ORF_ID e_value Gene_name EC_number CAZy COGs Description
KLOEOPPO_00001 3.4e-39 S COG NOG14552 non supervised orthologous group
KLOEOPPO_00006 7.8e-08
KLOEOPPO_00014 2e-08
KLOEOPPO_00018 2.7e-143 spo0M S COG4326 Sporulation control protein
KLOEOPPO_00019 1.2e-26
KLOEOPPO_00020 7.6e-86 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KLOEOPPO_00021 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KLOEOPPO_00022 1.1e-261 ygaK C Berberine and berberine like
KLOEOPPO_00024 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KLOEOPPO_00025 5.3e-136 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KLOEOPPO_00026 6.2e-169 ssuA M Sulfonate ABC transporter
KLOEOPPO_00027 2.1e-146 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KLOEOPPO_00028 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KLOEOPPO_00030 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLOEOPPO_00031 4.1e-78 ygaO
KLOEOPPO_00032 4.4e-29 K Transcriptional regulator
KLOEOPPO_00034 7.9e-114 yhzB S B3/4 domain
KLOEOPPO_00035 6e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KLOEOPPO_00036 4.4e-177 yhbB S Putative amidase domain
KLOEOPPO_00037 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KLOEOPPO_00038 1.3e-108 yhbD K Protein of unknown function (DUF4004)
KLOEOPPO_00039 5.9e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KLOEOPPO_00040 2.1e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KLOEOPPO_00041 0.0 prkA T Ser protein kinase
KLOEOPPO_00042 2.5e-225 yhbH S Belongs to the UPF0229 family
KLOEOPPO_00043 2.2e-76 yhbI K DNA-binding transcription factor activity
KLOEOPPO_00044 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
KLOEOPPO_00045 3.1e-271 yhcA EGP Major facilitator Superfamily
KLOEOPPO_00046 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
KLOEOPPO_00047 2.8e-37 yhcC
KLOEOPPO_00048 2e-55
KLOEOPPO_00049 1.9e-59 yhcF K Transcriptional regulator
KLOEOPPO_00050 4e-122 yhcG V ABC transporter, ATP-binding protein
KLOEOPPO_00051 3.8e-165 yhcH V ABC transporter, ATP-binding protein
KLOEOPPO_00052 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KLOEOPPO_00053 1e-30 cspB K Cold-shock protein
KLOEOPPO_00054 4.1e-150 metQ M Belongs to the nlpA lipoprotein family
KLOEOPPO_00055 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KLOEOPPO_00056 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KLOEOPPO_00057 3.2e-40 yhcM
KLOEOPPO_00058 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KLOEOPPO_00059 1.3e-166 yhcP
KLOEOPPO_00060 1.5e-99 yhcQ M Spore coat protein
KLOEOPPO_00061 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
KLOEOPPO_00062 2.3e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KLOEOPPO_00063 9.6e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLOEOPPO_00064 9.3e-68 yhcU S Family of unknown function (DUF5365)
KLOEOPPO_00065 9.9e-68 yhcV S COG0517 FOG CBS domain
KLOEOPPO_00066 1.3e-119 yhcW 5.4.2.6 S hydrolase
KLOEOPPO_00067 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KLOEOPPO_00068 2.7e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KLOEOPPO_00069 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KLOEOPPO_00070 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KLOEOPPO_00071 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KLOEOPPO_00072 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KLOEOPPO_00073 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KLOEOPPO_00074 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
KLOEOPPO_00075 2.9e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLOEOPPO_00076 1.2e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
KLOEOPPO_00077 1.2e-38 yhdB S YhdB-like protein
KLOEOPPO_00078 4.8e-54 yhdC S Protein of unknown function (DUF3889)
KLOEOPPO_00079 1.8e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KLOEOPPO_00080 3.5e-76 nsrR K Transcriptional regulator
KLOEOPPO_00081 8.7e-239 ygxB M Conserved TM helix
KLOEOPPO_00082 2.1e-276 ycgB S Stage V sporulation protein R
KLOEOPPO_00083 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KLOEOPPO_00084 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KLOEOPPO_00085 5.4e-161 citR K Transcriptional regulator
KLOEOPPO_00086 2.5e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
KLOEOPPO_00087 1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_00088 5.9e-250 yhdG E amino acid
KLOEOPPO_00089 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KLOEOPPO_00090 9.7e-269 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KLOEOPPO_00091 5.9e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLOEOPPO_00092 8.1e-45 yhdK S Sigma-M inhibitor protein
KLOEOPPO_00093 6.6e-201 yhdL S Sigma factor regulator N-terminal
KLOEOPPO_00094 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KLOEOPPO_00095 4.4e-191 yhdN C Aldo keto reductase
KLOEOPPO_00096 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KLOEOPPO_00097 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KLOEOPPO_00098 4.1e-74 cueR K transcriptional
KLOEOPPO_00099 1.7e-221 yhdR 2.6.1.1 E Aminotransferase
KLOEOPPO_00100 1.9e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KLOEOPPO_00101 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLOEOPPO_00102 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLOEOPPO_00103 2.8e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KLOEOPPO_00105 6.6e-204 yhdY M Mechanosensitive ion channel
KLOEOPPO_00106 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KLOEOPPO_00107 1.7e-151 yheN G deacetylase
KLOEOPPO_00108 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KLOEOPPO_00109 3.1e-232 nhaC C Na H antiporter
KLOEOPPO_00110 3.4e-84 nhaX T Belongs to the universal stress protein A family
KLOEOPPO_00111 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KLOEOPPO_00112 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KLOEOPPO_00113 6.5e-108 yheG GM NAD(P)H-binding
KLOEOPPO_00114 6.3e-28 sspB S spore protein
KLOEOPPO_00115 1.3e-36 yheE S Family of unknown function (DUF5342)
KLOEOPPO_00116 5.1e-267 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KLOEOPPO_00117 7.4e-216 yheC HJ YheC/D like ATP-grasp
KLOEOPPO_00118 5.3e-201 yheB S Belongs to the UPF0754 family
KLOEOPPO_00119 9.5e-48 yheA S Belongs to the UPF0342 family
KLOEOPPO_00120 1.5e-205 yhaZ L DNA alkylation repair enzyme
KLOEOPPO_00121 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
KLOEOPPO_00122 7.1e-294 hemZ H coproporphyrinogen III oxidase
KLOEOPPO_00123 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
KLOEOPPO_00124 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KLOEOPPO_00126 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
KLOEOPPO_00127 2.4e-26 S YhzD-like protein
KLOEOPPO_00128 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
KLOEOPPO_00129 7.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KLOEOPPO_00130 2e-225 yhaO L DNA repair exonuclease
KLOEOPPO_00131 0.0 yhaN L AAA domain
KLOEOPPO_00132 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KLOEOPPO_00133 1.6e-21 yhaL S Sporulation protein YhaL
KLOEOPPO_00134 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KLOEOPPO_00135 8.7e-90 yhaK S Putative zincin peptidase
KLOEOPPO_00136 1.3e-54 yhaI S Protein of unknown function (DUF1878)
KLOEOPPO_00137 1e-113 hpr K Negative regulator of protease production and sporulation
KLOEOPPO_00138 7e-39 yhaH S YtxH-like protein
KLOEOPPO_00139 5.4e-21
KLOEOPPO_00140 3.6e-80 trpP S Tryptophan transporter TrpP
KLOEOPPO_00141 2.9e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KLOEOPPO_00142 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KLOEOPPO_00143 4.6e-137 ecsA V transporter (ATP-binding protein)
KLOEOPPO_00144 5.4e-215 ecsB U ABC transporter
KLOEOPPO_00145 5.3e-114 ecsC S EcsC protein family
KLOEOPPO_00146 4.9e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KLOEOPPO_00147 7.4e-245 yhfA C membrane
KLOEOPPO_00148 2.7e-33 1.15.1.2 C Rubrerythrin
KLOEOPPO_00149 2.2e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KLOEOPPO_00150 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KLOEOPPO_00151 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KLOEOPPO_00152 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KLOEOPPO_00153 1.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KLOEOPPO_00154 1.4e-101 yhgD K Transcriptional regulator
KLOEOPPO_00155 1e-238 yhgE S YhgE Pip N-terminal domain protein
KLOEOPPO_00156 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLOEOPPO_00157 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
KLOEOPPO_00158 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KLOEOPPO_00159 3.7e-72 3.4.13.21 S ASCH
KLOEOPPO_00160 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KLOEOPPO_00161 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KLOEOPPO_00162 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
KLOEOPPO_00163 5.5e-110 yhfK GM NmrA-like family
KLOEOPPO_00164 1e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KLOEOPPO_00165 1.9e-65 yhfM
KLOEOPPO_00166 5e-240 yhfN 3.4.24.84 O Peptidase M48
KLOEOPPO_00167 1.4e-196 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KLOEOPPO_00168 7.3e-77 VY92_01935 K acetyltransferase
KLOEOPPO_00169 7e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
KLOEOPPO_00170 4.8e-158 yfmC M Periplasmic binding protein
KLOEOPPO_00171 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KLOEOPPO_00172 6.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
KLOEOPPO_00173 3.3e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KLOEOPPO_00174 1.1e-90 bioY S BioY family
KLOEOPPO_00175 1.4e-181 hemAT NT chemotaxis protein
KLOEOPPO_00176 1e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KLOEOPPO_00177 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_00178 1.3e-32 yhzC S IDEAL
KLOEOPPO_00179 9.3e-109 comK K Competence transcription factor
KLOEOPPO_00180 8e-168 IQ Enoyl-(Acyl carrier protein) reductase
KLOEOPPO_00181 1.1e-40 yhjA S Excalibur calcium-binding domain
KLOEOPPO_00182 2e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLOEOPPO_00183 6.9e-27 yhjC S Protein of unknown function (DUF3311)
KLOEOPPO_00184 2.5e-59 yhjD
KLOEOPPO_00185 9.1e-110 yhjE S SNARE associated Golgi protein
KLOEOPPO_00186 1e-90 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KLOEOPPO_00187 1.1e-281 yhjG CH FAD binding domain
KLOEOPPO_00188 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
KLOEOPPO_00189 3.8e-213 glcP G Major Facilitator Superfamily
KLOEOPPO_00190 7.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
KLOEOPPO_00191 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
KLOEOPPO_00192 6.3e-254 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
KLOEOPPO_00193 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
KLOEOPPO_00194 1.9e-201 abrB S membrane
KLOEOPPO_00195 4.2e-212 EGP Transmembrane secretion effector
KLOEOPPO_00196 0.0 S Sugar transport-related sRNA regulator N-term
KLOEOPPO_00197 8.4e-78 yhjR S Rubrerythrin
KLOEOPPO_00198 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KLOEOPPO_00199 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KLOEOPPO_00200 3.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KLOEOPPO_00201 0.0 sbcC L COG0419 ATPase involved in DNA repair
KLOEOPPO_00202 1.1e-49 yisB V COG1403 Restriction endonuclease
KLOEOPPO_00203 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
KLOEOPPO_00204 3e-66 gerPE S Spore germination protein GerPE
KLOEOPPO_00205 6.3e-24 gerPD S Spore germination protein
KLOEOPPO_00206 5.3e-54 gerPC S Spore germination protein
KLOEOPPO_00207 4e-34 gerPB S cell differentiation
KLOEOPPO_00208 1.9e-33 gerPA S Spore germination protein
KLOEOPPO_00209 1.5e-22 yisI S Spo0E like sporulation regulatory protein
KLOEOPPO_00210 1.2e-171 cotH M Spore Coat
KLOEOPPO_00211 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KLOEOPPO_00212 3.9e-57 yisL S UPF0344 protein
KLOEOPPO_00213 0.0 wprA O Belongs to the peptidase S8 family
KLOEOPPO_00214 1.3e-102 yisN S Protein of unknown function (DUF2777)
KLOEOPPO_00215 0.0 asnO 6.3.5.4 E Asparagine synthase
KLOEOPPO_00216 4.7e-88 yizA S Damage-inducible protein DinB
KLOEOPPO_00217 2.8e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KLOEOPPO_00218 1.5e-242 yisQ V Mate efflux family protein
KLOEOPPO_00219 1.2e-160 yisR K Transcriptional regulator
KLOEOPPO_00220 6.9e-184 purR K helix_turn _helix lactose operon repressor
KLOEOPPO_00221 5.2e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
KLOEOPPO_00222 7e-92 yisT S DinB family
KLOEOPPO_00223 1.4e-99 argO S Lysine exporter protein LysE YggA
KLOEOPPO_00224 5.8e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KLOEOPPO_00225 6.8e-36 mcbG S Pentapeptide repeats (9 copies)
KLOEOPPO_00226 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KLOEOPPO_00227 1.4e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
KLOEOPPO_00228 7.4e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KLOEOPPO_00229 2.1e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KLOEOPPO_00230 1.1e-119 comB 3.1.3.71 H Belongs to the ComB family
KLOEOPPO_00231 1.9e-141 yitD 4.4.1.19 S synthase
KLOEOPPO_00232 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KLOEOPPO_00233 4.6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KLOEOPPO_00234 1.5e-228 yitG EGP Major facilitator Superfamily
KLOEOPPO_00235 4.8e-154 yitH K Acetyltransferase (GNAT) domain
KLOEOPPO_00236 1.3e-70 yjcF S Acetyltransferase (GNAT) domain
KLOEOPPO_00237 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KLOEOPPO_00238 3.3e-54 yajQ S Belongs to the UPF0234 family
KLOEOPPO_00239 4e-161 cvfB S protein conserved in bacteria
KLOEOPPO_00240 8.5e-94
KLOEOPPO_00241 3.6e-171
KLOEOPPO_00242 1.5e-97 S Sporulation delaying protein SdpA
KLOEOPPO_00243 1.5e-58 K Transcriptional regulator PadR-like family
KLOEOPPO_00244 5e-94
KLOEOPPO_00245 1.4e-44 yitR S Domain of unknown function (DUF3784)
KLOEOPPO_00246 2.7e-307 nprB 3.4.24.28 E Peptidase M4
KLOEOPPO_00247 8.4e-159 yitS S protein conserved in bacteria
KLOEOPPO_00248 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KLOEOPPO_00249 5e-73 ipi S Intracellular proteinase inhibitor
KLOEOPPO_00250 1.2e-17 S Protein of unknown function (DUF3813)
KLOEOPPO_00252 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KLOEOPPO_00253 3.8e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KLOEOPPO_00254 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
KLOEOPPO_00255 1.5e-22 pilT S Proteolipid membrane potential modulator
KLOEOPPO_00256 8.3e-268 yitY C D-arabinono-1,4-lactone oxidase
KLOEOPPO_00257 1.7e-88 norB G Major Facilitator Superfamily
KLOEOPPO_00258 1.8e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KLOEOPPO_00259 6.5e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KLOEOPPO_00260 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KLOEOPPO_00261 5.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KLOEOPPO_00262 1.1e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KLOEOPPO_00263 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KLOEOPPO_00264 8.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KLOEOPPO_00265 9.5e-28 yjzC S YjzC-like protein
KLOEOPPO_00266 2.3e-16 yjzD S Protein of unknown function (DUF2929)
KLOEOPPO_00267 1.1e-141 yjaU I carboxylic ester hydrolase activity
KLOEOPPO_00268 3.4e-100 yjaV
KLOEOPPO_00269 1.2e-182 med S Transcriptional activator protein med
KLOEOPPO_00270 7.3e-26 comZ S ComZ
KLOEOPPO_00271 2.7e-22 yjzB
KLOEOPPO_00272 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLOEOPPO_00273 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KLOEOPPO_00274 1.1e-149 yjaZ O Zn-dependent protease
KLOEOPPO_00275 1.8e-184 appD P Belongs to the ABC transporter superfamily
KLOEOPPO_00276 4.2e-186 appF E Belongs to the ABC transporter superfamily
KLOEOPPO_00277 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KLOEOPPO_00278 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLOEOPPO_00279 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLOEOPPO_00280 5e-147 yjbA S Belongs to the UPF0736 family
KLOEOPPO_00281 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KLOEOPPO_00282 0.0 oppA E ABC transporter substrate-binding protein
KLOEOPPO_00283 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLOEOPPO_00284 1e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLOEOPPO_00285 3.4e-197 oppD P Belongs to the ABC transporter superfamily
KLOEOPPO_00286 5.5e-172 oppF E Belongs to the ABC transporter superfamily
KLOEOPPO_00287 5.4e-210 yjbB EGP Major Facilitator Superfamily
KLOEOPPO_00288 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLOEOPPO_00289 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KLOEOPPO_00290 6e-112 yjbE P Integral membrane protein TerC family
KLOEOPPO_00291 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KLOEOPPO_00292 2.3e-223 yjbF S Competence protein
KLOEOPPO_00293 0.0 pepF E oligoendopeptidase F
KLOEOPPO_00294 1.8e-20
KLOEOPPO_00296 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KLOEOPPO_00297 3.7e-72 yjbI S Bacterial-like globin
KLOEOPPO_00298 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KLOEOPPO_00299 2.4e-101 yjbK S protein conserved in bacteria
KLOEOPPO_00300 7.1e-62 yjbL S Belongs to the UPF0738 family
KLOEOPPO_00301 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
KLOEOPPO_00302 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLOEOPPO_00303 1.2e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLOEOPPO_00304 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KLOEOPPO_00305 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KLOEOPPO_00306 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KLOEOPPO_00307 1.9e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KLOEOPPO_00308 2.3e-217 thiO 1.4.3.19 E Glycine oxidase
KLOEOPPO_00309 6.7e-30 thiS H thiamine diphosphate biosynthetic process
KLOEOPPO_00310 4.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KLOEOPPO_00311 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KLOEOPPO_00312 5.4e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KLOEOPPO_00313 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KLOEOPPO_00314 1.4e-52 yjbX S Spore coat protein
KLOEOPPO_00315 8.9e-83 cotZ S Spore coat protein
KLOEOPPO_00316 7.6e-96 cotY S Spore coat protein Z
KLOEOPPO_00317 1.2e-67 cotX S Spore Coat Protein X and V domain
KLOEOPPO_00318 7.4e-23 cotW
KLOEOPPO_00319 7.2e-49 cotV S Spore Coat Protein X and V domain
KLOEOPPO_00320 4.3e-56 yjcA S Protein of unknown function (DUF1360)
KLOEOPPO_00323 2.9e-38 spoVIF S Stage VI sporulation protein F
KLOEOPPO_00324 0.0 yjcD 3.6.4.12 L DNA helicase
KLOEOPPO_00325 1.7e-38
KLOEOPPO_00326 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLOEOPPO_00327 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KLOEOPPO_00328 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
KLOEOPPO_00329 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KLOEOPPO_00330 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KLOEOPPO_00331 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
KLOEOPPO_00332 1.3e-210 yjcL S Protein of unknown function (DUF819)
KLOEOPPO_00335 1.6e-38
KLOEOPPO_00336 1e-29
KLOEOPPO_00337 5e-238 M nucleic acid phosphodiester bond hydrolysis
KLOEOPPO_00339 1.4e-29 KLT Protein tyrosine kinase
KLOEOPPO_00340 4.3e-11 S YolD-like protein
KLOEOPPO_00341 1.9e-36
KLOEOPPO_00342 9e-19
KLOEOPPO_00344 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
KLOEOPPO_00345 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
KLOEOPPO_00347 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KLOEOPPO_00348 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KLOEOPPO_00349 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
KLOEOPPO_00350 4.1e-50 yjdF S Protein of unknown function (DUF2992)
KLOEOPPO_00351 9e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
KLOEOPPO_00353 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KLOEOPPO_00354 4.2e-29 S Domain of unknown function (DUF4177)
KLOEOPPO_00355 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
KLOEOPPO_00356 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KLOEOPPO_00358 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
KLOEOPPO_00359 5.5e-83 S Protein of unknown function (DUF2690)
KLOEOPPO_00360 2.3e-20 yjfB S Putative motility protein
KLOEOPPO_00361 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
KLOEOPPO_00362 1.2e-45 T PhoQ Sensor
KLOEOPPO_00363 8.9e-104 yjgB S Domain of unknown function (DUF4309)
KLOEOPPO_00364 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KLOEOPPO_00365 4.3e-95 yjgD S Protein of unknown function (DUF1641)
KLOEOPPO_00366 8.7e-07 S Domain of unknown function (DUF4352)
KLOEOPPO_00367 2.8e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KLOEOPPO_00369 4.9e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KLOEOPPO_00370 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KLOEOPPO_00371 8.2e-30
KLOEOPPO_00372 1.4e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KLOEOPPO_00373 1.9e-122 ybbM S transport system, permease component
KLOEOPPO_00374 3.7e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
KLOEOPPO_00375 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
KLOEOPPO_00376 4e-92 yjlB S Cupin domain
KLOEOPPO_00377 7.1e-66 yjlC S Protein of unknown function (DUF1641)
KLOEOPPO_00378 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
KLOEOPPO_00379 3.5e-279 uxaC 5.3.1.12 G glucuronate isomerase
KLOEOPPO_00380 1.1e-248 yjmB G symporter YjmB
KLOEOPPO_00381 2.2e-190 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KLOEOPPO_00382 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KLOEOPPO_00383 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KLOEOPPO_00384 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KLOEOPPO_00385 3.7e-227 exuT G Sugar (and other) transporter
KLOEOPPO_00386 2.3e-184 exuR K transcriptional
KLOEOPPO_00387 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KLOEOPPO_00388 4.6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KLOEOPPO_00389 7.4e-130 MA20_18170 S membrane transporter protein
KLOEOPPO_00390 2.3e-78 yjoA S DinB family
KLOEOPPO_00391 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
KLOEOPPO_00392 1e-212 S response regulator aspartate phosphatase
KLOEOPPO_00394 6.3e-41 S YCII-related domain
KLOEOPPO_00395 2.9e-168 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
KLOEOPPO_00396 1.8e-60 yjqA S Bacterial PH domain
KLOEOPPO_00397 2.1e-111 yjqB S Pfam:DUF867
KLOEOPPO_00398 4.4e-160 ydbD P Catalase
KLOEOPPO_00399 4.3e-109 xkdA E IrrE N-terminal-like domain
KLOEOPPO_00400 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
KLOEOPPO_00402 5e-156 xkdB K sequence-specific DNA binding
KLOEOPPO_00403 9.2e-118 xkdC L Bacterial dnaA protein
KLOEOPPO_00406 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
KLOEOPPO_00407 2.2e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KLOEOPPO_00408 5.3e-139 xtmA L phage terminase small subunit
KLOEOPPO_00409 1.4e-253 xtmB S phage terminase, large subunit
KLOEOPPO_00410 6e-285 yqbA S portal protein
KLOEOPPO_00411 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KLOEOPPO_00412 1.3e-168 xkdG S Phage capsid family
KLOEOPPO_00413 5.5e-65 yqbG S Protein of unknown function (DUF3199)
KLOEOPPO_00414 8.7e-65 yqbH S Domain of unknown function (DUF3599)
KLOEOPPO_00415 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
KLOEOPPO_00416 5.5e-77 xkdJ
KLOEOPPO_00417 2.5e-256 xkdK S Phage tail sheath C-terminal domain
KLOEOPPO_00418 6.1e-76 xkdM S Phage tail tube protein
KLOEOPPO_00419 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
KLOEOPPO_00420 0.0 xkdO L Transglycosylase SLT domain
KLOEOPPO_00421 3.7e-122 xkdP S Lysin motif
KLOEOPPO_00422 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
KLOEOPPO_00423 2.1e-39 xkdR S Protein of unknown function (DUF2577)
KLOEOPPO_00424 9.6e-71 xkdS S Protein of unknown function (DUF2634)
KLOEOPPO_00425 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KLOEOPPO_00426 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KLOEOPPO_00427 6.7e-41
KLOEOPPO_00428 0.0
KLOEOPPO_00429 2.6e-55 xkdW S XkdW protein
KLOEOPPO_00430 1.7e-23 xkdX
KLOEOPPO_00431 2.1e-154 xepA
KLOEOPPO_00432 2.8e-39 xhlA S Haemolysin XhlA
KLOEOPPO_00433 9.3e-40 xhlB S SPP1 phage holin
KLOEOPPO_00434 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KLOEOPPO_00435 6.7e-23 spoIISB S Stage II sporulation protein SB
KLOEOPPO_00436 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KLOEOPPO_00437 5.8e-175 pit P phosphate transporter
KLOEOPPO_00438 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KLOEOPPO_00439 9.4e-242 steT E amino acid
KLOEOPPO_00440 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KLOEOPPO_00442 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KLOEOPPO_00443 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KLOEOPPO_00445 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KLOEOPPO_00446 3.7e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
KLOEOPPO_00447 4.3e-152 dppA E D-aminopeptidase
KLOEOPPO_00448 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLOEOPPO_00449 3.6e-174 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KLOEOPPO_00450 1.9e-186 dppD P Belongs to the ABC transporter superfamily
KLOEOPPO_00451 0.0 dppE E ABC transporter substrate-binding protein
KLOEOPPO_00453 1.2e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KLOEOPPO_00454 7.5e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KLOEOPPO_00455 2.2e-165 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KLOEOPPO_00456 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
KLOEOPPO_00457 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
KLOEOPPO_00458 5.3e-161 ykgA E Amidinotransferase
KLOEOPPO_00459 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KLOEOPPO_00460 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KLOEOPPO_00461 1e-07
KLOEOPPO_00462 2.7e-129 ykjA S Protein of unknown function (DUF421)
KLOEOPPO_00463 1e-98 ykkA S Protein of unknown function (DUF664)
KLOEOPPO_00464 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KLOEOPPO_00465 3.5e-55 ykkC P Multidrug resistance protein
KLOEOPPO_00466 7e-50 ykkD P Multidrug resistance protein
KLOEOPPO_00467 1.2e-168 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KLOEOPPO_00468 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLOEOPPO_00469 6.9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KLOEOPPO_00471 1.3e-70 ohrA O Organic hydroperoxide resistance protein
KLOEOPPO_00472 4.8e-73 ohrR K COG1846 Transcriptional regulators
KLOEOPPO_00473 8.4e-72 ohrB O Organic hydroperoxide resistance protein
KLOEOPPO_00475 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
KLOEOPPO_00476 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KLOEOPPO_00477 5e-176 isp O Belongs to the peptidase S8 family
KLOEOPPO_00478 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KLOEOPPO_00479 5.3e-136 ykoC P Cobalt transport protein
KLOEOPPO_00480 2.2e-304 P ABC transporter, ATP-binding protein
KLOEOPPO_00481 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
KLOEOPPO_00482 1.3e-108 ykoF S YKOF-related Family
KLOEOPPO_00483 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_00484 4.1e-240 ykoH 2.7.13.3 T Histidine kinase
KLOEOPPO_00485 1.4e-111 ykoI S Peptidase propeptide and YPEB domain
KLOEOPPO_00486 8.3e-85 ykoJ S Peptidase propeptide and YPEB domain
KLOEOPPO_00489 2.2e-222 mgtE P Acts as a magnesium transporter
KLOEOPPO_00490 1.4e-53 tnrA K transcriptional
KLOEOPPO_00491 5.9e-18
KLOEOPPO_00492 6.9e-26 ykoL
KLOEOPPO_00493 1.3e-81 mhqR K transcriptional
KLOEOPPO_00494 8.9e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KLOEOPPO_00495 3.7e-99 ykoP G polysaccharide deacetylase
KLOEOPPO_00496 2.1e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
KLOEOPPO_00497 0.0 ykoS
KLOEOPPO_00498 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KLOEOPPO_00499 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KLOEOPPO_00500 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KLOEOPPO_00501 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
KLOEOPPO_00502 2.7e-109 ykoX S membrane-associated protein
KLOEOPPO_00503 6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KLOEOPPO_00504 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KLOEOPPO_00505 4.8e-117 rsgI S Anti-sigma factor N-terminus
KLOEOPPO_00506 1.9e-26 sspD S small acid-soluble spore protein
KLOEOPPO_00507 1.9e-124 ykrK S Domain of unknown function (DUF1836)
KLOEOPPO_00508 1.3e-154 htpX O Belongs to the peptidase M48B family
KLOEOPPO_00509 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
KLOEOPPO_00510 1.2e-10 ydfR S Protein of unknown function (DUF421)
KLOEOPPO_00511 4.1e-18 ykzE
KLOEOPPO_00512 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KLOEOPPO_00513 0.0 kinE 2.7.13.3 T Histidine kinase
KLOEOPPO_00514 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KLOEOPPO_00516 8.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KLOEOPPO_00517 8.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KLOEOPPO_00518 2.3e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KLOEOPPO_00519 1.5e-230 mtnE 2.6.1.83 E Aminotransferase
KLOEOPPO_00520 8.5e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KLOEOPPO_00521 1.1e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KLOEOPPO_00522 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KLOEOPPO_00523 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KLOEOPPO_00524 2.2e-51 XK27_09985 S Protein of unknown function (DUF1232)
KLOEOPPO_00525 6.4e-09 S Spo0E like sporulation regulatory protein
KLOEOPPO_00526 1.4e-64 eag
KLOEOPPO_00527 6.3e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KLOEOPPO_00528 1.3e-75 ykvE K transcriptional
KLOEOPPO_00529 2.5e-125 motB N Flagellar motor protein
KLOEOPPO_00530 1e-137 motA N flagellar motor
KLOEOPPO_00531 0.0 clpE O Belongs to the ClpA ClpB family
KLOEOPPO_00532 1.4e-179 ykvI S membrane
KLOEOPPO_00533 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KLOEOPPO_00534 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KLOEOPPO_00535 6.4e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KLOEOPPO_00536 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KLOEOPPO_00537 3.4e-61 ykvN K Transcriptional regulator
KLOEOPPO_00538 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
KLOEOPPO_00539 2.4e-214 ykvP 3.5.1.28 M Glycosyl transferases group 1
KLOEOPPO_00540 3.5e-35 3.5.1.104 M LysM domain
KLOEOPPO_00541 2e-161 G Glycosyl hydrolases family 18
KLOEOPPO_00542 1.4e-44 ykvR S Protein of unknown function (DUF3219)
KLOEOPPO_00543 6e-25 ykvS S protein conserved in bacteria
KLOEOPPO_00544 2.8e-28
KLOEOPPO_00545 2.7e-101 ykvT 3.5.1.28 M Cell Wall Hydrolase
