ORF_ID e_value Gene_name EC_number CAZy COGs Description
MEGKGOFH_00005 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_00006 0.0 vicK 2.7.13.3 T Histidine kinase
MEGKGOFH_00007 3.4e-258 yycH S protein conserved in bacteria
MEGKGOFH_00008 1.8e-153 yycI S protein conserved in bacteria
MEGKGOFH_00009 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MEGKGOFH_00010 5.6e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MEGKGOFH_00011 1.1e-17 S Peptidase propeptide and YPEB domain
MEGKGOFH_00012 3e-74 S Peptidase propeptide and YPEB domain
MEGKGOFH_00013 5.8e-94 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_00014 1.1e-171 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
MEGKGOFH_00015 1.3e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MEGKGOFH_00016 3.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MEGKGOFH_00017 1.3e-260 rocE E amino acid
MEGKGOFH_00018 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MEGKGOFH_00020 1.6e-189 S aspartate phosphatase
MEGKGOFH_00021 2.6e-85 yycN 2.3.1.128 K Acetyltransferase
MEGKGOFH_00022 2.9e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MEGKGOFH_00023 4.6e-208 yycP
MEGKGOFH_00024 1.7e-30 yycQ S Protein of unknown function (DUF2651)
MEGKGOFH_00026 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MEGKGOFH_00027 1.4e-66
MEGKGOFH_00028 1.1e-09 S YyzF-like protein
MEGKGOFH_00029 2.6e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEGKGOFH_00030 2.1e-81 uxuA 4.2.1.8 S AIPR protein
MEGKGOFH_00031 2.8e-104 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MEGKGOFH_00032 1e-13 2.7.7.9 K Helix-turn-helix XRE-family like proteins
MEGKGOFH_00033 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MEGKGOFH_00034 4.9e-12
MEGKGOFH_00035 3.5e-126 yydK K Transcriptional regulator
MEGKGOFH_00036 2.6e-19 bglF G phosphotransferase system
MEGKGOFH_00037 2.2e-12 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MEGKGOFH_00038 1.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEGKGOFH_00039 3.8e-287 ahpF O Alkyl hydroperoxide reductase
MEGKGOFH_00040 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MEGKGOFH_00041 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEGKGOFH_00042 7.7e-231 gntP EG COG2610 H gluconate symporter and related permeases
MEGKGOFH_00043 1.1e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MEGKGOFH_00044 7.3e-127 gntR K transcriptional
MEGKGOFH_00045 7.3e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MEGKGOFH_00046 2.3e-190 yxaB GM Polysaccharide pyruvyl transferase
MEGKGOFH_00047 8.2e-111 yxaC M effector of murein hydrolase
MEGKGOFH_00048 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
MEGKGOFH_00049 9.5e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGKGOFH_00050 2.7e-100 yxaF K Transcriptional regulator
MEGKGOFH_00051 5.6e-194 yxaG 1.13.11.24 S AraC-like ligand binding domain
MEGKGOFH_00052 2.4e-223 P Protein of unknown function (DUF418)
MEGKGOFH_00053 1.4e-75 yxaI S membrane protein domain
MEGKGOFH_00054 4.3e-63 S Family of unknown function (DUF5391)
MEGKGOFH_00055 6.8e-93 S PQQ-like domain
MEGKGOFH_00056 5.2e-54 yxaM U MFS_1 like family
MEGKGOFH_00057 1.9e-142 yxaM U MFS_1 like family
MEGKGOFH_00058 0.0 asnB 6.3.5.4 E Asparagine synthase
MEGKGOFH_00059 1.1e-86 yxnB
MEGKGOFH_00060 1.9e-43 S Coenzyme PQQ synthesis protein D (PqqD)
MEGKGOFH_00061 6.2e-126 yxbB Q Met-10+ like-protein
MEGKGOFH_00062 6.5e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
MEGKGOFH_00063 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
MEGKGOFH_00064 2.9e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MEGKGOFH_00065 1.6e-208 yxbF K Bacterial regulatory proteins, tetR family
MEGKGOFH_00066 1.2e-149 IQ Enoyl-(Acyl carrier protein) reductase
MEGKGOFH_00068 0.0 htpG O Molecular chaperone. Has ATPase activity
MEGKGOFH_00069 2.1e-244 csbC EGP Major facilitator Superfamily
MEGKGOFH_00070 8.3e-48 yxcD S Protein of unknown function (DUF2653)
MEGKGOFH_00072 8.3e-176 iolS C Aldo keto reductase
MEGKGOFH_00073 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MEGKGOFH_00074 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEGKGOFH_00075 1.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MEGKGOFH_00076 3.5e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MEGKGOFH_00077 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MEGKGOFH_00078 5.7e-174 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MEGKGOFH_00079 1.6e-233 iolF EGP Major facilitator Superfamily
MEGKGOFH_00080 1.4e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MEGKGOFH_00081 8.6e-167 iolH G Xylose isomerase-like TIM barrel
MEGKGOFH_00082 1.2e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MEGKGOFH_00083 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MEGKGOFH_00084 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_00085 2.2e-179 T PhoQ Sensor
MEGKGOFH_00086 8e-140 yxdL V ABC transporter, ATP-binding protein
MEGKGOFH_00087 0.0 yxdM V ABC transporter (permease)
MEGKGOFH_00088 1.5e-58 yxeA S Protein of unknown function (DUF1093)
MEGKGOFH_00089 2.3e-176 fhuD P ABC transporter
MEGKGOFH_00090 5.8e-23
MEGKGOFH_00091 5.6e-16 yxeD
MEGKGOFH_00092 1.3e-20 yxeE
MEGKGOFH_00095 1.8e-150 yidA S hydrolases of the HAD superfamily
MEGKGOFH_00096 4.4e-183 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MEGKGOFH_00097 4.9e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEGKGOFH_00098 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEGKGOFH_00099 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
MEGKGOFH_00100 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
MEGKGOFH_00101 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MEGKGOFH_00102 8e-213 yxeP 3.5.1.47 E hydrolase activity
MEGKGOFH_00103 1.1e-250 yxeQ S MmgE/PrpD family
MEGKGOFH_00104 1.3e-180 eutH E Ethanolamine utilisation protein, EutH
MEGKGOFH_00105 2e-152 yxxB S Domain of Unknown Function (DUF1206)
MEGKGOFH_00106 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MEGKGOFH_00107 2.9e-114 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MEGKGOFH_00108 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MEGKGOFH_00109 7.9e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MEGKGOFH_00110 2.8e-239 lysP E amino acid
MEGKGOFH_00111 1.8e-178 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MEGKGOFH_00113 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MEGKGOFH_00114 1.3e-282 hutH 4.3.1.3 E Histidine ammonia-lyase
MEGKGOFH_00115 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MEGKGOFH_00117 2.1e-279 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MEGKGOFH_00119 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MEGKGOFH_00120 1.2e-260 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEGKGOFH_00121 9.2e-72 yxiE T Belongs to the universal stress protein A family
MEGKGOFH_00122 5.5e-34 S Sporulation delaying protein SdpA
MEGKGOFH_00123 8e-89
MEGKGOFH_00124 7.2e-13
MEGKGOFH_00125 3.6e-62 K helix_turn_helix, mercury resistance
MEGKGOFH_00126 1.3e-18
MEGKGOFH_00127 3.6e-163 yxxF EG EamA-like transporter family
MEGKGOFH_00128 0.0 wapA M COG3209 Rhs family protein
MEGKGOFH_00132 4.8e-42 yxiG
MEGKGOFH_00133 5.3e-21
MEGKGOFH_00134 8.3e-61
MEGKGOFH_00135 6.3e-54 yxiI S Protein of unknown function (DUF2716)
MEGKGOFH_00136 1.9e-41 yxiJ S YxiJ-like protein
MEGKGOFH_00139 1.4e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MEGKGOFH_00140 3.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MEGKGOFH_00141 1.9e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
MEGKGOFH_00142 1.2e-110
MEGKGOFH_00143 8.3e-151 licT K transcriptional antiterminator
MEGKGOFH_00144 3.3e-143 exoK GH16 M licheninase activity
MEGKGOFH_00145 6.6e-224 citH C Citrate transporter
MEGKGOFH_00146 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MEGKGOFH_00147 3e-47 yxiS
MEGKGOFH_00148 1.5e-102 T Domain of unknown function (DUF4163)
MEGKGOFH_00149 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MEGKGOFH_00150 1.9e-158 rlmA 2.1.1.187 Q Methyltransferase domain
MEGKGOFH_00151 2.9e-252 yxjC EG COG2610 H gluconate symporter and related permeases
MEGKGOFH_00152 6.9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MEGKGOFH_00153 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MEGKGOFH_00154 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MEGKGOFH_00155 1.3e-210 yxjG 2.1.1.14 E Methionine synthase
MEGKGOFH_00156 5.7e-219 yxjG 2.1.1.14 E Methionine synthase
MEGKGOFH_00157 7.1e-86 yxjI S LURP-one-related
MEGKGOFH_00160 2.3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MEGKGOFH_00161 3.4e-115 K helix_turn_helix, Lux Regulon
MEGKGOFH_00162 1.3e-189 yxjM T Signal transduction histidine kinase
MEGKGOFH_00163 8.1e-70 S Protein of unknown function (DUF1453)
MEGKGOFH_00164 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MEGKGOFH_00165 1.4e-73 yxkC S Domain of unknown function (DUF4352)
MEGKGOFH_00166 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEGKGOFH_00167 8.2e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEGKGOFH_00168 1.6e-163 lrp QT PucR C-terminal helix-turn-helix domain
MEGKGOFH_00169 5.9e-205 msmK P Belongs to the ABC transporter superfamily
MEGKGOFH_00170 4.7e-154 yxkH G Polysaccharide deacetylase
MEGKGOFH_00172 1.4e-309 3.4.24.84 O Peptidase family M48
MEGKGOFH_00173 2.1e-228 cimH C COG3493 Na citrate symporter
MEGKGOFH_00174 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
MEGKGOFH_00175 3.8e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MEGKGOFH_00176 0.0 cydD V ATP-binding
MEGKGOFH_00177 0.0 cydD V ATP-binding protein
MEGKGOFH_00178 1.6e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEGKGOFH_00179 1.9e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MEGKGOFH_00180 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MEGKGOFH_00181 3.9e-48 yxlC S Family of unknown function (DUF5345)
MEGKGOFH_00182 1.2e-31
MEGKGOFH_00183 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
MEGKGOFH_00184 8.2e-165 yxlF V ABC transporter, ATP-binding protein
MEGKGOFH_00185 4.4e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MEGKGOFH_00186 7.1e-212 yxlH EGP Major facilitator Superfamily
MEGKGOFH_00187 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MEGKGOFH_00188 2.9e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MEGKGOFH_00189 1.1e-19 yxzF
MEGKGOFH_00190 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MEGKGOFH_00191 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MEGKGOFH_00192 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEGKGOFH_00193 5.6e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MEGKGOFH_00194 9.2e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MEGKGOFH_00195 3.4e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MEGKGOFH_00196 4.3e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGKGOFH_00197 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MEGKGOFH_00198 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGKGOFH_00199 1.2e-232 dltB M membrane protein involved in D-alanine export
MEGKGOFH_00200 4.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGKGOFH_00201 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MEGKGOFH_00202 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
MEGKGOFH_00203 3e-130 ynfM EGP Major facilitator Superfamily
MEGKGOFH_00204 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
MEGKGOFH_00205 3e-92 K Helix-turn-helix XRE-family like proteins
MEGKGOFH_00206 5.2e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MEGKGOFH_00207 2.9e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEGKGOFH_00208 8.9e-87 ywaE K Transcriptional regulator
MEGKGOFH_00209 1.5e-124 ywaF S Integral membrane protein
MEGKGOFH_00210 1.3e-167 gspA M General stress
MEGKGOFH_00211 4e-153 sacY K transcriptional antiterminator
MEGKGOFH_00212 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MEGKGOFH_00213 2.1e-36 ysfB KT regulator
MEGKGOFH_00214 5.8e-32 sspI S Belongs to the SspI family
MEGKGOFH_00215 2.8e-129 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEGKGOFH_00216 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEGKGOFH_00217 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEGKGOFH_00218 5.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEGKGOFH_00219 5.8e-18 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MEGKGOFH_00220 7.3e-14 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MEGKGOFH_00221 1.3e-85 cvpA S membrane protein, required for colicin V production
MEGKGOFH_00222 0.0 polX L COG1796 DNA polymerase IV (family X)
MEGKGOFH_00223 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEGKGOFH_00224 7.3e-68 yshE S membrane
MEGKGOFH_00225 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MEGKGOFH_00226 2.7e-100 fadR K Transcriptional regulator
MEGKGOFH_00227 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MEGKGOFH_00228 4.5e-135 etfB C Electron transfer flavoprotein
MEGKGOFH_00229 2.1e-177 etfA C Electron transfer flavoprotein
MEGKGOFH_00231 1.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MEGKGOFH_00232 2e-52 trxA O Belongs to the thioredoxin family
MEGKGOFH_00233 1.2e-73 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEGKGOFH_00234 7.8e-216 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEGKGOFH_00235 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MEGKGOFH_00236 1.2e-79 yslB S Protein of unknown function (DUF2507)
MEGKGOFH_00237 2.4e-107 sdhC C succinate dehydrogenase
MEGKGOFH_00238 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MEGKGOFH_00239 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MEGKGOFH_00240 5.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MEGKGOFH_00241 3.3e-30 gerE K Transcriptional regulator
MEGKGOFH_00242 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MEGKGOFH_00243 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MEGKGOFH_00244 2.9e-196 gerM S COG5401 Spore germination protein
MEGKGOFH_00245 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MEGKGOFH_00246 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEGKGOFH_00247 1.4e-92 ysnB S Phosphoesterase
MEGKGOFH_00249 9.1e-134 ysnF S protein conserved in bacteria
MEGKGOFH_00250 7.6e-82 ysnE K acetyltransferase
MEGKGOFH_00252 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MEGKGOFH_00253 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
MEGKGOFH_00254 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MEGKGOFH_00255 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MEGKGOFH_00256 1.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MEGKGOFH_00257 7e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEGKGOFH_00258 2.6e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MEGKGOFH_00259 5.1e-187 ysoA H Tetratricopeptide repeat
MEGKGOFH_00260 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEGKGOFH_00261 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEGKGOFH_00262 3.4e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MEGKGOFH_00263 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MEGKGOFH_00264 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MEGKGOFH_00265 1.4e-89 ysxD
MEGKGOFH_00266 1.8e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MEGKGOFH_00267 3.6e-146 hemX O cytochrome C
MEGKGOFH_00268 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MEGKGOFH_00269 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MEGKGOFH_00270 1.4e-181 hemB 4.2.1.24 H Belongs to the ALAD family
MEGKGOFH_00271 1.6e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MEGKGOFH_00272 1.6e-220 spoVID M stage VI sporulation protein D
MEGKGOFH_00273 1.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MEGKGOFH_00274 1.6e-25
MEGKGOFH_00275 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEGKGOFH_00276 3.6e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MEGKGOFH_00277 1.7e-83 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MEGKGOFH_00278 4.9e-166 spoIIB S Sporulation related domain
MEGKGOFH_00279 2.4e-101 maf D septum formation protein Maf
MEGKGOFH_00280 1.3e-125 radC E Belongs to the UPF0758 family
MEGKGOFH_00281 1.8e-184 mreB D Rod shape-determining protein MreB
MEGKGOFH_00282 2.8e-157 mreC M Involved in formation and maintenance of cell shape
MEGKGOFH_00283 1.4e-84 mreD M shape-determining protein
MEGKGOFH_00284 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MEGKGOFH_00285 2.5e-144 minD D Belongs to the ParA family
MEGKGOFH_00286 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MEGKGOFH_00287 9.2e-161 spoIVFB S Stage IV sporulation protein
MEGKGOFH_00288 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MEGKGOFH_00289 4.5e-55 ysxB J ribosomal protein
MEGKGOFH_00290 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MEGKGOFH_00291 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MEGKGOFH_00292 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEGKGOFH_00293 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MEGKGOFH_00294 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
MEGKGOFH_00295 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
MEGKGOFH_00296 2.2e-229 nifS 2.8.1.7 E Cysteine desulfurase
MEGKGOFH_00297 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MEGKGOFH_00298 2.7e-160 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MEGKGOFH_00299 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MEGKGOFH_00300 1.8e-156 safA M spore coat assembly protein SafA
MEGKGOFH_00301 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MEGKGOFH_00302 3.6e-126 yebC K transcriptional regulatory protein
MEGKGOFH_00303 1.5e-261 alsT E Sodium alanine symporter
MEGKGOFH_00305 5.8e-50 S Family of unknown function (DUF5412)
MEGKGOFH_00307 6.5e-119 yrzF T serine threonine protein kinase
MEGKGOFH_00308 2.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MEGKGOFH_00309 5.3e-253 csbX EGP Major facilitator Superfamily
MEGKGOFH_00310 4.8e-93 bofC S BofC C-terminal domain
MEGKGOFH_00311 5.3e-56 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEGKGOFH_00312 1.7e-28 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEGKGOFH_00313 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEGKGOFH_00314 2.6e-18 yrzS S Protein of unknown function (DUF2905)
MEGKGOFH_00315 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MEGKGOFH_00316 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MEGKGOFH_00317 1.1e-38 yajC U Preprotein translocase subunit YajC
MEGKGOFH_00318 1.3e-73 yrzE S Protein of unknown function (DUF3792)
MEGKGOFH_00319 8.8e-11 yrbG S membrane
MEGKGOFH_00320 1e-78 yrbG S membrane
MEGKGOFH_00321 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEGKGOFH_00322 3.6e-48 yrzD S Post-transcriptional regulator
MEGKGOFH_00323 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MEGKGOFH_00324 2.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MEGKGOFH_00325 3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MEGKGOFH_00326 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MEGKGOFH_00327 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEGKGOFH_00328 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEGKGOFH_00329 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEGKGOFH_00330 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
MEGKGOFH_00332 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MEGKGOFH_00333 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MEGKGOFH_00334 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MEGKGOFH_00335 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MEGKGOFH_00336 1.2e-70 cymR K Transcriptional regulator
MEGKGOFH_00337 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
MEGKGOFH_00338 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEGKGOFH_00339 1.4e-15 S COG0457 FOG TPR repeat
MEGKGOFH_00340 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MEGKGOFH_00341 1.8e-83 yrrD S protein conserved in bacteria
MEGKGOFH_00342 9.8e-31 yrzR
MEGKGOFH_00343 8e-08 S Protein of unknown function (DUF3918)
MEGKGOFH_00344 7.6e-107 glnP P ABC transporter
MEGKGOFH_00345 3.6e-109 gluC P ABC transporter
MEGKGOFH_00346 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
MEGKGOFH_00347 6.4e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MEGKGOFH_00348 8.5e-34 yrrI S AI-2E family transporter
MEGKGOFH_00349 1.6e-119 yrrI S AI-2E family transporter
MEGKGOFH_00350 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEGKGOFH_00351 1.7e-41 yrzL S Belongs to the UPF0297 family
MEGKGOFH_00352 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEGKGOFH_00353 1.2e-45 yrzB S Belongs to the UPF0473 family
MEGKGOFH_00354 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MEGKGOFH_00355 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
MEGKGOFH_00356 3.9e-173 yegQ O Peptidase U32
MEGKGOFH_00357 2.7e-246 yegQ O COG0826 Collagenase and related proteases
MEGKGOFH_00358 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MEGKGOFH_00359 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEGKGOFH_00360 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MEGKGOFH_00361 4.2e-63 yrrS S Protein of unknown function (DUF1510)
MEGKGOFH_00362 1e-25 yrzA S Protein of unknown function (DUF2536)
MEGKGOFH_00363 7.6e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MEGKGOFH_00364 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEGKGOFH_00365 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MEGKGOFH_00366 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MEGKGOFH_00367 4.6e-35 yrhC S YrhC-like protein
MEGKGOFH_00368 2.1e-58 yrhD S Protein of unknown function (DUF1641)
MEGKGOFH_00369 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MEGKGOFH_00370 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
MEGKGOFH_00372 3e-142 focA P Formate nitrite
MEGKGOFH_00374 8.3e-42 yrhH Q methyltransferase
MEGKGOFH_00375 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MEGKGOFH_00376 7.3e-109 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MEGKGOFH_00377 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MEGKGOFH_00378 1.5e-46 yrhK S YrhK-like protein
MEGKGOFH_00379 0.0 yrhL I Acyltransferase family
MEGKGOFH_00380 3.8e-151 rsiV S Protein of unknown function (DUF3298)
MEGKGOFH_00381 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MEGKGOFH_00382 5.9e-149 yrhO K Archaeal transcriptional regulator TrmB
MEGKGOFH_00383 4e-105 yrhP E LysE type translocator
MEGKGOFH_00384 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MEGKGOFH_00385 0.0 levR K PTS system fructose IIA component
MEGKGOFH_00386 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
MEGKGOFH_00387 8.2e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MEGKGOFH_00388 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MEGKGOFH_00389 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MEGKGOFH_00390 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MEGKGOFH_00391 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MEGKGOFH_00392 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
MEGKGOFH_00393 3.5e-28 yphJ 4.1.1.44 S peroxiredoxin activity
MEGKGOFH_00394 4.3e-47 yraB K helix_turn_helix, mercury resistance
MEGKGOFH_00395 1.1e-49 yraD M Spore coat protein
MEGKGOFH_00396 7.5e-26 yraE
MEGKGOFH_00397 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MEGKGOFH_00398 6.4e-63 yraF M Spore coat protein
MEGKGOFH_00399 1.5e-36 yraG
MEGKGOFH_00400 3.8e-66 E Glyoxalase-like domain
MEGKGOFH_00402 2.4e-61 T sh3 domain protein
MEGKGOFH_00403 2.2e-60 T sh3 domain protein
MEGKGOFH_00404 2.3e-153 S Alpha beta hydrolase
MEGKGOFH_00405 3.5e-39 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEGKGOFH_00406 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MEGKGOFH_00407 1.6e-205 yraM S PrpF protein
MEGKGOFH_00408 3.4e-163 yraN K Transcriptional regulator
MEGKGOFH_00409 6.1e-225 yraO C Citrate transporter
MEGKGOFH_00410 2.9e-187 yrpG C Aldo/keto reductase family
MEGKGOFH_00411 7e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MEGKGOFH_00412 1.7e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MEGKGOFH_00414 3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MEGKGOFH_00415 1.2e-169 ssuA M Sulfonate ABC transporter
MEGKGOFH_00416 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MEGKGOFH_00417 5.8e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MEGKGOFH_00419 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEGKGOFH_00420 4.1e-78 ygaO
MEGKGOFH_00421 4.4e-29 K Transcriptional regulator
MEGKGOFH_00423 3.9e-113 yhzB S B3/4 domain
MEGKGOFH_00424 1.1e-222 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MEGKGOFH_00425 1.1e-175 yhbB S Putative amidase domain
MEGKGOFH_00426 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEGKGOFH_00427 1.8e-108 yhbD K Protein of unknown function (DUF4004)
MEGKGOFH_00428 1e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MEGKGOFH_00429 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MEGKGOFH_00430 0.0 prkA T Ser protein kinase
MEGKGOFH_00431 2.5e-225 yhbH S Belongs to the UPF0229 family
MEGKGOFH_00433 2.2e-76 yhbI K DNA-binding transcription factor activity
MEGKGOFH_00434 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MEGKGOFH_00435 3.1e-271 yhcA EGP Major facilitator Superfamily
MEGKGOFH_00436 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MEGKGOFH_00437 2.8e-37 yhcC
MEGKGOFH_00439 1.6e-23
MEGKGOFH_00440 1.9e-59 yhcF K Transcriptional regulator
MEGKGOFH_00441 4e-122 yhcG V ABC transporter, ATP-binding protein
MEGKGOFH_00442 6.5e-165 yhcH V ABC transporter, ATP-binding protein
MEGKGOFH_00443 8.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MEGKGOFH_00444 1e-30 cspB K Cold-shock protein
MEGKGOFH_00445 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
MEGKGOFH_00446 3.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MEGKGOFH_00447 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEGKGOFH_00448 2.9e-41 yhcM
MEGKGOFH_00449 3.5e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MEGKGOFH_00450 7.3e-167 yhcP
MEGKGOFH_00451 1.5e-99 yhcQ M Spore coat protein
MEGKGOFH_00452 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MEGKGOFH_00453 1.4e-90 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MEGKGOFH_00454 1.4e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEGKGOFH_00455 4.6e-67 yhcU S Family of unknown function (DUF5365)
MEGKGOFH_00456 9.9e-68 yhcV S COG0517 FOG CBS domain
MEGKGOFH_00457 6.6e-119 yhcW 5.4.2.6 S hydrolase
MEGKGOFH_00458 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MEGKGOFH_00459 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEGKGOFH_00460 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MEGKGOFH_00461 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MEGKGOFH_00462 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEGKGOFH_00463 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MEGKGOFH_00464 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MEGKGOFH_00465 1.5e-24 yhcY 2.7.13.3 T Histidine kinase
MEGKGOFH_00466 4.6e-171 yhcY 2.7.13.3 T Histidine kinase
MEGKGOFH_00467 1.7e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEGKGOFH_00468 3.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
MEGKGOFH_00469 1.2e-38 yhdB S YhdB-like protein
MEGKGOFH_00470 4.8e-54 yhdC S Protein of unknown function (DUF3889)
MEGKGOFH_00471 4.3e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MEGKGOFH_00472 1e-75 nsrR K Transcriptional regulator
MEGKGOFH_00473 3.6e-237 ygxB M Conserved TM helix
MEGKGOFH_00474 2.1e-276 ycgB S Stage V sporulation protein R
MEGKGOFH_00475 2.5e-178 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MEGKGOFH_00476 2.2e-64 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MEGKGOFH_00477 3.4e-07 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MEGKGOFH_00478 3.2e-107 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MEGKGOFH_00479 3.8e-162 citR K Transcriptional regulator
MEGKGOFH_00480 1.2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
MEGKGOFH_00481 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_00482 3.4e-250 yhdG E amino acid
MEGKGOFH_00483 6.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MEGKGOFH_00484 4.6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEGKGOFH_00485 5.9e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEGKGOFH_00486 8.1e-45 yhdK S Sigma-M inhibitor protein
MEGKGOFH_00487 6.6e-201 yhdL S Sigma factor regulator N-terminal
MEGKGOFH_00488 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MEGKGOFH_00489 2.6e-191 yhdN C Aldo keto reductase
MEGKGOFH_00490 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MEGKGOFH_00491 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MEGKGOFH_00492 4.1e-74 cueR K transcriptional
MEGKGOFH_00493 2.4e-220 yhdR 2.6.1.1 E Aminotransferase
MEGKGOFH_00494 2.5e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MEGKGOFH_00495 1.3e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEGKGOFH_00496 2.1e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEGKGOFH_00497 2e-132 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MEGKGOFH_00499 9.9e-184 yhdY M Mechanosensitive ion channel
MEGKGOFH_00500 5.5e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MEGKGOFH_00501 2.3e-148 yheN G deacetylase
MEGKGOFH_00502 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MEGKGOFH_00503 3.3e-229 nhaC C Na H antiporter
MEGKGOFH_00504 7.6e-84 nhaX T Belongs to the universal stress protein A family
MEGKGOFH_00505 7.8e-28 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MEGKGOFH_00506 1.5e-261 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MEGKGOFH_00507 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MEGKGOFH_00508 3.7e-111 yheG GM NAD(P)H-binding
MEGKGOFH_00509 6.3e-28 sspB S spore protein
MEGKGOFH_00510 1.3e-36 yheE S Family of unknown function (DUF5342)
MEGKGOFH_00511 1.4e-267 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MEGKGOFH_00512 6.2e-215 yheC HJ YheC/D like ATP-grasp
MEGKGOFH_00513 6.3e-202 yheB S Belongs to the UPF0754 family
MEGKGOFH_00514 9.5e-48 yheA S Belongs to the UPF0342 family
MEGKGOFH_00515 1.1e-153 yhaZ L DNA alkylation repair enzyme
MEGKGOFH_00516 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MEGKGOFH_00517 2.3e-292 hemZ H coproporphyrinogen III oxidase
MEGKGOFH_00518 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MEGKGOFH_00519 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MEGKGOFH_00521 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
MEGKGOFH_00522 1.1e-26 S YhzD-like protein
MEGKGOFH_00523 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
MEGKGOFH_00524 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MEGKGOFH_00525 1e-226 yhaO L DNA repair exonuclease
MEGKGOFH_00526 0.0 yhaN L AAA domain
MEGKGOFH_00527 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MEGKGOFH_00528 1.6e-21 yhaL S Sporulation protein YhaL
MEGKGOFH_00529 9.5e-36 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEGKGOFH_00530 2.8e-58 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEGKGOFH_00531 8.7e-90 yhaK S Putative zincin peptidase
MEGKGOFH_00532 1.3e-54 yhaI S Protein of unknown function (DUF1878)
MEGKGOFH_00533 1e-113 hpr K Negative regulator of protease production and sporulation
MEGKGOFH_00534 7e-39 yhaH S YtxH-like protein
MEGKGOFH_00535 3.6e-80 trpP S Tryptophan transporter TrpP
MEGKGOFH_00536 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEGKGOFH_00537 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MEGKGOFH_00538 4.6e-137 ecsA V transporter (ATP-binding protein)
