ORF_ID e_value Gene_name EC_number CAZy COGs Description
KHHCDELJ_00011 1.2e-263 L COG2963 Transposase and inactivated derivatives
KHHCDELJ_00012 8.5e-77
KHHCDELJ_00013 6e-82 S COG NOG38524 non supervised orthologous group
KHHCDELJ_00017 7.1e-74 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
KHHCDELJ_00018 0.0 L Helicase C-terminal domain protein
KHHCDELJ_00019 1.6e-45 L Helicase C-terminal domain protein
KHHCDELJ_00021 1.2e-188 fhaB M Rib/alpha-like repeat
KHHCDELJ_00022 2.1e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
KHHCDELJ_00023 2.1e-93 F Nucleoside 2-deoxyribosyltransferase
KHHCDELJ_00024 4.5e-160 hipB K Helix-turn-helix
KHHCDELJ_00025 3.2e-152 I alpha/beta hydrolase fold
KHHCDELJ_00026 2.7e-111 yjbF S SNARE associated Golgi protein
KHHCDELJ_00027 1.4e-101 J Acetyltransferase (GNAT) domain
KHHCDELJ_00028 1.8e-253 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHHCDELJ_00029 7.4e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KHHCDELJ_00030 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KHHCDELJ_00031 7.5e-25 secG U Preprotein translocase
KHHCDELJ_00032 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHHCDELJ_00033 4.7e-180 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHHCDELJ_00034 2.9e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
KHHCDELJ_00035 2.3e-223 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
KHHCDELJ_00042 5.8e-138 terC P Integral membrane protein TerC family
KHHCDELJ_00043 6.6e-55 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
KHHCDELJ_00044 2.3e-133 cobB K SIR2 family
KHHCDELJ_00045 1.7e-84
KHHCDELJ_00046 1.2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHHCDELJ_00047 1.9e-180 S Alpha/beta hydrolase of unknown function (DUF915)
KHHCDELJ_00048 3.5e-52 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHHCDELJ_00049 2.5e-71 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHHCDELJ_00050 7.7e-137 ypuA S Protein of unknown function (DUF1002)
KHHCDELJ_00051 7.3e-160 2.4.1.293 GT2 M Glycosyltransferase like family 2
KHHCDELJ_00052 5.6e-126 S Alpha/beta hydrolase family
KHHCDELJ_00053 8.3e-148 K Helix-turn-helix XRE-family like proteins
KHHCDELJ_00054 2.9e-51
KHHCDELJ_00058 6.7e-123 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHHCDELJ_00059 2.2e-37 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHHCDELJ_00060 2.9e-260 qacA EGP Major facilitator Superfamily
KHHCDELJ_00061 1.5e-30 cydA 1.10.3.14 C ubiquinol oxidase
KHHCDELJ_00062 2.3e-116 ndh 1.6.99.3 C NADH dehydrogenase
KHHCDELJ_00063 4.4e-91 ndh 1.6.99.3 C NADH dehydrogenase
KHHCDELJ_00064 3.9e-119 3.6.1.27 I Acid phosphatase homologues
KHHCDELJ_00065 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHHCDELJ_00066 2.2e-296 ytgP S Polysaccharide biosynthesis protein
KHHCDELJ_00067 4.8e-16
KHHCDELJ_00068 5.5e-71 K transcriptional regulator
KHHCDELJ_00069 2.8e-17 K transcriptional regulator
KHHCDELJ_00070 1.2e-188 lacR K Transcriptional regulator
KHHCDELJ_00071 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KHHCDELJ_00072 4.3e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KHHCDELJ_00073 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KHHCDELJ_00074 4.7e-309 2.7.7.7 S Domain of unknown function (DUF5060)
KHHCDELJ_00075 1.3e-216 uhpT EGP Major facilitator Superfamily
KHHCDELJ_00076 2.1e-174 rbsR K helix_turn _helix lactose operon repressor
KHHCDELJ_00077 0.0 3.2.1.40 G Alpha-L-rhamnosidase N-terminal domain
KHHCDELJ_00078 2.4e-30 G polysaccharide catabolic process
KHHCDELJ_00079 7.3e-177 I alpha/beta hydrolase fold
KHHCDELJ_00080 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHHCDELJ_00081 5.7e-155 licT K CAT RNA binding domain
KHHCDELJ_00082 2.4e-258 G Protein of unknown function (DUF4038)
KHHCDELJ_00083 5.7e-175 rbsB G Periplasmic binding protein domain
KHHCDELJ_00084 2e-147 rbsC U Belongs to the binding-protein-dependent transport system permease family
KHHCDELJ_00086 5.8e-258 rbsA 3.6.3.17 G ABC transporter
KHHCDELJ_00087 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KHHCDELJ_00088 1.5e-65 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHHCDELJ_00089 1.7e-42 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHHCDELJ_00090 2.7e-47 G isomerase
KHHCDELJ_00091 9.2e-201 G isomerase
KHHCDELJ_00092 2.2e-97 macB_3 V ABC transporter, ATP-binding protein
KHHCDELJ_00093 1.6e-103 S ECF transporter, substrate-specific component
KHHCDELJ_00094 5.6e-186 tcsA S ABC transporter substrate-binding protein PnrA-like
KHHCDELJ_00095 2e-180 tcsA S ABC transporter substrate-binding protein PnrA-like
KHHCDELJ_00096 1.7e-287 xylG 3.6.3.17 S ABC transporter
KHHCDELJ_00097 3.8e-106 yufP S Belongs to the binding-protein-dependent transport system permease family
KHHCDELJ_00098 1.1e-84 yufP S Belongs to the binding-protein-dependent transport system permease family
KHHCDELJ_00099 2.4e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
KHHCDELJ_00100 1.7e-159 yeaE S Aldo/keto reductase family
KHHCDELJ_00101 2.5e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHHCDELJ_00102 4.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KHHCDELJ_00103 1.4e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KHHCDELJ_00104 5.4e-56 cof S haloacid dehalogenase-like hydrolase
KHHCDELJ_00105 1.5e-77 cof S haloacid dehalogenase-like hydrolase
KHHCDELJ_00106 1.1e-231 pbuG S permease
KHHCDELJ_00107 5.3e-250 purD 6.3.4.13 F Belongs to the GARS family
KHHCDELJ_00108 5e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KHHCDELJ_00109 2.7e-111 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KHHCDELJ_00110 9.6e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KHHCDELJ_00111 1.5e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KHHCDELJ_00112 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHHCDELJ_00113 6.1e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHHCDELJ_00114 7.6e-39 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KHHCDELJ_00115 2.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KHHCDELJ_00116 1.5e-70 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHHCDELJ_00117 8.2e-126 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KHHCDELJ_00118 9.6e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KHHCDELJ_00119 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KHHCDELJ_00120 1.1e-124 darA C Flavodoxin
KHHCDELJ_00121 9.7e-142 qmcA O prohibitin homologues
KHHCDELJ_00122 1.1e-50 L RelB antitoxin
KHHCDELJ_00123 2.4e-194 S Bacteriocin helveticin-J
KHHCDELJ_00124 7.9e-293 M Peptidase family M1 domain
KHHCDELJ_00125 3.2e-178 S SLAP domain
KHHCDELJ_00126 2.2e-51 K LysR substrate binding domain
KHHCDELJ_00127 4.2e-56 1.3.5.4 S FMN_bind
KHHCDELJ_00128 2.6e-230 1.3.5.4 C FAD binding domain
KHHCDELJ_00129 5.6e-115 K Transcriptional regulator, LysR family
KHHCDELJ_00130 1.5e-38 S Cytochrome B5
KHHCDELJ_00131 5e-167 arbZ I Phosphate acyltransferases
KHHCDELJ_00132 8.4e-184 arbY M Glycosyl transferase family 8
KHHCDELJ_00133 2.2e-187 arbY M Glycosyl transferase family 8
KHHCDELJ_00134 1.1e-158 arbx M Glycosyl transferase family 8
KHHCDELJ_00135 1.3e-53 arbV 2.3.1.51 I Acyl-transferase
KHHCDELJ_00136 1.7e-78 arbV 2.3.1.51 I Acyl-transferase
KHHCDELJ_00137 3e-78
KHHCDELJ_00138 2.8e-288 P ABC transporter
KHHCDELJ_00139 1.4e-295 V ABC-type multidrug transport system, ATPase and permease components
KHHCDELJ_00141 9.7e-132 K response regulator
KHHCDELJ_00142 7.1e-288 vicK 2.7.13.3 T Histidine kinase
KHHCDELJ_00143 1e-259 yycH S YycH protein
KHHCDELJ_00144 9.4e-147 yycI S YycH protein
KHHCDELJ_00145 1.1e-149 vicX 3.1.26.11 S domain protein
KHHCDELJ_00146 8.8e-149 htrA 3.4.21.107 O serine protease
KHHCDELJ_00147 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHHCDELJ_00148 2.4e-150 K Helix-turn-helix XRE-family like proteins
KHHCDELJ_00150 2.1e-258 S CAAX protease self-immunity
KHHCDELJ_00151 4.5e-18
KHHCDELJ_00152 1.1e-121
KHHCDELJ_00153 1.3e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
KHHCDELJ_00154 8.9e-92 P Cobalt transport protein
KHHCDELJ_00155 2.3e-251 cbiO1 S ABC transporter, ATP-binding protein
KHHCDELJ_00156 3.9e-173 K helix_turn_helix, arabinose operon control protein
KHHCDELJ_00157 1.6e-163 htpX O Belongs to the peptidase M48B family
KHHCDELJ_00158 1.4e-93 lemA S LemA family
KHHCDELJ_00159 2.9e-171 ybiR P Citrate transporter
KHHCDELJ_00161 2.2e-69 S Iron-sulphur cluster biosynthesis
KHHCDELJ_00162 1.1e-301 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
KHHCDELJ_00163 1.2e-17
KHHCDELJ_00164 4.4e-98
KHHCDELJ_00165 6.8e-37
KHHCDELJ_00167 1.6e-228 ydaM M Glycosyl transferase family group 2
KHHCDELJ_00168 1.5e-211 G Glycosyl hydrolases family 8
KHHCDELJ_00169 3.7e-122 yfbR S HD containing hydrolase-like enzyme
KHHCDELJ_00170 4e-161 L HNH nucleases
KHHCDELJ_00171 1.1e-62 S Protein of unknown function (DUF805)
KHHCDELJ_00172 6.3e-110 S Protein of unknown function (DUF805)
KHHCDELJ_00173 2.1e-137 glnQ E ABC transporter, ATP-binding protein
KHHCDELJ_00174 1e-293 glnP P ABC transporter permease
KHHCDELJ_00175 5.5e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KHHCDELJ_00176 2.5e-64 yeaO S Protein of unknown function, DUF488
KHHCDELJ_00177 5.5e-223 mepA V MATE efflux family protein
KHHCDELJ_00178 6.6e-167 rocF 3.5.3.1, 3.5.3.11 E Arginase family
KHHCDELJ_00179 1.8e-92 S Membrane
KHHCDELJ_00180 3.1e-294 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHHCDELJ_00181 5.5e-295 G phosphotransferase system
KHHCDELJ_00182 1.2e-29 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KHHCDELJ_00183 1.7e-148 ybbH K Helix-turn-helix domain, rpiR family
KHHCDELJ_00184 0.0
KHHCDELJ_00185 4.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KHHCDELJ_00186 7.4e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHHCDELJ_00187 1.1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KHHCDELJ_00188 1.5e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KHHCDELJ_00189 7.4e-201 ecsB U ABC transporter
KHHCDELJ_00190 2e-135 ecsA V ABC transporter, ATP-binding protein
KHHCDELJ_00191 2.8e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
KHHCDELJ_00192 1.4e-56
KHHCDELJ_00193 1.7e-132 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KHHCDELJ_00194 8.4e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
KHHCDELJ_00195 0.0 L AAA domain
KHHCDELJ_00196 2.4e-231 yhaO L Ser Thr phosphatase family protein
KHHCDELJ_00197 6.8e-54 yheA S Belongs to the UPF0342 family
KHHCDELJ_00198 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KHHCDELJ_00199 2.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHHCDELJ_00200 1.6e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KHHCDELJ_00201 6.8e-119
KHHCDELJ_00202 4.1e-192 5.3.3.2 C FMN-dependent dehydrogenase
KHHCDELJ_00203 2.3e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KHHCDELJ_00204 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KHHCDELJ_00205 6.9e-127 M ErfK YbiS YcfS YnhG
KHHCDELJ_00206 1.8e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHHCDELJ_00207 1.7e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KHHCDELJ_00209 6.4e-54 pspC KT PspC domain
KHHCDELJ_00210 1.1e-183 V Beta-lactamase
KHHCDELJ_00211 3e-54 yvlA
KHHCDELJ_00212 7e-258 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
KHHCDELJ_00213 9.1e-40 S Enterocin A Immunity
KHHCDELJ_00214 7.5e-288 S domain, Protein
KHHCDELJ_00215 8.7e-73 S domain, Protein
KHHCDELJ_00216 3.8e-80 yphH S Cupin domain
KHHCDELJ_00217 0.0 sprD D Domain of Unknown Function (DUF1542)
KHHCDELJ_00218 2e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHHCDELJ_00219 3.7e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHHCDELJ_00220 1.1e-34 S Protein of unknown function (DUF2508)
KHHCDELJ_00221 2.3e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHHCDELJ_00222 5.8e-52 yaaQ S Cyclic-di-AMP receptor
KHHCDELJ_00223 2.6e-155 holB 2.7.7.7 L DNA polymerase III
KHHCDELJ_00224 3e-60 yabA L Involved in initiation control of chromosome replication
KHHCDELJ_00225 1.1e-81 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHHCDELJ_00226 5.3e-50 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHHCDELJ_00227 9.6e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
KHHCDELJ_00228 5.2e-87 S ECF transporter, substrate-specific component
KHHCDELJ_00229 1.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KHHCDELJ_00230 3.3e-106 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KHHCDELJ_00231 1.1e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHHCDELJ_00232 1.3e-131 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KHHCDELJ_00233 2.1e-182 S Oxidoreductase family, NAD-binding Rossmann fold
KHHCDELJ_00234 4.9e-128 yegW K UTRA
KHHCDELJ_00235 4.8e-44 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KHHCDELJ_00236 7.1e-142 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KHHCDELJ_00237 1.2e-257 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KHHCDELJ_00238 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KHHCDELJ_00239 0.0 uup S ABC transporter, ATP-binding protein
KHHCDELJ_00240 1.3e-111 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KHHCDELJ_00241 1e-184 scrR K helix_turn _helix lactose operon repressor
KHHCDELJ_00242 5.6e-296 scrB 3.2.1.26 GH32 G invertase
KHHCDELJ_00243 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
KHHCDELJ_00244 5.8e-75
KHHCDELJ_00245 1.1e-77 XK27_02470 K LytTr DNA-binding domain
KHHCDELJ_00246 6.9e-128 liaI S membrane
KHHCDELJ_00247 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHHCDELJ_00248 2.4e-218 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHHCDELJ_00249 3.1e-34 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHHCDELJ_00250 4.5e-39 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHHCDELJ_00251 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHHCDELJ_00252 5.8e-272 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHHCDELJ_00253 2.1e-70 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHHCDELJ_00254 2.7e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KHHCDELJ_00255 4.6e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KHHCDELJ_00256 1.1e-47 yajC U Preprotein translocase
KHHCDELJ_00258 1e-270 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHHCDELJ_00259 2.2e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHHCDELJ_00260 6.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KHHCDELJ_00261 3.3e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KHHCDELJ_00262 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHHCDELJ_00263 2e-42 yrzL S Belongs to the UPF0297 family
