ORF_ID e_value Gene_name EC_number CAZy COGs Description
FLDIGELM_00001 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLDIGELM_00002 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FLDIGELM_00003 1.8e-37 yaaB S Domain of unknown function (DUF370)
FLDIGELM_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FLDIGELM_00005 2.4e-33 yaaA S S4 domain
FLDIGELM_00006 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FLDIGELM_00007 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FLDIGELM_00008 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
FLDIGELM_00009 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FLDIGELM_00010 6.5e-108 jag S single-stranded nucleic acid binding R3H
FLDIGELM_00011 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FLDIGELM_00012 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
FLDIGELM_00013 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
FLDIGELM_00014 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
FLDIGELM_00015 1.9e-74 S Bacterial PH domain
FLDIGELM_00016 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
FLDIGELM_00017 5.9e-118 spo0J K Belongs to the ParB family
FLDIGELM_00018 1.6e-111 yyaC S Sporulation protein YyaC
FLDIGELM_00019 8.1e-177 yyaD S Membrane
FLDIGELM_00020 2.3e-33 yyzM S protein conserved in bacteria
FLDIGELM_00021 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FLDIGELM_00022 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FLDIGELM_00023 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
FLDIGELM_00024 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FLDIGELM_00025 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FLDIGELM_00026 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
FLDIGELM_00027 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
FLDIGELM_00028 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FLDIGELM_00029 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
FLDIGELM_00030 3.8e-246 EGP Major facilitator superfamily
FLDIGELM_00031 9.5e-169 yyaK S CAAX protease self-immunity
FLDIGELM_00032 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
FLDIGELM_00033 1.7e-249 tetL EGP Major facilitator Superfamily
FLDIGELM_00034 3.3e-103 yyaP 1.5.1.3 H RibD C-terminal domain
FLDIGELM_00035 3.5e-66 yyaQ S YjbR
FLDIGELM_00036 2.4e-92 yyaR K Acetyltransferase (GNAT) domain
FLDIGELM_00037 5.5e-96 yyaS S Membrane
FLDIGELM_00038 2.4e-72 yjcF S Acetyltransferase (GNAT) domain
FLDIGELM_00039 5.6e-77 yybA 2.3.1.57 K transcriptional
FLDIGELM_00040 1.4e-124 S Metallo-beta-lactamase superfamily
FLDIGELM_00041 2.3e-73 yybC
FLDIGELM_00042 1.1e-77 yjcF S Acetyltransferase (GNAT) domain
FLDIGELM_00043 6.9e-164 yybE K Transcriptional regulator
FLDIGELM_00044 3.2e-220 ynfM EGP Major facilitator Superfamily
FLDIGELM_00045 1.6e-122 yybG S Pentapeptide repeat-containing protein
FLDIGELM_00046 8.6e-66 yybH S SnoaL-like domain
FLDIGELM_00047 2.8e-124
FLDIGELM_00048 2.2e-110 K TipAS antibiotic-recognition domain
FLDIGELM_00049 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
FLDIGELM_00051 1.6e-60
FLDIGELM_00052 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
FLDIGELM_00053 7.5e-67 ydeP3 K Transcriptional regulator
FLDIGELM_00054 3.9e-84 cotF M Spore coat protein
FLDIGELM_00056 2.9e-160 yybS S membrane
FLDIGELM_00057 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
FLDIGELM_00058 2.2e-73 rplI J binds to the 23S rRNA
FLDIGELM_00059 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FLDIGELM_00060 2.5e-220 yeaN P COG2807 Cyanate permease
FLDIGELM_00061 1.9e-15 yycC K YycC-like protein
FLDIGELM_00063 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
FLDIGELM_00064 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
FLDIGELM_00065 4.4e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FLDIGELM_00066 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FLDIGELM_00071 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_00072 0.0 vicK 2.7.13.3 T Histidine kinase
FLDIGELM_00073 3.4e-258 yycH S protein conserved in bacteria
FLDIGELM_00074 1.8e-153 yycI S protein conserved in bacteria
FLDIGELM_00075 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
FLDIGELM_00076 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLDIGELM_00077 2.7e-24 S Peptidase propeptide and YPEB domain
FLDIGELM_00078 4e-74 S Peptidase propeptide and YPEB domain
FLDIGELM_00079 1.5e-94 K PFAM response regulator receiver
FLDIGELM_00080 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
FLDIGELM_00081 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
FLDIGELM_00082 1.2e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
FLDIGELM_00083 4.8e-260 rocE E amino acid
FLDIGELM_00084 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
FLDIGELM_00086 1.2e-186 S aspartate phosphatase
FLDIGELM_00087 2.2e-84 yycN 2.3.1.128 K Acetyltransferase
FLDIGELM_00088 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
FLDIGELM_00089 1.6e-221 yycP
FLDIGELM_00090 2.1e-33 yycQ S Protein of unknown function (DUF2651)
FLDIGELM_00092 6.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
FLDIGELM_00093 4.2e-71
FLDIGELM_00094 1.1e-09 S YyzF-like protein
FLDIGELM_00095 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FLDIGELM_00096 7.3e-280 S Calcineurin-like phosphoesterase
FLDIGELM_00097 3.5e-65
FLDIGELM_00098 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
FLDIGELM_00099 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
FLDIGELM_00100 2.3e-11
FLDIGELM_00101 1.7e-184 S Radical SAM superfamily
FLDIGELM_00102 1.4e-133 yydH O Peptidase M50
FLDIGELM_00103 4.1e-110 prrC P ABC transporter
FLDIGELM_00104 8.9e-117 S ABC-2 family transporter protein
FLDIGELM_00105 7.1e-11
FLDIGELM_00106 3e-125 yydK K Transcriptional regulator
FLDIGELM_00107 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
FLDIGELM_00108 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FLDIGELM_00109 1.9e-286 ahpF O Alkyl hydroperoxide reductase
FLDIGELM_00110 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
FLDIGELM_00111 1.8e-270 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FLDIGELM_00112 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
FLDIGELM_00113 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
FLDIGELM_00114 2.8e-126 gntR K transcriptional
FLDIGELM_00115 6.6e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
FLDIGELM_00116 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
FLDIGELM_00117 1.3e-117 yxaC M effector of murein hydrolase
FLDIGELM_00118 5.2e-50 S LrgA family
FLDIGELM_00119 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
FLDIGELM_00120 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_00121 7.1e-101 yxaF K Transcriptional regulator
FLDIGELM_00122 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
FLDIGELM_00123 1.4e-228 P Protein of unknown function (DUF418)
FLDIGELM_00124 1.1e-75 yxaI S membrane protein domain
FLDIGELM_00125 3.5e-65 S Family of unknown function (DUF5391)
FLDIGELM_00126 6.8e-93 S PQQ-like domain
FLDIGELM_00127 7.6e-214 yxaM U MFS_1 like family
FLDIGELM_00128 0.0 asnB 6.3.5.4 E Asparagine synthase
FLDIGELM_00129 1.1e-86 yxnB
FLDIGELM_00130 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
FLDIGELM_00131 3.3e-127 yxbB Q Met-10+ like-protein
FLDIGELM_00132 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
FLDIGELM_00133 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
FLDIGELM_00134 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
FLDIGELM_00135 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
FLDIGELM_00136 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
FLDIGELM_00138 0.0 htpG O Molecular chaperone. Has ATPase activity
FLDIGELM_00139 2.3e-246 csbC EGP Major facilitator Superfamily
FLDIGELM_00140 8.3e-48 yxcD S Protein of unknown function (DUF2653)
FLDIGELM_00142 3.7e-176 iolS C Aldo keto reductase
FLDIGELM_00143 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
FLDIGELM_00144 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FLDIGELM_00145 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
FLDIGELM_00146 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
FLDIGELM_00147 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
FLDIGELM_00148 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
FLDIGELM_00149 1.3e-235 iolF EGP Major facilitator Superfamily
FLDIGELM_00150 1.4e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
FLDIGELM_00151 8.6e-167 iolH G Xylose isomerase-like TIM barrel
FLDIGELM_00152 1.2e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
FLDIGELM_00153 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
FLDIGELM_00154 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_00155 1.3e-182 T PhoQ Sensor
FLDIGELM_00156 9.4e-141 yxdL V ABC transporter, ATP-binding protein
FLDIGELM_00157 0.0 yxdM V ABC transporter (permease)
FLDIGELM_00158 1.5e-58 yxeA S Protein of unknown function (DUF1093)
FLDIGELM_00159 6e-177 fhuD P ABC transporter
FLDIGELM_00160 8.5e-69
FLDIGELM_00161 1.9e-16 yxeD
FLDIGELM_00162 1.3e-20 yxeE
FLDIGELM_00165 6.2e-151 yidA S hydrolases of the HAD superfamily
FLDIGELM_00166 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
FLDIGELM_00168 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLDIGELM_00169 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FLDIGELM_00170 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
FLDIGELM_00171 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
FLDIGELM_00172 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
FLDIGELM_00173 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
FLDIGELM_00174 2e-255 yxeQ S MmgE/PrpD family
FLDIGELM_00175 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
FLDIGELM_00176 4.1e-112 yxxB S Domain of Unknown Function (DUF1206)
FLDIGELM_00177 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
FLDIGELM_00178 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FLDIGELM_00179 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLDIGELM_00180 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
FLDIGELM_00181 3.4e-250 lysP E amino acid
FLDIGELM_00182 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
FLDIGELM_00183 3.9e-237 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
FLDIGELM_00184 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FLDIGELM_00185 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
FLDIGELM_00186 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
FLDIGELM_00187 1.9e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
FLDIGELM_00188 4.6e-21 S Domain of unknown function (DUF5082)
FLDIGELM_00189 1.8e-38 yxiC S Family of unknown function (DUF5344)
FLDIGELM_00190 0.0 S nuclease activity
FLDIGELM_00191 2.2e-78 S SMI1 / KNR4 family
FLDIGELM_00192 3.6e-51
FLDIGELM_00193 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FLDIGELM_00194 1.1e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FLDIGELM_00195 1.1e-72 yxiE T Belongs to the universal stress protein A family
FLDIGELM_00196 2.9e-168 yxxF EG EamA-like transporter family
FLDIGELM_00197 0.0 wapA M COG3209 Rhs family protein
FLDIGELM_00198 1.5e-71 yxxG
FLDIGELM_00199 1.7e-84
FLDIGELM_00200 6.4e-63
FLDIGELM_00201 3.7e-75 yxiG
FLDIGELM_00202 4.9e-46
FLDIGELM_00203 3.8e-81
FLDIGELM_00204 1.2e-96 yxiI S Protein of unknown function (DUF2716)
FLDIGELM_00205 1.6e-48 yxiJ S YxiJ-like protein
FLDIGELM_00208 2.7e-216 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
FLDIGELM_00209 1.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
FLDIGELM_00210 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
FLDIGELM_00211 2e-110
FLDIGELM_00212 8.3e-151 licT K transcriptional antiterminator
FLDIGELM_00213 3.3e-143 exoK GH16 M licheninase activity
FLDIGELM_00214 6.6e-224 citH C Citrate transporter
FLDIGELM_00215 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
FLDIGELM_00216 3e-47 yxiS
FLDIGELM_00217 4e-103 T Domain of unknown function (DUF4163)
FLDIGELM_00218 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLDIGELM_00219 1.4e-141 rlmA 2.1.1.187 Q Methyltransferase domain
FLDIGELM_00220 4.4e-253 yxjC EG COG2610 H gluconate symporter and related permeases
FLDIGELM_00221 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FLDIGELM_00222 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
FLDIGELM_00223 2.4e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
FLDIGELM_00224 3.1e-217 yxjG 2.1.1.14 E Methionine synthase
FLDIGELM_00225 1.6e-221 yxjG 2.1.1.14 E Methionine synthase
FLDIGELM_00226 1e-87 yxjI S LURP-one-related
FLDIGELM_00229 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
FLDIGELM_00230 8.9e-116 K helix_turn_helix, Lux Regulon
FLDIGELM_00231 6.1e-187 yxjM T Signal transduction histidine kinase
FLDIGELM_00232 3.4e-77 S Protein of unknown function (DUF1453)
FLDIGELM_00233 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
FLDIGELM_00234 1.1e-73 yxkC S Domain of unknown function (DUF4352)
FLDIGELM_00235 7.3e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLDIGELM_00236 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FLDIGELM_00237 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
FLDIGELM_00238 5.9e-205 msmK P Belongs to the ABC transporter superfamily
FLDIGELM_00239 3e-156 yxkH G Polysaccharide deacetylase
FLDIGELM_00241 0.0 3.4.24.84 O Peptidase family M48
FLDIGELM_00242 1.5e-229 cimH C COG3493 Na citrate symporter
FLDIGELM_00243 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
FLDIGELM_00244 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
FLDIGELM_00245 0.0 cydD V ATP-binding
FLDIGELM_00246 0.0 cydD V ATP-binding protein
FLDIGELM_00247 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FLDIGELM_00248 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
FLDIGELM_00249 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
FLDIGELM_00250 3.9e-48 yxlC S Family of unknown function (DUF5345)
FLDIGELM_00251 1.2e-31
FLDIGELM_00252 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
FLDIGELM_00253 1.1e-166 yxlF V ABC transporter, ATP-binding protein
FLDIGELM_00254 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FLDIGELM_00255 5.3e-215 yxlH EGP Major facilitator Superfamily
FLDIGELM_00256 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
FLDIGELM_00257 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
FLDIGELM_00258 1.1e-19 yxzF
FLDIGELM_00259 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
FLDIGELM_00260 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
FLDIGELM_00261 2.4e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FLDIGELM_00262 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
FLDIGELM_00263 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
FLDIGELM_00264 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
FLDIGELM_00265 1.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_00266 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FLDIGELM_00267 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDIGELM_00268 1.2e-232 dltB M membrane protein involved in D-alanine export
FLDIGELM_00269 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDIGELM_00270 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
FLDIGELM_00271 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
FLDIGELM_00272 5.7e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
FLDIGELM_00273 2.4e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLDIGELM_00274 4e-87 ywaE K Transcriptional regulator
FLDIGELM_00275 5.7e-124 ywaF S Integral membrane protein
FLDIGELM_00276 1e-167 gspA M General stress
FLDIGELM_00277 1.2e-152 sacY K transcriptional antiterminator
FLDIGELM_00278 2.2e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FLDIGELM_00279 3.3e-275 epr 3.4.21.62 O Belongs to the peptidase S8 family
FLDIGELM_00280 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FLDIGELM_00281 2.2e-125 ywbB S Protein of unknown function (DUF2711)
FLDIGELM_00282 9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FLDIGELM_00283 9.9e-67 ywbC 4.4.1.5 E glyoxalase
FLDIGELM_00284 2.7e-219 ywbD 2.1.1.191 J Methyltransferase
FLDIGELM_00285 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
FLDIGELM_00286 1.3e-208 ywbF EGP Major facilitator Superfamily
FLDIGELM_00287 2.3e-111 ywbG M effector of murein hydrolase
FLDIGELM_00288 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
FLDIGELM_00289 5.8e-153 ywbI K Transcriptional regulator
FLDIGELM_00290 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FLDIGELM_00291 2.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
FLDIGELM_00292 3.4e-253 P COG0672 High-affinity Fe2 Pb2 permease
FLDIGELM_00293 2.1e-181 ycdO P periplasmic lipoprotein involved in iron transport
FLDIGELM_00294 3e-221 ywbN P Dyp-type peroxidase family protein
FLDIGELM_00295 1.8e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
FLDIGELM_00296 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLDIGELM_00297 9.8e-49 ywcB S Protein of unknown function, DUF485
FLDIGELM_00299 2.2e-122 ywcC K transcriptional regulator
FLDIGELM_00300 9.5e-60 gtcA S GtrA-like protein
FLDIGELM_00301 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FLDIGELM_00302 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
FLDIGELM_00303 1e-35 ywzA S membrane
FLDIGELM_00304 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
FLDIGELM_00305 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FLDIGELM_00306 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
FLDIGELM_00307 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
FLDIGELM_00308 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
FLDIGELM_00309 2.9e-202 rodA D Belongs to the SEDS family
FLDIGELM_00310 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
FLDIGELM_00311 9.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLDIGELM_00312 0.0 vpr O Belongs to the peptidase S8 family
FLDIGELM_00314 7e-150 sacT K transcriptional antiterminator
FLDIGELM_00315 1.7e-137 focA P Formate/nitrite transporter
FLDIGELM_00316 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FLDIGELM_00317 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
FLDIGELM_00318 2e-28 ywdA
FLDIGELM_00319 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
FLDIGELM_00320 1.3e-57 pex K Transcriptional regulator PadR-like family
FLDIGELM_00321 1.4e-113 ywdD
FLDIGELM_00323 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
FLDIGELM_00324 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FLDIGELM_00325 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
FLDIGELM_00326 7.7e-49 ywdI S Family of unknown function (DUF5327)
FLDIGELM_00327 1.3e-238 ywdJ F Xanthine uracil
FLDIGELM_00328 4.3e-59 ywdK S small membrane protein
FLDIGELM_00329 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
FLDIGELM_00330 2.8e-145 spsA M Spore Coat
FLDIGELM_00331 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
FLDIGELM_00332 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
FLDIGELM_00333 4e-164 spsD 2.3.1.210 K Spore Coat
FLDIGELM_00334 3.2e-214 spsE 2.5.1.56 M acid synthase
FLDIGELM_00335 9.7e-132 spsF M Spore Coat
FLDIGELM_00336 1.7e-190 spsG M Spore Coat
FLDIGELM_00337 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FLDIGELM_00338 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
FLDIGELM_00339 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
FLDIGELM_00340 1.3e-86 spsL 5.1.3.13 M Spore Coat
FLDIGELM_00341 4.4e-77
FLDIGELM_00342 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
FLDIGELM_00343 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
FLDIGELM_00344 0.0 rocB E arginine degradation protein
FLDIGELM_00345 1.4e-259 lysP E amino acid
FLDIGELM_00346 1.7e-205 ywfA EGP Major facilitator Superfamily
FLDIGELM_00347 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
FLDIGELM_00348 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
FLDIGELM_00349 5.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDIGELM_00350 3e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
FLDIGELM_00351 1.6e-208 bacE EGP Major facilitator Superfamily
FLDIGELM_00352 6.6e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
FLDIGELM_00353 1.9e-136 IQ Enoyl-(Acyl carrier protein) reductase
FLDIGELM_00354 3.3e-146 ywfI C May function as heme-dependent peroxidase
FLDIGELM_00355 1.6e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
FLDIGELM_00356 9.2e-164 cysL K Transcriptional regulator
FLDIGELM_00357 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
FLDIGELM_00358 5.7e-158 ywfM EG EamA-like transporter family
FLDIGELM_00359 1e-110 rsfA_1
FLDIGELM_00360 3.1e-36 ywzC S Belongs to the UPF0741 family
FLDIGELM_00361 4.3e-255 ywfO S COG1078 HD superfamily phosphohydrolases
FLDIGELM_00362 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
FLDIGELM_00363 1.5e-77 yffB K Transcriptional regulator
FLDIGELM_00364 2e-237 mmr U Major Facilitator Superfamily
FLDIGELM_00366 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLDIGELM_00367 9.5e-71 ywhA K Transcriptional regulator
FLDIGELM_00368 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
FLDIGELM_00369 3.3e-118 ywhC S Peptidase family M50
FLDIGELM_00370 8.9e-95 ywhD S YwhD family
FLDIGELM_00371 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
FLDIGELM_00372 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FLDIGELM_00373 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
FLDIGELM_00374 1e-84 ywhH S Aminoacyl-tRNA editing domain
FLDIGELM_00376 2.3e-79 S aspartate phosphatase
FLDIGELM_00377 2.5e-205 ywhK CO amine dehydrogenase activity
FLDIGELM_00378 2.9e-249 ywhL CO amine dehydrogenase activity
FLDIGELM_00380 1.2e-249 L Peptidase, M16
FLDIGELM_00381 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
FLDIGELM_00382 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
FLDIGELM_00383 3.3e-132 cbiO V ABC transporter
FLDIGELM_00385 4.9e-270 C Fe-S oxidoreductases
FLDIGELM_00386 1e-07 S Bacteriocin subtilosin A
FLDIGELM_00387 4.7e-73 ywiB S protein conserved in bacteria
FLDIGELM_00388 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
FLDIGELM_00389 2.3e-213 narK P COG2223 Nitrate nitrite transporter
FLDIGELM_00390 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
FLDIGELM_00391 1.7e-139 ywiC S YwiC-like protein
FLDIGELM_00392 4.5e-85 arfM T cyclic nucleotide binding
FLDIGELM_00393 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FLDIGELM_00394 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
FLDIGELM_00395 2.4e-93 narJ 1.7.5.1 C nitrate reductase
FLDIGELM_00396 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
FLDIGELM_00397 1.9e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLDIGELM_00398 0.0 ywjA V ABC transporter
FLDIGELM_00399 4.8e-96 ywjB H RibD C-terminal domain
FLDIGELM_00400 2.7e-42 ywjC
FLDIGELM_00401 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
FLDIGELM_00402 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
FLDIGELM_00403 0.0 fadF C COG0247 Fe-S oxidoreductase
FLDIGELM_00404 1.7e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
FLDIGELM_00405 1.1e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
FLDIGELM_00406 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
FLDIGELM_00407 5.1e-90 ywjG S Domain of unknown function (DUF2529)
FLDIGELM_00408 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
FLDIGELM_00409 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
FLDIGELM_00410 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FLDIGELM_00411 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLDIGELM_00412 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
FLDIGELM_00413 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FLDIGELM_00414 1.1e-32 rpmE J Binds the 23S rRNA
FLDIGELM_00415 2.4e-104 tdk 2.7.1.21 F thymidine kinase
FLDIGELM_00416 0.0 sfcA 1.1.1.38 C malic enzyme
FLDIGELM_00417 8.6e-160 ywkB S Membrane transport protein
FLDIGELM_00418 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
FLDIGELM_00419 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FLDIGELM_00420 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FLDIGELM_00421 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FLDIGELM_00423 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
FLDIGELM_00424 6.1e-112 spoIIR S stage II sporulation protein R
FLDIGELM_00425 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
FLDIGELM_00426 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FLDIGELM_00427 1.7e-91 mntP P Probably functions as a manganese efflux pump
FLDIGELM_00428 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLDIGELM_00429 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
FLDIGELM_00430 7.2e-95 ywlG S Belongs to the UPF0340 family
FLDIGELM_00431 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FLDIGELM_00432 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FLDIGELM_00433 2.5e-62 atpI S ATP synthase
FLDIGELM_00434 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
FLDIGELM_00435 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLDIGELM_00436 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FLDIGELM_00437 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FLDIGELM_00438 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FLDIGELM_00439 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FLDIGELM_00440 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FLDIGELM_00441 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
FLDIGELM_00442 4.3e-88 ywmA
FLDIGELM_00443 1.3e-32 ywzB S membrane
FLDIGELM_00444 1.6e-134 ywmB S TATA-box binding
FLDIGELM_00445 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FLDIGELM_00446 2e-178 spoIID D Stage II sporulation protein D
FLDIGELM_00447 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
FLDIGELM_00448 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
FLDIGELM_00450 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FLDIGELM_00451 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FLDIGELM_00452 1.3e-103 S response regulator aspartate phosphatase
FLDIGELM_00453 3e-84 ywmF S Peptidase M50
FLDIGELM_00454 3.8e-11 csbD K CsbD-like
FLDIGELM_00456 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
FLDIGELM_00457 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
FLDIGELM_00458 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
FLDIGELM_00459 1.7e-64 ywnA K Transcriptional regulator
FLDIGELM_00460 1.6e-114 ywnB S NAD(P)H-binding
FLDIGELM_00461 2.6e-59 ywnC S Family of unknown function (DUF5362)
FLDIGELM_00462 4.1e-144 mta K transcriptional
FLDIGELM_00463 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FLDIGELM_00464 2.2e-70 ywnF S Family of unknown function (DUF5392)
FLDIGELM_00465 2.7e-14 ywnC S Family of unknown function (DUF5362)
FLDIGELM_00466 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
FLDIGELM_00467 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
FLDIGELM_00468 3.5e-73 ywnJ S VanZ like family
FLDIGELM_00469 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
FLDIGELM_00470 1.6e-58 nrgB K Belongs to the P(II) protein family
FLDIGELM_00471 2.5e-225 amt P Ammonium transporter
FLDIGELM_00472 2.2e-76
FLDIGELM_00473 4e-104 phzA Q Isochorismatase family
FLDIGELM_00474 4.4e-242 ywoD EGP Major facilitator superfamily
FLDIGELM_00475 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
FLDIGELM_00476 1.2e-231 ywoF P Right handed beta helix region
FLDIGELM_00477 2.7e-211 ywoG EGP Major facilitator Superfamily
FLDIGELM_00478 2.1e-70 ywoH K COG1846 Transcriptional regulators
FLDIGELM_00479 3e-44 spoIIID K Stage III sporulation protein D
FLDIGELM_00480 3.5e-180 mbl D Rod shape-determining protein
FLDIGELM_00481 6.9e-126 flhO N flagellar basal body
FLDIGELM_00482 1.5e-141 flhP N flagellar basal body
FLDIGELM_00483 2.1e-199 S aspartate phosphatase
FLDIGELM_00484 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FLDIGELM_00485 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
FLDIGELM_00486 1.9e-153 ywpD T Histidine kinase
FLDIGELM_00487 8e-51 srtA 3.4.22.70 M Sortase family
FLDIGELM_00488 1.1e-66 ywpF S YwpF-like protein
FLDIGELM_00489 1.3e-66 ywpG
FLDIGELM_00490 9.8e-58 ssbB L Single-stranded DNA-binding protein
FLDIGELM_00491 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
FLDIGELM_00492 2.3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
FLDIGELM_00493 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
FLDIGELM_00494 3.8e-309 ywqB S SWIM zinc finger
FLDIGELM_00495 1.2e-17
FLDIGELM_00496 2e-116 ywqC M biosynthesis protein
FLDIGELM_00497 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
FLDIGELM_00498 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
FLDIGELM_00499 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLDIGELM_00500 1.3e-153 ywqG S Domain of unknown function (DUF1963)
FLDIGELM_00501 9.7e-23 S Domain of unknown function (DUF5082)
FLDIGELM_00502 3.9e-38 ywqI S Family of unknown function (DUF5344)
FLDIGELM_00503 4.6e-242 ywqJ S Pre-toxin TG
FLDIGELM_00504 1.9e-24
FLDIGELM_00505 1.9e-116 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
FLDIGELM_00506 4.9e-162 K Transcriptional regulator
FLDIGELM_00507 2.2e-99 ywqN S NAD(P)H-dependent
FLDIGELM_00509 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
FLDIGELM_00510 2.4e-104 ywrB P Chromate transporter
FLDIGELM_00511 2.1e-82 ywrC K Transcriptional regulator
FLDIGELM_00512 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
FLDIGELM_00513 2.9e-54 S Domain of unknown function (DUF4181)
FLDIGELM_00514 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FLDIGELM_00515 3.7e-12
FLDIGELM_00516 1.2e-210 cotH M Spore Coat
FLDIGELM_00517 7.6e-131 cotB
FLDIGELM_00518 7.5e-126 ywrJ