MEGKGOFH_00539 5.4e-215 ecsB U ABC transporter
MEGKGOFH_00540 4.5e-113 ecsC S EcsC protein family
MEGKGOFH_00541 4.1e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MEGKGOFH_00542 5.6e-245 yhfA C membrane
MEGKGOFH_00543 6e-32 1.15.1.2 C Rubrerythrin
MEGKGOFH_00544 4.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MEGKGOFH_00545 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MEGKGOFH_00546 3.5e-188 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MEGKGOFH_00547 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MEGKGOFH_00548 9.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MEGKGOFH_00549 5.4e-101 yhgD K Transcriptional regulator
MEGKGOFH_00550 2.5e-237 yhgE S YhgE Pip N-terminal domain protein
MEGKGOFH_00551 1.5e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEGKGOFH_00552 4.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
MEGKGOFH_00553 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MEGKGOFH_00554 3.7e-72 3.4.13.21 S ASCH
MEGKGOFH_00555 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEGKGOFH_00556 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MEGKGOFH_00557 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
MEGKGOFH_00558 5e-111 yhfK GM NmrA-like family
MEGKGOFH_00559 2.7e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MEGKGOFH_00560 2.1e-64 yhfM
MEGKGOFH_00561 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
MEGKGOFH_00562 6.8e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MEGKGOFH_00563 1.7e-78 VY92_01935 K acetyltransferase
MEGKGOFH_00564 3.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
MEGKGOFH_00565 1.6e-158 yfmC M Periplasmic binding protein
MEGKGOFH_00566 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MEGKGOFH_00567 1.4e-195 vraB 2.3.1.9 I Belongs to the thiolase family
MEGKGOFH_00568 1.8e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MEGKGOFH_00569 1.9e-90 bioY S BioY family
MEGKGOFH_00570 1.7e-182 hemAT NT chemotaxis protein
MEGKGOFH_00571 2.3e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MEGKGOFH_00572 4.5e-52 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_00573 5.1e-96 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_00574 6.3e-28 yhzC S IDEAL
MEGKGOFH_00575 4.2e-109 comK K Competence transcription factor
MEGKGOFH_00576 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
MEGKGOFH_00577 7.8e-42 yhjA S Excalibur calcium-binding domain
MEGKGOFH_00578 7.5e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEGKGOFH_00579 6.9e-27 yhjC S Protein of unknown function (DUF3311)
MEGKGOFH_00580 6.7e-60 yhjD
MEGKGOFH_00581 9.1e-110 yhjE S SNARE associated Golgi protein
MEGKGOFH_00582 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MEGKGOFH_00583 1.3e-282 yhjG CH FAD binding domain
MEGKGOFH_00584 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MEGKGOFH_00585 2.6e-214 glcP G Major Facilitator Superfamily
MEGKGOFH_00586 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MEGKGOFH_00587 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MEGKGOFH_00588 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MEGKGOFH_00589 1.3e-187 yhjM 5.1.1.1 K Transcriptional regulator
MEGKGOFH_00590 4.2e-201 abrB S membrane
MEGKGOFH_00591 1.3e-210 EGP Transmembrane secretion effector
MEGKGOFH_00592 8e-71 S AAA domain
MEGKGOFH_00593 9.3e-24
MEGKGOFH_00594 4.1e-45 K MarR family
MEGKGOFH_00595 2.5e-50 yckD S Protein of unknown function (DUF2680)
MEGKGOFH_00596 5.3e-75 yckC S membrane
MEGKGOFH_00598 4e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MEGKGOFH_00599 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
MEGKGOFH_00600 7e-228 yciC S GTPases (G3E family)
MEGKGOFH_00601 4.2e-101 yciB M ErfK YbiS YcfS YnhG
MEGKGOFH_00602 3.9e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MEGKGOFH_00603 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
MEGKGOFH_00604 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MEGKGOFH_00605 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEGKGOFH_00606 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MEGKGOFH_00607 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
MEGKGOFH_00608 1.3e-281 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MEGKGOFH_00609 2.1e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MEGKGOFH_00610 3.1e-55 I alpha/beta hydrolase fold
MEGKGOFH_00611 3.9e-41 I alpha/beta hydrolase fold
MEGKGOFH_00612 1.7e-138 ycgR S permeases
MEGKGOFH_00613 2.2e-146 ycgQ S membrane
MEGKGOFH_00614 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MEGKGOFH_00615 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEGKGOFH_00616 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MEGKGOFH_00617 8.7e-170 ycgM E Proline dehydrogenase
MEGKGOFH_00618 1.2e-143 ycgL S Predicted nucleotidyltransferase
MEGKGOFH_00619 8e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MEGKGOFH_00620 1.6e-177 oxyR3 K LysR substrate binding domain
MEGKGOFH_00621 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
MEGKGOFH_00622 5.1e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MEGKGOFH_00624 2.3e-107 tmrB S AAA domain
MEGKGOFH_00625 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MEGKGOFH_00626 2.4e-112 ycgI S Domain of unknown function (DUF1989)
MEGKGOFH_00627 1.1e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MEGKGOFH_00628 1.3e-150 yqcI S YqcI/YcgG family
MEGKGOFH_00629 6.8e-113 ycgF E Lysine exporter protein LysE YggA
MEGKGOFH_00630 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
MEGKGOFH_00631 3.9e-263 mdr EGP Major facilitator Superfamily
MEGKGOFH_00632 3.9e-290 lctP C L-lactate permease
MEGKGOFH_00633 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MEGKGOFH_00634 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MEGKGOFH_00635 3.5e-80 ycgB
MEGKGOFH_00636 4.7e-255 ycgA S Membrane
MEGKGOFH_00637 1.4e-217 amhX S amidohydrolase
MEGKGOFH_00638 1.5e-163 opuAC E glycine betaine
MEGKGOFH_00639 8.5e-127 opuAB P glycine betaine
MEGKGOFH_00640 5.1e-229 proV 3.6.3.32 E glycine betaine
MEGKGOFH_00641 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MEGKGOFH_00642 5.7e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
MEGKGOFH_00643 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
MEGKGOFH_00644 2e-192 yceH P Belongs to the TelA family
MEGKGOFH_00645 0.0 yceG S Putative component of 'biosynthetic module'
MEGKGOFH_00646 7e-136 terC P Protein of unknown function (DUF475)
MEGKGOFH_00647 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MEGKGOFH_00648 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MEGKGOFH_00649 1.9e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MEGKGOFH_00650 4.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEGKGOFH_00651 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MEGKGOFH_00652 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MEGKGOFH_00653 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
MEGKGOFH_00654 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MEGKGOFH_00655 6.8e-139 IQ Enoyl-(Acyl carrier protein) reductase
MEGKGOFH_00656 2.3e-172 S response regulator aspartate phosphatase
MEGKGOFH_00657 1.1e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
MEGKGOFH_00658 6.1e-261 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MEGKGOFH_00659 3.4e-269 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MEGKGOFH_00660 6.6e-177 ycdA S Domain of unknown function (DUF5105)
MEGKGOFH_00661 6e-174 yccK C Aldo keto reductase
MEGKGOFH_00662 3.5e-200 natB CP ABC-2 family transporter protein
MEGKGOFH_00663 5e-60 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MEGKGOFH_00664 2.9e-34 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MEGKGOFH_00665 1.2e-126 lytR_2 T LytTr DNA-binding domain
MEGKGOFH_00666 9.5e-159 2.7.13.3 T GHKL domain
MEGKGOFH_00667 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
MEGKGOFH_00668 7.1e-57 S RDD family
MEGKGOFH_00669 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MEGKGOFH_00670 1.3e-199 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MEGKGOFH_00671 6.3e-102 yxaF K Transcriptional regulator
MEGKGOFH_00672 3e-225 lmrB EGP the major facilitator superfamily
MEGKGOFH_00673 2.7e-205 ycbU E Selenocysteine lyase
MEGKGOFH_00674 1.3e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MEGKGOFH_00675 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MEGKGOFH_00676 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MEGKGOFH_00677 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MEGKGOFH_00678 5.3e-71 ycbR T vWA found in TerF C terminus
MEGKGOFH_00679 2.3e-51 ycbR T vWA found in TerF C terminus
MEGKGOFH_00680 1.3e-78 sleB 3.5.1.28 M Cell wall
MEGKGOFH_00681 8.2e-53 ycbP S Protein of unknown function (DUF2512)
MEGKGOFH_00682 2.1e-115 S ABC-2 family transporter protein
MEGKGOFH_00683 4.8e-168 ycbN V ABC transporter, ATP-binding protein
MEGKGOFH_00684 3.8e-168 T PhoQ Sensor
MEGKGOFH_00685 2.9e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_00686 2.8e-112 eamA1 EG spore germination
MEGKGOFH_00687 6.6e-47 eamA1 EG spore germination
MEGKGOFH_00688 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MEGKGOFH_00689 3.1e-175 ycbJ S Macrolide 2'-phosphotransferase
MEGKGOFH_00690 5.9e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
MEGKGOFH_00691 1.9e-124 ycbG K FCD
MEGKGOFH_00692 1.9e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MEGKGOFH_00693 1.7e-254 gudP G COG0477 Permeases of the major facilitator superfamily
MEGKGOFH_00694 1.1e-200 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEGKGOFH_00695 1.6e-54 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEGKGOFH_00696 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MEGKGOFH_00697 2.6e-169 glnL T Regulator
MEGKGOFH_00698 2.1e-228 phoQ 2.7.13.3 T Histidine kinase
MEGKGOFH_00699 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
MEGKGOFH_00700 1.3e-255 agcS E Sodium alanine symporter
MEGKGOFH_00701 3.9e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MEGKGOFH_00702 2.4e-259 mmuP E amino acid
MEGKGOFH_00703 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MEGKGOFH_00705 4.9e-128 K UTRA
MEGKGOFH_00706 8.8e-136 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEGKGOFH_00707 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MEGKGOFH_00708 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEGKGOFH_00709 8.6e-192 yceA S Belongs to the UPF0176 family
MEGKGOFH_00710 2.7e-07 S Erythromycin esterase
MEGKGOFH_00711 4.6e-45 ybfN
MEGKGOFH_00712 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MEGKGOFH_00713 2.7e-85 ybfM S SNARE associated Golgi protein
MEGKGOFH_00714 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEGKGOFH_00715 9.7e-166 S Alpha/beta hydrolase family
MEGKGOFH_00717 1.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MEGKGOFH_00718 4.4e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEGKGOFH_00719 2.3e-145 msmR K AraC-like ligand binding domain
MEGKGOFH_00720 5.7e-161 ybfH EG EamA-like transporter family
MEGKGOFH_00721 0.0 ybfG M Domain of unknown function (DUF1906)
MEGKGOFH_00723 5.5e-223 ybfB G COG0477 Permeases of the major facilitator superfamily
MEGKGOFH_00724 5.7e-169 ybfA 3.4.15.5 K FR47-like protein
MEGKGOFH_00725 1.5e-34 S Protein of unknown function (DUF2651)
MEGKGOFH_00726 7.3e-258 glpT G -transporter
MEGKGOFH_00727 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MEGKGOFH_00728 1e-249 ybeC E amino acid
MEGKGOFH_00729 1.8e-28 ybeC E amino acid
MEGKGOFH_00730 4.9e-41 ybyB
MEGKGOFH_00731 7.8e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MEGKGOFH_00732 2.9e-145 ybxI 3.5.2.6 V beta-lactamase
MEGKGOFH_00733 1.8e-29 ybxH S Family of unknown function (DUF5370)
MEGKGOFH_00734 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
MEGKGOFH_00735 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MEGKGOFH_00736 4e-215 ybdO S Domain of unknown function (DUF4885)
MEGKGOFH_00737 1.7e-151 ybdN
MEGKGOFH_00738 3.9e-139 KLT Protein tyrosine kinase
MEGKGOFH_00739 1.8e-168 T His Kinase A (phospho-acceptor) domain
MEGKGOFH_00740 1.5e-123 T Transcriptional regulatory protein, C terminal
MEGKGOFH_00741 3.8e-179 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MEGKGOFH_00742 1.2e-55
MEGKGOFH_00743 2.9e-202 ybcL EGP Major facilitator Superfamily
MEGKGOFH_00744 5.1e-50 ybzH K Helix-turn-helix domain
MEGKGOFH_00745 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
MEGKGOFH_00746 1.1e-46
MEGKGOFH_00748 2.8e-91 can 4.2.1.1 P carbonic anhydrase
MEGKGOFH_00749 0.0 ybcC S Belongs to the UPF0753 family
MEGKGOFH_00750 1e-271 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MEGKGOFH_00751 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEGKGOFH_00752 1.5e-120 adaA 3.2.2.21 K Transcriptional regulator
MEGKGOFH_00753 1.4e-175 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MEGKGOFH_00754 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEGKGOFH_00755 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEGKGOFH_00756 5.7e-213 yetA
MEGKGOFH_00757 1.2e-282 lplA G Bacterial extracellular solute-binding protein
MEGKGOFH_00758 5.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MEGKGOFH_00759 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
MEGKGOFH_00760 1.2e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MEGKGOFH_00761 8.8e-122 yetF S membrane
MEGKGOFH_00762 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MEGKGOFH_00763 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEGKGOFH_00764 2.2e-34
MEGKGOFH_00765 7.1e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MEGKGOFH_00766 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
MEGKGOFH_00767 9.1e-105 yetJ S Belongs to the BI1 family
MEGKGOFH_00768 5.4e-159 yetK EG EamA-like transporter family
MEGKGOFH_00769 6.8e-53 yetL K helix_turn_helix multiple antibiotic resistance protein
MEGKGOFH_00770 8.6e-14 yetL K helix_turn_helix multiple antibiotic resistance protein
MEGKGOFH_00771 7.8e-213 yetM CH FAD binding domain
MEGKGOFH_00772 1e-198 yetN S Protein of unknown function (DUF3900)
MEGKGOFH_00773 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MEGKGOFH_00774 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MEGKGOFH_00775 3e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
MEGKGOFH_00776 7.1e-172 yfnG 4.2.1.45 M dehydratase
MEGKGOFH_00777 1.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
MEGKGOFH_00778 4.2e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MEGKGOFH_00779 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
MEGKGOFH_00780 1.7e-205 fsr P COG0477 Permeases of the major facilitator superfamily
MEGKGOFH_00781 1.1e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MEGKGOFH_00782 1.4e-240 yfnA E amino acid
MEGKGOFH_00783 1e-12 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEGKGOFH_00784 1.5e-258 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEGKGOFH_00785 1.1e-113 yfmS NT chemotaxis protein
MEGKGOFH_00786 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MEGKGOFH_00787 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
MEGKGOFH_00788 1.4e-69 yfmP K transcriptional
MEGKGOFH_00789 1.5e-209 yfmO EGP Major facilitator Superfamily
MEGKGOFH_00790 2.1e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MEGKGOFH_00791 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MEGKGOFH_00792 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
MEGKGOFH_00793 3.2e-189 yfmJ S N-terminal domain of oxidoreductase
MEGKGOFH_00794 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MEGKGOFH_00795 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEGKGOFH_00796 5.3e-168 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEGKGOFH_00797 1.4e-46 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MEGKGOFH_00798 3e-70 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MEGKGOFH_00799 5e-24 S Protein of unknown function (DUF3212)
MEGKGOFH_00800 7.6e-58 yflT S Heat induced stress protein YflT
MEGKGOFH_00801 2.5e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MEGKGOFH_00802 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
MEGKGOFH_00803 4.8e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MEGKGOFH_00804 5.8e-118 citT T response regulator
MEGKGOFH_00805 2e-177 yflP S Tripartite tricarboxylate transporter family receptor
MEGKGOFH_00806 8.5e-227 citM C Citrate transporter
MEGKGOFH_00807 1.8e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MEGKGOFH_00808 6.2e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MEGKGOFH_00809 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MEGKGOFH_00810 8.4e-122 yflK S protein conserved in bacteria
MEGKGOFH_00811 4e-18 yflJ S Protein of unknown function (DUF2639)
MEGKGOFH_00812 4.1e-19 yflI
MEGKGOFH_00813 5.3e-50 yflH S Protein of unknown function (DUF3243)
MEGKGOFH_00814 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
MEGKGOFH_00815 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MEGKGOFH_00816 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MEGKGOFH_00817 6e-67 yhdN S Domain of unknown function (DUF1992)
MEGKGOFH_00818 2.2e-252 agcS_1 E Sodium alanine symporter
MEGKGOFH_00819 9.9e-26 yfkQ EG Spore germination protein
MEGKGOFH_00820 2.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MEGKGOFH_00821 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MEGKGOFH_00822 1.8e-133 treR K transcriptional
MEGKGOFH_00823 1.1e-124 yfkO C nitroreductase
MEGKGOFH_00824 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MEGKGOFH_00825 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
MEGKGOFH_00826 1.7e-205 ydiM EGP Major facilitator Superfamily
MEGKGOFH_00827 2.1e-29 yfkK S Belongs to the UPF0435 family
MEGKGOFH_00828 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MEGKGOFH_00829 2.4e-50 yfkI S gas vesicle protein
MEGKGOFH_00830 2.2e-129 yihY S Belongs to the UPF0761 family
MEGKGOFH_00832 2e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MEGKGOFH_00833 1.8e-182 cax P COG0387 Ca2 H antiporter
MEGKGOFH_00834 1.2e-146 yfkD S YfkD-like protein
MEGKGOFH_00835 1.7e-148 yfkC M Mechanosensitive ion channel
MEGKGOFH_00836 1.7e-220 yfkA S YfkB-like domain
MEGKGOFH_00837 1.1e-26 yfjT
MEGKGOFH_00838 6.2e-148 pdaA G deacetylase
MEGKGOFH_00839 3.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MEGKGOFH_00840 1.7e-184 corA P Mediates influx of magnesium ions
MEGKGOFH_00841 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MEGKGOFH_00842 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEGKGOFH_00843 3.9e-44 S YfzA-like protein
MEGKGOFH_00844 1.8e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEGKGOFH_00845 6.4e-81 yfjM S Psort location Cytoplasmic, score
MEGKGOFH_00846 1e-29 yfjL
MEGKGOFH_00847 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MEGKGOFH_00848 3.6e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MEGKGOFH_00849 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEGKGOFH_00850 1.4e-105 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MEGKGOFH_00851 1.7e-137 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MEGKGOFH_00852 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MEGKGOFH_00853 9.8e-25 sspH S Belongs to the SspH family
MEGKGOFH_00854 4e-56 yfjF S UPF0060 membrane protein
MEGKGOFH_00855 1.1e-79 S Family of unknown function (DUF5381)
MEGKGOFH_00856 1.8e-101 yfjD S Family of unknown function (DUF5381)
MEGKGOFH_00857 4.5e-143 yfjC
MEGKGOFH_00858 2.1e-187 yfjB
MEGKGOFH_00859 7.4e-44 yfjA S Belongs to the WXG100 family
MEGKGOFH_00860 1.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MEGKGOFH_00861 3.3e-138 glvR K Helix-turn-helix domain, rpiR family
MEGKGOFH_00862 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MEGKGOFH_00863 2.6e-308 yfiB3 V ABC transporter
MEGKGOFH_00864 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MEGKGOFH_00865 6.4e-64 mhqP S DoxX
MEGKGOFH_00866 5.7e-163 yfiE 1.13.11.2 S glyoxalase
MEGKGOFH_00868 3.1e-212 yxjM T Histidine kinase
MEGKGOFH_00869 4.6e-112 KT LuxR family transcriptional regulator
MEGKGOFH_00870 2.2e-168 V ABC transporter, ATP-binding protein
MEGKGOFH_00871 1.8e-207 V ABC-2 family transporter protein
MEGKGOFH_00872 5.8e-203 V COG0842 ABC-type multidrug transport system, permease component
MEGKGOFH_00873 8.3e-99 padR K transcriptional
MEGKGOFH_00874 2.7e-46 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MEGKGOFH_00875 1.5e-27 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MEGKGOFH_00876 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MEGKGOFH_00877 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
MEGKGOFH_00878 2.6e-283 yfiU EGP Major facilitator Superfamily
MEGKGOFH_00879 1.1e-78 yfiV K transcriptional
MEGKGOFH_00880 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEGKGOFH_00881 6.2e-182 yfiY P ABC transporter substrate-binding protein
MEGKGOFH_00882 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEGKGOFH_00883 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEGKGOFH_00884 1.3e-165 yfhB 5.3.3.17 S PhzF family
MEGKGOFH_00885 1.5e-106 yfhC C nitroreductase
MEGKGOFH_00886 2.1e-25 yfhD S YfhD-like protein
MEGKGOFH_00888 1.4e-172 yfhF S nucleoside-diphosphate sugar epimerase
MEGKGOFH_00889 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MEGKGOFH_00890 9.7e-52 yfhH S Protein of unknown function (DUF1811)
MEGKGOFH_00892 1.1e-209 yfhI EGP Major facilitator Superfamily
MEGKGOFH_00893 6.2e-20 sspK S reproduction
MEGKGOFH_00894 4.7e-27 yfhJ S WVELL protein
MEGKGOFH_00895 2.4e-87 batE T Bacterial SH3 domain homologues
MEGKGOFH_00896 3.5e-51 yfhL S SdpI/YhfL protein family
MEGKGOFH_00897 6.7e-172 yfhM S Alpha beta hydrolase
MEGKGOFH_00898 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MEGKGOFH_00899 0.0 yfhO S Bacterial membrane protein YfhO
MEGKGOFH_00900 5.5e-186 yfhP S membrane-bound metal-dependent
MEGKGOFH_00901 7.8e-212 mutY L A G-specific
MEGKGOFH_00902 6.9e-36 yfhS
MEGKGOFH_00903 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_00904 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
MEGKGOFH_00905 1.5e-37 ygaB S YgaB-like protein
MEGKGOFH_00906 1.3e-104 ygaC J Belongs to the UPF0374 family
MEGKGOFH_00907 1.8e-301 ygaD V ABC transporter
MEGKGOFH_00908 8.7e-180 ygaE S Membrane
MEGKGOFH_00909 5.2e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MEGKGOFH_00910 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
MEGKGOFH_00911 4e-80 perR P Belongs to the Fur family
MEGKGOFH_00912 9.5e-56 ygzB S UPF0295 protein
MEGKGOFH_00913 6.7e-167 ygxA S Nucleotidyltransferase-like
MEGKGOFH_00914 3.4e-39 S COG NOG14552 non supervised orthologous group
MEGKGOFH_00915 6.6e-69 ylxW S protein conserved in bacteria
MEGKGOFH_00916 4.2e-105 ylxX S protein conserved in bacteria
MEGKGOFH_00917 6.2e-58 sbp S small basic protein
MEGKGOFH_00918 6e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEGKGOFH_00919 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEGKGOFH_00920 0.0 bpr O COG1404 Subtilisin-like serine proteases
MEGKGOFH_00921 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MEGKGOFH_00922 5e-24 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEGKGOFH_00923 8.1e-88 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEGKGOFH_00924 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEGKGOFH_00925 3.2e-127 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MEGKGOFH_00926 2.3e-253 argE 3.5.1.16 E Acetylornithine deacetylase
MEGKGOFH_00927 9e-37 ylmC S sporulation protein
MEGKGOFH_00928 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MEGKGOFH_00929 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MEGKGOFH_00930 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEGKGOFH_00931 1.3e-39 yggT S membrane
MEGKGOFH_00932 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MEGKGOFH_00933 2.6e-67 divIVA D Cell division initiation protein
MEGKGOFH_00934 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEGKGOFH_00935 8.5e-63 dksA T COG1734 DnaK suppressor protein
MEGKGOFH_00936 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEGKGOFH_00937 4.2e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEGKGOFH_00938 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEGKGOFH_00939 2.6e-231 pyrP F Xanthine uracil
MEGKGOFH_00940 8.5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MEGKGOFH_00941 4.6e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEGKGOFH_00942 1.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MEGKGOFH_00943 0.0 carB 6.3.5.5 F Belongs to the CarB family
MEGKGOFH_00944 2.3e-27 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MEGKGOFH_00945 2.1e-108 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MEGKGOFH_00946 4.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEGKGOFH_00947 3e-55 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEGKGOFH_00948 2.1e-52 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEGKGOFH_00949 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEGKGOFH_00951 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MEGKGOFH_00952 1.4e-179 cysP P phosphate transporter
MEGKGOFH_00953 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MEGKGOFH_00954 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MEGKGOFH_00955 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MEGKGOFH_00956 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MEGKGOFH_00957 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MEGKGOFH_00958 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MEGKGOFH_00959 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MEGKGOFH_00960 6.9e-156 yloC S stress-induced protein
MEGKGOFH_00961 1.5e-40 ylzA S Belongs to the UPF0296 family
MEGKGOFH_00962 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MEGKGOFH_00963 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEGKGOFH_00964 1.6e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEGKGOFH_00965 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEGKGOFH_00966 7.3e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEGKGOFH_00967 1.3e-137 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEGKGOFH_00968 1.2e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MEGKGOFH_00969 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MEGKGOFH_00970 1.8e-139 stp 3.1.3.16 T phosphatase
MEGKGOFH_00971 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MEGKGOFH_00972 2.1e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEGKGOFH_00973 6e-91 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MEGKGOFH_00974 4.4e-19 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MEGKGOFH_00975 4.3e-29 thiN 2.7.6.2 H thiamine pyrophosphokinase
MEGKGOFH_00976 1.4e-77 thiN 2.7.6.2 H thiamine pyrophosphokinase
MEGKGOFH_00977 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MEGKGOFH_00978 5.5e-59 asp S protein conserved in bacteria
MEGKGOFH_00979 4.8e-299 yloV S kinase related to dihydroxyacetone kinase
MEGKGOFH_00980 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MEGKGOFH_00981 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
MEGKGOFH_00982 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEGKGOFH_00983 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MEGKGOFH_00984 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEGKGOFH_00985 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MEGKGOFH_00986 2.9e-15 IQ reductase
MEGKGOFH_00987 8.8e-90 IQ reductase
MEGKGOFH_00988 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEGKGOFH_00989 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEGKGOFH_00990 0.0 smc D Required for chromosome condensation and partitioning
MEGKGOFH_00991 2.7e-98 smc D Required for chromosome condensation and partitioning
MEGKGOFH_00992 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEGKGOFH_00993 2.9e-87
MEGKGOFH_00994 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MEGKGOFH_00995 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEGKGOFH_00996 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MEGKGOFH_00997 4.5e-36 ylqC S Belongs to the UPF0109 family
MEGKGOFH_00998 1.4e-60 ylqD S YlqD protein
MEGKGOFH_00999 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEGKGOFH_01000 2.1e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MEGKGOFH_01001 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEGKGOFH_01002 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MEGKGOFH_01003 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEGKGOFH_01004 8.5e-291 ylqG
MEGKGOFH_01005 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MEGKGOFH_01006 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MEGKGOFH_01007 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MEGKGOFH_01008 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MEGKGOFH_01009 3.8e-42 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEGKGOFH_01010 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEGKGOFH_01011 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MEGKGOFH_01012 2.5e-169 xerC L tyrosine recombinase XerC
MEGKGOFH_01013 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MEGKGOFH_01014 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MEGKGOFH_01015 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MEGKGOFH_01016 5.6e-14 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MEGKGOFH_01017 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
MEGKGOFH_01018 1.9e-31 fliE N Flagellar hook-basal body
MEGKGOFH_01019 2.6e-254 fliF N The M ring may be actively involved in energy transduction
MEGKGOFH_01020 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MEGKGOFH_01021 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MEGKGOFH_01022 9.4e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MEGKGOFH_01023 1.8e-08 fliJ N Flagellar biosynthesis chaperone
MEGKGOFH_01024 2.6e-36 fliJ N Flagellar biosynthesis chaperone
MEGKGOFH_01025 7.7e-37 ylxF S MgtE intracellular N domain
MEGKGOFH_01026 2e-216 fliK N Flagellar hook-length control protein
MEGKGOFH_01027 1.7e-72 flgD N Flagellar basal body rod modification protein
MEGKGOFH_01028 8.2e-140 flgG N Flagellar basal body rod
MEGKGOFH_01029 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MEGKGOFH_01030 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MEGKGOFH_01031 7.7e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MEGKGOFH_01032 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MEGKGOFH_01033 1.6e-96 fliZ N Flagellar biosynthesis protein, FliO
MEGKGOFH_01034 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MEGKGOFH_01035 2.2e-36 fliQ N Role in flagellar biosynthesis
MEGKGOFH_01036 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MEGKGOFH_01037 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MEGKGOFH_01038 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MEGKGOFH_01039 1.2e-194 flhF N Flagellar biosynthesis regulator FlhF
MEGKGOFH_01040 7.5e-158 flhG D Belongs to the ParA family
MEGKGOFH_01041 2.9e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MEGKGOFH_01042 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MEGKGOFH_01043 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MEGKGOFH_01044 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MEGKGOFH_01045 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MEGKGOFH_01046 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEGKGOFH_01047 1.3e-77 ylxL
