ORF_ID e_value Gene_name EC_number CAZy COGs Description
LEHADEAE_00001 3.4e-39 S COG NOG14552 non supervised orthologous group
LEHADEAE_00002 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LEHADEAE_00003 1.7e-187 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEHADEAE_00004 4.5e-29 yazB K transcriptional
LEHADEAE_00005 2.4e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LEHADEAE_00006 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LEHADEAE_00007 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LEHADEAE_00008 2.5e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
LEHADEAE_00009 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
LEHADEAE_00010 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LEHADEAE_00011 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LEHADEAE_00012 3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
LEHADEAE_00013 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LEHADEAE_00014 3.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LEHADEAE_00015 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LEHADEAE_00016 1.5e-92 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LEHADEAE_00017 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LEHADEAE_00018 1.4e-184 KLT serine threonine protein kinase
LEHADEAE_00019 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
LEHADEAE_00020 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
LEHADEAE_00023 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
LEHADEAE_00024 4.1e-57 divIC D Septum formation initiator
LEHADEAE_00025 2.9e-103 yabQ S spore cortex biosynthesis protein
LEHADEAE_00026 1.9e-49 yabP S Sporulation protein YabP
LEHADEAE_00027 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LEHADEAE_00028 1.8e-273 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LEHADEAE_00029 5e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEHADEAE_00030 6.2e-91 spoVT K stage V sporulation protein
LEHADEAE_00031 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LEHADEAE_00032 3.7e-40 yabK S Peptide ABC transporter permease
LEHADEAE_00033 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LEHADEAE_00034 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LEHADEAE_00035 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LEHADEAE_00036 2e-247 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LEHADEAE_00037 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LEHADEAE_00038 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
LEHADEAE_00039 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LEHADEAE_00040 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LEHADEAE_00041 2.9e-27 sspF S DNA topological change
LEHADEAE_00042 7.8e-39 veg S protein conserved in bacteria
LEHADEAE_00043 8.4e-146 yabG S peptidase
LEHADEAE_00044 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LEHADEAE_00045 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LEHADEAE_00046 2.7e-231 rpfB GH23 T protein conserved in bacteria
LEHADEAE_00047 4.5e-143 tatD L hydrolase, TatD
LEHADEAE_00048 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LEHADEAE_00049 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
LEHADEAE_00050 3.2e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LEHADEAE_00051 5.2e-47 yazA L endonuclease containing a URI domain
LEHADEAE_00052 2.1e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
LEHADEAE_00053 7.7e-37 yabA L Involved in initiation control of chromosome replication
LEHADEAE_00054 8.8e-145 yaaT S stage 0 sporulation protein
LEHADEAE_00055 1.3e-182 holB 2.7.7.7 L DNA polymerase III
LEHADEAE_00056 1.2e-71 yaaR S protein conserved in bacteria
LEHADEAE_00057 7.5e-55 yaaQ S protein conserved in bacteria
LEHADEAE_00058 7.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LEHADEAE_00059 1.4e-267 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
LEHADEAE_00060 6e-189 yaaN P Belongs to the TelA family
LEHADEAE_00061 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LEHADEAE_00062 3.8e-30 csfB S Inhibitor of sigma-G Gin
LEHADEAE_00065 3.4e-39 S COG NOG14552 non supervised orthologous group
LEHADEAE_00066 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
LEHADEAE_00067 3.6e-32 yaaL S Protein of unknown function (DUF2508)
LEHADEAE_00068 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LEHADEAE_00069 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LEHADEAE_00070 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEHADEAE_00071 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LEHADEAE_00072 1.1e-98 yaaI Q COG1335 Amidases related to nicotinamidase
LEHADEAE_00073 1.7e-211 yaaH M Glycoside Hydrolase Family
LEHADEAE_00074 1e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
LEHADEAE_00075 4.5e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
LEHADEAE_00076 7.3e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LEHADEAE_00077 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LEHADEAE_00078 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LEHADEAE_00079 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LEHADEAE_00080 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LEHADEAE_00081 4e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LEHADEAE_00082 6.3e-182 yaaC S YaaC-like Protein
LEHADEAE_00085 3.4e-39 S COG NOG14552 non supervised orthologous group
LEHADEAE_00086 2.4e-20 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEHADEAE_00087 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEHADEAE_00088 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LEHADEAE_00089 8.1e-38 yaaB S Domain of unknown function (DUF370)
LEHADEAE_00090 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LEHADEAE_00091 2.4e-33 yaaA S S4 domain
LEHADEAE_00092 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LEHADEAE_00093 1.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LEHADEAE_00094 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LEHADEAE_00095 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEHADEAE_00096 1.3e-108 jag S single-stranded nucleic acid binding R3H
LEHADEAE_00097 1.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LEHADEAE_00098 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LEHADEAE_00099 1.6e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LEHADEAE_00100 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LEHADEAE_00101 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
LEHADEAE_00102 7.9e-149 spo0J K Belongs to the ParB family
LEHADEAE_00103 6.2e-111 yyaC S Sporulation protein YyaC
LEHADEAE_00104 8.3e-49 4.2.1.103 K FR47-like protein
LEHADEAE_00105 4e-176 yyaD S Membrane
LEHADEAE_00106 2.3e-33 yyzM S protein conserved in bacteria
LEHADEAE_00107 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEHADEAE_00108 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LEHADEAE_00109 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
LEHADEAE_00110 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LEHADEAE_00111 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LEHADEAE_00112 2.2e-105 adaA 3.2.2.21 K Transcriptional regulator
LEHADEAE_00113 1.8e-96 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEHADEAE_00114 2.3e-139 xth 3.1.11.2 L exodeoxyribonuclease III
LEHADEAE_00115 1.8e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
LEHADEAE_00116 4.9e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEHADEAE_00117 2.6e-247 ydjK G Sugar (and other) transporter
LEHADEAE_00118 5.6e-161 yyaK S CAAX protease self-immunity
LEHADEAE_00119 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
LEHADEAE_00120 2.7e-40 qacC U Small Multidrug Resistance protein
LEHADEAE_00122 3.3e-78 K Transcriptional regulator
LEHADEAE_00123 1.1e-99 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEHADEAE_00124 2.6e-129 ydfC EG EamA-like transporter family
LEHADEAE_00125 6.5e-252 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEHADEAE_00126 4.3e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LEHADEAE_00127 2.5e-161 K Transcriptional regulator
LEHADEAE_00128 2.3e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
LEHADEAE_00129 2.9e-162 eaeH M Domain of Unknown Function (DUF1259)
LEHADEAE_00131 1.4e-41 yjcF S Acetyltransferase (GNAT) domain
LEHADEAE_00132 1.6e-76 yybA 2.3.1.57 K transcriptional
LEHADEAE_00133 1e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LEHADEAE_00134 4.1e-69 ydgJ K Winged helix DNA-binding domain
LEHADEAE_00135 5.6e-115 drgA C nitroreductase
LEHADEAE_00136 2.2e-55 ypaA S Protein of unknown function (DUF1304)
LEHADEAE_00137 4.6e-158 G Major Facilitator Superfamily
LEHADEAE_00138 1.2e-57 dinB S PFAM DinB family protein
LEHADEAE_00139 8.4e-114 K FCD domain
LEHADEAE_00140 2.2e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
LEHADEAE_00141 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
LEHADEAE_00142 1.8e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LEHADEAE_00143 5e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
LEHADEAE_00144 8.2e-66 ydeP3 K Transcriptional regulator
LEHADEAE_00145 2.1e-83 cotF M Spore coat protein
LEHADEAE_00147 1.2e-158 yybS S membrane
LEHADEAE_00148 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LEHADEAE_00149 4.9e-73 rplI J binds to the 23S rRNA
LEHADEAE_00150 6.4e-122 KLT COG0515 Serine threonine protein kinase
LEHADEAE_00151 1.1e-121 S GlcNAc-PI de-N-acetylase
LEHADEAE_00152 4.3e-242 M Glycosyltransferase Family 4
LEHADEAE_00153 2.5e-233 S Carbamoyl-phosphate synthase L chain, ATP binding domain
LEHADEAE_00154 6.9e-203 S Ecdysteroid kinase
LEHADEAE_00155 2.2e-235 M Glycosyltransferase Family 4
LEHADEAE_00156 4.6e-17 yycC K YycC-like protein
LEHADEAE_00158 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
