGLLKEO_02878 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFGLLKEO_02879 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFGLLKEO_02880 1.2e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFGLLKEO_02881 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFGLLKEO_02882 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFGLLKEO_02883 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
AFGLLKEO_02884 3.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
AFGLLKEO_02885 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFGLLKEO_02886 0.0 comP 2.7.13.3 T Histidine kinase
AFGLLKEO_02888 6.3e-154 comQ H Polyprenyl synthetase
AFGLLKEO_02890 3e-54 yuzC
AFGLLKEO_02891 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
AFGLLKEO_02892 2.5e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AFGLLKEO_02893 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
AFGLLKEO_02894 7.2e-68 yueI S Protein of unknown function (DUF1694)
AFGLLKEO_02895 2.8e-38 yueH S YueH-like protein
AFGLLKEO_02896 6.4e-34 yueG S Spore germination protein gerPA/gerPF
AFGLLKEO_02897 3e-188 yueF S transporter activity
AFGLLKEO_02898 1.6e-22 S Protein of unknown function (DUF2642)
AFGLLKEO_02899 3.7e-96 yueE S phosphohydrolase
AFGLLKEO_02900 5.8e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFGLLKEO_02901 1.8e-78 yueC S Family of unknown function (DUF5383)
AFGLLKEO_02902 0.0 esaA S type VII secretion protein EsaA
AFGLLKEO_02903 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
AFGLLKEO_02904 7.4e-207 essB S WXG100 protein secretion system (Wss), protein YukC
AFGLLKEO_02905 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
AFGLLKEO_02906 3.3e-46 esxA S Belongs to the WXG100 family
AFGLLKEO_02907 4.5e-230 yukF QT Transcriptional regulator
AFGLLKEO_02908 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
AFGLLKEO_02909 6.8e-135 yukJ S Uncharacterized conserved protein (DUF2278)
AFGLLKEO_02910 1.3e-36 mbtH S MbtH-like protein
AFGLLKEO_02911 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_02912 6.3e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
AFGLLKEO_02913 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
AFGLLKEO_02914 1.1e-225 entC 5.4.4.2 HQ Isochorismate synthase
AFGLLKEO_02915 1.1e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFGLLKEO_02916 1.5e-166 besA S Putative esterase
AFGLLKEO_02917 1.1e-120 yuiH S Oxidoreductase molybdopterin binding domain
AFGLLKEO_02918 1.1e-101 bioY S Biotin biosynthesis protein
AFGLLKEO_02919 3.7e-209 yuiF S antiporter
AFGLLKEO_02920 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AFGLLKEO_02921 9.1e-78 yuiD S protein conserved in bacteria
AFGLLKEO_02922 1.4e-118 yuiC S protein conserved in bacteria
AFGLLKEO_02923 9.9e-28 yuiB S Putative membrane protein
AFGLLKEO_02924 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
AFGLLKEO_02925 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
AFGLLKEO_02927 4.2e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AFGLLKEO_02928 4.8e-29
AFGLLKEO_02929 3.7e-72 CP Membrane
AFGLLKEO_02930 1.5e-124 V ABC transporter
AFGLLKEO_02932 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
AFGLLKEO_02934 2.9e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
AFGLLKEO_02935 7.8e-140 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
AFGLLKEO_02936 1.1e-62 erpA S Belongs to the HesB IscA family
AFGLLKEO_02937 5.7e-163 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AFGLLKEO_02938 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AFGLLKEO_02939 2.4e-39 yuzB S Belongs to the UPF0349 family
AFGLLKEO_02940 8.5e-209 yutJ 1.6.99.3 C NADH dehydrogenase
AFGLLKEO_02941 4.7e-57 yuzD S protein conserved in bacteria
AFGLLKEO_02942 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
AFGLLKEO_02943 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
AFGLLKEO_02944 1e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AFGLLKEO_02945 4e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AFGLLKEO_02946 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
AFGLLKEO_02947 1.4e-197 yutH S Spore coat protein
AFGLLKEO_02948 3e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
AFGLLKEO_02949 8.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AFGLLKEO_02950 8.6e-75 yutE S Protein of unknown function DUF86
AFGLLKEO_02951 1.7e-47 yutD S protein conserved in bacteria
AFGLLKEO_02952 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AFGLLKEO_02953 5.8e-196 lytH M Peptidase, M23
AFGLLKEO_02954 6e-132 yunB S Sporulation protein YunB (Spo_YunB)
AFGLLKEO_02955 2.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
AFGLLKEO_02956 1.8e-145 yunE S membrane transporter protein
AFGLLKEO_02957 1.3e-170 yunF S Protein of unknown function DUF72
AFGLLKEO_02958 4.7e-63 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
AFGLLKEO_02959 8.8e-267 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
AFGLLKEO_02960 2.1e-304 pucR QT COG2508 Regulator of polyketide synthase expression
AFGLLKEO_02961 4.3e-74
AFGLLKEO_02963 1.5e-214 blt EGP Major facilitator Superfamily
AFGLLKEO_02964 4.9e-240 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
AFGLLKEO_02965 1.9e-239 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
AFGLLKEO_02966 1.1e-169 bsn L Ribonuclease
AFGLLKEO_02967 2.3e-209 msmX P Belongs to the ABC transporter superfamily
AFGLLKEO_02968 1.2e-134 yurK K UTRA
AFGLLKEO_02969 6.3e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
AFGLLKEO_02970 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
AFGLLKEO_02971 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
AFGLLKEO_02972 3.3e-247 yurO G COG1653 ABC-type sugar transport system, periplasmic component
AFGLLKEO_02973 1.9e-186 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
AFGLLKEO_02974 1.2e-166 K helix_turn_helix, mercury resistance
AFGLLKEO_02977 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
AFGLLKEO_02978 3.2e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
AFGLLKEO_02979 1.8e-130 Q ubiE/COQ5 methyltransferase family
AFGLLKEO_02980 1.5e-85 yncE S Protein of unknown function (DUF2691)
AFGLLKEO_02981 2e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
AFGLLKEO_02982 3e-270 sufB O FeS cluster assembly
AFGLLKEO_02983 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
AFGLLKEO_02984 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AFGLLKEO_02985 7e-245 sufD O assembly protein SufD
AFGLLKEO_02986 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
AFGLLKEO_02987 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AFGLLKEO_02988 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
AFGLLKEO_02989 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
AFGLLKEO_02990 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFGLLKEO_02991 5e-57 yusD S SCP-2 sterol transfer family
AFGLLKEO_02992 1.6e-54 yusE CO Thioredoxin
AFGLLKEO_02993 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
AFGLLKEO_02994 1.3e-40 yusG S Protein of unknown function (DUF2553)
AFGLLKEO_02995 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