MEGKGOFH_01048 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MEGKGOFH_01049 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEGKGOFH_01050 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MEGKGOFH_01051 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEGKGOFH_01052 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEGKGOFH_01053 9.9e-11 cdsA 2.7.7.41 S Belongs to the CDS family
MEGKGOFH_01054 1.3e-117 cdsA 2.7.7.41 S Belongs to the CDS family
MEGKGOFH_01055 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MEGKGOFH_01056 7.7e-233 rasP M zinc metalloprotease
MEGKGOFH_01057 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEGKGOFH_01058 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEGKGOFH_01059 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
MEGKGOFH_01060 1.1e-203 nusA K Participates in both transcription termination and antitermination
MEGKGOFH_01061 2.3e-26 ylxR K nucleic-acid-binding protein implicated in transcription termination
MEGKGOFH_01062 3.1e-47 ylxQ J ribosomal protein
MEGKGOFH_01063 7.8e-19 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEGKGOFH_01064 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MEGKGOFH_01065 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MEGKGOFH_01067 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MEGKGOFH_01068 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MEGKGOFH_01069 3e-174 spoIID D Stage II sporulation protein D
MEGKGOFH_01070 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEGKGOFH_01071 2.9e-131 ywmB S TATA-box binding
MEGKGOFH_01072 2.1e-32 ywzB S membrane
MEGKGOFH_01073 4.8e-87 ywmA
MEGKGOFH_01074 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MEGKGOFH_01075 9.9e-149 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEGKGOFH_01076 3.5e-106 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEGKGOFH_01077 2.5e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEGKGOFH_01078 3.4e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEGKGOFH_01079 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEGKGOFH_01080 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEGKGOFH_01081 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEGKGOFH_01082 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
MEGKGOFH_01083 1.6e-61 atpI S ATP synthase
MEGKGOFH_01084 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEGKGOFH_01085 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEGKGOFH_01086 2.7e-94 ywlG S Belongs to the UPF0340 family
MEGKGOFH_01087 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MEGKGOFH_01088 1.9e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MEGKGOFH_01089 1.7e-91 mntP P Probably functions as a manganese efflux pump
MEGKGOFH_01090 5.3e-164 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEGKGOFH_01091 1.8e-23 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEGKGOFH_01092 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MEGKGOFH_01093 6.1e-112 spoIIR S stage II sporulation protein R
MEGKGOFH_01094 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
MEGKGOFH_01096 5e-151 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEGKGOFH_01097 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEGKGOFH_01098 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEGKGOFH_01099 1.2e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MEGKGOFH_01100 8.6e-160 ywkB S Membrane transport protein
MEGKGOFH_01101 0.0 sfcA 1.1.1.38 C malic enzyme
MEGKGOFH_01102 5.4e-104 tdk 2.7.1.21 F thymidine kinase
MEGKGOFH_01103 1.1e-32 rpmE J Binds the 23S rRNA
MEGKGOFH_01104 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MEGKGOFH_01105 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MEGKGOFH_01106 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEGKGOFH_01107 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MEGKGOFH_01108 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MEGKGOFH_01109 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MEGKGOFH_01110 6e-91 ywjG S Domain of unknown function (DUF2529)
MEGKGOFH_01111 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEGKGOFH_01112 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MEGKGOFH_01113 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MEGKGOFH_01114 0.0 fadF C COG0247 Fe-S oxidoreductase
MEGKGOFH_01115 7.2e-63 fadF C COG0247 Fe-S oxidoreductase
MEGKGOFH_01116 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MEGKGOFH_01117 2.1e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MEGKGOFH_01118 2.7e-42 ywjC
MEGKGOFH_01119 1.7e-77 ywjB H RibD C-terminal domain
MEGKGOFH_01120 0.0 ywjA V ABC transporter
MEGKGOFH_01121 4.6e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEGKGOFH_01122 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
MEGKGOFH_01123 1.1e-93 narJ 1.7.5.1 C nitrate reductase
MEGKGOFH_01124 5.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
MEGKGOFH_01125 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEGKGOFH_01126 7e-86 arfM T cyclic nucleotide binding
MEGKGOFH_01127 8.2e-139 ywiC S YwiC-like protein
MEGKGOFH_01128 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
MEGKGOFH_01129 1.3e-213 narK P COG2223 Nitrate nitrite transporter
MEGKGOFH_01130 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MEGKGOFH_01131 4.7e-73 ywiB S protein conserved in bacteria
MEGKGOFH_01132 1e-07 S Bacteriocin subtilosin A
MEGKGOFH_01133 4.9e-270 C Fe-S oxidoreductases
MEGKGOFH_01135 3.3e-132 cbiO V ABC transporter
MEGKGOFH_01136 9.4e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MEGKGOFH_01137 8e-216 2.7.1.26, 2.7.7.2 L Peptidase, M16
MEGKGOFH_01138 2.9e-248 L Peptidase, M16
MEGKGOFH_01140 2.8e-244 ywhL CO amine dehydrogenase activity
MEGKGOFH_01141 5.2e-203 ywhK CO amine dehydrogenase activity
MEGKGOFH_01142 2.6e-78 S aspartate phosphatase
MEGKGOFH_01145 1.7e-20
MEGKGOFH_01148 1.9e-44 V ATPases associated with a variety of cellular activities
MEGKGOFH_01150 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
MEGKGOFH_01151 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MEGKGOFH_01152 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MEGKGOFH_01153 2.9e-93 ywhD S YwhD family
MEGKGOFH_01154 5.1e-119 ywhC S Peptidase family M50
MEGKGOFH_01155 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MEGKGOFH_01156 3.3e-71 ywhA K Transcriptional regulator
MEGKGOFH_01157 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEGKGOFH_01159 8.8e-238 mmr U Major Facilitator Superfamily
MEGKGOFH_01160 2.4e-78 yffB K Transcriptional regulator
MEGKGOFH_01161 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
MEGKGOFH_01162 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
MEGKGOFH_01163 3.1e-36 ywzC S Belongs to the UPF0741 family
MEGKGOFH_01164 1e-110 rsfA_1
MEGKGOFH_01165 5.7e-158 ywfM EG EamA-like transporter family
MEGKGOFH_01166 1.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MEGKGOFH_01167 9.2e-164 cysL K Transcriptional regulator
MEGKGOFH_01168 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MEGKGOFH_01169 1.1e-146 ywfI C May function as heme-dependent peroxidase
MEGKGOFH_01170 4.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
MEGKGOFH_01171 1.1e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
MEGKGOFH_01172 1.6e-208 bacE EGP Major facilitator Superfamily
MEGKGOFH_01173 2.3e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MEGKGOFH_01174 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_01175 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MEGKGOFH_01176 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MEGKGOFH_01177 4.6e-206 ywfA EGP Major facilitator Superfamily
MEGKGOFH_01178 1.5e-261 lysP E amino acid
MEGKGOFH_01179 3.2e-247 rocB E arginine degradation protein
MEGKGOFH_01180 4e-34 rocB E arginine degradation protein
MEGKGOFH_01181 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MEGKGOFH_01182 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MEGKGOFH_01183 1.2e-77
MEGKGOFH_01184 1.3e-86 spsL 5.1.3.13 M Spore Coat
MEGKGOFH_01185 2.9e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MEGKGOFH_01186 1.5e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEGKGOFH_01187 4.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MEGKGOFH_01188 1.2e-188 spsG M Spore Coat
MEGKGOFH_01189 9.7e-132 spsF M Spore Coat
MEGKGOFH_01190 3.5e-213 spsE 2.5.1.56 M acid synthase
MEGKGOFH_01191 2.2e-162 spsD 2.3.1.210 K Spore Coat
MEGKGOFH_01192 1.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
MEGKGOFH_01193 8e-268 spsB M Capsule polysaccharide biosynthesis protein
MEGKGOFH_01194 1.8e-144 spsA M Spore Coat
MEGKGOFH_01195 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MEGKGOFH_01196 4.3e-59 ywdK S small membrane protein
MEGKGOFH_01197 5.4e-237 ywdJ F Xanthine uracil
MEGKGOFH_01198 5e-48 ywdI S Family of unknown function (DUF5327)
MEGKGOFH_01199 2.1e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MEGKGOFH_01200 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEGKGOFH_01201 1.4e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
MEGKGOFH_01203 4e-113 ywdD
MEGKGOFH_01204 1.3e-57 pex K Transcriptional regulator PadR-like family
MEGKGOFH_01205 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MEGKGOFH_01206 2e-28 ywdA
MEGKGOFH_01207 3.2e-291 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MEGKGOFH_01208 2.9e-249 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MEGKGOFH_01209 7.4e-138 focA P Formate/nitrite transporter
MEGKGOFH_01210 1.2e-149 sacT K transcriptional antiterminator
MEGKGOFH_01212 1.6e-106 yvgT S membrane
MEGKGOFH_01213 6.5e-72 bdbC O Required for disulfide bond formation in some proteins
MEGKGOFH_01214 1.6e-104 bdbD O Thioredoxin
MEGKGOFH_01215 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MEGKGOFH_01216 0.0 copA 3.6.3.54 P P-type ATPase
MEGKGOFH_01217 3.7e-67 copA 3.6.3.54 P P-type ATPase
MEGKGOFH_01218 5.9e-29 copZ P Copper resistance protein CopZ
MEGKGOFH_01219 2.2e-48 csoR S transcriptional
MEGKGOFH_01220 1.1e-197 yvaA 1.1.1.371 S Oxidoreductase
MEGKGOFH_01221 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MEGKGOFH_01222 0.0 yvaC S Fusaric acid resistance protein-like
MEGKGOFH_01223 5.7e-73 yvaD S Family of unknown function (DUF5360)
MEGKGOFH_01224 2.8e-55 yvaE P Small Multidrug Resistance protein
MEGKGOFH_01225 4.6e-100 K Bacterial regulatory proteins, tetR family
MEGKGOFH_01226 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGKGOFH_01228 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MEGKGOFH_01229 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEGKGOFH_01230 5.6e-143 est 3.1.1.1 S Carboxylesterase
MEGKGOFH_01231 2.4e-23 secG U Preprotein translocase subunit SecG
MEGKGOFH_01232 3.4e-151 yvaM S Serine aminopeptidase, S33
MEGKGOFH_01233 7.5e-36 yvzC K Transcriptional
MEGKGOFH_01234 4e-69 K transcriptional
MEGKGOFH_01235 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
MEGKGOFH_01236 2.2e-54 yodB K transcriptional
MEGKGOFH_01237 9.1e-221 NT chemotaxis protein
MEGKGOFH_01238 8.7e-106 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MEGKGOFH_01239 6.7e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MEGKGOFH_01240 7.3e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MEGKGOFH_01241 4.4e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MEGKGOFH_01242 3.3e-60 yvbF K Belongs to the GbsR family
MEGKGOFH_01243 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MEGKGOFH_01244 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MEGKGOFH_01245 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MEGKGOFH_01246 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MEGKGOFH_01247 1.4e-98 yvbF K Belongs to the GbsR family
MEGKGOFH_01248 1.9e-102 yvbG U UPF0056 membrane protein
MEGKGOFH_01249 1.9e-112 yvbH S YvbH-like oligomerisation region
MEGKGOFH_01250 2.3e-122 exoY M Membrane
MEGKGOFH_01251 0.0 tcaA S response to antibiotic
MEGKGOFH_01252 1.3e-81 yvbK 3.1.3.25 K acetyltransferase
MEGKGOFH_01253 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEGKGOFH_01254 3.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MEGKGOFH_01255 9.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEGKGOFH_01256 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MEGKGOFH_01257 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEGKGOFH_01258 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MEGKGOFH_01259 1.6e-252 araE EGP Major facilitator Superfamily
MEGKGOFH_01260 3.5e-202 araR K transcriptional
MEGKGOFH_01261 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEGKGOFH_01262 6.7e-159 yvbU K Transcriptional regulator
MEGKGOFH_01263 1.3e-146 yvbV EG EamA-like transporter family
MEGKGOFH_01264 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MEGKGOFH_01265 9.5e-197 yvbX S Glycosyl hydrolase
MEGKGOFH_01266 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MEGKGOFH_01267 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MEGKGOFH_01268 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MEGKGOFH_01269 3.8e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEGKGOFH_01270 2.1e-197 desK 2.7.13.3 T Histidine kinase
MEGKGOFH_01271 1.1e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
MEGKGOFH_01272 1.9e-161 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MEGKGOFH_01273 9.8e-157 rsbQ S Alpha/beta hydrolase family
MEGKGOFH_01274 5.9e-198 rsbU 3.1.3.3 T response regulator
MEGKGOFH_01275 1e-248 galA 3.2.1.89 G arabinogalactan
MEGKGOFH_01276 0.0 lacA 3.2.1.23 G beta-galactosidase
MEGKGOFH_01277 7.2e-150 ganQ P transport
MEGKGOFH_01278 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
MEGKGOFH_01279 2.6e-225 cycB G COG2182 Maltose-binding periplasmic proteins domains
MEGKGOFH_01280 1.2e-183 lacR K Transcriptional regulator
MEGKGOFH_01281 1.5e-62 yvfI K COG2186 Transcriptional regulators
MEGKGOFH_01282 4.1e-39 yvfI K COG2186 Transcriptional regulators
MEGKGOFH_01283 9.1e-306 yvfH C L-lactate permease
MEGKGOFH_01284 3.6e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MEGKGOFH_01285 1e-31 yvfG S YvfG protein
MEGKGOFH_01286 7.1e-186 yvfF GM Exopolysaccharide biosynthesis protein
MEGKGOFH_01287 2e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MEGKGOFH_01288 2e-51 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MEGKGOFH_01289 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MEGKGOFH_01290 1.3e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEGKGOFH_01291 5.2e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MEGKGOFH_01292 4.4e-205 epsI GM pyruvyl transferase
MEGKGOFH_01293 2e-194 epsH GT2 S Glycosyltransferase like family 2
MEGKGOFH_01294 1.1e-206 epsG S EpsG family
MEGKGOFH_01295 3.3e-214 epsF GT4 M Glycosyl transferases group 1
MEGKGOFH_01296 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MEGKGOFH_01297 2.9e-223 epsD GT4 M Glycosyl transferase 4-like
MEGKGOFH_01298 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MEGKGOFH_01299 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MEGKGOFH_01300 4e-122 ywqC M biosynthesis protein
MEGKGOFH_01301 6.3e-76 slr K transcriptional
MEGKGOFH_01302 8.1e-41 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MEGKGOFH_01303 1.7e-218 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MEGKGOFH_01305 1.7e-92 padC Q Phenolic acid decarboxylase
MEGKGOFH_01306 5.8e-74 MA20_18690 S Protein of unknown function (DUF3237)
MEGKGOFH_01307 2.4e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MEGKGOFH_01308 3.8e-262 pbpE V Beta-lactamase
MEGKGOFH_01309 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
MEGKGOFH_01310 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MEGKGOFH_01311 2.3e-295 yveA E amino acid
MEGKGOFH_01312 2.6e-106 yvdT K Transcriptional regulator
MEGKGOFH_01313 6.7e-51 ykkC P Small Multidrug Resistance protein
MEGKGOFH_01314 4.1e-50 sugE P Small Multidrug Resistance protein
MEGKGOFH_01315 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
MEGKGOFH_01316 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
MEGKGOFH_01317 1.5e-183 S Patatin-like phospholipase
MEGKGOFH_01319 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEGKGOFH_01320 4.2e-113 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MEGKGOFH_01321 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MEGKGOFH_01322 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MEGKGOFH_01323 1e-151 malA S Protein of unknown function (DUF1189)
MEGKGOFH_01324 9.5e-147 malD P transport
MEGKGOFH_01325 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
MEGKGOFH_01326 1.8e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MEGKGOFH_01327 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MEGKGOFH_01328 2.9e-73 yvdE K Transcriptional regulator
MEGKGOFH_01329 2.1e-91 yvdE K Transcriptional regulator
MEGKGOFH_01330 1.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
MEGKGOFH_01331 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
MEGKGOFH_01332 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MEGKGOFH_01333 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MEGKGOFH_01334 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEGKGOFH_01335 0.0 yxdM V ABC transporter (permease)
MEGKGOFH_01336 5.6e-141 yvcR V ABC transporter, ATP-binding protein
MEGKGOFH_01337 2.9e-196 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MEGKGOFH_01338 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_01339 3.3e-32
MEGKGOFH_01340 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MEGKGOFH_01341 1.6e-36 crh G Phosphocarrier protein Chr
MEGKGOFH_01342 1.4e-170 whiA K May be required for sporulation
MEGKGOFH_01343 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MEGKGOFH_01344 5.7e-166 rapZ S Displays ATPase and GTPase activities
MEGKGOFH_01345 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MEGKGOFH_01346 6.1e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEGKGOFH_01347 1.8e-69 usp CBM50 M protein conserved in bacteria
MEGKGOFH_01348 3.4e-39 S COG NOG14552 non supervised orthologous group
MEGKGOFH_01351 7.9e-157 ydhU P Catalase
MEGKGOFH_01352 1.6e-196 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MEGKGOFH_01353 3.4e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
MEGKGOFH_01354 1.2e-168 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MEGKGOFH_01355 1.1e-132 ydhQ K UTRA
MEGKGOFH_01356 9.9e-282 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEGKGOFH_01357 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEGKGOFH_01358 8.7e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MEGKGOFH_01359 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MEGKGOFH_01360 4.6e-200 pbuE EGP Major facilitator Superfamily
MEGKGOFH_01361 2.5e-98 ydhK M Protein of unknown function (DUF1541)
MEGKGOFH_01362 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MEGKGOFH_01363 4.1e-86 K Acetyltransferase (GNAT) domain
MEGKGOFH_01365 4.6e-69 frataxin S Domain of unknown function (DU1801)
MEGKGOFH_01366 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MEGKGOFH_01367 1.9e-127
MEGKGOFH_01368 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MEGKGOFH_01369 3.3e-244 ydhD M Glycosyl hydrolase
MEGKGOFH_01370 6.5e-122 ydhC K FCD
MEGKGOFH_01371 3.5e-121 ydhB S membrane transporter protein
MEGKGOFH_01372 7.4e-209 tcaB EGP Major facilitator Superfamily
MEGKGOFH_01373 2.4e-69 ydgJ K Winged helix DNA-binding domain
MEGKGOFH_01374 2.3e-113 drgA C nitroreductase
MEGKGOFH_01375 0.0 ydgH S drug exporters of the RND superfamily
MEGKGOFH_01376 1.8e-79 K helix_turn_helix multiple antibiotic resistance protein
MEGKGOFH_01377 4.6e-91 dinB S DinB family
MEGKGOFH_01378 1.2e-137 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MEGKGOFH_01379 1.2e-71 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MEGKGOFH_01380 2.3e-301 expZ S ABC transporter
MEGKGOFH_01381 1.3e-103 G Xylose isomerase-like TIM barrel
MEGKGOFH_01382 2.2e-190 csbC EGP Major facilitator Superfamily
MEGKGOFH_01383 2e-119 purR K helix_turn _helix lactose operon repressor
MEGKGOFH_01384 4.3e-133 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MEGKGOFH_01385 2.2e-84 yycN 2.3.1.128 K Acetyltransferase
MEGKGOFH_01386 7.3e-53 S DoxX-like family
MEGKGOFH_01387 7.6e-98 K Bacterial regulatory proteins, tetR family
MEGKGOFH_01388 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
MEGKGOFH_01389 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
MEGKGOFH_01390 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
MEGKGOFH_01391 5.2e-122 ydfS S Protein of unknown function (DUF421)
MEGKGOFH_01392 4.4e-118 ydfR S Protein of unknown function (DUF421)
MEGKGOFH_01394 6.3e-29
MEGKGOFH_01395 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
MEGKGOFH_01396 7.7e-55 traF CO Thioredoxin
MEGKGOFH_01397 8.8e-63 mhqP S DoxX
MEGKGOFH_01398 4e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MEGKGOFH_01399 1.1e-110 ydfN C nitroreductase
MEGKGOFH_01400 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEGKGOFH_01401 9.2e-147 K Bacterial transcription activator, effector binding domain
MEGKGOFH_01402 7.2e-116 S Protein of unknown function (DUF554)
MEGKGOFH_01403 2.2e-173 S Alpha/beta hydrolase family
MEGKGOFH_01404 0.0 ydfJ S drug exporters of the RND superfamily
MEGKGOFH_01405 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEGKGOFH_01406 8.8e-175 ydfH 2.7.13.3 T Histidine kinase
MEGKGOFH_01408 6.2e-41 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MEGKGOFH_01409 1e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MEGKGOFH_01410 5e-116 ydfE S Flavin reductase like domain
MEGKGOFH_01411 3.9e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEGKGOFH_01412 1.3e-160 ydfC EG EamA-like transporter family
MEGKGOFH_01413 6.1e-148 ydfB J GNAT acetyltransferase
MEGKGOFH_01414 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MEGKGOFH_01415 2.8e-57 arsR K transcriptional
MEGKGOFH_01416 3.2e-104 ydeS K Transcriptional regulator
MEGKGOFH_01417 1.2e-192 ydeR EGP Major facilitator Superfamily
MEGKGOFH_01418 5.1e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
MEGKGOFH_01419 1.8e-68 ydeP K Transcriptional regulator
MEGKGOFH_01420 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MEGKGOFH_01421 5.2e-56 K HxlR-like helix-turn-helix
MEGKGOFH_01422 4.7e-105 ydeN S Serine hydrolase
MEGKGOFH_01423 4.2e-74 maoC I N-terminal half of MaoC dehydratase
MEGKGOFH_01424 4.1e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEGKGOFH_01425 1.8e-153 ydeK EG -transporter
MEGKGOFH_01426 8.8e-85 K Transcriptional regulator C-terminal region
MEGKGOFH_01427 4.9e-15 ptsH G PTS HPr component phosphorylation site
MEGKGOFH_01428 1.5e-107
MEGKGOFH_01429 5.1e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MEGKGOFH_01430 1.4e-44 ydeH
MEGKGOFH_01431 1.8e-216 ydeG EGP Major facilitator superfamily
MEGKGOFH_01432 4.7e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEGKGOFH_01433 2e-163 ydeE K AraC family transcriptional regulator
MEGKGOFH_01434 9.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MEGKGOFH_01435 4.4e-163 rhaS5 K AraC-like ligand binding domain
MEGKGOFH_01436 7.5e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MEGKGOFH_01437 6.1e-79 carD K Transcription factor
MEGKGOFH_01438 8.7e-30 cspL K Cold shock
MEGKGOFH_01439 2.2e-190 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MEGKGOFH_01440 4.6e-42
MEGKGOFH_01441 3.4e-33 K Helix-turn-helix XRE-family like proteins
MEGKGOFH_01442 3.2e-103 M nucleic acid phosphodiester bond hydrolysis
MEGKGOFH_01443 4e-43 S LXG domain of WXG superfamily
MEGKGOFH_01444 1.1e-44
MEGKGOFH_01445 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
MEGKGOFH_01453 8.9e-83 ydcK S Belongs to the SprT family
MEGKGOFH_01454 0.0 yhgF K COG2183 Transcriptional accessory protein
MEGKGOFH_01455 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MEGKGOFH_01456 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEGKGOFH_01457 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MEGKGOFH_01458 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
MEGKGOFH_01459 7.1e-189 rsbU 3.1.3.3 KT phosphatase
MEGKGOFH_01460 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MEGKGOFH_01461 5.2e-57 rsbS T antagonist
MEGKGOFH_01462 3.7e-143 rsbR T Positive regulator of sigma-B
MEGKGOFH_01463 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MEGKGOFH_01464 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MEGKGOFH_01465 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEGKGOFH_01466 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MEGKGOFH_01467 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEGKGOFH_01468 2.9e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MEGKGOFH_01469 8.7e-260 ydbT S Membrane
MEGKGOFH_01470 2.1e-82 ydbS S Bacterial PH domain
MEGKGOFH_01471 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MEGKGOFH_01472 7.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEGKGOFH_01473 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MEGKGOFH_01474 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MEGKGOFH_01475 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEGKGOFH_01476 1.1e-18 S Fur-regulated basic protein B
MEGKGOFH_01477 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MEGKGOFH_01478 2.7e-52 ydbL
MEGKGOFH_01479 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MEGKGOFH_01480 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
MEGKGOFH_01481 9.7e-181 ydbI S AI-2E family transporter
MEGKGOFH_01482 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEGKGOFH_01483 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
MEGKGOFH_01484 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MEGKGOFH_01485 3.5e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MEGKGOFH_01486 2.3e-153 ydbD P Catalase
MEGKGOFH_01487 1.1e-62 ydbC S Domain of unknown function (DUF4937
MEGKGOFH_01488 8.9e-59 ydbB G Cupin domain
MEGKGOFH_01490 2.8e-38 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEGKGOFH_01491 7.1e-37
MEGKGOFH_01492 0.0 yjcD 3.6.4.12 L DNA helicase
MEGKGOFH_01493 2.9e-38 spoVIF S Stage VI sporulation protein F
MEGKGOFH_01496 1.9e-56 yjcA S Protein of unknown function (DUF1360)
MEGKGOFH_01497 3.2e-49 cotV S Spore Coat Protein X and V domain
MEGKGOFH_01498 7.4e-23 cotW
MEGKGOFH_01499 1.2e-67 cotX S Spore Coat Protein X and V domain
MEGKGOFH_01500 7.6e-96 cotY S Spore coat protein Z
MEGKGOFH_01501 4.4e-82 cotZ S Spore coat protein
MEGKGOFH_01502 2.1e-21 yjbX S Spore coat protein
MEGKGOFH_01503 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MEGKGOFH_01504 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MEGKGOFH_01505 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MEGKGOFH_01506 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MEGKGOFH_01507 2.6e-29 thiS H thiamine diphosphate biosynthetic process
MEGKGOFH_01508 4.1e-214 thiO 1.4.3.19 E Glycine oxidase
MEGKGOFH_01509 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MEGKGOFH_01510 8.4e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MEGKGOFH_01511 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEGKGOFH_01512 1.6e-126 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MEGKGOFH_01513 4e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MEGKGOFH_01514 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEGKGOFH_01515 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MEGKGOFH_01516 7.1e-62 yjbL S Belongs to the UPF0738 family
MEGKGOFH_01517 4.1e-101 yjbK S protein conserved in bacteria
MEGKGOFH_01518 3.2e-82 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MEGKGOFH_01519 3.7e-72 yjbI S Bacterial-like globin
MEGKGOFH_01520 6.8e-150 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MEGKGOFH_01523 0.0 pepF E oligoendopeptidase F
MEGKGOFH_01524 1.6e-221 yjbF S Competence protein
MEGKGOFH_01525 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MEGKGOFH_01526 6e-112 yjbE P Integral membrane protein TerC family
MEGKGOFH_01527 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEGKGOFH_01528 1.9e-49 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEGKGOFH_01529 8.6e-196 yjbB EGP Major Facilitator Superfamily
MEGKGOFH_01530 5.5e-172 oppF E Belongs to the ABC transporter superfamily
MEGKGOFH_01531 1.5e-197 oppD P Belongs to the ABC transporter superfamily
MEGKGOFH_01532 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEGKGOFH_01533 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEGKGOFH_01534 0.0 oppA E ABC transporter substrate-binding protein
MEGKGOFH_01535 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MEGKGOFH_01536 5.5e-146 yjbA S Belongs to the UPF0736 family
MEGKGOFH_01537 6.7e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEGKGOFH_01538 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEGKGOFH_01539 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MEGKGOFH_01540 7.2e-186 appF E Belongs to the ABC transporter superfamily
MEGKGOFH_01541 2.6e-183 appD P Belongs to the ABC transporter superfamily
MEGKGOFH_01542 3e-150 yjaZ O Zn-dependent protease
MEGKGOFH_01543 8.9e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEGKGOFH_01544 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEGKGOFH_01545 2.7e-22 yjzB
MEGKGOFH_01546 7.3e-26 comZ S ComZ
MEGKGOFH_01547 2.5e-183 med S Transcriptional activator protein med
MEGKGOFH_01548 1.5e-100 yjaV
MEGKGOFH_01549 3.1e-141 yjaU I carboxylic ester hydrolase activity
MEGKGOFH_01550 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MEGKGOFH_01551 9.5e-28 yjzC S YjzC-like protein
MEGKGOFH_01552 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEGKGOFH_01553 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MEGKGOFH_01554 1.1e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MEGKGOFH_01555 1.1e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MEGKGOFH_01556 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MEGKGOFH_01557 5.9e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MEGKGOFH_01558 9.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MEGKGOFH_01559 7.5e-46 norB G Major Facilitator Superfamily
MEGKGOFH_01560 1.4e-25 norB G Major Facilitator Superfamily
MEGKGOFH_01561 2.2e-268 yitY C D-arabinono-1,4-lactone oxidase
MEGKGOFH_01562 1.5e-22 pilT S Proteolipid membrane potential modulator
MEGKGOFH_01563 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MEGKGOFH_01564 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MEGKGOFH_01565 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MEGKGOFH_01567 3.4e-26 S Protein of unknown function (DUF3813)
MEGKGOFH_01568 5e-73 ipi S Intracellular proteinase inhibitor
MEGKGOFH_01569 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MEGKGOFH_01570 2.5e-158 yitS S protein conserved in bacteria
MEGKGOFH_01571 4.9e-309 nprB 3.4.24.28 E Peptidase M4
MEGKGOFH_01572 1.4e-44 yitR S Domain of unknown function (DUF3784)
MEGKGOFH_01573 4.7e-92
MEGKGOFH_01574 1.5e-58 K Transcriptional regulator PadR-like family
MEGKGOFH_01575 1.5e-97 S Sporulation delaying protein SdpA
MEGKGOFH_01576 1.8e-170
MEGKGOFH_01577 8.5e-94
MEGKGOFH_01578 1.3e-159 cvfB S protein conserved in bacteria
MEGKGOFH_01579 8.6e-55 yajQ S Belongs to the UPF0234 family
MEGKGOFH_01580 3.9e-179 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MEGKGOFH_01581 2.2e-142 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MEGKGOFH_01582 1e-70 yjcF S Acetyltransferase (GNAT) domain
MEGKGOFH_01583 2.4e-153 yitH K Acetyltransferase (GNAT) domain
MEGKGOFH_01584 5.4e-44 yitG EGP Major facilitator Superfamily
