ORF_ID e_value Gene_name EC_number CAZy COGs Description
LAPPPKNL_00001 7.6e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LAPPPKNL_00002 2.5e-225 mtnE 2.6.1.83 E Aminotransferase
LAPPPKNL_00003 7.5e-146 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
LAPPPKNL_00004 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LAPPPKNL_00005 5.3e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LAPPPKNL_00006 3.1e-161 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LAPPPKNL_00007 9.2e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LAPPPKNL_00008 1.2e-47 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
LAPPPKNL_00009 4.1e-53 KT PspC domain protein
LAPPPKNL_00010 1.3e-201 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LAPPPKNL_00011 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LAPPPKNL_00012 6.5e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LAPPPKNL_00013 4.7e-128 comFC S Competence protein
LAPPPKNL_00014 6.3e-254 comFA L Helicase C-terminal domain protein
LAPPPKNL_00015 1.1e-113 yvyE 3.4.13.9 S YigZ family
LAPPPKNL_00016 6.4e-38
LAPPPKNL_00017 0.0 ydaO E amino acid
LAPPPKNL_00018 1.4e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LAPPPKNL_00019 4.3e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LAPPPKNL_00020 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LAPPPKNL_00021 0.0 uup S ABC transporter, ATP-binding protein
LAPPPKNL_00022 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LAPPPKNL_00023 3.6e-89 bioY S BioY family
LAPPPKNL_00024 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LAPPPKNL_00025 1e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
LAPPPKNL_00026 1.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LAPPPKNL_00027 7.1e-264 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
LAPPPKNL_00028 1.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LAPPPKNL_00029 1.6e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LAPPPKNL_00030 6e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LAPPPKNL_00031 2.7e-129 IQ reductase
LAPPPKNL_00032 1.1e-172 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LAPPPKNL_00033 4.2e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAPPPKNL_00034 1.8e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LAPPPKNL_00035 2.3e-75 marR K Transcriptional regulator, MarR family
LAPPPKNL_00036 2.7e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LAPPPKNL_00038 1.2e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LAPPPKNL_00039 1.3e-110 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
LAPPPKNL_00040 1.1e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
LAPPPKNL_00041 7.6e-216 arcT 2.6.1.1 E Aminotransferase
LAPPPKNL_00042 2.7e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
LAPPPKNL_00043 1.2e-258 E Arginine ornithine antiporter
LAPPPKNL_00044 8.2e-240 arcA 3.5.3.6 E Arginine
LAPPPKNL_00045 1.4e-167 arcC 2.7.2.2 E Belongs to the carbamate kinase family
LAPPPKNL_00046 6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LAPPPKNL_00047 8.8e-148 KT YcbB domain
LAPPPKNL_00048 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LAPPPKNL_00049 6.7e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
LAPPPKNL_00050 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LAPPPKNL_00051 4.8e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
LAPPPKNL_00052 3.3e-146 fat 3.1.2.21 I Acyl-ACP thioesterase
LAPPPKNL_00053 2.7e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LAPPPKNL_00054 1.5e-55 yabA L Involved in initiation control of chromosome replication
LAPPPKNL_00055 1.4e-192 holB 2.7.7.7 L DNA polymerase III
LAPPPKNL_00056 4e-53 yaaQ S Cyclic-di-AMP receptor
LAPPPKNL_00057 6e-117 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LAPPPKNL_00058 2.4e-21 S Protein of unknown function (DUF2508)
LAPPPKNL_00059 3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LAPPPKNL_00060 4.9e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LAPPPKNL_00061 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LAPPPKNL_00063 6.3e-80 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LAPPPKNL_00064 2e-35 nrdH O Glutaredoxin
LAPPPKNL_00065 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LAPPPKNL_00066 8.6e-195 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LAPPPKNL_00067 4.1e-248 brnQ U Component of the transport system for branched-chain amino acids
LAPPPKNL_00068 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LAPPPKNL_00069 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LAPPPKNL_00070 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LAPPPKNL_00071 7.7e-175 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
LAPPPKNL_00072 1.1e-272 cydA 1.10.3.14 C ubiquinol oxidase
LAPPPKNL_00073 4.6e-53 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LAPPPKNL_00074 8.4e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LAPPPKNL_00075 4.6e-244 steT E amino acid
LAPPPKNL_00076 7.4e-121 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LAPPPKNL_00077 2.2e-51 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LAPPPKNL_00078 4.5e-97 nusG K Participates in transcription elongation, termination and antitermination
LAPPPKNL_00079 6.9e-23 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LAPPPKNL_00080 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LAPPPKNL_00081 1.1e-104 sigH K Belongs to the sigma-70 factor family
LAPPPKNL_00082 5.2e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LAPPPKNL_00083 5.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LAPPPKNL_00084 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LAPPPKNL_00085 7.8e-100 ywlG S Belongs to the UPF0340 family
LAPPPKNL_00086 6.2e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LAPPPKNL_00087 9.4e-206 yacL S domain protein
LAPPPKNL_00088 5.6e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LAPPPKNL_00089 1.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
LAPPPKNL_00090 4.2e-55 HA62_12640 S GCN5-related N-acetyl-transferase
LAPPPKNL_00091 6.7e-122 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LAPPPKNL_00092 4e-94 maa 2.3.1.18, 2.3.1.79 S Transferase hexapeptide repeat
LAPPPKNL_00093 8.9e-264 pepC 3.4.22.40 E Peptidase C1-like family
LAPPPKNL_00094 1.5e-166 I alpha/beta hydrolase fold
LAPPPKNL_00095 1.4e-127 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LAPPPKNL_00096 2.3e-168 mleP2 S Sodium Bile acid symporter family
LAPPPKNL_00097 2e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
LAPPPKNL_00098 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
LAPPPKNL_00099 8.1e-84 ydcK S Belongs to the SprT family
LAPPPKNL_00100 0.0 yhgF K Tex-like protein N-terminal domain protein
LAPPPKNL_00101 8.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LAPPPKNL_00102 5e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LAPPPKNL_00103 1.4e-127 gntR1 K UbiC transcription regulator-associated domain protein
LAPPPKNL_00104 4.3e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LAPPPKNL_00105 9.6e-115
LAPPPKNL_00107 2.8e-126 yjjH S Calcineurin-like phosphoesterase
LAPPPKNL_00108 6.9e-257 dtpT U amino acid peptide transporter
LAPPPKNL_00109 2.8e-169 D nuclear chromosome segregation
LAPPPKNL_00110 4.3e-144 L transposase, IS605 OrfB family
LAPPPKNL_00111 8.6e-276 lacS G Transporter
LAPPPKNL_00112 0.0 rafA 3.2.1.22 G alpha-galactosidase
LAPPPKNL_00113 1.6e-180 galR K Transcriptional regulator
LAPPPKNL_00114 2.4e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LAPPPKNL_00115 1e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LAPPPKNL_00116 4.2e-183 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
LAPPPKNL_00117 3.5e-143 ptp3 3.1.3.48 T Tyrosine phosphatase family
LAPPPKNL_00118 2.7e-96 yxkA S Phosphatidylethanolamine-binding protein
LAPPPKNL_00119 6.9e-36
LAPPPKNL_00120 6.6e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LAPPPKNL_00121 7.4e-121 tcyB U Binding-protein-dependent transport system inner membrane component
LAPPPKNL_00122 1.7e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LAPPPKNL_00123 2e-52
LAPPPKNL_00124 1.4e-170 MA20_03535 1.1.1.399, 1.1.1.95 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAPPPKNL_00125 6.4e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LAPPPKNL_00126 6.9e-147 pnuC H nicotinamide mononucleotide transporter
LAPPPKNL_00127 2e-91 ymdB S Macro domain protein
LAPPPKNL_00128 0.0 pepO 3.4.24.71 O Peptidase family M13
LAPPPKNL_00129 1.8e-229 pbuG S permease
LAPPPKNL_00130 2.1e-45
LAPPPKNL_00131 7.6e-214 S Putative metallopeptidase domain
LAPPPKNL_00132 3.6e-205 3.1.3.1 S associated with various cellular activities
LAPPPKNL_00133 7.2e-115 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LAPPPKNL_00134 6.8e-65 yeaO S Protein of unknown function, DUF488
LAPPPKNL_00136 4.8e-125 yrkL S Flavodoxin-like fold
LAPPPKNL_00137 7.4e-55
LAPPPKNL_00138 2.2e-108 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
LAPPPKNL_00139 1e-96 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LAPPPKNL_00140 3.2e-102
LAPPPKNL_00141 9.5e-26
LAPPPKNL_00142 2.9e-168 scrR K Transcriptional regulator, LacI family
LAPPPKNL_00143 3.5e-174 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LAPPPKNL_00144 2.6e-46 czrA K Transcriptional regulator, ArsR family
LAPPPKNL_00145 1.8e-75 argR K Regulates arginine biosynthesis genes
LAPPPKNL_00146 5.5e-124 devA 3.6.3.25 V ABC transporter, ATP-binding protein
LAPPPKNL_00147 1.3e-158 hrtB V ABC transporter permease
LAPPPKNL_00148 8.2e-108 ygfC K Bacterial regulatory proteins, tetR family
LAPPPKNL_00149 9.3e-189 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
LAPPPKNL_00150 4.2e-281 mntH P H( )-stimulated, divalent metal cation uptake system
LAPPPKNL_00151 6.5e-22
LAPPPKNL_00152 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LAPPPKNL_00153 1.8e-70 L nuclease
LAPPPKNL_00154 5.8e-163 F DNA/RNA non-specific endonuclease
LAPPPKNL_00155 4.9e-13
LAPPPKNL_00157 1.2e-36 rusA L Endodeoxyribonuclease RusA
LAPPPKNL_00160 5.1e-44 dnaC 3.4.21.53 L IstB-like ATP binding protein
LAPPPKNL_00161 2.6e-144 arsB 1.20.4.1 P Sodium Bile acid symporter family
LAPPPKNL_00162 3.8e-56 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
LAPPPKNL_00163 9.8e-77
LAPPPKNL_00164 1.8e-38 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LAPPPKNL_00165 3e-102 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
LAPPPKNL_00166 6.2e-57 S Single-strand binding protein family
LAPPPKNL_00167 9.9e-114 S PDDEXK-like domain of unknown function (DUF3799)
LAPPPKNL_00168 8.2e-216 S response to antibiotic
LAPPPKNL_00169 1.1e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LAPPPKNL_00170 1.7e-151 glcU U sugar transport
LAPPPKNL_00171 1.5e-251 yclK 2.7.13.3 T Histidine kinase
LAPPPKNL_00172 9.7e-132 K response regulator
LAPPPKNL_00174 2.7e-27 S Domain of unknown function (DUF956)
LAPPPKNL_00175 3e-170 manN G system, mannose fructose sorbose family IID component
LAPPPKNL_00176 2.7e-122 manY G PTS system
LAPPPKNL_00177 4.5e-180 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
LAPPPKNL_00178 2.3e-181 yfeX P Peroxidase
LAPPPKNL_00179 2.5e-89 racA K Domain of unknown function (DUF1836)
LAPPPKNL_00180 1.1e-147 yitS S EDD domain protein, DegV family
LAPPPKNL_00181 3.8e-131 manA 5.3.1.8 G mannose-6-phosphate isomerase
LAPPPKNL_00182 2.8e-168 K LysR substrate binding domain
LAPPPKNL_00183 1.2e-156 MA20_14895 S Conserved hypothetical protein 698
LAPPPKNL_00184 2.4e-75 lytE M Lysin motif
LAPPPKNL_00185 4e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
LAPPPKNL_00186 7.1e-211 oatA I Acyltransferase
LAPPPKNL_00187 3.3e-52
LAPPPKNL_00188 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LAPPPKNL_00189 6.1e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LAPPPKNL_00190 9.1e-116 ybbR S YbbR-like protein
LAPPPKNL_00191 7.8e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LAPPPKNL_00192 5.7e-166 murB 1.3.1.98 M Cell wall formation
LAPPPKNL_00193 1.3e-101 dnaQ 2.7.7.7 L DNA polymerase III
LAPPPKNL_00194 7.3e-89 K Acetyltransferase (GNAT) domain
LAPPPKNL_00195 1.1e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
LAPPPKNL_00196 2.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LAPPPKNL_00197 4e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LAPPPKNL_00198 2.1e-108 yxjI
LAPPPKNL_00199 2.9e-84 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LAPPPKNL_00200 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LAPPPKNL_00201 4.5e-33 secG U Preprotein translocase
LAPPPKNL_00202 1.9e-289 clcA P chloride
LAPPPKNL_00203 1.5e-253 yifK E Amino acid permease
LAPPPKNL_00204 1e-248 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LAPPPKNL_00205 3.1e-144 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LAPPPKNL_00206 6.6e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LAPPPKNL_00207 3.8e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LAPPPKNL_00208 1e-15
LAPPPKNL_00209 1.4e-51 S Core-2/I-Branching enzyme
LAPPPKNL_00210 1.1e-195 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
LAPPPKNL_00211 1.6e-54
LAPPPKNL_00212 9.4e-33 kcsA P Ion transport protein
LAPPPKNL_00213 2.5e-75 L PFAM transposase, IS4 family protein
LAPPPKNL_00214 3.3e-138 ybeC E amino acid
LAPPPKNL_00215 7.3e-46
LAPPPKNL_00216 2.9e-62 K helix_turn_helix multiple antibiotic resistance protein
LAPPPKNL_00217 6.2e-134 ybeC E amino acid
LAPPPKNL_00218 1.3e-125 tnp L DDE domain
LAPPPKNL_00219 2.3e-150 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LAPPPKNL_00220 4.2e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LAPPPKNL_00221 2.9e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LAPPPKNL_00222 1.3e-176 2.4.2.29 F queuine tRNA-ribosyltransferase activity
LAPPPKNL_00223 5.5e-42 yajC U Preprotein translocase
LAPPPKNL_00224 3.4e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
LAPPPKNL_00225 8.4e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LAPPPKNL_00226 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LAPPPKNL_00227 1.2e-42 yrzL S Belongs to the UPF0297 family
LAPPPKNL_00228 9.6e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LAPPPKNL_00229 5.7e-33 yrzB S Belongs to the UPF0473 family
LAPPPKNL_00230 1.6e-163 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LAPPPKNL_00231 4.7e-91 cvpA S Colicin V production protein
LAPPPKNL_00232 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LAPPPKNL_00233 1e-53 trxA O Belongs to the thioredoxin family
LAPPPKNL_00234 3.5e-225 clcA_2 P Chloride transporter, ClC family
LAPPPKNL_00235 7.2e-95 yslB S Protein of unknown function (DUF2507)