LEHADEAE_00159 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LEHADEAE_00160 8.5e-72 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEHADEAE_00161 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LEHADEAE_00166 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEHADEAE_00167 0.0 vicK 2.7.13.3 T Histidine kinase
LEHADEAE_00168 1.6e-260 yycH S protein conserved in bacteria
LEHADEAE_00169 1.1e-150 yycI S protein conserved in bacteria
LEHADEAE_00170 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LEHADEAE_00171 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEHADEAE_00172 2.1e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEHADEAE_00173 1.6e-247 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
LEHADEAE_00174 2.7e-188 2.7.7.73, 2.7.7.80 H ThiF family
LEHADEAE_00175 1.4e-256
LEHADEAE_00176 4.5e-195 S Major Facilitator Superfamily
LEHADEAE_00177 1.3e-304 S ABC transporter
LEHADEAE_00178 2.2e-144 1.14.11.27 P peptidyl-arginine hydroxylation
LEHADEAE_00179 2e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LEHADEAE_00180 2.2e-42 sdpR K transcriptional
LEHADEAE_00181 4.2e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LEHADEAE_00182 5.1e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
LEHADEAE_00183 3.8e-257 rocE E amino acid
LEHADEAE_00184 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
LEHADEAE_00185 1.1e-198 S Histidine kinase
LEHADEAE_00187 1.4e-86 yycN 2.3.1.128 K Acetyltransferase
LEHADEAE_00188 1.5e-183 C oxidoreductases (related to aryl-alcohol dehydrogenases)
LEHADEAE_00189 1e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LEHADEAE_00190 4.6e-216 yycP
LEHADEAE_00192 7.9e-08 S YyzF-like protein
LEHADEAE_00193 2.2e-79 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LEHADEAE_00194 1.5e-197 L Protein of unknown function (DUF1524)
LEHADEAE_00196 7.2e-18
LEHADEAE_00197 5.3e-176 S Fusaric acid resistance protein-like
LEHADEAE_00198 5.7e-186 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LEHADEAE_00199 7.4e-88 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
LEHADEAE_00200 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LEHADEAE_00201 2.2e-151 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LEHADEAE_00202 5.4e-83 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LEHADEAE_00203 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
LEHADEAE_00204 7.9e-244 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
LEHADEAE_00205 2.3e-287 ahpF O Alkyl hydroperoxide reductase
LEHADEAE_00206 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
LEHADEAE_00207 1.6e-91 mrr V Mrr N-terminal domain
LEHADEAE_00208 1e-21 3.4.24.84 O metalloendopeptidase activity
LEHADEAE_00209 2.3e-249 L COG0210 Superfamily I DNA and RNA helicases
LEHADEAE_00210 1.1e-124 E Ring-cleavage extradiol dioxygenase
LEHADEAE_00211 3.8e-73 yxaI S membrane protein domain
LEHADEAE_00212 1.9e-201 EGP Major facilitator Superfamily
LEHADEAE_00213 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
LEHADEAE_00214 1.7e-64 S Family of unknown function (DUF5391)
LEHADEAE_00215 2.8e-142 S PQQ-like domain
LEHADEAE_00216 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LEHADEAE_00217 3.1e-212 yxbF K Bacterial regulatory proteins, tetR family
LEHADEAE_00218 1.8e-198 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
LEHADEAE_00219 1.2e-200 desK 2.7.13.3 T Histidine kinase
LEHADEAE_00220 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEHADEAE_00221 1.8e-150 IQ Enoyl-(Acyl carrier protein) reductase
LEHADEAE_00223 0.0 htpG O Molecular chaperone. Has ATPase activity
LEHADEAE_00224 4.3e-245 csbC EGP Major facilitator Superfamily
LEHADEAE_00225 4.6e-174 iolS C Aldo keto reductase
LEHADEAE_00226 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
LEHADEAE_00227 4.8e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEHADEAE_00228 1.6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LEHADEAE_00229 2.7e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LEHADEAE_00230 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LEHADEAE_00231 4.4e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LEHADEAE_00232 6.7e-232 iolF EGP Major facilitator Superfamily
LEHADEAE_00233 4.4e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LEHADEAE_00234 8e-165 iolH G Xylose isomerase-like TIM barrel
LEHADEAE_00235 1.9e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LEHADEAE_00236 1.8e-156 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LEHADEAE_00237 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEHADEAE_00238 3.5e-177 T PhoQ Sensor
LEHADEAE_00239 3.6e-140 yxdL V ABC transporter, ATP-binding protein
LEHADEAE_00240 0.0 yxdM V ABC transporter (permease)
LEHADEAE_00241 1.3e-57 yxeA S Protein of unknown function (DUF1093)
LEHADEAE_00242 4.1e-178 fhuD P Periplasmic binding protein
LEHADEAE_00243 1.3e-34
LEHADEAE_00244 8.4e-23 yxeD
LEHADEAE_00248 2.6e-149 yidA S hydrolases of the HAD superfamily
LEHADEAE_00249 9.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LEHADEAE_00250 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LEHADEAE_00251 6.8e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEHADEAE_00252 8.7e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
LEHADEAE_00253 4.4e-253 lysP E amino acid
LEHADEAE_00254 1.6e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LEHADEAE_00255 1.7e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
LEHADEAE_00256 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LEHADEAE_00257 3.6e-285 hutH 4.3.1.3 E Histidine ammonia-lyase
LEHADEAE_00258 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LEHADEAE_00259 1e-273 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LEHADEAE_00260 5.2e-71 L NgoFVII restriction endonuclease
LEHADEAE_00261 8.5e-101 S GTP binding
LEHADEAE_00262 1.9e-182 2.1.1.37 H C-5 cytosine-specific DNA methylase
LEHADEAE_00263 5.1e-45 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
LEHADEAE_00264 1.1e-13 S Domain of unknown function (DUF5082)
LEHADEAE_00265 7e-102 L Replication protein
LEHADEAE_00266 3.4e-24
LEHADEAE_00268 2.5e-64 K Transcriptional regulator
LEHADEAE_00271 1.8e-72 yxiE T Belongs to the universal stress protein A family
LEHADEAE_00272 3.6e-147 yxxF EG EamA-like transporter family
LEHADEAE_00273 1.2e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
LEHADEAE_00274 0.0 wapA M COG3209 Rhs family protein
LEHADEAE_00275 2.1e-117
LEHADEAE_00276 1.2e-84 S Protein of unknown function (DUF4240)
LEHADEAE_00278 2.1e-62 yxxG
LEHADEAE_00279 2.3e-69 yxiG
LEHADEAE_00283 2.8e-32
LEHADEAE_00284 1e-78
LEHADEAE_00286 1.1e-14 S YxiJ-like protein
LEHADEAE_00287 1.3e-20
LEHADEAE_00288 7e-49 yxiI S Protein of unknown function (DUF2716)
LEHADEAE_00289 1.2e-61 S SMI1-KNR4 cell-wall
LEHADEAE_00292 1.5e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LEHADEAE_00293 4.3e-220 yxiO S COG2270 Permeases of the major facilitator superfamily
LEHADEAE_00294 1.5e-55 licT K transcriptional antiterminator
LEHADEAE_00295 2e-140 exoK GH16 M licheninase activity
LEHADEAE_00296 1.4e-221 citH C Citrate transporter
LEHADEAE_00297 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
LEHADEAE_00298 1.5e-49 yxiS
LEHADEAE_00299 1.8e-71 T Domain of unknown function (DUF4163)
LEHADEAE_00300 3.9e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEHADEAE_00301 2.6e-155 rlmA 2.1.1.187 Q Methyltransferase domain
LEHADEAE_00302 1.2e-216 yxjG 2.1.1.14 E Methionine synthase
LEHADEAE_00303 5.3e-86 yxjI S LURP-one-related
LEHADEAE_00306 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LEHADEAE_00307 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LEHADEAE_00308 3.8e-87 yxkC S Domain of unknown function (DUF4352)
LEHADEAE_00309 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEHADEAE_00310 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
LEHADEAE_00311 2.6e-205 msmK P Belongs to the ABC transporter superfamily
LEHADEAE_00312 1.6e-154 yxkH G Polysaccharide deacetylase
LEHADEAE_00313 1e-214 cimH C COG3493 Na citrate symporter
LEHADEAE_00314 5.9e-266 cydA 1.10.3.14 C oxidase, subunit
LEHADEAE_00315 5.7e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
LEHADEAE_00316 0.0 cydD V ATP-binding
LEHADEAE_00317 1e-291 cydD V ATP-binding protein
LEHADEAE_00318 4.2e-155 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LEHADEAE_00319 7.9e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
LEHADEAE_00320 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LEHADEAE_00321 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LEHADEAE_00322 2.1e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
LEHADEAE_00323 2.4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
LEHADEAE_00324 1.1e-164 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
LEHADEAE_00325 4.8e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEHADEAE_00326 2.3e-227 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEHADEAE_00327 8.6e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
LEHADEAE_00328 1.3e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
LEHADEAE_00329 6.5e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LEHADEAE_00330 1.7e-57 arsR K transcriptional
LEHADEAE_00331 3.7e-165 cbrA3 P Periplasmic binding protein
LEHADEAE_00332 1e-179 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEHADEAE_00333 2.8e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEHADEAE_00334 3.5e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LEHADEAE_00335 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
LEHADEAE_00336 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
LEHADEAE_00337 7.4e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEHADEAE_00338 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
LEHADEAE_00339 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEHADEAE_00340 1.9e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LEHADEAE_00341 3.1e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LEHADEAE_00342 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_00343 4.8e-229 dltB M membrane protein involved in D-alanine export