MEGKGOFH_01585 3.5e-169 yitG EGP Major facilitator Superfamily
MEGKGOFH_01586 5.6e-219 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MEGKGOFH_01587 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEGKGOFH_01588 1.9e-141 yitD 4.4.1.19 S synthase
MEGKGOFH_01589 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
MEGKGOFH_01590 2.5e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MEGKGOFH_01591 2.7e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MEGKGOFH_01592 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MEGKGOFH_01593 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MEGKGOFH_01594 4e-36 mcbG S Pentapeptide repeats (9 copies)
MEGKGOFH_01595 2.6e-269 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEGKGOFH_01596 1.3e-105 argO S Lysine exporter protein LysE YggA
MEGKGOFH_01597 9.1e-92 yisT S DinB family
MEGKGOFH_01598 5.7e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MEGKGOFH_01599 6.9e-184 purR K helix_turn _helix lactose operon repressor
MEGKGOFH_01600 1.2e-160 yisR K Transcriptional regulator
MEGKGOFH_01601 4e-243 yisQ V Mate efflux family protein
MEGKGOFH_01602 1.7e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MEGKGOFH_01603 4.7e-88 yizA S Damage-inducible protein DinB
MEGKGOFH_01604 0.0 asnO 6.3.5.4 E Asparagine synthase
MEGKGOFH_01605 1.3e-102 yisN S Protein of unknown function (DUF2777)
MEGKGOFH_01606 0.0 wprA O Belongs to the peptidase S8 family
MEGKGOFH_01607 3e-57 yisL S UPF0344 protein
MEGKGOFH_01608 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MEGKGOFH_01609 5.9e-174 cotH M Spore Coat
MEGKGOFH_01610 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MEGKGOFH_01611 1.9e-33 gerPA S Spore germination protein
MEGKGOFH_01612 4e-34 gerPB S cell differentiation
MEGKGOFH_01613 1.8e-54 gerPC S Spore germination protein
MEGKGOFH_01614 6.3e-24 gerPD S Spore germination protein
MEGKGOFH_01615 3e-66 gerPE S Spore germination protein GerPE
MEGKGOFH_01616 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MEGKGOFH_01617 3e-50 yisB V COG1403 Restriction endonuclease
MEGKGOFH_01618 3.6e-100 sbcC L COG0419 ATPase involved in DNA repair
MEGKGOFH_01619 0.0 sbcC L COG0419 ATPase involved in DNA repair
MEGKGOFH_01620 1.2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MEGKGOFH_01621 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MEGKGOFH_01622 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MEGKGOFH_01623 2.2e-78 yhjR S Rubrerythrin
MEGKGOFH_01624 2.1e-290 S Sugar transport-related sRNA regulator N-term
MEGKGOFH_01625 2.7e-121 S AAA domain
MEGKGOFH_01626 9.8e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MEGKGOFH_01627 1.1e-68 nin S Competence protein J (ComJ)
MEGKGOFH_01628 3.5e-71 nucA M Deoxyribonuclease NucA/NucB
MEGKGOFH_01629 3.6e-185 tlpC 2.7.13.3 NT chemotaxis protein
MEGKGOFH_01630 1.1e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MEGKGOFH_01631 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MEGKGOFH_01632 2.2e-63 hxlR K transcriptional
MEGKGOFH_01633 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGKGOFH_01634 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGKGOFH_01635 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MEGKGOFH_01636 5.7e-140 srfAD Q thioesterase
MEGKGOFH_01637 4.8e-224 EGP Major Facilitator Superfamily
MEGKGOFH_01638 1.4e-14 S YcxB-like protein
MEGKGOFH_01639 4.4e-48 S YcxB-like protein
MEGKGOFH_01640 7.6e-161 ycxC EG EamA-like transporter family
MEGKGOFH_01641 4.6e-252 ycxD K GntR family transcriptional regulator
MEGKGOFH_01642 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MEGKGOFH_01643 1.7e-114 yczE S membrane
MEGKGOFH_01644 4.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MEGKGOFH_01645 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MEGKGOFH_01646 3.5e-138 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MEGKGOFH_01647 4.9e-162 bsdA K LysR substrate binding domain
MEGKGOFH_01648 3.2e-98 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MEGKGOFH_01649 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MEGKGOFH_01650 4e-39 bsdD 4.1.1.61 S response to toxic substance
MEGKGOFH_01651 1.1e-83 yclD
MEGKGOFH_01652 1.2e-157 yclE 3.4.11.5 S Alpha beta hydrolase
MEGKGOFH_01653 4.7e-266 dtpT E amino acid peptide transporter
MEGKGOFH_01654 1.3e-307 yclG M Pectate lyase superfamily protein
MEGKGOFH_01656 1.5e-281 gerKA EG Spore germination protein
MEGKGOFH_01657 3.7e-232 gerKC S spore germination
MEGKGOFH_01658 3.8e-199 gerKB F Spore germination protein
MEGKGOFH_01659 1.9e-121 yclH P ABC transporter
MEGKGOFH_01660 1.5e-203 yclI V ABC transporter (permease) YclI
MEGKGOFH_01661 2.3e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_01662 4.9e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MEGKGOFH_01663 5.2e-71 S aspartate phosphatase
MEGKGOFH_01666 2.8e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
MEGKGOFH_01667 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEGKGOFH_01668 7.6e-144 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEGKGOFH_01669 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MEGKGOFH_01670 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MEGKGOFH_01671 1.4e-251 ycnB EGP Major facilitator Superfamily
MEGKGOFH_01672 6.5e-154 ycnC K Transcriptional regulator
MEGKGOFH_01673 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MEGKGOFH_01674 1.6e-45 ycnE S Monooxygenase
MEGKGOFH_01675 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MEGKGOFH_01676 1.1e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MEGKGOFH_01677 9.1e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEGKGOFH_01678 1.7e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MEGKGOFH_01679 6.1e-149 glcU U Glucose uptake
MEGKGOFH_01680 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_01681 7.8e-98 ycnI S protein conserved in bacteria
MEGKGOFH_01682 9.3e-308 ycnJ P protein, homolog of Cu resistance protein CopC
MEGKGOFH_01683 1.8e-104 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MEGKGOFH_01684 3.4e-53
MEGKGOFH_01685 2.9e-236 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MEGKGOFH_01686 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MEGKGOFH_01687 5.3e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MEGKGOFH_01688 7.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MEGKGOFH_01689 1.2e-89 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MEGKGOFH_01690 6.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MEGKGOFH_01691 1.2e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MEGKGOFH_01693 4.5e-109 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MEGKGOFH_01694 2.7e-16 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MEGKGOFH_01695 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
MEGKGOFH_01696 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MEGKGOFH_01697 3.1e-147 ycsI S Belongs to the D-glutamate cyclase family
MEGKGOFH_01698 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MEGKGOFH_01699 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MEGKGOFH_01700 6e-132 kipR K Transcriptional regulator
MEGKGOFH_01701 4.9e-119 ycsK E anatomical structure formation involved in morphogenesis
MEGKGOFH_01703 1.4e-49 yczJ S biosynthesis
MEGKGOFH_01704 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MEGKGOFH_01705 2.7e-171 ydhF S Oxidoreductase
MEGKGOFH_01706 0.0 mtlR K transcriptional regulator, MtlR
MEGKGOFH_01707 2.1e-293 ydaB IQ acyl-CoA ligase
MEGKGOFH_01708 9e-99 ydaC Q Methyltransferase domain
MEGKGOFH_01709 1.2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_01710 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MEGKGOFH_01711 1.3e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MEGKGOFH_01712 6.8e-77 ydaG 1.4.3.5 S general stress protein
MEGKGOFH_01713 1.7e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MEGKGOFH_01714 2.5e-46 ydzA EGP Major facilitator Superfamily
MEGKGOFH_01715 2.5e-74 lrpC K Transcriptional regulator
MEGKGOFH_01716 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEGKGOFH_01717 2.4e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MEGKGOFH_01718 1.6e-149 ydaK T Diguanylate cyclase, GGDEF domain
MEGKGOFH_01719 7.5e-242 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MEGKGOFH_01720 5e-63 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MEGKGOFH_01721 1.3e-232 ydaM M Glycosyl transferase family group 2
MEGKGOFH_01722 0.0 ydaN S Bacterial cellulose synthase subunit
MEGKGOFH_01723 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEGKGOFH_01724 5.6e-236 cinA 3.5.1.42 S Belongs to the CinA family
MEGKGOFH_01725 2.3e-64 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEGKGOFH_01726 1.3e-114 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEGKGOFH_01727 1e-215 pbpX V Beta-lactamase
MEGKGOFH_01728 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MEGKGOFH_01729 1.9e-152 ymdB S protein conserved in bacteria
MEGKGOFH_01730 1.2e-36 spoVS S Stage V sporulation protein S
MEGKGOFH_01731 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MEGKGOFH_01732 7.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MEGKGOFH_01733 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MEGKGOFH_01734 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MEGKGOFH_01735 2.2e-88 cotE S Spore coat protein
MEGKGOFH_01736 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEGKGOFH_01737 2.7e-261 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEGKGOFH_01738 1.1e-74 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEGKGOFH_01739 1.1e-67 S Regulatory protein YrvL
MEGKGOFH_01741 3.9e-96 ymcC S Membrane
MEGKGOFH_01742 4.4e-109 pksA K Transcriptional regulator
MEGKGOFH_01743 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
MEGKGOFH_01744 7.5e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MEGKGOFH_01746 3.9e-184 pksD Q Acyl transferase domain
MEGKGOFH_01747 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MEGKGOFH_01748 1.4e-37 acpK IQ Phosphopantetheine attachment site
MEGKGOFH_01749 1.3e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEGKGOFH_01750 1.5e-244 pksG 2.3.3.10 I synthase
MEGKGOFH_01751 9.4e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
MEGKGOFH_01752 2.3e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
MEGKGOFH_01753 0.0 rhiB IQ polyketide synthase
MEGKGOFH_01754 0.0 pfaA Q Polyketide synthase of type I
MEGKGOFH_01755 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
MEGKGOFH_01756 0.0 dhbF IQ polyketide synthase
MEGKGOFH_01757 0.0 dhbF IQ polyketide synthase
MEGKGOFH_01758 0.0 pks13 HQ Beta-ketoacyl synthase
MEGKGOFH_01759 6.9e-231 cypA C Cytochrome P450
MEGKGOFH_01760 4.4e-61 ymzB
MEGKGOFH_01761 9.5e-163 ymaE S Metallo-beta-lactamase superfamily
MEGKGOFH_01762 1.7e-251 aprX O Belongs to the peptidase S8 family
MEGKGOFH_01763 1.9e-07 K Transcriptional regulator
MEGKGOFH_01764 2.1e-126 ymaC S Replication protein
MEGKGOFH_01765 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
MEGKGOFH_01766 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MEGKGOFH_01767 2.1e-49 ebrA P Small Multidrug Resistance protein
MEGKGOFH_01769 2.1e-46 ymaF S YmaF family
MEGKGOFH_01770 6e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEGKGOFH_01771 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MEGKGOFH_01772 4.1e-22
MEGKGOFH_01773 4.5e-22 ymzA
MEGKGOFH_01774 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MEGKGOFH_01775 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEGKGOFH_01776 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEGKGOFH_01777 2e-109 ymaB
MEGKGOFH_01778 8.8e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MEGKGOFH_01779 7.6e-172 spoVK O stage V sporulation protein K
MEGKGOFH_01780 7.9e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEGKGOFH_01781 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MEGKGOFH_01782 1.1e-68 glnR K transcriptional
MEGKGOFH_01783 2.4e-57 yknT
MEGKGOFH_01784 7.4e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MEGKGOFH_01785 5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MEGKGOFH_01786 6.9e-245 moeA 2.10.1.1 H molybdopterin
MEGKGOFH_01787 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MEGKGOFH_01788 7.3e-52 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MEGKGOFH_01789 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MEGKGOFH_01790 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MEGKGOFH_01791 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MEGKGOFH_01792 1e-117 yknW S Yip1 domain
MEGKGOFH_01793 4e-156 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MEGKGOFH_01794 8.7e-60 macB V ABC transporter, ATP-binding protein
MEGKGOFH_01795 8.3e-51 macB V ABC transporter, ATP-binding protein
MEGKGOFH_01796 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MEGKGOFH_01797 3.1e-136 fruR K Transcriptional regulator
MEGKGOFH_01798 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MEGKGOFH_01799 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MEGKGOFH_01800 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MEGKGOFH_01801 8.1e-39 ykoA
MEGKGOFH_01802 5.7e-158 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MEGKGOFH_01803 9.2e-121 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MEGKGOFH_01804 2.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEGKGOFH_01805 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MEGKGOFH_01806 1.1e-12 S Uncharacterized protein YkpC
MEGKGOFH_01807 7.7e-183 mreB D Rod-share determining protein MreBH
MEGKGOFH_01808 1.5e-43 abrB K of stationary sporulation gene expression
MEGKGOFH_01809 4.6e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MEGKGOFH_01810 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MEGKGOFH_01811 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
MEGKGOFH_01812 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MEGKGOFH_01813 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEGKGOFH_01814 8.2e-31 ykzG S Belongs to the UPF0356 family
MEGKGOFH_01815 5.5e-147 ykrA S hydrolases of the HAD superfamily
MEGKGOFH_01816 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEGKGOFH_01818 2e-115 recN L Putative cell-wall binding lipoprotein
MEGKGOFH_01819 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MEGKGOFH_01820 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MEGKGOFH_01821 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEGKGOFH_01822 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MEGKGOFH_01823 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MEGKGOFH_01824 1.3e-276 speA 4.1.1.19 E Arginine
MEGKGOFH_01825 2e-42 yktA S Belongs to the UPF0223 family
MEGKGOFH_01826 2.1e-117 yktB S Belongs to the UPF0637 family
MEGKGOFH_01827 7.2e-26 ykzI
MEGKGOFH_01828 2.5e-149 suhB 3.1.3.25 G Inositol monophosphatase
MEGKGOFH_01829 6.9e-78 ykzC S Acetyltransferase (GNAT) family
MEGKGOFH_01830 1.9e-169 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MEGKGOFH_01831 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MEGKGOFH_01832 0.0 ylaA
MEGKGOFH_01833 2.7e-42 ylaB
MEGKGOFH_01834 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MEGKGOFH_01835 7e-12 sigC S Putative zinc-finger
MEGKGOFH_01836 2.6e-37 ylaE
MEGKGOFH_01837 8.2e-22 S Family of unknown function (DUF5325)
MEGKGOFH_01838 0.0 typA T GTP-binding protein TypA
MEGKGOFH_01839 4.2e-47 ylaH S YlaH-like protein
MEGKGOFH_01840 2.5e-32 ylaI S protein conserved in bacteria
MEGKGOFH_01841 8.9e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MEGKGOFH_01842 5.7e-54 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MEGKGOFH_01843 5e-159 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MEGKGOFH_01844 4.6e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MEGKGOFH_01845 2.3e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
MEGKGOFH_01846 8.7e-44 ylaN S Belongs to the UPF0358 family
MEGKGOFH_01847 2.5e-212 ftsW D Belongs to the SEDS family
MEGKGOFH_01848 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MEGKGOFH_01849 3.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MEGKGOFH_01850 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MEGKGOFH_01851 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MEGKGOFH_01852 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MEGKGOFH_01853 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MEGKGOFH_01854 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MEGKGOFH_01855 3e-167 ctaG S cytochrome c oxidase
MEGKGOFH_01856 7e-62 ylbA S YugN-like family
MEGKGOFH_01857 2.6e-74 ylbB T COG0517 FOG CBS domain
MEGKGOFH_01858 9.6e-200 ylbC S protein with SCP PR1 domains
MEGKGOFH_01859 4.1e-63 ylbD S Putative coat protein
MEGKGOFH_01860 6.7e-37 ylbE S YlbE-like protein
MEGKGOFH_01861 1.8e-75 ylbF S Belongs to the UPF0342 family
MEGKGOFH_01862 3.7e-38 ylbG S UPF0298 protein
MEGKGOFH_01863 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
MEGKGOFH_01864 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEGKGOFH_01865 1.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
MEGKGOFH_01866 2.9e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
MEGKGOFH_01867 6.8e-187 ylbL T Belongs to the peptidase S16 family
MEGKGOFH_01868 2.8e-235 ylbM S Belongs to the UPF0348 family
MEGKGOFH_01870 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
MEGKGOFH_01871 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MEGKGOFH_01872 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MEGKGOFH_01873 1.5e-88 ylbP K n-acetyltransferase
MEGKGOFH_01874 6.8e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEGKGOFH_01875 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MEGKGOFH_01876 2.9e-78 mraZ K Belongs to the MraZ family
MEGKGOFH_01877 3.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEGKGOFH_01878 3.7e-44 ftsL D Essential cell division protein
MEGKGOFH_01879 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MEGKGOFH_01880 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MEGKGOFH_01881 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEGKGOFH_01882 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEGKGOFH_01883 1.7e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEGKGOFH_01884 5.7e-186 spoVE D Belongs to the SEDS family
MEGKGOFH_01885 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEGKGOFH_01886 5.3e-167 murB 1.3.1.98 M cell wall formation
MEGKGOFH_01887 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MEGKGOFH_01888 7.8e-08
MEGKGOFH_01890 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MEGKGOFH_01891 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MEGKGOFH_01892 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MEGKGOFH_01893 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MEGKGOFH_01894 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEGKGOFH_01895 0.0 ydiF S ABC transporter
MEGKGOFH_01896 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MEGKGOFH_01897 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEGKGOFH_01898 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MEGKGOFH_01899 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MEGKGOFH_01900 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MEGKGOFH_01901 7.9e-129 ydiL S CAAX protease self-immunity
MEGKGOFH_01902 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEGKGOFH_01903 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEGKGOFH_01904 5.5e-40 ydjC S Abhydrolase domain containing 18
MEGKGOFH_01905 4.1e-110 ydjC S alpha beta
MEGKGOFH_01906 0.0 K NB-ARC domain
MEGKGOFH_01907 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
MEGKGOFH_01908 1.1e-253 gutA G MFS/sugar transport protein
MEGKGOFH_01909 3.4e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MEGKGOFH_01910 5.6e-113 pspA KT Phage shock protein A
MEGKGOFH_01911 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEGKGOFH_01912 1.2e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MEGKGOFH_01913 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
MEGKGOFH_01914 2.6e-194 S Ion transport 2 domain protein
MEGKGOFH_01915 4.5e-258 iolT EGP Major facilitator Superfamily
MEGKGOFH_01916 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MEGKGOFH_01917 4.5e-64 ydjM M Lytic transglycolase
MEGKGOFH_01918 6.5e-127 ydjN U Involved in the tonB-independent uptake of proteins
MEGKGOFH_01920 1.4e-34 ydjO S Cold-inducible protein YdjO
MEGKGOFH_01921 9.5e-160 ydjP I Alpha/beta hydrolase family
MEGKGOFH_01922 7.4e-144 yeaA S Protein of unknown function (DUF4003)
MEGKGOFH_01923 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MEGKGOFH_01924 7.5e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MEGKGOFH_01925 2.4e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MEGKGOFH_01926 1.7e-176 yeaC S COG0714 MoxR-like ATPases
MEGKGOFH_01927 2.8e-128 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MEGKGOFH_01928 6.2e-85 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MEGKGOFH_01929 1e-18 yebA E COG1305 Transglutaminase-like enzymes
MEGKGOFH_01930 0.0 yebA E COG1305 Transglutaminase-like enzymes
MEGKGOFH_01931 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MEGKGOFH_01932 6.4e-88 K Belongs to the sigma-70 factor family. ECF subfamily
MEGKGOFH_01933 7e-246 S Domain of unknown function (DUF4179)
MEGKGOFH_01934 1.1e-210 pbuG S permease
MEGKGOFH_01935 2.3e-118 yebC M Membrane
MEGKGOFH_01937 4e-93 yebE S UPF0316 protein
MEGKGOFH_01938 8e-28 yebG S NETI protein
MEGKGOFH_01939 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEGKGOFH_01940 1.3e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEGKGOFH_01941 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MEGKGOFH_01942 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MEGKGOFH_01943 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEGKGOFH_01944 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEGKGOFH_01945 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEGKGOFH_01946 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEGKGOFH_01947 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MEGKGOFH_01948 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MEGKGOFH_01949 6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MEGKGOFH_01950 2e-233 purD 6.3.4.13 F Belongs to the GARS family
MEGKGOFH_01951 1e-72 K helix_turn_helix ASNC type
MEGKGOFH_01952 7e-226 yjeH E Amino acid permease
MEGKGOFH_01953 2.7e-27 S Protein of unknown function (DUF2892)
MEGKGOFH_01954 0.0 yerA 3.5.4.2 F adenine deaminase
MEGKGOFH_01955 6.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
MEGKGOFH_01956 2.4e-50 yerC S protein conserved in bacteria
MEGKGOFH_01957 6.7e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MEGKGOFH_01958 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MEGKGOFH_01959 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MEGKGOFH_01960 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEGKGOFH_01961 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MEGKGOFH_01962 3.2e-197 yerI S homoserine kinase type II (protein kinase fold)
MEGKGOFH_01963 6.1e-123 sapB S MgtC SapB transporter
MEGKGOFH_01964 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEGKGOFH_01965 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEGKGOFH_01966 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEGKGOFH_01967 6.8e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEGKGOFH_01968 1.6e-138 yerO K Transcriptional regulator
MEGKGOFH_01969 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MEGKGOFH_01970 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MEGKGOFH_01971 1.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEGKGOFH_01972 2.5e-77 K Helix-turn-helix
MEGKGOFH_01973 1.8e-102 metQ P Belongs to the NlpA lipoprotein family
MEGKGOFH_01974 9.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MEGKGOFH_01975 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MEGKGOFH_01976 9.1e-245 sufD O assembly protein SufD
MEGKGOFH_01977 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEGKGOFH_01978 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MEGKGOFH_01979 3.5e-271 sufB O FeS cluster assembly
MEGKGOFH_01980 5e-14 L helicase
MEGKGOFH_01981 6.4e-279 L AAA ATPase domain
MEGKGOFH_01982 2.1e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
MEGKGOFH_01983 5.5e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEGKGOFH_01984 1e-41
MEGKGOFH_01986 5.8e-208 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MEGKGOFH_01987 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MEGKGOFH_01988 8.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MEGKGOFH_01989 1.2e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MEGKGOFH_01990 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
MEGKGOFH_01991 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
MEGKGOFH_01992 3.3e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MEGKGOFH_01993 3.3e-135 yurK K UTRA
MEGKGOFH_01994 5e-204 msmX P Belongs to the ABC transporter superfamily
MEGKGOFH_01995 2.4e-169 bsn L Ribonuclease
MEGKGOFH_01996 4.4e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MEGKGOFH_01997 3.2e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MEGKGOFH_01999 3.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MEGKGOFH_02000 3.1e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MEGKGOFH_02001 9.9e-107 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MEGKGOFH_02002 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MEGKGOFH_02003 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MEGKGOFH_02004 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MEGKGOFH_02005 1.9e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MEGKGOFH_02006 6.7e-224 pbuX F xanthine
MEGKGOFH_02007 1.4e-232 pbuX F Permease family
MEGKGOFH_02008 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
MEGKGOFH_02009 1.6e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MEGKGOFH_02010 3e-62 yunG
MEGKGOFH_02011 4.3e-171 yunF S Protein of unknown function DUF72
MEGKGOFH_02012 1.7e-140 yunE S membrane transporter protein
MEGKGOFH_02013 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MEGKGOFH_02014 5.3e-47 yunC S Domain of unknown function (DUF1805)
MEGKGOFH_02015 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
MEGKGOFH_02016 4.5e-196 lytH M Peptidase, M23
MEGKGOFH_02017 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MEGKGOFH_02018 2.7e-109 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MEGKGOFH_02019 9.7e-48 yutD S protein conserved in bacteria
MEGKGOFH_02020 2.5e-74 yutE S Protein of unknown function DUF86
MEGKGOFH_02021 4.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MEGKGOFH_02022 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MEGKGOFH_02023 2.9e-198 yutH S Spore coat protein
MEGKGOFH_02024 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
MEGKGOFH_02025 4e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MEGKGOFH_02026 1.2e-171 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEGKGOFH_02027 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MEGKGOFH_02028 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MEGKGOFH_02029 8.7e-56 yuzD S protein conserved in bacteria
MEGKGOFH_02030 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MEGKGOFH_02031 3.2e-39 yuzB S Belongs to the UPF0349 family
MEGKGOFH_02032 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MEGKGOFH_02033 1.8e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MEGKGOFH_02034 3.7e-63 erpA S Belongs to the HesB IscA family
MEGKGOFH_02036 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEGKGOFH_02037 2.2e-116 paiB K Putative FMN-binding domain
MEGKGOFH_02038 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEGKGOFH_02040 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
MEGKGOFH_02041 2.4e-193 yumB 1.6.99.3 C NADH dehydrogenase
MEGKGOFH_02042 9.2e-22 yumB 1.6.99.3 C NADH dehydrogenase
MEGKGOFH_02043 8.4e-27 yuiB S Putative membrane protein
MEGKGOFH_02044 1.4e-116 yuiC S protein conserved in bacteria
MEGKGOFH_02045 9.7e-46 yuiD S protein conserved in bacteria
MEGKGOFH_02046 4.5e-23 yuiD S protein conserved in bacteria
MEGKGOFH_02047 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MEGKGOFH_02048 3.9e-211 yuiF S antiporter
MEGKGOFH_02049 4.4e-93 bioY S Biotin biosynthesis protein
MEGKGOFH_02050 2.2e-121 yuiH S Oxidoreductase molybdopterin binding domain
MEGKGOFH_02051 1.5e-166 besA S Putative esterase
MEGKGOFH_02052 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGKGOFH_02053 1.2e-224 entC 5.4.4.2 HQ Isochorismate synthase
MEGKGOFH_02054 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MEGKGOFH_02055 5.2e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MEGKGOFH_02056 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGKGOFH_02057 5e-36 mbtH S MbtH-like protein
MEGKGOFH_02058 9.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
MEGKGOFH_02059 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MEGKGOFH_02060 1.5e-228 yukF QT Transcriptional regulator
MEGKGOFH_02061 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MEGKGOFH_02062 2.2e-47 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MEGKGOFH_02063 7.8e-155 gltC K Transcriptional regulator
MEGKGOFH_02064 1.2e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEGKGOFH_02065 1.3e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEGKGOFH_02066 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MEGKGOFH_02067 1e-120 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGKGOFH_02068 3.7e-40 yoxC S Bacterial protein of unknown function (DUF948)
MEGKGOFH_02069 2.4e-128 yoxB
MEGKGOFH_02070 1.9e-84 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MEGKGOFH_02071 3.4e-242 S Arylsulfotransferase (ASST)
MEGKGOFH_02072 1.9e-126 3.1.1.3 I Lipase (class 3)
MEGKGOFH_02073 7.6e-233 yoaB EGP Major facilitator Superfamily
MEGKGOFH_02074 1.5e-277 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MEGKGOFH_02075 6.8e-184 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEGKGOFH_02076 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEGKGOFH_02077 1.9e-33 yoaF
MEGKGOFH_02078 7.9e-08 ywlA S Uncharacterised protein family (UPF0715)
MEGKGOFH_02079 2.6e-13
MEGKGOFH_02080 8.3e-12 S Protein of unknown function (DUF4025)
MEGKGOFH_02081 1.7e-179 mcpU NT methyl-accepting chemotaxis protein
MEGKGOFH_02082 3.7e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MEGKGOFH_02083 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MEGKGOFH_02084 2.3e-111 yoaK S Membrane
MEGKGOFH_02085 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MEGKGOFH_02086 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
MEGKGOFH_02088 8.9e-77 oxdC 4.1.1.2 G Oxalate decarboxylase
MEGKGOFH_02089 8.8e-93 oxdC 4.1.1.2 G Oxalate decarboxylase
MEGKGOFH_02092 9.3e-132 yoaP 3.1.3.18 K YoaP-like
MEGKGOFH_02093 7e-52 yoaQ S Evidence 4 Homologs of previously reported genes of
MEGKGOFH_02095 1e-87
MEGKGOFH_02096 2.1e-171 yoaR V vancomycin resistance protein
MEGKGOFH_02097 2.8e-74 yoaS S Protein of unknown function (DUF2975)
MEGKGOFH_02098 1.6e-36 yozG K Transcriptional regulator
MEGKGOFH_02099 6.3e-148 yoaT S Protein of unknown function (DUF817)
MEGKGOFH_02100 3.3e-158 yoaU K LysR substrate binding domain
MEGKGOFH_02101 3.7e-157 yijE EG EamA-like transporter family
MEGKGOFH_02102 5.4e-77 yoaW
MEGKGOFH_02103 8.1e-97 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MEGKGOFH_02104 5.3e-167 bla 3.5.2.6 V beta-lactamase