KLOEOPPO_00546 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KLOEOPPO_00547 3.5e-88 stoA CO thiol-disulfide
KLOEOPPO_00548 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KLOEOPPO_00549 1.4e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KLOEOPPO_00550 1.2e-177 ykvZ 5.1.1.1 K Transcriptional regulator
KLOEOPPO_00552 7.6e-128 glcT K antiterminator
KLOEOPPO_00553 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KLOEOPPO_00554 2.1e-39 ptsH G phosphocarrier protein HPr
KLOEOPPO_00555 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLOEOPPO_00556 7.2e-39 splA S Transcriptional regulator
KLOEOPPO_00557 3.7e-201 splB 4.1.99.14 L Spore photoproduct lyase
KLOEOPPO_00558 4.9e-128 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLOEOPPO_00559 1.6e-261 mcpC NT chemotaxis protein
KLOEOPPO_00560 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KLOEOPPO_00561 8e-124 ykwD J protein with SCP PR1 domains
KLOEOPPO_00562 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KLOEOPPO_00563 0.0 pilS 2.7.13.3 T Histidine kinase
KLOEOPPO_00564 1.8e-220 patA 2.6.1.1 E Aminotransferase
KLOEOPPO_00565 2.2e-15
KLOEOPPO_00566 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
KLOEOPPO_00567 1.7e-84 ykyB S YkyB-like protein
KLOEOPPO_00568 4.8e-238 ykuC EGP Major facilitator Superfamily
KLOEOPPO_00569 1.5e-86 ykuD S protein conserved in bacteria
KLOEOPPO_00570 4.7e-165 ykuE S Metallophosphoesterase
KLOEOPPO_00571 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_00572 0.0 3.2.1.132 M Putative peptidoglycan binding domain
KLOEOPPO_00574 5.2e-234 ykuI T Diguanylate phosphodiesterase
KLOEOPPO_00575 3.9e-37 ykuJ S protein conserved in bacteria
KLOEOPPO_00576 4.4e-94 ykuK S Ribonuclease H-like
KLOEOPPO_00577 3.9e-27 ykzF S Antirepressor AbbA
KLOEOPPO_00578 1.6e-76 ykuL S CBS domain
KLOEOPPO_00579 3.5e-168 ccpC K Transcriptional regulator
KLOEOPPO_00580 8.5e-84 fld C Flavodoxin domain
KLOEOPPO_00581 3e-175 ykuO
KLOEOPPO_00582 3.9e-78 fld C Flavodoxin
KLOEOPPO_00583 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KLOEOPPO_00584 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KLOEOPPO_00585 9e-37 ykuS S Belongs to the UPF0180 family
KLOEOPPO_00586 8.8e-142 ykuT M Mechanosensitive ion channel
KLOEOPPO_00587 3.9e-101 ykuU O Alkyl hydroperoxide reductase
KLOEOPPO_00588 6.3e-81 ykuV CO thiol-disulfide
KLOEOPPO_00589 5.8e-95 rok K Repressor of ComK
KLOEOPPO_00590 7.1e-146 yknT
KLOEOPPO_00591 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KLOEOPPO_00592 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KLOEOPPO_00593 2.4e-245 moeA 2.10.1.1 H molybdopterin
KLOEOPPO_00594 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KLOEOPPO_00595 2.7e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KLOEOPPO_00596 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KLOEOPPO_00597 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
KLOEOPPO_00598 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
KLOEOPPO_00599 2.9e-117 yknW S Yip1 domain
KLOEOPPO_00600 3.6e-157 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KLOEOPPO_00601 2.5e-124 macB V ABC transporter, ATP-binding protein
KLOEOPPO_00602 5.6e-209 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
KLOEOPPO_00603 3.1e-136 fruR K Transcriptional regulator
KLOEOPPO_00604 3.1e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KLOEOPPO_00605 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KLOEOPPO_00606 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KLOEOPPO_00607 8.1e-39 ykoA
KLOEOPPO_00608 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KLOEOPPO_00609 5.3e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLOEOPPO_00610 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KLOEOPPO_00611 1.1e-12 S Uncharacterized protein YkpC
KLOEOPPO_00612 7.7e-183 mreB D Rod-share determining protein MreBH
KLOEOPPO_00613 1.5e-43 abrB K of stationary sporulation gene expression
KLOEOPPO_00614 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KLOEOPPO_00615 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KLOEOPPO_00616 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
KLOEOPPO_00617 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KLOEOPPO_00618 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLOEOPPO_00619 8.2e-31 ykzG S Belongs to the UPF0356 family
KLOEOPPO_00620 1.6e-146 ykrA S hydrolases of the HAD superfamily
KLOEOPPO_00621 1.5e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KLOEOPPO_00623 2e-115 recN L Putative cell-wall binding lipoprotein
KLOEOPPO_00624 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KLOEOPPO_00625 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KLOEOPPO_00626 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KLOEOPPO_00627 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KLOEOPPO_00628 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KLOEOPPO_00629 3.5e-277 speA 4.1.1.19 E Arginine
KLOEOPPO_00630 1.6e-42 yktA S Belongs to the UPF0223 family
KLOEOPPO_00631 7.1e-118 yktB S Belongs to the UPF0637 family
KLOEOPPO_00632 7.1e-26 ykzI
KLOEOPPO_00633 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
KLOEOPPO_00634 6.9e-78 ykzC S Acetyltransferase (GNAT) family
KLOEOPPO_00635 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KLOEOPPO_00636 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KLOEOPPO_00637 0.0 ylaA
KLOEOPPO_00638 2.7e-42 ylaB
KLOEOPPO_00639 8e-39 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
KLOEOPPO_00640 5.9e-11 sigC S Putative zinc-finger
KLOEOPPO_00641 1.8e-38 ylaE
KLOEOPPO_00642 8.2e-22 S Family of unknown function (DUF5325)
KLOEOPPO_00643 0.0 typA T GTP-binding protein TypA
KLOEOPPO_00644 4.2e-47 ylaH S YlaH-like protein
KLOEOPPO_00645 2.5e-32 ylaI S protein conserved in bacteria
KLOEOPPO_00646 5.2e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KLOEOPPO_00647 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KLOEOPPO_00648 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KLOEOPPO_00649 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
KLOEOPPO_00650 8.7e-44 ylaN S Belongs to the UPF0358 family
KLOEOPPO_00651 4.5e-214 ftsW D Belongs to the SEDS family
KLOEOPPO_00652 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KLOEOPPO_00653 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KLOEOPPO_00654 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KLOEOPPO_00655 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KLOEOPPO_00656 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KLOEOPPO_00657 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KLOEOPPO_00658 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KLOEOPPO_00659 3e-167 ctaG S cytochrome c oxidase
KLOEOPPO_00660 7e-62 ylbA S YugN-like family
KLOEOPPO_00661 2.6e-74 ylbB T COG0517 FOG CBS domain
KLOEOPPO_00662 5.1e-201 ylbC S protein with SCP PR1 domains
KLOEOPPO_00663 4.1e-63 ylbD S Putative coat protein
KLOEOPPO_00664 6.7e-37 ylbE S YlbE-like protein
KLOEOPPO_00665 1.8e-75 ylbF S Belongs to the UPF0342 family
KLOEOPPO_00666 7.5e-39 ylbG S UPF0298 protein
KLOEOPPO_00667 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
KLOEOPPO_00668 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KLOEOPPO_00669 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
KLOEOPPO_00670 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
KLOEOPPO_00671 6.8e-187 ylbL T Belongs to the peptidase S16 family
KLOEOPPO_00672 2.8e-235 ylbM S Belongs to the UPF0348 family
KLOEOPPO_00674 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
KLOEOPPO_00675 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KLOEOPPO_00676 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KLOEOPPO_00677 4e-89 ylbP K n-acetyltransferase
KLOEOPPO_00678 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLOEOPPO_00679 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KLOEOPPO_00680 2.9e-78 mraZ K Belongs to the MraZ family
KLOEOPPO_00681 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KLOEOPPO_00682 3.7e-44 ftsL D Essential cell division protein
KLOEOPPO_00683 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KLOEOPPO_00684 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KLOEOPPO_00685 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KLOEOPPO_00686 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KLOEOPPO_00687 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KLOEOPPO_00688 5.7e-186 spoVE D Belongs to the SEDS family
KLOEOPPO_00689 2.5e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KLOEOPPO_00690 5.3e-167 murB 1.3.1.98 M cell wall formation
KLOEOPPO_00691 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KLOEOPPO_00692 2.4e-103 ylxW S protein conserved in bacteria
KLOEOPPO_00693 1.4e-91 ylxX S protein conserved in bacteria
KLOEOPPO_00694 6.2e-58 sbp S small basic protein
KLOEOPPO_00695 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KLOEOPPO_00696 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KLOEOPPO_00697 0.0 bpr O COG1404 Subtilisin-like serine proteases
KLOEOPPO_00698 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KLOEOPPO_00699 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KLOEOPPO_00700 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KLOEOPPO_00701 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KLOEOPPO_00702 8.5e-256 argE 3.5.1.16 E Acetylornithine deacetylase
KLOEOPPO_00703 2.4e-37 ylmC S sporulation protein
KLOEOPPO_00704 5.9e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KLOEOPPO_00705 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KLOEOPPO_00706 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KLOEOPPO_00707 1.3e-39 yggT S membrane
KLOEOPPO_00708 1.7e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KLOEOPPO_00709 2.6e-67 divIVA D Cell division initiation protein
KLOEOPPO_00710 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KLOEOPPO_00711 1.3e-63 dksA T COG1734 DnaK suppressor protein
KLOEOPPO_00712 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KLOEOPPO_00713 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLOEOPPO_00714 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KLOEOPPO_00715 1.1e-229 pyrP F Xanthine uracil
KLOEOPPO_00716 2.3e-156 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KLOEOPPO_00717 2e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KLOEOPPO_00718 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KLOEOPPO_00719 0.0 carB 6.3.5.5 F Belongs to the CarB family
KLOEOPPO_00720 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KLOEOPPO_00721 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KLOEOPPO_00722 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KLOEOPPO_00723 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLOEOPPO_00725 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KLOEOPPO_00726 1.1e-179 cysP P phosphate transporter
KLOEOPPO_00727 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KLOEOPPO_00728 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KLOEOPPO_00729 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KLOEOPPO_00730 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KLOEOPPO_00731 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KLOEOPPO_00732 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KLOEOPPO_00733 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KLOEOPPO_00734 2.4e-156 yloC S stress-induced protein
KLOEOPPO_00735 1.5e-40 ylzA S Belongs to the UPF0296 family
KLOEOPPO_00736 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KLOEOPPO_00737 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KLOEOPPO_00738 1.8e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KLOEOPPO_00739 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KLOEOPPO_00740 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KLOEOPPO_00741 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KLOEOPPO_00742 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KLOEOPPO_00743 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KLOEOPPO_00744 2.4e-141 stp 3.1.3.16 T phosphatase
KLOEOPPO_00745 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KLOEOPPO_00746 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KLOEOPPO_00747 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KLOEOPPO_00748 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
KLOEOPPO_00749 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KLOEOPPO_00750 5.5e-59 asp S protein conserved in bacteria
KLOEOPPO_00751 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
KLOEOPPO_00752 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
KLOEOPPO_00753 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
KLOEOPPO_00754 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KLOEOPPO_00755 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KLOEOPPO_00756 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KLOEOPPO_00757 2.2e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KLOEOPPO_00758 6.1e-129 IQ reductase
KLOEOPPO_00759 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLOEOPPO_00760 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KLOEOPPO_00761 0.0 smc D Required for chromosome condensation and partitioning
KLOEOPPO_00762 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KLOEOPPO_00763 2.9e-87
KLOEOPPO_00764 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KLOEOPPO_00765 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLOEOPPO_00766 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KLOEOPPO_00767 4.5e-36 ylqC S Belongs to the UPF0109 family
KLOEOPPO_00768 3.1e-60 ylqD S YlqD protein
KLOEOPPO_00769 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KLOEOPPO_00770 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KLOEOPPO_00771 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KLOEOPPO_00772 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KLOEOPPO_00773 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLOEOPPO_00774 6.9e-285 ylqG
KLOEOPPO_00775 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KLOEOPPO_00776 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KLOEOPPO_00777 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KLOEOPPO_00778 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KLOEOPPO_00779 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLOEOPPO_00780 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KLOEOPPO_00781 2.5e-169 xerC L tyrosine recombinase XerC
KLOEOPPO_00782 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KLOEOPPO_00783 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KLOEOPPO_00784 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KLOEOPPO_00785 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KLOEOPPO_00786 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
KLOEOPPO_00787 1.9e-31 fliE N Flagellar hook-basal body
KLOEOPPO_00788 2.6e-254 fliF N The M ring may be actively involved in energy transduction
KLOEOPPO_00789 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KLOEOPPO_00790 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KLOEOPPO_00791 4.7e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KLOEOPPO_00792 1.5e-69 fliJ N Flagellar biosynthesis chaperone
KLOEOPPO_00793 7.7e-37 ylxF S MgtE intracellular N domain
KLOEOPPO_00794 7.6e-216 fliK N Flagellar hook-length control protein
KLOEOPPO_00795 1.7e-72 flgD N Flagellar basal body rod modification protein
KLOEOPPO_00796 8.2e-140 flgG N Flagellar basal body rod
KLOEOPPO_00797 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
KLOEOPPO_00798 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KLOEOPPO_00799 8e-173 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KLOEOPPO_00800 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KLOEOPPO_00801 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
KLOEOPPO_00802 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
KLOEOPPO_00803 2.2e-36 fliQ N Role in flagellar biosynthesis
KLOEOPPO_00804 3.6e-132 fliR N Flagellar biosynthetic protein FliR
KLOEOPPO_00805 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KLOEOPPO_00806 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KLOEOPPO_00807 5.7e-200 flhF N Flagellar biosynthesis regulator FlhF
KLOEOPPO_00808 7.5e-158 flhG D Belongs to the ParA family
KLOEOPPO_00809 6.4e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KLOEOPPO_00810 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KLOEOPPO_00811 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
KLOEOPPO_00812 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KLOEOPPO_00813 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KLOEOPPO_00814 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KLOEOPPO_00815 4.3e-78 ylxL
KLOEOPPO_00816 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
KLOEOPPO_00817 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KLOEOPPO_00818 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KLOEOPPO_00819 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KLOEOPPO_00820 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KLOEOPPO_00821 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
KLOEOPPO_00822 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KLOEOPPO_00823 7.7e-233 rasP M zinc metalloprotease
KLOEOPPO_00824 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KLOEOPPO_00825 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLOEOPPO_00826 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
KLOEOPPO_00827 1.1e-203 nusA K Participates in both transcription termination and antitermination
KLOEOPPO_00828 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
KLOEOPPO_00829 3.1e-47 ylxQ J ribosomal protein
KLOEOPPO_00830 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KLOEOPPO_00831 3e-44 ylxP S protein conserved in bacteria
KLOEOPPO_00832 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KLOEOPPO_00833 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KLOEOPPO_00834 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KLOEOPPO_00835 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KLOEOPPO_00836 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KLOEOPPO_00837 2.8e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KLOEOPPO_00838 4.4e-233 pepR S Belongs to the peptidase M16 family
KLOEOPPO_00839 2.6e-42 ymxH S YlmC YmxH family
KLOEOPPO_00840 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KLOEOPPO_00841 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KLOEOPPO_00842 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KLOEOPPO_00843 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KLOEOPPO_00844 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KLOEOPPO_00845 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLOEOPPO_00846 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KLOEOPPO_00847 1.4e-30 S YlzJ-like protein
KLOEOPPO_00848 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KLOEOPPO_00849 1.4e-133 ymfC K Transcriptional regulator
KLOEOPPO_00850 1.5e-206 ymfD EGP Major facilitator Superfamily
KLOEOPPO_00851 2.9e-235 ymfF S Peptidase M16
KLOEOPPO_00852 1.4e-242 ymfH S zinc protease
KLOEOPPO_00853 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KLOEOPPO_00854 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
KLOEOPPO_00855 2.7e-143 ymfK S Protein of unknown function (DUF3388)
KLOEOPPO_00856 1.9e-124 ymfM S protein conserved in bacteria
KLOEOPPO_00857 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLOEOPPO_00858 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
KLOEOPPO_00859 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KLOEOPPO_00860 1.4e-215 pbpX V Beta-lactamase
KLOEOPPO_00861 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
KLOEOPPO_00862 1.9e-152 ymdB S protein conserved in bacteria
KLOEOPPO_00863 1.2e-36 spoVS S Stage V sporulation protein S
KLOEOPPO_00864 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KLOEOPPO_00865 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KLOEOPPO_00866 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KLOEOPPO_00867 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KLOEOPPO_00868 2.2e-88 cotE S Spore coat protein
KLOEOPPO_00869 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLOEOPPO_00870 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLOEOPPO_00871 2.3e-70 S Regulatory protein YrvL
KLOEOPPO_00873 1.2e-97 ymcC S Membrane
KLOEOPPO_00874 4.4e-109 pksA K Transcriptional regulator
KLOEOPPO_00875 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
KLOEOPPO_00876 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KLOEOPPO_00877 2.4e-186 pksD Q Acyl transferase domain
KLOEOPPO_00878 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KLOEOPPO_00879 1.4e-37 acpK IQ Phosphopantetheine attachment site
KLOEOPPO_00880 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KLOEOPPO_00881 1.3e-245 pksG 2.3.3.10 I synthase
KLOEOPPO_00882 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
KLOEOPPO_00883 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KLOEOPPO_00884 0.0 rhiB IQ polyketide synthase
KLOEOPPO_00885 0.0 pfaA Q Polyketide synthase of type I
KLOEOPPO_00886 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
KLOEOPPO_00887 0.0 dhbF IQ polyketide synthase
KLOEOPPO_00888 0.0 pks13 HQ Beta-ketoacyl synthase
KLOEOPPO_00889 2.8e-232 cypA C Cytochrome P450
KLOEOPPO_00890 4.4e-61 ymzB
KLOEOPPO_00891 2.3e-161 ymaE S Metallo-beta-lactamase superfamily
KLOEOPPO_00892 2.8e-249 aprX O Belongs to the peptidase S8 family
KLOEOPPO_00893 1.9e-07 K Transcriptional regulator
KLOEOPPO_00894 2.1e-126 ymaC S Replication protein
KLOEOPPO_00895 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
KLOEOPPO_00896 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
KLOEOPPO_00897 9.2e-50 ebrA P Small Multidrug Resistance protein
KLOEOPPO_00899 2.1e-46 ymaF S YmaF family
KLOEOPPO_00900 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLOEOPPO_00901 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KLOEOPPO_00902 8.2e-23
KLOEOPPO_00903 4.5e-22 ymzA
KLOEOPPO_00904 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KLOEOPPO_00905 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLOEOPPO_00906 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLOEOPPO_00907 2e-109 ymaB
KLOEOPPO_00908 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KLOEOPPO_00909 1.2e-96 spoVK O stage V sporulation protein K
KLOEOPPO_00911 5.8e-81 yhbS S family acetyltransferase
KLOEOPPO_00912 1.9e-108 yokF 3.1.31.1 L RNA catabolic process
KLOEOPPO_00913 7.6e-65 G SMI1-KNR4 cell-wall
KLOEOPPO_00914 1.7e-172 yobL S Bacterial EndoU nuclease
KLOEOPPO_00915 8.2e-76 S SMI1-KNR4 cell-wall
KLOEOPPO_00916 1.8e-91 yokK S SMI1 / KNR4 family
KLOEOPPO_00917 6.8e-100 S aspartate phosphatase
KLOEOPPO_00922 8.4e-54 S YolD-like protein
KLOEOPPO_00923 1.5e-233 S impB/mucB/samB family C-terminal domain
KLOEOPPO_00925 0.0 V Peptidase C39 family
KLOEOPPO_00926 1.2e-70 CO cell redox homeostasis
KLOEOPPO_00927 2.9e-240 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KLOEOPPO_00928 3.4e-74 O protein disulfide oxidoreductase activity
KLOEOPPO_00929 5.5e-40 S SPP1 phage holin
KLOEOPPO_00930 4.4e-32 bhlA S BhlA holin family
KLOEOPPO_00931 5.5e-75 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KLOEOPPO_00932 1e-183 M Pectate lyase superfamily protein
KLOEOPPO_00933 2.2e-119
KLOEOPPO_00934 5.2e-292 S Pfam Transposase IS66
KLOEOPPO_00935 8.5e-86 S Phage tail protein
KLOEOPPO_00936 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KLOEOPPO_00937 3.4e-110
KLOEOPPO_00938 1.1e-17
KLOEOPPO_00941 4.4e-191 xerH A Belongs to the 'phage' integrase family
KLOEOPPO_00942 8.4e-59
KLOEOPPO_00943 2.9e-55
KLOEOPPO_00944 5.7e-99 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
KLOEOPPO_00945 9.3e-08 S Phage uncharacterised protein (Phage_XkdX)
KLOEOPPO_00946 2.1e-08
KLOEOPPO_00947 2.5e-35 S Domain of unknown function (DUF2479)
KLOEOPPO_00948 2.7e-45
KLOEOPPO_00951 1.1e-88
KLOEOPPO_00952 1.4e-130
KLOEOPPO_00953 2.6e-91
KLOEOPPO_00954 1.8e-68
KLOEOPPO_00957 1.9e-70
KLOEOPPO_00959 2.1e-35
KLOEOPPO_00960 3.1e-18
KLOEOPPO_00961 9.6e-109
KLOEOPPO_00962 4.9e-17
KLOEOPPO_00965 8.5e-229 S hydrolase activity
KLOEOPPO_00968 1.1e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KLOEOPPO_00969 0.0
KLOEOPPO_00972 1.3e-51 bldD K domain, Protein
KLOEOPPO_00973 4.3e-16
KLOEOPPO_00975 9.4e-204
KLOEOPPO_00979 3e-09 ywlA S Uncharacterised protein family (UPF0715)
KLOEOPPO_00980 1.4e-80 yoaW
KLOEOPPO_00981 1e-31 K Cro/C1-type HTH DNA-binding domain
KLOEOPPO_00988 5.3e-13
KLOEOPPO_00989 6.2e-31
KLOEOPPO_00992 3.9e-35 V HNH endonuclease
KLOEOPPO_00993 3.3e-105
KLOEOPPO_00998 8.9e-198 L Belongs to the 'phage' integrase family
KLOEOPPO_00999 1.3e-262 S DNA-sulfur modification-associated
KLOEOPPO_01000 1.8e-176
KLOEOPPO_01001 1.1e-33 K Transcriptional regulator
KLOEOPPO_01007 5.3e-17
KLOEOPPO_01012 2.7e-66 2.1.1.294, 2.7.1.181 N bacterial-type flagellum assembly
KLOEOPPO_01022 8.6e-74
KLOEOPPO_01027 6.4e-63
KLOEOPPO_01028 2.5e-07 xtmA L DNA packaging
KLOEOPPO_01029 5.3e-66
KLOEOPPO_01030 4.6e-138 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
KLOEOPPO_01031 2.5e-129 yoqW S Belongs to the SOS response-associated peptidase family
KLOEOPPO_01033 4.5e-163
KLOEOPPO_01038 2.5e-156
KLOEOPPO_01039 7.6e-180 L AAA domain
KLOEOPPO_01040 2e-85
KLOEOPPO_01041 9.7e-283 3.6.4.12 J DnaB-like helicase C terminal domain
KLOEOPPO_01042 2.1e-221 L DNA primase activity
KLOEOPPO_01043 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KLOEOPPO_01044 0.0 S Bacterial DNA polymerase III alpha subunit
KLOEOPPO_01045 4.8e-123 DR0488 S protein conserved in bacteria
KLOEOPPO_01050 1.4e-84 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
KLOEOPPO_01051 8.7e-90 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KLOEOPPO_01053 5.1e-146 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
KLOEOPPO_01059 1.2e-25 S hydrolase activity
KLOEOPPO_01067 3.8e-10 larC 4.99.1.12 FJ Protein conserved in bacteria
KLOEOPPO_01072 2.6e-62 S NrdI Flavodoxin like
KLOEOPPO_01073 0.0 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
KLOEOPPO_01075 4.2e-181 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLOEOPPO_01076 2.2e-35 O Glutaredoxin
KLOEOPPO_01077 1.1e-09
KLOEOPPO_01078 3.6e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KLOEOPPO_01083 1.5e-160 S Thymidylate synthase
KLOEOPPO_01084 5.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KLOEOPPO_01086 7e-36
KLOEOPPO_01089 1.4e-28 sspB S spore protein
KLOEOPPO_01090 9.7e-160 S Calcineurin-like phosphoesterase
KLOEOPPO_01099 4.1e-10 K Cro/C1-type HTH DNA-binding domain
KLOEOPPO_01100 1.1e-93 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KLOEOPPO_01102 5.3e-245 cisA2 L Recombinase
KLOEOPPO_01103 8.7e-69 spoVK O stage V sporulation protein K
KLOEOPPO_01104 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KLOEOPPO_01105 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KLOEOPPO_01106 1.1e-68 glnR K transcriptional
KLOEOPPO_01107 7e-261 glnA 6.3.1.2 E glutamine synthetase
KLOEOPPO_01108 5e-10
KLOEOPPO_01109 2.5e-32
KLOEOPPO_01110 5.8e-39
KLOEOPPO_01111 6.8e-80 G regulation of fungal-type cell wall biogenesis
KLOEOPPO_01112 4.9e-145 ynaC
KLOEOPPO_01113 2e-99 ynaD J Acetyltransferase (GNAT) domain
KLOEOPPO_01114 1.9e-123 ynaE S Domain of unknown function (DUF3885)
KLOEOPPO_01115 6.4e-60 ynaF
KLOEOPPO_01118 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
KLOEOPPO_01119 2.5e-253 xynT G MFS/sugar transport protein
KLOEOPPO_01120 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
KLOEOPPO_01121 6.2e-213 xylR GK ROK family
KLOEOPPO_01122 2e-263 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KLOEOPPO_01123 3.3e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
KLOEOPPO_01124 6.4e-111 yokF 3.1.31.1 L RNA catabolic process
KLOEOPPO_01125 6.8e-254 iolT EGP Major facilitator Superfamily
KLOEOPPO_01126 1.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KLOEOPPO_01127 5e-81 yncE S Protein of unknown function (DUF2691)
KLOEOPPO_01128 5.3e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KLOEOPPO_01129 5.2e-15
KLOEOPPO_01132 9.5e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLOEOPPO_01134 1.3e-134 S Domain of unknown function, YrpD
KLOEOPPO_01137 7.9e-25 tatA U protein secretion
KLOEOPPO_01138 1.8e-71
KLOEOPPO_01139 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
KLOEOPPO_01142 7.4e-286 gerAA EG Spore germination protein
KLOEOPPO_01143 4.5e-197 gerAB U Spore germination
KLOEOPPO_01144 4.2e-220 gerLC S Spore germination protein
KLOEOPPO_01145 7.7e-154 yndG S DoxX-like family
KLOEOPPO_01146 2.6e-117 yndH S Domain of unknown function (DUF4166)
KLOEOPPO_01147 0.0 yndJ S YndJ-like protein
KLOEOPPO_01149 8.6e-139 yndL S Replication protein
KLOEOPPO_01150 5.8e-74 yndM S Protein of unknown function (DUF2512)
KLOEOPPO_01151 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KLOEOPPO_01153 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KLOEOPPO_01154 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KLOEOPPO_01155 9.2e-113 yneB L resolvase
KLOEOPPO_01156 1.3e-32 ynzC S UPF0291 protein
KLOEOPPO_01157 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KLOEOPPO_01158 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
KLOEOPPO_01159 1.8e-28 yneF S UPF0154 protein
KLOEOPPO_01160 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
KLOEOPPO_01161 7.1e-127 ccdA O cytochrome c biogenesis protein
KLOEOPPO_01162 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KLOEOPPO_01163 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KLOEOPPO_01164 4.2e-74 yneK S Protein of unknown function (DUF2621)
KLOEOPPO_01165 4.1e-65 hspX O Spore coat protein
KLOEOPPO_01166 3.9e-19 sspP S Belongs to the SspP family
KLOEOPPO_01167 2.2e-14 sspO S Belongs to the SspO family
KLOEOPPO_01168 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KLOEOPPO_01169 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KLOEOPPO_01171 3.1e-08 sspN S Small acid-soluble spore protein N family
KLOEOPPO_01172 3.9e-35 tlp S Belongs to the Tlp family
KLOEOPPO_01173 1.2e-73 yneP S Thioesterase-like superfamily
KLOEOPPO_01174 1.3e-53 yneQ
KLOEOPPO_01175 4.1e-49 yneR S Belongs to the HesB IscA family
KLOEOPPO_01176 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KLOEOPPO_01177 6.6e-69 yccU S CoA-binding protein
KLOEOPPO_01178 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLOEOPPO_01179 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLOEOPPO_01180 2.3e-12
KLOEOPPO_01181 1.3e-57 ynfC
KLOEOPPO_01182 8.2e-252 agcS E Sodium alanine symporter
