ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMGFFLMG_00001 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMGFFLMG_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMGFFLMG_00003 2.4e-33 yaaA S S4 domain
HMGFFLMG_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMGFFLMG_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
HMGFFLMG_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMGFFLMG_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMGFFLMG_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
HMGFFLMG_00011 2.7e-182 yaaC S YaaC-like Protein
HMGFFLMG_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HMGFFLMG_00013 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMGFFLMG_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HMGFFLMG_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HMGFFLMG_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMGFFLMG_00017 1.3e-09
HMGFFLMG_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HMGFFLMG_00019 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HMGFFLMG_00020 5.6e-215 yaaH M Glycoside Hydrolase Family
HMGFFLMG_00021 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
HMGFFLMG_00022 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMGFFLMG_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMGFFLMG_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMGFFLMG_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMGFFLMG_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HMGFFLMG_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HMGFFLMG_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
HMGFFLMG_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
HMGFFLMG_00032 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HMGFFLMG_00033 4.5e-203 yaaN P Belongs to the TelA family
HMGFFLMG_00034 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HMGFFLMG_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMGFFLMG_00036 2.2e-54 yaaQ S protein conserved in bacteria
HMGFFLMG_00037 1.5e-71 yaaR S protein conserved in bacteria
HMGFFLMG_00038 2.2e-182 holB 2.7.7.7 L DNA polymerase III
HMGFFLMG_00039 2.1e-146 yaaT S stage 0 sporulation protein
HMGFFLMG_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
HMGFFLMG_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HMGFFLMG_00042 1.5e-49 yazA L endonuclease containing a URI domain
HMGFFLMG_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMGFFLMG_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HMGFFLMG_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMGFFLMG_00046 1.8e-144 tatD L hydrolase, TatD
HMGFFLMG_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
HMGFFLMG_00048 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMGFFLMG_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMGFFLMG_00050 3.3e-137 yabG S peptidase
HMGFFLMG_00051 7.8e-39 veg S protein conserved in bacteria
HMGFFLMG_00052 8.3e-27 sspF S DNA topological change
HMGFFLMG_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMGFFLMG_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HMGFFLMG_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HMGFFLMG_00056 1e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HMGFFLMG_00057 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMGFFLMG_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMGFFLMG_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HMGFFLMG_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMGFFLMG_00061 2.4e-39 yabK S Peptide ABC transporter permease
HMGFFLMG_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMGFFLMG_00063 1.5e-92 spoVT K stage V sporulation protein
HMGFFLMG_00064 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMGFFLMG_00065 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HMGFFLMG_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HMGFFLMG_00067 1.5e-49 yabP S Sporulation protein YabP
HMGFFLMG_00068 3.9e-108 yabQ S spore cortex biosynthesis protein
HMGFFLMG_00069 1.1e-44 divIC D Septum formation initiator
HMGFFLMG_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HMGFFLMG_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HMGFFLMG_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HMGFFLMG_00075 6.7e-187 KLT serine threonine protein kinase
HMGFFLMG_00076 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMGFFLMG_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMGFFLMG_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMGFFLMG_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HMGFFLMG_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMGFFLMG_00081 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HMGFFLMG_00082 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMGFFLMG_00083 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMGFFLMG_00084 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HMGFFLMG_00085 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HMGFFLMG_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HMGFFLMG_00087 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMGFFLMG_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HMGFFLMG_00089 4.1e-30 yazB K transcriptional
HMGFFLMG_00090 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMGFFLMG_00091 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMGFFLMG_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
HMGFFLMG_00097 2e-08
HMGFFLMG_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
HMGFFLMG_00103 2.9e-76 ctsR K Belongs to the CtsR family
HMGFFLMG_00104 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HMGFFLMG_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HMGFFLMG_00106 0.0 clpC O Belongs to the ClpA ClpB family
HMGFFLMG_00107 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMGFFLMG_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HMGFFLMG_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HMGFFLMG_00110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HMGFFLMG_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HMGFFLMG_00112 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMGFFLMG_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HMGFFLMG_00114 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMGFFLMG_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMGFFLMG_00116 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMGFFLMG_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HMGFFLMG_00118 1.5e-115 sigH K Belongs to the sigma-70 factor family
HMGFFLMG_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMGFFLMG_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HMGFFLMG_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMGFFLMG_00122 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMGFFLMG_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMGFFLMG_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMGFFLMG_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HMGFFLMG_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMGFFLMG_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMGFFLMG_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HMGFFLMG_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMGFFLMG_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMGFFLMG_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMGFFLMG_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMGFFLMG_00133 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HMGFFLMG_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HMGFFLMG_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMGFFLMG_00136 3e-105 rplD J Forms part of the polypeptide exit tunnel
HMGFFLMG_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMGFFLMG_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMGFFLMG_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMGFFLMG_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMGFFLMG_00141 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMGFFLMG_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMGFFLMG_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HMGFFLMG_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMGFFLMG_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMGFFLMG_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMGFFLMG_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMGFFLMG_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMGFFLMG_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMGFFLMG_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMGFFLMG_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMGFFLMG_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMGFFLMG_00153 1.9e-23 rpmD J Ribosomal protein L30
HMGFFLMG_00154 1.8e-72 rplO J binds to the 23S rRNA
HMGFFLMG_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMGFFLMG_00156 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMGFFLMG_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HMGFFLMG_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMGFFLMG_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMGFFLMG_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMGFFLMG_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMGFFLMG_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMGFFLMG_00163 3.6e-58 rplQ J Ribosomal protein L17
HMGFFLMG_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMGFFLMG_00165 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMGFFLMG_00166 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMGFFLMG_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMGFFLMG_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMGFFLMG_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HMGFFLMG_00170 8.2e-145 ybaJ Q Methyltransferase domain
HMGFFLMG_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
HMGFFLMG_00172 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMGFFLMG_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HMGFFLMG_00174 1.2e-84 gerD
HMGFFLMG_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HMGFFLMG_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HMGFFLMG_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
HMGFFLMG_00178 3.3e-39 S COG NOG15344 non supervised orthologous group
HMGFFLMG_00181 2e-08
HMGFFLMG_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
HMGFFLMG_00186 3.4e-39 S COG NOG14552 non supervised orthologous group
HMGFFLMG_00187 3.9e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HMGFFLMG_00189 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
HMGFFLMG_00190 2.2e-142 ybbA S Putative esterase
HMGFFLMG_00191 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_00192 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_00193 7.2e-167 feuA P Iron-uptake system-binding protein
HMGFFLMG_00194 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HMGFFLMG_00195 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
HMGFFLMG_00196 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HMGFFLMG_00197 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HMGFFLMG_00198 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMGFFLMG_00199 1.1e-150 ybbH K transcriptional
HMGFFLMG_00200 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMGFFLMG_00201 6.4e-87 ybbJ J acetyltransferase
HMGFFLMG_00202 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HMGFFLMG_00208 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_00209 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HMGFFLMG_00210 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMGFFLMG_00211 3e-225 ybbR S protein conserved in bacteria
HMGFFLMG_00212 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMGFFLMG_00213 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMGFFLMG_00214 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HMGFFLMG_00215 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
HMGFFLMG_00216 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMGFFLMG_00217 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HMGFFLMG_00218 0.0 ybcC S Belongs to the UPF0753 family
HMGFFLMG_00219 3.7e-96 can 4.2.1.1 P carbonic anhydrase
HMGFFLMG_00220 3.9e-47
HMGFFLMG_00221 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HMGFFLMG_00222 5.1e-50 ybzH K Helix-turn-helix domain
HMGFFLMG_00223 2e-203 ybcL EGP Major facilitator Superfamily
HMGFFLMG_00225 9.1e-239 J 4Fe-4S single cluster domain
HMGFFLMG_00226 1.6e-277 V CAAX protease self-immunity
HMGFFLMG_00227 1.9e-135 skfE V ABC transporter
HMGFFLMG_00228 4e-248 skfF S ABC transporter
HMGFFLMG_00229 7.8e-91 C HEAT repeats
HMGFFLMG_00230 9.6e-79 txn CO Thioredoxin-like
HMGFFLMG_00231 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMGFFLMG_00232 1.5e-123 T Transcriptional regulatory protein, C terminal
HMGFFLMG_00233 1.8e-173 T His Kinase A (phospho-acceptor) domain
HMGFFLMG_00235 1.6e-140 KLT Protein tyrosine kinase
HMGFFLMG_00236 4.8e-154 ybdN
HMGFFLMG_00237 1.5e-217 ybdO S Domain of unknown function (DUF4885)
HMGFFLMG_00238 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HMGFFLMG_00239 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HMGFFLMG_00240 4.9e-30 ybxH S Family of unknown function (DUF5370)
HMGFFLMG_00241 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
HMGFFLMG_00242 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HMGFFLMG_00243 4.9e-41 ybyB
HMGFFLMG_00244 2.3e-290 ybeC E amino acid
HMGFFLMG_00245 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMGFFLMG_00246 7.3e-258 glpT G -transporter
HMGFFLMG_00247 2.9e-35 S Protein of unknown function (DUF2651)
HMGFFLMG_00248 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
HMGFFLMG_00249 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
HMGFFLMG_00251 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HMGFFLMG_00252 8.8e-162 ybfH EG EamA-like transporter family
HMGFFLMG_00253 2.3e-145 msmR K AraC-like ligand binding domain
HMGFFLMG_00254 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMGFFLMG_00255 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HMGFFLMG_00257 2.5e-169 S Alpha/beta hydrolase family
HMGFFLMG_00258 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMGFFLMG_00259 2.7e-85 ybfM S SNARE associated Golgi protein
HMGFFLMG_00260 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HMGFFLMG_00261 3.2e-46 ybfN
HMGFFLMG_00262 4.3e-258 S Erythromycin esterase
HMGFFLMG_00263 6.7e-167 ybfP K Transcriptional regulator
HMGFFLMG_00264 3.9e-192 yceA S Belongs to the UPF0176 family
HMGFFLMG_00265 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMGFFLMG_00266 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMGFFLMG_00267 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMGFFLMG_00268 4.9e-128 K UTRA
HMGFFLMG_00270 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HMGFFLMG_00271 6.7e-262 mmuP E amino acid
HMGFFLMG_00272 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HMGFFLMG_00273 2.3e-257 agcS E Sodium alanine symporter
HMGFFLMG_00274 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
HMGFFLMG_00275 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
HMGFFLMG_00276 9e-170 glnL T Regulator
HMGFFLMG_00277 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HMGFFLMG_00278 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMGFFLMG_00279 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HMGFFLMG_00280 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HMGFFLMG_00281 1.5e-124 ycbG K FCD
HMGFFLMG_00282 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
HMGFFLMG_00283 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
HMGFFLMG_00284 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HMGFFLMG_00285 7.3e-172 eamA1 EG spore germination
HMGFFLMG_00286 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_00287 2.4e-170 T PhoQ Sensor
HMGFFLMG_00288 4.8e-168 ycbN V ABC transporter, ATP-binding protein
HMGFFLMG_00289 2.1e-115 S ABC-2 family transporter protein
HMGFFLMG_00290 8.2e-53 ycbP S Protein of unknown function (DUF2512)
HMGFFLMG_00291 1.3e-78 sleB 3.5.1.28 M Cell wall
HMGFFLMG_00292 6.6e-136 ycbR T vWA found in TerF C terminus
HMGFFLMG_00293 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HMGFFLMG_00294 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HMGFFLMG_00295 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMGFFLMG_00296 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMGFFLMG_00297 6.2e-210 ycbU E Selenocysteine lyase
HMGFFLMG_00298 5.8e-229 lmrB EGP the major facilitator superfamily
HMGFFLMG_00299 4.8e-102 yxaF K Transcriptional regulator
HMGFFLMG_00300 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HMGFFLMG_00301 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HMGFFLMG_00302 2e-59 S RDD family
HMGFFLMG_00303 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
HMGFFLMG_00304 2e-161 2.7.13.3 T GHKL domain
HMGFFLMG_00305 1.2e-126 lytR_2 T LytTr DNA-binding domain
HMGFFLMG_00306 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HMGFFLMG_00307 4.5e-203 natB CP ABC-2 family transporter protein
HMGFFLMG_00308 1.6e-174 yccK C Aldo keto reductase
HMGFFLMG_00309 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HMGFFLMG_00310 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_00311 7.4e-267 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_00312 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
HMGFFLMG_00313 5.5e-174 S response regulator aspartate phosphatase
HMGFFLMG_00314 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
HMGFFLMG_00315 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HMGFFLMG_00316 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
HMGFFLMG_00317 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HMGFFLMG_00318 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HMGFFLMG_00319 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMGFFLMG_00320 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HMGFFLMG_00321 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HMGFFLMG_00322 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HMGFFLMG_00323 6.3e-137 terC P Protein of unknown function (DUF475)
HMGFFLMG_00324 0.0 yceG S Putative component of 'biosynthetic module'
HMGFFLMG_00325 2e-192 yceH P Belongs to the TelA family
HMGFFLMG_00326 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
HMGFFLMG_00327 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
HMGFFLMG_00328 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HMGFFLMG_00329 5.1e-229 proV 3.6.3.32 E glycine betaine
HMGFFLMG_00330 1.3e-127 opuAB P glycine betaine
HMGFFLMG_00331 5.3e-164 opuAC E glycine betaine
HMGFFLMG_00332 1.2e-219 amhX S amidohydrolase
HMGFFLMG_00333 1e-257 ycgA S Membrane
HMGFFLMG_00334 1.1e-98 ycgB
HMGFFLMG_00335 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HMGFFLMG_00336 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMGFFLMG_00337 6.5e-293 lctP C L-lactate permease
HMGFFLMG_00338 6.2e-269 mdr EGP Major facilitator Superfamily
HMGFFLMG_00339 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HMGFFLMG_00340 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HMGFFLMG_00341 1.2e-151 yqcI S YqcI/YcgG family
HMGFFLMG_00342 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HMGFFLMG_00343 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HMGFFLMG_00344 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMGFFLMG_00345 2.5e-109 tmrB S AAA domain
HMGFFLMG_00346 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMGFFLMG_00347 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
HMGFFLMG_00348 2.2e-179 oxyR3 K LysR substrate binding domain
HMGFFLMG_00349 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HMGFFLMG_00350 2.9e-145 ycgL S Predicted nucleotidyltransferase
HMGFFLMG_00351 5.1e-170 ycgM E Proline dehydrogenase
HMGFFLMG_00352 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HMGFFLMG_00353 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMGFFLMG_00354 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HMGFFLMG_00355 2.6e-147 ycgQ S membrane
HMGFFLMG_00356 1.2e-139 ycgR S permeases
HMGFFLMG_00357 5.7e-163 I alpha/beta hydrolase fold
HMGFFLMG_00358 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HMGFFLMG_00359 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HMGFFLMG_00360 3.9e-56 nirD 1.7.1.15 P Nitrite reductase
HMGFFLMG_00361 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HMGFFLMG_00362 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMGFFLMG_00363 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HMGFFLMG_00364 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
HMGFFLMG_00365 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HMGFFLMG_00366 5.5e-109 yciB M ErfK YbiS YcfS YnhG
HMGFFLMG_00367 1.4e-228 yciC S GTPases (G3E family)
HMGFFLMG_00368 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
HMGFFLMG_00369 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HMGFFLMG_00372 3.3e-77 yckC S membrane
HMGFFLMG_00373 3.5e-52 yckD S Protein of unknown function (DUF2680)
HMGFFLMG_00374 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMGFFLMG_00375 3.4e-70 nin S Competence protein J (ComJ)
HMGFFLMG_00376 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
HMGFFLMG_00377 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
HMGFFLMG_00378 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HMGFFLMG_00379 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HMGFFLMG_00380 1.3e-63 hxlR K transcriptional
HMGFFLMG_00381 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMGFFLMG_00382 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMGFFLMG_00383 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HMGFFLMG_00384 5.7e-140 srfAD Q thioesterase
HMGFFLMG_00385 4.2e-228 EGP Major Facilitator Superfamily
HMGFFLMG_00386 4.9e-91 S YcxB-like protein
HMGFFLMG_00387 7.4e-164 ycxC EG EamA-like transporter family
HMGFFLMG_00388 4.4e-255 ycxD K GntR family transcriptional regulator
HMGFFLMG_00389 4.4e-75 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HMGFFLMG_00390 4.4e-115 yczE S membrane
HMGFFLMG_00391 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HMGFFLMG_00392 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HMGFFLMG_00393 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HMGFFLMG_00394 4.9e-162 bsdA K LysR substrate binding domain
HMGFFLMG_00395 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HMGFFLMG_00396 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HMGFFLMG_00397 4e-39 bsdD 4.1.1.61 S response to toxic substance
HMGFFLMG_00398 1.1e-83 yclD
HMGFFLMG_00399 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
HMGFFLMG_00400 1.5e-267 dtpT E amino acid peptide transporter
HMGFFLMG_00401 2.9e-310 yclG M Pectate lyase superfamily protein
HMGFFLMG_00403 6.8e-282 gerKA EG Spore germination protein
HMGFFLMG_00404 1.3e-232 gerKC S spore germination
HMGFFLMG_00405 9.9e-200 gerKB F Spore germination protein
HMGFFLMG_00406 3.9e-122 yclH P ABC transporter
HMGFFLMG_00407 1.7e-204 yclI V ABC transporter (permease) YclI
HMGFFLMG_00408 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_00409 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HMGFFLMG_00410 5.2e-71 S aspartate phosphatase
HMGFFLMG_00414 1.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMGFFLMG_00415 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_00416 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_00417 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HMGFFLMG_00418 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HMGFFLMG_00419 1.4e-251 ycnB EGP Major facilitator Superfamily
HMGFFLMG_00420 6.5e-154 ycnC K Transcriptional regulator
HMGFFLMG_00421 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HMGFFLMG_00422 1.6e-45 ycnE S Monooxygenase
HMGFFLMG_00423 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HMGFFLMG_00424 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMGFFLMG_00425 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMGFFLMG_00426 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMGFFLMG_00427 6.1e-149 glcU U Glucose uptake
HMGFFLMG_00428 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMGFFLMG_00429 1.3e-100 ycnI S protein conserved in bacteria
HMGFFLMG_00430 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
HMGFFLMG_00431 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HMGFFLMG_00432 7.3e-56
HMGFFLMG_00433 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HMGFFLMG_00434 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HMGFFLMG_00435 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HMGFFLMG_00436 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HMGFFLMG_00437 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HMGFFLMG_00438 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HMGFFLMG_00439 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HMGFFLMG_00440 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HMGFFLMG_00442 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HMGFFLMG_00443 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
HMGFFLMG_00444 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HMGFFLMG_00445 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
HMGFFLMG_00446 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HMGFFLMG_00447 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HMGFFLMG_00448 1.2e-132 kipR K Transcriptional regulator
HMGFFLMG_00449 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
HMGFFLMG_00451 1.4e-49 yczJ S biosynthesis
HMGFFLMG_00452 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HMGFFLMG_00453 2.8e-176 ydhF S Oxidoreductase
HMGFFLMG_00454 0.0 mtlR K transcriptional regulator, MtlR
HMGFFLMG_00455 1.4e-294 ydaB IQ acyl-CoA ligase
HMGFFLMG_00456 1.1e-99 ydaC Q Methyltransferase domain
HMGFFLMG_00457 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMGFFLMG_00458 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HMGFFLMG_00459 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMGFFLMG_00460 6.8e-77 ydaG 1.4.3.5 S general stress protein
HMGFFLMG_00461 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HMGFFLMG_00462 5.1e-47 ydzA EGP Major facilitator Superfamily
HMGFFLMG_00463 2.5e-74 lrpC K Transcriptional regulator
HMGFFLMG_00464 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMGFFLMG_00465 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HMGFFLMG_00466 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
HMGFFLMG_00467 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HMGFFLMG_00468 4.5e-233 ydaM M Glycosyl transferase family group 2
HMGFFLMG_00469 0.0 ydaN S Bacterial cellulose synthase subunit
HMGFFLMG_00470 0.0 ydaO E amino acid
HMGFFLMG_00471 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HMGFFLMG_00472 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HMGFFLMG_00473 9.4e-40
HMGFFLMG_00474 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HMGFFLMG_00476 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HMGFFLMG_00477 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HMGFFLMG_00479 8.9e-59 ydbB G Cupin domain
HMGFFLMG_00480 2.8e-63 ydbC S Domain of unknown function (DUF4937
HMGFFLMG_00481 3.2e-155 ydbD P Catalase
HMGFFLMG_00482 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HMGFFLMG_00483 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HMGFFLMG_00484 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
HMGFFLMG_00485 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMGFFLMG_00486 4.4e-181 ydbI S AI-2E family transporter
HMGFFLMG_00487 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
HMGFFLMG_00488 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMGFFLMG_00489 2.7e-52 ydbL
HMGFFLMG_00490 1.6e-213 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HMGFFLMG_00491 2.5e-18 S Fur-regulated basic protein B
HMGFFLMG_00492 2.2e-07 S Fur-regulated basic protein A
HMGFFLMG_00493 6.4e-146 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMGFFLMG_00494 8.6e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMGFFLMG_00495 1.8e-198 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMGFFLMG_00496 6e-247 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMGFFLMG_00497 1e-244 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMGFFLMG_00498 3e-81 ydbS S Bacterial PH domain
HMGFFLMG_00499 3.3e-243 ydbT S Membrane
HMGFFLMG_00500 4.9e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HMGFFLMG_00501 1.1e-54 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMGFFLMG_00502 7.7e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HMGFFLMG_00503 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMGFFLMG_00504 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HMGFFLMG_00505 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HMGFFLMG_00506 1.3e-143 rsbR T Positive regulator of sigma-B
HMGFFLMG_00507 5.2e-57 rsbS T antagonist
HMGFFLMG_00508 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HMGFFLMG_00509 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HMGFFLMG_00510 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HMGFFLMG_00511 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HMGFFLMG_00512 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMGFFLMG_00513 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HMGFFLMG_00517 1.5e-82 ydcG S EVE domain
HMGFFLMG_00518 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