KHHCDELJ_00264 2.7e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHHCDELJ_00265 2.8e-51 yrzB S Belongs to the UPF0473 family
KHHCDELJ_00266 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KHHCDELJ_00267 6e-54 trxA O Belongs to the thioredoxin family
KHHCDELJ_00268 5.7e-35 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHHCDELJ_00269 2.3e-69 yslB S Protein of unknown function (DUF2507)
KHHCDELJ_00270 3.8e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KHHCDELJ_00271 1.4e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHHCDELJ_00272 8.2e-130 ykuT M mechanosensitive ion channel
KHHCDELJ_00273 3.6e-09 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHHCDELJ_00274 2.1e-45
KHHCDELJ_00275 7.5e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KHHCDELJ_00276 7.2e-30 ccpA K catabolite control protein A
KHHCDELJ_00277 6e-123 ccpA K catabolite control protein A
KHHCDELJ_00278 2.4e-83 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KHHCDELJ_00279 3.1e-167 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KHHCDELJ_00280 1.9e-55
KHHCDELJ_00281 4.7e-210 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KHHCDELJ_00282 1.1e-46 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KHHCDELJ_00283 1.3e-81 yutD S Protein of unknown function (DUF1027)
KHHCDELJ_00284 7.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KHHCDELJ_00285 1.1e-107 S Protein of unknown function (DUF1461)
KHHCDELJ_00286 2.3e-116 dedA S SNARE-like domain protein
KHHCDELJ_00287 1.1e-150 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KHHCDELJ_00288 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHHCDELJ_00289 7.4e-32 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHHCDELJ_00290 4.8e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KHHCDELJ_00291 6.9e-107 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHHCDELJ_00292 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHHCDELJ_00293 5.1e-251 dnaB L Replication initiation and membrane attachment
KHHCDELJ_00294 6.9e-167 dnaI L Primosomal protein DnaI
KHHCDELJ_00295 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHHCDELJ_00296 5.6e-74 K LytTr DNA-binding domain
KHHCDELJ_00297 5.7e-71 S Protein of unknown function (DUF3021)
KHHCDELJ_00298 3.2e-92
KHHCDELJ_00299 3.7e-73 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHHCDELJ_00300 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KHHCDELJ_00301 1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHHCDELJ_00302 3.5e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KHHCDELJ_00303 1.9e-198 tnpB L Putative transposase DNA-binding domain
KHHCDELJ_00304 1.6e-93 yqeG S HAD phosphatase, family IIIA
KHHCDELJ_00305 1e-212 yqeH S Ribosome biogenesis GTPase YqeH
KHHCDELJ_00306 5.2e-124 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHHCDELJ_00307 1.4e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KHHCDELJ_00308 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KHHCDELJ_00309 2.7e-216 ylbM S Belongs to the UPF0348 family
KHHCDELJ_00310 4.1e-98 yceD S Uncharacterized ACR, COG1399
KHHCDELJ_00311 2.5e-127 K response regulator
KHHCDELJ_00312 1.9e-249 arlS 2.7.13.3 T Histidine kinase
KHHCDELJ_00313 4.3e-159 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHHCDELJ_00314 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KHHCDELJ_00315 1.9e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHHCDELJ_00316 4.7e-63 yodB K Transcriptional regulator, HxlR family
KHHCDELJ_00317 1.2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHHCDELJ_00318 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHHCDELJ_00319 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHHCDELJ_00320 6.7e-170 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
KHHCDELJ_00321 3.6e-254 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KHHCDELJ_00322 1.1e-12 ltrA S Bacterial low temperature requirement A protein (LtrA)
KHHCDELJ_00323 1.7e-35 ltrA S Bacterial low temperature requirement A protein (LtrA)
KHHCDELJ_00324 0.0 O Belongs to the peptidase S8 family
KHHCDELJ_00325 2e-208 O Belongs to the peptidase S8 family
KHHCDELJ_00326 2.3e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
KHHCDELJ_00327 0.0 S membrane
KHHCDELJ_00328 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KHHCDELJ_00329 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KHHCDELJ_00330 1.9e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHHCDELJ_00331 1.2e-118 gluP 3.4.21.105 S Rhomboid family
KHHCDELJ_00332 1.6e-32 yqgQ S Bacterial protein of unknown function (DUF910)
KHHCDELJ_00333 3.3e-65 yqhL P Rhodanese-like protein
KHHCDELJ_00334 2.1e-171 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHHCDELJ_00335 2.3e-237 ynbB 4.4.1.1 P aluminum resistance
KHHCDELJ_00336 8.9e-264 glnA 6.3.1.2 E glutamine synthetase
KHHCDELJ_00337 5.5e-133 ybbM S Uncharacterised protein family (UPF0014)
KHHCDELJ_00338 1.8e-116 ybbL S ABC transporter, ATP-binding protein
KHHCDELJ_00339 4e-167
KHHCDELJ_00340 4.1e-152
KHHCDELJ_00344 6e-44 lmrB EGP Major facilitator Superfamily
KHHCDELJ_00345 4.6e-186 lmrB EGP Major facilitator Superfamily
KHHCDELJ_00346 8.1e-224 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHHCDELJ_00347 3.6e-172 glpK_1 2.7.1.30 G FGGY family of carbohydrate kinases, C-terminal domain
KHHCDELJ_00349 1.3e-176 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
KHHCDELJ_00350 6.9e-80 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
KHHCDELJ_00351 1.9e-65 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
KHHCDELJ_00352 6e-188 purR13 K Bacterial regulatory proteins, lacI family
KHHCDELJ_00353 1.6e-194 S DUF218 domain
KHHCDELJ_00354 2.7e-120 S CAAX protease self-immunity
KHHCDELJ_00355 1.5e-68 K Helix-turn-helix XRE-family like proteins
KHHCDELJ_00356 3.2e-97 M CHAP domain
KHHCDELJ_00357 2.8e-154 mutR K Helix-turn-helix XRE-family like proteins
KHHCDELJ_00358 4.3e-286 V ABC transporter transmembrane region
KHHCDELJ_00359 3.5e-72 S Putative adhesin
KHHCDELJ_00360 5e-194 napA P Sodium/hydrogen exchanger family
KHHCDELJ_00361 0.0 cadA P P-type ATPase
KHHCDELJ_00362 2.1e-82 ykuL S (CBS) domain
KHHCDELJ_00363 9.1e-217 ywhK S Membrane
KHHCDELJ_00364 3.6e-40
KHHCDELJ_00365 7.6e-18 S D-Ala-teichoic acid biosynthesis protein
KHHCDELJ_00366 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHHCDELJ_00367 2.6e-241 dltB M MBOAT, membrane-bound O-acyltransferase family
KHHCDELJ_00368 7.4e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHHCDELJ_00369 3.9e-248 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHHCDELJ_00370 2e-177 pbpX2 V Beta-lactamase
KHHCDELJ_00371 2.7e-61
KHHCDELJ_00372 4.4e-126 S Protein of unknown function (DUF975)
KHHCDELJ_00373 4.3e-167 lysA2 M Glycosyl hydrolases family 25
KHHCDELJ_00374 7.4e-289 ytgP S Polysaccharide biosynthesis protein
KHHCDELJ_00375 9.6e-36
KHHCDELJ_00376 0.0 XK27_06780 V ABC transporter permease
KHHCDELJ_00377 5e-125 XK27_06785 V ABC transporter, ATP-binding protein
KHHCDELJ_00378 1.4e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHHCDELJ_00379 5.1e-170 S Alpha/beta hydrolase of unknown function (DUF915)
KHHCDELJ_00380 0.0 clpE O AAA domain (Cdc48 subfamily)
KHHCDELJ_00381 6.6e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KHHCDELJ_00382 0.0 L Transposase
KHHCDELJ_00383 7.1e-122
KHHCDELJ_00384 3.2e-205 cycA E Amino acid permease
KHHCDELJ_00385 3.6e-220 yifK E Amino acid permease
KHHCDELJ_00386 8e-142 puuD S peptidase C26
KHHCDELJ_00387 1.7e-241 steT_1 E amino acid
KHHCDELJ_00388 1.1e-52 yusE CO Thioredoxin
KHHCDELJ_00390 3.6e-117 M1-798 K Rhodanese Homology Domain
KHHCDELJ_00391 1.3e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHHCDELJ_00392 1.1e-118 frnE Q DSBA-like thioredoxin domain
KHHCDELJ_00393 3e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
KHHCDELJ_00394 1.5e-202 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KHHCDELJ_00397 2e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHHCDELJ_00398 3.2e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHHCDELJ_00399 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHHCDELJ_00400 1.5e-30
KHHCDELJ_00401 3.1e-105
KHHCDELJ_00402 1.6e-163 yicL EG EamA-like transporter family
KHHCDELJ_00403 3.2e-167 EG EamA-like transporter family
KHHCDELJ_00404 1.6e-166 EG EamA-like transporter family
KHHCDELJ_00405 9.5e-83 M NlpC/P60 family
KHHCDELJ_00406 7.6e-134 cobQ S glutamine amidotransferase
KHHCDELJ_00407 2.2e-170 L transposase, IS605 OrfB family
KHHCDELJ_00408 3.3e-57 S Protein conserved in bacteria
KHHCDELJ_00409 2.4e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KHHCDELJ_00410 2.3e-159 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHHCDELJ_00411 6.5e-119 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KHHCDELJ_00412 3.4e-16
KHHCDELJ_00413 5e-75
KHHCDELJ_00414 6.8e-295 V ABC transporter transmembrane region
KHHCDELJ_00415 6.7e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
KHHCDELJ_00416 4.8e-179 yvdE K helix_turn _helix lactose operon repressor
KHHCDELJ_00417 9.4e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHHCDELJ_00418 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
KHHCDELJ_00419 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
KHHCDELJ_00420 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KHHCDELJ_00421 9.6e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KHHCDELJ_00422 7.7e-64 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KHHCDELJ_00423 2.9e-215 pbpX1 V Beta-lactamase
KHHCDELJ_00424 0.0 L Helicase C-terminal domain protein
KHHCDELJ_00425 1e-273 E amino acid
KHHCDELJ_00426 1.2e-103 xth 3.1.11.2 L exodeoxyribonuclease III
KHHCDELJ_00427 2.4e-23 xth 3.1.11.2 L exodeoxyribonuclease III
KHHCDELJ_00428 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHHCDELJ_00429 2.8e-15 S endonuclease exonuclease phosphatase family protein
KHHCDELJ_00430 2.7e-134 S endonuclease exonuclease phosphatase family protein
KHHCDELJ_00431 6.5e-30 S endonuclease exonuclease phosphatase family protein
KHHCDELJ_00432 6.2e-151 3.1.3.102, 3.1.3.104 S hydrolase
KHHCDELJ_00433 0.0 tetP J elongation factor G
KHHCDELJ_00434 4e-138 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KHHCDELJ_00435 1.5e-178 ABC-SBP S ABC transporter
KHHCDELJ_00436 2.6e-126 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KHHCDELJ_00437 2.6e-135 XK27_08845 S ABC transporter, ATP-binding protein
KHHCDELJ_00438 1.7e-52
KHHCDELJ_00439 7.6e-247 G Major Facilitator
KHHCDELJ_00440 5.5e-15
KHHCDELJ_00441 3.6e-105 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
KHHCDELJ_00442 7.1e-176 K AI-2E family transporter
KHHCDELJ_00443 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
KHHCDELJ_00444 5.9e-54 S Domain of unknown function (DUF4430)
KHHCDELJ_00445 4.5e-86 S ECF transporter, substrate-specific component
KHHCDELJ_00446 7.7e-100 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
KHHCDELJ_00447 3.6e-151 S Putative ABC-transporter type IV
KHHCDELJ_00448 7e-37 S LPXTG cell wall anchor motif
KHHCDELJ_00449 1.8e-162 S LPXTG cell wall anchor motif
KHHCDELJ_00450 2.3e-278 pipD E Dipeptidase
KHHCDELJ_00451 3.9e-161 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
KHHCDELJ_00454 5.3e-20 S Protein of unknown function (DUF3923)
KHHCDELJ_00455 6.5e-69 doc S Fic/DOC family
KHHCDELJ_00456 1.3e-31
KHHCDELJ_00457 1.3e-78 L Belongs to the 'phage' integrase family
KHHCDELJ_00458 3.6e-143 L Belongs to the 'phage' integrase family
KHHCDELJ_00459 1.5e-31
KHHCDELJ_00460 4.9e-184 repB EP Plasmid replication protein
KHHCDELJ_00461 8.6e-93
KHHCDELJ_00462 1.1e-206 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KHHCDELJ_00463 4.6e-54
KHHCDELJ_00464 2.1e-114
KHHCDELJ_00465 3e-53
KHHCDELJ_00466 1.6e-58 cadX K helix_turn_helix, Arsenical Resistance Operon Repressor
KHHCDELJ_00467 6.7e-97 cadD P Cadmium resistance transporter
KHHCDELJ_00469 2.6e-238 I Protein of unknown function (DUF2974)
KHHCDELJ_00470 1e-30
KHHCDELJ_00471 1e-16 S CsbD-like
KHHCDELJ_00472 1.6e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KHHCDELJ_00473 8.3e-176 degV S DegV family
KHHCDELJ_00474 1.1e-172 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
KHHCDELJ_00475 5.5e-256 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KHHCDELJ_00476 2.1e-71 rplI J Binds to the 23S rRNA
KHHCDELJ_00477 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KHHCDELJ_00478 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHHCDELJ_00479 2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KHHCDELJ_00480 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
KHHCDELJ_00481 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHHCDELJ_00482 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHHCDELJ_00483 1.3e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHHCDELJ_00484 5.9e-35 yaaA S S4 domain protein YaaA
KHHCDELJ_00485 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KHHCDELJ_00486 3.6e-244 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHHCDELJ_00487 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KHHCDELJ_00488 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KHHCDELJ_00489 5.1e-151 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHHCDELJ_00490 3.9e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHHCDELJ_00491 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KHHCDELJ_00492 6.3e-262 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHHCDELJ_00493 4.6e-85 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KHHCDELJ_00494 5.8e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHHCDELJ_00495 1.1e-281 clcA P chloride
KHHCDELJ_00496 1.2e-213
KHHCDELJ_00497 1.5e-18
KHHCDELJ_00498 5.5e-118 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
KHHCDELJ_00499 2.4e-130 WQ51_05710 S Mitochondrial biogenesis AIM24
KHHCDELJ_00500 2.7e-175 XK27_05540 S DUF218 domain
KHHCDELJ_00501 0.0 copA 3.6.3.54 P P-type ATPase
KHHCDELJ_00502 3.7e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KHHCDELJ_00503 1.8e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KHHCDELJ_00504 3.9e-75 atkY K Penicillinase repressor
KHHCDELJ_00505 3.8e-309 E ABC transporter, substratebinding protein
KHHCDELJ_00506 1.2e-23
KHHCDELJ_00507 3.4e-223 pbuG S permease
KHHCDELJ_00508 3.4e-166 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KHHCDELJ_00509 2e-132 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KHHCDELJ_00510 5.6e-177 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
KHHCDELJ_00511 5e-227 pbuG S permease