FLDIGELM_00519 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FLDIGELM_00520 1.1e-169 alsR K LysR substrate binding domain
FLDIGELM_00521 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
FLDIGELM_00522 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
FLDIGELM_00523 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
FLDIGELM_00524 3.6e-48 ywsA S Protein of unknown function (DUF3892)
FLDIGELM_00525 4.6e-94 batE T Sh3 type 3 domain protein
FLDIGELM_00526 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
FLDIGELM_00527 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
FLDIGELM_00528 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
FLDIGELM_00529 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
FLDIGELM_00530 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FLDIGELM_00531 1.9e-178 rbsR K transcriptional
FLDIGELM_00532 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
FLDIGELM_00533 8.6e-70 pgsC S biosynthesis protein
FLDIGELM_00534 8.2e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
FLDIGELM_00535 3.6e-21 ywtC
FLDIGELM_00536 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
FLDIGELM_00537 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
FLDIGELM_00538 8.4e-171 ywtF K Transcriptional regulator
FLDIGELM_00539 1.9e-248 ywtG EGP Major facilitator Superfamily
FLDIGELM_00540 7.6e-216 gerAC S Spore germination protein
FLDIGELM_00541 7.5e-200 gerBB E Spore germination protein
FLDIGELM_00542 3.5e-266 gerBA EG Spore germination protein
FLDIGELM_00543 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
FLDIGELM_00544 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FLDIGELM_00545 1.2e-260
FLDIGELM_00546 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FLDIGELM_00547 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
FLDIGELM_00548 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
FLDIGELM_00549 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
FLDIGELM_00550 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FLDIGELM_00551 1.1e-150 tagG GM Transport permease protein
FLDIGELM_00552 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
FLDIGELM_00553 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FLDIGELM_00555 8.1e-257 ggaA M Glycosyltransferase like family 2
FLDIGELM_00556 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
FLDIGELM_00557 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FLDIGELM_00558 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
FLDIGELM_00559 9.3e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
FLDIGELM_00560 6e-38
FLDIGELM_00561 0.0 lytB 3.5.1.28 D Stage II sporulation protein
FLDIGELM_00562 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FLDIGELM_00563 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
FLDIGELM_00564 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FLDIGELM_00565 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
FLDIGELM_00566 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLDIGELM_00567 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
FLDIGELM_00568 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
FLDIGELM_00569 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
FLDIGELM_00570 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
FLDIGELM_00571 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
FLDIGELM_00572 6e-163 yvhJ K Transcriptional regulator
FLDIGELM_00573 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
FLDIGELM_00574 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
FLDIGELM_00575 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FLDIGELM_00576 7.3e-155 degV S protein conserved in bacteria
FLDIGELM_00577 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FLDIGELM_00578 5.7e-46 comFB S Late competence development protein ComFB
FLDIGELM_00579 2.7e-129 comFC S Phosphoribosyl transferase domain
FLDIGELM_00580 7e-74 yvyF S flagellar protein
FLDIGELM_00581 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
FLDIGELM_00582 2.4e-78 flgN NOU FlgN protein
FLDIGELM_00583 1.2e-264 flgK N flagellar hook-associated protein
FLDIGELM_00584 1.1e-156 flgL N Belongs to the bacterial flagellin family
FLDIGELM_00585 2.6e-50 yviE
FLDIGELM_00586 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
FLDIGELM_00587 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FLDIGELM_00588 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLDIGELM_00589 6.1e-57 flaG N flagellar protein FlaG
FLDIGELM_00590 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FLDIGELM_00591 2.9e-69 fliS N flagellar protein FliS
FLDIGELM_00592 1.9e-08 fliT S bacterial-type flagellum organization
FLDIGELM_00593 2.8e-66
FLDIGELM_00594 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FLDIGELM_00595 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FLDIGELM_00596 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FLDIGELM_00597 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
FLDIGELM_00598 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
FLDIGELM_00599 1.6e-123 ftsE D cell division ATP-binding protein FtsE
FLDIGELM_00600 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
FLDIGELM_00601 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
FLDIGELM_00602 5.3e-56 swrA S Swarming motility protein
FLDIGELM_00603 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLDIGELM_00604 7.9e-228 yvkA EGP Major facilitator Superfamily
FLDIGELM_00605 7e-101 yvkB K Transcriptional regulator
FLDIGELM_00606 0.0 yvkC 2.7.9.2 GT Phosphotransferase
FLDIGELM_00607 1.2e-30 csbA S protein conserved in bacteria
FLDIGELM_00608 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FLDIGELM_00609 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FLDIGELM_00610 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FLDIGELM_00611 6.7e-34 yvkN
FLDIGELM_00612 8e-49 yvlA
FLDIGELM_00613 3.4e-168 yvlB S Putative adhesin
FLDIGELM_00614 2.6e-26 pspB KT PspC domain
FLDIGELM_00615 1.2e-50 yvlD S Membrane
FLDIGELM_00616 2.7e-203 yvmA EGP Major facilitator Superfamily
FLDIGELM_00617 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
FLDIGELM_00618 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
FLDIGELM_00619 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
FLDIGELM_00620 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
FLDIGELM_00621 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
FLDIGELM_00622 3.6e-134 yvoA K transcriptional
FLDIGELM_00623 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FLDIGELM_00624 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
FLDIGELM_00625 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FLDIGELM_00626 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FLDIGELM_00627 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
FLDIGELM_00628 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
FLDIGELM_00629 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
FLDIGELM_00630 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
FLDIGELM_00631 4.5e-140 yvpB NU protein conserved in bacteria
FLDIGELM_00632 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FLDIGELM_00633 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
FLDIGELM_00634 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FLDIGELM_00635 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
FLDIGELM_00636 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FLDIGELM_00637 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FLDIGELM_00638 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FLDIGELM_00639 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
FLDIGELM_00640 4.6e-121
FLDIGELM_00641 0.0
FLDIGELM_00643 0.0 msbA2 3.6.3.44 V ABC transporter
FLDIGELM_00644 2.4e-278 S COG0457 FOG TPR repeat
FLDIGELM_00645 1.4e-102 usp CBM50 M protein conserved in bacteria
FLDIGELM_00646 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
FLDIGELM_00647 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
FLDIGELM_00648 5.7e-166 rapZ S Displays ATPase and GTPase activities
FLDIGELM_00649 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
FLDIGELM_00650 1.4e-170 whiA K May be required for sporulation
FLDIGELM_00651 1.6e-36 crh G Phosphocarrier protein Chr
FLDIGELM_00652 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
FLDIGELM_00653 1.8e-33
FLDIGELM_00654 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_00655 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
FLDIGELM_00656 5.6e-141 yvcR V ABC transporter, ATP-binding protein
FLDIGELM_00657 0.0 yxdM V ABC transporter (permease)
FLDIGELM_00658 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLDIGELM_00659 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
FLDIGELM_00660 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
FLDIGELM_00661 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
FLDIGELM_00662 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
FLDIGELM_00663 3.6e-174 yvdE K Transcriptional regulator
FLDIGELM_00664 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
FLDIGELM_00665 2e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
FLDIGELM_00666 1e-243 malC P COG1175 ABC-type sugar transport systems, permease components
FLDIGELM_00667 1.5e-147 malD P transport
FLDIGELM_00668 2.9e-154 malA S Protein of unknown function (DUF1189)
FLDIGELM_00669 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
FLDIGELM_00670 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
FLDIGELM_00671 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
FLDIGELM_00672 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FLDIGELM_00674 1.5e-183 S Patatin-like phospholipase
FLDIGELM_00675 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
FLDIGELM_00676 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
FLDIGELM_00677 4.1e-50 sugE P Small Multidrug Resistance protein
FLDIGELM_00678 6.7e-51 ykkC P Small Multidrug Resistance protein
FLDIGELM_00679 7.4e-106 yvdT K Transcriptional regulator
FLDIGELM_00680 1.8e-295 yveA E amino acid
FLDIGELM_00681 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
FLDIGELM_00682 4.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
FLDIGELM_00683 7.4e-97 pbpE V Beta-lactamase
FLDIGELM_00684 3.1e-150 pbpE V Beta-lactamase
FLDIGELM_00685 1.9e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
FLDIGELM_00686 1.7e-73 MA20_18690 S Protein of unknown function (DUF3237)
FLDIGELM_00687 1.7e-92 padC Q Phenolic acid decarboxylase
FLDIGELM_00689 2.5e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
FLDIGELM_00690 6.3e-76 slr K transcriptional
FLDIGELM_00691 4e-122 ywqC M biosynthesis protein
FLDIGELM_00692 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
FLDIGELM_00693 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
FLDIGELM_00694 2e-224 epsD GT4 M Glycosyl transferase 4-like
FLDIGELM_00695 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FLDIGELM_00696 5.3e-220 epsF GT4 M Glycosyl transferases group 1
FLDIGELM_00697 4.8e-207 epsG S EpsG family
FLDIGELM_00698 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
FLDIGELM_00699 3.6e-207 epsI GM pyruvyl transferase
FLDIGELM_00700 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
FLDIGELM_00701 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FLDIGELM_00702 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
FLDIGELM_00703 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
FLDIGELM_00704 2.7e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
FLDIGELM_00705 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
FLDIGELM_00706 1e-31 yvfG S YvfG protein
FLDIGELM_00707 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
FLDIGELM_00708 1.4e-309 yvfH C L-lactate permease
FLDIGELM_00709 1e-112 yvfI K COG2186 Transcriptional regulators
FLDIGELM_00710 1.8e-184 lacR K Transcriptional regulator
FLDIGELM_00711 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
FLDIGELM_00712 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
FLDIGELM_00713 3.2e-150 ganQ P transport
FLDIGELM_00714 0.0 lacA 3.2.1.23 G beta-galactosidase
FLDIGELM_00715 2.6e-252 galA 3.2.1.89 G arabinogalactan
FLDIGELM_00716 1.4e-199 rsbU 3.1.3.3 T response regulator
FLDIGELM_00717 2.6e-157 rsbQ S Alpha/beta hydrolase family
FLDIGELM_00718 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
FLDIGELM_00719 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
FLDIGELM_00720 8.9e-201 desK 2.7.13.3 T Histidine kinase
FLDIGELM_00721 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FLDIGELM_00722 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
FLDIGELM_00723 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
FLDIGELM_00724 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
FLDIGELM_00725 4.3e-197 yvbX S Glycosyl hydrolase
FLDIGELM_00726 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
FLDIGELM_00727 8.5e-157 yvbV EG EamA-like transporter family
FLDIGELM_00728 3.9e-159 yvbU K Transcriptional regulator
FLDIGELM_00729 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLDIGELM_00730 5.5e-203 araR K transcriptional
FLDIGELM_00731 1.6e-252 araE EGP Major facilitator Superfamily
FLDIGELM_00732 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
FLDIGELM_00733 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FLDIGELM_00734 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
FLDIGELM_00735 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FLDIGELM_00736 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
FLDIGELM_00737 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FLDIGELM_00738 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
FLDIGELM_00739 0.0 tcaA S response to antibiotic
FLDIGELM_00740 4.2e-124 exoY M Membrane
FLDIGELM_00741 8.6e-113 yvbH S YvbH-like oligomerisation region
FLDIGELM_00742 6.4e-103 yvbG U UPF0056 membrane protein
FLDIGELM_00743 1.4e-98 yvbF K Belongs to the GbsR family
FLDIGELM_00744 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
FLDIGELM_00745 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
FLDIGELM_00746 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
FLDIGELM_00747 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
FLDIGELM_00748 4.5e-45 sdpR K transcriptional
FLDIGELM_00749 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
FLDIGELM_00750 4.4e-08
FLDIGELM_00751 7.6e-172
FLDIGELM_00752 7.9e-13 S Sporulation delaying protein SdpA
FLDIGELM_00753 8.7e-61 yvbF K Belongs to the GbsR family
FLDIGELM_00754 1.2e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
FLDIGELM_00755 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
FLDIGELM_00756 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
FLDIGELM_00757 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
FLDIGELM_00758 4.2e-226 NT chemotaxis protein
FLDIGELM_00759 2.2e-54 yodB K transcriptional
FLDIGELM_00760 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
FLDIGELM_00761 4e-69 K transcriptional
FLDIGELM_00762 7.5e-36 yvzC K Transcriptional
FLDIGELM_00763 3.7e-153 yvaM S Serine aminopeptidase, S33
FLDIGELM_00764 2.4e-23 secG U Preprotein translocase subunit SecG
FLDIGELM_00765 5.6e-143 est 3.1.1.1 S Carboxylesterase
FLDIGELM_00766 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FLDIGELM_00767 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FLDIGELM_00769 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_00770 4.1e-101 K Bacterial regulatory proteins, tetR family
FLDIGELM_00771 2.8e-55 yvaE P Small Multidrug Resistance protein
FLDIGELM_00772 5.7e-73 yvaD S Family of unknown function (DUF5360)
FLDIGELM_00773 0.0 yvaC S Fusaric acid resistance protein-like
FLDIGELM_00774 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FLDIGELM_00775 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
FLDIGELM_00776 2.2e-48 csoR S transcriptional
FLDIGELM_00777 1.5e-29 copZ P Copper resistance protein CopZ
FLDIGELM_00778 0.0 copA 3.6.3.54 P P-type ATPase
FLDIGELM_00779 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
FLDIGELM_00780 1.6e-104 bdbD O Thioredoxin
FLDIGELM_00781 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
FLDIGELM_00782 4.1e-107 yvgT S membrane
FLDIGELM_00783 0.0 helD 3.6.4.12 L DNA helicase
FLDIGELM_00784 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FLDIGELM_00785 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
FLDIGELM_00786 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
FLDIGELM_00787 5.4e-86 yvgO
FLDIGELM_00788 9.1e-158 yvgN S reductase
FLDIGELM_00789 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
FLDIGELM_00790 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
FLDIGELM_00791 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
FLDIGELM_00792 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FLDIGELM_00793 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
FLDIGELM_00794 6.5e-16 S Small spore protein J (Spore_SspJ)
FLDIGELM_00795 2.6e-237 yvsH E Arginine ornithine antiporter
FLDIGELM_00797 2.1e-179 fhuD P ABC transporter
FLDIGELM_00798 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_00799 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_00800 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
FLDIGELM_00801 4.8e-176 M Efflux transporter rnd family, mfp subunit
FLDIGELM_00802 7.1e-124 macB V ABC transporter, ATP-binding protein
FLDIGELM_00803 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
FLDIGELM_00804 1.3e-64 yvrL S Regulatory protein YrvL
FLDIGELM_00805 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
FLDIGELM_00806 2.4e-19 S YvrJ protein family
FLDIGELM_00807 1.8e-96 yvrI K RNA polymerase
FLDIGELM_00808 3.6e-22
FLDIGELM_00809 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_00810 0.0 T PhoQ Sensor
FLDIGELM_00811 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
FLDIGELM_00812 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_00813 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
FLDIGELM_00814 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_00815 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
FLDIGELM_00816 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
FLDIGELM_00817 4.8e-227 yvqJ EGP Major facilitator Superfamily
FLDIGELM_00818 5.6e-62 liaI S membrane
FLDIGELM_00819 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
FLDIGELM_00820 9.3e-129 liaG S Putative adhesin
FLDIGELM_00821 2.1e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
FLDIGELM_00822 5.5e-187 vraS 2.7.13.3 T Histidine kinase
FLDIGELM_00823 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FLDIGELM_00824 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
FLDIGELM_00825 9.1e-198 gerAB E Spore germination protein
FLDIGELM_00826 3.7e-247 gerAA EG Spore germination protein
FLDIGELM_00827 2.3e-24 S Protein of unknown function (DUF3970)
FLDIGELM_00828 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
FLDIGELM_00829 4.3e-158 yuxN K Transcriptional regulator
FLDIGELM_00830 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
FLDIGELM_00831 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_00832 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLDIGELM_00833 1.2e-79 dps P Ferritin-like domain
FLDIGELM_00834 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_00835 3.2e-301 pepF2 E COG1164 Oligoendopeptidase F
FLDIGELM_00836 5.6e-66 S YusW-like protein
FLDIGELM_00837 1e-153 yusV 3.6.3.34 HP ABC transporter
FLDIGELM_00838 3.8e-47 yusU S Protein of unknown function (DUF2573)
FLDIGELM_00839 2.7e-160 yusT K LysR substrate binding domain
FLDIGELM_00840 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_00841 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_00842 8.4e-66 yusQ S Tautomerase enzyme
FLDIGELM_00843 3.8e-293 yusP P Major facilitator superfamily
FLDIGELM_00844 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
FLDIGELM_00845 3.2e-53 yusN M Coat F domain
FLDIGELM_00846 5.1e-40
FLDIGELM_00847 2.2e-165 fadM E Proline dehydrogenase
FLDIGELM_00848 4.7e-09 S YuzL-like protein
FLDIGELM_00849 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
FLDIGELM_00850 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
FLDIGELM_00851 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
FLDIGELM_00852 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
FLDIGELM_00853 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
FLDIGELM_00854 1.1e-39 yusG S Protein of unknown function (DUF2553)
FLDIGELM_00855 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
FLDIGELM_00856 5.6e-55 traF CO Thioredoxin
FLDIGELM_00857 2.4e-56 yusD S SCP-2 sterol transfer family
FLDIGELM_00858 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FLDIGELM_00859 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
FLDIGELM_00860 3.2e-147 metQ P Belongs to the NlpA lipoprotein family
FLDIGELM_00861 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLDIGELM_00862 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
FLDIGELM_00863 1.4e-245 sufD O assembly protein SufD
FLDIGELM_00864 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FLDIGELM_00865 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
FLDIGELM_00866 3.5e-271 sufB O FeS cluster assembly
FLDIGELM_00867 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FLDIGELM_00868 1e-41
FLDIGELM_00870 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
FLDIGELM_00871 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
FLDIGELM_00872 8.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
FLDIGELM_00873 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
FLDIGELM_00874 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
FLDIGELM_00875 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
FLDIGELM_00876 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
FLDIGELM_00877 1.1e-135 yurK K UTRA
FLDIGELM_00878 1.2e-205 msmX P Belongs to the ABC transporter superfamily
FLDIGELM_00879 2.4e-169 bsn L Ribonuclease
FLDIGELM_00880 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
FLDIGELM_00881 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
FLDIGELM_00883 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FLDIGELM_00884 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
FLDIGELM_00885 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
FLDIGELM_00886 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
FLDIGELM_00887 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
FLDIGELM_00888 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
FLDIGELM_00889 5.2e-281 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
FLDIGELM_00890 4.3e-223 pbuX F xanthine
FLDIGELM_00891 1e-230 pbuX F Permease family
FLDIGELM_00892 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
FLDIGELM_00893 4.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
FLDIGELM_00894 2.8e-60 yunG
FLDIGELM_00895 4.3e-171 yunF S Protein of unknown function DUF72
FLDIGELM_00896 2e-141 yunE S membrane transporter protein
FLDIGELM_00897 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
FLDIGELM_00898 1.1e-47 yunC S Domain of unknown function (DUF1805)
FLDIGELM_00899 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
FLDIGELM_00900 4.5e-196 lytH M Peptidase, M23
FLDIGELM_00901 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FLDIGELM_00902 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FLDIGELM_00903 9.7e-48 yutD S protein conserved in bacteria
FLDIGELM_00904 1e-75 yutE S Protein of unknown function DUF86
FLDIGELM_00905 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
FLDIGELM_00906 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
FLDIGELM_00907 5e-198 yutH S Spore coat protein
FLDIGELM_00908 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
FLDIGELM_00909 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FLDIGELM_00910 1.9e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
FLDIGELM_00911 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
FLDIGELM_00912 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
FLDIGELM_00913 3.5e-57 yuzD S protein conserved in bacteria
FLDIGELM_00914 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
FLDIGELM_00915 3.2e-39 yuzB S Belongs to the UPF0349 family
FLDIGELM_00916 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FLDIGELM_00917 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FLDIGELM_00918 3.7e-63 erpA S Belongs to the HesB IscA family
FLDIGELM_00919 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FLDIGELM_00920 9e-118 paiB K Putative FMN-binding domain
FLDIGELM_00921 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FLDIGELM_00923 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
FLDIGELM_00924 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
FLDIGELM_00925 8.4e-27 yuiB S Putative membrane protein
FLDIGELM_00926 5.6e-118 yuiC S protein conserved in bacteria
FLDIGELM_00927 1.2e-77 yuiD S protein conserved in bacteria
FLDIGELM_00928 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FLDIGELM_00929 3.9e-211 yuiF S antiporter
FLDIGELM_00930 1.1e-93 bioY S Biotin biosynthesis protein
FLDIGELM_00931 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
FLDIGELM_00932 1.3e-167 besA S Putative esterase
FLDIGELM_00933 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_00934 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
FLDIGELM_00935 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
FLDIGELM_00936 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
FLDIGELM_00937 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDIGELM_00938 5e-36 mbtH S MbtH-like protein
FLDIGELM_00939 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
FLDIGELM_00940 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
FLDIGELM_00941 1.5e-228 yukF QT Transcriptional regulator
FLDIGELM_00942 2.8e-45 esxA S Belongs to the WXG100 family
FLDIGELM_00943 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
FLDIGELM_00944 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
FLDIGELM_00945 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
FLDIGELM_00946 0.0 esaA S type VII secretion protein EsaA
FLDIGELM_00947 7.3e-64 yueC S Family of unknown function (DUF5383)
FLDIGELM_00948 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDIGELM_00949 4.8e-96 yueE S phosphohydrolase
FLDIGELM_00950 2.9e-24 S Protein of unknown function (DUF2642)
FLDIGELM_00951 3.5e-67 S Protein of unknown function (DUF2283)
FLDIGELM_00952 3.2e-190 yueF S transporter activity
FLDIGELM_00953 1.7e-31 yueG S Spore germination protein gerPA/gerPF
FLDIGELM_00954 7.4e-39 yueH S YueH-like protein
FLDIGELM_00955 4.6e-67 yueI S Protein of unknown function (DUF1694)
FLDIGELM_00956 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
FLDIGELM_00957 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FLDIGELM_00958 3.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
FLDIGELM_00959 1.1e-22 yuzC
FLDIGELM_00961 3e-141 comQ H Belongs to the FPP GGPP synthase family
FLDIGELM_00963 2.4e-269 comP 2.7.13.3 T Histidine kinase
FLDIGELM_00964 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FLDIGELM_00965 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
FLDIGELM_00966 2.2e-58 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
FLDIGELM_00967 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FLDIGELM_00968 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FLDIGELM_00969 1.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FLDIGELM_00970 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FLDIGELM_00971 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
FLDIGELM_00972 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
FLDIGELM_00973 1.9e-14
FLDIGELM_00974 1.3e-233 maeN C COG3493 Na citrate symporter
FLDIGELM_00975 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
FLDIGELM_00976 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
FLDIGELM_00977 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
FLDIGELM_00978 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
FLDIGELM_00979 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
FLDIGELM_00980 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
FLDIGELM_00981 6.3e-78 yufK S Family of unknown function (DUF5366)
FLDIGELM_00982 6.3e-75 yuxK S protein conserved in bacteria
FLDIGELM_00983 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
FLDIGELM_00984 3.5e-186 yuxJ EGP Major facilitator Superfamily
FLDIGELM_00986 1.9e-115 kapD L the KinA pathway to sporulation
FLDIGELM_00987 2e-70 kapB G Kinase associated protein B
FLDIGELM_00988 4.6e-233 T PhoQ Sensor
FLDIGELM_00989 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
FLDIGELM_00990 9.8e-42 yugE S Domain of unknown function (DUF1871)
FLDIGELM_00991 1e-156 yugF I Hydrolase
FLDIGELM_00992 1.6e-85 alaR K Transcriptional regulator
FLDIGELM_00993 2.1e-199 yugH 2.6.1.1 E Aminotransferase
FLDIGELM_00994 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
FLDIGELM_00995 1.1e-34 yuzA S Domain of unknown function (DUF378)
FLDIGELM_00996 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
FLDIGELM_00997 2.8e-229 yugK C Dehydrogenase
FLDIGELM_00998 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
FLDIGELM_01000 1.3e-72 yugN S YugN-like family
FLDIGELM_01001 2.2e-182 yugO P COG1226 Kef-type K transport systems
FLDIGELM_01002 1.1e-53 mstX S Membrane-integrating protein Mistic
FLDIGELM_01003 3.7e-36
FLDIGELM_01004 1.4e-116 yugP S Zn-dependent protease
FLDIGELM_01005 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
FLDIGELM_01006 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
FLDIGELM_01007 2.1e-72 yugU S Uncharacterised protein family UPF0047
FLDIGELM_01008 2.3e-35
FLDIGELM_01009 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