HMGFFLMG_00519 0.0 yhgF K COG2183 Transcriptional accessory protein
HMGFFLMG_00520 1.6e-84 ydcK S Belongs to the SprT family
HMGFFLMG_00528 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMGFFLMG_00529 2.4e-71 lrpA K transcriptional
HMGFFLMG_00530 3.9e-78 lrpB K transcriptional
HMGFFLMG_00531 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
HMGFFLMG_00532 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HMGFFLMG_00533 5e-227 ydeG EGP Major facilitator Superfamily
HMGFFLMG_00538 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HMGFFLMG_00539 8.7e-30 cspL K Cold shock
HMGFFLMG_00540 6.1e-79 carD K Transcription factor
HMGFFLMG_00541 4.6e-35 ydzE EG spore germination
HMGFFLMG_00542 1.1e-166 rhaS5 K AraC-like ligand binding domain
HMGFFLMG_00543 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HMGFFLMG_00544 2.5e-166 ydeE K AraC family transcriptional regulator
HMGFFLMG_00545 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMGFFLMG_00546 3.4e-220 ydeG EGP Major facilitator superfamily
HMGFFLMG_00547 2.9e-47 ydeH
HMGFFLMG_00548 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HMGFFLMG_00549 4e-116
HMGFFLMG_00550 1.8e-153 ydeK EG -transporter
HMGFFLMG_00551 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMGFFLMG_00552 4.2e-74 maoC I N-terminal half of MaoC dehydratase
HMGFFLMG_00553 8.6e-107 ydeN S Serine hydrolase
HMGFFLMG_00554 1.1e-58 K HxlR-like helix-turn-helix
HMGFFLMG_00555 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HMGFFLMG_00556 4.8e-69 ydeP K Transcriptional regulator
HMGFFLMG_00557 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HMGFFLMG_00558 1.2e-195 ydeR EGP Major facilitator Superfamily
HMGFFLMG_00559 8.4e-105 ydeS K Transcriptional regulator
HMGFFLMG_00560 1.3e-57 arsR K transcriptional
HMGFFLMG_00561 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HMGFFLMG_00562 7.2e-149 ydfB J GNAT acetyltransferase
HMGFFLMG_00563 1e-162 ydfC EG EamA-like transporter family
HMGFFLMG_00564 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMGFFLMG_00565 5.9e-117 ydfE S Flavin reductase like domain
HMGFFLMG_00566 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HMGFFLMG_00567 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HMGFFLMG_00569 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
HMGFFLMG_00570 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMGFFLMG_00571 0.0 ydfJ S drug exporters of the RND superfamily
HMGFFLMG_00572 1.9e-177 S Alpha/beta hydrolase family
HMGFFLMG_00573 5.9e-118 S Protein of unknown function (DUF554)
HMGFFLMG_00574 3.2e-147 K Bacterial transcription activator, effector binding domain
HMGFFLMG_00575 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMGFFLMG_00576 9.6e-112 ydfN C nitroreductase
HMGFFLMG_00577 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HMGFFLMG_00578 8.8e-63 mhqP S DoxX
HMGFFLMG_00579 1.3e-57 traF CO Thioredoxin
HMGFFLMG_00580 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HMGFFLMG_00581 6.3e-29
HMGFFLMG_00583 4.4e-118 ydfR S Protein of unknown function (DUF421)
HMGFFLMG_00584 5.2e-122 ydfS S Protein of unknown function (DUF421)
HMGFFLMG_00585 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
HMGFFLMG_00586 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HMGFFLMG_00587 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HMGFFLMG_00588 1.5e-101 K Bacterial regulatory proteins, tetR family
HMGFFLMG_00589 1.9e-53 S DoxX-like family
HMGFFLMG_00590 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
HMGFFLMG_00591 4.2e-308 expZ S ABC transporter
HMGFFLMG_00592 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HMGFFLMG_00593 4.6e-91 dinB S DinB family
HMGFFLMG_00594 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
HMGFFLMG_00595 0.0 ydgH S drug exporters of the RND superfamily
HMGFFLMG_00596 1e-113 drgA C nitroreductase
HMGFFLMG_00597 1.1e-69 ydgJ K Winged helix DNA-binding domain
HMGFFLMG_00598 2.5e-209 tcaB EGP Major facilitator Superfamily
HMGFFLMG_00599 1.2e-121 ydhB S membrane transporter protein
HMGFFLMG_00600 6.5e-122 ydhC K FCD
HMGFFLMG_00601 3.3e-244 ydhD M Glycosyl hydrolase
HMGFFLMG_00602 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HMGFFLMG_00603 1.9e-127
HMGFFLMG_00604 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HMGFFLMG_00605 4.6e-69 frataxin S Domain of unknown function (DU1801)
HMGFFLMG_00607 4.1e-86 K Acetyltransferase (GNAT) domain
HMGFFLMG_00608 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMGFFLMG_00609 1.7e-99 ydhK M Protein of unknown function (DUF1541)
HMGFFLMG_00610 4.6e-200 pbuE EGP Major facilitator Superfamily
HMGFFLMG_00611 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HMGFFLMG_00612 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HMGFFLMG_00613 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMGFFLMG_00614 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMGFFLMG_00615 3.9e-133 ydhQ K UTRA
HMGFFLMG_00616 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HMGFFLMG_00617 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMGFFLMG_00618 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HMGFFLMG_00619 8.7e-78 ydhU P Catalase
HMGFFLMG_00620 1.1e-16 ydhU P Manganese containing catalase
HMGFFLMG_00623 3.4e-39 S COG NOG14552 non supervised orthologous group
HMGFFLMG_00624 7.8e-08
HMGFFLMG_00626 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HMGFFLMG_00627 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HMGFFLMG_00628 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HMGFFLMG_00629 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HMGFFLMG_00630 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMGFFLMG_00631 0.0 ydiF S ABC transporter
HMGFFLMG_00632 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HMGFFLMG_00633 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMGFFLMG_00634 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HMGFFLMG_00635 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMGFFLMG_00636 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HMGFFLMG_00637 7.9e-129 ydiL S CAAX protease self-immunity
HMGFFLMG_00638 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMGFFLMG_00639 1.2e-278 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMGFFLMG_00640 1.5e-24 S Protein of unknown function (DUF4064)
HMGFFLMG_00642 0.0 K NB-ARC domain
HMGFFLMG_00643 3.2e-200 gutB 1.1.1.14 E Dehydrogenase
HMGFFLMG_00644 5.8e-250 gutA G MFS/sugar transport protein
HMGFFLMG_00645 4.4e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HMGFFLMG_00646 4.3e-31 yjdJ S Domain of unknown function (DUF4306)
HMGFFLMG_00647 3.3e-113 pspA KT Phage shock protein A
HMGFFLMG_00648 2.6e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMGFFLMG_00649 3.1e-120 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HMGFFLMG_00650 1.1e-149 ydjI S virion core protein (lumpy skin disease virus)
HMGFFLMG_00651 0.0 yrhL I Acyltransferase family
HMGFFLMG_00652 1.4e-145 rsiV S Protein of unknown function (DUF3298)
HMGFFLMG_00653 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_00654 4.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HMGFFLMG_00655 7.1e-62 ydjM M Lytic transglycolase
HMGFFLMG_00656 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
HMGFFLMG_00658 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HMGFFLMG_00659 7.3e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HMGFFLMG_00660 2.2e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMGFFLMG_00661 1.7e-176 yeaC S COG0714 MoxR-like ATPases
HMGFFLMG_00662 5.4e-212 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HMGFFLMG_00663 0.0 yebA E COG1305 Transglutaminase-like enzymes
HMGFFLMG_00664 1.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMGFFLMG_00665 7.6e-140 6.3.4.18, 6.3.5.5 F 5-(carboxyamino)imidazole ribonucleotide synthase activity
HMGFFLMG_00666 5.1e-117 F ATP-grasp domain
HMGFFLMG_00667 3.9e-106 pphA 5.4.2.9 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HMGFFLMG_00668 4.1e-135 aspC 2.6.1.1 E DegT/DnrJ/EryC1/StrS aminotransferase family
HMGFFLMG_00669 5.1e-149 yqjV G Major Facilitator Superfamily
HMGFFLMG_00670 8.6e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_00671 2.4e-246 S Domain of unknown function (DUF4179)
HMGFFLMG_00672 6.2e-209 pbuG S permease
HMGFFLMG_00673 5.6e-133 yebC M Membrane
HMGFFLMG_00675 2e-92 yebE S UPF0316 protein
HMGFFLMG_00676 6.1e-28 yebG S NETI protein
HMGFFLMG_00677 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMGFFLMG_00678 2.6e-222 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMGFFLMG_00679 3.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMGFFLMG_00680 1.2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HMGFFLMG_00681 8.4e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMGFFLMG_00682 7.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMGFFLMG_00683 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMGFFLMG_00684 3.6e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMGFFLMG_00685 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HMGFFLMG_00686 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMGFFLMG_00687 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HMGFFLMG_00688 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
HMGFFLMG_00689 3.5e-73 K helix_turn_helix ASNC type
HMGFFLMG_00690 2.3e-232 yjeH E Amino acid permease
HMGFFLMG_00691 2.7e-27 S Protein of unknown function (DUF2892)
HMGFFLMG_00692 0.0 yerA 3.5.4.2 F adenine deaminase
HMGFFLMG_00693 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
HMGFFLMG_00694 4.8e-51 yerC S protein conserved in bacteria
HMGFFLMG_00695 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HMGFFLMG_00697 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HMGFFLMG_00698 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMGFFLMG_00699 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMGFFLMG_00700 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HMGFFLMG_00701 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
HMGFFLMG_00702 1.6e-123 sapB S MgtC SapB transporter
HMGFFLMG_00703 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMGFFLMG_00704 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMGFFLMG_00705 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMGFFLMG_00706 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMGFFLMG_00707 4e-156 yerO K Transcriptional regulator
HMGFFLMG_00708 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HMGFFLMG_00709 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HMGFFLMG_00710 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMGFFLMG_00711 3.2e-98 L Recombinase
HMGFFLMG_00712 3.2e-53 L Resolvase, N terminal domain
HMGFFLMG_00713 0.0 yeeA V Type II restriction enzyme, methylase subunits
HMGFFLMG_00714 0.0 yeeB L DEAD-like helicases superfamily
HMGFFLMG_00715 1.8e-212 pstS P T5orf172
HMGFFLMG_00717 6.2e-31 S Colicin immunity protein / pyocin immunity protein
HMGFFLMG_00718 5.5e-83 S Protein of unknown function, DUF600
HMGFFLMG_00719 0.0 L nucleic acid phosphodiester bond hydrolysis
HMGFFLMG_00720 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
HMGFFLMG_00721 5.5e-214 S Tetratricopeptide repeat
HMGFFLMG_00723 9.4e-127 yeeN K transcriptional regulatory protein
HMGFFLMG_00725 1.2e-103 dhaR3 K Transcriptional regulator
HMGFFLMG_00726 9.7e-82 yesE S SnoaL-like domain
HMGFFLMG_00727 2.2e-159 yesF GM NAD(P)H-binding
HMGFFLMG_00728 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HMGFFLMG_00729 1.5e-45 cotJB S CotJB protein
HMGFFLMG_00730 5.2e-104 cotJC P Spore Coat
HMGFFLMG_00731 4.2e-103 yesJ K Acetyltransferase (GNAT) family
HMGFFLMG_00733 4.4e-104 yesL S Protein of unknown function, DUF624
HMGFFLMG_00734 0.0 yesM 2.7.13.3 T Histidine kinase
HMGFFLMG_00735 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
HMGFFLMG_00736 5e-248 yesO G Bacterial extracellular solute-binding protein
HMGFFLMG_00737 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HMGFFLMG_00738 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
HMGFFLMG_00739 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HMGFFLMG_00740 0.0 yesS K Transcriptional regulator
HMGFFLMG_00741 3.8e-133 E GDSL-like Lipase/Acylhydrolase
HMGFFLMG_00742 8.9e-132 yesU S Domain of unknown function (DUF1961)
HMGFFLMG_00743 1e-113 yesV S Protein of unknown function, DUF624
HMGFFLMG_00744 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HMGFFLMG_00745 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HMGFFLMG_00746 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
HMGFFLMG_00747 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HMGFFLMG_00748 0.0 yetA
HMGFFLMG_00749 9.6e-291 lplA G Bacterial extracellular solute-binding protein
HMGFFLMG_00750 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HMGFFLMG_00751 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HMGFFLMG_00752 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HMGFFLMG_00753 6.1e-123 yetF S membrane
HMGFFLMG_00754 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HMGFFLMG_00755 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMGFFLMG_00756 2.2e-34
HMGFFLMG_00757 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMGFFLMG_00758 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMGFFLMG_00759 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HMGFFLMG_00760 5.3e-105 yetJ S Belongs to the BI1 family
HMGFFLMG_00761 5.4e-159 yetK EG EamA-like transporter family
HMGFFLMG_00762 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HMGFFLMG_00763 7.8e-213 yetM CH FAD binding domain
HMGFFLMG_00764 3.6e-199 yetN S Protein of unknown function (DUF3900)
HMGFFLMG_00765 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HMGFFLMG_00766 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMGFFLMG_00767 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
HMGFFLMG_00768 1.9e-172 yfnG 4.2.1.45 M dehydratase
HMGFFLMG_00769 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
HMGFFLMG_00770 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HMGFFLMG_00771 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
HMGFFLMG_00772 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
HMGFFLMG_00773 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMGFFLMG_00774 1.3e-241 yfnA E amino acid
HMGFFLMG_00775 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMGFFLMG_00776 1.1e-113 yfmS NT chemotaxis protein
HMGFFLMG_00777 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HMGFFLMG_00778 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
HMGFFLMG_00779 2.8e-70 yfmP K transcriptional
HMGFFLMG_00780 1.5e-209 yfmO EGP Major facilitator Superfamily
HMGFFLMG_00781 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HMGFFLMG_00782 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HMGFFLMG_00783 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
HMGFFLMG_00784 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
HMGFFLMG_00785 7.7e-214 G Major Facilitator Superfamily
HMGFFLMG_00786 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
HMGFFLMG_00787 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HMGFFLMG_00788 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_00789 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_00790 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HMGFFLMG_00791 2.9e-24 S Protein of unknown function (DUF3212)
HMGFFLMG_00792 7.6e-58 yflT S Heat induced stress protein YflT
HMGFFLMG_00793 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HMGFFLMG_00794 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
HMGFFLMG_00795 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HMGFFLMG_00796 8.9e-119 citT T response regulator
HMGFFLMG_00797 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
HMGFFLMG_00799 8.5e-227 citM C Citrate transporter
HMGFFLMG_00800 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HMGFFLMG_00801 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HMGFFLMG_00802 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMGFFLMG_00803 9e-124 yflK S protein conserved in bacteria
HMGFFLMG_00804 4e-18 yflJ S Protein of unknown function (DUF2639)
HMGFFLMG_00805 4.1e-19 yflI
HMGFFLMG_00806 2.4e-50 yflH S Protein of unknown function (DUF3243)
HMGFFLMG_00807 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HMGFFLMG_00808 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HMGFFLMG_00809 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMGFFLMG_00810 6e-67 yhdN S Domain of unknown function (DUF1992)
HMGFFLMG_00811 3.2e-256 agcS_1 E Sodium alanine symporter
HMGFFLMG_00812 1.6e-194 E Spore germination protein
HMGFFLMG_00814 5.1e-207 yfkR S spore germination
HMGFFLMG_00815 1.5e-283 yfkQ EG Spore germination protein
HMGFFLMG_00816 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMGFFLMG_00817 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HMGFFLMG_00818 1.8e-133 treR K transcriptional
HMGFFLMG_00819 1.6e-125 yfkO C nitroreductase
HMGFFLMG_00820 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMGFFLMG_00821 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HMGFFLMG_00822 6.8e-207 ydiM EGP Major facilitator Superfamily
HMGFFLMG_00823 2.1e-29 yfkK S Belongs to the UPF0435 family
HMGFFLMG_00824 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMGFFLMG_00825 8.4e-51 yfkI S gas vesicle protein
HMGFFLMG_00826 9.7e-144 yihY S Belongs to the UPF0761 family
HMGFFLMG_00827 5e-08
HMGFFLMG_00828 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HMGFFLMG_00829 6.1e-183 cax P COG0387 Ca2 H antiporter
HMGFFLMG_00830 1.2e-146 yfkD S YfkD-like protein
HMGFFLMG_00831 6e-149 yfkC M Mechanosensitive ion channel
HMGFFLMG_00832 5.4e-222 yfkA S YfkB-like domain
HMGFFLMG_00833 1.1e-26 yfjT
HMGFFLMG_00834 2.6e-154 pdaA G deacetylase
HMGFFLMG_00835 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HMGFFLMG_00836 3.8e-184 corA P Mediates influx of magnesium ions
HMGFFLMG_00837 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HMGFFLMG_00838 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMGFFLMG_00839 1.6e-39 S YfzA-like protein
HMGFFLMG_00840 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMGFFLMG_00841 3.9e-86 yfjM S Psort location Cytoplasmic, score
HMGFFLMG_00842 3e-29 yfjL
HMGFFLMG_00843 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HMGFFLMG_00844 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMGFFLMG_00845 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMGFFLMG_00846 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HMGFFLMG_00847 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HMGFFLMG_00848 1.2e-25 sspH S Belongs to the SspH family
HMGFFLMG_00849 4e-56 yfjF S UPF0060 membrane protein
HMGFFLMG_00850 1.3e-80 S Family of unknown function (DUF5381)
HMGFFLMG_00851 1.8e-101 yfjD S Family of unknown function (DUF5381)
HMGFFLMG_00852 4.1e-144 yfjC
HMGFFLMG_00853 9.2e-191 yfjB
HMGFFLMG_00854 1.1e-44 yfjA S Belongs to the WXG100 family
HMGFFLMG_00855 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HMGFFLMG_00856 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
HMGFFLMG_00857 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMGFFLMG_00858 2.1e-310 yfiB3 V ABC transporter
HMGFFLMG_00859 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HMGFFLMG_00860 9.8e-65 mhqP S DoxX
HMGFFLMG_00861 5.7e-163 yfiE 1.13.11.2 S glyoxalase
HMGFFLMG_00862 1.5e-177 K AraC-like ligand binding domain
HMGFFLMG_00863 1.8e-262 iolT EGP Major facilitator Superfamily
HMGFFLMG_00864 8.4e-184 G Xylose isomerase
HMGFFLMG_00865 1.1e-233 S Oxidoreductase
HMGFFLMG_00867 1.1e-214 yxjM T Histidine kinase
HMGFFLMG_00868 3.2e-113 KT LuxR family transcriptional regulator
HMGFFLMG_00869 6.2e-171 V ABC transporter, ATP-binding protein
HMGFFLMG_00870 9.8e-214 V ABC-2 family transporter protein
HMGFFLMG_00871 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
HMGFFLMG_00872 8.3e-99 padR K transcriptional
HMGFFLMG_00873 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HMGFFLMG_00874 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HMGFFLMG_00875 2e-109 yfiR K Transcriptional regulator
HMGFFLMG_00876 5.1e-221 yfiS EGP Major facilitator Superfamily
HMGFFLMG_00877 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
HMGFFLMG_00878 8.7e-287 yfiU EGP Major facilitator Superfamily
HMGFFLMG_00879 3.1e-81 yfiV K transcriptional
HMGFFLMG_00880 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMGFFLMG_00881 6.2e-182 yfiY P ABC transporter substrate-binding protein
HMGFFLMG_00882 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_00883 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_00884 1.8e-167 yfhB 5.3.3.17 S PhzF family
HMGFFLMG_00885 3.9e-107 yfhC C nitroreductase
HMGFFLMG_00886 2.1e-25 yfhD S YfhD-like protein
HMGFFLMG_00888 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
HMGFFLMG_00889 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HMGFFLMG_00890 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HMGFFLMG_00892 1.1e-209 yfhI EGP Major facilitator Superfamily
HMGFFLMG_00893 6.2e-20 sspK S reproduction
HMGFFLMG_00894 1.3e-44 yfhJ S WVELL protein
HMGFFLMG_00895 9.2e-92 batE T Bacterial SH3 domain homologues
HMGFFLMG_00896 3.5e-51 yfhL S SdpI/YhfL protein family
HMGFFLMG_00897 6.7e-172 yfhM S Alpha beta hydrolase
HMGFFLMG_00898 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HMGFFLMG_00899 0.0 yfhO S Bacterial membrane protein YfhO
HMGFFLMG_00900 5.5e-186 yfhP S membrane-bound metal-dependent
HMGFFLMG_00901 7.8e-212 mutY L A G-specific
HMGFFLMG_00902 6.9e-36 yfhS
HMGFFLMG_00903 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMGFFLMG_00904 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HMGFFLMG_00905 1.5e-37 ygaB S YgaB-like protein
HMGFFLMG_00906 1.3e-104 ygaC J Belongs to the UPF0374 family
HMGFFLMG_00907 1.8e-301 ygaD V ABC transporter
HMGFFLMG_00908 8.7e-180 ygaE S Membrane
HMGFFLMG_00909 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HMGFFLMG_00910 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
HMGFFLMG_00911 4e-80 perR P Belongs to the Fur family
HMGFFLMG_00912 1.5e-56 ygzB S UPF0295 protein
HMGFFLMG_00913 6.7e-167 ygxA S Nucleotidyltransferase-like
HMGFFLMG_00914 3.4e-39 S COG NOG14552 non supervised orthologous group
HMGFFLMG_00919 7.8e-08
HMGFFLMG_00927 2e-08
HMGFFLMG_00931 2.7e-143 spo0M S COG4326 Sporulation control protein
HMGFFLMG_00932 3e-27
HMGFFLMG_00933 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HMGFFLMG_00934 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HMGFFLMG_00935 1.9e-266 ygaK C Berberine and berberine like
HMGFFLMG_00937 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HMGFFLMG_00938 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HMGFFLMG_00939 1.7e-171 ssuA M Sulfonate ABC transporter
HMGFFLMG_00940 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HMGFFLMG_00941 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HMGFFLMG_00943 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMGFFLMG_00944 4.1e-78 ygaO
HMGFFLMG_00945 4.4e-29 K Transcriptional regulator
HMGFFLMG_00947 7.9e-114 yhzB S B3/4 domain
HMGFFLMG_00948 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HMGFFLMG_00949 4.4e-177 yhbB S Putative amidase domain
HMGFFLMG_00950 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMGFFLMG_00951 1.2e-109 yhbD K Protein of unknown function (DUF4004)
HMGFFLMG_00952 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HMGFFLMG_00953 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HMGFFLMG_00954 0.0 prkA T Ser protein kinase
HMGFFLMG_00955 2.5e-225 yhbH S Belongs to the UPF0229 family
HMGFFLMG_00956 2.2e-76 yhbI K DNA-binding transcription factor activity
HMGFFLMG_00957 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HMGFFLMG_00958 3.1e-271 yhcA EGP Major facilitator Superfamily
HMGFFLMG_00959 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HMGFFLMG_00960 2.8e-37 yhcC
HMGFFLMG_00961 7.8e-55
HMGFFLMG_00962 6.6e-60 yhcF K Transcriptional regulator
HMGFFLMG_00963 1.6e-123 yhcG V ABC transporter, ATP-binding protein
HMGFFLMG_00964 2.6e-166 yhcH V ABC transporter, ATP-binding protein
HMGFFLMG_00965 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMGFFLMG_00966 1e-30 cspB K Cold-shock protein
HMGFFLMG_00967 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
HMGFFLMG_00968 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HMGFFLMG_00969 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMGFFLMG_00970 3.7e-44 yhcM
HMGFFLMG_00971 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMGFFLMG_00972 2.5e-167 yhcP
HMGFFLMG_00973 5.2e-100 yhcQ M Spore coat protein
HMGFFLMG_00974 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HMGFFLMG_00975 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HMGFFLMG_00976 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMGFFLMG_00977 9.3e-68 yhcU S Family of unknown function (DUF5365)
HMGFFLMG_00978 9.9e-68 yhcV S COG0517 FOG CBS domain
HMGFFLMG_00979 4.6e-120 yhcW 5.4.2.6 S hydrolase
HMGFFLMG_00980 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HMGFFLMG_00981 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMGFFLMG_00982 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HMGFFLMG_00983 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HMGFFLMG_00984 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMGFFLMG_00985 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HMGFFLMG_00986 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HMGFFLMG_00987 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
HMGFFLMG_00988 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMGFFLMG_00989 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HMGFFLMG_00990 1.2e-38 yhdB S YhdB-like protein
HMGFFLMG_00991 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HMGFFLMG_00992 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HMGFFLMG_00993 3.5e-76 nsrR K Transcriptional regulator
HMGFFLMG_00994 8.7e-239 ygxB M Conserved TM helix
HMGFFLMG_00995 2.1e-276 ycgB S Stage V sporulation protein R
HMGFFLMG_00996 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HMGFFLMG_00997 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HMGFFLMG_00998 3.8e-162 citR K Transcriptional regulator
HMGFFLMG_00999 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
HMGFFLMG_01000 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMGFFLMG_01001 3.4e-250 yhdG E amino acid
HMGFFLMG_01002 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HMGFFLMG_01003 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMGFFLMG_01004 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMGFFLMG_01005 8.1e-45 yhdK S Sigma-M inhibitor protein
HMGFFLMG_01006 6.6e-201 yhdL S Sigma factor regulator N-terminal
HMGFFLMG_01007 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_01008 1.5e-191 yhdN C Aldo keto reductase
HMGFFLMG_01009 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HMGFFLMG_01010 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HMGFFLMG_01011 4.1e-74 cueR K transcriptional
HMGFFLMG_01012 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
HMGFFLMG_01013 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HMGFFLMG_01014 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMGFFLMG_01015 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMGFFLMG_01016 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMGFFLMG_01018 6.6e-204 yhdY M Mechanosensitive ion channel
HMGFFLMG_01019 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HMGFFLMG_01020 1.7e-151 yheN G deacetylase
HMGFFLMG_01021 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HMGFFLMG_01022 2.2e-233 nhaC C Na H antiporter
HMGFFLMG_01023 3.1e-84 nhaX T Belongs to the universal stress protein A family
HMGFFLMG_01024 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HMGFFLMG_01025 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HMGFFLMG_01026 3.7e-111 yheG GM NAD(P)H-binding
HMGFFLMG_01027 6.3e-28 sspB S spore protein
HMGFFLMG_01028 1.3e-36 yheE S Family of unknown function (DUF5342)
HMGFFLMG_01029 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HMGFFLMG_01030 4.3e-216 yheC HJ YheC/D like ATP-grasp
HMGFFLMG_01031 6.7e-204 yheB S Belongs to the UPF0754 family
HMGFFLMG_01032 9.5e-48 yheA S Belongs to the UPF0342 family
HMGFFLMG_01033 3.1e-206 yhaZ L DNA alkylation repair enzyme
HMGFFLMG_01034 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HMGFFLMG_01035 7.1e-294 hemZ H coproporphyrinogen III oxidase
HMGFFLMG_01036 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HMGFFLMG_01037 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HMGFFLMG_01039 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HMGFFLMG_01040 1.1e-26 S YhzD-like protein
HMGFFLMG_01041 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HMGFFLMG_01042 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HMGFFLMG_01043 3.6e-227 yhaO L DNA repair exonuclease
HMGFFLMG_01044 0.0 yhaN L AAA domain
HMGFFLMG_01045 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HMGFFLMG_01046 1.6e-21 yhaL S Sporulation protein YhaL
HMGFFLMG_01047 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMGFFLMG_01048 8.7e-90 yhaK S Putative zincin peptidase
HMGFFLMG_01049 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HMGFFLMG_01050 1e-113 hpr K Negative regulator of protease production and sporulation
