ORF_ID e_value Gene_name EC_number CAZy COGs Description
HIMKHNBD_00001 2.2e-185 xkdO L Transglycosylase SLT domain
HIMKHNBD_00002 3.2e-69 xkdP S Lysin motif
HIMKHNBD_00003 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
HIMKHNBD_00004 7.2e-32 xkdR S Protein of unknown function (DUF2577)
HIMKHNBD_00005 1.4e-58 xkdS S Protein of unknown function (DUF2634)
HIMKHNBD_00006 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HIMKHNBD_00007 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HIMKHNBD_00008 1.2e-26
HIMKHNBD_00009 1.7e-91
HIMKHNBD_00011 1.6e-28 xkdX
HIMKHNBD_00012 1.4e-136 xepA
HIMKHNBD_00013 8e-38 xhlB S SPP1 phage holin
HIMKHNBD_00014 4.6e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMKHNBD_00015 8.7e-23 spoIISB S Stage II sporulation protein SB
HIMKHNBD_00016 1.7e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HIMKHNBD_00017 5.5e-22 pit P phosphate transporter
HIMKHNBD_00018 5.5e-137 pit P phosphate transporter
HIMKHNBD_00019 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HIMKHNBD_00020 1.1e-242 steT E amino acid
HIMKHNBD_00021 8.2e-179 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HIMKHNBD_00022 3.1e-284 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HIMKHNBD_00023 5.4e-116 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMKHNBD_00024 2.4e-50 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMKHNBD_00026 4.3e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIMKHNBD_00027 1.3e-277 yubD P Major Facilitator Superfamily
HIMKHNBD_00028 3.7e-82 dppA E D-aminopeptidase
HIMKHNBD_00029 3.1e-53 dppA E D-aminopeptidase
HIMKHNBD_00030 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMKHNBD_00031 5.5e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMKHNBD_00032 1.5e-189 dppD P Belongs to the ABC transporter superfamily
HIMKHNBD_00033 0.0 dppE E ABC transporter substrate-binding protein
HIMKHNBD_00034 3.7e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HIMKHNBD_00035 2.4e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HIMKHNBD_00036 4.6e-45 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HIMKHNBD_00037 1.5e-109 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HIMKHNBD_00038 1.1e-181 ykfD E Belongs to the ABC transporter superfamily
HIMKHNBD_00039 1.1e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
HIMKHNBD_00040 1.6e-157 ykgA E Amidinotransferase
HIMKHNBD_00041 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HIMKHNBD_00042 1.1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HIMKHNBD_00043 1.4e-51 ykkC P Multidrug resistance protein
HIMKHNBD_00044 1e-48 ykkD P Multidrug resistance protein
HIMKHNBD_00045 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HIMKHNBD_00046 5.1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HIMKHNBD_00047 4.5e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HIMKHNBD_00048 4.1e-69 ohrA O Organic hydroperoxide resistance protein
HIMKHNBD_00049 1.9e-76 ohrR K COG1846 Transcriptional regulators
HIMKHNBD_00050 4.2e-71 ohrB O Organic hydroperoxide resistance protein
HIMKHNBD_00051 6e-54 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HIMKHNBD_00053 9.3e-214 M Glycosyl transferase family 2
HIMKHNBD_00054 2.8e-124 M PFAM Collagen triple helix repeat (20 copies)
HIMKHNBD_00055 1.2e-214 hcaT 1.5.1.2 EGP Major facilitator Superfamily
HIMKHNBD_00056 7.5e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HIMKHNBD_00057 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HIMKHNBD_00058 5e-176 isp O Belongs to the peptidase S8 family
HIMKHNBD_00059 4.3e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIMKHNBD_00060 1.2e-132 ykoC P Cobalt transport protein
HIMKHNBD_00061 4.7e-299 P ABC transporter, ATP-binding protein
HIMKHNBD_00062 1e-97 ykoE S ABC-type cobalt transport system, permease component
HIMKHNBD_00063 7.4e-244 ydhD M Glycosyl hydrolase
HIMKHNBD_00065 3.2e-237 mgtE P Acts as a magnesium transporter
HIMKHNBD_00066 1.4e-39 tnrA K transcriptional
HIMKHNBD_00067 1.9e-16
HIMKHNBD_00068 3.1e-26 ykoL
HIMKHNBD_00069 5e-81 ykoM K transcriptional
HIMKHNBD_00070 4.6e-22 ykoP G polysaccharide deacetylase
HIMKHNBD_00071 3.5e-51 ykoP G polysaccharide deacetylase
HIMKHNBD_00072 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HIMKHNBD_00073 4.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HIMKHNBD_00074 5e-99 ykoX S membrane-associated protein
HIMKHNBD_00075 9.5e-133 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HIMKHNBD_00076 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMKHNBD_00077 1.6e-103 rsgI S Anti-sigma factor N-terminus
HIMKHNBD_00079 2.5e-26 sspD S small acid-soluble spore protein
HIMKHNBD_00080 2.9e-125 ykrK S Domain of unknown function (DUF1836)
HIMKHNBD_00081 7.8e-155 htpX O Belongs to the peptidase M48B family
HIMKHNBD_00082 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
HIMKHNBD_00083 7.2e-113 ydfR S Protein of unknown function (DUF421)
HIMKHNBD_00084 8.7e-23 ykzE
HIMKHNBD_00085 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HIMKHNBD_00086 0.0 kinE 2.7.13.3 T Histidine kinase
HIMKHNBD_00087 2e-69 kinE 2.7.13.3 T Histidine kinase
HIMKHNBD_00088 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIMKHNBD_00090 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HIMKHNBD_00091 5.5e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HIMKHNBD_00092 3.8e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HIMKHNBD_00093 1.8e-223 mtnE 2.6.1.83 E Aminotransferase
HIMKHNBD_00094 8.7e-226 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HIMKHNBD_00095 1.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HIMKHNBD_00096 2.3e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HIMKHNBD_00097 7.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HIMKHNBD_00098 3.4e-10 S Spo0E like sporulation regulatory protein
HIMKHNBD_00099 9.6e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HIMKHNBD_00100 7e-75 ykvE K transcriptional
HIMKHNBD_00101 3e-126 motB N Flagellar motor protein
HIMKHNBD_00102 3.3e-136 motA N flagellar motor
HIMKHNBD_00103 0.0 clpE O Belongs to the ClpA ClpB family
HIMKHNBD_00104 5.1e-182 ykvI S membrane
HIMKHNBD_00105 2.2e-183
HIMKHNBD_00106 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HIMKHNBD_00107 1.7e-78 queD 4.1.2.50, 4.2.3.12 H synthase
HIMKHNBD_00108 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HIMKHNBD_00109 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HIMKHNBD_00110 3.5e-45 ykvR S Protein of unknown function (DUF3219)
HIMKHNBD_00111 7.8e-25 ykvS S protein conserved in bacteria
HIMKHNBD_00112 3.9e-27
HIMKHNBD_00113 6.9e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
HIMKHNBD_00114 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMKHNBD_00115 1.7e-87 stoA CO thiol-disulfide
HIMKHNBD_00116 5.5e-90 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HIMKHNBD_00117 9.7e-231 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HIMKHNBD_00118 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HIMKHNBD_00120 7.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
HIMKHNBD_00121 5.1e-156 glcT K antiterminator
HIMKHNBD_00122 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMKHNBD_00123 2.1e-39 ptsH G phosphocarrier protein HPr
HIMKHNBD_00124 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIMKHNBD_00125 6.1e-38 splA S Transcriptional regulator
HIMKHNBD_00126 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
HIMKHNBD_00127 1.9e-262 mcpC NT chemotaxis protein
HIMKHNBD_00128 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HIMKHNBD_00129 9.8e-114 ykwD J protein with SCP PR1 domains
HIMKHNBD_00130 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HIMKHNBD_00131 1.5e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
HIMKHNBD_00132 3.9e-215 patA 2.6.1.1 E Aminotransferase
HIMKHNBD_00133 2.3e-09
HIMKHNBD_00134 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
HIMKHNBD_00135 1.4e-83 ykyB S YkyB-like protein
HIMKHNBD_00136 1.1e-239 ykuC EGP Major facilitator Superfamily
HIMKHNBD_00137 4.1e-89 ykuD S protein conserved in bacteria
HIMKHNBD_00138 9.2e-153 ykuE S Metallophosphoesterase
HIMKHNBD_00139 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMKHNBD_00141 3.3e-233 ykuI T Diguanylate phosphodiesterase
HIMKHNBD_00142 3.9e-37 ykuJ S protein conserved in bacteria
HIMKHNBD_00143 1.4e-92 ykuK S Ribonuclease H-like
HIMKHNBD_00144 2.1e-25 ykzF S Antirepressor AbbA
HIMKHNBD_00145 1e-75 ykuL S CBS domain
HIMKHNBD_00146 1.3e-167 ccpC K Transcriptional regulator
HIMKHNBD_00147 1.3e-89 fld C Flavodoxin
HIMKHNBD_00148 5.7e-166 ykuO
HIMKHNBD_00149 6e-79 fld C Flavodoxin
HIMKHNBD_00150 4.5e-73 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HIMKHNBD_00151 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HIMKHNBD_00152 4.8e-38 ykuS S Belongs to the UPF0180 family
HIMKHNBD_00153 3.7e-140 ykuT M Mechanosensitive ion channel
HIMKHNBD_00154 1.3e-76 ykuV CO thiol-disulfide
HIMKHNBD_00155 4.5e-98 rok K Repressor of ComK
HIMKHNBD_00156 7.5e-159 yknT
HIMKHNBD_00157 2.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HIMKHNBD_00158 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HIMKHNBD_00159 3.2e-242 moeA 2.10.1.1 H molybdopterin
HIMKHNBD_00160 3.2e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HIMKHNBD_00161 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HIMKHNBD_00162 1.7e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HIMKHNBD_00163 4.3e-100 yknW S Yip1 domain
HIMKHNBD_00165 2.3e-105 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HIMKHNBD_00166 2e-121 macB V ABC transporter, ATP-binding protein
HIMKHNBD_00167 3e-210 yknZ V ABC transporter (permease)
HIMKHNBD_00168 1.7e-131 fruR K Transcriptional regulator
HIMKHNBD_00169 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HIMKHNBD_00170 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HIMKHNBD_00171 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HIMKHNBD_00172 1.7e-36 ykoA
HIMKHNBD_00173 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HIMKHNBD_00174 7.6e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIMKHNBD_00175 4.7e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HIMKHNBD_00176 5.5e-12 S Uncharacterized protein YkpC
HIMKHNBD_00177 6.9e-184 mreB D Rod-share determining protein MreBH
HIMKHNBD_00178 2.2e-16 abrB K of stationary sporulation gene expression
HIMKHNBD_00179 3.4e-244 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HIMKHNBD_00180 5e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HIMKHNBD_00181 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
HIMKHNBD_00182 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HIMKHNBD_00183 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIMKHNBD_00184 8.2e-31 ykzG S Belongs to the UPF0356 family
HIMKHNBD_00185 7.4e-146 ykrA S hydrolases of the HAD superfamily
HIMKHNBD_00186 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIMKHNBD_00188 2.2e-56 recN L Putative cell-wall binding lipoprotein
HIMKHNBD_00189 3.3e-22 recN L Putative cell-wall binding lipoprotein
HIMKHNBD_00190 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HIMKHNBD_00191 0.0 Q Polyketide synthase of type I
HIMKHNBD_00192 0.0 Q Polyketide synthase of type I
HIMKHNBD_00193 0.0 Q Polyketide synthase of type I
HIMKHNBD_00194 0.0 Q polyketide synthase
HIMKHNBD_00195 0.0 Q Polyketide synthase of type I
HIMKHNBD_00196 3.4e-150 Q Polyketide synthase of type I
HIMKHNBD_00197 0.0 Q Polyketide synthase of type I
HIMKHNBD_00198 0.0 Q Polyketide synthase of type I
HIMKHNBD_00199 2.5e-178 Q Polyketide synthase of type I
HIMKHNBD_00200 0.0 Q Polyketide synthase of type I
HIMKHNBD_00201 8.7e-303 Q Polyketide synthase of type I
HIMKHNBD_00202 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
HIMKHNBD_00203 7.4e-208 V Beta-lactamase
HIMKHNBD_00204 1e-157 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HIMKHNBD_00205 9.3e-19 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HIMKHNBD_00206 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HIMKHNBD_00207 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIMKHNBD_00208 1.2e-250 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HIMKHNBD_00209 1.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HIMKHNBD_00210 1.4e-119 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
HIMKHNBD_00211 3.2e-275 speA 4.1.1.19 E Arginine
HIMKHNBD_00212 1.6e-42 yktA S Belongs to the UPF0223 family
HIMKHNBD_00213 1.8e-118 yktB S Belongs to the UPF0637 family
HIMKHNBD_00214 6.3e-24 ykzI
HIMKHNBD_00215 2.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
HIMKHNBD_00216 6.8e-83 ykzC S Acetyltransferase (GNAT) family
HIMKHNBD_00217 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HIMKHNBD_00218 9.8e-187 ylaA
HIMKHNBD_00219 1.9e-43 ylaB
HIMKHNBD_00220 1.2e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HIMKHNBD_00221 1.8e-12 sigC S Putative zinc-finger
HIMKHNBD_00222 4.5e-37 ylaE
HIMKHNBD_00223 1.5e-23 S Family of unknown function (DUF5325)
HIMKHNBD_00224 6.7e-295 typA T GTP-binding protein TypA
HIMKHNBD_00225 6.2e-39 typA T GTP-binding protein TypA
HIMKHNBD_00226 6.6e-48 ylaH S YlaH-like protein
HIMKHNBD_00227 1.4e-33 ylaI S protein conserved in bacteria
HIMKHNBD_00228 5.2e-54 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIMKHNBD_00229 6e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HIMKHNBD_00230 4.2e-83 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HIMKHNBD_00231 3.9e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
HIMKHNBD_00232 8.7e-44 ylaN S Belongs to the UPF0358 family
HIMKHNBD_00233 3.2e-212 ftsW D Belongs to the SEDS family
HIMKHNBD_00234 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HIMKHNBD_00235 1.7e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HIMKHNBD_00236 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HIMKHNBD_00237 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HIMKHNBD_00238 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HIMKHNBD_00239 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HIMKHNBD_00240 1.9e-50 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HIMKHNBD_00241 2e-163 ctaG S cytochrome c oxidase
HIMKHNBD_00242 3.2e-59 ylbA S YugN-like family
HIMKHNBD_00243 2.2e-73 ylbB T COG0517 FOG CBS domain
HIMKHNBD_00244 2.3e-198 ylbC S protein with SCP PR1 domains
HIMKHNBD_00245 2.1e-54 ylbD S Putative coat protein
HIMKHNBD_00246 8.8e-37 ylbE S YlbE-like protein
HIMKHNBD_00247 1.2e-71 ylbF S Belongs to the UPF0342 family
HIMKHNBD_00248 5.5e-43 ylbG S UPF0298 protein
HIMKHNBD_00250 2.7e-97 rsmD 2.1.1.171 L Methyltransferase
HIMKHNBD_00251 2.8e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIMKHNBD_00252 2.2e-216 ylbJ S Sporulation integral membrane protein YlbJ
HIMKHNBD_00253 3.4e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HIMKHNBD_00254 4.7e-188 ylbL T Belongs to the peptidase S16 family
HIMKHNBD_00255 9.6e-228 ylbM S Belongs to the UPF0348 family
HIMKHNBD_00256 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
HIMKHNBD_00257 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HIMKHNBD_00258 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HIMKHNBD_00259 2e-88 ylbP K n-acetyltransferase
HIMKHNBD_00260 7.2e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIMKHNBD_00261 2.5e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HIMKHNBD_00262 1.2e-77 mraZ K Belongs to the MraZ family
HIMKHNBD_00263 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIMKHNBD_00264 2.9e-52 ftsL D Essential cell division protein
HIMKHNBD_00265 6.8e-41 ftsI 3.4.16.4 M Penicillin-binding Protein
HIMKHNBD_00266 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HIMKHNBD_00267 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HIMKHNBD_00268 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIMKHNBD_00269 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIMKHNBD_00270 8.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIMKHNBD_00271 2.2e-185 spoVE D Belongs to the SEDS family
HIMKHNBD_00272 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIMKHNBD_00273 1.8e-167 murB 1.3.1.98 M cell wall formation
HIMKHNBD_00274 6.2e-113 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HIMKHNBD_00275 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HIMKHNBD_00276 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIMKHNBD_00277 0.0 bpr O COG1404 Subtilisin-like serine proteases
HIMKHNBD_00278 2.7e-109 bpr O COG1404 Subtilisin-like serine proteases
HIMKHNBD_00279 2.4e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HIMKHNBD_00280 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMKHNBD_00281 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMKHNBD_00282 1.6e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HIMKHNBD_00283 4.7e-254 argE 3.5.1.16 E Acetylornithine deacetylase
HIMKHNBD_00284 2.2e-38 ylmC S sporulation protein
HIMKHNBD_00285 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HIMKHNBD_00286 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HIMKHNBD_00287 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIMKHNBD_00288 5.2e-41 yggT S membrane
HIMKHNBD_00289 6.1e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HIMKHNBD_00290 8.9e-68 divIVA D Cell division initiation protein
HIMKHNBD_00291 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIMKHNBD_00292 1.2e-61 dksA T COG1734 DnaK suppressor protein
HIMKHNBD_00293 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIMKHNBD_00294 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIMKHNBD_00295 1.9e-49 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIMKHNBD_00296 5.7e-232 pyrP F Xanthine uracil
HIMKHNBD_00297 4.5e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HIMKHNBD_00298 1.2e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIMKHNBD_00299 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIMKHNBD_00300 0.0 carB 6.3.5.5 F Belongs to the CarB family
HIMKHNBD_00301 1.2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HIMKHNBD_00302 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIMKHNBD_00303 6.1e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HIMKHNBD_00304 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIMKHNBD_00306 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HIMKHNBD_00307 1.1e-176 cysP P phosphate transporter
HIMKHNBD_00308 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HIMKHNBD_00309 3.2e-74 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HIMKHNBD_00310 2.2e-142 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HIMKHNBD_00311 9.9e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HIMKHNBD_00312 9.3e-78 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HIMKHNBD_00313 3.1e-46 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HIMKHNBD_00314 4.4e-250 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HIMKHNBD_00315 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HIMKHNBD_00316 2.2e-154 yloC S stress-induced protein
HIMKHNBD_00317 1.5e-40 ylzA S Belongs to the UPF0296 family
HIMKHNBD_00318 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HIMKHNBD_00319 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIMKHNBD_00320 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIMKHNBD_00321 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIMKHNBD_00322 4.6e-73 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIMKHNBD_00323 6.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIMKHNBD_00324 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIMKHNBD_00325 1e-170 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HIMKHNBD_00326 3.3e-138 stp 3.1.3.16 T phosphatase
HIMKHNBD_00327 3.3e-27 prkC 2.7.11.1 KLT serine threonine protein kinase
HIMKHNBD_00328 1.3e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
HIMKHNBD_00329 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HIMKHNBD_00330 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HIMKHNBD_00331 1.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
HIMKHNBD_00332 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HIMKHNBD_00333 5.5e-59 asp S protein conserved in bacteria
HIMKHNBD_00334 1.4e-303 yloV S kinase related to dihydroxyacetone kinase
HIMKHNBD_00335 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HIMKHNBD_00336 1.3e-154 sdaAA 4.3.1.17 E L-serine dehydratase
HIMKHNBD_00337 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIMKHNBD_00338 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HIMKHNBD_00339 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HIMKHNBD_00340 7.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HIMKHNBD_00341 4.6e-129 IQ reductase
HIMKHNBD_00342 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIMKHNBD_00343 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIMKHNBD_00344 1.2e-140 smc D Required for chromosome condensation and partitioning
HIMKHNBD_00345 0.0 smc D Required for chromosome condensation and partitioning
HIMKHNBD_00346 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIMKHNBD_00347 3e-139 S Phosphotransferase enzyme family
HIMKHNBD_00348 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HIMKHNBD_00349 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIMKHNBD_00350 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HIMKHNBD_00351 1.7e-35 ylqC S Belongs to the UPF0109 family
HIMKHNBD_00352 1.3e-61 ylqD S YlqD protein
HIMKHNBD_00353 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIMKHNBD_00354 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HIMKHNBD_00355 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIMKHNBD_00356 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIMKHNBD_00357 3.6e-100 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIMKHNBD_00358 7.8e-305 ylqG
HIMKHNBD_00359 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HIMKHNBD_00360 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HIMKHNBD_00361 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HIMKHNBD_00362 1.6e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HIMKHNBD_00363 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIMKHNBD_00364 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HIMKHNBD_00365 1.7e-156 xerC L tyrosine recombinase XerC
HIMKHNBD_00366 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HIMKHNBD_00367 4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HIMKHNBD_00368 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HIMKHNBD_00369 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HIMKHNBD_00370 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
HIMKHNBD_00371 2.5e-31 fliE N Flagellar hook-basal body
HIMKHNBD_00372 1.4e-263 fliF N The M ring may be actively involved in energy transduction
HIMKHNBD_00373 2.5e-156 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HIMKHNBD_00374 1.5e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HIMKHNBD_00375 4.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HIMKHNBD_00376 6.8e-60 fliJ N Flagellar biosynthesis chaperone
HIMKHNBD_00377 2.4e-46 ylxF S MgtE intracellular N domain
HIMKHNBD_00378 4.1e-29 fliK N Flagellar hook-length control protein
HIMKHNBD_00379 1.6e-165 fliK N Flagellar hook-length control protein
HIMKHNBD_00380 4.1e-72 flgD N Flagellar basal body rod modification protein
HIMKHNBD_00381 5.7e-138 flgG N Flagellar basal body rod
HIMKHNBD_00382 3.4e-32 flbD N protein, possibly involved in motility
HIMKHNBD_00383 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
HIMKHNBD_00384 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HIMKHNBD_00385 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HIMKHNBD_00386 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HIMKHNBD_00387 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
HIMKHNBD_00388 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
HIMKHNBD_00389 2e-37 fliQ N Role in flagellar biosynthesis
HIMKHNBD_00390 5.2e-131 fliR N Flagellar biosynthetic protein FliR
HIMKHNBD_00391 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HIMKHNBD_00392 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HIMKHNBD_00393 2.2e-191 flhF N Flagellar biosynthesis regulator FlhF
HIMKHNBD_00394 2.4e-156 flhG D Belongs to the ParA family
HIMKHNBD_00395 1.5e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HIMKHNBD_00396 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HIMKHNBD_00397 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
HIMKHNBD_00398 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HIMKHNBD_00399 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HIMKHNBD_00400 3.2e-59 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMKHNBD_00401 4.2e-28 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMKHNBD_00402 4e-49 ylxL
HIMKHNBD_00403 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HIMKHNBD_00404 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIMKHNBD_00405 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HIMKHNBD_00406 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIMKHNBD_00407 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIMKHNBD_00408 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
HIMKHNBD_00409 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HIMKHNBD_00410 1.5e-233 rasP M zinc metalloprotease
HIMKHNBD_00411 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIMKHNBD_00412 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIMKHNBD_00413 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
HIMKHNBD_00414 5.4e-206 nusA K Participates in both transcription termination and antitermination
HIMKHNBD_00415 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
HIMKHNBD_00416 1.8e-47 ylxQ J ribosomal protein
HIMKHNBD_00417 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIMKHNBD_00418 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIMKHNBD_00419 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIMKHNBD_00420 1.3e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIMKHNBD_00421 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIMKHNBD_00422 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIMKHNBD_00423 8.1e-67 yqhY S protein conserved in bacteria
HIMKHNBD_00424 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HIMKHNBD_00425 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HIMKHNBD_00426 5.5e-52 spoIIIAH S SpoIIIAH-like protein
HIMKHNBD_00427 1.1e-116 spoIIIAG S stage III sporulation protein AG
HIMKHNBD_00428 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HIMKHNBD_00429 6.3e-200 spoIIIAE S stage III sporulation protein AE
HIMKHNBD_00430 2.5e-41 spoIIIAD S Stage III sporulation protein AD
HIMKHNBD_00431 7.6e-29 spoIIIAC S stage III sporulation protein AC
HIMKHNBD_00432 1.6e-83 spoIIIAB S Stage III sporulation protein
HIMKHNBD_00433 1.6e-171 spoIIIAA S stage III sporulation protein AA
HIMKHNBD_00434 1.8e-36 yqhV S Protein of unknown function (DUF2619)
HIMKHNBD_00435 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIMKHNBD_00436 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HIMKHNBD_00437 7e-87 yqhR S Conserved membrane protein YqhR
HIMKHNBD_00438 8e-174 yqhQ S Protein of unknown function (DUF1385)
HIMKHNBD_00439 5.8e-62 yqhP
HIMKHNBD_00440 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
HIMKHNBD_00441 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HIMKHNBD_00442 1.3e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HIMKHNBD_00443 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
HIMKHNBD_00444 1.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HIMKHNBD_00445 2.3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HIMKHNBD_00446 3.3e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HIMKHNBD_00447 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HIMKHNBD_00448 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HIMKHNBD_00449 5.2e-23 sinI S Anti-repressor SinI
HIMKHNBD_00450 7.8e-55 sinR K transcriptional
HIMKHNBD_00451 1.6e-140 tasA S Cell division protein FtsN
HIMKHNBD_00452 4.6e-71 sipW 3.4.21.89 U Signal peptidase
HIMKHNBD_00453 3.6e-120 yqxM
HIMKHNBD_00454 1.1e-53 yqzG S Protein of unknown function (DUF3889)
HIMKHNBD_00455 2.3e-26 yqzE S YqzE-like protein
HIMKHNBD_00456 2.1e-61 S ComG operon protein 7
HIMKHNBD_00457 1.6e-64 comGF U Putative Competence protein ComGF
HIMKHNBD_00458 2.6e-20 comGE
HIMKHNBD_00459 4.5e-71 gspH NU Tfp pilus assembly protein FimT
HIMKHNBD_00460 8.9e-50 comGC U Required for transformation and DNA binding
HIMKHNBD_00461 4.6e-183 comGB NU COG1459 Type II secretory pathway, component PulF
HIMKHNBD_00462 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HIMKHNBD_00463 2.7e-185 corA P Mg2 transporter protein
HIMKHNBD_00464 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HIMKHNBD_00465 9.4e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIMKHNBD_00467 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
HIMKHNBD_00468 3.1e-37 yqgY S Protein of unknown function (DUF2626)
HIMKHNBD_00469 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HIMKHNBD_00470 5.4e-20 yqgW S Protein of unknown function (DUF2759)
HIMKHNBD_00471 6.9e-50 yqgV S Thiamine-binding protein
HIMKHNBD_00472 3.3e-197 yqgU
HIMKHNBD_00473 2e-216 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HIMKHNBD_00474 1.4e-178 glcK 2.7.1.2 G Glucokinase
HIMKHNBD_00475 8.5e-28 yqgQ S Protein conserved in bacteria
HIMKHNBD_00476 2.7e-231 nhaC C Na H antiporter
HIMKHNBD_00477 4e-07 yqgO
HIMKHNBD_00478 3e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIMKHNBD_00479 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HIMKHNBD_00480 1.2e-50 yqzD