FLDIGELM_01010 9.3e-225 mcpA NT chemotaxis protein
FLDIGELM_01011 6.9e-220 mcpA NT chemotaxis protein
FLDIGELM_01012 8.5e-295 mcpA NT chemotaxis protein
FLDIGELM_01013 2.1e-237 mcpA NT chemotaxis protein
FLDIGELM_01015 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
FLDIGELM_01016 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
FLDIGELM_01017 1.8e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
FLDIGELM_01018 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
FLDIGELM_01019 7.5e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
FLDIGELM_01020 3.3e-183 ygjR S Oxidoreductase
FLDIGELM_01021 1.3e-194 yubA S transporter activity
FLDIGELM_01022 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
FLDIGELM_01024 6.4e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
FLDIGELM_01025 4.9e-274 yubD P Major Facilitator Superfamily
FLDIGELM_01026 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FLDIGELM_01027 1e-38 yiaA S yiaA/B two helix domain
FLDIGELM_01028 1.6e-236 ktrB P Potassium
FLDIGELM_01029 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
FLDIGELM_01030 2.2e-91 yuaB
FLDIGELM_01031 2.7e-94 yuaC K Belongs to the GbsR family
FLDIGELM_01032 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
FLDIGELM_01033 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
FLDIGELM_01034 3.9e-107 yuaD
FLDIGELM_01035 3.9e-84 yuaE S DinB superfamily
FLDIGELM_01036 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
FLDIGELM_01037 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
FLDIGELM_01038 3.4e-94 M1-753 M FR47-like protein
FLDIGELM_01039 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
FLDIGELM_01044 2e-08
FLDIGELM_01051 1.3e-09
FLDIGELM_01052 7.8e-08
FLDIGELM_01061 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FLDIGELM_01062 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FLDIGELM_01063 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
FLDIGELM_01064 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
FLDIGELM_01065 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
FLDIGELM_01066 9.9e-77 tspO T membrane
FLDIGELM_01067 1.8e-206 cotI S Spore coat protein
FLDIGELM_01068 1.8e-217 cotSA M Glycosyl transferases group 1
FLDIGELM_01069 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
FLDIGELM_01071 3.6e-235 ytcC M Glycosyltransferase Family 4
FLDIGELM_01072 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
FLDIGELM_01073 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
FLDIGELM_01074 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
FLDIGELM_01075 2.6e-132 dksA T COG1734 DnaK suppressor protein
FLDIGELM_01076 3.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
FLDIGELM_01077 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FLDIGELM_01078 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
FLDIGELM_01079 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FLDIGELM_01080 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
FLDIGELM_01081 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
FLDIGELM_01082 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
FLDIGELM_01083 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
FLDIGELM_01084 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
FLDIGELM_01085 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
FLDIGELM_01086 1.1e-24 S Domain of Unknown Function (DUF1540)
FLDIGELM_01087 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
FLDIGELM_01088 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
FLDIGELM_01089 3.6e-41 rpmE2 J Ribosomal protein L31
FLDIGELM_01090 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
FLDIGELM_01091 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FLDIGELM_01092 3.6e-73 ytkA S YtkA-like
FLDIGELM_01094 2.1e-76 dps P Belongs to the Dps family
FLDIGELM_01095 5.4e-63 ytkC S Bacteriophage holin family
FLDIGELM_01096 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
FLDIGELM_01097 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
FLDIGELM_01098 1.4e-144 ytlC P ABC transporter
FLDIGELM_01099 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
FLDIGELM_01100 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
FLDIGELM_01101 1.2e-38 ytmB S Protein of unknown function (DUF2584)
FLDIGELM_01102 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FLDIGELM_01103 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FLDIGELM_01104 0.0 asnB 6.3.5.4 E Asparagine synthase
FLDIGELM_01105 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
FLDIGELM_01106 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FLDIGELM_01107 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
FLDIGELM_01108 2.8e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
FLDIGELM_01109 2.2e-105 ytqB J Putative rRNA methylase
FLDIGELM_01110 8.1e-190 yhcC S Fe-S oxidoreductase
FLDIGELM_01111 6.7e-41 ytzC S Protein of unknown function (DUF2524)
FLDIGELM_01113 5.1e-66 ytrA K GntR family transcriptional regulator
FLDIGELM_01114 4.2e-161 ytrB P abc transporter atp-binding protein
FLDIGELM_01115 8.3e-150 P ABC-2 family transporter protein
FLDIGELM_01116 2e-140
FLDIGELM_01117 3.1e-127 ytrE V ABC transporter, ATP-binding protein
FLDIGELM_01118 5.5e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
FLDIGELM_01119 2.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_01120 1.6e-185 T PhoQ Sensor
FLDIGELM_01121 1.1e-138 bceA V ABC transporter, ATP-binding protein
FLDIGELM_01122 0.0 bceB V ABC transporter (permease)
FLDIGELM_01123 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
FLDIGELM_01124 2.1e-211 yttB EGP Major facilitator Superfamily
FLDIGELM_01125 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
FLDIGELM_01126 7.7e-55 ytvB S Protein of unknown function (DUF4257)
FLDIGELM_01127 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
FLDIGELM_01128 2.1e-51 ytwF P Sulfurtransferase
FLDIGELM_01129 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
FLDIGELM_01130 3.1e-142 amyC P ABC transporter (permease)
FLDIGELM_01131 1.4e-167 amyD P ABC transporter
FLDIGELM_01132 1.2e-246 msmE G Bacterial extracellular solute-binding protein
FLDIGELM_01133 1.9e-189 msmR K Transcriptional regulator
FLDIGELM_01134 4.8e-145 ytaP S Acetyl xylan esterase (AXE1)
FLDIGELM_01135 3.3e-149 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
FLDIGELM_01136 3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
FLDIGELM_01137 1.8e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
FLDIGELM_01138 1.6e-123 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FLDIGELM_01139 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FLDIGELM_01140 2.7e-224 bioI 1.14.14.46 C Cytochrome P450
FLDIGELM_01141 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
FLDIGELM_01142 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
FLDIGELM_01143 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
FLDIGELM_01144 0.0 ytdP K Transcriptional regulator
FLDIGELM_01145 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
FLDIGELM_01146 1e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
FLDIGELM_01147 5.1e-72 yteS G transport
FLDIGELM_01148 6.6e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
FLDIGELM_01149 4.8e-117 yteU S Integral membrane protein
FLDIGELM_01150 3.1e-26 yteV S Sporulation protein Cse60
FLDIGELM_01151 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
FLDIGELM_01152 8.2e-232 ytfP S HI0933-like protein
FLDIGELM_01153 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FLDIGELM_01154 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FLDIGELM_01155 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
FLDIGELM_01156 4.8e-131 ythP V ABC transporter
FLDIGELM_01157 4.6e-200 ythQ U Bacterial ABC transporter protein EcsB
FLDIGELM_01158 2.1e-225 pbuO S permease
FLDIGELM_01159 2.3e-270 pepV 3.5.1.18 E Dipeptidase
FLDIGELM_01160 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FLDIGELM_01161 2.6e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FLDIGELM_01162 1.3e-165 ytlQ
FLDIGELM_01163 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
FLDIGELM_01164 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
FLDIGELM_01165 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
FLDIGELM_01166 2e-45 ytzH S YtzH-like protein
FLDIGELM_01167 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
FLDIGELM_01168 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
FLDIGELM_01169 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
FLDIGELM_01170 9.8e-52 ytzB S small secreted protein
FLDIGELM_01171 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
FLDIGELM_01172 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
FLDIGELM_01173 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
FLDIGELM_01174 9.8e-149 ytpQ S Belongs to the UPF0354 family
FLDIGELM_01175 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FLDIGELM_01176 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
FLDIGELM_01177 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
FLDIGELM_01178 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FLDIGELM_01179 6.6e-17 ytxH S COG4980 Gas vesicle protein
FLDIGELM_01180 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
FLDIGELM_01181 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
FLDIGELM_01182 1.7e-182 ccpA K catabolite control protein A
FLDIGELM_01183 7.1e-147 motA N flagellar motor
FLDIGELM_01184 1.4e-125 motS N Flagellar motor protein
FLDIGELM_01185 1.9e-225 acuC BQ histone deacetylase
FLDIGELM_01186 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
FLDIGELM_01187 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
FLDIGELM_01188 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
FLDIGELM_01189 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FLDIGELM_01191 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FLDIGELM_01192 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
FLDIGELM_01193 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
FLDIGELM_01194 3.4e-109 yttP K Transcriptional regulator
FLDIGELM_01195 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
FLDIGELM_01196 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FLDIGELM_01197 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
FLDIGELM_01198 1.2e-208 iscS2 2.8.1.7 E Cysteine desulfurase
FLDIGELM_01199 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FLDIGELM_01200 2e-29 sspB S spore protein
FLDIGELM_01201 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
FLDIGELM_01202 0.0 ytcJ S amidohydrolase
FLDIGELM_01203 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLDIGELM_01204 2.4e-181 sppA OU signal peptide peptidase SppA
FLDIGELM_01205 1.3e-87 yteJ S RDD family
FLDIGELM_01206 5.6e-116 ytfI S Protein of unknown function (DUF2953)
FLDIGELM_01207 8.7e-70 ytfJ S Sporulation protein YtfJ
FLDIGELM_01208 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FLDIGELM_01209 7e-165 ytxK 2.1.1.72 L DNA methylase
FLDIGELM_01210 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FLDIGELM_01211 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
FLDIGELM_01212 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
FLDIGELM_01213 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
FLDIGELM_01215 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDIGELM_01216 1.7e-130 ytkL S Belongs to the UPF0173 family
FLDIGELM_01217 2.9e-173 ytlI K LysR substrate binding domain
FLDIGELM_01218 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
FLDIGELM_01219 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
FLDIGELM_01220 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
FLDIGELM_01221 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
FLDIGELM_01222 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
FLDIGELM_01223 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FLDIGELM_01224 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLDIGELM_01225 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
FLDIGELM_01226 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLDIGELM_01227 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
FLDIGELM_01228 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
FLDIGELM_01229 1.2e-158 ytnM S membrane transporter protein
FLDIGELM_01230 8e-241 ytoI K transcriptional regulator containing CBS domains
FLDIGELM_01231 2.4e-47 ytpI S YtpI-like protein
FLDIGELM_01232 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
FLDIGELM_01233 9.2e-29
FLDIGELM_01234 8.2e-69 ytrI
FLDIGELM_01235 3.2e-56 ytrH S Sporulation protein YtrH
FLDIGELM_01236 0.0 dnaE 2.7.7.7 L DNA polymerase
FLDIGELM_01237 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
FLDIGELM_01238 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FLDIGELM_01239 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
FLDIGELM_01240 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
FLDIGELM_01241 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
FLDIGELM_01242 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
FLDIGELM_01243 2.6e-192 ytvI S sporulation integral membrane protein YtvI
FLDIGELM_01244 4.7e-71 yeaL S membrane
FLDIGELM_01245 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
FLDIGELM_01246 1.8e-242 icd 1.1.1.42 C isocitrate
FLDIGELM_01247 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
FLDIGELM_01248 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_01249 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
FLDIGELM_01250 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FLDIGELM_01251 7.8e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
FLDIGELM_01252 1.1e-107 ytaF P Probably functions as a manganese efflux pump
FLDIGELM_01253 5.4e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FLDIGELM_01254 8.9e-161 ytbE S reductase
FLDIGELM_01255 2.1e-200 ytbD EGP Major facilitator Superfamily
FLDIGELM_01256 9.9e-67 ytcD K Transcriptional regulator
FLDIGELM_01257 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FLDIGELM_01258 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FLDIGELM_01259 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FLDIGELM_01260 1.5e-264 dnaB L Membrane attachment protein
FLDIGELM_01261 3e-173 dnaI L Primosomal protein DnaI
FLDIGELM_01262 4.9e-111 ytxB S SNARE associated Golgi protein
FLDIGELM_01263 1e-156 ytxC S YtxC-like family
FLDIGELM_01265 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FLDIGELM_01266 1.5e-149 ysaA S HAD-hyrolase-like
FLDIGELM_01267 0.0 lytS 2.7.13.3 T Histidine kinase
FLDIGELM_01268 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
FLDIGELM_01269 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
FLDIGELM_01270 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
FLDIGELM_01272 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FLDIGELM_01273 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
FLDIGELM_01274 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FLDIGELM_01275 7.5e-45 ysdA S Membrane
FLDIGELM_01276 9.2e-68 ysdB S Sigma-w pathway protein YsdB
FLDIGELM_01277 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
FLDIGELM_01278 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
FLDIGELM_01279 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
FLDIGELM_01280 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
FLDIGELM_01281 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
FLDIGELM_01282 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
FLDIGELM_01283 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
FLDIGELM_01284 2.8e-254 araN G carbohydrate transport
FLDIGELM_01285 1.4e-167 araP G carbohydrate transport
FLDIGELM_01286 3.4e-144 araQ G transport system permease
FLDIGELM_01287 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
FLDIGELM_01288 0.0 cstA T Carbon starvation protein
FLDIGELM_01290 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
FLDIGELM_01291 5.6e-258 glcF C Glycolate oxidase
FLDIGELM_01292 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
FLDIGELM_01293 4.4e-208 ysfB KT regulator
FLDIGELM_01294 2.6e-32 sspI S Belongs to the SspI family
FLDIGELM_01295 5.9e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLDIGELM_01296 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FLDIGELM_01297 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FLDIGELM_01298 2e-169 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLDIGELM_01299 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FLDIGELM_01300 1.3e-85 cvpA S membrane protein, required for colicin V production
FLDIGELM_01301 0.0 polX L COG1796 DNA polymerase IV (family X)
FLDIGELM_01302 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FLDIGELM_01303 7.3e-68 yshE S membrane
FLDIGELM_01304 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
FLDIGELM_01305 2.7e-100 fadR K Transcriptional regulator
FLDIGELM_01306 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
FLDIGELM_01307 4.5e-135 etfB C Electron transfer flavoprotein
FLDIGELM_01308 2.1e-177 etfA C Electron transfer flavoprotein
FLDIGELM_01310 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
FLDIGELM_01311 2e-52 trxA O Belongs to the thioredoxin family
FLDIGELM_01312 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FLDIGELM_01313 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
FLDIGELM_01314 1.2e-79 yslB S Protein of unknown function (DUF2507)
FLDIGELM_01315 2.4e-107 sdhC C succinate dehydrogenase
FLDIGELM_01316 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
FLDIGELM_01317 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
FLDIGELM_01318 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
FLDIGELM_01319 3.3e-30 gerE K Transcriptional regulator
FLDIGELM_01320 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
FLDIGELM_01321 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
FLDIGELM_01322 2.9e-196 gerM S COG5401 Spore germination protein
FLDIGELM_01323 9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FLDIGELM_01324 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FLDIGELM_01325 1.4e-92 ysnB S Phosphoesterase
FLDIGELM_01327 9.1e-134 ysnF S protein conserved in bacteria
FLDIGELM_01328 7.6e-82 ysnE K acetyltransferase
FLDIGELM_01330 0.0 ilvB 2.2.1.6 E Acetolactate synthase
FLDIGELM_01331 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
FLDIGELM_01332 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FLDIGELM_01333 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FLDIGELM_01334 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
FLDIGELM_01335 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FLDIGELM_01336 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FLDIGELM_01337 2.3e-187 ysoA H Tetratricopeptide repeat
FLDIGELM_01338 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FLDIGELM_01339 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FLDIGELM_01340 6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
FLDIGELM_01341 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FLDIGELM_01342 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
FLDIGELM_01343 1.4e-89 ysxD
FLDIGELM_01344 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FLDIGELM_01345 3.6e-146 hemX O cytochrome C
FLDIGELM_01346 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
FLDIGELM_01347 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
FLDIGELM_01348 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
FLDIGELM_01349 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
FLDIGELM_01350 1.9e-226 spoVID M stage VI sporulation protein D
FLDIGELM_01351 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FLDIGELM_01352 1.6e-25
FLDIGELM_01353 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FLDIGELM_01354 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
FLDIGELM_01355 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
FLDIGELM_01356 1.1e-168 spoIIB S Sporulation related domain
FLDIGELM_01357 2.8e-102 maf D septum formation protein Maf
FLDIGELM_01358 5.9e-126 radC E Belongs to the UPF0758 family
FLDIGELM_01359 1.8e-184 mreB D Rod shape-determining protein MreB
FLDIGELM_01360 2.8e-157 mreC M Involved in formation and maintenance of cell shape
FLDIGELM_01361 1.4e-84 mreD M shape-determining protein
FLDIGELM_01362 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
FLDIGELM_01363 2.5e-144 minD D Belongs to the ParA family
FLDIGELM_01364 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
FLDIGELM_01365 9.2e-161 spoIVFB S Stage IV sporulation protein
FLDIGELM_01366 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
FLDIGELM_01367 4.1e-56 ysxB J ribosomal protein
FLDIGELM_01368 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
FLDIGELM_01369 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
FLDIGELM_01370 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FLDIGELM_01371 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
FLDIGELM_01372 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
FLDIGELM_01373 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
FLDIGELM_01374 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
FLDIGELM_01375 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
FLDIGELM_01376 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
FLDIGELM_01377 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FLDIGELM_01378 9.8e-158 safA M spore coat assembly protein SafA
FLDIGELM_01379 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FLDIGELM_01380 1.9e-127 yebC K transcriptional regulatory protein
FLDIGELM_01381 1.8e-262 alsT E Sodium alanine symporter
FLDIGELM_01382 2.6e-35 S Family of unknown function (DUF5412)
FLDIGELM_01384 6.5e-119 yrzF T serine threonine protein kinase
FLDIGELM_01385 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
FLDIGELM_01386 5.3e-253 csbX EGP Major facilitator Superfamily
FLDIGELM_01387 4.8e-93 bofC S BofC C-terminal domain
FLDIGELM_01388 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
FLDIGELM_01389 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
FLDIGELM_01390 2.6e-18 yrzS S Protein of unknown function (DUF2905)
FLDIGELM_01391 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FLDIGELM_01392 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
FLDIGELM_01393 1.1e-38 yajC U Preprotein translocase subunit YajC
FLDIGELM_01394 1.2e-74 yrzE S Protein of unknown function (DUF3792)
FLDIGELM_01395 2.2e-114 yrbG S membrane
FLDIGELM_01396 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FLDIGELM_01397 9.4e-49 yrzD S Post-transcriptional regulator
FLDIGELM_01398 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FLDIGELM_01399 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
FLDIGELM_01400 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
FLDIGELM_01401 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
FLDIGELM_01402 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FLDIGELM_01403 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FLDIGELM_01404 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FLDIGELM_01405 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
FLDIGELM_01407 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
FLDIGELM_01408 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FLDIGELM_01409 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
FLDIGELM_01410 4.8e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
FLDIGELM_01411 1.2e-70 cymR K Transcriptional regulator
FLDIGELM_01412 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
FLDIGELM_01413 5.6e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FLDIGELM_01414 5.1e-15 S COG0457 FOG TPR repeat
FLDIGELM_01415 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
FLDIGELM_01416 3e-81 yrrD S protein conserved in bacteria
FLDIGELM_01417 9.8e-31 yrzR
FLDIGELM_01418 8e-08 S Protein of unknown function (DUF3918)
FLDIGELM_01419 7.6e-107 glnP P ABC transporter
FLDIGELM_01420 3.6e-109 gluC P ABC transporter
FLDIGELM_01421 1.9e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
FLDIGELM_01422 8.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FLDIGELM_01423 4.1e-163 yrrI S AI-2E family transporter
FLDIGELM_01424 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FLDIGELM_01425 1.7e-41 yrzL S Belongs to the UPF0297 family
FLDIGELM_01426 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FLDIGELM_01427 1.2e-45 yrzB S Belongs to the UPF0473 family
FLDIGELM_01428 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FLDIGELM_01429 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
FLDIGELM_01430 7.8e-174 yegQ O Peptidase U32
FLDIGELM_01431 2.7e-246 yegQ O COG0826 Collagenase and related proteases
FLDIGELM_01432 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
FLDIGELM_01433 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FLDIGELM_01434 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
FLDIGELM_01435 4.2e-63 yrrS S Protein of unknown function (DUF1510)
FLDIGELM_01436 3.5e-26 yrzA S Protein of unknown function (DUF2536)
FLDIGELM_01437 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
FLDIGELM_01438 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FLDIGELM_01439 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
FLDIGELM_01440 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FLDIGELM_01441 4.6e-35 yrhC S YrhC-like protein
FLDIGELM_01442 1.4e-78 yrhD S Protein of unknown function (DUF1641)
FLDIGELM_01443 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
FLDIGELM_01444 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
FLDIGELM_01445 1.8e-142 focA P Formate nitrite
FLDIGELM_01448 4.5e-97 yrhH Q methyltransferase
FLDIGELM_01449 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
FLDIGELM_01450 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
FLDIGELM_01451 3.3e-46 yrhK S YrhK-like protein
FLDIGELM_01452 0.0 yrhL I Acyltransferase family
FLDIGELM_01453 3.8e-151 rsiV S Protein of unknown function (DUF3298)
FLDIGELM_01454 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
FLDIGELM_01455 2e-149 yrhO K Archaeal transcriptional regulator TrmB
FLDIGELM_01456 3.6e-106 yrhP E LysE type translocator
FLDIGELM_01457 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
FLDIGELM_01458 0.0 levR K PTS system fructose IIA component
FLDIGELM_01459 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
FLDIGELM_01460 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
FLDIGELM_01461 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
FLDIGELM_01462 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
FLDIGELM_01463 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
FLDIGELM_01464 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
FLDIGELM_01465 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
FLDIGELM_01466 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
FLDIGELM_01467 4.3e-47 yraB K helix_turn_helix, mercury resistance
FLDIGELM_01468 1.1e-49 yraD M Spore coat protein
FLDIGELM_01469 2.6e-26 yraE
FLDIGELM_01470 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
FLDIGELM_01471 6.4e-63 yraF M Spore coat protein
FLDIGELM_01472 5.3e-37 yraG
FLDIGELM_01473 1.3e-66 E Glyoxalase-like domain
FLDIGELM_01474 2.4e-61 T sh3 domain protein
FLDIGELM_01475 1.7e-60 T sh3 domain protein
FLDIGELM_01476 3.2e-155 S Alpha beta hydrolase
FLDIGELM_01477 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FLDIGELM_01478 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
FLDIGELM_01480 1.6e-205 yraM S PrpF protein
FLDIGELM_01481 3.4e-163 yraN K Transcriptional regulator
FLDIGELM_01482 9.5e-226 yraO C Citrate transporter
FLDIGELM_01483 4.5e-188 yrpG C Aldo/keto reductase family
FLDIGELM_01484 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
FLDIGELM_01485 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
FLDIGELM_01487 3e-125 yrpD S Domain of unknown function, YrpD
FLDIGELM_01488 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
FLDIGELM_01489 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
FLDIGELM_01490 7.6e-168 aadK G Streptomycin adenylyltransferase
FLDIGELM_01491 1.2e-91 yrdA S DinB family
FLDIGELM_01492 1.9e-57 S Protein of unknown function (DUF2568)
FLDIGELM_01493 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
FLDIGELM_01494 4.1e-231 cypA C Cytochrome P450
FLDIGELM_01495 4.1e-46 yrdF K ribonuclease inhibitor
FLDIGELM_01496 2.2e-79 bkdR K helix_turn_helix ASNC type
FLDIGELM_01497 2.8e-137 azlC E AzlC protein
FLDIGELM_01498 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
FLDIGELM_01499 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
FLDIGELM_01501 2.5e-161 gltR K LysR substrate binding domain
FLDIGELM_01502 1.3e-66 yodA S tautomerase
FLDIGELM_01503 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
FLDIGELM_01504 2e-199 trkA P Oxidoreductase
FLDIGELM_01505 3.9e-159 yrdQ K Transcriptional regulator
FLDIGELM_01506 1.7e-171 yrdR EG EamA-like transporter family
FLDIGELM_01507 2.1e-17 S YrzO-like protein
FLDIGELM_01508 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
FLDIGELM_01509 7.5e-75 bltD 2.3.1.57 K FR47-like protein
FLDIGELM_01510 3.5e-211 blt EGP Major facilitator Superfamily
FLDIGELM_01511 4.8e-151 bltR K helix_turn_helix, mercury resistance
FLDIGELM_01512 2.6e-108 yrkC G Cupin domain
FLDIGELM_01513 7.8e-39 yrkD S protein conserved in bacteria
FLDIGELM_01514 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
FLDIGELM_01515 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
FLDIGELM_01516 2.3e-212 yrkH P Rhodanese Homology Domain
FLDIGELM_01517 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
FLDIGELM_01518 4.3e-117 yrkJ S membrane transporter protein
FLDIGELM_01519 2.8e-79 S Protein of unknown function with HXXEE motif