HMGFFLMG_01051 7e-39 yhaH S YtxH-like protein
HMGFFLMG_01052 3.6e-80 trpP S Tryptophan transporter TrpP
HMGFFLMG_01053 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMGFFLMG_01054 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HMGFFLMG_01055 4.6e-137 ecsA V transporter (ATP-binding protein)
HMGFFLMG_01056 1.8e-215 ecsB U ABC transporter
HMGFFLMG_01057 4.8e-115 ecsC S EcsC protein family
HMGFFLMG_01058 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HMGFFLMG_01059 4.2e-248 yhfA C membrane
HMGFFLMG_01060 5.4e-10 1.15.1.2 C Rubrerythrin
HMGFFLMG_01061 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HMGFFLMG_01062 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMGFFLMG_01063 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HMGFFLMG_01064 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HMGFFLMG_01065 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HMGFFLMG_01066 1.4e-101 yhgD K Transcriptional regulator
HMGFFLMG_01067 1e-238 yhgE S YhgE Pip N-terminal domain protein
HMGFFLMG_01068 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMGFFLMG_01069 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
HMGFFLMG_01070 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HMGFFLMG_01071 1.7e-72 3.4.13.21 S ASCH
HMGFFLMG_01072 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMGFFLMG_01073 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HMGFFLMG_01074 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
HMGFFLMG_01075 2.6e-112 yhfK GM NmrA-like family
HMGFFLMG_01076 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HMGFFLMG_01077 1.9e-65 yhfM
HMGFFLMG_01078 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
HMGFFLMG_01079 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HMGFFLMG_01080 9.2e-80 VY92_01935 K acetyltransferase
HMGFFLMG_01081 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HMGFFLMG_01082 4.3e-159 yfmC M Periplasmic binding protein
HMGFFLMG_01083 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HMGFFLMG_01084 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
HMGFFLMG_01085 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HMGFFLMG_01086 5e-91 bioY S BioY family
HMGFFLMG_01087 1.7e-182 hemAT NT chemotaxis protein
HMGFFLMG_01088 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HMGFFLMG_01089 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMGFFLMG_01090 1.3e-32 yhzC S IDEAL
HMGFFLMG_01091 4.2e-109 comK K Competence transcription factor
HMGFFLMG_01092 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
HMGFFLMG_01093 7.8e-42 yhjA S Excalibur calcium-binding domain
HMGFFLMG_01094 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMGFFLMG_01095 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HMGFFLMG_01096 5e-60 yhjD
HMGFFLMG_01097 9.1e-110 yhjE S SNARE associated Golgi protein
HMGFFLMG_01098 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HMGFFLMG_01099 1.1e-286 yhjG CH FAD binding domain
HMGFFLMG_01100 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HMGFFLMG_01101 6.9e-215 glcP G Major Facilitator Superfamily
HMGFFLMG_01102 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HMGFFLMG_01103 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HMGFFLMG_01104 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HMGFFLMG_01105 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
HMGFFLMG_01106 3.8e-202 abrB S membrane
HMGFFLMG_01107 3.1e-215 EGP Transmembrane secretion effector
HMGFFLMG_01108 0.0 S Sugar transport-related sRNA regulator N-term
HMGFFLMG_01109 2e-36 yhjQ C COG1145 Ferredoxin
HMGFFLMG_01110 2.2e-78 yhjR S Rubrerythrin
HMGFFLMG_01111 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HMGFFLMG_01112 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMGFFLMG_01113 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMGFFLMG_01114 0.0 sbcC L COG0419 ATPase involved in DNA repair
HMGFFLMG_01115 6e-51 yisB V COG1403 Restriction endonuclease
HMGFFLMG_01116 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HMGFFLMG_01117 3e-66 gerPE S Spore germination protein GerPE
HMGFFLMG_01118 6.3e-24 gerPD S Spore germination protein
HMGFFLMG_01119 1.8e-54 gerPC S Spore germination protein
HMGFFLMG_01120 4e-34 gerPB S cell differentiation
HMGFFLMG_01121 1.9e-33 gerPA S Spore germination protein
HMGFFLMG_01122 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HMGFFLMG_01123 1.7e-176 cotH M Spore Coat
HMGFFLMG_01124 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HMGFFLMG_01125 3e-57 yisL S UPF0344 protein
HMGFFLMG_01126 0.0 wprA O Belongs to the peptidase S8 family
HMGFFLMG_01127 7.2e-106 yisN S Protein of unknown function (DUF2777)
HMGFFLMG_01128 0.0 asnO 6.3.5.4 E Asparagine synthase
HMGFFLMG_01129 2.1e-88 yizA S Damage-inducible protein DinB
HMGFFLMG_01130 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HMGFFLMG_01131 4e-243 yisQ V Mate efflux family protein
HMGFFLMG_01132 1.4e-161 yisR K Transcriptional regulator
HMGFFLMG_01133 2.4e-184 purR K helix_turn _helix lactose operon repressor
HMGFFLMG_01134 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HMGFFLMG_01135 1.3e-93 yisT S DinB family
HMGFFLMG_01136 6.4e-108 argO S Lysine exporter protein LysE YggA
HMGFFLMG_01137 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HMGFFLMG_01138 4e-36 mcbG S Pentapeptide repeats (9 copies)
HMGFFLMG_01139 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMGFFLMG_01140 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HMGFFLMG_01141 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HMGFFLMG_01142 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HMGFFLMG_01143 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
HMGFFLMG_01144 1.9e-141 yitD 4.4.1.19 S synthase
HMGFFLMG_01145 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMGFFLMG_01146 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HMGFFLMG_01147 4e-229 yitG EGP Major facilitator Superfamily
HMGFFLMG_01148 1.8e-161 yitH K Acetyltransferase (GNAT) domain
HMGFFLMG_01149 2e-82 yjcF S Acetyltransferase (GNAT) domain
HMGFFLMG_01150 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HMGFFLMG_01151 8.6e-55 yajQ S Belongs to the UPF0234 family
HMGFFLMG_01152 4e-161 cvfB S protein conserved in bacteria
HMGFFLMG_01153 8.5e-94
HMGFFLMG_01154 2.2e-125
HMGFFLMG_01155 1.5e-97 S Sporulation delaying protein SdpA
HMGFFLMG_01156 1.5e-58 K Transcriptional regulator PadR-like family
HMGFFLMG_01157 2e-95
HMGFFLMG_01158 1.4e-44 yitR S Domain of unknown function (DUF3784)
HMGFFLMG_01159 2.2e-311 nprB 3.4.24.28 E Peptidase M4
HMGFFLMG_01160 8.4e-159 yitS S protein conserved in bacteria
HMGFFLMG_01161 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HMGFFLMG_01162 1.9e-72 ipi S Intracellular proteinase inhibitor
HMGFFLMG_01163 1.2e-17 S Protein of unknown function (DUF3813)
HMGFFLMG_01164 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HMGFFLMG_01165 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HMGFFLMG_01166 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HMGFFLMG_01167 1.5e-22 pilT S Proteolipid membrane potential modulator
HMGFFLMG_01168 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
HMGFFLMG_01169 1.7e-88 norB G Major Facilitator Superfamily
HMGFFLMG_01170 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMGFFLMG_01171 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMGFFLMG_01172 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HMGFFLMG_01173 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HMGFFLMG_01174 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMGFFLMG_01175 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HMGFFLMG_01176 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMGFFLMG_01177 9.5e-28 yjzC S YjzC-like protein
HMGFFLMG_01178 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HMGFFLMG_01179 6.2e-142 yjaU I carboxylic ester hydrolase activity
HMGFFLMG_01180 7.3e-103 yjaV
HMGFFLMG_01181 1.1e-183 med S Transcriptional activator protein med
HMGFFLMG_01182 7.3e-26 comZ S ComZ
HMGFFLMG_01183 2.7e-22 yjzB
HMGFFLMG_01184 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMGFFLMG_01185 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMGFFLMG_01186 7.8e-151 yjaZ O Zn-dependent protease
HMGFFLMG_01187 1.8e-184 appD P Belongs to the ABC transporter superfamily
HMGFFLMG_01188 6.5e-187 appF E Belongs to the ABC transporter superfamily
HMGFFLMG_01189 3.5e-48 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HMGFFLMG_01190 1.9e-190 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HMGFFLMG_01191 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMGFFLMG_01192 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMGFFLMG_01193 5e-147 yjbA S Belongs to the UPF0736 family
HMGFFLMG_01194 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HMGFFLMG_01195 0.0 oppA E ABC transporter substrate-binding protein
HMGFFLMG_01196 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMGFFLMG_01197 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMGFFLMG_01198 3e-198 oppD P Belongs to the ABC transporter superfamily
HMGFFLMG_01199 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HMGFFLMG_01200 8.6e-196 yjbB EGP Major Facilitator Superfamily
HMGFFLMG_01201 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMGFFLMG_01202 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMGFFLMG_01203 6e-112 yjbE P Integral membrane protein TerC family
HMGFFLMG_01204 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HMGFFLMG_01205 2.3e-223 yjbF S Competence protein
HMGFFLMG_01206 0.0 pepF E oligoendopeptidase F
HMGFFLMG_01207 1.8e-20
HMGFFLMG_01209 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HMGFFLMG_01210 3.7e-72 yjbI S Bacterial-like globin
HMGFFLMG_01211 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HMGFFLMG_01212 2.4e-101 yjbK S protein conserved in bacteria
HMGFFLMG_01213 7.1e-62 yjbL S Belongs to the UPF0738 family
HMGFFLMG_01214 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HMGFFLMG_01215 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMGFFLMG_01216 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMGFFLMG_01217 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HMGFFLMG_01218 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMGFFLMG_01219 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HMGFFLMG_01220 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HMGFFLMG_01221 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
HMGFFLMG_01222 3e-30 thiS H thiamine diphosphate biosynthetic process
HMGFFLMG_01223 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HMGFFLMG_01224 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HMGFFLMG_01225 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMGFFLMG_01226 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HMGFFLMG_01227 5.9e-54 yjbX S Spore coat protein
HMGFFLMG_01228 5.2e-83 cotZ S Spore coat protein
HMGFFLMG_01229 3.4e-96 cotY S Spore coat protein Z
HMGFFLMG_01230 6.4e-77 cotX S Spore Coat Protein X and V domain
HMGFFLMG_01231 3e-32 cotW
HMGFFLMG_01232 2.3e-55 cotV S Spore Coat Protein X and V domain
HMGFFLMG_01233 8.7e-57 yjcA S Protein of unknown function (DUF1360)
HMGFFLMG_01236 2.9e-38 spoVIF S Stage VI sporulation protein F
HMGFFLMG_01237 0.0 yjcD 3.6.4.12 L DNA helicase
HMGFFLMG_01238 1.7e-38
HMGFFLMG_01239 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMGFFLMG_01240 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HMGFFLMG_01241 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
HMGFFLMG_01242 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMGFFLMG_01243 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMGFFLMG_01244 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
HMGFFLMG_01245 1.1e-212 yjcL S Protein of unknown function (DUF819)
HMGFFLMG_01248 2.1e-190 S Putative amidase domain
HMGFFLMG_01249 2.6e-44 yjcN
HMGFFLMG_01252 8.5e-81 L Transposase
HMGFFLMG_01253 1.6e-72 yjcP
HMGFFLMG_01254 4.1e-49 S YjcQ protein
HMGFFLMG_01255 1.1e-92 yqaS L DNA packaging
HMGFFLMG_01256 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
HMGFFLMG_01257 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
HMGFFLMG_01259 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HMGFFLMG_01260 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HMGFFLMG_01261 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMGFFLMG_01262 4.8e-51 yjdF S Protein of unknown function (DUF2992)
HMGFFLMG_01263 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HMGFFLMG_01265 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMGFFLMG_01266 4.2e-29 S Domain of unknown function (DUF4177)
HMGFFLMG_01267 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HMGFFLMG_01268 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HMGFFLMG_01270 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HMGFFLMG_01271 5.5e-83 S Protein of unknown function (DUF2690)
HMGFFLMG_01272 3.6e-21 yjfB S Putative motility protein
HMGFFLMG_01273 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
HMGFFLMG_01274 1.2e-45 T PhoQ Sensor
HMGFFLMG_01275 8.9e-104 yjgB S Domain of unknown function (DUF4309)
HMGFFLMG_01276 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HMGFFLMG_01277 4.3e-95 yjgD S Protein of unknown function (DUF1641)
HMGFFLMG_01278 8.7e-07 S Domain of unknown function (DUF4352)
HMGFFLMG_01279 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HMGFFLMG_01281 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HMGFFLMG_01282 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HMGFFLMG_01283 8.2e-30
HMGFFLMG_01284 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HMGFFLMG_01285 1.9e-122 ybbM S transport system, permease component
HMGFFLMG_01286 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HMGFFLMG_01287 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
HMGFFLMG_01288 2.8e-93 yjlB S Cupin domain
HMGFFLMG_01289 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HMGFFLMG_01290 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HMGFFLMG_01291 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
HMGFFLMG_01292 5.8e-250 yjmB G symporter YjmB
HMGFFLMG_01293 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HMGFFLMG_01294 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HMGFFLMG_01295 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HMGFFLMG_01296 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_01297 3.7e-227 exuT G Sugar (and other) transporter
HMGFFLMG_01298 2.3e-184 exuR K transcriptional
HMGFFLMG_01299 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HMGFFLMG_01300 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HMGFFLMG_01301 4.3e-130 MA20_18170 S membrane transporter protein
HMGFFLMG_01302 3.3e-80 yjoA S DinB family
HMGFFLMG_01303 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HMGFFLMG_01304 2.1e-213 S response regulator aspartate phosphatase
HMGFFLMG_01306 6.3e-41 S YCII-related domain
HMGFFLMG_01307 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HMGFFLMG_01308 2.1e-61 yjqA S Bacterial PH domain
HMGFFLMG_01309 4.2e-112 yjqB S Pfam:DUF867
HMGFFLMG_01310 4.4e-160 ydbD P Catalase
HMGFFLMG_01311 1.6e-111 xkdA E IrrE N-terminal-like domain
HMGFFLMG_01312 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HMGFFLMG_01314 5.9e-157 xkdB K sequence-specific DNA binding
HMGFFLMG_01315 6.4e-119 xkdC L Bacterial dnaA protein
HMGFFLMG_01318 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HMGFFLMG_01319 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HMGFFLMG_01320 4.8e-140 xtmA L phage terminase small subunit
HMGFFLMG_01321 9.6e-255 xtmB S phage terminase, large subunit
HMGFFLMG_01322 5.4e-286 yqbA S portal protein
HMGFFLMG_01323 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HMGFFLMG_01324 5.8e-169 xkdG S Phage capsid family
HMGFFLMG_01325 5.5e-65 yqbG S Protein of unknown function (DUF3199)
HMGFFLMG_01326 8.7e-65 yqbH S Domain of unknown function (DUF3599)
HMGFFLMG_01327 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HMGFFLMG_01328 1.9e-77 xkdJ
HMGFFLMG_01329 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HMGFFLMG_01330 6.1e-76 xkdM S Phage tail tube protein
HMGFFLMG_01331 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HMGFFLMG_01332 0.0 xkdO L Transglycosylase SLT domain
HMGFFLMG_01333 3.7e-122 xkdP S Lysin motif
HMGFFLMG_01334 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HMGFFLMG_01335 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HMGFFLMG_01336 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HMGFFLMG_01337 1.2e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HMGFFLMG_01338 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HMGFFLMG_01339 6.7e-41
HMGFFLMG_01340 0.0
HMGFFLMG_01341 2.6e-55 xkdW S XkdW protein
HMGFFLMG_01342 1.7e-23 xkdX
HMGFFLMG_01343 1.2e-154 xepA
HMGFFLMG_01344 2.8e-39 xhlA S Haemolysin XhlA
HMGFFLMG_01345 9.3e-40 xhlB S SPP1 phage holin
HMGFFLMG_01346 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMGFFLMG_01347 6.7e-23 spoIISB S Stage II sporulation protein SB
HMGFFLMG_01348 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HMGFFLMG_01349 5.8e-175 pit P phosphate transporter
HMGFFLMG_01350 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HMGFFLMG_01351 9.4e-242 steT E amino acid
HMGFFLMG_01352 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HMGFFLMG_01354 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMGFFLMG_01355 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HMGFFLMG_01357 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMGFFLMG_01358 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HMGFFLMG_01359 7.9e-154 dppA E D-aminopeptidase
HMGFFLMG_01360 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMGFFLMG_01361 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMGFFLMG_01362 3.4e-191 dppD P Belongs to the ABC transporter superfamily
HMGFFLMG_01363 0.0 dppE E ABC transporter substrate-binding protein
HMGFFLMG_01365 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HMGFFLMG_01366 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HMGFFLMG_01367 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HMGFFLMG_01368 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
HMGFFLMG_01369 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
HMGFFLMG_01370 5.3e-161 ykgA E Amidinotransferase
HMGFFLMG_01371 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HMGFFLMG_01372 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HMGFFLMG_01373 1e-07
HMGFFLMG_01374 5.4e-130 ykjA S Protein of unknown function (DUF421)
HMGFFLMG_01375 1e-98 ykkA S Protein of unknown function (DUF664)
HMGFFLMG_01376 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMGFFLMG_01377 3.5e-55 ykkC P Multidrug resistance protein
HMGFFLMG_01378 1.1e-50 ykkD P Multidrug resistance protein
HMGFFLMG_01379 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HMGFFLMG_01380 1.3e-31 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMGFFLMG_01381 4.9e-19 rom S Rop protein
HMGFFLMG_01382 2.9e-63 mbeC S Psort location Cytoplasmic, score
HMGFFLMG_01383 1.2e-214 tetA EGP Sugar (and other) transporter
HMGFFLMG_01384 1.2e-242 tetL EGP Major Facilitator Superfamily
HMGFFLMG_01385 2e-160 penP 3.5.2.6 V Beta-lactamase
HMGFFLMG_01386 6.6e-162 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMGFFLMG_01387 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMGFFLMG_01388 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HMGFFLMG_01389 3.9e-75 ohrR K COG1846 Transcriptional regulators
HMGFFLMG_01390 8.4e-72 ohrB O Organic hydroperoxide resistance protein
HMGFFLMG_01392 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HMGFFLMG_01393 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HMGFFLMG_01394 1.7e-176 isp O Belongs to the peptidase S8 family
HMGFFLMG_01395 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMGFFLMG_01396 1.8e-136 ykoC P Cobalt transport protein
HMGFFLMG_01397 4.6e-311 P ABC transporter, ATP-binding protein
HMGFFLMG_01398 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HMGFFLMG_01399 7.9e-111 ykoF S YKOF-related Family
HMGFFLMG_01400 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_01401 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
HMGFFLMG_01402 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
HMGFFLMG_01403 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
HMGFFLMG_01406 2.2e-222 mgtE P Acts as a magnesium transporter
HMGFFLMG_01407 1.4e-53 tnrA K transcriptional
HMGFFLMG_01408 5.9e-18
HMGFFLMG_01409 6.9e-26 ykoL
HMGFFLMG_01410 1.3e-81 mhqR K transcriptional
HMGFFLMG_01411 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HMGFFLMG_01412 3.7e-99 ykoP G polysaccharide deacetylase
HMGFFLMG_01413 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HMGFFLMG_01414 0.0 ykoS
HMGFFLMG_01415 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HMGFFLMG_01416 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HMGFFLMG_01417 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HMGFFLMG_01418 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HMGFFLMG_01419 1.4e-116 ykoX S membrane-associated protein
HMGFFLMG_01420 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HMGFFLMG_01421 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMGFFLMG_01422 8.2e-117 rsgI S Anti-sigma factor N-terminus
HMGFFLMG_01423 1.9e-26 sspD S small acid-soluble spore protein
HMGFFLMG_01424 1.5e-124 ykrK S Domain of unknown function (DUF1836)
HMGFFLMG_01425 7e-156 htpX O Belongs to the peptidase M48B family
HMGFFLMG_01426 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HMGFFLMG_01427 1.2e-10 ydfR S Protein of unknown function (DUF421)
HMGFFLMG_01428 4.5e-22 ykzE
HMGFFLMG_01429 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HMGFFLMG_01430 0.0 kinE 2.7.13.3 T Histidine kinase
HMGFFLMG_01431 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMGFFLMG_01433 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HMGFFLMG_01434 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HMGFFLMG_01435 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HMGFFLMG_01436 8e-232 mtnE 2.6.1.83 E Aminotransferase
HMGFFLMG_01437 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HMGFFLMG_01438 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HMGFFLMG_01439 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HMGFFLMG_01440 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HMGFFLMG_01441 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HMGFFLMG_01442 6.4e-09 S Spo0E like sporulation regulatory protein
HMGFFLMG_01443 1.4e-64 eag
HMGFFLMG_01444 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HMGFFLMG_01445 1.3e-75 ykvE K transcriptional
HMGFFLMG_01446 2.5e-125 motB N Flagellar motor protein
HMGFFLMG_01447 2.7e-138 motA N flagellar motor
HMGFFLMG_01448 0.0 clpE O Belongs to the ClpA ClpB family
HMGFFLMG_01449 8.7e-182 ykvI S membrane
HMGFFLMG_01450 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HMGFFLMG_01451 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HMGFFLMG_01452 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HMGFFLMG_01453 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HMGFFLMG_01454 2e-61 ykvN K Transcriptional regulator
HMGFFLMG_01455 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
HMGFFLMG_01456 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
HMGFFLMG_01457 1.2e-35 3.5.1.104 M LysM domain
HMGFFLMG_01458 8.5e-133 G Glycosyl hydrolases family 18
HMGFFLMG_01459 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HMGFFLMG_01460 6e-25 ykvS S protein conserved in bacteria
HMGFFLMG_01461 2.8e-28
HMGFFLMG_01462 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
HMGFFLMG_01463 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMGFFLMG_01464 4.9e-90 stoA CO thiol-disulfide
HMGFFLMG_01465 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HMGFFLMG_01466 3.8e-09
HMGFFLMG_01467 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HMGFFLMG_01469 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
HMGFFLMG_01471 4.5e-128 glcT K antiterminator
HMGFFLMG_01472 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMGFFLMG_01473 2.1e-39 ptsH G phosphocarrier protein HPr
HMGFFLMG_01474 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMGFFLMG_01475 7.2e-39 splA S Transcriptional regulator
HMGFFLMG_01476 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
HMGFFLMG_01477 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMGFFLMG_01478 2e-264 mcpC NT chemotaxis protein
HMGFFLMG_01479 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HMGFFLMG_01480 8e-124 ykwD J protein with SCP PR1 domains
HMGFFLMG_01481 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HMGFFLMG_01482 0.0 pilS 2.7.13.3 T Histidine kinase
HMGFFLMG_01483 8e-224 patA 2.6.1.1 E Aminotransferase
HMGFFLMG_01484 2.2e-15
HMGFFLMG_01485 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HMGFFLMG_01486 1.7e-84 ykyB S YkyB-like protein
HMGFFLMG_01487 1.6e-238 ykuC EGP Major facilitator Superfamily
HMGFFLMG_01488 4.6e-88 ykuD S protein conserved in bacteria
HMGFFLMG_01489 9.4e-166 ykuE S Metallophosphoesterase
HMGFFLMG_01490 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMGFFLMG_01491 0.0 3.2.1.132 M Putative peptidoglycan binding domain
HMGFFLMG_01492 1.7e-93 M Peptidoglycan-binding domain 1 protein
HMGFFLMG_01494 5.2e-234 ykuI T Diguanylate phosphodiesterase
HMGFFLMG_01495 3.9e-37 ykuJ S protein conserved in bacteria
HMGFFLMG_01496 4.4e-94 ykuK S Ribonuclease H-like
HMGFFLMG_01497 3.9e-27 ykzF S Antirepressor AbbA
HMGFFLMG_01498 1.6e-76 ykuL S CBS domain
HMGFFLMG_01499 3.5e-168 ccpC K Transcriptional regulator
HMGFFLMG_01500 5.7e-88 fld C Flavodoxin domain
HMGFFLMG_01501 3.2e-177 ykuO
HMGFFLMG_01502 3.2e-80 fld C Flavodoxin
HMGFFLMG_01503 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMGFFLMG_01504 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMGFFLMG_01505 9e-37 ykuS S Belongs to the UPF0180 family
HMGFFLMG_01506 8.8e-142 ykuT M Mechanosensitive ion channel
HMGFFLMG_01507 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HMGFFLMG_01508 4.4e-82 ykuV CO thiol-disulfide
HMGFFLMG_01509 5.8e-95 rok K Repressor of ComK
HMGFFLMG_01510 2.9e-147 yknT
HMGFFLMG_01511 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HMGFFLMG_01512 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HMGFFLMG_01513 8.1e-246 moeA 2.10.1.1 H molybdopterin
HMGFFLMG_01514 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HMGFFLMG_01515 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HMGFFLMG_01516 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HMGFFLMG_01517 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HMGFFLMG_01518 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HMGFFLMG_01519 1e-117 yknW S Yip1 domain
HMGFFLMG_01520 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMGFFLMG_01521 2.5e-124 macB V ABC transporter, ATP-binding protein
HMGFFLMG_01522 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HMGFFLMG_01523 3.1e-136 fruR K Transcriptional regulator
HMGFFLMG_01524 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HMGFFLMG_01525 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HMGFFLMG_01526 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HMGFFLMG_01527 8.1e-39 ykoA
HMGFFLMG_01528 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HMGFFLMG_01529 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMGFFLMG_01530 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HMGFFLMG_01531 1.1e-12 S Uncharacterized protein YkpC
HMGFFLMG_01532 7.7e-183 mreB D Rod-share determining protein MreBH
HMGFFLMG_01533 1.5e-43 abrB K of stationary sporulation gene expression
HMGFFLMG_01534 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HMGFFLMG_01535 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HMGFFLMG_01536 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HMGFFLMG_01537 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HMGFFLMG_01538 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMGFFLMG_01539 8.2e-31 ykzG S Belongs to the UPF0356 family
HMGFFLMG_01540 1.4e-147 ykrA S hydrolases of the HAD superfamily
HMGFFLMG_01541 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMGFFLMG_01543 2e-115 recN L Putative cell-wall binding lipoprotein
HMGFFLMG_01544 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HMGFFLMG_01545 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMGFFLMG_01546 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMGFFLMG_01547 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HMGFFLMG_01548 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HMGFFLMG_01549 3.5e-277 speA 4.1.1.19 E Arginine
HMGFFLMG_01550 1.6e-42 yktA S Belongs to the UPF0223 family
HMGFFLMG_01551 7.1e-118 yktB S Belongs to the UPF0637 family
HMGFFLMG_01552 7.1e-26 ykzI
HMGFFLMG_01553 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HMGFFLMG_01554 6.9e-78 ykzC S Acetyltransferase (GNAT) family
HMGFFLMG_01555 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HMGFFLMG_01556 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HMGFFLMG_01557 0.0 ylaA
HMGFFLMG_01558 2.7e-42 ylaB
HMGFFLMG_01559 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_01560 1.2e-11 sigC S Putative zinc-finger
HMGFFLMG_01561 1.8e-38 ylaE