HIMKHNBD_00481 1.6e-71 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HIMKHNBD_00482 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIMKHNBD_00483 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIMKHNBD_00484 2.9e-154 pstA P Phosphate transport system permease
HIMKHNBD_00485 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HIMKHNBD_00486 1.4e-156 pstS P Phosphate
HIMKHNBD_00487 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HIMKHNBD_00488 2.7e-65 yqgE EGP Major facilitator superfamily
HIMKHNBD_00489 4.6e-147 yqgE EGP Major facilitator superfamily
HIMKHNBD_00490 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HIMKHNBD_00491 2.9e-71 yqgC S protein conserved in bacteria
HIMKHNBD_00492 2.4e-128 yqgB S Protein of unknown function (DUF1189)
HIMKHNBD_00493 3.1e-47 yqfZ M LysM domain
HIMKHNBD_00494 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HIMKHNBD_00495 2.3e-52 yqfX S membrane
HIMKHNBD_00496 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HIMKHNBD_00497 2.9e-72 zur P Belongs to the Fur family
HIMKHNBD_00498 5.3e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HIMKHNBD_00499 4.6e-36 yqfT S Protein of unknown function (DUF2624)
HIMKHNBD_00500 2.8e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HIMKHNBD_00501 2.1e-225 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HIMKHNBD_00502 3.7e-43 yqfQ S YqfQ-like protein
HIMKHNBD_00503 1.7e-117 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HIMKHNBD_00504 3.6e-38 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HIMKHNBD_00505 4.8e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIMKHNBD_00506 3.8e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HIMKHNBD_00507 2.4e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
HIMKHNBD_00508 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIMKHNBD_00509 4.4e-261 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIMKHNBD_00510 4.5e-64 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIMKHNBD_00511 6.1e-88 yaiI S Belongs to the UPF0178 family
HIMKHNBD_00512 6.1e-117 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HIMKHNBD_00513 4.5e-112 ccpN K CBS domain
HIMKHNBD_00514 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HIMKHNBD_00515 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HIMKHNBD_00516 1.1e-109 recO L Involved in DNA repair and RecF pathway recombination
HIMKHNBD_00517 1.8e-16 S YqzL-like protein
HIMKHNBD_00518 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIMKHNBD_00519 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HIMKHNBD_00520 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HIMKHNBD_00521 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIMKHNBD_00522 0.0 yqfF S membrane-associated HD superfamily hydrolase
HIMKHNBD_00523 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
HIMKHNBD_00524 5.7e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HIMKHNBD_00525 9.3e-46 yqfC S sporulation protein YqfC
HIMKHNBD_00526 1.9e-42 yqfB
HIMKHNBD_00527 3.8e-118 yqfA S UPF0365 protein
HIMKHNBD_00528 5.7e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HIMKHNBD_00529 8e-68 yqeY S Yqey-like protein
HIMKHNBD_00530 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HIMKHNBD_00531 3.3e-156 yqeW P COG1283 Na phosphate symporter
HIMKHNBD_00532 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HIMKHNBD_00533 3.9e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HIMKHNBD_00534 6.6e-173 prmA J Methylates ribosomal protein L11
HIMKHNBD_00535 1.7e-87 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIMKHNBD_00536 2.5e-73 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIMKHNBD_00537 0.0 dnaK O Heat shock 70 kDa protein
HIMKHNBD_00538 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIMKHNBD_00539 1.4e-161 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIMKHNBD_00540 2.2e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
HIMKHNBD_00541 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIMKHNBD_00542 2.5e-53 yqxA S Protein of unknown function (DUF3679)
HIMKHNBD_00543 3.9e-218 spoIIP M stage II sporulation protein P
HIMKHNBD_00544 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HIMKHNBD_00545 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
HIMKHNBD_00546 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
HIMKHNBD_00547 0.0 comEC S Competence protein ComEC
HIMKHNBD_00548 8e-105 comEB 3.5.4.12 F ComE operon protein 2
HIMKHNBD_00549 6.2e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HIMKHNBD_00550 3.8e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIMKHNBD_00551 3.2e-138 yqeM Q Methyltransferase
HIMKHNBD_00552 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIMKHNBD_00553 1.6e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HIMKHNBD_00554 6.5e-93 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIMKHNBD_00555 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HIMKHNBD_00556 1.2e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HIMKHNBD_00557 2.2e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HIMKHNBD_00558 7.6e-94 yqeG S hydrolase of the HAD superfamily
HIMKHNBD_00560 2.5e-138 yqeF E GDSL-like Lipase/Acylhydrolase
HIMKHNBD_00561 2.9e-139 3.5.1.104 G Polysaccharide deacetylase
HIMKHNBD_00562 8e-106 yqeD S SNARE associated Golgi protein
HIMKHNBD_00563 8.9e-155 EGP Major facilitator Superfamily
HIMKHNBD_00564 1.1e-19 EGP Major facilitator Superfamily
HIMKHNBD_00565 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMKHNBD_00566 6e-157 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
HIMKHNBD_00567 3.6e-91 K Transcriptional regulator PadR-like family
HIMKHNBD_00568 1.2e-147 ydeE K AraC family transcriptional regulator
HIMKHNBD_00569 1.1e-95 adk 2.7.4.3 F adenylate kinase activity
HIMKHNBD_00570 2.3e-32 yyaR K acetyltransferase
HIMKHNBD_00571 5.3e-219 tetL EGP Major facilitator Superfamily
HIMKHNBD_00572 6.7e-82 yyaR K Acetyltransferase (GNAT) domain
HIMKHNBD_00573 1.5e-91 yrdA S DinB family
HIMKHNBD_00574 4.2e-144 S hydrolase
HIMKHNBD_00575 3.9e-145 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HIMKHNBD_00576 5.9e-129 glvR K Helix-turn-helix domain, rpiR family
HIMKHNBD_00577 2e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
HIMKHNBD_00578 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HIMKHNBD_00579 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HIMKHNBD_00580 2.1e-179 romA S Beta-lactamase superfamily domain
HIMKHNBD_00581 8.4e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIMKHNBD_00582 4.1e-164 yybE K Transcriptional regulator
HIMKHNBD_00583 3.2e-212 ynfM EGP Major facilitator Superfamily
HIMKHNBD_00584 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HIMKHNBD_00585 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HIMKHNBD_00586 7.1e-79 yrhH Q methyltransferase
HIMKHNBD_00588 8e-143 focA P Formate nitrite
HIMKHNBD_00589 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
HIMKHNBD_00590 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HIMKHNBD_00591 7e-81 yrhD S Protein of unknown function (DUF1641)
HIMKHNBD_00592 5.1e-34 yrhC S YrhC-like protein
HIMKHNBD_00593 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HIMKHNBD_00594 5.2e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HIMKHNBD_00595 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIMKHNBD_00596 2.3e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HIMKHNBD_00597 4.1e-27 yrzA S Protein of unknown function (DUF2536)
HIMKHNBD_00598 8.1e-70 yrrS S Protein of unknown function (DUF1510)
HIMKHNBD_00599 1.7e-60 pbpI 3.4.16.4 M Penicillin-binding Protein
HIMKHNBD_00600 6.5e-216 pbpI 3.4.16.4 M Penicillin-binding Protein
HIMKHNBD_00601 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIMKHNBD_00602 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HIMKHNBD_00603 6.1e-246 yegQ O COG0826 Collagenase and related proteases
HIMKHNBD_00604 2.9e-173 yegQ O Peptidase U32
HIMKHNBD_00605 2.3e-116 yrrM 2.1.1.104 S O-methyltransferase
HIMKHNBD_00606 4.1e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HIMKHNBD_00607 7.1e-46 yrzB S Belongs to the UPF0473 family
HIMKHNBD_00608 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIMKHNBD_00609 8.5e-41 yrzL S Belongs to the UPF0297 family
HIMKHNBD_00610 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIMKHNBD_00611 4.6e-162 yrrI S AI-2E family transporter
HIMKHNBD_00612 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HIMKHNBD_00613 2.9e-137 glnH ET Belongs to the bacterial solute-binding protein 3 family
HIMKHNBD_00614 3.4e-54 gluC P ABC transporter
HIMKHNBD_00615 9.5e-37 gluC P ABC transporter
HIMKHNBD_00616 2.9e-106 glnP P ABC transporter
HIMKHNBD_00617 2.1e-08 S Protein of unknown function (DUF3918)
HIMKHNBD_00618 2.9e-30 yrzR
HIMKHNBD_00619 3.4e-82 yrrD S protein conserved in bacteria
HIMKHNBD_00620 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HIMKHNBD_00621 1.7e-18 S COG0457 FOG TPR repeat
HIMKHNBD_00622 2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HIMKHNBD_00623 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
HIMKHNBD_00624 7.8e-64 cymR K Transcriptional regulator
HIMKHNBD_00625 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HIMKHNBD_00626 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HIMKHNBD_00627 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HIMKHNBD_00628 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HIMKHNBD_00631 9.7e-139 lytH 3.5.1.28 M COG3103 SH3 domain protein
HIMKHNBD_00632 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIMKHNBD_00633 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIMKHNBD_00634 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIMKHNBD_00635 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HIMKHNBD_00636 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
HIMKHNBD_00637 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HIMKHNBD_00638 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HIMKHNBD_00639 8.5e-50 yrzD S Post-transcriptional regulator
HIMKHNBD_00640 4.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMKHNBD_00641 9.5e-110 yrbG S membrane
HIMKHNBD_00642 2.4e-60 yrzE S Protein of unknown function (DUF3792)
HIMKHNBD_00643 2.5e-37 yajC U Preprotein translocase subunit YajC
HIMKHNBD_00644 3.3e-205 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HIMKHNBD_00645 7e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HIMKHNBD_00646 1.6e-20 yrzS S Protein of unknown function (DUF2905)
HIMKHNBD_00647 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIMKHNBD_00648 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIMKHNBD_00649 4.9e-45 bofC S BofC C-terminal domain
HIMKHNBD_00650 5.5e-40 bofC S BofC C-terminal domain
HIMKHNBD_00652 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIMKHNBD_00653 2.6e-113 safA M spore coat assembly protein SafA
HIMKHNBD_00654 3.8e-167 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HIMKHNBD_00655 3.5e-32 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HIMKHNBD_00656 3.2e-150 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HIMKHNBD_00657 3.3e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HIMKHNBD_00658 3.3e-222 nifS 2.8.1.7 E Cysteine desulfurase
HIMKHNBD_00659 3e-93 niaR S small molecule binding protein (contains 3H domain)
HIMKHNBD_00660 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
HIMKHNBD_00661 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HIMKHNBD_00662 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIMKHNBD_00663 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HIMKHNBD_00664 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HIMKHNBD_00665 3.2e-56 ysxB J ribosomal protein
HIMKHNBD_00666 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HIMKHNBD_00667 7.8e-160 spoIVFB S Stage IV sporulation protein
HIMKHNBD_00668 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HIMKHNBD_00669 2.3e-142 minD D Belongs to the ParA family
HIMKHNBD_00670 3.2e-92 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HIMKHNBD_00671 5.4e-84 mreD M shape-determining protein
HIMKHNBD_00672 1e-156 mreC M Involved in formation and maintenance of cell shape
HIMKHNBD_00673 4e-184 mreB D Rod shape-determining protein MreB
HIMKHNBD_00674 2e-126 radC E Belongs to the UPF0758 family
HIMKHNBD_00675 1.9e-98 maf D septum formation protein Maf
HIMKHNBD_00676 3e-91 spoIIB S Sporulation related domain
HIMKHNBD_00677 1.1e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HIMKHNBD_00678 2.4e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HIMKHNBD_00679 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIMKHNBD_00680 2.1e-25
HIMKHNBD_00681 3.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HIMKHNBD_00682 2.6e-226 spoVID M stage VI sporulation protein D
HIMKHNBD_00683 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HIMKHNBD_00684 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
HIMKHNBD_00685 1.6e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HIMKHNBD_00686 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HIMKHNBD_00687 6.8e-145 hemX O cytochrome C
HIMKHNBD_00688 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HIMKHNBD_00689 3.8e-87 ysxD
HIMKHNBD_00690 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
HIMKHNBD_00691 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HIMKHNBD_00692 3e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HIMKHNBD_00693 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIMKHNBD_00694 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIMKHNBD_00695 2.3e-187 ysoA H Tetratricopeptide repeat
HIMKHNBD_00696 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HIMKHNBD_00697 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HIMKHNBD_00698 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HIMKHNBD_00699 6.7e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HIMKHNBD_00700 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HIMKHNBD_00701 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
HIMKHNBD_00702 1.4e-112 ilvB 2.2.1.6 E Acetolactate synthase
HIMKHNBD_00703 2.7e-160 ilvB 2.2.1.6 E Acetolactate synthase
HIMKHNBD_00706 9.2e-40 yrkD S protein conserved in bacteria
HIMKHNBD_00707 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
HIMKHNBD_00708 5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
HIMKHNBD_00709 1e-199 yrkH P Rhodanese Homology Domain
HIMKHNBD_00710 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
HIMKHNBD_00711 7.3e-117 yrkJ S membrane transporter protein
HIMKHNBD_00712 4.9e-117 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HIMKHNBD_00713 4.1e-101 S Protein of unknown function (DUF2812)
HIMKHNBD_00714 4.1e-50 K Transcriptional regulator PadR-like family
HIMKHNBD_00715 2.3e-181 S Patatin-like phospholipase
HIMKHNBD_00716 5.5e-83 S DinB superfamily
HIMKHNBD_00717 5.6e-116 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HIMKHNBD_00718 2.7e-67 K COG1802 Transcriptional regulators
HIMKHNBD_00719 3.9e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
HIMKHNBD_00720 2.2e-142 sdaC E Serine transporter
HIMKHNBD_00721 9.1e-164 E Peptidase dimerisation domain
HIMKHNBD_00722 7.6e-126 rhaS5 K helix_turn_helix, arabinose operon control protein
HIMKHNBD_00723 1.5e-175 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HIMKHNBD_00724 6.5e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIMKHNBD_00725 7.5e-191 ydeG EGP Major facilitator superfamily
HIMKHNBD_00726 3.5e-28 3.6.1.55 F Belongs to the Nudix hydrolase family
HIMKHNBD_00729 4.3e-266 ygaK C COG0277 FAD FMN-containing dehydrogenases
HIMKHNBD_00730 1.2e-09 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMKHNBD_00731 8.4e-168 czcD P COG1230 Co Zn Cd efflux system component
HIMKHNBD_00732 6.8e-195 trkA P Oxidoreductase
HIMKHNBD_00735 1.8e-14 ykkA S Protein of unknown function (DUF664)
HIMKHNBD_00736 3.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
HIMKHNBD_00738 6.9e-195 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HIMKHNBD_00739 2.6e-51 ydeH
HIMKHNBD_00740 2.3e-165 S Sodium Bile acid symporter family
HIMKHNBD_00741 3.8e-201 adhA 1.1.1.1 C alcohol dehydrogenase
HIMKHNBD_00742 3.6e-67 yraB K helix_turn_helix, mercury resistance
HIMKHNBD_00743 1.1e-223 mleN_2 C antiporter
HIMKHNBD_00744 4.4e-258 K helix_turn_helix gluconate operon transcriptional repressor
HIMKHNBD_00745 7.9e-114 paiB K Transcriptional regulator
HIMKHNBD_00747 9.6e-177 ydeR EGP Major facilitator Superfamily
HIMKHNBD_00748 1.2e-100 ydeS K Transcriptional regulator
HIMKHNBD_00749 1.4e-47 yraD M Spore coat protein
HIMKHNBD_00750 3.1e-24 yraE
HIMKHNBD_00751 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HIMKHNBD_00752 8.4e-63 yraF M Spore coat protein
HIMKHNBD_00753 1.3e-35 yraG
HIMKHNBD_00754 2.1e-214 ydfH 2.7.13.3 T Histidine kinase
HIMKHNBD_00755 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMKHNBD_00756 0.0 ydfJ S drug exporters of the RND superfamily
HIMKHNBD_00757 1.8e-133 puuD S Peptidase C26
HIMKHNBD_00758 6.7e-298 expZ S ABC transporter
HIMKHNBD_00759 5.7e-97 ynaD J Acetyltransferase (GNAT) domain
HIMKHNBD_00760 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
HIMKHNBD_00761 2.4e-29 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HIMKHNBD_00762 4.1e-156 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HIMKHNBD_00763 3.9e-210 tcaB EGP Major facilitator Superfamily
HIMKHNBD_00764 1.1e-223 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIMKHNBD_00765 1.9e-155 K Helix-turn-helix XRE-family like proteins
HIMKHNBD_00766 9.4e-122 ydhB S membrane transporter protein
HIMKHNBD_00767 2.2e-81 bltD 2.3.1.57 K FR47-like protein
HIMKHNBD_00768 3.4e-149 bltR K helix_turn_helix, mercury resistance
HIMKHNBD_00769 3.4e-147 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HIMKHNBD_00770 8.1e-111 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HIMKHNBD_00771 1.3e-94 ycgJ_1 Q ubiE/COQ5 methyltransferase family
HIMKHNBD_00772 1.8e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
HIMKHNBD_00773 6.9e-119 ydhC K FCD
HIMKHNBD_00774 4.6e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HIMKHNBD_00777 2.1e-260 pbpE V Beta-lactamase
HIMKHNBD_00779 5.5e-98 ydhK M Protein of unknown function (DUF1541)
HIMKHNBD_00780 2e-195 pbuE EGP Major facilitator Superfamily
HIMKHNBD_00781 1.5e-132 ydhQ K UTRA
HIMKHNBD_00782 9.9e-118 K FCD
HIMKHNBD_00783 8.2e-216 yeaN P COG2807 Cyanate permease
HIMKHNBD_00784 5.1e-21 sugE P Small Multidrug Resistance protein
HIMKHNBD_00785 2.3e-51 ykkC P Small Multidrug Resistance protein
HIMKHNBD_00786 2.9e-102 yvdT K Transcriptional regulator
HIMKHNBD_00787 1e-268 yveA E amino acid
HIMKHNBD_00788 5.6e-149 ydhU P Catalase
HIMKHNBD_00789 7.3e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HIMKHNBD_00790 1.5e-183 yhfP 1.1.1.1 C Quinone oxidoreductase
HIMKHNBD_00791 2.4e-251 iolT EGP Major facilitator Superfamily
HIMKHNBD_00794 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMKHNBD_00795 7.8e-08
HIMKHNBD_00797 1.3e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HIMKHNBD_00798 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HIMKHNBD_00799 5.5e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HIMKHNBD_00800 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HIMKHNBD_00801 2.8e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIMKHNBD_00802 0.0 ydiF S ABC transporter
HIMKHNBD_00803 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HIMKHNBD_00804 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HIMKHNBD_00805 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HIMKHNBD_00806 1.8e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HIMKHNBD_00807 1.7e-27 ydiK S Domain of unknown function (DUF4305)
HIMKHNBD_00808 4.3e-127 ydiL S CAAX protease self-immunity
HIMKHNBD_00809 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIMKHNBD_00810 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIMKHNBD_00811 1.5e-24 S Protein of unknown function (DUF4064)
HIMKHNBD_00812 0.0 K NB-ARC domain
HIMKHNBD_00813 8e-199 gutB 1.1.1.14 E Dehydrogenase
HIMKHNBD_00814 7.1e-248 gutA G MFS/sugar transport protein
HIMKHNBD_00815 1.3e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HIMKHNBD_00816 3.6e-30 yjdJ S Domain of unknown function (DUF4306)
HIMKHNBD_00817 1.3e-112 pspA KT Phage shock protein A
HIMKHNBD_00818 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIMKHNBD_00819 2.9e-118 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HIMKHNBD_00820 1.8e-144 ydjI S virion core protein (lumpy skin disease virus)
HIMKHNBD_00821 0.0 yrhL I Acyltransferase family
HIMKHNBD_00822 1.4e-145 rsiV S Protein of unknown function (DUF3298)
HIMKHNBD_00823 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HIMKHNBD_00824 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HIMKHNBD_00825 1.2e-61 ydjM M Lytic transglycolase
HIMKHNBD_00826 2.3e-134 ydjN U Involved in the tonB-independent uptake of proteins
HIMKHNBD_00828 7.2e-35 ydjO S Cold-inducible protein YdjO
HIMKHNBD_00829 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HIMKHNBD_00830 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HIMKHNBD_00831 3.2e-133 yeaC S COG0714 MoxR-like ATPases
HIMKHNBD_00832 1.2e-29 yeaC S COG0714 MoxR-like ATPases
HIMKHNBD_00833 3.3e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HIMKHNBD_00834 0.0 yebA E COG1305 Transglutaminase-like enzymes
HIMKHNBD_00835 4.8e-81 yebA E COG1305 Transglutaminase-like enzymes
HIMKHNBD_00836 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HIMKHNBD_00837 5e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HIMKHNBD_00838 5.1e-249 S Domain of unknown function (DUF4179)
HIMKHNBD_00839 8.1e-209 pbuG S permease
HIMKHNBD_00840 1.5e-125 yebC M Membrane
HIMKHNBD_00842 7.5e-92 yebE S UPF0316 protein
HIMKHNBD_00843 5.5e-29 yebG S NETI protein
HIMKHNBD_00844 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HIMKHNBD_00845 1.8e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIMKHNBD_00846 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIMKHNBD_00847 3.8e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HIMKHNBD_00848 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIMKHNBD_00849 7.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIMKHNBD_00850 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIMKHNBD_00851 4.4e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HIMKHNBD_00852 1.9e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HIMKHNBD_00853 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HIMKHNBD_00854 6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HIMKHNBD_00855 4.5e-233 purD 6.3.4.13 F Belongs to the GARS family
HIMKHNBD_00856 2.6e-25 S Protein of unknown function (DUF2892)
HIMKHNBD_00857 9.7e-74 yerA 3.5.4.2 F adenine deaminase
HIMKHNBD_00858 1.3e-259 yerA 3.5.4.2 F adenine deaminase
HIMKHNBD_00859 1.5e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
HIMKHNBD_00860 2.4e-50 yerC S protein conserved in bacteria
HIMKHNBD_00861 4.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HIMKHNBD_00862 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HIMKHNBD_00863 2.4e-270 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HIMKHNBD_00864 8.4e-131 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HIMKHNBD_00865 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIMKHNBD_00866 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
HIMKHNBD_00867 6.8e-192 yerI S homoserine kinase type II (protein kinase fold)
HIMKHNBD_00868 1.3e-120 sapB S MgtC SapB transporter
HIMKHNBD_00869 1.4e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMKHNBD_00870 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIMKHNBD_00871 1.4e-100 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIMKHNBD_00872 6e-157 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIMKHNBD_00873 3.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIMKHNBD_00874 4.2e-150 yerO K Transcriptional regulator
HIMKHNBD_00875 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HIMKHNBD_00876 5.3e-60 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HIMKHNBD_00877 4.8e-96 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HIMKHNBD_00879 2.6e-124 yokA L Recombinase
HIMKHNBD_00880 4.6e-64 yokA L Recombinase
HIMKHNBD_00881 6.8e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
HIMKHNBD_00882 4.7e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HIMKHNBD_00883 2.8e-90 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIMKHNBD_00884 1.4e-66 ypoP K transcriptional
HIMKHNBD_00885 6.1e-97 ypmS S protein conserved in bacteria
HIMKHNBD_00886 2.5e-89 ypmR E GDSL-like Lipase/Acylhydrolase
HIMKHNBD_00887 1.8e-33 ypmR E GDSL-like Lipase/Acylhydrolase
HIMKHNBD_00888 5.1e-113 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HIMKHNBD_00889 3.2e-37 ypmP S Protein of unknown function (DUF2535)
HIMKHNBD_00890 3.7e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HIMKHNBD_00891 8.3e-174 pspF K Transcriptional regulator
HIMKHNBD_00892 1.6e-109 hlyIII S protein, Hemolysin III
HIMKHNBD_00893 6.1e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HIMKHNBD_00894 4.8e-69 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIMKHNBD_00896 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIMKHNBD_00897 8.5e-113 ypjP S YpjP-like protein
HIMKHNBD_00898 5.7e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HIMKHNBD_00899 1e-75 yphP S Belongs to the UPF0403 family
HIMKHNBD_00900 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HIMKHNBD_00901 2.2e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
HIMKHNBD_00902 3.1e-99 ypgQ S phosphohydrolase
HIMKHNBD_00903 1e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HIMKHNBD_00904 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HIMKHNBD_00905 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HIMKHNBD_00906 1e-30 cspD K Cold-shock protein
HIMKHNBD_00907 1.3e-11 degR
HIMKHNBD_00908 1.2e-36 S Protein of unknown function (DUF2564)
HIMKHNBD_00909 1.5e-28 ypeQ S Zinc-finger
HIMKHNBD_00910 9.1e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HIMKHNBD_00911 2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HIMKHNBD_00912 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
HIMKHNBD_00914 3.5e-163 polA 2.7.7.7 L 5'3' exonuclease
HIMKHNBD_00916 2.2e-38 ypbS S Protein of unknown function (DUF2533)
HIMKHNBD_00917 0.0 ypbR S Dynamin family
HIMKHNBD_00918 1.9e-89 ypbQ S protein conserved in bacteria
HIMKHNBD_00919 6.1e-202 bcsA Q Naringenin-chalcone synthase
HIMKHNBD_00920 1.3e-105 J Acetyltransferase (GNAT) domain
HIMKHNBD_00921 5.8e-39 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HIMKHNBD_00923 3.9e-22 ydfR S Protein of unknown function (DUF421)
HIMKHNBD_00924 1.3e-32 ydfR S Protein of unknown function (DUF421)
HIMKHNBD_00925 1.9e-98 yrdC 3.5.1.19 Q Isochorismatase family
HIMKHNBD_00927 2.2e-235 pbuX F xanthine
HIMKHNBD_00928 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIMKHNBD_00929 1.3e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HIMKHNBD_00930 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HIMKHNBD_00932 6.6e-22 S YpzG-like protein
HIMKHNBD_00933 7.9e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HIMKHNBD_00934 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HIMKHNBD_00935 1.1e-98 ypsA S Belongs to the UPF0398 family
HIMKHNBD_00936 9.9e-33 cotD S Inner spore coat protein D
HIMKHNBD_00938 7.3e-212 yprB L RNase_H superfamily
HIMKHNBD_00939 4.2e-222 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HIMKHNBD_00940 1.5e-23 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HIMKHNBD_00941 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HIMKHNBD_00942 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
HIMKHNBD_00943 2.1e-49 yppG S YppG-like protein
HIMKHNBD_00945 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
HIMKHNBD_00948 2.6e-188 yppC S Protein of unknown function (DUF2515)
HIMKHNBD_00949 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HIMKHNBD_00950 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HIMKHNBD_00951 5.7e-91 ypoC
HIMKHNBD_00952 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIMKHNBD_00953 3e-130 dnaD L DNA replication protein DnaD
HIMKHNBD_00954 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HIMKHNBD_00955 3.7e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HIMKHNBD_00956 1.5e-80 ypmB S protein conserved in bacteria
HIMKHNBD_00957 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HIMKHNBD_00958 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HIMKHNBD_00959 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HIMKHNBD_00960 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HIMKHNBD_00961 1.7e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HIMKHNBD_00962 6.2e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HIMKHNBD_00963 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HIMKHNBD_00964 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HIMKHNBD_00965 1.9e-132 bshB1 S proteins, LmbE homologs
HIMKHNBD_00966 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HIMKHNBD_00967 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIMKHNBD_00968 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HIMKHNBD_00969 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HIMKHNBD_00970 3.8e-226 oxdC 4.1.1.2 G Oxalate decarboxylase
HIMKHNBD_00971 9.5e-141 ypjB S sporulation protein
HIMKHNBD_00972 3.2e-104 ypjA S membrane
HIMKHNBD_00973 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HIMKHNBD_00974 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HIMKHNBD_00975 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HIMKHNBD_00976 3.2e-77 ypiF S Protein of unknown function (DUF2487)
HIMKHNBD_00977 2.1e-99 ypiB S Belongs to the UPF0302 family
HIMKHNBD_00978 9.1e-234 S COG0457 FOG TPR repeat