AFGLLKEO_02996 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
AFGLLKEO_02997 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
AFGLLKEO_02998 1.1e-217 fadA 2.3.1.16 I Belongs to the thiolase family
AFGLLKEO_02999 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
AFGLLKEO_03000 3.6e-168 fadM E Proline dehydrogenase
AFGLLKEO_03001 1.4e-43
AFGLLKEO_03002 1.1e-53 yusN M Coat F domain
AFGLLKEO_03003 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
AFGLLKEO_03004 8.1e-288 yusP P Major facilitator superfamily
AFGLLKEO_03005 3.1e-68 yusQ S Tautomerase enzyme
AFGLLKEO_03006 1.4e-133 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFGLLKEO_03007 1e-159 yusT K LysR substrate binding domain
AFGLLKEO_03008 4.2e-161 ywbI2 K Transcriptional regulator
AFGLLKEO_03009 4.1e-141 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
AFGLLKEO_03010 1.7e-190 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFGLLKEO_03011 3.3e-39 yusU S Protein of unknown function (DUF2573)
AFGLLKEO_03012 1.4e-150 yusV 3.6.3.34 HP ABC transporter
AFGLLKEO_03013 7.2e-45 S YusW-like protein
AFGLLKEO_03014 0.0 pepF2 E COG1164 Oligoendopeptidase F
AFGLLKEO_03015 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFGLLKEO_03016 6.7e-81 dps P Belongs to the Dps family
AFGLLKEO_03017 7.5e-242 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFGLLKEO_03018 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_03019 2.5e-253 cssS 2.7.13.3 T PhoQ Sensor
AFGLLKEO_03020 3.4e-24
AFGLLKEO_03021 2.7e-158 yuxN K Transcriptional regulator
AFGLLKEO_03022 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AFGLLKEO_03023 6.6e-24 S Protein of unknown function (DUF3970)
AFGLLKEO_03024 2.2e-260 gerAA EG Spore germination protein
AFGLLKEO_03025 2e-189 gerAB E Spore germination protein
AFGLLKEO_03026 7.3e-211 gerAC S Spore germination B3/ GerAC like, C-terminal
AFGLLKEO_03027 1.5e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFGLLKEO_03028 1e-193 vraS 2.7.13.3 T Histidine kinase
AFGLLKEO_03029 1.7e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
AFGLLKEO_03030 2.7e-144 liaG S Putative adhesin
AFGLLKEO_03031 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
AFGLLKEO_03032 3.3e-46 liaI S membrane
AFGLLKEO_03033 4.7e-230 yvqJ EGP Major facilitator Superfamily
AFGLLKEO_03034 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
AFGLLKEO_03035 2.1e-227 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
AFGLLKEO_03036 6.7e-182 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFGLLKEO_03037 1.1e-167 yvrC P ABC transporter substrate-binding protein
AFGLLKEO_03038 1.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFGLLKEO_03039 2e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
AFGLLKEO_03040 0.0 T PhoQ Sensor
AFGLLKEO_03041 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_03042 1.1e-36
AFGLLKEO_03043 9.9e-103 yvrI K RNA polymerase
AFGLLKEO_03044 1.6e-15 S YvrJ protein family
AFGLLKEO_03045 5.4e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
AFGLLKEO_03046 4.4e-68 yvrL S Regulatory protein YrvL
AFGLLKEO_03047 4.8e-148 fhuC 3.6.3.34 HP ABC transporter
AFGLLKEO_03048 1.1e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFGLLKEO_03049 6.6e-185 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFGLLKEO_03050 4e-178 fhuD P ABC transporter
AFGLLKEO_03051 1.3e-236 yvsH E Arginine ornithine antiporter
AFGLLKEO_03052 1e-13 S Small spore protein J (Spore_SspJ)
AFGLLKEO_03053 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
AFGLLKEO_03054 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AFGLLKEO_03055 1.8e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
AFGLLKEO_03056 2.2e-140 modA P COG0725 ABC-type molybdate transport system, periplasmic component
AFGLLKEO_03057 2.7e-99 modB P COG4149 ABC-type molybdate transport system, permease component
AFGLLKEO_03058 4.4e-115 yfiK K Regulator
AFGLLKEO_03059 4.9e-183 T Histidine kinase
AFGLLKEO_03060 1.9e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
AFGLLKEO_03061 2.5e-195 yfiM V ABC-2 type transporter
AFGLLKEO_03062 1.4e-201 yfiN V COG0842 ABC-type multidrug transport system, permease component
AFGLLKEO_03063 5e-156 yvgN S reductase
AFGLLKEO_03064 4.9e-87 yvgO
AFGLLKEO_03065 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
AFGLLKEO_03066 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
AFGLLKEO_03067 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AFGLLKEO_03068 0.0 helD 3.6.4.12 L DNA helicase
AFGLLKEO_03069 9.1e-107 yvgT S membrane
AFGLLKEO_03070 6.1e-143 S Metallo-peptidase family M12
AFGLLKEO_03071 2e-73 bdbC O Required for disulfide bond formation in some proteins
AFGLLKEO_03072 1.2e-102 bdbD O Thioredoxin
AFGLLKEO_03073 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
AFGLLKEO_03074 0.0 copA 3.6.3.54 P P-type ATPase
AFGLLKEO_03075 2.6e-29 copZ P Heavy-metal-associated domain
AFGLLKEO_03076 3.7e-48 csoR S transcriptional
AFGLLKEO_03077 7.3e-197 yvaA 1.1.1.371 S Oxidoreductase
AFGLLKEO_03078 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AFGLLKEO_03079 1.1e-163 K Helix-turn-helix XRE-family like proteins
AFGLLKEO_03080 2.9e-221 ynfM EGP Major Facilitator Superfamily
AFGLLKEO_03081 1.2e-70 4.1.1.44 S Carboxymuconolactone decarboxylase family
AFGLLKEO_03082 1.4e-147 S Amidohydrolase
AFGLLKEO_03083 4.7e-257 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFGLLKEO_03084 5.9e-48 ytnI O COG0695 Glutaredoxin and related proteins
AFGLLKEO_03085 2.9e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFGLLKEO_03086 6.6e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
AFGLLKEO_03087 1.3e-120 tcyM U Binding-protein-dependent transport system inner membrane component
AFGLLKEO_03088 1.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
AFGLLKEO_03089 9.9e-149 tcyK M Bacterial periplasmic substrate-binding proteins
AFGLLKEO_03090 7.4e-132 ytmJ ET Bacterial periplasmic substrate-binding proteins
AFGLLKEO_03091 1.7e-101 ytmI K Acetyltransferase (GNAT) domain
AFGLLKEO_03092 4.8e-165 ytlI K LysR substrate binding domain
AFGLLKEO_03093 1.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFGLLKEO_03094 2.9e-53 yrdF K ribonuclease inhibitor
AFGLLKEO_03096 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AFGLLKEO_03097 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AFGLLKEO_03098 7.4e-143 est 3.1.1.1 S Carboxylesterase
AFGLLKEO_03099 4.8e-24 secG U Preprotein translocase subunit SecG
AFGLLKEO_03100 6e-35 yvzC K Transcriptional
AFGLLKEO_03101 1e-69 K transcriptional
AFGLLKEO_03102 2.7e-73 yvaO K Cro/C1-type HTH DNA-binding domain
AFGLLKEO_03103 8.8e-53 yodB K transcriptional
AFGLLKEO_03104 2.2e-260 T His Kinase A (phosphoacceptor) domain
AFGLLKEO_03105 2e-123 K Transcriptional regulatory protein, C terminal
AFGLLKEO_03106 1.9e-141 mutG S ABC-2 family transporter protein
AFGLLKEO_03107 2.5e-127 spaE S ABC-2 family transporter protein
AFGLLKEO_03108 2.5e-127 mutF V ABC transporter, ATP-binding protein
AFGLLKEO_03109 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