FLDIGELM_01520 1.5e-97 ywrO S Flavodoxin-like fold
FLDIGELM_01521 6e-105 yrkN K Acetyltransferase (GNAT) family
FLDIGELM_01522 8.2e-224 yrkO P Protein of unknown function (DUF418)
FLDIGELM_01523 1.1e-127 T Transcriptional regulator
FLDIGELM_01524 9e-237 yrkQ T Histidine kinase
FLDIGELM_01525 2e-68 psiE S Protein PsiE homolog
FLDIGELM_01526 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLDIGELM_01527 1.4e-100 yqaB E IrrE N-terminal-like domain
FLDIGELM_01528 1e-101 adk 2.7.4.3 F adenylate kinase activity
FLDIGELM_01530 1.1e-56 K sequence-specific DNA binding
FLDIGELM_01531 6.5e-37 K Helix-turn-helix XRE-family like proteins
FLDIGELM_01533 1.2e-103
FLDIGELM_01537 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
FLDIGELM_01538 2.5e-155 recT L RecT family
FLDIGELM_01539 1e-122 3.1.3.16 L DnaD domain protein
FLDIGELM_01540 5.9e-168 xkdC L IstB-like ATP binding protein
FLDIGELM_01542 7.2e-74 rusA L Endodeoxyribonuclease RusA
FLDIGELM_01543 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
FLDIGELM_01544 1.6e-166
FLDIGELM_01545 6.5e-81 L Transposase
FLDIGELM_01547 6.3e-107 yqaS L DNA packaging
FLDIGELM_01548 2.4e-253 S phage terminase, large subunit
FLDIGELM_01549 5.9e-296 yqbA S portal protein
FLDIGELM_01550 5.7e-169 S Phage Mu protein F like protein
FLDIGELM_01551 2e-115
FLDIGELM_01552 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
FLDIGELM_01553 1.9e-167 xkdG S Phage capsid family
FLDIGELM_01554 3.6e-51 S YqbF, hypothetical protein domain
FLDIGELM_01555 2.1e-67 S Protein of unknown function (DUF3199)
FLDIGELM_01556 6.7e-65 yqbH S Domain of unknown function (DUF3599)
FLDIGELM_01557 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
FLDIGELM_01558 1.4e-77
FLDIGELM_01559 3.2e-26
FLDIGELM_01560 5.5e-256 xkdK S Phage tail sheath C-terminal domain
FLDIGELM_01561 3.6e-76 xkdM S Phage tail tube protein
FLDIGELM_01563 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
FLDIGELM_01564 0.0 xkdO L Transglycosylase SLT domain
FLDIGELM_01565 9e-114 xkdP S Lysin motif
FLDIGELM_01566 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
FLDIGELM_01567 1.8e-38 xkdR S Protein of unknown function (DUF2577)
FLDIGELM_01568 9.6e-71 xkdS S Protein of unknown function (DUF2634)
FLDIGELM_01569 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
FLDIGELM_01570 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
FLDIGELM_01571 9.6e-40
FLDIGELM_01572 2e-221
FLDIGELM_01573 4.1e-56 xkdW S XkdW protein
FLDIGELM_01574 1.3e-23
FLDIGELM_01575 4.8e-165 xepA
FLDIGELM_01576 2.6e-68 S Bacteriophage holin family
FLDIGELM_01577 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
FLDIGELM_01579 5e-60
FLDIGELM_01581 1.1e-104 S Suppressor of fused protein (SUFU)
FLDIGELM_01582 3.8e-277 A Pre-toxin TG
FLDIGELM_01585 1.6e-96 S Tetratricopeptide repeat
FLDIGELM_01586 1.1e-152 yqcI S YqcI/YcgG family
FLDIGELM_01587 1.6e-54 arsR K ArsR family transcriptional regulator
FLDIGELM_01588 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FLDIGELM_01589 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
FLDIGELM_01590 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
FLDIGELM_01591 1.4e-281 cisA2 L Recombinase
FLDIGELM_01592 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLDIGELM_01593 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
FLDIGELM_01594 2.3e-133 yqeB
FLDIGELM_01595 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
FLDIGELM_01596 4.7e-106 yqeD S SNARE associated Golgi protein
FLDIGELM_01597 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FLDIGELM_01598 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
FLDIGELM_01600 5.3e-95 yqeG S hydrolase of the HAD superfamily
FLDIGELM_01601 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
FLDIGELM_01602 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FLDIGELM_01603 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
FLDIGELM_01604 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FLDIGELM_01605 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
FLDIGELM_01606 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FLDIGELM_01607 2.9e-139 yqeM Q Methyltransferase
FLDIGELM_01608 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLDIGELM_01609 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
FLDIGELM_01610 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
FLDIGELM_01611 0.0 comEC S Competence protein ComEC
FLDIGELM_01612 4.1e-15 S YqzM-like protein
FLDIGELM_01613 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
FLDIGELM_01614 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
FLDIGELM_01615 6.6e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FLDIGELM_01616 6.9e-223 spoIIP M stage II sporulation protein P
FLDIGELM_01617 1e-54 yqxA S Protein of unknown function (DUF3679)
FLDIGELM_01618 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FLDIGELM_01619 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
FLDIGELM_01620 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
FLDIGELM_01621 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FLDIGELM_01622 0.0 dnaK O Heat shock 70 kDa protein
FLDIGELM_01623 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FLDIGELM_01624 5.4e-175 prmA J Methylates ribosomal protein L11
FLDIGELM_01625 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
FLDIGELM_01626 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
FLDIGELM_01627 1.6e-158 yqeW P COG1283 Na phosphate symporter
FLDIGELM_01628 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
FLDIGELM_01629 2.5e-61 yqeY S Yqey-like protein
FLDIGELM_01630 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
FLDIGELM_01631 4.3e-122 yqfA S UPF0365 protein
FLDIGELM_01632 6e-25 yqfB
FLDIGELM_01633 2.7e-45 yqfC S sporulation protein YqfC
FLDIGELM_01634 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
FLDIGELM_01635 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
FLDIGELM_01637 0.0 yqfF S membrane-associated HD superfamily hydrolase
FLDIGELM_01638 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FLDIGELM_01639 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
FLDIGELM_01640 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
FLDIGELM_01641 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FLDIGELM_01642 8.4e-19 S YqzL-like protein
FLDIGELM_01643 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
FLDIGELM_01644 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
FLDIGELM_01645 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
FLDIGELM_01646 4.5e-112 ccpN K CBS domain
FLDIGELM_01647 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
FLDIGELM_01648 4.5e-88 yaiI S Belongs to the UPF0178 family
FLDIGELM_01649 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
FLDIGELM_01650 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FLDIGELM_01651 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
FLDIGELM_01652 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
FLDIGELM_01653 3.1e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FLDIGELM_01654 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FLDIGELM_01655 3.6e-12 yqfQ S YqfQ-like protein
FLDIGELM_01656 2.9e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
FLDIGELM_01657 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FLDIGELM_01658 2.1e-36 yqfT S Protein of unknown function (DUF2624)
FLDIGELM_01659 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
FLDIGELM_01660 4.2e-77 zur P Belongs to the Fur family
FLDIGELM_01661 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
FLDIGELM_01662 2.8e-61 yqfX S membrane
FLDIGELM_01663 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FLDIGELM_01664 5.2e-47 yqfZ M LysM domain
FLDIGELM_01665 2.2e-75 yqgA
FLDIGELM_01666 8.5e-134 yqgB S Protein of unknown function (DUF1189)
FLDIGELM_01667 4e-73 yqgC S protein conserved in bacteria
FLDIGELM_01668 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
FLDIGELM_01669 2.5e-231 yqgE EGP Major facilitator superfamily
FLDIGELM_01670 0.0 pbpA 3.4.16.4 M penicillin-binding protein
FLDIGELM_01671 3.4e-150 pstS P Phosphate
FLDIGELM_01672 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
FLDIGELM_01673 4.4e-158 pstA P Phosphate transport system permease
FLDIGELM_01674 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FLDIGELM_01675 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FLDIGELM_01676 1.9e-75 yqzC S YceG-like family
FLDIGELM_01677 9.2e-51 yqzD
FLDIGELM_01679 2.3e-26 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
FLDIGELM_01680 3.7e-168 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
FLDIGELM_01681 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FLDIGELM_01682 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FLDIGELM_01683 2.5e-09 yqgO
FLDIGELM_01684 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
FLDIGELM_01685 3.1e-33 yqgQ S Protein conserved in bacteria
FLDIGELM_01686 5.2e-181 glcK 2.7.1.2 G Glucokinase
FLDIGELM_01687 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FLDIGELM_01688 2.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
FLDIGELM_01689 2.7e-199 yqgU
FLDIGELM_01690 6.9e-50 yqgV S Thiamine-binding protein
FLDIGELM_01691 8.9e-23 yqgW S Protein of unknown function (DUF2759)
FLDIGELM_01692 1.8e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
FLDIGELM_01693 1.8e-37 yqgY S Protein of unknown function (DUF2626)
FLDIGELM_01694 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
FLDIGELM_01696 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FLDIGELM_01697 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
FLDIGELM_01698 8.8e-173 corA P Mg2 transporter protein
FLDIGELM_01699 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FLDIGELM_01700 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
FLDIGELM_01701 1.4e-47 comGC U Required for transformation and DNA binding
FLDIGELM_01702 4.4e-71 gspH NU protein transport across the cell outer membrane
FLDIGELM_01703 1.1e-59 comGE
FLDIGELM_01704 5.5e-49 comGF U Putative Competence protein ComGF
FLDIGELM_01705 3.7e-42 S ComG operon protein 7
FLDIGELM_01706 1.4e-26 yqzE S YqzE-like protein
FLDIGELM_01707 7.3e-54 yqzG S Protein of unknown function (DUF3889)
FLDIGELM_01708 2.8e-113 yqxM
FLDIGELM_01709 2.5e-58 sipW 3.4.21.89 U Signal peptidase
FLDIGELM_01710 1.9e-141 tasA S Cell division protein FtsN
FLDIGELM_01711 1e-54 sinR K transcriptional
FLDIGELM_01712 1.2e-24 sinI S Anti-repressor SinI
FLDIGELM_01713 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
FLDIGELM_01714 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
FLDIGELM_01715 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
FLDIGELM_01716 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLDIGELM_01717 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FLDIGELM_01718 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
FLDIGELM_01719 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
FLDIGELM_01720 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
FLDIGELM_01721 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
FLDIGELM_01722 2.2e-61 yqhP
FLDIGELM_01723 2.1e-174 yqhQ S Protein of unknown function (DUF1385)
FLDIGELM_01724 2.3e-93 yqhR S Conserved membrane protein YqhR
FLDIGELM_01725 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
FLDIGELM_01726 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
FLDIGELM_01727 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FLDIGELM_01728 7.9e-37 yqhV S Protein of unknown function (DUF2619)
FLDIGELM_01729 1.2e-171 spoIIIAA S stage III sporulation protein AA
FLDIGELM_01730 2.9e-85 spoIIIAB S Stage III sporulation protein
FLDIGELM_01731 7.6e-29 spoIIIAC S stage III sporulation protein AC
FLDIGELM_01732 2.3e-58 spoIIIAD S Stage III sporulation protein AD
FLDIGELM_01733 1.3e-197 spoIIIAE S stage III sporulation protein AE
FLDIGELM_01734 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
FLDIGELM_01735 6.9e-103 spoIIIAG S stage III sporulation protein AG
FLDIGELM_01736 9.9e-91 spoIIIAH S SpoIIIAH-like protein
FLDIGELM_01737 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FLDIGELM_01738 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
FLDIGELM_01739 2.1e-67 yqhY S protein conserved in bacteria
FLDIGELM_01740 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FLDIGELM_01741 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FLDIGELM_01742 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FLDIGELM_01743 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FLDIGELM_01744 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FLDIGELM_01745 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FLDIGELM_01746 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
FLDIGELM_01747 1.7e-78 argR K Regulates arginine biosynthesis genes
FLDIGELM_01748 0.0 recN L May be involved in recombinational repair of damaged DNA
FLDIGELM_01749 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
FLDIGELM_01750 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
FLDIGELM_01752 8.9e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
FLDIGELM_01753 6e-27
FLDIGELM_01754 2.7e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
FLDIGELM_01755 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FLDIGELM_01756 3.5e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
FLDIGELM_01757 1e-156 hbdA 1.1.1.157 I Dehydrogenase
FLDIGELM_01758 2e-211 mmgC I acyl-CoA dehydrogenase
FLDIGELM_01759 1.7e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
FLDIGELM_01760 5.3e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
FLDIGELM_01761 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FLDIGELM_01762 4e-34 yqzF S Protein of unknown function (DUF2627)
FLDIGELM_01763 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
FLDIGELM_01764 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
FLDIGELM_01765 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
FLDIGELM_01766 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
FLDIGELM_01767 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FLDIGELM_01768 7.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FLDIGELM_01769 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FLDIGELM_01770 9.2e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FLDIGELM_01771 1.4e-150 bmrR K helix_turn_helix, mercury resistance
FLDIGELM_01772 7.9e-208 norA EGP Major facilitator Superfamily
FLDIGELM_01773 3.4e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
FLDIGELM_01774 9.3e-77 yqiW S Belongs to the UPF0403 family
FLDIGELM_01775 1.8e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
FLDIGELM_01776 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
FLDIGELM_01777 7.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FLDIGELM_01778 9.6e-175 yqjA S Putative aromatic acid exporter C-terminal domain
FLDIGELM_01779 3e-98 yqjB S protein conserved in bacteria
FLDIGELM_01781 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
FLDIGELM_01782 1.8e-289 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
FLDIGELM_01783 1.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
FLDIGELM_01784 9.8e-140 yqjF S Uncharacterized conserved protein (COG2071)
FLDIGELM_01785 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FLDIGELM_01786 4.5e-24 yqzJ
FLDIGELM_01787 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLDIGELM_01788 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FLDIGELM_01789 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FLDIGELM_01790 8.5e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
FLDIGELM_01791 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
FLDIGELM_01792 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FLDIGELM_01793 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
FLDIGELM_01794 0.0 rocB E arginine degradation protein
FLDIGELM_01795 1.1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLDIGELM_01796 8.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
FLDIGELM_01797 6.6e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_01798 4.6e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
FLDIGELM_01799 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
FLDIGELM_01800 3e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FLDIGELM_01802 1.1e-223 yqjV G Major Facilitator Superfamily
FLDIGELM_01804 2.3e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLDIGELM_01805 5.7e-50 S YolD-like protein
FLDIGELM_01806 4e-86 yqjY K acetyltransferase
FLDIGELM_01807 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
FLDIGELM_01808 5.7e-194 yqkA K GrpB protein
FLDIGELM_01809 2.8e-54 yqkB S Belongs to the HesB IscA family
FLDIGELM_01810 9.4e-39 yqkC S Protein of unknown function (DUF2552)
FLDIGELM_01811 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
FLDIGELM_01812 3.1e-12 yqkE S Protein of unknown function (DUF3886)
FLDIGELM_01813 3.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
FLDIGELM_01815 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
FLDIGELM_01816 2.6e-219 yqxK 3.6.4.12 L DNA helicase
FLDIGELM_01817 1.3e-57 ansR K Transcriptional regulator
FLDIGELM_01818 4.7e-185 ansA 3.5.1.1 EJ L-asparaginase
FLDIGELM_01819 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
FLDIGELM_01820 3.1e-235 mleN C Na H antiporter
FLDIGELM_01821 1.2e-241 mleA 1.1.1.38 C malic enzyme
FLDIGELM_01822 1.2e-29 yqkK
FLDIGELM_01823 8.2e-106 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
FLDIGELM_01824 2.4e-80 fur P Belongs to the Fur family
FLDIGELM_01825 3.7e-37 S Protein of unknown function (DUF4227)
FLDIGELM_01826 2.6e-166 xerD L recombinase XerD
FLDIGELM_01827 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
FLDIGELM_01828 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FLDIGELM_01829 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
FLDIGELM_01830 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
FLDIGELM_01831 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
FLDIGELM_01832 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLDIGELM_01833 7.4e-112 spoVAA S Stage V sporulation protein AA
FLDIGELM_01834 1e-67 spoVAB S Stage V sporulation protein AB
FLDIGELM_01835 2.3e-78 spoVAC S stage V sporulation protein AC
FLDIGELM_01836 9e-192 spoVAD I Stage V sporulation protein AD
FLDIGELM_01837 2.2e-57 spoVAEB S stage V sporulation protein
FLDIGELM_01838 1.4e-110 spoVAEA S stage V sporulation protein
FLDIGELM_01839 1.4e-273 spoVAF EG Stage V sporulation protein AF
FLDIGELM_01840 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
FLDIGELM_01841 8.1e-149 ypuA S Secreted protein
FLDIGELM_01842 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FLDIGELM_01845 4.7e-13 S PAP2 superfamily
FLDIGELM_01846 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
FLDIGELM_01847 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
FLDIGELM_01848 7.8e-55 ypuD
FLDIGELM_01849 2.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FLDIGELM_01850 7.4e-115 ribE 2.5.1.9 H Riboflavin synthase
FLDIGELM_01851 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FLDIGELM_01852 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
FLDIGELM_01853 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FLDIGELM_01854 4.5e-94 ypuF S Domain of unknown function (DUF309)
FLDIGELM_01855 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FLDIGELM_01856 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FLDIGELM_01857 4e-98 ypuI S Protein of unknown function (DUF3907)
FLDIGELM_01858 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
FLDIGELM_01859 3.5e-103 spmA S Spore maturation protein
FLDIGELM_01860 1.9e-87 spmB S Spore maturation protein
FLDIGELM_01861 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
FLDIGELM_01862 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
FLDIGELM_01863 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
FLDIGELM_01864 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
FLDIGELM_01865 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_01866 0.0 resE 2.7.13.3 T Histidine kinase
FLDIGELM_01867 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
FLDIGELM_01868 6.8e-201 rsiX
FLDIGELM_01869 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
FLDIGELM_01870 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLDIGELM_01871 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FLDIGELM_01872 4.7e-41 fer C Ferredoxin
FLDIGELM_01873 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
FLDIGELM_01874 3.2e-286 recQ 3.6.4.12 L DNA helicase
FLDIGELM_01875 2.2e-100 ypbD S metal-dependent membrane protease
FLDIGELM_01876 4.6e-81 ypbE M Lysin motif
FLDIGELM_01877 2.8e-81 ypbF S Protein of unknown function (DUF2663)
FLDIGELM_01878 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
FLDIGELM_01879 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
FLDIGELM_01880 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
FLDIGELM_01881 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
FLDIGELM_01882 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
FLDIGELM_01883 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
FLDIGELM_01884 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
FLDIGELM_01885 9.2e-113 ypfA M Flagellar protein YcgR
FLDIGELM_01886 1.8e-23 S Family of unknown function (DUF5359)
FLDIGELM_01887 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
FLDIGELM_01888 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
FLDIGELM_01889 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
FLDIGELM_01890 1e-07 S YpzI-like protein
FLDIGELM_01891 1.3e-102 yphA
FLDIGELM_01892 2.5e-161 seaA S YIEGIA protein
FLDIGELM_01893 1.6e-28 ypzH
FLDIGELM_01894 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
FLDIGELM_01895 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
FLDIGELM_01896 1.6e-18 yphE S Protein of unknown function (DUF2768)
FLDIGELM_01897 5.4e-138 yphF
FLDIGELM_01898 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FLDIGELM_01899 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FLDIGELM_01900 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
FLDIGELM_01901 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
FLDIGELM_01902 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
FLDIGELM_01903 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
FLDIGELM_01904 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
FLDIGELM_01905 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
FLDIGELM_01906 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
FLDIGELM_01907 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FLDIGELM_01908 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FLDIGELM_01909 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
FLDIGELM_01910 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLDIGELM_01911 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FLDIGELM_01912 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
FLDIGELM_01913 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
FLDIGELM_01914 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FLDIGELM_01915 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
FLDIGELM_01916 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FLDIGELM_01917 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
FLDIGELM_01918 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
FLDIGELM_01919 4.1e-234 S COG0457 FOG TPR repeat
FLDIGELM_01920 2.8e-99 ypiB S Belongs to the UPF0302 family
FLDIGELM_01921 8.5e-78 ypiF S Protein of unknown function (DUF2487)
FLDIGELM_01922 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
FLDIGELM_01923 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
FLDIGELM_01924 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
FLDIGELM_01925 2e-98 ypjA S membrane
FLDIGELM_01926 6.1e-143 ypjB S sporulation protein
FLDIGELM_01927 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
FLDIGELM_01928 2.6e-55 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
FLDIGELM_01929 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
FLDIGELM_01930 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
FLDIGELM_01931 6.9e-130 bshB1 S proteins, LmbE homologs
FLDIGELM_01932 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
FLDIGELM_01933 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FLDIGELM_01934 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FLDIGELM_01935 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
FLDIGELM_01936 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FLDIGELM_01937 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FLDIGELM_01938 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
FLDIGELM_01939 6.7e-23 ypmA S Protein of unknown function (DUF4264)
FLDIGELM_01940 3.4e-80 ypmB S protein conserved in bacteria
FLDIGELM_01941 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
FLDIGELM_01942 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
FLDIGELM_01943 5.7e-129 dnaD L DNA replication protein DnaD
FLDIGELM_01944 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FLDIGELM_01945 4.7e-93 ypoC
FLDIGELM_01946 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
FLDIGELM_01947 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FLDIGELM_01948 2.6e-188 yppC S Protein of unknown function (DUF2515)
FLDIGELM_01951 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
FLDIGELM_01953 1.2e-48 yppG S YppG-like protein
FLDIGELM_01954 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
FLDIGELM_01955 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
FLDIGELM_01956 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
FLDIGELM_01957 1.3e-237 yprB L RNase_H superfamily
FLDIGELM_01958 3.3e-92 ypsA S Belongs to the UPF0398 family
FLDIGELM_01959 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
FLDIGELM_01960 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
FLDIGELM_01962 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
FLDIGELM_01963 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDIGELM_01964 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
FLDIGELM_01965 3.9e-187 ptxS K transcriptional
FLDIGELM_01966 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
FLDIGELM_01967 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
FLDIGELM_01968 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
FLDIGELM_01969 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FLDIGELM_01970 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
FLDIGELM_01971 1.6e-228 pbuX F xanthine
FLDIGELM_01972 4.4e-208 bcsA Q Naringenin-chalcone synthase
FLDIGELM_01973 5.1e-87 ypbQ S protein conserved in bacteria
FLDIGELM_01974 0.0 ypbR S Dynamin family
FLDIGELM_01975 1e-38 ypbS S Protein of unknown function (DUF2533)
FLDIGELM_01976 2e-07
FLDIGELM_01977 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
FLDIGELM_01979 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
FLDIGELM_01980 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FLDIGELM_01981 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
FLDIGELM_01982 2.6e-27 ypeQ S Zinc-finger
FLDIGELM_01983 8.1e-31 S Protein of unknown function (DUF2564)
FLDIGELM_01984 3.8e-16 degR
FLDIGELM_01985 7.9e-31 cspD K Cold-shock protein
FLDIGELM_01986 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
FLDIGELM_01987 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FLDIGELM_01988 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
FLDIGELM_01989 3.1e-110 ypgQ S phosphohydrolase
FLDIGELM_01990 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
FLDIGELM_01991 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
FLDIGELM_01992 1.7e-75 yphP S Belongs to the UPF0403 family
FLDIGELM_01993 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
FLDIGELM_01994 7.8e-114 ypjP S YpjP-like protein
FLDIGELM_01995 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
FLDIGELM_01996 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FLDIGELM_01997 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FLDIGELM_01998 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
FLDIGELM_01999 4.2e-110 hlyIII S protein, Hemolysin III
FLDIGELM_02000 1.6e-185 pspF K Transcriptional regulator
FLDIGELM_02001 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FLDIGELM_02002 3.1e-40 ypmP S Protein of unknown function (DUF2535)
FLDIGELM_02003 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
FLDIGELM_02004 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
FLDIGELM_02005 5e-99 ypmS S protein conserved in bacteria
FLDIGELM_02006 5.5e-29 ypmT S Uncharacterized ympT
FLDIGELM_02007 2.6e-223 mepA V MATE efflux family protein
FLDIGELM_02008 1.6e-70 ypoP K transcriptional
FLDIGELM_02009 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FLDIGELM_02010 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
FLDIGELM_02011 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
FLDIGELM_02012 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
FLDIGELM_02013 3.3e-188 cgeB S Spore maturation protein
FLDIGELM_02014 1.2e-65 cgeA
FLDIGELM_02015 3.5e-38 cgeC
FLDIGELM_02016 1e-256 cgeD M maturation of the outermost layer of the spore
FLDIGELM_02017 2.9e-145 yiiD K acetyltransferase
FLDIGELM_02020 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLDIGELM_02021 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FLDIGELM_02022 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
FLDIGELM_02023 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
FLDIGELM_02024 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
FLDIGELM_02025 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
FLDIGELM_02026 2.9e-47 yokU S YokU-like protein, putative antitoxin