LAPPPKNL_00236 1.2e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LAPPPKNL_00237 3.6e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LAPPPKNL_00238 1.4e-95 S Phosphoesterase
LAPPPKNL_00239 1.7e-151 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
LAPPPKNL_00240 4e-156 ykuT M mechanosensitive ion channel
LAPPPKNL_00241 9.2e-26 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LAPPPKNL_00242 4.9e-70
LAPPPKNL_00243 4.1e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LAPPPKNL_00244 2.2e-185 ccpA K catabolite control protein A
LAPPPKNL_00245 3.6e-85
LAPPPKNL_00246 3.7e-134 yebC K Transcriptional regulatory protein
LAPPPKNL_00247 4.6e-82 mltD CBM50 M PFAM NLP P60 protein
LAPPPKNL_00248 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
LAPPPKNL_00249 8.8e-136 comGA NU Type II IV secretion system protein
LAPPPKNL_00250 1.2e-32 comGA NU Type II IV secretion system protein
LAPPPKNL_00251 2.1e-159 comGB NU type II secretion system
LAPPPKNL_00252 1.1e-47 comGC U competence protein ComGC
LAPPPKNL_00253 2.3e-15 NU general secretion pathway protein
LAPPPKNL_00255 3.8e-14
LAPPPKNL_00257 4.6e-160 ytxK 2.1.1.72 L N-6 DNA Methylase
LAPPPKNL_00258 9.5e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LAPPPKNL_00259 5.3e-110 S Calcineurin-like phosphoesterase
LAPPPKNL_00260 1.2e-97 yutD S Protein of unknown function (DUF1027)
LAPPPKNL_00261 6.6e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LAPPPKNL_00262 9.8e-25 S Protein of unknown function (DUF1461)
LAPPPKNL_00263 3.5e-104 dedA S SNARE-like domain protein
LAPPPKNL_00265 6.4e-41 L Transposase, IS116 IS110 IS902 family
LAPPPKNL_00268 8.4e-142 pgi 5.3.1.9 G Belongs to the GPI family
LAPPPKNL_00269 1.2e-74 L Transposase
LAPPPKNL_00270 3e-184 fruR3 K Transcriptional regulator, LacI family
LAPPPKNL_00271 1.1e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
LAPPPKNL_00272 2.6e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LAPPPKNL_00273 3e-56 trxA1 O Belongs to the thioredoxin family
LAPPPKNL_00274 2.6e-141 terC P membrane
LAPPPKNL_00275 1.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LAPPPKNL_00276 9.7e-169 corA P CorA-like Mg2+ transporter protein
LAPPPKNL_00277 2.1e-228 pbuX F xanthine permease
LAPPPKNL_00278 1.9e-150 qorB 1.6.5.2 GM NmrA-like family
LAPPPKNL_00279 2.5e-126 pgm3 G phosphoglycerate mutase family
LAPPPKNL_00280 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LAPPPKNL_00281 2e-85
LAPPPKNL_00282 5.7e-107 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
LAPPPKNL_00283 1.2e-100 dps P Belongs to the Dps family
LAPPPKNL_00284 8.7e-34 copZ P Heavy-metal-associated domain
LAPPPKNL_00285 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
LAPPPKNL_00286 4.4e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
LAPPPKNL_00287 2e-180 iunH2 3.2.2.1 F nucleoside hydrolase
LAPPPKNL_00288 2.7e-100 S ABC-type cobalt transport system, permease component
LAPPPKNL_00289 9.2e-256 cbiO1 S ABC transporter, ATP-binding protein
LAPPPKNL_00290 1.8e-113 P Cobalt transport protein
LAPPPKNL_00291 3e-17 yvlA
LAPPPKNL_00292 0.0 yjcE P Sodium proton antiporter
LAPPPKNL_00293 6.9e-192 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
LAPPPKNL_00294 7.8e-73 O OsmC-like protein
LAPPPKNL_00295 2.8e-187 D Alpha beta
LAPPPKNL_00296 8.4e-75 K Transcriptional regulator
LAPPPKNL_00297 4.5e-160
LAPPPKNL_00298 6.6e-20
LAPPPKNL_00299 2.1e-59
LAPPPKNL_00300 3.1e-75 uspA T universal stress protein
LAPPPKNL_00302 9.7e-130 qmcA O prohibitin homologues
LAPPPKNL_00303 5.5e-245 glpT G Major Facilitator Superfamily
LAPPPKNL_00304 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LAPPPKNL_00305 3e-136 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
LAPPPKNL_00306 1.7e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LAPPPKNL_00307 6.3e-127 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LAPPPKNL_00309 5.7e-76 yphH S Cupin domain
LAPPPKNL_00311 3.5e-85 K GNAT family
LAPPPKNL_00312 8.9e-122 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
LAPPPKNL_00313 4e-161 ytbE 1.1.1.346 S Aldo keto reductase
LAPPPKNL_00314 1.7e-145 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LAPPPKNL_00315 3.3e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
LAPPPKNL_00317 3.6e-57
LAPPPKNL_00319 2.3e-07
LAPPPKNL_00320 4e-78 K Winged helix DNA-binding domain
LAPPPKNL_00321 0.0 lmrA V ABC transporter, ATP-binding protein
LAPPPKNL_00322 0.0 yfiC V ABC transporter
LAPPPKNL_00323 4.8e-193 ampC V Beta-lactamase
LAPPPKNL_00324 7.8e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LAPPPKNL_00325 2.8e-48
LAPPPKNL_00326 3.4e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
LAPPPKNL_00327 7.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
LAPPPKNL_00328 3.2e-109 tdk 2.7.1.21 F thymidine kinase
LAPPPKNL_00329 2.5e-155 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LAPPPKNL_00330 1.3e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LAPPPKNL_00331 2.3e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LAPPPKNL_00332 5e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LAPPPKNL_00333 1.2e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LAPPPKNL_00334 1.7e-183 yibE S overlaps another CDS with the same product name
LAPPPKNL_00335 5.5e-125 yibF S overlaps another CDS with the same product name
LAPPPKNL_00336 5.4e-218 pyrP F Permease
LAPPPKNL_00337 5.8e-129 atpB C it plays a direct role in the translocation of protons across the membrane
LAPPPKNL_00338 1.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LAPPPKNL_00339 2.6e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LAPPPKNL_00340 2.8e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LAPPPKNL_00341 6.2e-285 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LAPPPKNL_00342 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LAPPPKNL_00343 1.3e-252 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LAPPPKNL_00344 4.4e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LAPPPKNL_00345 2.8e-29 S Protein of unknown function (DUF1146)
LAPPPKNL_00346 1.8e-218 murA 2.5.1.7 M EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
LAPPPKNL_00347 2.6e-183 mbl D Cell shape determining protein MreB Mrl
LAPPPKNL_00348 7.9e-32 S Protein of unknown function (DUF2969)
LAPPPKNL_00349 5.8e-222 rodA D Belongs to the SEDS family
LAPPPKNL_00351 5.3e-181 S Protein of unknown function (DUF2785)
LAPPPKNL_00352 7.7e-216 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LAPPPKNL_00353 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LAPPPKNL_00354 1.6e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LAPPPKNL_00358 8.2e-31 S zinc-ribbon domain
LAPPPKNL_00359 1.1e-40
LAPPPKNL_00360 3.2e-36 M LysM domain
LAPPPKNL_00361 3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LAPPPKNL_00362 2.9e-211 EG GntP family permease
LAPPPKNL_00363 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LAPPPKNL_00364 2.9e-215 iscS2 2.8.1.7 E Aminotransferase class V
LAPPPKNL_00365 2.2e-307 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LAPPPKNL_00366 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LAPPPKNL_00367 2e-68 V Abi-like protein
LAPPPKNL_00368 4.8e-131 M lysozyme activity
LAPPPKNL_00369 1e-20 S Bacteriophage holin family
LAPPPKNL_00372 9.2e-222 S peptidoglycan catabolic process
LAPPPKNL_00373 1.6e-63 S Phage tail protein
LAPPPKNL_00374 1.5e-165 S peptidoglycan catabolic process
LAPPPKNL_00375 2.2e-38 S Pfam:Phage_TAC_12
LAPPPKNL_00376 4e-83 S Phage major tail protein 2
LAPPPKNL_00377 1.2e-43
LAPPPKNL_00378 4.2e-42 S exonuclease activity
LAPPPKNL_00379 6.4e-19
LAPPPKNL_00380 7.2e-44 S Phage gp6-like head-tail connector protein
LAPPPKNL_00381 3.3e-118
LAPPPKNL_00382 2.3e-65 S aminoacyl-tRNA ligase activity
LAPPPKNL_00384 1.1e-136 S Phage Mu protein F like protein
LAPPPKNL_00385 1.4e-208 S Phage portal protein, SPP1 Gp6-like
LAPPPKNL_00386 1.2e-189 S Phage terminase, large subunit
LAPPPKNL_00388 1.1e-09 L Terminase small subunit
LAPPPKNL_00391 0.0 pepN 3.4.11.2 E aminopeptidase
LAPPPKNL_00392 3.5e-35 morA C Aldo keto reductase
LAPPPKNL_00393 9.3e-164 K Transcriptional regulator
LAPPPKNL_00394 3e-24 phaG GT1 I carboxylic ester hydrolase activity
LAPPPKNL_00395 2.1e-140 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LAPPPKNL_00397 4.3e-155 metQ_4 P Belongs to the nlpA lipoprotein family
LAPPPKNL_00398 4e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LAPPPKNL_00399 0.0 helD 3.6.4.12 L DNA helicase
LAPPPKNL_00400 6.6e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
LAPPPKNL_00401 6.2e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LAPPPKNL_00402 2.2e-187
LAPPPKNL_00403 4.4e-129 cobB K SIR2 family
LAPPPKNL_00404 5.3e-212 norA EGP Major facilitator Superfamily
LAPPPKNL_00405 1.2e-162 yunF F Protein of unknown function DUF72
LAPPPKNL_00406 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LAPPPKNL_00407 1.8e-147 tatD L hydrolase, TatD family
LAPPPKNL_00408 1.9e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LAPPPKNL_00409 2.5e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LAPPPKNL_00410 1.3e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LAPPPKNL_00411 1.3e-165 znuA P Belongs to the bacterial solute-binding protein 9 family
LAPPPKNL_00412 5.4e-95 fhuC P ABC transporter
LAPPPKNL_00413 3.2e-128 znuB U ABC 3 transport family
LAPPPKNL_00414 7.5e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LAPPPKNL_00415 1.3e-204 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LAPPPKNL_00416 3.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LAPPPKNL_00417 3e-32
LAPPPKNL_00418 4.8e-143 yxeH S hydrolase
LAPPPKNL_00419 1.5e-266 ywfO S HD domain protein
LAPPPKNL_00420 3.2e-74 ywiB S Domain of unknown function (DUF1934)
LAPPPKNL_00421 1.6e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LAPPPKNL_00422 1.1e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LAPPPKNL_00423 2.3e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LAPPPKNL_00424 6e-41 rpmE2 J Ribosomal protein L31
LAPPPKNL_00425 1.3e-49 mdtG EGP Major facilitator Superfamily
LAPPPKNL_00426 1.5e-55 mdtG EGP Major facilitator Superfamily
LAPPPKNL_00427 1.1e-250 malT G Major Facilitator
LAPPPKNL_00428 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
LAPPPKNL_00429 1.4e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
LAPPPKNL_00430 1.1e-110 ysdA CP transmembrane transport
LAPPPKNL_00431 5.3e-189 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LAPPPKNL_00432 1.1e-46 D Alpha beta
LAPPPKNL_00433 8.7e-56 D Alpha beta
LAPPPKNL_00434 7.5e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAPPPKNL_00435 2.7e-216 patA 2.6.1.1 E Aminotransferase
LAPPPKNL_00436 1e-34
LAPPPKNL_00437 0.0 clpL O associated with various cellular activities
LAPPPKNL_00438 6.9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LAPPPKNL_00439 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LAPPPKNL_00440 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LAPPPKNL_00441 2.6e-163 yvgN C Aldo keto reductase
LAPPPKNL_00442 1.1e-289 glpQ 3.1.4.46 C phosphodiesterase
LAPPPKNL_00443 1.7e-65 arsC 1.20.4.1 P Belongs to the ArsC family
LAPPPKNL_00444 3.9e-188 ybhR V ABC transporter
LAPPPKNL_00445 3e-128 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
LAPPPKNL_00446 4e-93 K transcriptional regulator
LAPPPKNL_00447 4.8e-166 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LAPPPKNL_00448 1.2e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LAPPPKNL_00449 1.3e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
LAPPPKNL_00450 1.9e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LAPPPKNL_00451 1.4e-130 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LAPPPKNL_00452 8.5e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LAPPPKNL_00453 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LAPPPKNL_00454 1.2e-244 fucP G Major Facilitator Superfamily
LAPPPKNL_00455 2.1e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LAPPPKNL_00456 7.2e-164 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LAPPPKNL_00457 1.4e-170 deoR K sugar-binding domain protein
LAPPPKNL_00458 9.8e-115 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LAPPPKNL_00459 4e-200 S Domain of unknown function (DUF4432)
LAPPPKNL_00460 3.2e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LAPPPKNL_00461 1.1e-259 G PTS system Galactitol-specific IIC component
LAPPPKNL_00462 4.7e-185 K helix_turn _helix lactose operon repressor
LAPPPKNL_00463 2.2e-279 yjeM E Amino Acid
LAPPPKNL_00465 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
LAPPPKNL_00466 1.1e-149 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
LAPPPKNL_00467 6.4e-131 gntR K UbiC transcription regulator-associated domain protein
LAPPPKNL_00468 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LAPPPKNL_00469 3.2e-130
LAPPPKNL_00470 1e-265 pipD E Dipeptidase
LAPPPKNL_00471 2.6e-157 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
LAPPPKNL_00472 8.9e-87 M1-874 K Domain of unknown function (DUF1836)
LAPPPKNL_00473 1.5e-89 GM epimerase
LAPPPKNL_00474 4e-251 yhdP S Transporter associated domain
LAPPPKNL_00475 2.4e-83 nrdI F Belongs to the NrdI family
LAPPPKNL_00476 6.5e-75 S 3-demethylubiquinone-9 3-methyltransferase
LAPPPKNL_00477 2.8e-205 yeaN P Transporter, major facilitator family protein
LAPPPKNL_00478 2.9e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LAPPPKNL_00479 5.8e-65 S module of peptide synthetase
LAPPPKNL_00480 1.5e-245 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LAPPPKNL_00481 7.4e-83 iolS C Aldo keto reductase
LAPPPKNL_00482 1.3e-243 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LAPPPKNL_00483 1.2e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LAPPPKNL_00484 4.8e-240 dltB M MBOAT, membrane-bound O-acyltransferase family
LAPPPKNL_00485 8.3e-298 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LAPPPKNL_00487 8.7e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LAPPPKNL_00488 0.0 sbcC L Putative exonuclease SbcCD, C subunit
LAPPPKNL_00489 2.1e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LAPPPKNL_00490 3.2e-189 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
LAPPPKNL_00492 3.7e-223 glnP P ABC transporter
LAPPPKNL_00493 1e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LAPPPKNL_00494 6.4e-249 cycA E Amino acid permease
LAPPPKNL_00495 2.9e-213 nupG F Nucleoside transporter
LAPPPKNL_00496 2.2e-144 rihC 3.2.2.1 F Nucleoside
LAPPPKNL_00497 2e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
LAPPPKNL_00498 8.4e-152 noc K Belongs to the ParB family
LAPPPKNL_00499 5.6e-147 spo0J K Belongs to the ParB family
LAPPPKNL_00500 7.9e-31 yyzM S Bacterial protein of unknown function (DUF951)