MEGKGOFH_02107 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MEGKGOFH_02108 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MEGKGOFH_02109 8.8e-37 S TM2 domain
MEGKGOFH_02110 1.9e-07 K Helix-turn-helix
MEGKGOFH_02113 6.8e-48 FG Scavenger mRNA decapping enzyme C-term binding
MEGKGOFH_02120 1.8e-15 K Cro/C1-type HTH DNA-binding domain
MEGKGOFH_02121 1.1e-116
MEGKGOFH_02122 8.7e-32 isp O Subtilase family
MEGKGOFH_02129 1.3e-28 S Bacillus cereus group antimicrobial protein
MEGKGOFH_02131 1.1e-61 yoqH M LysM domain
MEGKGOFH_02135 9.2e-206 S aspartate phosphatase
MEGKGOFH_02137 1.4e-79 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEGKGOFH_02138 2.2e-34 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEGKGOFH_02139 1.1e-21 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEGKGOFH_02141 7.9e-46
MEGKGOFH_02143 1.5e-19
MEGKGOFH_02144 6.5e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MEGKGOFH_02145 1.1e-90 yokH G SMI1 / KNR4 family
MEGKGOFH_02146 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MEGKGOFH_02147 0.0 yobO M Pectate lyase superfamily protein
MEGKGOFH_02148 3.8e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MEGKGOFH_02149 1.4e-133 yobQ K helix_turn_helix, arabinose operon control protein
MEGKGOFH_02150 3.1e-141 yobR 2.3.1.1 J FR47-like protein
MEGKGOFH_02151 1.3e-97 yobS K Transcriptional regulator
MEGKGOFH_02152 9.5e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MEGKGOFH_02153 3.4e-88 yobU K Bacterial transcription activator, effector binding domain
MEGKGOFH_02154 7.1e-175 yobV K WYL domain
MEGKGOFH_02155 8.8e-93 yobW
MEGKGOFH_02156 1e-51 czrA K transcriptional
MEGKGOFH_02157 1.1e-116 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MEGKGOFH_02158 6.5e-76 yozB S membrane
MEGKGOFH_02159 2.1e-143
MEGKGOFH_02160 1.6e-93 yocC
MEGKGOFH_02161 2.4e-186 yocD 3.4.17.13 V peptidase S66
MEGKGOFH_02162 1e-201 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MEGKGOFH_02163 7.1e-198 desK 2.7.13.3 T Histidine kinase
MEGKGOFH_02164 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEGKGOFH_02165 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
MEGKGOFH_02166 0.0 recQ 3.6.4.12 L DNA helicase
MEGKGOFH_02167 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MEGKGOFH_02168 3.3e-83 dksA T general stress protein
MEGKGOFH_02169 8.4e-54 yocL
MEGKGOFH_02170 6.2e-32
MEGKGOFH_02171 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
MEGKGOFH_02172 1.1e-40 yozN
MEGKGOFH_02173 1.9e-36 yocN
MEGKGOFH_02174 4.2e-56 yozO S Bacterial PH domain
MEGKGOFH_02176 2.2e-14 sspO S Belongs to the SspO family
MEGKGOFH_02177 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MEGKGOFH_02178 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MEGKGOFH_02180 3.1e-08 sspN S Small acid-soluble spore protein N family
MEGKGOFH_02181 1.1e-34 tlp S Belongs to the Tlp family
MEGKGOFH_02182 2.6e-14 yneP S thioesterase
MEGKGOFH_02183 2.9e-47 yneP S thioesterase
MEGKGOFH_02184 1.3e-53 yneQ
MEGKGOFH_02185 4.1e-49 yneR S Belongs to the HesB IscA family
MEGKGOFH_02186 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEGKGOFH_02187 2.5e-68 yccU S CoA-binding protein
MEGKGOFH_02188 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEGKGOFH_02189 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEGKGOFH_02190 2.3e-12
MEGKGOFH_02191 1.3e-57 ynfC
MEGKGOFH_02192 5.3e-251 agcS E Sodium alanine symporter
MEGKGOFH_02193 8.4e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MEGKGOFH_02195 5.7e-241 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MEGKGOFH_02196 1.5e-294 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MEGKGOFH_02197 1.6e-79 yngA S membrane
MEGKGOFH_02198 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MEGKGOFH_02199 1.1e-24 yngC S membrane-associated protein
MEGKGOFH_02200 5.9e-55 yngC S membrane-associated protein
MEGKGOFH_02201 2.5e-233 nrnB S phosphohydrolase (DHH superfamily)
MEGKGOFH_02202 9.1e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MEGKGOFH_02203 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MEGKGOFH_02204 2.3e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MEGKGOFH_02205 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MEGKGOFH_02206 2.6e-180 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MEGKGOFH_02207 1.1e-31 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MEGKGOFH_02208 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MEGKGOFH_02209 1.4e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MEGKGOFH_02210 1e-303 yngK T Glycosyl hydrolase-like 10
MEGKGOFH_02211 6.2e-64 yngL S Protein of unknown function (DUF1360)
MEGKGOFH_02212 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MEGKGOFH_02213 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGKGOFH_02214 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGKGOFH_02215 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGKGOFH_02216 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEGKGOFH_02217 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MEGKGOFH_02218 6.2e-190 yoxA 5.1.3.3 G Aldose 1-epimerase
MEGKGOFH_02219 2.3e-246 yoeA V MATE efflux family protein
MEGKGOFH_02220 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
MEGKGOFH_02222 2.2e-96 L Integrase
MEGKGOFH_02223 3e-34 yoeD G Helix-turn-helix domain
MEGKGOFH_02224 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MEGKGOFH_02225 2.5e-158 gltR1 K Transcriptional regulator
MEGKGOFH_02226 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MEGKGOFH_02227 5.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MEGKGOFH_02228 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MEGKGOFH_02229 2.1e-199 ysfB KT regulator
MEGKGOFH_02230 2.3e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
MEGKGOFH_02231 1.1e-256 glcF C Glycolate oxidase
MEGKGOFH_02232 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
MEGKGOFH_02233 0.0 cstA T Carbon starvation protein
MEGKGOFH_02234 1.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MEGKGOFH_02235 3.8e-143 araQ G transport system permease
MEGKGOFH_02236 1.4e-167 araP G carbohydrate transport
MEGKGOFH_02237 1.8e-245 araN G carbohydrate transport
MEGKGOFH_02238 4.4e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MEGKGOFH_02239 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MEGKGOFH_02240 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MEGKGOFH_02241 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MEGKGOFH_02242 1.7e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MEGKGOFH_02243 1.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MEGKGOFH_02244 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
MEGKGOFH_02245 9.2e-68 ysdB S Sigma-w pathway protein YsdB
MEGKGOFH_02246 7.5e-45 ysdA S Membrane
MEGKGOFH_02247 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEGKGOFH_02248 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MEGKGOFH_02249 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEGKGOFH_02251 2.3e-114 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MEGKGOFH_02252 3.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MEGKGOFH_02253 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
MEGKGOFH_02254 0.0 lytS 2.7.13.3 T Histidine kinase
MEGKGOFH_02255 3.1e-147 ysaA S HAD-hyrolase-like
MEGKGOFH_02256 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEGKGOFH_02258 3.8e-159 ytxC S YtxC-like family
MEGKGOFH_02259 4.9e-111 ytxB S SNARE associated Golgi protein
MEGKGOFH_02260 3e-173 dnaI L Primosomal protein DnaI
MEGKGOFH_02261 3.5e-266 dnaB L Membrane attachment protein
MEGKGOFH_02262 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEGKGOFH_02263 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MEGKGOFH_02264 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEGKGOFH_02265 9.9e-67 ytcD K Transcriptional regulator
MEGKGOFH_02266 1.6e-147 ytbD EGP Major facilitator Superfamily
MEGKGOFH_02267 2.9e-38 ytbD EGP Major facilitator Superfamily
MEGKGOFH_02268 8.9e-161 ytbE S reductase
MEGKGOFH_02269 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEGKGOFH_02270 1.1e-107 ytaF P Probably functions as a manganese efflux pump
MEGKGOFH_02271 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MEGKGOFH_02272 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEGKGOFH_02273 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MEGKGOFH_02274 2.3e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_02275 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MEGKGOFH_02276 4.1e-242 icd 1.1.1.42 C isocitrate
MEGKGOFH_02277 1.4e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
MEGKGOFH_02278 2.3e-70 yeaL S membrane
MEGKGOFH_02279 2.6e-192 ytvI S sporulation integral membrane protein YtvI
MEGKGOFH_02280 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MEGKGOFH_02281 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MEGKGOFH_02282 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MEGKGOFH_02283 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MEGKGOFH_02284 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEGKGOFH_02285 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MEGKGOFH_02286 0.0 dnaE 2.7.7.7 L DNA polymerase
MEGKGOFH_02287 3.2e-56 ytrH S Sporulation protein YtrH
MEGKGOFH_02288 8.2e-69 ytrI
MEGKGOFH_02289 9.2e-29
MEGKGOFH_02290 2.3e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MEGKGOFH_02291 3.1e-47 ytpI S YtpI-like protein
MEGKGOFH_02292 8e-241 ytoI K transcriptional regulator containing CBS domains
MEGKGOFH_02293 1.9e-156 ytnM S membrane transporter protein
MEGKGOFH_02294 2.8e-235 ytnL 3.5.1.47 E hydrolase activity
MEGKGOFH_02295 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
MEGKGOFH_02296 1.7e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEGKGOFH_02297 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
MEGKGOFH_02298 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEGKGOFH_02299 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MEGKGOFH_02300 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
MEGKGOFH_02301 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
MEGKGOFH_02302 3.9e-148 tcyK M Bacterial periplasmic substrate-binding proteins
MEGKGOFH_02303 2.6e-141 tcyK ET Bacterial periplasmic substrate-binding proteins
MEGKGOFH_02304 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
MEGKGOFH_02305 5.5e-172 ytlI K LysR substrate binding domain
MEGKGOFH_02306 1.7e-130 ytkL S Belongs to the UPF0173 family
MEGKGOFH_02307 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_02309 2e-266 argH 4.3.2.1 E argininosuccinate lyase
MEGKGOFH_02310 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEGKGOFH_02311 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MEGKGOFH_02312 4.1e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEGKGOFH_02313 7e-165 ytxK 2.1.1.72 L DNA methylase
MEGKGOFH_02314 7.1e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEGKGOFH_02315 8.7e-70 ytfJ S Sporulation protein YtfJ
MEGKGOFH_02316 9.2e-87 ytfI S Protein of unknown function (DUF2953)
MEGKGOFH_02317 4.2e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MEGKGOFH_02318 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
MEGKGOFH_02319 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MEGKGOFH_02320 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MEGKGOFH_02321 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEGKGOFH_02322 4.1e-90 ypuF S Domain of unknown function (DUF309)
MEGKGOFH_02323 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEGKGOFH_02324 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEGKGOFH_02325 7.6e-97 ypuI S Protein of unknown function (DUF3907)
MEGKGOFH_02326 2e-211 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MEGKGOFH_02327 3.5e-103 spmA S Spore maturation protein
MEGKGOFH_02328 5.4e-87 spmB S Spore maturation protein
MEGKGOFH_02329 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEGKGOFH_02330 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MEGKGOFH_02331 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MEGKGOFH_02332 8.8e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MEGKGOFH_02333 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_02334 0.0 resE 2.7.13.3 T Histidine kinase
MEGKGOFH_02335 3.5e-80 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MEGKGOFH_02336 1e-196 rsiX
MEGKGOFH_02337 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MEGKGOFH_02338 3.3e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEGKGOFH_02339 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEGKGOFH_02340 4.7e-41 fer C Ferredoxin
MEGKGOFH_02341 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
MEGKGOFH_02342 3.5e-285 recQ 3.6.4.12 L DNA helicase
MEGKGOFH_02343 3.1e-99 ypbD S metal-dependent membrane protease
MEGKGOFH_02344 1.2e-73 ypbE M Lysin motif
MEGKGOFH_02345 2.8e-81 ypbF S Protein of unknown function (DUF2663)
MEGKGOFH_02346 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
MEGKGOFH_02347 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MEGKGOFH_02348 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MEGKGOFH_02349 2.1e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MEGKGOFH_02350 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
MEGKGOFH_02351 1.4e-89 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MEGKGOFH_02352 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MEGKGOFH_02353 1e-111 ypfA M Flagellar protein YcgR
MEGKGOFH_02354 1.8e-23 S Family of unknown function (DUF5359)
MEGKGOFH_02355 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MEGKGOFH_02356 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MEGKGOFH_02357 1.1e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MEGKGOFH_02358 1e-07 S YpzI-like protein
MEGKGOFH_02359 1.5e-101 yphA
MEGKGOFH_02360 2.5e-161 seaA S YIEGIA protein
MEGKGOFH_02361 1.6e-28 ypzH
MEGKGOFH_02362 3.3e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MEGKGOFH_02363 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MEGKGOFH_02364 1.6e-18 yphE S Protein of unknown function (DUF2768)
MEGKGOFH_02365 5.4e-138 yphF
MEGKGOFH_02366 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MEGKGOFH_02367 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEGKGOFH_02368 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MEGKGOFH_02369 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MEGKGOFH_02370 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MEGKGOFH_02371 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MEGKGOFH_02372 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MEGKGOFH_02373 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MEGKGOFH_02374 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MEGKGOFH_02375 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MEGKGOFH_02376 2e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MEGKGOFH_02377 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MEGKGOFH_02378 1.2e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MEGKGOFH_02379 2.7e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MEGKGOFH_02380 8.1e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MEGKGOFH_02381 4.7e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MEGKGOFH_02382 5.2e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MEGKGOFH_02383 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MEGKGOFH_02384 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MEGKGOFH_02385 7.5e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MEGKGOFH_02386 4.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEGKGOFH_02387 5.9e-233 S COG0457 FOG TPR repeat
MEGKGOFH_02388 1.1e-98 ypiB S Belongs to the UPF0302 family
MEGKGOFH_02389 4.2e-77 ypiF S Protein of unknown function (DUF2487)
MEGKGOFH_02390 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MEGKGOFH_02391 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MEGKGOFH_02392 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MEGKGOFH_02393 9.9e-98 ypjA S membrane
MEGKGOFH_02394 6.1e-143 ypjB S sporulation protein
MEGKGOFH_02395 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MEGKGOFH_02396 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MEGKGOFH_02397 2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEGKGOFH_02398 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MEGKGOFH_02399 6.9e-130 bshB1 S proteins, LmbE homologs
MEGKGOFH_02400 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MEGKGOFH_02401 3.5e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MEGKGOFH_02402 4.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEGKGOFH_02403 1.6e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MEGKGOFH_02404 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MEGKGOFH_02405 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MEGKGOFH_02406 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MEGKGOFH_02407 1.9e-22 ypmA S Protein of unknown function (DUF4264)
MEGKGOFH_02408 2.2e-79 ypmB S protein conserved in bacteria
MEGKGOFH_02409 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MEGKGOFH_02410 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MEGKGOFH_02411 5.7e-129 dnaD L DNA replication protein DnaD
MEGKGOFH_02412 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MEGKGOFH_02413 4.7e-93 ypoC
MEGKGOFH_02414 4.6e-41 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MEGKGOFH_02415 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MEGKGOFH_02416 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MEGKGOFH_02417 5.7e-50 yviE
MEGKGOFH_02418 7.8e-155 flgL N Belongs to the bacterial flagellin family
MEGKGOFH_02419 1.2e-264 flgK N flagellar hook-associated protein
MEGKGOFH_02420 1.6e-77 flgN NOU FlgN protein
MEGKGOFH_02421 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
MEGKGOFH_02422 7e-74 yvyF S flagellar protein
MEGKGOFH_02423 1.2e-126 comFC S Phosphoribosyl transferase domain
MEGKGOFH_02424 1.1e-44 comFB S Late competence development protein ComFB
MEGKGOFH_02425 1.2e-263 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MEGKGOFH_02426 7.3e-155 degV S protein conserved in bacteria
MEGKGOFH_02427 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEGKGOFH_02428 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MEGKGOFH_02429 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MEGKGOFH_02430 6e-163 yvhJ K Transcriptional regulator
MEGKGOFH_02431 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MEGKGOFH_02432 7.8e-235 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MEGKGOFH_02433 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
MEGKGOFH_02434 1.2e-101 tuaF M protein involved in exopolysaccharide biosynthesis
MEGKGOFH_02436 3.7e-263 tuaE M Teichuronic acid biosynthesis protein
MEGKGOFH_02437 1.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MEGKGOFH_02438 1.2e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MEGKGOFH_02439 3.1e-128 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEGKGOFH_02440 2.2e-92 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEGKGOFH_02441 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MEGKGOFH_02442 5.1e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MEGKGOFH_02443 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MEGKGOFH_02444 6e-38
MEGKGOFH_02445 1.8e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MEGKGOFH_02446 1e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MEGKGOFH_02447 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MEGKGOFH_02448 1.1e-56
MEGKGOFH_02449 4.3e-130 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEGKGOFH_02450 6.1e-76 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MEGKGOFH_02451 7.5e-93 ggaA M Glycosyltransferase like family 2
MEGKGOFH_02452 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MEGKGOFH_02453 1.1e-11 2.7.8.12 M CDPglycerol
MEGKGOFH_02454 5.3e-50 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MEGKGOFH_02455 6.3e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MEGKGOFH_02456 2.3e-122 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MEGKGOFH_02457 1.6e-140 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MEGKGOFH_02458 1.1e-150 tagG GM Transport permease protein
MEGKGOFH_02459 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MEGKGOFH_02460 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
MEGKGOFH_02461 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MEGKGOFH_02462 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MEGKGOFH_02463 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MEGKGOFH_02464 3.5e-260
MEGKGOFH_02465 5.2e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEGKGOFH_02466 3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MEGKGOFH_02467 3.5e-266 gerBA EG Spore germination protein
MEGKGOFH_02468 2.7e-194 gerBB E Spore germination protein
MEGKGOFH_02469 7.6e-216 gerAC S Spore germination protein
MEGKGOFH_02470 5.4e-248 ywtG EGP Major facilitator Superfamily
MEGKGOFH_02471 1.1e-170 ywtF K Transcriptional regulator
MEGKGOFH_02472 2.9e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MEGKGOFH_02473 9.2e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MEGKGOFH_02474 3.6e-21 ywtC
MEGKGOFH_02475 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MEGKGOFH_02476 8.6e-70 pgsC S biosynthesis protein
MEGKGOFH_02477 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MEGKGOFH_02478 9.3e-178 rbsR K transcriptional
MEGKGOFH_02479 2.7e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEGKGOFH_02480 3.1e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MEGKGOFH_02481 5.6e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MEGKGOFH_02482 1.2e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
MEGKGOFH_02483 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MEGKGOFH_02484 1.2e-91 batE T Sh3 type 3 domain protein
MEGKGOFH_02485 3.6e-48 ywsA S Protein of unknown function (DUF3892)
MEGKGOFH_02486 7.4e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MEGKGOFH_02487 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MEGKGOFH_02488 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MEGKGOFH_02489 1.1e-169 alsR K LysR substrate binding domain
MEGKGOFH_02490 9.5e-242 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MEGKGOFH_02491 9.2e-124 ywrJ
MEGKGOFH_02492 6.4e-131 cotB
MEGKGOFH_02493 3e-209 cotH M Spore Coat
MEGKGOFH_02494 4.9e-10 rsgI S Anti-sigma factor N-terminus
MEGKGOFH_02495 1.9e-26 sspD S small acid-soluble spore protein
MEGKGOFH_02496 2.4e-104 ykrK S Domain of unknown function (DUF1836)
MEGKGOFH_02497 3.5e-155 htpX O Belongs to the peptidase M48B family
MEGKGOFH_02498 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
MEGKGOFH_02499 1.2e-10 ydfR S Protein of unknown function (DUF421)
MEGKGOFH_02500 1.4e-20 ykzE
MEGKGOFH_02501 2.5e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MEGKGOFH_02502 0.0 kinE 2.7.13.3 T Histidine kinase
MEGKGOFH_02503 1.7e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEGKGOFH_02505 8.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MEGKGOFH_02506 4.1e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MEGKGOFH_02507 1e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MEGKGOFH_02508 3.4e-230 mtnE 2.6.1.83 E Aminotransferase
MEGKGOFH_02509 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MEGKGOFH_02510 1.1e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MEGKGOFH_02511 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MEGKGOFH_02512 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MEGKGOFH_02513 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
MEGKGOFH_02514 6.4e-09 S Spo0E like sporulation regulatory protein
MEGKGOFH_02515 1.4e-64 eag
MEGKGOFH_02516 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MEGKGOFH_02517 1.3e-75 ykvE K transcriptional
MEGKGOFH_02518 2.5e-125 motB N Flagellar motor protein
MEGKGOFH_02519 1e-137 motA N flagellar motor
MEGKGOFH_02520 0.0 clpE O Belongs to the ClpA ClpB family
MEGKGOFH_02521 1.8e-179 ykvI S membrane
MEGKGOFH_02522 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MEGKGOFH_02523 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MEGKGOFH_02524 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MEGKGOFH_02525 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MEGKGOFH_02526 3.8e-60 ykvN K HxlR-like helix-turn-helix
MEGKGOFH_02527 5.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
MEGKGOFH_02528 7.1e-214 ykvP 3.5.1.28 M Glycosyl transferases group 1
MEGKGOFH_02529 3.5e-35 3.5.1.104 M LysM domain
MEGKGOFH_02530 6.9e-162 G Glycosyl hydrolases family 18
MEGKGOFH_02531 4.3e-42 ykvR S Protein of unknown function (DUF3219)
MEGKGOFH_02532 6e-25 ykvS S protein conserved in bacteria
MEGKGOFH_02533 2.8e-28
MEGKGOFH_02534 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
MEGKGOFH_02535 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEGKGOFH_02536 1.6e-88 stoA CO thiol-disulfide
MEGKGOFH_02537 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MEGKGOFH_02538 2.3e-09
MEGKGOFH_02539 2.5e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MEGKGOFH_02540 5.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
MEGKGOFH_02541 7.6e-128 glcT K antiterminator
MEGKGOFH_02542 9.9e-69 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MEGKGOFH_02543 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MEGKGOFH_02544 2.1e-39 ptsH G phosphocarrier protein HPr
MEGKGOFH_02545 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEGKGOFH_02546 7.2e-39 splA S Transcriptional regulator
MEGKGOFH_02547 6.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
MEGKGOFH_02548 5.4e-127 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEGKGOFH_02549 8.2e-258 mcpC NT chemotaxis protein
MEGKGOFH_02550 5.6e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MEGKGOFH_02551 2.3e-123 ykwD J protein with SCP PR1 domains
MEGKGOFH_02552 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MEGKGOFH_02553 0.0 pilS 2.7.13.3 T Histidine kinase
MEGKGOFH_02554 3.3e-222 patA 2.6.1.1 E Aminotransferase
MEGKGOFH_02555 2.2e-15
MEGKGOFH_02556 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
MEGKGOFH_02557 1.7e-84 ykyB S YkyB-like protein
MEGKGOFH_02558 9.9e-236 ykuC EGP Major facilitator Superfamily
MEGKGOFH_02559 1.8e-87 ykuD S protein conserved in bacteria
MEGKGOFH_02560 9.4e-166 ykuE S Metallophosphoesterase
MEGKGOFH_02561 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_02562 5.2e-234 ykuI T Diguanylate phosphodiesterase
MEGKGOFH_02563 3.9e-37 ykuJ S protein conserved in bacteria
MEGKGOFH_02564 4.4e-94 ykuK S Ribonuclease H-like
MEGKGOFH_02565 3.9e-27 ykzF S Antirepressor AbbA
MEGKGOFH_02566 1.6e-76 ykuL S CBS domain
MEGKGOFH_02567 3.5e-168 ccpC K Transcriptional regulator
MEGKGOFH_02568 3.7e-87 fld C Flavodoxin domain
MEGKGOFH_02569 1.8e-175 ykuO
MEGKGOFH_02570 3.9e-78 fld C Flavodoxin
MEGKGOFH_02571 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MEGKGOFH_02572 2.6e-79 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MEGKGOFH_02573 3.9e-93 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MEGKGOFH_02574 9e-37 ykuS S Belongs to the UPF0180 family
MEGKGOFH_02575 8.8e-142 ykuT M Mechanosensitive ion channel
MEGKGOFH_02576 3.9e-101 ykuU O Alkyl hydroperoxide reductase
MEGKGOFH_02577 6.3e-81 ykuV CO thiol-disulfide
MEGKGOFH_02578 5.8e-95 rok K Repressor of ComK
MEGKGOFH_02579 5.5e-30 yknT
MEGKGOFH_02580 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MEGKGOFH_02581 3.5e-91 M1-753 M FR47-like protein
MEGKGOFH_02582 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
MEGKGOFH_02583 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MEGKGOFH_02584 5.1e-16 yuaE S DinB superfamily
MEGKGOFH_02585 4.5e-55 yuaE S DinB superfamily
MEGKGOFH_02586 2.3e-107 yuaD
MEGKGOFH_02587 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
MEGKGOFH_02588 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MEGKGOFH_02589 1.4e-95 yuaC K Belongs to the GbsR family
MEGKGOFH_02590 2.2e-91 yuaB
MEGKGOFH_02591 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
MEGKGOFH_02592 7.9e-236 ktrB P Potassium
MEGKGOFH_02593 1e-38 yiaA S yiaA/B two helix domain
MEGKGOFH_02594 1.1e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEGKGOFH_02595 3.4e-275 yubD P Major Facilitator Superfamily
MEGKGOFH_02596 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MEGKGOFH_02598 2.7e-50 S YolD-like protein
MEGKGOFH_02600 3.7e-71 K acetyltransferase
MEGKGOFH_02601 6e-25 K Helix-turn-helix domain
MEGKGOFH_02604 3.7e-103 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MEGKGOFH_02605 2.3e-30 xhlB S SPP1 phage holin
MEGKGOFH_02606 1.9e-27 xhlA S Haemolysin XhlA
MEGKGOFH_02611 4e-228 S peptidoglycan catabolic process
MEGKGOFH_02612 3.8e-49
MEGKGOFH_02613 2.2e-139
MEGKGOFH_02614 8.4e-29 S Phage tail assembly chaperone protein, TAC
MEGKGOFH_02615 2.3e-09 chiB 3.2.1.14 GH18 G Belongs to the glycosyl hydrolase 18 family
MEGKGOFH_02616 8.7e-34 S Phage tail tube protein
MEGKGOFH_02617 7.7e-30 S Protein of unknown function (DUF3168)
MEGKGOFH_02618 3.4e-36 S Bacteriophage HK97-gp10, putative tail-component
MEGKGOFH_02619 8.2e-28 S Phage head-tail joining protein
MEGKGOFH_02620 1.1e-28 S Phage gp6-like head-tail connector protein
MEGKGOFH_02622 1e-54 gpG
MEGKGOFH_02623 7.1e-44 S Phage minor structural protein GP20
MEGKGOFH_02625 2.7e-81 S Phage Mu protein F like protein
MEGKGOFH_02626 4.8e-122 S Phage portal protein, SPP1 Gp6-like
MEGKGOFH_02628 9.8e-196 S Phage terminase large subunit
MEGKGOFH_02629 1.8e-45 L Terminase small subunit
MEGKGOFH_02631 1.2e-79 L Transposase
MEGKGOFH_02643 7.6e-103 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
MEGKGOFH_02644 2.4e-126 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
MEGKGOFH_02646 6.9e-26
MEGKGOFH_02649 7.1e-27 yqaO S Phage-like element PBSX protein XtrA
MEGKGOFH_02651 4e-54 S Protein of unknown function (DUF1064)
MEGKGOFH_02654 6.5e-138 xkdC L IstB-like ATP binding protein
MEGKGOFH_02655 3.9e-37 3.1.3.16 L DnaD domain protein
MEGKGOFH_02656 4.9e-135 recT L RecT family
MEGKGOFH_02657 7.7e-153 yqaJ L YqaJ-like viral recombinase domain
MEGKGOFH_02661 7.5e-87
MEGKGOFH_02662 2.3e-67 S DNA binding
MEGKGOFH_02663 5.8e-15 S Helix-turn-helix domain
MEGKGOFH_02664 7.2e-17 K Helix-turn-helix domain
MEGKGOFH_02665 3.3e-17 xre K Helix-turn-helix XRE-family like proteins
MEGKGOFH_02667 8.8e-50
MEGKGOFH_02668 2.4e-27 S Protein of unknown function (DUF4064)
MEGKGOFH_02669 2.5e-49 xkdA E IrrE N-terminal-like domain
MEGKGOFH_02670 2.1e-26 L Belongs to the 'phage' integrase family
MEGKGOFH_02671 2.9e-131 L Belongs to the 'phage' integrase family
MEGKGOFH_02673 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MEGKGOFH_02674 1.7e-194 yubA S transporter activity
MEGKGOFH_02675 3.3e-183 ygjR S Oxidoreductase
MEGKGOFH_02676 9.1e-250 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MEGKGOFH_02677 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MEGKGOFH_02678 1.2e-274 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MEGKGOFH_02679 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
MEGKGOFH_02680 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MEGKGOFH_02682 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
MEGKGOFH_02685 4.1e-118 xkdC L Bacterial dnaA protein
MEGKGOFH_02686 5.9e-157 xkdB K sequence-specific DNA binding
MEGKGOFH_02688 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MEGKGOFH_02689 7.3e-109 xkdA E IrrE N-terminal-like domain
MEGKGOFH_02690 4.4e-160 ydbD P Catalase