LEHADEAE_00344 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_00345 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
LEHADEAE_00346 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
LEHADEAE_00347 2.5e-115 ywaC 2.7.6.5 S protein conserved in bacteria
LEHADEAE_00348 4.1e-161 gspA M General stress
LEHADEAE_00349 4.9e-262 epr 3.4.21.62 O Belongs to the peptidase S8 family
LEHADEAE_00350 5.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEHADEAE_00351 7.6e-67 ywbC 4.4.1.5 E glyoxalase
LEHADEAE_00352 1e-223 ywbD 2.1.1.191 J Methyltransferase
LEHADEAE_00353 4.8e-137 mta K transcriptional
LEHADEAE_00354 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
LEHADEAE_00355 1.3e-109 ywbG M effector of murein hydrolase
LEHADEAE_00356 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LEHADEAE_00357 8.2e-152 ywbI K Transcriptional regulator
LEHADEAE_00358 1.3e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LEHADEAE_00359 1.9e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LEHADEAE_00360 2.6e-184 ywbN P Dyp-type peroxidase family protein
LEHADEAE_00361 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LEHADEAE_00362 1.2e-131 S Streptomycin biosynthesis protein StrF
LEHADEAE_00363 1.2e-128 H Methionine biosynthesis protein MetW
LEHADEAE_00365 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
LEHADEAE_00366 5.1e-61 gtcA S GtrA-like protein
LEHADEAE_00367 3.9e-295 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LEHADEAE_00368 8.4e-27 ywzA S membrane
LEHADEAE_00369 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LEHADEAE_00370 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEHADEAE_00371 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LEHADEAE_00372 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LEHADEAE_00373 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
LEHADEAE_00374 1.7e-76 ysnE K acetyltransferase
LEHADEAE_00375 1.6e-208 rodA D Belongs to the SEDS family
LEHADEAE_00376 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
LEHADEAE_00377 8.1e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEHADEAE_00378 0.0 vpr O Belongs to the peptidase S8 family
LEHADEAE_00380 2.8e-151 sacT K transcriptional antiterminator
LEHADEAE_00381 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEHADEAE_00382 4.1e-283 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
LEHADEAE_00383 7.4e-20 ywdA
LEHADEAE_00384 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEHADEAE_00385 6.3e-57 pex K Transcriptional regulator PadR-like family
LEHADEAE_00386 1.7e-87 ywdD
LEHADEAE_00388 1.8e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
LEHADEAE_00389 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LEHADEAE_00390 4.7e-41 ywdI S Family of unknown function (DUF5327)
LEHADEAE_00391 5.4e-229 ywdJ F Xanthine uracil
LEHADEAE_00392 4.2e-46 ywdK S small membrane protein
LEHADEAE_00393 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LEHADEAE_00394 1.7e-142 spsA M Spore Coat
LEHADEAE_00395 1e-273 spsB M Capsule polysaccharide biosynthesis protein
LEHADEAE_00396 4e-220 spsC E Belongs to the DegT DnrJ EryC1 family
LEHADEAE_00397 1.2e-155 spsD 2.3.1.210 K Spore Coat
LEHADEAE_00398 1.4e-214 spsE 2.5.1.56 M acid synthase
LEHADEAE_00399 2.6e-132 spsF M Spore Coat
LEHADEAE_00400 9.3e-181 spsG M Spore Coat
LEHADEAE_00401 1.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LEHADEAE_00402 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LEHADEAE_00403 4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LEHADEAE_00404 3e-86 spsL 5.1.3.13 M Spore Coat
LEHADEAE_00405 1.9e-59
LEHADEAE_00406 1.9e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LEHADEAE_00407 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LEHADEAE_00408 0.0 rocB E arginine degradation protein
LEHADEAE_00409 1.2e-258 lysP E amino acid
LEHADEAE_00410 9.3e-204 tcaB EGP Major facilitator Superfamily
LEHADEAE_00411 2.3e-221 ywfA EGP Major facilitator Superfamily
LEHADEAE_00412 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LEHADEAE_00413 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LEHADEAE_00414 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEHADEAE_00415 8.3e-268 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LEHADEAE_00416 1e-207 bacE EGP Major facilitator Superfamily
LEHADEAE_00417 1.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
LEHADEAE_00418 5.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
LEHADEAE_00419 2.3e-98 ywfI C May function as heme-dependent peroxidase
LEHADEAE_00420 1.5e-28 ywfI C May function as heme-dependent peroxidase
LEHADEAE_00421 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
LEHADEAE_00422 5.3e-157 MA20_14895 S Conserved hypothetical protein 698
LEHADEAE_00423 6e-163 cysL K Transcriptional regulator
LEHADEAE_00424 1.8e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LEHADEAE_00426 7e-175
LEHADEAE_00429 7.2e-167 yhcI S ABC transporter (permease)
LEHADEAE_00430 1.4e-162 V ABC transporter, ATP-binding protein
LEHADEAE_00431 1.2e-92 S membrane
LEHADEAE_00432 9.7e-52 padR K PadR family transcriptional regulator
LEHADEAE_00433 6.6e-110 rsfA_1
LEHADEAE_00434 6.9e-36 ywzC S Belongs to the UPF0741 family
LEHADEAE_00435 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
LEHADEAE_00436 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
LEHADEAE_00437 1.9e-245 yhdG_1 E C-terminus of AA_permease
LEHADEAE_00438 4.9e-67 ywhA K Transcriptional regulator
LEHADEAE_00439 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
LEHADEAE_00440 1.2e-117 ywhC S Peptidase family M50
LEHADEAE_00441 1.9e-92 ywhD S YwhD family
LEHADEAE_00442 1.8e-80
LEHADEAE_00443 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEHADEAE_00444 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LEHADEAE_00445 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
LEHADEAE_00448 1.3e-74 CP Membrane
LEHADEAE_00450 3.6e-31
LEHADEAE_00451 9.7e-29 ydcG K sequence-specific DNA binding
LEHADEAE_00453 4.7e-72 S aspartate phosphatase
LEHADEAE_00454 2.9e-43 ywiB S protein conserved in bacteria
LEHADEAE_00455 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LEHADEAE_00456 2.4e-212 narK P COG2223 Nitrate nitrite transporter
LEHADEAE_00457 1.9e-127 fnr K helix_turn_helix, cAMP Regulatory protein
LEHADEAE_00458 2.8e-139 ywiC S YwiC-like protein
LEHADEAE_00459 1.3e-84 arfM T cyclic nucleotide binding
LEHADEAE_00460 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEHADEAE_00461 1.2e-293 narH 1.7.5.1 C Nitrate reductase, beta
LEHADEAE_00462 4.8e-94 narJ 1.7.5.1 C nitrate reductase
LEHADEAE_00463 5.5e-121 narI 1.7.5.1 C nitrate reductase, gamma
LEHADEAE_00464 2.2e-103 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LEHADEAE_00465 1.6e-296 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEHADEAE_00466 0.0 ywjA V ABC transporter
LEHADEAE_00467 4.2e-43 ywjC
LEHADEAE_00468 4.9e-179 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LEHADEAE_00469 3.3e-217 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LEHADEAE_00470 0.0 fadF C COG0247 Fe-S oxidoreductase
LEHADEAE_00471 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LEHADEAE_00472 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LEHADEAE_00473 2.4e-92 ywjG S Domain of unknown function (DUF2529)
LEHADEAE_00474 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
LEHADEAE_00475 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
LEHADEAE_00476 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LEHADEAE_00477 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEHADEAE_00478 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
LEHADEAE_00479 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LEHADEAE_00480 1.1e-32 rpmE J Binds the 23S rRNA
LEHADEAE_00481 1.7e-102 tdk 2.7.1.21 F thymidine kinase
LEHADEAE_00482 0.0 sfcA 1.1.1.38 C malic enzyme
LEHADEAE_00483 6.8e-157 ywkB S Membrane transport protein
LEHADEAE_00484 2.8e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LEHADEAE_00485 3.4e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEHADEAE_00486 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LEHADEAE_00487 4.8e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LEHADEAE_00489 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
LEHADEAE_00490 8.9e-119 spoIIR S stage II sporulation protein R
LEHADEAE_00491 1.3e-73 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
LEHADEAE_00492 3.3e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LEHADEAE_00493 1.3e-83 mntP P Probably functions as a manganese efflux pump
LEHADEAE_00494 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEHADEAE_00495 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
LEHADEAE_00496 1.7e-96 ywlG S Belongs to the UPF0340 family
LEHADEAE_00497 1.1e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LEHADEAE_00498 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LEHADEAE_00499 2.1e-61 atpI S ATP synthase
LEHADEAE_00500 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
LEHADEAE_00501 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEHADEAE_00502 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LEHADEAE_00503 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LEHADEAE_00504 2.4e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LEHADEAE_00505 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LEHADEAE_00506 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LEHADEAE_00507 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LEHADEAE_00508 8.7e-89 ywmA
LEHADEAE_00509 4.8e-32 ywzB S membrane
LEHADEAE_00510 2.2e-134 ywmB S TATA-box binding
LEHADEAE_00511 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LEHADEAE_00512 1.2e-178 spoIID D Stage II sporulation protein D
LEHADEAE_00513 5.1e-114 ywmC S protein containing a von Willebrand factor type A (vWA) domain