HIMKHNBD_00979 8.1e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HIMKHNBD_00980 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HIMKHNBD_00981 1.9e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HIMKHNBD_00982 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HIMKHNBD_00983 5.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HIMKHNBD_00984 7.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HIMKHNBD_00985 1.5e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HIMKHNBD_00986 2.4e-152 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HIMKHNBD_00987 4.6e-288 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HIMKHNBD_00988 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HIMKHNBD_00989 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HIMKHNBD_00990 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HIMKHNBD_00991 3e-139 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HIMKHNBD_00992 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HIMKHNBD_00993 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIMKHNBD_00994 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HIMKHNBD_00995 1.4e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HIMKHNBD_00996 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HIMKHNBD_00997 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
HIMKHNBD_00998 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIMKHNBD_00999 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HIMKHNBD_01000 1.1e-133 yphF
HIMKHNBD_01001 3.3e-16 yphE S Protein of unknown function (DUF2768)
HIMKHNBD_01002 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HIMKHNBD_01003 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HIMKHNBD_01004 7.2e-104 yphA
HIMKHNBD_01005 4.7e-08 S YpzI-like protein
HIMKHNBD_01006 1.7e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HIMKHNBD_01007 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HIMKHNBD_01008 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HIMKHNBD_01009 1.4e-12 S Family of unknown function (DUF5359)
HIMKHNBD_01010 1.4e-60 ypfA M Flagellar protein YcgR
HIMKHNBD_01011 1e-251 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HIMKHNBD_01012 3e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HIMKHNBD_01013 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
HIMKHNBD_01014 3.4e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HIMKHNBD_01015 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HIMKHNBD_01016 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HIMKHNBD_01017 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
HIMKHNBD_01018 1.7e-84 ypbF S Protein of unknown function (DUF2663)
HIMKHNBD_01019 5.5e-34 ypbE M Lysin motif
HIMKHNBD_01020 1.7e-42 ypbE M Lysin motif
HIMKHNBD_01021 4e-99 ypbD S metal-dependent membrane protease
HIMKHNBD_01022 8.8e-270 recQ 3.6.4.12 L DNA helicase
HIMKHNBD_01023 3.2e-192 ypbB 5.1.3.1 S protein conserved in bacteria
HIMKHNBD_01024 3.6e-41 fer C Ferredoxin
HIMKHNBD_01025 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIMKHNBD_01026 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMKHNBD_01027 5.7e-192 rsiX
HIMKHNBD_01028 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HIMKHNBD_01029 0.0 resE 2.7.13.3 T Histidine kinase
HIMKHNBD_01030 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMKHNBD_01031 2.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HIMKHNBD_01032 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HIMKHNBD_01033 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HIMKHNBD_01034 1.3e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HIMKHNBD_01035 1.3e-88 spmB S Spore maturation protein
HIMKHNBD_01036 2e-103 spmA S Spore maturation protein
HIMKHNBD_01037 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HIMKHNBD_01038 3.3e-92 ypuI S Protein of unknown function (DUF3907)
HIMKHNBD_01039 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIMKHNBD_01040 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIMKHNBD_01042 7.8e-92 ypuF S Domain of unknown function (DUF309)
HIMKHNBD_01043 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMKHNBD_01044 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HIMKHNBD_01045 3.2e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HIMKHNBD_01046 1.1e-110 ribE 2.5.1.9 H Riboflavin synthase
HIMKHNBD_01047 3.1e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HIMKHNBD_01048 6.4e-49 ypuD
HIMKHNBD_01049 6.5e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HIMKHNBD_01050 9.1e-81 ccdC1 O Protein of unknown function (DUF1453)
HIMKHNBD_01051 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIMKHNBD_01052 1.9e-153 ypuA S Secreted protein
HIMKHNBD_01053 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIMKHNBD_01054 3.2e-270 spoVAF EG Stage V sporulation protein AF
HIMKHNBD_01055 5.2e-110 spoVAEA S stage V sporulation protein
HIMKHNBD_01056 8.5e-57 spoVAEB S stage V sporulation protein
HIMKHNBD_01057 1.2e-188 spoVAD I Stage V sporulation protein AD
HIMKHNBD_01058 6e-79 spoVAC S stage V sporulation protein AC
HIMKHNBD_01059 4.5e-68 spoVAB S Stage V sporulation protein AB
HIMKHNBD_01060 4.8e-111 spoVAA S Stage V sporulation protein AA
HIMKHNBD_01061 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMKHNBD_01062 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HIMKHNBD_01063 1.1e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HIMKHNBD_01064 2.6e-29 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HIMKHNBD_01065 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
HIMKHNBD_01066 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HIMKHNBD_01067 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HIMKHNBD_01068 8e-81
HIMKHNBD_01069 6.4e-93 ywhD S YwhD family
HIMKHNBD_01070 1.2e-117 ywhC S Peptidase family M50
HIMKHNBD_01071 3.9e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HIMKHNBD_01072 4.9e-67 ywhA K Transcriptional regulator
HIMKHNBD_01073 1.9e-245 yhdG_1 E C-terminus of AA_permease
HIMKHNBD_01074 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
HIMKHNBD_01075 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HIMKHNBD_01076 6.9e-36 ywzC S Belongs to the UPF0741 family
HIMKHNBD_01077 6.6e-110 rsfA_1
HIMKHNBD_01078 9.7e-52 padR K PadR family transcriptional regulator
HIMKHNBD_01079 1.2e-92 S membrane
HIMKHNBD_01080 2.1e-40 V ABC transporter, ATP-binding protein
HIMKHNBD_01081 1.5e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HIMKHNBD_01082 4.5e-149 cysL K Transcriptional regulator
HIMKHNBD_01083 1.3e-158 MA20_14895 S Conserved hypothetical protein 698
HIMKHNBD_01084 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HIMKHNBD_01085 1.1e-146 ywfI C May function as heme-dependent peroxidase
HIMKHNBD_01086 5.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
HIMKHNBD_01087 1.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
HIMKHNBD_01088 1.4e-207 bacE EGP Major facilitator Superfamily
HIMKHNBD_01089 7e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HIMKHNBD_01090 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMKHNBD_01091 3.4e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HIMKHNBD_01092 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HIMKHNBD_01093 3.5e-222 ywfA EGP Major facilitator Superfamily
HIMKHNBD_01094 1.1e-204 tcaB EGP Major facilitator Superfamily
HIMKHNBD_01095 1.2e-258 lysP E amino acid
HIMKHNBD_01096 0.0 rocB E arginine degradation protein
HIMKHNBD_01097 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HIMKHNBD_01098 8.2e-213 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HIMKHNBD_01099 2.4e-59
HIMKHNBD_01100 3e-86 spsL 5.1.3.13 M Spore Coat
HIMKHNBD_01101 4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HIMKHNBD_01102 6.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIMKHNBD_01103 1.2e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HIMKHNBD_01104 3.3e-178 spsG M Spore Coat
HIMKHNBD_01105 2.6e-132 spsF M Spore Coat
HIMKHNBD_01106 2.4e-214 spsE 2.5.1.56 M acid synthase
HIMKHNBD_01107 5.2e-156 spsD 2.3.1.210 K Spore Coat
HIMKHNBD_01108 4e-220 spsC E Belongs to the DegT DnrJ EryC1 family
HIMKHNBD_01109 1.8e-136 spsB M Capsule polysaccharide biosynthesis protein
HIMKHNBD_01110 4.9e-120 spsB M Capsule polysaccharide biosynthesis protein
HIMKHNBD_01111 1.3e-142 spsA M Spore Coat
HIMKHNBD_01112 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HIMKHNBD_01113 4.2e-46 ywdK S small membrane protein
HIMKHNBD_01114 2e-228 ywdJ F Xanthine uracil
HIMKHNBD_01115 4.7e-41 ywdI S Family of unknown function (DUF5327)
HIMKHNBD_01116 1.2e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIMKHNBD_01117 1.5e-149 ywdF GT2,GT4 S Glycosyltransferase like family 2
HIMKHNBD_01119 5.8e-88 ywdD
HIMKHNBD_01120 6.3e-57 pex K Transcriptional regulator PadR-like family
HIMKHNBD_01121 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIMKHNBD_01122 7.4e-20 ywdA
HIMKHNBD_01123 4.1e-283 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
HIMKHNBD_01124 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMKHNBD_01125 2.8e-151 sacT K transcriptional antiterminator
HIMKHNBD_01127 0.0 vpr O Belongs to the peptidase S8 family
HIMKHNBD_01128 4.4e-183 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMKHNBD_01129 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HIMKHNBD_01130 9.8e-214 rodA D Belongs to the SEDS family
HIMKHNBD_01131 1.7e-76 ysnE K acetyltransferase
HIMKHNBD_01132 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
HIMKHNBD_01133 9.9e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HIMKHNBD_01134 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HIMKHNBD_01135 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HIMKHNBD_01136 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HIMKHNBD_01137 8.4e-27 ywzA S membrane
HIMKHNBD_01138 3.9e-295 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HIMKHNBD_01139 5.1e-61 gtcA S GtrA-like protein
HIMKHNBD_01140 3.9e-75 ywcC K Bacterial regulatory proteins, tetR family
HIMKHNBD_01142 2.1e-128 H Methionine biosynthesis protein MetW
HIMKHNBD_01143 1.2e-131 S Streptomycin biosynthesis protein StrF
HIMKHNBD_01144 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HIMKHNBD_01145 1.4e-242 ywbN P Dyp-type peroxidase family protein
HIMKHNBD_01146 8.2e-25 ycdO P iron ion transport
HIMKHNBD_01147 5.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HIMKHNBD_01148 7.4e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HIMKHNBD_01149 8.2e-152 ywbI K Transcriptional regulator
HIMKHNBD_01150 4.2e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HIMKHNBD_01151 1.7e-109 ywbG M effector of murein hydrolase
HIMKHNBD_01152 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HIMKHNBD_01153 2.6e-135 mta K transcriptional
HIMKHNBD_01154 3e-223 ywbD 2.1.1.191 J Methyltransferase
HIMKHNBD_01155 2.9e-66 ywbC 4.4.1.5 E glyoxalase
HIMKHNBD_01156 7.1e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMKHNBD_01157 9.3e-250 epr 3.4.21.62 O Belongs to the peptidase S8 family
HIMKHNBD_01158 4.1e-161 gspA M General stress
HIMKHNBD_01159 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HIMKHNBD_01160 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HIMKHNBD_01161 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
HIMKHNBD_01162 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_01163 4.8e-229 dltB M membrane protein involved in D-alanine export
HIMKHNBD_01164 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_01165 4.5e-227 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIMKHNBD_01166 1.9e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HIMKHNBD_01167 4.6e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HIMKHNBD_01168 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HIMKHNBD_01169 2.8e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMKHNBD_01170 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HIMKHNBD_01171 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HIMKHNBD_01172 3.5e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HIMKHNBD_01173 4.7e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMKHNBD_01174 1e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMKHNBD_01175 1.5e-166 cbrA3 P Periplasmic binding protein
HIMKHNBD_01176 1.7e-57 arsR K transcriptional
HIMKHNBD_01177 4.2e-226 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HIMKHNBD_01178 1.3e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HIMKHNBD_01179 2.3e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HIMKHNBD_01180 1.6e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMKHNBD_01181 6.2e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIMKHNBD_01182 4e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HIMKHNBD_01183 1.8e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
HIMKHNBD_01184 2.1e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HIMKHNBD_01185 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HIMKHNBD_01186 2.5e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HIMKHNBD_01187 7.9e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HIMKHNBD_01188 6.5e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIMKHNBD_01189 1e-291 cydD V ATP-binding protein
HIMKHNBD_01190 2.4e-311 cydD V ATP-binding
HIMKHNBD_01191 2.5e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HIMKHNBD_01192 4.5e-266 cydA 1.10.3.14 C oxidase, subunit
HIMKHNBD_01193 1e-214 cimH C COG3493 Na citrate symporter
HIMKHNBD_01194 7.3e-155 yxkH G Polysaccharide deacetylase
HIMKHNBD_01195 2.6e-205 msmK P Belongs to the ABC transporter superfamily
HIMKHNBD_01196 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HIMKHNBD_01197 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIMKHNBD_01198 3.8e-87 yxkC S Domain of unknown function (DUF4352)
HIMKHNBD_01199 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HIMKHNBD_01200 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HIMKHNBD_01203 2e-85 yxjI S LURP-one-related
HIMKHNBD_01204 4.1e-217 yxjG 2.1.1.14 E Methionine synthase
HIMKHNBD_01205 2.6e-155 rlmA 2.1.1.187 Q Methyltransferase domain
HIMKHNBD_01206 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIMKHNBD_01207 1.8e-71 T Domain of unknown function (DUF4163)
HIMKHNBD_01208 4.3e-49 yxiS
HIMKHNBD_01209 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HIMKHNBD_01210 1.4e-221 citH C Citrate transporter
HIMKHNBD_01211 2e-140 exoK GH16 M licheninase activity
HIMKHNBD_01213 2.2e-103 licT K transcriptional antiterminator
HIMKHNBD_01214 9.2e-21 licT K transcriptional antiterminator
HIMKHNBD_01215 5.1e-221 yxiO S COG2270 Permeases of the major facilitator superfamily
HIMKHNBD_01216 2.1e-239 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HIMKHNBD_01219 1.2e-61 S SMI1-KNR4 cell-wall
HIMKHNBD_01220 7e-49 yxiI S Protein of unknown function (DUF2716)
HIMKHNBD_01221 3e-20
HIMKHNBD_01222 3.8e-15 S YxiJ-like protein
HIMKHNBD_01223 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HIMKHNBD_01224 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
HIMKHNBD_01225 1e-57 ansR K Transcriptional regulator
HIMKHNBD_01226 4e-220 yqxK 3.6.4.12 L DNA helicase
HIMKHNBD_01227 7.5e-89 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HIMKHNBD_01229 6.3e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HIMKHNBD_01231 9e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HIMKHNBD_01232 3.2e-39 yqkC S Protein of unknown function (DUF2552)
HIMKHNBD_01233 7.7e-61 yqkB S Belongs to the HesB IscA family
HIMKHNBD_01234 2.6e-172 yqkA K GrpB protein
HIMKHNBD_01235 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HIMKHNBD_01236 8.7e-89 yqjY K acetyltransferase
HIMKHNBD_01237 5.7e-142 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIMKHNBD_01238 1.4e-56 S YolD-like protein
HIMKHNBD_01240 1.3e-185 yueF S transporter activity
HIMKHNBD_01242 1.6e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMKHNBD_01243 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HIMKHNBD_01244 7.4e-250 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HIMKHNBD_01245 4e-139 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMKHNBD_01246 1e-173 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HIMKHNBD_01247 1.2e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIMKHNBD_01248 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HIMKHNBD_01249 1.7e-238 pksG 2.3.3.10 I synthase
HIMKHNBD_01250 3.4e-219 eryK 1.14.13.154 C Cytochrome P450
HIMKHNBD_01251 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HIMKHNBD_01252 0.0 Q Polyketide synthase of type I
HIMKHNBD_01253 0.0 Q Polyketide synthase of type I
HIMKHNBD_01254 0.0 pfaA Q Polyketide synthase of type I
HIMKHNBD_01255 0.0 pksJ Q Polyketide synthase of type I
HIMKHNBD_01256 0.0 pksJ Q Polyketide synthase of type I
HIMKHNBD_01257 3.5e-88 pksJ Q Polyketide synthase of type I
HIMKHNBD_01258 0.0 pksJ Q Polyketide synthase of type I
HIMKHNBD_01259 0.0 Q Polyketide synthase of type I
HIMKHNBD_01260 0.0 1.1.1.320 Q Polyketide synthase of type I
HIMKHNBD_01261 0.0 1.1.1.320 Q Polyketide synthase of type I
HIMKHNBD_01262 0.0 1.1.1.320 Q Polyketide synthase of type I
HIMKHNBD_01263 0.0 pksJ Q Polyketide synthase of type I
HIMKHNBD_01264 0.0 pksJ Q Polyketide synthase of type I
HIMKHNBD_01265 1.1e-127 IQ reductase
HIMKHNBD_01266 3.8e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HIMKHNBD_01269 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HIMKHNBD_01270 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
HIMKHNBD_01271 1.1e-161 K LysR substrate binding domain
HIMKHNBD_01272 5.5e-50 S GlpM protein
HIMKHNBD_01273 1.3e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HIMKHNBD_01274 1.8e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HIMKHNBD_01275 6.1e-171 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HIMKHNBD_01276 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIMKHNBD_01277 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIMKHNBD_01278 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIMKHNBD_01279 2.4e-25 yqzJ
HIMKHNBD_01280 1.7e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIMKHNBD_01281 1.8e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HIMKHNBD_01282 4.8e-282 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HIMKHNBD_01283 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HIMKHNBD_01285 3.1e-95 yqjB S protein conserved in bacteria
HIMKHNBD_01286 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
HIMKHNBD_01287 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HIMKHNBD_01288 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
HIMKHNBD_01289 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
HIMKHNBD_01290 1e-75 yqiW S Belongs to the UPF0403 family
HIMKHNBD_01291 1.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HIMKHNBD_01292 4.6e-201 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIMKHNBD_01293 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HIMKHNBD_01294 9.5e-162 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HIMKHNBD_01295 1.3e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HIMKHNBD_01296 1.6e-205 buk 2.7.2.7 C Belongs to the acetokinase family
HIMKHNBD_01297 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HIMKHNBD_01298 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HIMKHNBD_01299 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HIMKHNBD_01300 1.8e-22 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HIMKHNBD_01301 9e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HIMKHNBD_01302 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HIMKHNBD_01303 7.2e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HIMKHNBD_01304 1.7e-202 mmgC I acyl-CoA dehydrogenase
HIMKHNBD_01305 2.2e-154 hbdA 1.1.1.157 I Dehydrogenase
HIMKHNBD_01306 5.7e-158 mmgA 2.3.1.9 I Belongs to the thiolase family
HIMKHNBD_01307 1.4e-39 mmgA 2.3.1.9 I Belongs to the thiolase family
HIMKHNBD_01308 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIMKHNBD_01309 5.7e-92 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HIMKHNBD_01310 1.2e-16
HIMKHNBD_01311 1.5e-101 ytaF P Probably functions as a manganese efflux pump
HIMKHNBD_01312 5.8e-112 K Protein of unknown function (DUF1232)
HIMKHNBD_01314 2.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HIMKHNBD_01318 2.1e-191 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIMKHNBD_01319 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HIMKHNBD_01320 8e-188 rseP 3.4.21.116 M Stage IV sporulation protein B
HIMKHNBD_01321 1.1e-44 rseP 3.4.21.116 M Stage IV sporulation protein B
HIMKHNBD_01322 7.9e-305 recN L May be involved in recombinational repair of damaged DNA
HIMKHNBD_01323 3.9e-78 argR K Regulates arginine biosynthesis genes
HIMKHNBD_01324 3.6e-134 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HIMKHNBD_01325 5e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HIMKHNBD_01326 2.5e-09
HIMKHNBD_01327 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HIMKHNBD_01329 2.3e-136 E GDSL-like Lipase/Acylhydrolase family
HIMKHNBD_01330 1.6e-149 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIMKHNBD_01331 2.8e-148 K Transcriptional regulator
HIMKHNBD_01332 5.2e-125 azlC E AzlC protein
HIMKHNBD_01333 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
HIMKHNBD_01334 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIMKHNBD_01335 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HIMKHNBD_01336 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HIMKHNBD_01337 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HIMKHNBD_01338 4e-228 acuC BQ histone deacetylase
HIMKHNBD_01339 3.7e-120 motS N Flagellar motor protein
HIMKHNBD_01340 6.6e-145 motA N flagellar motor
HIMKHNBD_01341 6.4e-182 ccpA K catabolite control protein A
HIMKHNBD_01342 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HIMKHNBD_01343 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
HIMKHNBD_01346 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HIMKHNBD_01347 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HIMKHNBD_01348 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HIMKHNBD_01349 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIMKHNBD_01350 3.7e-148 ytpQ S Belongs to the UPF0354 family
HIMKHNBD_01351 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HIMKHNBD_01352 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HIMKHNBD_01353 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HIMKHNBD_01354 1.7e-51 ytzB S small secreted protein
HIMKHNBD_01355 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HIMKHNBD_01356 2.1e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HIMKHNBD_01357 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIMKHNBD_01358 3.5e-45 ytzH S YtzH-like protein
HIMKHNBD_01359 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
HIMKHNBD_01360 2.9e-176 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HIMKHNBD_01361 1.2e-166 ytlQ
HIMKHNBD_01362 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HIMKHNBD_01363 3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HIMKHNBD_01364 4.7e-268 pepV 3.5.1.18 E Dipeptidase
HIMKHNBD_01365 1.3e-227 pbuO S permease
HIMKHNBD_01366 1.3e-215 ythQ U Bacterial ABC transporter protein EcsB
HIMKHNBD_01367 1.7e-128 ythP V ABC transporter
HIMKHNBD_01368 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HIMKHNBD_01369 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HIMKHNBD_01370 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMKHNBD_01371 2.2e-235 ytfP S HI0933-like protein
HIMKHNBD_01372 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HIMKHNBD_01373 9e-26 yteV S Sporulation protein Cse60
HIMKHNBD_01374 4.8e-185 msmR K Transcriptional regulator
HIMKHNBD_01375 4.9e-243 msmE G Bacterial extracellular solute-binding protein
HIMKHNBD_01376 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
HIMKHNBD_01377 1.8e-142 amyC P ABC transporter (permease)
HIMKHNBD_01378 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HIMKHNBD_01379 5.6e-83 M Acetyltransferase (GNAT) domain
HIMKHNBD_01380 2.5e-28 ytwF P Sulfurtransferase
HIMKHNBD_01381 3.9e-12 ytwF P Sulfurtransferase
HIMKHNBD_01382 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIMKHNBD_01383 1.2e-52 ytvB S Protein of unknown function (DUF4257)
HIMKHNBD_01384 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HIMKHNBD_01385 1.8e-207 yttB EGP Major facilitator Superfamily
HIMKHNBD_01386 1.4e-122 ywaF S Integral membrane protein
HIMKHNBD_01387 0.0 bceB V ABC transporter (permease)
HIMKHNBD_01388 1.4e-133 bceA V ABC transporter, ATP-binding protein
HIMKHNBD_01389 1.5e-178 T PhoQ Sensor
HIMKHNBD_01390 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMKHNBD_01391 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HIMKHNBD_01392 2.2e-125 ytrE V ABC transporter, ATP-binding protein
HIMKHNBD_01393 2.2e-150
HIMKHNBD_01394 2.7e-172 P ABC-2 family transporter protein
HIMKHNBD_01395 1.3e-163 S ABC-2 family transporter protein
HIMKHNBD_01396 4.2e-161 ytrB P abc transporter atp-binding protein
HIMKHNBD_01397 3.9e-66 ytrA K GntR family transcriptional regulator
HIMKHNBD_01399 7.4e-40 ytzC S Protein of unknown function (DUF2524)
HIMKHNBD_01400 6.8e-193 K helix_turn_helix, Arsenical Resistance Operon Repressor
HIMKHNBD_01401 2.2e-280 norB EGP COG0477 Permeases of the major facilitator superfamily
HIMKHNBD_01402 1.1e-189 yhcC S Fe-S oxidoreductase
HIMKHNBD_01403 2.8e-105 ytqB J Putative rRNA methylase
HIMKHNBD_01405 1.5e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
HIMKHNBD_01406 7.1e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HIMKHNBD_01407 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
HIMKHNBD_01408 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HIMKHNBD_01409 1.1e-259 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HIMKHNBD_01410 1.7e-229 asnB 6.3.5.4 E Asparagine synthase
HIMKHNBD_01411 4e-116 asnB 6.3.5.4 E Asparagine synthase
HIMKHNBD_01412 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIMKHNBD_01413 7.7e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HIMKHNBD_01414 1.6e-38 ytmB S Protein of unknown function (DUF2584)
HIMKHNBD_01415 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HIMKHNBD_01416 2.6e-183 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HIMKHNBD_01417 3.2e-144 ytlC P ABC transporter
HIMKHNBD_01418 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HIMKHNBD_01419 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HIMKHNBD_01420 5e-61 ytkC S Bacteriophage holin family
HIMKHNBD_01421 7.8e-76 dps P Belongs to the Dps family
HIMKHNBD_01423 7.4e-74 ytkA S YtkA-like
HIMKHNBD_01424 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIMKHNBD_01425 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HIMKHNBD_01426 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HIMKHNBD_01427 7.9e-41 rpmE2 J Ribosomal protein L31
HIMKHNBD_01428 3.2e-64 cydA 1.10.3.14 C oxidase, subunit
HIMKHNBD_01429 1.6e-166 cydA 1.10.3.14 C oxidase, subunit
HIMKHNBD_01430 1.5e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HIMKHNBD_01431 2e-23 S Domain of Unknown Function (DUF1540)
HIMKHNBD_01432 7.8e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HIMKHNBD_01433 4.1e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HIMKHNBD_01434 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HIMKHNBD_01435 7.9e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HIMKHNBD_01436 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HIMKHNBD_01437 9e-181 menF 5.4.4.2 HQ Isochorismate synthase
HIMKHNBD_01438 2.3e-24 menF 5.4.4.2 HQ Isochorismate synthase
HIMKHNBD_01439 1e-122 dksA T COG1734 DnaK suppressor protein
HIMKHNBD_01440 2.6e-77 tspO T membrane
HIMKHNBD_01449 7.8e-08
HIMKHNBD_01450 1.3e-09
HIMKHNBD_01457 1.6e-08
HIMKHNBD_01462 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HIMKHNBD_01463 2.1e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HIMKHNBD_01464 4.3e-183 pksD Q Acyl transferase domain
HIMKHNBD_01465 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HIMKHNBD_01466 5.5e-34 acpK IQ Phosphopantetheine attachment site
HIMKHNBD_01467 2.4e-242 pksG 2.3.3.10 I synthase
HIMKHNBD_01468 3.5e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
HIMKHNBD_01469 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HIMKHNBD_01470 0.0 rhiB IQ polyketide synthase
HIMKHNBD_01471 1.3e-193 rhiB IQ polyketide synthase
HIMKHNBD_01472 0.0 Q Polyketide synthase of type I
HIMKHNBD_01473 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HIMKHNBD_01474 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
HIMKHNBD_01475 6.8e-165 dhbF IQ polyketide synthase
HIMKHNBD_01476 0.0 dhbF IQ polyketide synthase
HIMKHNBD_01477 0.0 pks13 HQ Beta-ketoacyl synthase
HIMKHNBD_01478 0.0 pks13 HQ Beta-ketoacyl synthase
HIMKHNBD_01479 1.7e-229 cypA C Cytochrome P450
HIMKHNBD_01480 2e-55 nucB M Deoxyribonuclease NucA/NucB
HIMKHNBD_01481 3.6e-118 yoaK S Membrane
HIMKHNBD_01482 4.1e-62 ymzB
HIMKHNBD_01483 5.7e-255 aprX O Belongs to the peptidase S8 family
HIMKHNBD_01484 3e-125 ymaC S Replication protein
HIMKHNBD_01485 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
HIMKHNBD_01486 2.6e-53 ebrB P Small Multidrug Resistance protein
HIMKHNBD_01487 2.6e-47 ebrA P Small Multidrug Resistance protein
HIMKHNBD_01489 9.2e-47 ymaF S YmaF family
HIMKHNBD_01490 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIMKHNBD_01491 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HIMKHNBD_01492 3e-41
HIMKHNBD_01493 5.8e-18 ymzA
HIMKHNBD_01494 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HIMKHNBD_01495 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIMKHNBD_01496 1.4e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIMKHNBD_01497 2.2e-108 ymaB S MutT family