LAPPPKNL_00501 2.8e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LAPPPKNL_00502 4.2e-133 XK27_01040 S Protein of unknown function (DUF1129)
LAPPPKNL_00503 3.5e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LAPPPKNL_00504 0.0 FbpA K Fibronectin-binding protein
LAPPPKNL_00505 3.2e-161 degV S EDD domain protein, DegV family
LAPPPKNL_00506 1.3e-97
LAPPPKNL_00507 4.8e-134 S Belongs to the UPF0246 family
LAPPPKNL_00508 9.5e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LAPPPKNL_00509 5.3e-113 ylbE GM NAD(P)H-binding
LAPPPKNL_00510 3.5e-99 K Acetyltransferase (GNAT) domain
LAPPPKNL_00511 5.2e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LAPPPKNL_00512 1.2e-233 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LAPPPKNL_00513 1.6e-285 thrC 4.2.3.1 E Threonine synthase
LAPPPKNL_00514 1.8e-122 azlC E azaleucine resistance protein AzlC
LAPPPKNL_00515 2.8e-54 azlD E Branched-chain amino acid transport
LAPPPKNL_00516 4.8e-183 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
LAPPPKNL_00517 1.3e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
LAPPPKNL_00518 1.5e-204 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LAPPPKNL_00519 3.1e-259 lpdA 1.8.1.4 C Dehydrogenase
LAPPPKNL_00520 2.3e-195 lplA 6.3.1.20 H Lipoate-protein ligase
LAPPPKNL_00521 1.5e-216 E GDSL-like Lipase/Acylhydrolase family
LAPPPKNL_00522 2.3e-33 K LysR substrate binding domain protein
LAPPPKNL_00523 4.6e-47 K LysR substrate binding domain protein
LAPPPKNL_00524 7.3e-212 naiP EGP Major facilitator Superfamily
LAPPPKNL_00525 1.2e-250 yhdP S Transporter associated domain
LAPPPKNL_00526 3.4e-201 mdtG EGP Major facilitator Superfamily
LAPPPKNL_00527 2.7e-159 EGP Major facilitator Superfamily
LAPPPKNL_00528 1.6e-168 T Calcineurin-like phosphoesterase superfamily domain
LAPPPKNL_00529 5.4e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LAPPPKNL_00530 1.8e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LAPPPKNL_00531 1.9e-164 S Alpha/beta hydrolase of unknown function (DUF915)
LAPPPKNL_00532 4.8e-276 pipD E Dipeptidase
LAPPPKNL_00533 0.0 yjbQ P TrkA C-terminal domain protein
LAPPPKNL_00534 5.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LAPPPKNL_00535 3.9e-284 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LAPPPKNL_00537 0.0 kup P Transport of potassium into the cell
LAPPPKNL_00538 1.6e-49
LAPPPKNL_00539 0.0 S Bacterial membrane protein YfhO
LAPPPKNL_00541 2.7e-237 lmrB EGP Major facilitator Superfamily
LAPPPKNL_00542 6.7e-156 S Alpha beta hydrolase
LAPPPKNL_00543 1.2e-157 1.6.5.2 GM NAD(P)H-binding
LAPPPKNL_00544 1.1e-152 S Sucrose-6F-phosphate phosphohydrolase
LAPPPKNL_00545 4.8e-242 dtpT U amino acid peptide transporter
LAPPPKNL_00547 7.1e-212 ydiN G Major Facilitator Superfamily
LAPPPKNL_00548 7.6e-13 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase type II
LAPPPKNL_00549 6.7e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LAPPPKNL_00550 1.4e-103
LAPPPKNL_00551 4.5e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LAPPPKNL_00552 6.9e-105 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LAPPPKNL_00553 2.8e-64 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LAPPPKNL_00554 3.3e-89 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LAPPPKNL_00555 1e-215 aspB E DegT/DnrJ/EryC1/StrS aminotransferase family
LAPPPKNL_00556 9.7e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAPPPKNL_00557 2.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LAPPPKNL_00558 2.4e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
LAPPPKNL_00559 1.5e-22 S Virus attachment protein p12 family
LAPPPKNL_00560 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
LAPPPKNL_00561 3.9e-33 feoA P FeoA domain
LAPPPKNL_00562 9.4e-144 sufC O FeS assembly ATPase SufC
LAPPPKNL_00563 4.5e-244 sufD O FeS assembly protein SufD
LAPPPKNL_00564 4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LAPPPKNL_00565 3.2e-83 nifU C SUF system FeS assembly protein, NifU family
LAPPPKNL_00566 4.2e-272 sufB O assembly protein SufB
LAPPPKNL_00567 3.9e-177 fecB P Periplasmic binding protein
LAPPPKNL_00568 3.2e-142 EG EamA-like transporter family
LAPPPKNL_00569 9.5e-258 XK27_04775 S PAS domain
LAPPPKNL_00570 4.7e-19 M1-755 S Domain of unknown function (DUF1858)
LAPPPKNL_00571 8e-54 yitW S Iron-sulfur cluster assembly protein
LAPPPKNL_00572 2.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
LAPPPKNL_00573 7.7e-143 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
LAPPPKNL_00574 3.3e-170 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LAPPPKNL_00575 2.2e-72 moaE 2.8.1.12 H MoaE protein
LAPPPKNL_00576 6.4e-35 moaD 2.8.1.12 H ThiS family
LAPPPKNL_00577 3.5e-196 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LAPPPKNL_00578 3.6e-216 narK P Major Facilitator Superfamily
LAPPPKNL_00579 1.5e-58 yitW S Iron-sulfur cluster assembly protein
LAPPPKNL_00580 4.5e-163 hipB K Helix-turn-helix
LAPPPKNL_00581 3.9e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LAPPPKNL_00583 2e-169 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
LAPPPKNL_00584 3e-184
LAPPPKNL_00585 1.2e-39
LAPPPKNL_00586 3e-116 nreC K PFAM regulatory protein LuxR
LAPPPKNL_00587 7.9e-183 comP 2.7.13.3 F Sensor histidine kinase
LAPPPKNL_00588 1.4e-77 nreA T GAF domain
LAPPPKNL_00589 4.2e-40
LAPPPKNL_00590 1.1e-98 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LAPPPKNL_00591 7.2e-85 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LAPPPKNL_00592 1.5e-230 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
LAPPPKNL_00593 1.9e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
LAPPPKNL_00594 2e-188 moeB 2.7.7.73, 2.7.7.80 H ThiF family
LAPPPKNL_00595 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LAPPPKNL_00596 0.0 narH 1.7.5.1 C Respiratory nitrate reductase beta C-terminal
LAPPPKNL_00597 9.2e-102 narJ C Nitrate reductase delta subunit
LAPPPKNL_00598 8.7e-130 narI 1.7.5.1 C Nitrate reductase
LAPPPKNL_00599 1.3e-184
LAPPPKNL_00600 5.9e-76
LAPPPKNL_00601 7.2e-66 yjcE P Sodium proton antiporter
LAPPPKNL_00602 1.2e-48 ywnB S NAD(P)H-binding
LAPPPKNL_00603 3.4e-288 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
LAPPPKNL_00604 2.2e-96 V VanZ like family
LAPPPKNL_00605 1.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LAPPPKNL_00606 2.5e-61 yneR
LAPPPKNL_00607 2.2e-182 K Transcriptional regulator, LacI family
LAPPPKNL_00608 3.2e-229 gntT EG Gluconate
LAPPPKNL_00609 1.2e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
LAPPPKNL_00610 9.1e-107 mutR K Transcriptional activator, Rgg GadR MutR family
LAPPPKNL_00611 4.3e-50 mutR K Transcriptional activator, Rgg GadR MutR family
LAPPPKNL_00612 1.2e-11 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LAPPPKNL_00613 1.5e-46 3.6.3.6 P ATPase, P-type transporting, HAD superfamily, subfamily IC
LAPPPKNL_00615 1.2e-79 copY K Copper transport repressor CopY TcrY
LAPPPKNL_00616 3.9e-41
LAPPPKNL_00617 2e-169 GK ROK family
LAPPPKNL_00618 2.9e-87 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LAPPPKNL_00619 4.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
LAPPPKNL_00620 1.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
LAPPPKNL_00621 1.9e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LAPPPKNL_00622 2.1e-79 K 2 iron, 2 sulfur cluster binding
LAPPPKNL_00623 3.3e-266 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
LAPPPKNL_00624 4.8e-221 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAPPPKNL_00625 5.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LAPPPKNL_00626 3.2e-112 C aldo keto reductase
LAPPPKNL_00627 1.9e-112 3.1.3.73 G phosphoglycerate mutase
LAPPPKNL_00628 5.6e-09
LAPPPKNL_00629 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LAPPPKNL_00630 5.1e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LAPPPKNL_00631 3.7e-51 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
LAPPPKNL_00632 8.5e-56 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LAPPPKNL_00633 1.9e-141 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LAPPPKNL_00634 2.7e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LAPPPKNL_00635 1.2e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LAPPPKNL_00636 1.9e-101 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LAPPPKNL_00637 4.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LAPPPKNL_00638 5.8e-109 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LAPPPKNL_00639 1.4e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LAPPPKNL_00640 8.9e-169 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
LAPPPKNL_00641 5e-51 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LAPPPKNL_00642 2.9e-08 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LAPPPKNL_00643 2.4e-95 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LAPPPKNL_00644 1.1e-177 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LAPPPKNL_00645 0.0 dnaK O Heat shock 70 kDa protein
LAPPPKNL_00646 4.9e-57 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LAPPPKNL_00647 5.4e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LAPPPKNL_00648 2e-61
LAPPPKNL_00649 8e-274 nylA 3.5.1.4 J Belongs to the amidase family
LAPPPKNL_00650 6.2e-127 arcD S C4-dicarboxylate anaerobic carrier
LAPPPKNL_00651 8.5e-215 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LAPPPKNL_00652 8.9e-83 F Hydrolase, NUDIX family
LAPPPKNL_00653 1.2e-211 S Type IV secretion-system coupling protein DNA-binding domain
LAPPPKNL_00654 0.0 tetP J elongation factor G
LAPPPKNL_00655 4.6e-58 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LAPPPKNL_00656 3.5e-111 ypsA S Belongs to the UPF0398 family
LAPPPKNL_00657 1e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LAPPPKNL_00658 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
LAPPPKNL_00659 3.7e-160 EG EamA-like transporter family
LAPPPKNL_00660 1.4e-192 C Aldo keto reductase family protein
LAPPPKNL_00661 3.7e-121 ypuA S Protein of unknown function (DUF1002)
LAPPPKNL_00662 4.7e-134 dnaD L DnaD domain protein
LAPPPKNL_00663 2.1e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
LAPPPKNL_00664 1.6e-88 ypmB S Protein conserved in bacteria
LAPPPKNL_00665 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LAPPPKNL_00666 2.2e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
LAPPPKNL_00667 8.2e-182 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LAPPPKNL_00668 3.3e-211 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
LAPPPKNL_00669 1.5e-205 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LAPPPKNL_00670 9e-96 pstB 3.6.3.27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LAPPPKNL_00671 5.9e-82 S Psort location Cytoplasmic, score
LAPPPKNL_00672 1.9e-286 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
LAPPPKNL_00673 1.1e-95 wecD K Acetyltransferase (GNAT) family
LAPPPKNL_00674 6.4e-105 3.2.1.17 NU mannosyl-glycoprotein
LAPPPKNL_00675 1.1e-194 asnA 6.3.1.1 F aspartate--ammonia ligase
LAPPPKNL_00676 2.4e-35 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LAPPPKNL_00677 4.9e-215 2.1.1.14 E methionine synthase, vitamin-B12 independent
LAPPPKNL_00678 3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LAPPPKNL_00679 3.5e-38 S Cytochrome B5
LAPPPKNL_00682 1.6e-15 S Domain of unknown function (DUF4811)
LAPPPKNL_00683 2.8e-255 lmrB EGP Major facilitator Superfamily
LAPPPKNL_00684 7.7e-97 K transcriptional regulator
LAPPPKNL_00685 3.2e-71 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
LAPPPKNL_00686 0.0 L Helicase C-terminal domain protein
LAPPPKNL_00687 1.6e-54 S MazG-like family
LAPPPKNL_00688 6.1e-108 lssY 3.6.1.27 I Acid phosphatase homologues
LAPPPKNL_00689 2.9e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
LAPPPKNL_00690 2e-97
LAPPPKNL_00691 1e-224 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LAPPPKNL_00692 2.8e-168 ponA V Beta-lactamase enzyme family
LAPPPKNL_00693 6.2e-266 yjeM E Amino Acid
LAPPPKNL_00695 5.5e-112
LAPPPKNL_00696 6.8e-164 S Polyphosphate nucleotide phosphotransferase, PPK2 family
LAPPPKNL_00697 3.2e-164 K LysR substrate binding domain
LAPPPKNL_00698 2e-80 K FR47-like protein
LAPPPKNL_00699 7.8e-299 ybeC E amino acid
LAPPPKNL_00700 1.2e-134 pnuC H nicotinamide mononucleotide transporter
LAPPPKNL_00701 7.5e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LAPPPKNL_00702 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LAPPPKNL_00703 4e-121 pgm7 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
LAPPPKNL_00704 4e-116 dedA S SNARE associated Golgi protein
LAPPPKNL_00705 0.0 helD 3.6.4.12 L DNA helicase
LAPPPKNL_00706 2.5e-161 EG EamA-like transporter family
LAPPPKNL_00707 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LAPPPKNL_00708 3.4e-135 IQ Dehydrogenase reductase
LAPPPKNL_00709 3.3e-82 2.3.1.128 K acetyltransferase
LAPPPKNL_00710 5.3e-175 coaA 2.7.1.33 F Pantothenic acid kinase
LAPPPKNL_00711 1.3e-131 sptS 2.7.13.3 T Histidine kinase
LAPPPKNL_00712 4e-79 K response regulator
LAPPPKNL_00713 1.1e-112 2.7.6.5 T Region found in RelA / SpoT proteins
LAPPPKNL_00714 5.7e-270 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LAPPPKNL_00715 1.6e-85 S KAP family P-loop domain
LAPPPKNL_00716 9.2e-273 2.1.1.72 V type I restriction-modification system
LAPPPKNL_00718 8.9e-232 yfmL 3.6.4.13 L DEAD DEAH box helicase
LAPPPKNL_00719 1.3e-190 mocA S Oxidoreductase
LAPPPKNL_00720 4.9e-63 S Domain of unknown function (DUF4828)
LAPPPKNL_00721 5.2e-104 yvdD 3.2.2.10 S Belongs to the LOG family
LAPPPKNL_00722 1.9e-161 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LAPPPKNL_00723 6.2e-290 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
LAPPPKNL_00724 3.6e-140 S NADPH-dependent FMN reductase
LAPPPKNL_00725 2.3e-33 yneR S Belongs to the HesB IscA family
LAPPPKNL_00726 2.8e-304 ybiT S ABC transporter, ATP-binding protein
LAPPPKNL_00727 1.7e-84 dps P Belongs to the Dps family
LAPPPKNL_00728 6e-105
LAPPPKNL_00729 1.5e-183 brpA K Cell envelope-like function transcriptional attenuator common domain protein
LAPPPKNL_00730 2.3e-101 K helix_turn_helix multiple antibiotic resistance protein
LAPPPKNL_00731 3.4e-49 fsr EGP Major Facilitator Superfamily
LAPPPKNL_00732 1.1e-78 fsr EGP Major Facilitator Superfamily
LAPPPKNL_00733 9.2e-100 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LAPPPKNL_00734 7.8e-103 S CAAX protease self-immunity
LAPPPKNL_00736 4.1e-119 Q Methyltransferase domain
LAPPPKNL_00737 1.2e-60 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
LAPPPKNL_00738 5.6e-20 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
LAPPPKNL_00739 2.8e-51 K 2 iron, 2 sulfur cluster binding
LAPPPKNL_00740 0.0 mco Q Multicopper oxidase
LAPPPKNL_00741 7.1e-89 S Aminoacyl-tRNA editing domain