KLOEOPPO_01183 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KLOEOPPO_01185 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
KLOEOPPO_01186 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KLOEOPPO_01187 2.4e-80 yngA S membrane
KLOEOPPO_01188 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KLOEOPPO_01189 5.5e-104 yngC S membrane-associated protein
KLOEOPPO_01190 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
KLOEOPPO_01191 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KLOEOPPO_01192 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KLOEOPPO_01193 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KLOEOPPO_01194 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KLOEOPPO_01195 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KLOEOPPO_01196 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KLOEOPPO_01197 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KLOEOPPO_01198 1.8e-31 S Family of unknown function (DUF5367)
KLOEOPPO_01200 1.3e-306 yngK T Glycosyl hydrolase-like 10
KLOEOPPO_01201 2.8e-64 yngL S Protein of unknown function (DUF1360)
KLOEOPPO_01202 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KLOEOPPO_01203 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_01204 1.4e-95 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_01205 1.3e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KLOEOPPO_01206 1.8e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
KLOEOPPO_01207 7.4e-245 yoeA V MATE efflux family protein
KLOEOPPO_01208 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
KLOEOPPO_01210 2.2e-96 L Integrase
KLOEOPPO_01211 8.7e-34 yoeD G Helix-turn-helix domain
KLOEOPPO_01212 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KLOEOPPO_01213 6.3e-154 gltR1 K Transcriptional regulator
KLOEOPPO_01214 3e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KLOEOPPO_01215 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KLOEOPPO_01216 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KLOEOPPO_01217 7.8e-155 gltC K Transcriptional regulator
KLOEOPPO_01218 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLOEOPPO_01219 2.1e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLOEOPPO_01220 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KLOEOPPO_01221 2e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KLOEOPPO_01222 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
KLOEOPPO_01223 1.1e-130 yoxB
KLOEOPPO_01224 1.4e-87 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KLOEOPPO_01225 6.2e-235 yoaB EGP Major facilitator Superfamily
KLOEOPPO_01226 1.1e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KLOEOPPO_01227 1.3e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLOEOPPO_01228 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KLOEOPPO_01229 1.9e-33 yoaF
KLOEOPPO_01230 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
KLOEOPPO_01231 7e-14
KLOEOPPO_01232 1.5e-38 S Protein of unknown function (DUF4025)
KLOEOPPO_01233 2.2e-187 mcpU NT methyl-accepting chemotaxis protein
KLOEOPPO_01234 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KLOEOPPO_01235 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
KLOEOPPO_01236 2.3e-111 yoaK S Membrane
KLOEOPPO_01237 1.4e-195 pelB 4.2.2.10, 4.2.2.2 G Amb_all
KLOEOPPO_01238 4.6e-131 yoqW S Belongs to the SOS response-associated peptidase family
KLOEOPPO_01241 2.3e-231 oxdC 4.1.1.2 G Oxalate decarboxylase
KLOEOPPO_01243 3.9e-18 yoaP 3.1.3.18 K YoaP-like
KLOEOPPO_01245 4.3e-86
KLOEOPPO_01246 7.1e-172 yoaR V vancomycin resistance protein
KLOEOPPO_01247 7.3e-75 yoaS S Protein of unknown function (DUF2975)
KLOEOPPO_01248 4.4e-30 yozG K Transcriptional regulator
KLOEOPPO_01249 4.8e-148 yoaT S Protein of unknown function (DUF817)
KLOEOPPO_01250 8.6e-159 yoaU K LysR substrate binding domain
KLOEOPPO_01251 6e-160 yijE EG EamA-like transporter family
KLOEOPPO_01252 3.7e-78 yoaW
KLOEOPPO_01253 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KLOEOPPO_01254 6.7e-170 bla 3.5.2.6 V beta-lactamase
KLOEOPPO_01258 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
KLOEOPPO_01259 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
KLOEOPPO_01260 3e-37 S TM2 domain
KLOEOPPO_01261 5.7e-58 K Helix-turn-helix
KLOEOPPO_01263 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
KLOEOPPO_01264 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
KLOEOPPO_01265 1.8e-178 yobF
KLOEOPPO_01270 1.7e-207 S aspartate phosphatase
KLOEOPPO_01272 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLOEOPPO_01273 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLOEOPPO_01274 2.6e-38 S YolD-like protein
KLOEOPPO_01275 1.2e-49
KLOEOPPO_01276 0.0 K Psort location Cytoplasmic, score
KLOEOPPO_01277 2.7e-157 yobJ
KLOEOPPO_01278 3e-86 S SMI1-KNR4 cell-wall
KLOEOPPO_01279 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KLOEOPPO_01280 7.9e-105 yokH G SMI1 / KNR4 family
KLOEOPPO_01281 2.1e-279 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
KLOEOPPO_01282 0.0 yobO M Pectate lyase superfamily protein
KLOEOPPO_01283 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KLOEOPPO_01284 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
KLOEOPPO_01285 2.5e-143 yobR 2.3.1.1 J FR47-like protein
KLOEOPPO_01286 3e-99 yobS K Transcriptional regulator
KLOEOPPO_01287 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KLOEOPPO_01288 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
KLOEOPPO_01289 9e-178 yobV K WYL domain
KLOEOPPO_01290 2.5e-95 yobW
KLOEOPPO_01291 1e-51 czrA K transcriptional
KLOEOPPO_01292 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KLOEOPPO_01293 1.5e-92 yozB S membrane
KLOEOPPO_01294 2.2e-145
KLOEOPPO_01295 1.9e-94 yocC
KLOEOPPO_01296 6.9e-189 yocD 3.4.17.13 V peptidase S66
KLOEOPPO_01297 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KLOEOPPO_01298 3.2e-198 desK 2.7.13.3 T Histidine kinase
KLOEOPPO_01299 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLOEOPPO_01300 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
KLOEOPPO_01301 0.0 recQ 3.6.4.12 L DNA helicase
KLOEOPPO_01302 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KLOEOPPO_01303 3.3e-83 dksA T general stress protein
KLOEOPPO_01304 6.4e-54 yocL
KLOEOPPO_01305 6.6e-34
KLOEOPPO_01306 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
KLOEOPPO_01307 1.1e-40 yozN
KLOEOPPO_01308 1.9e-36 yocN
KLOEOPPO_01309 4.2e-56 yozO S Bacterial PH domain
KLOEOPPO_01310 2.7e-31 yozC
KLOEOPPO_01311 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KLOEOPPO_01312 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KLOEOPPO_01313 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
KLOEOPPO_01314 9.9e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KLOEOPPO_01315 8.6e-168 yocS S -transporter
KLOEOPPO_01316 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KLOEOPPO_01317 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KLOEOPPO_01318 0.0 yojO P Von Willebrand factor
KLOEOPPO_01319 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
KLOEOPPO_01320 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KLOEOPPO_01321 2.5e-196 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KLOEOPPO_01322 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KLOEOPPO_01323 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KLOEOPPO_01325 4.2e-245 norM V Multidrug efflux pump
KLOEOPPO_01326 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KLOEOPPO_01327 2.1e-125 yojG S deacetylase
KLOEOPPO_01328 2.2e-60 yojF S Protein of unknown function (DUF1806)
KLOEOPPO_01329 1.5e-43
KLOEOPPO_01330 6.6e-162 rarD S -transporter
KLOEOPPO_01331 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
KLOEOPPO_01332 3.4e-09
KLOEOPPO_01333 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
KLOEOPPO_01334 3.8e-66 yodA S tautomerase
KLOEOPPO_01335 1.7e-57 yodB K transcriptional
KLOEOPPO_01336 4.8e-108 yodC C nitroreductase
KLOEOPPO_01337 3.8e-113 mhqD S Carboxylesterase
KLOEOPPO_01338 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
KLOEOPPO_01339 6.2e-28 S Protein of unknown function (DUF3311)
KLOEOPPO_01340 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLOEOPPO_01341 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KLOEOPPO_01342 1.1e-127 yodH Q Methyltransferase
KLOEOPPO_01343 5.2e-24 yodI
KLOEOPPO_01344 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KLOEOPPO_01345 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KLOEOPPO_01346 5.3e-09
KLOEOPPO_01347 3.6e-54 yodL S YodL-like
KLOEOPPO_01348 3.5e-106 yodM 3.6.1.27 I Acid phosphatase homologues
KLOEOPPO_01349 2.8e-24 yozD S YozD-like protein
KLOEOPPO_01351 6e-123 yodN
KLOEOPPO_01352 1.4e-36 yozE S Belongs to the UPF0346 family
KLOEOPPO_01353 6.4e-47 yokU S YokU-like protein, putative antitoxin
KLOEOPPO_01354 5.1e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
KLOEOPPO_01355 6.7e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KLOEOPPO_01356 7.9e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
KLOEOPPO_01357 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KLOEOPPO_01358 3.8e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KLOEOPPO_01359 5.2e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KLOEOPPO_01361 1.8e-144 yiiD K acetyltransferase
KLOEOPPO_01362 9.4e-255 cgeD M maturation of the outermost layer of the spore
KLOEOPPO_01363 3.5e-38 cgeC
KLOEOPPO_01364 1.5e-65 cgeA
KLOEOPPO_01365 6.3e-187 cgeB S Spore maturation protein
KLOEOPPO_01366 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KLOEOPPO_01367 7.4e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
KLOEOPPO_01368 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KLOEOPPO_01369 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLOEOPPO_01370 1.6e-70 ypoP K transcriptional
KLOEOPPO_01371 1.4e-221 mepA V MATE efflux family protein
KLOEOPPO_01372 5.5e-29 ypmT S Uncharacterized ympT
KLOEOPPO_01373 5e-99 ypmS S protein conserved in bacteria
KLOEOPPO_01374 4.8e-137 ypmR E GDSL-like Lipase/Acylhydrolase
KLOEOPPO_01375 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KLOEOPPO_01376 3.1e-40 ypmP S Protein of unknown function (DUF2535)
KLOEOPPO_01377 1.1e-242 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KLOEOPPO_01378 1.6e-185 pspF K Transcriptional regulator
KLOEOPPO_01379 4.2e-110 hlyIII S protein, Hemolysin III
KLOEOPPO_01380 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KLOEOPPO_01381 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KLOEOPPO_01382 7.6e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLOEOPPO_01383 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KLOEOPPO_01384 8.6e-113 ypjP S YpjP-like protein
KLOEOPPO_01385 1.6e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KLOEOPPO_01386 1.7e-75 yphP S Belongs to the UPF0403 family
KLOEOPPO_01387 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KLOEOPPO_01388 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
KLOEOPPO_01389 6e-106 ypgQ S phosphohydrolase
KLOEOPPO_01390 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KLOEOPPO_01391 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KLOEOPPO_01392 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KLOEOPPO_01393 7.9e-31 cspD K Cold-shock protein
KLOEOPPO_01394 3.8e-16 degR
KLOEOPPO_01395 8.1e-31 S Protein of unknown function (DUF2564)
KLOEOPPO_01396 3e-29 ypeQ S Zinc-finger
KLOEOPPO_01397 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KLOEOPPO_01398 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KLOEOPPO_01399 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
KLOEOPPO_01401 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
KLOEOPPO_01402 2e-07
KLOEOPPO_01403 1e-38 ypbS S Protein of unknown function (DUF2533)
KLOEOPPO_01404 0.0 ypbR S Dynamin family
KLOEOPPO_01405 5.1e-87 ypbQ S protein conserved in bacteria
KLOEOPPO_01406 1.5e-205 bcsA Q Naringenin-chalcone synthase
KLOEOPPO_01407 1.5e-226 pbuX F xanthine
KLOEOPPO_01408 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KLOEOPPO_01409 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KLOEOPPO_01410 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KLOEOPPO_01411 2.7e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KLOEOPPO_01412 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KLOEOPPO_01413 4.1e-184 ptxS K transcriptional
KLOEOPPO_01414 2e-157 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KLOEOPPO_01415 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_01416 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KLOEOPPO_01418 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KLOEOPPO_01419 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KLOEOPPO_01420 3.7e-91 ypsA S Belongs to the UPF0398 family
KLOEOPPO_01421 5.6e-236 yprB L RNase_H superfamily
KLOEOPPO_01422 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KLOEOPPO_01423 5.5e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KLOEOPPO_01424 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
KLOEOPPO_01425 1.2e-48 yppG S YppG-like protein
KLOEOPPO_01427 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
KLOEOPPO_01430 2.6e-188 yppC S Protein of unknown function (DUF2515)
KLOEOPPO_01431 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KLOEOPPO_01432 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
KLOEOPPO_01433 4.7e-93 ypoC
KLOEOPPO_01434 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KLOEOPPO_01435 5.7e-129 dnaD L DNA replication protein DnaD
KLOEOPPO_01436 1.3e-251 asnS 6.1.1.22 J asparaginyl-tRNA
KLOEOPPO_01437 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KLOEOPPO_01438 3.4e-80 ypmB S protein conserved in bacteria
KLOEOPPO_01439 6.7e-23 ypmA S Protein of unknown function (DUF4264)
KLOEOPPO_01440 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KLOEOPPO_01441 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KLOEOPPO_01442 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KLOEOPPO_01443 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KLOEOPPO_01444 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KLOEOPPO_01445 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KLOEOPPO_01446 1.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KLOEOPPO_01447 6.9e-130 bshB1 S proteins, LmbE homologs
KLOEOPPO_01448 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KLOEOPPO_01449 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KLOEOPPO_01450 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KLOEOPPO_01451 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KLOEOPPO_01452 6.1e-143 ypjB S sporulation protein
KLOEOPPO_01453 2e-98 ypjA S membrane
KLOEOPPO_01454 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KLOEOPPO_01455 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KLOEOPPO_01456 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KLOEOPPO_01457 8.5e-78 ypiF S Protein of unknown function (DUF2487)
KLOEOPPO_01458 2.8e-99 ypiB S Belongs to the UPF0302 family
KLOEOPPO_01459 4.1e-234 S COG0457 FOG TPR repeat
KLOEOPPO_01460 7.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KLOEOPPO_01461 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KLOEOPPO_01462 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KLOEOPPO_01463 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KLOEOPPO_01464 9.9e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KLOEOPPO_01465 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KLOEOPPO_01466 1.5e-111 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KLOEOPPO_01467 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KLOEOPPO_01468 5.6e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KLOEOPPO_01469 3e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KLOEOPPO_01470 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KLOEOPPO_01471 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KLOEOPPO_01472 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KLOEOPPO_01473 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KLOEOPPO_01474 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLOEOPPO_01475 3.3e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KLOEOPPO_01476 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KLOEOPPO_01477 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KLOEOPPO_01478 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
KLOEOPPO_01479 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KLOEOPPO_01480 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KLOEOPPO_01481 2.1e-137 yphF
KLOEOPPO_01482 1.6e-18 yphE S Protein of unknown function (DUF2768)
KLOEOPPO_01483 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KLOEOPPO_01484 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KLOEOPPO_01485 1.6e-28 ypzH
KLOEOPPO_01486 2.5e-161 seaA S YIEGIA protein
KLOEOPPO_01487 1.3e-102 yphA
KLOEOPPO_01488 1e-07 S YpzI-like protein
KLOEOPPO_01489 2.6e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KLOEOPPO_01490 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
KLOEOPPO_01491 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KLOEOPPO_01492 1.8e-23 S Family of unknown function (DUF5359)
KLOEOPPO_01493 5.9e-112 ypfA M Flagellar protein YcgR
KLOEOPPO_01494 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KLOEOPPO_01495 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KLOEOPPO_01496 1.5e-118 prsW S Involved in the degradation of specific anti-sigma factors
KLOEOPPO_01497 1.4e-173 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KLOEOPPO_01498 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KLOEOPPO_01499 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KLOEOPPO_01500 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
KLOEOPPO_01501 2.8e-81 ypbF S Protein of unknown function (DUF2663)
KLOEOPPO_01502 4.6e-81 ypbE M Lysin motif
KLOEOPPO_01503 2.2e-100 ypbD S metal-dependent membrane protease
KLOEOPPO_01504 3.2e-286 recQ 3.6.4.12 L DNA helicase
KLOEOPPO_01505 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
KLOEOPPO_01506 4.7e-41 fer C Ferredoxin
KLOEOPPO_01507 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KLOEOPPO_01508 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLOEOPPO_01509 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KLOEOPPO_01510 6.8e-201 rsiX
KLOEOPPO_01511 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KLOEOPPO_01512 0.0 resE 2.7.13.3 T Histidine kinase
KLOEOPPO_01513 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_01514 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KLOEOPPO_01515 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KLOEOPPO_01516 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KLOEOPPO_01517 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLOEOPPO_01518 1.9e-87 spmB S Spore maturation protein
KLOEOPPO_01519 3.5e-103 spmA S Spore maturation protein
KLOEOPPO_01520 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KLOEOPPO_01521 4e-98 ypuI S Protein of unknown function (DUF3907)
KLOEOPPO_01522 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KLOEOPPO_01523 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KLOEOPPO_01524 2.1e-91 ypuF S Domain of unknown function (DUF309)
KLOEOPPO_01525 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLOEOPPO_01526 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KLOEOPPO_01527 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KLOEOPPO_01528 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
KLOEOPPO_01529 4.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KLOEOPPO_01530 6.6e-54 ypuD
KLOEOPPO_01531 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KLOEOPPO_01532 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
KLOEOPPO_01533 1.5e-17 S SNARE associated Golgi protein
KLOEOPPO_01536 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLOEOPPO_01537 1.3e-149 ypuA S Secreted protein
KLOEOPPO_01538 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KLOEOPPO_01539 1.4e-273 spoVAF EG Stage V sporulation protein AF
KLOEOPPO_01540 1.4e-110 spoVAEA S stage V sporulation protein
KLOEOPPO_01541 2.2e-57 spoVAEB S stage V sporulation protein
KLOEOPPO_01542 9e-192 spoVAD I Stage V sporulation protein AD
KLOEOPPO_01543 2.3e-78 spoVAC S stage V sporulation protein AC
KLOEOPPO_01544 1e-67 spoVAB S Stage V sporulation protein AB
KLOEOPPO_01545 9.6e-112 spoVAA S Stage V sporulation protein AA
KLOEOPPO_01546 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KLOEOPPO_01547 8.7e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KLOEOPPO_01548 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KLOEOPPO_01549 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KLOEOPPO_01550 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KLOEOPPO_01551 1.1e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KLOEOPPO_01552 4.4e-166 xerD L recombinase XerD
KLOEOPPO_01553 1.4e-36 S Protein of unknown function (DUF4227)
KLOEOPPO_01554 2.4e-80 fur P Belongs to the Fur family
KLOEOPPO_01555 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KLOEOPPO_01556 2.2e-31 yqkK
KLOEOPPO_01557 5.5e-242 mleA 1.1.1.38 C malic enzyme
KLOEOPPO_01558 3.1e-235 mleN C Na H antiporter
KLOEOPPO_01559 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KLOEOPPO_01560 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase
KLOEOPPO_01561 4.5e-58 ansR K Transcriptional regulator
KLOEOPPO_01562 1.4e-220 yqxK 3.6.4.12 L DNA helicase
KLOEOPPO_01563 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KLOEOPPO_01565 4.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KLOEOPPO_01566 3.1e-12 yqkE S Protein of unknown function (DUF3886)
KLOEOPPO_01567 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KLOEOPPO_01568 9.4e-39 yqkC S Protein of unknown function (DUF2552)
KLOEOPPO_01569 2.8e-54 yqkB S Belongs to the HesB IscA family
KLOEOPPO_01570 7.5e-194 yqkA K GrpB protein
KLOEOPPO_01571 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KLOEOPPO_01572 1.8e-86 yqjY K acetyltransferase
KLOEOPPO_01573 2.2e-49 S YolD-like protein
KLOEOPPO_01574 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLOEOPPO_01576 6.1e-222 yqjV G Major Facilitator Superfamily
KLOEOPPO_01578 2.1e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLOEOPPO_01579 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
KLOEOPPO_01580 6e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KLOEOPPO_01581 1e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KLOEOPPO_01582 1.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KLOEOPPO_01583 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLOEOPPO_01584 0.0 rocB E arginine degradation protein
KLOEOPPO_01585 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KLOEOPPO_01586 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KLOEOPPO_01587 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KLOEOPPO_01588 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KLOEOPPO_01589 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KLOEOPPO_01590 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLOEOPPO_01591 4.5e-24 yqzJ
KLOEOPPO_01592 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLOEOPPO_01593 8.9e-141 yqjF S Uncharacterized conserved protein (COG2071)
KLOEOPPO_01594 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KLOEOPPO_01595 1.8e-289 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KLOEOPPO_01596 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KLOEOPPO_01598 1.8e-98 yqjB S protein conserved in bacteria
KLOEOPPO_01599 1.2e-174 yqjA S Putative aromatic acid exporter C-terminal domain
KLOEOPPO_01600 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KLOEOPPO_01601 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
KLOEOPPO_01602 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
KLOEOPPO_01603 9.3e-77 yqiW S Belongs to the UPF0403 family
KLOEOPPO_01604 1.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KLOEOPPO_01605 3.9e-207 norA EGP Major facilitator Superfamily
KLOEOPPO_01606 2.6e-152 bmrR K helix_turn_helix, mercury resistance
KLOEOPPO_01607 2.2e-219 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KLOEOPPO_01608 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KLOEOPPO_01609 7.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KLOEOPPO_01610 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KLOEOPPO_01611 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
KLOEOPPO_01612 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KLOEOPPO_01613 3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KLOEOPPO_01614 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KLOEOPPO_01615 4e-34 yqzF S Protein of unknown function (DUF2627)
KLOEOPPO_01616 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KLOEOPPO_01617 2.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KLOEOPPO_01618 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KLOEOPPO_01619 1.8e-212 mmgC I acyl-CoA dehydrogenase
KLOEOPPO_01620 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
KLOEOPPO_01621 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
KLOEOPPO_01622 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KLOEOPPO_01623 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KLOEOPPO_01624 5.9e-27
KLOEOPPO_01625 1.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KLOEOPPO_01627 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KLOEOPPO_01628 1.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
KLOEOPPO_01629 6.5e-307 recN L May be involved in recombinational repair of damaged DNA
KLOEOPPO_01630 1.7e-78 argR K Regulates arginine biosynthesis genes
KLOEOPPO_01631 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KLOEOPPO_01632 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KLOEOPPO_01633 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLOEOPPO_01634 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLOEOPPO_01635 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLOEOPPO_01636 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KLOEOPPO_01637 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLOEOPPO_01638 2.1e-67 yqhY S protein conserved in bacteria
KLOEOPPO_01639 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KLOEOPPO_01640 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KLOEOPPO_01641 9.9e-91 spoIIIAH S SpoIIIAH-like protein
KLOEOPPO_01642 2.2e-109 spoIIIAG S stage III sporulation protein AG
KLOEOPPO_01643 9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KLOEOPPO_01644 2.9e-197 spoIIIAE S stage III sporulation protein AE
KLOEOPPO_01645 2.3e-58 spoIIIAD S Stage III sporulation protein AD
KLOEOPPO_01646 7.6e-29 spoIIIAC S stage III sporulation protein AC
KLOEOPPO_01647 3.2e-84 spoIIIAB S Stage III sporulation protein
KLOEOPPO_01648 6.8e-170 spoIIIAA S stage III sporulation protein AA
KLOEOPPO_01649 7.9e-37 yqhV S Protein of unknown function (DUF2619)
KLOEOPPO_01650 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLOEOPPO_01651 9.8e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KLOEOPPO_01652 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KLOEOPPO_01653 2.3e-93 yqhR S Conserved membrane protein YqhR
KLOEOPPO_01654 8e-174 yqhQ S Protein of unknown function (DUF1385)
KLOEOPPO_01655 2.2e-61 yqhP
KLOEOPPO_01656 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
KLOEOPPO_01657 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KLOEOPPO_01658 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KLOEOPPO_01659 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
KLOEOPPO_01660 2.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KLOEOPPO_01661 1.1e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KLOEOPPO_01662 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KLOEOPPO_01663 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KLOEOPPO_01664 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
KLOEOPPO_01665 1.2e-24 sinI S Anti-repressor SinI
KLOEOPPO_01666 1e-54 sinR K transcriptional
KLOEOPPO_01667 2.5e-141 tasA S Cell division protein FtsN
KLOEOPPO_01668 1.9e-58 sipW 3.4.21.89 U Signal peptidase
KLOEOPPO_01669 1.3e-113 yqxM
KLOEOPPO_01670 7.3e-54 yqzG S Protein of unknown function (DUF3889)
KLOEOPPO_01671 4.4e-25 yqzE S YqzE-like protein
KLOEOPPO_01672 1.8e-44 S ComG operon protein 7
KLOEOPPO_01673 3e-44 comGF U Putative Competence protein ComGF
KLOEOPPO_01674 1.1e-59 comGE
KLOEOPPO_01675 7.7e-68 gspH NU protein transport across the cell outer membrane
KLOEOPPO_01676 5.2e-47 comGC U Required for transformation and DNA binding
KLOEOPPO_01677 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
KLOEOPPO_01678 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KLOEOPPO_01681 7.2e-175 corA P Mg2 transporter protein
KLOEOPPO_01682 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KLOEOPPO_01683 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KLOEOPPO_01685 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
KLOEOPPO_01686 1.8e-37 yqgY S Protein of unknown function (DUF2626)
KLOEOPPO_01687 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KLOEOPPO_01688 8.9e-23 yqgW S Protein of unknown function (DUF2759)
KLOEOPPO_01689 6.9e-50 yqgV S Thiamine-binding protein
KLOEOPPO_01690 2.7e-199 yqgU
KLOEOPPO_01691 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KLOEOPPO_01692 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KLOEOPPO_01693 5.2e-181 glcK 2.7.1.2 G Glucokinase
KLOEOPPO_01694 3.1e-33 yqgQ S Protein conserved in bacteria
KLOEOPPO_01695 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KLOEOPPO_01696 2.5e-09 yqgO
KLOEOPPO_01697 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KLOEOPPO_01698 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KLOEOPPO_01699 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
KLOEOPPO_01701 9.2e-51 yqzD
KLOEOPPO_01702 4.1e-75 yqzC S YceG-like family
KLOEOPPO_01703 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLOEOPPO_01704 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLOEOPPO_01705 4.4e-158 pstA P Phosphate transport system permease
KLOEOPPO_01706 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
KLOEOPPO_01707 2e-150 pstS P Phosphate
KLOEOPPO_01708 0.0 pbpA 3.4.16.4 M penicillin-binding protein
KLOEOPPO_01709 2.5e-231 yqgE EGP Major facilitator superfamily
KLOEOPPO_01710 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KLOEOPPO_01711 4e-73 yqgC S protein conserved in bacteria
KLOEOPPO_01712 8.5e-134 yqgB S Protein of unknown function (DUF1189)
KLOEOPPO_01713 2.2e-75 yqgA
KLOEOPPO_01714 5.2e-47 yqfZ M LysM domain
KLOEOPPO_01715 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KLOEOPPO_01716 2.8e-61 yqfX S membrane
KLOEOPPO_01717 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KLOEOPPO_01718 4.2e-77 zur P Belongs to the Fur family
KLOEOPPO_01719 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KLOEOPPO_01720 2.1e-36 yqfT S Protein of unknown function (DUF2624)