HMGFFLMG_01562 8.2e-22 S Family of unknown function (DUF5325)
HMGFFLMG_01563 0.0 typA T GTP-binding protein TypA
HMGFFLMG_01564 4.2e-47 ylaH S YlaH-like protein
HMGFFLMG_01565 2.5e-32 ylaI S protein conserved in bacteria
HMGFFLMG_01566 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMGFFLMG_01567 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HMGFFLMG_01568 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HMGFFLMG_01569 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HMGFFLMG_01570 8.7e-44 ylaN S Belongs to the UPF0358 family
HMGFFLMG_01571 4.5e-214 ftsW D Belongs to the SEDS family
HMGFFLMG_01572 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMGFFLMG_01573 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HMGFFLMG_01574 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HMGFFLMG_01575 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HMGFFLMG_01576 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HMGFFLMG_01577 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HMGFFLMG_01578 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HMGFFLMG_01579 3e-167 ctaG S cytochrome c oxidase
HMGFFLMG_01580 7e-62 ylbA S YugN-like family
HMGFFLMG_01581 2.6e-74 ylbB T COG0517 FOG CBS domain
HMGFFLMG_01582 3e-201 ylbC S protein with SCP PR1 domains
HMGFFLMG_01583 4.1e-63 ylbD S Putative coat protein
HMGFFLMG_01584 6.7e-37 ylbE S YlbE-like protein
HMGFFLMG_01585 1.8e-75 ylbF S Belongs to the UPF0342 family
HMGFFLMG_01586 7.5e-39 ylbG S UPF0298 protein
HMGFFLMG_01587 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
HMGFFLMG_01588 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMGFFLMG_01589 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
HMGFFLMG_01590 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HMGFFLMG_01591 6.8e-187 ylbL T Belongs to the peptidase S16 family
HMGFFLMG_01592 2.8e-235 ylbM S Belongs to the UPF0348 family
HMGFFLMG_01594 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HMGFFLMG_01595 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMGFFLMG_01596 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HMGFFLMG_01597 4e-89 ylbP K n-acetyltransferase
HMGFFLMG_01598 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMGFFLMG_01599 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HMGFFLMG_01600 2.9e-78 mraZ K Belongs to the MraZ family
HMGFFLMG_01601 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMGFFLMG_01602 3.7e-44 ftsL D Essential cell division protein
HMGFFLMG_01603 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HMGFFLMG_01604 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HMGFFLMG_01605 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMGFFLMG_01606 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMGFFLMG_01607 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMGFFLMG_01608 5.7e-186 spoVE D Belongs to the SEDS family
HMGFFLMG_01609 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMGFFLMG_01610 5.3e-167 murB 1.3.1.98 M cell wall formation
HMGFFLMG_01611 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMGFFLMG_01612 2.4e-103 ylxW S protein conserved in bacteria
HMGFFLMG_01613 1e-102 ylxX S protein conserved in bacteria
HMGFFLMG_01614 6.2e-58 sbp S small basic protein
HMGFFLMG_01615 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMGFFLMG_01616 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMGFFLMG_01617 0.0 bpr O COG1404 Subtilisin-like serine proteases
HMGFFLMG_01618 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HMGFFLMG_01619 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMGFFLMG_01620 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMGFFLMG_01621 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HMGFFLMG_01622 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
HMGFFLMG_01623 2.4e-37 ylmC S sporulation protein
HMGFFLMG_01624 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HMGFFLMG_01625 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HMGFFLMG_01626 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMGFFLMG_01627 1.3e-39 yggT S membrane
HMGFFLMG_01628 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HMGFFLMG_01629 2.6e-67 divIVA D Cell division initiation protein
HMGFFLMG_01630 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMGFFLMG_01631 1.3e-63 dksA T COG1734 DnaK suppressor protein
HMGFFLMG_01632 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMGFFLMG_01633 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMGFFLMG_01634 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMGFFLMG_01635 9e-232 pyrP F Xanthine uracil
HMGFFLMG_01636 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMGFFLMG_01637 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMGFFLMG_01638 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMGFFLMG_01639 0.0 carB 6.3.5.5 F Belongs to the CarB family
HMGFFLMG_01640 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HMGFFLMG_01641 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMGFFLMG_01642 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMGFFLMG_01643 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMGFFLMG_01645 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HMGFFLMG_01646 1.1e-179 cysP P phosphate transporter
HMGFFLMG_01647 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HMGFFLMG_01648 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HMGFFLMG_01649 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HMGFFLMG_01650 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HMGFFLMG_01651 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HMGFFLMG_01652 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HMGFFLMG_01653 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HMGFFLMG_01654 2.4e-156 yloC S stress-induced protein
HMGFFLMG_01655 1.5e-40 ylzA S Belongs to the UPF0296 family
HMGFFLMG_01656 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HMGFFLMG_01657 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMGFFLMG_01658 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMGFFLMG_01659 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMGFFLMG_01660 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMGFFLMG_01661 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMGFFLMG_01662 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMGFFLMG_01663 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HMGFFLMG_01664 2.4e-141 stp 3.1.3.16 T phosphatase
HMGFFLMG_01665 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HMGFFLMG_01666 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMGFFLMG_01667 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMGFFLMG_01668 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMGFFLMG_01669 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMGFFLMG_01670 5.5e-59 asp S protein conserved in bacteria
HMGFFLMG_01671 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
HMGFFLMG_01672 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HMGFFLMG_01673 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HMGFFLMG_01674 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMGFFLMG_01675 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HMGFFLMG_01676 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMGFFLMG_01677 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HMGFFLMG_01678 6.1e-129 IQ reductase
HMGFFLMG_01679 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMGFFLMG_01680 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMGFFLMG_01681 0.0 smc D Required for chromosome condensation and partitioning
HMGFFLMG_01682 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMGFFLMG_01683 2.9e-87
HMGFFLMG_01684 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMGFFLMG_01685 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMGFFLMG_01686 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMGFFLMG_01687 1.2e-36 ylqC S Belongs to the UPF0109 family
HMGFFLMG_01688 1.3e-61 ylqD S YlqD protein
HMGFFLMG_01689 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMGFFLMG_01690 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMGFFLMG_01691 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMGFFLMG_01692 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMGFFLMG_01693 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMGFFLMG_01694 8.5e-291 ylqG
HMGFFLMG_01695 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HMGFFLMG_01696 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HMGFFLMG_01697 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HMGFFLMG_01698 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HMGFFLMG_01699 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMGFFLMG_01700 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMGFFLMG_01701 2.5e-169 xerC L tyrosine recombinase XerC
HMGFFLMG_01702 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMGFFLMG_01703 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMGFFLMG_01704 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HMGFFLMG_01705 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HMGFFLMG_01706 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
HMGFFLMG_01707 1.9e-31 fliE N Flagellar hook-basal body
HMGFFLMG_01708 2.4e-255 fliF N The M ring may be actively involved in energy transduction
HMGFFLMG_01709 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HMGFFLMG_01710 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HMGFFLMG_01711 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HMGFFLMG_01712 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HMGFFLMG_01713 7.7e-37 ylxF S MgtE intracellular N domain
HMGFFLMG_01714 1.2e-221 fliK N Flagellar hook-length control protein
HMGFFLMG_01715 1.7e-72 flgD N Flagellar basal body rod modification protein
HMGFFLMG_01716 8.2e-140 flgG N Flagellar basal body rod
HMGFFLMG_01717 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HMGFFLMG_01718 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HMGFFLMG_01719 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HMGFFLMG_01720 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HMGFFLMG_01721 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
HMGFFLMG_01722 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HMGFFLMG_01723 2.2e-36 fliQ N Role in flagellar biosynthesis
HMGFFLMG_01724 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HMGFFLMG_01725 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HMGFFLMG_01726 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HMGFFLMG_01727 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
HMGFFLMG_01728 7.5e-158 flhG D Belongs to the ParA family
HMGFFLMG_01729 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HMGFFLMG_01730 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HMGFFLMG_01731 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HMGFFLMG_01732 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HMGFFLMG_01733 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HMGFFLMG_01734 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMGFFLMG_01735 4.3e-78 ylxL
HMGFFLMG_01736 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HMGFFLMG_01737 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMGFFLMG_01738 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMGFFLMG_01739 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMGFFLMG_01740 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMGFFLMG_01741 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HMGFFLMG_01742 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HMGFFLMG_01743 7.7e-233 rasP M zinc metalloprotease
HMGFFLMG_01744 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMGFFLMG_01745 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMGFFLMG_01746 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HMGFFLMG_01747 1.1e-203 nusA K Participates in both transcription termination and antitermination
HMGFFLMG_01748 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HMGFFLMG_01749 3.1e-47 ylxQ J ribosomal protein
HMGFFLMG_01750 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMGFFLMG_01751 3e-44 ylxP S protein conserved in bacteria
HMGFFLMG_01752 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMGFFLMG_01753 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMGFFLMG_01754 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMGFFLMG_01755 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMGFFLMG_01756 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HMGFFLMG_01757 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HMGFFLMG_01758 4.4e-233 pepR S Belongs to the peptidase M16 family
HMGFFLMG_01759 2.6e-42 ymxH S YlmC YmxH family
HMGFFLMG_01760 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HMGFFLMG_01761 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HMGFFLMG_01762 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMGFFLMG_01763 3.8e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HMGFFLMG_01764 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMGFFLMG_01765 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMGFFLMG_01766 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HMGFFLMG_01767 4.4e-32 S YlzJ-like protein
HMGFFLMG_01768 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMGFFLMG_01769 1.4e-133 ymfC K Transcriptional regulator
HMGFFLMG_01770 1.5e-206 ymfD EGP Major facilitator Superfamily
HMGFFLMG_01771 2.6e-236 ymfF S Peptidase M16
HMGFFLMG_01772 1.4e-242 ymfH S zinc protease
HMGFFLMG_01773 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HMGFFLMG_01774 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HMGFFLMG_01775 2.4e-76 ymfK S Protein of unknown function (DUF3388)
HMGFFLMG_01776 3.1e-53 ymfK S Protein of unknown function (DUF3388)
HMGFFLMG_01777 1.9e-124 ymfM S protein conserved in bacteria
HMGFFLMG_01778 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMGFFLMG_01779 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
HMGFFLMG_01780 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMGFFLMG_01781 1e-215 pbpX V Beta-lactamase
HMGFFLMG_01782 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HMGFFLMG_01783 1.9e-152 ymdB S protein conserved in bacteria
HMGFFLMG_01784 1.2e-36 spoVS S Stage V sporulation protein S
HMGFFLMG_01785 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HMGFFLMG_01786 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HMGFFLMG_01787 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HMGFFLMG_01788 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HMGFFLMG_01789 2.2e-88 cotE S Spore coat protein
HMGFFLMG_01790 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMGFFLMG_01791 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMGFFLMG_01792 2.3e-70 S Regulatory protein YrvL
HMGFFLMG_01794 1.2e-97 ymcC S Membrane
HMGFFLMG_01795 4.4e-109 pksA K Transcriptional regulator
HMGFFLMG_01796 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HMGFFLMG_01797 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HMGFFLMG_01799 2.4e-186 pksD Q Acyl transferase domain
HMGFFLMG_01800 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HMGFFLMG_01801 1.4e-37 acpK IQ Phosphopantetheine attachment site
HMGFFLMG_01802 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMGFFLMG_01803 1.3e-245 pksG 2.3.3.10 I synthase
HMGFFLMG_01804 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
HMGFFLMG_01805 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HMGFFLMG_01806 0.0 rhiB IQ polyketide synthase
HMGFFLMG_01807 0.0 pfaA Q Polyketide synthase of type I
HMGFFLMG_01808 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HMGFFLMG_01809 0.0 dhbF IQ polyketide synthase
HMGFFLMG_01810 0.0 dhbF IQ polyketide synthase
HMGFFLMG_01811 0.0 pks13 HQ Beta-ketoacyl synthase
HMGFFLMG_01812 2.5e-233 cypA C Cytochrome P450
HMGFFLMG_01813 1.2e-61 ymzB
HMGFFLMG_01814 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
HMGFFLMG_01815 4.6e-252 aprX O Belongs to the peptidase S8 family
HMGFFLMG_01816 2.1e-126 ymaC S Replication protein
HMGFFLMG_01817 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
HMGFFLMG_01818 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HMGFFLMG_01819 4.9e-51 ebrA P Small Multidrug Resistance protein
HMGFFLMG_01821 2.1e-46 ymaF S YmaF family
HMGFFLMG_01822 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMGFFLMG_01823 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HMGFFLMG_01824 6.3e-23
HMGFFLMG_01825 4.5e-22 ymzA
HMGFFLMG_01826 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HMGFFLMG_01827 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMGFFLMG_01828 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMGFFLMG_01829 2e-109 ymaB
HMGFFLMG_01830 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMGFFLMG_01831 1.7e-176 spoVK O stage V sporulation protein K
HMGFFLMG_01832 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMGFFLMG_01833 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HMGFFLMG_01834 1.1e-68 glnR K transcriptional
HMGFFLMG_01835 7e-261 glnA 6.3.1.2 E glutamine synthetase
HMGFFLMG_01836 5e-10
HMGFFLMG_01837 2.5e-32
HMGFFLMG_01838 5.8e-39
HMGFFLMG_01839 6.8e-80 G regulation of fungal-type cell wall biogenesis
HMGFFLMG_01840 4.9e-145 ynaC
HMGFFLMG_01841 2e-99 ynaD J Acetyltransferase (GNAT) domain
HMGFFLMG_01842 1.9e-123 ynaE S Domain of unknown function (DUF3885)
HMGFFLMG_01843 6.4e-60 ynaF
HMGFFLMG_01846 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HMGFFLMG_01847 2.7e-255 xynT G MFS/sugar transport protein
HMGFFLMG_01848 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HMGFFLMG_01849 1e-215 xylR GK ROK family
HMGFFLMG_01850 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HMGFFLMG_01851 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HMGFFLMG_01852 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
HMGFFLMG_01853 3.5e-247 iolT EGP Major facilitator Superfamily
HMGFFLMG_01854 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMGFFLMG_01855 6.3e-84 yncE S Protein of unknown function (DUF2691)
HMGFFLMG_01856 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HMGFFLMG_01857 5.2e-15
HMGFFLMG_01860 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMGFFLMG_01862 1.3e-134 S Domain of unknown function, YrpD
HMGFFLMG_01865 7.9e-25 tatA U protein secretion
HMGFFLMG_01866 1.8e-71
HMGFFLMG_01867 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HMGFFLMG_01870 5.7e-286 gerAA EG Spore germination protein
HMGFFLMG_01871 4.5e-197 gerAB U Spore germination
HMGFFLMG_01872 4.2e-220 gerLC S Spore germination protein
HMGFFLMG_01873 7.7e-154 yndG S DoxX-like family
HMGFFLMG_01874 2.6e-117 yndH S Domain of unknown function (DUF4166)
HMGFFLMG_01875 0.0 yndJ S YndJ-like protein
HMGFFLMG_01877 8.6e-139 yndL S Replication protein
HMGFFLMG_01878 5.8e-74 yndM S Protein of unknown function (DUF2512)
HMGFFLMG_01879 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HMGFFLMG_01881 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMGFFLMG_01882 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HMGFFLMG_01883 9.2e-113 yneB L resolvase
HMGFFLMG_01884 1.3e-32 ynzC S UPF0291 protein
HMGFFLMG_01885 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMGFFLMG_01886 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HMGFFLMG_01887 1.8e-28 yneF S UPF0154 protein
HMGFFLMG_01888 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HMGFFLMG_01889 7.1e-127 ccdA O cytochrome c biogenesis protein
HMGFFLMG_01890 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HMGFFLMG_01891 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HMGFFLMG_01892 4.2e-74 yneK S Protein of unknown function (DUF2621)
HMGFFLMG_01893 4.1e-65 hspX O Spore coat protein
HMGFFLMG_01894 3.9e-19 sspP S Belongs to the SspP family
HMGFFLMG_01895 2.2e-14 sspO S Belongs to the SspO family
HMGFFLMG_01896 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HMGFFLMG_01897 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HMGFFLMG_01899 3.1e-08 sspN S Small acid-soluble spore protein N family
HMGFFLMG_01900 3.9e-35 tlp S Belongs to the Tlp family
HMGFFLMG_01901 1.2e-73 yneP S Thioesterase-like superfamily
HMGFFLMG_01902 1.3e-53 yneQ
HMGFFLMG_01903 4.1e-49 yneR S Belongs to the HesB IscA family
HMGFFLMG_01904 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMGFFLMG_01905 6.6e-69 yccU S CoA-binding protein
HMGFFLMG_01906 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMGFFLMG_01907 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMGFFLMG_01908 2.3e-12
HMGFFLMG_01909 1.3e-57 ynfC
HMGFFLMG_01910 8.2e-252 agcS E Sodium alanine symporter
HMGFFLMG_01911 1.1e-286 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HMGFFLMG_01913 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HMGFFLMG_01914 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HMGFFLMG_01915 2.4e-80 yngA S membrane
HMGFFLMG_01916 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMGFFLMG_01917 5.5e-104 yngC S membrane-associated protein
HMGFFLMG_01918 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
HMGFFLMG_01919 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HMGFFLMG_01920 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HMGFFLMG_01921 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HMGFFLMG_01922 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HMGFFLMG_01923 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HMGFFLMG_01924 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HMGFFLMG_01925 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HMGFFLMG_01926 1.8e-31 S Family of unknown function (DUF5367)
HMGFFLMG_01928 1.3e-306 yngK T Glycosyl hydrolase-like 10
HMGFFLMG_01929 2.8e-64 yngL S Protein of unknown function (DUF1360)
HMGFFLMG_01930 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HMGFFLMG_01931 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMGFFLMG_01932 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMGFFLMG_01933 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMGFFLMG_01934 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HMGFFLMG_01935 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
HMGFFLMG_01936 2.3e-246 yoeA V MATE efflux family protein
HMGFFLMG_01937 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HMGFFLMG_01939 2.2e-96 L Integrase
HMGFFLMG_01940 3e-34 yoeD G Helix-turn-helix domain
HMGFFLMG_01941 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HMGFFLMG_01942 2.5e-158 gltR1 K Transcriptional regulator
HMGFFLMG_01943 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HMGFFLMG_01944 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HMGFFLMG_01945 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HMGFFLMG_01946 7.8e-155 gltC K Transcriptional regulator
HMGFFLMG_01947 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMGFFLMG_01948 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMGFFLMG_01949 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HMGFFLMG_01950 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_01951 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
HMGFFLMG_01952 3.1e-144 yoxB
HMGFFLMG_01953 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HMGFFLMG_01954 6.2e-235 yoaB EGP Major facilitator Superfamily
HMGFFLMG_01955 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HMGFFLMG_01956 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMGFFLMG_01957 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMGFFLMG_01958 1.9e-33 yoaF
HMGFFLMG_01959 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
HMGFFLMG_01960 7e-14
HMGFFLMG_01961 1.5e-38 S Protein of unknown function (DUF4025)
HMGFFLMG_01962 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
HMGFFLMG_01963 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HMGFFLMG_01964 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HMGFFLMG_01965 2.3e-111 yoaK S Membrane
HMGFFLMG_01966 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HMGFFLMG_01967 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
HMGFFLMG_01969 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
HMGFFLMG_01971 1.5e-146 yoaP 3.1.3.18 K YoaP-like
HMGFFLMG_01972 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
HMGFFLMG_01973 4.1e-89
HMGFFLMG_01974 2.4e-172 yoaR V vancomycin resistance protein
HMGFFLMG_01975 4.3e-75 yoaS S Protein of unknown function (DUF2975)
HMGFFLMG_01976 4.2e-37 yozG K Transcriptional regulator
HMGFFLMG_01977 1.1e-149 yoaT S Protein of unknown function (DUF817)
HMGFFLMG_01978 8.6e-159 yoaU K LysR substrate binding domain
HMGFFLMG_01979 6e-160 yijE EG EamA-like transporter family
HMGFFLMG_01980 3.7e-78 yoaW
HMGFFLMG_01981 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HMGFFLMG_01982 2.3e-170 bla 3.5.2.6 V beta-lactamase
HMGFFLMG_01986 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HMGFFLMG_01987 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HMGFFLMG_01988 1.4e-37 S TM2 domain
HMGFFLMG_01989 5.7e-58 K Helix-turn-helix
HMGFFLMG_01991 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
HMGFFLMG_01992 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
HMGFFLMG_01993 1.8e-178 yobF
HMGFFLMG_01998 1.7e-207 S aspartate phosphatase
HMGFFLMG_02000 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMGFFLMG_02001 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMGFFLMG_02002 2.6e-38 S YolD-like protein
HMGFFLMG_02003 1.2e-49
HMGFFLMG_02004 0.0 K Psort location Cytoplasmic, score
HMGFFLMG_02005 2.7e-157 yobJ
HMGFFLMG_02006 3e-86 S SMI1-KNR4 cell-wall
HMGFFLMG_02007 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HMGFFLMG_02008 7.9e-105 yokH G SMI1 / KNR4 family
HMGFFLMG_02009 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HMGFFLMG_02010 0.0 yobO M Pectate lyase superfamily protein
HMGFFLMG_02011 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HMGFFLMG_02012 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
HMGFFLMG_02013 2.5e-143 yobR 2.3.1.1 J FR47-like protein
HMGFFLMG_02014 3e-99 yobS K Transcriptional regulator
HMGFFLMG_02015 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HMGFFLMG_02016 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
HMGFFLMG_02017 9e-178 yobV K WYL domain
HMGFFLMG_02018 2.5e-95 yobW
HMGFFLMG_02019 1e-51 czrA K transcriptional
HMGFFLMG_02020 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HMGFFLMG_02021 1.5e-92 yozB S membrane
HMGFFLMG_02022 2.2e-145
HMGFFLMG_02023 1.9e-94 yocC
HMGFFLMG_02024 6.9e-189 yocD 3.4.17.13 V peptidase S66
HMGFFLMG_02025 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HMGFFLMG_02026 3.2e-198 desK 2.7.13.3 T Histidine kinase
HMGFFLMG_02027 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMGFFLMG_02028 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HMGFFLMG_02029 0.0 recQ 3.6.4.12 L DNA helicase
HMGFFLMG_02030 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMGFFLMG_02031 3.3e-83 dksA T general stress protein
HMGFFLMG_02032 6.4e-54 yocL
HMGFFLMG_02033 6.6e-34
HMGFFLMG_02034 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HMGFFLMG_02035 1.1e-40 yozN
HMGFFLMG_02036 1.9e-36 yocN
HMGFFLMG_02037 4.2e-56 yozO S Bacterial PH domain
HMGFFLMG_02038 2.7e-31 yozC
HMGFFLMG_02039 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HMGFFLMG_02040 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HMGFFLMG_02041 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
HMGFFLMG_02042 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HMGFFLMG_02043 5.1e-168 yocS S -transporter
HMGFFLMG_02044 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HMGFFLMG_02045 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HMGFFLMG_02046 0.0 yojO P Von Willebrand factor
HMGFFLMG_02047 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
HMGFFLMG_02048 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HMGFFLMG_02049 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HMGFFLMG_02050 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HMGFFLMG_02051 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMGFFLMG_02053 4.2e-245 norM V Multidrug efflux pump
HMGFFLMG_02054 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMGFFLMG_02055 2.1e-125 yojG S deacetylase
HMGFFLMG_02056 2.2e-60 yojF S Protein of unknown function (DUF1806)
HMGFFLMG_02057 1.5e-43
HMGFFLMG_02058 3.5e-163 rarD S -transporter
HMGFFLMG_02059 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
HMGFFLMG_02060 3.4e-09
HMGFFLMG_02061 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
HMGFFLMG_02062 3.8e-66 yodA S tautomerase
HMGFFLMG_02063 1.7e-57 yodB K transcriptional
HMGFFLMG_02064 4.8e-108 yodC C nitroreductase
HMGFFLMG_02065 3.8e-113 mhqD S Carboxylesterase
HMGFFLMG_02066 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
HMGFFLMG_02067 6.2e-28 S Protein of unknown function (DUF3311)
HMGFFLMG_02068 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMGFFLMG_02069 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HMGFFLMG_02070 1.7e-128 yodH Q Methyltransferase
HMGFFLMG_02071 5.2e-24 yodI
HMGFFLMG_02072 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HMGFFLMG_02073 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HMGFFLMG_02074 5.3e-09
HMGFFLMG_02075 3.6e-54 yodL S YodL-like
HMGFFLMG_02076 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
HMGFFLMG_02077 2.8e-24 yozD S YozD-like protein
HMGFFLMG_02079 1.4e-124 yodN