LAPPPKNL_00742 3.1e-75 ddaH 3.5.3.18 E Amidinotransferase
LAPPPKNL_00744 7e-195 nhaC C Na H antiporter NhaC
LAPPPKNL_00745 4.7e-123 srtA 3.4.22.70 M sortase family
LAPPPKNL_00746 3.1e-46 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LAPPPKNL_00747 1.9e-87 lemA S LemA family
LAPPPKNL_00748 4.9e-157 htpX O Belongs to the peptidase M48B family
LAPPPKNL_00749 2.1e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LAPPPKNL_00750 6.6e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LAPPPKNL_00751 2.9e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LAPPPKNL_00752 9.6e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LAPPPKNL_00753 5e-57 L Toxic component of a toxin-antitoxin (TA) module
LAPPPKNL_00754 8.1e-114 S (CBS) domain
LAPPPKNL_00755 8.2e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LAPPPKNL_00756 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LAPPPKNL_00757 1.6e-39 yabO J S4 domain protein
LAPPPKNL_00758 1.5e-56 divIC D Septum formation initiator
LAPPPKNL_00759 3e-87 yabR J RNA binding
LAPPPKNL_00760 9e-256 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LAPPPKNL_00761 4.1e-98 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LAPPPKNL_00762 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LAPPPKNL_00763 1.3e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LAPPPKNL_00764 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LAPPPKNL_00765 1.2e-290 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LAPPPKNL_00766 2.4e-101 K DNA-templated transcription, initiation
LAPPPKNL_00768 0.0 N Uncharacterized conserved protein (DUF2075)
LAPPPKNL_00769 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LAPPPKNL_00770 2.8e-114 ybbL S ABC transporter, ATP-binding protein
LAPPPKNL_00771 8.5e-130 ybbM S Uncharacterised protein family (UPF0014)
LAPPPKNL_00772 7.2e-89 rmeB K transcriptional regulator, MerR family
LAPPPKNL_00773 4.9e-46 yrfB C NADH:flavin oxidoreductase / NADH oxidase family
LAPPPKNL_00774 2.2e-113 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LAPPPKNL_00775 1.7e-56 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
LAPPPKNL_00777 4.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LAPPPKNL_00778 3.9e-259 guaD 3.5.4.3 F Amidohydrolase family
LAPPPKNL_00779 1.9e-37 tdh 1.1.1.14 C Zinc-binding dehydrogenase
LAPPPKNL_00780 3.1e-96 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
LAPPPKNL_00781 1.1e-30 S Sugar efflux transporter for intercellular exchange
LAPPPKNL_00782 4.7e-32 higA K Helix-turn-helix XRE-family like proteins
LAPPPKNL_00783 3.8e-126 E Amino acid permease
LAPPPKNL_00784 4.7e-10 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
LAPPPKNL_00785 5e-216 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
LAPPPKNL_00787 9.9e-39 L Bacterial dnaA protein
LAPPPKNL_00788 8.7e-176 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LAPPPKNL_00789 1.7e-97 S Pfam:DUF3816
LAPPPKNL_00790 1e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
LAPPPKNL_00791 2.6e-99 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LAPPPKNL_00792 6.5e-162 EG EamA-like transporter family
LAPPPKNL_00793 1.2e-246 yxbA 6.3.1.12 S ATP-grasp enzyme
LAPPPKNL_00795 7.2e-15
LAPPPKNL_00796 1.6e-157 V ABC transporter, ATP-binding protein
LAPPPKNL_00797 7.8e-64 gntR1 K Transcriptional regulator, GntR family
LAPPPKNL_00798 6.8e-170 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LAPPPKNL_00799 1.1e-88 S Bacterial membrane protein, YfhO
LAPPPKNL_00800 3.1e-103 glfT1 1.1.1.133 S Glycosyltransferase like family 2
LAPPPKNL_00801 3.7e-95 M transferase activity, transferring glycosyl groups
LAPPPKNL_00802 7.7e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LAPPPKNL_00803 2.6e-164 ykoT GT2 M Glycosyl transferase family 2
LAPPPKNL_00804 6.7e-140 yueF S AI-2E family transporter
LAPPPKNL_00805 2.9e-160 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
LAPPPKNL_00806 2.1e-09
LAPPPKNL_00807 1.9e-63 M repeat protein
LAPPPKNL_00808 8.5e-60 3.2.1.96, 3.5.1.28 GH73 M repeat protein
LAPPPKNL_00809 1.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
LAPPPKNL_00810 2.2e-27
LAPPPKNL_00811 3.1e-13
LAPPPKNL_00812 2.6e-236 kgtP EGP Sugar (and other) transporter
LAPPPKNL_00813 1.6e-140 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
LAPPPKNL_00814 7.5e-153 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LAPPPKNL_00815 2.8e-149 isdE P Periplasmic binding protein
LAPPPKNL_00816 1e-94 M Iron Transport-associated domain
LAPPPKNL_00817 4.5e-274 isdH M Iron Transport-associated domain
LAPPPKNL_00818 4.3e-52
LAPPPKNL_00819 1.6e-52 4.1.1.44 O Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LAPPPKNL_00820 1.5e-90 P Cadmium resistance transporter
LAPPPKNL_00824 8.1e-25 C Aldo keto reductase
LAPPPKNL_00825 2.2e-39 C Aldo keto reductase
LAPPPKNL_00826 4.1e-80 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LAPPPKNL_00827 8.7e-104 S Alpha/beta hydrolase family
LAPPPKNL_00828 2e-120 pnb C nitroreductase
LAPPPKNL_00829 7e-28 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
LAPPPKNL_00830 4.8e-17 S Tautomerase enzyme
LAPPPKNL_00831 6.1e-29 S Domain of unknown function (DUF4767)
LAPPPKNL_00834 1.3e-131 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LAPPPKNL_00835 7.8e-154 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
LAPPPKNL_00836 1.2e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LAPPPKNL_00837 3.8e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LAPPPKNL_00838 1.6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LAPPPKNL_00839 2.8e-137 cof S haloacid dehalogenase-like hydrolase
LAPPPKNL_00840 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LAPPPKNL_00841 5.2e-113 yfbR S HD containing hydrolase-like enzyme
LAPPPKNL_00843 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LAPPPKNL_00844 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LAPPPKNL_00845 1.7e-204
LAPPPKNL_00846 3.9e-159 rapZ S Displays ATPase and GTPase activities
LAPPPKNL_00847 1.7e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LAPPPKNL_00848 1.9e-167 whiA K May be required for sporulation
LAPPPKNL_00849 3.4e-120 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LAPPPKNL_00850 1.3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LAPPPKNL_00854 1.5e-179 S Phosphotransferase system, EIIC
LAPPPKNL_00855 1.5e-21 D mRNA cleavage
LAPPPKNL_00856 1.9e-21 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
LAPPPKNL_00857 7.4e-112 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LAPPPKNL_00858 2.4e-121 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LAPPPKNL_00859 3.8e-16
LAPPPKNL_00860 7.3e-64 yjbR S YjbR
LAPPPKNL_00861 6.1e-117 S Sel1-like repeats.
LAPPPKNL_00862 2.8e-89 K Psort location CytoplasmicMembrane, score
LAPPPKNL_00863 3.5e-82 K Helix-turn-helix XRE-family like proteins
LAPPPKNL_00864 2.2e-50 K TRANSCRIPTIONal
LAPPPKNL_00865 4.1e-264 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LAPPPKNL_00866 1.9e-186 yegS 2.7.1.107 G Lipid kinase
LAPPPKNL_00867 5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LAPPPKNL_00868 1.5e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LAPPPKNL_00869 1e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LAPPPKNL_00870 3.2e-166 camS S sex pheromone
LAPPPKNL_00871 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LAPPPKNL_00872 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LAPPPKNL_00873 1.4e-220 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LAPPPKNL_00874 2.7e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LAPPPKNL_00875 5.8e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
LAPPPKNL_00876 1.2e-138 IQ reductase
LAPPPKNL_00877 6.4e-191 S interspecies interaction between organisms
LAPPPKNL_00878 1.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
LAPPPKNL_00879 2.6e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LAPPPKNL_00880 6.3e-145 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LAPPPKNL_00881 1.4e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LAPPPKNL_00882 2e-155 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LAPPPKNL_00883 7.8e-149 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LAPPPKNL_00884 2.8e-61 rplQ J Ribosomal protein L17
LAPPPKNL_00885 2e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LAPPPKNL_00886 1e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LAPPPKNL_00887 9.5e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LAPPPKNL_00888 1.1e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LAPPPKNL_00889 2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LAPPPKNL_00890 6.4e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LAPPPKNL_00891 7.6e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LAPPPKNL_00892 2.1e-65 rplO J Binds to the 23S rRNA
LAPPPKNL_00893 2.5e-23 rpmD J Ribosomal protein L30
LAPPPKNL_00894 2.6e-86 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LAPPPKNL_00895 3.9e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LAPPPKNL_00896 1.9e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LAPPPKNL_00897 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LAPPPKNL_00898 5.2e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LAPPPKNL_00899 4.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LAPPPKNL_00900 5.2e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LAPPPKNL_00901 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LAPPPKNL_00902 6.5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LAPPPKNL_00903 1.1e-27 rpmC J Belongs to the universal ribosomal protein uL29 family
LAPPPKNL_00904 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LAPPPKNL_00905 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LAPPPKNL_00906 2.2e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LAPPPKNL_00907 8.4e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LAPPPKNL_00908 1.6e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LAPPPKNL_00909 4.8e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LAPPPKNL_00910 2.7e-106 rplD J Forms part of the polypeptide exit tunnel
LAPPPKNL_00911 8.7e-119 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LAPPPKNL_00912 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LAPPPKNL_00913 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LAPPPKNL_00914 7.1e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LAPPPKNL_00915 3.2e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LAPPPKNL_00916 1.6e-32 pilD 3.4.23.43 NOU aspartic-type endopeptidase activity
LAPPPKNL_00917 2.2e-213 ykiI
LAPPPKNL_00918 5.6e-135 puuD S peptidase C26
LAPPPKNL_00919 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LAPPPKNL_00920 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LAPPPKNL_00921 5.8e-106 K Bacterial regulatory proteins, tetR family
LAPPPKNL_00922 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LAPPPKNL_00923 4.8e-79 ctsR K Belongs to the CtsR family
LAPPPKNL_00924 9.7e-194 adhP 1.1.1.1 C alcohol dehydrogenase
LAPPPKNL_00925 4.3e-132 XK27_07210 6.1.1.6 S B3 4 domain
LAPPPKNL_00926 7.9e-120 J 2'-5' RNA ligase superfamily
LAPPPKNL_00928 4.8e-42 S ABC-type cobalt transport system, permease component
LAPPPKNL_00929 1.9e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LAPPPKNL_00930 1.3e-45 IQ reductase
LAPPPKNL_00931 1e-10 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LAPPPKNL_00934 7.9e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
LAPPPKNL_00935 3.9e-268 lysP E amino acid
LAPPPKNL_00937 1.4e-155 I alpha/beta hydrolase fold
LAPPPKNL_00938 1e-114 lssY 3.6.1.27 I phosphatase
LAPPPKNL_00939 2.8e-82 S Threonine/Serine exporter, ThrE
LAPPPKNL_00940 6.3e-126 thrE S Putative threonine/serine exporter
LAPPPKNL_00941 1.3e-30 cspA K Cold shock protein
LAPPPKNL_00942 1.2e-123 sirR K iron dependent repressor
LAPPPKNL_00943 1.3e-162 czcD P cation diffusion facilitator family transporter
LAPPPKNL_00944 2.5e-116 S membrane
LAPPPKNL_00945 5.8e-110 S VIT family
LAPPPKNL_00946 4.5e-85 usp1 T Belongs to the universal stress protein A family
LAPPPKNL_00947 8.1e-33 elaA S GNAT family
LAPPPKNL_00948 5.7e-217 S CAAX protease self-immunity
LAPPPKNL_00949 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LAPPPKNL_00950 5.8e-58
LAPPPKNL_00951 5.6e-74 merR K MerR HTH family regulatory protein
LAPPPKNL_00952 6.6e-268 lmrB EGP Major facilitator Superfamily
LAPPPKNL_00953 4.4e-113 S Domain of unknown function (DUF4811)
LAPPPKNL_00954 3.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
LAPPPKNL_00955 3.1e-248 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LAPPPKNL_00956 6.4e-204 araR K Transcriptional regulator
LAPPPKNL_00957 1.2e-137 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
LAPPPKNL_00958 1.3e-309 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
LAPPPKNL_00959 1.1e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LAPPPKNL_00960 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LAPPPKNL_00961 2.7e-108 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
LAPPPKNL_00962 1.6e-188 I Alpha beta
LAPPPKNL_00963 7.2e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
LAPPPKNL_00964 2.1e-252 yjjP S Putative threonine/serine exporter
LAPPPKNL_00965 1.7e-162 mleR K LysR family transcriptional regulator
LAPPPKNL_00966 1.6e-223 yflS P Sodium:sulfate symporter transmembrane region
LAPPPKNL_00967 1e-214 frdC 1.3.5.4 C FAD binding domain
LAPPPKNL_00968 6.1e-223 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LAPPPKNL_00969 1.9e-91 XK27_09620 S NADPH-dependent FMN reductase
LAPPPKNL_00970 6e-183 XK27_09615 S reductase
LAPPPKNL_00971 3.6e-230 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
LAPPPKNL_00972 5.3e-79 mleR K LysR family
LAPPPKNL_00973 1.3e-70 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LAPPPKNL_00974 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LAPPPKNL_00975 8.4e-205 rny S Endoribonuclease that initiates mRNA decay
LAPPPKNL_00976 1.1e-192 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LAPPPKNL_00977 1.6e-230 cinA 3.5.1.42 S Belongs to the CinA family
LAPPPKNL_00978 8.5e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LAPPPKNL_00979 2e-95 ymfM S Helix-turn-helix domain
LAPPPKNL_00980 2.2e-251 ymfH S Peptidase M16
LAPPPKNL_00981 1.4e-229 ymfF S Peptidase M16 inactive domain protein
LAPPPKNL_00982 1.5e-160 aatB ET ABC transporter substrate-binding protein
LAPPPKNL_00983 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LAPPPKNL_00984 1.4e-108 glnP P ABC transporter permease
LAPPPKNL_00985 6.6e-93 mreD M rod shape-determining protein MreD
LAPPPKNL_00986 3.7e-146 mreC M Involved in formation and maintenance of cell shape