AFGLLKEO_03110 2.6e-174 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AFGLLKEO_03111 5.4e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
AFGLLKEO_03112 3.4e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
AFGLLKEO_03113 4.3e-76 yvbF K Belongs to the GbsR family
AFGLLKEO_03114 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
AFGLLKEO_03115 2.2e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AFGLLKEO_03116 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
AFGLLKEO_03117 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
AFGLLKEO_03118 1.9e-98 yvbF K Belongs to the GbsR family
AFGLLKEO_03119 5.2e-105 yvbG U UPF0056 membrane protein
AFGLLKEO_03120 4.5e-121 exoY M Membrane
AFGLLKEO_03121 0.0 tcaA S response to antibiotic
AFGLLKEO_03122 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
AFGLLKEO_03123 3.5e-214 EGP Major facilitator Superfamily
AFGLLKEO_03124 2.2e-181
AFGLLKEO_03125 1.2e-126 S GlcNAc-PI de-N-acetylase
AFGLLKEO_03126 2.5e-143 C WbqC-like protein family
AFGLLKEO_03127 1.2e-150 M Protein involved in cellulose biosynthesis
AFGLLKEO_03128 2.2e-240 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AFGLLKEO_03129 8.6e-173 5.1.3.2 M GDP-mannose 4,6 dehydratase
AFGLLKEO_03130 1.3e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
AFGLLKEO_03131 2.8e-257 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFGLLKEO_03132 7.8e-241 ywaD 3.4.11.10, 3.4.11.6 S PA domain
AFGLLKEO_03133 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AFGLLKEO_03134 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
AFGLLKEO_03135 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AFGLLKEO_03136 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AFGLLKEO_03137 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AFGLLKEO_03138 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
AFGLLKEO_03140 7.4e-253 araE EGP Major facilitator Superfamily
AFGLLKEO_03141 3.4e-205 araR K transcriptional
AFGLLKEO_03142 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFGLLKEO_03144 2.1e-157 yvbU K Transcriptional regulator
AFGLLKEO_03145 9.1e-159 yvbV EG EamA-like transporter family
AFGLLKEO_03146 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
AFGLLKEO_03147 4e-261
AFGLLKEO_03148 1.7e-184 purR7 5.1.1.1 K Transcriptional regulator
AFGLLKEO_03149 6.9e-116 yyaS S Membrane
AFGLLKEO_03150 6.1e-168 3.1.3.104 S hydrolases of the HAD superfamily
AFGLLKEO_03151 9.1e-153 ybbH_1 K RpiR family transcriptional regulator
AFGLLKEO_03152 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
AFGLLKEO_03153 4.3e-226 gntP EG COG2610 H gluconate symporter and related permeases
AFGLLKEO_03154 3.6e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
AFGLLKEO_03155 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
AFGLLKEO_03156 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
AFGLLKEO_03157 2e-227 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFGLLKEO_03158 1.6e-121 yvfI K COG2186 Transcriptional regulators
AFGLLKEO_03159 3.4e-305 yvfH C L-lactate permease
AFGLLKEO_03160 1.8e-245 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
AFGLLKEO_03161 1.6e-32 yvfG S YvfG protein
AFGLLKEO_03162 3.6e-190 yvfF GM Exopolysaccharide biosynthesis protein
AFGLLKEO_03163 5.7e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
AFGLLKEO_03164 1.1e-57 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
AFGLLKEO_03165 3.4e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
AFGLLKEO_03166 8.2e-274 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFGLLKEO_03167 7.8e-199 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
AFGLLKEO_03168 4.7e-207 epsI GM pyruvyl transferase
AFGLLKEO_03169 1.2e-196 epsH GT2 S Glycosyltransferase like family 2
AFGLLKEO_03170 4.1e-206 epsG S EpsG family
AFGLLKEO_03171 3.1e-217 epsF GT4 M Glycosyl transferases group 1
AFGLLKEO_03172 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
AFGLLKEO_03173 1.7e-223 epsD GT4 M Glycosyl transferase 4-like
AFGLLKEO_03174 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
AFGLLKEO_03175 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
AFGLLKEO_03176 2.2e-120 ywqC M biosynthesis protein
AFGLLKEO_03177 5.1e-78 slr K transcriptional
AFGLLKEO_03178 1.6e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
AFGLLKEO_03179 1.4e-98 ywjB H RibD C-terminal domain
AFGLLKEO_03180 4e-113 yyaS S Membrane
AFGLLKEO_03181 6.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFGLLKEO_03182 5.5e-94 padC Q Phenolic acid decarboxylase
AFGLLKEO_03183 2e-16 S Protein of unknown function (DUF1433)
AFGLLKEO_03184 4.8e-41 S Protein of unknown function (DUF1433)
AFGLLKEO_03185 1.6e-46 I Pfam Lipase (class 3)
AFGLLKEO_03186 1.8e-16 S Protein of unknown function (DUF1433)
AFGLLKEO_03187 5.9e-274 I Pfam Lipase (class 3)
AFGLLKEO_03188 1.8e-34
AFGLLKEO_03190 9.4e-299 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
AFGLLKEO_03191 7.3e-220 rafB P LacY proton/sugar symporter
AFGLLKEO_03192 1e-184 scrR K transcriptional
AFGLLKEO_03193 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AFGLLKEO_03194 6.7e-164 yraN K Transcriptional regulator
AFGLLKEO_03195 4.5e-216 yraM S PrpF protein
AFGLLKEO_03196 1.6e-252 EGP Sugar (and other) transporter
AFGLLKEO_03197 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
AFGLLKEO_03198 2.3e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
AFGLLKEO_03199 3.9e-282 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
AFGLLKEO_03200 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
AFGLLKEO_03201 5e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFGLLKEO_03202 1.6e-79 M Ribonuclease
AFGLLKEO_03203 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
AFGLLKEO_03204 1.2e-36 crh G Phosphocarrier protein Chr
AFGLLKEO_03205 3.1e-170 whiA K May be required for sporulation
AFGLLKEO_03206 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AFGLLKEO_03207 1.1e-166 rapZ S Displays ATPase and GTPase activities
AFGLLKEO_03208 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
AFGLLKEO_03209 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AFGLLKEO_03210 2.7e-125 usp CBM50 M protein conserved in bacteria
AFGLLKEO_03211 1e-276 S COG0457 FOG TPR repeat
AFGLLKEO_03212 2.9e-193 sasA T Histidine kinase
AFGLLKEO_03213 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_03214 0.0 msbA2 3.6.3.44 V ABC transporter
AFGLLKEO_03215 3.3e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
AFGLLKEO_03216 9.6e-138 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AFGLLKEO_03217 3.4e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AFGLLKEO_03218 6e-117 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AFGLLKEO_03219 3e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
AFGLLKEO_03220 7e-237 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AFGLLKEO_03221 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AFGLLKEO_03222 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AFGLLKEO_03223 1.8e-138 yvpB NU protein conserved in bacteria