HIMKHNBD_01498 4.7e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMKHNBD_01499 1.3e-176 spoVK O stage V sporulation protein K
HIMKHNBD_01500 1.1e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIMKHNBD_01501 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HIMKHNBD_01502 4.3e-68 glnR K transcriptional
HIMKHNBD_01503 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
HIMKHNBD_01504 1.1e-208 mrjp G Major royal jelly protein
HIMKHNBD_01505 4.2e-248 xynT G MFS/sugar transport protein
HIMKHNBD_01506 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HIMKHNBD_01507 7.3e-206 xylR GK ROK family
HIMKHNBD_01508 1.2e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HIMKHNBD_01510 8.7e-284 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
HIMKHNBD_01511 4.3e-278 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HIMKHNBD_01512 1.3e-193 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HIMKHNBD_01516 4.1e-184 adhP 1.1.1.1 C alcohol dehydrogenase
HIMKHNBD_01517 4.8e-144 M cell wall anchor domain
HIMKHNBD_01518 4.6e-80 srtA 3.4.22.70 M Sortase family
HIMKHNBD_01519 2.8e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HIMKHNBD_01520 2.6e-118 citT T response regulator
HIMKHNBD_01521 4.6e-177 yflP S Tripartite tricarboxylate transporter family receptor
HIMKHNBD_01522 2.3e-224 citM C Citrate transporter
HIMKHNBD_01523 2.1e-148 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HIMKHNBD_01524 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HIMKHNBD_01525 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HIMKHNBD_01526 1.3e-122 yflK S protein conserved in bacteria
HIMKHNBD_01527 1.5e-14 yflJ S Protein of unknown function (DUF2639)
HIMKHNBD_01528 7e-19 yflI
HIMKHNBD_01529 7.6e-42 yflH S Protein of unknown function (DUF3243)
HIMKHNBD_01530 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
HIMKHNBD_01531 3.3e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HIMKHNBD_01532 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
HIMKHNBD_01533 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HIMKHNBD_01534 2.3e-63 yhdN S Domain of unknown function (DUF1992)
HIMKHNBD_01535 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
HIMKHNBD_01536 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
HIMKHNBD_01537 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
HIMKHNBD_01538 2.8e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMKHNBD_01539 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HIMKHNBD_01540 6.6e-87 treR K transcriptional
HIMKHNBD_01541 1.2e-123 yfkO C nitroreductase
HIMKHNBD_01542 1e-123 yibF S YibE/F-like protein
HIMKHNBD_01543 5.5e-198 yibE S YibE/F-like protein
HIMKHNBD_01544 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HIMKHNBD_01545 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HIMKHNBD_01546 9.8e-186 K helix_turn _helix lactose operon repressor
HIMKHNBD_01547 1.2e-163 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HIMKHNBD_01548 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HIMKHNBD_01549 8.1e-192 ydiM EGP Major facilitator Superfamily
HIMKHNBD_01550 2.7e-29 yfkK S Belongs to the UPF0435 family
HIMKHNBD_01551 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIMKHNBD_01552 1.7e-51 yfkI S gas vesicle protein
HIMKHNBD_01553 7.6e-144 yihY S Belongs to the UPF0761 family
HIMKHNBD_01554 2.5e-07
HIMKHNBD_01555 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HIMKHNBD_01556 2.2e-185 cax P COG0387 Ca2 H antiporter
HIMKHNBD_01557 1.6e-143 yfkD S YfkD-like protein
HIMKHNBD_01558 1e-145 yfkC M Mechanosensitive ion channel
HIMKHNBD_01559 3.3e-219 yfkA S YfkB-like domain
HIMKHNBD_01560 4.9e-27 yfjT
HIMKHNBD_01561 9e-155 pdaA G deacetylase
HIMKHNBD_01562 4e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HIMKHNBD_01563 1.1e-30
HIMKHNBD_01564 8.5e-184 corA P Mediates influx of magnesium ions
HIMKHNBD_01565 3.7e-162 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HIMKHNBD_01566 1.5e-261 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIMKHNBD_01567 8.7e-44 S YfzA-like protein
HIMKHNBD_01568 3.5e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIMKHNBD_01569 3.7e-87 yfjM S Psort location Cytoplasmic, score
HIMKHNBD_01570 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HIMKHNBD_01571 8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HIMKHNBD_01572 3.2e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIMKHNBD_01573 4.7e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HIMKHNBD_01574 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HIMKHNBD_01575 4.2e-15 sspH S Belongs to the SspH family
HIMKHNBD_01576 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HIMKHNBD_01577 8.8e-17 glvR F Helix-turn-helix domain, rpiR family
HIMKHNBD_01578 8.7e-90 glvR F Helix-turn-helix domain, rpiR family
HIMKHNBD_01579 9.2e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMKHNBD_01580 4.5e-308 yfiB3 V ABC transporter
HIMKHNBD_01581 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HIMKHNBD_01582 9.2e-63 mhqP S DoxX
HIMKHNBD_01583 1.7e-159 yfiE 1.13.11.2 S glyoxalase
HIMKHNBD_01584 3.9e-165 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HIMKHNBD_01585 6.6e-96 padR K transcriptional
HIMKHNBD_01586 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
HIMKHNBD_01587 7.2e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HIMKHNBD_01588 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
HIMKHNBD_01589 4.5e-45 yrdF K ribonuclease inhibitor
HIMKHNBD_01590 6.5e-96 yfiT S Belongs to the metal hydrolase YfiT family
HIMKHNBD_01591 1.1e-289 yfiU EGP Major facilitator Superfamily
HIMKHNBD_01592 8.1e-82 yfiV K transcriptional
HIMKHNBD_01593 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIMKHNBD_01594 7.2e-161 yfhB 5.3.3.17 S PhzF family
HIMKHNBD_01595 3.3e-106 yfhC C nitroreductase
HIMKHNBD_01596 2.1e-25 yfhD S YfhD-like protein
HIMKHNBD_01598 3.4e-166 yfhF S nucleoside-diphosphate sugar epimerase
HIMKHNBD_01599 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
HIMKHNBD_01600 2.5e-52 yfhH S Protein of unknown function (DUF1811)
HIMKHNBD_01601 1.1e-204 yfhI EGP Major facilitator Superfamily
HIMKHNBD_01603 2e-166 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HIMKHNBD_01604 2.2e-44 yfhJ S WVELL protein
HIMKHNBD_01605 1.7e-93 batE T Bacterial SH3 domain homologues
HIMKHNBD_01606 6.3e-33 yfhL S SdpI/YhfL protein family
HIMKHNBD_01607 2e-168 yfhM S Alpha/beta hydrolase family
HIMKHNBD_01608 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMKHNBD_01609 0.0 yfhO S Bacterial membrane protein YfhO
HIMKHNBD_01610 1e-184 yfhP S membrane-bound metal-dependent
HIMKHNBD_01611 1.4e-206 mutY L A G-specific
HIMKHNBD_01612 3.1e-36 yfhS
HIMKHNBD_01613 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMKHNBD_01615 1.5e-37 ygaB S YgaB-like protein
HIMKHNBD_01616 2.2e-104 ygaC J Belongs to the UPF0374 family
HIMKHNBD_01617 9.1e-301 ygaD V ABC transporter
HIMKHNBD_01618 2.7e-178 ygaE S Membrane
HIMKHNBD_01619 1.8e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HIMKHNBD_01620 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
HIMKHNBD_01621 1.8e-80 perR P Belongs to the Fur family
HIMKHNBD_01622 3.3e-56 ygzB S UPF0295 protein
HIMKHNBD_01623 1.4e-161 ygxA S Nucleotidyltransferase-like
HIMKHNBD_01624 4.4e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HIMKHNBD_01625 1.9e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HIMKHNBD_01626 9.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HIMKHNBD_01627 8.3e-110 ywqC M biosynthesis protein
HIMKHNBD_01628 1.3e-14
HIMKHNBD_01629 1.6e-307 ywqB S SWIM zinc finger
HIMKHNBD_01630 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HIMKHNBD_01631 1.7e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HIMKHNBD_01632 7.5e-138 glcR K DeoR C terminal sensor domain
HIMKHNBD_01633 3.7e-57 ssbB L Single-stranded DNA-binding protein
HIMKHNBD_01634 4e-62 ywpG
HIMKHNBD_01635 2.5e-68 ywpF S YwpF-like protein
HIMKHNBD_01636 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HIMKHNBD_01637 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HIMKHNBD_01638 2.1e-89 S aspartate phosphatase
HIMKHNBD_01639 1.7e-93 S aspartate phosphatase
HIMKHNBD_01640 2.4e-142 flhP N flagellar basal body
HIMKHNBD_01641 5.5e-128 flhO N flagellar basal body
HIMKHNBD_01642 2.7e-180 mbl D Rod shape-determining protein
HIMKHNBD_01643 1.8e-44 spoIIID K Stage III sporulation protein D
HIMKHNBD_01644 4.2e-71 ywoH K transcriptional
HIMKHNBD_01645 5e-100 ywoG EGP Major facilitator Superfamily
HIMKHNBD_01646 9.4e-101 ywoG EGP Major facilitator Superfamily
HIMKHNBD_01647 1.2e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HIMKHNBD_01648 1.8e-188 ywoD EGP Major facilitator superfamily
HIMKHNBD_01649 4.8e-102 phzA Q Isochorismatase family
HIMKHNBD_01650 2.5e-228 amt P Ammonium transporter
HIMKHNBD_01651 2e-58 nrgB K Belongs to the P(II) protein family
HIMKHNBD_01652 3.9e-207 ftsW D Belongs to the SEDS family
HIMKHNBD_01653 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HIMKHNBD_01654 5.6e-71 ywnJ S VanZ like family
HIMKHNBD_01655 3.8e-121 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HIMKHNBD_01656 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HIMKHNBD_01657 1.2e-10 ywnC S Family of unknown function (DUF5362)
HIMKHNBD_01658 1.2e-68 ywnF S Family of unknown function (DUF5392)
HIMKHNBD_01659 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIMKHNBD_01660 1.2e-51 ywnC S Family of unknown function (DUF5362)
HIMKHNBD_01661 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HIMKHNBD_01662 6.1e-67 ywnA K Transcriptional regulator
HIMKHNBD_01663 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HIMKHNBD_01664 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HIMKHNBD_01665 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HIMKHNBD_01666 1.4e-10 csbD K CsbD-like
HIMKHNBD_01667 2.3e-81 ywmF S Peptidase M50
HIMKHNBD_01668 2.8e-93 S response regulator aspartate phosphatase
HIMKHNBD_01669 2.6e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HIMKHNBD_01670 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HIMKHNBD_01672 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HIMKHNBD_01673 1.5e-113 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HIMKHNBD_01674 1.2e-178 spoIID D Stage II sporulation protein D
HIMKHNBD_01675 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIMKHNBD_01676 1.1e-133 ywmB S TATA-box binding
HIMKHNBD_01677 4.8e-32 ywzB S membrane
HIMKHNBD_01678 7.3e-88 ywmA
HIMKHNBD_01679 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HIMKHNBD_01680 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIMKHNBD_01681 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIMKHNBD_01682 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIMKHNBD_01683 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIMKHNBD_01684 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIMKHNBD_01685 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIMKHNBD_01686 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
HIMKHNBD_01687 6.2e-40 atpI S ATP synthase
HIMKHNBD_01688 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIMKHNBD_01689 5.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HIMKHNBD_01690 1.7e-96 ywlG S Belongs to the UPF0340 family
HIMKHNBD_01691 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HIMKHNBD_01692 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIMKHNBD_01693 1.3e-83 mntP P Probably functions as a manganese efflux pump
HIMKHNBD_01694 1.5e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HIMKHNBD_01695 3.9e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HIMKHNBD_01696 8.9e-119 spoIIR S stage II sporulation protein R
HIMKHNBD_01697 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
HIMKHNBD_01699 4.8e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIMKHNBD_01700 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIMKHNBD_01701 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMKHNBD_01702 2.2e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HIMKHNBD_01703 6.8e-157 ywkB S Membrane transport protein
HIMKHNBD_01704 0.0 sfcA 1.1.1.38 C malic enzyme
HIMKHNBD_01705 1.7e-102 tdk 2.7.1.21 F thymidine kinase
HIMKHNBD_01706 1.1e-32 rpmE J Binds the 23S rRNA
HIMKHNBD_01707 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HIMKHNBD_01708 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HIMKHNBD_01709 2.1e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIMKHNBD_01710 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HIMKHNBD_01711 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HIMKHNBD_01712 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
HIMKHNBD_01713 2.4e-92 ywjG S Domain of unknown function (DUF2529)
HIMKHNBD_01714 4.2e-183 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIMKHNBD_01715 1.1e-110 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIMKHNBD_01716 1.6e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HIMKHNBD_01717 0.0 fadF C COG0247 Fe-S oxidoreductase
HIMKHNBD_01718 2.3e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HIMKHNBD_01719 9.8e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HIMKHNBD_01720 4.2e-43 ywjC
HIMKHNBD_01721 0.0 ywjA V ABC transporter
HIMKHNBD_01722 1.6e-296 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIMKHNBD_01723 3.4e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIMKHNBD_01724 2.1e-120 narI 1.7.5.1 C nitrate reductase, gamma
HIMKHNBD_01725 7.9e-89 narJ 1.7.5.1 C nitrate reductase
HIMKHNBD_01726 6.3e-295 narH 1.7.5.1 C Nitrate reductase, beta
HIMKHNBD_01727 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIMKHNBD_01728 1.3e-84 arfM T cyclic nucleotide binding
HIMKHNBD_01729 2.8e-139 ywiC S YwiC-like protein
HIMKHNBD_01730 5e-128 fnr K helix_turn_helix, cAMP Regulatory protein
HIMKHNBD_01731 5.4e-212 narK P COG2223 Nitrate nitrite transporter
HIMKHNBD_01732 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HIMKHNBD_01733 2.9e-43 ywiB S protein conserved in bacteria
HIMKHNBD_01734 1.1e-174 S Psort location CytoplasmicMembrane, score
HIMKHNBD_01735 8.3e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIMKHNBD_01736 3.8e-54 swrA S Swarming motility protein
HIMKHNBD_01737 1.1e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HIMKHNBD_01738 8.6e-225 ywoF P Right handed beta helix region
HIMKHNBD_01739 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HIMKHNBD_01740 2.3e-122 ftsE D cell division ATP-binding protein FtsE
HIMKHNBD_01741 8.1e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
HIMKHNBD_01742 1.5e-147 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HIMKHNBD_01743 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIMKHNBD_01744 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIMKHNBD_01745 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIMKHNBD_01746 6.8e-68
HIMKHNBD_01747 5.9e-10 fliT S bacterial-type flagellum organization
HIMKHNBD_01748 3e-66 fliS N flagellar protein FliS
HIMKHNBD_01749 1.3e-178 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HIMKHNBD_01750 2.1e-45 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HIMKHNBD_01751 9.4e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HIMKHNBD_01752 2.6e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HIMKHNBD_01753 7.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HIMKHNBD_01754 1.4e-80 yviE
HIMKHNBD_01755 2.3e-162 flgL N Belongs to the bacterial flagellin family
HIMKHNBD_01756 1.4e-273 flgK N flagellar hook-associated protein
HIMKHNBD_01757 8.9e-81 flgN NOU FlgN protein
HIMKHNBD_01758 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
HIMKHNBD_01759 4.1e-74 yvyF S flagellar protein
HIMKHNBD_01760 6.5e-76 comFC S Phosphoribosyl transferase domain
HIMKHNBD_01761 1.7e-42 comFB S Late competence development protein ComFB
HIMKHNBD_01762 3.2e-256 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HIMKHNBD_01763 4.2e-158 degV S protein conserved in bacteria
HIMKHNBD_01764 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMKHNBD_01765 3.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HIMKHNBD_01766 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HIMKHNBD_01767 1e-165 yvhJ K Transcriptional regulator
HIMKHNBD_01768 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HIMKHNBD_01769 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HIMKHNBD_01770 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
HIMKHNBD_01771 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
HIMKHNBD_01772 4.6e-21 tuaE M Teichuronic acid biosynthesis protein
HIMKHNBD_01773 9.5e-223 tuaE M Teichuronic acid biosynthesis protein
HIMKHNBD_01774 1.2e-247 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HIMKHNBD_01775 8.9e-223 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HIMKHNBD_01776 6.1e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMKHNBD_01777 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HIMKHNBD_01778 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMKHNBD_01779 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HIMKHNBD_01780 2.3e-48
HIMKHNBD_01781 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HIMKHNBD_01782 2e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIMKHNBD_01783 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HIMKHNBD_01784 5.4e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HIMKHNBD_01785 1.7e-151 tagG GM Transport permease protein
HIMKHNBD_01786 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HIMKHNBD_01787 2.1e-280 M Glycosyltransferase like family 2
HIMKHNBD_01788 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HIMKHNBD_01789 3.8e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HIMKHNBD_01790 1.6e-216 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HIMKHNBD_01791 2e-238 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIMKHNBD_01792 7.7e-185 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HIMKHNBD_01793 5.7e-264 gerBA EG Spore germination protein
HIMKHNBD_01794 5.4e-198 gerBB E Spore germination protein
HIMKHNBD_01795 8.2e-210 gerAC S Spore germination protein
HIMKHNBD_01796 4.4e-266 GT2,GT4 J Glycosyl transferase family 2
HIMKHNBD_01797 5e-235 ywtG EGP Major facilitator Superfamily
HIMKHNBD_01798 7.2e-178 ywtF K Transcriptional regulator
HIMKHNBD_01799 4.7e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HIMKHNBD_01800 1.6e-18 yttA 2.7.13.3 S Pfam Transposase IS66
HIMKHNBD_01801 7.3e-236 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HIMKHNBD_01802 1.3e-20 ywtC
HIMKHNBD_01803 2.8e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HIMKHNBD_01804 2.3e-70 pgsC S biosynthesis protein
HIMKHNBD_01805 8.8e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HIMKHNBD_01806 2.8e-186 gerKA EG Spore germination protein
HIMKHNBD_01807 8.2e-191 gerKB E Spore germination protein
HIMKHNBD_01808 4.6e-178 gerKC S Spore germination B3/ GerAC like, C-terminal
HIMKHNBD_01809 1.5e-178 rbsR K transcriptional
HIMKHNBD_01810 1.2e-155 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIMKHNBD_01811 3.4e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HIMKHNBD_01812 3.9e-257 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HIMKHNBD_01813 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
HIMKHNBD_01814 3.7e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HIMKHNBD_01815 1.5e-89 batE T Sh3 type 3 domain protein
HIMKHNBD_01816 5.3e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
HIMKHNBD_01817 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HIMKHNBD_01818 6.8e-309 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HIMKHNBD_01819 2.6e-166 alsR K LysR substrate binding domain
HIMKHNBD_01821 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HIMKHNBD_01822 6.3e-125 ywrJ
HIMKHNBD_01823 2.8e-128 cotB
HIMKHNBD_01824 5.5e-211 cotH M Spore Coat
HIMKHNBD_01825 7.5e-10
HIMKHNBD_01826 4.2e-228 yukF QT Transcriptional regulator
HIMKHNBD_01827 3.9e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HIMKHNBD_01828 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HIMKHNBD_01829 1.1e-33 mbtH S MbtH-like protein
HIMKHNBD_01830 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_01831 5.2e-170 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HIMKHNBD_01832 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HIMKHNBD_01833 8.6e-218 entC 5.4.4.2 HQ Isochorismate synthase
HIMKHNBD_01834 1.5e-130 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMKHNBD_01835 1.2e-163 besA S Putative esterase
HIMKHNBD_01836 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
HIMKHNBD_01837 1.9e-101 bioY S Biotin biosynthesis protein
HIMKHNBD_01838 2.6e-207 yuiF S antiporter
HIMKHNBD_01839 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HIMKHNBD_01840 1.6e-77 yuiD S protein conserved in bacteria
HIMKHNBD_01841 2.7e-117 yuiC S protein conserved in bacteria
HIMKHNBD_01842 9.9e-28 yuiB S Putative membrane protein
HIMKHNBD_01843 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
HIMKHNBD_01844 7.5e-64 yumC 1.18.1.2, 1.19.1.1 C reductase
HIMKHNBD_01845 1.6e-64 yumC 1.18.1.2, 1.19.1.1 C reductase
HIMKHNBD_01847 1.1e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIMKHNBD_01848 4.8e-29
HIMKHNBD_01849 2.6e-70 CP Membrane
HIMKHNBD_01850 1.5e-121 V ABC transporter
HIMKHNBD_01852 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
HIMKHNBD_01854 2.3e-26 K helix_turn_helix, mercury resistance
HIMKHNBD_01855 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMKHNBD_01856 1.1e-62 erpA S Belongs to the HesB IscA family
HIMKHNBD_01857 1.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HIMKHNBD_01858 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIMKHNBD_01859 9.2e-39 yuzB S Belongs to the UPF0349 family
HIMKHNBD_01860 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
HIMKHNBD_01861 1.1e-53 yuzD S protein conserved in bacteria
HIMKHNBD_01862 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HIMKHNBD_01863 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HIMKHNBD_01864 9.8e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIMKHNBD_01865 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HIMKHNBD_01866 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
HIMKHNBD_01867 3e-195 yutH S Spore coat protein
HIMKHNBD_01868 3.3e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HIMKHNBD_01869 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HIMKHNBD_01870 6.8e-72 yutE S Protein of unknown function DUF86
HIMKHNBD_01871 1.7e-47 yutD S protein conserved in bacteria
HIMKHNBD_01872 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HIMKHNBD_01873 6.6e-192 lytH M Peptidase, M23
HIMKHNBD_01874 3.3e-130 yunB S Sporulation protein YunB (Spo_YunB)
HIMKHNBD_01875 1.9e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HIMKHNBD_01876 5.1e-145 yunE S membrane transporter protein
HIMKHNBD_01877 3.1e-169 yunF S Protein of unknown function DUF72
HIMKHNBD_01878 2.4e-59 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
HIMKHNBD_01879 1e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HIMKHNBD_01880 4.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
HIMKHNBD_01881 7e-21 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HIMKHNBD_01882 1.5e-21
HIMKHNBD_01884 4.1e-212 blt EGP Major facilitator Superfamily
HIMKHNBD_01885 3.7e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HIMKHNBD_01886 6.8e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HIMKHNBD_01887 2.8e-165 bsn L Ribonuclease
HIMKHNBD_01888 1e-204 msmX P Belongs to the ABC transporter superfamily
HIMKHNBD_01889 3.6e-134 yurK K UTRA
HIMKHNBD_01890 1.5e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HIMKHNBD_01891 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
HIMKHNBD_01892 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
HIMKHNBD_01893 1.5e-244 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HIMKHNBD_01894 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HIMKHNBD_01895 1.9e-164 K helix_turn_helix, mercury resistance
HIMKHNBD_01897 7.7e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HIMKHNBD_01898 6.8e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HIMKHNBD_01899 7.5e-129 Q ubiE/COQ5 methyltransferase family
HIMKHNBD_01900 2.9e-63 yncE S Protein of unknown function (DUF2691)
HIMKHNBD_01901 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HIMKHNBD_01902 8.7e-270 sufB O FeS cluster assembly
HIMKHNBD_01903 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HIMKHNBD_01904 1.4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HIMKHNBD_01905 1.2e-244 sufD O assembly protein SufD
HIMKHNBD_01906 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HIMKHNBD_01907 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HIMKHNBD_01908 3e-145 metQ P Belongs to the NlpA lipoprotein family
HIMKHNBD_01909 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HIMKHNBD_01910 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIMKHNBD_01911 1.5e-56 yusD S SCP-2 sterol transfer family
HIMKHNBD_01912 1.6e-54 yusE CO Thioredoxin
HIMKHNBD_01913 4.9e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HIMKHNBD_01914 3.7e-40 yusG S Protein of unknown function (DUF2553)
HIMKHNBD_01915 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HIMKHNBD_01916 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HIMKHNBD_01917 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HIMKHNBD_01918 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HIMKHNBD_01919 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HIMKHNBD_01920 1.4e-164 fadM E Proline dehydrogenase
HIMKHNBD_01921 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_01922 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HIMKHNBD_01923 3.4e-140 srfAD Q thioesterase
HIMKHNBD_01924 3e-248 bamJ E Aminotransferase class I and II
HIMKHNBD_01925 2.3e-56 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HIMKHNBD_01926 6.5e-66 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HIMKHNBD_01927 2.7e-52 yczE S membrane
HIMKHNBD_01928 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HIMKHNBD_01929 6.3e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
HIMKHNBD_01930 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HIMKHNBD_01931 3.9e-159 bsdA K LysR substrate binding domain
HIMKHNBD_01932 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HIMKHNBD_01933 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HIMKHNBD_01934 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
HIMKHNBD_01935 1.3e-76 yclD
HIMKHNBD_01936 1.2e-269 dtpT E amino acid peptide transporter
HIMKHNBD_01937 1.6e-276 yclG M Pectate lyase superfamily protein
HIMKHNBD_01939 9.4e-270 gerKA EG Spore germination protein
HIMKHNBD_01940 5.2e-234 gerKC S spore germination
HIMKHNBD_01941 1.1e-195 gerKB F Spore germination protein
HIMKHNBD_01942 1.8e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMKHNBD_01943 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMKHNBD_01944 2.4e-84 yxeM M Belongs to the bacterial solute-binding protein 3 family
HIMKHNBD_01945 5.1e-38 yxeM M Belongs to the bacterial solute-binding protein 3 family
HIMKHNBD_01946 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
HIMKHNBD_01947 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HIMKHNBD_01948 6.4e-218 yxeP 3.5.1.47 E hydrolase activity
HIMKHNBD_01949 5.3e-248 yxeQ S MmgE/PrpD family
HIMKHNBD_01950 3.1e-119 yclH P ABC transporter
HIMKHNBD_01951 5.6e-83 yclI V ABC transporter (permease) YclI
HIMKHNBD_01952 1.2e-141 yclI V ABC transporter (permease) YclI
HIMKHNBD_01953 6.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMKHNBD_01954 6.4e-260 T PhoQ Sensor
HIMKHNBD_01955 9.5e-81 S aspartate phosphatase
HIMKHNBD_01957 1.6e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
HIMKHNBD_01958 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMKHNBD_01959 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMKHNBD_01960 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HIMKHNBD_01961 1e-173 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HIMKHNBD_01962 2.1e-247 ycnB EGP Major facilitator Superfamily
HIMKHNBD_01963 2.5e-150 ycnC K Transcriptional regulator
HIMKHNBD_01964 1.5e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
HIMKHNBD_01965 1e-44 ycnE S Monooxygenase
HIMKHNBD_01966 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HIMKHNBD_01967 6.7e-262 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIMKHNBD_01968 2.1e-217 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIMKHNBD_01969 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIMKHNBD_01970 6.1e-149 glcU U Glucose uptake
HIMKHNBD_01971 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMKHNBD_01972 2.3e-97 ycnI S protein conserved in bacteria
HIMKHNBD_01973 2.6e-297 ycnJ P protein, homolog of Cu resistance protein CopC
HIMKHNBD_01974 2.1e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HIMKHNBD_01975 5e-54
HIMKHNBD_01976 1.8e-230 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HIMKHNBD_01977 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HIMKHNBD_01978 1.1e-206 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HIMKHNBD_01979 6.6e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HIMKHNBD_01981 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HIMKHNBD_01982 3e-139 ycsF S Belongs to the UPF0271 (lamB) family
HIMKHNBD_01983 5.7e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HIMKHNBD_01984 2.2e-103 ycsI S Belongs to the D-glutamate cyclase family
HIMKHNBD_01985 2.1e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HIMKHNBD_01986 5.9e-106 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HIMKHNBD_01987 1e-69 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HIMKHNBD_01988 1.3e-129 kipR K Transcriptional regulator