FLDIGELM_02027 1.4e-36 yozE S Belongs to the UPF0346 family
FLDIGELM_02028 1.4e-124 yodN
FLDIGELM_02030 2.8e-24 yozD S YozD-like protein
FLDIGELM_02031 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
FLDIGELM_02032 3.6e-54 yodL S YodL-like
FLDIGELM_02033 5.3e-09
FLDIGELM_02034 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
FLDIGELM_02035 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
FLDIGELM_02036 5.2e-24 yodI
FLDIGELM_02037 1.7e-128 yodH Q Methyltransferase
FLDIGELM_02038 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
FLDIGELM_02039 1.6e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLDIGELM_02040 6.2e-28 S Protein of unknown function (DUF3311)
FLDIGELM_02041 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
FLDIGELM_02042 3.8e-113 mhqD S Carboxylesterase
FLDIGELM_02043 4.8e-108 yodC C nitroreductase
FLDIGELM_02044 1.7e-57 yodB K transcriptional
FLDIGELM_02045 3.8e-66 yodA S tautomerase
FLDIGELM_02046 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
FLDIGELM_02047 3.4e-09
FLDIGELM_02048 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
FLDIGELM_02049 3.5e-163 rarD S -transporter
FLDIGELM_02050 1.5e-43
FLDIGELM_02051 2.2e-60 yojF S Protein of unknown function (DUF1806)
FLDIGELM_02052 2.1e-125 yojG S deacetylase
FLDIGELM_02053 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FLDIGELM_02054 4.2e-245 norM V Multidrug efflux pump
FLDIGELM_02056 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FLDIGELM_02057 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
FLDIGELM_02058 4.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
FLDIGELM_02059 1.5e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FLDIGELM_02060 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
FLDIGELM_02061 0.0 yojO P Von Willebrand factor
FLDIGELM_02062 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
FLDIGELM_02063 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
FLDIGELM_02064 5.6e-167 yocS S -transporter
FLDIGELM_02065 3.8e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
FLDIGELM_02066 2.1e-165 sodA 1.15.1.1 P Superoxide dismutase
FLDIGELM_02067 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
FLDIGELM_02068 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
FLDIGELM_02069 2.7e-31 yozC
FLDIGELM_02070 4.2e-56 yozO S Bacterial PH domain
FLDIGELM_02071 1.9e-36 yocN
FLDIGELM_02072 1.1e-40 yozN
FLDIGELM_02073 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
FLDIGELM_02074 6.6e-34
FLDIGELM_02075 6.4e-54 yocL
FLDIGELM_02076 3.3e-83 dksA T general stress protein
FLDIGELM_02077 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FLDIGELM_02078 0.0 recQ 3.6.4.12 L DNA helicase
FLDIGELM_02079 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
FLDIGELM_02080 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FLDIGELM_02081 3.2e-198 desK 2.7.13.3 T Histidine kinase
FLDIGELM_02082 9.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
FLDIGELM_02083 7.9e-185 yocD 3.4.17.13 V peptidase S66
FLDIGELM_02084 1.6e-93 yocC
FLDIGELM_02085 4.9e-13
FLDIGELM_02086 1.4e-101
FLDIGELM_02087 1.5e-92 yozB S membrane
FLDIGELM_02088 2.4e-108 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
FLDIGELM_02089 1e-51 czrA K transcriptional
FLDIGELM_02090 4.7e-94 yobW
FLDIGELM_02091 9e-178 yobV K WYL domain
FLDIGELM_02092 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
FLDIGELM_02093 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
FLDIGELM_02094 3e-99 yobS K Transcriptional regulator
FLDIGELM_02095 2.5e-143 yobR 2.3.1.1 J FR47-like protein
FLDIGELM_02096 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
FLDIGELM_02097 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
FLDIGELM_02098 0.0 yobO M Pectate lyase superfamily protein
FLDIGELM_02099 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
FLDIGELM_02100 7.9e-105 yokH G SMI1 / KNR4 family
FLDIGELM_02101 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
FLDIGELM_02102 3e-86 S SMI1-KNR4 cell-wall
FLDIGELM_02103 2.7e-157 yobJ
FLDIGELM_02104 0.0 K Psort location Cytoplasmic, score
FLDIGELM_02105 1.2e-49
FLDIGELM_02106 2.6e-38 S YolD-like protein
FLDIGELM_02107 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLDIGELM_02108 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FLDIGELM_02110 1.7e-207 S aspartate phosphatase
FLDIGELM_02115 1.8e-178 yobF
FLDIGELM_02116 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
FLDIGELM_02117 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
FLDIGELM_02119 5.7e-58 K Helix-turn-helix
FLDIGELM_02120 1.4e-37 S TM2 domain
FLDIGELM_02121 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
FLDIGELM_02122 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
FLDIGELM_02126 2.3e-170 bla 3.5.2.6 V beta-lactamase
FLDIGELM_02127 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
FLDIGELM_02128 3.7e-78 yoaW
FLDIGELM_02129 6e-160 yijE EG EamA-like transporter family
FLDIGELM_02130 8.6e-159 yoaU K LysR substrate binding domain
FLDIGELM_02131 1.1e-149 yoaT S Protein of unknown function (DUF817)
FLDIGELM_02132 4.2e-37 yozG K Transcriptional regulator
FLDIGELM_02133 4.3e-75 yoaS S Protein of unknown function (DUF2975)
FLDIGELM_02134 2.4e-172 yoaR V vancomycin resistance protein
FLDIGELM_02135 4.1e-89
FLDIGELM_02136 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
FLDIGELM_02137 1.9e-146 yoaP 3.1.3.18 K YoaP-like
FLDIGELM_02139 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
FLDIGELM_02141 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
FLDIGELM_02142 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
FLDIGELM_02143 2.3e-111 yoaK S Membrane
FLDIGELM_02144 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
FLDIGELM_02145 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
FLDIGELM_02146 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
FLDIGELM_02147 1.5e-38 S Protein of unknown function (DUF4025)
FLDIGELM_02148 7e-14
FLDIGELM_02149 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
FLDIGELM_02150 1.9e-33 yoaF
FLDIGELM_02151 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FLDIGELM_02152 4.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FLDIGELM_02153 6.7e-281 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
FLDIGELM_02154 6.2e-235 yoaB EGP Major facilitator Superfamily
FLDIGELM_02155 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FLDIGELM_02156 3.1e-144 yoxB
FLDIGELM_02157 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
FLDIGELM_02158 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_02159 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
FLDIGELM_02160 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FLDIGELM_02161 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FLDIGELM_02162 7.8e-155 gltC K Transcriptional regulator
FLDIGELM_02163 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
FLDIGELM_02164 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
FLDIGELM_02165 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
FLDIGELM_02166 2.5e-158 gltR1 K Transcriptional regulator
FLDIGELM_02167 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
FLDIGELM_02168 3e-34 yoeD G Helix-turn-helix domain
FLDIGELM_02169 2.2e-96 L Integrase
FLDIGELM_02171 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
FLDIGELM_02172 2.3e-246 yoeA V MATE efflux family protein
FLDIGELM_02173 9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
FLDIGELM_02174 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
FLDIGELM_02179 7.8e-08
FLDIGELM_02187 2e-08
FLDIGELM_02191 2.7e-143 spo0M S COG4326 Sporulation control protein
FLDIGELM_02192 3e-27
FLDIGELM_02193 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
FLDIGELM_02194 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FLDIGELM_02195 1.9e-266 ygaK C Berberine and berberine like
FLDIGELM_02197 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
FLDIGELM_02198 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
FLDIGELM_02199 1.6e-169 ssuA M Sulfonate ABC transporter
FLDIGELM_02200 4.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
FLDIGELM_02201 2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
FLDIGELM_02203 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLDIGELM_02204 3.8e-76 ygaO
FLDIGELM_02205 4.4e-29 K Transcriptional regulator
FLDIGELM_02207 8.7e-113 yhzB S B3/4 domain
FLDIGELM_02208 6e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FLDIGELM_02209 1.1e-175 yhbB S Putative amidase domain
FLDIGELM_02210 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FLDIGELM_02211 7.9e-109 yhbD K Protein of unknown function (DUF4004)
FLDIGELM_02212 5.4e-58 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
FLDIGELM_02213 9.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
FLDIGELM_02214 0.0 prkA T Ser protein kinase
FLDIGELM_02215 2.5e-225 yhbH S Belongs to the UPF0229 family
FLDIGELM_02216 2.2e-76 yhbI K DNA-binding transcription factor activity
FLDIGELM_02217 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
FLDIGELM_02218 3.1e-271 yhcA EGP Major facilitator Superfamily
FLDIGELM_02219 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
FLDIGELM_02220 2.8e-37 yhcC
FLDIGELM_02221 7.8e-55
FLDIGELM_02222 6.6e-60 yhcF K Transcriptional regulator
FLDIGELM_02223 1.6e-123 yhcG V ABC transporter, ATP-binding protein
FLDIGELM_02224 2.6e-166 yhcH V ABC transporter, ATP-binding protein
FLDIGELM_02225 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FLDIGELM_02226 1e-30 cspB K Cold-shock protein
FLDIGELM_02227 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
FLDIGELM_02228 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
FLDIGELM_02229 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FLDIGELM_02230 2.9e-28 yhcM
FLDIGELM_02231 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FLDIGELM_02232 2.5e-167 yhcP
FLDIGELM_02233 5.2e-100 yhcQ M Spore coat protein
FLDIGELM_02234 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
FLDIGELM_02235 4.6e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
FLDIGELM_02236 3e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FLDIGELM_02237 9.3e-68 yhcU S Family of unknown function (DUF5365)
FLDIGELM_02238 9.9e-68 yhcV S COG0517 FOG CBS domain
FLDIGELM_02239 7.8e-120 yhcW 5.4.2.6 S hydrolase
FLDIGELM_02240 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
FLDIGELM_02241 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLDIGELM_02242 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
FLDIGELM_02243 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
FLDIGELM_02244 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FLDIGELM_02245 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FLDIGELM_02246 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
FLDIGELM_02247 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
FLDIGELM_02248 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FLDIGELM_02249 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
FLDIGELM_02250 1.2e-38 yhdB S YhdB-like protein
FLDIGELM_02251 4.8e-54 yhdC S Protein of unknown function (DUF3889)
FLDIGELM_02252 9e-185 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
FLDIGELM_02253 1e-75 nsrR K Transcriptional regulator
FLDIGELM_02254 4.3e-238 ygxB M Conserved TM helix
FLDIGELM_02255 2.1e-276 ycgB S Stage V sporulation protein R
FLDIGELM_02256 2.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
FLDIGELM_02257 1.4e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
FLDIGELM_02258 3.8e-162 citR K Transcriptional regulator
FLDIGELM_02259 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
FLDIGELM_02260 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDIGELM_02261 3.4e-250 yhdG E amino acid
FLDIGELM_02262 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
FLDIGELM_02263 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FLDIGELM_02264 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FLDIGELM_02265 8.1e-45 yhdK S Sigma-M inhibitor protein
FLDIGELM_02266 6.6e-201 yhdL S Sigma factor regulator N-terminal
FLDIGELM_02267 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
FLDIGELM_02268 1.5e-191 yhdN C Aldo keto reductase
FLDIGELM_02269 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
FLDIGELM_02270 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
FLDIGELM_02271 4.1e-74 cueR K transcriptional
FLDIGELM_02272 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
FLDIGELM_02273 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
FLDIGELM_02274 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLDIGELM_02275 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FLDIGELM_02276 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FLDIGELM_02278 6.6e-204 yhdY M Mechanosensitive ion channel
FLDIGELM_02279 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
FLDIGELM_02280 1.7e-151 yheN G deacetylase
FLDIGELM_02281 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
FLDIGELM_02282 2.2e-233 nhaC C Na H antiporter
FLDIGELM_02283 3.4e-84 nhaX T Belongs to the universal stress protein A family
FLDIGELM_02284 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
FLDIGELM_02285 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
FLDIGELM_02286 3.7e-111 yheG GM NAD(P)H-binding
FLDIGELM_02287 6.3e-28 sspB S spore protein
FLDIGELM_02288 1.3e-36 yheE S Family of unknown function (DUF5342)
FLDIGELM_02289 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
FLDIGELM_02290 4.3e-216 yheC HJ YheC/D like ATP-grasp
FLDIGELM_02291 6.7e-204 yheB S Belongs to the UPF0754 family
FLDIGELM_02292 9.5e-48 yheA S Belongs to the UPF0342 family
FLDIGELM_02293 3.1e-206 yhaZ L DNA alkylation repair enzyme
FLDIGELM_02294 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
FLDIGELM_02295 7.1e-294 hemZ H coproporphyrinogen III oxidase
FLDIGELM_02296 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
FLDIGELM_02297 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
FLDIGELM_02299 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
FLDIGELM_02300 1.1e-26 S YhzD-like protein
FLDIGELM_02301 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
FLDIGELM_02302 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
FLDIGELM_02303 3.6e-227 yhaO L DNA repair exonuclease
FLDIGELM_02304 0.0 yhaN L AAA domain
FLDIGELM_02305 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
FLDIGELM_02306 1.6e-21 yhaL S Sporulation protein YhaL
FLDIGELM_02307 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
FLDIGELM_02308 8.7e-90 yhaK S Putative zincin peptidase
FLDIGELM_02309 1.3e-54 yhaI S Protein of unknown function (DUF1878)
FLDIGELM_02310 1e-113 hpr K Negative regulator of protease production and sporulation
FLDIGELM_02311 7e-39 yhaH S YtxH-like protein
FLDIGELM_02312 3.6e-80 trpP S Tryptophan transporter TrpP
FLDIGELM_02313 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FLDIGELM_02314 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
FLDIGELM_02315 4.6e-137 ecsA V transporter (ATP-binding protein)
FLDIGELM_02316 1.8e-215 ecsB U ABC transporter
FLDIGELM_02317 4.8e-115 ecsC S EcsC protein family
FLDIGELM_02318 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
FLDIGELM_02319 4.2e-248 yhfA C membrane
FLDIGELM_02320 7.5e-17 1.15.1.2 C Rubrerythrin
FLDIGELM_02321 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
FLDIGELM_02322 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
FLDIGELM_02323 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FLDIGELM_02324 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
FLDIGELM_02325 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FLDIGELM_02326 1.4e-101 yhgD K Transcriptional regulator
FLDIGELM_02327 1e-238 yhgE S YhgE Pip N-terminal domain protein
FLDIGELM_02328 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLDIGELM_02329 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
FLDIGELM_02330 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
FLDIGELM_02331 1.7e-72 3.4.13.21 S ASCH
FLDIGELM_02332 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FLDIGELM_02333 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
FLDIGELM_02334 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
FLDIGELM_02335 2.6e-112 yhfK GM NmrA-like family
FLDIGELM_02336 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
FLDIGELM_02337 1.9e-65 yhfM
FLDIGELM_02338 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
FLDIGELM_02339 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
FLDIGELM_02340 7.3e-77 VY92_01935 K acetyltransferase
FLDIGELM_02341 7e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
FLDIGELM_02342 4.8e-158 yfmC M Periplasmic binding protein
FLDIGELM_02343 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
FLDIGELM_02344 6.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
FLDIGELM_02345 1.8e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
FLDIGELM_02346 1.9e-90 bioY S BioY family
FLDIGELM_02347 1.7e-182 hemAT NT chemotaxis protein
FLDIGELM_02348 2.3e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
FLDIGELM_02349 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDIGELM_02350 1.3e-32 yhzC S IDEAL
FLDIGELM_02351 4.2e-109 comK K Competence transcription factor
FLDIGELM_02352 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
FLDIGELM_02353 7.8e-42 yhjA S Excalibur calcium-binding domain
FLDIGELM_02354 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLDIGELM_02355 6.9e-27 yhjC S Protein of unknown function (DUF3311)
FLDIGELM_02356 5e-60 yhjD
FLDIGELM_02357 9.1e-110 yhjE S SNARE associated Golgi protein
FLDIGELM_02358 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
FLDIGELM_02359 1.1e-286 yhjG CH FAD binding domain
FLDIGELM_02360 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
FLDIGELM_02361 6.9e-215 glcP G Major Facilitator Superfamily
FLDIGELM_02362 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
FLDIGELM_02363 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
FLDIGELM_02364 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
FLDIGELM_02365 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
FLDIGELM_02366 2.4e-201 abrB S membrane
FLDIGELM_02367 3.1e-215 EGP Transmembrane secretion effector
FLDIGELM_02368 0.0 S Sugar transport-related sRNA regulator N-term
FLDIGELM_02369 2e-36 yhjQ C COG1145 Ferredoxin
FLDIGELM_02370 2.2e-78 yhjR S Rubrerythrin
FLDIGELM_02371 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
FLDIGELM_02372 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
FLDIGELM_02373 3.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
FLDIGELM_02374 0.0 sbcC L COG0419 ATPase involved in DNA repair
FLDIGELM_02375 1.1e-49 yisB V COG1403 Restriction endonuclease
FLDIGELM_02376 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
FLDIGELM_02377 3e-66 gerPE S Spore germination protein GerPE
FLDIGELM_02378 6.3e-24 gerPD S Spore germination protein
FLDIGELM_02379 2.5e-51 gerPC S Spore germination protein
FLDIGELM_02380 4e-34 gerPB S cell differentiation
FLDIGELM_02381 1.9e-33 gerPA S Spore germination protein
FLDIGELM_02382 1.5e-22 yisI S Spo0E like sporulation regulatory protein
FLDIGELM_02383 1e-173 cotH M Spore Coat
FLDIGELM_02384 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
FLDIGELM_02385 3e-57 yisL S UPF0344 protein
FLDIGELM_02386 0.0 wprA O Belongs to the peptidase S8 family
FLDIGELM_02387 3.6e-102 yisN S Protein of unknown function (DUF2777)
FLDIGELM_02388 0.0 asnO 6.3.5.4 E Asparagine synthase
FLDIGELM_02389 4.7e-88 yizA S Damage-inducible protein DinB
FLDIGELM_02390 9.1e-147 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
FLDIGELM_02391 4e-243 yisQ V Mate efflux family protein
FLDIGELM_02392 4.5e-160 yisR K Transcriptional regulator
FLDIGELM_02393 2.4e-184 purR K helix_turn _helix lactose operon repressor
FLDIGELM_02394 4.8e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
FLDIGELM_02395 7e-92 yisT S DinB family
FLDIGELM_02396 1.4e-99 argO S Lysine exporter protein LysE YggA
FLDIGELM_02397 4e-270 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FLDIGELM_02398 4e-36 mcbG S Pentapeptide repeats (9 copies)
FLDIGELM_02399 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FLDIGELM_02400 1.9e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
FLDIGELM_02401 2.7e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
FLDIGELM_02402 2.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
FLDIGELM_02403 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
FLDIGELM_02404 1.9e-141 yitD 4.4.1.19 S synthase
FLDIGELM_02405 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
FLDIGELM_02406 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
FLDIGELM_02407 1.5e-228 yitG EGP Major facilitator Superfamily
FLDIGELM_02408 2.4e-153 yitH K Acetyltransferase (GNAT) domain
FLDIGELM_02409 4.6e-71 yjcF S Acetyltransferase (GNAT) domain
FLDIGELM_02410 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
FLDIGELM_02411 8.6e-55 yajQ S Belongs to the UPF0234 family
FLDIGELM_02412 3.4e-160 cvfB S protein conserved in bacteria
FLDIGELM_02413 8.5e-94
FLDIGELM_02414 1.4e-170
FLDIGELM_02415 1.5e-97 S Sporulation delaying protein SdpA
FLDIGELM_02416 1.5e-58 K Transcriptional regulator PadR-like family
FLDIGELM_02417 2e-95
FLDIGELM_02418 1.4e-44 yitR S Domain of unknown function (DUF3784)
FLDIGELM_02419 2.2e-311 nprB 3.4.24.28 E Peptidase M4
FLDIGELM_02420 8.4e-159 yitS S protein conserved in bacteria
FLDIGELM_02421 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
FLDIGELM_02422 1.9e-72 ipi S Intracellular proteinase inhibitor
FLDIGELM_02423 1.2e-17 S Protein of unknown function (DUF3813)
FLDIGELM_02424 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
FLDIGELM_02425 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
FLDIGELM_02426 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
FLDIGELM_02427 1.5e-22 pilT S Proteolipid membrane potential modulator
FLDIGELM_02428 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
FLDIGELM_02429 1.7e-88 norB G Major Facilitator Superfamily
FLDIGELM_02430 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FLDIGELM_02431 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FLDIGELM_02432 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
FLDIGELM_02433 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
FLDIGELM_02434 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FLDIGELM_02435 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
FLDIGELM_02436 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FLDIGELM_02437 9.5e-28 yjzC S YjzC-like protein
FLDIGELM_02438 2.3e-16 yjzD S Protein of unknown function (DUF2929)
FLDIGELM_02439 6.2e-142 yjaU I carboxylic ester hydrolase activity
FLDIGELM_02440 7.3e-103 yjaV
FLDIGELM_02441 1.1e-183 med S Transcriptional activator protein med
FLDIGELM_02442 7.3e-26 comZ S ComZ
FLDIGELM_02443 2.7e-22 yjzB
FLDIGELM_02444 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FLDIGELM_02445 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FLDIGELM_02446 7.8e-151 yjaZ O Zn-dependent protease
FLDIGELM_02447 1.8e-184 appD P Belongs to the ABC transporter superfamily
FLDIGELM_02448 6.5e-187 appF E Belongs to the ABC transporter superfamily
FLDIGELM_02449 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
FLDIGELM_02450 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLDIGELM_02451 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLDIGELM_02452 5e-147 yjbA S Belongs to the UPF0736 family
FLDIGELM_02453 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
FLDIGELM_02454 0.0 oppA E ABC transporter substrate-binding protein
FLDIGELM_02455 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLDIGELM_02456 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLDIGELM_02457 3e-198 oppD P Belongs to the ABC transporter superfamily
FLDIGELM_02458 5.5e-172 oppF E Belongs to the ABC transporter superfamily
FLDIGELM_02459 8.6e-196 yjbB EGP Major Facilitator Superfamily
FLDIGELM_02460 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FLDIGELM_02461 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
FLDIGELM_02462 6e-112 yjbE P Integral membrane protein TerC family
FLDIGELM_02463 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
FLDIGELM_02464 2.3e-223 yjbF S Competence protein
FLDIGELM_02465 0.0 pepF E oligoendopeptidase F
FLDIGELM_02466 1.8e-20
FLDIGELM_02468 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
FLDIGELM_02469 3.7e-72 yjbI S Bacterial-like globin
FLDIGELM_02470 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
FLDIGELM_02471 2.4e-101 yjbK S protein conserved in bacteria
FLDIGELM_02472 7.1e-62 yjbL S Belongs to the UPF0738 family
FLDIGELM_02473 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
FLDIGELM_02474 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FLDIGELM_02475 1.2e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FLDIGELM_02476 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
FLDIGELM_02477 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
FLDIGELM_02478 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FLDIGELM_02479 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
FLDIGELM_02480 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
FLDIGELM_02481 6.7e-30 thiS H thiamine diphosphate biosynthetic process
FLDIGELM_02482 4.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
FLDIGELM_02483 5.6e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
FLDIGELM_02484 5.8e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
FLDIGELM_02485 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
FLDIGELM_02486 5.9e-54 yjbX S Spore coat protein
FLDIGELM_02487 4.4e-82 cotZ S Spore coat protein
FLDIGELM_02488 7.6e-96 cotY S Spore coat protein Z
FLDIGELM_02489 1.6e-72 cotX S Spore Coat Protein X and V domain
FLDIGELM_02490 8.8e-24 cotW
FLDIGELM_02491 1.1e-54 cotV S Spore Coat Protein X and V domain
FLDIGELM_02492 4.3e-56 yjcA S Protein of unknown function (DUF1360)
FLDIGELM_02495 2.9e-38 spoVIF S Stage VI sporulation protein F
FLDIGELM_02496 0.0 yjcD 3.6.4.12 L DNA helicase
FLDIGELM_02497 1.7e-38
FLDIGELM_02498 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FLDIGELM_02499 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
FLDIGELM_02500 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
FLDIGELM_02501 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FLDIGELM_02502 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
FLDIGELM_02503 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
FLDIGELM_02504 3.9e-210 yjcL S Protein of unknown function (DUF819)
FLDIGELM_02507 1.6e-38
FLDIGELM_02508 1e-29
FLDIGELM_02509 5e-238 M nucleic acid phosphodiester bond hydrolysis
FLDIGELM_02511 1.4e-29 KLT Protein tyrosine kinase
FLDIGELM_02512 4.3e-11 S YolD-like protein
FLDIGELM_02513 1.9e-36
FLDIGELM_02514 9e-19
FLDIGELM_02516 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
FLDIGELM_02517 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
FLDIGELM_02519 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
FLDIGELM_02520 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
FLDIGELM_02521 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
FLDIGELM_02522 4.8e-51 yjdF S Protein of unknown function (DUF2992)
FLDIGELM_02523 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
FLDIGELM_02525 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FLDIGELM_02526 4.2e-29 S Domain of unknown function (DUF4177)
FLDIGELM_02527 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
FLDIGELM_02528 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
FLDIGELM_02530 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
FLDIGELM_02531 5.5e-83 S Protein of unknown function (DUF2690)
FLDIGELM_02532 3.6e-21 yjfB S Putative motility protein
FLDIGELM_02533 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
FLDIGELM_02534 1.2e-45 T PhoQ Sensor
FLDIGELM_02535 8.9e-104 yjgB S Domain of unknown function (DUF4309)
FLDIGELM_02536 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
FLDIGELM_02537 4.3e-95 yjgD S Protein of unknown function (DUF1641)
FLDIGELM_02538 8.7e-07 S Domain of unknown function (DUF4352)
FLDIGELM_02539 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
FLDIGELM_02541 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
FLDIGELM_02542 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
FLDIGELM_02543 8.2e-30
FLDIGELM_02544 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
FLDIGELM_02545 1.9e-122 ybbM S transport system, permease component
FLDIGELM_02546 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
FLDIGELM_02547 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
FLDIGELM_02548 2.8e-93 yjlB S Cupin domain
FLDIGELM_02549 7.1e-66 yjlC S Protein of unknown function (DUF1641)
FLDIGELM_02550 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
FLDIGELM_02551 3e-278 uxaC 5.3.1.12 G glucuronate isomerase
FLDIGELM_02552 1.4e-248 yjmB G symporter YjmB
FLDIGELM_02553 1.9e-186 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
FLDIGELM_02554 1.4e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
FLDIGELM_02555 8.9e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
FLDIGELM_02556 6.8e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
FLDIGELM_02557 3.7e-227 exuT G Sugar (and other) transporter
FLDIGELM_02558 1.5e-183 exuR K transcriptional
FLDIGELM_02559 4.9e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
FLDIGELM_02560 4.4e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
FLDIGELM_02561 4.3e-130 MA20_18170 S membrane transporter protein
FLDIGELM_02562 9.5e-80 yjoA S DinB family
FLDIGELM_02563 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