KLOEOPPO_01721 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KLOEOPPO_01722 2.9e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KLOEOPPO_01723 3.6e-12 yqfQ S YqfQ-like protein
KLOEOPPO_01724 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KLOEOPPO_01725 1.2e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KLOEOPPO_01726 1.4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
KLOEOPPO_01727 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
KLOEOPPO_01728 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KLOEOPPO_01729 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KLOEOPPO_01730 4.5e-88 yaiI S Belongs to the UPF0178 family
KLOEOPPO_01731 8.4e-148 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KLOEOPPO_01732 4.5e-112 ccpN K CBS domain
KLOEOPPO_01733 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KLOEOPPO_01734 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KLOEOPPO_01735 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
KLOEOPPO_01736 8.4e-19 S YqzL-like protein
KLOEOPPO_01737 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KLOEOPPO_01738 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KLOEOPPO_01739 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KLOEOPPO_01740 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KLOEOPPO_01741 0.0 yqfF S membrane-associated HD superfamily hydrolase
KLOEOPPO_01743 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
KLOEOPPO_01744 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KLOEOPPO_01745 2.7e-45 yqfC S sporulation protein YqfC
KLOEOPPO_01746 3.7e-22 yqfB
KLOEOPPO_01747 4.3e-122 yqfA S UPF0365 protein
KLOEOPPO_01748 1e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KLOEOPPO_01749 2.5e-61 yqeY S Yqey-like protein
KLOEOPPO_01750 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KLOEOPPO_01751 8.2e-158 yqeW P COG1283 Na phosphate symporter
KLOEOPPO_01752 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KLOEOPPO_01753 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KLOEOPPO_01754 6e-174 prmA J Methylates ribosomal protein L11
KLOEOPPO_01755 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KLOEOPPO_01756 0.0 dnaK O Heat shock 70 kDa protein
KLOEOPPO_01757 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KLOEOPPO_01758 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KLOEOPPO_01759 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KLOEOPPO_01760 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KLOEOPPO_01761 1e-54 yqxA S Protein of unknown function (DUF3679)
KLOEOPPO_01762 6.9e-223 spoIIP M stage II sporulation protein P
KLOEOPPO_01763 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KLOEOPPO_01764 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
KLOEOPPO_01765 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
KLOEOPPO_01766 4.1e-15 S YqzM-like protein
KLOEOPPO_01767 0.0 comEC S Competence protein ComEC
KLOEOPPO_01768 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
KLOEOPPO_01769 4.3e-104 wza L COG1555 DNA uptake protein and related DNA-binding proteins
KLOEOPPO_01770 4.6e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLOEOPPO_01771 2.9e-139 yqeM Q Methyltransferase
KLOEOPPO_01772 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KLOEOPPO_01773 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KLOEOPPO_01774 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KLOEOPPO_01775 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KLOEOPPO_01776 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KLOEOPPO_01777 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KLOEOPPO_01778 5.3e-95 yqeG S hydrolase of the HAD superfamily
KLOEOPPO_01780 1.8e-141 yqeF E GDSL-like Lipase/Acylhydrolase
KLOEOPPO_01781 7e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KLOEOPPO_01782 1.2e-104 yqeD S SNARE associated Golgi protein
KLOEOPPO_01783 5.2e-19 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KLOEOPPO_01784 4.2e-133 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KLOEOPPO_01785 2.3e-133 yqeB
KLOEOPPO_01786 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
KLOEOPPO_01787 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KLOEOPPO_01788 1.4e-281 cisA2 L Recombinase
KLOEOPPO_01789 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KLOEOPPO_01790 8.7e-182 arsB 1.20.4.1 P Arsenic resistance protein
KLOEOPPO_01791 3.7e-65 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLOEOPPO_01792 2.1e-54 arsR K ArsR family transcriptional regulator
KLOEOPPO_01793 4.8e-145 yqcI S YqcI/YcgG family
KLOEOPPO_01794 1.6e-96 S Tetratricopeptide repeat
KLOEOPPO_01797 3.8e-277 A Pre-toxin TG
KLOEOPPO_01798 1.1e-104 S Suppressor of fused protein (SUFU)
KLOEOPPO_01800 5e-60
KLOEOPPO_01802 4.5e-141 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KLOEOPPO_01803 1.9e-66 S Bacteriophage holin family
KLOEOPPO_01804 1.4e-159 xepA
KLOEOPPO_01805 1.3e-23
KLOEOPPO_01806 4.1e-56 xkdW S XkdW protein
KLOEOPPO_01807 5.9e-221
KLOEOPPO_01808 9e-38
KLOEOPPO_01809 8.2e-97 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KLOEOPPO_01810 2.2e-185 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KLOEOPPO_01811 5e-67 xkdS S Protein of unknown function (DUF2634)
KLOEOPPO_01812 1.1e-35 xkdR S Protein of unknown function (DUF2577)
KLOEOPPO_01813 5.1e-176 yqbQ 3.2.1.96 G NLP P60 protein
KLOEOPPO_01814 1.7e-112 xkdP S Lysin motif
KLOEOPPO_01815 0.0 xkdO L Transglycosylase SLT domain
KLOEOPPO_01816 6.2e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
KLOEOPPO_01818 3.6e-76 xkdM S Phage tail tube protein
KLOEOPPO_01819 5.5e-256 xkdK S Phage tail sheath C-terminal domain
KLOEOPPO_01820 3.2e-26
KLOEOPPO_01821 1.4e-77
KLOEOPPO_01822 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
KLOEOPPO_01823 6.7e-65 yqbH S Domain of unknown function (DUF3599)
KLOEOPPO_01824 2.1e-67 S Protein of unknown function (DUF3199)
KLOEOPPO_01825 3.6e-51 S YqbF, hypothetical protein domain
KLOEOPPO_01826 1.9e-167 xkdG S Phage capsid family
KLOEOPPO_01827 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KLOEOPPO_01828 2e-115
KLOEOPPO_01829 5.7e-169 S Phage Mu protein F like protein
KLOEOPPO_01830 1.8e-289 yqbA S portal protein
KLOEOPPO_01831 2.1e-246 S phage terminase, large subunit
KLOEOPPO_01832 1.5e-95 yqaS L DNA packaging
KLOEOPPO_01834 3.7e-76 L Transposase
KLOEOPPO_01835 1.5e-06
KLOEOPPO_01836 2.4e-30 yqaO S Phage-like element PBSX protein XtrA
KLOEOPPO_01837 5.7e-71 rusA L Endodeoxyribonuclease RusA
KLOEOPPO_01839 2.2e-162 xkdC L IstB-like ATP binding protein
KLOEOPPO_01840 9.8e-121 3.1.3.16 L DnaD domain protein
KLOEOPPO_01841 1.2e-149 recT L RecT family
KLOEOPPO_01842 4.9e-163 yqaJ L YqaJ-like viral recombinase domain
KLOEOPPO_01846 1.7e-102
KLOEOPPO_01848 2e-17 K Helix-turn-helix XRE-family like proteins
KLOEOPPO_01849 1.1e-32 K sequence-specific DNA binding
KLOEOPPO_01850 7.2e-11 S Protein of unknown function (DUF4064)
KLOEOPPO_01851 3.9e-101 adk 2.7.4.3 F adenylate kinase activity
KLOEOPPO_01852 9.9e-89 yqaB E IrrE N-terminal-like domain
KLOEOPPO_01854 2.3e-27
KLOEOPPO_01855 7.3e-17
KLOEOPPO_01856 2.8e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KLOEOPPO_01857 2e-68 psiE S Protein PsiE homolog
KLOEOPPO_01858 4.5e-236 yrkQ T Histidine kinase
KLOEOPPO_01859 1.1e-127 T Transcriptional regulator
KLOEOPPO_01860 8.2e-224 yrkO P Protein of unknown function (DUF418)
KLOEOPPO_01861 4.3e-103 yrkN K Acetyltransferase (GNAT) family
KLOEOPPO_01862 1.5e-97 ywrO S Flavodoxin-like fold
KLOEOPPO_01863 2.8e-79 S Protein of unknown function with HXXEE motif
KLOEOPPO_01864 1.2e-111 yrkJ S membrane transporter protein
KLOEOPPO_01865 2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
KLOEOPPO_01866 4.3e-203 yrkH P Rhodanese Homology Domain
KLOEOPPO_01867 5.5e-17 perX S DsrE/DsrF-like family
KLOEOPPO_01868 5.4e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
KLOEOPPO_01869 2.8e-82 yrkE O DsrE/DsrF/DrsH-like family
KLOEOPPO_01870 7.8e-39 yrkD S protein conserved in bacteria
KLOEOPPO_01871 1.3e-107 yrkC G Cupin domain
KLOEOPPO_01872 3.1e-150 bltR K helix_turn_helix, mercury resistance
KLOEOPPO_01873 8.7e-210 blt EGP Major facilitator Superfamily
KLOEOPPO_01874 5.9e-82 bltD 2.3.1.57 K FR47-like protein
KLOEOPPO_01875 7.9e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KLOEOPPO_01876 3.9e-16 S YrzO-like protein
KLOEOPPO_01877 2.7e-169 yrdR EG EamA-like transporter family
KLOEOPPO_01878 9.5e-158 yrdQ K Transcriptional regulator
KLOEOPPO_01879 3.5e-199 trkA P Oxidoreductase
KLOEOPPO_01880 3.5e-145 czcD P COG1230 Co Zn Cd efflux system component
KLOEOPPO_01881 1.7e-66 yodA S tautomerase
KLOEOPPO_01882 5e-162 gltR K LysR substrate binding domain
KLOEOPPO_01883 3e-227 brnQ E Component of the transport system for branched-chain amino acids
KLOEOPPO_01884 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
KLOEOPPO_01885 2.8e-137 azlC E AzlC protein
KLOEOPPO_01886 6.3e-79 bkdR K helix_turn_helix ASNC type
KLOEOPPO_01887 1.2e-15 yrdF K ribonuclease inhibitor
KLOEOPPO_01888 5.6e-228 cypA C Cytochrome P450
KLOEOPPO_01889 1.1e-23 K Acetyltransferase (GNAT) family
KLOEOPPO_01890 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
KLOEOPPO_01891 6.4e-90 yrdA S DinB family
KLOEOPPO_01892 1.5e-163 aadK G Streptomycin adenylyltransferase
KLOEOPPO_01893 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KLOEOPPO_01895 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KLOEOPPO_01896 1.6e-123 yrpD S Domain of unknown function, YrpD
KLOEOPPO_01897 1.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
KLOEOPPO_01899 2.8e-209 rbtT P Major Facilitator Superfamily
KLOEOPPO_01900 4.3e-114 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_01901 7e-154 2.2.1.1 G Transketolase, pyrimidine binding domain
KLOEOPPO_01902 6.4e-135 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
KLOEOPPO_01903 5.6e-98 flr S Flavin reductase like domain
KLOEOPPO_01904 7.2e-118 bmrR K helix_turn_helix, mercury resistance
KLOEOPPO_01905 2.2e-47 yjbR S YjbR
KLOEOPPO_01906 1.3e-113 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KLOEOPPO_01907 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
KLOEOPPO_01908 3.8e-187 yrpG C Aldo/keto reductase family
KLOEOPPO_01909 4e-224 yraO C Citrate transporter
KLOEOPPO_01910 3.7e-162 yraN K Transcriptional regulator
KLOEOPPO_01911 6.5e-204 yraM S PrpF protein
KLOEOPPO_01912 1.5e-149 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KLOEOPPO_01913 2.1e-39 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLOEOPPO_01914 8.4e-148 S Alpha beta hydrolase
KLOEOPPO_01915 1.7e-60 T sh3 domain protein
KLOEOPPO_01916 2.4e-61 T sh3 domain protein
KLOEOPPO_01918 3.8e-66 E Glyoxalase-like domain
KLOEOPPO_01919 1.5e-36 yraG
KLOEOPPO_01920 6.4e-63 yraF M Spore coat protein
KLOEOPPO_01921 3.8e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KLOEOPPO_01922 7.5e-26 yraE
KLOEOPPO_01923 1.1e-49 yraD M Spore coat protein
KLOEOPPO_01924 1.6e-46 yraB K helix_turn_helix, mercury resistance
KLOEOPPO_01925 1.6e-28 yphJ 4.1.1.44 S peroxiredoxin activity
KLOEOPPO_01926 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
KLOEOPPO_01927 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
KLOEOPPO_01928 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KLOEOPPO_01929 9.7e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KLOEOPPO_01930 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KLOEOPPO_01931 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
KLOEOPPO_01932 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
KLOEOPPO_01933 0.0 levR K PTS system fructose IIA component
KLOEOPPO_01934 4.3e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KLOEOPPO_01935 1.1e-105 yrhP E LysE type translocator
KLOEOPPO_01936 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
KLOEOPPO_01937 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KLOEOPPO_01938 3.8e-151 rsiV S Protein of unknown function (DUF3298)
KLOEOPPO_01939 0.0 yrhL I Acyltransferase family
KLOEOPPO_01940 4.3e-46 yrhK S YrhK-like protein
KLOEOPPO_01941 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KLOEOPPO_01942 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KLOEOPPO_01943 4.5e-97 yrhH Q methyltransferase
KLOEOPPO_01946 1.8e-142 focA P Formate nitrite
KLOEOPPO_01948 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
KLOEOPPO_01949 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KLOEOPPO_01950 1.2e-77 yrhD S Protein of unknown function (DUF1641)
KLOEOPPO_01951 4.6e-35 yrhC S YrhC-like protein
KLOEOPPO_01952 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KLOEOPPO_01953 6.1e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KLOEOPPO_01954 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KLOEOPPO_01955 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KLOEOPPO_01956 1e-25 yrzA S Protein of unknown function (DUF2536)
KLOEOPPO_01957 4.2e-63 yrrS S Protein of unknown function (DUF1510)
KLOEOPPO_01958 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KLOEOPPO_01959 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLOEOPPO_01960 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KLOEOPPO_01961 2.7e-246 yegQ O COG0826 Collagenase and related proteases
KLOEOPPO_01962 7.8e-174 yegQ O Peptidase U32
KLOEOPPO_01963 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
KLOEOPPO_01964 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KLOEOPPO_01965 1.2e-45 yrzB S Belongs to the UPF0473 family
KLOEOPPO_01966 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KLOEOPPO_01967 1.7e-41 yrzL S Belongs to the UPF0297 family
KLOEOPPO_01968 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLOEOPPO_01969 7.8e-170 yrrI S AI-2E family transporter
KLOEOPPO_01970 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KLOEOPPO_01971 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
KLOEOPPO_01972 1.8e-108 gluC P ABC transporter
KLOEOPPO_01973 7.6e-107 glnP P ABC transporter
KLOEOPPO_01974 8e-08 S Protein of unknown function (DUF3918)
KLOEOPPO_01975 9.8e-31 yrzR
KLOEOPPO_01976 3.5e-82 yrrD S protein conserved in bacteria
KLOEOPPO_01977 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KLOEOPPO_01978 1.4e-15 S COG0457 FOG TPR repeat
KLOEOPPO_01979 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KLOEOPPO_01980 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
KLOEOPPO_01981 1.2e-70 cymR K Transcriptional regulator
KLOEOPPO_01982 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KLOEOPPO_01983 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KLOEOPPO_01984 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KLOEOPPO_01985 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KLOEOPPO_01987 7e-260 lytH 3.5.1.28 M COG3103 SH3 domain protein
KLOEOPPO_01988 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KLOEOPPO_01989 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KLOEOPPO_01990 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KLOEOPPO_01991 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KLOEOPPO_01992 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
KLOEOPPO_01993 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KLOEOPPO_01994 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KLOEOPPO_01995 1.6e-48 yrzD S Post-transcriptional regulator
KLOEOPPO_01996 8.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KLOEOPPO_01997 1.1e-113 yrbG S membrane
KLOEOPPO_01998 1.2e-74 yrzE S Protein of unknown function (DUF3792)
KLOEOPPO_01999 1.1e-38 yajC U Preprotein translocase subunit YajC
KLOEOPPO_02000 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KLOEOPPO_02001 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KLOEOPPO_02002 1e-17 yrzS S Protein of unknown function (DUF2905)
KLOEOPPO_02003 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KLOEOPPO_02004 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KLOEOPPO_02005 4.8e-93 bofC S BofC C-terminal domain
KLOEOPPO_02006 5.3e-253 csbX EGP Major facilitator Superfamily
KLOEOPPO_02007 1.4e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
KLOEOPPO_02008 1.9e-118 yrzF T serine threonine protein kinase
KLOEOPPO_02010 1.4e-51 S Family of unknown function (DUF5412)
KLOEOPPO_02011 1.8e-262 alsT E Sodium alanine symporter
KLOEOPPO_02012 1.9e-127 yebC K transcriptional regulatory protein
KLOEOPPO_02013 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KLOEOPPO_02014 8.3e-157 safA M spore coat assembly protein SafA
KLOEOPPO_02015 3.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KLOEOPPO_02016 1.2e-155 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KLOEOPPO_02017 4.4e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KLOEOPPO_02018 3.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
KLOEOPPO_02019 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
KLOEOPPO_02020 2.2e-162 pheA 4.2.1.51 E Prephenate dehydratase
KLOEOPPO_02021 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KLOEOPPO_02022 1.2e-230 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLOEOPPO_02023 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KLOEOPPO_02024 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KLOEOPPO_02025 4.1e-56 ysxB J ribosomal protein
KLOEOPPO_02026 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KLOEOPPO_02027 9.2e-161 spoIVFB S Stage IV sporulation protein
KLOEOPPO_02028 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KLOEOPPO_02029 4.7e-143 minD D Belongs to the ParA family
KLOEOPPO_02030 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KLOEOPPO_02031 1.4e-84 mreD M shape-determining protein
KLOEOPPO_02032 2.8e-157 mreC M Involved in formation and maintenance of cell shape
KLOEOPPO_02033 1.8e-184 mreB D Rod shape-determining protein MreB
KLOEOPPO_02034 5.9e-126 radC E Belongs to the UPF0758 family
KLOEOPPO_02035 2.8e-102 maf D septum formation protein Maf
KLOEOPPO_02036 3.3e-162 spoIIB S Sporulation related domain
KLOEOPPO_02037 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KLOEOPPO_02038 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KLOEOPPO_02039 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KLOEOPPO_02040 1.6e-25
KLOEOPPO_02041 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KLOEOPPO_02042 1.9e-226 spoVID M stage VI sporulation protein D
KLOEOPPO_02043 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KLOEOPPO_02044 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
KLOEOPPO_02045 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KLOEOPPO_02046 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KLOEOPPO_02047 3.6e-146 hemX O cytochrome C
KLOEOPPO_02048 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KLOEOPPO_02049 1.4e-89 ysxD
KLOEOPPO_02050 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KLOEOPPO_02051 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KLOEOPPO_02052 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KLOEOPPO_02053 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KLOEOPPO_02054 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KLOEOPPO_02055 2.3e-187 ysoA H Tetratricopeptide repeat
KLOEOPPO_02056 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KLOEOPPO_02057 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KLOEOPPO_02058 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KLOEOPPO_02059 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KLOEOPPO_02060 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KLOEOPPO_02061 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
KLOEOPPO_02062 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KLOEOPPO_02064 7.6e-82 ysnE K acetyltransferase
KLOEOPPO_02065 9.1e-134 ysnF S protein conserved in bacteria
KLOEOPPO_02067 1.4e-92 ysnB S Phosphoesterase
KLOEOPPO_02068 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KLOEOPPO_02069 9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KLOEOPPO_02070 2.9e-196 gerM S COG5401 Spore germination protein
KLOEOPPO_02071 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KLOEOPPO_02072 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KLOEOPPO_02073 1.2e-166 L Recombinase
KLOEOPPO_02074 3.6e-44 S YolD-like protein
KLOEOPPO_02075 6.4e-70
KLOEOPPO_02077 1.1e-125 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KLOEOPPO_02078 6e-31 xhlB S SPP1 phage holin
KLOEOPPO_02079 1.5e-27 xhlA S Haemolysin XhlA
KLOEOPPO_02080 5.9e-15 xkdX
KLOEOPPO_02082 5.3e-45 S Domain of unknown function (DUF2479)
KLOEOPPO_02083 1.3e-60
KLOEOPPO_02084 4.6e-107 Z012_12235 S homolog of phage Mu protein gp47
KLOEOPPO_02085 4.8e-23 S Protein of unknown function (DUF2634)
KLOEOPPO_02086 3.6e-23
KLOEOPPO_02087 1e-88
KLOEOPPO_02088 2.8e-31
KLOEOPPO_02089 1e-40 3.5.1.28 M LysM domain
KLOEOPPO_02090 3.2e-127 N phage tail tape measure protein
KLOEOPPO_02091 1.7e-13
KLOEOPPO_02092 1.8e-34
KLOEOPPO_02093 1.4e-102 Z012_02110 S Protein of unknown function (DUF3383)
KLOEOPPO_02094 1.2e-29
KLOEOPPO_02095 5.2e-23
KLOEOPPO_02096 3.6e-48
KLOEOPPO_02097 1.4e-16 S Phage gp6-like head-tail connector protein
KLOEOPPO_02098 6.5e-29 S Phage Mu protein F like protein
KLOEOPPO_02100 1.5e-111 S Phage capsid family
KLOEOPPO_02101 5.7e-66 S Domain of unknown function (DUF4355)
KLOEOPPO_02103 8.2e-159 S Phage portal protein, SPP1 Gp6-like
KLOEOPPO_02104 2e-185 ps334 S Terminase-like family
KLOEOPPO_02105 2e-79 yqaS L DNA packaging
KLOEOPPO_02108 1.5e-16 K Transcriptional regulator
KLOEOPPO_02110 8.9e-71 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KLOEOPPO_02117 1.5e-98 ydiP 2.1.1.37 H C-5 cytosine-specific DNA methylase
KLOEOPPO_02121 8.3e-20 yqaO S Phage-like element PBSX protein XtrA
KLOEOPPO_02123 1.3e-52 S Protein of unknown function (DUF1064)
KLOEOPPO_02125 2.9e-10 S YopX protein
KLOEOPPO_02127 5.5e-120 xkdC L IstB-like ATP binding protein
KLOEOPPO_02128 1.1e-36 3.1.3.16 L DnaD domain protein
KLOEOPPO_02129 9.6e-92 recT L Recombinational DNA repair protein (RecE pathway)
KLOEOPPO_02130 7.1e-106 S YqaJ-like viral recombinase domain
KLOEOPPO_02135 8.6e-83
KLOEOPPO_02136 4.1e-45 S DNA binding
KLOEOPPO_02138 3.2e-13 K Helix-turn-helix XRE-family like proteins
KLOEOPPO_02139 9.4e-25 K sequence-specific DNA binding
KLOEOPPO_02140 8.5e-20
KLOEOPPO_02141 1.2e-48 yqaB E IrrE N-terminal-like domain
KLOEOPPO_02142 1.2e-17 gerE K Transcriptional regulator
KLOEOPPO_02143 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KLOEOPPO_02144 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KLOEOPPO_02145 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KLOEOPPO_02146 2.4e-107 sdhC C succinate dehydrogenase
KLOEOPPO_02147 1.2e-79 yslB S Protein of unknown function (DUF2507)
KLOEOPPO_02148 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KLOEOPPO_02149 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KLOEOPPO_02150 2e-52 trxA O Belongs to the thioredoxin family
KLOEOPPO_02151 1.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KLOEOPPO_02153 2.1e-177 etfA C Electron transfer flavoprotein
KLOEOPPO_02154 4.5e-135 etfB C Electron transfer flavoprotein
KLOEOPPO_02155 9.2e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KLOEOPPO_02156 2.7e-100 fadR K Transcriptional regulator
KLOEOPPO_02157 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KLOEOPPO_02158 7.3e-68 yshE S membrane
KLOEOPPO_02159 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KLOEOPPO_02160 0.0 polX L COG1796 DNA polymerase IV (family X)
KLOEOPPO_02161 1.7e-85 cvpA S membrane protein, required for colicin V production
KLOEOPPO_02162 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KLOEOPPO_02163 1.2e-166 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLOEOPPO_02164 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLOEOPPO_02165 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLOEOPPO_02166 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLOEOPPO_02167 5.8e-32 sspI S Belongs to the SspI family
KLOEOPPO_02168 1.3e-204 ysfB KT regulator
KLOEOPPO_02169 2.7e-263 glcD 1.1.3.15 C Glycolate oxidase subunit
KLOEOPPO_02170 1.8e-256 glcF C Glycolate oxidase
KLOEOPPO_02171 5.3e-52 ysfE 4.4.1.5 E Glyoxalase-like domain
KLOEOPPO_02172 0.0 cstA T Carbon starvation protein
KLOEOPPO_02173 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KLOEOPPO_02174 2.9e-143 araQ G transport system permease
KLOEOPPO_02175 1.4e-167 araP G carbohydrate transport
KLOEOPPO_02176 8.1e-254 araN G carbohydrate transport
KLOEOPPO_02177 4.8e-221 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KLOEOPPO_02178 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KLOEOPPO_02179 5.5e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KLOEOPPO_02180 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KLOEOPPO_02181 2.7e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KLOEOPPO_02182 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KLOEOPPO_02183 7.6e-205 ysdC G COG1363 Cellulase M and related proteins
KLOEOPPO_02184 9.2e-68 ysdB S Sigma-w pathway protein YsdB
KLOEOPPO_02185 7.5e-45 ysdA S Membrane
KLOEOPPO_02186 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KLOEOPPO_02187 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KLOEOPPO_02188 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KLOEOPPO_02190 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KLOEOPPO_02191 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KLOEOPPO_02192 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
KLOEOPPO_02193 0.0 lytS 2.7.13.3 T Histidine kinase
KLOEOPPO_02194 4.7e-148 ysaA S HAD-hyrolase-like
KLOEOPPO_02195 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLOEOPPO_02197 7.1e-158 ytxC S YtxC-like family
KLOEOPPO_02198 4.9e-111 ytxB S SNARE associated Golgi protein
KLOEOPPO_02199 3e-173 dnaI L Primosomal protein DnaI
KLOEOPPO_02200 3.5e-266 dnaB L Membrane attachment protein
KLOEOPPO_02201 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLOEOPPO_02202 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KLOEOPPO_02203 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KLOEOPPO_02204 9.9e-67 ytcD K Transcriptional regulator
KLOEOPPO_02205 2.4e-204 ytbD EGP Major facilitator Superfamily
KLOEOPPO_02206 8.9e-161 ytbE S reductase
KLOEOPPO_02207 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KLOEOPPO_02208 1.1e-107 ytaF P Probably functions as a manganese efflux pump
KLOEOPPO_02209 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KLOEOPPO_02210 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLOEOPPO_02211 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KLOEOPPO_02212 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_02213 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KLOEOPPO_02214 4.1e-242 icd 1.1.1.42 C isocitrate
KLOEOPPO_02215 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KLOEOPPO_02216 4.7e-71 yeaL S membrane
KLOEOPPO_02217 2.6e-192 ytvI S sporulation integral membrane protein YtvI
KLOEOPPO_02218 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KLOEOPPO_02219 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KLOEOPPO_02220 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KLOEOPPO_02221 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KLOEOPPO_02222 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KLOEOPPO_02223 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
KLOEOPPO_02224 0.0 dnaE 2.7.7.7 L DNA polymerase
KLOEOPPO_02225 3.2e-56 ytrH S Sporulation protein YtrH
KLOEOPPO_02226 8.2e-69 ytrI
KLOEOPPO_02227 9.2e-29
KLOEOPPO_02228 3.9e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KLOEOPPO_02229 2.4e-47 ytpI S YtpI-like protein
KLOEOPPO_02230 8e-241 ytoI K transcriptional regulator containing CBS domains
KLOEOPPO_02231 1.4e-156 ytnM S membrane transporter protein
KLOEOPPO_02232 4.2e-239 ytnL 3.5.1.47 E hydrolase activity
KLOEOPPO_02233 9e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
KLOEOPPO_02234 1.8e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KLOEOPPO_02235 2.1e-45 ytnI O COG0695 Glutaredoxin and related proteins
KLOEOPPO_02236 1.7e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KLOEOPPO_02237 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KLOEOPPO_02238 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
KLOEOPPO_02239 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
KLOEOPPO_02240 1.9e-147 tcyK M Bacterial periplasmic substrate-binding proteins
KLOEOPPO_02241 2.8e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
KLOEOPPO_02242 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
KLOEOPPO_02243 3.6e-171 ytlI K LysR substrate binding domain
KLOEOPPO_02244 1.7e-130 ytkL S Belongs to the UPF0173 family
KLOEOPPO_02245 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_02247 4.4e-266 argH 4.3.2.1 E argininosuccinate lyase
KLOEOPPO_02248 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KLOEOPPO_02249 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KLOEOPPO_02250 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLOEOPPO_02251 7.8e-164 ytxK 2.1.1.72 L DNA methylase
KLOEOPPO_02252 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KLOEOPPO_02253 8.7e-70 ytfJ S Sporulation protein YtfJ
KLOEOPPO_02254 1.6e-110 ytfI S Protein of unknown function (DUF2953)
KLOEOPPO_02255 1.6e-85 yteJ S RDD family
KLOEOPPO_02256 3e-179 sppA OU signal peptide peptidase SppA
KLOEOPPO_02257 2.4e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLOEOPPO_02258 0.0 ytcJ S amidohydrolase
KLOEOPPO_02259 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KLOEOPPO_02260 2e-29 sspB S spore protein
KLOEOPPO_02261 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLOEOPPO_02262 5.9e-208 iscS2 2.8.1.7 E Cysteine desulfurase
KLOEOPPO_02263 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
KLOEOPPO_02264 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KLOEOPPO_02265 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KLOEOPPO_02266 1e-108 yttP K Transcriptional regulator
KLOEOPPO_02267 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KLOEOPPO_02268 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KLOEOPPO_02269 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KLOEOPPO_02271 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLOEOPPO_02272 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KLOEOPPO_02273 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KLOEOPPO_02274 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
KLOEOPPO_02275 1.9e-225 acuC BQ histone deacetylase
KLOEOPPO_02276 1.4e-125 motS N Flagellar motor protein
KLOEOPPO_02277 2.1e-146 motA N flagellar motor
KLOEOPPO_02278 1.7e-182 ccpA K catabolite control protein A
KLOEOPPO_02279 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KLOEOPPO_02280 1.3e-54 ytxJ O Protein of unknown function (DUF2847)