LEHADEAE_00514 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
LEHADEAE_00516 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LEHADEAE_00517 4.1e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LEHADEAE_00518 2.8e-93 S response regulator aspartate phosphatase
LEHADEAE_00519 2.3e-81 ywmF S Peptidase M50
LEHADEAE_00520 1.4e-10 csbD K CsbD-like
LEHADEAE_00521 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LEHADEAE_00522 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LEHADEAE_00523 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LEHADEAE_00524 6.1e-67 ywnA K Transcriptional regulator
LEHADEAE_00525 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
LEHADEAE_00526 1.2e-51 ywnC S Family of unknown function (DUF5362)
LEHADEAE_00527 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LEHADEAE_00528 4.2e-69 ywnF S Family of unknown function (DUF5392)
LEHADEAE_00529 2e-10 ywnC S Family of unknown function (DUF5362)
LEHADEAE_00530 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
LEHADEAE_00531 1.4e-121 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
LEHADEAE_00532 5.6e-71 ywnJ S VanZ like family
LEHADEAE_00533 4.6e-100 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
LEHADEAE_00534 3.9e-207 ftsW D Belongs to the SEDS family
LEHADEAE_00535 2e-58 nrgB K Belongs to the P(II) protein family
LEHADEAE_00536 2.5e-228 amt P Ammonium transporter
LEHADEAE_00537 4.8e-102 phzA Q Isochorismatase family
LEHADEAE_00538 4.7e-244 ywoD EGP Major facilitator superfamily
LEHADEAE_00539 4.6e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
LEHADEAE_00540 1.9e-212 ywoG EGP Major facilitator Superfamily
LEHADEAE_00541 2.5e-71 ywoH K transcriptional
LEHADEAE_00542 1.8e-44 spoIIID K Stage III sporulation protein D
LEHADEAE_00543 2.7e-180 mbl D Rod shape-determining protein
LEHADEAE_00544 5.5e-128 flhO N flagellar basal body
LEHADEAE_00545 6.3e-143 flhP N flagellar basal body
LEHADEAE_00546 1.5e-197 S aspartate phosphatase
LEHADEAE_00547 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LEHADEAE_00548 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LEHADEAE_00549 2.5e-68 ywpF S YwpF-like protein
LEHADEAE_00550 4e-62 ywpG
LEHADEAE_00551 3.7e-57 ssbB L Single-stranded DNA-binding protein
LEHADEAE_00552 7.5e-138 glcR K DeoR C terminal sensor domain
LEHADEAE_00553 1.7e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
LEHADEAE_00554 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEHADEAE_00555 6e-307 ywqB S SWIM zinc finger
LEHADEAE_00556 1.3e-14
LEHADEAE_00557 8.3e-110 ywqC M biosynthesis protein
LEHADEAE_00558 9.6e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
LEHADEAE_00559 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
LEHADEAE_00560 8.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEHADEAE_00561 2.6e-146 ywqG S Domain of unknown function (DUF1963)
LEHADEAE_00563 1.4e-21 S Domain of unknown function (DUF5082)
LEHADEAE_00564 1.2e-36 ywqI S Family of unknown function (DUF5344)
LEHADEAE_00565 6.3e-302 ywqJ S Pre-toxin TG
LEHADEAE_00566 2.6e-49
LEHADEAE_00567 3.1e-41 S Protein of unknown function (DUF2004)
LEHADEAE_00569 4.5e-155 K Transcriptional regulator
LEHADEAE_00570 8.8e-93 ywqN S NAD(P)H-dependent
LEHADEAE_00572 3.2e-87 ywrA P COG2059 Chromate transport protein ChrA
LEHADEAE_00573 9.5e-101 ywrB P Chromate transporter
LEHADEAE_00574 2.5e-83 ywrC K Transcriptional regulator
LEHADEAE_00575 9.1e-300 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LEHADEAE_00577 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LEHADEAE_00578 2.2e-09
LEHADEAE_00579 5.5e-211 cotH M Spore Coat
LEHADEAE_00580 2.8e-128 cotB
LEHADEAE_00581 7.5e-126 ywrJ
LEHADEAE_00582 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LEHADEAE_00584 2.6e-166 alsR K LysR substrate binding domain
LEHADEAE_00585 2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LEHADEAE_00586 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
LEHADEAE_00587 5.3e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
LEHADEAE_00588 9.8e-89 batE T Sh3 type 3 domain protein
LEHADEAE_00589 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
LEHADEAE_00590 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
LEHADEAE_00591 7.1e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LEHADEAE_00592 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LEHADEAE_00593 2.4e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LEHADEAE_00594 3.2e-178 rbsR K transcriptional
LEHADEAE_00595 1.5e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
LEHADEAE_00596 8.2e-191 gerKB E Spore germination protein
LEHADEAE_00597 2.8e-186 gerKA EG Spore germination protein
LEHADEAE_00598 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
LEHADEAE_00599 2.3e-70 pgsC S biosynthesis protein
LEHADEAE_00600 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LEHADEAE_00601 1.3e-20 ywtC
LEHADEAE_00602 9.5e-236 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LEHADEAE_00603 3.8e-35 yttA 2.7.13.3 S Pfam Transposase IS66
LEHADEAE_00604 1.8e-156 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
LEHADEAE_00605 7.2e-178 ywtF K Transcriptional regulator
LEHADEAE_00606 4.9e-249 ywtG EGP Major facilitator Superfamily
LEHADEAE_00607 1.5e-266 GT2,GT4 J Glycosyl transferase family 2
LEHADEAE_00608 6.3e-210 gerAC S Spore germination protein
LEHADEAE_00609 7.8e-197 gerBB E Spore germination protein
LEHADEAE_00610 3.7e-263 gerBA EG Spore germination protein
LEHADEAE_00611 5.9e-185 pmi 5.3.1.8 G mannose-6-phosphate isomerase
LEHADEAE_00612 6.1e-240 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEHADEAE_00613 1.6e-216 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LEHADEAE_00614 1.4e-141 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LEHADEAE_00615 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
LEHADEAE_00616 7.8e-280 M Glycosyltransferase like family 2
LEHADEAE_00617 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LEHADEAE_00618 1.7e-151 tagG GM Transport permease protein
LEHADEAE_00619 2.4e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LEHADEAE_00620 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEHADEAE_00621 1.3e-207 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LEHADEAE_00622 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LEHADEAE_00623 2.3e-48
LEHADEAE_00624 0.0 lytB 3.5.1.28 D Stage II sporulation protein
LEHADEAE_00625 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEHADEAE_00626 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LEHADEAE_00627 6.1e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEHADEAE_00628 6.8e-223 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
LEHADEAE_00629 3.8e-246 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEHADEAE_00630 2.6e-253 tuaE M Teichuronic acid biosynthesis protein
LEHADEAE_00631 6.6e-114 tuaF M protein involved in exopolysaccharide biosynthesis
LEHADEAE_00632 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
LEHADEAE_00633 3.9e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
LEHADEAE_00634 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LEHADEAE_00635 1e-165 yvhJ K Transcriptional regulator
LEHADEAE_00636 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
LEHADEAE_00637 3.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LEHADEAE_00638 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEHADEAE_00639 3.2e-158 degV S protein conserved in bacteria
LEHADEAE_00640 1.2e-255 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LEHADEAE_00641 1.7e-42 comFB S Late competence development protein ComFB
LEHADEAE_00642 2.9e-76 comFC S Phosphoribosyl transferase domain
LEHADEAE_00643 7.8e-73 yvyF S flagellar protein
LEHADEAE_00644 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
LEHADEAE_00645 8.9e-81 flgN NOU FlgN protein
LEHADEAE_00646 1.4e-273 flgK N flagellar hook-associated protein
LEHADEAE_00647 2.3e-162 flgL N Belongs to the bacterial flagellin family
LEHADEAE_00648 8.9e-80 yviE
LEHADEAE_00649 7.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LEHADEAE_00650 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LEHADEAE_00651 2e-103 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LEHADEAE_00652 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LEHADEAE_00653 3e-66 fliS N flagellar protein FliS
LEHADEAE_00654 4.5e-10 fliT S bacterial-type flagellum organization
LEHADEAE_00655 6.8e-68
LEHADEAE_00656 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LEHADEAE_00657 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LEHADEAE_00658 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LEHADEAE_00659 9.7e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
LEHADEAE_00660 2.3e-122 ftsE D cell division ATP-binding protein FtsE
LEHADEAE_00661 4.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LEHADEAE_00662 1e-225 ywoF P Right handed beta helix region
LEHADEAE_00663 1.1e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
LEHADEAE_00664 1.5e-55 swrA S Swarming motility protein
LEHADEAE_00665 1.4e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEHADEAE_00666 4.1e-24 yuaB
LEHADEAE_00667 1.6e-225 yvkA EGP Major facilitator Superfamily
LEHADEAE_00668 7e-110 yvkB K Transcriptional regulator
LEHADEAE_00669 0.0 yvkC 2.7.9.2 GT Phosphotransferase
LEHADEAE_00670 7.6e-33 csbA S protein conserved in bacteria
LEHADEAE_00671 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LEHADEAE_00672 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LEHADEAE_00673 2.2e-32 yvkN
LEHADEAE_00674 6.1e-49 yvlA
LEHADEAE_00675 1.2e-165 yvlB S Putative adhesin
LEHADEAE_00676 9.6e-26 pspB KT PspC domain
LEHADEAE_00677 1.5e-40 yvlD S Membrane
LEHADEAE_00678 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
LEHADEAE_00679 4.4e-103 yxaF K Transcriptional regulator
LEHADEAE_00680 2.3e-133 yvoA K transcriptional