AFGLLKEO_03224 5.4e-84 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
AFGLLKEO_03225 1.7e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
AFGLLKEO_03226 1.2e-151 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AFGLLKEO_03227 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AFGLLKEO_03228 9.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AFGLLKEO_03229 1.2e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AFGLLKEO_03230 1.1e-133 yvoA K transcriptional
AFGLLKEO_03231 1.2e-105 yxaF K Transcriptional regulator
AFGLLKEO_03232 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
AFGLLKEO_03233 3.9e-41 yvlD S Membrane
AFGLLKEO_03234 9.6e-26 pspB KT PspC domain
AFGLLKEO_03235 3.2e-166 yvlB S Putative adhesin
AFGLLKEO_03236 6.1e-49 yvlA
AFGLLKEO_03237 3e-38 yvkN
AFGLLKEO_03238 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AFGLLKEO_03239 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AFGLLKEO_03240 7.6e-33 csbA S protein conserved in bacteria
AFGLLKEO_03241 0.0 yvkC 2.7.9.2 GT Phosphotransferase
AFGLLKEO_03242 2.4e-110 yvkB K Transcriptional regulator
AFGLLKEO_03243 3e-227 yvkA EGP Major facilitator Superfamily
AFGLLKEO_03244 5.2e-223 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFGLLKEO_03245 4.1e-56 swrA S Swarming motility protein
AFGLLKEO_03246 5e-257 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
AFGLLKEO_03247 8.8e-230 ywoF P Right handed beta helix region
AFGLLKEO_03248 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
AFGLLKEO_03249 1e-122 ftsE D cell division ATP-binding protein FtsE
AFGLLKEO_03250 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
AFGLLKEO_03251 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
AFGLLKEO_03252 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AFGLLKEO_03253 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AFGLLKEO_03254 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AFGLLKEO_03255 6.8e-68
AFGLLKEO_03256 5.3e-11 fliT S bacterial-type flagellum organization
AFGLLKEO_03257 3e-66 fliS N flagellar protein FliS
AFGLLKEO_03258 4.3e-262 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AFGLLKEO_03259 3.9e-116 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AFGLLKEO_03260 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AFGLLKEO_03261 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AFGLLKEO_03262 1.2e-81 yviE
AFGLLKEO_03263 6.1e-163 flgL N Belongs to the bacterial flagellin family
AFGLLKEO_03264 4.4e-275 flgK N flagellar hook-associated protein
AFGLLKEO_03265 8.9e-81 flgN NOU FlgN protein
AFGLLKEO_03266 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
AFGLLKEO_03267 1.4e-74 yvyF S flagellar protein
AFGLLKEO_03268 1.1e-78 comFC S Phosphoribosyl transferase domain
AFGLLKEO_03269 1.5e-43 comFB S Late competence development protein ComFB
AFGLLKEO_03270 8.1e-268 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AFGLLKEO_03271 1.4e-158 degV S protein conserved in bacteria
AFGLLKEO_03272 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFGLLKEO_03273 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
AFGLLKEO_03274 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
AFGLLKEO_03275 3e-173 yvhJ K Transcriptional regulator
AFGLLKEO_03276 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
AFGLLKEO_03277 1.2e-240 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
AFGLLKEO_03278 6.8e-144 tuaG GT2 M Glycosyltransferase like family 2
AFGLLKEO_03279 6.4e-117 tuaF M protein involved in exopolysaccharide biosynthesis
AFGLLKEO_03280 1.7e-260 tuaE M Teichuronic acid biosynthesis protein
AFGLLKEO_03281 7.8e-252 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFGLLKEO_03282 3.9e-226 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
AFGLLKEO_03283 9.3e-259 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFGLLKEO_03284 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
AFGLLKEO_03285 5.4e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
AFGLLKEO_03286 0.0 lytB 3.5.1.28 D Stage II sporulation protein
AFGLLKEO_03287 5.9e-49
AFGLLKEO_03288 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
AFGLLKEO_03289 6.7e-212 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AFGLLKEO_03290 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AFGLLKEO_03291 4e-284 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AFGLLKEO_03292 1.7e-151 tagG GM Transport permease protein
AFGLLKEO_03293 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AFGLLKEO_03294 8.6e-295 M Glycosyltransferase like family 2
AFGLLKEO_03295 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
AFGLLKEO_03296 1.5e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
AFGLLKEO_03297 3.7e-221 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AFGLLKEO_03298 1.7e-245 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AFGLLKEO_03299 2.5e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
AFGLLKEO_03300 9.3e-267 gerBA EG Spore germination protein
AFGLLKEO_03301 6.8e-201 gerBB E Spore germination protein
AFGLLKEO_03302 6.5e-215 gerAC S Spore germination protein
AFGLLKEO_03303 8.6e-270 GT2,GT4 J Glycosyl transferase family 2
AFGLLKEO_03304 3.7e-249 ywtG EGP Major facilitator Superfamily
AFGLLKEO_03305 3.8e-179 ywtF K Transcriptional regulator
AFGLLKEO_03306 4.5e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
AFGLLKEO_03307 2.9e-38 yttA 2.7.13.3 S Pfam Transposase IS66
AFGLLKEO_03308 5.2e-242 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
AFGLLKEO_03309 1.3e-20 ywtC
AFGLLKEO_03310 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
AFGLLKEO_03311 2.3e-70 pgsC S biosynthesis protein
AFGLLKEO_03312 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
AFGLLKEO_03313 1.7e-183 gerKA EG Spore germination protein
AFGLLKEO_03314 6.7e-193 gerKB E Spore germination protein
AFGLLKEO_03315 5.5e-206 gerKC S Spore germination B3/ GerAC like, C-terminal
AFGLLKEO_03316 1.8e-181 rbsR K transcriptional
AFGLLKEO_03317 6.1e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AFGLLKEO_03318 4.3e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
AFGLLKEO_03319 3.4e-280 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
AFGLLKEO_03320 2.9e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
AFGLLKEO_03321 5.2e-162 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
AFGLLKEO_03322 1.4e-90 batE T Sh3 type 3 domain protein
AFGLLKEO_03323 2.2e-96 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
AFGLLKEO_03324 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
AFGLLKEO_03325 2.4e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
AFGLLKEO_03326 9e-167 alsR K LysR substrate binding domain
AFGLLKEO_03327 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AFGLLKEO_03328 4.4e-126 ywrJ
AFGLLKEO_03329 4.4e-134 cotB
AFGLLKEO_03330 4.1e-214 cotH M Spore Coat
AFGLLKEO_03331 2e-09
AFGLLKEO_03332 2.5e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AFGLLKEO_03333 2e-307 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
AFGLLKEO_03334 1.1e-83 ywrC K Transcriptional regulator