HMGFFLMG_02080 1.4e-36 yozE S Belongs to the UPF0346 family
HMGFFLMG_02081 2.9e-47 yokU S YokU-like protein, putative antitoxin
HMGFFLMG_02082 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HMGFFLMG_02083 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HMGFFLMG_02084 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
HMGFFLMG_02085 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HMGFFLMG_02086 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HMGFFLMG_02087 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMGFFLMG_02090 2.9e-145 yiiD K acetyltransferase
HMGFFLMG_02091 1e-256 cgeD M maturation of the outermost layer of the spore
HMGFFLMG_02092 3.5e-38 cgeC
HMGFFLMG_02093 2.6e-65 cgeA
HMGFFLMG_02094 3.3e-188 cgeB S Spore maturation protein
HMGFFLMG_02095 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HMGFFLMG_02096 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HMGFFLMG_02097 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HMGFFLMG_02098 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMGFFLMG_02099 1.6e-70 ypoP K transcriptional
HMGFFLMG_02100 2.6e-223 mepA V MATE efflux family protein
HMGFFLMG_02101 5.5e-29 ypmT S Uncharacterized ympT
HMGFFLMG_02102 5e-99 ypmS S protein conserved in bacteria
HMGFFLMG_02103 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HMGFFLMG_02104 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HMGFFLMG_02105 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HMGFFLMG_02106 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HMGFFLMG_02107 1.6e-185 pspF K Transcriptional regulator
HMGFFLMG_02108 4.2e-110 hlyIII S protein, Hemolysin III
HMGFFLMG_02109 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HMGFFLMG_02110 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMGFFLMG_02111 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMGFFLMG_02112 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HMGFFLMG_02113 7.8e-114 ypjP S YpjP-like protein
HMGFFLMG_02114 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HMGFFLMG_02115 1.7e-75 yphP S Belongs to the UPF0403 family
HMGFFLMG_02116 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HMGFFLMG_02117 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
HMGFFLMG_02118 3.1e-110 ypgQ S phosphohydrolase
HMGFFLMG_02119 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HMGFFLMG_02120 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HMGFFLMG_02121 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HMGFFLMG_02122 7.9e-31 cspD K Cold-shock protein
HMGFFLMG_02123 3.8e-16 degR
HMGFFLMG_02124 8.1e-31 S Protein of unknown function (DUF2564)
HMGFFLMG_02125 2.6e-27 ypeQ S Zinc-finger
HMGFFLMG_02126 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HMGFFLMG_02127 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HMGFFLMG_02128 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
HMGFFLMG_02130 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HMGFFLMG_02131 2e-07
HMGFFLMG_02132 1e-38 ypbS S Protein of unknown function (DUF2533)
HMGFFLMG_02133 0.0 ypbR S Dynamin family
HMGFFLMG_02134 5.1e-87 ypbQ S protein conserved in bacteria
HMGFFLMG_02135 4.4e-208 bcsA Q Naringenin-chalcone synthase
HMGFFLMG_02136 1.6e-228 pbuX F xanthine
HMGFFLMG_02137 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMGFFLMG_02138 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HMGFFLMG_02139 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HMGFFLMG_02140 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HMGFFLMG_02141 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HMGFFLMG_02142 3.9e-187 ptxS K transcriptional
HMGFFLMG_02143 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HMGFFLMG_02144 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMGFFLMG_02145 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HMGFFLMG_02147 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMGFFLMG_02148 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMGFFLMG_02149 3.3e-92 ypsA S Belongs to the UPF0398 family
HMGFFLMG_02150 1.3e-237 yprB L RNase_H superfamily
HMGFFLMG_02151 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HMGFFLMG_02152 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HMGFFLMG_02153 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HMGFFLMG_02154 1.2e-48 yppG S YppG-like protein
HMGFFLMG_02156 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HMGFFLMG_02159 2.6e-188 yppC S Protein of unknown function (DUF2515)
HMGFFLMG_02160 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMGFFLMG_02161 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HMGFFLMG_02162 4.7e-93 ypoC
HMGFFLMG_02163 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMGFFLMG_02164 5.7e-129 dnaD L DNA replication protein DnaD
HMGFFLMG_02165 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HMGFFLMG_02166 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HMGFFLMG_02167 3.4e-80 ypmB S protein conserved in bacteria
HMGFFLMG_02168 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HMGFFLMG_02169 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMGFFLMG_02170 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HMGFFLMG_02171 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HMGFFLMG_02172 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HMGFFLMG_02173 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMGFFLMG_02174 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMGFFLMG_02175 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HMGFFLMG_02176 6.9e-130 bshB1 S proteins, LmbE homologs
HMGFFLMG_02177 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HMGFFLMG_02178 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMGFFLMG_02179 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HMGFFLMG_02180 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HMGFFLMG_02181 6.1e-143 ypjB S sporulation protein
HMGFFLMG_02182 4.4e-98 ypjA S membrane
HMGFFLMG_02183 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HMGFFLMG_02184 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HMGFFLMG_02185 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HMGFFLMG_02186 8.5e-78 ypiF S Protein of unknown function (DUF2487)
HMGFFLMG_02187 2.8e-99 ypiB S Belongs to the UPF0302 family
HMGFFLMG_02188 4.1e-234 S COG0457 FOG TPR repeat
HMGFFLMG_02189 4.7e-230 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HMGFFLMG_02190 1.8e-201 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HMGFFLMG_02191 2.1e-199 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMGFFLMG_02192 1.6e-135 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HMGFFLMG_02193 3.9e-226 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HMGFFLMG_02194 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HMGFFLMG_02195 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HMGFFLMG_02196 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMGFFLMG_02197 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMGFFLMG_02198 4.6e-64 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HMGFFLMG_02199 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMGFFLMG_02200 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMGFFLMG_02201 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HMGFFLMG_02202 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HMGFFLMG_02203 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMGFFLMG_02204 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HMGFFLMG_02205 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HMGFFLMG_02206 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HMGFFLMG_02207 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HMGFFLMG_02208 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMGFFLMG_02209 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HMGFFLMG_02210 5.4e-138 yphF
HMGFFLMG_02211 1.6e-18 yphE S Protein of unknown function (DUF2768)
HMGFFLMG_02212 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMGFFLMG_02213 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMGFFLMG_02214 1.6e-28 ypzH
HMGFFLMG_02215 2.5e-161 seaA S YIEGIA protein
HMGFFLMG_02216 1.3e-102 yphA
HMGFFLMG_02217 1e-07 S YpzI-like protein
HMGFFLMG_02218 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMGFFLMG_02219 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HMGFFLMG_02220 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMGFFLMG_02221 1.8e-23 S Family of unknown function (DUF5359)
HMGFFLMG_02222 9.2e-113 ypfA M Flagellar protein YcgR
HMGFFLMG_02223 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HMGFFLMG_02224 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HMGFFLMG_02225 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HMGFFLMG_02226 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HMGFFLMG_02227 7.3e-247 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HMGFFLMG_02228 1.3e-102 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HMGFFLMG_02229 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HMGFFLMG_02230 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HMGFFLMG_02231 4.6e-81 ypbE M Lysin motif
HMGFFLMG_02232 2.2e-100 ypbD S metal-dependent membrane protease
HMGFFLMG_02233 3.2e-286 recQ 3.6.4.12 L DNA helicase
HMGFFLMG_02234 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
HMGFFLMG_02235 4.7e-41 fer C Ferredoxin
HMGFFLMG_02236 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMGFFLMG_02237 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMGFFLMG_02238 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HMGFFLMG_02239 6.8e-201 rsiX
HMGFFLMG_02240 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_02241 0.0 resE 2.7.13.3 T Histidine kinase
HMGFFLMG_02242 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_02243 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HMGFFLMG_02244 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HMGFFLMG_02245 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HMGFFLMG_02246 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMGFFLMG_02247 1.9e-87 spmB S Spore maturation protein
HMGFFLMG_02248 3.5e-103 spmA S Spore maturation protein
HMGFFLMG_02249 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HMGFFLMG_02250 4e-98 ypuI S Protein of unknown function (DUF3907)
HMGFFLMG_02251 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMGFFLMG_02252 4.3e-127 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMGFFLMG_02253 4.5e-94 ypuF S Domain of unknown function (DUF309)
HMGFFLMG_02254 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMGFFLMG_02255 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMGFFLMG_02256 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HMGFFLMG_02257 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
HMGFFLMG_02258 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMGFFLMG_02259 6e-55 ypuD
HMGFFLMG_02260 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HMGFFLMG_02261 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HMGFFLMG_02262 1.5e-17 S SNARE associated Golgi protein
HMGFFLMG_02265 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMGFFLMG_02266 1.3e-149 ypuA S Secreted protein
HMGFFLMG_02267 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMGFFLMG_02268 1.4e-273 spoVAF EG Stage V sporulation protein AF
HMGFFLMG_02269 1.4e-110 spoVAEA S stage V sporulation protein
HMGFFLMG_02270 2.2e-57 spoVAEB S stage V sporulation protein
HMGFFLMG_02271 9e-192 spoVAD I Stage V sporulation protein AD
HMGFFLMG_02272 2.3e-78 spoVAC S stage V sporulation protein AC
HMGFFLMG_02273 1e-67 spoVAB S Stage V sporulation protein AB
HMGFFLMG_02274 7.4e-112 spoVAA S Stage V sporulation protein AA
HMGFFLMG_02275 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMGFFLMG_02276 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HMGFFLMG_02277 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HMGFFLMG_02278 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HMGFFLMG_02279 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HMGFFLMG_02280 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMGFFLMG_02281 2.6e-166 xerD L recombinase XerD
HMGFFLMG_02282 3.7e-37 S Protein of unknown function (DUF4227)
HMGFFLMG_02283 2.4e-80 fur P Belongs to the Fur family
HMGFFLMG_02284 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HMGFFLMG_02285 2e-32 yqkK
HMGFFLMG_02286 5.5e-242 mleA 1.1.1.38 C malic enzyme
HMGFFLMG_02287 3.1e-235 mleN C Na H antiporter
HMGFFLMG_02288 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HMGFFLMG_02289 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HMGFFLMG_02290 4.5e-58 ansR K Transcriptional regulator
HMGFFLMG_02291 3e-223 yqxK 3.6.4.12 L DNA helicase
HMGFFLMG_02292 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HMGFFLMG_02294 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HMGFFLMG_02295 4e-14 yqkE S Protein of unknown function (DUF3886)
HMGFFLMG_02296 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HMGFFLMG_02297 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HMGFFLMG_02298 2.8e-54 yqkB S Belongs to the HesB IscA family
HMGFFLMG_02299 4.7e-196 yqkA K GrpB protein
HMGFFLMG_02300 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HMGFFLMG_02301 3.6e-87 yqjY K acetyltransferase
HMGFFLMG_02302 2.2e-49 S YolD-like protein
HMGFFLMG_02303 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMGFFLMG_02305 5.2e-226 yqjV G Major Facilitator Superfamily
HMGFFLMG_02307 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMGFFLMG_02308 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HMGFFLMG_02309 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HMGFFLMG_02310 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_02311 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HMGFFLMG_02312 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMGFFLMG_02313 0.0 rocB E arginine degradation protein
HMGFFLMG_02314 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HMGFFLMG_02315 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HMGFFLMG_02316 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMGFFLMG_02317 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMGFFLMG_02318 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMGFFLMG_02319 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMGFFLMG_02320 4.5e-24 yqzJ
HMGFFLMG_02321 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMGFFLMG_02322 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
HMGFFLMG_02323 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HMGFFLMG_02324 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HMGFFLMG_02325 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HMGFFLMG_02327 1.4e-98 yqjB S protein conserved in bacteria
HMGFFLMG_02328 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
HMGFFLMG_02329 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HMGFFLMG_02330 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HMGFFLMG_02331 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HMGFFLMG_02332 9.3e-77 yqiW S Belongs to the UPF0403 family
HMGFFLMG_02333 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HMGFFLMG_02334 7.9e-208 norA EGP Major facilitator Superfamily
HMGFFLMG_02335 2.6e-152 bmrR K helix_turn_helix, mercury resistance
HMGFFLMG_02336 5.9e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMGFFLMG_02337 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HMGFFLMG_02338 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HMGFFLMG_02339 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HMGFFLMG_02340 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HMGFFLMG_02341 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HMGFFLMG_02342 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HMGFFLMG_02343 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HMGFFLMG_02344 4e-34 yqzF S Protein of unknown function (DUF2627)
HMGFFLMG_02345 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HMGFFLMG_02346 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HMGFFLMG_02347 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HMGFFLMG_02348 1.8e-212 mmgC I acyl-CoA dehydrogenase
HMGFFLMG_02349 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
HMGFFLMG_02350 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
HMGFFLMG_02351 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMGFFLMG_02352 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HMGFFLMG_02353 5.9e-27
HMGFFLMG_02354 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HMGFFLMG_02356 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HMGFFLMG_02357 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HMGFFLMG_02358 0.0 recN L May be involved in recombinational repair of damaged DNA
HMGFFLMG_02359 1.7e-78 argR K Regulates arginine biosynthesis genes
HMGFFLMG_02360 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HMGFFLMG_02361 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMGFFLMG_02362 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMGFFLMG_02363 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMGFFLMG_02364 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMGFFLMG_02365 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMGFFLMG_02366 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMGFFLMG_02367 2.1e-67 yqhY S protein conserved in bacteria
HMGFFLMG_02368 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HMGFFLMG_02369 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMGFFLMG_02370 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HMGFFLMG_02371 6.9e-103 spoIIIAG S stage III sporulation protein AG
HMGFFLMG_02372 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HMGFFLMG_02373 1.3e-197 spoIIIAE S stage III sporulation protein AE
HMGFFLMG_02374 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HMGFFLMG_02375 7.6e-29 spoIIIAC S stage III sporulation protein AC
HMGFFLMG_02376 2.9e-85 spoIIIAB S Stage III sporulation protein
HMGFFLMG_02377 4.7e-171 spoIIIAA S stage III sporulation protein AA
HMGFFLMG_02378 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HMGFFLMG_02379 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMGFFLMG_02380 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HMGFFLMG_02381 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HMGFFLMG_02382 2.3e-93 yqhR S Conserved membrane protein YqhR
HMGFFLMG_02383 1.5e-172 yqhQ S Protein of unknown function (DUF1385)
HMGFFLMG_02384 2.2e-61 yqhP
HMGFFLMG_02385 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
HMGFFLMG_02386 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HMGFFLMG_02387 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HMGFFLMG_02388 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HMGFFLMG_02389 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HMGFFLMG_02390 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HMGFFLMG_02391 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HMGFFLMG_02392 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HMGFFLMG_02393 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HMGFFLMG_02394 1.2e-24 sinI S Anti-repressor SinI
HMGFFLMG_02395 1e-54 sinR K transcriptional
HMGFFLMG_02396 2.3e-142 tasA S Cell division protein FtsN
HMGFFLMG_02397 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HMGFFLMG_02398 2e-70 yqxM
HMGFFLMG_02399 2.7e-35 yqxM
HMGFFLMG_02400 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HMGFFLMG_02401 1.4e-26 yqzE S YqzE-like protein
HMGFFLMG_02402 3.7e-42 S ComG operon protein 7
HMGFFLMG_02403 5.5e-49 comGF U Putative Competence protein ComGF
HMGFFLMG_02404 1.1e-59 comGE
HMGFFLMG_02405 4.4e-71 gspH NU protein transport across the cell outer membrane
HMGFFLMG_02406 1.4e-47 comGC U Required for transformation and DNA binding
HMGFFLMG_02407 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
HMGFFLMG_02408 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HMGFFLMG_02410 7.2e-175 corA P Mg2 transporter protein
HMGFFLMG_02411 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HMGFFLMG_02412 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HMGFFLMG_02414 7.8e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HMGFFLMG_02415 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HMGFFLMG_02416 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HMGFFLMG_02417 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HMGFFLMG_02418 6.9e-50 yqgV S Thiamine-binding protein
HMGFFLMG_02419 2.7e-199 yqgU
HMGFFLMG_02420 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HMGFFLMG_02421 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMGFFLMG_02422 5.2e-181 glcK 2.7.1.2 G Glucokinase
HMGFFLMG_02423 3.1e-33 yqgQ S Protein conserved in bacteria
HMGFFLMG_02424 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HMGFFLMG_02425 2.5e-09 yqgO
HMGFFLMG_02426 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMGFFLMG_02427 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMGFFLMG_02428 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HMGFFLMG_02430 9.2e-51 yqzD
HMGFFLMG_02431 1.9e-75 yqzC S YceG-like family
HMGFFLMG_02432 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMGFFLMG_02433 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMGFFLMG_02434 4.4e-158 pstA P Phosphate transport system permease
HMGFFLMG_02435 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
HMGFFLMG_02436 5.3e-151 pstS P Phosphate
HMGFFLMG_02437 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HMGFFLMG_02438 2.5e-231 yqgE EGP Major facilitator superfamily
HMGFFLMG_02439 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HMGFFLMG_02440 4e-73 yqgC S protein conserved in bacteria
HMGFFLMG_02441 8.5e-134 yqgB S Protein of unknown function (DUF1189)
HMGFFLMG_02442 2.2e-75 yqgA
HMGFFLMG_02443 5.2e-47 yqfZ M LysM domain
HMGFFLMG_02444 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HMGFFLMG_02445 4.3e-62 yqfX S membrane
HMGFFLMG_02446 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HMGFFLMG_02447 1.9e-77 zur P Belongs to the Fur family
HMGFFLMG_02448 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HMGFFLMG_02449 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HMGFFLMG_02450 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HMGFFLMG_02451 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMGFFLMG_02452 2.9e-14 yqfQ S YqfQ-like protein
HMGFFLMG_02453 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HMGFFLMG_02454 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMGFFLMG_02455 3.5e-112 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMGFFLMG_02456 2.2e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
HMGFFLMG_02457 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMGFFLMG_02458 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMGFFLMG_02459 4.5e-88 yaiI S Belongs to the UPF0178 family
HMGFFLMG_02460 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMGFFLMG_02461 4.5e-112 ccpN K CBS domain
HMGFFLMG_02462 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMGFFLMG_02463 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMGFFLMG_02464 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
HMGFFLMG_02465 8.4e-19 S YqzL-like protein
HMGFFLMG_02466 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMGFFLMG_02467 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HMGFFLMG_02468 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HMGFFLMG_02469 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMGFFLMG_02470 0.0 yqfF S membrane-associated HD superfamily hydrolase
HMGFFLMG_02472 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
HMGFFLMG_02473 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HMGFFLMG_02474 2.7e-45 yqfC S sporulation protein YqfC
HMGFFLMG_02475 6e-25 yqfB
HMGFFLMG_02476 4.3e-122 yqfA S UPF0365 protein
HMGFFLMG_02477 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HMGFFLMG_02478 2.5e-61 yqeY S Yqey-like protein
HMGFFLMG_02479 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMGFFLMG_02480 1.6e-158 yqeW P COG1283 Na phosphate symporter
HMGFFLMG_02481 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HMGFFLMG_02482 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMGFFLMG_02483 5.4e-175 prmA J Methylates ribosomal protein L11
HMGFFLMG_02484 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMGFFLMG_02485 0.0 dnaK O Heat shock 70 kDa protein
HMGFFLMG_02486 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMGFFLMG_02487 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMGFFLMG_02488 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
HMGFFLMG_02489 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMGFFLMG_02490 1e-54 yqxA S Protein of unknown function (DUF3679)
HMGFFLMG_02491 6.9e-223 spoIIP M stage II sporulation protein P
HMGFFLMG_02492 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HMGFFLMG_02493 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HMGFFLMG_02494 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HMGFFLMG_02495 4.1e-15 S YqzM-like protein
HMGFFLMG_02496 0.0 comEC S Competence protein ComEC
HMGFFLMG_02497 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HMGFFLMG_02498 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HMGFFLMG_02499 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMGFFLMG_02500 2.9e-139 yqeM Q Methyltransferase
HMGFFLMG_02501 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMGFFLMG_02502 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HMGFFLMG_02503 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMGFFLMG_02504 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HMGFFLMG_02505 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMGFFLMG_02506 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HMGFFLMG_02507 5.3e-95 yqeG S hydrolase of the HAD superfamily
HMGFFLMG_02509 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HMGFFLMG_02510 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMGFFLMG_02511 4.7e-106 yqeD S SNARE associated Golgi protein
HMGFFLMG_02512 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HMGFFLMG_02513 2.3e-133 yqeB
HMGFFLMG_02514 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HMGFFLMG_02515 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMGFFLMG_02516 1.4e-281 cisA2 L Recombinase
HMGFFLMG_02517 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HMGFFLMG_02518 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
HMGFFLMG_02519 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMGFFLMG_02520 1.6e-54 arsR K ArsR family transcriptional regulator
HMGFFLMG_02521 1.1e-152 yqcI S YqcI/YcgG family
HMGFFLMG_02522 1.6e-96 S Tetratricopeptide repeat
HMGFFLMG_02525 3.8e-277 A Pre-toxin TG
HMGFFLMG_02526 1.1e-104 S Suppressor of fused protein (SUFU)
HMGFFLMG_02528 5e-60
HMGFFLMG_02530 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HMGFFLMG_02531 2.6e-68 S Bacteriophage holin family
HMGFFLMG_02532 4.8e-165 xepA
HMGFFLMG_02533 1.3e-23
HMGFFLMG_02534 4.1e-56 xkdW S XkdW protein
HMGFFLMG_02535 2e-221
HMGFFLMG_02536 9.6e-40
HMGFFLMG_02537 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HMGFFLMG_02538 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HMGFFLMG_02539 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HMGFFLMG_02540 1.8e-38 xkdR S Protein of unknown function (DUF2577)
HMGFFLMG_02541 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
HMGFFLMG_02542 9e-114 xkdP S Lysin motif
HMGFFLMG_02543 0.0 xkdO L Transglycosylase SLT domain
HMGFFLMG_02544 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
HMGFFLMG_02546 3.6e-76 xkdM S Phage tail tube protein
HMGFFLMG_02547 5.5e-256 xkdK S Phage tail sheath C-terminal domain
HMGFFLMG_02548 3.2e-26
HMGFFLMG_02549 1.4e-77
HMGFFLMG_02550 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
HMGFFLMG_02551 6.7e-65 yqbH S Domain of unknown function (DUF3599)
HMGFFLMG_02552 2.1e-67 S Protein of unknown function (DUF3199)
HMGFFLMG_02553 3.6e-51 S YqbF, hypothetical protein domain
HMGFFLMG_02554 1.9e-167 xkdG S Phage capsid family
HMGFFLMG_02555 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HMGFFLMG_02556 2e-115
HMGFFLMG_02557 5.7e-169 S Phage Mu protein F like protein
HMGFFLMG_02558 5.9e-296 yqbA S portal protein
HMGFFLMG_02559 2.4e-253 S phage terminase, large subunit
HMGFFLMG_02560 6.3e-107 yqaS L DNA packaging
HMGFFLMG_02562 6.5e-81 L Transposase
HMGFFLMG_02563 1.6e-166
HMGFFLMG_02564 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
HMGFFLMG_02565 7.2e-74 rusA L Endodeoxyribonuclease RusA
HMGFFLMG_02567 5.9e-168 xkdC L IstB-like ATP binding protein
HMGFFLMG_02568 4.7e-123 3.1.3.16 L DnaD domain protein
HMGFFLMG_02569 2.5e-155 recT L RecT family
HMGFFLMG_02570 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
HMGFFLMG_02574 1.2e-103
HMGFFLMG_02576 6.5e-37 K Helix-turn-helix XRE-family like proteins
HMGFFLMG_02577 1.1e-56 K sequence-specific DNA binding
HMGFFLMG_02579 1e-101 adk 2.7.4.3 F adenylate kinase activity
HMGFFLMG_02580 1.4e-100 yqaB E IrrE N-terminal-like domain
HMGFFLMG_02581 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HMGFFLMG_02582 2e-68 psiE S Protein PsiE homolog
HMGFFLMG_02583 9e-237 yrkQ T Histidine kinase
HMGFFLMG_02584 1.1e-127 T Transcriptional regulator
HMGFFLMG_02585 8.2e-224 yrkO P Protein of unknown function (DUF418)
HMGFFLMG_02586 6e-105 yrkN K Acetyltransferase (GNAT) family
HMGFFLMG_02587 1.5e-97 ywrO S Flavodoxin-like fold