LEHADEAE_00681 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LEHADEAE_00682 3e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LEHADEAE_00683 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LEHADEAE_00684 2.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LEHADEAE_00685 5.9e-112 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LEHADEAE_00686 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
LEHADEAE_00687 3.5e-137 yvpB NU protein conserved in bacteria
LEHADEAE_00688 1.1e-206 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LEHADEAE_00689 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LEHADEAE_00690 6.8e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LEHADEAE_00691 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LEHADEAE_00692 1.6e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LEHADEAE_00693 2.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LEHADEAE_00694 1.7e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LEHADEAE_00695 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
LEHADEAE_00696 0.0 msbA2 3.6.3.44 V ABC transporter
LEHADEAE_00697 1.9e-51
LEHADEAE_00698 1.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEHADEAE_00699 8.8e-190 sasA T Histidine kinase
LEHADEAE_00700 5e-276 S COG0457 FOG TPR repeat
LEHADEAE_00701 1.3e-124 usp CBM50 M protein conserved in bacteria
LEHADEAE_00702 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LEHADEAE_00703 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LEHADEAE_00704 1.1e-166 rapZ S Displays ATPase and GTPase activities
LEHADEAE_00705 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LEHADEAE_00706 5.3e-170 whiA K May be required for sporulation
LEHADEAE_00707 4.7e-36 crh G Phosphocarrier protein Chr
LEHADEAE_00708 2.8e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
LEHADEAE_00709 8.2e-79 M Ribonuclease
LEHADEAE_00710 2.1e-182 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEHADEAE_00711 1.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LEHADEAE_00712 1.6e-280 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
LEHADEAE_00713 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
LEHADEAE_00714 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
LEHADEAE_00715 5.3e-11 yvdD 3.2.2.10 S Belongs to the LOG family
LEHADEAE_00716 4.6e-247 EGP Sugar (and other) transporter
LEHADEAE_00717 1.4e-209 yraM S PrpF protein
LEHADEAE_00718 6.7e-164 yraN K Transcriptional regulator
LEHADEAE_00719 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LEHADEAE_00720 1.6e-182 scrR K transcriptional
LEHADEAE_00721 2.3e-218 rafB P LacY proton/sugar symporter
LEHADEAE_00722 5.5e-291 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
LEHADEAE_00724 1.7e-32
LEHADEAE_00725 1.1e-240 I Pfam Lipase (class 3)
LEHADEAE_00726 2.3e-15 S Protein of unknown function (DUF1433)
LEHADEAE_00727 2.2e-38 S Protein of unknown function (DUF1433)
LEHADEAE_00728 1.6e-93 padC Q Phenolic acid decarboxylase
LEHADEAE_00729 2.3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEHADEAE_00730 3.4e-112 yyaS S Membrane
LEHADEAE_00731 3.7e-96 ywjB H RibD C-terminal domain
LEHADEAE_00733 1.9e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
LEHADEAE_00734 1.9e-77 slr K transcriptional
LEHADEAE_00735 1.6e-118 ywqC M biosynthesis protein
LEHADEAE_00736 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
LEHADEAE_00737 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
LEHADEAE_00738 3.3e-219 epsD GT4 M Glycosyl transferase 4-like
LEHADEAE_00739 7.6e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEHADEAE_00740 4.4e-211 epsF GT4 M Glycosyl transferases group 1
LEHADEAE_00741 7.7e-205 epsG S EpsG family
LEHADEAE_00742 1.9e-192 epsH GT2 S Glycosyltransferase like family 2
LEHADEAE_00743 1.9e-203 epsI GM pyruvyl transferase
LEHADEAE_00744 1.4e-192 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
LEHADEAE_00745 5.3e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEHADEAE_00746 3.7e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LEHADEAE_00747 4.2e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
LEHADEAE_00748 2.6e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LEHADEAE_00749 1.6e-185 yvfF GM Exopolysaccharide biosynthesis protein
LEHADEAE_00750 2.7e-32 yvfG S YvfG protein
LEHADEAE_00751 7.2e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LEHADEAE_00752 3.8e-304 yvfH C L-lactate permease
LEHADEAE_00753 1.5e-119 yvfI K COG2186 Transcriptional regulators
LEHADEAE_00754 3.9e-218 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEHADEAE_00755 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LEHADEAE_00756 4e-270 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LEHADEAE_00757 7.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LEHADEAE_00758 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
LEHADEAE_00759 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
LEHADEAE_00760 1.5e-150 ybbH_1 K RpiR family transcriptional regulator
LEHADEAE_00762 1.1e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
LEHADEAE_00763 7.7e-158 yvbV EG EamA-like transporter family
LEHADEAE_00764 2.4e-156 yvbU K Transcriptional regulator
LEHADEAE_00766 4.2e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEHADEAE_00767 2.5e-203 araR K transcriptional
LEHADEAE_00768 7.4e-253 araE EGP Major facilitator Superfamily
LEHADEAE_00770 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LEHADEAE_00771 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEHADEAE_00772 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LEHADEAE_00773 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LEHADEAE_00774 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
LEHADEAE_00775 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LEHADEAE_00776 5.8e-236 ywaD 3.4.11.10, 3.4.11.6 S PA domain
LEHADEAE_00777 8.9e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LEHADEAE_00778 1.7e-215 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LEHADEAE_00779 1.8e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
LEHADEAE_00780 7.7e-225 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LEHADEAE_00781 1e-146 M Protein involved in cellulose biosynthesis
LEHADEAE_00782 2.1e-142 C WbqC-like protein family
LEHADEAE_00783 7e-124 S GlcNAc-PI de-N-acetylase
LEHADEAE_00784 3.3e-177
LEHADEAE_00785 8.1e-211 EGP Major facilitator Superfamily
LEHADEAE_00786 1.5e-80 yvbK 3.1.3.25 K acetyltransferase
LEHADEAE_00787 0.0 tcaA S response to antibiotic
LEHADEAE_00788 1.1e-119 exoY M Membrane
LEHADEAE_00789 9.8e-104 yvbG U UPF0056 membrane protein
LEHADEAE_00790 3.5e-97 yvbF K Belongs to the GbsR family
LEHADEAE_00791 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LEHADEAE_00792 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LEHADEAE_00793 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEHADEAE_00794 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LEHADEAE_00795 4.3e-76 yvbF K Belongs to the GbsR family
LEHADEAE_00796 8.6e-207 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LEHADEAE_00797 6.6e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LEHADEAE_00798 3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LEHADEAE_00799 1.8e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LEHADEAE_00800 1.2e-126 mutF V ABC transporter, ATP-binding protein
LEHADEAE_00801 6e-121 spaE S ABC-2 family transporter protein
LEHADEAE_00802 4.7e-132 mutG S ABC-2 family transporter protein
LEHADEAE_00803 1.4e-121 K Transcriptional regulatory protein, C terminal
LEHADEAE_00804 5.3e-259 T His Kinase A (phosphoacceptor) domain
LEHADEAE_00805 8.8e-53 yodB K transcriptional
LEHADEAE_00806 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
LEHADEAE_00807 1e-69 K transcriptional
LEHADEAE_00808 6e-35 yvzC K Transcriptional
LEHADEAE_00809 4.8e-24 secG U Preprotein translocase subunit SecG
LEHADEAE_00810 1.6e-142 est 3.1.1.1 S Carboxylesterase
LEHADEAE_00811 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LEHADEAE_00812 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LEHADEAE_00814 4.4e-49 yrdF K ribonuclease inhibitor
LEHADEAE_00815 6.9e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEHADEAE_00816 2.5e-161 ytlI K LysR substrate binding domain
LEHADEAE_00817 3e-101 ytmI K Acetyltransferase (GNAT) domain
LEHADEAE_00818 2.5e-128 ytmJ ET Bacterial periplasmic substrate-binding proteins
LEHADEAE_00819 2.3e-145 tcyK M Bacterial periplasmic substrate-binding proteins
LEHADEAE_00820 6.6e-120 tcyL P Binding-protein-dependent transport system inner membrane component
LEHADEAE_00821 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
LEHADEAE_00822 3.6e-140 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEHADEAE_00823 2.4e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEHADEAE_00824 5.6e-46 ytnI O COG0695 Glutaredoxin and related proteins
LEHADEAE_00825 2.4e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEHADEAE_00827 2.5e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEHADEAE_00828 4.6e-191 yvaA 1.1.1.371 S Oxidoreductase
LEHADEAE_00829 3.7e-48 csoR S transcriptional
LEHADEAE_00830 2.6e-29 copZ P Heavy-metal-associated domain
LEHADEAE_00831 0.0 copA 3.6.3.54 P P-type ATPase
LEHADEAE_00832 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LEHADEAE_00833 7.7e-99 bdbD O Thioredoxin
LEHADEAE_00834 6e-73 bdbC O Required for disulfide bond formation in some proteins
LEHADEAE_00835 4.4e-141 S Metallo-peptidase family M12
LEHADEAE_00836 2.9e-97 yvgT S membrane
LEHADEAE_00837 0.0 helD 3.6.4.12 L DNA helicase
LEHADEAE_00838 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LEHADEAE_00839 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LEHADEAE_00840 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
LEHADEAE_00841 2.7e-85 yvgO
LEHADEAE_00842 1.1e-155 yvgN S reductase
LEHADEAE_00843 7e-193 yfiN V COG0842 ABC-type multidrug transport system, permease component