FLDIGELM_02564 1e-212 S response regulator aspartate phosphatase
FLDIGELM_02566 6.3e-41 S YCII-related domain
FLDIGELM_02567 2.9e-168 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
FLDIGELM_02568 1.8e-60 yjqA S Bacterial PH domain
FLDIGELM_02569 2.1e-111 yjqB S Pfam:DUF867
FLDIGELM_02570 4.4e-160 ydbD P Catalase
FLDIGELM_02571 4.3e-109 xkdA E IrrE N-terminal-like domain
FLDIGELM_02572 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
FLDIGELM_02574 5e-156 xkdB K sequence-specific DNA binding
FLDIGELM_02575 9.2e-118 xkdC L Bacterial dnaA protein
FLDIGELM_02578 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
FLDIGELM_02579 2.2e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
FLDIGELM_02580 5.3e-139 xtmA L phage terminase small subunit
FLDIGELM_02581 1.4e-253 xtmB S phage terminase, large subunit
FLDIGELM_02582 6e-285 yqbA S portal protein
FLDIGELM_02583 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
FLDIGELM_02584 2.9e-168 xkdG S Phage capsid family
FLDIGELM_02585 5.5e-65 yqbG S Protein of unknown function (DUF3199)
FLDIGELM_02586 8.7e-65 yqbH S Domain of unknown function (DUF3599)
FLDIGELM_02587 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
FLDIGELM_02588 1.9e-77 xkdJ
FLDIGELM_02589 2.5e-256 xkdK S Phage tail sheath C-terminal domain
FLDIGELM_02590 6.1e-76 xkdM S Phage tail tube protein
FLDIGELM_02591 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
FLDIGELM_02592 0.0 xkdO L Transglycosylase SLT domain
FLDIGELM_02593 3.7e-122 xkdP S Lysin motif
FLDIGELM_02594 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
FLDIGELM_02595 2.1e-39 xkdR S Protein of unknown function (DUF2577)
FLDIGELM_02596 9.6e-71 xkdS S Protein of unknown function (DUF2634)
FLDIGELM_02597 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
FLDIGELM_02598 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
FLDIGELM_02599 6.7e-41
FLDIGELM_02600 0.0
FLDIGELM_02601 2.6e-55 xkdW S XkdW protein
FLDIGELM_02602 1.7e-23 xkdX
FLDIGELM_02603 1.2e-154 xepA
FLDIGELM_02604 2.8e-39 xhlA S Haemolysin XhlA
FLDIGELM_02605 9.3e-40 xhlB S SPP1 phage holin
FLDIGELM_02606 3.8e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FLDIGELM_02608 6.7e-23 spoIISB S Stage II sporulation protein SB
FLDIGELM_02609 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
FLDIGELM_02610 5.8e-175 pit P phosphate transporter
FLDIGELM_02611 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
FLDIGELM_02612 1.8e-240 steT E amino acid
FLDIGELM_02613 2.7e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
FLDIGELM_02614 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FLDIGELM_02615 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FLDIGELM_02617 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FLDIGELM_02618 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
FLDIGELM_02619 7.9e-154 dppA E D-aminopeptidase
FLDIGELM_02620 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLDIGELM_02621 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
FLDIGELM_02622 3.4e-191 dppD P Belongs to the ABC transporter superfamily
FLDIGELM_02623 0.0 dppE E ABC transporter substrate-binding protein
FLDIGELM_02625 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
FLDIGELM_02626 2.6e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
FLDIGELM_02627 8.5e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
FLDIGELM_02628 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
FLDIGELM_02629 3.6e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
FLDIGELM_02630 2e-160 ykgA E Amidinotransferase
FLDIGELM_02631 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
FLDIGELM_02632 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FLDIGELM_02633 1e-07
FLDIGELM_02634 2.7e-129 ykjA S Protein of unknown function (DUF421)
FLDIGELM_02635 1e-98 ykkA S Protein of unknown function (DUF664)
FLDIGELM_02636 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FLDIGELM_02637 3.5e-55 ykkC P Multidrug resistance protein
FLDIGELM_02638 7e-50 ykkD P Multidrug resistance protein
FLDIGELM_02639 1.2e-168 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
FLDIGELM_02640 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FLDIGELM_02641 5.3e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FLDIGELM_02643 1.3e-70 ohrA O Organic hydroperoxide resistance protein
FLDIGELM_02644 4.8e-73 ohrR K COG1846 Transcriptional regulators
FLDIGELM_02645 8.4e-72 ohrB O Organic hydroperoxide resistance protein
FLDIGELM_02647 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
FLDIGELM_02648 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FLDIGELM_02649 5e-176 isp O Belongs to the peptidase S8 family
FLDIGELM_02650 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FLDIGELM_02651 5.3e-136 ykoC P Cobalt transport protein
FLDIGELM_02652 2.2e-304 P ABC transporter, ATP-binding protein
FLDIGELM_02653 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
FLDIGELM_02654 1.1e-109 ykoF S YKOF-related Family
FLDIGELM_02655 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_02656 2.6e-242 ykoH 2.7.13.3 T Histidine kinase
FLDIGELM_02657 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
FLDIGELM_02658 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
FLDIGELM_02661 2.2e-222 mgtE P Acts as a magnesium transporter
FLDIGELM_02662 1.4e-53 tnrA K transcriptional
FLDIGELM_02663 5.9e-18
FLDIGELM_02664 6.9e-26 ykoL
FLDIGELM_02665 1.3e-81 mhqR K transcriptional
FLDIGELM_02666 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
FLDIGELM_02667 3.7e-99 ykoP G polysaccharide deacetylase
FLDIGELM_02668 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
FLDIGELM_02669 0.0 ykoS
FLDIGELM_02670 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FLDIGELM_02671 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
FLDIGELM_02672 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FLDIGELM_02673 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
FLDIGELM_02674 1.4e-116 ykoX S membrane-associated protein
FLDIGELM_02675 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
FLDIGELM_02676 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLDIGELM_02677 8.2e-117 rsgI S Anti-sigma factor N-terminus
FLDIGELM_02678 1.9e-26 sspD S small acid-soluble spore protein
FLDIGELM_02679 1.5e-124 ykrK S Domain of unknown function (DUF1836)
FLDIGELM_02680 7e-156 htpX O Belongs to the peptidase M48B family
FLDIGELM_02681 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
FLDIGELM_02682 1.2e-10 ydfR S Protein of unknown function (DUF421)
FLDIGELM_02683 4.5e-22 ykzE
FLDIGELM_02684 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
FLDIGELM_02685 0.0 kinE 2.7.13.3 T Histidine kinase
FLDIGELM_02686 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLDIGELM_02688 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FLDIGELM_02689 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FLDIGELM_02690 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
FLDIGELM_02691 8e-232 mtnE 2.6.1.83 E Aminotransferase
FLDIGELM_02692 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
FLDIGELM_02693 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
FLDIGELM_02694 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
FLDIGELM_02695 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FLDIGELM_02696 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
FLDIGELM_02697 6.4e-09 S Spo0E like sporulation regulatory protein
FLDIGELM_02698 1.4e-64 eag
FLDIGELM_02699 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
FLDIGELM_02700 1.3e-75 ykvE K transcriptional
FLDIGELM_02701 2.5e-125 motB N Flagellar motor protein
FLDIGELM_02702 2.7e-138 motA N flagellar motor
FLDIGELM_02703 0.0 clpE O Belongs to the ClpA ClpB family
FLDIGELM_02704 8.7e-182 ykvI S membrane
FLDIGELM_02705 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FLDIGELM_02706 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
FLDIGELM_02707 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
FLDIGELM_02708 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FLDIGELM_02709 2e-61 ykvN K Transcriptional regulator
FLDIGELM_02710 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
FLDIGELM_02711 2.6e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
FLDIGELM_02712 1.2e-35 3.5.1.104 M LysM domain
FLDIGELM_02713 8.5e-133 G Glycosyl hydrolases family 18
FLDIGELM_02714 1.6e-45 ykvR S Protein of unknown function (DUF3219)
FLDIGELM_02715 6e-25 ykvS S protein conserved in bacteria
FLDIGELM_02716 2.8e-28
FLDIGELM_02717 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
FLDIGELM_02718 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FLDIGELM_02719 1.6e-88 stoA CO thiol-disulfide
FLDIGELM_02720 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
FLDIGELM_02721 3.8e-09
FLDIGELM_02722 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
FLDIGELM_02724 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
FLDIGELM_02726 4.5e-128 glcT K antiterminator
FLDIGELM_02727 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FLDIGELM_02728 2.1e-39 ptsH G phosphocarrier protein HPr
FLDIGELM_02729 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FLDIGELM_02730 7.2e-39 splA S Transcriptional regulator
FLDIGELM_02731 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
FLDIGELM_02732 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FLDIGELM_02733 2e-264 mcpC NT chemotaxis protein
FLDIGELM_02734 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
FLDIGELM_02735 8e-124 ykwD J protein with SCP PR1 domains
FLDIGELM_02736 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
FLDIGELM_02737 0.0 pilS 2.7.13.3 T Histidine kinase
FLDIGELM_02738 8e-224 patA 2.6.1.1 E Aminotransferase
FLDIGELM_02739 2.2e-15
FLDIGELM_02740 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
FLDIGELM_02741 1.7e-84 ykyB S YkyB-like protein
FLDIGELM_02742 1.6e-238 ykuC EGP Major facilitator Superfamily
FLDIGELM_02743 4.6e-88 ykuD S protein conserved in bacteria
FLDIGELM_02744 9.4e-166 ykuE S Metallophosphoesterase
FLDIGELM_02745 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDIGELM_02746 0.0 3.2.1.132 M Putative peptidoglycan binding domain
FLDIGELM_02747 1.7e-93 M Peptidoglycan-binding domain 1 protein
FLDIGELM_02749 5.2e-234 ykuI T Diguanylate phosphodiesterase
FLDIGELM_02750 3.9e-37 ykuJ S protein conserved in bacteria
FLDIGELM_02751 4.4e-94 ykuK S Ribonuclease H-like
FLDIGELM_02752 3.9e-27 ykzF S Antirepressor AbbA
FLDIGELM_02753 1.6e-76 ykuL S CBS domain
FLDIGELM_02754 3.5e-168 ccpC K Transcriptional regulator
FLDIGELM_02755 5.7e-88 fld C Flavodoxin domain
FLDIGELM_02756 3.2e-177 ykuO
FLDIGELM_02757 3.2e-80 fld C Flavodoxin
FLDIGELM_02758 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
FLDIGELM_02759 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
FLDIGELM_02760 9e-37 ykuS S Belongs to the UPF0180 family
FLDIGELM_02761 8.8e-142 ykuT M Mechanosensitive ion channel
FLDIGELM_02762 3.9e-101 ykuU O Alkyl hydroperoxide reductase
FLDIGELM_02763 4.4e-82 ykuV CO thiol-disulfide
FLDIGELM_02764 5.8e-95 rok K Repressor of ComK
FLDIGELM_02765 2.9e-147 yknT
FLDIGELM_02766 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
FLDIGELM_02767 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
FLDIGELM_02768 8.1e-246 moeA 2.10.1.1 H molybdopterin
FLDIGELM_02769 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
FLDIGELM_02770 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
FLDIGELM_02771 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FLDIGELM_02772 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
FLDIGELM_02773 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
FLDIGELM_02774 1e-117 yknW S Yip1 domain
FLDIGELM_02775 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FLDIGELM_02776 2.5e-124 macB V ABC transporter, ATP-binding protein
FLDIGELM_02777 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
FLDIGELM_02778 3.1e-136 fruR K Transcriptional regulator
FLDIGELM_02779 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
FLDIGELM_02780 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
FLDIGELM_02781 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
FLDIGELM_02782 8.1e-39 ykoA
FLDIGELM_02783 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FLDIGELM_02784 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLDIGELM_02785 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
FLDIGELM_02786 1.1e-12 S Uncharacterized protein YkpC
FLDIGELM_02787 7.7e-183 mreB D Rod-share determining protein MreBH
FLDIGELM_02788 1.5e-43 abrB K of stationary sporulation gene expression
FLDIGELM_02789 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
FLDIGELM_02790 1.4e-153 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
FLDIGELM_02791 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
FLDIGELM_02792 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FLDIGELM_02793 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLDIGELM_02794 8.2e-31 ykzG S Belongs to the UPF0356 family
FLDIGELM_02795 5.5e-147 ykrA S hydrolases of the HAD superfamily
FLDIGELM_02796 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FLDIGELM_02798 4.6e-109 recN L Putative cell-wall binding lipoprotein
FLDIGELM_02799 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FLDIGELM_02800 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FLDIGELM_02801 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FLDIGELM_02802 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FLDIGELM_02803 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
FLDIGELM_02804 3.5e-277 speA 4.1.1.19 E Arginine
FLDIGELM_02805 1.6e-42 yktA S Belongs to the UPF0223 family
FLDIGELM_02806 7.1e-118 yktB S Belongs to the UPF0637 family
FLDIGELM_02807 7.1e-26 ykzI
FLDIGELM_02808 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
FLDIGELM_02809 6.9e-78 ykzC S Acetyltransferase (GNAT) family
FLDIGELM_02810 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FLDIGELM_02811 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
FLDIGELM_02812 0.0 ylaA
FLDIGELM_02813 2.7e-42 ylaB
FLDIGELM_02814 8e-39 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
FLDIGELM_02815 5.9e-11 sigC S Putative zinc-finger
FLDIGELM_02816 1.8e-38 ylaE
FLDIGELM_02817 8.2e-22 S Family of unknown function (DUF5325)
FLDIGELM_02818 0.0 typA T GTP-binding protein TypA
FLDIGELM_02819 4.2e-47 ylaH S YlaH-like protein
FLDIGELM_02820 2.5e-32 ylaI S protein conserved in bacteria
FLDIGELM_02821 5.2e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
FLDIGELM_02822 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
FLDIGELM_02823 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FLDIGELM_02824 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
FLDIGELM_02825 8.7e-44 ylaN S Belongs to the UPF0358 family
FLDIGELM_02826 4.5e-214 ftsW D Belongs to the SEDS family
FLDIGELM_02827 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FLDIGELM_02828 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
FLDIGELM_02829 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
FLDIGELM_02830 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
FLDIGELM_02831 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FLDIGELM_02832 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
FLDIGELM_02833 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
FLDIGELM_02834 3e-167 ctaG S cytochrome c oxidase
FLDIGELM_02835 7e-62 ylbA S YugN-like family
FLDIGELM_02836 2.6e-74 ylbB T COG0517 FOG CBS domain
FLDIGELM_02837 3e-201 ylbC S protein with SCP PR1 domains
FLDIGELM_02838 4.1e-63 ylbD S Putative coat protein
FLDIGELM_02839 6.7e-37 ylbE S YlbE-like protein
FLDIGELM_02840 1.8e-75 ylbF S Belongs to the UPF0342 family
FLDIGELM_02841 7.5e-39 ylbG S UPF0298 protein
FLDIGELM_02842 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
FLDIGELM_02843 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FLDIGELM_02844 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
FLDIGELM_02845 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
FLDIGELM_02846 6.8e-187 ylbL T Belongs to the peptidase S16 family
FLDIGELM_02847 2.8e-235 ylbM S Belongs to the UPF0348 family
FLDIGELM_02849 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
FLDIGELM_02850 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
FLDIGELM_02851 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
FLDIGELM_02852 4e-89 ylbP K n-acetyltransferase
FLDIGELM_02853 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FLDIGELM_02854 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
FLDIGELM_02855 2.9e-78 mraZ K Belongs to the MraZ family
FLDIGELM_02856 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FLDIGELM_02857 3.7e-44 ftsL D Essential cell division protein
FLDIGELM_02858 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
FLDIGELM_02859 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
FLDIGELM_02860 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FLDIGELM_02861 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FLDIGELM_02862 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FLDIGELM_02863 5.7e-186 spoVE D Belongs to the SEDS family
FLDIGELM_02864 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FLDIGELM_02865 5.3e-167 murB 1.3.1.98 M cell wall formation
FLDIGELM_02866 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
FLDIGELM_02867 2.4e-103 ylxW S protein conserved in bacteria
FLDIGELM_02868 5.1e-102 ylxX S protein conserved in bacteria
FLDIGELM_02869 6.2e-58 sbp S small basic protein
FLDIGELM_02870 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FLDIGELM_02871 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FLDIGELM_02872 0.0 bpr O COG1404 Subtilisin-like serine proteases
FLDIGELM_02873 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
FLDIGELM_02874 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLDIGELM_02875 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLDIGELM_02876 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
FLDIGELM_02877 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
FLDIGELM_02878 2.4e-37 ylmC S sporulation protein
FLDIGELM_02879 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
FLDIGELM_02880 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FLDIGELM_02881 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
FLDIGELM_02882 1.3e-39 yggT S membrane
FLDIGELM_02883 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
FLDIGELM_02884 2.6e-67 divIVA D Cell division initiation protein
FLDIGELM_02885 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FLDIGELM_02886 1.3e-63 dksA T COG1734 DnaK suppressor protein
FLDIGELM_02887 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FLDIGELM_02888 5.5e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
FLDIGELM_02889 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FLDIGELM_02890 6.4e-230 pyrP F Xanthine uracil
FLDIGELM_02891 1.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
FLDIGELM_02892 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
FLDIGELM_02893 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
FLDIGELM_02894 0.0 carB 6.3.5.5 F Belongs to the CarB family
FLDIGELM_02895 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
FLDIGELM_02896 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FLDIGELM_02897 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
FLDIGELM_02898 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FLDIGELM_02900 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
FLDIGELM_02901 1.1e-179 cysP P phosphate transporter
FLDIGELM_02902 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
FLDIGELM_02903 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
FLDIGELM_02904 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
FLDIGELM_02905 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
FLDIGELM_02906 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
FLDIGELM_02907 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
FLDIGELM_02908 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
FLDIGELM_02909 2.4e-156 yloC S stress-induced protein
FLDIGELM_02910 1.5e-40 ylzA S Belongs to the UPF0296 family
FLDIGELM_02911 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
FLDIGELM_02912 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
FLDIGELM_02913 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FLDIGELM_02914 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLDIGELM_02915 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FLDIGELM_02916 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FLDIGELM_02917 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FLDIGELM_02918 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FLDIGELM_02919 2.4e-141 stp 3.1.3.16 T phosphatase
FLDIGELM_02920 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
FLDIGELM_02921 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FLDIGELM_02922 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
FLDIGELM_02923 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
FLDIGELM_02924 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
FLDIGELM_02925 5.5e-59 asp S protein conserved in bacteria
FLDIGELM_02926 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
FLDIGELM_02927 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
FLDIGELM_02928 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
FLDIGELM_02929 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FLDIGELM_02930 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
FLDIGELM_02931 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FLDIGELM_02932 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
FLDIGELM_02933 6.1e-129 IQ reductase
FLDIGELM_02934 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
FLDIGELM_02935 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FLDIGELM_02936 0.0 smc D Required for chromosome condensation and partitioning
FLDIGELM_02937 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FLDIGELM_02938 2.9e-87
FLDIGELM_02939 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FLDIGELM_02940 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FLDIGELM_02941 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
FLDIGELM_02942 1.2e-36 ylqC S Belongs to the UPF0109 family
FLDIGELM_02943 1.3e-61 ylqD S YlqD protein
FLDIGELM_02944 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FLDIGELM_02945 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
FLDIGELM_02946 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FLDIGELM_02947 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FLDIGELM_02948 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FLDIGELM_02949 8.5e-291 ylqG
FLDIGELM_02950 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
FLDIGELM_02951 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
FLDIGELM_02952 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FLDIGELM_02953 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
FLDIGELM_02954 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLDIGELM_02955 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FLDIGELM_02956 2.5e-169 xerC L tyrosine recombinase XerC
FLDIGELM_02957 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FLDIGELM_02958 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FLDIGELM_02959 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FLDIGELM_02960 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
FLDIGELM_02961 2.6e-74 flgC N Belongs to the flagella basal body rod proteins family
FLDIGELM_02962 1.9e-31 fliE N Flagellar hook-basal body
FLDIGELM_02963 2.4e-255 fliF N The M ring may be actively involved in energy transduction
FLDIGELM_02964 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
FLDIGELM_02965 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
FLDIGELM_02966 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
FLDIGELM_02967 1.5e-69 fliJ N Flagellar biosynthesis chaperone
FLDIGELM_02968 7.7e-37 ylxF S MgtE intracellular N domain
FLDIGELM_02969 1.2e-221 fliK N Flagellar hook-length control protein
FLDIGELM_02970 1.7e-72 flgD N Flagellar basal body rod modification protein
FLDIGELM_02971 8.2e-140 flgG N Flagellar basal body rod
FLDIGELM_02972 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
FLDIGELM_02973 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
FLDIGELM_02974 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FLDIGELM_02975 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
FLDIGELM_02976 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
FLDIGELM_02977 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
FLDIGELM_02978 2.2e-36 fliQ N Role in flagellar biosynthesis
FLDIGELM_02979 3.6e-132 fliR N Flagellar biosynthetic protein FliR
FLDIGELM_02980 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLDIGELM_02981 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FLDIGELM_02982 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
FLDIGELM_02983 7.5e-158 flhG D Belongs to the ParA family
FLDIGELM_02984 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
FLDIGELM_02985 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
FLDIGELM_02986 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
FLDIGELM_02987 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
FLDIGELM_02988 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
FLDIGELM_02989 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLDIGELM_02990 4.3e-78 ylxL
FLDIGELM_02991 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
FLDIGELM_02992 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FLDIGELM_02993 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
FLDIGELM_02994 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FLDIGELM_02995 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FLDIGELM_02996 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
FLDIGELM_02997 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
FLDIGELM_02998 7.7e-233 rasP M zinc metalloprotease
FLDIGELM_02999 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
FLDIGELM_03000 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FLDIGELM_03001 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
FLDIGELM_03002 1.1e-203 nusA K Participates in both transcription termination and antitermination
FLDIGELM_03003 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
FLDIGELM_03004 3.1e-47 ylxQ J ribosomal protein
FLDIGELM_03005 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FLDIGELM_03006 3e-44 ylxP S protein conserved in bacteria
FLDIGELM_03007 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FLDIGELM_03008 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FLDIGELM_03009 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
FLDIGELM_03010 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FLDIGELM_03011 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
FLDIGELM_03012 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
FLDIGELM_03013 4.4e-233 pepR S Belongs to the peptidase M16 family
FLDIGELM_03014 2.6e-42 ymxH S YlmC YmxH family
FLDIGELM_03015 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
FLDIGELM_03016 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
FLDIGELM_03017 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FLDIGELM_03018 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
FLDIGELM_03019 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FLDIGELM_03020 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FLDIGELM_03021 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
FLDIGELM_03022 4.4e-32 S YlzJ-like protein
FLDIGELM_03023 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
FLDIGELM_03024 1.4e-133 ymfC K Transcriptional regulator
FLDIGELM_03025 1.5e-206 ymfD EGP Major facilitator Superfamily
FLDIGELM_03026 2.9e-235 ymfF S Peptidase M16
FLDIGELM_03027 1.4e-242 ymfH S zinc protease
FLDIGELM_03028 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
FLDIGELM_03029 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
FLDIGELM_03030 2.7e-143 ymfK S Protein of unknown function (DUF3388)
FLDIGELM_03031 1.9e-124 ymfM S protein conserved in bacteria
FLDIGELM_03032 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FLDIGELM_03033 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
FLDIGELM_03034 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FLDIGELM_03035 1e-215 pbpX V Beta-lactamase
FLDIGELM_03036 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
FLDIGELM_03037 1.9e-152 ymdB S protein conserved in bacteria
FLDIGELM_03038 1.2e-36 spoVS S Stage V sporulation protein S
FLDIGELM_03039 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
FLDIGELM_03040 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
FLDIGELM_03041 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FLDIGELM_03042 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
FLDIGELM_03043 2.2e-88 cotE S Spore coat protein
FLDIGELM_03044 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FLDIGELM_03045 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FLDIGELM_03046 2.3e-70 S Regulatory protein YrvL
FLDIGELM_03048 1.2e-97 ymcC S Membrane
FLDIGELM_03049 4.4e-109 pksA K Transcriptional regulator
FLDIGELM_03050 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
FLDIGELM_03051 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
FLDIGELM_03053 2.4e-186 pksD Q Acyl transferase domain
FLDIGELM_03054 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
FLDIGELM_03055 1.4e-37 acpK IQ Phosphopantetheine attachment site
FLDIGELM_03056 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FLDIGELM_03057 1.3e-245 pksG 2.3.3.10 I synthase