LAPPPKNL_00987 1.9e-181 mreB D cell shape determining protein MreB
LAPPPKNL_00988 2.5e-115 radC L DNA repair protein
LAPPPKNL_00989 1e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LAPPPKNL_00990 2.2e-99 padR K Virulence activator alpha C-term
LAPPPKNL_00991 3.4e-79 ndk 2.7.4.6 F Belongs to the NDK family
LAPPPKNL_00992 5.3e-25 S SNARE associated Golgi protein
LAPPPKNL_00993 2.8e-13 S SNARE associated Golgi protein
LAPPPKNL_00994 7.8e-238 N Uncharacterized conserved protein (DUF2075)
LAPPPKNL_00995 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LAPPPKNL_00997 1.1e-253 yifK E Amino acid permease
LAPPPKNL_00999 3.6e-39 pipD E Dipeptidase
LAPPPKNL_01000 1.5e-216 pipD E Dipeptidase
LAPPPKNL_01001 1.2e-163 endA F DNA RNA non-specific endonuclease
LAPPPKNL_01002 1.4e-164 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
LAPPPKNL_01003 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LAPPPKNL_01004 3.1e-153 S Alpha/beta hydrolase of unknown function (DUF915)
LAPPPKNL_01006 9.2e-228
LAPPPKNL_01007 2.6e-194 V Beta-lactamase
LAPPPKNL_01008 3.2e-89 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
LAPPPKNL_01009 5.5e-78 S membrane transporter protein
LAPPPKNL_01010 2.2e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
LAPPPKNL_01011 8.6e-235 mepA V MATE efflux family protein
LAPPPKNL_01012 5.7e-225 amtB P ammonium transporter
LAPPPKNL_01014 1.2e-132 XK27_08845 S ABC transporter, ATP-binding protein
LAPPPKNL_01015 1e-138 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
LAPPPKNL_01016 5.9e-180 ABC-SBP S ABC transporter
LAPPPKNL_01017 4.9e-290 S ABC transporter, ATP-binding protein
LAPPPKNL_01018 8.9e-206 nrnB S DHHA1 domain
LAPPPKNL_01020 3e-110 M ErfK YbiS YcfS YnhG
LAPPPKNL_01021 1.4e-83 nrdI F NrdI Flavodoxin like
LAPPPKNL_01022 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LAPPPKNL_01023 8.8e-170 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
LAPPPKNL_01024 1.2e-182 1.17.4.1 F Ribonucleotide reductase, small chain
LAPPPKNL_01025 1.7e-275 S Uncharacterized protein conserved in bacteria (DUF2325)
LAPPPKNL_01026 3.2e-175 malR K Transcriptional regulator, LacI family
LAPPPKNL_01027 5.7e-71 K Transcriptional regulator
LAPPPKNL_01028 3e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LAPPPKNL_01029 6.6e-208 htrA 3.4.21.107 O serine protease
LAPPPKNL_01030 7.8e-154 vicX 3.1.26.11 S domain protein
LAPPPKNL_01031 8e-143 yycI S YycH protein
LAPPPKNL_01032 3e-240 yycH S YycH protein
LAPPPKNL_01033 0.0 vicK 2.7.13.3 T Histidine kinase
LAPPPKNL_01034 6.8e-130 K response regulator
LAPPPKNL_01035 6.3e-50
LAPPPKNL_01036 2.2e-205 lmrP E Major Facilitator Superfamily
LAPPPKNL_01037 6.3e-244 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LAPPPKNL_01038 1.2e-74 rplI J Binds to the 23S rRNA
LAPPPKNL_01039 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LAPPPKNL_01040 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LAPPPKNL_01041 9.3e-90 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LAPPPKNL_01042 3.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
LAPPPKNL_01043 9e-92 S Cupin superfamily (DUF985)
LAPPPKNL_01044 1.8e-122 K response regulator
LAPPPKNL_01045 7.7e-208 hpk31 2.7.13.3 T Histidine kinase
LAPPPKNL_01046 2.2e-203 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LAPPPKNL_01047 1.2e-149 azlC E AzlC protein
LAPPPKNL_01048 8.9e-61 azlD S branched-chain amino acid
LAPPPKNL_01049 2.2e-99 ydeN S Serine hydrolase
LAPPPKNL_01050 6.8e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LAPPPKNL_01051 1.6e-11 K transcriptional regulator
LAPPPKNL_01052 6.9e-163 K AI-2E family transporter
LAPPPKNL_01053 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LAPPPKNL_01054 1.8e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LAPPPKNL_01055 7.7e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LAPPPKNL_01056 1.2e-254 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LAPPPKNL_01057 6.1e-172 hrpQ 4.6.1.1 T histone H2A K63-linked ubiquitination
LAPPPKNL_01059 5.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LAPPPKNL_01060 1.7e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LAPPPKNL_01061 2.9e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
LAPPPKNL_01062 1.7e-117 ktrA P domain protein
LAPPPKNL_01063 6.7e-227 ktrB P Potassium uptake protein
LAPPPKNL_01064 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LAPPPKNL_01065 6.5e-218 patA 2.6.1.1 E Aminotransferase
LAPPPKNL_01066 6.2e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LAPPPKNL_01067 9.2e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LAPPPKNL_01068 1.7e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LAPPPKNL_01069 2.9e-72 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LAPPPKNL_01070 2.4e-253 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LAPPPKNL_01071 4.5e-263 lysC 2.7.2.4 E Belongs to the aspartokinase family
LAPPPKNL_01072 3.5e-180 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LAPPPKNL_01073 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LAPPPKNL_01074 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LAPPPKNL_01075 9.6e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LAPPPKNL_01076 2.2e-34 yaaA S S4 domain protein YaaA
LAPPPKNL_01077 1.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LAPPPKNL_01078 5.2e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LAPPPKNL_01079 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
LAPPPKNL_01080 1.4e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LAPPPKNL_01081 3.4e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LAPPPKNL_01082 1.4e-153 jag S R3H domain protein
LAPPPKNL_01083 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LAPPPKNL_01084 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LAPPPKNL_01085 2.3e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
LAPPPKNL_01086 1.4e-178 3.4.11.5 E Releases the N-terminal proline from various substrates
LAPPPKNL_01087 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LAPPPKNL_01088 4.4e-205 yfnA E Amino Acid
LAPPPKNL_01089 1.3e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
LAPPPKNL_01090 1.7e-105 gmk2 2.7.4.8 F Guanylate kinase
LAPPPKNL_01091 1.2e-82 zur P Belongs to the Fur family
LAPPPKNL_01093 4.4e-169
LAPPPKNL_01094 1.1e-187 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LAPPPKNL_01095 2.3e-93 K Transcriptional regulator (TetR family)
LAPPPKNL_01096 2.6e-206 V domain protein
LAPPPKNL_01097 8.6e-142 L An automated process has identified a potential problem with this gene model
LAPPPKNL_01098 9e-147 D CobQ CobB MinD ParA nucleotide binding domain protein
LAPPPKNL_01100 2.5e-26 repA S Replication initiator protein A
LAPPPKNL_01101 3.2e-77 repA S Replication initiator protein A
LAPPPKNL_01102 3.1e-41 relB L Addiction module antitoxin, RelB DinJ family
LAPPPKNL_01103 1.1e-26
LAPPPKNL_01104 3.7e-117 S protein conserved in bacteria
LAPPPKNL_01105 1.4e-41
LAPPPKNL_01106 6.1e-26
LAPPPKNL_01107 0.0 L MobA MobL family protein
LAPPPKNL_01108 6.7e-259 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
LAPPPKNL_01109 4.5e-49 K DNA-binding transcription factor activity
LAPPPKNL_01110 1.1e-62 S SnoaL-like domain
LAPPPKNL_01111 1.4e-272 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
LAPPPKNL_01112 1.2e-154 yitU 3.1.3.104 S hydrolase
LAPPPKNL_01113 3.4e-166 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LAPPPKNL_01114 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LAPPPKNL_01115 3.3e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LAPPPKNL_01116 3.3e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LAPPPKNL_01117 5.6e-183 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LAPPPKNL_01118 4.5e-47 ycsI S Protein of unknown function (DUF1445)
LAPPPKNL_01119 6.3e-157 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
LAPPPKNL_01120 7.5e-202 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
LAPPPKNL_01121 4.5e-260 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LAPPPKNL_01122 1e-27 XK27_02560 S Pfam:DUF59
LAPPPKNL_01123 2.6e-127 yocS S Transporter
LAPPPKNL_01124 1.9e-237 ydjE EGP Major facilitator Superfamily
LAPPPKNL_01125 8.1e-196 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LAPPPKNL_01126 3.5e-279 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LAPPPKNL_01127 1.1e-106 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LAPPPKNL_01128 6.7e-147 sua5 2.7.7.87 J Telomere recombination
LAPPPKNL_01130 5.6e-61 ybbM S Uncharacterised protein family (UPF0014)
LAPPPKNL_01132 4.8e-15 ydjK G Sugar (and other) transporter
LAPPPKNL_01133 4.6e-83 ydjK G Major Facilitator
LAPPPKNL_01135 1.7e-56 S Enoyl-(Acyl carrier protein) reductase
LAPPPKNL_01136 1.4e-27 IQ oxidoreductase activity
LAPPPKNL_01137 6.5e-50 C Flavodoxin
LAPPPKNL_01138 6.8e-51 yicL EG EamA-like transporter family
LAPPPKNL_01139 5.3e-78 yicL EG EamA-like transporter family
LAPPPKNL_01140 1.3e-105 L Integrase
LAPPPKNL_01141 3.3e-45 K transcriptional regulator
LAPPPKNL_01142 1.3e-108 GM NmrA-like family
LAPPPKNL_01143 3.9e-17 C Flavodoxin
LAPPPKNL_01144 2e-73 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
LAPPPKNL_01145 4.2e-74 O OsmC-like protein
LAPPPKNL_01146 5.6e-77 K Transcriptional regulator
LAPPPKNL_01147 5.1e-162 proX M ABC transporter, substrate-binding protein, QAT family
LAPPPKNL_01148 1.8e-108 proWZ P ABC transporter permease
LAPPPKNL_01149 2.7e-140 proV E ABC transporter, ATP-binding protein
LAPPPKNL_01150 3.1e-102 proW P ABC transporter, permease protein
LAPPPKNL_01151 3.6e-151 C Zinc-binding dehydrogenase
LAPPPKNL_01152 1.8e-195 bdhA 1.1.1.303, 1.1.1.4 C Zinc-binding dehydrogenase
LAPPPKNL_01153 1.9e-225 4.4.1.8 E Aminotransferase, class I
LAPPPKNL_01154 1.2e-179 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LAPPPKNL_01155 3.2e-203 xerS L Belongs to the 'phage' integrase family
LAPPPKNL_01156 4e-62 ywkB S Membrane transport protein
LAPPPKNL_01157 4.4e-180 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
LAPPPKNL_01158 1.4e-37 icd 1.1.1.42 C Isocitrate/isopropylmalate dehydrogenase
LAPPPKNL_01159 8.3e-151 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
LAPPPKNL_01160 2.6e-80 hmpT S ECF-type riboflavin transporter, S component
LAPPPKNL_01161 1e-167 1.1.1.346 C Aldo keto reductase
LAPPPKNL_01162 1.5e-161 S DUF218 domain
LAPPPKNL_01164 1.3e-96 K Acetyltransferase (GNAT) domain
LAPPPKNL_01165 5.1e-164 I alpha/beta hydrolase fold
LAPPPKNL_01166 1.4e-60 S Phage minor capsid protein 2
LAPPPKNL_01167 8.9e-35 S Phage minor capsid protein 2
LAPPPKNL_01170 1.1e-55 2.6.1.1 E Aminotransferase
LAPPPKNL_01171 2.9e-145 2.6.1.1 E Aminotransferase
LAPPPKNL_01172 1.3e-180 1.4.1.1, 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
LAPPPKNL_01173 2.7e-247 EGP Sugar (and other) transporter
LAPPPKNL_01174 4.6e-97 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
LAPPPKNL_01175 1.3e-90 S Fic/DOC family
LAPPPKNL_01176 6.7e-35 yncA 2.3.1.79 S Maltose acetyltransferase
LAPPPKNL_01177 4.3e-09 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
LAPPPKNL_01178 5.3e-105 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
LAPPPKNL_01179 4.5e-199 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LAPPPKNL_01180 5.4e-262 arcD E Amino acid permease
LAPPPKNL_01181 1.4e-117 5.1.1.13 M racemase activity, acting on amino acids and derivatives
LAPPPKNL_01182 7.9e-158 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
LAPPPKNL_01183 7.3e-28 clcA P chloride
LAPPPKNL_01184 4.3e-66 clcA P chloride
LAPPPKNL_01185 7.2e-17 lmrB EGP Major facilitator Superfamily
LAPPPKNL_01187 2.9e-246 yhjX P Major Facilitator Superfamily
LAPPPKNL_01188 4.7e-120 S Protein of unknown function (DUF554)
LAPPPKNL_01189 2.8e-257 rarA L recombination factor protein RarA
LAPPPKNL_01191 0.0 oppD EP Psort location Cytoplasmic, score
LAPPPKNL_01192 8e-243 codA 3.5.4.1 F cytosine deaminase
LAPPPKNL_01193 4.7e-244 U Belongs to the purine-cytosine permease (2.A.39) family
LAPPPKNL_01194 2.2e-81 yebR 1.8.4.14 T GAF domain-containing protein
LAPPPKNL_01195 5.7e-94 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
LAPPPKNL_01196 3.4e-76 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LAPPPKNL_01197 2.3e-71 yqkB S Belongs to the HesB IscA family
LAPPPKNL_01198 7.3e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
LAPPPKNL_01199 5.2e-95 S Protein of unknown function (DUF1440)
LAPPPKNL_01200 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LAPPPKNL_01201 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LAPPPKNL_01202 8e-103 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LAPPPKNL_01203 4e-172 lacX 5.1.3.3 G Aldose 1-epimerase
LAPPPKNL_01204 3.6e-154 D DNA integration
LAPPPKNL_01205 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LAPPPKNL_01206 8.1e-165 dprA LU DNA protecting protein DprA
LAPPPKNL_01207 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LAPPPKNL_01208 3.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LAPPPKNL_01209 3.1e-36 yozE S Belongs to the UPF0346 family
LAPPPKNL_01210 7.1e-104 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
LAPPPKNL_01211 1.1e-167 ypmR E lipolytic protein G-D-S-L family
LAPPPKNL_01212 2.2e-108 cat S Bacterial transferase hexapeptide (six repeats)
LAPPPKNL_01213 2.9e-218 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase
LAPPPKNL_01214 1.8e-153 DegV S EDD domain protein, DegV family
LAPPPKNL_01215 1.2e-109 hlyIII S protein, hemolysin III
LAPPPKNL_01216 8.7e-95 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LAPPPKNL_01217 8e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LAPPPKNL_01218 0.0 yfmR S ABC transporter, ATP-binding protein
LAPPPKNL_01219 2.6e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LAPPPKNL_01220 4.7e-165 xerD L Phage integrase, N-terminal SAM-like domain
LAPPPKNL_01221 6.9e-234 S Tetratricopeptide repeat protein
LAPPPKNL_01222 4.4e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LAPPPKNL_01223 5.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LAPPPKNL_01224 5.8e-209 rpsA 1.17.7.4 J Ribosomal protein S1
LAPPPKNL_01225 5.8e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LAPPPKNL_01226 9.7e-31 M Lysin motif
LAPPPKNL_01227 3.1e-278 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
LAPPPKNL_01228 6e-199 ypbB 5.1.3.1 S Helix-turn-helix domain
LAPPPKNL_01229 4.8e-81 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LAPPPKNL_01230 1.4e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LAPPPKNL_01231 5e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LAPPPKNL_01232 3.9e-142 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LAPPPKNL_01233 5.3e-68 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LAPPPKNL_01234 2.4e-132 xerD D recombinase XerD