KHHCDELJ_00512 6.3e-45 K helix_turn_helix, mercury resistance
KHHCDELJ_00513 3.5e-58 K helix_turn_helix, mercury resistance
KHHCDELJ_00515 0.0 fhaB M Rib/alpha-like repeat
KHHCDELJ_00516 3.3e-290 fhaB M Rib/alpha-like repeat
KHHCDELJ_00517 2.4e-163
KHHCDELJ_00518 0.0 ydgH S MMPL family
KHHCDELJ_00519 2.3e-96 yobS K Bacterial regulatory proteins, tetR family
KHHCDELJ_00520 1.5e-148 3.5.2.6 V Beta-lactamase enzyme family
KHHCDELJ_00521 4e-154 corA P CorA-like Mg2+ transporter protein
KHHCDELJ_00522 1.3e-235 G Bacterial extracellular solute-binding protein
KHHCDELJ_00523 3.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
KHHCDELJ_00524 9.4e-147 gtsC P Binding-protein-dependent transport system inner membrane component
KHHCDELJ_00525 2.2e-154 gtsB P ABC-type sugar transport systems, permease components
KHHCDELJ_00526 7.1e-203 malK P ATPases associated with a variety of cellular activities
KHHCDELJ_00527 2.8e-284 pipD E Dipeptidase
KHHCDELJ_00528 1.6e-157 endA F DNA RNA non-specific endonuclease
KHHCDELJ_00529 1.9e-183 dnaQ 2.7.7.7 L EXOIII
KHHCDELJ_00530 1.4e-155 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHHCDELJ_00531 1.5e-115 yviA S Protein of unknown function (DUF421)
KHHCDELJ_00532 3.4e-74 S Protein of unknown function (DUF3290)
KHHCDELJ_00533 0.0 sdrF M domain protein
KHHCDELJ_00534 4.5e-140 pnuC H nicotinamide mononucleotide transporter
KHHCDELJ_00535 8e-264
KHHCDELJ_00536 3.5e-48
KHHCDELJ_00537 1.5e-143 S PAS domain
KHHCDELJ_00538 5.6e-89 V ABC transporter transmembrane region
KHHCDELJ_00539 3.9e-196 V ABC transporter transmembrane region
KHHCDELJ_00540 1.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KHHCDELJ_00541 1.8e-127 T Transcriptional regulatory protein, C terminal
KHHCDELJ_00542 1.1e-243 T GHKL domain
KHHCDELJ_00543 2.1e-86 S Peptidase propeptide and YPEB domain
KHHCDELJ_00544 2.3e-97 S Peptidase propeptide and YPEB domain
KHHCDELJ_00545 4.1e-76 yybA 2.3.1.57 K Transcriptional regulator
KHHCDELJ_00546 6.8e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
KHHCDELJ_00547 0.0 E ABC transporter, substratebinding protein
KHHCDELJ_00548 1.1e-54 ypaA S Protein of unknown function (DUF1304)
KHHCDELJ_00549 4.6e-100 S Peptidase propeptide and YPEB domain
KHHCDELJ_00550 9.9e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHHCDELJ_00551 3.5e-171 coaA 2.7.1.33 F Pantothenic acid kinase
KHHCDELJ_00552 6.7e-104 E GDSL-like Lipase/Acylhydrolase
KHHCDELJ_00553 9.9e-82 yjcF S Acetyltransferase (GNAT) domain
KHHCDELJ_00554 2.8e-151 aatB ET ABC transporter substrate-binding protein
KHHCDELJ_00555 9e-110 glnQ 3.6.3.21 E ABC transporter
KHHCDELJ_00556 3e-108 glnP P ABC transporter permease
KHHCDELJ_00557 0.0 helD 3.6.4.12 L DNA helicase
KHHCDELJ_00558 9.9e-126 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KHHCDELJ_00559 8.5e-127 pgm3 5.4.2.11 G Phosphoglycerate mutase family
KHHCDELJ_00560 1.1e-248 V FtsX-like permease family
KHHCDELJ_00561 1.6e-62 V FtsX-like permease family
KHHCDELJ_00562 1.7e-134 cysA V ABC transporter, ATP-binding protein
KHHCDELJ_00563 1.6e-241 S response to antibiotic
KHHCDELJ_00564 8.4e-20
KHHCDELJ_00565 1.3e-38
KHHCDELJ_00566 6e-266 3.6.3.8 P P-type ATPase
KHHCDELJ_00567 1.2e-187 3.6.3.8 P P-type ATPase
KHHCDELJ_00568 2.1e-64 2.7.1.191 G PTS system fructose IIA component
KHHCDELJ_00569 2.1e-48
KHHCDELJ_00570 1.9e-15
KHHCDELJ_00571 4.2e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
KHHCDELJ_00572 1.5e-138 glvR K Helix-turn-helix domain, rpiR family
KHHCDELJ_00573 4.1e-269 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
KHHCDELJ_00574 4.3e-155
KHHCDELJ_00575 3.4e-91
KHHCDELJ_00576 4.2e-106 3.2.2.20 K acetyltransferase
KHHCDELJ_00579 4.4e-311 asdA 4.1.1.12 E Aminotransferase
KHHCDELJ_00580 3.2e-303 aspT P Predicted Permease Membrane Region
KHHCDELJ_00581 4.2e-189 S Domain of unknown function (DUF4767)
KHHCDELJ_00582 2.5e-184 S Membrane
KHHCDELJ_00583 6.4e-150 xth 3.1.11.2 L exodeoxyribonuclease III
KHHCDELJ_00584 7.9e-188 K helix_turn_helix, arabinose operon control protein
KHHCDELJ_00585 7.8e-188 K helix_turn_helix, arabinose operon control protein
KHHCDELJ_00586 4.7e-149 K Helix-turn-helix domain, rpiR family
KHHCDELJ_00587 9.6e-106 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KHHCDELJ_00588 5.3e-84 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
KHHCDELJ_00589 3.8e-114 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KHHCDELJ_00590 1.4e-31 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KHHCDELJ_00591 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHHCDELJ_00592 1.6e-298 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHHCDELJ_00593 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHHCDELJ_00594 2.5e-158 K CAT RNA binding domain
KHHCDELJ_00595 1.3e-42 M Leucine-rich repeat (LRR) protein
KHHCDELJ_00596 0.0 M Leucine-rich repeat (LRR) protein
KHHCDELJ_00598 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KHHCDELJ_00599 1.2e-91
KHHCDELJ_00600 1.6e-182
KHHCDELJ_00601 1.1e-119 S Uncharacterised protein conserved in bacteria (DUF2326)
KHHCDELJ_00602 1.4e-142 S Uncharacterised protein conserved in bacteria (DUF2326)
KHHCDELJ_00603 7.6e-10
KHHCDELJ_00610 2.2e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KHHCDELJ_00611 2.5e-49 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KHHCDELJ_00612 2.3e-63 L PFAM Integrase catalytic region
KHHCDELJ_00613 1e-136 L transposase activity
KHHCDELJ_00614 4.8e-80 L COG3547 Transposase and inactivated derivatives
KHHCDELJ_00615 3.3e-115 L COG3547 Transposase and inactivated derivatives
KHHCDELJ_00616 4.6e-266 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
KHHCDELJ_00617 1.2e-200 glf 5.4.99.9 M UDP-galactopyranose mutase
KHHCDELJ_00618 9.6e-125 S Psort location CytoplasmicMembrane, score 9.99
KHHCDELJ_00619 1.2e-188 M Glycosyltransferase like family 2
KHHCDELJ_00620 5.7e-118 M transferase activity, transferring glycosyl groups
KHHCDELJ_00621 2.5e-166 glfT1 1.1.1.133 S Glycosyltransferase like family 2
KHHCDELJ_00622 1.6e-148 cps1D M Domain of unknown function (DUF4422)
KHHCDELJ_00623 1.1e-123 rfbP M Bacterial sugar transferase
KHHCDELJ_00624 1.8e-147 ywqE 3.1.3.48 GM PHP domain protein
KHHCDELJ_00625 9.6e-125 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KHHCDELJ_00626 1.6e-141 epsB M biosynthesis protein
KHHCDELJ_00627 4e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHHCDELJ_00628 4e-205 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHHCDELJ_00629 3.2e-189 S Cysteine-rich secretory protein family
KHHCDELJ_00630 0.0 2.7.13.3 M Mycoplasma protein of unknown function, DUF285
KHHCDELJ_00631 5.9e-43 2.7.13.3 M Mycoplasma protein of unknown function, DUF285
KHHCDELJ_00632 3.7e-128 M NlpC/P60 family
KHHCDELJ_00633 2.3e-126 M NlpC P60 family protein
KHHCDELJ_00634 7.6e-84 M NlpC/P60 family
KHHCDELJ_00635 1.8e-85 gmk2 2.7.4.8 F Guanylate kinase homologues.
KHHCDELJ_00636 5.6e-33
KHHCDELJ_00637 1e-279 S O-antigen ligase like membrane protein
KHHCDELJ_00638 8.1e-111
KHHCDELJ_00639 3.8e-78 nrdI F NrdI Flavodoxin like
KHHCDELJ_00640 1.7e-181 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHHCDELJ_00641 7.8e-78
KHHCDELJ_00642 7.7e-137 yvpB S Peptidase_C39 like family
KHHCDELJ_00643 5.2e-53 yitW S Iron-sulfur cluster assembly protein
KHHCDELJ_00644 8.8e-47 sufB O assembly protein SufB
KHHCDELJ_00645 4.6e-35 sufC O FeS assembly ATPase SufC
KHHCDELJ_00646 7.8e-85 S Threonine/Serine exporter, ThrE
KHHCDELJ_00647 1.7e-137 thrE S Putative threonine/serine exporter
KHHCDELJ_00648 2.1e-293 S ABC transporter
KHHCDELJ_00649 3.6e-61
KHHCDELJ_00650 1.3e-45 rimL J Acetyltransferase (GNAT) domain
KHHCDELJ_00651 1.5e-223 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHHCDELJ_00652 1e-54 pepF E oligoendopeptidase F
KHHCDELJ_00653 1.1e-253 pepF E oligoendopeptidase F
KHHCDELJ_00654 6.7e-44 P transmembrane transport
KHHCDELJ_00655 2.6e-25 lctP C L-lactate permease
KHHCDELJ_00656 3.5e-228 lctP C L-lactate permease
KHHCDELJ_00657 1.4e-62 pdxH S Pyridoxamine 5'-phosphate oxidase
KHHCDELJ_00658 7.9e-135 znuB U ABC 3 transport family
KHHCDELJ_00659 1e-116 fhuC P ABC transporter
KHHCDELJ_00660 6.4e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
KHHCDELJ_00661 2.5e-43 K helix_turn_helix, Arsenical Resistance Operon Repressor
KHHCDELJ_00662 5.1e-75 K LytTr DNA-binding domain
KHHCDELJ_00663 5.5e-47 S Protein of unknown function (DUF3021)
KHHCDELJ_00664 2.4e-259 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
KHHCDELJ_00665 7.5e-93 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
KHHCDELJ_00666 3.3e-169 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KHHCDELJ_00667 5.2e-136 fruR K DeoR C terminal sensor domain
KHHCDELJ_00668 6.3e-196 fic S Fic/DOC family
KHHCDELJ_00669 1.9e-217 natB CP ABC-2 family transporter protein
KHHCDELJ_00670 2.6e-166 natA S ABC transporter, ATP-binding protein
KHHCDELJ_00671 6.2e-08
KHHCDELJ_00672 4e-69
KHHCDELJ_00673 2.1e-25
KHHCDELJ_00674 8.2e-31 yozG K Transcriptional regulator
KHHCDELJ_00675 9e-90
KHHCDELJ_00676 8.8e-21
KHHCDELJ_00681 8.1e-209 blpT
KHHCDELJ_00682 3.4e-106 M Transport protein ComB
KHHCDELJ_00683 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KHHCDELJ_00684 4.2e-07
KHHCDELJ_00686 1.2e-146 K LytTr DNA-binding domain
KHHCDELJ_00687 2.3e-232 2.7.13.3 T GHKL domain
KHHCDELJ_00691 7e-110
KHHCDELJ_00693 5.1e-109 S CAAX protease self-immunity
KHHCDELJ_00694 1.2e-216 S CAAX protease self-immunity
KHHCDELJ_00695 1.4e-37 S Enterocin A Immunity
KHHCDELJ_00696 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KHHCDELJ_00697 1.1e-26
KHHCDELJ_00698 1.8e-32
KHHCDELJ_00699 4e-53 S Enterocin A Immunity
KHHCDELJ_00700 9.4e-49 S Enterocin A Immunity
KHHCDELJ_00701 7.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KHHCDELJ_00702 2.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHHCDELJ_00703 5.8e-195 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
KHHCDELJ_00704 2.5e-121 K response regulator
KHHCDELJ_00705 0.0 V ABC transporter
KHHCDELJ_00706 1.3e-304 V ABC transporter, ATP-binding protein
KHHCDELJ_00707 2e-138 XK27_01040 S Protein of unknown function (DUF1129)
KHHCDELJ_00708 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KHHCDELJ_00709 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
KHHCDELJ_00710 3.4e-155 spo0J K Belongs to the ParB family
KHHCDELJ_00711 1.3e-137 soj D Sporulation initiation inhibitor
KHHCDELJ_00712 7.2e-147 noc K Belongs to the ParB family
KHHCDELJ_00713 3.8e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KHHCDELJ_00714 7.9e-54 cvpA S Colicin V production protein
KHHCDELJ_00715 3.5e-182 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHHCDELJ_00716 2.5e-149 3.1.3.48 T Tyrosine phosphatase family
KHHCDELJ_00717 3.1e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
KHHCDELJ_00718 7.6e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
KHHCDELJ_00719 1.3e-111 K WHG domain
KHHCDELJ_00720 1.5e-36
KHHCDELJ_00721 1.1e-277 pipD E Dipeptidase
KHHCDELJ_00722 9.8e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KHHCDELJ_00723 1.3e-180 hrtB V ABC transporter permease
KHHCDELJ_00724 4.8e-96 ygfC K Bacterial regulatory proteins, tetR family
KHHCDELJ_00725 2.4e-112 3.1.3.73 G phosphoglycerate mutase
KHHCDELJ_00726 2e-140 aroD S Alpha/beta hydrolase family
KHHCDELJ_00727 2e-143 S Belongs to the UPF0246 family
KHHCDELJ_00728 3.8e-119
KHHCDELJ_00729 5.9e-129 2.7.7.12 C Domain of unknown function (DUF4931)
KHHCDELJ_00730 9.3e-220 S Putative peptidoglycan binding domain
KHHCDELJ_00731 2.6e-26
KHHCDELJ_00732 1.3e-252 dtpT U amino acid peptide transporter
KHHCDELJ_00733 0.0 pepN 3.4.11.2 E aminopeptidase
KHHCDELJ_00734 2.9e-39 pepN 3.4.11.2 E aminopeptidase
KHHCDELJ_00735 4.5e-61 lysM M LysM domain
KHHCDELJ_00736 1.4e-104
KHHCDELJ_00737 5.4e-54
KHHCDELJ_00738 2.8e-102 mdtG EGP Major Facilitator Superfamily
KHHCDELJ_00739 2.9e-114 mdtG EGP Major facilitator Superfamily
KHHCDELJ_00741 6e-213 I transferase activity, transferring acyl groups other than amino-acyl groups
KHHCDELJ_00742 1.2e-91 ymdB S Macro domain protein
KHHCDELJ_00743 0.0 nisT V ABC transporter
KHHCDELJ_00744 3.7e-07
KHHCDELJ_00746 1.6e-146 K Helix-turn-helix XRE-family like proteins
KHHCDELJ_00747 6.7e-84
KHHCDELJ_00748 1.4e-148 malG P ABC transporter permease
KHHCDELJ_00749 1.9e-124 malF P Binding-protein-dependent transport system inner membrane component
KHHCDELJ_00750 2e-115 malF P Binding-protein-dependent transport system inner membrane component
KHHCDELJ_00751 5.9e-214 malE G Bacterial extracellular solute-binding protein
KHHCDELJ_00752 1.6e-210 msmX P Belongs to the ABC transporter superfamily
KHHCDELJ_00753 4.2e-189 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
KHHCDELJ_00754 2.5e-136 manY G PTS system
KHHCDELJ_00755 5.7e-135 manN G system, mannose fructose sorbose family IID component
KHHCDELJ_00756 9.5e-29 manN G system, mannose fructose sorbose family IID component
KHHCDELJ_00757 4e-65 manO S Domain of unknown function (DUF956)
KHHCDELJ_00758 3.7e-160 K Transcriptional regulator
KHHCDELJ_00759 3.9e-69 S transferase hexapeptide repeat
KHHCDELJ_00760 9.2e-248 cycA E Amino acid permease
KHHCDELJ_00761 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KHHCDELJ_00762 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHHCDELJ_00763 7.3e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHHCDELJ_00764 1.3e-136 4.1.1.44 S Carboxymuconolactone decarboxylase family
KHHCDELJ_00765 9.1e-27 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KHHCDELJ_00766 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
KHHCDELJ_00767 0.0 S TerB-C domain
KHHCDELJ_00768 1.4e-253 P P-loop Domain of unknown function (DUF2791)
KHHCDELJ_00769 0.0 lhr L DEAD DEAH box helicase
KHHCDELJ_00770 4.3e-62
KHHCDELJ_00771 7.1e-231 amtB P ammonium transporter
KHHCDELJ_00772 6.8e-144 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KHHCDELJ_00774 0.0 L Type III restriction enzyme, res subunit
KHHCDELJ_00775 2.5e-267 S AAA ATPase domain
KHHCDELJ_00776 2.8e-48 S AAA ATPase domain
KHHCDELJ_00777 2.9e-106 dam2 2.1.1.72 L DNA methyltransferase
KHHCDELJ_00778 1.7e-26 dam2 2.1.1.72 L DNA methyltransferase
KHHCDELJ_00779 7.1e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KHHCDELJ_00781 1.1e-47
KHHCDELJ_00782 1.9e-211 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KHHCDELJ_00784 7.7e-186 repB EP Plasmid replication protein
KHHCDELJ_00785 2.8e-12
KHHCDELJ_00786 4.9e-229 L Belongs to the 'phage' integrase family