FLDIGELM_03058 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
FLDIGELM_03059 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
FLDIGELM_03060 0.0 rhiB IQ polyketide synthase
FLDIGELM_03061 0.0 pfaA Q Polyketide synthase of type I
FLDIGELM_03062 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
FLDIGELM_03063 0.0 dhbF IQ polyketide synthase
FLDIGELM_03064 0.0 pks13 HQ Beta-ketoacyl synthase
FLDIGELM_03065 1.4e-231 cypA C Cytochrome P450
FLDIGELM_03066 4.4e-61 ymzB
FLDIGELM_03067 8.9e-161 ymaE S Metallo-beta-lactamase superfamily
FLDIGELM_03068 1.5e-250 aprX O Belongs to the peptidase S8 family
FLDIGELM_03069 1.9e-07 K Transcriptional regulator
FLDIGELM_03070 2.1e-126 ymaC S Replication protein
FLDIGELM_03071 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
FLDIGELM_03072 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
FLDIGELM_03073 5.4e-50 ebrA P Small Multidrug Resistance protein
FLDIGELM_03075 2.1e-46 ymaF S YmaF family
FLDIGELM_03076 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FLDIGELM_03077 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
FLDIGELM_03078 8.2e-23
FLDIGELM_03079 4.5e-22 ymzA
FLDIGELM_03080 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
FLDIGELM_03081 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLDIGELM_03082 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FLDIGELM_03083 2e-109 ymaB
FLDIGELM_03084 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FLDIGELM_03085 1.7e-176 spoVK O stage V sporulation protein K
FLDIGELM_03086 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FLDIGELM_03087 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
FLDIGELM_03088 1.1e-68 glnR K transcriptional
FLDIGELM_03089 7e-261 glnA 6.3.1.2 E glutamine synthetase
FLDIGELM_03090 5e-10
FLDIGELM_03091 2.5e-32
FLDIGELM_03092 5.8e-39
FLDIGELM_03093 6.8e-80 G regulation of fungal-type cell wall biogenesis
FLDIGELM_03094 4.9e-145 ynaC
FLDIGELM_03095 2e-99 ynaD J Acetyltransferase (GNAT) domain
FLDIGELM_03096 1.9e-123 ynaE S Domain of unknown function (DUF3885)
FLDIGELM_03097 6.4e-60 ynaF
FLDIGELM_03100 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
FLDIGELM_03101 3.9e-254 xynT G MFS/sugar transport protein
FLDIGELM_03102 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
FLDIGELM_03103 1.1e-212 xylR GK ROK family
FLDIGELM_03104 2.7e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
FLDIGELM_03105 4.8e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
FLDIGELM_03106 4.9e-111 yokF 3.1.31.1 L RNA catabolic process
FLDIGELM_03107 6.8e-254 iolT EGP Major facilitator Superfamily
FLDIGELM_03108 1.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLDIGELM_03109 5e-81 yncE S Protein of unknown function (DUF2691)
FLDIGELM_03110 5.3e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
FLDIGELM_03111 5.2e-15
FLDIGELM_03114 9.5e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FLDIGELM_03116 1.3e-134 S Domain of unknown function, YrpD
FLDIGELM_03119 7.9e-25 tatA U protein secretion
FLDIGELM_03120 1.8e-71
FLDIGELM_03121 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
FLDIGELM_03124 7.4e-286 gerAA EG Spore germination protein
FLDIGELM_03125 4.5e-197 gerAB U Spore germination
FLDIGELM_03126 4.2e-220 gerLC S Spore germination protein
FLDIGELM_03127 7.7e-154 yndG S DoxX-like family
FLDIGELM_03128 2.6e-117 yndH S Domain of unknown function (DUF4166)
FLDIGELM_03129 0.0 yndJ S YndJ-like protein
FLDIGELM_03131 8.6e-139 yndL S Replication protein
FLDIGELM_03132 5.8e-74 yndM S Protein of unknown function (DUF2512)
FLDIGELM_03133 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
FLDIGELM_03135 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FLDIGELM_03136 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
FLDIGELM_03137 9.2e-113 yneB L resolvase
FLDIGELM_03138 1.3e-32 ynzC S UPF0291 protein
FLDIGELM_03139 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FLDIGELM_03140 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
FLDIGELM_03141 1.8e-28 yneF S UPF0154 protein
FLDIGELM_03142 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
FLDIGELM_03143 7.1e-127 ccdA O cytochrome c biogenesis protein
FLDIGELM_03144 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
FLDIGELM_03145 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
FLDIGELM_03146 4.2e-74 yneK S Protein of unknown function (DUF2621)
FLDIGELM_03147 4.1e-65 hspX O Spore coat protein
FLDIGELM_03148 3.9e-19 sspP S Belongs to the SspP family
FLDIGELM_03149 2.2e-14 sspO S Belongs to the SspO family
FLDIGELM_03150 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FLDIGELM_03151 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FLDIGELM_03153 3.1e-08 sspN S Small acid-soluble spore protein N family
FLDIGELM_03154 3.9e-35 tlp S Belongs to the Tlp family
FLDIGELM_03155 1.2e-73 yneP S Thioesterase-like superfamily
FLDIGELM_03156 1.3e-53 yneQ
FLDIGELM_03157 4.1e-49 yneR S Belongs to the HesB IscA family
FLDIGELM_03158 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FLDIGELM_03159 6.6e-69 yccU S CoA-binding protein
FLDIGELM_03160 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FLDIGELM_03161 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FLDIGELM_03162 2.3e-12
FLDIGELM_03163 1.3e-57 ynfC
FLDIGELM_03164 8.2e-252 agcS E Sodium alanine symporter
FLDIGELM_03165 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
FLDIGELM_03167 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
FLDIGELM_03168 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
FLDIGELM_03169 2.4e-80 yngA S membrane
FLDIGELM_03170 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
FLDIGELM_03171 5.5e-104 yngC S membrane-associated protein
FLDIGELM_03172 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
FLDIGELM_03173 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
FLDIGELM_03174 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
FLDIGELM_03175 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
FLDIGELM_03176 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
FLDIGELM_03177 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
FLDIGELM_03178 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
FLDIGELM_03179 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
FLDIGELM_03180 1.8e-31 S Family of unknown function (DUF5367)
FLDIGELM_03181 1.3e-306 yngK T Glycosyl hydrolase-like 10
FLDIGELM_03182 2.8e-64 yngL S Protein of unknown function (DUF1360)
FLDIGELM_03183 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
FLDIGELM_03184 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDIGELM_03185 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDIGELM_03186 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
FLDIGELM_03188 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
FLDIGELM_03189 2.2e-142 ybbA S Putative esterase
FLDIGELM_03190 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_03191 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_03192 7.2e-167 feuA P Iron-uptake system-binding protein
FLDIGELM_03193 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
FLDIGELM_03194 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
FLDIGELM_03195 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
FLDIGELM_03196 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
FLDIGELM_03197 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FLDIGELM_03198 1.1e-150 ybbH K transcriptional
FLDIGELM_03199 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FLDIGELM_03200 6.4e-87 ybbJ J acetyltransferase
FLDIGELM_03201 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
FLDIGELM_03207 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
FLDIGELM_03208 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
FLDIGELM_03209 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FLDIGELM_03210 3e-225 ybbR S protein conserved in bacteria
FLDIGELM_03211 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FLDIGELM_03212 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
FLDIGELM_03213 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FLDIGELM_03214 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
FLDIGELM_03215 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FLDIGELM_03216 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
FLDIGELM_03217 0.0 ybcC S Belongs to the UPF0753 family
FLDIGELM_03218 3.7e-96 can 4.2.1.1 P carbonic anhydrase
FLDIGELM_03219 3.9e-47
FLDIGELM_03220 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
FLDIGELM_03221 5.1e-50 ybzH K Helix-turn-helix domain
FLDIGELM_03222 2.6e-203 ybcL EGP Major facilitator Superfamily
FLDIGELM_03224 9.1e-239 J 4Fe-4S single cluster domain
FLDIGELM_03225 1.6e-277 V CAAX protease self-immunity
FLDIGELM_03226 1.9e-135 skfE V ABC transporter
FLDIGELM_03227 4e-248 skfF S ABC transporter
FLDIGELM_03228 7.8e-91 C HEAT repeats
FLDIGELM_03229 9.6e-79 txn CO Thioredoxin-like
FLDIGELM_03230 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
FLDIGELM_03231 1.5e-123 T Transcriptional regulatory protein, C terminal
FLDIGELM_03232 1.8e-173 T His Kinase A (phospho-acceptor) domain
FLDIGELM_03234 1.6e-140 KLT Protein tyrosine kinase
FLDIGELM_03235 4.8e-154 ybdN
FLDIGELM_03236 1.5e-217 ybdO S Domain of unknown function (DUF4885)
FLDIGELM_03237 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
FLDIGELM_03238 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
FLDIGELM_03239 4.9e-30 ybxH S Family of unknown function (DUF5370)
FLDIGELM_03240 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
FLDIGELM_03241 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
FLDIGELM_03242 4.9e-41 ybyB
FLDIGELM_03243 8.8e-290 ybeC E amino acid
FLDIGELM_03244 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
FLDIGELM_03245 7.3e-258 glpT G -transporter
FLDIGELM_03246 2.9e-35 S Protein of unknown function (DUF2651)
FLDIGELM_03247 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
FLDIGELM_03248 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
FLDIGELM_03250 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
FLDIGELM_03251 8.8e-162 ybfH EG EamA-like transporter family
FLDIGELM_03252 9.7e-144 msmR K AraC-like ligand binding domain
FLDIGELM_03253 2.3e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FLDIGELM_03254 1.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
FLDIGELM_03256 2.1e-168 S Alpha/beta hydrolase family
FLDIGELM_03257 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FLDIGELM_03258 2.7e-85 ybfM S SNARE associated Golgi protein
FLDIGELM_03259 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
FLDIGELM_03260 4.6e-45 ybfN
FLDIGELM_03261 3.2e-253 S Erythromycin esterase
FLDIGELM_03262 6.7e-167 ybfP K Transcriptional regulator
FLDIGELM_03263 3.9e-192 yceA S Belongs to the UPF0176 family
FLDIGELM_03264 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FLDIGELM_03265 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FLDIGELM_03266 4.8e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
FLDIGELM_03267 4.9e-128 K UTRA
FLDIGELM_03269 8.6e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
FLDIGELM_03270 4.1e-259 mmuP E amino acid
FLDIGELM_03271 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
FLDIGELM_03272 5.6e-256 agcS E Sodium alanine symporter
FLDIGELM_03273 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
FLDIGELM_03274 2.1e-228 phoQ 2.7.13.3 T Histidine kinase
FLDIGELM_03275 9e-170 glnL T Regulator
FLDIGELM_03276 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
FLDIGELM_03277 6.9e-273 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FLDIGELM_03278 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
FLDIGELM_03279 3.6e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
FLDIGELM_03280 1.5e-124 ycbG K FCD
FLDIGELM_03281 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
FLDIGELM_03282 3.1e-175 ycbJ S Macrolide 2'-phosphotransferase
FLDIGELM_03283 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
FLDIGELM_03284 7.3e-172 eamA1 EG spore germination
FLDIGELM_03285 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_03286 7.6e-169 T PhoQ Sensor
FLDIGELM_03287 4.8e-168 ycbN V ABC transporter, ATP-binding protein
FLDIGELM_03288 2.1e-115 S ABC-2 family transporter protein
FLDIGELM_03289 8.2e-53 ycbP S Protein of unknown function (DUF2512)
FLDIGELM_03290 1.3e-78 sleB 3.5.1.28 M Cell wall
FLDIGELM_03291 6.6e-136 ycbR T vWA found in TerF C terminus
FLDIGELM_03292 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
FLDIGELM_03293 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
FLDIGELM_03294 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLDIGELM_03295 1.3e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FLDIGELM_03296 2.7e-205 ycbU E Selenocysteine lyase
FLDIGELM_03297 3e-225 lmrB EGP the major facilitator superfamily
FLDIGELM_03298 6.3e-102 yxaF K Transcriptional regulator
FLDIGELM_03299 2.6e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
FLDIGELM_03300 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
FLDIGELM_03301 7.1e-57 S RDD family
FLDIGELM_03302 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
FLDIGELM_03303 1.1e-159 2.7.13.3 T GHKL domain
FLDIGELM_03304 1.2e-126 lytR_2 T LytTr DNA-binding domain
FLDIGELM_03305 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
FLDIGELM_03306 2.2e-202 natB CP ABC-2 family transporter protein
FLDIGELM_03307 1.7e-173 yccK C Aldo keto reductase
FLDIGELM_03308 6.6e-177 ycdA S Domain of unknown function (DUF5105)
FLDIGELM_03309 8.3e-276 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
FLDIGELM_03310 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
FLDIGELM_03311 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
FLDIGELM_03312 5.5e-174 S response regulator aspartate phosphatase
FLDIGELM_03313 4.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
FLDIGELM_03314 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
FLDIGELM_03315 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
FLDIGELM_03316 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
FLDIGELM_03317 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
FLDIGELM_03318 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLDIGELM_03319 1.1e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
FLDIGELM_03320 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
FLDIGELM_03321 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
FLDIGELM_03322 1.4e-136 terC P Protein of unknown function (DUF475)
FLDIGELM_03323 0.0 yceG S Putative component of 'biosynthetic module'
FLDIGELM_03324 2e-192 yceH P Belongs to the TelA family
FLDIGELM_03325 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
FLDIGELM_03326 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
FLDIGELM_03327 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
FLDIGELM_03328 5.1e-229 proV 3.6.3.32 E glycine betaine
FLDIGELM_03329 1.3e-127 opuAB P glycine betaine
FLDIGELM_03330 1.5e-163 opuAC E glycine betaine
FLDIGELM_03331 1.1e-217 amhX S amidohydrolase
FLDIGELM_03332 8.7e-257 ycgA S Membrane
FLDIGELM_03333 4.1e-81 ycgB
FLDIGELM_03334 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
FLDIGELM_03335 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
FLDIGELM_03336 3.9e-290 lctP C L-lactate permease
FLDIGELM_03337 3.9e-263 mdr EGP Major facilitator Superfamily
FLDIGELM_03338 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
FLDIGELM_03339 6.8e-113 ycgF E Lysine exporter protein LysE YggA
FLDIGELM_03340 1.3e-150 yqcI S YqcI/YcgG family
FLDIGELM_03341 1.1e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
FLDIGELM_03342 2.4e-112 ycgI S Domain of unknown function (DUF1989)
FLDIGELM_03343 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
FLDIGELM_03344 2.1e-108 tmrB S AAA domain
FLDIGELM_03346 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FLDIGELM_03347 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
FLDIGELM_03348 2.2e-179 oxyR3 K LysR substrate binding domain
FLDIGELM_03349 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
FLDIGELM_03350 2.9e-145 ycgL S Predicted nucleotidyltransferase
FLDIGELM_03351 5.1e-170 ycgM E Proline dehydrogenase
FLDIGELM_03352 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
FLDIGELM_03353 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLDIGELM_03354 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
FLDIGELM_03355 2.6e-147 ycgQ S membrane
FLDIGELM_03356 1.2e-139 ycgR S permeases
FLDIGELM_03357 5.7e-163 I alpha/beta hydrolase fold
FLDIGELM_03358 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
FLDIGELM_03359 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
FLDIGELM_03360 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
FLDIGELM_03361 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FLDIGELM_03362 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FLDIGELM_03363 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
FLDIGELM_03364 3.8e-221 nasA P COG2223 Nitrate nitrite transporter
FLDIGELM_03365 5.7e-169 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
FLDIGELM_03366 9.4e-101 yciB M ErfK YbiS YcfS YnhG
FLDIGELM_03367 1.4e-228 yciC S GTPases (G3E family)
FLDIGELM_03368 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
FLDIGELM_03369 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
FLDIGELM_03371 3.5e-52 yckD S Protein of unknown function (DUF2680)
FLDIGELM_03372 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FLDIGELM_03373 3.4e-70 nin S Competence protein J (ComJ)
FLDIGELM_03374 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
FLDIGELM_03375 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
FLDIGELM_03376 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
FLDIGELM_03377 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
FLDIGELM_03378 1.3e-63 hxlR K transcriptional
FLDIGELM_03379 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDIGELM_03380 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDIGELM_03381 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
FLDIGELM_03382 5.7e-140 srfAD Q thioesterase
FLDIGELM_03383 1.5e-225 EGP Major Facilitator Superfamily
FLDIGELM_03384 1.2e-84 S YcxB-like protein
FLDIGELM_03385 1.3e-160 ycxC EG EamA-like transporter family
FLDIGELM_03386 4.4e-247 ycxD K GntR family transcriptional regulator
FLDIGELM_03387 2.9e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
FLDIGELM_03388 4.4e-115 yczE S membrane
FLDIGELM_03389 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
FLDIGELM_03390 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
FLDIGELM_03391 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
FLDIGELM_03392 4.9e-162 bsdA K LysR substrate binding domain
FLDIGELM_03393 4.1e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
FLDIGELM_03394 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
FLDIGELM_03395 4e-39 bsdD 4.1.1.61 S response to toxic substance
FLDIGELM_03396 3.6e-79 yclD
FLDIGELM_03397 5.1e-156 yclE 3.4.11.5 S Alpha beta hydrolase
FLDIGELM_03398 9.2e-262 dtpT E amino acid peptide transporter
FLDIGELM_03399 7e-309 yclG M Pectate lyase superfamily protein
FLDIGELM_03401 6.8e-282 gerKA EG Spore germination protein
FLDIGELM_03402 1.3e-232 gerKC S spore germination
FLDIGELM_03403 9.9e-200 gerKB F Spore germination protein
FLDIGELM_03404 3.9e-122 yclH P ABC transporter
FLDIGELM_03405 1.7e-204 yclI V ABC transporter (permease) YclI
FLDIGELM_03406 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
FLDIGELM_03407 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
FLDIGELM_03408 5.2e-71 S aspartate phosphatase
FLDIGELM_03412 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
FLDIGELM_03413 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_03414 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_03415 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
FLDIGELM_03416 2.1e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
FLDIGELM_03417 4.1e-251 ycnB EGP Major facilitator Superfamily
FLDIGELM_03418 7.9e-152 ycnC K Transcriptional regulator
FLDIGELM_03419 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
FLDIGELM_03420 1.6e-45 ycnE S Monooxygenase
FLDIGELM_03421 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
FLDIGELM_03422 1.5e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FLDIGELM_03423 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FLDIGELM_03424 3.8e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FLDIGELM_03425 6.1e-149 glcU U Glucose uptake
FLDIGELM_03426 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDIGELM_03427 1.4e-99 ycnI S protein conserved in bacteria
FLDIGELM_03428 9.3e-308 ycnJ P protein, homolog of Cu resistance protein CopC
FLDIGELM_03429 2.8e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
FLDIGELM_03430 3.4e-53
FLDIGELM_03431 2.1e-239 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
FLDIGELM_03432 3.4e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
FLDIGELM_03433 1.8e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
FLDIGELM_03434 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
FLDIGELM_03435 2.5e-98 sipT 3.4.21.89 U Belongs to the peptidase S26 family
FLDIGELM_03436 1.4e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
FLDIGELM_03437 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
FLDIGELM_03439 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
FLDIGELM_03440 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
FLDIGELM_03441 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
FLDIGELM_03442 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
FLDIGELM_03443 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
FLDIGELM_03444 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
FLDIGELM_03445 1.2e-132 kipR K Transcriptional regulator
FLDIGELM_03446 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
FLDIGELM_03448 1.4e-49 yczJ S biosynthesis
FLDIGELM_03449 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
FLDIGELM_03450 2.8e-176 ydhF S Oxidoreductase
FLDIGELM_03451 0.0 mtlR K transcriptional regulator, MtlR
FLDIGELM_03452 1.4e-294 ydaB IQ acyl-CoA ligase
FLDIGELM_03453 1.1e-99 ydaC Q Methyltransferase domain
FLDIGELM_03454 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDIGELM_03455 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
FLDIGELM_03456 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
FLDIGELM_03457 6.8e-77 ydaG 1.4.3.5 S general stress protein
FLDIGELM_03458 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
FLDIGELM_03459 5.1e-47 ydzA EGP Major facilitator Superfamily
FLDIGELM_03460 2.5e-74 lrpC K Transcriptional regulator
FLDIGELM_03461 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FLDIGELM_03462 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
FLDIGELM_03463 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
FLDIGELM_03464 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
FLDIGELM_03465 4.5e-233 ydaM M Glycosyl transferase family group 2
FLDIGELM_03466 0.0 ydaN S Bacterial cellulose synthase subunit
FLDIGELM_03467 0.0 ydaO E amino acid
FLDIGELM_03468 8.5e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
FLDIGELM_03469 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
FLDIGELM_03470 9.4e-40
FLDIGELM_03471 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
FLDIGELM_03473 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
FLDIGELM_03474 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
FLDIGELM_03476 8.9e-59 ydbB G Cupin domain
FLDIGELM_03477 2.8e-63 ydbC S Domain of unknown function (DUF4937
FLDIGELM_03478 3.2e-155 ydbD P Catalase
FLDIGELM_03479 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
FLDIGELM_03480 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
FLDIGELM_03481 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
FLDIGELM_03482 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FLDIGELM_03483 4.4e-181 ydbI S AI-2E family transporter
FLDIGELM_03484 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
FLDIGELM_03485 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FLDIGELM_03486 2.7e-52 ydbL
FLDIGELM_03487 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
FLDIGELM_03488 1.1e-18 S Fur-regulated basic protein B
FLDIGELM_03489 2.2e-07 S Fur-regulated basic protein A
FLDIGELM_03490 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FLDIGELM_03491 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
FLDIGELM_03492 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
FLDIGELM_03493 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
FLDIGELM_03494 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
FLDIGELM_03495 2.1e-82 ydbS S Bacterial PH domain
FLDIGELM_03496 4.9e-263 ydbT S Membrane
FLDIGELM_03497 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
FLDIGELM_03498 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
FLDIGELM_03499 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
FLDIGELM_03500 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FLDIGELM_03501 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
FLDIGELM_03502 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
FLDIGELM_03503 1.3e-143 rsbR T Positive regulator of sigma-B
FLDIGELM_03504 5.2e-57 rsbS T antagonist
FLDIGELM_03505 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
FLDIGELM_03506 7.1e-189 rsbU 3.1.3.3 KT phosphatase
FLDIGELM_03507 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
FLDIGELM_03508 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
FLDIGELM_03509 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FLDIGELM_03510 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
FLDIGELM_03514 1.5e-82 ydcG S EVE domain
FLDIGELM_03515 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
FLDIGELM_03516 0.0 yhgF K COG2183 Transcriptional accessory protein
FLDIGELM_03517 1.6e-84 ydcK S Belongs to the SprT family
FLDIGELM_03525 2.7e-205 L Belongs to the 'phage' integrase family
FLDIGELM_03526 3.1e-84 immA E IrrE N-terminal-like domain
FLDIGELM_03527 1.4e-60 yvaO K Transcriptional
FLDIGELM_03528 3.1e-16
FLDIGELM_03530 3.7e-34 S Bacterial protein of unknown function (DUF961)
FLDIGELM_03532 8.7e-265 ydcQ D Ftsk spoiiie family protein
FLDIGELM_03533 2.5e-200 nicK L Replication initiation factor
FLDIGELM_03534 6.2e-17 S Domain of Unknown Function with PDB structure (DUF3850)
FLDIGELM_03537 4.9e-48 yddA
FLDIGELM_03538 2e-165 yddB S Conjugative transposon protein TcpC
FLDIGELM_03539 3e-40 yddC
FLDIGELM_03540 2.2e-93 yddD S TcpE family
FLDIGELM_03541 0.0 yddE S AAA-like domain
FLDIGELM_03542 7.5e-47 S Domain of unknown function (DUF1874)
FLDIGELM_03543 0.0 yddG S maturation of SSU-rRNA
FLDIGELM_03544 4.5e-188 yddH CBM50 M Lysozyme-like
FLDIGELM_03545 1.3e-82 yddI
FLDIGELM_03546 1.3e-55 S Domain of unknown function with cystatin-like fold (DUF4467)
FLDIGELM_03547 1.5e-73 S response regulator aspartate phosphatase
FLDIGELM_03549 1.1e-52
FLDIGELM_03550 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FLDIGELM_03551 2.4e-71 lrpA K transcriptional
FLDIGELM_03552 1.5e-77 lrpB K transcriptional
FLDIGELM_03553 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
FLDIGELM_03554 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
FLDIGELM_03555 5e-227 ydeG EGP Major facilitator Superfamily
FLDIGELM_03560 6.3e-75 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
FLDIGELM_03561 7.4e-24 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
FLDIGELM_03562 8.7e-30 cspL K Cold shock
FLDIGELM_03563 6.1e-79 carD K Transcription factor
FLDIGELM_03564 4.6e-35 ydzE EG spore germination
FLDIGELM_03565 1.1e-166 rhaS5 K AraC-like ligand binding domain
FLDIGELM_03566 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
FLDIGELM_03567 2.5e-166 ydeE K AraC family transcriptional regulator
FLDIGELM_03568 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FLDIGELM_03569 3.4e-220 ydeG EGP Major facilitator superfamily
FLDIGELM_03570 2.9e-47 ydeH
FLDIGELM_03571 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
FLDIGELM_03572 4e-116
FLDIGELM_03573 1.8e-153 ydeK EG -transporter
FLDIGELM_03574 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FLDIGELM_03575 4.2e-74 maoC I N-terminal half of MaoC dehydratase
FLDIGELM_03576 8.6e-107 ydeN S Serine hydrolase
FLDIGELM_03577 1.1e-58 K HxlR-like helix-turn-helix
FLDIGELM_03578 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
FLDIGELM_03579 4.8e-69 ydeP K Transcriptional regulator
FLDIGELM_03580 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
FLDIGELM_03581 1.2e-195 ydeR EGP Major facilitator Superfamily
FLDIGELM_03582 8.4e-105 ydeS K Transcriptional regulator
FLDIGELM_03583 1.3e-57 arsR K transcriptional
FLDIGELM_03584 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FLDIGELM_03585 7.2e-149 ydfB J GNAT acetyltransferase
FLDIGELM_03586 1.7e-157 ydfC EG EamA-like transporter family
FLDIGELM_03587 3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
FLDIGELM_03588 2.1e-114 ydfE S Flavin reductase like domain
FLDIGELM_03589 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
FLDIGELM_03590 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FLDIGELM_03592 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
FLDIGELM_03593 9.3e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
FLDIGELM_03594 0.0 ydfJ S drug exporters of the RND superfamily
FLDIGELM_03595 1.4e-175 S Alpha/beta hydrolase family
FLDIGELM_03596 8.2e-106 S Protein of unknown function (DUF554)
FLDIGELM_03597 9.2e-147 K Bacterial transcription activator, effector binding domain
FLDIGELM_03598 3.5e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FLDIGELM_03599 4.5e-109 ydfN C nitroreductase