KLOEOPPO_02281 6.6e-17 ytxH S COG4980 Gas vesicle protein
KLOEOPPO_02282 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KLOEOPPO_02283 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KLOEOPPO_02284 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KLOEOPPO_02285 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLOEOPPO_02286 9.8e-149 ytpQ S Belongs to the UPF0354 family
KLOEOPPO_02287 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KLOEOPPO_02288 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KLOEOPPO_02289 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KLOEOPPO_02290 9.8e-52 ytzB S small secreted protein
KLOEOPPO_02291 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KLOEOPPO_02292 9.3e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KLOEOPPO_02293 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KLOEOPPO_02294 2e-45 ytzH S YtzH-like protein
KLOEOPPO_02295 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
KLOEOPPO_02296 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KLOEOPPO_02297 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KLOEOPPO_02298 8.5e-165 ytlQ
KLOEOPPO_02299 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KLOEOPPO_02300 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KLOEOPPO_02301 5.1e-270 pepV 3.5.1.18 E Dipeptidase
KLOEOPPO_02302 2.1e-225 pbuO S permease
KLOEOPPO_02303 4.2e-201 ythQ U Bacterial ABC transporter protein EcsB
KLOEOPPO_02304 4.8e-131 ythP V ABC transporter
KLOEOPPO_02305 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KLOEOPPO_02306 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLOEOPPO_02307 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KLOEOPPO_02308 8.2e-232 ytfP S HI0933-like protein
KLOEOPPO_02309 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KLOEOPPO_02310 3.1e-26 yteV S Sporulation protein Cse60
KLOEOPPO_02311 4.5e-115 yteU S Integral membrane protein
KLOEOPPO_02312 6.6e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
KLOEOPPO_02313 1.5e-71 yteS G transport
KLOEOPPO_02314 1.6e-218 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KLOEOPPO_02315 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KLOEOPPO_02316 0.0 ytdP K Transcriptional regulator
KLOEOPPO_02317 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
KLOEOPPO_02318 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
KLOEOPPO_02319 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
KLOEOPPO_02320 2.7e-224 bioI 1.14.14.46 C Cytochrome P450
KLOEOPPO_02321 6.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KLOEOPPO_02322 4.7e-123 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KLOEOPPO_02323 5.1e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KLOEOPPO_02324 4.3e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KLOEOPPO_02325 5.2e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KLOEOPPO_02326 2e-171 ytaP S Acetyl xylan esterase (AXE1)
KLOEOPPO_02327 4.3e-189 msmR K Transcriptional regulator
KLOEOPPO_02328 5.2e-245 msmE G Bacterial extracellular solute-binding protein
KLOEOPPO_02329 6.2e-168 amyD P ABC transporter
KLOEOPPO_02330 2.2e-143 amyC P ABC transporter (permease)
KLOEOPPO_02331 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KLOEOPPO_02332 8.1e-51 ytwF P Sulfurtransferase
KLOEOPPO_02333 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLOEOPPO_02334 7.7e-55 ytvB S Protein of unknown function (DUF4257)
KLOEOPPO_02335 1.5e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KLOEOPPO_02336 2.1e-211 yttB EGP Major facilitator Superfamily
KLOEOPPO_02337 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
KLOEOPPO_02338 0.0 bceB V ABC transporter (permease)
KLOEOPPO_02339 1.1e-138 bceA V ABC transporter, ATP-binding protein
KLOEOPPO_02340 5.6e-186 T PhoQ Sensor
KLOEOPPO_02341 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_02342 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KLOEOPPO_02343 9.1e-127 ytrE V ABC transporter, ATP-binding protein
KLOEOPPO_02344 7e-149
KLOEOPPO_02345 2.1e-153 P ABC-2 family transporter protein
KLOEOPPO_02346 4.2e-161 ytrB P abc transporter atp-binding protein
KLOEOPPO_02347 5.1e-66 ytrA K GntR family transcriptional regulator
KLOEOPPO_02349 6.7e-41 ytzC S Protein of unknown function (DUF2524)
KLOEOPPO_02350 2.3e-189 yhcC S Fe-S oxidoreductase
KLOEOPPO_02351 2.4e-104 ytqB J Putative rRNA methylase
KLOEOPPO_02352 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KLOEOPPO_02353 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
KLOEOPPO_02354 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KLOEOPPO_02355 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KLOEOPPO_02356 0.0 asnB 6.3.5.4 E Asparagine synthase
KLOEOPPO_02357 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KLOEOPPO_02358 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KLOEOPPO_02359 1.2e-38 ytmB S Protein of unknown function (DUF2584)
KLOEOPPO_02360 2.1e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KLOEOPPO_02361 3.2e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KLOEOPPO_02362 1.4e-144 ytlC P ABC transporter
KLOEOPPO_02363 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KLOEOPPO_02364 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KLOEOPPO_02365 5.4e-63 ytkC S Bacteriophage holin family
KLOEOPPO_02366 2.1e-76 dps P Belongs to the Dps family
KLOEOPPO_02368 3.6e-73 ytkA S YtkA-like
KLOEOPPO_02369 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KLOEOPPO_02370 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KLOEOPPO_02371 3.6e-41 rpmE2 J Ribosomal protein L31
KLOEOPPO_02372 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
KLOEOPPO_02373 1.1e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KLOEOPPO_02374 1.1e-24 S Domain of Unknown Function (DUF1540)
KLOEOPPO_02375 2.3e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KLOEOPPO_02376 1.5e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KLOEOPPO_02377 1e-139 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KLOEOPPO_02378 1.7e-168 troA P Belongs to the bacterial solute-binding protein 9 family
KLOEOPPO_02379 7.8e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KLOEOPPO_02380 6.7e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KLOEOPPO_02381 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KLOEOPPO_02382 1.4e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KLOEOPPO_02383 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KLOEOPPO_02384 1.6e-271 menF 5.4.4.2 HQ Isochorismate synthase
KLOEOPPO_02385 2.6e-132 dksA T COG1734 DnaK suppressor protein
KLOEOPPO_02386 1.4e-150 galU 2.7.7.9 M Nucleotidyl transferase
KLOEOPPO_02387 1.6e-241 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KLOEOPPO_02388 3.1e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
KLOEOPPO_02389 1.7e-232 ytcC M Glycosyltransferase Family 4
KLOEOPPO_02391 9.7e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
KLOEOPPO_02392 6.9e-217 cotSA M Glycosyl transferases group 1
KLOEOPPO_02393 4.4e-205 cotI S Spore coat protein
KLOEOPPO_02394 9.3e-75 tspO T membrane
KLOEOPPO_02395 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KLOEOPPO_02396 2.5e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KLOEOPPO_02397 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KLOEOPPO_02398 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KLOEOPPO_02399 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KLOEOPPO_02408 7.8e-08
KLOEOPPO_02409 1.3e-09
KLOEOPPO_02416 2e-08
KLOEOPPO_02423 3.4e-39 S COG NOG14552 non supervised orthologous group
KLOEOPPO_02424 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
KLOEOPPO_02425 2.4e-92 M1-753 M FR47-like protein
KLOEOPPO_02426 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
KLOEOPPO_02427 1.2e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KLOEOPPO_02428 3.9e-84 yuaE S DinB superfamily
KLOEOPPO_02429 7.9e-108 yuaD
KLOEOPPO_02430 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
KLOEOPPO_02431 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KLOEOPPO_02432 1.1e-95 yuaC K Belongs to the GbsR family
KLOEOPPO_02433 2.2e-91 yuaB
KLOEOPPO_02434 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
KLOEOPPO_02435 5.4e-237 ktrB P Potassium
KLOEOPPO_02436 1e-38 yiaA S yiaA/B two helix domain
KLOEOPPO_02437 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLOEOPPO_02438 5.8e-275 yubD P Major Facilitator Superfamily
KLOEOPPO_02439 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
KLOEOPPO_02441 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KLOEOPPO_02442 9.1e-196 yubA S transporter activity
KLOEOPPO_02443 3.3e-183 ygjR S Oxidoreductase
KLOEOPPO_02444 4.4e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
KLOEOPPO_02445 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KLOEOPPO_02446 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KLOEOPPO_02447 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
KLOEOPPO_02448 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
KLOEOPPO_02449 7.3e-238 mcpA NT chemotaxis protein
KLOEOPPO_02450 3.8e-295 mcpA NT chemotaxis protein
KLOEOPPO_02451 3.3e-222 mcpA NT chemotaxis protein
KLOEOPPO_02452 3.2e-225 mcpA NT chemotaxis protein
KLOEOPPO_02453 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KLOEOPPO_02454 1e-35
KLOEOPPO_02455 2.1e-72 yugU S Uncharacterised protein family UPF0047
KLOEOPPO_02456 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KLOEOPPO_02457 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KLOEOPPO_02458 1.4e-116 yugP S Zn-dependent protease
KLOEOPPO_02459 2.3e-38
KLOEOPPO_02460 1.1e-53 mstX S Membrane-integrating protein Mistic
KLOEOPPO_02461 8.2e-182 yugO P COG1226 Kef-type K transport systems
KLOEOPPO_02462 1.4e-71 yugN S YugN-like family
KLOEOPPO_02464 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
KLOEOPPO_02465 3.1e-228 yugK C Dehydrogenase
KLOEOPPO_02466 1.3e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KLOEOPPO_02467 1.1e-34 yuzA S Domain of unknown function (DUF378)
KLOEOPPO_02468 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KLOEOPPO_02469 2.1e-199 yugH 2.6.1.1 E Aminotransferase
KLOEOPPO_02470 1.6e-85 alaR K Transcriptional regulator
KLOEOPPO_02471 2.5e-155 yugF I Hydrolase
KLOEOPPO_02472 1.6e-39 yugE S Domain of unknown function (DUF1871)
KLOEOPPO_02473 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KLOEOPPO_02474 4.6e-233 T PhoQ Sensor
KLOEOPPO_02475 3.3e-70 kapB G Kinase associated protein B
KLOEOPPO_02476 1.9e-115 kapD L the KinA pathway to sporulation
KLOEOPPO_02478 4.2e-184 yuxJ EGP Major facilitator Superfamily
KLOEOPPO_02479 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KLOEOPPO_02480 5.3e-74 yuxK S protein conserved in bacteria
KLOEOPPO_02481 6.3e-78 yufK S Family of unknown function (DUF5366)
KLOEOPPO_02482 1.9e-292 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KLOEOPPO_02483 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
KLOEOPPO_02484 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KLOEOPPO_02485 3.2e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KLOEOPPO_02486 1.9e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
KLOEOPPO_02487 7.8e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
KLOEOPPO_02488 3.1e-232 maeN C COG3493 Na citrate symporter
KLOEOPPO_02489 3.2e-14
KLOEOPPO_02490 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KLOEOPPO_02491 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KLOEOPPO_02492 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KLOEOPPO_02493 4.9e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KLOEOPPO_02494 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KLOEOPPO_02495 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KLOEOPPO_02496 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KLOEOPPO_02497 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
KLOEOPPO_02498 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLOEOPPO_02499 0.0 comP 2.7.13.3 T Histidine kinase
KLOEOPPO_02501 1.7e-128 comQ H Belongs to the FPP GGPP synthase family
KLOEOPPO_02503 1.1e-22 yuzC
KLOEOPPO_02504 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KLOEOPPO_02505 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLOEOPPO_02506 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
KLOEOPPO_02507 7.9e-67 yueI S Protein of unknown function (DUF1694)
KLOEOPPO_02508 2.8e-38 yueH S YueH-like protein
KLOEOPPO_02509 1.7e-31 yueG S Spore germination protein gerPA/gerPF
KLOEOPPO_02510 5.4e-190 yueF S transporter activity
KLOEOPPO_02511 1.3e-69 S Protein of unknown function (DUF2283)
KLOEOPPO_02512 2.9e-24 S Protein of unknown function (DUF2642)
KLOEOPPO_02513 4.8e-96 yueE S phosphohydrolase
KLOEOPPO_02514 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_02515 7.3e-64 yueC S Family of unknown function (DUF5383)
KLOEOPPO_02516 0.0 esaA S type VII secretion protein EsaA
KLOEOPPO_02517 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KLOEOPPO_02518 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
KLOEOPPO_02519 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
KLOEOPPO_02520 2.8e-45 esxA S Belongs to the WXG100 family
KLOEOPPO_02521 6.5e-229 yukF QT Transcriptional regulator
KLOEOPPO_02522 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KLOEOPPO_02523 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
KLOEOPPO_02524 5e-36 mbtH S MbtH-like protein
KLOEOPPO_02525 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_02526 8.9e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KLOEOPPO_02527 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KLOEOPPO_02528 1.2e-224 entC 5.4.4.2 HQ Isochorismate synthase
KLOEOPPO_02529 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KLOEOPPO_02530 1.5e-166 besA S Putative esterase
KLOEOPPO_02531 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
KLOEOPPO_02532 1.7e-92 bioY S Biotin biosynthesis protein
KLOEOPPO_02533 8.7e-211 yuiF S antiporter
KLOEOPPO_02534 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KLOEOPPO_02535 2e-77 yuiD S protein conserved in bacteria
KLOEOPPO_02536 4.7e-117 yuiC S protein conserved in bacteria
KLOEOPPO_02537 1.2e-25 yuiB S Putative membrane protein
KLOEOPPO_02538 1.2e-235 yumB 1.6.99.3 C NADH dehydrogenase
KLOEOPPO_02539 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
KLOEOPPO_02541 7.9e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLOEOPPO_02542 7.2e-115 paiB K Putative FMN-binding domain
KLOEOPPO_02543 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLOEOPPO_02544 3.7e-63 erpA S Belongs to the HesB IscA family
KLOEOPPO_02545 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KLOEOPPO_02546 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KLOEOPPO_02547 3.2e-39 yuzB S Belongs to the UPF0349 family
KLOEOPPO_02548 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
KLOEOPPO_02549 8.7e-56 yuzD S protein conserved in bacteria
KLOEOPPO_02550 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KLOEOPPO_02551 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KLOEOPPO_02552 3.6e-171 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KLOEOPPO_02553 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KLOEOPPO_02554 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
KLOEOPPO_02555 5e-198 yutH S Spore coat protein
KLOEOPPO_02556 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KLOEOPPO_02557 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KLOEOPPO_02558 1e-75 yutE S Protein of unknown function DUF86
KLOEOPPO_02559 9.7e-48 yutD S protein conserved in bacteria
KLOEOPPO_02560 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KLOEOPPO_02561 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KLOEOPPO_02562 4.5e-196 lytH M Peptidase, M23
KLOEOPPO_02563 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
KLOEOPPO_02564 1.1e-47 yunC S Domain of unknown function (DUF1805)
KLOEOPPO_02565 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KLOEOPPO_02566 2e-141 yunE S membrane transporter protein
KLOEOPPO_02567 4.3e-171 yunF S Protein of unknown function DUF72
KLOEOPPO_02568 2.8e-60 yunG
KLOEOPPO_02569 4.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KLOEOPPO_02570 8.3e-301 pucR QT COG2508 Regulator of polyketide synthase expression
KLOEOPPO_02571 1e-230 pbuX F Permease family
KLOEOPPO_02572 4.3e-223 pbuX F xanthine
KLOEOPPO_02573 5.2e-281 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KLOEOPPO_02574 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KLOEOPPO_02575 2.8e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KLOEOPPO_02576 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KLOEOPPO_02577 3.7e-151 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KLOEOPPO_02578 3.1e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KLOEOPPO_02579 2.1e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KLOEOPPO_02581 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KLOEOPPO_02582 6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KLOEOPPO_02583 5e-167 bsn L Ribonuclease
KLOEOPPO_02584 2.2e-204 msmX P Belongs to the ABC transporter superfamily
KLOEOPPO_02585 1.1e-135 yurK K UTRA
KLOEOPPO_02586 3.3e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KLOEOPPO_02587 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
KLOEOPPO_02588 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
KLOEOPPO_02589 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KLOEOPPO_02590 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KLOEOPPO_02591 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KLOEOPPO_02592 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KLOEOPPO_02594 1e-41
KLOEOPPO_02595 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLOEOPPO_02596 3.5e-271 sufB O FeS cluster assembly
KLOEOPPO_02597 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KLOEOPPO_02598 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KLOEOPPO_02599 5.3e-245 sufD O assembly protein SufD
KLOEOPPO_02600 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KLOEOPPO_02601 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KLOEOPPO_02602 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
KLOEOPPO_02603 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
KLOEOPPO_02604 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLOEOPPO_02605 2.4e-56 yusD S SCP-2 sterol transfer family
KLOEOPPO_02606 5.6e-55 traF CO Thioredoxin
KLOEOPPO_02607 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KLOEOPPO_02608 1.1e-39 yusG S Protein of unknown function (DUF2553)
KLOEOPPO_02609 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KLOEOPPO_02610 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KLOEOPPO_02611 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KLOEOPPO_02612 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
KLOEOPPO_02613 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KLOEOPPO_02614 8.1e-09 S YuzL-like protein
KLOEOPPO_02615 8.4e-165 fadM E Proline dehydrogenase
KLOEOPPO_02616 1.5e-39
KLOEOPPO_02617 5.4e-53 yusN M Coat F domain
KLOEOPPO_02618 2.3e-73 yusO K Iron dependent repressor, N-terminal DNA binding domain
KLOEOPPO_02619 3.8e-293 yusP P Major facilitator superfamily
KLOEOPPO_02620 2.7e-64 yusQ S Tautomerase enzyme
KLOEOPPO_02621 1e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KLOEOPPO_02622 1.7e-157 yusT K LysR substrate binding domain
KLOEOPPO_02623 5.6e-39 yusU S Protein of unknown function (DUF2573)
KLOEOPPO_02624 3.9e-153 yusV 3.6.3.34 HP ABC transporter
KLOEOPPO_02625 2.5e-66 S YusW-like protein
KLOEOPPO_02626 3.6e-300 pepF2 E COG1164 Oligoendopeptidase F
KLOEOPPO_02627 1.4e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KLOEOPPO_02628 1.2e-79 dps P Ferritin-like domain
KLOEOPPO_02629 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KLOEOPPO_02630 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_02631 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
KLOEOPPO_02632 4.3e-158 yuxN K Transcriptional regulator
KLOEOPPO_02633 1.6e-260 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KLOEOPPO_02634 1.1e-23 S Protein of unknown function (DUF3970)
KLOEOPPO_02635 3.7e-247 gerAA EG Spore germination protein
KLOEOPPO_02636 9.1e-198 gerAB E Spore germination protein
KLOEOPPO_02637 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
KLOEOPPO_02638 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLOEOPPO_02639 5.5e-187 vraS 2.7.13.3 T Histidine kinase
KLOEOPPO_02640 4.7e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KLOEOPPO_02641 4.8e-125 liaG S Putative adhesin
KLOEOPPO_02642 4e-103 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KLOEOPPO_02643 2.8e-61 liaI S membrane
KLOEOPPO_02644 1.2e-225 yvqJ EGP Major facilitator Superfamily
KLOEOPPO_02645 2.7e-100 yvqK 2.5.1.17 S Adenosyltransferase
KLOEOPPO_02646 5.2e-240 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KLOEOPPO_02647 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_02648 1.3e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KLOEOPPO_02649 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KLOEOPPO_02650 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
KLOEOPPO_02651 0.0 T PhoQ Sensor
KLOEOPPO_02652 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_02653 3.6e-22
KLOEOPPO_02654 1.6e-97 yvrI K RNA polymerase
KLOEOPPO_02655 2.4e-19 S YvrJ protein family
KLOEOPPO_02656 3.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
KLOEOPPO_02657 1.1e-63 yvrL S Regulatory protein YrvL
KLOEOPPO_02658 4e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
KLOEOPPO_02659 1.6e-123 macB V ABC transporter, ATP-binding protein
KLOEOPPO_02660 7.6e-174 M Efflux transporter rnd family, mfp subunit
KLOEOPPO_02661 4.9e-148 fhuC 3.6.3.34 HP ABC transporter
KLOEOPPO_02662 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_02663 7.9e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_02664 1.2e-177 fhuD P ABC transporter
KLOEOPPO_02665 4.9e-236 yvsH E Arginine ornithine antiporter
KLOEOPPO_02666 6.5e-16 S Small spore protein J (Spore_SspJ)
KLOEOPPO_02667 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KLOEOPPO_02668 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KLOEOPPO_02669 4.1e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KLOEOPPO_02670 2.7e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KLOEOPPO_02671 6.9e-119 modB P COG4149 ABC-type molybdate transport system, permease component
KLOEOPPO_02672 1.1e-155 yvgN S reductase
KLOEOPPO_02673 5.4e-86 yvgO
KLOEOPPO_02674 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KLOEOPPO_02675 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KLOEOPPO_02676 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KLOEOPPO_02677 0.0 helD 3.6.4.12 L DNA helicase
KLOEOPPO_02679 2e-106 yvgT S membrane
KLOEOPPO_02680 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
KLOEOPPO_02681 1.6e-104 bdbD O Thioredoxin
KLOEOPPO_02682 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KLOEOPPO_02683 0.0 copA 3.6.3.54 P P-type ATPase
KLOEOPPO_02684 5.9e-29 copZ P Copper resistance protein CopZ
KLOEOPPO_02685 2.2e-48 csoR S transcriptional
KLOEOPPO_02686 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
KLOEOPPO_02687 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KLOEOPPO_02688 0.0 yvaC S Fusaric acid resistance protein-like
KLOEOPPO_02689 5.7e-73 yvaD S Family of unknown function (DUF5360)
KLOEOPPO_02690 5.3e-54 yvaE P Small Multidrug Resistance protein
KLOEOPPO_02691 3.3e-98 K Bacterial regulatory proteins, tetR family
KLOEOPPO_02692 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KLOEOPPO_02694 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KLOEOPPO_02695 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KLOEOPPO_02696 5.6e-143 est 3.1.1.1 S Carboxylesterase
KLOEOPPO_02697 2.4e-23 secG U Preprotein translocase subunit SecG
KLOEOPPO_02698 4.2e-25 yvaM S Serine aminopeptidase, S33
KLOEOPPO_02699 7.9e-102 yvaM S Serine aminopeptidase, S33
KLOEOPPO_02700 7.5e-36 yvzC K Transcriptional
KLOEOPPO_02701 4e-69 K transcriptional
KLOEOPPO_02702 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
KLOEOPPO_02703 2.2e-54 yodB K transcriptional
KLOEOPPO_02704 1.9e-218 NT chemotaxis protein
KLOEOPPO_02705 4.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KLOEOPPO_02706 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KLOEOPPO_02707 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KLOEOPPO_02708 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KLOEOPPO_02709 8.7e-61 yvbF K Belongs to the GbsR family
KLOEOPPO_02710 7.9e-13 S Sporulation delaying protein SdpA
KLOEOPPO_02711 7.6e-172
KLOEOPPO_02712 4.4e-08
KLOEOPPO_02713 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
KLOEOPPO_02714 4.5e-45 sdpR K transcriptional
KLOEOPPO_02715 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KLOEOPPO_02716 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KLOEOPPO_02717 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KLOEOPPO_02718 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KLOEOPPO_02719 1.4e-98 yvbF K Belongs to the GbsR family
KLOEOPPO_02720 6.4e-103 yvbG U UPF0056 membrane protein
KLOEOPPO_02721 8.6e-113 yvbH S YvbH-like oligomerisation region
KLOEOPPO_02722 1.6e-123 exoY M Membrane
KLOEOPPO_02723 0.0 tcaA S response to antibiotic
KLOEOPPO_02724 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
KLOEOPPO_02725 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KLOEOPPO_02726 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KLOEOPPO_02727 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLOEOPPO_02728 6.5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KLOEOPPO_02729 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KLOEOPPO_02730 1.8e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KLOEOPPO_02731 1.6e-252 araE EGP Major facilitator Superfamily
KLOEOPPO_02732 5.5e-203 araR K transcriptional
KLOEOPPO_02733 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KLOEOPPO_02734 5.1e-159 yvbU K Transcriptional regulator
KLOEOPPO_02735 2.7e-155 yvbV EG EamA-like transporter family
KLOEOPPO_02736 1.2e-239 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KLOEOPPO_02737 3.4e-194 yvbX S Glycosyl hydrolase
KLOEOPPO_02738 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KLOEOPPO_02739 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KLOEOPPO_02740 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KLOEOPPO_02741 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLOEOPPO_02742 1.9e-198 desK 2.7.13.3 T Histidine kinase
KLOEOPPO_02743 7.6e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
KLOEOPPO_02744 6.6e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
KLOEOPPO_02745 9.8e-157 rsbQ S Alpha/beta hydrolase family
KLOEOPPO_02746 5.9e-198 rsbU 3.1.3.3 T response regulator
KLOEOPPO_02747 3.2e-250 galA 3.2.1.89 G arabinogalactan
KLOEOPPO_02748 0.0 lacA 3.2.1.23 G beta-galactosidase
KLOEOPPO_02749 7.2e-150 ganQ P transport
KLOEOPPO_02750 5.5e-231 malC P COG1175 ABC-type sugar transport systems, permease components
KLOEOPPO_02751 1.5e-231 cycB G COG2182 Maltose-binding periplasmic proteins domains
KLOEOPPO_02752 1.8e-184 lacR K Transcriptional regulator
KLOEOPPO_02753 2.7e-113 yvfI K COG2186 Transcriptional regulators
KLOEOPPO_02754 2.6e-308 yvfH C L-lactate permease
KLOEOPPO_02755 1.1e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KLOEOPPO_02756 1e-31 yvfG S YvfG protein
KLOEOPPO_02757 3.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
KLOEOPPO_02758 2.5e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KLOEOPPO_02759 1.3e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KLOEOPPO_02760 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KLOEOPPO_02761 2.4e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KLOEOPPO_02762 3.3e-189 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KLOEOPPO_02763 4.4e-205 epsI GM pyruvyl transferase
KLOEOPPO_02764 5.8e-194 epsH GT2 S Glycosyltransferase like family 2
KLOEOPPO_02765 1.1e-206 epsG S EpsG family
KLOEOPPO_02766 3.5e-216 epsF GT4 M Glycosyl transferases group 1
KLOEOPPO_02767 1.6e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KLOEOPPO_02768 2.5e-222 epsD GT4 M Glycosyl transferase 4-like
KLOEOPPO_02769 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KLOEOPPO_02770 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KLOEOPPO_02771 4e-122 ywqC M biosynthesis protein
KLOEOPPO_02772 6.3e-76 slr K transcriptional
KLOEOPPO_02773 1.8e-281 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KLOEOPPO_02775 1.7e-92 padC Q Phenolic acid decarboxylase
KLOEOPPO_02776 6.5e-73 MA20_18690 S Protein of unknown function (DUF3237)
KLOEOPPO_02777 2.2e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KLOEOPPO_02778 2.1e-260 pbpE V Beta-lactamase
KLOEOPPO_02779 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
KLOEOPPO_02780 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KLOEOPPO_02781 1.8e-295 yveA E amino acid
KLOEOPPO_02782 2.6e-106 yvdT K Transcriptional regulator
KLOEOPPO_02783 6.7e-51 ykkC P Small Multidrug Resistance protein
KLOEOPPO_02784 4.1e-50 sugE P Small Multidrug Resistance protein
KLOEOPPO_02785 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
KLOEOPPO_02786 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
KLOEOPPO_02787 2.8e-182 S Patatin-like phospholipase
KLOEOPPO_02789 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KLOEOPPO_02790 1.7e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KLOEOPPO_02791 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KLOEOPPO_02792 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KLOEOPPO_02793 5.9e-155 malA S Protein of unknown function (DUF1189)
KLOEOPPO_02794 6.2e-146 malD P transport
KLOEOPPO_02795 1.7e-243 malC P COG1175 ABC-type sugar transport systems, permease components
KLOEOPPO_02796 4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KLOEOPPO_02797 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KLOEOPPO_02798 8.8e-173 yvdE K Transcriptional regulator
KLOEOPPO_02799 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KLOEOPPO_02800 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
KLOEOPPO_02801 8.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KLOEOPPO_02802 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KLOEOPPO_02803 9.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLOEOPPO_02804 0.0 yxdM V ABC transporter (permease)
KLOEOPPO_02805 7.3e-141 yvcR V ABC transporter, ATP-binding protein
KLOEOPPO_02806 1.5e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KLOEOPPO_02807 8.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_02808 3.3e-32