LEHADEAE_00844 1.3e-191 yfiM V ABC-2 type transporter
LEHADEAE_00845 5.4e-167 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
LEHADEAE_00846 4.3e-179 T Histidine kinase
LEHADEAE_00847 8.6e-114 yfiK K Regulator
LEHADEAE_00848 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
LEHADEAE_00849 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
LEHADEAE_00850 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
LEHADEAE_00851 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LEHADEAE_00852 5.1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
LEHADEAE_00853 5.2e-13 S Small spore protein J (Spore_SspJ)
LEHADEAE_00854 7e-235 yvsH E Arginine ornithine antiporter
LEHADEAE_00855 3.7e-128 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LEHADEAE_00856 8.9e-178 fhuD P ABC transporter
LEHADEAE_00857 2.5e-173 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEHADEAE_00858 1.6e-146 fhuC 3.6.3.34 HP ABC transporter
LEHADEAE_00859 9.3e-66 yvrL S Regulatory protein YrvL
LEHADEAE_00860 7.8e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
LEHADEAE_00861 6.1e-15 S YvrJ protein family
LEHADEAE_00862 3.8e-102 yvrI K RNA polymerase
LEHADEAE_00863 1.1e-36
LEHADEAE_00864 2.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEHADEAE_00865 0.0 T PhoQ Sensor
LEHADEAE_00866 4.2e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
LEHADEAE_00867 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEHADEAE_00868 4.6e-166 yvrC P ABC transporter substrate-binding protein
LEHADEAE_00869 5.8e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEHADEAE_00870 8e-219 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LEHADEAE_00871 7e-101 yvqK 2.5.1.17 S Adenosyltransferase
LEHADEAE_00872 2.2e-227 yvqJ EGP Major facilitator Superfamily
LEHADEAE_00873 9e-44 liaI S membrane
LEHADEAE_00874 3.3e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LEHADEAE_00875 3.3e-126 liaG S Putative adhesin
LEHADEAE_00876 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
LEHADEAE_00877 2.3e-193 vraS 2.7.13.3 T Histidine kinase
LEHADEAE_00878 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEHADEAE_00879 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
LEHADEAE_00880 3.6e-186 gerAB E Spore germination protein
LEHADEAE_00881 1.2e-258 gerAA EG Spore germination protein
LEHADEAE_00882 6.6e-24 S Protein of unknown function (DUF3970)
LEHADEAE_00883 8.7e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LEHADEAE_00884 2.9e-157 yuxN K Transcriptional regulator
LEHADEAE_00885 3.4e-24
LEHADEAE_00886 2.5e-250 cssS 2.7.13.3 T PhoQ Sensor
LEHADEAE_00887 2.8e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEHADEAE_00888 3.8e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEHADEAE_00889 1.4e-78 dps P Belongs to the Dps family
LEHADEAE_00890 3.9e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEHADEAE_00891 0.0 pepF2 E COG1164 Oligoendopeptidase F
LEHADEAE_00892 7.2e-45 S YusW-like protein
LEHADEAE_00893 3.1e-150 yusV 3.6.3.34 HP ABC transporter
LEHADEAE_00894 3.3e-39 yusU S Protein of unknown function (DUF2573)
LEHADEAE_00895 2.2e-185 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEHADEAE_00896 4.2e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
LEHADEAE_00897 1e-154 ywbI2 K Transcriptional regulator
LEHADEAE_00898 4e-287 yusP P Major facilitator superfamily
LEHADEAE_00899 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
LEHADEAE_00900 1.1e-53 yusN M Coat F domain
LEHADEAE_00901 5.7e-42
LEHADEAE_00902 8.4e-165 fadM E Proline dehydrogenase
LEHADEAE_00903 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
LEHADEAE_00904 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
LEHADEAE_00905 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
LEHADEAE_00906 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
LEHADEAE_00907 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LEHADEAE_00908 3.7e-40 yusG S Protein of unknown function (DUF2553)
LEHADEAE_00909 4.9e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
LEHADEAE_00910 1.6e-54 yusE CO Thioredoxin
LEHADEAE_00911 1.5e-56 yusD S SCP-2 sterol transfer family
LEHADEAE_00912 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LEHADEAE_00913 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
LEHADEAE_00914 3e-145 metQ P Belongs to the NlpA lipoprotein family
LEHADEAE_00915 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LEHADEAE_00916 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LEHADEAE_00917 1.2e-244 sufD O assembly protein SufD
LEHADEAE_00918 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LEHADEAE_00919 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
LEHADEAE_00920 8.7e-270 sufB O FeS cluster assembly
LEHADEAE_00921 2.3e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LEHADEAE_00922 2.5e-25 yncE S Protein of unknown function (DUF2691)
LEHADEAE_00923 1.8e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
LEHADEAE_00924 7e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
LEHADEAE_00926 5e-165 K helix_turn_helix, mercury resistance
LEHADEAE_00927 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LEHADEAE_00928 1.7e-243 yurO G COG1653 ABC-type sugar transport system, periplasmic component
LEHADEAE_00929 1.5e-158 yurN G Binding-protein-dependent transport system inner membrane component
LEHADEAE_00930 6.9e-164 yurM P COG0395 ABC-type sugar transport system, permease component
LEHADEAE_00931 9e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
LEHADEAE_00932 6.8e-133 yurK K UTRA
LEHADEAE_00933 2.7e-205 msmX P Belongs to the ABC transporter superfamily
LEHADEAE_00934 5.6e-166 bsn L Ribonuclease
LEHADEAE_00935 1.8e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LEHADEAE_00936 1.8e-234 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LEHADEAE_00937 9.2e-212 blt EGP Major facilitator Superfamily
LEHADEAE_00940 6.4e-301 pucR QT COG2508 Regulator of polyketide synthase expression
LEHADEAE_00941 2.9e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LEHADEAE_00942 3.5e-58 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
LEHADEAE_00943 1.5e-168 yunF S Protein of unknown function DUF72
LEHADEAE_00944 1.1e-144 yunE S membrane transporter protein
LEHADEAE_00945 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LEHADEAE_00946 3.3e-130 yunB S Sporulation protein YunB (Spo_YunB)
LEHADEAE_00947 1.9e-191 lytH M Peptidase, M23
LEHADEAE_00948 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LEHADEAE_00949 1.7e-47 yutD S protein conserved in bacteria
LEHADEAE_00950 6.8e-72 yutE S Protein of unknown function DUF86
LEHADEAE_00951 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LEHADEAE_00952 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LEHADEAE_00953 3e-195 yutH S Spore coat protein
LEHADEAE_00954 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
LEHADEAE_00955 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LEHADEAE_00956 9.8e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LEHADEAE_00957 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
LEHADEAE_00958 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
LEHADEAE_00959 2.8e-54 yuzD S protein conserved in bacteria
LEHADEAE_00960 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
LEHADEAE_00961 2.4e-39 yuzB S Belongs to the UPF0349 family
LEHADEAE_00962 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LEHADEAE_00963 1.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LEHADEAE_00964 1.1e-62 erpA S Belongs to the HesB IscA family
LEHADEAE_00965 1.2e-135 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
LEHADEAE_00966 2.3e-26 K helix_turn_helix, mercury resistance
LEHADEAE_00968 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
LEHADEAE_00970 1.5e-121 V ABC transporter
LEHADEAE_00971 1e-69 CP Membrane
LEHADEAE_00972 4.8e-29
LEHADEAE_00973 7.4e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LEHADEAE_00975 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
LEHADEAE_00976 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
LEHADEAE_00977 9.9e-28 yuiB S Putative membrane protein
LEHADEAE_00978 2.7e-117 yuiC S protein conserved in bacteria
LEHADEAE_00979 1.6e-77 yuiD S protein conserved in bacteria
LEHADEAE_00980 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LEHADEAE_00981 1.2e-207 yuiF S antiporter
LEHADEAE_00982 1.1e-101 bioY S Biotin biosynthesis protein
LEHADEAE_00983 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
LEHADEAE_00984 1.4e-164 besA S Putative esterase
LEHADEAE_00985 1.8e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEHADEAE_00986 1.7e-218 entC 5.4.4.2 HQ Isochorismate synthase
LEHADEAE_00987 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
LEHADEAE_00988 3.6e-171 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
LEHADEAE_00989 8.4e-216 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_00990 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_00991 1.1e-33 mbtH S MbtH-like protein
LEHADEAE_00992 1.2e-131 yukJ S Uncharacterized conserved protein (DUF2278)
LEHADEAE_00993 2.3e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
LEHADEAE_00994 4.2e-228 yukF QT Transcriptional regulator
LEHADEAE_00995 3.3e-46 esxA S Belongs to the WXG100 family
LEHADEAE_00996 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
LEHADEAE_00997 1.2e-204 essB S WXG100 protein secretion system (Wss), protein YukC
LEHADEAE_00998 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LEHADEAE_00999 0.0 esaA S type VII secretion protein EsaA
LEHADEAE_01000 1.3e-76 yueC S Family of unknown function (DUF5383)
LEHADEAE_01001 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEHADEAE_01002 8.3e-96 yueE S phosphohydrolase
LEHADEAE_01003 1.6e-22 S Protein of unknown function (DUF2642)
LEHADEAE_01004 1e-185 yueF S transporter activity
LEHADEAE_01005 6.4e-34 yueG S Spore germination protein gerPA/gerPF
LEHADEAE_01006 2.8e-38 yueH S YueH-like protein