AFGLLKEO_03335 8.3e-105 ywrB P Chromate transporter
AFGLLKEO_03336 2e-89 ywrA P COG2059 Chromate transport protein ChrA
AFGLLKEO_03337 1.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
AFGLLKEO_03338 1.6e-93
AFGLLKEO_03339 4.6e-48 S SMI1 / KNR4 family (SUKH-1)
AFGLLKEO_03340 3.8e-104 S Domain of unknown function (DUF1851)
AFGLLKEO_03341 3.4e-79 S LXG domain of WXG superfamily
AFGLLKEO_03342 6.3e-93
AFGLLKEO_03343 2e-49
AFGLLKEO_03344 0.0 ywqJ S Pre-toxin TG
AFGLLKEO_03345 4.3e-37 ywqI S Family of unknown function (DUF5344)
AFGLLKEO_03346 8.5e-22 S Domain of unknown function (DUF5082)
AFGLLKEO_03348 9.9e-154 ywqG S Domain of unknown function (DUF1963)
AFGLLKEO_03349 9.5e-250 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFGLLKEO_03350 1.7e-142 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
AFGLLKEO_03351 6.7e-122 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
AFGLLKEO_03352 5.2e-112 ywqC M biosynthesis protein
AFGLLKEO_03353 1.3e-14
AFGLLKEO_03354 2.2e-309 ywqB S SWIM zinc finger
AFGLLKEO_03355 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
AFGLLKEO_03356 2.5e-158 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
AFGLLKEO_03357 7.5e-138 glcR K DeoR C terminal sensor domain
AFGLLKEO_03358 7.5e-58 ssbB L Single-stranded DNA-binding protein
AFGLLKEO_03359 4e-62 ywpG
AFGLLKEO_03360 3.9e-69 ywpF S YwpF-like protein
AFGLLKEO_03361 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AFGLLKEO_03362 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AFGLLKEO_03363 1.3e-201 S aspartate phosphatase
AFGLLKEO_03364 6.1e-146 flhP N flagellar basal body
AFGLLKEO_03365 3.2e-128 flhO N flagellar basal body
AFGLLKEO_03366 2.7e-180 mbl D Rod shape-determining protein
AFGLLKEO_03367 1.8e-44 spoIIID K Stage III sporulation protein D
AFGLLKEO_03368 8.5e-72 ywoH K transcriptional
AFGLLKEO_03369 3.8e-213 ywoG EGP Major facilitator Superfamily
AFGLLKEO_03370 1.9e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
AFGLLKEO_03371 7.2e-245 ywoD EGP Major facilitator superfamily
AFGLLKEO_03372 5.7e-103 phzA Q Isochorismatase family
AFGLLKEO_03373 2.5e-228 amt P Ammonium transporter
AFGLLKEO_03374 2e-58 nrgB K Belongs to the P(II) protein family
AFGLLKEO_03375 2.2e-210 ftsW D Belongs to the SEDS family
AFGLLKEO_03376 3.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
AFGLLKEO_03377 1.7e-72 ywnJ S VanZ like family
AFGLLKEO_03378 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
AFGLLKEO_03379 4.9e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
AFGLLKEO_03380 1.2e-10 ywnC S Family of unknown function (DUF5362)
AFGLLKEO_03381 4.2e-69 ywnF S Family of unknown function (DUF5392)
AFGLLKEO_03382 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFGLLKEO_03383 4.4e-54 ywnC S Family of unknown function (DUF5362)
AFGLLKEO_03384 3.1e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
AFGLLKEO_03385 2.1e-67 ywnA K Transcriptional regulator
AFGLLKEO_03386 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
AFGLLKEO_03387 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
AFGLLKEO_03388 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
AFGLLKEO_03389 6.5e-11 csbD K CsbD-like
AFGLLKEO_03390 9.5e-83 ywmF S Peptidase M50
AFGLLKEO_03391 2.8e-93 S response regulator aspartate phosphatase
AFGLLKEO_03392 1.8e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AFGLLKEO_03393 2e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AFGLLKEO_03395 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
AFGLLKEO_03396 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
AFGLLKEO_03397 1.9e-189 spoIID D Stage II sporulation protein D
AFGLLKEO_03398 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFGLLKEO_03399 6.7e-136 ywmB S TATA-box binding
AFGLLKEO_03400 1.3e-32 ywzB S membrane
AFGLLKEO_03401 1.2e-90 ywmA
AFGLLKEO_03402 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AFGLLKEO_03403 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AFGLLKEO_03404 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AFGLLKEO_03405 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AFGLLKEO_03406 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFGLLKEO_03407 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AFGLLKEO_03408 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFGLLKEO_03409 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
AFGLLKEO_03410 2.1e-61 atpI S ATP synthase
AFGLLKEO_03411 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AFGLLKEO_03412 1.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AFGLLKEO_03413 5.9e-97 ywlG S Belongs to the UPF0340 family
AFGLLKEO_03414 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
AFGLLKEO_03415 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AFGLLKEO_03416 4.5e-92 mntP P Probably functions as a manganese efflux pump
AFGLLKEO_03417 3.2e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AFGLLKEO_03418 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
AFGLLKEO_03419 1.5e-121 spoIIR S stage II sporulation protein R
AFGLLKEO_03420 1e-60 ywlA S Uncharacterised protein family (UPF0715)
AFGLLKEO_03422 5.5e-158 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AFGLLKEO_03423 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AFGLLKEO_03424 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFGLLKEO_03425 6.7e-96 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
AFGLLKEO_03426 3.6e-158 ywkB S Membrane transport protein
AFGLLKEO_03427 0.0 sfcA 1.1.1.38 C malic enzyme
AFGLLKEO_03428 1.4e-104 tdk 2.7.1.21 F thymidine kinase
AFGLLKEO_03429 1.1e-32 rpmE J Binds the 23S rRNA
AFGLLKEO_03430 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AFGLLKEO_03431 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
AFGLLKEO_03432 5.1e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFGLLKEO_03433 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AFGLLKEO_03434 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
AFGLLKEO_03435 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
AFGLLKEO_03436 1.7e-93 ywjG S Domain of unknown function (DUF2529)
AFGLLKEO_03437 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AFGLLKEO_03438 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AFGLLKEO_03439 0.0 fadF C COG0247 Fe-S oxidoreductase
AFGLLKEO_03440 1.3e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
AFGLLKEO_03441 7.7e-185 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
AFGLLKEO_03442 2.4e-43 ywjC
AFGLLKEO_03443 0.0 ywjA V ABC transporter
AFGLLKEO_03444 9.6e-302 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFGLLKEO_03445 2.8e-106 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFGLLKEO_03446 2.4e-124 narI 1.7.5.1 C nitrate reductase, gamma
AFGLLKEO_03447 1.9e-98 narJ 1.7.5.1 C nitrate reductase
AFGLLKEO_03448 1.8e-294 narH 1.7.5.1 C Nitrate reductase, beta
AFGLLKEO_03449 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFGLLKEO_03450 2e-85 arfM T cyclic nucleotide binding
AFGLLKEO_03451 5.1e-141 ywiC S YwiC-like protein