KLOEOPPO_02809 1.9e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KLOEOPPO_02810 1.6e-36 crh G Phosphocarrier protein Chr
KLOEOPPO_02811 1.4e-170 whiA K May be required for sporulation
KLOEOPPO_02812 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KLOEOPPO_02813 5.7e-166 rapZ S Displays ATPase and GTPase activities
KLOEOPPO_02814 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KLOEOPPO_02815 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KLOEOPPO_02816 1.4e-102 usp CBM50 M protein conserved in bacteria
KLOEOPPO_02817 2.4e-278 S COG0457 FOG TPR repeat
KLOEOPPO_02818 0.0 msbA2 3.6.3.44 V ABC transporter
KLOEOPPO_02820 1e-252
KLOEOPPO_02821 2.1e-70
KLOEOPPO_02822 4.4e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KLOEOPPO_02823 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KLOEOPPO_02824 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KLOEOPPO_02825 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KLOEOPPO_02826 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KLOEOPPO_02827 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KLOEOPPO_02828 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KLOEOPPO_02829 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KLOEOPPO_02830 4.5e-140 yvpB NU protein conserved in bacteria
KLOEOPPO_02831 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
KLOEOPPO_02832 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KLOEOPPO_02833 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KLOEOPPO_02834 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
KLOEOPPO_02835 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KLOEOPPO_02836 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KLOEOPPO_02837 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KLOEOPPO_02838 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KLOEOPPO_02839 3.6e-134 yvoA K transcriptional
KLOEOPPO_02840 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KLOEOPPO_02841 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
KLOEOPPO_02842 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
KLOEOPPO_02843 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
KLOEOPPO_02844 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
KLOEOPPO_02845 2.7e-203 yvmA EGP Major facilitator Superfamily
KLOEOPPO_02846 1.2e-50 yvlD S Membrane
KLOEOPPO_02847 2.6e-26 pspB KT PspC domain
KLOEOPPO_02848 3.4e-168 yvlB S Putative adhesin
KLOEOPPO_02849 8e-49 yvlA
KLOEOPPO_02850 6.7e-34 yvkN
KLOEOPPO_02851 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KLOEOPPO_02852 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KLOEOPPO_02853 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KLOEOPPO_02854 1.2e-30 csbA S protein conserved in bacteria
KLOEOPPO_02855 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KLOEOPPO_02857 7e-101 yvkB K Transcriptional regulator
KLOEOPPO_02858 7.9e-228 yvkA EGP Major facilitator Superfamily
KLOEOPPO_02859 1.1e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KLOEOPPO_02860 5.3e-56 swrA S Swarming motility protein
KLOEOPPO_02861 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KLOEOPPO_02862 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KLOEOPPO_02863 1.6e-123 ftsE D cell division ATP-binding protein FtsE
KLOEOPPO_02864 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
KLOEOPPO_02865 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KLOEOPPO_02866 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KLOEOPPO_02867 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KLOEOPPO_02868 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KLOEOPPO_02869 2.8e-66
KLOEOPPO_02870 1.9e-08 fliT S bacterial-type flagellum organization
KLOEOPPO_02871 2.9e-69 fliS N flagellar protein FliS
KLOEOPPO_02872 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KLOEOPPO_02873 6.1e-57 flaG N flagellar protein FlaG
KLOEOPPO_02874 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KLOEOPPO_02875 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KLOEOPPO_02876 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KLOEOPPO_02877 2.6e-50 yviE
KLOEOPPO_02878 1.1e-156 flgL N Belongs to the bacterial flagellin family
KLOEOPPO_02879 1.2e-264 flgK N flagellar hook-associated protein
KLOEOPPO_02880 7.1e-78 flgN NOU FlgN protein
KLOEOPPO_02881 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
KLOEOPPO_02882 7e-74 yvyF S flagellar protein
KLOEOPPO_02883 1.2e-126 comFC S Phosphoribosyl transferase domain
KLOEOPPO_02884 3.7e-45 comFB S Late competence development protein ComFB
KLOEOPPO_02885 1.8e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KLOEOPPO_02886 7.3e-155 degV S protein conserved in bacteria
KLOEOPPO_02887 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLOEOPPO_02888 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KLOEOPPO_02889 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KLOEOPPO_02890 6e-163 yvhJ K Transcriptional regulator
KLOEOPPO_02891 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KLOEOPPO_02892 8.6e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KLOEOPPO_02893 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
KLOEOPPO_02894 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
KLOEOPPO_02895 8.2e-252 tuaE M Teichuronic acid biosynthesis protein
KLOEOPPO_02896 4.4e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KLOEOPPO_02897 2e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KLOEOPPO_02898 7.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KLOEOPPO_02899 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KLOEOPPO_02900 3.3e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KLOEOPPO_02901 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KLOEOPPO_02902 6e-38
KLOEOPPO_02903 1.8e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KLOEOPPO_02904 1.6e-213 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KLOEOPPO_02905 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KLOEOPPO_02906 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KLOEOPPO_02907 8.1e-257 ggaA M Glycosyltransferase like family 2
KLOEOPPO_02909 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KLOEOPPO_02910 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KLOEOPPO_02911 1.1e-150 tagG GM Transport permease protein
KLOEOPPO_02912 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KLOEOPPO_02913 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
KLOEOPPO_02914 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KLOEOPPO_02915 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KLOEOPPO_02916 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KLOEOPPO_02917 1.2e-260
KLOEOPPO_02918 1.6e-216 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLOEOPPO_02919 2.1e-190 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KLOEOPPO_02920 7.4e-264 gerBA EG Spore germination protein
KLOEOPPO_02921 5.4e-198 gerBB E Spore germination protein
KLOEOPPO_02922 6e-213 gerAC S Spore germination protein
KLOEOPPO_02923 1.2e-247 ywtG EGP Major facilitator Superfamily
KLOEOPPO_02924 1.1e-170 ywtF K Transcriptional regulator
KLOEOPPO_02925 2.9e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KLOEOPPO_02926 4.5e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KLOEOPPO_02927 3.6e-21 ywtC
KLOEOPPO_02928 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KLOEOPPO_02929 8.6e-70 pgsC S biosynthesis protein
KLOEOPPO_02930 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KLOEOPPO_02931 5.5e-178 rbsR K transcriptional
KLOEOPPO_02932 1.9e-161 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLOEOPPO_02933 1.2e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KLOEOPPO_02934 8.6e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KLOEOPPO_02935 6e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
KLOEOPPO_02936 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KLOEOPPO_02937 1e-93 batE T Sh3 type 3 domain protein
KLOEOPPO_02938 3.6e-48 ywsA S Protein of unknown function (DUF3892)
KLOEOPPO_02939 4.4e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
KLOEOPPO_02940 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KLOEOPPO_02941 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KLOEOPPO_02942 1.1e-169 alsR K LysR substrate binding domain
KLOEOPPO_02943 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KLOEOPPO_02944 7.5e-126 ywrJ
KLOEOPPO_02945 2.2e-130 cotB
KLOEOPPO_02946 1.4e-206 cotH M Spore Coat
KLOEOPPO_02947 1.3e-12
KLOEOPPO_02948 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KLOEOPPO_02949 5e-54 S Domain of unknown function (DUF4181)
KLOEOPPO_02950 1.8e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KLOEOPPO_02951 8e-82 ywrC K Transcriptional regulator
KLOEOPPO_02952 1.6e-103 ywrB P Chromate transporter
KLOEOPPO_02953 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
KLOEOPPO_02955 1.1e-100 ywqN S NAD(P)H-dependent
KLOEOPPO_02956 4.9e-162 K Transcriptional regulator
KLOEOPPO_02957 3e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KLOEOPPO_02958 1.9e-24
KLOEOPPO_02959 2.1e-242 ywqJ S Pre-toxin TG
KLOEOPPO_02960 2.5e-37 ywqI S Family of unknown function (DUF5344)
KLOEOPPO_02961 9.7e-23 S Domain of unknown function (DUF5082)
KLOEOPPO_02962 1.7e-150 ywqG S Domain of unknown function (DUF1963)
KLOEOPPO_02963 5.2e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KLOEOPPO_02964 8.7e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KLOEOPPO_02965 2.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KLOEOPPO_02966 2e-116 ywqC M biosynthesis protein
KLOEOPPO_02967 1.2e-17
KLOEOPPO_02968 1.3e-306 ywqB S SWIM zinc finger
KLOEOPPO_02969 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KLOEOPPO_02970 2.2e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KLOEOPPO_02971 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
KLOEOPPO_02972 1.4e-56 ssbB L Single-stranded DNA-binding protein
KLOEOPPO_02973 3.8e-66 ywpG
KLOEOPPO_02974 1.1e-66 ywpF S YwpF-like protein
KLOEOPPO_02975 2.7e-46 srtA 3.4.22.70 M Sortase family
KLOEOPPO_02976 4.9e-146 ywpD T Histidine kinase
KLOEOPPO_02977 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KLOEOPPO_02978 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KLOEOPPO_02979 7.5e-197 S aspartate phosphatase
KLOEOPPO_02980 5.8e-141 flhP N flagellar basal body
KLOEOPPO_02981 1.7e-124 flhO N flagellar basal body
KLOEOPPO_02982 3.5e-180 mbl D Rod shape-determining protein
KLOEOPPO_02983 3e-44 spoIIID K Stage III sporulation protein D
KLOEOPPO_02984 7.9e-70 ywoH K COG1846 Transcriptional regulators
KLOEOPPO_02985 6e-211 ywoG EGP Major facilitator Superfamily
KLOEOPPO_02986 2.8e-231 ywoF P Right handed beta helix region
KLOEOPPO_02987 1.5e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KLOEOPPO_02988 6.3e-241 ywoD EGP Major facilitator superfamily
KLOEOPPO_02989 2e-103 phzA Q Isochorismatase family
KLOEOPPO_02990 2.2e-76
KLOEOPPO_02991 2.5e-225 amt P Ammonium transporter
KLOEOPPO_02992 1.6e-58 nrgB K Belongs to the P(II) protein family
KLOEOPPO_02993 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KLOEOPPO_02994 3.5e-73 ywnJ S VanZ like family
KLOEOPPO_02995 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KLOEOPPO_02996 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KLOEOPPO_02997 2.7e-14 ywnC S Family of unknown function (DUF5362)
KLOEOPPO_02998 2.2e-70 ywnF S Family of unknown function (DUF5392)
KLOEOPPO_02999 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLOEOPPO_03000 1.6e-143 mta K transcriptional
KLOEOPPO_03001 1.7e-58 ywnC S Family of unknown function (DUF5362)
KLOEOPPO_03002 2.6e-112 ywnB S NAD(P)H-binding
KLOEOPPO_03003 1.7e-64 ywnA K Transcriptional regulator
KLOEOPPO_03004 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KLOEOPPO_03005 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KLOEOPPO_03006 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KLOEOPPO_03008 3.8e-11 csbD K CsbD-like
KLOEOPPO_03009 3e-84 ywmF S Peptidase M50
KLOEOPPO_03010 1.3e-103 S response regulator aspartate phosphatase
KLOEOPPO_03011 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KLOEOPPO_03012 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KLOEOPPO_03014 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KLOEOPPO_03015 1.5e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KLOEOPPO_03016 3.2e-176 spoIID D Stage II sporulation protein D
KLOEOPPO_03017 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLOEOPPO_03018 2.9e-131 ywmB S TATA-box binding
KLOEOPPO_03019 1.3e-32 ywzB S membrane
KLOEOPPO_03020 3.1e-86 ywmA
KLOEOPPO_03021 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KLOEOPPO_03022 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KLOEOPPO_03023 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KLOEOPPO_03024 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KLOEOPPO_03025 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLOEOPPO_03026 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KLOEOPPO_03027 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLOEOPPO_03028 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
KLOEOPPO_03029 2.5e-62 atpI S ATP synthase
KLOEOPPO_03030 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KLOEOPPO_03031 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KLOEOPPO_03032 7.2e-95 ywlG S Belongs to the UPF0340 family
KLOEOPPO_03033 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KLOEOPPO_03034 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLOEOPPO_03035 1.7e-91 mntP P Probably functions as a manganese efflux pump
KLOEOPPO_03036 8.1e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KLOEOPPO_03037 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KLOEOPPO_03038 6.1e-112 spoIIR S stage II sporulation protein R
KLOEOPPO_03039 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
KLOEOPPO_03041 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KLOEOPPO_03042 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLOEOPPO_03043 9.1e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLOEOPPO_03044 3.5e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KLOEOPPO_03045 1.5e-159 ywkB S Membrane transport protein
KLOEOPPO_03046 0.0 sfcA 1.1.1.38 C malic enzyme
KLOEOPPO_03047 7e-104 tdk 2.7.1.21 F thymidine kinase
KLOEOPPO_03048 1.1e-32 rpmE J Binds the 23S rRNA
KLOEOPPO_03049 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KLOEOPPO_03050 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KLOEOPPO_03051 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLOEOPPO_03052 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KLOEOPPO_03053 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KLOEOPPO_03054 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
KLOEOPPO_03055 1.8e-90 ywjG S Domain of unknown function (DUF2529)
KLOEOPPO_03056 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KLOEOPPO_03057 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KLOEOPPO_03058 1.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KLOEOPPO_03059 0.0 fadF C COG0247 Fe-S oxidoreductase
KLOEOPPO_03060 5.2e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KLOEOPPO_03061 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KLOEOPPO_03062 2.7e-42 ywjC
KLOEOPPO_03063 4.8e-96 ywjB H RibD C-terminal domain
KLOEOPPO_03064 0.0 ywjA V ABC transporter
KLOEOPPO_03065 1.9e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLOEOPPO_03066 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
KLOEOPPO_03067 2.4e-93 narJ 1.7.5.1 C nitrate reductase
KLOEOPPO_03068 1.9e-296 narH 1.7.5.1 C Nitrate reductase, beta
KLOEOPPO_03069 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KLOEOPPO_03070 7e-86 arfM T cyclic nucleotide binding
KLOEOPPO_03071 4.3e-140 ywiC S YwiC-like protein
KLOEOPPO_03072 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
KLOEOPPO_03073 3.9e-213 narK P COG2223 Nitrate nitrite transporter
KLOEOPPO_03074 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KLOEOPPO_03075 4.7e-73 ywiB S protein conserved in bacteria
KLOEOPPO_03076 1e-07 S Bacteriocin subtilosin A
KLOEOPPO_03077 3.8e-270 C Fe-S oxidoreductases
KLOEOPPO_03079 9.7e-132 cbiO V ABC transporter
KLOEOPPO_03080 1e-232 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KLOEOPPO_03081 2.5e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
KLOEOPPO_03082 2.9e-248 L Peptidase, M16
KLOEOPPO_03084 1.5e-242 ywhL CO amine dehydrogenase activity
KLOEOPPO_03085 7.1e-192 ywhK CO amine dehydrogenase activity
KLOEOPPO_03086 2.3e-79 S aspartate phosphatase
KLOEOPPO_03088 1.6e-168 speB 3.5.3.11 E Belongs to the arginase family
KLOEOPPO_03089 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KLOEOPPO_03090 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KLOEOPPO_03091 8.9e-95 ywhD S YwhD family
KLOEOPPO_03092 3.3e-118 ywhC S Peptidase family M50
KLOEOPPO_03093 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KLOEOPPO_03094 9.5e-71 ywhA K Transcriptional regulator
KLOEOPPO_03095 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLOEOPPO_03097 2e-237 mmr U Major Facilitator Superfamily
KLOEOPPO_03098 1.5e-77 yffB K Transcriptional regulator
KLOEOPPO_03099 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
KLOEOPPO_03100 4.3e-255 ywfO S COG1078 HD superfamily phosphohydrolases
KLOEOPPO_03101 3.1e-36 ywzC S Belongs to the UPF0741 family
KLOEOPPO_03102 3e-110 rsfA_1
KLOEOPPO_03103 1.2e-158 ywfM EG EamA-like transporter family
KLOEOPPO_03104 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KLOEOPPO_03105 2.1e-155 cysL K Transcriptional regulator
KLOEOPPO_03106 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KLOEOPPO_03107 1.1e-146 ywfI C May function as heme-dependent peroxidase
KLOEOPPO_03108 1.9e-136 IQ Enoyl-(Acyl carrier protein) reductase
KLOEOPPO_03109 2.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
KLOEOPPO_03110 1.6e-208 bacE EGP Major facilitator Superfamily
KLOEOPPO_03111 3e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KLOEOPPO_03112 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_03113 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KLOEOPPO_03114 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KLOEOPPO_03115 4.6e-206 ywfA EGP Major facilitator Superfamily
KLOEOPPO_03116 5.1e-251 lysP E amino acid
KLOEOPPO_03117 0.0 rocB E arginine degradation protein
KLOEOPPO_03118 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KLOEOPPO_03119 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KLOEOPPO_03120 1.8e-78
KLOEOPPO_03121 3.5e-87 spsL 5.1.3.13 M Spore Coat
KLOEOPPO_03122 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KLOEOPPO_03123 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KLOEOPPO_03124 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KLOEOPPO_03125 1.7e-190 spsG M Spore Coat
KLOEOPPO_03126 9.7e-132 spsF M Spore Coat
KLOEOPPO_03127 3.2e-214 spsE 2.5.1.56 M acid synthase
KLOEOPPO_03128 4e-164 spsD 2.3.1.210 K Spore Coat
KLOEOPPO_03129 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
KLOEOPPO_03130 1.5e-266 spsB M Capsule polysaccharide biosynthesis protein
KLOEOPPO_03131 1.8e-144 spsA M Spore Coat
KLOEOPPO_03132 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KLOEOPPO_03133 4.3e-59 ywdK S small membrane protein
KLOEOPPO_03134 8.3e-238 ywdJ F Xanthine uracil
KLOEOPPO_03135 7.7e-49 ywdI S Family of unknown function (DUF5327)
KLOEOPPO_03136 7.5e-258 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KLOEOPPO_03137 3.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KLOEOPPO_03138 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
KLOEOPPO_03139 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KLOEOPPO_03140 2e-28 ywdA
KLOEOPPO_03141 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
KLOEOPPO_03142 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KLOEOPPO_03143 1e-139 focA P Formate/nitrite transporter
KLOEOPPO_03144 7e-150 sacT K transcriptional antiterminator
KLOEOPPO_03146 0.0 vpr O Belongs to the peptidase S8 family
KLOEOPPO_03147 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KLOEOPPO_03148 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KLOEOPPO_03149 8.6e-202 rodA D Belongs to the SEDS family
KLOEOPPO_03150 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
KLOEOPPO_03151 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KLOEOPPO_03152 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KLOEOPPO_03153 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KLOEOPPO_03154 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KLOEOPPO_03155 1e-35 ywzA S membrane
KLOEOPPO_03156 3.4e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KLOEOPPO_03157 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KLOEOPPO_03158 9.5e-60 gtcA S GtrA-like protein
KLOEOPPO_03159 2.2e-122 ywcC K transcriptional regulator
KLOEOPPO_03161 2.9e-48 ywcB S Protein of unknown function, DUF485
KLOEOPPO_03162 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLOEOPPO_03163 1.8e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KLOEOPPO_03164 3.2e-223 ywbN P Dyp-type peroxidase family protein
KLOEOPPO_03165 2.1e-181 ycdO P periplasmic lipoprotein involved in iron transport
KLOEOPPO_03166 3.4e-253 P COG0672 High-affinity Fe2 Pb2 permease
KLOEOPPO_03167 2.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KLOEOPPO_03168 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KLOEOPPO_03169 5.8e-153 ywbI K Transcriptional regulator
KLOEOPPO_03170 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KLOEOPPO_03171 2.3e-111 ywbG M effector of murein hydrolase
KLOEOPPO_03172 1.3e-208 ywbF EGP Major facilitator Superfamily
KLOEOPPO_03173 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
KLOEOPPO_03174 2.7e-219 ywbD 2.1.1.191 J Methyltransferase
KLOEOPPO_03175 9.9e-67 ywbC 4.4.1.5 E glyoxalase
KLOEOPPO_03176 9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
KLOEOPPO_03177 8.4e-63 ywbB S Protein of unknown function (DUF2711)
KLOEOPPO_03178 2.1e-43 ywbB S Protein of unknown function (DUF2711)
KLOEOPPO_03179 6.4e-246 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLOEOPPO_03180 1.1e-16 epr 3.4.21.62 O Belongs to the peptidase S8 family
KLOEOPPO_03181 1.1e-226 epr 3.4.21.62 O Belongs to the peptidase S8 family
KLOEOPPO_03182 2.2e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KLOEOPPO_03183 1.2e-152 sacY K transcriptional antiterminator
KLOEOPPO_03184 1e-167 gspA M General stress
KLOEOPPO_03185 5.7e-124 ywaF S Integral membrane protein
KLOEOPPO_03186 4e-87 ywaE K Transcriptional regulator
KLOEOPPO_03187 2.4e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLOEOPPO_03188 5.7e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
KLOEOPPO_03189 3.1e-92 K Helix-turn-helix XRE-family like proteins
KLOEOPPO_03190 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
KLOEOPPO_03191 1e-130 ynfM EGP Major facilitator Superfamily
KLOEOPPO_03192 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
KLOEOPPO_03193 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KLOEOPPO_03194 5e-14 S D-Ala-teichoic acid biosynthesis protein
KLOEOPPO_03195 6.7e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_03196 1.4e-231 dltB M membrane protein involved in D-alanine export
KLOEOPPO_03197 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_03198 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KLOEOPPO_03199 1.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KLOEOPPO_03200 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KLOEOPPO_03201 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KLOEOPPO_03202 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KLOEOPPO_03203 2.4e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLOEOPPO_03204 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KLOEOPPO_03205 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KLOEOPPO_03206 1.1e-19 yxzF
KLOEOPPO_03207 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KLOEOPPO_03208 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KLOEOPPO_03209 5.4e-212 yxlH EGP Major facilitator Superfamily
KLOEOPPO_03210 4.4e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KLOEOPPO_03211 4.1e-164 yxlF V ABC transporter, ATP-binding protein
KLOEOPPO_03212 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
KLOEOPPO_03213 1.2e-31
KLOEOPPO_03214 1.5e-47 yxlC S Family of unknown function (DUF5345)
KLOEOPPO_03215 1.1e-84 sigY K Belongs to the sigma-70 factor family. ECF subfamily
KLOEOPPO_03216 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KLOEOPPO_03217 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KLOEOPPO_03218 0.0 cydD V ATP-binding protein
KLOEOPPO_03219 0.0 cydD V ATP-binding
KLOEOPPO_03220 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KLOEOPPO_03221 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
KLOEOPPO_03222 1.5e-229 cimH C COG3493 Na citrate symporter
KLOEOPPO_03223 0.0 3.4.24.84 O Peptidase family M48
KLOEOPPO_03225 4.7e-154 yxkH G Polysaccharide deacetylase
KLOEOPPO_03226 5.9e-205 msmK P Belongs to the ABC transporter superfamily
KLOEOPPO_03227 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
KLOEOPPO_03228 1e-240 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KLOEOPPO_03229 7.3e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KLOEOPPO_03230 2.8e-74 yxkC S Domain of unknown function (DUF4352)
KLOEOPPO_03231 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KLOEOPPO_03232 6.9e-78 S Protein of unknown function (DUF1453)
KLOEOPPO_03233 1.6e-190 yxjM T Signal transduction histidine kinase
KLOEOPPO_03234 4.9e-114 K helix_turn_helix, Lux Regulon
KLOEOPPO_03235 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KLOEOPPO_03238 1.6e-85 yxjI S LURP-one-related
KLOEOPPO_03239 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
KLOEOPPO_03240 1.7e-218 yxjG 2.1.1.14 E Methionine synthase
KLOEOPPO_03241 6.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KLOEOPPO_03242 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KLOEOPPO_03243 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KLOEOPPO_03244 8e-39 yxjC EG COG2610 H gluconate symporter and related permeases
KLOEOPPO_03245 2.5e-198 yxjC EG COG2610 H gluconate symporter and related permeases
KLOEOPPO_03246 2.9e-159 rlmA 2.1.1.187 Q Methyltransferase domain
KLOEOPPO_03247 2.7e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KLOEOPPO_03248 3e-103 T Domain of unknown function (DUF4163)
KLOEOPPO_03249 3e-47 yxiS
KLOEOPPO_03250 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KLOEOPPO_03251 9.5e-223 citH C Citrate transporter
KLOEOPPO_03252 1.1e-143 exoK GH16 M licheninase activity
KLOEOPPO_03253 1.2e-149 licT K transcriptional antiterminator
KLOEOPPO_03254 1.5e-110
KLOEOPPO_03255 6.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
KLOEOPPO_03256 1.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KLOEOPPO_03257 3.7e-210 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
KLOEOPPO_03260 5.7e-46 yxiJ S YxiJ-like protein
KLOEOPPO_03261 1.6e-93 yxiI S Protein of unknown function (DUF2716)
KLOEOPPO_03262 2e-139
KLOEOPPO_03263 3.7e-75 yxiG
KLOEOPPO_03264 6.4e-63
KLOEOPPO_03265 1.7e-84
KLOEOPPO_03266 1.5e-71 yxxG
KLOEOPPO_03267 0.0 wapA M COG3209 Rhs family protein
KLOEOPPO_03268 6.2e-163 yxxF EG EamA-like transporter family
KLOEOPPO_03269 5.4e-72 yxiE T Belongs to the universal stress protein A family
KLOEOPPO_03270 7.2e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KLOEOPPO_03271 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KLOEOPPO_03272 5.5e-53
KLOEOPPO_03273 9.2e-215 S nuclease activity
KLOEOPPO_03274 4e-38 yxiC S Family of unknown function (DUF5344)
KLOEOPPO_03275 4.6e-21 S Domain of unknown function (DUF5082)
KLOEOPPO_03276 1.5e-277 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KLOEOPPO_03277 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KLOEOPPO_03278 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
KLOEOPPO_03279 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KLOEOPPO_03280 2e-236 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
KLOEOPPO_03281 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KLOEOPPO_03282 2.2e-249 lysP E amino acid
KLOEOPPO_03283 3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KLOEOPPO_03284 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KLOEOPPO_03285 3e-111 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KLOEOPPO_03286 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KLOEOPPO_03287 6.7e-153 yxxB S Domain of Unknown Function (DUF1206)
KLOEOPPO_03288 7.5e-200 eutH E Ethanolamine utilisation protein, EutH
KLOEOPPO_03289 6.2e-249 yxeQ S MmgE/PrpD family
KLOEOPPO_03290 6.1e-213 yxeP 3.5.1.47 E hydrolase activity
KLOEOPPO_03291 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
KLOEOPPO_03292 1.2e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
KLOEOPPO_03293 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
KLOEOPPO_03294 1.6e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLOEOPPO_03295 2.8e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KLOEOPPO_03296 1e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KLOEOPPO_03297 6.2e-151 yidA S hydrolases of the HAD superfamily
KLOEOPPO_03300 1.3e-20 yxeE
KLOEOPPO_03301 5.6e-16 yxeD
KLOEOPPO_03302 8.5e-69
KLOEOPPO_03303 1.3e-176 fhuD P ABC transporter
KLOEOPPO_03304 1.5e-58 yxeA S Protein of unknown function (DUF1093)
KLOEOPPO_03305 0.0 yxdM V ABC transporter (permease)
KLOEOPPO_03306 9.4e-141 yxdL V ABC transporter, ATP-binding protein
KLOEOPPO_03307 2.6e-180 T PhoQ Sensor
KLOEOPPO_03308 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_03309 5.1e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KLOEOPPO_03310 3.3e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KLOEOPPO_03311 8.6e-167 iolH G Xylose isomerase-like TIM barrel
KLOEOPPO_03312 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KLOEOPPO_03313 6.2e-233 iolF EGP Major facilitator Superfamily
KLOEOPPO_03314 8e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KLOEOPPO_03315 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KLOEOPPO_03316 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KLOEOPPO_03317 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KLOEOPPO_03318 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KLOEOPPO_03319 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
KLOEOPPO_03320 8.3e-176 iolS C Aldo keto reductase
KLOEOPPO_03322 8.3e-48 yxcD S Protein of unknown function (DUF2653)
KLOEOPPO_03323 9.6e-245 csbC EGP Major facilitator Superfamily
KLOEOPPO_03324 0.0 htpG O Molecular chaperone. Has ATPase activity
KLOEOPPO_03326 8.2e-151 IQ Enoyl-(Acyl carrier protein) reductase
KLOEOPPO_03327 1.5e-206 yxbF K Bacterial regulatory proteins, tetR family