HIMKHNBD_01989 2.7e-117 ycsK E anatomical structure formation involved in morphogenesis
HIMKHNBD_01991 5.1e-56 yczJ S biosynthesis
HIMKHNBD_01992 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HIMKHNBD_01993 3.7e-173 ydhF S Oxidoreductase
HIMKHNBD_01994 0.0 mtlR K transcriptional regulator, MtlR
HIMKHNBD_01995 1.6e-285 ydaB IQ acyl-CoA ligase
HIMKHNBD_01996 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMKHNBD_01997 1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HIMKHNBD_01998 3.2e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HIMKHNBD_01999 1.4e-77 ydaG 1.4.3.5 S general stress protein
HIMKHNBD_02000 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HIMKHNBD_02001 1.3e-47 ydzA EGP Major facilitator Superfamily
HIMKHNBD_02002 4.3e-74 lrpC K Transcriptional regulator
HIMKHNBD_02003 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIMKHNBD_02004 5.6e-200 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HIMKHNBD_02005 2.8e-146 ydaK T Diguanylate cyclase, GGDEF domain
HIMKHNBD_02006 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HIMKHNBD_02007 7.2e-231 ydaM M Glycosyl transferase family group 2
HIMKHNBD_02008 0.0 ydaN S Bacterial cellulose synthase subunit
HIMKHNBD_02009 0.0 ydaO E amino acid
HIMKHNBD_02010 1.1e-72 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HIMKHNBD_02011 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HIMKHNBD_02012 6.6e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HIMKHNBD_02013 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIMKHNBD_02014 7.9e-11 yhfH S YhfH-like protein
HIMKHNBD_02015 2.2e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HIMKHNBD_02016 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
HIMKHNBD_02017 7.9e-109 yhfK GM NmrA-like family
HIMKHNBD_02018 4.1e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HIMKHNBD_02019 2.2e-34 yhfM
HIMKHNBD_02020 1e-14 yhfM
HIMKHNBD_02021 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
HIMKHNBD_02022 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HIMKHNBD_02023 1.4e-148 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HIMKHNBD_02024 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HIMKHNBD_02025 4.3e-200 vraB 2.3.1.9 I Belongs to the thiolase family
HIMKHNBD_02026 8.9e-278 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HIMKHNBD_02027 3.5e-89 bioY S BioY family
HIMKHNBD_02028 3.1e-197 hemAT NT chemotaxis protein
HIMKHNBD_02029 3.5e-296 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HIMKHNBD_02030 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMKHNBD_02031 5.4e-31 yhzC S IDEAL
HIMKHNBD_02032 1.9e-109 comK K Competence transcription factor
HIMKHNBD_02033 1.2e-66 frataxin S Domain of unknown function (DU1801)
HIMKHNBD_02034 9.3e-62 frataxin S Domain of unknown function (DU1801)
HIMKHNBD_02035 8.7e-125 yrpD S Domain of unknown function, YrpD
HIMKHNBD_02036 1.6e-42 yhjA S Excalibur calcium-binding domain
HIMKHNBD_02037 3.3e-47 S Belongs to the UPF0145 family
HIMKHNBD_02038 2.1e-200 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMKHNBD_02039 2.5e-44 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMKHNBD_02040 3.1e-27 yhjC S Protein of unknown function (DUF3311)
HIMKHNBD_02041 1.4e-59 yhjD
HIMKHNBD_02042 2.6e-109 yhjE S SNARE associated Golgi protein
HIMKHNBD_02043 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HIMKHNBD_02045 9.2e-270 yhjG CH FAD binding domain
HIMKHNBD_02046 8.4e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
HIMKHNBD_02047 1.8e-188 abrB S membrane
HIMKHNBD_02048 3e-202 blt EGP Major facilitator Superfamily
HIMKHNBD_02049 1.9e-107 K QacR-like protein, C-terminal region
HIMKHNBD_02050 6.3e-93 yhjR S Rubrerythrin
HIMKHNBD_02051 2.8e-64 ydfS S Protein of unknown function (DUF421)
HIMKHNBD_02052 2.5e-10 ydfS S Protein of unknown function (DUF421)
HIMKHNBD_02053 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HIMKHNBD_02054 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HIMKHNBD_02055 1.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HIMKHNBD_02056 0.0 sbcC L COG0419 ATPase involved in DNA repair
HIMKHNBD_02057 1.3e-50 yisB V COG1403 Restriction endonuclease
HIMKHNBD_02058 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
HIMKHNBD_02059 1.1e-63 gerPE S Spore germination protein GerPE
HIMKHNBD_02060 3.1e-23 gerPD S Spore germination protein
HIMKHNBD_02061 1.4e-62 gerPC S Spore germination protein
HIMKHNBD_02062 1.8e-34 gerPB S cell differentiation
HIMKHNBD_02063 8.4e-34 gerPA S Spore germination protein
HIMKHNBD_02064 4.8e-07 yisI S Spo0E like sporulation regulatory protein
HIMKHNBD_02065 7.8e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HIMKHNBD_02066 3.2e-59 yisL S UPF0344 protein
HIMKHNBD_02067 3.4e-97 yisN S Protein of unknown function (DUF2777)
HIMKHNBD_02068 0.0 asnO 6.3.5.4 E Asparagine synthase
HIMKHNBD_02069 2.5e-130 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HIMKHNBD_02070 1.5e-245 yisQ V Mate efflux family protein
HIMKHNBD_02071 5e-159 yisR K Transcriptional regulator
HIMKHNBD_02072 7.1e-144 purR K helix_turn _helix lactose operon repressor
HIMKHNBD_02073 5.8e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HIMKHNBD_02074 4.4e-83 yisT S DinB family
HIMKHNBD_02075 1.6e-69 mcbG S Pentapeptide repeats (9 copies)
HIMKHNBD_02076 3.4e-79 yjcF S Acetyltransferase (GNAT) domain
HIMKHNBD_02077 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HIMKHNBD_02078 6.6e-55 yajQ S Belongs to the UPF0234 family
HIMKHNBD_02079 7.6e-160 cvfB S protein conserved in bacteria
HIMKHNBD_02080 1.1e-170 yufN S ABC transporter substrate-binding protein PnrA-like
HIMKHNBD_02081 6.5e-232 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HIMKHNBD_02083 3e-156 yitS S protein conserved in bacteria
HIMKHNBD_02084 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HIMKHNBD_02085 2.7e-79 ipi S Intracellular proteinase inhibitor
HIMKHNBD_02086 4.4e-26 S Protein of unknown function (DUF3813)
HIMKHNBD_02087 3.5e-07
HIMKHNBD_02088 9.5e-152 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HIMKHNBD_02089 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HIMKHNBD_02090 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HIMKHNBD_02091 1.7e-72 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HIMKHNBD_02092 2.5e-272 yitY C D-arabinono-1,4-lactone oxidase
HIMKHNBD_02093 1.2e-89 norB G Major Facilitator Superfamily
HIMKHNBD_02094 1.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HIMKHNBD_02095 3e-226 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HIMKHNBD_02096 1.1e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HIMKHNBD_02097 1.9e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HIMKHNBD_02098 1.3e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIMKHNBD_02099 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HIMKHNBD_02100 1.3e-174 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HIMKHNBD_02101 1.2e-27 yjzC S YjzC-like protein
HIMKHNBD_02102 3.3e-23 yjzD S Protein of unknown function (DUF2929)
HIMKHNBD_02103 8.4e-139 yjaU I carboxylic ester hydrolase activity
HIMKHNBD_02104 3.7e-102 yjaV
HIMKHNBD_02105 2.7e-165 med S Transcriptional activator protein med
HIMKHNBD_02106 1.1e-26 comZ S ComZ
HIMKHNBD_02107 1e-31 yjzB
HIMKHNBD_02108 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIMKHNBD_02109 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIMKHNBD_02110 5.6e-149 yjaZ O Zn-dependent protease
HIMKHNBD_02111 4.8e-182 appD P Belongs to the ABC transporter superfamily
HIMKHNBD_02112 1.1e-148 appF E Belongs to the ABC transporter superfamily
HIMKHNBD_02113 7.1e-61 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HIMKHNBD_02114 5.6e-62 ycbP S Protein of unknown function (DUF2512)
HIMKHNBD_02115 5.3e-77 sleB 3.5.1.28 M Cell wall
HIMKHNBD_02116 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HIMKHNBD_02117 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HIMKHNBD_02118 3.8e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HIMKHNBD_02119 1.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HIMKHNBD_02120 2.9e-101 ycbU E Selenocysteine lyase
HIMKHNBD_02121 4.8e-85 ycbU E Selenocysteine lyase
HIMKHNBD_02122 1e-241 lmrB EGP the major facilitator superfamily
HIMKHNBD_02123 1e-99 yxaF K Transcriptional regulator
HIMKHNBD_02124 8.1e-194 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HIMKHNBD_02125 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HIMKHNBD_02126 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
HIMKHNBD_02127 1.5e-169 yccK C Aldo keto reductase
HIMKHNBD_02128 1.5e-175 ycdA S Domain of unknown function (DUF5105)
HIMKHNBD_02129 6.1e-255 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HIMKHNBD_02130 1.5e-222 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HIMKHNBD_02131 5.8e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
HIMKHNBD_02132 1e-188 S response regulator aspartate phosphatase
HIMKHNBD_02133 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HIMKHNBD_02134 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HIMKHNBD_02135 2.3e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
HIMKHNBD_02136 5.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HIMKHNBD_02137 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HIMKHNBD_02138 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMKHNBD_02139 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HIMKHNBD_02140 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
HIMKHNBD_02141 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
HIMKHNBD_02142 9.7e-138 terC P Protein of unknown function (DUF475)
HIMKHNBD_02143 0.0 yceG S Putative component of 'biosynthetic module'
HIMKHNBD_02144 6.7e-193 yceH P Belongs to the TelA family
HIMKHNBD_02145 2e-214 naiP P Uncharacterised MFS-type transporter YbfB
HIMKHNBD_02146 3.9e-229 proV 3.6.3.32 E glycine betaine
HIMKHNBD_02147 1.6e-138 opuAB P glycine betaine
HIMKHNBD_02148 1.5e-163 opuAC E glycine betaine
HIMKHNBD_02149 2.8e-210 amhX S amidohydrolase
HIMKHNBD_02150 2.5e-227 ycgA S Membrane
HIMKHNBD_02151 3.3e-31 ycgB
HIMKHNBD_02152 4.2e-37 ycgB
HIMKHNBD_02153 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HIMKHNBD_02154 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIMKHNBD_02155 8.1e-261 mdr EGP Major facilitator Superfamily
HIMKHNBD_02156 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
HIMKHNBD_02157 3e-113 ycgF E Lysine exporter protein LysE YggA
HIMKHNBD_02158 7.6e-151 yqcI S YqcI/YcgG family
HIMKHNBD_02159 6.4e-246 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HIMKHNBD_02160 1.3e-113 ycgI S Domain of unknown function (DUF1989)
HIMKHNBD_02161 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HIMKHNBD_02163 3.6e-108 tmrB S AAA domain
HIMKHNBD_02164 3e-142 4.2.1.118 G Xylose isomerase-like TIM barrel
HIMKHNBD_02165 4.8e-222 G COG0477 Permeases of the major facilitator superfamily
HIMKHNBD_02166 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HIMKHNBD_02167 6.5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HIMKHNBD_02168 8.9e-147 ycgL S Predicted nucleotidyltransferase
HIMKHNBD_02169 8.7e-170 ycgM E Proline dehydrogenase
HIMKHNBD_02170 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HIMKHNBD_02171 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMKHNBD_02172 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HIMKHNBD_02173 4.9e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HIMKHNBD_02174 3.2e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HIMKHNBD_02175 3e-56 nirD 1.7.1.15 P Nitrite reductase
HIMKHNBD_02176 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HIMKHNBD_02177 5.1e-226 yciC S GTPases (G3E family)
HIMKHNBD_02178 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HIMKHNBD_02179 1.1e-72 yckC S membrane
HIMKHNBD_02180 1.3e-48 S Protein of unknown function (DUF2680)
HIMKHNBD_02181 9e-11 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIMKHNBD_02182 1.5e-65 nin S Competence protein J (ComJ)
HIMKHNBD_02183 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
HIMKHNBD_02184 1.9e-82 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HIMKHNBD_02185 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HIMKHNBD_02186 2.6e-61 hxlR K transcriptional
HIMKHNBD_02187 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_02188 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_02189 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_02190 7.2e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HIMKHNBD_02191 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HIMKHNBD_02192 8.8e-89 gltC K Transcriptional regulator
HIMKHNBD_02193 6.1e-48 gltC K Transcriptional regulator
HIMKHNBD_02194 1.8e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HIMKHNBD_02195 3.4e-121 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIMKHNBD_02196 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HIMKHNBD_02197 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMKHNBD_02198 2.4e-39 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HIMKHNBD_02199 6.4e-134 yoxB
HIMKHNBD_02200 4.8e-203 yoaB EGP Major facilitator Superfamily
HIMKHNBD_02201 1.7e-268 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
HIMKHNBD_02202 9.6e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMKHNBD_02203 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIMKHNBD_02206 4.5e-95 hpr K helix_turn_helix multiple antibiotic resistance protein
HIMKHNBD_02207 7.4e-43
HIMKHNBD_02208 1.9e-130 IQ Enoyl-(Acyl carrier protein) reductase
HIMKHNBD_02209 1.7e-54 ykvN K Transcriptional regulator
HIMKHNBD_02210 1.1e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HIMKHNBD_02211 6.6e-61 yobQ K helix_turn_helix, arabinose operon control protein
HIMKHNBD_02212 1.2e-92 yobS K Transcriptional regulator
HIMKHNBD_02213 7.2e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HIMKHNBD_02214 7.1e-92 yobW
HIMKHNBD_02215 8.4e-54 czrA K transcriptional
HIMKHNBD_02216 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HIMKHNBD_02217 3.6e-91 yozB S membrane
HIMKHNBD_02218 5.2e-139 yocB J Protein required for attachment to host cells
HIMKHNBD_02219 1.6e-93 yocC
HIMKHNBD_02220 1.6e-185 yocD 3.4.17.13 V peptidase S66
HIMKHNBD_02222 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
HIMKHNBD_02223 0.0 recQ 3.6.4.12 L DNA helicase
HIMKHNBD_02224 7.8e-71 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIMKHNBD_02226 8.6e-55 dksA T general stress protein
HIMKHNBD_02227 1e-09 yocL
HIMKHNBD_02228 7.5e-09
HIMKHNBD_02229 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
HIMKHNBD_02230 3.8e-44 yozN
HIMKHNBD_02231 8.5e-37 yocN
HIMKHNBD_02232 2.4e-56 yozO S Bacterial PH domain
HIMKHNBD_02234 1e-30 yozC
HIMKHNBD_02235 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HIMKHNBD_02236 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HIMKHNBD_02237 2.1e-165 sodA 1.15.1.1 P Superoxide dismutase
HIMKHNBD_02238 3.3e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HIMKHNBD_02239 2.3e-160 yocS S -transporter
HIMKHNBD_02240 7.2e-138 S Metallo-beta-lactamase superfamily
HIMKHNBD_02241 1.2e-103 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HIMKHNBD_02242 6e-72 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HIMKHNBD_02243 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HIMKHNBD_02244 9.6e-135 yojO P Von Willebrand factor
HIMKHNBD_02245 4.3e-209 yojO P Von Willebrand factor
HIMKHNBD_02246 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
HIMKHNBD_02247 1.9e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HIMKHNBD_02248 2.6e-225 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HIMKHNBD_02249 6.9e-223 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HIMKHNBD_02250 1.7e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIMKHNBD_02252 6.1e-236 norM V Multidrug efflux pump
HIMKHNBD_02253 2.2e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIMKHNBD_02254 5.6e-126 yojG S deacetylase
HIMKHNBD_02255 3.7e-60 yojF S Protein of unknown function (DUF1806)
HIMKHNBD_02256 1.3e-23
HIMKHNBD_02257 1.4e-107 rarD S -transporter
HIMKHNBD_02258 2.7e-39 rarD S -transporter
HIMKHNBD_02259 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
HIMKHNBD_02261 1.6e-67 yodA S tautomerase
HIMKHNBD_02262 6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
HIMKHNBD_02263 7.2e-29 yodB K transcriptional
HIMKHNBD_02264 4.5e-106 yodC C nitroreductase
HIMKHNBD_02265 5.7e-109 mhqD S Carboxylesterase
HIMKHNBD_02266 1e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
HIMKHNBD_02267 1.4e-19 S Protein of unknown function (DUF3311)
HIMKHNBD_02268 3.7e-36 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMKHNBD_02269 7.3e-209 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMKHNBD_02270 4.1e-278 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
HIMKHNBD_02271 3.3e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIMKHNBD_02272 2.6e-132 yydK K Transcriptional regulator
HIMKHNBD_02273 7.9e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HIMKHNBD_02274 8.3e-128 yodH Q Methyltransferase
HIMKHNBD_02275 1.9e-21 yodI
HIMKHNBD_02276 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HIMKHNBD_02277 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HIMKHNBD_02279 2.1e-53 yodL S YodL-like
HIMKHNBD_02280 2.3e-102 yodM 3.6.1.27 I Acid phosphatase homologues
HIMKHNBD_02281 6.2e-24 yozD S YozD-like protein
HIMKHNBD_02282 1.7e-125 yodN
HIMKHNBD_02283 5.5e-27 E lactoylglutathione lyase activity
HIMKHNBD_02284 2e-35 yozE S Belongs to the UPF0346 family
HIMKHNBD_02285 9.2e-46 yokU S YokU-like protein, putative antitoxin
HIMKHNBD_02286 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
HIMKHNBD_02287 9.8e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HIMKHNBD_02288 7e-172 yodQ 3.5.1.16 E Acetylornithine deacetylase
HIMKHNBD_02289 4.7e-43 yodQ 3.5.1.16 E Acetylornithine deacetylase
HIMKHNBD_02290 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HIMKHNBD_02291 2.2e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HIMKHNBD_02292 7.1e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIMKHNBD_02293 4.1e-64 yosT L Bacterial transcription activator, effector binding domain
HIMKHNBD_02294 5.6e-283 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HIMKHNBD_02295 1.2e-49 S Domain of unknown function (DUF4870)
HIMKHNBD_02296 2.1e-112 T PhoQ Sensor
HIMKHNBD_02297 6e-105 T PhoQ Sensor
HIMKHNBD_02298 3.2e-127 T Transcriptional regulatory protein, C terminal
HIMKHNBD_02299 8.2e-251 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
HIMKHNBD_02300 8e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HIMKHNBD_02301 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_02302 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_02303 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_02304 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_02305 5.8e-214 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HIMKHNBD_02306 6.4e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HIMKHNBD_02307 7.1e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HIMKHNBD_02308 3.4e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HIMKHNBD_02309 2.8e-222 yxjC EG COG2610 H gluconate symporter and related permeases
HIMKHNBD_02310 1.6e-216 bioI 1.14.14.46 C Cytochrome P450
HIMKHNBD_02311 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HIMKHNBD_02312 4.1e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HIMKHNBD_02313 9e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HIMKHNBD_02314 1.1e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HIMKHNBD_02315 2e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HIMKHNBD_02316 9.6e-68 yngA S membrane
HIMKHNBD_02317 3.1e-156 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HIMKHNBD_02318 3.2e-104 yngC S SNARE associated Golgi protein
HIMKHNBD_02319 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HIMKHNBD_02320 3.1e-139 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HIMKHNBD_02321 5.2e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HIMKHNBD_02322 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HIMKHNBD_02323 5.3e-181 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HIMKHNBD_02324 3.7e-36 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HIMKHNBD_02325 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HIMKHNBD_02326 3.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HIMKHNBD_02327 5.5e-265 yngK T Glycosyl hydrolase-like 10
HIMKHNBD_02328 1.6e-64 yngL S Protein of unknown function (DUF1360)
HIMKHNBD_02329 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
HIMKHNBD_02330 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_02331 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_02332 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_02333 3.9e-32 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMKHNBD_02334 4.3e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
HIMKHNBD_02335 2.5e-39 yhdB S YhdB-like protein
HIMKHNBD_02336 1.1e-53 yhdC S Protein of unknown function (DUF3889)
HIMKHNBD_02337 5.4e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HIMKHNBD_02338 1.6e-73 nsrR K Transcriptional regulator
HIMKHNBD_02339 1.1e-254 ygxB M Conserved TM helix
HIMKHNBD_02340 1.8e-270 ycgB S Stage V sporulation protein R
HIMKHNBD_02341 3.4e-100 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HIMKHNBD_02342 9.4e-116 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HIMKHNBD_02343 2.2e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HIMKHNBD_02344 1.3e-162 citR K Transcriptional regulator
HIMKHNBD_02345 1.6e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
HIMKHNBD_02346 3.9e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMKHNBD_02347 1.2e-250 yhdG E amino acid
HIMKHNBD_02348 2.4e-197 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HIMKHNBD_02349 8.1e-45 yhdK S Sigma-M inhibitor protein
HIMKHNBD_02350 5e-201 yhdL S Sigma factor regulator N-terminal
HIMKHNBD_02351 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HIMKHNBD_02352 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HIMKHNBD_02353 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HIMKHNBD_02354 2.8e-70 cueR K transcriptional
HIMKHNBD_02355 1.9e-225 yhdR 2.6.1.1 E Aminotransferase
HIMKHNBD_02356 9.5e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIMKHNBD_02357 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HIMKHNBD_02358 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIMKHNBD_02359 4.4e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIMKHNBD_02360 1.8e-125 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIMKHNBD_02362 3.5e-205 yhdY M Mechanosensitive ion channel
HIMKHNBD_02363 2.9e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HIMKHNBD_02364 1.1e-155 yheN G deacetylase
HIMKHNBD_02365 9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HIMKHNBD_02366 3e-87 pksA K Transcriptional regulator
HIMKHNBD_02367 6.5e-60 ymcC S Membrane
HIMKHNBD_02368 6.2e-85 T universal stress protein
HIMKHNBD_02370 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HIMKHNBD_02371 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HIMKHNBD_02372 1.8e-110 yheG GM NAD(P)H-binding
HIMKHNBD_02374 1.3e-28 sspB S spore protein
HIMKHNBD_02375 1.7e-36 yheE S Family of unknown function (DUF5342)
HIMKHNBD_02376 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HIMKHNBD_02377 1.3e-212 yheC HJ YheC/D like ATP-grasp
HIMKHNBD_02378 3.6e-205 yheB S Belongs to the UPF0754 family
HIMKHNBD_02379 4.4e-53 yheA S Belongs to the UPF0342 family
HIMKHNBD_02380 1.4e-201 yhaZ L DNA alkylation repair enzyme
HIMKHNBD_02381 4.7e-157 yhaX S haloacid dehalogenase-like hydrolase
HIMKHNBD_02382 2.7e-293 hemZ H coproporphyrinogen III oxidase
HIMKHNBD_02383 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
HIMKHNBD_02384 3.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
HIMKHNBD_02385 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HIMKHNBD_02387 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
HIMKHNBD_02388 2.8e-14 S YhzD-like protein
HIMKHNBD_02389 4.9e-165 yhaQ S ABC transporter, ATP-binding protein
HIMKHNBD_02390 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HIMKHNBD_02391 7.2e-236 yhaO L DNA repair exonuclease
HIMKHNBD_02392 3e-121 yhaN L AAA domain
HIMKHNBD_02393 0.0 yhaN L AAA domain
HIMKHNBD_02394 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HIMKHNBD_02395 1.8e-31 yhaL S Sporulation protein YhaL
HIMKHNBD_02396 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HIMKHNBD_02397 3.3e-30
HIMKHNBD_02398 7e-95 yhaK S Putative zincin peptidase
HIMKHNBD_02399 9.9e-55 yhaI S Protein of unknown function (DUF1878)
HIMKHNBD_02400 8.6e-113 hpr K Negative regulator of protease production and sporulation
HIMKHNBD_02401 6.2e-39 yhaH S YtxH-like protein
HIMKHNBD_02402 2e-17
HIMKHNBD_02403 1.4e-76 trpP S Tryptophan transporter TrpP
HIMKHNBD_02404 3.8e-72 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HIMKHNBD_02405 1.9e-113 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HIMKHNBD_02406 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HIMKHNBD_02407 1.1e-135 ecsA V transporter (ATP-binding protein)
HIMKHNBD_02408 1.9e-220 ecsB U ABC transporter
HIMKHNBD_02409 7.5e-121 ecsC S EcsC protein family
HIMKHNBD_02410 2e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HIMKHNBD_02411 6.2e-244 yhfA C membrane
HIMKHNBD_02412 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HIMKHNBD_02413 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HIMKHNBD_02414 9.5e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HIMKHNBD_02415 9.5e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HIMKHNBD_02416 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HIMKHNBD_02417 3.2e-101 yhgD K Transcriptional regulator
HIMKHNBD_02418 2e-97 yhgE S YhgE Pip N-terminal domain protein
HIMKHNBD_02419 1.9e-151 yhgE S YhgE Pip N-terminal domain protein
HIMKHNBD_02420 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIMKHNBD_02423 3.2e-89 ysnB S Phosphoesterase
HIMKHNBD_02424 4.2e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HIMKHNBD_02425 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HIMKHNBD_02426 5.3e-198 gerM S COG5401 Spore germination protein
HIMKHNBD_02427 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HIMKHNBD_02428 2.1e-73 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HIMKHNBD_02429 2e-30 gerE K Transcriptional regulator
HIMKHNBD_02430 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HIMKHNBD_02431 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HIMKHNBD_02432 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HIMKHNBD_02433 4.8e-108 sdhC C succinate dehydrogenase
HIMKHNBD_02434 2e-79 yslB S Protein of unknown function (DUF2507)
HIMKHNBD_02435 5.7e-192 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HIMKHNBD_02436 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIMKHNBD_02437 2.5e-52 trxA O Belongs to the thioredoxin family
HIMKHNBD_02438 3e-181 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HIMKHNBD_02439 1.2e-93 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HIMKHNBD_02440 1.6e-177 etfA C Electron transfer flavoprotein
HIMKHNBD_02441 8.2e-137 etfB C Electron transfer flavoprotein
HIMKHNBD_02442 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HIMKHNBD_02443 2.7e-103 fadR K Transcriptional regulator
HIMKHNBD_02444 1.4e-283 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HIMKHNBD_02445 8.2e-21 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HIMKHNBD_02446 9.4e-90 ywbB S Protein of unknown function (DUF2711)
HIMKHNBD_02447 4.7e-67 yshE S membrane
HIMKHNBD_02448 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIMKHNBD_02449 2.6e-197 polX L COG1796 DNA polymerase IV (family X)
HIMKHNBD_02450 1.8e-93 polX L COG1796 DNA polymerase IV (family X)
HIMKHNBD_02451 6.6e-64 cvpA S membrane protein, required for colicin V production
HIMKHNBD_02452 1e-10 cvpA S membrane protein, required for colicin V production
HIMKHNBD_02453 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HIMKHNBD_02454 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIMKHNBD_02455 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIMKHNBD_02456 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIMKHNBD_02457 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIMKHNBD_02458 2e-32 sspI S Belongs to the SspI family
HIMKHNBD_02459 2.7e-202 ysfB KT regulator
HIMKHNBD_02460 4.5e-258 glcD 1.1.3.15 C FAD binding domain
HIMKHNBD_02461 6.4e-254 glcF C Glycolate oxidase
HIMKHNBD_02462 0.0 cstA T Carbon starvation protein
HIMKHNBD_02463 3.9e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HIMKHNBD_02464 1.2e-144 araQ G transport system permease
HIMKHNBD_02465 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
HIMKHNBD_02466 2.9e-251 araN G carbohydrate transport
HIMKHNBD_02467 1.8e-223 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HIMKHNBD_02468 7.8e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HIMKHNBD_02469 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HIMKHNBD_02470 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HIMKHNBD_02471 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HIMKHNBD_02472 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HIMKHNBD_02473 2.1e-117 ysdC G COG1363 Cellulase M and related proteins
HIMKHNBD_02474 1.7e-77 ysdC G COG1363 Cellulase M and related proteins
HIMKHNBD_02475 1.9e-65 ysdB S Sigma-w pathway protein YsdB
HIMKHNBD_02476 2.6e-42 ysdA S Membrane