LAPPPKNL_01235 1.6e-168 cvfB S S1 domain
LAPPPKNL_01236 8.3e-268 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LAPPPKNL_01237 0.0 dnaE 2.7.7.7 L DNA polymerase
LAPPPKNL_01238 1e-229 XK27_08315 M Sulfatase
LAPPPKNL_01239 2.7e-139 yihY S Belongs to the UPF0761 family
LAPPPKNL_01240 3.8e-31 S Protein of unknown function (DUF2922)
LAPPPKNL_01241 1.3e-07
LAPPPKNL_01242 1.4e-147 recX 2.4.1.337 GT4 S Regulatory protein RecX
LAPPPKNL_01243 1.1e-118 rfbP M Bacterial sugar transferase
LAPPPKNL_01244 1.9e-146 cps1D M Domain of unknown function (DUF4422)
LAPPPKNL_01245 1.9e-95 cps3F
LAPPPKNL_01246 5.9e-45 M biosynthesis protein
LAPPPKNL_01247 2.5e-219 glf 5.4.99.9 M UDP-galactopyranose mutase
LAPPPKNL_01248 1.2e-202 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
LAPPPKNL_01249 2.6e-72 S enterobacterial common antigen metabolic process
LAPPPKNL_01250 1e-61 acmD M repeat protein
LAPPPKNL_01253 2.4e-172 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
LAPPPKNL_01254 1.6e-20 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
LAPPPKNL_01255 1.7e-218 G Transporter, major facilitator family protein
LAPPPKNL_01256 4.4e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LAPPPKNL_01257 2.6e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LAPPPKNL_01258 4.6e-56 ydiI Q Thioesterase superfamily
LAPPPKNL_01259 6.2e-37 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
LAPPPKNL_01260 5.5e-61 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LAPPPKNL_01261 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LAPPPKNL_01262 8.2e-163 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LAPPPKNL_01263 6.1e-13 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
LAPPPKNL_01264 9.4e-135 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LAPPPKNL_01265 3e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LAPPPKNL_01266 6.2e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LAPPPKNL_01267 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LAPPPKNL_01268 5.7e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LAPPPKNL_01269 3.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LAPPPKNL_01270 6e-108 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LAPPPKNL_01271 7.8e-296 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LAPPPKNL_01272 9e-242 purD 6.3.4.13 F Belongs to the GARS family
LAPPPKNL_01273 1.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LAPPPKNL_01274 2.6e-23 S Enoyl-(Acyl carrier protein) reductase
LAPPPKNL_01275 1.9e-172 K Bacterial regulatory helix-turn-helix protein, lysR family
LAPPPKNL_01276 4.4e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
LAPPPKNL_01277 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LAPPPKNL_01278 1.4e-206 carA 6.3.5.5 F Belongs to the CarA family
LAPPPKNL_01279 3.4e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LAPPPKNL_01280 3e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LAPPPKNL_01281 8.3e-70 esbA S Family of unknown function (DUF5322)
LAPPPKNL_01282 3.1e-71 rnhA 3.1.26.4 L Ribonuclease HI
LAPPPKNL_01283 2.8e-108 XK27_02070 S Nitroreductase family
LAPPPKNL_01284 2.3e-156 yckB ET Belongs to the bacterial solute-binding protein 3 family
LAPPPKNL_01285 2.9e-117 yecS E ABC transporter permease
LAPPPKNL_01286 8.4e-22 M Glycosyltransferase like family 2
LAPPPKNL_01287 1.5e-69 dxs 2.2.1.7 HI 1-deoxy-D-xylulose-5-phosphate synthase
LAPPPKNL_01288 4.7e-41 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LAPPPKNL_01289 5.4e-50 ybjQ S Belongs to the UPF0145 family
LAPPPKNL_01290 1.2e-76 rocF 3.5.3.1, 3.5.3.11 E Arginase family
LAPPPKNL_01292 7.9e-174 1.3.1.9 S Nitronate monooxygenase
LAPPPKNL_01293 4.7e-54 K Helix-turn-helix domain
LAPPPKNL_01294 6.2e-105 S Domain of unknown function (DUF4767)
LAPPPKNL_01295 1.4e-77
LAPPPKNL_01296 9.3e-09 S Domain of unknown function (DUF4767)
LAPPPKNL_01297 2e-127 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
LAPPPKNL_01298 1.1e-192 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
LAPPPKNL_01299 2.5e-161 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
LAPPPKNL_01300 0.0 norZ 1.7.2.5 P Cytochrome C and Quinol oxidase polypeptide I
LAPPPKNL_01301 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
LAPPPKNL_01302 6.5e-182 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LAPPPKNL_01303 1.5e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
LAPPPKNL_01304 5e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
LAPPPKNL_01305 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LAPPPKNL_01306 4.7e-39 ptsH G phosphocarrier protein HPR
LAPPPKNL_01308 0.0 clpE O Belongs to the ClpA ClpB family
LAPPPKNL_01309 6.4e-128 3.6.1.13, 3.6.1.55 F NUDIX domain
LAPPPKNL_01310 1.1e-109 pncA Q Isochorismatase family
LAPPPKNL_01311 6.1e-123 bm3R1 K Bacterial regulatory proteins, tetR family
LAPPPKNL_01312 0.0 yhcA V ABC transporter, ATP-binding protein
LAPPPKNL_01313 6.7e-49 S FMN_bind
LAPPPKNL_01314 2e-66 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LAPPPKNL_01315 2.8e-134 P nitric oxide dioxygenase activity
LAPPPKNL_01316 6.8e-49 XK27_08850 S Aminoacyl-tRNA editing domain
LAPPPKNL_01317 5.9e-165 M Membrane
LAPPPKNL_01318 3.4e-23 XK27_06785 V ABC transporter
LAPPPKNL_01319 2.2e-102 K Transcriptional regulator
LAPPPKNL_01320 2.6e-129 K Transcriptional regulatory protein, C-terminal domain protein
LAPPPKNL_01321 5.1e-159 pstS P Phosphate
LAPPPKNL_01322 3.3e-153 pstC P probably responsible for the translocation of the substrate across the membrane
LAPPPKNL_01323 9.4e-153 pstA P Phosphate transport system permease protein PstA
LAPPPKNL_01324 6.8e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LAPPPKNL_01325 1.1e-122 phoU P Plays a role in the regulation of phosphate uptake
LAPPPKNL_01326 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LAPPPKNL_01327 5.4e-40 ylqC S Belongs to the UPF0109 family
LAPPPKNL_01328 2.1e-88 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LAPPPKNL_01329 2.9e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LAPPPKNL_01330 2.2e-260 yfnA E Amino Acid
LAPPPKNL_01331 2.1e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LAPPPKNL_01333 1.2e-141 ET Bacterial periplasmic substrate-binding proteins
LAPPPKNL_01334 2e-110 XK27_05795 P ABC transporter permease
LAPPPKNL_01335 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LAPPPKNL_01336 5.3e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LAPPPKNL_01337 8.6e-159 sufD O Uncharacterized protein family (UPF0051)
LAPPPKNL_01338 5.1e-235 F Permease
LAPPPKNL_01339 3.9e-198 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
LAPPPKNL_01340 2.3e-62 lytE M LysM domain protein
LAPPPKNL_01341 2.7e-117 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
LAPPPKNL_01342 1.8e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LAPPPKNL_01343 5.9e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
LAPPPKNL_01344 3.4e-135 ycsF S LamB/YcsF family
LAPPPKNL_01345 2.7e-211 ycsG P Natural resistance-associated macrophage protein
LAPPPKNL_01346 3.9e-207 EGP Major facilitator Superfamily
LAPPPKNL_01347 2.6e-255 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
LAPPPKNL_01348 1.1e-52 trxA O Belongs to the thioredoxin family
LAPPPKNL_01349 2.2e-152 mleP3 S Membrane transport protein
LAPPPKNL_01351 2.4e-76 cylA V abc transporter atp-binding protein
LAPPPKNL_01352 3.1e-60 cylB V ABC-2 type transporter
LAPPPKNL_01353 7e-27 K LytTr DNA-binding domain
LAPPPKNL_01354 4.8e-11 S Protein of unknown function (DUF3021)
LAPPPKNL_01356 5.1e-89
LAPPPKNL_01357 3.2e-77 F Nucleoside 2-deoxyribosyltransferase
LAPPPKNL_01358 1.8e-181 scrR3 K Transcriptional regulator, LacI family
LAPPPKNL_01359 3e-14
LAPPPKNL_01360 4.9e-17 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
LAPPPKNL_01361 0.0 asnB 6.3.5.4 E Aluminium induced protein
LAPPPKNL_01363 5.1e-146 L Transposase and inactivated derivatives
LAPPPKNL_01364 9.9e-08 S Bacterial transferase hexapeptide (six repeats)
LAPPPKNL_01365 3.9e-119 IQ Enoyl-(Acyl carrier protein) reductase
LAPPPKNL_01366 3.1e-198 gldA 1.1.1.6 C dehydrogenase
LAPPPKNL_01367 3.4e-17 xre K Helix-turn-helix domain
LAPPPKNL_01368 2.1e-51 S Sugar efflux transporter for intercellular exchange
LAPPPKNL_01369 3e-56 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LAPPPKNL_01370 4.6e-45 S Protein conserved in bacteria
LAPPPKNL_01371 3.5e-97 ywrO S Flavodoxin-like fold
LAPPPKNL_01372 9.5e-152 tesE Q hydratase
LAPPPKNL_01373 1.5e-186 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAPPPKNL_01374 2.5e-62 S Domain of unknown function (DUF4440)
LAPPPKNL_01375 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LAPPPKNL_01376 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LAPPPKNL_01377 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LAPPPKNL_01378 8.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LAPPPKNL_01379 1.3e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LAPPPKNL_01380 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LAPPPKNL_01381 3.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LAPPPKNL_01383 8.3e-53 MA20_27270 S mazG nucleotide pyrophosphohydrolase
LAPPPKNL_01384 2.8e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
LAPPPKNL_01385 1.5e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LAPPPKNL_01386 5.7e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LAPPPKNL_01387 4.3e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LAPPPKNL_01388 1.2e-163 S Tetratricopeptide repeat
LAPPPKNL_01389 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LAPPPKNL_01390 2.9e-262 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
LAPPPKNL_01391 4.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LAPPPKNL_01392 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
LAPPPKNL_01393 1.8e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
LAPPPKNL_01394 0.0 comEC S Competence protein ComEC
LAPPPKNL_01395 3.4e-88 comEB 3.5.4.12 F ComE operon protein 2
LAPPPKNL_01396 3.8e-90 comEA L Competence protein ComEA
LAPPPKNL_01397 6.7e-198 ylbL T Belongs to the peptidase S16 family
LAPPPKNL_01398 2.8e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LAPPPKNL_01399 1.3e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
LAPPPKNL_01400 1.4e-47 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
LAPPPKNL_01401 2.8e-216 ftsW D Belongs to the SEDS family
LAPPPKNL_01402 0.0 typA T GTP-binding protein TypA
LAPPPKNL_01403 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
LAPPPKNL_01404 2.4e-49 yktA S Belongs to the UPF0223 family
LAPPPKNL_01405 7.5e-103 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LAPPPKNL_01406 1.5e-74
LAPPPKNL_01407 2.2e-31 ykzG S Belongs to the UPF0356 family
LAPPPKNL_01408 2e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
LAPPPKNL_01409 4.2e-74 spx4 1.20.4.1 P ArsC family
LAPPPKNL_01410 9.4e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LAPPPKNL_01411 0.0 recD 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LAPPPKNL_01412 7.1e-124 S Repeat protein
LAPPPKNL_01413 4.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
LAPPPKNL_01414 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LAPPPKNL_01415 3e-306 S amidohydrolase
LAPPPKNL_01416 5.8e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LAPPPKNL_01417 3.4e-58 XK27_04120 S Putative amino acid metabolism
LAPPPKNL_01418 1.3e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LAPPPKNL_01420 2.7e-97 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
LAPPPKNL_01421 1.2e-32 cspB K Cold shock protein
LAPPPKNL_01422 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LAPPPKNL_01424 4.8e-112 divIVA D DivIVA domain protein
LAPPPKNL_01425 1.3e-145 ylmH S S4 domain protein
LAPPPKNL_01426 6.8e-41 yggT S YGGT family
LAPPPKNL_01427 2.7e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LAPPPKNL_01428 9e-221 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LAPPPKNL_01429 2.7e-223 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LAPPPKNL_01430 8.4e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LAPPPKNL_01431 2.8e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LAPPPKNL_01432 2.8e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LAPPPKNL_01433 9.1e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LAPPPKNL_01434 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LAPPPKNL_01435 7e-09 ftsL D Cell division protein FtsL
LAPPPKNL_01436 1.1e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LAPPPKNL_01437 5.6e-79 mraZ K Belongs to the MraZ family
LAPPPKNL_01438 5.8e-58
LAPPPKNL_01439 1.2e-07 S Protein of unknown function (DUF4044)
LAPPPKNL_01440 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LAPPPKNL_01441 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LAPPPKNL_01442 2.2e-162 rrmA 2.1.1.187 H Methyltransferase
LAPPPKNL_01443 1.4e-195 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
LAPPPKNL_01444 8.2e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
LAPPPKNL_01445 1e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LAPPPKNL_01446 6e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
LAPPPKNL_01447 1e-113 yjbH Q Thioredoxin
LAPPPKNL_01448 3.2e-205 coiA 3.6.4.12 S Competence protein
LAPPPKNL_01449 5.3e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LAPPPKNL_01450 1.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LAPPPKNL_01451 6e-16 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LAPPPKNL_01456 6.1e-88 3.5.1.4, 6.3.5.6, 6.3.5.7 J Amidase
LAPPPKNL_01457 2.8e-151 pucI FH Permease for cytosine/purines, uracil, thiamine, allantoin
LAPPPKNL_01458 1.1e-166 allB 3.5.2.5 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LAPPPKNL_01459 5.1e-133 pucR QT Purine catabolism regulatory protein-like family
LAPPPKNL_01460 4.2e-135 3.5.1.6, 3.5.1.87, 3.5.3.9 E Peptidase family M20/M25/M40
LAPPPKNL_01461 1.4e-178 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
LAPPPKNL_01462 4.8e-145 L 4.5 Transposon and IS
LAPPPKNL_01463 1.3e-28 L Transposase
LAPPPKNL_01464 3.1e-124 S Membrane
LAPPPKNL_01465 5.4e-234 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LAPPPKNL_01466 0.0 pepF E oligoendopeptidase F
LAPPPKNL_01467 1e-163 K helix_turn _helix lactose operon repressor
LAPPPKNL_01468 2.7e-140 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LAPPPKNL_01469 8.7e-78 K AsnC family
LAPPPKNL_01470 1e-81 uspA T universal stress protein
LAPPPKNL_01471 0.0 cas3 L CRISPR-associated helicase cas3
LAPPPKNL_01472 7.8e-297 casA L the current gene model (or a revised gene model) may contain a frame shift