KLOEOPPO_03328 1.9e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KLOEOPPO_03329 4e-12 yxaI S membrane protein domain
KLOEOPPO_03330 1.2e-92 S PQQ-like domain
KLOEOPPO_03331 3.5e-65 S Family of unknown function (DUF5391)
KLOEOPPO_03332 6.9e-75 yxaI S membrane protein domain
KLOEOPPO_03333 6.7e-226 P Protein of unknown function (DUF418)
KLOEOPPO_03334 3.2e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
KLOEOPPO_03335 6e-100 yxaF K Transcriptional regulator
KLOEOPPO_03336 5.2e-198 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KLOEOPPO_03337 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
KLOEOPPO_03338 5.2e-50 S LrgA family
KLOEOPPO_03339 6.5e-117 yxaC M effector of murein hydrolase
KLOEOPPO_03340 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
KLOEOPPO_03341 2.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KLOEOPPO_03342 7.3e-127 gntR K transcriptional
KLOEOPPO_03343 1.2e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KLOEOPPO_03344 5e-230 gntP EG COG2610 H gluconate symporter and related permeases
KLOEOPPO_03345 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KLOEOPPO_03346 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KLOEOPPO_03347 1.9e-286 ahpF O Alkyl hydroperoxide reductase
KLOEOPPO_03348 2e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KLOEOPPO_03349 5e-12 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
KLOEOPPO_03350 1.5e-19 bglF G phosphotransferase system
KLOEOPPO_03351 2.5e-124 yydK K Transcriptional regulator
KLOEOPPO_03352 1.6e-118 S ABC-2 family transporter protein
KLOEOPPO_03353 1e-108 prrC P ABC transporter
KLOEOPPO_03354 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KLOEOPPO_03355 0.0 O growth
KLOEOPPO_03356 1.2e-120 O growth
KLOEOPPO_03357 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KLOEOPPO_03358 1.1e-09 S YyzF-like protein
KLOEOPPO_03359 1.3e-67
KLOEOPPO_03360 1.1e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KLOEOPPO_03362 2.1e-33 yycQ S Protein of unknown function (DUF2651)
KLOEOPPO_03363 4.6e-208 yycP
KLOEOPPO_03364 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KLOEOPPO_03365 2.2e-84 yycN 2.3.1.128 K Acetyltransferase
KLOEOPPO_03366 1.5e-187 S aspartate phosphatase
KLOEOPPO_03368 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KLOEOPPO_03369 1e-260 rocE E amino acid
KLOEOPPO_03370 1.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KLOEOPPO_03371 2.4e-256 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KLOEOPPO_03372 6.7e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
KLOEOPPO_03373 1.5e-94 K PFAM response regulator receiver
KLOEOPPO_03374 2.6e-73 S Peptidase propeptide and YPEB domain
KLOEOPPO_03375 3.2e-33 S Peptidase propeptide and YPEB domain
KLOEOPPO_03376 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KLOEOPPO_03377 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KLOEOPPO_03378 7.3e-155 yycI S protein conserved in bacteria
KLOEOPPO_03379 5.2e-259 yycH S protein conserved in bacteria
KLOEOPPO_03380 0.0 vicK 2.7.13.3 T Histidine kinase
KLOEOPPO_03381 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_03386 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KLOEOPPO_03387 2.6e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLOEOPPO_03388 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KLOEOPPO_03389 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KLOEOPPO_03391 1.9e-15 yycC K YycC-like protein
KLOEOPPO_03392 7.1e-220 yeaN P COG2807 Cyanate permease
KLOEOPPO_03393 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KLOEOPPO_03394 2.2e-73 rplI J binds to the 23S rRNA
KLOEOPPO_03395 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KLOEOPPO_03396 2.9e-160 yybS S membrane
KLOEOPPO_03398 3.9e-84 cotF M Spore coat protein
KLOEOPPO_03399 1.7e-66 ydeP3 K Transcriptional regulator
KLOEOPPO_03400 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KLOEOPPO_03401 7.3e-61
KLOEOPPO_03403 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
KLOEOPPO_03404 4.3e-111 K TipAS antibiotic-recognition domain
KLOEOPPO_03405 2.6e-122
KLOEOPPO_03406 6.5e-66 yybH S SnoaL-like domain
KLOEOPPO_03407 4.8e-122 yybG S Pentapeptide repeat-containing protein
KLOEOPPO_03408 4.8e-216 ynfM EGP Major facilitator Superfamily
KLOEOPPO_03409 2.6e-163 yybE K Transcriptional regulator
KLOEOPPO_03410 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
KLOEOPPO_03411 2.1e-74 yybC
KLOEOPPO_03412 2.6e-123 S Metallo-beta-lactamase superfamily
KLOEOPPO_03413 5.6e-77 yybA 2.3.1.57 K transcriptional
KLOEOPPO_03414 2.9e-70 yjcF S Acetyltransferase (GNAT) domain
KLOEOPPO_03415 3.2e-96 yyaS S Membrane
KLOEOPPO_03416 2.1e-91 yyaR K Acetyltransferase (GNAT) domain
KLOEOPPO_03417 3.5e-66 yyaQ S YjbR
KLOEOPPO_03418 6.7e-104 yyaP 1.5.1.3 H RibD C-terminal domain
KLOEOPPO_03419 3.3e-245 tetL EGP Major facilitator Superfamily
KLOEOPPO_03421 2.6e-13 S Putative amidase domain
KLOEOPPO_03422 5.1e-61 yyaN K MerR HTH family regulatory protein
KLOEOPPO_03423 4.4e-161 yyaM EG EamA-like transporter family
KLOEOPPO_03424 3.4e-21 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KLOEOPPO_03425 9.7e-67 yrhP E LysE type translocator
KLOEOPPO_03426 4.4e-24 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KLOEOPPO_03427 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KLOEOPPO_03428 7.5e-166 yyaK S CAAX protease self-immunity
KLOEOPPO_03429 6.1e-244 EGP Major facilitator superfamily
KLOEOPPO_03430 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
KLOEOPPO_03431 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLOEOPPO_03432 3.6e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KLOEOPPO_03433 1.4e-141 xth 3.1.11.2 L exodeoxyribonuclease III
KLOEOPPO_03434 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KLOEOPPO_03435 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLOEOPPO_03436 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
KLOEOPPO_03437 5.7e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KLOEOPPO_03438 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KLOEOPPO_03439 2.3e-33 yyzM S protein conserved in bacteria
KLOEOPPO_03440 1.8e-176 yyaD S Membrane
KLOEOPPO_03441 2.8e-111 yyaC S Sporulation protein YyaC
KLOEOPPO_03442 2.1e-149 spo0J K Belongs to the ParB family
KLOEOPPO_03443 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
KLOEOPPO_03444 9.6e-74 S Bacterial PH domain
KLOEOPPO_03445 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KLOEOPPO_03446 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KLOEOPPO_03447 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KLOEOPPO_03448 1.2e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KLOEOPPO_03449 6.5e-108 jag S single-stranded nucleic acid binding R3H
KLOEOPPO_03450 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLOEOPPO_03451 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KLOEOPPO_03452 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KLOEOPPO_03453 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KLOEOPPO_03454 2.4e-33 yaaA S S4 domain
KLOEOPPO_03455 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KLOEOPPO_03456 1.8e-37 yaaB S Domain of unknown function (DUF370)
KLOEOPPO_03457 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLOEOPPO_03458 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLOEOPPO_03459 3.4e-39 S COG NOG14552 non supervised orthologous group
KLOEOPPO_03462 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KLOEOPPO_03464 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
KLOEOPPO_03465 2.2e-142 ybbA S Putative esterase
KLOEOPPO_03466 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_03467 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_03468 2.7e-166 feuA P Iron-uptake system-binding protein
KLOEOPPO_03469 2.9e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KLOEOPPO_03470 5.4e-239 ybbC 3.2.1.52 S protein conserved in bacteria
KLOEOPPO_03471 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KLOEOPPO_03472 1.1e-250 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KLOEOPPO_03473 3.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KLOEOPPO_03474 2.5e-150 ybbH K transcriptional
KLOEOPPO_03475 3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KLOEOPPO_03476 1.6e-85 ybbJ J acetyltransferase
KLOEOPPO_03477 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KLOEOPPO_03483 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KLOEOPPO_03484 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KLOEOPPO_03485 2.3e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KLOEOPPO_03486 4.4e-224 ybbR S protein conserved in bacteria
KLOEOPPO_03487 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLOEOPPO_03488 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KLOEOPPO_03489 8.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KLOEOPPO_03490 7.5e-120 adaA 3.2.2.21 K Transcriptional regulator
KLOEOPPO_03491 1.6e-99 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KLOEOPPO_03492 4.1e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KLOEOPPO_03493 0.0 ybcC S Belongs to the UPF0753 family
KLOEOPPO_03494 1.1e-92 can 4.2.1.1 P carbonic anhydrase
KLOEOPPO_03495 6.2e-45
KLOEOPPO_03496 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
KLOEOPPO_03497 5.1e-50 ybzH K Helix-turn-helix domain
KLOEOPPO_03498 2.6e-203 ybcL EGP Major facilitator Superfamily
KLOEOPPO_03500 9.1e-239 J 4Fe-4S single cluster domain
KLOEOPPO_03501 7.8e-277 V CAAX protease self-immunity
KLOEOPPO_03502 1.9e-135 skfE V ABC transporter
KLOEOPPO_03503 4e-248 skfF S ABC transporter
KLOEOPPO_03504 7.8e-91 C HEAT repeats
KLOEOPPO_03505 9.6e-79 txn CO Thioredoxin-like
KLOEOPPO_03506 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KLOEOPPO_03507 3.8e-122 T Transcriptional regulatory protein, C terminal
KLOEOPPO_03508 1.8e-168 T His Kinase A (phospho-acceptor) domain
KLOEOPPO_03510 3.9e-139 KLT Protein tyrosine kinase
KLOEOPPO_03511 1.7e-151 ybdN
KLOEOPPO_03512 1.5e-214 ybdO S Domain of unknown function (DUF4885)
KLOEOPPO_03513 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KLOEOPPO_03514 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
KLOEOPPO_03515 4.9e-30 ybxH S Family of unknown function (DUF5370)
KLOEOPPO_03516 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
KLOEOPPO_03517 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KLOEOPPO_03518 4.9e-41 ybyB
KLOEOPPO_03519 8.8e-290 ybeC E amino acid
KLOEOPPO_03520 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KLOEOPPO_03521 7.3e-258 glpT G -transporter
KLOEOPPO_03522 2.9e-35 S Protein of unknown function (DUF2651)
KLOEOPPO_03523 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
KLOEOPPO_03524 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
KLOEOPPO_03526 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
KLOEOPPO_03527 8.8e-162 ybfH EG EamA-like transporter family
KLOEOPPO_03528 9.7e-144 msmR K AraC-like ligand binding domain
KLOEOPPO_03529 2.3e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KLOEOPPO_03530 1.5e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KLOEOPPO_03532 2.1e-168 S Alpha/beta hydrolase family
KLOEOPPO_03533 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLOEOPPO_03534 2.7e-85 ybfM S SNARE associated Golgi protein
KLOEOPPO_03535 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KLOEOPPO_03536 4.6e-45 ybfN
KLOEOPPO_03537 3.2e-253 S Erythromycin esterase
KLOEOPPO_03538 6.7e-167 ybfP K Transcriptional regulator
KLOEOPPO_03539 3.9e-192 yceA S Belongs to the UPF0176 family
KLOEOPPO_03540 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KLOEOPPO_03541 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KLOEOPPO_03542 4.8e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KLOEOPPO_03543 4.9e-128 K UTRA
KLOEOPPO_03545 8.7e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KLOEOPPO_03546 4.1e-259 mmuP E amino acid
KLOEOPPO_03547 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KLOEOPPO_03548 5.6e-256 agcS E Sodium alanine symporter
KLOEOPPO_03549 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
KLOEOPPO_03550 2.1e-228 phoQ 2.7.13.3 T Histidine kinase
KLOEOPPO_03551 9e-170 glnL T Regulator
KLOEOPPO_03552 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
KLOEOPPO_03553 1.3e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KLOEOPPO_03554 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
KLOEOPPO_03555 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KLOEOPPO_03556 1.5e-124 ycbG K FCD
KLOEOPPO_03557 5.4e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
KLOEOPPO_03558 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
KLOEOPPO_03559 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KLOEOPPO_03560 7.3e-172 eamA1 EG spore germination
KLOEOPPO_03561 2.2e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_03562 7.6e-169 T PhoQ Sensor
KLOEOPPO_03563 4.8e-168 ycbN V ABC transporter, ATP-binding protein
KLOEOPPO_03564 2.1e-115 S ABC-2 family transporter protein
KLOEOPPO_03565 8.2e-53 ycbP S Protein of unknown function (DUF2512)
KLOEOPPO_03566 1.3e-78 sleB 3.5.1.28 M Cell wall
KLOEOPPO_03567 6.6e-136 ycbR T vWA found in TerF C terminus
KLOEOPPO_03568 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KLOEOPPO_03569 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KLOEOPPO_03570 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KLOEOPPO_03571 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KLOEOPPO_03572 5.2e-201 ycbU E Selenocysteine lyase
KLOEOPPO_03573 5.8e-229 lmrB EGP the major facilitator superfamily
KLOEOPPO_03574 1.6e-100 yxaF K Transcriptional regulator
KLOEOPPO_03575 1.8e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KLOEOPPO_03576 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KLOEOPPO_03577 2e-59 S RDD family
KLOEOPPO_03578 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
KLOEOPPO_03579 2e-161 2.7.13.3 T GHKL domain
KLOEOPPO_03580 4.9e-54 lytR_2 T LytTr DNA-binding domain
KLOEOPPO_03581 5.1e-61 lytR_2 T LytTr DNA-binding domain
KLOEOPPO_03582 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
KLOEOPPO_03583 4.5e-203 natB CP ABC-2 family transporter protein
KLOEOPPO_03584 4.6e-174 yccK C Aldo keto reductase
KLOEOPPO_03585 6.6e-177 ycdA S Domain of unknown function (DUF5105)
KLOEOPPO_03586 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KLOEOPPO_03587 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KLOEOPPO_03588 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
KLOEOPPO_03589 5.5e-174 S response regulator aspartate phosphatase
KLOEOPPO_03590 4.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
KLOEOPPO_03591 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KLOEOPPO_03592 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
KLOEOPPO_03593 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KLOEOPPO_03594 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KLOEOPPO_03595 4.2e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KLOEOPPO_03596 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KLOEOPPO_03597 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
KLOEOPPO_03598 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
KLOEOPPO_03599 1.4e-136 terC P Protein of unknown function (DUF475)
KLOEOPPO_03600 0.0 yceG S Putative component of 'biosynthetic module'
KLOEOPPO_03601 2e-192 yceH P Belongs to the TelA family
KLOEOPPO_03602 2.5e-217 naiP P Uncharacterised MFS-type transporter YbfB
KLOEOPPO_03603 1.7e-205 yceJ EGP Uncharacterised MFS-type transporter YbfB
KLOEOPPO_03604 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
KLOEOPPO_03605 2.5e-228 proV 3.6.3.32 E glycine betaine
KLOEOPPO_03606 1.3e-127 opuAB P glycine betaine
KLOEOPPO_03607 5.3e-164 opuAC E glycine betaine
KLOEOPPO_03608 7e-217 amhX S amidohydrolase
KLOEOPPO_03609 5.6e-256 ycgA S Membrane
KLOEOPPO_03610 1.2e-80 ycgB
KLOEOPPO_03611 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
KLOEOPPO_03612 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLOEOPPO_03613 3.3e-289 lctP C L-lactate permease
KLOEOPPO_03614 3.9e-263 mdr EGP Major facilitator Superfamily
KLOEOPPO_03615 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
KLOEOPPO_03616 6.8e-113 ycgF E Lysine exporter protein LysE YggA
KLOEOPPO_03617 1.2e-151 yqcI S YqcI/YcgG family
KLOEOPPO_03618 1.1e-248 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KLOEOPPO_03619 2.4e-112 ycgI S Domain of unknown function (DUF1989)
KLOEOPPO_03620 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KLOEOPPO_03621 4.7e-108 tmrB S AAA domain
KLOEOPPO_03623 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KLOEOPPO_03624 2e-143 yafE Q ubiE/COQ5 methyltransferase family
KLOEOPPO_03625 3e-176 oxyR3 K LysR substrate binding domain
KLOEOPPO_03626 3.6e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KLOEOPPO_03627 2.9e-145 ycgL S Predicted nucleotidyltransferase
KLOEOPPO_03628 5.1e-170 ycgM E Proline dehydrogenase
KLOEOPPO_03629 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KLOEOPPO_03630 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLOEOPPO_03631 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
KLOEOPPO_03632 1.3e-146 ycgQ S membrane
KLOEOPPO_03633 3.5e-139 ycgR S permeases
KLOEOPPO_03634 1.6e-157 I alpha/beta hydrolase fold
KLOEOPPO_03635 2.1e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KLOEOPPO_03636 7.9e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KLOEOPPO_03637 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
KLOEOPPO_03638 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KLOEOPPO_03639 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KLOEOPPO_03640 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KLOEOPPO_03641 3.8e-221 nasA P COG2223 Nitrate nitrite transporter
KLOEOPPO_03642 9.7e-169 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
KLOEOPPO_03643 6.8e-101 yciB M ErfK YbiS YcfS YnhG
KLOEOPPO_03644 1.4e-228 yciC S GTPases (G3E family)
KLOEOPPO_03645 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
KLOEOPPO_03646 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KLOEOPPO_03647 7.8e-52 yckD S Protein of unknown function (DUF2680)
KLOEOPPO_03648 2.8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KLOEOPPO_03649 6.5e-69 nin S Competence protein J (ComJ)
KLOEOPPO_03650 3e-70 nucA M Deoxyribonuclease NucA/NucB
KLOEOPPO_03651 3.9e-187 tlpC 2.7.13.3 NT chemotaxis protein
KLOEOPPO_03652 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KLOEOPPO_03653 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KLOEOPPO_03654 1.3e-63 hxlR K transcriptional
KLOEOPPO_03655 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_03656 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KLOEOPPO_03657 2.2e-139 srfAD Q thioesterase
KLOEOPPO_03658 1.5e-225 EGP Major Facilitator Superfamily
KLOEOPPO_03659 3e-88 S YcxB-like protein
KLOEOPPO_03660 1.2e-158 ycxC EG EamA-like transporter family
KLOEOPPO_03661 6.5e-159 ycxD K GntR family transcriptional regulator
KLOEOPPO_03662 2.6e-80 ycxD K GntR family transcriptional regulator
KLOEOPPO_03663 2.9e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KLOEOPPO_03664 1.7e-114 yczE S membrane
KLOEOPPO_03665 1.4e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KLOEOPPO_03666 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
KLOEOPPO_03667 3.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KLOEOPPO_03668 1.9e-161 bsdA K LysR substrate binding domain
KLOEOPPO_03669 7.6e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KLOEOPPO_03670 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KLOEOPPO_03671 4e-39 bsdD 4.1.1.61 S response to toxic substance
KLOEOPPO_03672 2.5e-80 yclD
KLOEOPPO_03673 5.1e-156 yclE 3.4.11.5 S Alpha beta hydrolase
KLOEOPPO_03674 9.2e-262 dtpT E amino acid peptide transporter
KLOEOPPO_03675 7e-309 yclG M Pectate lyase superfamily protein
KLOEOPPO_03677 6.8e-282 gerKA EG Spore germination protein
KLOEOPPO_03678 1.3e-232 gerKC S spore germination
KLOEOPPO_03679 9.9e-200 gerKB F Spore germination protein
KLOEOPPO_03680 1.5e-121 yclH P ABC transporter
KLOEOPPO_03681 7.6e-200 yclI V ABC transporter (permease) YclI
KLOEOPPO_03682 2.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLOEOPPO_03683 4.4e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KLOEOPPO_03684 2e-70 S aspartate phosphatase
KLOEOPPO_03688 8.3e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
KLOEOPPO_03689 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_03690 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_03691 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KLOEOPPO_03692 1.2e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KLOEOPPO_03693 3.2e-251 ycnB EGP Major facilitator Superfamily
KLOEOPPO_03694 2.7e-152 ycnC K Transcriptional regulator
KLOEOPPO_03695 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
KLOEOPPO_03696 1.6e-45 ycnE S Monooxygenase
KLOEOPPO_03697 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KLOEOPPO_03698 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KLOEOPPO_03699 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KLOEOPPO_03700 9.9e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KLOEOPPO_03701 6.1e-149 glcU U Glucose uptake
KLOEOPPO_03702 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_03703 1.3e-100 ycnI S protein conserved in bacteria
KLOEOPPO_03704 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
KLOEOPPO_03705 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KLOEOPPO_03706 7.3e-56
KLOEOPPO_03707 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KLOEOPPO_03708 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KLOEOPPO_03709 1.3e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KLOEOPPO_03710 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KLOEOPPO_03711 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KLOEOPPO_03712 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KLOEOPPO_03713 1.4e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
KLOEOPPO_03714 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KLOEOPPO_03716 3e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KLOEOPPO_03717 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
KLOEOPPO_03718 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KLOEOPPO_03719 1.7e-129 ycsI S Belongs to the D-glutamate cyclase family
KLOEOPPO_03720 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KLOEOPPO_03721 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KLOEOPPO_03722 1.2e-132 kipR K Transcriptional regulator
KLOEOPPO_03723 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
KLOEOPPO_03725 1.4e-49 yczJ S biosynthesis
KLOEOPPO_03726 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KLOEOPPO_03727 8.3e-173 ydhF S Oxidoreductase
KLOEOPPO_03728 0.0 mtlR K transcriptional regulator, MtlR
KLOEOPPO_03729 2.1e-293 ydaB IQ acyl-CoA ligase
KLOEOPPO_03730 1.5e-98 ydaC Q Methyltransferase domain
KLOEOPPO_03731 7e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_03732 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KLOEOPPO_03733 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KLOEOPPO_03734 6.8e-77 ydaG 1.4.3.5 S general stress protein
KLOEOPPO_03735 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KLOEOPPO_03736 3.3e-46 ydzA EGP Major facilitator Superfamily
KLOEOPPO_03737 2.5e-74 lrpC K Transcriptional regulator
KLOEOPPO_03738 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLOEOPPO_03739 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
KLOEOPPO_03740 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
KLOEOPPO_03741 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
KLOEOPPO_03742 4.5e-233 ydaM M Glycosyl transferase family group 2
KLOEOPPO_03743 0.0 ydaN S Bacterial cellulose synthase subunit
KLOEOPPO_03744 0.0 ydaO E amino acid
KLOEOPPO_03745 8.5e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KLOEOPPO_03746 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KLOEOPPO_03747 2.1e-39
KLOEOPPO_03748 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
KLOEOPPO_03750 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
KLOEOPPO_03751 2.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KLOEOPPO_03753 8.9e-59 ydbB G Cupin domain
KLOEOPPO_03754 3.1e-62 ydbC S Domain of unknown function (DUF4937
KLOEOPPO_03755 3.5e-154 ydbD P Catalase
KLOEOPPO_03756 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KLOEOPPO_03757 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KLOEOPPO_03758 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
KLOEOPPO_03759 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KLOEOPPO_03760 9.7e-181 ydbI S AI-2E family transporter
KLOEOPPO_03761 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
KLOEOPPO_03762 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KLOEOPPO_03763 1e-51 ydbL
KLOEOPPO_03764 1.4e-217 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KLOEOPPO_03765 1.1e-18 S Fur-regulated basic protein B
KLOEOPPO_03766 2.2e-07 S Fur-regulated basic protein A
KLOEOPPO_03767 9.6e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KLOEOPPO_03768 4.3e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KLOEOPPO_03769 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KLOEOPPO_03770 6.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KLOEOPPO_03771 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KLOEOPPO_03772 2.1e-82 ydbS S Bacterial PH domain
KLOEOPPO_03773 1.1e-259 ydbT S Membrane
KLOEOPPO_03774 2.2e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KLOEOPPO_03775 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KLOEOPPO_03776 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KLOEOPPO_03777 2.1e-221 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KLOEOPPO_03778 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KLOEOPPO_03779 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KLOEOPPO_03780 1.3e-143 rsbR T Positive regulator of sigma-B
KLOEOPPO_03781 5.2e-57 rsbS T antagonist
KLOEOPPO_03782 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KLOEOPPO_03783 7.1e-189 rsbU 3.1.3.3 KT phosphatase
KLOEOPPO_03784 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
KLOEOPPO_03785 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KLOEOPPO_03786 5.8e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KLOEOPPO_03787 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KLOEOPPO_03788 0.0 yhgF K COG2183 Transcriptional accessory protein
KLOEOPPO_03789 1.6e-84 ydcK S Belongs to the SprT family
KLOEOPPO_03797 1.1e-74 rimJ2 J Acetyltransferase (GNAT) domain
KLOEOPPO_03798 4.2e-44
KLOEOPPO_03799 4.8e-139 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KLOEOPPO_03800 3.4e-33 K Helix-turn-helix XRE-family like proteins
KLOEOPPO_03801 7.3e-40
KLOEOPPO_03802 3.8e-190 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KLOEOPPO_03803 8.7e-30 cspL K Cold shock
KLOEOPPO_03804 2.3e-78 carD K Transcription factor
KLOEOPPO_03805 3.3e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KLOEOPPO_03806 9e-164 rhaS5 K AraC-like ligand binding domain
KLOEOPPO_03807 3.4e-172 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KLOEOPPO_03808 2.6e-163 ydeE K AraC family transcriptional regulator
KLOEOPPO_03809 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KLOEOPPO_03810 1.8e-216 ydeG EGP Major facilitator superfamily
KLOEOPPO_03811 2.3e-44 ydeH
KLOEOPPO_03812 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
KLOEOPPO_03813 1.3e-103
KLOEOPPO_03814 1.1e-31 S SNARE associated Golgi protein
KLOEOPPO_03815 1.8e-14 ptsH G PTS HPr component phosphorylation site
KLOEOPPO_03816 8.8e-85 K Transcriptional regulator C-terminal region
KLOEOPPO_03817 1.8e-153 ydeK EG -transporter
KLOEOPPO_03818 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KLOEOPPO_03819 4.2e-74 maoC I N-terminal half of MaoC dehydratase
KLOEOPPO_03820 8.6e-107 ydeN S Serine hydrolase
KLOEOPPO_03821 1.1e-58 K HxlR-like helix-turn-helix
KLOEOPPO_03822 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KLOEOPPO_03823 1.1e-191 ydeR EGP Major facilitator Superfamily
KLOEOPPO_03824 2.1e-103 ydeS K Transcriptional regulator
KLOEOPPO_03825 6.3e-57 arsR K transcriptional
KLOEOPPO_03826 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KLOEOPPO_03827 8.8e-147 ydfB J GNAT acetyltransferase
KLOEOPPO_03828 8.8e-162 ydfC EG EamA-like transporter family
KLOEOPPO_03829 1.5e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KLOEOPPO_03830 9.3e-115 ydfE S Flavin reductase like domain
KLOEOPPO_03831 1e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
KLOEOPPO_03832 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KLOEOPPO_03834 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
KLOEOPPO_03835 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLOEOPPO_03836 0.0 ydfJ S drug exporters of the RND superfamily
KLOEOPPO_03837 8.9e-175 S Alpha/beta hydrolase family
KLOEOPPO_03838 9.3e-116 S Protein of unknown function (DUF554)
KLOEOPPO_03839 6.6e-145 K Bacterial transcription activator, effector binding domain
KLOEOPPO_03840 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KLOEOPPO_03841 9.6e-112 ydfN C nitroreductase
KLOEOPPO_03842 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
KLOEOPPO_03843 8.8e-63 mhqP S DoxX
KLOEOPPO_03844 1.3e-57 traF CO Thioredoxin
KLOEOPPO_03845 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
KLOEOPPO_03846 6.3e-29
KLOEOPPO_03848 4.4e-118 ydfR S Protein of unknown function (DUF421)
KLOEOPPO_03849 5.2e-122 ydfS S Protein of unknown function (DUF421)
KLOEOPPO_03850 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
KLOEOPPO_03851 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
KLOEOPPO_03852 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
KLOEOPPO_03853 2.8e-100 K Bacterial regulatory proteins, tetR family
KLOEOPPO_03854 9.6e-53 S DoxX-like family
KLOEOPPO_03855 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
KLOEOPPO_03856 3e-298 expZ S ABC transporter
KLOEOPPO_03857 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KLOEOPPO_03858 3e-90 dinB S DinB family
KLOEOPPO_03859 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
KLOEOPPO_03860 0.0 ydgH S drug exporters of the RND superfamily
KLOEOPPO_03861 1.2e-112 drgA C nitroreductase
KLOEOPPO_03862 7.1e-69 ydgJ K Winged helix DNA-binding domain
KLOEOPPO_03863 7.4e-209 tcaB EGP Major facilitator Superfamily
KLOEOPPO_03864 1.2e-121 ydhB S membrane transporter protein
KLOEOPPO_03865 6.5e-122 ydhC K FCD
KLOEOPPO_03866 1.6e-243 ydhD M Glycosyl hydrolase
KLOEOPPO_03867 7.7e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KLOEOPPO_03868 1.6e-123
KLOEOPPO_03869 5.2e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KLOEOPPO_03870 4.6e-69 frataxin S Domain of unknown function (DU1801)