AFGLLKEO_03452 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
AFGLLKEO_03453 5.8e-214 narK P COG2223 Nitrate nitrite transporter
AFGLLKEO_03454 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
AFGLLKEO_03455 1.2e-73 ywiB S protein conserved in bacteria
AFGLLKEO_03457 1.4e-232 ywhL CO amine dehydrogenase activity
AFGLLKEO_03458 1.3e-222 ywhK CO amine dehydrogenase activity
AFGLLKEO_03459 2.4e-76 S aspartate phosphatase
AFGLLKEO_03461 2.6e-29 ydcG K sequence-specific DNA binding
AFGLLKEO_03462 5e-33
AFGLLKEO_03463 2e-28 S Domain of unknown function (DUF4177)
AFGLLKEO_03465 3.6e-77 CP Membrane
AFGLLKEO_03468 5.4e-169 speB 3.5.3.11 E Belongs to the arginase family
AFGLLKEO_03469 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AFGLLKEO_03470 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFGLLKEO_03471 3.5e-84
AFGLLKEO_03472 1.4e-95 ywhD S YwhD family
AFGLLKEO_03473 1.1e-118 ywhC S Peptidase family M50
AFGLLKEO_03474 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
AFGLLKEO_03475 3.6e-70 ywhA K Transcriptional regulator
AFGLLKEO_03476 1.6e-247 yhdG_1 E C-terminus of AA_permease
AFGLLKEO_03477 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
AFGLLKEO_03478 7.9e-257 ywfO S COG1078 HD superfamily phosphohydrolases
AFGLLKEO_03479 6.9e-36 ywzC S Belongs to the UPF0741 family
AFGLLKEO_03480 3e-110 rsfA_1
AFGLLKEO_03481 7.4e-52 padR K PadR family transcriptional regulator
AFGLLKEO_03482 8.1e-94 S membrane
AFGLLKEO_03483 9.1e-167 V ABC transporter, ATP-binding protein
AFGLLKEO_03484 3.5e-169 yhcI S ABC transporter (permease)
AFGLLKEO_03487 1.2e-179
AFGLLKEO_03489 2.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
AFGLLKEO_03490 6e-163 cysL K Transcriptional regulator
AFGLLKEO_03491 7.9e-161 MA20_14895 S Conserved hypothetical protein 698
AFGLLKEO_03492 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
AFGLLKEO_03493 1.1e-146 ywfI C May function as heme-dependent peroxidase
AFGLLKEO_03494 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
AFGLLKEO_03495 2.1e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
AFGLLKEO_03496 1.2e-208 bacE EGP Major facilitator Superfamily
AFGLLKEO_03497 2e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
AFGLLKEO_03498 4.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFGLLKEO_03499 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
AFGLLKEO_03500 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
AFGLLKEO_03501 2.6e-225 ywfA EGP Major facilitator Superfamily
AFGLLKEO_03502 4.3e-209 tcaB EGP Major facilitator Superfamily
AFGLLKEO_03503 7.5e-261 lysP E amino acid
AFGLLKEO_03504 0.0 rocB E arginine degradation protein
AFGLLKEO_03505 5.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
AFGLLKEO_03506 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
AFGLLKEO_03507 1.5e-164 T PhoQ Sensor
AFGLLKEO_03508 3.5e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_03509 4.9e-45 S Putative adhesin
AFGLLKEO_03510 3.9e-84
AFGLLKEO_03511 2.9e-120 S ABC-2 family transporter protein
AFGLLKEO_03512 6.7e-173 bcrA5 V ABC transporter, ATP-binding protein
AFGLLKEO_03513 2.7e-87 spsL 5.1.3.13 M Spore Coat
AFGLLKEO_03514 1.3e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AFGLLKEO_03515 9.3e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AFGLLKEO_03516 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AFGLLKEO_03517 2.9e-190 spsG M Spore Coat
AFGLLKEO_03518 2.7e-137 spsF M Spore Coat
AFGLLKEO_03519 3.4e-216 spsE 2.5.1.56 M acid synthase
AFGLLKEO_03520 2.4e-161 spsD 2.3.1.210 K Spore Coat
AFGLLKEO_03521 5.1e-223 spsC E Belongs to the DegT DnrJ EryC1 family
AFGLLKEO_03522 1.2e-277 spsB M Capsule polysaccharide biosynthesis protein
AFGLLKEO_03523 2.6e-143 spsA M Spore Coat
AFGLLKEO_03524 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
AFGLLKEO_03525 1.4e-46 ywdK S small membrane protein
AFGLLKEO_03526 5.2e-232 ywdJ F Xanthine uracil
AFGLLKEO_03527 7.3e-41 ywdI S Family of unknown function (DUF5327)
AFGLLKEO_03528 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AFGLLKEO_03529 5.4e-155 ywdF GT2,GT4 S Glycosyltransferase like family 2
AFGLLKEO_03531 5.3e-89 ywdD
AFGLLKEO_03532 6.3e-57 pex K Transcriptional regulator PadR-like family
AFGLLKEO_03533 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AFGLLKEO_03534 9.7e-20 ywdA
AFGLLKEO_03535 1.2e-290 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
AFGLLKEO_03536 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFGLLKEO_03537 1.3e-151 sacT K transcriptional antiterminator
AFGLLKEO_03539 0.0 vpr O Belongs to the peptidase S8 family
AFGLLKEO_03540 3.9e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFGLLKEO_03541 2.2e-54 L COG2963 Transposase and inactivated derivatives
AFGLLKEO_03542 9.5e-135 L Molecular Function DNA binding, Biological Process DNA recombination
AFGLLKEO_03543 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
AFGLLKEO_03544 9.8e-214 rodA D Belongs to the SEDS family
AFGLLKEO_03545 1e-82 ysnE K acetyltransferase
AFGLLKEO_03546 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
AFGLLKEO_03547 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
AFGLLKEO_03548 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
AFGLLKEO_03549 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AFGLLKEO_03550 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
AFGLLKEO_03551 8.4e-27 ywzA S membrane
AFGLLKEO_03552 4.3e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
AFGLLKEO_03553 5.7e-230 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AFGLLKEO_03554 1.9e-63 gtcA S GtrA-like protein
AFGLLKEO_03555 8.7e-113 ywcC K Bacterial regulatory proteins, tetR family
AFGLLKEO_03557 1.9e-129 H Methionine biosynthesis protein MetW
AFGLLKEO_03558 2.6e-134 S Streptomycin biosynthesis protein StrF
AFGLLKEO_03559 5.5e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
AFGLLKEO_03560 1.1e-244 ywbN P Dyp-type peroxidase family protein
AFGLLKEO_03561 9.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
AFGLLKEO_03562 6e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AFGLLKEO_03563 8.2e-152 ywbI K Transcriptional regulator
AFGLLKEO_03564 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
AFGLLKEO_03565 1.5e-110 ywbG M effector of murein hydrolase
AFGLLKEO_03566 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
AFGLLKEO_03567 2.2e-142 mta K transcriptional
AFGLLKEO_03568 1.2e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
AFGLLKEO_03569 5.5e-225 ywbD 2.1.1.191 J Methyltransferase
AFGLLKEO_03570 9e-68 ywbC 4.4.1.5 E glyoxalase
AFGLLKEO_03571 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFGLLKEO_03572 7e-269 epr 3.4.21.62 O Belongs to the peptidase S8 family
AFGLLKEO_03573 5.2e-164 gspA M General stress
AFGLLKEO_03574 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
AFGLLKEO_03575 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
AFGLLKEO_03576 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
AFGLLKEO_03577 4.2e-294 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_03578 3.7e-229 dltB M membrane protein involved in D-alanine export