HMGFFLMG_02588 2.8e-79 S Protein of unknown function with HXXEE motif
HMGFFLMG_02589 4.3e-117 yrkJ S membrane transporter protein
HMGFFLMG_02590 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HMGFFLMG_02591 1.1e-219 yrkH P Rhodanese Homology Domain
HMGFFLMG_02592 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
HMGFFLMG_02593 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
HMGFFLMG_02594 7.8e-39 yrkD S protein conserved in bacteria
HMGFFLMG_02595 2.6e-108 yrkC G Cupin domain
HMGFFLMG_02596 4.8e-151 bltR K helix_turn_helix, mercury resistance
HMGFFLMG_02597 3.5e-211 blt EGP Major facilitator Superfamily
HMGFFLMG_02598 1.4e-83 bltD 2.3.1.57 K FR47-like protein
HMGFFLMG_02599 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HMGFFLMG_02600 2.1e-17 S YrzO-like protein
HMGFFLMG_02601 1.7e-171 yrdR EG EamA-like transporter family
HMGFFLMG_02602 5.9e-160 yrdQ K Transcriptional regulator
HMGFFLMG_02603 2e-199 trkA P Oxidoreductase
HMGFFLMG_02604 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
HMGFFLMG_02605 1.3e-66 yodA S tautomerase
HMGFFLMG_02606 7.7e-163 gltR K LysR substrate binding domain
HMGFFLMG_02608 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
HMGFFLMG_02609 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HMGFFLMG_02610 3.3e-138 azlC E AzlC protein
HMGFFLMG_02611 2.2e-79 bkdR K helix_turn_helix ASNC type
HMGFFLMG_02612 4.1e-46 yrdF K ribonuclease inhibitor
HMGFFLMG_02613 4.1e-231 cypA C Cytochrome P450
HMGFFLMG_02615 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
HMGFFLMG_02616 1.9e-57 S Protein of unknown function (DUF2568)
HMGFFLMG_02617 1.2e-91 yrdA S DinB family
HMGFFLMG_02618 7.6e-168 aadK G Streptomycin adenylyltransferase
HMGFFLMG_02619 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HMGFFLMG_02620 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMGFFLMG_02621 3e-125 yrpD S Domain of unknown function, YrpD
HMGFFLMG_02623 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HMGFFLMG_02624 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_02625 4.5e-188 yrpG C Aldo/keto reductase family
HMGFFLMG_02626 9.5e-226 yraO C Citrate transporter
HMGFFLMG_02627 1.2e-163 yraN K Transcriptional regulator
HMGFFLMG_02628 2.4e-206 yraM S PrpF protein
HMGFFLMG_02630 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HMGFFLMG_02631 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMGFFLMG_02632 3.2e-155 S Alpha beta hydrolase
HMGFFLMG_02633 1.7e-60 T sh3 domain protein
HMGFFLMG_02634 2.4e-61 T sh3 domain protein
HMGFFLMG_02635 1.3e-66 E Glyoxalase-like domain
HMGFFLMG_02636 5.3e-37 yraG
HMGFFLMG_02637 6.4e-63 yraF M Spore coat protein
HMGFFLMG_02638 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HMGFFLMG_02639 2.6e-26 yraE
HMGFFLMG_02640 1.1e-49 yraD M Spore coat protein
HMGFFLMG_02641 4.3e-47 yraB K helix_turn_helix, mercury resistance
HMGFFLMG_02642 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
HMGFFLMG_02643 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
HMGFFLMG_02644 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HMGFFLMG_02645 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HMGFFLMG_02646 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HMGFFLMG_02647 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HMGFFLMG_02648 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HMGFFLMG_02649 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
HMGFFLMG_02650 0.0 levR K PTS system fructose IIA component
HMGFFLMG_02651 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HMGFFLMG_02652 3.6e-106 yrhP E LysE type translocator
HMGFFLMG_02653 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
HMGFFLMG_02654 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_02655 1.7e-151 rsiV S Protein of unknown function (DUF3298)
HMGFFLMG_02656 0.0 yrhL I Acyltransferase family
HMGFFLMG_02657 1.5e-46 yrhK S YrhK-like protein
HMGFFLMG_02658 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HMGFFLMG_02659 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HMGFFLMG_02660 4.5e-97 yrhH Q methyltransferase
HMGFFLMG_02663 1.8e-142 focA P Formate nitrite
HMGFFLMG_02664 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HMGFFLMG_02665 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HMGFFLMG_02666 1.4e-78 yrhD S Protein of unknown function (DUF1641)
HMGFFLMG_02667 4.6e-35 yrhC S YrhC-like protein
HMGFFLMG_02668 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMGFFLMG_02669 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HMGFFLMG_02670 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMGFFLMG_02671 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HMGFFLMG_02672 7e-27 yrzA S Protein of unknown function (DUF2536)
HMGFFLMG_02673 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HMGFFLMG_02674 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HMGFFLMG_02675 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMGFFLMG_02676 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HMGFFLMG_02677 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HMGFFLMG_02678 7.8e-174 yegQ O Peptidase U32
HMGFFLMG_02679 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
HMGFFLMG_02680 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMGFFLMG_02681 1.2e-45 yrzB S Belongs to the UPF0473 family
HMGFFLMG_02682 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMGFFLMG_02683 1.7e-41 yrzL S Belongs to the UPF0297 family
HMGFFLMG_02684 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMGFFLMG_02685 2.7e-170 yrrI S AI-2E family transporter
HMGFFLMG_02686 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HMGFFLMG_02687 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
HMGFFLMG_02688 3.6e-109 gluC P ABC transporter
HMGFFLMG_02689 7.6e-107 glnP P ABC transporter
HMGFFLMG_02690 8e-08 S Protein of unknown function (DUF3918)
HMGFFLMG_02691 9.8e-31 yrzR
HMGFFLMG_02692 1.8e-83 yrrD S protein conserved in bacteria
HMGFFLMG_02693 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMGFFLMG_02694 1.4e-15 S COG0457 FOG TPR repeat
HMGFFLMG_02695 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMGFFLMG_02696 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
HMGFFLMG_02697 1.2e-70 cymR K Transcriptional regulator
HMGFFLMG_02698 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HMGFFLMG_02699 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HMGFFLMG_02700 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HMGFFLMG_02701 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMGFFLMG_02703 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
HMGFFLMG_02704 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMGFFLMG_02705 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMGFFLMG_02706 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMGFFLMG_02707 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMGFFLMG_02708 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HMGFFLMG_02709 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HMGFFLMG_02710 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HMGFFLMG_02711 9.4e-49 yrzD S Post-transcriptional regulator
HMGFFLMG_02712 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMGFFLMG_02713 2.2e-114 yrbG S membrane
HMGFFLMG_02714 1.2e-74 yrzE S Protein of unknown function (DUF3792)
HMGFFLMG_02715 1.1e-38 yajC U Preprotein translocase subunit YajC
HMGFFLMG_02716 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMGFFLMG_02717 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMGFFLMG_02718 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HMGFFLMG_02719 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMGFFLMG_02720 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMGFFLMG_02721 4.8e-93 bofC S BofC C-terminal domain
HMGFFLMG_02722 5.3e-253 csbX EGP Major facilitator Superfamily
HMGFFLMG_02723 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HMGFFLMG_02724 6.5e-119 yrzF T serine threonine protein kinase
HMGFFLMG_02726 2.6e-35 S Family of unknown function (DUF5412)
HMGFFLMG_02727 1.8e-262 alsT E Sodium alanine symporter
HMGFFLMG_02728 1.9e-127 yebC K transcriptional regulatory protein
HMGFFLMG_02729 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMGFFLMG_02730 9.8e-158 safA M spore coat assembly protein SafA
HMGFFLMG_02731 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HMGFFLMG_02732 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HMGFFLMG_02733 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HMGFFLMG_02734 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
HMGFFLMG_02735 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HMGFFLMG_02736 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
HMGFFLMG_02737 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HMGFFLMG_02738 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMGFFLMG_02739 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HMGFFLMG_02740 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMGFFLMG_02741 4.1e-56 ysxB J ribosomal protein
HMGFFLMG_02742 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMGFFLMG_02743 9.2e-161 spoIVFB S Stage IV sporulation protein
HMGFFLMG_02744 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HMGFFLMG_02745 2.5e-144 minD D Belongs to the ParA family
HMGFFLMG_02746 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HMGFFLMG_02747 1.4e-84 mreD M shape-determining protein
HMGFFLMG_02748 2.8e-157 mreC M Involved in formation and maintenance of cell shape
HMGFFLMG_02749 1.8e-184 mreB D Rod shape-determining protein MreB
HMGFFLMG_02750 5.9e-126 radC E Belongs to the UPF0758 family
HMGFFLMG_02751 2.8e-102 maf D septum formation protein Maf
HMGFFLMG_02752 1.1e-168 spoIIB S Sporulation related domain
HMGFFLMG_02753 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HMGFFLMG_02754 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMGFFLMG_02755 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMGFFLMG_02756 1.6e-25
HMGFFLMG_02757 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HMGFFLMG_02758 1.9e-226 spoVID M stage VI sporulation protein D
HMGFFLMG_02759 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HMGFFLMG_02760 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
HMGFFLMG_02761 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HMGFFLMG_02762 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HMGFFLMG_02763 3.6e-146 hemX O cytochrome C
HMGFFLMG_02764 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HMGFFLMG_02765 1.4e-89 ysxD
HMGFFLMG_02766 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HMGFFLMG_02767 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HMGFFLMG_02768 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HMGFFLMG_02769 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMGFFLMG_02770 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMGFFLMG_02771 2.3e-187 ysoA H Tetratricopeptide repeat
HMGFFLMG_02772 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMGFFLMG_02773 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMGFFLMG_02774 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HMGFFLMG_02775 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMGFFLMG_02776 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMGFFLMG_02777 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HMGFFLMG_02778 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HMGFFLMG_02780 7.6e-82 ysnE K acetyltransferase
HMGFFLMG_02781 9.1e-134 ysnF S protein conserved in bacteria
HMGFFLMG_02783 1.4e-92 ysnB S Phosphoesterase
HMGFFLMG_02784 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMGFFLMG_02785 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HMGFFLMG_02786 2.9e-196 gerM S COG5401 Spore germination protein
HMGFFLMG_02787 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMGFFLMG_02788 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HMGFFLMG_02789 3.3e-30 gerE K Transcriptional regulator
HMGFFLMG_02790 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HMGFFLMG_02791 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HMGFFLMG_02792 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HMGFFLMG_02793 2.4e-107 sdhC C succinate dehydrogenase
HMGFFLMG_02794 1.2e-79 yslB S Protein of unknown function (DUF2507)
HMGFFLMG_02795 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HMGFFLMG_02796 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMGFFLMG_02797 2e-52 trxA O Belongs to the thioredoxin family
HMGFFLMG_02798 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HMGFFLMG_02800 4.2e-178 etfA C Electron transfer flavoprotein
HMGFFLMG_02801 1.2e-135 etfB C Electron transfer flavoprotein
HMGFFLMG_02802 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HMGFFLMG_02803 2.7e-100 fadR K Transcriptional regulator
HMGFFLMG_02804 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HMGFFLMG_02805 7.3e-68 yshE S membrane
HMGFFLMG_02806 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMGFFLMG_02807 0.0 polX L COG1796 DNA polymerase IV (family X)
HMGFFLMG_02808 1.3e-85 cvpA S membrane protein, required for colicin V production
HMGFFLMG_02809 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HMGFFLMG_02810 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMGFFLMG_02811 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMGFFLMG_02812 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMGFFLMG_02813 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMGFFLMG_02814 2.6e-32 sspI S Belongs to the SspI family
HMGFFLMG_02815 4.4e-208 ysfB KT regulator
HMGFFLMG_02816 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
HMGFFLMG_02817 5.6e-258 glcF C Glycolate oxidase
HMGFFLMG_02818 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
HMGFFLMG_02820 0.0 cstA T Carbon starvation protein
HMGFFLMG_02821 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HMGFFLMG_02822 3.4e-144 araQ G transport system permease
HMGFFLMG_02823 1.4e-167 araP G carbohydrate transport
HMGFFLMG_02824 2.8e-254 araN G carbohydrate transport
HMGFFLMG_02825 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HMGFFLMG_02826 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HMGFFLMG_02827 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HMGFFLMG_02828 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HMGFFLMG_02829 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HMGFFLMG_02830 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HMGFFLMG_02831 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HMGFFLMG_02832 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HMGFFLMG_02833 7.5e-45 ysdA S Membrane
HMGFFLMG_02834 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMGFFLMG_02835 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMGFFLMG_02836 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMGFFLMG_02838 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HMGFFLMG_02839 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HMGFFLMG_02840 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
HMGFFLMG_02841 0.0 lytS 2.7.13.3 T Histidine kinase
HMGFFLMG_02842 1.5e-149 ysaA S HAD-hyrolase-like
HMGFFLMG_02843 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMGFFLMG_02844 3.8e-159 ytxC S YtxC-like family
HMGFFLMG_02845 4.9e-111 ytxB S SNARE associated Golgi protein
HMGFFLMG_02846 3e-173 dnaI L Primosomal protein DnaI
HMGFFLMG_02847 3.5e-266 dnaB L Membrane attachment protein
HMGFFLMG_02848 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMGFFLMG_02849 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HMGFFLMG_02850 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMGFFLMG_02851 9.9e-67 ytcD K Transcriptional regulator
HMGFFLMG_02852 4.9e-205 ytbD EGP Major facilitator Superfamily
HMGFFLMG_02853 8.9e-161 ytbE S reductase
HMGFFLMG_02854 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMGFFLMG_02855 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HMGFFLMG_02856 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMGFFLMG_02857 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMGFFLMG_02858 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HMGFFLMG_02859 8.3e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_02860 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HMGFFLMG_02861 1.8e-242 icd 1.1.1.42 C isocitrate
HMGFFLMG_02862 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HMGFFLMG_02863 4.7e-71 yeaL S membrane
HMGFFLMG_02864 2.6e-192 ytvI S sporulation integral membrane protein YtvI
HMGFFLMG_02865 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HMGFFLMG_02866 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMGFFLMG_02867 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMGFFLMG_02868 1.6e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HMGFFLMG_02869 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMGFFLMG_02870 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HMGFFLMG_02871 0.0 dnaE 2.7.7.7 L DNA polymerase
HMGFFLMG_02872 3.2e-56 ytrH S Sporulation protein YtrH
HMGFFLMG_02873 8.2e-69 ytrI
HMGFFLMG_02874 9.2e-29
HMGFFLMG_02875 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HMGFFLMG_02876 2.4e-47 ytpI S YtpI-like protein
HMGFFLMG_02877 8e-241 ytoI K transcriptional regulator containing CBS domains
HMGFFLMG_02878 1.2e-158 ytnM S membrane transporter protein
HMGFFLMG_02879 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
HMGFFLMG_02880 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HMGFFLMG_02881 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMGFFLMG_02882 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
HMGFFLMG_02883 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMGFFLMG_02884 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HMGFFLMG_02885 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
HMGFFLMG_02886 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
HMGFFLMG_02887 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
HMGFFLMG_02888 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
HMGFFLMG_02889 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
HMGFFLMG_02890 2.9e-173 ytlI K LysR substrate binding domain
HMGFFLMG_02891 1.7e-130 ytkL S Belongs to the UPF0173 family
HMGFFLMG_02892 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMGFFLMG_02894 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
HMGFFLMG_02895 2.2e-102 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMGFFLMG_02896 8.5e-70 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMGFFLMG_02897 5.7e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HMGFFLMG_02898 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMGFFLMG_02899 7e-165 ytxK 2.1.1.72 L DNA methylase
HMGFFLMG_02900 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMGFFLMG_02901 8.7e-70 ytfJ S Sporulation protein YtfJ
HMGFFLMG_02902 5.6e-116 ytfI S Protein of unknown function (DUF2953)
HMGFFLMG_02903 1.3e-87 yteJ S RDD family
HMGFFLMG_02904 2.4e-181 sppA OU signal peptide peptidase SppA
HMGFFLMG_02905 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMGFFLMG_02906 0.0 ytcJ S amidohydrolase
HMGFFLMG_02907 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HMGFFLMG_02908 2e-29 sspB S spore protein
HMGFFLMG_02909 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMGFFLMG_02910 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
HMGFFLMG_02911 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HMGFFLMG_02912 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMGFFLMG_02913 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HMGFFLMG_02914 3.4e-109 yttP K Transcriptional regulator
HMGFFLMG_02915 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HMGFFLMG_02916 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HMGFFLMG_02917 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMGFFLMG_02919 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMGFFLMG_02920 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HMGFFLMG_02921 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HMGFFLMG_02922 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HMGFFLMG_02923 1.9e-225 acuC BQ histone deacetylase
HMGFFLMG_02924 1.4e-125 motS N Flagellar motor protein
HMGFFLMG_02925 7.1e-147 motA N flagellar motor
HMGFFLMG_02926 1.7e-182 ccpA K catabolite control protein A
HMGFFLMG_02927 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HMGFFLMG_02928 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
HMGFFLMG_02929 6.6e-17 ytxH S COG4980 Gas vesicle protein
HMGFFLMG_02930 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMGFFLMG_02931 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMGFFLMG_02932 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HMGFFLMG_02933 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMGFFLMG_02934 9.8e-149 ytpQ S Belongs to the UPF0354 family
HMGFFLMG_02935 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMGFFLMG_02936 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HMGFFLMG_02937 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HMGFFLMG_02938 9.8e-52 ytzB S small secreted protein
HMGFFLMG_02939 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HMGFFLMG_02940 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HMGFFLMG_02941 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMGFFLMG_02942 2e-45 ytzH S YtzH-like protein
HMGFFLMG_02943 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HMGFFLMG_02944 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HMGFFLMG_02945 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HMGFFLMG_02946 1.3e-165 ytlQ
HMGFFLMG_02947 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HMGFFLMG_02948 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMGFFLMG_02949 7.1e-272 pepV 3.5.1.18 E Dipeptidase
HMGFFLMG_02950 7.2e-226 pbuO S permease
HMGFFLMG_02951 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
HMGFFLMG_02952 4.3e-132 ythP V ABC transporter
HMGFFLMG_02953 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HMGFFLMG_02954 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMGFFLMG_02955 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMGFFLMG_02956 8.2e-232 ytfP S HI0933-like protein
HMGFFLMG_02957 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HMGFFLMG_02958 3.1e-26 yteV S Sporulation protein Cse60
HMGFFLMG_02959 4.8e-117 yteU S Integral membrane protein
HMGFFLMG_02960 2.6e-249 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HMGFFLMG_02961 4.6e-73 yteS G transport
HMGFFLMG_02962 8.9e-225 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HMGFFLMG_02963 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HMGFFLMG_02964 0.0 ytdP K Transcriptional regulator
HMGFFLMG_02965 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HMGFFLMG_02966 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HMGFFLMG_02967 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HMGFFLMG_02968 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
HMGFFLMG_02969 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HMGFFLMG_02970 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HMGFFLMG_02971 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HMGFFLMG_02972 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HMGFFLMG_02973 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HMGFFLMG_02974 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
HMGFFLMG_02975 2.3e-190 msmR K Transcriptional regulator
HMGFFLMG_02976 2.3e-248 msmE G Bacterial extracellular solute-binding protein
HMGFFLMG_02977 1.5e-169 amyD P ABC transporter
HMGFFLMG_02978 1.5e-144 amyC P ABC transporter (permease)
HMGFFLMG_02979 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HMGFFLMG_02980 2.1e-51 ytwF P Sulfurtransferase
HMGFFLMG_02981 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMGFFLMG_02982 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HMGFFLMG_02983 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HMGFFLMG_02984 2.1e-211 yttB EGP Major facilitator Superfamily
HMGFFLMG_02985 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HMGFFLMG_02986 0.0 bceB V ABC transporter (permease)
HMGFFLMG_02987 1.1e-138 bceA V ABC transporter, ATP-binding protein
HMGFFLMG_02988 5.6e-186 T PhoQ Sensor
HMGFFLMG_02989 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_02990 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HMGFFLMG_02991 3.1e-127 ytrE V ABC transporter, ATP-binding protein
HMGFFLMG_02992 5.9e-148
HMGFFLMG_02993 6.1e-169 P ABC-2 family transporter protein
HMGFFLMG_02994 1.1e-161 ytrB P abc transporter atp-binding protein
HMGFFLMG_02995 5.1e-66 ytrA K GntR family transcriptional regulator
HMGFFLMG_02997 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HMGFFLMG_02998 2.1e-190 yhcC S Fe-S oxidoreductase
HMGFFLMG_02999 3.3e-106 ytqB J Putative rRNA methylase
HMGFFLMG_03000 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HMGFFLMG_03001 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HMGFFLMG_03002 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HMGFFLMG_03003 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HMGFFLMG_03004 0.0 asnB 6.3.5.4 E Asparagine synthase
HMGFFLMG_03005 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMGFFLMG_03006 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HMGFFLMG_03007 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HMGFFLMG_03008 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HMGFFLMG_03009 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HMGFFLMG_03010 1.4e-144 ytlC P ABC transporter
HMGFFLMG_03011 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HMGFFLMG_03012 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HMGFFLMG_03013 5.4e-63 ytkC S Bacteriophage holin family
HMGFFLMG_03014 2.1e-76 dps P Belongs to the Dps family
HMGFFLMG_03016 3.6e-73 ytkA S YtkA-like
HMGFFLMG_03017 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMGFFLMG_03018 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HMGFFLMG_03019 3.6e-41 rpmE2 J Ribosomal protein L31
HMGFFLMG_03020 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
HMGFFLMG_03021 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HMGFFLMG_03022 1.1e-24 S Domain of Unknown Function (DUF1540)
HMGFFLMG_03023 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HMGFFLMG_03024 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HMGFFLMG_03025 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HMGFFLMG_03026 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
HMGFFLMG_03027 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HMGFFLMG_03028 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HMGFFLMG_03029 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HMGFFLMG_03030 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HMGFFLMG_03031 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HMGFFLMG_03032 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
HMGFFLMG_03033 2.6e-132 dksA T COG1734 DnaK suppressor protein
HMGFFLMG_03034 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
HMGFFLMG_03035 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMGFFLMG_03036 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HMGFFLMG_03037 3.6e-235 ytcC M Glycosyltransferase Family 4
HMGFFLMG_03039 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
HMGFFLMG_03040 1.8e-217 cotSA M Glycosyl transferases group 1
HMGFFLMG_03041 1.8e-206 cotI S Spore coat protein
HMGFFLMG_03042 9.9e-77 tspO T membrane
HMGFFLMG_03043 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HMGFFLMG_03044 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HMGFFLMG_03045 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HMGFFLMG_03046 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMGFFLMG_03047 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMGFFLMG_03056 7.8e-08
HMGFFLMG_03057 1.3e-09
HMGFFLMG_03064 2e-08
HMGFFLMG_03070 2e-08
HMGFFLMG_03075 3.4e-39 S COG NOG14552 non supervised orthologous group
HMGFFLMG_03076 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HMGFFLMG_03077 3.4e-94 M1-753 M FR47-like protein
HMGFFLMG_03078 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HMGFFLMG_03079 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HMGFFLMG_03080 3.9e-84 yuaE S DinB superfamily
HMGFFLMG_03081 7.9e-108 yuaD
HMGFFLMG_03082 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HMGFFLMG_03083 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HMGFFLMG_03084 1.1e-95 yuaC K Belongs to the GbsR family
HMGFFLMG_03085 2.2e-91 yuaB
HMGFFLMG_03086 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
HMGFFLMG_03087 5.4e-237 ktrB P Potassium
HMGFFLMG_03088 1e-38 yiaA S yiaA/B two helix domain
HMGFFLMG_03089 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMGFFLMG_03090 6.2e-277 yubD P Major Facilitator Superfamily
HMGFFLMG_03091 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HMGFFLMG_03093 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HMGFFLMG_03094 6.3e-197 yubA S transporter activity
HMGFFLMG_03095 3.3e-183 ygjR S Oxidoreductase
HMGFFLMG_03096 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HMGFFLMG_03097 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HMGFFLMG_03098 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HMGFFLMG_03099 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HMGFFLMG_03100 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HMGFFLMG_03101 5.1e-239 mcpA NT chemotaxis protein