MEGKGOFH_02691 7e-62 yjqB S Pfam:DUF867
MEGKGOFH_02692 6.1e-61 yjqA S Bacterial PH domain
MEGKGOFH_02693 2.7e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MEGKGOFH_02694 2.3e-30 S YCII-related domain
MEGKGOFH_02696 1e-212 S response regulator aspartate phosphatase
MEGKGOFH_02697 4.7e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MEGKGOFH_02698 1.5e-40 yjoA S DinB family
MEGKGOFH_02699 1.3e-29 yjoA S DinB family
MEGKGOFH_02700 2.2e-129 MA20_18170 S membrane transporter protein
MEGKGOFH_02701 1e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MEGKGOFH_02702 3.8e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MEGKGOFH_02703 2.3e-184 exuR K transcriptional
MEGKGOFH_02704 1.6e-225 exuT G Sugar (and other) transporter
MEGKGOFH_02705 2.2e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGKGOFH_02706 1.4e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MEGKGOFH_02707 1.8e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MEGKGOFH_02708 2.8e-193 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MEGKGOFH_02709 1.4e-248 yjmB G symporter YjmB
MEGKGOFH_02710 4.6e-282 uxaC 5.3.1.12 G glucuronate isomerase
MEGKGOFH_02711 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
MEGKGOFH_02712 7.1e-66 yjlC S Protein of unknown function (DUF1641)
MEGKGOFH_02713 3.4e-91 yjlB S Cupin domain
MEGKGOFH_02714 2.3e-176 yjlA EG Putative multidrug resistance efflux transporter
MEGKGOFH_02715 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MEGKGOFH_02716 1.9e-122 ybbM S transport system, permease component
MEGKGOFH_02717 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MEGKGOFH_02718 8.2e-30
MEGKGOFH_02719 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MEGKGOFH_02720 3e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MEGKGOFH_02722 1.3e-116 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MEGKGOFH_02725 1.6e-94 yjgD S Protein of unknown function (DUF1641)
MEGKGOFH_02726 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MEGKGOFH_02727 2e-103 yjgB S Domain of unknown function (DUF4309)
MEGKGOFH_02728 6e-45 T PhoQ Sensor
MEGKGOFH_02729 1.2e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
MEGKGOFH_02730 8.9e-20 yjfB S Putative motility protein
MEGKGOFH_02731 4.6e-82 S Protein of unknown function (DUF2690)
MEGKGOFH_02732 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
MEGKGOFH_02734 5.6e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MEGKGOFH_02735 1e-51 yjdJ S Domain of unknown function (DUF4306)
MEGKGOFH_02736 4.2e-29 S Domain of unknown function (DUF4177)
MEGKGOFH_02737 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEGKGOFH_02739 3.1e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MEGKGOFH_02740 1.8e-38 yjdF S Protein of unknown function (DUF2992)
MEGKGOFH_02741 2.4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
MEGKGOFH_02742 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MEGKGOFH_02743 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MEGKGOFH_02745 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
MEGKGOFH_02746 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
MEGKGOFH_02747 4.2e-92 yqaS L DNA packaging
MEGKGOFH_02748 4.1e-49 S YjcQ protein
MEGKGOFH_02749 2.9e-71 yjcP
MEGKGOFH_02750 3.6e-79 L Transposase
MEGKGOFH_02753 2.6e-44 yjcN
MEGKGOFH_02754 4.6e-190 S Putative amidase domain
MEGKGOFH_02758 1.5e-144 yjcL S Protein of unknown function (DUF819)
MEGKGOFH_02759 8.4e-46 yjcL S Protein of unknown function (DUF819)
MEGKGOFH_02760 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
MEGKGOFH_02761 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MEGKGOFH_02762 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MEGKGOFH_02763 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
MEGKGOFH_02764 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MEGKGOFH_02765 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEGKGOFH_02766 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEGKGOFH_02767 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEGKGOFH_02768 1.8e-31 yaaB S Domain of unknown function (DUF370)
MEGKGOFH_02769 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEGKGOFH_02770 2.4e-33 yaaA S S4 domain
MEGKGOFH_02771 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEGKGOFH_02772 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEGKGOFH_02773 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEGKGOFH_02774 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEGKGOFH_02775 6.5e-108 jag S single-stranded nucleic acid binding R3H
MEGKGOFH_02776 2.4e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEGKGOFH_02777 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEGKGOFH_02778 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MEGKGOFH_02779 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MEGKGOFH_02780 9.6e-74 S Bacterial PH domain
MEGKGOFH_02781 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MEGKGOFH_02782 1.1e-117 spo0J K Belongs to the ParB family
MEGKGOFH_02783 1.6e-111 yyaC S Sporulation protein YyaC
MEGKGOFH_02784 8.1e-177 yyaD S Membrane
MEGKGOFH_02785 2.3e-33 yyzM S protein conserved in bacteria
MEGKGOFH_02786 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEGKGOFH_02787 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEGKGOFH_02788 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MEGKGOFH_02789 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEGKGOFH_02790 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEGKGOFH_02791 4.9e-142 xth 3.1.11.2 L exodeoxyribonuclease III
MEGKGOFH_02792 3.6e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MEGKGOFH_02793 2.2e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEGKGOFH_02794 9.6e-95 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MEGKGOFH_02795 6.1e-244 EGP Major facilitator superfamily
MEGKGOFH_02796 8e-168 yyaK S CAAX protease self-immunity
MEGKGOFH_02797 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MEGKGOFH_02798 4.4e-161 yyaM EG EamA-like transporter family
MEGKGOFH_02799 1.5e-60 yyaN K MerR HTH family regulatory protein
MEGKGOFH_02800 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
MEGKGOFH_02801 2.8e-244 tetL EGP Major facilitator Superfamily
MEGKGOFH_02802 2.6e-103 yyaP 1.5.1.3 H RibD C-terminal domain
MEGKGOFH_02803 1.3e-65 yyaQ S YjbR
MEGKGOFH_02804 4.2e-92 yyaR K Acetyltransferase (GNAT) domain
MEGKGOFH_02805 2.5e-96 yyaS S Membrane
MEGKGOFH_02806 7.2e-69 yjcF S Acetyltransferase (GNAT) domain
MEGKGOFH_02807 5.6e-77 yybA 2.3.1.57 K transcriptional
MEGKGOFH_02808 3.6e-125 S Metallo-beta-lactamase superfamily
MEGKGOFH_02809 8.9e-73 yybC
MEGKGOFH_02810 1.7e-78 yjcF S Acetyltransferase (GNAT) domain
MEGKGOFH_02811 6.9e-164 yybE K Transcriptional regulator
MEGKGOFH_02812 2e-217 ynfM EGP Major facilitator Superfamily
MEGKGOFH_02813 3.7e-122 yybG S Pentapeptide repeat-containing protein
MEGKGOFH_02814 2.3e-66 yybH S SnoaL-like domain
MEGKGOFH_02815 2.5e-125
MEGKGOFH_02816 1.2e-96 K TipAS antibiotic-recognition domain
MEGKGOFH_02817 6.7e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MEGKGOFH_02819 7.3e-61
MEGKGOFH_02820 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MEGKGOFH_02821 6.8e-68 ydeP3 K Transcriptional regulator
MEGKGOFH_02822 3.9e-84 cotF M Spore coat protein
MEGKGOFH_02824 2.9e-160 yybS S membrane
MEGKGOFH_02825 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MEGKGOFH_02826 2.2e-73 rplI J binds to the 23S rRNA
MEGKGOFH_02827 1.5e-306 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEGKGOFH_02828 8.4e-221 yeaN P COG2807 Cyanate permease
MEGKGOFH_02829 1.9e-15 yycC K YycC-like protein
MEGKGOFH_02831 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MEGKGOFH_02833 2.6e-225 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MEGKGOFH_02834 1e-77 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEGKGOFH_02835 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEGKGOFH_02838 8.5e-87 yteJ S RDD family
MEGKGOFH_02839 1.9e-178 sppA OU signal peptide peptidase SppA
MEGKGOFH_02840 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEGKGOFH_02841 0.0 ytcJ S amidohydrolase
MEGKGOFH_02842 1.1e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MEGKGOFH_02843 2e-29 sspB S spore protein
MEGKGOFH_02844 1.3e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEGKGOFH_02845 1.7e-207 iscS2 2.8.1.7 E Cysteine desulfurase
MEGKGOFH_02846 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
MEGKGOFH_02847 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MEGKGOFH_02848 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MEGKGOFH_02849 3.4e-109 yttP K Transcriptional regulator
MEGKGOFH_02850 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MEGKGOFH_02851 7.2e-311 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MEGKGOFH_02852 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEGKGOFH_02854 5.4e-75 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEGKGOFH_02855 5.8e-116 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MEGKGOFH_02856 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MEGKGOFH_02857 1.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MEGKGOFH_02858 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MEGKGOFH_02859 5.6e-225 acuC BQ histone deacetylase
MEGKGOFH_02860 4e-125 motS N Flagellar motor protein
MEGKGOFH_02861 2.1e-146 motA N flagellar motor
MEGKGOFH_02862 1.7e-182 ccpA K catabolite control protein A
MEGKGOFH_02863 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MEGKGOFH_02864 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
MEGKGOFH_02865 6.6e-17 ytxH S COG4980 Gas vesicle protein
MEGKGOFH_02866 1.2e-15 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MEGKGOFH_02867 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MEGKGOFH_02868 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MEGKGOFH_02869 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEGKGOFH_02870 9.8e-149 ytpQ S Belongs to the UPF0354 family
MEGKGOFH_02871 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MEGKGOFH_02872 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MEGKGOFH_02873 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MEGKGOFH_02874 9.8e-52 ytzB S small secreted protein
MEGKGOFH_02875 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MEGKGOFH_02876 2.4e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MEGKGOFH_02877 2.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEGKGOFH_02878 2e-45 ytzH S YtzH-like protein
MEGKGOFH_02879 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
MEGKGOFH_02880 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MEGKGOFH_02881 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MEGKGOFH_02882 1.3e-165 ytlQ
MEGKGOFH_02883 5.6e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MEGKGOFH_02884 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MEGKGOFH_02885 2.7e-271 pepV 3.5.1.18 E Dipeptidase
MEGKGOFH_02886 2.1e-225 pbuO S permease
MEGKGOFH_02887 1.6e-200 ythQ U Bacterial ABC transporter protein EcsB
MEGKGOFH_02888 1.8e-130 ythP V ABC transporter
MEGKGOFH_02889 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MEGKGOFH_02890 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MEGKGOFH_02891 2.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEGKGOFH_02892 1.8e-231 ytfP S HI0933-like protein
MEGKGOFH_02893 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MEGKGOFH_02894 3.1e-26 yteV S Sporulation protein Cse60
MEGKGOFH_02895 4.5e-115 yteU S Integral membrane protein
MEGKGOFH_02896 6.6e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MEGKGOFH_02897 1.4e-25 yteS G transport
MEGKGOFH_02898 2e-36 yteS G transport
MEGKGOFH_02899 8.3e-136 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MEGKGOFH_02900 4.3e-122 yqfA S UPF0365 protein
MEGKGOFH_02901 1.7e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MEGKGOFH_02902 2.5e-61 yqeY S Yqey-like protein
MEGKGOFH_02903 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MEGKGOFH_02904 8.2e-158 yqeW P COG1283 Na phosphate symporter
MEGKGOFH_02905 6.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MEGKGOFH_02906 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEGKGOFH_02907 4.6e-174 prmA J Methylates ribosomal protein L11
MEGKGOFH_02908 9.4e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEGKGOFH_02909 0.0 dnaK O Heat shock 70 kDa protein
MEGKGOFH_02910 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEGKGOFH_02911 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEGKGOFH_02912 1.8e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
MEGKGOFH_02913 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEGKGOFH_02914 8e-52 yqxA S Protein of unknown function (DUF3679)
MEGKGOFH_02915 5.1e-37 spoIIP M stage II sporulation protein P
MEGKGOFH_02916 3.8e-154 spoIIP M stage II sporulation protein P
MEGKGOFH_02917 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MEGKGOFH_02918 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
MEGKGOFH_02919 4.1e-15 S YqzM-like protein
MEGKGOFH_02920 0.0 comEC S Competence protein ComEC
MEGKGOFH_02921 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MEGKGOFH_02922 7.3e-104 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MEGKGOFH_02923 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEGKGOFH_02924 1.4e-138 yqeM Q Methyltransferase
MEGKGOFH_02925 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEGKGOFH_02926 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MEGKGOFH_02927 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEGKGOFH_02928 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MEGKGOFH_02929 3.9e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MEGKGOFH_02930 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MEGKGOFH_02931 8.2e-60 yqeG S hydrolase of the HAD superfamily
MEGKGOFH_02933 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
MEGKGOFH_02934 7e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MEGKGOFH_02935 1e-105 yqeD S SNARE associated Golgi protein
MEGKGOFH_02936 6.5e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MEGKGOFH_02937 2.3e-133 yqeB
MEGKGOFH_02938 3.1e-74 nucB M Deoxyribonuclease NucA/NucB
MEGKGOFH_02939 4e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEGKGOFH_02940 1.8e-62 napB K helix_turn_helix multiple antibiotic resistance protein
MEGKGOFH_02941 3.7e-220 yfjF U Belongs to the major facilitator superfamily
MEGKGOFH_02942 6e-277 cisA2 L Recombinase
MEGKGOFH_02943 4.8e-191 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MEGKGOFH_02946 1.2e-64 S response regulator aspartate phosphatase
MEGKGOFH_02948 3.4e-28
MEGKGOFH_02949 1.7e-302 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MEGKGOFH_02950 7.8e-82 S SMI1-KNR4 cell-wall
MEGKGOFH_02951 3e-117 EGP Necrosis inducing protein (NPP1)
MEGKGOFH_02952 1e-100 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MEGKGOFH_02953 4.8e-27 S phage terminase, large subunit
MEGKGOFH_02954 1.4e-58 yqaS L DNA packaging
MEGKGOFH_02955 6.3e-23
MEGKGOFH_02957 3.7e-26 cotD S Inner spore coat protein D
MEGKGOFH_02958 8.2e-76 L Transposase
MEGKGOFH_02960 6.2e-31 yqaO S Phage-like element PBSX protein XtrA
MEGKGOFH_02961 5.9e-40 rusA L Endodeoxyribonuclease RusA
MEGKGOFH_02964 8.4e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
MEGKGOFH_02965 1.8e-90 K Transcriptional regulator PadR-like family
MEGKGOFH_02966 2e-97 adk 2.7.4.3 F adenylate kinase activity
MEGKGOFH_02967 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEGKGOFH_02968 3.3e-113 tetR3 K Transcriptional regulator
MEGKGOFH_02969 1.4e-216 mepA V Multidrug transporter MatE
MEGKGOFH_02970 7e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MEGKGOFH_02971 9.1e-127 ytrE V ABC transporter, ATP-binding protein
MEGKGOFH_02972 1.3e-147
MEGKGOFH_02973 2.1e-153 P ABC-2 family transporter protein
MEGKGOFH_02974 4.2e-161 ytrB P abc transporter atp-binding protein
MEGKGOFH_02975 5.1e-66 ytrA K GntR family transcriptional regulator
MEGKGOFH_02976 6.7e-41 ytzC S Protein of unknown function (DUF2524)
MEGKGOFH_02977 3.1e-189 yhcC S Fe-S oxidoreductase
MEGKGOFH_02978 1.2e-103 ytqB J Putative rRNA methylase
MEGKGOFH_02979 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MEGKGOFH_02980 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
MEGKGOFH_02981 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MEGKGOFH_02982 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MEGKGOFH_02983 0.0 asnB 6.3.5.4 E Asparagine synthase
MEGKGOFH_02984 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEGKGOFH_02985 2.6e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MEGKGOFH_02986 1.2e-38 ytmB S Protein of unknown function (DUF2584)
MEGKGOFH_02987 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MEGKGOFH_02988 2.8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MEGKGOFH_02989 1.4e-144 ytlC P ABC transporter
MEGKGOFH_02990 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MEGKGOFH_02991 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MEGKGOFH_02992 5.4e-63 ytkC S Bacteriophage holin family
MEGKGOFH_02993 2.1e-76 dps P Belongs to the Dps family
MEGKGOFH_02995 6.9e-72 ytkA S YtkA-like
MEGKGOFH_02996 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEGKGOFH_02997 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MEGKGOFH_02998 3.6e-41 rpmE2 J Ribosomal protein L31
MEGKGOFH_02999 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
MEGKGOFH_03000 1.1e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MEGKGOFH_03001 1.1e-24 S Domain of Unknown Function (DUF1540)
MEGKGOFH_03002 1.5e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MEGKGOFH_03003 3.6e-233 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MEGKGOFH_03004 2.1e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MEGKGOFH_03005 6.7e-170 troA P Belongs to the bacterial solute-binding protein 9 family
MEGKGOFH_03006 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MEGKGOFH_03007 2.3e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MEGKGOFH_03008 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MEGKGOFH_03009 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MEGKGOFH_03010 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MEGKGOFH_03011 7.4e-233 menF 5.4.4.2 HQ Isochorismate synthase
MEGKGOFH_03012 3e-24 menF 5.4.4.2 HQ Isochorismate synthase
MEGKGOFH_03013 4.4e-132 dksA T COG1734 DnaK suppressor protein
MEGKGOFH_03014 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
MEGKGOFH_03015 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MEGKGOFH_03016 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MEGKGOFH_03017 8.2e-232 ytcC M Glycosyltransferase Family 4
MEGKGOFH_03019 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
MEGKGOFH_03020 1.8e-217 cotSA M Glycosyl transferases group 1
MEGKGOFH_03022 2.2e-187 cotI S Spore coat protein
MEGKGOFH_03023 1.2e-74 tspO T membrane
MEGKGOFH_03024 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MEGKGOFH_03025 2.5e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MEGKGOFH_03026 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MEGKGOFH_03027 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MEGKGOFH_03028 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MEGKGOFH_03037 7.8e-08
MEGKGOFH_03038 1.3e-09
MEGKGOFH_03045 2e-08
MEGKGOFH_03050 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MEGKGOFH_03051 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MEGKGOFH_03052 2.1e-165 sodA 1.15.1.1 P Superoxide dismutase
MEGKGOFH_03053 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MEGKGOFH_03054 3.3e-167 yocS S -transporter
MEGKGOFH_03055 9.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MEGKGOFH_03056 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MEGKGOFH_03057 0.0 yojO P Von Willebrand factor
MEGKGOFH_03058 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
MEGKGOFH_03059 1.5e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MEGKGOFH_03060 3.9e-197 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MEGKGOFH_03061 3.4e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MEGKGOFH_03062 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEGKGOFH_03064 8.5e-97 norM V Multidrug efflux pump
MEGKGOFH_03065 2.2e-117 norM V Multidrug efflux pump
MEGKGOFH_03066 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MEGKGOFH_03067 2.1e-125 yojG S deacetylase
MEGKGOFH_03068 2.2e-60 yojF S Protein of unknown function (DUF1806)
MEGKGOFH_03069 1.5e-43
MEGKGOFH_03070 3.6e-100 rarD S -transporter
MEGKGOFH_03071 5.9e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
MEGKGOFH_03072 2e-09
MEGKGOFH_03073 8.5e-206 gntP EG COG2610 H gluconate symporter and related permeases
MEGKGOFH_03074 8e-64 yodA S tautomerase
MEGKGOFH_03075 4.4e-55 yodB K transcriptional
MEGKGOFH_03076 1.4e-107 yodC C nitroreductase
MEGKGOFH_03077 3.8e-113 mhqD S Carboxylesterase
MEGKGOFH_03078 2.2e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
MEGKGOFH_03079 6.2e-28 S Protein of unknown function (DUF3311)
MEGKGOFH_03080 4.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEGKGOFH_03081 7e-246 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MEGKGOFH_03082 6.3e-128 yodH Q Methyltransferase
MEGKGOFH_03083 5.2e-24 yodI
MEGKGOFH_03084 1.5e-115 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MEGKGOFH_03085 9.4e-13 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MEGKGOFH_03086 1.6e-88 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MEGKGOFH_03087 2.5e-25 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MEGKGOFH_03088 5.3e-09
MEGKGOFH_03089 3.6e-54 yodL S YodL-like
MEGKGOFH_03090 3.5e-106 yodM 3.6.1.27 I Acid phosphatase homologues
MEGKGOFH_03091 2.8e-24 yozD S YozD-like protein
MEGKGOFH_03093 1.6e-123 yodN
MEGKGOFH_03094 1.4e-36 yozE S Belongs to the UPF0346 family
MEGKGOFH_03095 2.9e-47 yokU S YokU-like protein, putative antitoxin
MEGKGOFH_03096 4.9e-54 kamA 5.4.3.2 E lysine 2,3-aminomutase
MEGKGOFH_03097 1.1e-42
MEGKGOFH_03099 6.8e-91 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEGKGOFH_03100 1.6e-09 K Cro/C1-type HTH DNA-binding domain
MEGKGOFH_03102 2.1e-29 S Macro domain
MEGKGOFH_03111 6.1e-162 S Calcineurin-like phosphoesterase
MEGKGOFH_03112 2.5e-30 sspB S spore protein
MEGKGOFH_03115 1.1e-39
MEGKGOFH_03117 7e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEGKGOFH_03118 5.2e-161 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEGKGOFH_03121 5.2e-15
MEGKGOFH_03122 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MEGKGOFH_03123 2e-82 yncE S Protein of unknown function (DUF2691)
MEGKGOFH_03124 2.2e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEGKGOFH_03125 6.7e-124 iolT EGP Major facilitator Superfamily
MEGKGOFH_03126 9.8e-35
MEGKGOFH_03127 7.6e-65
MEGKGOFH_03128 8.8e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MEGKGOFH_03129 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MEGKGOFH_03130 1.3e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MEGKGOFH_03131 7.6e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MEGKGOFH_03132 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MEGKGOFH_03133 1.6e-225 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MEGKGOFH_03134 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MEGKGOFH_03135 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MEGKGOFH_03136 3.8e-139 yvpB NU protein conserved in bacteria
MEGKGOFH_03137 1.5e-118 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MEGKGOFH_03138 5.6e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MEGKGOFH_03139 6.5e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MEGKGOFH_03140 2.4e-162 yvoD P COG0370 Fe2 transport system protein B
MEGKGOFH_03141 8.3e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEGKGOFH_03142 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MEGKGOFH_03143 3.9e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MEGKGOFH_03144 2.7e-129 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MEGKGOFH_03145 3.6e-134 yvoA K transcriptional
MEGKGOFH_03146 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MEGKGOFH_03147 2.8e-49 adcR K helix_turn_helix multiple antibiotic resistance protein
MEGKGOFH_03148 4.1e-231 cypX 1.14.15.13 C Cytochrome P450
MEGKGOFH_03149 4.7e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MEGKGOFH_03150 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
MEGKGOFH_03151 2.3e-202 yvmA EGP Major facilitator Superfamily
MEGKGOFH_03152 1.2e-50 yvlD S Membrane
MEGKGOFH_03153 2.6e-26 pspB KT PspC domain
MEGKGOFH_03154 7.5e-168 yvlB S Putative adhesin
MEGKGOFH_03155 8e-49 yvlA
MEGKGOFH_03156 6.7e-34 yvkN
MEGKGOFH_03157 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MEGKGOFH_03158 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEGKGOFH_03159 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEGKGOFH_03160 1.2e-30 csbA S protein conserved in bacteria
MEGKGOFH_03161 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MEGKGOFH_03162 7e-101 yvkB K Transcriptional regulator
MEGKGOFH_03163 1.3e-225 yvkA EGP Major facilitator Superfamily
MEGKGOFH_03164 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MEGKGOFH_03165 5.3e-56 swrA S Swarming motility protein
MEGKGOFH_03166 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MEGKGOFH_03167 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MEGKGOFH_03168 1.6e-123 ftsE D cell division ATP-binding protein FtsE
MEGKGOFH_03169 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
MEGKGOFH_03170 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MEGKGOFH_03171 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEGKGOFH_03172 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEGKGOFH_03173 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEGKGOFH_03174 2.8e-66
MEGKGOFH_03175 4.9e-09 fliT S bacterial-type flagellum organization
MEGKGOFH_03176 2.9e-69 fliS N flagellar protein FliS
MEGKGOFH_03177 5.9e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MEGKGOFH_03178 1.2e-55 flaG N flagellar protein FlaG
MEGKGOFH_03179 7.7e-80 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MEGKGOFH_03180 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MEGKGOFH_03181 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEGKGOFH_03182 4.1e-30 yazB K transcriptional
MEGKGOFH_03183 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MEGKGOFH_03184 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MEGKGOFH_03185 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MEGKGOFH_03186 1.3e-165 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MEGKGOFH_03187 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MEGKGOFH_03188 3.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MEGKGOFH_03189 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MEGKGOFH_03190 3.4e-152 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MEGKGOFH_03191 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MEGKGOFH_03192 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MEGKGOFH_03193 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEGKGOFH_03194 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MEGKGOFH_03195 4.7e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEGKGOFH_03196 3.7e-185 KLT serine threonine protein kinase
MEGKGOFH_03197 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MEGKGOFH_03198 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MEGKGOFH_03201 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MEGKGOFH_03202 1.1e-44 divIC D Septum formation initiator
MEGKGOFH_03203 1.2e-106 yabQ S spore cortex biosynthesis protein
MEGKGOFH_03204 1.5e-49 yabP S Sporulation protein YabP
MEGKGOFH_03205 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MEGKGOFH_03206 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MEGKGOFH_03207 2.1e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MEGKGOFH_03208 1.5e-92 spoVT K stage V sporulation protein
MEGKGOFH_03209 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEGKGOFH_03210 2.4e-39 yabK S Peptide ABC transporter permease
MEGKGOFH_03211 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEGKGOFH_03212 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MEGKGOFH_03213 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEGKGOFH_03214 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEGKGOFH_03215 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MEGKGOFH_03216 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MEGKGOFH_03217 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MEGKGOFH_03218 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEGKGOFH_03219 8.3e-27 sspF S DNA topological change
MEGKGOFH_03220 7.8e-39 veg S protein conserved in bacteria
MEGKGOFH_03221 1.8e-135 yabG S peptidase
MEGKGOFH_03222 2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEGKGOFH_03223 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MEGKGOFH_03224 2e-167 rpfB GH23 T protein conserved in bacteria
MEGKGOFH_03225 1.2e-143 tatD L hydrolase, TatD
MEGKGOFH_03226 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEGKGOFH_03227 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MEGKGOFH_03228 3.5e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEGKGOFH_03229 1.5e-49 yazA L endonuclease containing a URI domain
MEGKGOFH_03230 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
MEGKGOFH_03231 4.8e-31 yabA L Involved in initiation control of chromosome replication
MEGKGOFH_03232 6.1e-146 yaaT S stage 0 sporulation protein
MEGKGOFH_03233 1.1e-181 holB 2.7.7.7 L DNA polymerase III
MEGKGOFH_03234 1.5e-71 yaaR S protein conserved in bacteria
MEGKGOFH_03235 2.2e-54 yaaQ S protein conserved in bacteria
MEGKGOFH_03238 7.8e-41 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEGKGOFH_03239 1.1e-11 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEGKGOFH_03240 2.6e-31 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEGKGOFH_03241 8.1e-149 ypuA S Secreted protein
MEGKGOFH_03242 1.7e-96 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEGKGOFH_03243 6.2e-151 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEGKGOFH_03244 1.4e-273 spoVAF EG Stage V sporulation protein AF
MEGKGOFH_03245 1.4e-110 spoVAEA S stage V sporulation protein
MEGKGOFH_03246 2.2e-57 spoVAEB S stage V sporulation protein
MEGKGOFH_03247 9e-192 spoVAD I Stage V sporulation protein AD
MEGKGOFH_03248 1.5e-77 spoVAC S stage V sporulation protein AC
MEGKGOFH_03249 1e-67 spoVAB S Stage V sporulation protein AB
MEGKGOFH_03250 9.6e-112 spoVAA S Stage V sporulation protein AA
MEGKGOFH_03251 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEGKGOFH_03252 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MEGKGOFH_03253 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MEGKGOFH_03254 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MEGKGOFH_03255 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MEGKGOFH_03256 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MEGKGOFH_03257 5.7e-166 xerD L recombinase XerD
MEGKGOFH_03258 1.4e-36 S Protein of unknown function (DUF4227)
MEGKGOFH_03259 2.4e-80 fur P Belongs to the Fur family
MEGKGOFH_03260 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MEGKGOFH_03261 2.2e-31 yqkK
MEGKGOFH_03262 5.5e-242 mleA 1.1.1.38 C malic enzyme
MEGKGOFH_03263 3.1e-235 mleN C Na H antiporter
MEGKGOFH_03264 1.3e-262 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MEGKGOFH_03265 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