LEHADEAE_01007 7.2e-68 yueI S Protein of unknown function (DUF1694)
LEHADEAE_01008 4.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
LEHADEAE_01009 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LEHADEAE_01010 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
LEHADEAE_01011 1.2e-50 yuzC
LEHADEAE_01014 4.4e-62 comQ H Polyprenyl synthetase
LEHADEAE_01016 5.3e-256 comP 2.7.13.3 T Histidine kinase
LEHADEAE_01017 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEHADEAE_01018 4.3e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
LEHADEAE_01019 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
LEHADEAE_01020 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEHADEAE_01021 8.5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEHADEAE_01022 1.7e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEHADEAE_01023 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEHADEAE_01024 1.3e-67 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LEHADEAE_01025 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LEHADEAE_01026 2.3e-12
LEHADEAE_01027 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
LEHADEAE_01028 8.4e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
LEHADEAE_01029 6.1e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LEHADEAE_01030 1.7e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
LEHADEAE_01031 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
LEHADEAE_01032 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LEHADEAE_01033 9.3e-74 yufK S Family of unknown function (DUF5366)
LEHADEAE_01034 2.2e-72 yuxK S protein conserved in bacteria
LEHADEAE_01035 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
LEHADEAE_01036 1.8e-178 yuxJ EGP Major facilitator Superfamily
LEHADEAE_01037 4e-118 kapD L the KinA pathway to sporulation
LEHADEAE_01038 7.7e-67 kapB G Kinase associated protein B
LEHADEAE_01039 8.9e-229 T PhoQ Sensor
LEHADEAE_01040 3.3e-222 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LEHADEAE_01041 1.9e-40 yugE S Domain of unknown function (DUF1871)
LEHADEAE_01042 5.5e-155 yugF I Hydrolase
LEHADEAE_01043 2e-83 alaR K Transcriptional regulator
LEHADEAE_01044 1.6e-208 yugH 2.6.1.1 E Aminotransferase
LEHADEAE_01045 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
LEHADEAE_01046 1.8e-34 yuzA S Domain of unknown function (DUF378)
LEHADEAE_01047 1.4e-225 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
LEHADEAE_01048 1.8e-228 yugK C Dehydrogenase
LEHADEAE_01049 5.5e-118 ycaC Q Isochorismatase family
LEHADEAE_01050 2.5e-17 S NADPH-dependent FMN reductase
LEHADEAE_01051 1.6e-45 S NADPH-dependent FMN reductase
LEHADEAE_01052 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
LEHADEAE_01054 7e-71 yugN S YugN-like family
LEHADEAE_01055 1.2e-180 yugO P COG1226 Kef-type K transport systems
LEHADEAE_01056 6.7e-27 mstX S Membrane-integrating protein Mistic
LEHADEAE_01057 3.4e-18
LEHADEAE_01058 8.3e-117 yugP S Zn-dependent protease
LEHADEAE_01059 2.5e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
LEHADEAE_01060 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
LEHADEAE_01061 5.9e-73 yugU S Uncharacterised protein family UPF0047
LEHADEAE_01062 2.3e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LEHADEAE_01063 1.4e-40
LEHADEAE_01064 2.2e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
LEHADEAE_01065 8.1e-221 mcpA NT chemotaxis protein
LEHADEAE_01066 1.2e-235 mcpA NT chemotaxis protein
LEHADEAE_01067 6e-224 mcpA NT chemotaxis protein
LEHADEAE_01068 2.6e-235 mcpA NT chemotaxis protein
LEHADEAE_01069 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
LEHADEAE_01070 4.7e-185 ygjR S Oxidoreductase
LEHADEAE_01071 3.8e-194 yubA S transporter activity
LEHADEAE_01072 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LEHADEAE_01074 3.8e-17
LEHADEAE_01076 6.8e-14
LEHADEAE_01078 7.6e-131 S Aspartate phosphatase response regulator
LEHADEAE_01082 1e-48 yjcN
LEHADEAE_01083 1.4e-118 G Cupin
LEHADEAE_01084 4.2e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LEHADEAE_01085 9e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LEHADEAE_01086 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
LEHADEAE_01087 7.9e-94 yuaB
LEHADEAE_01088 8.6e-96 yuaC K Belongs to the GbsR family
LEHADEAE_01089 1.5e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
LEHADEAE_01090 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
LEHADEAE_01091 2.5e-109 yuaD S MOSC domain
LEHADEAE_01092 6.9e-73 yuaE S DinB superfamily
LEHADEAE_01093 7.3e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
LEHADEAE_01094 5e-178 yuaG 3.4.21.72 S protein conserved in bacteria
LEHADEAE_01095 8.2e-97 thiT S Thiamine transporter protein (Thia_YuaJ)
LEHADEAE_01099 1.1e-164 ygxA S Nucleotidyltransferase-like
LEHADEAE_01100 1.5e-56 ygzB S UPF0295 protein
LEHADEAE_01101 1.8e-80 perR P Belongs to the Fur family
LEHADEAE_01102 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
LEHADEAE_01103 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LEHADEAE_01104 2.7e-178 ygaE S Membrane
LEHADEAE_01105 3.5e-300 ygaD V ABC transporter
LEHADEAE_01106 2.2e-104 ygaC J Belongs to the UPF0374 family
LEHADEAE_01107 1.5e-37 ygaB S YgaB-like protein
LEHADEAE_01109 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEHADEAE_01110 3.1e-36 yfhS
LEHADEAE_01111 4.8e-207 mutY L A G-specific
LEHADEAE_01112 8.8e-185 yfhP S membrane-bound metal-dependent
LEHADEAE_01113 0.0 yfhO S Bacterial membrane protein YfhO
LEHADEAE_01114 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEHADEAE_01115 1.7e-170 yfhM S Alpha/beta hydrolase family
LEHADEAE_01116 9.7e-34 yfhL S SdpI/YhfL protein family
LEHADEAE_01117 1.7e-93 batE T Bacterial SH3 domain homologues
LEHADEAE_01118 2.2e-44 yfhJ S WVELL protein
LEHADEAE_01119 5.3e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
LEHADEAE_01120 1.1e-204 yfhI EGP Major facilitator Superfamily
LEHADEAE_01121 2.5e-52 yfhH S Protein of unknown function (DUF1811)
LEHADEAE_01122 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
LEHADEAE_01123 3.4e-166 yfhF S nucleoside-diphosphate sugar epimerase
LEHADEAE_01125 6.1e-25 yfhD S YfhD-like protein
LEHADEAE_01126 3.3e-106 yfhC C nitroreductase
LEHADEAE_01127 8.5e-162 yfhB 5.3.3.17 S PhzF family
LEHADEAE_01128 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LEHADEAE_01129 6.2e-82 yfiV K transcriptional
LEHADEAE_01130 1.1e-289 yfiU EGP Major facilitator Superfamily
LEHADEAE_01131 2.6e-97 yfiT S Belongs to the metal hydrolase YfiT family
LEHADEAE_01132 4.5e-45 yrdF K ribonuclease inhibitor
LEHADEAE_01133 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
LEHADEAE_01134 1.9e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LEHADEAE_01135 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
LEHADEAE_01136 6.6e-96 padR K transcriptional
LEHADEAE_01137 1.4e-165 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LEHADEAE_01138 7.2e-158 yfiE 1.13.11.2 S glyoxalase
LEHADEAE_01139 9.2e-63 mhqP S DoxX
LEHADEAE_01140 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEHADEAE_01141 4.5e-308 yfiB3 V ABC transporter
LEHADEAE_01142 3.2e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEHADEAE_01143 5.1e-139 glvR F Helix-turn-helix domain, rpiR family
LEHADEAE_01144 2.2e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LEHADEAE_01145 4.2e-15 sspH S Belongs to the SspH family
LEHADEAE_01146 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
LEHADEAE_01147 1.2e-250 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEHADEAE_01148 1.1e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEHADEAE_01149 8.8e-187 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEHADEAE_01150 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEHADEAE_01151 2.8e-87 yfjM S Psort location Cytoplasmic, score
LEHADEAE_01152 3.5e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LEHADEAE_01153 8.7e-44 S YfzA-like protein
LEHADEAE_01154 2.1e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEHADEAE_01155 7.5e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LEHADEAE_01156 8.5e-184 corA P Mediates influx of magnesium ions
LEHADEAE_01157 1.8e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LEHADEAE_01158 9e-155 pdaA G deacetylase
LEHADEAE_01159 4.9e-27 yfjT
LEHADEAE_01160 3.3e-219 yfkA S YfkB-like domain
LEHADEAE_01161 2.6e-144 yfkC M Mechanosensitive ion channel
LEHADEAE_01162 1.6e-143 yfkD S YfkD-like protein
LEHADEAE_01163 2.2e-185 cax P COG0387 Ca2 H antiporter
LEHADEAE_01164 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
LEHADEAE_01165 2.5e-07
LEHADEAE_01166 7.6e-144 yihY S Belongs to the UPF0761 family
LEHADEAE_01167 1.7e-51 yfkI S gas vesicle protein
LEHADEAE_01168 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LEHADEAE_01169 2.7e-29 yfkK S Belongs to the UPF0435 family
LEHADEAE_01170 8.1e-192 ydiM EGP Major facilitator Superfamily
LEHADEAE_01171 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LEHADEAE_01172 1.9e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEHADEAE_01173 9.8e-186 K helix_turn _helix lactose operon repressor
LEHADEAE_01174 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
LEHADEAE_01175 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
LEHADEAE_01176 1.6e-197 yibE S YibE/F-like protein
LEHADEAE_01177 3.3e-122 yibF S YibE/F-like protein
LEHADEAE_01178 1.2e-123 yfkO C nitroreductase
LEHADEAE_01179 3.4e-129 treR K transcriptional
LEHADEAE_01180 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LEHADEAE_01181 2.8e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEHADEAE_01182 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
LEHADEAE_01183 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
LEHADEAE_01184 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
LEHADEAE_01185 2.3e-63 yhdN S Domain of unknown function (DUF1992)