HMGFFLMG_03102 2.2e-295 mcpA NT chemotaxis protein
HMGFFLMG_03103 1.5e-222 mcpA NT chemotaxis protein
HMGFFLMG_03104 3.2e-225 mcpA NT chemotaxis protein
HMGFFLMG_03105 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HMGFFLMG_03106 1.5e-34
HMGFFLMG_03107 2.1e-72 yugU S Uncharacterised protein family UPF0047
HMGFFLMG_03108 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HMGFFLMG_03109 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HMGFFLMG_03110 1.4e-116 yugP S Zn-dependent protease
HMGFFLMG_03111 4.6e-39
HMGFFLMG_03112 1.1e-53 mstX S Membrane-integrating protein Mistic
HMGFFLMG_03113 1.7e-182 yugO P COG1226 Kef-type K transport systems
HMGFFLMG_03114 1.3e-72 yugN S YugN-like family
HMGFFLMG_03116 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
HMGFFLMG_03117 2.8e-229 yugK C Dehydrogenase
HMGFFLMG_03118 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HMGFFLMG_03119 1.1e-34 yuzA S Domain of unknown function (DUF378)
HMGFFLMG_03120 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HMGFFLMG_03121 4.3e-200 yugH 2.6.1.1 E Aminotransferase
HMGFFLMG_03122 1.6e-85 alaR K Transcriptional regulator
HMGFFLMG_03123 1e-156 yugF I Hydrolase
HMGFFLMG_03124 9.8e-42 yugE S Domain of unknown function (DUF1871)
HMGFFLMG_03125 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HMGFFLMG_03126 4.6e-233 T PhoQ Sensor
HMGFFLMG_03127 2e-70 kapB G Kinase associated protein B
HMGFFLMG_03128 1.9e-115 kapD L the KinA pathway to sporulation
HMGFFLMG_03130 3.5e-186 yuxJ EGP Major facilitator Superfamily
HMGFFLMG_03131 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HMGFFLMG_03132 6.3e-75 yuxK S protein conserved in bacteria
HMGFFLMG_03133 6.3e-78 yufK S Family of unknown function (DUF5366)
HMGFFLMG_03134 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HMGFFLMG_03135 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HMGFFLMG_03136 2.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HMGFFLMG_03137 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HMGFFLMG_03138 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
HMGFFLMG_03139 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HMGFFLMG_03140 1.3e-233 maeN C COG3493 Na citrate symporter
HMGFFLMG_03141 1.9e-14
HMGFFLMG_03142 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HMGFFLMG_03143 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMGFFLMG_03144 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMGFFLMG_03145 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMGFFLMG_03146 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMGFFLMG_03147 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HMGFFLMG_03148 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HMGFFLMG_03149 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
HMGFFLMG_03150 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMGFFLMG_03151 0.0 comP 2.7.13.3 T Histidine kinase
HMGFFLMG_03153 2.5e-162 comQ H Polyprenyl synthetase
HMGFFLMG_03155 1.1e-22 yuzC
HMGFFLMG_03156 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HMGFFLMG_03157 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMGFFLMG_03158 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
HMGFFLMG_03159 1.6e-67 yueI S Protein of unknown function (DUF1694)
HMGFFLMG_03160 7.4e-39 yueH S YueH-like protein
HMGFFLMG_03161 2.1e-32 yueG S Spore germination protein gerPA/gerPF
HMGFFLMG_03162 1.9e-190 yueF S transporter activity
HMGFFLMG_03163 6.1e-72 S Protein of unknown function (DUF2283)
HMGFFLMG_03164 2.9e-24 S Protein of unknown function (DUF2642)
HMGFFLMG_03165 4.8e-96 yueE S phosphohydrolase
HMGFFLMG_03166 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMGFFLMG_03167 6.6e-65 yueC S Family of unknown function (DUF5383)
HMGFFLMG_03168 0.0 esaA S type VII secretion protein EsaA
HMGFFLMG_03169 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HMGFFLMG_03170 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HMGFFLMG_03171 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HMGFFLMG_03172 2.8e-45 esxA S Belongs to the WXG100 family
HMGFFLMG_03173 1.5e-228 yukF QT Transcriptional regulator
HMGFFLMG_03174 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HMGFFLMG_03175 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HMGFFLMG_03176 3.8e-36 mbtH S MbtH-like protein
HMGFFLMG_03177 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMGFFLMG_03178 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HMGFFLMG_03179 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HMGFFLMG_03180 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
HMGFFLMG_03181 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_03182 1.3e-167 besA S Putative esterase
HMGFFLMG_03183 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HMGFFLMG_03184 1.1e-93 bioY S Biotin biosynthesis protein
HMGFFLMG_03185 3.9e-211 yuiF S antiporter
HMGFFLMG_03186 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HMGFFLMG_03187 1.2e-77 yuiD S protein conserved in bacteria
HMGFFLMG_03188 9.5e-118 yuiC S protein conserved in bacteria
HMGFFLMG_03189 8.4e-27 yuiB S Putative membrane protein
HMGFFLMG_03190 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HMGFFLMG_03191 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HMGFFLMG_03193 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMGFFLMG_03194 9e-118 paiB K Putative FMN-binding domain
HMGFFLMG_03195 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMGFFLMG_03196 3.7e-63 erpA S Belongs to the HesB IscA family
HMGFFLMG_03197 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMGFFLMG_03198 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HMGFFLMG_03199 3.2e-39 yuzB S Belongs to the UPF0349 family
HMGFFLMG_03200 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HMGFFLMG_03201 3.5e-57 yuzD S protein conserved in bacteria
HMGFFLMG_03202 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HMGFFLMG_03203 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HMGFFLMG_03204 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMGFFLMG_03205 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HMGFFLMG_03206 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
HMGFFLMG_03207 2e-199 yutH S Spore coat protein
HMGFFLMG_03208 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HMGFFLMG_03209 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMGFFLMG_03210 1e-75 yutE S Protein of unknown function DUF86
HMGFFLMG_03211 9.7e-48 yutD S protein conserved in bacteria
HMGFFLMG_03212 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HMGFFLMG_03213 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HMGFFLMG_03214 4.5e-196 lytH M Peptidase, M23
HMGFFLMG_03215 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
HMGFFLMG_03216 4.8e-48 yunC S Domain of unknown function (DUF1805)
HMGFFLMG_03217 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMGFFLMG_03218 2e-141 yunE S membrane transporter protein
HMGFFLMG_03219 4.3e-171 yunF S Protein of unknown function DUF72
HMGFFLMG_03220 3e-62 yunG
HMGFFLMG_03221 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HMGFFLMG_03222 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
HMGFFLMG_03223 2.1e-236 pbuX F Permease family
HMGFFLMG_03224 1.3e-224 pbuX F xanthine
HMGFFLMG_03225 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HMGFFLMG_03226 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HMGFFLMG_03227 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HMGFFLMG_03228 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HMGFFLMG_03229 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HMGFFLMG_03230 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HMGFFLMG_03231 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HMGFFLMG_03233 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HMGFFLMG_03234 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HMGFFLMG_03235 2.4e-169 bsn L Ribonuclease
HMGFFLMG_03236 1.2e-205 msmX P Belongs to the ABC transporter superfamily
HMGFFLMG_03237 1.1e-135 yurK K UTRA
HMGFFLMG_03238 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HMGFFLMG_03239 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
HMGFFLMG_03240 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
HMGFFLMG_03241 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HMGFFLMG_03242 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HMGFFLMG_03243 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HMGFFLMG_03244 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HMGFFLMG_03246 1e-41
HMGFFLMG_03247 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMGFFLMG_03248 3.5e-271 sufB O FeS cluster assembly
HMGFFLMG_03249 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HMGFFLMG_03250 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMGFFLMG_03251 1.4e-245 sufD O assembly protein SufD
HMGFFLMG_03252 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HMGFFLMG_03253 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HMGFFLMG_03254 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
HMGFFLMG_03255 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HMGFFLMG_03256 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMGFFLMG_03257 2.4e-56 yusD S SCP-2 sterol transfer family
HMGFFLMG_03258 5.6e-55 traF CO Thioredoxin
HMGFFLMG_03259 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HMGFFLMG_03260 1.1e-39 yusG S Protein of unknown function (DUF2553)
HMGFFLMG_03261 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HMGFFLMG_03262 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HMGFFLMG_03263 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HMGFFLMG_03264 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HMGFFLMG_03265 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HMGFFLMG_03266 4.7e-09 S YuzL-like protein
HMGFFLMG_03267 2.2e-165 fadM E Proline dehydrogenase
HMGFFLMG_03268 5.1e-40
HMGFFLMG_03269 3.2e-53 yusN M Coat F domain
HMGFFLMG_03270 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
HMGFFLMG_03271 3.8e-293 yusP P Major facilitator superfamily
HMGFFLMG_03272 8.4e-66 yusQ S Tautomerase enzyme
HMGFFLMG_03273 1e-63 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_03274 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_03275 2.7e-160 yusT K LysR substrate binding domain
HMGFFLMG_03276 3.8e-47 yusU S Protein of unknown function (DUF2573)
HMGFFLMG_03277 1e-153 yusV 3.6.3.34 HP ABC transporter
HMGFFLMG_03278 5.6e-66 S YusW-like protein
HMGFFLMG_03279 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
HMGFFLMG_03280 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
HMGFFLMG_03281 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_03282 1.2e-79 dps P Ferritin-like domain
HMGFFLMG_03283 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMGFFLMG_03284 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_03285 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HMGFFLMG_03286 4.3e-158 yuxN K Transcriptional regulator
HMGFFLMG_03287 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMGFFLMG_03288 2.3e-24 S Protein of unknown function (DUF3970)
HMGFFLMG_03289 2.2e-247 gerAA EG Spore germination protein
HMGFFLMG_03290 9.1e-198 gerAB E Spore germination protein
HMGFFLMG_03291 4.6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
HMGFFLMG_03292 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMGFFLMG_03293 5.5e-187 vraS 2.7.13.3 T Histidine kinase
HMGFFLMG_03294 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HMGFFLMG_03295 9.3e-129 liaG S Putative adhesin
HMGFFLMG_03296 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HMGFFLMG_03297 5.6e-62 liaI S membrane
HMGFFLMG_03298 4.8e-227 yvqJ EGP Major facilitator Superfamily
HMGFFLMG_03299 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
HMGFFLMG_03300 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HMGFFLMG_03301 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_03302 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HMGFFLMG_03303 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_03304 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HMGFFLMG_03305 0.0 T PhoQ Sensor
HMGFFLMG_03306 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_03307 3.6e-22
HMGFFLMG_03308 1.8e-96 yvrI K RNA polymerase
HMGFFLMG_03309 2.4e-19 S YvrJ protein family
HMGFFLMG_03310 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
HMGFFLMG_03311 1.3e-64 yvrL S Regulatory protein YrvL
HMGFFLMG_03312 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HMGFFLMG_03313 7.1e-124 macB V ABC transporter, ATP-binding protein
HMGFFLMG_03314 4.8e-176 M Efflux transporter rnd family, mfp subunit
HMGFFLMG_03315 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HMGFFLMG_03316 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_03317 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMGFFLMG_03318 2.1e-179 fhuD P ABC transporter
HMGFFLMG_03320 2.6e-237 yvsH E Arginine ornithine antiporter
HMGFFLMG_03321 6.5e-16 S Small spore protein J (Spore_SspJ)
HMGFFLMG_03322 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HMGFFLMG_03323 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HMGFFLMG_03324 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HMGFFLMG_03325 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HMGFFLMG_03326 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
HMGFFLMG_03327 9.1e-158 yvgN S reductase
HMGFFLMG_03328 5.4e-86 yvgO
HMGFFLMG_03329 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HMGFFLMG_03330 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HMGFFLMG_03331 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HMGFFLMG_03332 0.0 helD 3.6.4.12 L DNA helicase
HMGFFLMG_03333 4.1e-107 yvgT S membrane
HMGFFLMG_03334 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HMGFFLMG_03335 1.6e-104 bdbD O Thioredoxin
HMGFFLMG_03336 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HMGFFLMG_03337 0.0 copA 3.6.3.54 P P-type ATPase
HMGFFLMG_03338 1.5e-29 copZ P Copper resistance protein CopZ
HMGFFLMG_03339 2.2e-48 csoR S transcriptional
HMGFFLMG_03340 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
HMGFFLMG_03341 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMGFFLMG_03342 0.0 yvaC S Fusaric acid resistance protein-like
HMGFFLMG_03343 5.7e-73 yvaD S Family of unknown function (DUF5360)
HMGFFLMG_03344 2.8e-55 yvaE P Small Multidrug Resistance protein
HMGFFLMG_03345 4.1e-101 K Bacterial regulatory proteins, tetR family
HMGFFLMG_03346 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_03348 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HMGFFLMG_03349 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMGFFLMG_03350 5.6e-143 est 3.1.1.1 S Carboxylesterase
HMGFFLMG_03351 2.4e-23 secG U Preprotein translocase subunit SecG
HMGFFLMG_03352 3.7e-153 yvaM S Serine aminopeptidase, S33
HMGFFLMG_03353 7.5e-36 yvzC K Transcriptional
HMGFFLMG_03354 4e-69 K transcriptional
HMGFFLMG_03355 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
HMGFFLMG_03356 2.2e-54 yodB K transcriptional
HMGFFLMG_03357 4.2e-226 NT chemotaxis protein
HMGFFLMG_03358 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HMGFFLMG_03359 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMGFFLMG_03360 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HMGFFLMG_03361 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HMGFFLMG_03362 8.7e-61 yvbF K Belongs to the GbsR family
HMGFFLMG_03363 7.9e-13 S Sporulation delaying protein SdpA
HMGFFLMG_03364 7.6e-172
HMGFFLMG_03365 4.4e-08
HMGFFLMG_03366 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HMGFFLMG_03367 4.5e-45 sdpR K transcriptional
HMGFFLMG_03368 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HMGFFLMG_03369 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HMGFFLMG_03370 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HMGFFLMG_03371 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HMGFFLMG_03372 1.4e-98 yvbF K Belongs to the GbsR family
HMGFFLMG_03373 6.4e-103 yvbG U UPF0056 membrane protein
HMGFFLMG_03374 8.6e-113 yvbH S YvbH-like oligomerisation region
HMGFFLMG_03375 4.2e-124 exoY M Membrane
HMGFFLMG_03376 0.0 tcaA S response to antibiotic
HMGFFLMG_03377 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
HMGFFLMG_03378 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMGFFLMG_03379 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HMGFFLMG_03380 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMGFFLMG_03381 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMGFFLMG_03382 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMGFFLMG_03383 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HMGFFLMG_03384 1.6e-252 araE EGP Major facilitator Superfamily
HMGFFLMG_03385 5.5e-203 araR K transcriptional
HMGFFLMG_03386 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMGFFLMG_03387 3.9e-159 yvbU K Transcriptional regulator
HMGFFLMG_03388 8.5e-157 yvbV EG EamA-like transporter family
HMGFFLMG_03389 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HMGFFLMG_03390 4.3e-197 yvbX S Glycosyl hydrolase
HMGFFLMG_03391 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HMGFFLMG_03392 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HMGFFLMG_03393 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HMGFFLMG_03394 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMGFFLMG_03395 8.9e-201 desK 2.7.13.3 T Histidine kinase
HMGFFLMG_03396 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
HMGFFLMG_03397 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HMGFFLMG_03398 2.6e-157 rsbQ S Alpha/beta hydrolase family
HMGFFLMG_03399 1.4e-199 rsbU 3.1.3.3 T response regulator
HMGFFLMG_03400 2.6e-252 galA 3.2.1.89 G arabinogalactan
HMGFFLMG_03401 0.0 lacA 3.2.1.23 G beta-galactosidase
HMGFFLMG_03402 3.2e-150 ganQ P transport
HMGFFLMG_03403 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HMGFFLMG_03404 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
HMGFFLMG_03405 1.8e-184 lacR K Transcriptional regulator
HMGFFLMG_03406 6.6e-111 yvfI K COG2186 Transcriptional regulators
HMGFFLMG_03407 1.4e-309 yvfH C L-lactate permease
HMGFFLMG_03408 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HMGFFLMG_03409 1e-31 yvfG S YvfG protein
HMGFFLMG_03410 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
HMGFFLMG_03411 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HMGFFLMG_03412 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HMGFFLMG_03413 1.1e-46 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HMGFFLMG_03414 1.2e-35 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HMGFFLMG_03415 1.6e-81 S KNTase C-terminal domain
HMGFFLMG_03416 1.8e-195 epsF GT4 M Glycosyl transferases group 1
HMGFFLMG_03417 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HMGFFLMG_03418 2e-224 epsD GT4 M Glycosyl transferase 4-like
HMGFFLMG_03419 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HMGFFLMG_03420 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HMGFFLMG_03421 4e-122 ywqC M biosynthesis protein
HMGFFLMG_03422 5.7e-77 slr K transcriptional
HMGFFLMG_03423 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HMGFFLMG_03425 4.6e-93 padC Q Phenolic acid decarboxylase
HMGFFLMG_03426 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
HMGFFLMG_03427 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HMGFFLMG_03428 9.6e-266 pbpE V Beta-lactamase
HMGFFLMG_03429 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HMGFFLMG_03430 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HMGFFLMG_03431 1.8e-295 yveA E amino acid
HMGFFLMG_03432 2.6e-106 yvdT K Transcriptional regulator
HMGFFLMG_03433 6.7e-51 ykkC P Small Multidrug Resistance protein
HMGFFLMG_03434 4.1e-50 sugE P Small Multidrug Resistance protein
HMGFFLMG_03435 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
HMGFFLMG_03436 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
HMGFFLMG_03437 1.5e-183 S Patatin-like phospholipase
HMGFFLMG_03439 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMGFFLMG_03440 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HMGFFLMG_03441 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HMGFFLMG_03442 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HMGFFLMG_03443 1.2e-158 malA S Protein of unknown function (DUF1189)
HMGFFLMG_03444 7.8e-149 malD P transport
HMGFFLMG_03445 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
HMGFFLMG_03446 3.7e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HMGFFLMG_03447 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HMGFFLMG_03448 3.6e-174 yvdE K Transcriptional regulator
HMGFFLMG_03449 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HMGFFLMG_03450 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HMGFFLMG_03451 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HMGFFLMG_03452 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HMGFFLMG_03453 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMGFFLMG_03454 0.0 yxdM V ABC transporter (permease)
HMGFFLMG_03455 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HMGFFLMG_03456 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HMGFFLMG_03457 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_03458 1.8e-33
HMGFFLMG_03459 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HMGFFLMG_03460 1.6e-36 crh G Phosphocarrier protein Chr
HMGFFLMG_03461 1.4e-170 whiA K May be required for sporulation
HMGFFLMG_03462 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMGFFLMG_03463 5.7e-166 rapZ S Displays ATPase and GTPase activities
HMGFFLMG_03464 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HMGFFLMG_03465 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMGFFLMG_03466 1.4e-102 usp CBM50 M protein conserved in bacteria
HMGFFLMG_03467 2.4e-278 S COG0457 FOG TPR repeat
HMGFFLMG_03468 0.0 msbA2 3.6.3.44 V ABC transporter
HMGFFLMG_03470 0.0
HMGFFLMG_03471 4.6e-121
HMGFFLMG_03472 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HMGFFLMG_03473 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HMGFFLMG_03474 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMGFFLMG_03475 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMGFFLMG_03476 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HMGFFLMG_03477 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMGFFLMG_03478 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HMGFFLMG_03479 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMGFFLMG_03480 4.5e-140 yvpB NU protein conserved in bacteria
HMGFFLMG_03481 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HMGFFLMG_03482 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HMGFFLMG_03483 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HMGFFLMG_03484 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
HMGFFLMG_03485 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMGFFLMG_03486 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMGFFLMG_03487 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMGFFLMG_03488 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMGFFLMG_03489 3.6e-134 yvoA K transcriptional
HMGFFLMG_03490 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HMGFFLMG_03491 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
HMGFFLMG_03492 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
HMGFFLMG_03493 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HMGFFLMG_03494 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
HMGFFLMG_03495 2.7e-203 yvmA EGP Major facilitator Superfamily
HMGFFLMG_03496 1.2e-50 yvlD S Membrane
HMGFFLMG_03497 2.6e-26 pspB KT PspC domain
HMGFFLMG_03498 3.4e-168 yvlB S Putative adhesin
HMGFFLMG_03499 8e-49 yvlA
HMGFFLMG_03500 6.7e-34 yvkN
HMGFFLMG_03501 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HMGFFLMG_03502 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMGFFLMG_03503 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMGFFLMG_03504 1.2e-30 csbA S protein conserved in bacteria
HMGFFLMG_03505 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HMGFFLMG_03506 7e-101 yvkB K Transcriptional regulator
HMGFFLMG_03507 7.9e-228 yvkA EGP Major facilitator Superfamily
HMGFFLMG_03508 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMGFFLMG_03509 1e-54 swrA S Swarming motility protein
HMGFFLMG_03510 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HMGFFLMG_03511 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HMGFFLMG_03512 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HMGFFLMG_03513 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HMGFFLMG_03514 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HMGFFLMG_03515 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMGFFLMG_03516 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMGFFLMG_03517 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMGFFLMG_03518 2.8e-66
HMGFFLMG_03519 1.9e-08 fliT S bacterial-type flagellum organization
HMGFFLMG_03520 2.9e-69 fliS N flagellar protein FliS
HMGFFLMG_03521 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HMGFFLMG_03522 6.1e-57 flaG N flagellar protein FlaG
HMGFFLMG_03523 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HMGFFLMG_03524 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HMGFFLMG_03525 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HMGFFLMG_03526 2.6e-50 yviE
HMGFFLMG_03527 1.1e-156 flgL N Belongs to the bacterial flagellin family
HMGFFLMG_03528 1.2e-264 flgK N flagellar hook-associated protein
HMGFFLMG_03529 2.4e-78 flgN NOU FlgN protein
HMGFFLMG_03530 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
HMGFFLMG_03531 7e-74 yvyF S flagellar protein
HMGFFLMG_03532 2.7e-129 comFC S Phosphoribosyl transferase domain
HMGFFLMG_03533 5.7e-46 comFB S Late competence development protein ComFB
HMGFFLMG_03534 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HMGFFLMG_03535 7.3e-155 degV S protein conserved in bacteria
HMGFFLMG_03536 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HMGFFLMG_03537 1.9e-182 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HMGFFLMG_03538 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HMGFFLMG_03539 6e-163 yvhJ K Transcriptional regulator
HMGFFLMG_03540 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HMGFFLMG_03541 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HMGFFLMG_03542 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HMGFFLMG_03543 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
HMGFFLMG_03544 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
HMGFFLMG_03545 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMGFFLMG_03546 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HMGFFLMG_03547 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMGFFLMG_03548 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HMGFFLMG_03549 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HMGFFLMG_03550 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HMGFFLMG_03551 6e-38
HMGFFLMG_03552 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HMGFFLMG_03553 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMGFFLMG_03554 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMGFFLMG_03555 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMGFFLMG_03556 8.1e-257 ggaA M Glycosyltransferase like family 2
HMGFFLMG_03558 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMGFFLMG_03559 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HMGFFLMG_03560 1.1e-150 tagG GM Transport permease protein
HMGFFLMG_03561 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HMGFFLMG_03562 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HMGFFLMG_03563 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HMGFFLMG_03564 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMGFFLMG_03565 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HMGFFLMG_03566 1.2e-260
HMGFFLMG_03567 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMGFFLMG_03568 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HMGFFLMG_03569 3.5e-266 gerBA EG Spore germination protein
HMGFFLMG_03570 7.5e-200 gerBB E Spore germination protein
HMGFFLMG_03571 7.6e-216 gerAC S Spore germination protein
HMGFFLMG_03572 1.9e-248 ywtG EGP Major facilitator Superfamily
HMGFFLMG_03573 8.4e-171 ywtF K Transcriptional regulator
HMGFFLMG_03574 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HMGFFLMG_03575 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HMGFFLMG_03576 3.6e-21 ywtC
HMGFFLMG_03577 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HMGFFLMG_03578 8.6e-70 pgsC S biosynthesis protein
HMGFFLMG_03579 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HMGFFLMG_03580 1.5e-180 rbsR K transcriptional
HMGFFLMG_03581 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMGFFLMG_03582 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HMGFFLMG_03583 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HMGFFLMG_03584 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HMGFFLMG_03585 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HMGFFLMG_03586 4.6e-94 batE T Sh3 type 3 domain protein
HMGFFLMG_03587 3.6e-48 ywsA S Protein of unknown function (DUF3892)
HMGFFLMG_03588 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HMGFFLMG_03589 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HMGFFLMG_03590 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HMGFFLMG_03591 1.1e-169 alsR K LysR substrate binding domain