KHHCDELJ_00787 1.3e-69 S Iron-sulphur cluster biosynthesis
KHHCDELJ_00788 5.1e-33
KHHCDELJ_00789 5.9e-67
KHHCDELJ_00790 3.1e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
KHHCDELJ_00791 5.6e-13
KHHCDELJ_00792 2.1e-252 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHHCDELJ_00793 2.5e-161 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHHCDELJ_00794 7.8e-70 M LysM domain protein
KHHCDELJ_00795 4.1e-195 D nuclear chromosome segregation
KHHCDELJ_00796 4.9e-110 5.4.2.11 G Phosphoglycerate mutase family
KHHCDELJ_00797 6.6e-107 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
KHHCDELJ_00798 1e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
KHHCDELJ_00799 5.4e-52 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KHHCDELJ_00800 1.2e-29 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KHHCDELJ_00801 3.9e-184 msmR K helix_turn _helix lactose operon repressor
KHHCDELJ_00802 5.9e-157 G Bacterial extracellular solute-binding protein
KHHCDELJ_00803 1.2e-82 G Bacterial extracellular solute-binding protein
KHHCDELJ_00804 4.5e-163 msmF P ABC-type sugar transport systems, permease components
KHHCDELJ_00805 3.3e-155 msmG G Binding-protein-dependent transport system inner membrane component
KHHCDELJ_00806 7.3e-230 sacA 3.2.1.26 GH32 G Glycosyl hydrolases family 32
KHHCDELJ_00807 6.5e-212 msmX P Belongs to the ABC transporter superfamily
KHHCDELJ_00808 2.6e-285 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
KHHCDELJ_00809 6.1e-70 EGP Major facilitator Superfamily
KHHCDELJ_00811 4.9e-177 pfoS S Phosphotransferase system, EIIC
KHHCDELJ_00812 3.9e-276 slpX S SLAP domain
KHHCDELJ_00815 1.1e-89
KHHCDELJ_00816 3.2e-110
KHHCDELJ_00817 7.3e-124 gntR1 K UTRA
KHHCDELJ_00818 1.5e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
KHHCDELJ_00819 8e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KHHCDELJ_00820 1.1e-206 csaB M Glycosyl transferases group 1
KHHCDELJ_00821 1.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHHCDELJ_00822 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KHHCDELJ_00823 0.0 pacL 3.6.3.8 P P-type ATPase
KHHCDELJ_00824 1.6e-45 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHHCDELJ_00825 1.4e-155 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHHCDELJ_00826 1.1e-256 epsU S Polysaccharide biosynthesis protein
KHHCDELJ_00827 9.7e-137 M Glycosyltransferase sugar-binding region containing DXD motif
KHHCDELJ_00828 4.3e-64 ydcK S Belongs to the SprT family
KHHCDELJ_00830 2.8e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
KHHCDELJ_00831 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KHHCDELJ_00832 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHHCDELJ_00833 1.1e-201 camS S sex pheromone
KHHCDELJ_00834 2.6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHHCDELJ_00835 5.8e-261 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KHHCDELJ_00836 1.9e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHHCDELJ_00837 4.2e-172 yegS 2.7.1.107 G Lipid kinase
KHHCDELJ_00838 6.7e-67 ybhL S Belongs to the BI1 family
KHHCDELJ_00839 4.5e-37 ybhL S Belongs to the BI1 family
KHHCDELJ_00840 4.1e-56
KHHCDELJ_00841 1.5e-245 nhaC C Na H antiporter NhaC
KHHCDELJ_00842 5.7e-96 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHHCDELJ_00843 3.9e-136 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHHCDELJ_00844 1.6e-22
KHHCDELJ_00845 1.1e-62
KHHCDELJ_00846 5.7e-136 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KHHCDELJ_00847 8.9e-176 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KHHCDELJ_00848 3.9e-34 copZ C Heavy-metal-associated domain
KHHCDELJ_00849 5e-96 dps P Belongs to the Dps family
KHHCDELJ_00850 7.6e-74 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KHHCDELJ_00851 1.4e-30 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KHHCDELJ_00852 2.8e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
KHHCDELJ_00853 1.2e-48 5.1.1.13 M Asp/Glu/Hydantoin racemase
KHHCDELJ_00854 6.5e-57 5.1.1.13 M Asp/Glu/Hydantoin racemase
KHHCDELJ_00855 9e-192 L Recombinase
KHHCDELJ_00856 7.8e-94 L Resolvase, N terminal domain
KHHCDELJ_00857 6.7e-150 L Recombinase zinc beta ribbon domain
KHHCDELJ_00858 6.6e-95 MA20_25245 K Acetyltransferase (GNAT) domain
KHHCDELJ_00863 6.9e-135 emrY EGP Major facilitator Superfamily
KHHCDELJ_00864 2.4e-93 emrY EGP Major facilitator Superfamily
KHHCDELJ_00865 6.8e-136 S CAAX protease self-immunity
KHHCDELJ_00866 5e-90 yxdD K Bacterial regulatory proteins, tetR family
KHHCDELJ_00867 0.0 4.2.1.53 S Myosin-crossreactive antigen
KHHCDELJ_00868 8.4e-78 2.3.1.128 K acetyltransferase
KHHCDELJ_00869 1.8e-161 S reductase
KHHCDELJ_00870 3.6e-109 V ABC-type multidrug transport system, ATPase and permease components
KHHCDELJ_00871 5.1e-128 cydD V cysteine transport
KHHCDELJ_00872 2.1e-241 pyrP F Permease
KHHCDELJ_00873 3.3e-83 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHHCDELJ_00874 1.5e-86 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KHHCDELJ_00875 2.4e-50 3.1.3.102, 3.1.3.104 Q phosphatase activity
KHHCDELJ_00876 1.6e-253 emrY EGP Major facilitator Superfamily
KHHCDELJ_00877 4e-215 mdtG EGP Major facilitator Superfamily
KHHCDELJ_00878 1.8e-165 mleP3 S Membrane transport protein
KHHCDELJ_00879 2.1e-210 pepA E M42 glutamyl aminopeptidase
KHHCDELJ_00880 0.0 ybiT S ABC transporter, ATP-binding protein
KHHCDELJ_00881 9.8e-146
KHHCDELJ_00882 9e-150 glnH ET ABC transporter
KHHCDELJ_00883 2.3e-78 K Transcriptional regulator, MarR family
KHHCDELJ_00884 1.1e-306 XK27_09600 V ABC transporter, ATP-binding protein
KHHCDELJ_00885 0.0 V ABC transporter transmembrane region
KHHCDELJ_00886 2.9e-102 S ABC-type cobalt transport system, permease component
KHHCDELJ_00887 7.2e-115 udk 2.7.1.48 F Zeta toxin
KHHCDELJ_00888 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHHCDELJ_00889 3.1e-64 glnH ET ABC transporter substrate-binding protein
KHHCDELJ_00890 1.7e-72 glnH ET ABC transporter substrate-binding protein
KHHCDELJ_00891 6.1e-93 gluC P ABC transporter permease
KHHCDELJ_00892 1.9e-110 glnP P ABC transporter permease
KHHCDELJ_00893 5.5e-95 S Protein of unknown function (DUF2974)
KHHCDELJ_00894 1e-69 S Protein of unknown function (DUF2974)
KHHCDELJ_00895 1.2e-63
KHHCDELJ_00896 4.8e-238 G Bacterial extracellular solute-binding protein
KHHCDELJ_00897 4.1e-163 2.7.7.12 C Domain of unknown function (DUF4931)
KHHCDELJ_00898 5.9e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHHCDELJ_00899 5.9e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHHCDELJ_00900 0.0 kup P Transport of potassium into the cell
KHHCDELJ_00901 6.3e-176 rihB 3.2.2.1 F Nucleoside
KHHCDELJ_00902 3.3e-135 gntR K UbiC transcription regulator-associated domain protein
KHHCDELJ_00903 2.6e-22
KHHCDELJ_00904 1.2e-112
KHHCDELJ_00905 2.9e-285 V ABC transporter transmembrane region
KHHCDELJ_00906 1.8e-153 S hydrolase
KHHCDELJ_00907 5.3e-72 K helix_turn_helix multiple antibiotic resistance protein
KHHCDELJ_00908 2.7e-115 lmrA 3.6.3.44 V ABC transporter
KHHCDELJ_00909 7.9e-177 lmrA 3.6.3.44 V ABC transporter
KHHCDELJ_00910 1.9e-59 S Enterocin A Immunity
KHHCDELJ_00911 1.3e-137 glcR K DeoR C terminal sensor domain
KHHCDELJ_00912 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KHHCDELJ_00913 5.3e-161 rssA S Phospholipase, patatin family
KHHCDELJ_00914 3.8e-224 2.7.13.3 T GHKL domain
KHHCDELJ_00915 5e-145 K LytTr DNA-binding domain
KHHCDELJ_00916 3.4e-222 S CAAX protease self-immunity
KHHCDELJ_00917 2.3e-153 S hydrolase
KHHCDELJ_00918 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
KHHCDELJ_00919 1.9e-147 glvR K Helix-turn-helix domain, rpiR family
KHHCDELJ_00920 2.9e-82
KHHCDELJ_00921 1.1e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHHCDELJ_00922 1.9e-40
KHHCDELJ_00923 1.7e-119 C nitroreductase
KHHCDELJ_00924 1.1e-248 yhdP S Transporter associated domain
KHHCDELJ_00925 3e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KHHCDELJ_00926 1.5e-228 potE E amino acid
KHHCDELJ_00927 1.1e-130 M Glycosyl hydrolases family 25
KHHCDELJ_00928 2.6e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
KHHCDELJ_00929 5.9e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHHCDELJ_00932 0.0 oppA E ABC transporter substrate-binding protein
KHHCDELJ_00933 9.3e-109 oppA E ABC transporter substrate-binding protein
KHHCDELJ_00934 1.7e-221 oppA E ABC transporter substrate-binding protein
KHHCDELJ_00935 2.9e-144 oppC P Binding-protein-dependent transport system inner membrane component
KHHCDELJ_00936 2.5e-175 oppB P ABC transporter permease
KHHCDELJ_00937 6.1e-177 oppF P Belongs to the ABC transporter superfamily
KHHCDELJ_00938 2.5e-197 oppD P Belongs to the ABC transporter superfamily
KHHCDELJ_00939 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHHCDELJ_00940 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KHHCDELJ_00941 6e-140 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHHCDELJ_00942 9.5e-231 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHHCDELJ_00943 2.4e-306 yloV S DAK2 domain fusion protein YloV
KHHCDELJ_00944 6.8e-57 asp S Asp23 family, cell envelope-related function
KHHCDELJ_00945 3.7e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KHHCDELJ_00946 4.2e-52
KHHCDELJ_00947 6.9e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
KHHCDELJ_00948 4.5e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KHHCDELJ_00949 8e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KHHCDELJ_00950 3.3e-188 KLT serine threonine protein kinase
KHHCDELJ_00951 7.9e-143 KLT serine threonine protein kinase
KHHCDELJ_00952 2.3e-139 stp 3.1.3.16 T phosphatase
KHHCDELJ_00953 1.8e-223 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHHCDELJ_00954 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHHCDELJ_00955 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHHCDELJ_00956 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KHHCDELJ_00957 1.5e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KHHCDELJ_00958 1.8e-80 6.3.3.2 S ASCH
KHHCDELJ_00959 4.7e-310 recN L May be involved in recombinational repair of damaged DNA
KHHCDELJ_00960 3.5e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KHHCDELJ_00961 6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KHHCDELJ_00962 3.4e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHHCDELJ_00963 7.3e-213 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHHCDELJ_00964 1.9e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHHCDELJ_00965 3.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHHCDELJ_00966 6.8e-72 yqhY S Asp23 family, cell envelope-related function
KHHCDELJ_00967 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHHCDELJ_00968 3.2e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KHHCDELJ_00969 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KHHCDELJ_00970 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KHHCDELJ_00971 2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHHCDELJ_00972 6.8e-259 S Uncharacterized protein conserved in bacteria (DUF2325)
KHHCDELJ_00973 1.8e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KHHCDELJ_00974 3.7e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KHHCDELJ_00975 1.3e-105 Q Imidazolonepropionase and related amidohydrolases
KHHCDELJ_00976 3.2e-109 Q Imidazolonepropionase and related amidohydrolases
KHHCDELJ_00978 6.7e-60 oppA E ABC transporter
KHHCDELJ_00979 9.2e-98 E ABC transporter
KHHCDELJ_00980 3.7e-153 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
KHHCDELJ_00981 5e-311 S Predicted membrane protein (DUF2207)
KHHCDELJ_00982 3.6e-154 cinI S Serine hydrolase (FSH1)
KHHCDELJ_00983 2e-185 M Glycosyl hydrolases family 25
KHHCDELJ_00985 1.7e-165 S Membrane
KHHCDELJ_00986 6.5e-178 I Carboxylesterase family
KHHCDELJ_00987 1e-65 arsC 1.20.4.1 P Belongs to the ArsC family
KHHCDELJ_00988 5.2e-295 V ABC-type multidrug transport system, ATPase and permease components
KHHCDELJ_00989 3.2e-270 V ABC-type multidrug transport system, ATPase and permease components
KHHCDELJ_00990 1.5e-152 S haloacid dehalogenase-like hydrolase
KHHCDELJ_00991 8.1e-253
KHHCDELJ_00992 0.0 lacA 3.2.1.23 G -beta-galactosidase
KHHCDELJ_00993 0.0 yic1 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
KHHCDELJ_00994 7.7e-309 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHHCDELJ_00995 1.1e-166 bglK 2.7.1.2, 2.7.1.85 GK ROK family
KHHCDELJ_00996 7.3e-206 xylR GK ROK family
KHHCDELJ_00997 1.1e-236 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHHCDELJ_00998 6.4e-100 S Bacterial PH domain
KHHCDELJ_00999 3.4e-16
KHHCDELJ_01000 4.2e-65 ps301 K sequence-specific DNA binding
KHHCDELJ_01001 2.3e-47 S Motility quorum-sensing regulator, toxin of MqsA
KHHCDELJ_01002 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KHHCDELJ_01003 8.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KHHCDELJ_01004 4.9e-47
KHHCDELJ_01005 6.6e-151 glcU U sugar transport
KHHCDELJ_01006 0.0
KHHCDELJ_01008 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KHHCDELJ_01009 7.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KHHCDELJ_01010 1e-150 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHHCDELJ_01011 5.5e-55 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHHCDELJ_01012 8.5e-184 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KHHCDELJ_01013 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHHCDELJ_01014 3.3e-26 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHHCDELJ_01015 3.6e-129 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHHCDELJ_01016 1.5e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KHHCDELJ_01017 9.2e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHHCDELJ_01018 1.2e-117 GM NmrA-like family
KHHCDELJ_01019 0.0 3.6.3.8 P P-type ATPase
KHHCDELJ_01020 3.9e-221 clcA P chloride
KHHCDELJ_01021 0.0 UW LPXTG-motif cell wall anchor domain protein
KHHCDELJ_01022 8.8e-95 wecD K acetyltransferase
KHHCDELJ_01023 1e-50
KHHCDELJ_01024 1.5e-147 metQ2 P Belongs to the nlpA lipoprotein family
KHHCDELJ_01025 8.8e-47
KHHCDELJ_01026 8.1e-125 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KHHCDELJ_01027 6.5e-152 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KHHCDELJ_01028 5.7e-52 S Iron-sulfur cluster assembly protein
KHHCDELJ_01029 5.7e-17 oppA E ABC transporter substrate-binding protein
KHHCDELJ_01030 2.4e-153 oppA E ABC transporter substrate-binding protein
KHHCDELJ_01031 3.7e-126 oppA E ABC transporter substrate-binding protein
KHHCDELJ_01033 9.1e-264 npr 1.11.1.1 C NADH oxidase
KHHCDELJ_01034 3.9e-62 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