AFGLLKEO_03579 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFGLLKEO_03580 3.7e-229 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AFGLLKEO_03581 4e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
AFGLLKEO_03582 9.2e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
AFGLLKEO_03583 7.8e-52 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
AFGLLKEO_03584 2.6e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFGLLKEO_03585 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
AFGLLKEO_03586 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
AFGLLKEO_03587 1.1e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
AFGLLKEO_03588 4.3e-173 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFGLLKEO_03589 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFGLLKEO_03590 3e-167 cbrA3 P Periplasmic binding protein
AFGLLKEO_03591 3.7e-60 arsR K transcriptional
AFGLLKEO_03592 1.4e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AFGLLKEO_03593 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
AFGLLKEO_03594 1.4e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
AFGLLKEO_03595 3.7e-230 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFGLLKEO_03596 7.1e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFGLLKEO_03597 4.2e-169 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
AFGLLKEO_03598 8.4e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
AFGLLKEO_03599 4.4e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
AFGLLKEO_03600 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
AFGLLKEO_03601 6.5e-195 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
AFGLLKEO_03602 4.2e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
AFGLLKEO_03603 7e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AFGLLKEO_03604 2.2e-294 cydD V ATP-binding protein
AFGLLKEO_03605 0.0 cydD V ATP-binding
AFGLLKEO_03606 4.2e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
AFGLLKEO_03607 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
AFGLLKEO_03608 1.5e-215 cimH C COG3493 Na citrate symporter
AFGLLKEO_03609 7.1e-158 yxkH G Polysaccharide deacetylase
AFGLLKEO_03610 2.4e-206 msmK P Belongs to the ABC transporter superfamily
AFGLLKEO_03611 6.5e-170 lrp QT PucR C-terminal helix-turn-helix domain
AFGLLKEO_03612 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFGLLKEO_03613 3.8e-87 yxkC S Domain of unknown function (DUF4352)
AFGLLKEO_03614 2.1e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AFGLLKEO_03615 6.5e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AFGLLKEO_03618 1.8e-86 yxjI S LURP-one-related
AFGLLKEO_03619 1.5e-219 yxjG 2.1.1.14 E Methionine synthase
AFGLLKEO_03620 5.6e-166 rlmA 2.1.1.187 Q Methyltransferase domain
AFGLLKEO_03621 3.5e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AFGLLKEO_03622 2.7e-75 T Domain of unknown function (DUF4163)
AFGLLKEO_03623 1.6e-51 yxiS
AFGLLKEO_03624 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
AFGLLKEO_03625 5.6e-223 citH C Citrate transporter
AFGLLKEO_03626 5e-144 exoK GH16 M licheninase activity
AFGLLKEO_03627 1.8e-150 licT K transcriptional antiterminator
AFGLLKEO_03628 2.9e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
AFGLLKEO_03629 1.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
AFGLLKEO_03632 2.9e-63 S SMI1-KNR4 cell-wall
AFGLLKEO_03633 9.1e-91 yxiI S Protein of unknown function (DUF2716)
AFGLLKEO_03635 3.1e-74 yxiG
AFGLLKEO_03636 7.1e-71 yxxG
AFGLLKEO_03638 3.7e-204 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
AFGLLKEO_03639 3.2e-148 yxxF EG EamA-like transporter family
AFGLLKEO_03640 9.8e-74 yxiE T Belongs to the universal stress protein A family
AFGLLKEO_03641 6.4e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFGLLKEO_03642 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFGLLKEO_03643 0.0 L HKD family nuclease
AFGLLKEO_03644 6.5e-66 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
AFGLLKEO_03645 1.5e-282 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
AFGLLKEO_03646 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
AFGLLKEO_03647 3.5e-288 hutH 4.3.1.3 E Histidine ammonia-lyase
AFGLLKEO_03648 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AFGLLKEO_03649 6.5e-240 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
AFGLLKEO_03650 3.1e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
AFGLLKEO_03651 2e-253 lysP E amino acid
AFGLLKEO_03652 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
AFGLLKEO_03653 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AFGLLKEO_03654 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AFGLLKEO_03655 2.3e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
AFGLLKEO_03656 6.2e-151 yidA S hydrolases of the HAD superfamily
AFGLLKEO_03659 6.4e-13 yxeE
AFGLLKEO_03660 8.4e-23 yxeD
AFGLLKEO_03661 1.3e-14
AFGLLKEO_03662 7.5e-11
AFGLLKEO_03663 4.4e-180 fhuD P Periplasmic binding protein
AFGLLKEO_03664 2.2e-54 L COG2963 Transposase and inactivated derivatives
AFGLLKEO_03665 7.3e-135 L Molecular Function DNA binding, Biological Process DNA recombination
AFGLLKEO_03666 2.6e-58 yxeA S Protein of unknown function (DUF1093)
AFGLLKEO_03667 0.0 yxdM V ABC transporter (permease)
AFGLLKEO_03668 5.5e-141 yxdL V ABC transporter, ATP-binding protein
AFGLLKEO_03669 1e-176 T PhoQ Sensor
AFGLLKEO_03670 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_03671 8.4e-276 T Histidine kinase
AFGLLKEO_03672 2.4e-138 T Transcriptional regulator
AFGLLKEO_03673 1.4e-164 bcrA V ABC transporter, ATP-binding protein
AFGLLKEO_03674 1e-131 S permease
AFGLLKEO_03675 9.3e-130 S ABC-2 family transporter protein
AFGLLKEO_03676 4.9e-162 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
AFGLLKEO_03677 1.3e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
AFGLLKEO_03678 1.1e-166 iolH G Xylose isomerase-like TIM barrel
AFGLLKEO_03679 3.3e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
AFGLLKEO_03680 2.4e-234 iolF EGP Major facilitator Superfamily
AFGLLKEO_03681 1e-178 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
AFGLLKEO_03682 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
AFGLLKEO_03683 6.8e-184 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
AFGLLKEO_03684 1.5e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
AFGLLKEO_03685 1.2e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFGLLKEO_03686 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
AFGLLKEO_03687 4.9e-176 iolS C Aldo keto reductase
AFGLLKEO_03688 6.7e-246 csbC EGP Major facilitator Superfamily
AFGLLKEO_03689 0.0 htpG O Molecular chaperone. Has ATPase activity
AFGLLKEO_03690 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
AFGLLKEO_03691 2.5e-104 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFGLLKEO_03692 1.7e-202 desK 2.7.13.3 T Histidine kinase
AFGLLKEO_03693 3.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
AFGLLKEO_03694 4.3e-222 yxbF K Bacterial regulatory proteins, tetR family
AFGLLKEO_03695 3.9e-251 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