HMGFFLMG_03592 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HMGFFLMG_03593 7.5e-126 ywrJ
HMGFFLMG_03594 7.6e-131 cotB
HMGFFLMG_03595 1.2e-210 cotH M Spore Coat
HMGFFLMG_03596 3.7e-12
HMGFFLMG_03597 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HMGFFLMG_03598 2.9e-54 S Domain of unknown function (DUF4181)
HMGFFLMG_03599 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HMGFFLMG_03600 2.1e-82 ywrC K Transcriptional regulator
HMGFFLMG_03601 2.4e-104 ywrB P Chromate transporter
HMGFFLMG_03602 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
HMGFFLMG_03604 2.7e-102 ywqN S NAD(P)H-dependent
HMGFFLMG_03605 2.9e-162 K Transcriptional regulator
HMGFFLMG_03606 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HMGFFLMG_03607 1.7e-52 S MORN repeat variant
HMGFFLMG_03608 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
HMGFFLMG_03609 1.3e-38 ywqI S Family of unknown function (DUF5344)
HMGFFLMG_03610 3.3e-15 S Domain of unknown function (DUF5082)
HMGFFLMG_03611 3.4e-154 ywqG S Domain of unknown function (DUF1963)
HMGFFLMG_03612 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HMGFFLMG_03613 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HMGFFLMG_03614 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HMGFFLMG_03615 2e-116 ywqC M biosynthesis protein
HMGFFLMG_03616 1.2e-17
HMGFFLMG_03617 3.8e-309 ywqB S SWIM zinc finger
HMGFFLMG_03618 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HMGFFLMG_03619 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HMGFFLMG_03620 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HMGFFLMG_03621 9.8e-58 ssbB L Single-stranded DNA-binding protein
HMGFFLMG_03622 1.3e-66 ywpG
HMGFFLMG_03623 1.1e-66 ywpF S YwpF-like protein
HMGFFLMG_03624 8e-51 srtA 3.4.22.70 M Sortase family
HMGFFLMG_03625 1.9e-153 ywpD T Histidine kinase
HMGFFLMG_03626 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMGFFLMG_03627 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMGFFLMG_03628 2.1e-199 S aspartate phosphatase
HMGFFLMG_03629 1.5e-141 flhP N flagellar basal body
HMGFFLMG_03630 6.9e-126 flhO N flagellar basal body
HMGFFLMG_03631 3.5e-180 mbl D Rod shape-determining protein
HMGFFLMG_03632 3e-44 spoIIID K Stage III sporulation protein D
HMGFFLMG_03633 2.1e-70 ywoH K COG1846 Transcriptional regulators
HMGFFLMG_03634 2.7e-211 ywoG EGP Major facilitator Superfamily
HMGFFLMG_03635 1.2e-231 ywoF P Right handed beta helix region
HMGFFLMG_03636 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HMGFFLMG_03637 4.4e-242 ywoD EGP Major facilitator superfamily
HMGFFLMG_03638 4e-104 phzA Q Isochorismatase family
HMGFFLMG_03639 1.2e-77
HMGFFLMG_03640 2.5e-225 amt P Ammonium transporter
HMGFFLMG_03641 1.6e-58 nrgB K Belongs to the P(II) protein family
HMGFFLMG_03642 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HMGFFLMG_03643 3.5e-73 ywnJ S VanZ like family
HMGFFLMG_03644 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HMGFFLMG_03645 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HMGFFLMG_03646 2.7e-14 ywnC S Family of unknown function (DUF5362)
HMGFFLMG_03647 2.2e-70 ywnF S Family of unknown function (DUF5392)
HMGFFLMG_03648 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMGFFLMG_03649 4.1e-144 mta K transcriptional
HMGFFLMG_03650 2.6e-59 ywnC S Family of unknown function (DUF5362)
HMGFFLMG_03651 1.6e-114 ywnB S NAD(P)H-binding
HMGFFLMG_03652 1.7e-64 ywnA K Transcriptional regulator
HMGFFLMG_03653 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HMGFFLMG_03654 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HMGFFLMG_03655 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HMGFFLMG_03657 3.8e-11 csbD K CsbD-like
HMGFFLMG_03658 3e-84 ywmF S Peptidase M50
HMGFFLMG_03659 1.3e-103 S response regulator aspartate phosphatase
HMGFFLMG_03660 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HMGFFLMG_03661 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HMGFFLMG_03663 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HMGFFLMG_03664 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HMGFFLMG_03665 2e-178 spoIID D Stage II sporulation protein D
HMGFFLMG_03666 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMGFFLMG_03667 1.6e-134 ywmB S TATA-box binding
HMGFFLMG_03668 1.3e-32 ywzB S membrane
HMGFFLMG_03669 4.3e-88 ywmA
HMGFFLMG_03670 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMGFFLMG_03671 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMGFFLMG_03672 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMGFFLMG_03673 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMGFFLMG_03674 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMGFFLMG_03675 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMGFFLMG_03676 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMGFFLMG_03677 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HMGFFLMG_03678 2.5e-62 atpI S ATP synthase
HMGFFLMG_03679 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMGFFLMG_03680 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMGFFLMG_03681 7.2e-95 ywlG S Belongs to the UPF0340 family
HMGFFLMG_03682 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HMGFFLMG_03683 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMGFFLMG_03684 1.7e-91 mntP P Probably functions as a manganese efflux pump
HMGFFLMG_03685 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMGFFLMG_03686 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HMGFFLMG_03687 6.1e-112 spoIIR S stage II sporulation protein R
HMGFFLMG_03688 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
HMGFFLMG_03690 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMGFFLMG_03691 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMGFFLMG_03692 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMGFFLMG_03693 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HMGFFLMG_03694 8.6e-160 ywkB S Membrane transport protein
HMGFFLMG_03695 0.0 sfcA 1.1.1.38 C malic enzyme
HMGFFLMG_03696 2.4e-104 tdk 2.7.1.21 F thymidine kinase
HMGFFLMG_03697 1.1e-32 rpmE J Binds the 23S rRNA
HMGFFLMG_03698 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HMGFFLMG_03699 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HMGFFLMG_03700 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMGFFLMG_03701 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HMGFFLMG_03702 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HMGFFLMG_03703 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HMGFFLMG_03704 2.4e-92 ywjG S Domain of unknown function (DUF2529)
HMGFFLMG_03705 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMGFFLMG_03706 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMGFFLMG_03707 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HMGFFLMG_03708 0.0 fadF C COG0247 Fe-S oxidoreductase
HMGFFLMG_03709 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HMGFFLMG_03710 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HMGFFLMG_03711 2.7e-42 ywjC
HMGFFLMG_03712 4.8e-96 ywjB H RibD C-terminal domain
HMGFFLMG_03713 0.0 ywjA V ABC transporter
HMGFFLMG_03714 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMGFFLMG_03715 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
HMGFFLMG_03716 2.4e-98 narJ 1.7.5.1 C nitrate reductase
HMGFFLMG_03717 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
HMGFFLMG_03718 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMGFFLMG_03719 7e-86 arfM T cyclic nucleotide binding
HMGFFLMG_03720 4.3e-140 ywiC S YwiC-like protein
HMGFFLMG_03721 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
HMGFFLMG_03722 9.8e-214 narK P COG2223 Nitrate nitrite transporter
HMGFFLMG_03723 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HMGFFLMG_03724 4.7e-73 ywiB S protein conserved in bacteria
HMGFFLMG_03725 1e-07 S Bacteriocin subtilosin A
HMGFFLMG_03726 2.6e-271 C Fe-S oxidoreductases
HMGFFLMG_03728 3.3e-132 cbiO V ABC transporter
HMGFFLMG_03729 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HMGFFLMG_03730 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
HMGFFLMG_03731 1.2e-249 L Peptidase, M16
HMGFFLMG_03733 2.9e-249 ywhL CO amine dehydrogenase activity
HMGFFLMG_03734 2.5e-205 ywhK CO amine dehydrogenase activity
HMGFFLMG_03735 2.3e-79 S aspartate phosphatase
HMGFFLMG_03737 1e-84 ywhH S Aminoacyl-tRNA editing domain
HMGFFLMG_03738 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HMGFFLMG_03739 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HMGFFLMG_03740 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMGFFLMG_03741 5.2e-95 ywhD S YwhD family
HMGFFLMG_03742 5.1e-119 ywhC S Peptidase family M50
HMGFFLMG_03743 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HMGFFLMG_03744 3.3e-71 ywhA K Transcriptional regulator
HMGFFLMG_03745 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMGFFLMG_03747 2.6e-242 mmr U Major Facilitator Superfamily
HMGFFLMG_03748 2.8e-79 yffB K Transcriptional regulator
HMGFFLMG_03749 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HMGFFLMG_03750 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HMGFFLMG_03751 3.1e-36 ywzC S Belongs to the UPF0741 family
HMGFFLMG_03752 1.6e-111 rsfA_1
HMGFFLMG_03753 5.2e-159 ywfM EG EamA-like transporter family
HMGFFLMG_03754 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HMGFFLMG_03755 9.2e-164 cysL K Transcriptional regulator
HMGFFLMG_03756 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HMGFFLMG_03757 1.1e-146 ywfI C May function as heme-dependent peroxidase
HMGFFLMG_03758 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
HMGFFLMG_03759 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HMGFFLMG_03760 2.9e-210 bacE EGP Major facilitator Superfamily
HMGFFLMG_03761 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HMGFFLMG_03762 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HMGFFLMG_03763 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HMGFFLMG_03764 3.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HMGFFLMG_03765 4.6e-206 ywfA EGP Major facilitator Superfamily
HMGFFLMG_03766 5.1e-251 lysP E amino acid
HMGFFLMG_03767 0.0 rocB E arginine degradation protein
HMGFFLMG_03768 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HMGFFLMG_03769 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HMGFFLMG_03770 1.8e-78
HMGFFLMG_03771 3.5e-87 spsL 5.1.3.13 M Spore Coat
HMGFFLMG_03772 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMGFFLMG_03773 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMGFFLMG_03774 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMGFFLMG_03775 1.7e-190 spsG M Spore Coat
HMGFFLMG_03776 9.7e-132 spsF M Spore Coat
HMGFFLMG_03777 3.2e-214 spsE 2.5.1.56 M acid synthase
HMGFFLMG_03778 4e-164 spsD 2.3.1.210 K Spore Coat
HMGFFLMG_03779 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
HMGFFLMG_03780 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
HMGFFLMG_03781 2.8e-145 spsA M Spore Coat
HMGFFLMG_03782 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HMGFFLMG_03783 4.3e-59 ywdK S small membrane protein
HMGFFLMG_03784 1.3e-238 ywdJ F Xanthine uracil
HMGFFLMG_03785 7.7e-49 ywdI S Family of unknown function (DUF5327)
HMGFFLMG_03786 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HMGFFLMG_03787 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMGFFLMG_03788 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HMGFFLMG_03790 1.4e-113 ywdD
HMGFFLMG_03791 1.3e-57 pex K Transcriptional regulator PadR-like family
HMGFFLMG_03792 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMGFFLMG_03793 2e-28 ywdA
HMGFFLMG_03794 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HMGFFLMG_03795 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMGFFLMG_03796 1e-139 focA P Formate/nitrite transporter
HMGFFLMG_03797 2.4e-150 sacT K transcriptional antiterminator
HMGFFLMG_03799 0.0 vpr O Belongs to the peptidase S8 family
HMGFFLMG_03800 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMGFFLMG_03801 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HMGFFLMG_03802 2.9e-202 rodA D Belongs to the SEDS family
HMGFFLMG_03803 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HMGFFLMG_03804 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HMGFFLMG_03805 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HMGFFLMG_03806 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HMGFFLMG_03807 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HMGFFLMG_03808 1e-35 ywzA S membrane
HMGFFLMG_03809 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HMGFFLMG_03810 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMGFFLMG_03811 9.5e-60 gtcA S GtrA-like protein
HMGFFLMG_03812 2.2e-122 ywcC K transcriptional regulator
HMGFFLMG_03814 9.8e-49 ywcB S Protein of unknown function, DUF485
HMGFFLMG_03815 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMGFFLMG_03816 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HMGFFLMG_03817 2.6e-225 ywbN P Dyp-type peroxidase family protein
HMGFFLMG_03818 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
HMGFFLMG_03819 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
HMGFFLMG_03820 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMGFFLMG_03821 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMGFFLMG_03822 4.3e-153 ywbI K Transcriptional regulator
HMGFFLMG_03823 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HMGFFLMG_03824 2.3e-111 ywbG M effector of murein hydrolase
HMGFFLMG_03825 1.9e-209 ywbF EGP Major facilitator Superfamily
HMGFFLMG_03826 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
HMGFFLMG_03827 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
HMGFFLMG_03828 4.4e-67 ywbC 4.4.1.5 E glyoxalase
HMGFFLMG_03829 1.8e-127 ywbB S Protein of unknown function (DUF2711)
HMGFFLMG_03830 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMGFFLMG_03831 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
HMGFFLMG_03832 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMGFFLMG_03833 4e-153 sacY K transcriptional antiterminator
HMGFFLMG_03834 7e-169 gspA M General stress
HMGFFLMG_03835 1.7e-128 ywaF S Integral membrane protein
HMGFFLMG_03836 8.1e-88 ywaE K Transcriptional regulator
HMGFFLMG_03837 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMGFFLMG_03838 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HMGFFLMG_03839 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HMGFFLMG_03840 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HMGFFLMG_03841 5e-14 S D-Ala-teichoic acid biosynthesis protein
HMGFFLMG_03842 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMGFFLMG_03843 1.2e-232 dltB M membrane protein involved in D-alanine export
HMGFFLMG_03844 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMGFFLMG_03845 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMGFFLMG_03846 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_03847 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HMGFFLMG_03848 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HMGFFLMG_03849 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HMGFFLMG_03850 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMGFFLMG_03851 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HMGFFLMG_03852 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HMGFFLMG_03853 1.1e-19 yxzF
HMGFFLMG_03854 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HMGFFLMG_03855 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HMGFFLMG_03856 2.1e-216 yxlH EGP Major facilitator Superfamily
HMGFFLMG_03857 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HMGFFLMG_03858 5.1e-167 yxlF V ABC transporter, ATP-binding protein
HMGFFLMG_03859 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HMGFFLMG_03860 1.2e-31
HMGFFLMG_03861 3.9e-48 yxlC S Family of unknown function (DUF5345)
HMGFFLMG_03862 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HMGFFLMG_03863 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HMGFFLMG_03864 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMGFFLMG_03865 0.0 cydD V ATP-binding protein
HMGFFLMG_03866 0.0 cydD V ATP-binding
HMGFFLMG_03867 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HMGFFLMG_03868 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
HMGFFLMG_03869 1.5e-229 cimH C COG3493 Na citrate symporter
HMGFFLMG_03870 0.0 3.4.24.84 O Peptidase family M48
HMGFFLMG_03872 3e-156 yxkH G Polysaccharide deacetylase
HMGFFLMG_03873 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HMGFFLMG_03874 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
HMGFFLMG_03875 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMGFFLMG_03876 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMGFFLMG_03877 4.1e-73 yxkC S Domain of unknown function (DUF4352)
HMGFFLMG_03878 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMGFFLMG_03879 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
HMGFFLMG_03880 1.9e-166 yxjO K LysR substrate binding domain
HMGFFLMG_03881 2.4e-78 S Protein of unknown function (DUF1453)
HMGFFLMG_03882 1.5e-193 yxjM T Signal transduction histidine kinase
HMGFFLMG_03883 8.9e-116 K helix_turn_helix, Lux Regulon
HMGFFLMG_03884 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMGFFLMG_03887 1e-87 yxjI S LURP-one-related
HMGFFLMG_03888 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
HMGFFLMG_03889 1e-220 yxjG 2.1.1.14 E Methionine synthase
HMGFFLMG_03890 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HMGFFLMG_03891 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HMGFFLMG_03892 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HMGFFLMG_03893 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HMGFFLMG_03894 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
HMGFFLMG_03895 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HMGFFLMG_03896 1.2e-22 T Domain of unknown function (DUF4163)
HMGFFLMG_03897 2.7e-48 yxiS
HMGFFLMG_03898 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HMGFFLMG_03899 6.6e-224 citH C Citrate transporter
HMGFFLMG_03900 5e-144 exoK GH16 M licheninase activity
HMGFFLMG_03901 8.3e-151 licT K transcriptional antiterminator
HMGFFLMG_03902 6.6e-114
HMGFFLMG_03903 9.3e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
HMGFFLMG_03904 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HMGFFLMG_03905 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HMGFFLMG_03908 1.6e-48 yxiJ S YxiJ-like protein
HMGFFLMG_03909 1.2e-96 yxiI S Protein of unknown function (DUF2716)
HMGFFLMG_03910 3.8e-81
HMGFFLMG_03911 4.9e-46
HMGFFLMG_03912 3.7e-75 yxiG
HMGFFLMG_03913 6.4e-63
HMGFFLMG_03914 1.7e-84
HMGFFLMG_03915 1.5e-71 yxxG
HMGFFLMG_03916 0.0 wapA M COG3209 Rhs family protein
HMGFFLMG_03917 2.9e-168 yxxF EG EamA-like transporter family
HMGFFLMG_03918 1.1e-72 yxiE T Belongs to the universal stress protein A family
HMGFFLMG_03919 6.5e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMGFFLMG_03920 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMGFFLMG_03921 3.6e-51
HMGFFLMG_03922 2.2e-78 S SMI1 / KNR4 family
HMGFFLMG_03923 0.0 S nuclease activity
HMGFFLMG_03924 3.6e-39 yxiC S Family of unknown function (DUF5344)
HMGFFLMG_03925 2.1e-21 S Domain of unknown function (DUF5082)
HMGFFLMG_03926 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HMGFFLMG_03927 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HMGFFLMG_03928 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
HMGFFLMG_03929 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HMGFFLMG_03930 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HMGFFLMG_03931 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HMGFFLMG_03932 6.1e-252 lysP E amino acid
HMGFFLMG_03933 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HMGFFLMG_03934 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HMGFFLMG_03935 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMGFFLMG_03936 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HMGFFLMG_03937 3e-153 yxxB S Domain of Unknown Function (DUF1206)
HMGFFLMG_03938 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
HMGFFLMG_03939 2e-255 yxeQ S MmgE/PrpD family
HMGFFLMG_03940 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
HMGFFLMG_03941 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HMGFFLMG_03942 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
HMGFFLMG_03943 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HMGFFLMG_03944 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMGFFLMG_03945 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HMGFFLMG_03947 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HMGFFLMG_03948 6.2e-151 yidA S hydrolases of the HAD superfamily
HMGFFLMG_03951 1.3e-20 yxeE
HMGFFLMG_03952 1.9e-16 yxeD
HMGFFLMG_03953 8.5e-69
HMGFFLMG_03954 6e-177 fhuD P ABC transporter
HMGFFLMG_03955 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HMGFFLMG_03956 0.0 yxdM V ABC transporter (permease)
HMGFFLMG_03957 9.4e-141 yxdL V ABC transporter, ATP-binding protein
HMGFFLMG_03958 1.3e-182 T PhoQ Sensor
HMGFFLMG_03959 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_03960 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HMGFFLMG_03961 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HMGFFLMG_03962 2.3e-167 iolH G Xylose isomerase-like TIM barrel
HMGFFLMG_03963 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HMGFFLMG_03964 1.3e-235 iolF EGP Major facilitator Superfamily
HMGFFLMG_03965 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HMGFFLMG_03966 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HMGFFLMG_03967 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HMGFFLMG_03968 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HMGFFLMG_03969 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HMGFFLMG_03970 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HMGFFLMG_03971 3.7e-176 iolS C Aldo keto reductase
HMGFFLMG_03973 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HMGFFLMG_03974 2.3e-246 csbC EGP Major facilitator Superfamily
HMGFFLMG_03975 0.0 htpG O Molecular chaperone. Has ATPase activity
HMGFFLMG_03977 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
HMGFFLMG_03978 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
HMGFFLMG_03979 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HMGFFLMG_03980 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
HMGFFLMG_03981 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
HMGFFLMG_03982 3.3e-127 yxbB Q Met-10+ like-protein
HMGFFLMG_03983 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
HMGFFLMG_03984 1.1e-86 yxnB
HMGFFLMG_03985 0.0 asnB 6.3.5.4 E Asparagine synthase
HMGFFLMG_03986 7.6e-214 yxaM U MFS_1 like family
HMGFFLMG_03987 6.8e-93 S PQQ-like domain
HMGFFLMG_03988 3.5e-65 S Family of unknown function (DUF5391)
HMGFFLMG_03989 1.1e-75 yxaI S membrane protein domain
HMGFFLMG_03990 1.4e-228 P Protein of unknown function (DUF418)
HMGFFLMG_03991 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
HMGFFLMG_03992 7.1e-101 yxaF K Transcriptional regulator
HMGFFLMG_03993 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HMGFFLMG_03994 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HMGFFLMG_03995 5.2e-50 S LrgA family
HMGFFLMG_03996 2.6e-118 yxaC M effector of murein hydrolase
HMGFFLMG_03997 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
HMGFFLMG_03998 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMGFFLMG_03999 7.3e-127 gntR K transcriptional
HMGFFLMG_04000 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HMGFFLMG_04001 4.6e-144 gntP EG COG2610 H gluconate symporter and related permeases
HMGFFLMG_04002 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMGFFLMG_04003 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HMGFFLMG_04004 3.8e-287 ahpF O Alkyl hydroperoxide reductase
HMGFFLMG_04005 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMGFFLMG_04006 2.5e-19 bglF G phosphotransferase system
HMGFFLMG_04007 1.3e-128 yydK K Transcriptional regulator
HMGFFLMG_04008 7.6e-13
HMGFFLMG_04009 3.3e-119 S ABC-2 family transporter protein
HMGFFLMG_04010 1.8e-110 prrC P ABC transporter
HMGFFLMG_04011 8.4e-134 yydH O Peptidase M50
HMGFFLMG_04012 7.7e-185 S Radical SAM superfamily
HMGFFLMG_04013 8e-12
HMGFFLMG_04014 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HMGFFLMG_04015 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
HMGFFLMG_04016 3.5e-65
HMGFFLMG_04017 7.3e-280 S Calcineurin-like phosphoesterase
HMGFFLMG_04018 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMGFFLMG_04019 1.1e-09 S YyzF-like protein
HMGFFLMG_04020 4.2e-71
HMGFFLMG_04021 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HMGFFLMG_04023 2.1e-33 yycQ S Protein of unknown function (DUF2651)
HMGFFLMG_04024 1.6e-221 yycP
HMGFFLMG_04025 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HMGFFLMG_04026 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
HMGFFLMG_04027 5e-188 S aspartate phosphatase
HMGFFLMG_04029 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HMGFFLMG_04030 9.7e-261 rocE E amino acid
HMGFFLMG_04031 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HMGFFLMG_04032 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HMGFFLMG_04033 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMGFFLMG_04034 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HMGFFLMG_04035 7.3e-155 yycI S protein conserved in bacteria
HMGFFLMG_04036 3.6e-260 yycH S protein conserved in bacteria
HMGFFLMG_04037 0.0 vicK 2.7.13.3 T Histidine kinase
HMGFFLMG_04038 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HMGFFLMG_04043 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMGFFLMG_04044 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMGFFLMG_04045 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMGFFLMG_04046 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HMGFFLMG_04048 1.9e-15 yycC K YycC-like protein
HMGFFLMG_04049 8.4e-221 yeaN P COG2807 Cyanate permease
HMGFFLMG_04050 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMGFFLMG_04051 2.2e-73 rplI J binds to the 23S rRNA
HMGFFLMG_04052 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMGFFLMG_04053 2.9e-160 yybS S membrane
HMGFFLMG_04055 3.9e-84 cotF M Spore coat protein
HMGFFLMG_04056 1.4e-68 ydeP3 K Transcriptional regulator
HMGFFLMG_04057 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HMGFFLMG_04058 1.3e-70
HMGFFLMG_04060 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HMGFFLMG_04061 1e-16
HMGFFLMG_04062 1.3e-78 yybN S Protein of unknown function (DUF2712)
HMGFFLMG_04063 4.1e-125
HMGFFLMG_04064 9e-122
HMGFFLMG_04065 2e-127 S Protein of unknown function (DUF2705)
HMGFFLMG_04066 2.6e-115 V ATPases associated with a variety of cellular activities
HMGFFLMG_04067 6.2e-132
HMGFFLMG_04068 5.9e-67 yybH S SnoaL-like domain
HMGFFLMG_04069 3e-124 yybG S Pentapeptide repeat-containing protein
HMGFFLMG_04070 3.2e-220 ynfM EGP Major facilitator Superfamily
HMGFFLMG_04071 2.1e-165 yybE K Transcriptional regulator
HMGFFLMG_04072 2e-79 yjcF S Acetyltransferase (GNAT) domain
HMGFFLMG_04073 2.7e-77 yybC
HMGFFLMG_04074 3e-127 S Metallo-beta-lactamase superfamily
HMGFFLMG_04075 5.6e-77 yybA 2.3.1.57 K transcriptional
HMGFFLMG_04076 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
HMGFFLMG_04077 1.5e-101 yyaS S Membrane
HMGFFLMG_04078 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
HMGFFLMG_04079 5.4e-67 yyaQ S YjbR
HMGFFLMG_04080 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
HMGFFLMG_04081 1.7e-249 tetL EGP Major facilitator Superfamily
HMGFFLMG_04082 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
HMGFFLMG_04083 5.1e-61 yyaN K MerR HTH family regulatory protein
HMGFFLMG_04084 3.3e-161 yyaM EG EamA-like transporter family
HMGFFLMG_04085 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HMGFFLMG_04086 9.5e-169 yyaK S CAAX protease self-immunity
HMGFFLMG_04087 2.8e-241 EGP Major facilitator superfamily
HMGFFLMG_04088 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HMGFFLMG_04089 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMGFFLMG_04090 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HMGFFLMG_04091 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
HMGFFLMG_04092 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMGFFLMG_04093 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMGFFLMG_04094 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HMGFFLMG_04095 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMGFFLMG_04096 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMGFFLMG_04097 2.3e-33 yyzM S protein conserved in bacteria
HMGFFLMG_04098 8.1e-177 yyaD S Membrane
HMGFFLMG_04099 1.6e-111 yyaC S Sporulation protein YyaC
HMGFFLMG_04100 2.1e-149 spo0J K Belongs to the ParB family
HMGFFLMG_04101 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HMGFFLMG_04102 1.5e-74 S Bacterial PH domain
HMGFFLMG_04103 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HMGFFLMG_04104 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HMGFFLMG_04105 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMGFFLMG_04106 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMGFFLMG_04107 6.5e-108 jag S single-stranded nucleic acid binding R3H
HMGFFLMG_04108 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMGFFLMG_04109 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)