HIMKHNBD_02477 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIMKHNBD_02478 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HIMKHNBD_02479 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIMKHNBD_02480 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HIMKHNBD_02481 2.9e-38 lrgA S effector of murein hydrolase LrgA
HIMKHNBD_02482 1.2e-129 lytT T COG3279 Response regulator of the LytR AlgR family
HIMKHNBD_02483 0.0 lytS 2.7.13.3 T Histidine kinase
HIMKHNBD_02484 1.5e-149 ysaA S HAD-hyrolase-like
HIMKHNBD_02485 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIMKHNBD_02486 6.7e-153 ytxC S YtxC-like family
HIMKHNBD_02487 2.1e-106 ytxB S SNARE associated Golgi protein
HIMKHNBD_02488 9.5e-172 dnaI L Primosomal protein DnaI
HIMKHNBD_02489 3.1e-251 dnaB L Membrane attachment protein
HIMKHNBD_02490 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIMKHNBD_02491 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HIMKHNBD_02492 1.6e-126 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIMKHNBD_02493 9.8e-59 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIMKHNBD_02494 2e-67 ytcD K Transcriptional regulator
HIMKHNBD_02495 1.3e-205 ytbD EGP Major facilitator Superfamily
HIMKHNBD_02496 7.6e-160 ytbE S reductase
HIMKHNBD_02497 2.2e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIMKHNBD_02498 2.1e-106 ytaF P Probably functions as a manganese efflux pump
HIMKHNBD_02499 3.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HIMKHNBD_02500 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIMKHNBD_02501 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HIMKHNBD_02502 1.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMKHNBD_02503 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HIMKHNBD_02504 1.2e-241 icd 1.1.1.42 C isocitrate
HIMKHNBD_02505 4.3e-61 citZ 2.3.3.1 C Belongs to the citrate synthase family
HIMKHNBD_02506 9.5e-136 citZ 2.3.3.1 C Belongs to the citrate synthase family
HIMKHNBD_02507 5.7e-42
HIMKHNBD_02508 1.1e-53 yusN M Coat F domain
HIMKHNBD_02509 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
HIMKHNBD_02510 4e-287 yusP P Major facilitator superfamily
HIMKHNBD_02511 1e-154 ywbI2 K Transcriptional regulator
HIMKHNBD_02512 4.2e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HIMKHNBD_02513 2.4e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIMKHNBD_02514 3.3e-39 yusU S Protein of unknown function (DUF2573)
HIMKHNBD_02515 3.1e-150 yusV 3.6.3.34 HP ABC transporter
HIMKHNBD_02516 7.7e-45 S YusW-like protein
HIMKHNBD_02517 0.0 pepF2 E COG1164 Oligoendopeptidase F
HIMKHNBD_02518 1.5e-147 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMKHNBD_02519 4e-78 dps P Belongs to the Dps family
HIMKHNBD_02520 5e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIMKHNBD_02521 5.7e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMKHNBD_02522 2.2e-249 cssS 2.7.13.3 T PhoQ Sensor
HIMKHNBD_02523 3.4e-24
HIMKHNBD_02524 2.9e-157 yuxN K Transcriptional regulator
HIMKHNBD_02525 8.7e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HIMKHNBD_02526 6.6e-24 S Protein of unknown function (DUF3970)
HIMKHNBD_02527 1.2e-258 gerAA EG Spore germination protein
HIMKHNBD_02528 3.6e-186 gerAB E Spore germination protein
HIMKHNBD_02529 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
HIMKHNBD_02530 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMKHNBD_02531 2.3e-193 vraS 2.7.13.3 T Histidine kinase
HIMKHNBD_02532 1.9e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HIMKHNBD_02533 2.7e-89 liaG S Putative adhesin
HIMKHNBD_02534 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HIMKHNBD_02535 9e-44 liaI S membrane
HIMKHNBD_02536 2.2e-227 yvqJ EGP Major facilitator Superfamily
HIMKHNBD_02537 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
HIMKHNBD_02538 1.2e-219 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HIMKHNBD_02539 2.7e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMKHNBD_02540 1.6e-166 yvrC P ABC transporter substrate-binding protein
HIMKHNBD_02541 4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMKHNBD_02542 1.1e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
HIMKHNBD_02543 0.0 T PhoQ Sensor
HIMKHNBD_02544 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMKHNBD_02545 1.1e-36
HIMKHNBD_02546 3.8e-102 yvrI K RNA polymerase
HIMKHNBD_02547 6.1e-15 S YvrJ protein family
HIMKHNBD_02548 3.9e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
HIMKHNBD_02549 9.3e-66 yvrL S Regulatory protein YrvL
HIMKHNBD_02550 4.1e-147 fhuC 3.6.3.34 HP ABC transporter
HIMKHNBD_02551 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMKHNBD_02552 4.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMKHNBD_02553 7.6e-177 fhuD P ABC transporter
HIMKHNBD_02554 7e-127 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HIMKHNBD_02555 1.4e-235 yvsH E Arginine ornithine antiporter
HIMKHNBD_02556 5.2e-13 S Small spore protein J (Spore_SspJ)
HIMKHNBD_02557 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HIMKHNBD_02558 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HIMKHNBD_02559 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HIMKHNBD_02560 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HIMKHNBD_02561 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
HIMKHNBD_02562 8.6e-114 yfiK K Regulator
HIMKHNBD_02563 2.1e-178 T Histidine kinase
HIMKHNBD_02564 1.6e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
HIMKHNBD_02565 1.3e-191 yfiM V ABC-2 type transporter
HIMKHNBD_02566 6.8e-196 yfiN V COG0842 ABC-type multidrug transport system, permease component
HIMKHNBD_02567 1.5e-155 yvgN S reductase
HIMKHNBD_02568 2.7e-85 yvgO
HIMKHNBD_02569 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HIMKHNBD_02570 1e-248 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HIMKHNBD_02571 2.3e-51 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HIMKHNBD_02573 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HIMKHNBD_02574 0.0 helD 3.6.4.12 L DNA helicase
HIMKHNBD_02575 2.9e-97 yvgT S membrane
HIMKHNBD_02576 2e-141 S Metallo-peptidase family M12
HIMKHNBD_02577 6e-73 bdbC O Required for disulfide bond formation in some proteins
HIMKHNBD_02578 4.6e-90 bdbD O Thioredoxin
HIMKHNBD_02579 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HIMKHNBD_02580 0.0 copA 3.6.3.54 P P-type ATPase
HIMKHNBD_02581 2.6e-29 copZ P Heavy-metal-associated domain
HIMKHNBD_02582 3.7e-48 csoR S transcriptional
HIMKHNBD_02583 1.1e-192 yvaA 1.1.1.371 S Oxidoreductase
HIMKHNBD_02584 1.8e-22 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIMKHNBD_02585 1.8e-75 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIMKHNBD_02586 7.5e-77 ctsR K Belongs to the CtsR family
HIMKHNBD_02587 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HIMKHNBD_02588 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HIMKHNBD_02589 1.2e-39 clpC O Belongs to the ClpA ClpB family
HIMKHNBD_02590 0.0 clpC O Belongs to the ClpA ClpB family
HIMKHNBD_02591 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIMKHNBD_02592 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HIMKHNBD_02593 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HIMKHNBD_02594 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HIMKHNBD_02595 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HIMKHNBD_02596 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIMKHNBD_02597 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
HIMKHNBD_02598 5.3e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIMKHNBD_02599 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HIMKHNBD_02600 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIMKHNBD_02601 4.2e-89 yacP S RNA-binding protein containing a PIN domain
HIMKHNBD_02602 8.9e-116 sigH K Belongs to the sigma-70 factor family
HIMKHNBD_02603 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIMKHNBD_02604 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HIMKHNBD_02605 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIMKHNBD_02606 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIMKHNBD_02607 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIMKHNBD_02608 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIMKHNBD_02609 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
HIMKHNBD_02610 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMKHNBD_02611 6.3e-157 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMKHNBD_02612 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMKHNBD_02613 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HIMKHNBD_02614 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIMKHNBD_02615 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HIMKHNBD_02616 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HIMKHNBD_02617 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIMKHNBD_02618 1.8e-181 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HIMKHNBD_02619 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HIMKHNBD_02620 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIMKHNBD_02621 3e-105 rplD J Forms part of the polypeptide exit tunnel
HIMKHNBD_02622 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIMKHNBD_02623 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIMKHNBD_02624 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIMKHNBD_02625 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIMKHNBD_02626 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIMKHNBD_02627 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIMKHNBD_02628 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HIMKHNBD_02629 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIMKHNBD_02630 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIMKHNBD_02631 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIMKHNBD_02632 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIMKHNBD_02633 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIMKHNBD_02634 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIMKHNBD_02635 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIMKHNBD_02636 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIMKHNBD_02637 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIMKHNBD_02638 1.9e-23 rpmD J Ribosomal protein L30
HIMKHNBD_02639 4.1e-72 rplO J binds to the 23S rRNA
HIMKHNBD_02640 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIMKHNBD_02641 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIMKHNBD_02642 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
HIMKHNBD_02643 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIMKHNBD_02644 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HIMKHNBD_02645 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIMKHNBD_02646 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIMKHNBD_02647 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMKHNBD_02648 4.7e-58 rplQ J Ribosomal protein L17
HIMKHNBD_02649 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMKHNBD_02650 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMKHNBD_02651 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMKHNBD_02652 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIMKHNBD_02653 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIMKHNBD_02654 6.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HIMKHNBD_02655 3.1e-144 ybaJ Q Methyltransferase domain
HIMKHNBD_02656 1.2e-82 yizA S Damage-inducible protein DinB
HIMKHNBD_02657 1.4e-77 ybaK S Protein of unknown function (DUF2521)
HIMKHNBD_02658 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMKHNBD_02659 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HIMKHNBD_02660 1.7e-75 gerD
HIMKHNBD_02661 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HIMKHNBD_02662 1.8e-131 pdaB 3.5.1.104 G Polysaccharide deacetylase
HIMKHNBD_02663 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMKHNBD_02666 2e-08
HIMKHNBD_02669 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMKHNBD_02670 3.1e-96 thiT S Thiamine transporter protein (Thia_YuaJ)
HIMKHNBD_02671 1.7e-178 yuaG 3.4.21.72 S protein conserved in bacteria
HIMKHNBD_02672 7.3e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HIMKHNBD_02673 2e-72 yuaE S DinB superfamily
HIMKHNBD_02674 2.5e-109 yuaD S MOSC domain
HIMKHNBD_02675 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
HIMKHNBD_02676 1.9e-272 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HIMKHNBD_02677 8.6e-96 yuaC K Belongs to the GbsR family
HIMKHNBD_02678 3e-93 yuaB
HIMKHNBD_02679 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
HIMKHNBD_02680 1.5e-144 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIMKHNBD_02681 9.4e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HIMKHNBD_02682 1.4e-118 G Cupin
HIMKHNBD_02683 2.2e-51 yjcN
HIMKHNBD_02685 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HIMKHNBD_02686 2.9e-194 yubA S transporter activity
HIMKHNBD_02687 1.4e-184 ygjR S Oxidoreductase
HIMKHNBD_02688 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HIMKHNBD_02690 1.8e-190 mcpA NT chemotaxis protein
HIMKHNBD_02691 6e-224 mcpA NT chemotaxis protein
HIMKHNBD_02692 1e-231 mcpA NT chemotaxis protein
HIMKHNBD_02693 2.4e-220 mcpA NT chemotaxis protein
HIMKHNBD_02694 2.2e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HIMKHNBD_02695 1.4e-40
HIMKHNBD_02696 1.1e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HIMKHNBD_02697 2e-73 yugU S Uncharacterised protein family UPF0047
HIMKHNBD_02698 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HIMKHNBD_02699 1.9e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HIMKHNBD_02700 8.3e-117 yugP S Zn-dependent protease
HIMKHNBD_02701 3.4e-18
HIMKHNBD_02702 6.7e-27 mstX S Membrane-integrating protein Mistic
HIMKHNBD_02703 2e-180 yugO P COG1226 Kef-type K transport systems
HIMKHNBD_02704 7e-71 yugN S YugN-like family
HIMKHNBD_02706 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
HIMKHNBD_02707 4.5e-80 S NADPH-dependent FMN reductase
HIMKHNBD_02708 5.5e-118 ycaC Q Isochorismatase family
HIMKHNBD_02709 1.4e-228 yugK C Dehydrogenase
HIMKHNBD_02710 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HIMKHNBD_02711 1.8e-34 yuzA S Domain of unknown function (DUF378)
HIMKHNBD_02712 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HIMKHNBD_02713 1.6e-208 yugH 2.6.1.1 E Aminotransferase
HIMKHNBD_02714 2e-83 alaR K Transcriptional regulator
HIMKHNBD_02715 5.5e-155 yugF I Hydrolase
HIMKHNBD_02716 1.4e-40 yugE S Domain of unknown function (DUF1871)
HIMKHNBD_02717 3.3e-222 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HIMKHNBD_02718 1e-42 T PhoQ Sensor
HIMKHNBD_02719 5.5e-170 T PhoQ Sensor
HIMKHNBD_02720 7.7e-67 kapB G Kinase associated protein B
HIMKHNBD_02721 4e-118 kapD L the KinA pathway to sporulation
HIMKHNBD_02722 4.5e-185 yuxJ EGP Major facilitator Superfamily
HIMKHNBD_02723 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HIMKHNBD_02724 2.2e-72 yuxK S protein conserved in bacteria
HIMKHNBD_02725 1e-70 yufK S Family of unknown function (DUF5366)
HIMKHNBD_02726 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HIMKHNBD_02727 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
HIMKHNBD_02728 6e-194 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HIMKHNBD_02729 6.1e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HIMKHNBD_02730 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
HIMKHNBD_02731 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HIMKHNBD_02732 2.3e-12
HIMKHNBD_02733 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HIMKHNBD_02734 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIMKHNBD_02735 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIMKHNBD_02736 3.4e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIMKHNBD_02737 8.5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIMKHNBD_02738 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIMKHNBD_02739 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HIMKHNBD_02740 1.1e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
HIMKHNBD_02741 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMKHNBD_02742 1e-125 comP 2.7.13.3 T Histidine kinase
HIMKHNBD_02743 6.4e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HIMKHNBD_02744 7.9e-08 S YyzF-like protein
HIMKHNBD_02746 2.8e-213 yycP
HIMKHNBD_02747 2.7e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HIMKHNBD_02748 3.9e-184 C oxidoreductases (related to aryl-alcohol dehydrogenases)
HIMKHNBD_02749 6.9e-86 yycN 2.3.1.128 K Acetyltransferase
HIMKHNBD_02751 2.2e-199 S Histidine kinase
HIMKHNBD_02752 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HIMKHNBD_02753 1.9e-256 rocE E amino acid
HIMKHNBD_02754 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HIMKHNBD_02755 2e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HIMKHNBD_02756 5.9e-145 1.14.11.27 P peptidyl-arginine hydroxylation
HIMKHNBD_02757 1.3e-304 S ABC transporter
HIMKHNBD_02758 4.5e-195 S Major Facilitator Superfamily
HIMKHNBD_02759 9.4e-258
HIMKHNBD_02760 2.7e-188 2.7.7.73, 2.7.7.80 H ThiF family
HIMKHNBD_02761 5.6e-248 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HIMKHNBD_02762 2.1e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMKHNBD_02763 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIMKHNBD_02764 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HIMKHNBD_02765 1.1e-150 yycI S protein conserved in bacteria
HIMKHNBD_02766 7.2e-261 yycH S protein conserved in bacteria
HIMKHNBD_02767 0.0 vicK 2.7.13.3 T Histidine kinase
HIMKHNBD_02768 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMKHNBD_02773 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIMKHNBD_02774 8.5e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMKHNBD_02775 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HIMKHNBD_02776 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HIMKHNBD_02778 1e-16 yycC K YycC-like protein
HIMKHNBD_02779 2.4e-234 M Glycosyltransferase Family 4
HIMKHNBD_02780 1.1e-94 S Ecdysteroid kinase
HIMKHNBD_02781 7.5e-87 S Ecdysteroid kinase
HIMKHNBD_02782 8e-232 S Carbamoyl-phosphate synthase L chain, ATP binding domain
HIMKHNBD_02783 5.1e-243 M Glycosyltransferase Family 4
HIMKHNBD_02784 1.1e-121 S GlcNAc-PI de-N-acetylase
HIMKHNBD_02785 3.8e-122 KLT COG0515 Serine threonine protein kinase
HIMKHNBD_02786 4.9e-73 rplI J binds to the 23S rRNA
HIMKHNBD_02787 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HIMKHNBD_02788 2.2e-94 yybS S membrane
HIMKHNBD_02789 5.1e-52 yybS S membrane
HIMKHNBD_02791 2.1e-83 cotF M Spore coat protein
HIMKHNBD_02792 8.2e-66 ydeP3 K Transcriptional regulator
HIMKHNBD_02793 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HIMKHNBD_02794 1.8e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HIMKHNBD_02795 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
HIMKHNBD_02796 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HIMKHNBD_02797 2.2e-114 K FCD domain
HIMKHNBD_02798 1.8e-71 dinB S PFAM DinB family protein
HIMKHNBD_02799 1e-157 G Major Facilitator Superfamily
HIMKHNBD_02800 2.2e-55 ypaA S Protein of unknown function (DUF1304)
HIMKHNBD_02801 5.6e-115 drgA C nitroreductase
HIMKHNBD_02802 3.9e-32 ydgJ K Winged helix DNA-binding domain
HIMKHNBD_02803 7.9e-28 ydgJ K Winged helix DNA-binding domain
HIMKHNBD_02804 1.5e-150 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HIMKHNBD_02805 1.6e-76 yybA 2.3.1.57 K transcriptional
HIMKHNBD_02806 2.2e-39 yjcF S Acetyltransferase (GNAT) domain
HIMKHNBD_02808 6.4e-162 eaeH M Domain of Unknown Function (DUF1259)
HIMKHNBD_02809 1.7e-64 4.1.1.44 S Carboxymuconolactone decarboxylase family
HIMKHNBD_02810 2.5e-161 K Transcriptional regulator
HIMKHNBD_02811 6.6e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HIMKHNBD_02812 3.2e-101 I Pfam Lipase (class 3)
HIMKHNBD_02813 2.6e-33
HIMKHNBD_02815 1e-292 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
HIMKHNBD_02816 5.2e-218 rafB P LacY proton/sugar symporter
HIMKHNBD_02817 7.3e-183 scrR K transcriptional
HIMKHNBD_02818 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIMKHNBD_02819 6.7e-164 yraN K Transcriptional regulator
HIMKHNBD_02820 1.4e-209 yraM S PrpF protein
HIMKHNBD_02821 4.6e-247 EGP Sugar (and other) transporter
HIMKHNBD_02822 5.3e-11 yvdD 3.2.2.10 S Belongs to the LOG family
HIMKHNBD_02823 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HIMKHNBD_02824 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HIMKHNBD_02825 7.3e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HIMKHNBD_02826 1.3e-90 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HIMKHNBD_02827 1.2e-182 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMKHNBD_02828 8.2e-79 M Ribonuclease
HIMKHNBD_02829 5.7e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HIMKHNBD_02830 4.7e-36 crh G Phosphocarrier protein Chr
HIMKHNBD_02831 5.3e-170 whiA K May be required for sporulation
HIMKHNBD_02832 1.9e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HIMKHNBD_02833 1.1e-166 rapZ S Displays ATPase and GTPase activities
HIMKHNBD_02834 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HIMKHNBD_02835 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIMKHNBD_02836 1.3e-124 usp CBM50 M protein conserved in bacteria
HIMKHNBD_02837 5e-276 S COG0457 FOG TPR repeat
HIMKHNBD_02838 5.2e-190 sasA T Histidine kinase
HIMKHNBD_02839 9.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMKHNBD_02840 1.2e-46
HIMKHNBD_02841 0.0 msbA2 3.6.3.44 V ABC transporter
HIMKHNBD_02842 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HIMKHNBD_02843 1.7e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HIMKHNBD_02844 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HIMKHNBD_02845 4.7e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HIMKHNBD_02846 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HIMKHNBD_02847 1.4e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HIMKHNBD_02848 1.1e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HIMKHNBD_02849 1e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HIMKHNBD_02850 3.5e-137 yvpB NU protein conserved in bacteria
HIMKHNBD_02851 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HIMKHNBD_02852 7e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HIMKHNBD_02853 1.5e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIMKHNBD_02854 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HIMKHNBD_02855 3e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HIMKHNBD_02856 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIMKHNBD_02857 2.3e-133 yvoA K transcriptional
HIMKHNBD_02858 4.4e-103 yxaF K Transcriptional regulator
HIMKHNBD_02859 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HIMKHNBD_02860 1.5e-40 yvlD S Membrane
HIMKHNBD_02861 9.6e-26 pspB KT PspC domain
HIMKHNBD_02862 1.2e-165 yvlB S Putative adhesin
HIMKHNBD_02863 6.1e-49 yvlA
HIMKHNBD_02864 2.2e-32 yvkN
HIMKHNBD_02865 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIMKHNBD_02866 1.8e-201 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIMKHNBD_02867 8.2e-157 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIMKHNBD_02868 7.6e-33 csbA S protein conserved in bacteria
HIMKHNBD_02869 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HIMKHNBD_02870 2e-109 yvkB K Transcriptional regulator
HIMKHNBD_02871 1.9e-226 yvkA EGP Major facilitator Superfamily
HIMKHNBD_02872 3.8e-30 csfB S Inhibitor of sigma-G Gin
HIMKHNBD_02873 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HIMKHNBD_02874 1e-188 yaaN P Belongs to the TelA family
HIMKHNBD_02875 4.9e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HIMKHNBD_02876 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIMKHNBD_02877 7.5e-55 yaaQ S protein conserved in bacteria
HIMKHNBD_02878 1.2e-71 yaaR S protein conserved in bacteria
HIMKHNBD_02879 1.3e-182 holB 2.7.7.7 L DNA polymerase III
HIMKHNBD_02880 8.8e-145 yaaT S stage 0 sporulation protein
HIMKHNBD_02881 7.7e-37 yabA L Involved in initiation control of chromosome replication
HIMKHNBD_02882 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HIMKHNBD_02883 4.7e-48 yazA L endonuclease containing a URI domain
HIMKHNBD_02884 4.7e-132 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIMKHNBD_02885 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HIMKHNBD_02886 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIMKHNBD_02887 3.4e-143 tatD L hydrolase, TatD
HIMKHNBD_02888 2.9e-230 rpfB GH23 T protein conserved in bacteria
HIMKHNBD_02889 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIMKHNBD_02890 1.1e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIMKHNBD_02891 8.4e-146 yabG S peptidase
HIMKHNBD_02892 7.8e-39 veg S protein conserved in bacteria
HIMKHNBD_02893 2.9e-27 sspF S DNA topological change
HIMKHNBD_02894 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HIMKHNBD_02895 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HIMKHNBD_02896 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HIMKHNBD_02897 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HIMKHNBD_02898 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIMKHNBD_02899 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIMKHNBD_02900 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HIMKHNBD_02901 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIMKHNBD_02902 3.7e-40 yabK S Peptide ABC transporter permease
HIMKHNBD_02903 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIMKHNBD_02904 6.2e-91 spoVT K stage V sporulation protein
HIMKHNBD_02905 1.6e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMKHNBD_02906 1.8e-273 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HIMKHNBD_02907 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HIMKHNBD_02908 1.9e-49 yabP S Sporulation protein YabP
HIMKHNBD_02909 2.9e-103 yabQ S spore cortex biosynthesis protein
HIMKHNBD_02910 1.4e-52 divIC D Septum formation initiator
HIMKHNBD_02911 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HIMKHNBD_02914 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HIMKHNBD_02915 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
HIMKHNBD_02916 6.8e-184 KLT serine threonine protein kinase
HIMKHNBD_02917 8.8e-270 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIMKHNBD_02918 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HIMKHNBD_02919 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIMKHNBD_02920 3.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HIMKHNBD_02921 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HIMKHNBD_02922 3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HIMKHNBD_02923 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HIMKHNBD_02924 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HIMKHNBD_02925 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HIMKHNBD_02926 6.5e-162 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HIMKHNBD_02927 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HIMKHNBD_02928 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HIMKHNBD_02929 2.4e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HIMKHNBD_02930 4.5e-29 yazB K transcriptional
HIMKHNBD_02931 1.7e-187 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIMKHNBD_02932 3.7e-230 oppA5 E PFAM extracellular solute-binding protein family 5
HIMKHNBD_02933 9.8e-148 appB P Binding-protein-dependent transport system inner membrane component
HIMKHNBD_02934 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMKHNBD_02935 3.7e-134 oppD3 P Belongs to the ABC transporter superfamily
HIMKHNBD_02936 1.2e-132 oppF3 E Belongs to the ABC transporter superfamily
HIMKHNBD_02937 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HIMKHNBD_02938 3.7e-90 S Amidohydrolase
HIMKHNBD_02939 7.8e-48 S Amidohydrolase
HIMKHNBD_02940 1.6e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HIMKHNBD_02941 5e-179 ssuA M Sulfonate ABC transporter
HIMKHNBD_02942 1.3e-143 ssuC P ABC transporter (permease)
HIMKHNBD_02943 3.8e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HIMKHNBD_02944 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIMKHNBD_02945 8.6e-81 ygaO
HIMKHNBD_02946 4.8e-23 K Transcriptional regulator
HIMKHNBD_02948 3.2e-107 yhzB S B3/4 domain
HIMKHNBD_02949 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HIMKHNBD_02950 2e-172 yhbB S Putative amidase domain
HIMKHNBD_02951 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIMKHNBD_02952 3e-108 yhbD K Protein of unknown function (DUF4004)
HIMKHNBD_02953 4.7e-62 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HIMKHNBD_02954 9.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HIMKHNBD_02956 0.0 prkA T Ser protein kinase
HIMKHNBD_02957 3.9e-215 yhbH S Belongs to the UPF0229 family
HIMKHNBD_02958 4.6e-74 yhbI K DNA-binding transcription factor activity
HIMKHNBD_02959 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
HIMKHNBD_02960 8.4e-285 yhcA EGP Major facilitator Superfamily
HIMKHNBD_02961 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
HIMKHNBD_02962 3.8e-55 yhcC
HIMKHNBD_02963 2.1e-52
HIMKHNBD_02964 2.8e-61 yhcF K Transcriptional regulator
HIMKHNBD_02965 4.8e-123 yhcG V ABC transporter, ATP-binding protein
HIMKHNBD_02966 1.2e-166 yhcH V ABC transporter, ATP-binding protein
HIMKHNBD_02967 8.2e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HIMKHNBD_02968 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
HIMKHNBD_02969 2.8e-143 metQ M Belongs to the nlpA lipoprotein family
HIMKHNBD_02970 6.7e-185 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HIMKHNBD_02971 4.3e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIMKHNBD_02972 2.5e-53 yhcM
HIMKHNBD_02973 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIMKHNBD_02974 2.2e-160 yhcP
HIMKHNBD_02975 8.4e-114 yhcQ M Spore coat protein