MEGKGOFH_03266 4.5e-58 ansR K Transcriptional regulator
MEGKGOFH_03267 4.3e-222 yqxK 3.6.4.12 L DNA helicase
MEGKGOFH_03268 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MEGKGOFH_03270 1.8e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MEGKGOFH_03271 3.1e-12 yqkE S Protein of unknown function (DUF3886)
MEGKGOFH_03272 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MEGKGOFH_03273 9.4e-39 yqkC S Protein of unknown function (DUF2552)
MEGKGOFH_03274 2.8e-54 yqkB S Belongs to the HesB IscA family
MEGKGOFH_03275 5.2e-195 yqkA K GrpB protein
MEGKGOFH_03276 2.5e-53 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MEGKGOFH_03277 3.6e-87 yqjY K acetyltransferase
MEGKGOFH_03278 7.5e-50 S YolD-like protein
MEGKGOFH_03279 1.6e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEGKGOFH_03281 8e-190 yqjV G Major Facilitator Superfamily
MEGKGOFH_03283 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEGKGOFH_03284 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
MEGKGOFH_03285 1.6e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MEGKGOFH_03286 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGKGOFH_03287 1.8e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MEGKGOFH_03288 1.4e-142 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEGKGOFH_03289 0.0 rocB E arginine degradation protein
MEGKGOFH_03290 3.2e-150 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MEGKGOFH_03291 1.7e-23 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MEGKGOFH_03292 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MEGKGOFH_03293 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MEGKGOFH_03294 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEGKGOFH_03295 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEGKGOFH_03296 2e-227 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEGKGOFH_03297 3e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MEGKGOFH_03298 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEGKGOFH_03299 2.4e-56 yusD S SCP-2 sterol transfer family
MEGKGOFH_03300 1.2e-54 traF CO Thioredoxin
MEGKGOFH_03301 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MEGKGOFH_03302 1.1e-39 yusG S Protein of unknown function (DUF2553)
MEGKGOFH_03303 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MEGKGOFH_03304 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MEGKGOFH_03305 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MEGKGOFH_03306 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
MEGKGOFH_03307 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MEGKGOFH_03308 4.7e-09 S YuzL-like protein
MEGKGOFH_03309 6.4e-165 fadM E Proline dehydrogenase
MEGKGOFH_03310 5.1e-40
MEGKGOFH_03311 5.4e-53 yusN M Coat F domain
MEGKGOFH_03312 6.6e-73 yusO K Iron dependent repressor, N-terminal DNA binding domain
MEGKGOFH_03313 3.2e-292 yusP P Major facilitator superfamily
MEGKGOFH_03314 2.7e-64 yusQ S Tautomerase enzyme
MEGKGOFH_03315 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGKGOFH_03316 5.7e-158 yusT K LysR substrate binding domain
MEGKGOFH_03317 3.8e-47 yusU S Protein of unknown function (DUF2573)
MEGKGOFH_03318 1e-153 yusV 3.6.3.34 HP ABC transporter
MEGKGOFH_03319 2.5e-66 S YusW-like protein
MEGKGOFH_03320 4.6e-300 pepF2 E COG1164 Oligoendopeptidase F
MEGKGOFH_03321 6.4e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGKGOFH_03322 1.2e-79 dps P Ferritin-like domain
MEGKGOFH_03323 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MEGKGOFH_03324 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_03325 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
MEGKGOFH_03326 4.3e-158 yuxN K Transcriptional regulator
MEGKGOFH_03327 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MEGKGOFH_03328 2.3e-24 S Protein of unknown function (DUF3970)
MEGKGOFH_03329 1.4e-246 gerAA EG Spore germination protein
MEGKGOFH_03330 1.3e-196 gerAB E Spore germination protein
MEGKGOFH_03331 1.3e-180 gerAC S Spore germination B3/ GerAC like, C-terminal
MEGKGOFH_03332 3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEGKGOFH_03333 1.6e-186 vraS 2.7.13.3 T Histidine kinase
MEGKGOFH_03334 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MEGKGOFH_03335 2.3e-127 liaG S Putative adhesin
MEGKGOFH_03336 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MEGKGOFH_03337 5.6e-62 liaI S membrane
MEGKGOFH_03338 1.4e-226 yvqJ EGP Major facilitator Superfamily
MEGKGOFH_03339 1.9e-101 yvqK 2.5.1.17 S Adenosyltransferase
MEGKGOFH_03340 2.5e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MEGKGOFH_03341 2.3e-182 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEGKGOFH_03342 4.2e-49 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MEGKGOFH_03343 5e-84 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MEGKGOFH_03344 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MEGKGOFH_03345 1.3e-82 yqxM
MEGKGOFH_03346 7.3e-54 yqzG S Protein of unknown function (DUF3889)
MEGKGOFH_03347 5.2e-26 yqzE S YqzE-like protein
MEGKGOFH_03348 8.8e-44 S ComG operon protein 7
MEGKGOFH_03349 4.1e-46 comGF U Putative Competence protein ComGF
MEGKGOFH_03350 2.2e-57 comGE
MEGKGOFH_03351 3.3e-54 gspH NU protein transport across the cell outer membrane
MEGKGOFH_03352 6.8e-47 comGC U Required for transformation and DNA binding
MEGKGOFH_03353 6.6e-174 comGB NU COG1459 Type II secretory pathway, component PulF
MEGKGOFH_03354 1.1e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MEGKGOFH_03357 7.2e-175 corA P Mg2 transporter protein
MEGKGOFH_03358 9.8e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MEGKGOFH_03359 2.3e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MEGKGOFH_03361 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
MEGKGOFH_03362 5.3e-37 yqgY S Protein of unknown function (DUF2626)
MEGKGOFH_03363 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MEGKGOFH_03364 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MEGKGOFH_03365 6.9e-50 yqgV S Thiamine-binding protein
MEGKGOFH_03366 2.7e-199 yqgU
MEGKGOFH_03367 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MEGKGOFH_03368 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MEGKGOFH_03369 5.2e-181 glcK 2.7.1.2 G Glucokinase
MEGKGOFH_03370 4.3e-33 yqgQ S Protein conserved in bacteria
MEGKGOFH_03371 8.9e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MEGKGOFH_03372 2.5e-09 yqgO
MEGKGOFH_03373 2.5e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MEGKGOFH_03374 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MEGKGOFH_03375 2e-197 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MEGKGOFH_03377 9.2e-51 yqzD
MEGKGOFH_03378 7.3e-72 yqzC S YceG-like family
MEGKGOFH_03379 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEGKGOFH_03380 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEGKGOFH_03381 2.2e-157 pstA P Phosphate transport system permease
MEGKGOFH_03382 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MEGKGOFH_03383 6.7e-142 pstS P Phosphate
MEGKGOFH_03384 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MEGKGOFH_03385 2.5e-231 yqgE EGP Major facilitator superfamily
MEGKGOFH_03386 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MEGKGOFH_03387 4e-73 yqgC S protein conserved in bacteria
MEGKGOFH_03388 3.9e-131 yqgB S Protein of unknown function (DUF1189)
MEGKGOFH_03389 1.5e-46 yqfZ M LysM domain
MEGKGOFH_03390 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MEGKGOFH_03391 2.1e-61 yqfX S membrane
MEGKGOFH_03392 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MEGKGOFH_03393 1.9e-77 zur P Belongs to the Fur family
MEGKGOFH_03394 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MEGKGOFH_03395 2.1e-36 yqfT S Protein of unknown function (DUF2624)
MEGKGOFH_03396 6.5e-159 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MEGKGOFH_03397 4.7e-135 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MEGKGOFH_03398 3e-29 ypeQ S Zinc-finger
MEGKGOFH_03399 8.1e-31 S Protein of unknown function (DUF2564)
MEGKGOFH_03400 3.8e-16 degR
MEGKGOFH_03401 7.9e-31 cspD K Cold-shock protein
MEGKGOFH_03402 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MEGKGOFH_03404 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MEGKGOFH_03405 8.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MEGKGOFH_03406 5.4e-107 ypgQ S phosphohydrolase
MEGKGOFH_03407 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
MEGKGOFH_03408 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MEGKGOFH_03409 1.7e-75 yphP S Belongs to the UPF0403 family
MEGKGOFH_03410 3.5e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MEGKGOFH_03411 8.6e-113 ypjP S YpjP-like protein
MEGKGOFH_03412 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MEGKGOFH_03413 7.6e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEGKGOFH_03414 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEGKGOFH_03415 1.2e-109 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MEGKGOFH_03416 4.2e-110 hlyIII S protein, Hemolysin III
MEGKGOFH_03417 6.1e-185 pspF K Transcriptional regulator
MEGKGOFH_03418 4.3e-192 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MEGKGOFH_03419 3.1e-40 ypmP S Protein of unknown function (DUF2535)
MEGKGOFH_03420 7.1e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MEGKGOFH_03421 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
MEGKGOFH_03422 3.5e-49 ypmS S protein conserved in bacteria
MEGKGOFH_03423 5.5e-29 ypmT S Uncharacterized ympT
MEGKGOFH_03424 1.2e-173 mepA V MATE efflux family protein
MEGKGOFH_03425 1.6e-70 ypoP K transcriptional
MEGKGOFH_03426 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEGKGOFH_03427 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MEGKGOFH_03428 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
MEGKGOFH_03429 5.2e-212 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MEGKGOFH_03430 2.4e-186 cgeB S Spore maturation protein
MEGKGOFH_03431 1.2e-65 cgeA
MEGKGOFH_03432 5.9e-38 cgeC
MEGKGOFH_03433 8e-254 cgeD M maturation of the outermost layer of the spore
MEGKGOFH_03434 5.4e-144 yiiD K acetyltransferase
MEGKGOFH_03436 2.3e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEGKGOFH_03437 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MEGKGOFH_03438 2.3e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MEGKGOFH_03439 2.1e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
MEGKGOFH_03440 1.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MEGKGOFH_03441 4.7e-199 kamA 5.4.3.2 E lysine 2,3-aminomutase
MEGKGOFH_03442 1.4e-95 S Recombinase
MEGKGOFH_03443 3.5e-170 S Recombinase
MEGKGOFH_03445 2.1e-291 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MEGKGOFH_03446 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MEGKGOFH_03447 0.0 esaA S type VII secretion protein EsaA
MEGKGOFH_03448 3.3e-37 yueC S Family of unknown function (DUF5383)
MEGKGOFH_03449 6.4e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_03450 1.4e-95 yueE S phosphohydrolase
MEGKGOFH_03451 2.9e-24 S Protein of unknown function (DUF2642)
MEGKGOFH_03452 3.6e-13 S Protein of unknown function (DUF2283)
MEGKGOFH_03453 3.2e-190 yueF S transporter activity
MEGKGOFH_03454 2.1e-32 yueG S Spore germination protein gerPA/gerPF
MEGKGOFH_03455 7.4e-39 yueH S YueH-like protein
MEGKGOFH_03456 7.9e-67 yueI S Protein of unknown function (DUF1694)
MEGKGOFH_03457 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
MEGKGOFH_03458 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEGKGOFH_03459 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MEGKGOFH_03460 1.1e-22 yuzC
MEGKGOFH_03462 2.9e-139 comQ H Belongs to the FPP GGPP synthase family
MEGKGOFH_03464 7.1e-269 comP 2.7.13.3 T Histidine kinase
MEGKGOFH_03465 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MEGKGOFH_03466 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
MEGKGOFH_03467 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MEGKGOFH_03468 8.2e-15 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MEGKGOFH_03469 2.4e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MEGKGOFH_03470 1.6e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MEGKGOFH_03471 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MEGKGOFH_03472 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MEGKGOFH_03473 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MEGKGOFH_03474 3.2e-14
MEGKGOFH_03475 1.3e-233 maeN C COG3493 Na citrate symporter
MEGKGOFH_03476 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
MEGKGOFH_03477 1.4e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
MEGKGOFH_03478 1.3e-271 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MEGKGOFH_03479 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MEGKGOFH_03480 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MEGKGOFH_03481 2.4e-147 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MEGKGOFH_03482 3.4e-177 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEGKGOFH_03483 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEGKGOFH_03484 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MEGKGOFH_03485 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEGKGOFH_03486 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEGKGOFH_03487 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEGKGOFH_03488 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEGKGOFH_03489 4e-181 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MEGKGOFH_03490 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MEGKGOFH_03491 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEGKGOFH_03492 3e-105 rplD J Forms part of the polypeptide exit tunnel
MEGKGOFH_03493 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEGKGOFH_03494 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEGKGOFH_03495 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEGKGOFH_03496 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEGKGOFH_03497 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEGKGOFH_03498 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEGKGOFH_03499 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MEGKGOFH_03500 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEGKGOFH_03501 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEGKGOFH_03502 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEGKGOFH_03503 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEGKGOFH_03504 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEGKGOFH_03505 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEGKGOFH_03506 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEGKGOFH_03507 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEGKGOFH_03508 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEGKGOFH_03509 1.9e-23 rpmD J Ribosomal protein L30
MEGKGOFH_03510 1.8e-72 rplO J binds to the 23S rRNA
MEGKGOFH_03511 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEGKGOFH_03512 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEGKGOFH_03513 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MEGKGOFH_03514 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEGKGOFH_03515 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MEGKGOFH_03516 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEGKGOFH_03517 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEGKGOFH_03518 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEGKGOFH_03519 3.6e-58 rplQ J Ribosomal protein L17
MEGKGOFH_03520 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEGKGOFH_03521 6.3e-151 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEGKGOFH_03522 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEGKGOFH_03523 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEGKGOFH_03524 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEGKGOFH_03525 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MEGKGOFH_03526 5.3e-144 ybaJ Q Methyltransferase domain
MEGKGOFH_03527 9.7e-66 ybaK S Protein of unknown function (DUF2521)
MEGKGOFH_03528 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MEGKGOFH_03529 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MEGKGOFH_03530 7e-20 gerD
MEGKGOFH_03531 1.2e-21 gerD
MEGKGOFH_03532 4.1e-15 gerD
MEGKGOFH_03533 7.5e-116 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MEGKGOFH_03534 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
MEGKGOFH_03536 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
MEGKGOFH_03537 2e-07
MEGKGOFH_03538 1e-38 ypbS S Protein of unknown function (DUF2533)
MEGKGOFH_03539 7.8e-20 ypbR S Dynamin family
MEGKGOFH_03540 0.0 ypbR S Dynamin family
MEGKGOFH_03541 5.1e-87 ypbQ S protein conserved in bacteria
MEGKGOFH_03542 1.5e-205 bcsA Q Naringenin-chalcone synthase
MEGKGOFH_03543 7.8e-228 pbuX F xanthine
MEGKGOFH_03544 4.4e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEGKGOFH_03545 5.2e-256 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MEGKGOFH_03546 2.5e-23 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MEGKGOFH_03547 6.6e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MEGKGOFH_03548 2.7e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MEGKGOFH_03549 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MEGKGOFH_03550 7.4e-186 ptxS K transcriptional
MEGKGOFH_03551 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MEGKGOFH_03552 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEGKGOFH_03553 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MEGKGOFH_03555 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MEGKGOFH_03556 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MEGKGOFH_03557 5.7e-96 ypsA S Belongs to the UPF0398 family
MEGKGOFH_03558 5.1e-237 yprB L RNase_H superfamily
MEGKGOFH_03559 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MEGKGOFH_03560 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MEGKGOFH_03561 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
MEGKGOFH_03562 1.2e-48 yppG S YppG-like protein
MEGKGOFH_03564 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
MEGKGOFH_03566 1.6e-185 yppC S Protein of unknown function (DUF2515)
MEGKGOFH_03567 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEGKGOFH_03568 1.4e-30 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEGKGOFH_03569 2.9e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MEGKGOFH_03570 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEGKGOFH_03571 1.7e-78 argR K Regulates arginine biosynthesis genes
MEGKGOFH_03572 0.0 recN L May be involved in recombinational repair of damaged DNA
MEGKGOFH_03573 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
MEGKGOFH_03574 4.6e-118 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MEGKGOFH_03576 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MEGKGOFH_03577 5.9e-27
MEGKGOFH_03578 2.7e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MEGKGOFH_03579 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MEGKGOFH_03580 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
MEGKGOFH_03581 6.8e-156 hbdA 1.1.1.157 I Dehydrogenase
MEGKGOFH_03582 1.8e-212 mmgC I acyl-CoA dehydrogenase
MEGKGOFH_03583 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MEGKGOFH_03584 1.8e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MEGKGOFH_03585 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MEGKGOFH_03586 4e-34 yqzF S Protein of unknown function (DUF2627)
MEGKGOFH_03587 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MEGKGOFH_03588 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MEGKGOFH_03589 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MEGKGOFH_03590 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
MEGKGOFH_03591 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MEGKGOFH_03592 1.2e-185 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MEGKGOFH_03593 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MEGKGOFH_03594 1.3e-224 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEGKGOFH_03595 3.7e-151 bmrR K helix_turn_helix, mercury resistance
MEGKGOFH_03596 7.9e-208 norA EGP Major facilitator Superfamily
MEGKGOFH_03597 1.1e-89 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MEGKGOFH_03598 3.4e-62 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MEGKGOFH_03599 9.3e-77 yqiW S Belongs to the UPF0403 family
MEGKGOFH_03600 1.3e-38 mcpA NT chemotaxis protein
MEGKGOFH_03601 8.5e-295 mcpA NT chemotaxis protein
MEGKGOFH_03602 4.5e-219 mcpA NT chemotaxis protein
MEGKGOFH_03603 1.3e-223 mcpA NT chemotaxis protein
MEGKGOFH_03604 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MEGKGOFH_03605 2.1e-72 yugU S Uncharacterised protein family UPF0047
MEGKGOFH_03606 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MEGKGOFH_03607 1.4e-234 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MEGKGOFH_03608 9.2e-116 yugP S Zn-dependent protease
MEGKGOFH_03609 3.9e-38
MEGKGOFH_03610 5.4e-53 mstX S Membrane-integrating protein Mistic
MEGKGOFH_03611 8.2e-182 yugO P COG1226 Kef-type K transport systems
MEGKGOFH_03612 2.8e-72 yugN S YugN-like family
MEGKGOFH_03614 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
MEGKGOFH_03615 2.8e-229 yugK C Dehydrogenase
MEGKGOFH_03616 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MEGKGOFH_03617 1.1e-34 yuzA S Domain of unknown function (DUF378)
MEGKGOFH_03618 1.4e-38 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MEGKGOFH_03619 2.1e-199 yugH 2.6.1.1 E Aminotransferase
MEGKGOFH_03620 1.6e-85 alaR K Transcriptional regulator
MEGKGOFH_03621 4.9e-156 yugF I Hydrolase
MEGKGOFH_03622 4.6e-39 yugE S Domain of unknown function (DUF1871)
MEGKGOFH_03623 1.6e-224 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MEGKGOFH_03624 4.6e-233 T PhoQ Sensor
MEGKGOFH_03625 4.1e-68 kapB G Kinase associated protein B
MEGKGOFH_03626 4.2e-115 kapD L the KinA pathway to sporulation
MEGKGOFH_03628 3e-182 yuxJ EGP Major facilitator Superfamily
MEGKGOFH_03629 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MEGKGOFH_03630 1.8e-74 yuxK S protein conserved in bacteria
MEGKGOFH_03631 6.3e-78 yufK S Family of unknown function (DUF5366)
MEGKGOFH_03632 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MEGKGOFH_03633 3e-158 ytdP K Transcriptional regulator
MEGKGOFH_03634 1.7e-243 ytdP K Transcriptional regulator
MEGKGOFH_03635 1.4e-286 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MEGKGOFH_03636 8.4e-143 ytcP G COG0395 ABC-type sugar transport system, permease component
MEGKGOFH_03637 6.2e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MEGKGOFH_03638 5.7e-222 bioI 1.14.14.46 C Cytochrome P450
MEGKGOFH_03639 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MEGKGOFH_03640 1.3e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MEGKGOFH_03641 2.2e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MEGKGOFH_03642 1.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MEGKGOFH_03643 3.1e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MEGKGOFH_03644 5.4e-172 ytaP S Acetyl xylan esterase (AXE1)
MEGKGOFH_03645 1.5e-189 msmR K Transcriptional regulator
MEGKGOFH_03646 2.4e-242 msmE G Bacterial extracellular solute-binding protein
MEGKGOFH_03647 6.2e-168 amyD P ABC transporter
MEGKGOFH_03648 3.7e-143 amyC P ABC transporter (permease)
MEGKGOFH_03649 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MEGKGOFH_03650 2.1e-51 ytwF P Sulfurtransferase
MEGKGOFH_03651 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEGKGOFH_03652 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MEGKGOFH_03653 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MEGKGOFH_03654 6.6e-210 yttB EGP Major facilitator Superfamily
MEGKGOFH_03655 1.7e-25 yttA 2.7.13.3 S Pfam Transposase IS66
MEGKGOFH_03656 0.0 bceB V ABC transporter (permease)
MEGKGOFH_03657 1.1e-138 bceA V ABC transporter, ATP-binding protein
MEGKGOFH_03658 1.8e-184 T PhoQ Sensor
MEGKGOFH_03659 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_03660 1.2e-109 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MEGKGOFH_03661 0.0 vpr O Belongs to the peptidase S8 family
MEGKGOFH_03662 7.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MEGKGOFH_03663 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MEGKGOFH_03664 2.8e-163 rodA D Belongs to the SEDS family
MEGKGOFH_03665 9.1e-27 rodA D Belongs to the SEDS family
MEGKGOFH_03666 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
MEGKGOFH_03667 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MEGKGOFH_03668 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MEGKGOFH_03669 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MEGKGOFH_03670 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MEGKGOFH_03671 1e-35 ywzA S membrane
MEGKGOFH_03672 1.8e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MEGKGOFH_03673 8.4e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEGKGOFH_03674 9.5e-60 gtcA S GtrA-like protein
MEGKGOFH_03675 1.1e-121 ywcC K transcriptional regulator
MEGKGOFH_03677 8.3e-48 ywcB S Protein of unknown function, DUF485
MEGKGOFH_03678 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MEGKGOFH_03679 9.3e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MEGKGOFH_03680 1.8e-221 ywbN P Dyp-type peroxidase family protein
MEGKGOFH_03681 3.9e-183 ycdO P periplasmic lipoprotein involved in iron transport
MEGKGOFH_03682 4.5e-253 P COG0672 High-affinity Fe2 Pb2 permease
MEGKGOFH_03683 9.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MEGKGOFH_03684 2.6e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MEGKGOFH_03685 4.3e-153 ywbI K Transcriptional regulator
MEGKGOFH_03686 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MEGKGOFH_03687 2.3e-111 ywbG M effector of murein hydrolase
MEGKGOFH_03688 2.2e-205 ywbF EGP Major facilitator Superfamily
MEGKGOFH_03689 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
MEGKGOFH_03690 1.4e-41 ywbD 2.1.1.191 J Methyltransferase
MEGKGOFH_03691 2.7e-169 ywbD 2.1.1.191 J Methyltransferase
MEGKGOFH_03692 4.4e-67 ywbC 4.4.1.5 E glyoxalase
MEGKGOFH_03693 1.1e-245 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEGKGOFH_03694 3.6e-236 epr 3.4.21.62 O Belongs to the peptidase S8 family
MEGKGOFH_03695 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
MEGKGOFH_03696 0.0 T PhoQ Sensor
MEGKGOFH_03697 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_03698 7.2e-23
MEGKGOFH_03699 2.1e-97 yvrI K RNA polymerase
MEGKGOFH_03700 2.4e-19 S YvrJ protein family
MEGKGOFH_03701 1.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
MEGKGOFH_03702 1.3e-64 yvrL S Regulatory protein YrvL
MEGKGOFH_03703 4.4e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MEGKGOFH_03704 3.5e-123 macB V ABC transporter, ATP-binding protein
MEGKGOFH_03705 2e-174 M Efflux transporter rnd family, mfp subunit
MEGKGOFH_03706 1.3e-148 fhuC 3.6.3.34 HP ABC transporter
MEGKGOFH_03707 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEGKGOFH_03708 2.1e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEGKGOFH_03709 1e-176 fhuD P ABC transporter
MEGKGOFH_03710 4.9e-236 yvsH E Arginine ornithine antiporter
MEGKGOFH_03711 6.5e-16 S Small spore protein J (Spore_SspJ)
MEGKGOFH_03712 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MEGKGOFH_03713 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MEGKGOFH_03714 3.9e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MEGKGOFH_03715 4.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MEGKGOFH_03716 9e-119 modB P COG4149 ABC-type molybdate transport system, permease component
MEGKGOFH_03717 1.7e-156 yvgN S reductase
MEGKGOFH_03718 4e-84 yvgO
MEGKGOFH_03719 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MEGKGOFH_03720 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MEGKGOFH_03721 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MEGKGOFH_03722 0.0 helD 3.6.4.12 L DNA helicase
MEGKGOFH_03723 5.4e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MEGKGOFH_03724 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MEGKGOFH_03725 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MEGKGOFH_03726 1.7e-64 ywnA K Transcriptional regulator
MEGKGOFH_03727 2e-112 ywnB S NAD(P)H-binding
MEGKGOFH_03728 8.4e-58 ywnC S Family of unknown function (DUF5362)
MEGKGOFH_03729 3.5e-143 mta K transcriptional
MEGKGOFH_03730 7.8e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEGKGOFH_03731 2.2e-70 ywnF S Family of unknown function (DUF5392)
MEGKGOFH_03732 5.7e-09 ywnC S Family of unknown function (DUF5362)
MEGKGOFH_03733 3.2e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MEGKGOFH_03734 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MEGKGOFH_03735 1.1e-33 ywnJ S VanZ like family
MEGKGOFH_03736 1e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MEGKGOFH_03737 1.6e-58 nrgB K Belongs to the P(II) protein family
MEGKGOFH_03738 2.5e-225 amt P Ammonium transporter
MEGKGOFH_03739 1.2e-77
MEGKGOFH_03740 6.8e-104 phzA Q Isochorismatase family
MEGKGOFH_03741 1.4e-240 ywoD EGP Major facilitator superfamily
MEGKGOFH_03742 4.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MEGKGOFH_03743 1.7e-228 ywoF P Right handed beta helix region
MEGKGOFH_03744 6e-211 ywoG EGP Major facilitator Superfamily
MEGKGOFH_03745 2.1e-70 ywoH K COG1846 Transcriptional regulators
MEGKGOFH_03746 3e-44 spoIIID K Stage III sporulation protein D
MEGKGOFH_03747 3.5e-180 mbl D Rod shape-determining protein
MEGKGOFH_03748 3.4e-125 flhO N flagellar basal body
MEGKGOFH_03749 2.6e-141 flhP N flagellar basal body
MEGKGOFH_03750 4.8e-196 S aspartate phosphatase
MEGKGOFH_03751 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEGKGOFH_03752 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEGKGOFH_03753 1.6e-149 ywpD T Histidine kinase
MEGKGOFH_03754 1.5e-49 srtA 3.4.22.70 M Sortase family
MEGKGOFH_03755 3.7e-33 ywpF S YwpF-like protein
MEGKGOFH_03756 3.8e-66 ywpG
MEGKGOFH_03757 3.7e-57 ssbB L Single-stranded DNA-binding protein
MEGKGOFH_03758 2.8e-185 dppD P Belongs to the ABC transporter superfamily
MEGKGOFH_03759 1.6e-85 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEGKGOFH_03760 7.3e-72 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEGKGOFH_03761 5e-154 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MEGKGOFH_03762 1.1e-152 dppA E D-aminopeptidase
MEGKGOFH_03763 1e-132 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MEGKGOFH_03764 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MEGKGOFH_03766 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MEGKGOFH_03767 3.4e-310 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEGKGOFH_03768 2.3e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MEGKGOFH_03769 1.7e-238 steT E amino acid
MEGKGOFH_03770 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MEGKGOFH_03771 5.8e-175 pit P phosphate transporter
MEGKGOFH_03772 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MEGKGOFH_03773 6.7e-23 spoIISB S Stage II sporulation protein SB
MEGKGOFH_03774 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MEGKGOFH_03775 9.3e-40 xhlB S SPP1 phage holin
MEGKGOFH_03776 1.8e-33 xhlA S Haemolysin XhlA
MEGKGOFH_03777 1.2e-154 xepA
MEGKGOFH_03778 3.8e-23 xkdX
MEGKGOFH_03779 2.6e-55 xkdW S XkdW protein
MEGKGOFH_03780 2.2e-223
MEGKGOFH_03781 3.1e-25
MEGKGOFH_03782 6.7e-41
MEGKGOFH_03783 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MEGKGOFH_03784 1.9e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MEGKGOFH_03785 1.8e-69 xkdS S Protein of unknown function (DUF2634)
MEGKGOFH_03786 4.7e-39 xkdR S Protein of unknown function (DUF2577)