KHHCDELJ_01035 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
KHHCDELJ_01036 1.8e-26 ylbE GM NAD(P)H-binding
KHHCDELJ_01037 1.1e-59 ylbE GM NAD(P)H-binding
KHHCDELJ_01038 1.7e-57 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KHHCDELJ_01039 2.6e-64 S ASCH domain
KHHCDELJ_01040 1.1e-118 S GyrI-like small molecule binding domain
KHHCDELJ_01042 7.7e-160 K Bacterial regulatory helix-turn-helix protein, lysR family
KHHCDELJ_01043 3.2e-153 1.3.5.4 C FMN_bind
KHHCDELJ_01044 1.1e-244 1.3.5.4 C FMN_bind
KHHCDELJ_01047 2e-208 2.7.7.65 T GGDEF domain
KHHCDELJ_01048 1e-130 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
KHHCDELJ_01049 3.6e-143 T EAL domain
KHHCDELJ_01050 1.5e-46 pgaC GT2 M Glycosyl transferase
KHHCDELJ_01051 3.3e-183 pgaC GT2 M Glycosyl transferase
KHHCDELJ_01052 1e-90
KHHCDELJ_01053 5.7e-177 C Oxidoreductase
KHHCDELJ_01054 8.1e-09 L Probable transposase
KHHCDELJ_01055 9.3e-214 L TIGRFAM transposase, IS605 OrfB family
KHHCDELJ_01056 6e-27 C pentaerythritol trinitrate reductase activity
KHHCDELJ_01057 4e-109 pncA Q Isochorismatase family
KHHCDELJ_01058 2.9e-13
KHHCDELJ_01059 1.1e-278 yjeM E Amino Acid
KHHCDELJ_01060 2.4e-127 S Alpha beta hydrolase
KHHCDELJ_01062 2.4e-128
KHHCDELJ_01063 9e-127 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
KHHCDELJ_01064 9.2e-71 O OsmC-like protein
KHHCDELJ_01065 1.8e-212 EGP Major facilitator Superfamily
KHHCDELJ_01066 3.5e-233 sptS 2.7.13.3 T Histidine kinase
KHHCDELJ_01067 4.6e-88 K response regulator
KHHCDELJ_01068 6.3e-11 K response regulator
KHHCDELJ_01069 1.7e-113 2.7.6.5 T Region found in RelA / SpoT proteins
KHHCDELJ_01070 1.3e-145 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
KHHCDELJ_01071 1.2e-103 dhaL 2.7.1.121 S Dak2
KHHCDELJ_01072 2.1e-61 dhaM 2.7.1.121 S PTS system fructose IIA component
KHHCDELJ_01073 5.6e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KHHCDELJ_01074 1.6e-282 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
KHHCDELJ_01075 0.0 rafA 3.2.1.22 G alpha-galactosidase
KHHCDELJ_01076 2.3e-209 msmX P Belongs to the ABC transporter superfamily
KHHCDELJ_01077 5.7e-152 msmG P Binding-protein-dependent transport system inner membrane component
KHHCDELJ_01078 1.8e-156 msmF P Binding-protein-dependent transport system inner membrane component
KHHCDELJ_01079 4e-242 msmE G Bacterial extracellular solute-binding protein
KHHCDELJ_01080 2.4e-158 msmR K helix_turn_helix, arabinose operon control protein
KHHCDELJ_01081 1.4e-69 merR K MerR HTH family regulatory protein
KHHCDELJ_01082 6.3e-171 lmrB EGP Major facilitator Superfamily
KHHCDELJ_01083 1e-85 lmrB EGP Major facilitator Superfamily
KHHCDELJ_01084 8.2e-85 S Domain of unknown function (DUF4811)
KHHCDELJ_01085 5.3e-52 S Domain of unknown function (DUF4160)
KHHCDELJ_01086 1.2e-45
KHHCDELJ_01088 1.1e-39 C FMN binding
KHHCDELJ_01089 1.8e-167 S SLAP domain
KHHCDELJ_01090 1.2e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KHHCDELJ_01091 4.3e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KHHCDELJ_01092 1.3e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KHHCDELJ_01093 2.3e-187 M domain protein
KHHCDELJ_01094 8.8e-113
KHHCDELJ_01095 0.0 lacZ 3.2.1.23 G -beta-galactosidase
KHHCDELJ_01096 0.0 lacS G Transporter
KHHCDELJ_01097 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHHCDELJ_01098 1.2e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KHHCDELJ_01099 1.4e-23
KHHCDELJ_01100 6.4e-116 rsmC 2.1.1.172 J Methyltransferase
KHHCDELJ_01101 1.5e-123 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
KHHCDELJ_01102 2.2e-47 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KHHCDELJ_01103 1.6e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHHCDELJ_01104 2.2e-10
KHHCDELJ_01105 2.2e-210 yfdV S Membrane transport protein
KHHCDELJ_01106 2e-118 phoU P Plays a role in the regulation of phosphate uptake
KHHCDELJ_01107 7e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHHCDELJ_01108 4.2e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHHCDELJ_01109 2.6e-155 pstA P Phosphate transport system permease protein PstA
KHHCDELJ_01110 5.2e-176 pstC P probably responsible for the translocation of the substrate across the membrane
KHHCDELJ_01111 1.5e-158 pstS P Phosphate
KHHCDELJ_01112 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KHHCDELJ_01113 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHHCDELJ_01114 6.2e-102 nusG K Participates in transcription elongation, termination and antitermination
KHHCDELJ_01115 7.8e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KHHCDELJ_01116 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHHCDELJ_01117 8.1e-173 K helix_turn_helix, arabinose operon control protein
KHHCDELJ_01118 3.5e-213 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KHHCDELJ_01119 4.8e-47 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KHHCDELJ_01120 3.5e-114
KHHCDELJ_01121 2.2e-34
KHHCDELJ_01122 3.5e-94 sigH K Belongs to the sigma-70 factor family
KHHCDELJ_01123 2e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHHCDELJ_01124 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHHCDELJ_01125 6.8e-278 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHHCDELJ_01126 2.2e-190 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHHCDELJ_01127 3.5e-82 gltX 6.1.1.17, 6.1.1.24 J tRNA synthetases class I (E and Q), catalytic domain
KHHCDELJ_01128 9.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHHCDELJ_01129 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KHHCDELJ_01130 7e-52
KHHCDELJ_01131 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
KHHCDELJ_01132 6.4e-184 S AAA domain
KHHCDELJ_01133 2.4e-80 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHHCDELJ_01134 2.2e-19
KHHCDELJ_01135 2.1e-163 czcD P cation diffusion facilitator family transporter
KHHCDELJ_01136 4.7e-128 pgm3 5.4.2.11 G Belongs to the phosphoglycerate mutase family
KHHCDELJ_01137 5.8e-111 S membrane transporter protein
KHHCDELJ_01138 2.5e-118 3.1.3.102, 3.1.3.104, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KHHCDELJ_01139 2.5e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KHHCDELJ_01140 1.4e-20
KHHCDELJ_01141 2.8e-11
KHHCDELJ_01142 3.5e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
KHHCDELJ_01143 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHHCDELJ_01144 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KHHCDELJ_01145 9.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHHCDELJ_01146 2.4e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHHCDELJ_01147 2.8e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHHCDELJ_01148 8.2e-61 rplQ J Ribosomal protein L17
KHHCDELJ_01149 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHHCDELJ_01150 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHHCDELJ_01151 2.1e-53 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHHCDELJ_01152 2.7e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KHHCDELJ_01153 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHHCDELJ_01154 2e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KHHCDELJ_01155 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KHHCDELJ_01156 2e-71 rplO J Binds to the 23S rRNA
KHHCDELJ_01157 2.3e-24 rpmD J Ribosomal protein L30
KHHCDELJ_01158 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHHCDELJ_01159 2.1e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHHCDELJ_01160 2.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHHCDELJ_01161 9.3e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHHCDELJ_01162 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHHCDELJ_01163 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHHCDELJ_01164 4.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHHCDELJ_01165 4.6e-52 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHHCDELJ_01166 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHHCDELJ_01167 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KHHCDELJ_01168 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHHCDELJ_01169 4.9e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHHCDELJ_01170 3.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHHCDELJ_01171 9.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHHCDELJ_01172 4.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHHCDELJ_01173 3.4e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KHHCDELJ_01174 4.6e-106 rplD J Forms part of the polypeptide exit tunnel
KHHCDELJ_01175 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHHCDELJ_01176 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KHHCDELJ_01177 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHHCDELJ_01178 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KHHCDELJ_01179 1.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHHCDELJ_01180 7.9e-123 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KHHCDELJ_01181 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHHCDELJ_01182 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHHCDELJ_01183 1.7e-31 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHHCDELJ_01184 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KHHCDELJ_01185 4.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
KHHCDELJ_01187 7.8e-08
KHHCDELJ_01188 7.8e-08
KHHCDELJ_01189 1.5e-302 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KHHCDELJ_01190 1.4e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHHCDELJ_01191 2.6e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHHCDELJ_01192 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHHCDELJ_01193 2.2e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KHHCDELJ_01194 2.8e-63 yabR J S1 RNA binding domain
KHHCDELJ_01195 1.1e-57 divIC D Septum formation initiator
KHHCDELJ_01196 2.4e-34 yabO J S4 domain protein
KHHCDELJ_01197 1.9e-275 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHHCDELJ_01198 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHHCDELJ_01199 1.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KHHCDELJ_01200 2.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KHHCDELJ_01201 2.9e-128 S (CBS) domain
KHHCDELJ_01202 1.2e-216 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHHCDELJ_01203 7.6e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KHHCDELJ_01204 3.9e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KHHCDELJ_01205 7.7e-263 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KHHCDELJ_01206 1.9e-39 rpmE2 J Ribosomal protein L31
KHHCDELJ_01207 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
KHHCDELJ_01208 3.7e-159 G Sucrose-6F-phosphate phosphohydrolase
KHHCDELJ_01209 1.1e-300 ybeC E amino acid
KHHCDELJ_01210 1.3e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHHCDELJ_01211 6.7e-44
KHHCDELJ_01212 3.7e-51
KHHCDELJ_01213 2.1e-96
KHHCDELJ_01215 2.5e-28 K NAD+ binding
KHHCDELJ_01216 5.2e-62 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHHCDELJ_01218 1.9e-30
KHHCDELJ_01219 1.6e-32 P Belongs to the major facilitator superfamily
KHHCDELJ_01220 5.4e-90 lmrB P Belongs to the major facilitator superfamily
KHHCDELJ_01221 7e-135 S B3 4 domain
KHHCDELJ_01222 1.9e-89 XK27_09675 K Acetyltransferase (GNAT) domain
KHHCDELJ_01223 2.7e-43 S Protein of unknown function (DUF3021)
KHHCDELJ_01224 2.9e-73 K LytTr DNA-binding domain
KHHCDELJ_01225 4e-148 cylB V ABC-2 type transporter
KHHCDELJ_01226 2.5e-155 cylA V ABC transporter
KHHCDELJ_01227 6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KHHCDELJ_01228 7.5e-172 K Helix-turn-helix
KHHCDELJ_01229 1.5e-135 K DNA-binding helix-turn-helix protein
KHHCDELJ_01230 6.4e-71 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KHHCDELJ_01231 5.2e-221 pbuX F xanthine permease
KHHCDELJ_01232 7e-107 S Protein of unknown function (DUF1211)
KHHCDELJ_01233 7.4e-160 msmR K AraC-like ligand binding domain
KHHCDELJ_01234 6e-141 pipD E Dipeptidase
KHHCDELJ_01235 1.9e-109 pipD E Dipeptidase
KHHCDELJ_01236 1.8e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHHCDELJ_01237 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KHHCDELJ_01238 3.3e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KHHCDELJ_01239 9.5e-68 S Domain of unknown function (DUF1934)
KHHCDELJ_01240 7.2e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
KHHCDELJ_01241 3.9e-44
KHHCDELJ_01242 3.3e-169 2.7.1.2 GK ROK family
KHHCDELJ_01243 1.2e-231 ptcC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHHCDELJ_01244 7.7e-129 K Helix-turn-helix domain, rpiR family
KHHCDELJ_01245 2.5e-56 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHHCDELJ_01246 3.9e-225 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHHCDELJ_01247 4.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHHCDELJ_01248 6.5e-118 S SLAP domain
KHHCDELJ_01250 5.2e-17 S SLAP domain
KHHCDELJ_01251 1.5e-86
KHHCDELJ_01252 2.2e-96 S SLAP domain
KHHCDELJ_01253 9.6e-89 S SLAP domain
KHHCDELJ_01254 1.4e-211 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHHCDELJ_01255 1.6e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KHHCDELJ_01256 3.5e-39 veg S Biofilm formation stimulator VEG
KHHCDELJ_01257 1.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KHHCDELJ_01258 1.6e-92 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHHCDELJ_01259 1.1e-121 tatD L hydrolase, TatD family
KHHCDELJ_01260 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHHCDELJ_01261 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
KHHCDELJ_01262 3.4e-109 S TPM domain
KHHCDELJ_01263 6.5e-92 comEB 3.5.4.12 F MafB19-like deaminase
KHHCDELJ_01264 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KHHCDELJ_01265 2.8e-28 E Belongs to the SOS response-associated peptidase family
KHHCDELJ_01266 4.9e-75 E Belongs to the SOS response-associated peptidase family
KHHCDELJ_01268 1.3e-114
KHHCDELJ_01269 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHHCDELJ_01270 2.4e-69 hsp O Belongs to the small heat shock protein (HSP20) family
KHHCDELJ_01271 1e-251 pepC 3.4.22.40 E aminopeptidase
KHHCDELJ_01272 1.9e-175 oppF P Belongs to the ABC transporter superfamily
KHHCDELJ_01273 2.2e-201 oppD P Belongs to the ABC transporter superfamily
KHHCDELJ_01274 4e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHHCDELJ_01275 1.1e-143 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KHHCDELJ_01276 7.5e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHHCDELJ_01277 4.6e-307 oppA E ABC transporter, substratebinding protein
KHHCDELJ_01278 5e-293 oppA E ABC transporter, substratebinding protein
KHHCDELJ_01279 1.2e-125 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KHHCDELJ_01280 7.2e-258 pepC 3.4.22.40 E aminopeptidase