KLOEOPPO_03872 4.1e-86 K Acetyltransferase (GNAT) domain
KLOEOPPO_03873 2.5e-183 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLOEOPPO_03874 2.8e-97 ydhK M Protein of unknown function (DUF1541)
KLOEOPPO_03875 4.6e-200 pbuE EGP Major facilitator Superfamily
KLOEOPPO_03876 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KLOEOPPO_03877 8.7e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KLOEOPPO_03878 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLOEOPPO_03879 2.5e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KLOEOPPO_03880 3.9e-133 ydhQ K UTRA
KLOEOPPO_03881 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KLOEOPPO_03882 1.5e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
KLOEOPPO_03883 8.4e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KLOEOPPO_03884 3.9e-156 ydhU P Catalase
KLOEOPPO_03887 7.8e-08
KLOEOPPO_03889 4.9e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KLOEOPPO_03890 7.7e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KLOEOPPO_03891 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KLOEOPPO_03892 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KLOEOPPO_03893 2e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KLOEOPPO_03894 0.0 ydiF S ABC transporter
KLOEOPPO_03895 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KLOEOPPO_03896 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KLOEOPPO_03897 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KLOEOPPO_03898 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KLOEOPPO_03899 2.9e-27 ydiK S Domain of unknown function (DUF4305)
KLOEOPPO_03900 7.9e-129 ydiL S CAAX protease self-immunity
KLOEOPPO_03901 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLOEOPPO_03902 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KLOEOPPO_03903 6e-153 ydjC S Abhydrolase domain containing 18
KLOEOPPO_03904 0.0 K NB-ARC domain
KLOEOPPO_03905 8.5e-201 gutB 1.1.1.14 E Dehydrogenase
KLOEOPPO_03906 3.9e-254 gutA G MFS/sugar transport protein
KLOEOPPO_03907 7.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KLOEOPPO_03908 5.6e-113 pspA KT Phage shock protein A
KLOEOPPO_03909 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KLOEOPPO_03910 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KLOEOPPO_03911 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
KLOEOPPO_03912 4.7e-196 S Ion transport 2 domain protein
KLOEOPPO_03913 2.7e-258 iolT EGP Major facilitator Superfamily
KLOEOPPO_03914 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KLOEOPPO_03915 4.5e-64 ydjM M Lytic transglycolase
KLOEOPPO_03916 3.6e-151 ydjN U Involved in the tonB-independent uptake of proteins
KLOEOPPO_03918 1.4e-34 ydjO S Cold-inducible protein YdjO
KLOEOPPO_03919 2.8e-159 ydjP I Alpha/beta hydrolase family
KLOEOPPO_03920 1.6e-177 yeaA S Protein of unknown function (DUF4003)
KLOEOPPO_03921 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KLOEOPPO_03922 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KLOEOPPO_03923 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KLOEOPPO_03924 3e-176 yeaC S COG0714 MoxR-like ATPases
KLOEOPPO_03925 3.6e-224 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KLOEOPPO_03926 0.0 yebA E COG1305 Transglutaminase-like enzymes
KLOEOPPO_03927 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KLOEOPPO_03928 7.8e-212 pbuG S permease
KLOEOPPO_03929 6.8e-118 yebC M Membrane
KLOEOPPO_03931 8.9e-93 yebE S UPF0316 protein
KLOEOPPO_03932 8e-28 yebG S NETI protein
KLOEOPPO_03933 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KLOEOPPO_03934 1.9e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KLOEOPPO_03935 1.3e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KLOEOPPO_03936 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KLOEOPPO_03937 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLOEOPPO_03938 1.9e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLOEOPPO_03939 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLOEOPPO_03940 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KLOEOPPO_03941 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KLOEOPPO_03942 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KLOEOPPO_03943 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KLOEOPPO_03944 3.8e-232 purD 6.3.4.13 F Belongs to the GARS family
KLOEOPPO_03945 8.1e-70 K helix_turn_helix ASNC type
KLOEOPPO_03946 1.9e-231 yjeH E Amino acid permease
KLOEOPPO_03947 2.7e-27 S Protein of unknown function (DUF2892)
KLOEOPPO_03948 0.0 yerA 3.5.4.2 F adenine deaminase
KLOEOPPO_03949 1.7e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
KLOEOPPO_03950 4.8e-51 yerC S protein conserved in bacteria
KLOEOPPO_03951 1.5e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KLOEOPPO_03952 1.1e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KLOEOPPO_03953 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KLOEOPPO_03954 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KLOEOPPO_03955 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
KLOEOPPO_03956 9.2e-197 yerI S homoserine kinase type II (protein kinase fold)
KLOEOPPO_03957 9.4e-124 sapB S MgtC SapB transporter
KLOEOPPO_03958 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLOEOPPO_03959 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLOEOPPO_03960 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KLOEOPPO_03961 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLOEOPPO_03962 5.1e-148 yerO K Transcriptional regulator
KLOEOPPO_03963 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KLOEOPPO_03964 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KLOEOPPO_03965 1e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLOEOPPO_03966 3e-151 2.1.1.37 L C-5 cytosine-specific DNA methylase
KLOEOPPO_03967 2.8e-143 3.1.21.4 S type ii restriction enzyme
KLOEOPPO_03969 1.8e-37
KLOEOPPO_03970 1.1e-157 L nucleic acid phosphodiester bond hydrolysis
KLOEOPPO_03971 4.5e-122 3.4.24.40 CO amine dehydrogenase activity
KLOEOPPO_03972 1.4e-53
KLOEOPPO_03973 1.8e-50
KLOEOPPO_03974 4.8e-210 S Tetratricopeptide repeat
KLOEOPPO_03976 2.7e-126 yeeN K transcriptional regulatory protein
KLOEOPPO_03978 1.1e-101 dhaR3 K Transcriptional regulator
KLOEOPPO_03979 1.8e-80 yesE S SnoaL-like domain
KLOEOPPO_03980 4.9e-151 yesF GM NAD(P)H-binding
KLOEOPPO_03981 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
KLOEOPPO_03982 1.5e-45 cotJB S CotJB protein
KLOEOPPO_03983 5.2e-104 cotJC P Spore Coat
KLOEOPPO_03984 3e-101 yesJ K Acetyltransferase (GNAT) family
KLOEOPPO_03985 9.2e-102 yesL S Protein of unknown function, DUF624
KLOEOPPO_03986 0.0 yesM 2.7.13.3 T Histidine kinase
KLOEOPPO_03987 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
KLOEOPPO_03988 8e-246 yesO G Bacterial extracellular solute-binding protein
KLOEOPPO_03989 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
KLOEOPPO_03990 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
KLOEOPPO_03991 2.3e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
KLOEOPPO_03992 0.0 yesS K Transcriptional regulator
KLOEOPPO_03993 1.3e-128 E GDSL-like Lipase/Acylhydrolase
KLOEOPPO_03994 6e-128 yesU S Domain of unknown function (DUF1961)
KLOEOPPO_03995 9.7e-112 yesV S Protein of unknown function, DUF624
KLOEOPPO_03996 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KLOEOPPO_03997 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KLOEOPPO_03999 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
KLOEOPPO_04000 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
KLOEOPPO_04001 0.0 yetA
KLOEOPPO_04002 9.6e-291 lplA G Bacterial extracellular solute-binding protein
KLOEOPPO_04003 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KLOEOPPO_04004 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
KLOEOPPO_04005 2.4e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KLOEOPPO_04006 8.8e-122 yetF S membrane
KLOEOPPO_04007 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KLOEOPPO_04008 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLOEOPPO_04009 2.2e-34
KLOEOPPO_04010 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KLOEOPPO_04011 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
KLOEOPPO_04012 5.3e-105 yetJ S Belongs to the BI1 family
KLOEOPPO_04013 5.4e-159 yetK EG EamA-like transporter family
KLOEOPPO_04014 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
KLOEOPPO_04015 2.2e-207 yetM CH FAD binding domain
KLOEOPPO_04016 3.6e-199 yetN S Protein of unknown function (DUF3900)
KLOEOPPO_04017 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KLOEOPPO_04018 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KLOEOPPO_04019 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
KLOEOPPO_04020 1.9e-172 yfnG 4.2.1.45 M dehydratase
KLOEOPPO_04021 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
KLOEOPPO_04022 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KLOEOPPO_04023 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
KLOEOPPO_04024 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
KLOEOPPO_04025 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KLOEOPPO_04026 8.4e-241 yfnA E amino acid
KLOEOPPO_04027 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KLOEOPPO_04028 1.1e-113 yfmS NT chemotaxis protein
KLOEOPPO_04029 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KLOEOPPO_04030 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
KLOEOPPO_04031 2.8e-70 yfmP K transcriptional
KLOEOPPO_04032 4.3e-209 yfmO EGP Major facilitator Superfamily
KLOEOPPO_04033 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KLOEOPPO_04034 2.9e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KLOEOPPO_04035 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
KLOEOPPO_04036 9.4e-189 yfmJ S N-terminal domain of oxidoreductase
KLOEOPPO_04037 7.7e-214 G Major Facilitator Superfamily
KLOEOPPO_04038 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
KLOEOPPO_04039 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
KLOEOPPO_04040 2e-167 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_04041 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_04042 6.1e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KLOEOPPO_04043 8.5e-24 S Protein of unknown function (DUF3212)
KLOEOPPO_04044 7.6e-58 yflT S Heat induced stress protein YflT
KLOEOPPO_04045 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KLOEOPPO_04046 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
KLOEOPPO_04047 2.2e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KLOEOPPO_04048 8.9e-119 citT T response regulator
KLOEOPPO_04049 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
KLOEOPPO_04050 1.9e-226 citM C Citrate transporter
KLOEOPPO_04051 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KLOEOPPO_04052 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KLOEOPPO_04053 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KLOEOPPO_04054 9.9e-123 yflK S protein conserved in bacteria
KLOEOPPO_04055 4e-18 yflJ S Protein of unknown function (DUF2639)
KLOEOPPO_04056 1.6e-18 yflI
KLOEOPPO_04057 2.4e-50 yflH S Protein of unknown function (DUF3243)
KLOEOPPO_04058 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
KLOEOPPO_04059 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KLOEOPPO_04060 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KLOEOPPO_04061 6e-67 yhdN S Domain of unknown function (DUF1992)
KLOEOPPO_04062 3.1e-251 agcS_1 E Sodium alanine symporter
KLOEOPPO_04063 1.3e-193 E Spore germination protein
KLOEOPPO_04065 5.1e-207 yfkR S spore germination
KLOEOPPO_04066 3.2e-234 yfkQ EG Spore germination protein
KLOEOPPO_04067 6.5e-27 yfkQ EG Spore germination protein
KLOEOPPO_04068 2.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KLOEOPPO_04069 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KLOEOPPO_04070 3.9e-133 treR K transcriptional
KLOEOPPO_04071 1.1e-124 yfkO C nitroreductase
KLOEOPPO_04072 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KLOEOPPO_04073 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
KLOEOPPO_04074 7.5e-206 ydiM EGP Major facilitator Superfamily
KLOEOPPO_04075 3.5e-29 yfkK S Belongs to the UPF0435 family
KLOEOPPO_04076 1e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLOEOPPO_04077 2.4e-50 yfkI S gas vesicle protein
KLOEOPPO_04078 8.2e-143 yihY S Belongs to the UPF0761 family
KLOEOPPO_04079 5e-08
KLOEOPPO_04080 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KLOEOPPO_04081 1.8e-182 cax P COG0387 Ca2 H antiporter
KLOEOPPO_04082 1.2e-146 yfkD S YfkD-like protein
KLOEOPPO_04083 6.6e-148 yfkC M Mechanosensitive ion channel
KLOEOPPO_04084 5.4e-222 yfkA S YfkB-like domain
KLOEOPPO_04085 1.1e-26 yfjT
KLOEOPPO_04086 1.7e-153 pdaA G deacetylase
KLOEOPPO_04087 1.8e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KLOEOPPO_04088 1.7e-184 corA P Mediates influx of magnesium ions
KLOEOPPO_04089 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KLOEOPPO_04090 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLOEOPPO_04091 5.1e-44 S YfzA-like protein
KLOEOPPO_04092 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLOEOPPO_04093 1.1e-83 yfjM S Psort location Cytoplasmic, score
KLOEOPPO_04094 3e-29 yfjL
KLOEOPPO_04095 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KLOEOPPO_04096 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KLOEOPPO_04097 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KLOEOPPO_04098 2.4e-256 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KLOEOPPO_04099 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KLOEOPPO_04100 1.2e-25 sspH S Belongs to the SspH family
KLOEOPPO_04101 4e-56 yfjF S UPF0060 membrane protein
KLOEOPPO_04102 1.4e-79 S Family of unknown function (DUF5381)
KLOEOPPO_04103 5.3e-101 yfjD S Family of unknown function (DUF5381)
KLOEOPPO_04104 4.1e-144 yfjC
KLOEOPPO_04105 3.9e-189 yfjB
KLOEOPPO_04106 1.1e-44 yfjA S Belongs to the WXG100 family
KLOEOPPO_04107 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KLOEOPPO_04108 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
KLOEOPPO_04109 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KLOEOPPO_04110 2.1e-310 yfiB3 V ABC transporter
KLOEOPPO_04111 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KLOEOPPO_04112 9.8e-65 mhqP S DoxX
KLOEOPPO_04113 5.7e-163 yfiE 1.13.11.2 S glyoxalase
KLOEOPPO_04114 1.5e-177 K AraC-like ligand binding domain
KLOEOPPO_04115 5.3e-262 iolT EGP Major facilitator Superfamily
KLOEOPPO_04116 8.4e-184 G Xylose isomerase
KLOEOPPO_04117 1.1e-233 S Oxidoreductase
KLOEOPPO_04119 1.1e-214 yxjM T Histidine kinase
KLOEOPPO_04120 3.2e-113 KT LuxR family transcriptional regulator
KLOEOPPO_04121 5.2e-170 V ABC transporter, ATP-binding protein
KLOEOPPO_04122 1.7e-205 V ABC-2 family transporter protein
KLOEOPPO_04123 3.8e-202 V COG0842 ABC-type multidrug transport system, permease component
KLOEOPPO_04124 8.3e-99 padR K transcriptional
KLOEOPPO_04125 1.7e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KLOEOPPO_04126 8.4e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KLOEOPPO_04127 2e-109 yfiR K Transcriptional regulator
KLOEOPPO_04128 5.1e-221 yfiS EGP Major facilitator Superfamily
KLOEOPPO_04129 1.2e-99 yfiT S Belongs to the metal hydrolase YfiT family
KLOEOPPO_04130 8.7e-287 yfiU EGP Major facilitator Superfamily
KLOEOPPO_04131 3.1e-81 yfiV K transcriptional
KLOEOPPO_04132 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLOEOPPO_04133 6.2e-182 yfiY P ABC transporter substrate-binding protein
KLOEOPPO_04134 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_04135 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KLOEOPPO_04136 1.3e-165 yfhB 5.3.3.17 S PhzF family
KLOEOPPO_04137 1.5e-106 yfhC C nitroreductase
KLOEOPPO_04138 2.1e-25 yfhD S YfhD-like protein
KLOEOPPO_04140 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
KLOEOPPO_04141 9.7e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
KLOEOPPO_04142 2.2e-51 yfhH S Protein of unknown function (DUF1811)
KLOEOPPO_04143 3.3e-209 yfhI EGP Major facilitator Superfamily
KLOEOPPO_04144 6.2e-20 sspK S reproduction
KLOEOPPO_04145 1.3e-44 yfhJ S WVELL protein
KLOEOPPO_04146 1e-90 batE T Bacterial SH3 domain homologues
KLOEOPPO_04147 6.6e-50 yfhL S SdpI/YhfL protein family
KLOEOPPO_04148 2.8e-170 yfhM S Alpha beta hydrolase
KLOEOPPO_04149 1.4e-184 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KLOEOPPO_04150 0.0 yfhO S Bacterial membrane protein YfhO
KLOEOPPO_04151 5.5e-186 yfhP S membrane-bound metal-dependent
KLOEOPPO_04152 7.8e-212 mutY L A G-specific
KLOEOPPO_04153 6.9e-36 yfhS
KLOEOPPO_04154 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KLOEOPPO_04155 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
KLOEOPPO_04156 4.9e-48 ygaB S YgaB-like protein
KLOEOPPO_04157 1.3e-104 ygaC J Belongs to the UPF0374 family
KLOEOPPO_04158 9.1e-301 ygaD V ABC transporter
KLOEOPPO_04159 8.7e-180 ygaE S Membrane
KLOEOPPO_04160 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KLOEOPPO_04161 6.9e-86 bcp 1.11.1.15 O Peroxiredoxin
KLOEOPPO_04162 4e-80 perR P Belongs to the Fur family
KLOEOPPO_04163 9.5e-56 ygzB S UPF0295 protein
KLOEOPPO_04164 6.7e-167 ygxA S Nucleotidyltransferase-like
KLOEOPPO_04165 2.9e-76 ctsR K Belongs to the CtsR family
KLOEOPPO_04166 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KLOEOPPO_04167 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KLOEOPPO_04168 0.0 clpC O Belongs to the ClpA ClpB family
KLOEOPPO_04169 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLOEOPPO_04170 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KLOEOPPO_04171 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KLOEOPPO_04172 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KLOEOPPO_04173 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KLOEOPPO_04174 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLOEOPPO_04175 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
KLOEOPPO_04176 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLOEOPPO_04177 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KLOEOPPO_04178 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLOEOPPO_04179 1.2e-88 yacP S RNA-binding protein containing a PIN domain
KLOEOPPO_04180 4.4e-115 sigH K Belongs to the sigma-70 factor family
KLOEOPPO_04181 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KLOEOPPO_04182 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
KLOEOPPO_04183 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KLOEOPPO_04184 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KLOEOPPO_04185 8.7e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KLOEOPPO_04186 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KLOEOPPO_04187 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
KLOEOPPO_04188 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLOEOPPO_04189 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLOEOPPO_04190 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KLOEOPPO_04191 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KLOEOPPO_04192 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KLOEOPPO_04193 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLOEOPPO_04194 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLOEOPPO_04195 2.6e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KLOEOPPO_04196 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KLOEOPPO_04197 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLOEOPPO_04198 6.7e-105 rplD J Forms part of the polypeptide exit tunnel
KLOEOPPO_04199 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KLOEOPPO_04200 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KLOEOPPO_04201 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLOEOPPO_04202 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KLOEOPPO_04203 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KLOEOPPO_04204 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KLOEOPPO_04205 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KLOEOPPO_04206 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KLOEOPPO_04207 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KLOEOPPO_04208 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KLOEOPPO_04209 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KLOEOPPO_04210 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLOEOPPO_04211 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KLOEOPPO_04212 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLOEOPPO_04213 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KLOEOPPO_04214 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KLOEOPPO_04215 1.9e-23 rpmD J Ribosomal protein L30
KLOEOPPO_04216 1.8e-72 rplO J binds to the 23S rRNA
KLOEOPPO_04217 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KLOEOPPO_04218 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KLOEOPPO_04219 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
KLOEOPPO_04220 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KLOEOPPO_04221 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KLOEOPPO_04222 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KLOEOPPO_04223 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KLOEOPPO_04224 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLOEOPPO_04225 3.6e-58 rplQ J Ribosomal protein L17
KLOEOPPO_04226 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLOEOPPO_04227 2.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLOEOPPO_04228 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLOEOPPO_04229 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KLOEOPPO_04230 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KLOEOPPO_04231 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KLOEOPPO_04232 5.3e-144 ybaJ Q Methyltransferase domain
KLOEOPPO_04233 9.7e-66 ybaK S Protein of unknown function (DUF2521)
KLOEOPPO_04234 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KLOEOPPO_04235 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KLOEOPPO_04236 1.2e-84 gerD
KLOEOPPO_04237 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KLOEOPPO_04238 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
KLOEOPPO_04239 3.4e-39 S COG NOG14552 non supervised orthologous group
KLOEOPPO_04240 8e-139 L Transposase IS66 family
KLOEOPPO_04241 1e-20 umuD 3.4.21.88 KT Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KLOEOPPO_04242 1.7e-40
KLOEOPPO_04243 4.5e-238 L Transposase
KLOEOPPO_04244 7.3e-118 L resolvase
KLOEOPPO_04245 4.8e-117 D plasmid maintenance
KLOEOPPO_04246 3.6e-45
KLOEOPPO_04249 1.3e-57
KLOEOPPO_04250 1.5e-79
KLOEOPPO_04251 4.9e-154 L Initiator Replication protein
KLOEOPPO_04252 1.5e-94 O DnaJ molecular chaperone homology domain
KLOEOPPO_04254 2.3e-101
KLOEOPPO_04256 5.2e-37
KLOEOPPO_04260 8.2e-99
KLOEOPPO_04261 7.1e-217 U Relaxase/Mobilisation nuclease domain
KLOEOPPO_04262 3.9e-18 nusG K Participates in transcription elongation, termination and antitermination
KLOEOPPO_04264 4.9e-119 virB1 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KLOEOPPO_04265 5.3e-44
KLOEOPPO_04266 0.0 virB4 U type IV secretory pathway, VirB4 components
KLOEOPPO_04267 7.2e-117 virB5 U type IV secretion
KLOEOPPO_04268 2.1e-12
KLOEOPPO_04269 1.6e-191 virB6 U Conjugal transfer protein
KLOEOPPO_04270 2.9e-131 virB8 U VirB8 protein
KLOEOPPO_04271 4e-167 virB9 U Type IV secretory pathway, VirB9 components
KLOEOPPO_04272 2.4e-207 virB10 U Conjugal transfer protein
KLOEOPPO_04274 1.8e-203 virB11 NU COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis
KLOEOPPO_04275 0.0 virD4 U Type IV secretory pathway, VirD4 components
KLOEOPPO_04276 6.7e-34 S Cag pathogenicity island protein Cag12
KLOEOPPO_04277 7.9e-54 S TrbM
KLOEOPPO_04279 9.1e-89 3.1.31.1 L nuclease
KLOEOPPO_04280 3.1e-242 3.4.21.53 O protein catabolic process
KLOEOPPO_04281 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLOEOPPO_04282 1.4e-64 S Domain in histone-like proteins of HNS family
KLOEOPPO_04283 2.5e-22 S metal cluster binding
KLOEOPPO_04285 9.6e-74 S SprT-like family
KLOEOPPO_04286 0.0 L Transposase
KLOEOPPO_04287 1.2e-106 L Resolvase
KLOEOPPO_04288 3.6e-162 fghA 3.1.2.12 CE1 S Serine hydrolase involved in the detoxification of formaldehyde
KLOEOPPO_04289 4.5e-70 E Glyoxalase-like domain
KLOEOPPO_04290 3.4e-216 adhC 1.1.1.1, 1.1.1.284 C Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily
KLOEOPPO_04291 1.8e-41 frmR S protein conserved in bacteria
KLOEOPPO_04297 7.8e-235 L Transposase
KLOEOPPO_04298 1.6e-94 L Transposase
KLOEOPPO_04299 0.0 L COG4644 Transposase and inactivated derivatives, TnpA family
KLOEOPPO_04300 9.4e-75 ccrA 3.5.2.6 S Metallo-beta-lactamase superfamily
KLOEOPPO_04301 1.2e-26 ble E lactoylglutathione lyase activity
KLOEOPPO_04302 2.2e-74 trpF 4.1.1.48, 5.3.1.24 E Belongs to the TrpF family
KLOEOPPO_04303 3.5e-82 S Oxidoreductase family, NAD-binding Rossmann fold
KLOEOPPO_04304 8.1e-31 cutA 4.2.3.1 P protein involved in tolerance to divalent cations
KLOEOPPO_04305 9e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLOEOPPO_04306 5.2e-274 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KLOEOPPO_04307 8.1e-261 M Transposase
KLOEOPPO_04308 8e-139 L Transposase IS66 family
KLOEOPPO_04309 3.4e-31 csfB S Inhibitor of sigma-G Gin
KLOEOPPO_04310 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KLOEOPPO_04311 9.9e-203 yaaN P Belongs to the TelA family
KLOEOPPO_04312 5.1e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KLOEOPPO_04313 6.9e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLOEOPPO_04314 2.2e-54 yaaQ S protein conserved in bacteria
KLOEOPPO_04315 1.5e-71 yaaR S protein conserved in bacteria
KLOEOPPO_04316 2.2e-182 holB 2.7.7.7 L DNA polymerase III
KLOEOPPO_04317 2.1e-146 yaaT S stage 0 sporulation protein
KLOEOPPO_04318 4.8e-31 yabA L Involved in initiation control of chromosome replication
KLOEOPPO_04319 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
KLOEOPPO_04320 1.5e-49 yazA L endonuclease containing a URI domain
KLOEOPPO_04321 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KLOEOPPO_04322 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KLOEOPPO_04323 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLOEOPPO_04324 3.4e-143 tatD L hydrolase, TatD
KLOEOPPO_04325 2e-167 rpfB GH23 T protein conserved in bacteria
KLOEOPPO_04326 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KLOEOPPO_04327 3.4e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KLOEOPPO_04328 1.8e-135 yabG S peptidase
KLOEOPPO_04329 7.8e-39 veg S protein conserved in bacteria
KLOEOPPO_04330 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KLOEOPPO_04331 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KLOEOPPO_04332 1.1e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KLOEOPPO_04333 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KLOEOPPO_04334 7.3e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KLOEOPPO_04335 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLOEOPPO_04336 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KLOEOPPO_04337 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KLOEOPPO_04338 2.4e-39 yabK S Peptide ABC transporter permease
KLOEOPPO_04339 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KLOEOPPO_04340 1.5e-92 spoVT K stage V sporulation protein
KLOEOPPO_04341 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KLOEOPPO_04342 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KLOEOPPO_04343 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KLOEOPPO_04344 1.5e-49 yabP S Sporulation protein YabP
KLOEOPPO_04345 4.3e-107 yabQ S spore cortex biosynthesis protein
KLOEOPPO_04346 1.1e-44 divIC D Septum formation initiator
KLOEOPPO_04347 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KLOEOPPO_04350 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KLOEOPPO_04351 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
KLOEOPPO_04352 1.1e-184 KLT serine threonine protein kinase
KLOEOPPO_04353 6.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KLOEOPPO_04354 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLOEOPPO_04355 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLOEOPPO_04356 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KLOEOPPO_04357 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KLOEOPPO_04358 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KLOEOPPO_04359 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KLOEOPPO_04360 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KLOEOPPO_04361 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KLOEOPPO_04362 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KLOEOPPO_04363 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KLOEOPPO_04364 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KLOEOPPO_04365 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KLOEOPPO_04366 4.1e-30 yazB K transcriptional
KLOEOPPO_04367 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLOEOPPO_04368 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KLOEOPPO_04369 3.4e-39 S COG NOG14552 non supervised orthologous group
KLOEOPPO_04370 1e-181 yaaC S YaaC-like Protein
KLOEOPPO_04371 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KLOEOPPO_04372 9.8e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLOEOPPO_04373 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KLOEOPPO_04374 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KLOEOPPO_04375 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KLOEOPPO_04376 1.3e-09
KLOEOPPO_04377 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KLOEOPPO_04378 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KLOEOPPO_04379 1.2e-212 yaaH M Glycoside Hydrolase Family
KLOEOPPO_04380 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
KLOEOPPO_04381 4.3e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KLOEOPPO_04382 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLOEOPPO_04383 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KLOEOPPO_04384 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KLOEOPPO_04385 7.9e-32 yaaL S Protein of unknown function (DUF2508)
KLOEOPPO_04386 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
KLOEOPPO_04387 5.8e-39 S COG NOG14552 non supervised orthologous group
KLOEOPPO_04388 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_04389 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_04390 8.3e-96 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_04391 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_04392 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_04393 1.1e-89 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLOEOPPO_04394 3.4e-155 penP 3.5.2.6 V Beta-lactamase
KLOEOPPO_04395 2.4e-133 lacR K DeoR C terminal sensor domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)