LAPPPKNL_01473 3e-102 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
LAPPPKNL_01474 1.4e-195 casC L CT1975-like protein
LAPPPKNL_01475 1.1e-132 casD S CRISPR-associated protein (Cas_Cas5)
LAPPPKNL_01476 5.6e-110 casE S CRISPR_assoc
LAPPPKNL_01477 2e-135 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LAPPPKNL_01478 2.1e-131 czcD P cation diffusion facilitator family transporter
LAPPPKNL_01479 4.5e-133 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 L Psort location Cytoplasmic, score
LAPPPKNL_01480 9.7e-13
LAPPPKNL_01481 1.2e-305 traI 5.99.1.2 L C-terminal repeat of topoisomerase
LAPPPKNL_01482 4e-23
LAPPPKNL_01483 3.4e-75
LAPPPKNL_01484 5.7e-07
LAPPPKNL_01485 1e-220 traK U TraM recognition site of TraD and TraG
LAPPPKNL_01486 1.7e-44
LAPPPKNL_01487 4.3e-242 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LAPPPKNL_01488 2.3e-241 yfnA E amino acid
LAPPPKNL_01489 3.2e-83 S NADPH-dependent FMN reductase
LAPPPKNL_01491 1.3e-156 L Thioesterase-like superfamily
LAPPPKNL_01492 3.1e-50 lacA S transferase hexapeptide repeat
LAPPPKNL_01493 6.2e-260 argH 4.3.2.1 E argininosuccinate lyase
LAPPPKNL_01494 4.7e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LAPPPKNL_01495 2.4e-184 hoxN U High-affinity nickel-transport protein
LAPPPKNL_01496 5.9e-149 larE S NAD synthase
LAPPPKNL_01497 4.5e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
LAPPPKNL_01498 2.4e-216 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LAPPPKNL_01499 1.7e-131 cpmA S AIR carboxylase
LAPPPKNL_01500 3.6e-241 larA 5.1.2.1 S Domain of unknown function (DUF2088)
LAPPPKNL_01501 7e-124 K Crp-like helix-turn-helix domain
LAPPPKNL_01502 3.6e-143 L Transposase and inactivated derivatives, IS30 family
LAPPPKNL_01503 9.2e-253 G Major Facilitator
LAPPPKNL_01504 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
LAPPPKNL_01505 9.4e-178 K Transcriptional regulator, LacI family
LAPPPKNL_01506 3.7e-158 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
LAPPPKNL_01507 4.6e-09
LAPPPKNL_01508 2.7e-224 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
LAPPPKNL_01510 6.9e-47
LAPPPKNL_01511 3.2e-273 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
LAPPPKNL_01512 6e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
LAPPPKNL_01513 1e-148 metQ1 P Belongs to the nlpA lipoprotein family
LAPPPKNL_01514 7.2e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LAPPPKNL_01515 1.2e-97 metI P ABC transporter permease
LAPPPKNL_01516 4.4e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
LAPPPKNL_01517 7.4e-11 yicL EG EamA-like transporter family
LAPPPKNL_01518 2.6e-74 S Domain of unknown function (DUF4352)
LAPPPKNL_01519 0.0 1.3.5.4 C FAD binding domain
LAPPPKNL_01520 5.7e-169 K LysR substrate binding domain
LAPPPKNL_01521 4.1e-161 rssA S Phospholipase, patatin family
LAPPPKNL_01522 1.7e-213 phbA 2.3.1.9 I Belongs to the thiolase family
LAPPPKNL_01523 1.9e-179 S AI-2E family transporter
LAPPPKNL_01524 7.1e-20 S membrane transporter protein
LAPPPKNL_01525 6.6e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LAPPPKNL_01526 1.1e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LAPPPKNL_01527 1e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LAPPPKNL_01528 0.0 asnB 6.3.5.4 E Asparagine synthase
LAPPPKNL_01529 6.6e-220 lysP E amino acid
LAPPPKNL_01530 2.1e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LAPPPKNL_01531 1.6e-85 ykhA 3.1.2.20 I Thioesterase superfamily
LAPPPKNL_01532 1.1e-77 hsp O Belongs to the small heat shock protein (HSP20) family
LAPPPKNL_01533 4.1e-111 K Transcriptional regulator, TetR family
LAPPPKNL_01535 4e-22
LAPPPKNL_01536 4.1e-248 cycA E Amino acid permease
LAPPPKNL_01537 7.4e-85 perR P Belongs to the Fur family
LAPPPKNL_01538 1.4e-254 EGP Major facilitator Superfamily
LAPPPKNL_01539 4.4e-97 tag 3.2.2.20 L glycosylase
LAPPPKNL_01540 5e-51
LAPPPKNL_01541 3e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LAPPPKNL_01542 3.7e-140 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LAPPPKNL_01543 1.1e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LAPPPKNL_01544 7.8e-126 3.1.3.2, 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I Acid phosphatase homologues
LAPPPKNL_01545 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LAPPPKNL_01546 2.6e-42
LAPPPKNL_01547 4.7e-299 ytgP S Polysaccharide biosynthesis protein
LAPPPKNL_01548 1.6e-61 3.2.1.23 S Domain of unknown function DUF302
LAPPPKNL_01549 1.9e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LAPPPKNL_01550 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
LAPPPKNL_01551 1.2e-85 uspA T Belongs to the universal stress protein A family
LAPPPKNL_01552 3.5e-255 S Putative peptidoglycan binding domain
LAPPPKNL_01553 9.7e-163 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LAPPPKNL_01554 8.6e-116 dck 2.7.1.74 F deoxynucleoside kinase
LAPPPKNL_01555 3.6e-111
LAPPPKNL_01556 9.9e-183 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
LAPPPKNL_01557 1.1e-119 S CAAX protease self-immunity
LAPPPKNL_01558 2.5e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LAPPPKNL_01559 1.3e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
LAPPPKNL_01560 1.5e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
LAPPPKNL_01561 3.7e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LAPPPKNL_01562 2.6e-106 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
LAPPPKNL_01563 2e-200 folP 2.5.1.15 H dihydropteroate synthase
LAPPPKNL_01565 1.7e-36
LAPPPKNL_01567 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LAPPPKNL_01568 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LAPPPKNL_01569 9.8e-56 yheA S Belongs to the UPF0342 family
LAPPPKNL_01570 5.7e-180 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
LAPPPKNL_01571 3.1e-149 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LAPPPKNL_01573 1.4e-77 hit FG histidine triad
LAPPPKNL_01574 2.3e-133 ecsA V ABC transporter, ATP-binding protein
LAPPPKNL_01575 2.9e-210 ecsB U ABC transporter
LAPPPKNL_01576 1.8e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LAPPPKNL_01577 3.3e-58 ytzB S Small secreted protein
LAPPPKNL_01578 6.5e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LAPPPKNL_01579 7.8e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LAPPPKNL_01580 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LAPPPKNL_01581 4e-114 ybhL S Belongs to the BI1 family
LAPPPKNL_01582 5e-139 aroD S Serine hydrolase (FSH1)
LAPPPKNL_01583 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LAPPPKNL_01584 2.1e-162 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LAPPPKNL_01585 3.9e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LAPPPKNL_01586 8.5e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LAPPPKNL_01587 3.6e-252 dnaB L replication initiation and membrane attachment
LAPPPKNL_01588 2.1e-171 dnaI L Primosomal protein DnaI
LAPPPKNL_01589 1.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LAPPPKNL_01590 1.5e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LAPPPKNL_01591 6.6e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LAPPPKNL_01592 1.9e-19 yoaK S Protein of unknown function (DUF1275)
LAPPPKNL_01593 1.6e-25 yoaK S Protein of unknown function (DUF1275)
LAPPPKNL_01594 2.2e-96 yqeG S HAD phosphatase, family IIIA
LAPPPKNL_01595 7.6e-216 yqeH S Ribosome biogenesis GTPase YqeH
LAPPPKNL_01596 2.6e-49 yhbY J RNA-binding protein
LAPPPKNL_01597 4.1e-94 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LAPPPKNL_01598 7.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
LAPPPKNL_01599 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LAPPPKNL_01600 4.5e-140 yqeM Q Methyltransferase
LAPPPKNL_01601 1.7e-215 ylbM S Belongs to the UPF0348 family
LAPPPKNL_01602 1.2e-97 yceD S Uncharacterized ACR, COG1399
LAPPPKNL_01603 7.2e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LAPPPKNL_01604 5.6e-121 K response regulator
LAPPPKNL_01605 7.6e-280 arlS 2.7.13.3 T Histidine kinase
LAPPPKNL_01606 1.6e-233 V MatE
LAPPPKNL_01607 3e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LAPPPKNL_01608 7.2e-132 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LAPPPKNL_01609 4.1e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LAPPPKNL_01610 1.2e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LAPPPKNL_01611 7.8e-91 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
LAPPPKNL_01612 7.8e-60 yodB K Transcriptional regulator, HxlR family
LAPPPKNL_01613 5.1e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LAPPPKNL_01614 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LAPPPKNL_01615 3e-116 udk 2.7.1.48 F Cytidine monophosphokinase
LAPPPKNL_01616 2.2e-79 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LAPPPKNL_01617 0.0 S membrane
LAPPPKNL_01618 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
LAPPPKNL_01619 3.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LAPPPKNL_01620 9.2e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LAPPPKNL_01621 1.1e-116 gluP 3.4.21.105 S Peptidase, S54 family
LAPPPKNL_01622 9.6e-36 yqgQ S Bacterial protein of unknown function (DUF910)
LAPPPKNL_01623 1.2e-180 glk 2.7.1.2 G Glucokinase
LAPPPKNL_01624 1.5e-71 yqhL P Rhodanese-like protein
LAPPPKNL_01625 4.8e-24 WQ51_02665 S Protein of unknown function (DUF3042)
LAPPPKNL_01626 3.2e-172 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LAPPPKNL_01627 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
LAPPPKNL_01628 4.7e-13
LAPPPKNL_01629 2.4e-148
LAPPPKNL_01630 1.1e-175
LAPPPKNL_01631 1.5e-92 dut S Protein conserved in bacteria
LAPPPKNL_01632 1.5e-200 S Phage integrase family
LAPPPKNL_01635 7.8e-54
LAPPPKNL_01636 1.6e-17 L nuclease
LAPPPKNL_01637 2.7e-43 kcsA P Ion transport protein
LAPPPKNL_01639 9.5e-217 M Glycosyl transferase family group 2
LAPPPKNL_01641 1.3e-172 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LAPPPKNL_01642 1.1e-64 S Initiator Replication protein
LAPPPKNL_01644 2.4e-51 L Resolvase, N terminal domain
LAPPPKNL_01645 1e-212 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LAPPPKNL_01646 4.8e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LAPPPKNL_01647 2.5e-40 gcvR T Belongs to the UPF0237 family
LAPPPKNL_01648 2.1e-244 XK27_08635 S UPF0210 protein
LAPPPKNL_01649 4e-178 yobV1 K WYL domain
LAPPPKNL_01650 2.1e-67 S pyridoxamine 5-phosphate
LAPPPKNL_01651 5.7e-35
LAPPPKNL_01654 2.3e-53 S Mazg nucleotide pyrophosphohydrolase
LAPPPKNL_01655 4.6e-137 E GDSL-like Lipase/Acylhydrolase family
LAPPPKNL_01656 8.8e-124 C nitroreductase
LAPPPKNL_01657 1.3e-176 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
LAPPPKNL_01658 1.3e-120 arcC 2.7.2.2 E Amino acid kinase family
LAPPPKNL_01661 7.3e-41 sucD 6.2.1.5 C Protein of unknown function (DUF1116)
LAPPPKNL_01662 2.1e-65 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
LAPPPKNL_01663 3.9e-25 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
LAPPPKNL_01664 5e-38 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E Aminotransferase class-V
LAPPPKNL_01665 2.6e-180 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAPPPKNL_01667 8.6e-11 S YjcQ protein
LAPPPKNL_01668 2.5e-147 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAPPPKNL_01669 5.3e-133 S Membrane
LAPPPKNL_01670 1.3e-75 4.4.1.5 E Glyoxalase
LAPPPKNL_01671 4.5e-85 yueI S Protein of unknown function (DUF1694)
LAPPPKNL_01672 5.8e-236 rarA L recombination factor protein RarA
LAPPPKNL_01674 2.3e-81 usp6 T universal stress protein
LAPPPKNL_01675 2.9e-151 2.3.1.19 K Helix-turn-helix XRE-family like proteins
LAPPPKNL_01676 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
LAPPPKNL_01677 1.3e-254 G Major Facilitator Superfamily
LAPPPKNL_01678 1.3e-130 tnp L DDE domain
LAPPPKNL_01679 9.6e-234 yagE E Amino acid permease
LAPPPKNL_01680 8.3e-216 S Domain of unknown function (DUF389)
LAPPPKNL_01681 1.4e-53
LAPPPKNL_01682 1.5e-102 hrtB V ABC transporter permease
LAPPPKNL_01683 4.5e-115 devA 3.6.3.25 V ABC transporter, ATP-binding protein
LAPPPKNL_01684 4.5e-103 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
LAPPPKNL_01686 1.6e-122 3.6.1.3 S AAA domain
LAPPPKNL_01687 2.3e-212 L Mu transposase, C-terminal
LAPPPKNL_01688 3.1e-85 tnpR2 L Resolvase, N terminal domain
LAPPPKNL_01691 2.9e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LAPPPKNL_01692 2.2e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LAPPPKNL_01693 1e-66 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LAPPPKNL_01694 1.1e-103 wecD3 K Acetyltransferase (GNAT) family
LAPPPKNL_01695 2.4e-311 ubiB S ABC1 family
LAPPPKNL_01696 2.3e-130 1.14.12.17 C Oxidoreductase NAD-binding domain
LAPPPKNL_01697 1.7e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
LAPPPKNL_01698 2.8e-177
LAPPPKNL_01699 6.5e-47 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LAPPPKNL_01700 5e-53 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
LAPPPKNL_01701 0.0 copA 3.6.3.54 P P-type ATPase
LAPPPKNL_01702 6e-26 EGP Major facilitator Superfamily
LAPPPKNL_01703 4.7e-90 2.4.2.6 F nucleoside 2-deoxyribosyltransferase
LAPPPKNL_01704 1.7e-13 dtpT U amino acid peptide transporter
LAPPPKNL_01705 2.5e-178 dtpT U amino acid peptide transporter
LAPPPKNL_01706 7.8e-110 GK ROK family
LAPPPKNL_01707 8.5e-50 copY K Copper transport repressor CopY TcrY
LAPPPKNL_01708 7.6e-11 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LAPPPKNL_01709 5.5e-96 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
LAPPPKNL_01710 2.6e-148 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LAPPPKNL_01711 6.9e-123 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LAPPPKNL_01712 5.5e-225 aadAT EK Aminotransferase, class I
LAPPPKNL_01713 6.1e-159 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
LAPPPKNL_01714 6.3e-143 ET Bacterial periplasmic substrate-binding proteins
LAPPPKNL_01715 8.9e-217 I transferase activity, transferring acyl groups other than amino-acyl groups
LAPPPKNL_01717 2.6e-245 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LAPPPKNL_01718 3.7e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LAPPPKNL_01719 4.4e-198 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LAPPPKNL_01720 0.0 smc D Required for chromosome condensation and partitioning
LAPPPKNL_01721 5.2e-130 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LAPPPKNL_01722 4.5e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAPPPKNL_01723 2.8e-164 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LAPPPKNL_01724 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LAPPPKNL_01725 2.9e-304 yloV S DAK2 domain fusion protein YloV
LAPPPKNL_01726 3.6e-58 asp S Asp23 family, cell envelope-related function