KHHCDELJ_01282 3.3e-56
KHHCDELJ_01283 3.3e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHHCDELJ_01284 6.2e-268 S Fibronectin type III domain
KHHCDELJ_01285 0.0 XK27_08315 M Sulfatase
KHHCDELJ_01286 6.4e-108 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHHCDELJ_01287 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KHHCDELJ_01288 1.6e-102 G Aldose 1-epimerase
KHHCDELJ_01289 1.8e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHHCDELJ_01290 2.5e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHHCDELJ_01291 5.1e-105
KHHCDELJ_01292 7.4e-141
KHHCDELJ_01293 9.8e-180 S Oxidoreductase family, NAD-binding Rossmann fold
KHHCDELJ_01294 0.0 yjbQ P TrkA C-terminal domain protein
KHHCDELJ_01295 7.2e-211 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KHHCDELJ_01296 1.1e-207 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KHHCDELJ_01297 2.6e-226 S SLAP domain
KHHCDELJ_01298 2.5e-153
KHHCDELJ_01299 2.4e-256 ica2 GT2 M Glycosyl transferase family group 2
KHHCDELJ_01300 3e-60 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
KHHCDELJ_01301 7.9e-212 S SLAP domain
KHHCDELJ_01302 6.9e-11
KHHCDELJ_01303 1.9e-69
KHHCDELJ_01304 0.0 kup P Transport of potassium into the cell
KHHCDELJ_01305 3.6e-301 pepO 3.4.24.71 O Peptidase family M13
KHHCDELJ_01306 1.5e-63 pepO 3.4.24.71 O Peptidase family M13
KHHCDELJ_01307 9.5e-53 yttB EGP Major facilitator Superfamily
KHHCDELJ_01308 2.1e-137 yttB EGP Major facilitator Superfamily
KHHCDELJ_01309 1.1e-233 XK27_04775 S PAS domain
KHHCDELJ_01310 6.5e-99 S Iron-sulfur cluster assembly protein
KHHCDELJ_01311 8.1e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHHCDELJ_01312 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KHHCDELJ_01313 3.3e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
KHHCDELJ_01314 0.0 asnB 6.3.5.4 E Asparagine synthase
KHHCDELJ_01315 3.4e-274 S Calcineurin-like phosphoesterase
KHHCDELJ_01316 1.5e-83
KHHCDELJ_01317 8.6e-107 tag 3.2.2.20 L glycosylase
KHHCDELJ_01318 7.6e-149 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KHHCDELJ_01319 2.8e-132 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
KHHCDELJ_01320 2.3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KHHCDELJ_01321 1.5e-164 phnD P Phosphonate ABC transporter
KHHCDELJ_01322 2.1e-85 uspA T universal stress protein
KHHCDELJ_01323 2.2e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
KHHCDELJ_01324 1.1e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHHCDELJ_01325 1.8e-89 ntd 2.4.2.6 F Nucleoside
KHHCDELJ_01326 5.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHHCDELJ_01327 0.0 G Belongs to the glycosyl hydrolase 31 family
KHHCDELJ_01328 5.6e-160 I alpha/beta hydrolase fold
KHHCDELJ_01329 2.4e-131 yibF S overlaps another CDS with the same product name
KHHCDELJ_01330 4.8e-202 yibE S overlaps another CDS with the same product name
KHHCDELJ_01331 7.2e-90
KHHCDELJ_01332 4.7e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KHHCDELJ_01333 6.6e-229 S Cysteine-rich secretory protein family
KHHCDELJ_01334 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHHCDELJ_01335 1.4e-257 glnPH2 P ABC transporter permease
KHHCDELJ_01336 2.1e-130
KHHCDELJ_01337 1.4e-124 luxT K Bacterial regulatory proteins, tetR family
KHHCDELJ_01338 2e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHHCDELJ_01339 1.6e-76 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KHHCDELJ_01340 4.1e-46
KHHCDELJ_01341 2.9e-160 yfnA E Amino Acid
KHHCDELJ_01342 3.1e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHHCDELJ_01343 1.6e-151 yxeH S hydrolase
KHHCDELJ_01344 3.5e-154 S reductase
KHHCDELJ_01345 6.4e-66 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHHCDELJ_01346 7.7e-146 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHHCDELJ_01347 2.5e-225 patA 2.6.1.1 E Aminotransferase
KHHCDELJ_01348 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KHHCDELJ_01349 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KHHCDELJ_01350 6.5e-47 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHHCDELJ_01352 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHHCDELJ_01353 4e-49
KHHCDELJ_01354 1e-173 prmA J Ribosomal protein L11 methyltransferase
KHHCDELJ_01355 5.7e-84 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHHCDELJ_01356 5.5e-245 yjjP S Putative threonine/serine exporter
KHHCDELJ_01357 1.2e-177 citR K Putative sugar-binding domain
KHHCDELJ_01358 2.2e-54
KHHCDELJ_01359 1.3e-63 S Domain of unknown function DUF1828
KHHCDELJ_01360 7.4e-95 S UPF0397 protein
KHHCDELJ_01361 0.0 ykoD P ABC transporter, ATP-binding protein
KHHCDELJ_01362 1.5e-127 cbiQ P cobalt transport
KHHCDELJ_01363 3.3e-13
KHHCDELJ_01364 9.3e-72 yeaL S Protein of unknown function (DUF441)
KHHCDELJ_01365 9.2e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
KHHCDELJ_01366 1.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
KHHCDELJ_01367 4.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
KHHCDELJ_01368 8.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KHHCDELJ_01369 1.1e-155 ydjP I Alpha/beta hydrolase family
KHHCDELJ_01370 1.2e-274 P Sodium:sulfate symporter transmembrane region
KHHCDELJ_01371 1.2e-257 pepC 3.4.22.40 E Peptidase C1-like family
KHHCDELJ_01372 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KHHCDELJ_01373 8e-293 M domain protein
KHHCDELJ_01374 2e-266 frdC 1.3.5.4 C FAD binding domain
KHHCDELJ_01375 2e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KHHCDELJ_01376 7.6e-81 metI P ABC transporter permease
KHHCDELJ_01377 4.9e-157 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHHCDELJ_01378 5e-159 metQ1 P Belongs to the nlpA lipoprotein family
KHHCDELJ_01379 0.0 aha1 P E1-E2 ATPase
KHHCDELJ_01380 1.9e-70 aha1 P E1-E2 ATPase
KHHCDELJ_01381 5.6e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHHCDELJ_01382 6.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHHCDELJ_01383 8.1e-252 yifK E Amino acid permease
KHHCDELJ_01384 4.4e-29 2.3.1.19 K Helix-turn-helix XRE-family like proteins
KHHCDELJ_01385 1.2e-55 ansR 3.4.21.88 K Cro/C1-type HTH DNA-binding domain
KHHCDELJ_01387 5.8e-83
KHHCDELJ_01388 2.4e-11
KHHCDELJ_01389 4.3e-180 L Belongs to the 'phage' integrase family
KHHCDELJ_01391 3.3e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHHCDELJ_01392 3.5e-40 3.6.1.27 I Acid phosphatase homologues
KHHCDELJ_01393 6.3e-49 3.6.1.27 I Acid phosphatase homologues
KHHCDELJ_01394 7.1e-77 yitS S Uncharacterised protein, DegV family COG1307
KHHCDELJ_01395 1.1e-30 yitS S Uncharacterised protein, DegV family COG1307
KHHCDELJ_01396 8.1e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHHCDELJ_01397 1.3e-108 S Domain of unknown function (DUF4767)
KHHCDELJ_01398 1.6e-85 C Nitroreductase family
KHHCDELJ_01399 6.8e-156 ypbG 2.7.1.2 GK ROK family
KHHCDELJ_01400 9.5e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHHCDELJ_01401 2.4e-267 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHHCDELJ_01402 3.5e-41
KHHCDELJ_01403 4.7e-134 gmuR K UTRA
KHHCDELJ_01404 6.3e-303 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHHCDELJ_01405 1.2e-70 S Domain of unknown function (DUF3284)
KHHCDELJ_01406 4.4e-138 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHHCDELJ_01407 1.2e-80
KHHCDELJ_01408 6.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
KHHCDELJ_01409 4.5e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
KHHCDELJ_01410 2.2e-128 K UTRA domain
KHHCDELJ_01411 2.4e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHHCDELJ_01413 6e-39 S Transglycosylase associated protein
KHHCDELJ_01414 1.5e-67 alkD L DNA alkylation repair enzyme
KHHCDELJ_01415 6.1e-19 alkD L DNA alkylation repair enzyme
KHHCDELJ_01418 2.7e-10
KHHCDELJ_01419 2.3e-131
KHHCDELJ_01420 2.7e-16 adhC 1.1.1.90 C S-(hydroxymethyl)glutathione dehydrogenase activity
KHHCDELJ_01421 5.2e-178 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
KHHCDELJ_01422 4.1e-286
KHHCDELJ_01423 1.6e-80
KHHCDELJ_01424 8.6e-41 C FMN_bind
KHHCDELJ_01425 6.5e-243 I Protein of unknown function (DUF2974)
KHHCDELJ_01426 1.7e-46 I Protein of unknown function (DUF2974)
KHHCDELJ_01427 9.2e-206 pbpX1 V Beta-lactamase
KHHCDELJ_01428 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHHCDELJ_01429 5.3e-220 aspC 2.6.1.1 E Aminotransferase
KHHCDELJ_01430 3.9e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KHHCDELJ_01431 3.7e-176 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KHHCDELJ_01432 2.8e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KHHCDELJ_01433 5.7e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KHHCDELJ_01434 2.9e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KHHCDELJ_01435 2.5e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
KHHCDELJ_01436 8.9e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KHHCDELJ_01437 2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KHHCDELJ_01438 1.2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHHCDELJ_01439 3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KHHCDELJ_01440 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHHCDELJ_01441 2.2e-151
KHHCDELJ_01442 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHHCDELJ_01443 1.1e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHHCDELJ_01444 5.4e-24 rpsT J Binds directly to 16S ribosomal RNA
KHHCDELJ_01445 8.8e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
KHHCDELJ_01446 0.0 comEC S Competence protein ComEC
KHHCDELJ_01447 1.7e-72 comEA L Competence protein ComEA
KHHCDELJ_01448 7.6e-194 ylbL T Belongs to the peptidase S16 family
KHHCDELJ_01449 6.2e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHHCDELJ_01450 4.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KHHCDELJ_01451 4.3e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KHHCDELJ_01452 4.7e-211 ftsW D Belongs to the SEDS family
KHHCDELJ_01453 0.0 typA T GTP-binding protein TypA
KHHCDELJ_01454 1.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHHCDELJ_01455 3.2e-33 ykzG S Belongs to the UPF0356 family
KHHCDELJ_01456 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHHCDELJ_01457 9.3e-183 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KHHCDELJ_01458 1.1e-303 L Nuclease-related domain
KHHCDELJ_01459 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KHHCDELJ_01460 2e-103 S Repeat protein
KHHCDELJ_01461 4.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KHHCDELJ_01462 9.3e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KHHCDELJ_01463 9.8e-58 XK27_04120 S Putative amino acid metabolism
KHHCDELJ_01464 5.9e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHHCDELJ_01465 3.4e-28
KHHCDELJ_01466 8.9e-104 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KHHCDELJ_01467 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
KHHCDELJ_01468 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHHCDELJ_01469 1.9e-75 gpsB D DivIVA domain protein
KHHCDELJ_01470 8.8e-104 ylmH S S4 domain protein
KHHCDELJ_01471 7.8e-29 yggT S YGGT family
KHHCDELJ_01472 2.1e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KHHCDELJ_01473 4.2e-245 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHHCDELJ_01474 2.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KHHCDELJ_01475 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KHHCDELJ_01476 4e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHHCDELJ_01477 1.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHHCDELJ_01478 2.1e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHHCDELJ_01479 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KHHCDELJ_01480 2.4e-54 ftsL D Cell division protein FtsL
KHHCDELJ_01481 2.2e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KHHCDELJ_01482 4e-72 mraZ K Belongs to the MraZ family
KHHCDELJ_01483 3.2e-53 S Protein of unknown function (DUF3397)
KHHCDELJ_01484 8.8e-10 S Protein of unknown function (DUF4044)
KHHCDELJ_01485 7.1e-95 mreD
KHHCDELJ_01486 7.2e-150 mreC M Involved in formation and maintenance of cell shape
KHHCDELJ_01487 1.1e-176 mreB D cell shape determining protein MreB
KHHCDELJ_01488 1.2e-114 radC L DNA repair protein
KHHCDELJ_01489 8.9e-127 S Haloacid dehalogenase-like hydrolase
KHHCDELJ_01490 6.3e-205 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KHHCDELJ_01491 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KHHCDELJ_01492 2.2e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KHHCDELJ_01493 5.9e-230 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHHCDELJ_01494 1.1e-217 iscS2 2.8.1.7 E Aminotransferase class V
KHHCDELJ_01495 1.5e-292 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KHHCDELJ_01496 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHHCDELJ_01497 1.9e-83 yueI S Protein of unknown function (DUF1694)
KHHCDELJ_01498 4.2e-242 rarA L recombination factor protein RarA
KHHCDELJ_01499 4e-33
KHHCDELJ_01500 5.8e-77 uspA T universal stress protein
KHHCDELJ_01501 9.5e-217 rodA D Belongs to the SEDS family
KHHCDELJ_01502 1.5e-33 S Protein of unknown function (DUF2969)
KHHCDELJ_01503 2.5e-49 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KHHCDELJ_01504 1.9e-178 mbl D Cell shape determining protein MreB Mrl
KHHCDELJ_01505 2.6e-30 ywzB S Protein of unknown function (DUF1146)
KHHCDELJ_01506 2e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KHHCDELJ_01507 2.1e-255 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHHCDELJ_01508 9.8e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHHCDELJ_01509 2.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHHCDELJ_01510 1.5e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHHCDELJ_01511 1.7e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHHCDELJ_01512 6.6e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHHCDELJ_01513 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
KHHCDELJ_01514 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHHCDELJ_01515 1.8e-184 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KHHCDELJ_01516 7.8e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KHHCDELJ_01517 3.4e-181 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHHCDELJ_01518 1.2e-92 tdk 2.7.1.21 F thymidine kinase
KHHCDELJ_01519 2e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
KHHCDELJ_01520 9.5e-208 sip L Belongs to the 'phage' integrase family
KHHCDELJ_01521 3.2e-58 K Transcriptional
KHHCDELJ_01522 2.9e-12 S Helix-turn-helix domain
KHHCDELJ_01523 1.4e-36
KHHCDELJ_01524 8.1e-69
KHHCDELJ_01525 1.9e-33
KHHCDELJ_01526 1.6e-35
KHHCDELJ_01527 2.9e-287 S DNA primase