FLDIGELM_03600 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
FLDIGELM_03601 8.8e-63 mhqP S DoxX
FLDIGELM_03602 1.3e-57 traF CO Thioredoxin
FLDIGELM_03604 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
FLDIGELM_03605 6.3e-29
FLDIGELM_03607 4.4e-118 ydfR S Protein of unknown function (DUF421)
FLDIGELM_03608 5.2e-122 ydfS S Protein of unknown function (DUF421)
FLDIGELM_03609 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
FLDIGELM_03610 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
FLDIGELM_03611 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
FLDIGELM_03612 1.5e-101 K Bacterial regulatory proteins, tetR family
FLDIGELM_03613 7.3e-53 S DoxX-like family
FLDIGELM_03614 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
FLDIGELM_03615 4.2e-308 expZ S ABC transporter
FLDIGELM_03616 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
FLDIGELM_03617 4.6e-91 dinB S DinB family
FLDIGELM_03618 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
FLDIGELM_03619 0.0 ydgH S drug exporters of the RND superfamily
FLDIGELM_03620 1e-113 drgA C nitroreductase
FLDIGELM_03621 1.1e-69 ydgJ K Winged helix DNA-binding domain
FLDIGELM_03622 2.5e-209 tcaB EGP Major facilitator Superfamily
FLDIGELM_03623 1.2e-121 ydhB S membrane transporter protein
FLDIGELM_03624 6.5e-122 ydhC K FCD
FLDIGELM_03625 3.3e-244 ydhD M Glycosyl hydrolase
FLDIGELM_03626 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
FLDIGELM_03627 1.9e-127
FLDIGELM_03628 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
FLDIGELM_03629 4.6e-69 frataxin S Domain of unknown function (DU1801)
FLDIGELM_03631 4.1e-86 K Acetyltransferase (GNAT) domain
FLDIGELM_03632 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
FLDIGELM_03633 1.7e-99 ydhK M Protein of unknown function (DUF1541)
FLDIGELM_03634 4.6e-200 pbuE EGP Major facilitator Superfamily
FLDIGELM_03635 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
FLDIGELM_03636 8.7e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
FLDIGELM_03637 1.6e-234 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FLDIGELM_03638 1.2e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
FLDIGELM_03639 3.9e-133 ydhQ K UTRA
FLDIGELM_03640 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
FLDIGELM_03641 1.8e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
FLDIGELM_03642 2.1e-215 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
FLDIGELM_03643 1e-156 ydhU P Catalase
FLDIGELM_03646 6.7e-167 ygxA S Nucleotidyltransferase-like
FLDIGELM_03647 1.5e-56 ygzB S UPF0295 protein
FLDIGELM_03648 4e-80 perR P Belongs to the Fur family
FLDIGELM_03649 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
FLDIGELM_03650 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
FLDIGELM_03651 8.7e-180 ygaE S Membrane
FLDIGELM_03652 1.8e-301 ygaD V ABC transporter
FLDIGELM_03653 1.3e-104 ygaC J Belongs to the UPF0374 family
FLDIGELM_03654 1.5e-37 ygaB S YgaB-like protein
FLDIGELM_03655 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
FLDIGELM_03656 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FLDIGELM_03657 6.9e-36 yfhS
FLDIGELM_03658 7.8e-212 mutY L A G-specific
FLDIGELM_03659 5.5e-186 yfhP S membrane-bound metal-dependent
FLDIGELM_03660 0.0 yfhO S Bacterial membrane protein YfhO
FLDIGELM_03661 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
FLDIGELM_03662 6.7e-172 yfhM S Alpha beta hydrolase
FLDIGELM_03663 3.5e-51 yfhL S SdpI/YhfL protein family
FLDIGELM_03664 9.2e-92 batE T Bacterial SH3 domain homologues
FLDIGELM_03665 1.3e-44 yfhJ S WVELL protein
FLDIGELM_03666 6.2e-20 sspK S reproduction
FLDIGELM_03667 1.1e-209 yfhI EGP Major facilitator Superfamily
FLDIGELM_03669 9.7e-52 yfhH S Protein of unknown function (DUF1811)
FLDIGELM_03670 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
FLDIGELM_03671 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
FLDIGELM_03673 2.1e-25 yfhD S YfhD-like protein
FLDIGELM_03674 3.9e-107 yfhC C nitroreductase
FLDIGELM_03675 1.8e-167 yfhB 5.3.3.17 S PhzF family
FLDIGELM_03676 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_03677 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_03678 6.2e-182 yfiY P ABC transporter substrate-binding protein
FLDIGELM_03679 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FLDIGELM_03680 3.1e-81 yfiV K transcriptional
FLDIGELM_03681 8.7e-287 yfiU EGP Major facilitator Superfamily
FLDIGELM_03682 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
FLDIGELM_03683 5.1e-221 yfiS EGP Major facilitator Superfamily
FLDIGELM_03684 2e-109 yfiR K Transcriptional regulator
FLDIGELM_03685 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
FLDIGELM_03686 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
FLDIGELM_03687 8.3e-99 padR K transcriptional
FLDIGELM_03688 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
FLDIGELM_03689 9.8e-214 V ABC-2 family transporter protein
FLDIGELM_03690 6.2e-171 V ABC transporter, ATP-binding protein
FLDIGELM_03691 3.2e-113 KT LuxR family transcriptional regulator
FLDIGELM_03692 1.1e-214 yxjM T Histidine kinase
FLDIGELM_03694 1.1e-233 S Oxidoreductase
FLDIGELM_03695 8.4e-184 G Xylose isomerase
FLDIGELM_03696 1.8e-262 iolT EGP Major facilitator Superfamily
FLDIGELM_03697 1.5e-177 K AraC-like ligand binding domain
FLDIGELM_03698 5.7e-163 yfiE 1.13.11.2 S glyoxalase
FLDIGELM_03699 9.8e-65 mhqP S DoxX
FLDIGELM_03700 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
FLDIGELM_03701 2.1e-310 yfiB3 V ABC transporter
FLDIGELM_03702 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FLDIGELM_03703 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
FLDIGELM_03704 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
FLDIGELM_03705 1.1e-44 yfjA S Belongs to the WXG100 family
FLDIGELM_03706 9.2e-191 yfjB
FLDIGELM_03707 4.1e-144 yfjC
FLDIGELM_03708 1.8e-101 yfjD S Family of unknown function (DUF5381)
FLDIGELM_03709 1.3e-80 S Family of unknown function (DUF5381)
FLDIGELM_03710 4e-56 yfjF S UPF0060 membrane protein
FLDIGELM_03711 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
FLDIGELM_03712 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
FLDIGELM_03713 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FLDIGELM_03714 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
FLDIGELM_03715 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
FLDIGELM_03716 3e-29 yfjL
FLDIGELM_03717 1.1e-83 yfjM S Psort location Cytoplasmic, score
FLDIGELM_03718 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLDIGELM_03719 1.6e-39 S YfzA-like protein
FLDIGELM_03720 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLDIGELM_03721 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FLDIGELM_03722 1.7e-184 corA P Mediates influx of magnesium ions
FLDIGELM_03723 1.8e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
FLDIGELM_03724 1.7e-153 pdaA G deacetylase
FLDIGELM_03725 1.1e-26 yfjT
FLDIGELM_03726 5.4e-222 yfkA S YfkB-like domain
FLDIGELM_03727 6.6e-148 yfkC M Mechanosensitive ion channel
FLDIGELM_03728 1.2e-146 yfkD S YfkD-like protein
FLDIGELM_03729 1.8e-182 cax P COG0387 Ca2 H antiporter
FLDIGELM_03730 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
FLDIGELM_03731 5e-08
FLDIGELM_03732 8.2e-143 yihY S Belongs to the UPF0761 family
FLDIGELM_03733 2.4e-50 yfkI S gas vesicle protein
FLDIGELM_03734 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FLDIGELM_03735 2.1e-29 yfkK S Belongs to the UPF0435 family
FLDIGELM_03736 8.9e-207 ydiM EGP Major facilitator Superfamily
FLDIGELM_03737 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
FLDIGELM_03738 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
FLDIGELM_03739 1.1e-124 yfkO C nitroreductase
FLDIGELM_03740 1.8e-133 treR K transcriptional
FLDIGELM_03741 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
FLDIGELM_03742 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
FLDIGELM_03743 1.5e-283 yfkQ EG Spore germination protein
FLDIGELM_03744 5.1e-207 yfkR S spore germination
FLDIGELM_03746 1.6e-194 E Spore germination protein
FLDIGELM_03747 3.2e-256 agcS_1 E Sodium alanine symporter
FLDIGELM_03748 6e-67 yhdN S Domain of unknown function (DUF1992)
FLDIGELM_03749 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FLDIGELM_03750 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
FLDIGELM_03751 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
FLDIGELM_03752 2.4e-50 yflH S Protein of unknown function (DUF3243)
FLDIGELM_03753 4.1e-19 yflI
FLDIGELM_03754 4e-18 yflJ S Protein of unknown function (DUF2639)
FLDIGELM_03755 9e-124 yflK S protein conserved in bacteria
FLDIGELM_03756 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
FLDIGELM_03757 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
FLDIGELM_03758 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
FLDIGELM_03759 1.9e-226 citM C Citrate transporter
FLDIGELM_03760 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
FLDIGELM_03761 8.9e-119 citT T response regulator
FLDIGELM_03762 5.3e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
FLDIGELM_03763 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
FLDIGELM_03764 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
FLDIGELM_03765 7.6e-58 yflT S Heat induced stress protein YflT
FLDIGELM_03766 2.9e-24 S Protein of unknown function (DUF3212)
FLDIGELM_03767 1.7e-168 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
FLDIGELM_03768 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_03769 2e-167 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FLDIGELM_03770 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
FLDIGELM_03771 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
FLDIGELM_03772 2.2e-213 G Major Facilitator Superfamily
FLDIGELM_03773 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
FLDIGELM_03774 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
FLDIGELM_03775 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
FLDIGELM_03776 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FLDIGELM_03777 1.5e-209 yfmO EGP Major facilitator Superfamily
FLDIGELM_03778 1.4e-69 yfmP K transcriptional
FLDIGELM_03779 1.7e-73 yfmQ S Uncharacterised protein from bacillus cereus group
FLDIGELM_03780 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
FLDIGELM_03781 1.1e-113 yfmS NT chemotaxis protein
FLDIGELM_03782 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
FLDIGELM_03783 8.4e-241 yfnA E amino acid
FLDIGELM_03784 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
FLDIGELM_03785 1.9e-142 fsr P COG0477 Permeases of the major facilitator superfamily
FLDIGELM_03786 6.6e-45 fsr P COG0477 Permeases of the major facilitator superfamily
FLDIGELM_03787 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
FLDIGELM_03788 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
FLDIGELM_03789 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
FLDIGELM_03790 1.9e-172 yfnG 4.2.1.45 M dehydratase
FLDIGELM_03791 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
FLDIGELM_03792 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
FLDIGELM_03793 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
FLDIGELM_03794 3.6e-199 yetN S Protein of unknown function (DUF3900)
FLDIGELM_03795 2.2e-207 yetM CH FAD binding domain
FLDIGELM_03796 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
FLDIGELM_03797 5.4e-159 yetK EG EamA-like transporter family
FLDIGELM_03798 5.3e-105 yetJ S Belongs to the BI1 family
FLDIGELM_03799 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
FLDIGELM_03800 7.1e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
FLDIGELM_03801 2.2e-34
FLDIGELM_03802 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FLDIGELM_03803 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
FLDIGELM_03804 8.8e-122 yetF S membrane
FLDIGELM_03805 2.4e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
FLDIGELM_03806 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
FLDIGELM_03807 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
FLDIGELM_03808 9.6e-291 lplA G Bacterial extracellular solute-binding protein
FLDIGELM_03809 0.0 yetA
FLDIGELM_03810 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
FLDIGELM_03811 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
FLDIGELM_03813 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
FLDIGELM_03814 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
FLDIGELM_03815 9.7e-112 yesV S Protein of unknown function, DUF624
FLDIGELM_03816 6e-128 yesU S Domain of unknown function (DUF1961)
FLDIGELM_03817 1.3e-128 E GDSL-like Lipase/Acylhydrolase
FLDIGELM_03818 0.0 yesS K Transcriptional regulator
FLDIGELM_03819 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
FLDIGELM_03820 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
FLDIGELM_03821 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
FLDIGELM_03822 8e-246 yesO G Bacterial extracellular solute-binding protein
FLDIGELM_03823 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
FLDIGELM_03824 0.0 yesM 2.7.13.3 T Histidine kinase
FLDIGELM_03825 9.2e-102 yesL S Protein of unknown function, DUF624
FLDIGELM_03826 3e-101 yesJ K Acetyltransferase (GNAT) family
FLDIGELM_03827 5.2e-104 cotJC P Spore Coat
FLDIGELM_03828 1.5e-45 cotJB S CotJB protein
FLDIGELM_03829 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
FLDIGELM_03830 1.3e-151 yesF GM NAD(P)H-binding
FLDIGELM_03831 1.8e-80 yesE S SnoaL-like domain
FLDIGELM_03832 1.2e-103 dhaR3 K Transcriptional regulator
FLDIGELM_03834 2.7e-126 yeeN K transcriptional regulatory protein
FLDIGELM_03836 8.7e-212 S Tetratricopeptide repeat
FLDIGELM_03837 2.3e-50
FLDIGELM_03838 1.4e-53
FLDIGELM_03839 1.2e-121 3.4.24.40 CO amine dehydrogenase activity
FLDIGELM_03841 0.0 L nucleic acid phosphodiester bond hydrolysis
FLDIGELM_03842 5.5e-83 S Protein of unknown function, DUF600
FLDIGELM_03843 6.2e-31 S Colicin immunity protein / pyocin immunity protein
FLDIGELM_03845 1.2e-211 pstS P T5orf172
FLDIGELM_03846 0.0 yeeB L DEAD-like helicases superfamily
FLDIGELM_03847 0.0 yeeA V Type II restriction enzyme, methylase subunits
FLDIGELM_03848 3.2e-53 L Resolvase, N terminal domain
FLDIGELM_03849 3.2e-98 L Recombinase
FLDIGELM_03850 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FLDIGELM_03851 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
FLDIGELM_03852 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FLDIGELM_03853 5.1e-148 yerO K Transcriptional regulator
FLDIGELM_03854 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLDIGELM_03855 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
FLDIGELM_03856 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FLDIGELM_03857 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FLDIGELM_03858 1.6e-123 sapB S MgtC SapB transporter
FLDIGELM_03859 9.2e-197 yerI S homoserine kinase type II (protein kinase fold)
FLDIGELM_03860 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
FLDIGELM_03861 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FLDIGELM_03862 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
FLDIGELM_03863 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
FLDIGELM_03865 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
FLDIGELM_03866 4.8e-51 yerC S protein conserved in bacteria
FLDIGELM_03867 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
FLDIGELM_03868 0.0 yerA 3.5.4.2 F adenine deaminase
FLDIGELM_03869 2.7e-27 S Protein of unknown function (DUF2892)
FLDIGELM_03870 1.9e-231 yjeH E Amino acid permease
FLDIGELM_03871 8.1e-70 K helix_turn_helix ASNC type
FLDIGELM_03872 2.2e-232 purD 6.3.4.13 F Belongs to the GARS family
FLDIGELM_03873 1.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
FLDIGELM_03874 1.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FLDIGELM_03875 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
FLDIGELM_03876 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FLDIGELM_03877 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLDIGELM_03878 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLDIGELM_03879 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FLDIGELM_03880 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
FLDIGELM_03881 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FLDIGELM_03882 1e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FLDIGELM_03883 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FLDIGELM_03884 8e-28 yebG S NETI protein
FLDIGELM_03885 4e-93 yebE S UPF0316 protein
FLDIGELM_03887 6.8e-118 yebC M Membrane
FLDIGELM_03888 7.8e-212 pbuG S permease
FLDIGELM_03889 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
FLDIGELM_03890 0.0 yebA E COG1305 Transglutaminase-like enzymes
FLDIGELM_03891 1.1e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
FLDIGELM_03892 1.7e-176 yeaC S COG0714 MoxR-like ATPases
FLDIGELM_03893 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FLDIGELM_03894 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
FLDIGELM_03895 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
FLDIGELM_03896 3.3e-175 yeaA S Protein of unknown function (DUF4003)
FLDIGELM_03897 7.6e-157 ydjP I Alpha/beta hydrolase family
FLDIGELM_03898 1.4e-34 ydjO S Cold-inducible protein YdjO
FLDIGELM_03900 1.6e-151 ydjN U Involved in the tonB-independent uptake of proteins
FLDIGELM_03901 4.5e-64 ydjM M Lytic transglycolase
FLDIGELM_03902 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
FLDIGELM_03903 2.7e-258 iolT EGP Major facilitator Superfamily
FLDIGELM_03904 8.8e-195 S Ion transport 2 domain protein
FLDIGELM_03905 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
FLDIGELM_03906 1.1e-133 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
FLDIGELM_03907 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FLDIGELM_03908 5.6e-113 pspA KT Phage shock protein A
FLDIGELM_03909 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
FLDIGELM_03910 7.1e-256 gutA G MFS/sugar transport protein
FLDIGELM_03911 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
FLDIGELM_03912 0.0 K NB-ARC domain
FLDIGELM_03913 1.1e-08 ydjC S Abhydrolase domain containing 18
FLDIGELM_03914 4.9e-257 J LlaJI restriction endonuclease
FLDIGELM_03915 1.2e-199 V AAA domain (dynein-related subfamily)
FLDIGELM_03917 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
FLDIGELM_03918 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
FLDIGELM_03919 6.4e-66 KL Phage plasmid primase P4 family
FLDIGELM_03921 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
FLDIGELM_03922 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FLDIGELM_03923 7.9e-129 ydiL S CAAX protease self-immunity
FLDIGELM_03924 2.9e-27 ydiK S Domain of unknown function (DUF4305)
FLDIGELM_03925 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FLDIGELM_03926 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
FLDIGELM_03927 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FLDIGELM_03928 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
FLDIGELM_03929 0.0 ydiF S ABC transporter
FLDIGELM_03930 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FLDIGELM_03931 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
FLDIGELM_03932 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
FLDIGELM_03933 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
FLDIGELM_03934 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FLDIGELM_03936 7.8e-08
FLDIGELM_03937 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
FLDIGELM_03938 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
FLDIGELM_03939 1.2e-84 gerD
FLDIGELM_03940 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
FLDIGELM_03941 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
FLDIGELM_03942 9.7e-66 ybaK S Protein of unknown function (DUF2521)
FLDIGELM_03943 2.4e-144 ybaJ Q Methyltransferase domain
FLDIGELM_03944 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
FLDIGELM_03945 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FLDIGELM_03946 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
FLDIGELM_03947 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLDIGELM_03948 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLDIGELM_03949 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FLDIGELM_03950 3.6e-58 rplQ J Ribosomal protein L17
FLDIGELM_03951 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLDIGELM_03952 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FLDIGELM_03953 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FLDIGELM_03954 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
FLDIGELM_03955 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FLDIGELM_03956 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
FLDIGELM_03957 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
FLDIGELM_03958 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
FLDIGELM_03959 1.8e-72 rplO J binds to the 23S rRNA
FLDIGELM_03960 1.9e-23 rpmD J Ribosomal protein L30
FLDIGELM_03961 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FLDIGELM_03962 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FLDIGELM_03963 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FLDIGELM_03964 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FLDIGELM_03965 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FLDIGELM_03966 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FLDIGELM_03967 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FLDIGELM_03968 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FLDIGELM_03969 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FLDIGELM_03970 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
FLDIGELM_03971 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FLDIGELM_03972 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FLDIGELM_03973 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FLDIGELM_03974 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FLDIGELM_03975 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FLDIGELM_03976 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
FLDIGELM_03977 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
FLDIGELM_03978 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FLDIGELM_03979 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
FLDIGELM_03980 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
FLDIGELM_03981 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FLDIGELM_03982 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FLDIGELM_03983 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
FLDIGELM_03984 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FLDIGELM_03985 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
FLDIGELM_03986 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLDIGELM_03987 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FLDIGELM_03988 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
FLDIGELM_03989 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
FLDIGELM_03990 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FLDIGELM_03991 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
FLDIGELM_03992 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FLDIGELM_03993 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
FLDIGELM_03994 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
FLDIGELM_03995 4.4e-115 sigH K Belongs to the sigma-70 factor family
FLDIGELM_03996 1.2e-88 yacP S RNA-binding protein containing a PIN domain
FLDIGELM_03997 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FLDIGELM_03998 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FLDIGELM_03999 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
FLDIGELM_04000 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
FLDIGELM_04001 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FLDIGELM_04002 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
FLDIGELM_04003 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
FLDIGELM_04004 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
FLDIGELM_04005 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
FLDIGELM_04006 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FLDIGELM_04007 0.0 clpC O Belongs to the ClpA ClpB family
FLDIGELM_04008 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
FLDIGELM_04009 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
FLDIGELM_04010 2.9e-76 ctsR K Belongs to the CtsR family
FLDIGELM_04011 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
FLDIGELM_04012 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FLDIGELM_04013 4.1e-30 yazB K transcriptional
FLDIGELM_04014 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FLDIGELM_04015 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FLDIGELM_04016 3.5e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FLDIGELM_04017 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
FLDIGELM_04018 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
FLDIGELM_04019 6.1e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FLDIGELM_04020 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
FLDIGELM_04021 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
FLDIGELM_04022 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FLDIGELM_04023 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FLDIGELM_04024 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FLDIGELM_04025 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
FLDIGELM_04026 6.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
FLDIGELM_04027 6.1e-180 KLT serine threonine protein kinase
FLDIGELM_04028 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
FLDIGELM_04029 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
FLDIGELM_04032 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
FLDIGELM_04033 1.1e-44 divIC D Septum formation initiator
FLDIGELM_04034 4.3e-107 yabQ S spore cortex biosynthesis protein
FLDIGELM_04035 1.5e-49 yabP S Sporulation protein YabP
FLDIGELM_04036 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
FLDIGELM_04037 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
FLDIGELM_04038 9.3e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
FLDIGELM_04039 1.5e-92 spoVT K stage V sporulation protein
FLDIGELM_04040 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FLDIGELM_04041 2.4e-39 yabK S Peptide ABC transporter permease
FLDIGELM_04042 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
FLDIGELM_04043 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FLDIGELM_04044 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FLDIGELM_04045 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FLDIGELM_04046 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
FLDIGELM_04047 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
FLDIGELM_04048 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
FLDIGELM_04049 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FLDIGELM_04050 8.3e-27 sspF S DNA topological change
FLDIGELM_04051 7.8e-39 veg S protein conserved in bacteria
FLDIGELM_04052 1.6e-136 yabG S peptidase
FLDIGELM_04053 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
FLDIGELM_04054 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FLDIGELM_04055 4.3e-194 rpfB GH23 T protein conserved in bacteria
FLDIGELM_04056 1.8e-144 tatD L hydrolase, TatD
FLDIGELM_04057 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FLDIGELM_04058 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
FLDIGELM_04059 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FLDIGELM_04060 1.5e-49 yazA L endonuclease containing a URI domain
FLDIGELM_04061 5.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
FLDIGELM_04062 4.8e-31 yabA L Involved in initiation control of chromosome replication
FLDIGELM_04063 6.1e-146 yaaT S stage 0 sporulation protein
FLDIGELM_04064 1.1e-181 holB 2.7.7.7 L DNA polymerase III
FLDIGELM_04065 1.5e-71 yaaR S protein conserved in bacteria
FLDIGELM_04066 2.2e-54 yaaQ S protein conserved in bacteria
FLDIGELM_04067 5.3e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FLDIGELM_04068 6.6e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
FLDIGELM_04069 4.5e-203 yaaN P Belongs to the TelA family
FLDIGELM_04070 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
FLDIGELM_04071 3.4e-31 csfB S Inhibitor of sigma-G Gin
FLDIGELM_04072 2.7e-182 yaaC S YaaC-like Protein
FLDIGELM_04073 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
FLDIGELM_04074 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
FLDIGELM_04075 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FLDIGELM_04076 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FLDIGELM_04077 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FLDIGELM_04078 1.3e-09
FLDIGELM_04079 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
FLDIGELM_04080 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
FLDIGELM_04081 5.6e-215 yaaH M Glycoside Hydrolase Family
FLDIGELM_04082 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
FLDIGELM_04083 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
FLDIGELM_04084 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FLDIGELM_04085 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FLDIGELM_04086 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FLDIGELM_04087 7.9e-32 yaaL S Protein of unknown function (DUF2508)
FLDIGELM_04088 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
FLDIGELM_04089 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDIGELM_04090 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FLDIGELM_04091 3.4e-39 S COG NOG14552 non supervised orthologous group
FLDIGELM_04096 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)