LAPPPKNL_01727 7.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LAPPPKNL_01728 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
LAPPPKNL_01729 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LAPPPKNL_01730 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LAPPPKNL_01731 0.0 KLT serine threonine protein kinase
LAPPPKNL_01732 2.2e-131 stp 3.1.3.16 T phosphatase
LAPPPKNL_01733 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LAPPPKNL_01734 2.7e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LAPPPKNL_01735 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LAPPPKNL_01736 2.7e-214 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LAPPPKNL_01737 3.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LAPPPKNL_01738 3.9e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LAPPPKNL_01739 2.5e-15
LAPPPKNL_01740 1.3e-307 recN L May be involved in recombinational repair of damaged DNA
LAPPPKNL_01741 2.3e-75 argR K Regulates arginine biosynthesis genes
LAPPPKNL_01742 6.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LAPPPKNL_01743 6.2e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LAPPPKNL_01744 1e-18 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LAPPPKNL_01745 8.7e-257 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LAPPPKNL_01746 2.6e-160 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LAPPPKNL_01747 4e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LAPPPKNL_01748 4.1e-72 yqhY S Asp23 family, cell envelope-related function
LAPPPKNL_01749 3.1e-206 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
LAPPPKNL_01750 7.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LAPPPKNL_01751 9e-53 ysxB J Cysteine protease Prp
LAPPPKNL_01752 8.9e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
LAPPPKNL_01753 2.8e-114 K Transcriptional regulator
LAPPPKNL_01755 1.8e-10
LAPPPKNL_01756 5.3e-27
LAPPPKNL_01757 6.9e-92 ps461 3.5.1.104 M hydrolase, family 25
LAPPPKNL_01758 6.8e-19 S Bacteriophage holin of superfamily 6 (Holin_LLH)
LAPPPKNL_01762 2e-59
LAPPPKNL_01763 2.6e-27 S GDSL-like Lipase/Acylhydrolase
LAPPPKNL_01766 2.6e-58 spoIVFA GT2,GT4 D peptidase
LAPPPKNL_01767 6.9e-114 S Peptidase family M23
LAPPPKNL_01768 4.9e-151 S Phage tail protein
LAPPPKNL_01769 0.0 S peptidoglycan catabolic process
LAPPPKNL_01770 9.9e-14
LAPPPKNL_01771 1.7e-12
LAPPPKNL_01772 1.2e-111 S Pfam:Phage_TTP_1
LAPPPKNL_01773 4.5e-41
LAPPPKNL_01774 3.7e-37 S Bacteriophage HK97-gp10, putative tail-component
LAPPPKNL_01775 1.3e-30 S Phage head-tail joining protein
LAPPPKNL_01776 1.1e-44 S Phage gp6-like head-tail connector protein
LAPPPKNL_01777 4e-193 S peptidase activity
LAPPPKNL_01778 6e-40 pi136 S Caudovirus prohead serine protease
LAPPPKNL_01779 1.6e-238 S Phage portal protein
LAPPPKNL_01781 0.0 S Phage Terminase
LAPPPKNL_01782 1.1e-77 S Phage terminase, small subunit
LAPPPKNL_01783 5.6e-149 S HNH endonuclease
LAPPPKNL_01784 2.5e-154 S DNA metabolic process
LAPPPKNL_01787 1e-08 S Domain of unknown function (DUF771)
LAPPPKNL_01792 1.4e-144 K Phage regulatory protein
LAPPPKNL_01793 3.3e-47 3.4.21.88 K Helix-turn-helix domain
LAPPPKNL_01794 4.7e-67
LAPPPKNL_01795 7.6e-44 2.7.11.1 NU Domain of unknown function (DUF5067)
LAPPPKNL_01798 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
LAPPPKNL_01799 4.5e-120 V Type I restriction modification DNA specificity domain
LAPPPKNL_01800 2.7e-73 IQ reductase
LAPPPKNL_01801 2e-240 treB G phosphotransferase system
LAPPPKNL_01802 1.5e-71 treR K UTRA
LAPPPKNL_01803 2.9e-240 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
LAPPPKNL_01804 3.7e-221 iscS 2.8.1.7 E Aminotransferase class V
LAPPPKNL_01805 2.3e-16 S ABC-type transport system involved in multi-copper enzyme maturation permease component
LAPPPKNL_01806 2e-52 T Transcriptional regulatory protein, C terminal
LAPPPKNL_01807 5.2e-62 T His Kinase A (phosphoacceptor) domain
LAPPPKNL_01808 2.5e-54 C FMN binding
LAPPPKNL_01809 8.4e-37 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LAPPPKNL_01810 2.8e-282 ysaB V FtsX-like permease family
LAPPPKNL_01811 7.1e-117 macB2 V ABC transporter, ATP-binding protein
LAPPPKNL_01812 3.7e-105 T Histidine kinase-like ATPases
LAPPPKNL_01813 5.6e-97 K response regulator
LAPPPKNL_01814 1.7e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LAPPPKNL_01815 7e-155 tesE Q hydratase
LAPPPKNL_01816 1.8e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
LAPPPKNL_01817 4.7e-48 L transposase, IS605 OrfB family
LAPPPKNL_01818 1e-38 mdt(A) EGP Major facilitator Superfamily
LAPPPKNL_01819 6.5e-75 K Copper transport repressor CopY TcrY
LAPPPKNL_01820 0.0 copB 3.6.3.4 P P-type ATPase
LAPPPKNL_01822 1.2e-196 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
LAPPPKNL_01823 0.0 scrA 2.7.1.211, 5.3.1.1 G phosphotransferase system
LAPPPKNL_01824 1e-107 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LAPPPKNL_01825 9.3e-253 nox C NADH oxidase
LAPPPKNL_01826 1.2e-260 npr 1.11.1.1 C NADH oxidase
LAPPPKNL_01827 2e-58 S hydrolase
LAPPPKNL_01828 8.3e-254 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
LAPPPKNL_01829 2.7e-239 cycA E Amino acid permease
LAPPPKNL_01830 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LAPPPKNL_01831 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LAPPPKNL_01832 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LAPPPKNL_01833 1.4e-186 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LAPPPKNL_01834 6.4e-156 recO L Involved in DNA repair and RecF pathway recombination
LAPPPKNL_01835 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LAPPPKNL_01836 1e-66 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LAPPPKNL_01837 5.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LAPPPKNL_01838 1.1e-178 phoH T phosphate starvation-inducible protein PhoH
LAPPPKNL_01839 4.6e-71 yqeY S YqeY-like protein
LAPPPKNL_01840 5.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LAPPPKNL_01841 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
LAPPPKNL_01842 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LAPPPKNL_01843 1e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
LAPPPKNL_01844 2.1e-196 6.3.1.20 H Lipoate-protein ligase
LAPPPKNL_01845 1.6e-174 lytH 3.5.1.28 M Ami_3
LAPPPKNL_01846 1.4e-169 yniA G Phosphotransferase enzyme family
LAPPPKNL_01847 3.9e-173 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
LAPPPKNL_01848 1.4e-246 mmuP E amino acid
LAPPPKNL_01849 3.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
LAPPPKNL_01850 1.4e-212 hom1 1.1.1.3 E Homoserine dehydrogenase
LAPPPKNL_01852 2.7e-137 IQ KR domain
LAPPPKNL_01853 3.1e-153 cjaA ET ABC transporter substrate-binding protein
LAPPPKNL_01854 3.9e-136 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
LAPPPKNL_01855 8.5e-114 P ABC transporter permease
LAPPPKNL_01856 5.4e-113 papP P ABC transporter, permease protein
LAPPPKNL_01858 3.2e-150 ET Bacterial periplasmic substrate-binding proteins
LAPPPKNL_01859 7.3e-108 yxeN U ABC transporter, permease protein
LAPPPKNL_01860 1.8e-71 P Binding-protein-dependent transport system inner membrane component
LAPPPKNL_01861 2.2e-134 tcyN 3.6.3.21 E ABC transporter
LAPPPKNL_01862 6.4e-198 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
LAPPPKNL_01863 6.2e-210 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
LAPPPKNL_01864 4.6e-219 metC1 2.5.1.48, 4.4.1.8 E cystathionine
LAPPPKNL_01865 1e-84 slyA K Transcriptional regulator
LAPPPKNL_01866 2.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LAPPPKNL_01867 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LAPPPKNL_01868 9.8e-58
LAPPPKNL_01869 2e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LAPPPKNL_01870 1.8e-181 prmA J Ribosomal protein L11 methyltransferase
LAPPPKNL_01871 1.2e-54
LAPPPKNL_01873 5.2e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LAPPPKNL_01874 6e-39 S integral membrane protein
LAPPPKNL_01875 1.1e-40 S integral membrane protein
LAPPPKNL_01876 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LAPPPKNL_01877 2.1e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LAPPPKNL_01878 7.9e-143 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LAPPPKNL_01879 2.4e-113 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LAPPPKNL_01880 1.5e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LAPPPKNL_01881 4.2e-69 psiE S Phosphate-starvation-inducible E
LAPPPKNL_01882 1e-38 V CAAX protease self-immunity
LAPPPKNL_01883 1.9e-216 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
LAPPPKNL_01884 1.6e-94 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
LAPPPKNL_01885 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
LAPPPKNL_01886 1.7e-159 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
LAPPPKNL_01887 3.5e-76 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
LAPPPKNL_01888 2.3e-106 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
LAPPPKNL_01889 3.6e-09 K LysR substrate binding domain
LAPPPKNL_01890 4.7e-09 S ChrR Cupin-like domain
LAPPPKNL_01891 1.5e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LAPPPKNL_01892 1.9e-158 P Belongs to the nlpA lipoprotein family
LAPPPKNL_01893 8.4e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LAPPPKNL_01894 3.2e-116 S Protein of unknown function (DUF554)
LAPPPKNL_01895 1.1e-101 P Cadmium resistance transporter
LAPPPKNL_01896 3e-75 gtcA S Teichoic acid glycosylation protein
LAPPPKNL_01897 1.2e-76 fld C Flavodoxin
LAPPPKNL_01898 5.9e-168 map 3.4.11.18 E Methionine Aminopeptidase
LAPPPKNL_01899 1.3e-279 XK27_08315 M Sulfatase
LAPPPKNL_01900 3.8e-16
LAPPPKNL_01901 6e-12 S Transglycosylase associated protein
LAPPPKNL_01902 1e-69 S Asp23 family, cell envelope-related function
LAPPPKNL_01903 1.3e-86
LAPPPKNL_01904 1.3e-38 L Transposase and inactivated derivatives
LAPPPKNL_01905 1.1e-153 L COG2801 Transposase and inactivated derivatives
LAPPPKNL_01906 3.6e-210 L Belongs to the 'phage' integrase family
LAPPPKNL_01907 7.3e-35
LAPPPKNL_01909 7.5e-67 S Domain of unknown function DUF1828
LAPPPKNL_01910 2.2e-26
LAPPPKNL_01911 4.8e-295 scrB 3.2.1.26 GH32 G invertase
LAPPPKNL_01912 1.6e-260 S Uncharacterized protein conserved in bacteria (DUF2252)
LAPPPKNL_01914 3.1e-44 S Protein of unknown function with HXXEE motif
LAPPPKNL_01915 5.4e-11 K Bacterial regulatory proteins, tetR family
LAPPPKNL_01916 4.6e-25
LAPPPKNL_01917 6.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
LAPPPKNL_01918 0.0 trxB2 1.8.1.9 C Thioredoxin domain
LAPPPKNL_01919 4.8e-66 kilA K BRO family, N-terminal domain
LAPPPKNL_01920 9e-10 S sequence-specific DNA binding
LAPPPKNL_01921 4.4e-64 3.4.21.88 K Peptidase S24-like
LAPPPKNL_01922 3.7e-13
LAPPPKNL_01923 1.4e-63 pglK S polysaccharide biosynthetic process
LAPPPKNL_01924 3e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LAPPPKNL_01925 4.9e-52 ypaA S Protein of unknown function (DUF1304)
LAPPPKNL_01926 2.1e-26 D Alpha beta
LAPPPKNL_01928 8.2e-34 S Protein of unknown function (DUF1064)
LAPPPKNL_01929 4.4e-10 K Cro/C1-type HTH DNA-binding domain
LAPPPKNL_01931 7.8e-45 dnaC 3.4.21.53 L IstB-like ATP binding protein
LAPPPKNL_01934 7.4e-65 sdaAB 4.3.1.17 E Serine dehydratase beta chain
LAPPPKNL_01935 2.1e-91 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LAPPPKNL_01936 2e-25 yitW S Iron-sulfur cluster assembly protein
LAPPPKNL_01937 2.9e-08 Q Signal peptide protein, YSIRK family
LAPPPKNL_01938 7.3e-45 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LAPPPKNL_01939 8.5e-58 UW LPXTG-motif cell wall anchor domain protein
LAPPPKNL_01940 1.1e-43 UW LPXTG-motif cell wall anchor domain protein
LAPPPKNL_01941 1.7e-86 yrjD S LUD domain
LAPPPKNL_01942 1.3e-242 lutB C 4Fe-4S dicluster domain
LAPPPKNL_01943 1.6e-118 lutA C Cysteine-rich domain
LAPPPKNL_01944 1.6e-216 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
LAPPPKNL_01945 4.2e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LAPPPKNL_01946 2.4e-37 ynzC S UPF0291 protein
LAPPPKNL_01947 2.7e-27 yneF S Uncharacterised protein family (UPF0154)
LAPPPKNL_01948 3.3e-115 plsC 2.3.1.51 I Acyltransferase
LAPPPKNL_01949 8e-137 yabB 2.1.1.223 L Methyltransferase small domain
LAPPPKNL_01950 5.1e-47 yazA L GIY-YIG catalytic domain protein
LAPPPKNL_01951 5e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
LAPPPKNL_01952 4.9e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LAPPPKNL_01953 1.6e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LAPPPKNL_01954 1.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LAPPPKNL_01955 1.3e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LAPPPKNL_01956 2.3e-134 cdsA 2.7.7.41 I Belongs to the CDS family
LAPPPKNL_01957 4.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LAPPPKNL_01958 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LAPPPKNL_01959 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LAPPPKNL_01960 5.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
LAPPPKNL_01961 4.7e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
LAPPPKNL_01962 1.2e-206 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LAPPPKNL_01963 3.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LAPPPKNL_01964 2.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LAPPPKNL_01965 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
LAPPPKNL_01966 3.3e-83 rimP J Required for maturation of 30S ribosomal subunits
LAPPPKNL_01967 3.7e-224 nusA K Participates in both transcription termination and antitermination
LAPPPKNL_01968 1.4e-47 ylxR K Protein of unknown function (DUF448)
LAPPPKNL_01969 3.2e-50 ylxQ J ribosomal protein
LAPPPKNL_01970 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LAPPPKNL_01971 4.2e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LAPPPKNL_01972 6.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LAPPPKNL_01973 6e-185 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LAPPPKNL_01974 6.4e-249 EGP Major facilitator Superfamily
LAPPPKNL_01976 4.7e-09
LAPPPKNL_01979 2.1e-148 recT L RecT family
LAPPPKNL_01980 1e-82 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
LAPPPKNL_01981 2.8e-12 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LAPPPKNL_01988 1.4e-07 K Bacterial regulatory proteins, tetR family
LAPPPKNL_01990 1e-11 qacC P COG2076 Membrane transporters of cations and cationic drugs
LAPPPKNL_01991 2.8e-292 norB EGP Major Facilitator
LAPPPKNL_01994 2.3e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LAPPPKNL_01995 1.6e-134 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
LAPPPKNL_01996 2.3e-72 K helix_turn_helix, mercury resistance
LAPPPKNL_01997 3e-78
LAPPPKNL_01998 4.1e-110
LAPPPKNL_01999 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)