KHHCDELJ_01528 2e-64
KHHCDELJ_01531 1.6e-196 ampC V Beta-lactamase
KHHCDELJ_01532 9.9e-250 EGP Major facilitator Superfamily
KHHCDELJ_01533 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
KHHCDELJ_01534 5.9e-79 vanZ V VanZ like family
KHHCDELJ_01535 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHHCDELJ_01536 2.2e-123 XK27_00915 C Luciferase-like monooxygenase
KHHCDELJ_01537 1.6e-61 limB 1.14.13.107, 1.14.13.162 C Luciferase-like monooxygenase
KHHCDELJ_01538 6.2e-271 T PhoQ Sensor
KHHCDELJ_01539 2.9e-94 K Transcriptional regulatory protein, C terminal
KHHCDELJ_01540 4.9e-61 S SdpI/YhfL protein family
KHHCDELJ_01541 2.3e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
KHHCDELJ_01542 5.7e-29 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KHHCDELJ_01543 8.1e-176 patB 4.4.1.8 E Aminotransferase, class I
KHHCDELJ_01544 4.3e-121 M Protein of unknown function (DUF3737)
KHHCDELJ_01546 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHHCDELJ_01547 3e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
KHHCDELJ_01548 1.3e-86 comGF U Putative Competence protein ComGF
KHHCDELJ_01549 1e-19
KHHCDELJ_01550 2e-71
KHHCDELJ_01551 2.4e-46 comGC U competence protein ComGC
KHHCDELJ_01552 9.9e-175 comGB NU type II secretion system
KHHCDELJ_01553 1.7e-142 comGA NU Type II IV secretion system protein
KHHCDELJ_01554 7.9e-23 comGA NU Type II IV secretion system protein
KHHCDELJ_01555 2e-132 yebC K Transcriptional regulatory protein
KHHCDELJ_01556 1.9e-92 S VanZ like family
KHHCDELJ_01557 2.2e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHHCDELJ_01559 0.0 E Amino acid permease
KHHCDELJ_01560 4.2e-175 D Alpha beta
KHHCDELJ_01561 3.1e-286 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KHHCDELJ_01562 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHHCDELJ_01563 3.4e-152 licT K CAT RNA binding domain
KHHCDELJ_01564 6.7e-212 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KHHCDELJ_01565 1.2e-73 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHHCDELJ_01566 1e-120
KHHCDELJ_01567 1.3e-145 S Sucrose-6F-phosphate phosphohydrolase
KHHCDELJ_01568 1.3e-148 S hydrolase
KHHCDELJ_01569 3.9e-259 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHHCDELJ_01570 1.2e-172 ybbR S YbbR-like protein
KHHCDELJ_01571 1.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHHCDELJ_01572 1e-206 potD P ABC transporter
KHHCDELJ_01573 2.9e-132 potC P ABC transporter permease
KHHCDELJ_01574 1.1e-136 potB P ABC transporter permease
KHHCDELJ_01575 9.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KHHCDELJ_01576 2.4e-164 murB 1.3.1.98 M Cell wall formation
KHHCDELJ_01577 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
KHHCDELJ_01578 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KHHCDELJ_01579 1.8e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KHHCDELJ_01580 2.6e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHHCDELJ_01581 3.1e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
KHHCDELJ_01582 1.3e-96
KHHCDELJ_01583 9.9e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHHCDELJ_01584 3.5e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KHHCDELJ_01585 3.8e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHHCDELJ_01586 7e-80 cggR K Putative sugar-binding domain
KHHCDELJ_01587 2.7e-83 cggR K Putative sugar-binding domain
KHHCDELJ_01589 4.5e-216 ycaM E amino acid
KHHCDELJ_01590 2.4e-46 ycaM E amino acid
KHHCDELJ_01591 0.0 S SH3-like domain
KHHCDELJ_01592 4.7e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHHCDELJ_01593 6.8e-170 whiA K May be required for sporulation
KHHCDELJ_01594 8.1e-196 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KHHCDELJ_01595 2.8e-63 rapZ S Displays ATPase and GTPase activities
KHHCDELJ_01596 3.6e-91 rapZ S Displays ATPase and GTPase activities
KHHCDELJ_01597 1.1e-90 S Short repeat of unknown function (DUF308)
KHHCDELJ_01598 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KHHCDELJ_01599 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KHHCDELJ_01600 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KHHCDELJ_01601 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
KHHCDELJ_01602 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KHHCDELJ_01603 2.8e-287 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
KHHCDELJ_01604 7.2e-214 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
KHHCDELJ_01605 2.9e-223 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KHHCDELJ_01606 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KHHCDELJ_01607 1.2e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHHCDELJ_01608 6.1e-188 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KHHCDELJ_01609 1.4e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHHCDELJ_01610 5.4e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHHCDELJ_01612 3.5e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHHCDELJ_01613 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHHCDELJ_01614 5.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHHCDELJ_01615 3.1e-135 comFC S Competence protein
KHHCDELJ_01616 3.3e-247 comFA L Helicase C-terminal domain protein
KHHCDELJ_01617 9.6e-118 yvyE 3.4.13.9 S YigZ family
KHHCDELJ_01618 1.8e-212 tagO 2.7.8.33, 2.7.8.35 M transferase
KHHCDELJ_01619 8.7e-221 rny S Endoribonuclease that initiates mRNA decay
KHHCDELJ_01620 7.9e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHHCDELJ_01621 9.3e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHHCDELJ_01622 6.6e-119 ymfM S Helix-turn-helix domain
KHHCDELJ_01623 2e-132 IQ Enoyl-(Acyl carrier protein) reductase
KHHCDELJ_01624 4.5e-241 S Peptidase M16
KHHCDELJ_01625 3.5e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
KHHCDELJ_01626 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KHHCDELJ_01627 1.8e-68 WQ51_03320 S Protein of unknown function (DUF1149)
KHHCDELJ_01628 1.3e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KHHCDELJ_01629 3.2e-212 yubA S AI-2E family transporter
KHHCDELJ_01630 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
KHHCDELJ_01631 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
KHHCDELJ_01632 1.7e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KHHCDELJ_01633 2e-118 S SNARE associated Golgi protein
KHHCDELJ_01634 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KHHCDELJ_01635 8.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHHCDELJ_01636 1.6e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHHCDELJ_01637 2.3e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
KHHCDELJ_01638 9.5e-112 yjbK S CYTH
KHHCDELJ_01639 1.2e-114 yjbH Q Thioredoxin
KHHCDELJ_01640 1.2e-160 coiA 3.6.4.12 S Competence protein
KHHCDELJ_01641 8.8e-128 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KHHCDELJ_01642 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KHHCDELJ_01643 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHHCDELJ_01644 8.5e-41 ptsH G phosphocarrier protein HPR
KHHCDELJ_01645 0.0 clpE O Belongs to the ClpA ClpB family
KHHCDELJ_01646 6.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
KHHCDELJ_01647 1e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KHHCDELJ_01648 2.4e-99 hlyX S Transporter associated domain
KHHCDELJ_01649 5.2e-50 hlyX S Transporter associated domain
KHHCDELJ_01650 1.2e-71
KHHCDELJ_01651 9.1e-86
KHHCDELJ_01652 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
KHHCDELJ_01653 6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHHCDELJ_01654 1.8e-161 D Alpha beta
KHHCDELJ_01655 1.9e-46
KHHCDELJ_01656 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KHHCDELJ_01657 1.3e-218 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KHHCDELJ_01658 5.1e-215 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
KHHCDELJ_01659 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KHHCDELJ_01660 4.1e-151 yihY S Belongs to the UPF0761 family
KHHCDELJ_01661 1.1e-163 map 3.4.11.18 E Methionine Aminopeptidase
KHHCDELJ_01662 1.2e-79 fld C Flavodoxin
KHHCDELJ_01663 4.3e-89 gtcA S Teichoic acid glycosylation protein
KHHCDELJ_01664 2.5e-49 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KHHCDELJ_01665 1.8e-81 dedA 3.1.3.1 S SNARE associated Golgi protein
KHHCDELJ_01666 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHHCDELJ_01667 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHHCDELJ_01668 1.8e-213 I Acyltransferase
KHHCDELJ_01669 2e-91 I Acyltransferase
KHHCDELJ_01670 2.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KHHCDELJ_01671 7.2e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KHHCDELJ_01672 5.1e-32 yrvD S Lipopolysaccharide assembly protein A domain
KHHCDELJ_01673 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KHHCDELJ_01674 7.3e-183 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KHHCDELJ_01675 3.9e-98 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KHHCDELJ_01677 0.0 dnaE 2.7.7.7 L DNA polymerase
KHHCDELJ_01678 1.6e-76 dnaE 2.7.7.7 L DNA polymerase
KHHCDELJ_01679 7.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KHHCDELJ_01680 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KHHCDELJ_01681 5e-170 cvfB S S1 domain
KHHCDELJ_01682 1.6e-168 xerD D recombinase XerD
KHHCDELJ_01683 1.7e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHHCDELJ_01684 1.3e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHHCDELJ_01685 3.2e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHHCDELJ_01686 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KHHCDELJ_01687 5.3e-14 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHHCDELJ_01688 2.3e-35 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHHCDELJ_01689 9.7e-36 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHHCDELJ_01690 1.1e-46 M Lysin motif
KHHCDELJ_01691 5.5e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KHHCDELJ_01692 2.3e-202 rpsA 1.17.7.4 J Ribosomal protein S1
KHHCDELJ_01693 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KHHCDELJ_01694 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KHHCDELJ_01695 2.1e-230 S Tetratricopeptide repeat protein
KHHCDELJ_01696 4.2e-59 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHHCDELJ_01697 2.5e-36 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHHCDELJ_01698 1.1e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KHHCDELJ_01699 2.2e-106 hlyIII S protein, hemolysin III
KHHCDELJ_01700 3.6e-74 DegV S Uncharacterised protein, DegV family COG1307
KHHCDELJ_01701 2.1e-61 DegV S Uncharacterised protein, DegV family COG1307
KHHCDELJ_01702 2.7e-35 yozE S Belongs to the UPF0346 family
KHHCDELJ_01703 3.9e-282 yjcE P Sodium proton antiporter
KHHCDELJ_01704 1e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHHCDELJ_01705 1.1e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHHCDELJ_01706 3.6e-157 dprA LU DNA protecting protein DprA
KHHCDELJ_01707 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHHCDELJ_01708 1.8e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KHHCDELJ_01709 7.3e-169 xerC D Phage integrase, N-terminal SAM-like domain
KHHCDELJ_01710 1.1e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KHHCDELJ_01711 1.7e-233 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KHHCDELJ_01712 2.7e-179 lacX 5.1.3.3 G Aldose 1-epimerase
KHHCDELJ_01713 1.5e-65
KHHCDELJ_01714 9.4e-198 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHHCDELJ_01715 8e-16 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHHCDELJ_01716 3.2e-158 S Alpha/beta hydrolase of unknown function (DUF915)
KHHCDELJ_01717 1.4e-150 xerD L Phage integrase, N-terminal SAM-like domain
KHHCDELJ_01718 3.5e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHHCDELJ_01719 1.1e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHHCDELJ_01720 6.9e-275 pepV 3.5.1.18 E dipeptidase PepV
KHHCDELJ_01721 5.3e-286 E Amino acid permease
KHHCDELJ_01722 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
KHHCDELJ_01723 5.3e-144 ynbB 4.4.1.1 P aluminum resistance
KHHCDELJ_01724 7.3e-94 ynbB 4.4.1.1 P aluminum resistance
KHHCDELJ_01725 3.9e-119 ktrA P domain protein
KHHCDELJ_01726 4e-240 ktrB P Potassium uptake protein
KHHCDELJ_01727 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KHHCDELJ_01728 1.7e-81 C Flavodoxin
KHHCDELJ_01729 0.0 uvrA3 L excinuclease ABC, A subunit
KHHCDELJ_01730 5.9e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KHHCDELJ_01731 1.8e-113 3.6.1.27 I Acid phosphatase homologues
KHHCDELJ_01732 4.5e-67 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KHHCDELJ_01733 1.9e-208 pbpX1 V Beta-lactamase
KHHCDELJ_01734 1.5e-155 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KHHCDELJ_01735 3.1e-93 S ECF-type riboflavin transporter, S component
KHHCDELJ_01736 2.1e-216 S Putative peptidoglycan binding domain
KHHCDELJ_01737 2.7e-52
KHHCDELJ_01738 5.7e-173
KHHCDELJ_01739 0.0 treB 2.7.1.208, 2.7.1.211 G phosphotransferase system
KHHCDELJ_01740 2.9e-128 treR K UTRA
KHHCDELJ_01741 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
KHHCDELJ_01742 2.8e-128 M Glycosyl transferases group 1
KHHCDELJ_01743 3.8e-99 UW LPXTG-motif cell wall anchor domain protein
KHHCDELJ_01744 2.4e-164 M domain protein
KHHCDELJ_01745 2.6e-21 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
KHHCDELJ_01746 0.0 UW LPXTG-motif cell wall anchor domain protein
KHHCDELJ_01747 0.0 UW LPXTG-motif cell wall anchor domain protein
KHHCDELJ_01748 3.4e-214 UW LPXTG-motif cell wall anchor domain protein
KHHCDELJ_01749 4.6e-81 UW LPXTG-motif cell wall anchor domain protein
KHHCDELJ_01750 1.7e-13 UW LPXTG-motif cell wall anchor domain protein
KHHCDELJ_01751 1.2e-28 K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
KHHCDELJ_01752 8.8e-164 rocF 3.5.3.1, 3.5.3.11 E Arginase family
KHHCDELJ_01753 2.1e-114 ylbE GM NAD dependent epimerase dehydratase family protein
KHHCDELJ_01754 6.6e-159 K Transcriptional regulator
KHHCDELJ_01755 2.9e-167 S Oxidoreductase, aldo keto reductase family protein
KHHCDELJ_01756 4.3e-166 akr5f 1.1.1.346 S reductase
KHHCDELJ_01757 2.7e-165 yvgN C Aldo keto reductase
KHHCDELJ_01758 4.1e-217 S SLAP domain
KHHCDELJ_01759 4.1e-103 yyaR K Acetyltransferase (GNAT) domain
KHHCDELJ_01762 6.8e-104
KHHCDELJ_01763 6.8e-78 K Transcriptional regulator
KHHCDELJ_01764 1.9e-245 brnQ U Component of the transport system for branched-chain amino acids
KHHCDELJ_01765 3e-164 S reductase
KHHCDELJ_01766 1.3e-170
KHHCDELJ_01767 4.2e-33 K Transcriptional regulator
KHHCDELJ_01768 9.3e-113 papP P ABC transporter, permease protein
KHHCDELJ_01769 2.2e-77 P ABC transporter permease