HIMKHNBD_02976 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
HIMKHNBD_02977 1.7e-105 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HIMKHNBD_02978 9e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIMKHNBD_02979 1.3e-69 yhcU S Family of unknown function (DUF5365)
HIMKHNBD_02980 9.9e-68 yhcV S COG0517 FOG CBS domain
HIMKHNBD_02981 4.9e-125 yhcW 5.4.2.6 S hydrolase
HIMKHNBD_02982 4.4e-35 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HIMKHNBD_02983 2.5e-258 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HIMKHNBD_02984 2.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIMKHNBD_02985 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HIMKHNBD_02986 7.7e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HIMKHNBD_02987 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIMKHNBD_02988 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HIMKHNBD_02989 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HIMKHNBD_02990 4.2e-12
HIMKHNBD_02992 2.9e-75
HIMKHNBD_02993 1e-99
HIMKHNBD_02994 1.8e-38
HIMKHNBD_02995 2.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
HIMKHNBD_02998 2.5e-22 ydaT
HIMKHNBD_02999 2.6e-17 yvaE P Small Multidrug Resistance protein
HIMKHNBD_03000 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HIMKHNBD_03003 3.4e-58 ydbB G Cupin domain
HIMKHNBD_03004 8.5e-60 ydbC S Domain of unknown function (DUF4937
HIMKHNBD_03005 1.2e-154 ydbD P Catalase
HIMKHNBD_03006 6.5e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HIMKHNBD_03007 3.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HIMKHNBD_03008 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
HIMKHNBD_03009 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIMKHNBD_03010 4e-158 ydbI S AI-2E family transporter
HIMKHNBD_03011 2.3e-170 ydbJ V ABC transporter, ATP-binding protein
HIMKHNBD_03012 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HIMKHNBD_03013 4.6e-52 ydbL
HIMKHNBD_03014 1.5e-203 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HIMKHNBD_03015 1.5e-10 S Fur-regulated basic protein B
HIMKHNBD_03016 5.8e-09 S Fur-regulated basic protein A
HIMKHNBD_03017 3.8e-117 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIMKHNBD_03018 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HIMKHNBD_03019 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HIMKHNBD_03020 3.5e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIMKHNBD_03021 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HIMKHNBD_03022 5.1e-60 ydbS S Bacterial PH domain
HIMKHNBD_03023 6.5e-260 ydbT S Membrane
HIMKHNBD_03024 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HIMKHNBD_03025 1.5e-56 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIMKHNBD_03026 9.3e-181 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HIMKHNBD_03027 5.8e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIMKHNBD_03028 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HIMKHNBD_03029 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HIMKHNBD_03030 2.3e-145 rsbR T Positive regulator of sigma-B
HIMKHNBD_03031 1.8e-57 rsbS T antagonist
HIMKHNBD_03032 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HIMKHNBD_03033 6.6e-187 rsbU 3.1.3.3 KT phosphatase
HIMKHNBD_03034 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HIMKHNBD_03035 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HIMKHNBD_03036 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMKHNBD_03037 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HIMKHNBD_03038 0.0 yhgF K COG2183 Transcriptional accessory protein
HIMKHNBD_03039 1.7e-14
HIMKHNBD_03040 4.3e-58 ydcK S Belongs to the SprT family
HIMKHNBD_03048 1.1e-95 ywrO S Flavodoxin-like fold
HIMKHNBD_03049 2.8e-149 S Serine aminopeptidase, S33
HIMKHNBD_03050 5.7e-229 proP EGP Transporter
HIMKHNBD_03051 3.8e-136 I esterase
HIMKHNBD_03052 4.8e-46 ohrB O OsmC-like protein
HIMKHNBD_03053 1.4e-48 ohrR K Transcriptional regulator
HIMKHNBD_03054 2e-71 ywnA K Transcriptional regulator
HIMKHNBD_03055 2.7e-109 ywnB S NAD(P)H-binding
HIMKHNBD_03056 1.4e-30 cspL K Cold shock
HIMKHNBD_03057 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIMKHNBD_03058 1.1e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HIMKHNBD_03059 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HIMKHNBD_03060 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIMKHNBD_03061 2.6e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HIMKHNBD_03063 7.4e-253 araE EGP Major facilitator Superfamily
HIMKHNBD_03064 5.5e-203 araR K transcriptional
HIMKHNBD_03065 8.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMKHNBD_03067 2.4e-156 yvbU K Transcriptional regulator
HIMKHNBD_03068 1.7e-157 yvbV EG EamA-like transporter family
HIMKHNBD_03069 3.8e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HIMKHNBD_03071 1.5e-150 ybbH_1 K RpiR family transcriptional regulator
HIMKHNBD_03072 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
HIMKHNBD_03073 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
HIMKHNBD_03074 7.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HIMKHNBD_03075 6.2e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HIMKHNBD_03076 4.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HIMKHNBD_03077 1.5e-217 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIMKHNBD_03078 1.5e-119 yvfI K COG2186 Transcriptional regulators
HIMKHNBD_03079 1.4e-303 yvfH C L-lactate permease
HIMKHNBD_03080 7.2e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HIMKHNBD_03081 2.7e-32 yvfG S YvfG protein
HIMKHNBD_03082 9.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
HIMKHNBD_03083 9e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HIMKHNBD_03084 5.8e-51 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HIMKHNBD_03085 3.7e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HIMKHNBD_03086 1.6e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMKHNBD_03087 1.7e-193 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMKHNBD_03088 2.2e-204 epsI GM pyruvyl transferase
HIMKHNBD_03089 1.9e-192 epsH GT2 S Glycosyltransferase like family 2
HIMKHNBD_03090 7.7e-205 epsG S EpsG family
HIMKHNBD_03091 5.1e-212 epsF GT4 M Glycosyl transferases group 1
HIMKHNBD_03092 9.9e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMKHNBD_03093 4.8e-218 epsD GT4 M Glycosyl transferase 4-like
HIMKHNBD_03094 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HIMKHNBD_03095 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HIMKHNBD_03096 4.6e-118 ywqC M biosynthesis protein
HIMKHNBD_03097 1.9e-77 slr K transcriptional
HIMKHNBD_03098 8.4e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HIMKHNBD_03100 3.7e-96 ywjB H RibD C-terminal domain
HIMKHNBD_03101 1.5e-112 yyaS S Membrane
HIMKHNBD_03102 3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMKHNBD_03103 1.6e-93 padC Q Phenolic acid decarboxylase
HIMKHNBD_03104 5.9e-16 S Protein of unknown function (DUF1433)
HIMKHNBD_03105 7.3e-300 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIMKHNBD_03106 3.9e-44 ylxP S protein conserved in bacteria
HIMKHNBD_03107 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIMKHNBD_03108 3.6e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIMKHNBD_03109 6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HIMKHNBD_03110 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIMKHNBD_03111 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HIMKHNBD_03112 3e-170 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HIMKHNBD_03113 1.2e-233 pepR S Belongs to the peptidase M16 family
HIMKHNBD_03114 2.6e-42 ymxH S YlmC YmxH family
HIMKHNBD_03115 4.7e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HIMKHNBD_03116 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HIMKHNBD_03117 1.2e-121 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIMKHNBD_03118 9e-59 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIMKHNBD_03119 2.1e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HIMKHNBD_03120 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIMKHNBD_03121 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIMKHNBD_03122 2.3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HIMKHNBD_03123 6.3e-31 S YlzJ-like protein
HIMKHNBD_03124 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HIMKHNBD_03125 1.2e-132 ymfC K Transcriptional regulator
HIMKHNBD_03126 3e-227 ymfD EGP Major facilitator Superfamily
HIMKHNBD_03127 2.5e-59 K helix_turn_helix multiple antibiotic resistance protein
HIMKHNBD_03128 0.0 ydgH S drug exporters of the RND superfamily
HIMKHNBD_03129 1.3e-235 ymfF S Peptidase M16
HIMKHNBD_03130 8.6e-201 ymfH S zinc protease
HIMKHNBD_03131 1.1e-28 ymfH S zinc protease
HIMKHNBD_03132 1.2e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HIMKHNBD_03133 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
HIMKHNBD_03134 1e-142 ymfK S Protein of unknown function (DUF3388)
HIMKHNBD_03135 2.4e-124 ymfM S protein conserved in bacteria
HIMKHNBD_03136 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIMKHNBD_03137 2.8e-210 cinA 3.5.1.42 S Belongs to the CinA family
HIMKHNBD_03138 1.3e-151 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIMKHNBD_03139 2e-27 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIMKHNBD_03140 1.1e-193 pbpX V Beta-lactamase
HIMKHNBD_03141 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
HIMKHNBD_03142 4.9e-153 ymdB S protein conserved in bacteria
HIMKHNBD_03143 1.2e-36 spoVS S Stage V sporulation protein S
HIMKHNBD_03144 4.8e-196 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HIMKHNBD_03145 7.4e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HIMKHNBD_03146 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HIMKHNBD_03147 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HIMKHNBD_03148 1.7e-88 cotE S Spore coat protein
HIMKHNBD_03149 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIMKHNBD_03150 2.9e-105 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIMKHNBD_03151 2.6e-274 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HIMKHNBD_03152 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HIMKHNBD_03153 3.6e-285 hutH 4.3.1.3 E Histidine ammonia-lyase
HIMKHNBD_03154 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HIMKHNBD_03155 6.3e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HIMKHNBD_03156 3.2e-175 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HIMKHNBD_03157 3.7e-252 lysP E amino acid
HIMKHNBD_03158 8.7e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HIMKHNBD_03159 1.2e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIMKHNBD_03160 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HIMKHNBD_03161 8.1e-171 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HIMKHNBD_03162 2.6e-149 yidA S hydrolases of the HAD superfamily
HIMKHNBD_03166 8.4e-23 yxeD
HIMKHNBD_03167 1.3e-34
HIMKHNBD_03168 4.1e-178 fhuD P Periplasmic binding protein
HIMKHNBD_03169 1.3e-57 yxeA S Protein of unknown function (DUF1093)
HIMKHNBD_03170 0.0 yxdM V ABC transporter (permease)
HIMKHNBD_03171 3.6e-140 yxdL V ABC transporter, ATP-binding protein
HIMKHNBD_03172 2.5e-175 T PhoQ Sensor
HIMKHNBD_03173 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMKHNBD_03174 1.1e-156 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HIMKHNBD_03175 1.9e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HIMKHNBD_03176 3.3e-166 iolH G Xylose isomerase-like TIM barrel
HIMKHNBD_03177 2.6e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HIMKHNBD_03178 6.7e-232 iolF EGP Major facilitator Superfamily
HIMKHNBD_03179 3.4e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HIMKHNBD_03180 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HIMKHNBD_03181 2.7e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HIMKHNBD_03182 1.6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HIMKHNBD_03183 1.8e-278 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIMKHNBD_03184 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
HIMKHNBD_03185 1.2e-174 iolS C Aldo keto reductase
HIMKHNBD_03186 4.3e-245 csbC EGP Major facilitator Superfamily
HIMKHNBD_03187 0.0 htpG O Molecular chaperone. Has ATPase activity
HIMKHNBD_03189 1.8e-150 IQ Enoyl-(Acyl carrier protein) reductase
HIMKHNBD_03190 2.3e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMKHNBD_03191 4.5e-200 desK 2.7.13.3 T Histidine kinase
HIMKHNBD_03192 9.6e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HIMKHNBD_03193 1.2e-213 yxbF K Bacterial regulatory proteins, tetR family
HIMKHNBD_03194 1.2e-145 yjbA S Belongs to the UPF0736 family
HIMKHNBD_03195 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HIMKHNBD_03196 0.0 oppA E ABC transporter substrate-binding protein
HIMKHNBD_03197 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMKHNBD_03198 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMKHNBD_03199 2.7e-202 oppD P Belongs to the ABC transporter superfamily
HIMKHNBD_03200 2.3e-170 oppF E Belongs to the ABC transporter superfamily
HIMKHNBD_03201 9.8e-230 S Putative glycosyl hydrolase domain
HIMKHNBD_03202 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMKHNBD_03203 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIMKHNBD_03204 4.7e-109 yjbE P Integral membrane protein TerC family
HIMKHNBD_03205 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HIMKHNBD_03206 7.1e-217 yjbF S Competence protein
HIMKHNBD_03207 0.0 pepF E oligoendopeptidase F
HIMKHNBD_03208 5.8e-19
HIMKHNBD_03209 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HIMKHNBD_03210 4.8e-72 yjbI S Bacterial-like globin
HIMKHNBD_03211 1.2e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HIMKHNBD_03212 3.1e-96 yjbK S protein conserved in bacteria
HIMKHNBD_03213 8.6e-60 yjbL S Belongs to the UPF0738 family
HIMKHNBD_03214 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
HIMKHNBD_03215 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIMKHNBD_03216 3.7e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIMKHNBD_03217 4.4e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HIMKHNBD_03218 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HIMKHNBD_03219 9.9e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HIMKHNBD_03220 7.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HIMKHNBD_03221 9.5e-211 thiO 1.4.3.19 E Glycine oxidase
HIMKHNBD_03222 6.7e-30 thiS H Thiamine biosynthesis
HIMKHNBD_03223 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HIMKHNBD_03224 1.1e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HIMKHNBD_03225 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIMKHNBD_03226 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HIMKHNBD_03227 3.6e-81 yjbX S Spore coat protein
HIMKHNBD_03228 6.7e-83 cotZ S Spore coat protein
HIMKHNBD_03229 4.6e-93 cotY S Spore coat protein Z
HIMKHNBD_03230 2.1e-25 cotX S Spore Coat Protein X and V domain
HIMKHNBD_03231 7.4e-16 cotW
HIMKHNBD_03232 1.4e-52 cotV S Spore Coat Protein X and V domain
HIMKHNBD_03233 9.6e-56 yjcA S Protein of unknown function (DUF1360)
HIMKHNBD_03237 3.8e-38 spoVIF S Stage VI sporulation protein F
HIMKHNBD_03238 0.0 yjcD 3.6.4.12 L DNA helicase
HIMKHNBD_03239 2.4e-15
HIMKHNBD_03240 1.4e-141 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HIMKHNBD_03241 5.7e-124 S ABC-2 type transporter
HIMKHNBD_03242 1.3e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
HIMKHNBD_03243 2.7e-35 K SpoVT / AbrB like domain
HIMKHNBD_03245 2.6e-22 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMKHNBD_03246 3.1e-40 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMKHNBD_03247 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HIMKHNBD_03248 3.6e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
HIMKHNBD_03249 8.7e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HIMKHNBD_03250 2.2e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HIMKHNBD_03252 2.7e-46 yjdF S Protein of unknown function (DUF2992)
HIMKHNBD_03253 1.1e-72 yeaL S membrane
HIMKHNBD_03254 2.4e-193 ytvI S sporulation integral membrane protein YtvI
HIMKHNBD_03255 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HIMKHNBD_03256 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HIMKHNBD_03257 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HIMKHNBD_03258 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HIMKHNBD_03259 1.1e-75 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HIMKHNBD_03260 4.7e-76 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HIMKHNBD_03261 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
HIMKHNBD_03262 0.0 dnaE 2.7.7.7 L DNA polymerase
HIMKHNBD_03263 6.5e-224 dnaE 2.7.7.7 L DNA polymerase
HIMKHNBD_03264 9.2e-56 ytrH S Sporulation protein YtrH
HIMKHNBD_03265 4.3e-86 ytrI
HIMKHNBD_03266 5.8e-23
HIMKHNBD_03267 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HIMKHNBD_03268 1.5e-46 ytpI S YtpI-like protein
HIMKHNBD_03269 1.6e-236 ytoI K transcriptional regulator containing CBS domains
HIMKHNBD_03270 1.3e-128 ytkL S Belongs to the UPF0173 family
HIMKHNBD_03271 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMKHNBD_03273 1.3e-237 argH 4.3.2.1 E argininosuccinate lyase
HIMKHNBD_03274 6.9e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HIMKHNBD_03275 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HIMKHNBD_03276 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIMKHNBD_03277 9.1e-181 ytxK 2.1.1.72 L DNA methylase
HIMKHNBD_03278 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIMKHNBD_03279 1.6e-60 ytfJ S Sporulation protein YtfJ
HIMKHNBD_03280 1e-93 ytfI S Protein of unknown function (DUF2953)
HIMKHNBD_03281 1e-87 yteJ S RDD family
HIMKHNBD_03282 4.2e-181 sppA OU signal peptide peptidase SppA
HIMKHNBD_03283 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIMKHNBD_03284 0.0 ytcJ S amidohydrolase
HIMKHNBD_03285 4.2e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HIMKHNBD_03286 3.9e-31 sspB S spore protein
HIMKHNBD_03287 5.6e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIMKHNBD_03288 3.5e-208 iscS2 2.8.1.7 E Cysteine desulfurase
HIMKHNBD_03289 2.6e-239 braB E Component of the transport system for branched-chain amino acids
HIMKHNBD_03290 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HIMKHNBD_03291 2.1e-151 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HIMKHNBD_03292 1.7e-108 yttP K Transcriptional regulator
HIMKHNBD_03293 4.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
HIMKHNBD_03294 2.8e-281 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HIMKHNBD_03295 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIMKHNBD_03296 3.6e-252 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HIMKHNBD_03298 1.3e-07
HIMKHNBD_03301 2e-08
HIMKHNBD_03306 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMKHNBD_03307 2.1e-219 glcP G Major Facilitator Superfamily
HIMKHNBD_03308 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIMKHNBD_03309 1.4e-175 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HIMKHNBD_03310 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HIMKHNBD_03311 6.7e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HIMKHNBD_03312 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
HIMKHNBD_03313 6e-108 ybbA S Putative esterase
HIMKHNBD_03314 6.1e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMKHNBD_03315 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMKHNBD_03316 2e-172 feuA P Iron-uptake system-binding protein
HIMKHNBD_03317 3.3e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HIMKHNBD_03318 8.6e-237 ybbC 3.2.1.52 S protein conserved in bacteria
HIMKHNBD_03319 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HIMKHNBD_03320 5.8e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HIMKHNBD_03321 1.6e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMKHNBD_03322 9.2e-159 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HIMKHNBD_03323 7.7e-85 ybbJ J acetyltransferase
HIMKHNBD_03324 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HIMKHNBD_03330 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HIMKHNBD_03331 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HIMKHNBD_03332 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIMKHNBD_03333 1.3e-223 ybbR S protein conserved in bacteria
HIMKHNBD_03334 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIMKHNBD_03335 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIMKHNBD_03336 3.2e-153 V ATPases associated with a variety of cellular activities
HIMKHNBD_03337 1.4e-105 S ABC-2 family transporter protein
HIMKHNBD_03338 3.6e-99 ybdN
HIMKHNBD_03339 2.4e-132 ybdO S Domain of unknown function (DUF4885)
HIMKHNBD_03340 2.1e-162 dkgB S Aldo/keto reductase family
HIMKHNBD_03341 2.9e-93 yxaC M effector of murein hydrolase
HIMKHNBD_03342 6.9e-52 S LrgA family
HIMKHNBD_03343 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
HIMKHNBD_03344 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HIMKHNBD_03345 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
HIMKHNBD_03346 1.2e-205 yetM CH FAD binding domain
HIMKHNBD_03347 1.8e-30 yetN S Protein of unknown function (DUF3900)
HIMKHNBD_03348 3.6e-133 yetN S Protein of unknown function (DUF3900)
HIMKHNBD_03349 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HIMKHNBD_03350 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HIMKHNBD_03351 1.8e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
HIMKHNBD_03352 7.1e-172 yfnG 4.2.1.45 M dehydratase
HIMKHNBD_03353 1e-178 yfnF M Nucleotide-diphospho-sugar transferase
HIMKHNBD_03354 2.8e-221 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HIMKHNBD_03355 6.9e-186 yfnD M Nucleotide-diphospho-sugar transferase
HIMKHNBD_03356 7.2e-139 fsr P COG0477 Permeases of the major facilitator superfamily
HIMKHNBD_03357 4.5e-59 fsr P COG0477 Permeases of the major facilitator superfamily
HIMKHNBD_03358 3e-246 yfnA E amino acid
HIMKHNBD_03359 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIMKHNBD_03360 7.5e-107 yfmS NT chemotaxis protein
HIMKHNBD_03361 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
HIMKHNBD_03362 6.1e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMKHNBD_03363 2.5e-46 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HIMKHNBD_03364 5.6e-281 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HIMKHNBD_03365 1.8e-69 yfmP K transcriptional
HIMKHNBD_03366 7.5e-206 yfmO EGP Major facilitator Superfamily
HIMKHNBD_03367 3.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HIMKHNBD_03368 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HIMKHNBD_03369 2.8e-44 yfmK 2.3.1.128 K acetyltransferase
HIMKHNBD_03370 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
HIMKHNBD_03371 4.5e-24 S Protein of unknown function (DUF3212)
HIMKHNBD_03372 1.3e-57 yflT S Heat induced stress protein YflT
HIMKHNBD_03373 1.7e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HIMKHNBD_03374 3.9e-233 yflS P Sodium:sulfate symporter transmembrane region
HIMKHNBD_03375 2.3e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HIMKHNBD_03376 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HIMKHNBD_03377 2.4e-33 yaaA S S4 domain
HIMKHNBD_03378 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HIMKHNBD_03379 8.1e-38 yaaB S Domain of unknown function (DUF370)
HIMKHNBD_03380 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIMKHNBD_03381 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIMKHNBD_03382 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMKHNBD_03385 9.7e-183 yaaC S YaaC-like Protein
HIMKHNBD_03386 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HIMKHNBD_03387 1.1e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HIMKHNBD_03388 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HIMKHNBD_03389 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HIMKHNBD_03390 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIMKHNBD_03391 1.3e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HIMKHNBD_03392 1.3e-09
HIMKHNBD_03393 1.6e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HIMKHNBD_03394 1e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HIMKHNBD_03395 3.8e-211 yaaH M Glycoside Hydrolase Family
HIMKHNBD_03396 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
HIMKHNBD_03397 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIMKHNBD_03398 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIMKHNBD_03399 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HIMKHNBD_03400 1.1e-09 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIMKHNBD_03401 3.7e-90 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIMKHNBD_03402 3.6e-32 yaaL S Protein of unknown function (DUF2508)
HIMKHNBD_03403 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
HIMKHNBD_03404 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMKHNBD_03407 2.2e-26 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HIMKHNBD_03408 1.5e-103 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HIMKHNBD_03409 9.2e-32
HIMKHNBD_03410 1e-81 K Helix-turn-helix XRE-family like proteins
HIMKHNBD_03411 2e-194 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
HIMKHNBD_03412 1.2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HIMKHNBD_03413 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIMKHNBD_03414 1.9e-86 ybfM S SNARE associated Golgi protein
HIMKHNBD_03415 4.7e-151 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HIMKHNBD_03416 6.1e-42 ybfN
HIMKHNBD_03417 5.6e-191 yceA S Belongs to the UPF0176 family
HIMKHNBD_03418 1.6e-214 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIMKHNBD_03419 9.5e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HIMKHNBD_03420 1.5e-256 mmuP E amino acid
HIMKHNBD_03421 1.8e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HIMKHNBD_03422 1.7e-257 agcS E Sodium alanine symporter
HIMKHNBD_03423 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
HIMKHNBD_03424 3.7e-206 phoQ 2.7.13.3 T Histidine kinase
HIMKHNBD_03425 2.2e-171 glnL T Regulator
HIMKHNBD_03426 1.3e-125 ycbJ S Macrolide 2'-phosphotransferase
HIMKHNBD_03427 1.2e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HIMKHNBD_03428 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIMKHNBD_03429 1.7e-108 ydfN C nitroreductase
HIMKHNBD_03430 3.2e-183 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HIMKHNBD_03431 1.5e-62 mhqP S DoxX
HIMKHNBD_03432 3.5e-55 traF CO Thioredoxin
HIMKHNBD_03434 2e-51 yhiD S MgtC SapB transporter
HIMKHNBD_03435 9.3e-27 yhiD S MgtC SapB transporter
HIMKHNBD_03436 2.9e-21 yjfB S Putative motility protein
HIMKHNBD_03437 2.3e-66 T PhoQ Sensor
HIMKHNBD_03438 5.9e-100 yjgB S Domain of unknown function (DUF4309)
HIMKHNBD_03439 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HIMKHNBD_03440 1.2e-205 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
HIMKHNBD_03441 4.3e-92 yjgD S Protein of unknown function (DUF1641)
HIMKHNBD_03442 4.8e-224 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HIMKHNBD_03443 1.2e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HIMKHNBD_03444 6.8e-29
HIMKHNBD_03445 5.1e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HIMKHNBD_03446 2.1e-124 ybbM S transport system, permease component
HIMKHNBD_03447 7.1e-130 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
HIMKHNBD_03448 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
HIMKHNBD_03449 1.2e-88 yjlB S Cupin domain
HIMKHNBD_03450 7e-66 yjlC S Protein of unknown function (DUF1641)
HIMKHNBD_03451 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
HIMKHNBD_03452 1.9e-272 uxaC 5.3.1.12 G glucuronate isomerase
HIMKHNBD_03453 3.3e-253 yjmB G symporter YjmB
HIMKHNBD_03454 7e-181 exuR K transcriptional
HIMKHNBD_03455 4e-278 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HIMKHNBD_03456 1.1e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HIMKHNBD_03457 4e-87 T Transcriptional regulatory protein, C terminal
HIMKHNBD_03458 1.4e-131 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HIMKHNBD_03459 3.2e-19 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HIMKHNBD_03460 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HIMKHNBD_03461 3.3e-161 yyaK S CAAX protease self-immunity
HIMKHNBD_03462 2e-247 ydjK G Sugar (and other) transporter
HIMKHNBD_03463 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMKHNBD_03464 5.2e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HIMKHNBD_03465 1.6e-140 xth 3.1.11.2 L exodeoxyribonuclease III
HIMKHNBD_03466 1e-96 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIMKHNBD_03467 4.1e-104 adaA 3.2.2.21 K Transcriptional regulator
HIMKHNBD_03468 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HIMKHNBD_03469 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HIMKHNBD_03470 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HIMKHNBD_03471 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIMKHNBD_03472 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIMKHNBD_03473 2.3e-33 yyzM S protein conserved in bacteria
HIMKHNBD_03474 1.5e-175 yyaD S Membrane
HIMKHNBD_03475 1.2e-46 4.2.1.103 K FR47-like protein
HIMKHNBD_03476 6.2e-111 yyaC S Sporulation protein YyaC
HIMKHNBD_03477 7.9e-149 spo0J K Belongs to the ParB family
HIMKHNBD_03478 9.2e-136 soj D COG1192 ATPases involved in chromosome partitioning
HIMKHNBD_03479 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HIMKHNBD_03480 1.6e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HIMKHNBD_03481 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HIMKHNBD_03482 1.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HIMKHNBD_03483 1.3e-108 jag S single-stranded nucleic acid binding R3H
HIMKHNBD_03484 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIMKHNBD_03485 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HIMKHNBD_03486 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HIMKHNBD_03487 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HIMKHNBD_03489 7.1e-18 tlp S Belongs to the Tlp family