MEGKGOFH_03787 1.8e-181 yqbQ 3.2.1.96 G NLP P60 protein
MEGKGOFH_03788 9.2e-121 xkdP S Lysin motif
MEGKGOFH_03789 5.6e-284 xkdO L Transglycosylase SLT domain
MEGKGOFH_03790 2.2e-29 xkdO L Transglycosylase SLT domain
MEGKGOFH_03791 0.0 dppE E ABC transporter substrate-binding protein
MEGKGOFH_03792 1.1e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MEGKGOFH_03793 5.2e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MEGKGOFH_03794 2e-166 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MEGKGOFH_03795 5.5e-186 ykfD E Belongs to the ABC transporter superfamily
MEGKGOFH_03796 3.6e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
MEGKGOFH_03797 3.5e-160 ykgA E Amidinotransferase
MEGKGOFH_03798 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MEGKGOFH_03799 4.3e-225 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MEGKGOFH_03800 3.5e-129 ykjA S Protein of unknown function (DUF421)
MEGKGOFH_03801 1.5e-97 ykkA S Protein of unknown function (DUF664)
MEGKGOFH_03802 1.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MEGKGOFH_03803 1.7e-54 ykkC P Multidrug resistance protein
MEGKGOFH_03804 9.1e-50 ykkD P Multidrug resistance protein
MEGKGOFH_03805 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MEGKGOFH_03806 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEGKGOFH_03807 1.8e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEGKGOFH_03809 1.3e-70 ohrA O Organic hydroperoxide resistance protein
MEGKGOFH_03810 1.7e-73 ohrR K COG1846 Transcriptional regulators
MEGKGOFH_03811 8.4e-72 ohrB O Organic hydroperoxide resistance protein
MEGKGOFH_03812 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MEGKGOFH_03813 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MEGKGOFH_03814 5e-176 isp O Belongs to the peptidase S8 family
MEGKGOFH_03815 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MEGKGOFH_03816 1.2e-135 ykoC P Cobalt transport protein
MEGKGOFH_03817 1.6e-307 P ABC transporter, ATP-binding protein
MEGKGOFH_03818 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
MEGKGOFH_03819 3.3e-109 ykoF S YKOF-related Family
MEGKGOFH_03820 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_03821 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MEGKGOFH_03822 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MEGKGOFH_03823 1e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MEGKGOFH_03824 9.2e-242 ymfH S zinc protease
MEGKGOFH_03825 2.4e-234 ymfF S Peptidase M16
MEGKGOFH_03826 1.5e-206 ymfD EGP Major facilitator Superfamily
MEGKGOFH_03827 1.4e-133 ymfC K Transcriptional regulator
MEGKGOFH_03828 8.4e-304 ftsK D Belongs to the FtsK SpoIIIE SftA family
MEGKGOFH_03829 3.2e-106 ftsK D Belongs to the FtsK SpoIIIE SftA family
MEGKGOFH_03830 4.4e-32 S YlzJ-like protein
MEGKGOFH_03831 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MEGKGOFH_03832 2.8e-307 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEGKGOFH_03833 1.5e-155 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEGKGOFH_03834 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MEGKGOFH_03835 1.8e-59 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEGKGOFH_03836 6.8e-119 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEGKGOFH_03837 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MEGKGOFH_03838 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MEGKGOFH_03839 2.6e-42 ymxH S YlmC YmxH family
MEGKGOFH_03840 4.4e-233 pepR S Belongs to the peptidase M16 family
MEGKGOFH_03841 8.3e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MEGKGOFH_03842 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MEGKGOFH_03843 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEGKGOFH_03844 4.3e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MEGKGOFH_03845 1.8e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEGKGOFH_03846 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEGKGOFH_03847 3e-44 ylxP S protein conserved in bacteria
MEGKGOFH_03848 1.4e-303 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEGKGOFH_03849 1.9e-58 sipW 3.4.21.89 U Signal peptidase
MEGKGOFH_03850 1.2e-140 tasA S Cell division protein FtsN
MEGKGOFH_03851 1e-54 sinR K transcriptional
MEGKGOFH_03852 1.2e-24 sinI S Anti-repressor SinI
MEGKGOFH_03853 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
MEGKGOFH_03854 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MEGKGOFH_03855 2.1e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MEGKGOFH_03856 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MEGKGOFH_03857 2.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MEGKGOFH_03858 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MEGKGOFH_03859 2.2e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MEGKGOFH_03860 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MEGKGOFH_03861 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
MEGKGOFH_03862 2.2e-61 yqhP
MEGKGOFH_03863 7.1e-110 yqhQ S Protein of unknown function (DUF1385)
MEGKGOFH_03864 1.6e-50 yqhQ S Protein of unknown function (DUF1385)
MEGKGOFH_03865 3e-93 yqhR S Conserved membrane protein YqhR
MEGKGOFH_03866 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MEGKGOFH_03867 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MEGKGOFH_03868 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEGKGOFH_03869 7.9e-37 yqhV S Protein of unknown function (DUF2619)
MEGKGOFH_03870 4e-170 spoIIIAA S stage III sporulation protein AA
MEGKGOFH_03871 1.1e-84 spoIIIAB S Stage III sporulation protein
MEGKGOFH_03872 7.6e-29 spoIIIAC S stage III sporulation protein AC
MEGKGOFH_03873 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MEGKGOFH_03874 3.8e-197 spoIIIAE S stage III sporulation protein AE
MEGKGOFH_03875 5.9e-69 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MEGKGOFH_03876 1.9e-108 spoIIIAG S stage III sporulation protein AG
MEGKGOFH_03877 1e-78 spoIIIAH S SpoIIIAH-like protein
MEGKGOFH_03878 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEGKGOFH_03879 5.9e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MEGKGOFH_03880 2.1e-67 yqhY S protein conserved in bacteria
MEGKGOFH_03881 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEGKGOFH_03882 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEGKGOFH_03883 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MEGKGOFH_03884 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEGKGOFH_03885 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEGKGOFH_03886 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEGKGOFH_03887 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEGKGOFH_03888 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
MEGKGOFH_03889 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEGKGOFH_03890 4.4e-115 sigH K Belongs to the sigma-70 factor family
MEGKGOFH_03891 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MEGKGOFH_03892 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEGKGOFH_03893 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MEGKGOFH_03894 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MEGKGOFH_03895 4.7e-67 cysE 2.3.1.30 E Serine acetyltransferase
MEGKGOFH_03896 1.4e-33 cysE 2.3.1.30 E Serine acetyltransferase
MEGKGOFH_03897 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEGKGOFH_03898 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MEGKGOFH_03899 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MEGKGOFH_03900 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MEGKGOFH_03901 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MEGKGOFH_03902 2.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEGKGOFH_03903 0.0 clpC O Belongs to the ClpA ClpB family
MEGKGOFH_03904 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MEGKGOFH_03905 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MEGKGOFH_03906 2.9e-76 ctsR K Belongs to the CtsR family
MEGKGOFH_03907 8.5e-116 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MEGKGOFH_03908 1.4e-25 XK26_06125 S Transcriptional Coactivator p15 (PC4)
MEGKGOFH_03910 2.3e-57 S Protein of unknown function, DUF600
MEGKGOFH_03911 0.0 L nucleic acid phosphodiester bond hydrolysis
MEGKGOFH_03912 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
MEGKGOFH_03913 8.7e-212 S Tetratricopeptide repeat
MEGKGOFH_03915 9.4e-127 yeeN K transcriptional regulatory protein
MEGKGOFH_03917 1.2e-103 dhaR3 K Transcriptional regulator
MEGKGOFH_03918 2.8e-81 yesE S SnoaL-like domain
MEGKGOFH_03919 1.3e-151 yesF GM NAD(P)H-binding
MEGKGOFH_03920 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
MEGKGOFH_03921 1.5e-45 cotJB S CotJB protein
MEGKGOFH_03922 5.2e-104 cotJC P Spore Coat
MEGKGOFH_03923 2.8e-99 yesJ K Acetyltransferase (GNAT) family
MEGKGOFH_03925 4.5e-101 yesL S Protein of unknown function, DUF624
MEGKGOFH_03926 0.0 yesM 2.7.13.3 T Histidine kinase
MEGKGOFH_03927 4.7e-202 yesN K helix_turn_helix, arabinose operon control protein
MEGKGOFH_03928 1e-245 yesO G Bacterial extracellular solute-binding protein
MEGKGOFH_03929 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
MEGKGOFH_03930 2.2e-162 yesQ P Binding-protein-dependent transport system inner membrane component
MEGKGOFH_03931 7.3e-189 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MEGKGOFH_03932 0.0 yesS K Transcriptional regulator
MEGKGOFH_03933 3.5e-67 glcR K COG1349 Transcriptional regulators of sugar metabolism
MEGKGOFH_03934 3.9e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MEGKGOFH_03935 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MEGKGOFH_03936 1.4e-308 ywqB S SWIM zinc finger
MEGKGOFH_03937 1.2e-17
MEGKGOFH_03938 2e-116 ywqC M biosynthesis protein
MEGKGOFH_03939 8.3e-56 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MEGKGOFH_03940 1.7e-42 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MEGKGOFH_03941 5.1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MEGKGOFH_03942 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MEGKGOFH_03943 1.4e-152 ywqG S Domain of unknown function (DUF1963)
MEGKGOFH_03944 9.7e-23 S Domain of unknown function (DUF5082)
MEGKGOFH_03945 2.5e-37 ywqI S Family of unknown function (DUF5344)
MEGKGOFH_03946 2.1e-242 ywqJ S Pre-toxin TG
MEGKGOFH_03947 3.9e-25
MEGKGOFH_03948 3.9e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MEGKGOFH_03949 1.4e-161 K Transcriptional regulator
MEGKGOFH_03950 4.6e-08 ywqN S NAD(P)H-dependent
MEGKGOFH_03951 8.3e-81 ywqN S NAD(P)H-dependent
MEGKGOFH_03953 6.4e-88 ywrA P COG2059 Chromate transport protein ChrA
MEGKGOFH_03954 1.2e-103 ywrB P Chromate transporter
MEGKGOFH_03955 8e-82 ywrC K Transcriptional regulator
MEGKGOFH_03956 2.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MEGKGOFH_03957 5e-54 S Domain of unknown function (DUF4181)
MEGKGOFH_03958 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MEGKGOFH_03959 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MEGKGOFH_03960 1.1e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MEGKGOFH_03961 1.4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
MEGKGOFH_03962 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MEGKGOFH_03963 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEGKGOFH_03964 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEGKGOFH_03965 4.5e-88 yaiI S Belongs to the UPF0178 family
MEGKGOFH_03966 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MEGKGOFH_03967 4.5e-112 ccpN K CBS domain
MEGKGOFH_03968 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MEGKGOFH_03969 8.3e-13 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MEGKGOFH_03970 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MEGKGOFH_03971 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
MEGKGOFH_03972 8.4e-19 S YqzL-like protein
MEGKGOFH_03973 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEGKGOFH_03974 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MEGKGOFH_03975 3.4e-58 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MEGKGOFH_03976 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEGKGOFH_03977 0.0 yqfF S membrane-associated HD superfamily hydrolase
MEGKGOFH_03978 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
MEGKGOFH_03979 3.1e-84 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MEGKGOFH_03980 9.7e-64 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MEGKGOFH_03981 2.7e-45 yqfC S sporulation protein YqfC
MEGKGOFH_03982 5.4e-16 yqfB
MEGKGOFH_03983 9.9e-109 yokF 3.1.31.1 L RNA catabolic process
MEGKGOFH_03984 5.1e-292 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MEGKGOFH_03985 6.4e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MEGKGOFH_03986 5.6e-214 xylR GK ROK family
MEGKGOFH_03987 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MEGKGOFH_03988 3.9e-254 xynT G MFS/sugar transport protein
MEGKGOFH_03989 2.7e-82 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MEGKGOFH_03992 7.1e-110 ynaE S Domain of unknown function (DUF3885)
MEGKGOFH_03993 1.5e-22 K Cro/C1-type HTH DNA-binding domain
MEGKGOFH_03994 5.2e-07 S Uncharacterised protein family (UPF0715)
MEGKGOFH_03995 3.6e-75 S CAAX protease self-immunity
MEGKGOFH_03996 5e-81 ynaD J Acetyltransferase (GNAT) domain
MEGKGOFH_03998 1.9e-216 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
MEGKGOFH_03999 1.3e-196 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MEGKGOFH_04000 2.2e-120 H Methionine biosynthesis protein MetW
MEGKGOFH_04001 2.2e-93 M Glycosyltransferase like family
MEGKGOFH_04002 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MEGKGOFH_04003 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MEGKGOFH_04004 2.7e-109 ykoX S membrane-associated protein
MEGKGOFH_04005 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
MEGKGOFH_04006 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MEGKGOFH_04007 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MEGKGOFH_04008 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MEGKGOFH_04009 0.0 ykoS
MEGKGOFH_04010 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MEGKGOFH_04011 1.1e-98 ykoP G polysaccharide deacetylase
MEGKGOFH_04012 2e-216 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MEGKGOFH_04013 1.3e-81 mhqR K transcriptional
MEGKGOFH_04014 6.9e-26 ykoL
MEGKGOFH_04015 5.9e-18
MEGKGOFH_04016 1.4e-53 tnrA K transcriptional
MEGKGOFH_04017 2.2e-222 mgtE P Acts as a magnesium transporter
MEGKGOFH_04020 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
MEGKGOFH_04021 2e-36 ykoI S Peptidase propeptide and YPEB domain
MEGKGOFH_04022 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
MEGKGOFH_04023 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MEGKGOFH_04024 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MEGKGOFH_04025 9.6e-175 yqjA S Putative aromatic acid exporter C-terminal domain
MEGKGOFH_04026 1.8e-98 yqjB S protein conserved in bacteria
MEGKGOFH_04028 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MEGKGOFH_04029 8e-285 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MEGKGOFH_04030 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MEGKGOFH_04031 2.9e-139 yqjF S Uncharacterized conserved protein (COG2071)
MEGKGOFH_04032 3.6e-128 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MEGKGOFH_04033 6.4e-154 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MEGKGOFH_04034 5.5e-239 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Histidine ammonia-lyase
MEGKGOFH_04035 1e-99 IQ reductase
MEGKGOFH_04036 3.9e-16 6.1.1.13, 6.2.1.50 IQ Phosphopantetheine attachment site
MEGKGOFH_04037 4e-162 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEGKGOFH_04038 6e-139 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEGKGOFH_04039 3.2e-65 yodA S tautomerase
MEGKGOFH_04040 5e-162 gltR K LysR substrate binding domain
MEGKGOFH_04041 5.6e-226 brnQ E Component of the transport system for branched-chain amino acids
MEGKGOFH_04042 5.6e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MEGKGOFH_04043 2.8e-137 azlC E AzlC protein
MEGKGOFH_04044 6.3e-79 bkdR K helix_turn_helix ASNC type
MEGKGOFH_04045 1.2e-15 yrdF K ribonuclease inhibitor
MEGKGOFH_04046 9.2e-231 cypA C Cytochrome P450
MEGKGOFH_04048 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
MEGKGOFH_04049 5e-55 S Protein of unknown function (DUF2568)
MEGKGOFH_04050 2.4e-89 yrdA S DinB family
MEGKGOFH_04051 4.6e-165 aadK G Streptomycin adenylyltransferase
MEGKGOFH_04052 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MEGKGOFH_04054 2.7e-140 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MEGKGOFH_04055 1.6e-123 yrpD S Domain of unknown function, YrpD
MEGKGOFH_04056 3.1e-85 gerLC S Spore germination protein
MEGKGOFH_04057 1.9e-80 gerLC S Spore germination protein
MEGKGOFH_04058 2.9e-153 yndG S DoxX-like family
MEGKGOFH_04059 2.6e-115 yndH S Domain of unknown function (DUF4166)
MEGKGOFH_04060 4.5e-310 yndJ S YndJ-like protein
MEGKGOFH_04062 5.2e-136 yndL S Replication protein
MEGKGOFH_04063 5.8e-74 yndM S Protein of unknown function (DUF2512)
MEGKGOFH_04064 5.1e-64 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MEGKGOFH_04065 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEGKGOFH_04066 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MEGKGOFH_04067 4.5e-112 yneB L resolvase
MEGKGOFH_04068 1.3e-32 ynzC S UPF0291 protein
MEGKGOFH_04069 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEGKGOFH_04070 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MEGKGOFH_04071 1.8e-28 yneF S UPF0154 protein
MEGKGOFH_04072 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MEGKGOFH_04073 2.6e-99 ccdA O cytochrome c biogenesis protein
MEGKGOFH_04075 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MEGKGOFH_04076 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MEGKGOFH_04077 7.2e-74 yneK S Protein of unknown function (DUF2621)
MEGKGOFH_04078 5.9e-64 hspX O Spore coat protein
MEGKGOFH_04079 1e-181 yaaC S YaaC-like Protein
MEGKGOFH_04080 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MEGKGOFH_04081 8.9e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MEGKGOFH_04082 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MEGKGOFH_04083 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MEGKGOFH_04084 1.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEGKGOFH_04085 1.3e-09
MEGKGOFH_04086 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MEGKGOFH_04087 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MEGKGOFH_04088 2e-212 yaaH M Glycoside Hydrolase Family
MEGKGOFH_04089 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
MEGKGOFH_04090 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEGKGOFH_04091 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEGKGOFH_04092 4.6e-161 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEGKGOFH_04094 1.2e-189 S aspartate phosphatase
MEGKGOFH_04095 9.2e-37 S Bacteriophage holin
MEGKGOFH_04097 5.4e-75 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MEGKGOFH_04098 2.7e-55 S outer membrane
MEGKGOFH_04099 4.7e-98
MEGKGOFH_04100 2.1e-301 S Pfam Transposase IS66
MEGKGOFH_04101 3.8e-86 S Phage tail protein
MEGKGOFH_04102 5.7e-133 S peptidoglycan catabolic process
MEGKGOFH_04108 7.8e-08
MEGKGOFH_04116 2e-08
MEGKGOFH_04120 2.7e-143 spo0M S COG4326 Sporulation control protein
MEGKGOFH_04121 1.2e-26
MEGKGOFH_04122 1.4e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MEGKGOFH_04123 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MEGKGOFH_04124 9.3e-261 ygaK C Berberine and berberine like
MEGKGOFH_04126 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MEGKGOFH_04127 3.9e-145 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MEGKGOFH_04128 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MEGKGOFH_04130 5e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MEGKGOFH_04131 4.7e-39
MEGKGOFH_04133 6.2e-73 sdpB S Protein conserved in bacteria
MEGKGOFH_04134 1.8e-27
MEGKGOFH_04136 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MEGKGOFH_04137 1.1e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MEGKGOFH_04138 0.0 ydaO E amino acid
MEGKGOFH_04139 6e-115 ydaN S Bacterial cellulose synthase subunit
MEGKGOFH_04140 2.5e-236 Q Non-ribosomal peptide synthetase modules and related proteins
MEGKGOFH_04141 2e-228 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MEGKGOFH_04142 1.1e-250 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MEGKGOFH_04143 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MEGKGOFH_04144 2.1e-149 ybbH K transcriptional
MEGKGOFH_04145 3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MEGKGOFH_04146 1.9e-86 ybbJ J acetyltransferase
MEGKGOFH_04147 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MEGKGOFH_04153 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MEGKGOFH_04154 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MEGKGOFH_04155 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEGKGOFH_04156 5.6e-64 czcD P COG1230 Co Zn Cd efflux system component
MEGKGOFH_04157 3.3e-197 trkA P Oxidoreductase
MEGKGOFH_04158 1.6e-157 yrdQ K Transcriptional regulator
MEGKGOFH_04159 4.1e-170 yrdR EG EamA-like transporter family
MEGKGOFH_04160 3.9e-16 S YrzO-like protein
MEGKGOFH_04161 5.5e-206 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MEGKGOFH_04162 5.9e-82 bltD 2.3.1.57 K FR47-like protein
MEGKGOFH_04163 3.5e-211 blt EGP Major facilitator Superfamily
MEGKGOFH_04164 3.4e-149 bltR K helix_turn_helix, mercury resistance
MEGKGOFH_04165 1.3e-107 yrkC G Cupin domain
MEGKGOFH_04166 7.8e-39 yrkD S protein conserved in bacteria
MEGKGOFH_04167 4.3e-83 yrkE O DsrE/DsrF/DrsH-like family
MEGKGOFH_04168 1.1e-75 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MEGKGOFH_04169 7.8e-238 ybbC 3.2.1.52 S protein conserved in bacteria
MEGKGOFH_04170 9.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MEGKGOFH_04171 6.2e-137 feuA P Iron-uptake system-binding protein
MEGKGOFH_04172 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEGKGOFH_04173 1.6e-140 ybbA S Putative esterase
MEGKGOFH_04174 6e-161 ybaS 1.1.1.58 S Na -dependent transporter
MEGKGOFH_04176 1.5e-245 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MEGKGOFH_04179 3.3e-70
MEGKGOFH_04182 1.2e-67
MEGKGOFH_04183 1.3e-90
MEGKGOFH_04184 8.1e-131
MEGKGOFH_04185 1.3e-89
MEGKGOFH_04188 3.8e-52
MEGKGOFH_04189 9.7e-31
MEGKGOFH_04192 1.7e-19
MEGKGOFH_04193 9.6e-20
MEGKGOFH_04194 8.9e-61
MEGKGOFH_04195 1.2e-191 xerH A Belongs to the 'phage' integrase family
MEGKGOFH_04198 7e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MEGKGOFH_04199 1.2e-138 xtmA L phage terminase small subunit
MEGKGOFH_04200 3.1e-253 xtmB S phage terminase, large subunit
MEGKGOFH_04201 5.4e-286 yqbA S portal protein
MEGKGOFH_04202 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MEGKGOFH_04203 5.8e-169 xkdG S Phage capsid family
MEGKGOFH_04204 4.3e-62 yqbG S Protein of unknown function (DUF3199)
MEGKGOFH_04205 8.7e-65 yqbH S Domain of unknown function (DUF3599)
MEGKGOFH_04206 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
MEGKGOFH_04207 1.9e-77 xkdJ
MEGKGOFH_04208 2.5e-256 xkdK S Phage tail sheath C-terminal domain
MEGKGOFH_04209 6.1e-76 xkdM S Phage tail tube protein
MEGKGOFH_04210 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
MEGKGOFH_04211 6.3e-130 E GDSL-like Lipase/Acylhydrolase
MEGKGOFH_04212 8.7e-127 yesU S Domain of unknown function (DUF1961)
MEGKGOFH_04213 9.7e-112 yesV S Protein of unknown function, DUF624
MEGKGOFH_04214 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MEGKGOFH_04215 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MEGKGOFH_04216 3.2e-110 yesY E GDSL-like Lipase/Acylhydrolase
MEGKGOFH_04217 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
MEGKGOFH_04218 3.1e-55 K DNA binding
MEGKGOFH_04222 2.3e-35
MEGKGOFH_04225 4e-31
MEGKGOFH_04226 3.1e-13 bet L RecT family
MEGKGOFH_04227 1.5e-16
MEGKGOFH_04228 1.2e-11
MEGKGOFH_04229 4.7e-09 S Helix-turn-helix domain
MEGKGOFH_04230 6.1e-11 K Helix-turn-helix XRE-family like proteins
MEGKGOFH_04231 4.7e-49 bldD K domain, Protein
MEGKGOFH_04232 9.6e-25
MEGKGOFH_04233 9.3e-16 xkdA E IrrE N-terminal-like domain
MEGKGOFH_04234 1.4e-29 L Phage integrase, N-terminal SAM-like domain
MEGKGOFH_04235 2.1e-38 L Phage integrase, N-terminal SAM-like domain
MEGKGOFH_04238 1.1e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEGKGOFH_04240 7.3e-209 S Calcineurin-like phosphoesterase superfamily domain
MEGKGOFH_04243 1.1e-16
MEGKGOFH_04244 9.6e-109
MEGKGOFH_04245 3.1e-18
MEGKGOFH_04246 1e-35
MEGKGOFH_04250 5.7e-71 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MEGKGOFH_04251 9.8e-36 O Glutaredoxin
MEGKGOFH_04252 5.4e-181 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEGKGOFH_04254 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEGKGOFH_04255 3.3e-95 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEGKGOFH_04256 5.8e-62 S NrdI Flavodoxin like
MEGKGOFH_04263 3e-158 3.1.21.3 L Domain of unknown function (DUF4942)
MEGKGOFH_04264 2.1e-18 3.1.21.3 L Domain of unknown function (DUF4942)
MEGKGOFH_04271 6.6e-09 S Uncharacterised protein family (UPF0715)
MEGKGOFH_04273 1.3e-93
MEGKGOFH_04278 1.1e-17
MEGKGOFH_04279 1.3e-109
MEGKGOFH_04280 1.1e-55 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MEGKGOFH_04281 1.9e-163 S Thymidylate synthase
MEGKGOFH_04283 3.2e-133 S Domain of unknown function, YrpD
MEGKGOFH_04286 7.9e-25 tatA U protein secretion
MEGKGOFH_04287 1.8e-71
MEGKGOFH_04288 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MEGKGOFH_04291 1.4e-284 gerAA EG Spore germination protein
MEGKGOFH_04292 3.7e-82 gerAB U Spore germination
MEGKGOFH_04293 1.3e-99 gerAB U Spore germination
MEGKGOFH_04296 9.2e-92 S Protein of unknown function (DUF1273)
MEGKGOFH_04297 6.2e-12 S YopX protein
MEGKGOFH_04299 4.7e-09 S YopX protein
MEGKGOFH_04302 2.8e-75
MEGKGOFH_04303 6.1e-13 S Hypothetical protein (DUF2513)
MEGKGOFH_04305 2.6e-149 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
MEGKGOFH_04306 4e-104 yoqW S Belongs to the SOS response-associated peptidase family
MEGKGOFH_04308 0.0 2.7.7.7 L DNA polymerase
MEGKGOFH_04309 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MEGKGOFH_04310 1.2e-221 L DNA primase activity
MEGKGOFH_04311 3.7e-134 3.6.4.12 J DnaB-like helicase C terminal domain
MEGKGOFH_04312 1.7e-09
MEGKGOFH_04318 4.3e-21
MEGKGOFH_04322 1.1e-33 K Transcriptional regulator
MEGKGOFH_04323 2.1e-177
MEGKGOFH_04324 2.3e-34 S DNA-sulfur modification-associated
MEGKGOFH_04325 6.9e-198 S DNA-sulfur modification-associated
MEGKGOFH_04326 1.3e-162 L Belongs to the 'phage' integrase family
MEGKGOFH_04327 5.4e-53 S YolD-like protein
MEGKGOFH_04328 8.9e-59 L nuclease activity
MEGKGOFH_04329 1.5e-85 S SMI1-KNR4 cell-wall
MEGKGOFH_04330 6.4e-296 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MEGKGOFH_04331 1.3e-20 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MEGKGOFH_04332 3.7e-121 V HNH endonuclease
MEGKGOFH_04333 2.8e-62 G SMI1-KNR4 cell-wall
MEGKGOFH_04334 1.9e-34
MEGKGOFH_04338 3.9e-88 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEGKGOFH_04339 5.8e-43 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEGKGOFH_04341 1.1e-13 S SNARE associated Golgi protein
MEGKGOFH_04342 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MEGKGOFH_04343 6.2e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MEGKGOFH_04344 3e-35 ypuD
MEGKGOFH_04345 6.5e-74
MEGKGOFH_04346 4.6e-23
MEGKGOFH_04347 1.3e-291
MEGKGOFH_04349 0.0 msbA2 3.6.3.44 V ABC transporter
MEGKGOFH_04350 4.2e-275 S COG0457 FOG TPR repeat
MEGKGOFH_04352 8.3e-30
MEGKGOFH_04354 4.4e-18 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MEGKGOFH_04355 1e-15
MEGKGOFH_04356 2e-40
MEGKGOFH_04357 4.6e-174 A Pre-toxin TG
MEGKGOFH_04359 5.7e-25
MEGKGOFH_04360 9.3e-59
MEGKGOFH_04361 2e-08
MEGKGOFH_04373 4.3e-93 S methyltransferase activity
MEGKGOFH_04374 4.6e-80 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
MEGKGOFH_04379 2.3e-50 DR0488 S protein conserved in bacteria
MEGKGOFH_04380 3.4e-31 csfB S Inhibitor of sigma-G Gin
MEGKGOFH_04381 2e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MEGKGOFH_04382 8.4e-202 yaaN P Belongs to the TelA family
MEGKGOFH_04383 2.7e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MEGKGOFH_04384 3.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEGKGOFH_04389 5.6e-129
MEGKGOFH_04391 2.2e-31 yoaF
MEGKGOFH_04392 7.7e-10
MEGKGOFH_04393 5e-36
MEGKGOFH_04394 9.5e-50 FG Scavenger mRNA decapping enzyme C-term binding
MEGKGOFH_04396 2e-85
MEGKGOFH_04397 7.6e-180 L AAA domain
MEGKGOFH_04398 4.7e-155
MEGKGOFH_04403 1.6e-54 M Parallel beta-helix repeats
MEGKGOFH_04404 2.6e-130 srfAC Q Thioesterase domain
MEGKGOFH_04406 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEGKGOFH_04407 4.5e-24 yqzJ
MEGKGOFH_04408 5.2e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MEGKGOFH_04409 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
MEGKGOFH_04410 3.8e-10
MEGKGOFH_04411 1e-31
MEGKGOFH_04412 1.7e-93
MEGKGOFH_04413 2.1e-14 L GIY-YIG type nucleases (URI domain)
MEGKGOFH_04414 0.0
MEGKGOFH_04416 1.2e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
MEGKGOFH_04418 4.2e-206 yrkH P Rhodanese Homology Domain
MEGKGOFH_04419 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
MEGKGOFH_04420 1.2e-114 yrkJ S membrane transporter protein
MEGKGOFH_04421 3.4e-55 M Parallel beta-helix repeats
MEGKGOFH_04422 4.5e-239 M Parallel beta-helix repeats
MEGKGOFH_04423 1.4e-145 S Pfam:DUF867
MEGKGOFH_04425 3.2e-74
MEGKGOFH_04429 1e-202
MEGKGOFH_04430 2.9e-94 S aspartate phosphatase
MEGKGOFH_04431 9.5e-80 S SMI1-KNR4 cell-wall
MEGKGOFH_04432 1.5e-35 S Protein of unknown function (DUF1433)
MEGKGOFH_04433 1.9e-87 I Pfam Lipase (class 3)
MEGKGOFH_04434 3.4e-39 S COG NOG14552 non supervised orthologous group
MEGKGOFH_04435 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MEGKGOFH_04436 9e-47 L Phage integrase, N-terminal SAM-like domain
MEGKGOFH_04437 4.7e-100 S peptidoglycan catabolic process
MEGKGOFH_04439 1.1e-29
MEGKGOFH_04440 3.4e-50 S Pfam Transposase IS66
MEGKGOFH_04441 3.8e-11 csbD K CsbD-like
MEGKGOFH_04442 3e-84 ywmF S Peptidase M50
MEGKGOFH_04443 1.3e-103 S response regulator aspartate phosphatase
MEGKGOFH_04444 2.6e-104 I Pfam Lipase (class 3)
MEGKGOFH_04445 9e-31
MEGKGOFH_04447 8.5e-16 K Helix-turn-helix domain
MEGKGOFH_04449 1.1e-52 ykoH 2.7.13.3 T Histidine kinase
MEGKGOFH_04450 1.5e-170 ykoH 2.7.13.3 T Histidine kinase
MEGKGOFH_04451 1.4e-36 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MEGKGOFH_04452 1.3e-08 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MEGKGOFH_04453 2.6e-123 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MEGKGOFH_04454 5e-47 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MEGKGOFH_04455 3.5e-87 hsdS 3.1.21.3 V DNA specificity domain
MEGKGOFH_04458 1.8e-35 bofA S Sigma-K factor-processing regulatory protein BofA
MEGKGOFH_04459 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MEGKGOFH_04460 1.3e-93 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEGKGOFH_04461 1.1e-27 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MEGKGOFH_04464 1.8e-36
MEGKGOFH_04466 1.8e-08 K Cro/C1-type HTH DNA-binding domain
MEGKGOFH_04474 2e-08
MEGKGOFH_04479 1e-76 S Protein of unknown function (DUF3800)
MEGKGOFH_04483 1.1e-49 S Phage tail protein
MEGKGOFH_04486 1.4e-13
MEGKGOFH_04495 1.4e-20 K Cro/C1-type HTH DNA-binding domain
MEGKGOFH_04496 2.4e-73
MEGKGOFH_04497 3.4e-39 S COG NOG14552 non supervised orthologous group

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)