KHHCDELJ_01770 3.5e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KHHCDELJ_01771 7.7e-160 cjaA ET ABC transporter substrate-binding protein
KHHCDELJ_01772 8.3e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KHHCDELJ_01773 8.7e-110 5.4.2.11 G Phosphoglycerate mutase family
KHHCDELJ_01774 3.4e-174 4.1.1.45 S Amidohydrolase
KHHCDELJ_01775 1.1e-29
KHHCDELJ_01776 2.5e-109
KHHCDELJ_01777 4.9e-108
KHHCDELJ_01778 1.3e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
KHHCDELJ_01779 2.3e-215 ynfM EGP Major facilitator Superfamily
KHHCDELJ_01780 1e-153 K Bacterial regulatory helix-turn-helix protein, lysR family
KHHCDELJ_01781 8.2e-119 3.6.1.55 F NUDIX domain
KHHCDELJ_01782 1.3e-76
KHHCDELJ_01783 3.6e-87 FG HIT domain
KHHCDELJ_01784 1.1e-62
KHHCDELJ_01785 3.7e-93 rimL J Acetyltransferase (GNAT) domain
KHHCDELJ_01786 1.1e-101 S Alpha/beta hydrolase family
KHHCDELJ_01787 9.7e-101
KHHCDELJ_01788 1.3e-71
KHHCDELJ_01789 1.5e-146 2.4.2.3 F Phosphorylase superfamily
KHHCDELJ_01790 6.2e-108 5.4.2.11 G Phosphoglycerate mutase family
KHHCDELJ_01791 5.1e-147 2.4.2.3 F Phosphorylase superfamily
KHHCDELJ_01792 6e-85 2.4.2.3 F Phosphorylase superfamily
KHHCDELJ_01793 1.8e-50 2.4.2.3 F Phosphorylase superfamily
KHHCDELJ_01794 1.4e-112 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KHHCDELJ_01795 7.2e-36
KHHCDELJ_01796 8.3e-53 mleP S Sodium Bile acid symporter family
KHHCDELJ_01797 1.5e-91
KHHCDELJ_01798 1.3e-38
KHHCDELJ_01799 1.8e-167 mleR K LysR family
KHHCDELJ_01800 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KHHCDELJ_01801 1.9e-101 ltrA S Bacterial low temperature requirement A protein (LtrA)
KHHCDELJ_01802 4.4e-244 yrvN L AAA C-terminal domain
KHHCDELJ_01803 2.9e-195 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHHCDELJ_01804 2.9e-71 S L,D-transpeptidase catalytic domain
KHHCDELJ_01805 4.7e-218 2.1.1.14 E methionine synthase, vitamin-B12 independent
KHHCDELJ_01806 2.3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHHCDELJ_01807 7.9e-67 L nuclease
KHHCDELJ_01808 3.3e-155 F DNA/RNA non-specific endonuclease
KHHCDELJ_01809 4.3e-115 ywnB S NAD(P)H-binding
KHHCDELJ_01810 1.7e-238 steT E amino acid
KHHCDELJ_01811 4.4e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KHHCDELJ_01812 2.4e-40 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KHHCDELJ_01813 2.2e-148 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KHHCDELJ_01814 0.0 ppc 4.1.1.31 C phosphoenolpyruvate carboxylase activity
KHHCDELJ_01815 0.0
KHHCDELJ_01816 0.0
KHHCDELJ_01817 0.0
KHHCDELJ_01818 3.5e-174 yobV1 K WYL domain
KHHCDELJ_01819 3.1e-83 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
KHHCDELJ_01820 2.6e-146 IQ reductase
KHHCDELJ_01821 7.1e-55 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
KHHCDELJ_01822 7.2e-115 tas C Aldo/keto reductase family
KHHCDELJ_01823 2.9e-60 C aldo keto reductase
KHHCDELJ_01824 3.6e-146 glcU U ribose uptake protein RbsU
KHHCDELJ_01825 1e-20 C Flavodoxin
KHHCDELJ_01827 2.7e-98 fldA C Flavodoxin
KHHCDELJ_01828 7.7e-100 P esterase
KHHCDELJ_01829 2.4e-261 gor 1.8.1.7 C Glutathione reductase
KHHCDELJ_01830 4.1e-23
KHHCDELJ_01831 4.2e-141 fldA C Flavodoxin
KHHCDELJ_01832 7.8e-97 S LexA-binding, inner membrane-associated putative hydrolase
KHHCDELJ_01833 2.3e-14 C Flavodoxin
KHHCDELJ_01834 2.6e-149 P FAD-binding domain
KHHCDELJ_01835 3.3e-77 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KHHCDELJ_01837 3e-251 yagE E amino acid
KHHCDELJ_01838 1.3e-12 S Alpha beta hydrolase
KHHCDELJ_01839 5e-44 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHHCDELJ_01840 9.2e-17 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KHHCDELJ_01841 2.2e-18 magIII L Base excision DNA repair protein, HhH-GPD family
KHHCDELJ_01842 1.9e-168 MA20_14895 S Conserved hypothetical protein 698
KHHCDELJ_01843 7e-101
KHHCDELJ_01844 1.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHHCDELJ_01845 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHHCDELJ_01846 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHHCDELJ_01847 6.6e-184 K Transcriptional regulator
KHHCDELJ_01848 2.3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
KHHCDELJ_01849 1.7e-113 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHHCDELJ_01850 1.2e-39 K Helix-turn-helix domain
KHHCDELJ_01851 1.1e-127 yoaK S Protein of unknown function (DUF1275)
KHHCDELJ_01852 8.2e-66 fic D Fic/DOC family
KHHCDELJ_01854 1.5e-286 V ABC-type multidrug transport system, ATPase and permease components
KHHCDELJ_01855 2.3e-287 V ABC-type multidrug transport system, ATPase and permease components
KHHCDELJ_01856 1e-213 EGP Transmembrane secretion effector
KHHCDELJ_01857 3.9e-84 K transcriptional
KHHCDELJ_01858 3.3e-58 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KHHCDELJ_01860 4.3e-200 M Glycosyl hydrolases family 25
KHHCDELJ_01861 2.4e-107 XK27_00160 S Domain of unknown function (DUF5052)
KHHCDELJ_01862 1.5e-91 adk 2.7.4.3 F topology modulation protein
KHHCDELJ_01863 3.1e-59
KHHCDELJ_01864 8.4e-196 xerS L Belongs to the 'phage' integrase family
KHHCDELJ_01865 2e-55 degV S EDD domain protein, DegV family
KHHCDELJ_01866 2.3e-81 degV S EDD domain protein, DegV family
KHHCDELJ_01867 9e-66
KHHCDELJ_01868 0.0 FbpA K Fibronectin-binding protein
KHHCDELJ_01869 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
KHHCDELJ_01870 3e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KHHCDELJ_01871 3.2e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KHHCDELJ_01872 1.1e-86 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHHCDELJ_01873 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KHHCDELJ_01874 7.2e-244 cpdA S Calcineurin-like phosphoesterase
KHHCDELJ_01875 5.4e-145 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KHHCDELJ_01876 6.7e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KHHCDELJ_01877 9.4e-106 ypsA S Belongs to the UPF0398 family
KHHCDELJ_01878 7.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KHHCDELJ_01879 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KHHCDELJ_01880 1.5e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHHCDELJ_01881 5.7e-115 dnaD L DnaD domain protein
KHHCDELJ_01882 2.4e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KHHCDELJ_01883 1.4e-89 ypmB S Protein conserved in bacteria
KHHCDELJ_01884 8.5e-229 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KHHCDELJ_01885 2.2e-301 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KHHCDELJ_01886 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KHHCDELJ_01887 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KHHCDELJ_01888 6.6e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
KHHCDELJ_01889 4.1e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KHHCDELJ_01890 8.4e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KHHCDELJ_01891 4.2e-189 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KHHCDELJ_01892 5.2e-145 K SIS domain
KHHCDELJ_01893 3.2e-83 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KHHCDELJ_01894 1.3e-107 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
KHHCDELJ_01895 4.4e-55 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
KHHCDELJ_01896 4.6e-216 iscS 2.8.1.7 E Aminotransferase class V
KHHCDELJ_01897 1.1e-267 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
KHHCDELJ_01898 6.5e-134
KHHCDELJ_01899 4.1e-141
KHHCDELJ_01900 8.9e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KHHCDELJ_01901 2.2e-27
KHHCDELJ_01902 6.8e-131
KHHCDELJ_01903 4e-145
KHHCDELJ_01904 3.9e-132
KHHCDELJ_01905 1.1e-122 skfE V ATPases associated with a variety of cellular activities
KHHCDELJ_01906 8e-61 yvoA_1 K Transcriptional regulator, GntR family
KHHCDELJ_01907 1.3e-245 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KHHCDELJ_01908 7.7e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHHCDELJ_01909 1.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
KHHCDELJ_01910 5.6e-82 mutT 3.6.1.55 F NUDIX domain
KHHCDELJ_01911 1.1e-126 S Peptidase family M23
KHHCDELJ_01912 1.4e-198 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHHCDELJ_01913 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHHCDELJ_01914 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KHHCDELJ_01915 2.3e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KHHCDELJ_01916 3e-134 recO L Involved in DNA repair and RecF pathway recombination
KHHCDELJ_01917 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHHCDELJ_01918 7.9e-99 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHHCDELJ_01919 1.3e-176 phoH T phosphate starvation-inducible protein PhoH
KHHCDELJ_01920 6.5e-70 yqeY S YqeY-like protein
KHHCDELJ_01921 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KHHCDELJ_01922 2e-152 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KHHCDELJ_01923 1.3e-95 S Peptidase family M23
KHHCDELJ_01924 2.8e-110 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHHCDELJ_01925 2.2e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHHCDELJ_01926 4.8e-122
KHHCDELJ_01927 4.8e-162 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KHHCDELJ_01928 1.3e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KHHCDELJ_01929 6.4e-287 thrC 4.2.3.1 E Threonine synthase
KHHCDELJ_01930 9.4e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
KHHCDELJ_01931 1.5e-269 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KHHCDELJ_01932 3.5e-33 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
KHHCDELJ_01933 1.1e-18 yjgN S Bacterial protein of unknown function (DUF898)
KHHCDELJ_01934 2.8e-103 lacA 2.3.1.79 S Transferase hexapeptide repeat
KHHCDELJ_01935 0.0
KHHCDELJ_01936 2e-10
KHHCDELJ_01937 4.5e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KHHCDELJ_01938 6.4e-201 brnQ U Component of the transport system for branched-chain amino acids
KHHCDELJ_01939 1.3e-295
KHHCDELJ_01940 1.1e-121 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
KHHCDELJ_01941 1.3e-99
KHHCDELJ_01942 2.2e-108 K LysR substrate binding domain
KHHCDELJ_01943 3.7e-15
KHHCDELJ_01944 4.8e-229 S Sterol carrier protein domain
KHHCDELJ_01945 4.8e-99 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
KHHCDELJ_01946 3.2e-74 lysR5 K LysR substrate binding domain
KHHCDELJ_01947 4.9e-70 lysR5 K LysR substrate binding domain
KHHCDELJ_01948 6.1e-82 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
KHHCDELJ_01949 4.7e-311 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
KHHCDELJ_01950 1.8e-87 3.4.21.96 S SLAP domain
KHHCDELJ_01951 7e-245 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHHCDELJ_01952 4.6e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KHHCDELJ_01953 1.6e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KHHCDELJ_01954 1.1e-211 S Bacterial protein of unknown function (DUF871)
KHHCDELJ_01955 4.7e-151 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KHHCDELJ_01957 2.9e-78 K Acetyltransferase (GNAT) domain
KHHCDELJ_01958 3.7e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHHCDELJ_01959 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KHHCDELJ_01960 1.4e-87 srtA 3.4.22.70 M sortase family
KHHCDELJ_01961 9.2e-59 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHHCDELJ_01962 1.7e-207 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHHCDELJ_01963 4.1e-37 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHHCDELJ_01964 7.8e-200 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KHHCDELJ_01965 0.0 dnaK O Heat shock 70 kDa protein
KHHCDELJ_01966 1.9e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHHCDELJ_01967 1.7e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KHHCDELJ_01968 2.5e-283 lsa S ABC transporter
KHHCDELJ_01969 5.2e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KHHCDELJ_01970 1e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHHCDELJ_01971 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHHCDELJ_01972 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHHCDELJ_01973 8.4e-48 rplGA J ribosomal protein
KHHCDELJ_01974 1.4e-47 ylxR K Protein of unknown function (DUF448)
KHHCDELJ_01975 3.3e-198 nusA K Participates in both transcription termination and antitermination
KHHCDELJ_01976 7.2e-83 rimP J Required for maturation of 30S ribosomal subunits
KHHCDELJ_01977 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHHCDELJ_01978 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHHCDELJ_01979 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KHHCDELJ_01980 2.6e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KHHCDELJ_01981 1.7e-145 cdsA 2.7.7.41 I Belongs to the CDS family
KHHCDELJ_01982 9.3e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHHCDELJ_01983 8.7e-88 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KHHCDELJ_01984 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KHHCDELJ_01985 2.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHHCDELJ_01986 1.1e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
KHHCDELJ_01987 1.3e-198 yabB 2.1.1.223 L Methyltransferase small domain
KHHCDELJ_01988 2.1e-71 plsC 2.3.1.51 I Acyltransferase
KHHCDELJ_01989 1e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KHHCDELJ_01990 0.0 pepO 3.4.24.71 O Peptidase family M13
KHHCDELJ_01991 3.6e-292 mdlB V ABC transporter
KHHCDELJ_01992 0.0 mdlA V ABC transporter
KHHCDELJ_01993 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
KHHCDELJ_01994 1.1e-37 ynzC S UPF0291 protein
KHHCDELJ_01995 1.5e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHHCDELJ_01996 3.1e-144 E GDSL-like Lipase/Acylhydrolase family
KHHCDELJ_01997 4.6e-57 ung2 3.2.2.27 L Uracil-DNA glycosylase
KHHCDELJ_01998 1.4e-54 ung2 3.2.2.27 L Uracil-DNA glycosylase
KHHCDELJ_01999 3.4e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KHHCDELJ_02000 8e-288 S Bacterial membrane protein, YfhO
KHHCDELJ_02001 1.1e-69 2.4.1.83 GT2 S GtrA-like protein
KHHCDELJ_02002 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KHHCDELJ_02003 5e-128 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KHHCDELJ_02004 4.7e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHHCDELJ_02005 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KHHCDELJ_02006 2.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHHCDELJ_02007 1.6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHHCDELJ_02008 3.2e-259 yfnA E amino acid
KHHCDELJ_02009 2.8e-67
KHHCDELJ_02010 2.5e-288 pipD E Dipeptidase
KHHCDELJ_02011 2.1e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KHHCDELJ_02012 0.0 smc D Required for chromosome condensation and partitioning
KHHCDELJ_02013 4.6e-88 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)