HIMKHNBD_03490 8.3e-75 yneP S Thioesterase-like superfamily
HIMKHNBD_03491 1.4e-52 yneQ
HIMKHNBD_03492 1.1e-49 yneR S Belongs to the HesB IscA family
HIMKHNBD_03493 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIMKHNBD_03494 1.5e-68 yccU S CoA-binding protein
HIMKHNBD_03495 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIMKHNBD_03496 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIMKHNBD_03497 6e-13
HIMKHNBD_03498 5.1e-41 ynfC
HIMKHNBD_03499 5.2e-246 agcS E Sodium alanine symporter
HIMKHNBD_03500 2.6e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HIMKHNBD_03501 1.7e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HIMKHNBD_03502 5.8e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HIMKHNBD_03503 1.1e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HIMKHNBD_03504 2.2e-143 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMKHNBD_03505 2.1e-11 kdgR_1 K transcriptional
HIMKHNBD_03506 4.4e-141 kdgR_1 K transcriptional
HIMKHNBD_03507 7.9e-40 exuT G Sugar (and other) transporter
HIMKHNBD_03508 2.1e-154 yndG S DoxX-like family
HIMKHNBD_03509 9.5e-80 yndH S Domain of unknown function (DUF4166)
HIMKHNBD_03510 1.2e-294 yndJ S YndJ-like protein
HIMKHNBD_03512 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HIMKHNBD_03513 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HIMKHNBD_03514 1.6e-142 est 3.1.1.1 S Carboxylesterase
HIMKHNBD_03515 4.8e-24 secG U Preprotein translocase subunit SecG
HIMKHNBD_03516 6e-35 yvzC K Transcriptional
HIMKHNBD_03517 1e-69 K transcriptional
HIMKHNBD_03518 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
HIMKHNBD_03519 8.8e-53 yodB K transcriptional
HIMKHNBD_03520 2.4e-259 T His Kinase A (phosphoacceptor) domain
HIMKHNBD_03521 1.4e-121 K Transcriptional regulatory protein, C terminal
HIMKHNBD_03522 4.7e-132 mutG S ABC-2 family transporter protein
HIMKHNBD_03523 6e-121 spaE S ABC-2 family transporter protein
HIMKHNBD_03524 1.2e-126 mutF V ABC transporter, ATP-binding protein
HIMKHNBD_03525 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HIMKHNBD_03526 3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HIMKHNBD_03527 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HIMKHNBD_03528 3.4e-59 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HIMKHNBD_03529 1.2e-132 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HIMKHNBD_03530 4.3e-76 yvbF K Belongs to the GbsR family
HIMKHNBD_03531 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HIMKHNBD_03532 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HIMKHNBD_03533 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HIMKHNBD_03534 3.3e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HIMKHNBD_03535 3.5e-97 yvbF K Belongs to the GbsR family
HIMKHNBD_03536 9.8e-104 yvbG U UPF0056 membrane protein
HIMKHNBD_03537 3.8e-120 exoY M Membrane
HIMKHNBD_03538 0.0 tcaA S response to antibiotic
HIMKHNBD_03539 2.5e-80 yvbK 3.1.3.25 K acetyltransferase
HIMKHNBD_03540 1.3e-140 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_03541 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_03542 1.5e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HIMKHNBD_03543 3.5e-185 yoxA 5.1.3.3 G Aldose 1-epimerase
HIMKHNBD_03544 6.7e-246 yoeA V MATE efflux family protein
HIMKHNBD_03545 3.6e-94 yoeB S IseA DL-endopeptidase inhibitor
HIMKHNBD_03546 1.1e-271 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_03547 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_03548 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMKHNBD_03550 1.4e-144 yiiD K acetyltransferase
HIMKHNBD_03551 1.2e-241 cgeD M maturation of the outermost layer of the spore
HIMKHNBD_03552 8.1e-40 cgeC
HIMKHNBD_03553 1.6e-52 cgeA
HIMKHNBD_03554 1.4e-178 cgeB S Spore maturation protein
HIMKHNBD_03555 5.8e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HIMKHNBD_03556 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
HIMKHNBD_03562 1.7e-77
HIMKHNBD_03563 2.5e-22 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HIMKHNBD_03564 2.6e-08
HIMKHNBD_03567 1.1e-75 yoqH M LysM domain
HIMKHNBD_03568 5e-207 S aspartate phosphatase
HIMKHNBD_03571 2.8e-113 3.4.24.40 S amine dehydrogenase activity
HIMKHNBD_03572 2.8e-21 3.4.24.40 S amine dehydrogenase activity
HIMKHNBD_03574 2e-08 S Domain of unknown function (DUF4879)
HIMKHNBD_03575 4e-23
HIMKHNBD_03576 6.6e-30 S Acetyltransferase (GNAT) domain
HIMKHNBD_03577 1.5e-87 yokK S SMI1 / KNR4 family
HIMKHNBD_03578 7.5e-53 S SMI1-KNR4 cell-wall
HIMKHNBD_03579 2.8e-289 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HIMKHNBD_03580 5.6e-115 ynaE S Domain of unknown function (DUF3885)
HIMKHNBD_03581 3.9e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMKHNBD_03582 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
HIMKHNBD_03584 3.3e-92 yvgO
HIMKHNBD_03586 0.0 yobO M Pectate lyase superfamily protein
HIMKHNBD_03587 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HIMKHNBD_03588 9.4e-139 yndL S Replication protein
HIMKHNBD_03589 9.1e-08
HIMKHNBD_03590 2.2e-129 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
HIMKHNBD_03591 1.2e-71 yndM S Protein of unknown function (DUF2512)
HIMKHNBD_03592 2.1e-12 yoaW
HIMKHNBD_03593 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIMKHNBD_03594 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HIMKHNBD_03595 3.5e-112 yneB L resolvase
HIMKHNBD_03596 9.8e-33 ynzC S UPF0291 protein
HIMKHNBD_03597 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HIMKHNBD_03598 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
HIMKHNBD_03599 2.3e-28 yneF S UPF0154 protein
HIMKHNBD_03600 6e-15 ynzD S Spo0E like sporulation regulatory protein
HIMKHNBD_03601 1.3e-125 ccdA O cytochrome c biogenesis protein
HIMKHNBD_03602 3e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HIMKHNBD_03603 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HIMKHNBD_03604 2.5e-74 yneK S Protein of unknown function (DUF2621)
HIMKHNBD_03605 1.4e-62 hspX O Spore coat protein
HIMKHNBD_03606 1.6e-129 MA20_18170 S membrane transporter protein
HIMKHNBD_03607 3.1e-78 yjoA S DinB family
HIMKHNBD_03608 2.5e-214 S response regulator aspartate phosphatase
HIMKHNBD_03610 1.9e-167 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HIMKHNBD_03611 8e-61 yjqA S Bacterial PH domain
HIMKHNBD_03612 1.4e-110 yjqB S phage-related replication protein
HIMKHNBD_03614 1.6e-58 xkdA E IrrE N-terminal-like domain
HIMKHNBD_03615 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
HIMKHNBD_03617 1.5e-149 xkdC L Bacterial dnaA protein
HIMKHNBD_03620 2e-10 yqaO S Phage-like element PBSX protein XtrA
HIMKHNBD_03621 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HIMKHNBD_03622 3e-110 xtmA L phage terminase small subunit
HIMKHNBD_03623 7.2e-210 xtmB S phage terminase, large subunit
HIMKHNBD_03624 2.3e-241 yqbA S portal protein
HIMKHNBD_03625 1.7e-90 xkdF 2.1.1.72 L Putative phage serine protease XkdF
HIMKHNBD_03626 4.6e-158 xkdG S Phage capsid family
HIMKHNBD_03627 4.3e-46 yqbG S Protein of unknown function (DUF3199)
HIMKHNBD_03628 2.7e-42 yqbH S Domain of unknown function (DUF3599)
HIMKHNBD_03629 5.3e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
HIMKHNBD_03630 3.2e-56 xkdJ
HIMKHNBD_03631 8.2e-15
HIMKHNBD_03632 1.3e-225 xkdK S Phage tail sheath C-terminal domain
HIMKHNBD_03633 2e-74 xkdM S Phage tail tube protein
HIMKHNBD_03634 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
HIMKHNBD_03635 3.4e-19
HIMKHNBD_03636 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
HIMKHNBD_03637 1.7e-227 NU Prophage endopeptidase tail
HIMKHNBD_03638 1.6e-109 S Phage tail protein
HIMKHNBD_03639 0.0 S peptidoglycan catabolic process
HIMKHNBD_03640 4.2e-116 S peptidoglycan catabolic process
HIMKHNBD_03641 1.9e-11
HIMKHNBD_03642 9.2e-24
HIMKHNBD_03643 4.4e-61
HIMKHNBD_03644 4.3e-30
HIMKHNBD_03645 2.3e-47 S Bacteriophage HK97-gp10, putative tail-component
HIMKHNBD_03646 1.4e-14 S Phage head-tail joining protein
HIMKHNBD_03647 1.5e-24 S Phage gp6-like head-tail connector protein
HIMKHNBD_03648 5.8e-44 S peptidoglycan catabolic process
HIMKHNBD_03650 4.2e-180 S capsid protein
HIMKHNBD_03651 4.5e-109 S peptidase activity
HIMKHNBD_03652 1.4e-239 S Phage portal protein
HIMKHNBD_03653 1e-10
HIMKHNBD_03654 3.7e-230 S Phage Terminase
HIMKHNBD_03655 8.7e-87 S Phage terminase, small subunit
HIMKHNBD_03656 7.3e-55 S HNH endonuclease
HIMKHNBD_03657 9.1e-92 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HIMKHNBD_03658 2.8e-142 S PQQ-like domain
HIMKHNBD_03659 1.7e-64 S Family of unknown function (DUF5391)
HIMKHNBD_03660 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
HIMKHNBD_03661 1.8e-168 EGP Major facilitator Superfamily
HIMKHNBD_03662 3.8e-73 yxaI S membrane protein domain
HIMKHNBD_03663 4.9e-125 E Ring-cleavage extradiol dioxygenase
HIMKHNBD_03664 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HIMKHNBD_03665 1.1e-286 ahpF O Alkyl hydroperoxide reductase
HIMKHNBD_03666 4.8e-213 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
HIMKHNBD_03667 2e-21 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
HIMKHNBD_03668 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HIMKHNBD_03669 5.9e-82 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HIMKHNBD_03670 2.6e-152 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HIMKHNBD_03671 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HIMKHNBD_03672 1.3e-87 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HIMKHNBD_03673 5.3e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HIMKHNBD_03674 8.2e-177 S Fusaric acid resistance protein-like
HIMKHNBD_03677 8.5e-58 E Glyoxalase-like domain
HIMKHNBD_03678 5.7e-161 bla 3.5.2.6 V beta-lactamase
HIMKHNBD_03679 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
HIMKHNBD_03680 1.3e-249 yfjF EGP Belongs to the major facilitator superfamily
HIMKHNBD_03681 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
HIMKHNBD_03682 1.3e-47 ganA 3.2.1.89 G arabinogalactan
HIMKHNBD_03683 4.8e-151 ganA 3.2.1.89 G arabinogalactan
HIMKHNBD_03684 5.4e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HIMKHNBD_03685 1.5e-186 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HIMKHNBD_03686 1e-215 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HIMKHNBD_03687 1.7e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMKHNBD_03688 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
HIMKHNBD_03689 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
HIMKHNBD_03690 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
HIMKHNBD_03691 1.7e-122 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HIMKHNBD_03693 3.9e-10
HIMKHNBD_03698 2.3e-28
HIMKHNBD_03699 6.3e-54
HIMKHNBD_03700 5.9e-69
HIMKHNBD_03701 1.7e-107 virB11 2.1.1.37 NU Type II/IV secretion system protein
HIMKHNBD_03702 1.5e-20
HIMKHNBD_03705 1.9e-213 M domain protein
HIMKHNBD_03707 4.1e-25 S Domain of unknown function (DUF5052)
HIMKHNBD_03708 2.2e-07 ddpX 3.4.13.22 F protein conserved in bacteria
HIMKHNBD_03710 8.8e-07 K transcriptional
HIMKHNBD_03712 2.2e-38 S Domain of unknown function (DUF771)
HIMKHNBD_03714 7.8e-22 K Helix-turn-helix XRE-family like proteins
HIMKHNBD_03717 3.3e-70
HIMKHNBD_03718 6.9e-116 L Phage integrase family
HIMKHNBD_03720 3.5e-97 L Integrase
HIMKHNBD_03721 1.8e-34 yoeD G Helix-turn-helix domain
HIMKHNBD_03722 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HIMKHNBD_03723 3.4e-198 ybcL EGP Major facilitator Superfamily
HIMKHNBD_03724 1.8e-50 ybzH K Helix-turn-helix domain
HIMKHNBD_03726 4.1e-153 gltR1 K Transcriptional regulator
HIMKHNBD_03727 6.1e-81 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HIMKHNBD_03728 2.5e-80 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HIMKHNBD_03729 2.8e-112 S CAAX protease self-immunity
HIMKHNBD_03730 8.6e-153 sagB C Nitroreductase family
HIMKHNBD_03731 1.1e-261 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
HIMKHNBD_03732 9.8e-183 S ATP diphosphatase activity
HIMKHNBD_03733 6.6e-125
HIMKHNBD_03734 1.8e-22 S protein homooligomerization
HIMKHNBD_03735 1.3e-10 S protein homooligomerization
HIMKHNBD_03737 1.3e-126 V ABC-2 type transporter
HIMKHNBD_03738 1.5e-161 V ATPases associated with a variety of cellular activities
HIMKHNBD_03739 5.3e-50 MA20_23570 K Winged helix DNA-binding domain
HIMKHNBD_03745 7.8e-08
HIMKHNBD_03753 1.6e-08
HIMKHNBD_03757 9.5e-54 C Na+/H+ antiporter family
HIMKHNBD_03758 4.4e-129 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HIMKHNBD_03759 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HIMKHNBD_03760 9e-264 ygaK C Berberine and berberine like
HIMKHNBD_03761 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
HIMKHNBD_03762 0.0 ywpD T PhoQ Sensor
HIMKHNBD_03763 1.1e-150 M1-574 T Transcriptional regulatory protein, C terminal
HIMKHNBD_03765 9.8e-59 S SMART Tetratricopeptide domain protein
HIMKHNBD_03766 2.5e-153
HIMKHNBD_03771 7.5e-64 V ABC transporter
HIMKHNBD_03772 5.4e-85 S Protein of unknown function (DUF1430)
HIMKHNBD_03774 3.5e-252 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMKHNBD_03775 2.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
HIMKHNBD_03776 2.4e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMKHNBD_03777 2.8e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HIMKHNBD_03778 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
HIMKHNBD_03779 1e-120 tcyL P Binding-protein-dependent transport system inner membrane component
HIMKHNBD_03780 2.7e-146 tcyK M Bacterial periplasmic substrate-binding proteins
HIMKHNBD_03781 3.9e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
HIMKHNBD_03782 3e-101 ytmI K Acetyltransferase (GNAT) domain
HIMKHNBD_03783 7.5e-50 ytlI K LysR substrate binding domain
HIMKHNBD_03784 9.2e-101 ytlI K LysR substrate binding domain
HIMKHNBD_03785 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMKHNBD_03786 3.1e-47 yrdF K ribonuclease inhibitor
HIMKHNBD_03787 3.6e-10 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HIMKHNBD_03788 9.3e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HIMKHNBD_03789 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HIMKHNBD_03790 2.8e-165 xerD L recombinase XerD
HIMKHNBD_03791 3.7e-37 S Protein of unknown function (DUF4227)
HIMKHNBD_03792 1.9e-80 fur P Belongs to the Fur family
HIMKHNBD_03793 1.2e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HIMKHNBD_03795 8.6e-34 yqkK
HIMKHNBD_03796 5.7e-22
HIMKHNBD_03797 3.8e-243 mleA 1.1.1.38 C malic enzyme
HIMKHNBD_03798 7.4e-237 mleN C Na H antiporter
HIMKHNBD_03799 6.1e-21 ebh 2.1.1.80, 3.1.1.61 D Protein of unknown function
HIMKHNBD_03800 2e-61 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HIMKHNBD_03802 3.7e-49
HIMKHNBD_03803 3.1e-80 4.6.1.1 T Adenylate and Guanylate cyclase catalytic domain
HIMKHNBD_03807 9.2e-26 S membrane
HIMKHNBD_03808 4.6e-30 padR K PadR family transcriptional regulator
HIMKHNBD_03815 1.2e-50 yuzC
HIMKHNBD_03816 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HIMKHNBD_03817 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIMKHNBD_03818 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
HIMKHNBD_03819 7.2e-68 yueI S Protein of unknown function (DUF1694)
HIMKHNBD_03820 2.8e-38 yueH S YueH-like protein
HIMKHNBD_03821 6.4e-34 yueG S Spore germination protein gerPA/gerPF
HIMKHNBD_03822 3.6e-186 yueF S transporter activity
HIMKHNBD_03823 1.6e-22 S Protein of unknown function (DUF2642)
HIMKHNBD_03824 8.3e-96 yueE S phosphohydrolase
HIMKHNBD_03825 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMKHNBD_03826 8.1e-13 yueC S Family of unknown function (DUF5383)
HIMKHNBD_03827 9.4e-127 yeeN K transcriptional regulatory protein
HIMKHNBD_03829 6.9e-108 aadK G Streptomycin adenylyltransferase
HIMKHNBD_03830 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
HIMKHNBD_03831 3.3e-45 cotJB S CotJB protein
HIMKHNBD_03832 4.5e-100 cotJC P Spore Coat
HIMKHNBD_03833 5e-93 yesJ K Acetyltransferase (GNAT) family
HIMKHNBD_03835 7.4e-121 yetF S membrane
HIMKHNBD_03836 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HIMKHNBD_03837 3.4e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMKHNBD_03838 3.2e-153 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIMKHNBD_03839 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
HIMKHNBD_03840 5.3e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
HIMKHNBD_03841 8.7e-21 yetJ S Belongs to the BI1 family
HIMKHNBD_03842 1.9e-63 yetJ S Belongs to the BI1 family
HIMKHNBD_03843 2.5e-75 S Domain of unknown function (DUF4879)
HIMKHNBD_03844 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
HIMKHNBD_03845 8e-107 yqeB
HIMKHNBD_03846 9.2e-40 ybyB
HIMKHNBD_03847 7.2e-292 ybeC E amino acid
HIMKHNBD_03848 3.7e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIMKHNBD_03849 1.7e-259 glpT G -transporter
HIMKHNBD_03850 1.3e-16 S Protein of unknown function (DUF2651)
HIMKHNBD_03851 2.3e-114 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HIMKHNBD_03852 4.9e-119 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HIMKHNBD_03853 4.4e-32 nrdI 1.17.4.1 F Belongs to the NrdI family
HIMKHNBD_03854 3.7e-294 recD 3.1.11.5 L Helix-hairpin-helix containing domain
HIMKHNBD_03856 8.8e-38 S Macro domain
HIMKHNBD_03863 5.1e-17 S Helix-turn-helix domain
HIMKHNBD_03866 4.8e-10
HIMKHNBD_03876 1.4e-45 L COG2963 Transposase and inactivated derivatives
HIMKHNBD_03877 8.4e-100 L Integrase core domain
HIMKHNBD_03878 8.3e-13 pinR3 L Resolvase, N terminal domain
HIMKHNBD_03879 3.5e-22 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HIMKHNBD_03880 2.2e-47 hsdS 3.1.21.3 V COG0732 Restriction endonuclease S subunits
HIMKHNBD_03881 1.5e-248 hsdM 2.1.1.72 L type I restriction-modification system
HIMKHNBD_03882 3.1e-193 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HIMKHNBD_03883 9e-128 S PD-(D/E)XK nuclease superfamily
HIMKHNBD_03884 3.2e-70 tdk 2.7.1.21 F thymidine kinase
HIMKHNBD_03885 1.5e-43 S DNA primase activity
HIMKHNBD_03887 2.9e-43 S Predicted nucleotidyltransferase
HIMKHNBD_03891 2.4e-15 yxcD S Protein of unknown function (DUF2653)
HIMKHNBD_03893 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIMKHNBD_03895 1.9e-297 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HIMKHNBD_03896 2.5e-83 ywrC K Transcriptional regulator
HIMKHNBD_03897 5e-102 ywrB P Chromate transporter
HIMKHNBD_03898 8.4e-29 ywrA P COG2059 Chromate transport protein ChrA
HIMKHNBD_03899 2.5e-40 ywrA P COG2059 Chromate transport protein ChrA
HIMKHNBD_03901 8.8e-93 ywqN S NAD(P)H-dependent
HIMKHNBD_03902 3.1e-156 K Transcriptional regulator
HIMKHNBD_03905 5.7e-173 U TraM recognition site of TraD and TraG
HIMKHNBD_03908 2.5e-171 trsE S AAA-like domain
HIMKHNBD_03910 1.6e-53 M Lysozyme-like
HIMKHNBD_03911 1.3e-07
HIMKHNBD_03915 1.3e-08 virB5 U conjugation
HIMKHNBD_03916 4.6e-95
HIMKHNBD_03920 4.9e-27 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HIMKHNBD_03921 7.9e-197 T COG4585 Signal transduction histidine kinase
HIMKHNBD_03922 1.2e-109 KT LuxR family transcriptional regulator
HIMKHNBD_03923 3e-165 V COG1131 ABC-type multidrug transport system, ATPase component
HIMKHNBD_03924 4.6e-203 V COG0842 ABC-type multidrug transport system, permease component
HIMKHNBD_03925 6.3e-124 V ABC-2 family transporter protein
HIMKHNBD_03927 3.2e-09 T Histidine kinase
HIMKHNBD_03928 4e-41 S Protein of unknown function (DUF2568)
HIMKHNBD_03930 3.2e-11
HIMKHNBD_03932 9.2e-94
HIMKHNBD_03933 8.6e-24
HIMKHNBD_03934 0.0 dnaE_2 2.7.7.7 L DNA polymerase
HIMKHNBD_03937 9.2e-111 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIMKHNBD_03938 5.4e-77
HIMKHNBD_03939 7.2e-274 gp17a S Terminase-like family
HIMKHNBD_03940 9e-55
HIMKHNBD_03941 3.8e-67
HIMKHNBD_03943 2.3e-13 S Domain of unknown function (DUF2479)
HIMKHNBD_03944 2.8e-256 fliC N bacterial-type flagellum-dependent cell motility
HIMKHNBD_03945 7.7e-111
HIMKHNBD_03949 1.6e-21 S Domain of unknown function (DUF4062)
HIMKHNBD_03952 2.1e-41 L Site-specific recombinase, phage integrase family
HIMKHNBD_03954 3e-13 S Repressor of ComK
HIMKHNBD_03957 4.4e-143 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L DNA ligase OB-like domain
HIMKHNBD_03959 1.5e-28 S PFAM 3D domain-containing protein
HIMKHNBD_03960 2.2e-70 2.7.1.24 H dephospho-CoA kinase activity
HIMKHNBD_03963 1.8e-71 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMKHNBD_03966 1.4e-29 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HIMKHNBD_03967 1.5e-72 S Protein of unknown function (DUF3800)
HIMKHNBD_03968 4.5e-19 K Helix-turn-helix domain
HIMKHNBD_03971 1.4e-22
HIMKHNBD_03972 1e-41 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HIMKHNBD_03973 2.5e-66 S COG0790 FOG TPR repeat, SEL1 subfamily
HIMKHNBD_03975 1.1e-75 L Protein of unknown function (DUF3991)
HIMKHNBD_03978 2.8e-15
HIMKHNBD_03979 4e-124 wapA M COG3209 Rhs family protein
HIMKHNBD_03980 3.3e-175 wapA M COG3209 Rhs family protein
HIMKHNBD_03981 1.7e-227 NU Prophage endopeptidase tail
HIMKHNBD_03982 5.5e-102 S Phage tail protein
HIMKHNBD_03983 1.3e-76 D phage tail tape measure protein
HIMKHNBD_03985 5.8e-196 3.6.3.27 V Peptidase C39 family
HIMKHNBD_03988 6.1e-09 K sequence-specific DNA binding
HIMKHNBD_03989 4.5e-22
HIMKHNBD_03991 1.6e-45
HIMKHNBD_03997 1.2e-70 U Protein of unknown function DUF262
HIMKHNBD_03998 1.9e-164 virD3 2.1.1.37 NU DNA (cytosine-5-)-methyltransferase activity
HIMKHNBD_03999 5.8e-18 nucH 3.1.31.1 L Staphylococcal nuclease homologues
HIMKHNBD_04001 8e-18
HIMKHNBD_04002 3.8e-116 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
HIMKHNBD_04003 7.8e-13 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L DNA ligase OB-like domain
HIMKHNBD_04006 3.4e-48 ubiE2 Q Methyltransferase domain
HIMKHNBD_04008 2.1e-12
HIMKHNBD_04010 8.5e-162 S response regulator aspartate phosphatase
HIMKHNBD_04012 0.0 L HKD family nuclease
HIMKHNBD_04013 1.7e-111 wapA M COG3209 Rhs family protein
HIMKHNBD_04014 1.2e-15 wapA M COG3209 Rhs family protein
HIMKHNBD_04015 7.4e-14 K Helix-turn-helix XRE-family like proteins
HIMKHNBD_04016 1.1e-09 K transcriptional regulator with C-terminal CBS domains
HIMKHNBD_04017 6.5e-32
HIMKHNBD_04018 1.2e-71 S DNA binding
HIMKHNBD_04019 5.8e-87
HIMKHNBD_04021 3.5e-07 S Hypothetical protein Yqai
HIMKHNBD_04024 1.5e-117 D phage tail tape measure protein
HIMKHNBD_04025 2.7e-110 D phage tail tape measure protein
HIMKHNBD_04026 6.3e-69
HIMKHNBD_04027 9.6e-179 S Histidine kinase
HIMKHNBD_04029 9e-33 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIMKHNBD_04030 4.5e-63 fabZ 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HIMKHNBD_04031 9.6e-195 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIMKHNBD_04032 8e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
HIMKHNBD_04033 3.6e-147 yxxF EG EamA-like transporter family
HIMKHNBD_04034 1.2e-15 yxiE T Belongs to the universal stress protein A family
HIMKHNBD_04037 6.4e-177 S Aspartate phosphatase response regulator
HIMKHNBD_04038 2.4e-11 S Aspartate phosphatase response regulator
HIMKHNBD_04039 9.3e-53
HIMKHNBD_04040 5e-67 S Phage portal protein
HIMKHNBD_04041 2.5e-83 S peptidase activity
HIMKHNBD_04042 1.5e-154 gp36 S capsid protein
HIMKHNBD_04044 1.9e-173 lcnDR2 V Lanthionine synthetase C-like protein
HIMKHNBD_04045 4.5e-67 S DinB family
HIMKHNBD_04046 5.4e-35 K WYL domain
HIMKHNBD_04047 1e-51 K WYL domain
HIMKHNBD_04048 7e-17
HIMKHNBD_04049 2.1e-250 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIMKHNBD_04050 2.3e-96 ydfC EG EamA-like transporter family
HIMKHNBD_04054 1.4e-300 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HIMKHNBD_04064 9.6e-75 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIMKHNBD_04065 1.7e-55 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIMKHNBD_04066 1.4e-11 S YolD-like protein
HIMKHNBD_04069 3.3e-32
HIMKHNBD_04071 2.5e-11 yrdF K ribonuclease inhibitor
HIMKHNBD_04072 7.1e-31 yrdF K ribonuclease inhibitor
HIMKHNBD_04073 7.9e-56
HIMKHNBD_04078 3.8e-37 xerH L Belongs to the 'phage' integrase family
HIMKHNBD_04079 2.9e-65 xerH L Belongs to the 'phage' integrase family
HIMKHNBD_04080 3.2e-21 D Phage-related minor tail protein
HIMKHNBD_04081 9e-12
HIMKHNBD_04082 8.9e-47 F nucleoside 2-deoxyribosyltransferase
HIMKHNBD_04083 3.6e-70 L Phage integrase family
HIMKHNBD_04084 1.4e-40 wecC 1.1.1.336 M ArpU family transcriptional regulator
HIMKHNBD_04085 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HIMKHNBD_04086 6.5e-138 cylB V ABC-2 type transporter
HIMKHNBD_04090 1.6e-78 3.1.3.16 L DnaD domain protein
HIMKHNBD_04092 2.6e-67 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HIMKHNBD_04093 7.1e-72 2.1.1.265 H Tellurite resistance protein TehB
HIMKHNBD_04094 2.1e-140 EGP Transmembrane secretion effector
HIMKHNBD_04095 1.3e-18 S cellulase activity
HIMKHNBD_04096 8.7e-67
HIMKHNBD_04099 3.7e-07
HIMKHNBD_04101 3.8e-50 dnaC L DNA replication protein
HIMKHNBD_04103 5.2e-23 Q PFAM Collagen triple helix
HIMKHNBD_04105 4.9e-72
HIMKHNBD_04106 2.2e-14 S Bacteriophage replication protein O
HIMKHNBD_04108 4.5e-106 D Phage-related minor tail protein
HIMKHNBD_04109 3.8e-87 traC L Domain of unknown function (DUF1738)
HIMKHNBD_04112 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMKHNBD_04115 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMKHNBD_04118 1.2e-41 yoaP 3.1.3.18 K YoaP-like
HIMKHNBD_04119 9.9e-61 yoaP 3.1.3.18 K YoaP-like
HIMKHNBD_04120 6.3e-99 J Acetyltransferase (GNAT) domain
HIMKHNBD_04121 2.6e-197 S Peptidase_G2, IMC autoproteolytic cleavage domain
HIMKHNBD_04125 2.5e-32 isp O Belongs to the peptidase S8 family
HIMKHNBD_04126 4.2e-19
HIMKHNBD_04127 4.5e-66 S Leucine-rich repeat (LRR) protein
HIMKHNBD_04128 8e-80 yobL S Bacterial EndoU nuclease
HIMKHNBD_04129 6.8e-27 S SMI1 / KNR4 family
HIMKHNBD_04133 3.6e-21 K Cro/C1-type HTH DNA-binding domain
HIMKHNBD_04135 5.6e-63 S Pfam:Phage_holin_4_1
HIMKHNBD_04138 8.4e-44 S Domain of unknown function (DUF2479)
HIMKHNBD_04139 1.2e-84 S Protein of unknown function (DUF4240)
HIMKHNBD_04140 5.5e-114 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HIMKHNBD_04141 7.5e-96 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HIMKHNBD_04145 4.5e-24 S cellulase activity
HIMKHNBD_04146 1.5e-13
HIMKHNBD_04148 2.9e-105 S Aspartate phosphatase response regulator
HIMKHNBD_04149 9.5e-31 lcnDR2 V Lanthionine synthetase C-like protein
HIMKHNBD_04150 2e-33 lcnDR2 V Lanthionine synthetase C-like protein
HIMKHNBD_04151 5e-11 lcnDR2 V Lanthionine synthetase C-like protein
HIMKHNBD_04152 1.4e-55 S Domain of unknown function (DUF2479)
HIMKHNBD_04154 1.5e-16 K Transcriptional regulator
HIMKHNBD_04158 9.4e-18
HIMKHNBD_04159 6.8e-56 S Domain of unknown function (DUF4145)
HIMKHNBD_04161 2e-63 K acetyltransferase
HIMKHNBD_04163 9.3e-55
HIMKHNBD_04165 4.4e-23
HIMKHNBD_04166 3.2e-40 D nuclear chromosome segregation
HIMKHNBD_04168 3.9e-43
HIMKHNBD_04169 1.2e-21 yyaL O Highly conserved protein containing a thioredoxin domain
HIMKHNBD_04170 7.9e-99 S Protein of unknown function (DUF554)
HIMKHNBD_04171 1.1e-53 K Bacterial transcription activator, effector binding domain
HIMKHNBD_04173 2.4e-71 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HIMKHNBD_04174 9.3e-68 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HIMKHNBD_04176 1.6e-31 S Domain of unknown function (DUF5068)
HIMKHNBD_04178 1.1e-59 ymaB S MutT family
HIMKHNBD_04181 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMKHNBD_04183 2.5e-121 comP 2.7.13.3 T Histidine kinase
HIMKHNBD_04184 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMKHNBD_04187 2.8e-15 yqaO S Phage-like element PBSX protein XtrA
HIMKHNBD_04191 8.4e-27
HIMKHNBD_04193 2.6e-75 CP Membrane
HIMKHNBD_04194 7.4e-49 S Bacteriophage HK97-gp10, putative tail-component
HIMKHNBD_04196 1.4e-66 S Phage tail tube protein
HIMKHNBD_04197 2.2e-77 L phage terminase small subunit
HIMKHNBD_04198 4.9e-15 S Terminase
HIMKHNBD_04200 2.1e-17 L Transposase, Mutator family
HIMKHNBD_04201 5.1e-27 L Transposase, Mutator family
HIMKHNBD_04202 1.3e-26 bacT Q Thioesterase domain
HIMKHNBD_04203 8.8e-23 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMKHNBD_04204 4.5e-22
HIMKHNBD_04205 5.2e-23 Q PFAM Collagen triple helix
HIMKHNBD_04206 9.8e-39 Q Collagen triple helix repeat (20 copies)
HIMKHNBD_04208 3.4e-21 yqaO S Phage-like element PBSX protein XtrA
HIMKHNBD_04210 4.2e-58 rusA L Endodeoxyribonuclease RusA
HIMKHNBD_04211 3.7e-33 yobL L Belongs to the WXG100 family
HIMKHNBD_04212 2.3e-117 yobL L Belongs to the WXG100 family
HIMKHNBD_04213 8.6e-51 yobL S Bacterial EndoU nuclease
HIMKHNBD_04222 9.2e-23
HIMKHNBD_04223 9.8e-107 V ABC-2 family transporter protein
HIMKHNBD_04224 1.5e-33 V ABC-2 family transporter protein
HIMKHNBD_04228 1.7e-63 L Belongs to the 'phage' integrase family
HIMKHNBD_04231 2.9e-33
HIMKHNBD_04234 2.4e-33
HIMKHNBD_04235 3e-56 S PcfJ-like protein
HIMKHNBD_04236 5.6e-20 S Phage portal protein
HIMKHNBD_04237 2.6e-150 S Terminase
HIMKHNBD_04239 2.7e-169 3.6.4.12 L DnaB-like helicase C terminal domain
HIMKHNBD_04240 2.1e-35 nrnB S phosphohydrolase (DHH superfamily)
HIMKHNBD_04242 7.1e-84 G SMI1-KNR4 cell-wall
HIMKHNBD_04243 8.3e-08 yvzC K Transcriptional
HIMKHNBD_04245 7.8e-10 CO cell redox homeostasis
HIMKHNBD_04246 4.1e-51 Q calcium- and calmodulin-responsive adenylate cyclase activity
HIMKHNBD_04248 8.4e-177 exuT G Sugar (and other) transporter
HIMKHNBD_04250 2.4e-43 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HIMKHNBD_04251 9e-83 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIMKHNBD_04252 3.5e-29 N Kelch motif
HIMKHNBD_04256 2.4e-36
HIMKHNBD_04259 2.1e-100 S Platelet-activating factor acetylhydrolase, isoform II

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)