AFGLLKEO_03696 3.3e-143 S PQQ-like domain
AFGLLKEO_03697 4.1e-66 S Family of unknown function (DUF5391)
AFGLLKEO_03698 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
AFGLLKEO_03699 6.7e-207 EGP Major facilitator Superfamily
AFGLLKEO_03700 5.3e-75 yxaI S membrane protein domain
AFGLLKEO_03701 5.1e-130 E Ring-cleavage extradiol dioxygenase
AFGLLKEO_03702 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
AFGLLKEO_03703 2.3e-287 ahpF O Alkyl hydroperoxide reductase
AFGLLKEO_03704 5.4e-231 XK27_00240 S Fic/DOC family
AFGLLKEO_03705 6.5e-246 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
AFGLLKEO_03706 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
AFGLLKEO_03707 3e-86 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
AFGLLKEO_03708 5.8e-160 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
AFGLLKEO_03709 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
AFGLLKEO_03710 2.3e-97 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
AFGLLKEO_03711 1.3e-193 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AFGLLKEO_03712 1.3e-185 S Fusaric acid resistance protein-like
AFGLLKEO_03716 9.4e-286 L ATPase involved in DNA repair
AFGLLKEO_03717 2.8e-08
AFGLLKEO_03718 4.6e-238 T Putative serine esterase (DUF676)
AFGLLKEO_03719 9.8e-190
AFGLLKEO_03720 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AFGLLKEO_03721 7.9e-08 S YyzF-like protein
AFGLLKEO_03723 3.5e-224 yycP
AFGLLKEO_03724 1.7e-134 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AFGLLKEO_03725 1.4e-186 C oxidoreductases (related to aryl-alcohol dehydrogenases)
AFGLLKEO_03726 1.5e-88 yycN 2.3.1.128 K Acetyltransferase
AFGLLKEO_03728 8.6e-204 S Histidine kinase
AFGLLKEO_03729 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
AFGLLKEO_03730 6.9e-259 rocE E amino acid
AFGLLKEO_03731 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
AFGLLKEO_03732 3.4e-261 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
AFGLLKEO_03733 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
AFGLLKEO_03734 7.9e-307 S ABC transporter
AFGLLKEO_03735 2.6e-198 S Major Facilitator Superfamily
AFGLLKEO_03736 4.7e-265
AFGLLKEO_03737 9.5e-194 2.7.7.73, 2.7.7.80 H ThiF family
AFGLLKEO_03738 1.8e-259 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
AFGLLKEO_03739 3.2e-11 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_03740 8.3e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFGLLKEO_03741 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
AFGLLKEO_03742 8.9e-153 yycI S protein conserved in bacteria
AFGLLKEO_03743 2.5e-261 yycH S protein conserved in bacteria
AFGLLKEO_03744 0.0 vicK 2.7.13.3 T Histidine kinase
AFGLLKEO_03745 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFGLLKEO_03750 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AFGLLKEO_03751 4.8e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFGLLKEO_03752 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AFGLLKEO_03753 1.6e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
AFGLLKEO_03755 3.5e-17 yycC K YycC-like protein
AFGLLKEO_03756 2.9e-41 M 4-amino-4-deoxy-L-arabinose transferase activity
AFGLLKEO_03757 3e-248 M Glycosyltransferase Family 4
AFGLLKEO_03758 3.5e-207 S Ecdysteroid kinase
AFGLLKEO_03759 7.5e-238 S Carbamoyl-phosphate synthase L chain, ATP binding domain
AFGLLKEO_03760 5.4e-253 M Glycosyltransferase Family 4
AFGLLKEO_03761 9.8e-123 S GlcNAc-PI de-N-acetylase
AFGLLKEO_03762 1.8e-127 KLT COG0515 Serine threonine protein kinase
AFGLLKEO_03763 4.9e-73 rplI J binds to the 23S rRNA
AFGLLKEO_03764 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AFGLLKEO_03765 2.9e-160 yybS S membrane
AFGLLKEO_03767 6e-85 cotF M Spore coat protein
AFGLLKEO_03768 2.8e-66 ydeP3 K Transcriptional regulator
AFGLLKEO_03769 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
AFGLLKEO_03770 1.4e-156 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AFGLLKEO_03771 7e-275 sacB 2.4.1.10 GH68 M levansucrase activity
AFGLLKEO_03772 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
AFGLLKEO_03773 4.8e-117 K FCD domain
AFGLLKEO_03774 1.3e-77 dinB S PFAM DinB family protein
AFGLLKEO_03775 1.2e-163 G Major Facilitator Superfamily
AFGLLKEO_03776 1.7e-17 G Major Facilitator Superfamily
AFGLLKEO_03777 3.4e-163 yfiE K LysR substrate binding domain
AFGLLKEO_03778 1.1e-100 E LysE type translocator
AFGLLKEO_03779 3e-218 ynfM EGP Major facilitator Superfamily
AFGLLKEO_03780 3.3e-166 gltC K Transcriptional regulator
AFGLLKEO_03781 3.4e-56 ypaA S Protein of unknown function (DUF1304)
AFGLLKEO_03782 5.6e-115 drgA C nitroreductase
AFGLLKEO_03783 1.1e-69 ydgJ K Winged helix DNA-binding domain
AFGLLKEO_03784 3.8e-154 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
AFGLLKEO_03785 2.5e-77 yybA 2.3.1.57 K transcriptional
AFGLLKEO_03786 1.8e-77 yjcF S Acetyltransferase (GNAT) domain
AFGLLKEO_03787 2.3e-164 eaeH M Domain of Unknown Function (DUF1259)
AFGLLKEO_03788 9.4e-68 4.1.1.44 S Carboxymuconolactone decarboxylase family
AFGLLKEO_03789 4.5e-166 K Transcriptional regulator
AFGLLKEO_03790 3.6e-143 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
AFGLLKEO_03791 4.4e-100
AFGLLKEO_03792 1.5e-27 yyaL O Highly conserved protein containing a thioredoxin domain
AFGLLKEO_03793 4e-81
AFGLLKEO_03794 1.3e-69 ynaF
AFGLLKEO_03796 1.1e-250 KLT Protein tyrosine kinase
AFGLLKEO_03797 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
AFGLLKEO_03798 1.3e-165 yyaK S CAAX protease self-immunity
AFGLLKEO_03799 2.1e-249 ydjK G Sugar (and other) transporter
AFGLLKEO_03800 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFGLLKEO_03801 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
AFGLLKEO_03802 5.1e-147 xth 3.1.11.2 L exodeoxyribonuclease III
AFGLLKEO_03803 4.3e-103 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AFGLLKEO_03804 4.9e-110 adaA 3.2.2.21 K Transcriptional regulator
AFGLLKEO_03805 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AFGLLKEO_03806 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AFGLLKEO_03807 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
AFGLLKEO_03808 1.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AFGLLKEO_03809 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFGLLKEO_03810 7.8e-34 yyzM S protein conserved in bacteria
AFGLLKEO_03811 2.4e-176 yyaD S Membrane
AFGLLKEO_03812 1.8e-87 4.2.1.103 K FR47-like protein
AFGLLKEO_03813 6.2e-111 yyaC S Sporulation protein YyaC
AFGLLKEO_03814 1.6e-149 spo0J K Belongs to the ParB family
AFGLLKEO_03815 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
AFGLLKEO_03816 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
AFGLLKEO_03817 1.3e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
AFGLLKEO_03818 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AFGLLKEO_03819 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AFGLLKEO_03820 4.5e-112 jag S single-stranded nucleic acid binding R3H
AFGLLKEO_03821 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFGLLKEO_03822 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)