LEHADEAE_01186 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LEHADEAE_01187 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
LEHADEAE_01188 1.5e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LEHADEAE_01189 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
LEHADEAE_01190 3.1e-50 yflH S Protein of unknown function (DUF3243)
LEHADEAE_01191 7e-19 yflI
LEHADEAE_01192 1.5e-14 yflJ S Protein of unknown function (DUF2639)
LEHADEAE_01193 1.3e-122 yflK S protein conserved in bacteria
LEHADEAE_01194 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LEHADEAE_01195 2.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LEHADEAE_01196 7.4e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
LEHADEAE_01197 3.6e-225 citM C Citrate transporter
LEHADEAE_01198 3e-176 yflP S Tripartite tricarboxylate transporter family receptor
LEHADEAE_01199 2.6e-118 citT T response regulator
LEHADEAE_01200 3.7e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LEHADEAE_01201 4e-63 srtA 3.4.22.70 M Sortase family
LEHADEAE_01202 9.2e-117 M cell wall anchor domain
LEHADEAE_01203 1.6e-151 M1-574 T Transcriptional regulatory protein, C terminal
LEHADEAE_01204 0.0 ywpD T PhoQ Sensor
LEHADEAE_01205 3.5e-73 M1-820 Q Collagen triple helix repeat (20 copies)
LEHADEAE_01206 3.9e-50 Q calcium- and calmodulin-responsive adenylate cyclase activity
LEHADEAE_01208 1.7e-38 Q Collagen triple helix repeat (20 copies)
LEHADEAE_01209 5.2e-27 Q PFAM Collagen triple helix
LEHADEAE_01210 6e-234 yflS P Sodium:sulfate symporter transmembrane region
LEHADEAE_01211 1e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
LEHADEAE_01212 1.3e-57 yflT S Heat induced stress protein YflT
LEHADEAE_01213 2.7e-24 S Protein of unknown function (DUF3212)
LEHADEAE_01214 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
LEHADEAE_01215 2.1e-41 yfmK 2.3.1.128 K acetyltransferase
LEHADEAE_01216 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
LEHADEAE_01217 3.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEHADEAE_01218 7.5e-206 yfmO EGP Major facilitator Superfamily
LEHADEAE_01219 1.8e-69 yfmP K transcriptional
LEHADEAE_01220 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEHADEAE_01221 1.2e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEHADEAE_01222 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
LEHADEAE_01223 7.5e-107 yfmS NT chemotaxis protein
LEHADEAE_01224 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEHADEAE_01225 3e-246 yfnA E amino acid
LEHADEAE_01226 1.5e-217 fsr P COG0477 Permeases of the major facilitator superfamily
LEHADEAE_01227 2.6e-185 yfnD M Nucleotide-diphospho-sugar transferase
LEHADEAE_01228 6.2e-221 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
LEHADEAE_01229 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
LEHADEAE_01230 7.1e-172 yfnG 4.2.1.45 M dehydratase
LEHADEAE_01231 1.8e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
LEHADEAE_01232 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LEHADEAE_01233 2.1e-143 2.1.1.163, 2.1.1.201 Q methyltransferase
LEHADEAE_01234 2.8e-112 S CAAX protease self-immunity
LEHADEAE_01235 8.6e-153 sagB C Nitroreductase family
LEHADEAE_01236 1.1e-261 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
LEHADEAE_01237 9.8e-183 S ATP diphosphatase activity
LEHADEAE_01238 6.6e-125
LEHADEAE_01239 8.1e-70 S protein homooligomerization
LEHADEAE_01240 4.8e-126 V ABC-2 type transporter
LEHADEAE_01241 1.5e-161 V ATPases associated with a variety of cellular activities
LEHADEAE_01242 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
LEHADEAE_01244 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LEHADEAE_01245 2.2e-196 yetN S Protein of unknown function (DUF3900)
LEHADEAE_01246 6e-205 yetM CH FAD binding domain
LEHADEAE_01247 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
LEHADEAE_01249 1.1e-105 yetJ S Belongs to the BI1 family
LEHADEAE_01250 5.3e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
LEHADEAE_01251 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
LEHADEAE_01252 3.7e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEHADEAE_01253 3.2e-07 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEHADEAE_01254 2e-42 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEHADEAE_01255 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LEHADEAE_01256 2.1e-120 yetF S membrane
LEHADEAE_01258 2e-94 yesJ K Acetyltransferase (GNAT) family
LEHADEAE_01259 8.9e-104 cotJC P Spore Coat
LEHADEAE_01260 1.3e-44 cotJB S CotJB protein
LEHADEAE_01261 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
LEHADEAE_01262 9.1e-97 aadK G Streptomycin adenylyltransferase
LEHADEAE_01264 9.4e-127 yeeN K transcriptional regulatory protein
LEHADEAE_01265 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
LEHADEAE_01266 1.1e-57 S Protein of unknown function, DUF600
LEHADEAE_01267 1.6e-76 S Protein of unknown function, DUF600
LEHADEAE_01268 1.7e-55 S Protein of unknown function, DUF600
LEHADEAE_01269 1.1e-46 S Protein of unknown function, DUF600
LEHADEAE_01270 6.9e-54 S Protein of unknown function, DUF600
LEHADEAE_01271 2.2e-138 cylB V ABC-2 type transporter
LEHADEAE_01272 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
LEHADEAE_01273 4.5e-21
LEHADEAE_01274 6.4e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LEHADEAE_01275 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LEHADEAE_01276 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LEHADEAE_01277 1.9e-150 yerO K Transcriptional regulator
LEHADEAE_01278 3.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEHADEAE_01279 3.9e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LEHADEAE_01280 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LEHADEAE_01281 4.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEHADEAE_01282 1.3e-120 sapB S MgtC SapB transporter
LEHADEAE_01283 6.1e-193 yerI S homoserine kinase type II (protein kinase fold)
LEHADEAE_01284 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
LEHADEAE_01285 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LEHADEAE_01286 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LEHADEAE_01287 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LEHADEAE_01288 4.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
LEHADEAE_01289 2.4e-50 yerC S protein conserved in bacteria
LEHADEAE_01290 1.5e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
LEHADEAE_01291 0.0 yerA 3.5.4.2 F adenine deaminase
LEHADEAE_01292 2.6e-25 S Protein of unknown function (DUF2892)
LEHADEAE_01293 2.7e-233 purD 6.3.4.13 F Belongs to the GARS family
LEHADEAE_01294 5e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LEHADEAE_01295 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LEHADEAE_01296 1.1e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LEHADEAE_01297 1.2e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LEHADEAE_01298 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEHADEAE_01299 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEHADEAE_01300 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LEHADEAE_01301 3.8e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LEHADEAE_01302 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LEHADEAE_01303 3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LEHADEAE_01304 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LEHADEAE_01305 5.5e-29 yebG S NETI protein
LEHADEAE_01306 7.5e-92 yebE S UPF0316 protein
LEHADEAE_01308 1.5e-125 yebC M Membrane
LEHADEAE_01309 8.1e-209 pbuG S permease
LEHADEAE_01310 3.5e-250 S Domain of unknown function (DUF4179)
LEHADEAE_01311 5e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LEHADEAE_01312 2.4e-192 2.7.7.49 L DNA polymerase
LEHADEAE_01313 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LEHADEAE_01314 0.0 yebA E COG1305 Transglutaminase-like enzymes
LEHADEAE_01315 1.7e-205 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LEHADEAE_01316 4.3e-175 yeaC S COG0714 MoxR-like ATPases
LEHADEAE_01317 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
LEHADEAE_01318 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
LEHADEAE_01319 7.2e-35 ydjO S Cold-inducible protein YdjO
LEHADEAE_01321 2.3e-134 ydjN U Involved in the tonB-independent uptake of proteins
LEHADEAE_01322 1.2e-61 ydjM M Lytic transglycolase
LEHADEAE_01323 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
LEHADEAE_01324 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LEHADEAE_01325 1.4e-145 rsiV S Protein of unknown function (DUF3298)
LEHADEAE_01326 0.0 yrhL I Acyltransferase family
LEHADEAE_01327 3.1e-144 ydjI S virion core protein (lumpy skin disease virus)
LEHADEAE_01328 3.8e-118 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
LEHADEAE_01329 1.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEHADEAE_01330 1.3e-112 pspA KT Phage shock protein A
LEHADEAE_01331 3.1e-29 yjdJ S Domain of unknown function (DUF4306)
LEHADEAE_01332 4.9e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
LEHADEAE_01333 4.1e-248 gutA G MFS/sugar transport protein
LEHADEAE_01334 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
LEHADEAE_01335 0.0 K NB-ARC domain
LEHADEAE_01336 1.7e-33 yvfS V Transporter
LEHADEAE_01337 1.6e-78 yvfR V ABC transporter
LEHADEAE_01338 1e-07 moeB 2.7.7.73, 2.7.7.80 H molybdopterin biosynthesis protein moeB
LEHADEAE_01339 1.8e-28 C Nitroreductase family
LEHADEAE_01340 4.3e-39 cobT 1.13.11.79, 2.4.2.21 C coenzyme F420-1:gamma-L-glutamate ligase activity
LEHADEAE_01341 2e-102 H YcaO cyclodehydratase, ATP-ad Mg2+-binding
LEHADEAE_01343 4.1e-25 C coenzyme F420-1:gamma-L-glutamate ligase activity
LEHADEAE_01344 3.9e-50 S Lantibiotic dehydratase, C terminus
LEHADEAE_01345 9.1e-71 E Peptidase dimerisation domain
LEHADEAE_01346 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LEHADEAE_01347 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LEHADEAE_01348 4.3e-127 ydiL S CAAX protease self-immunity
LEHADEAE_01349 1.7e-27 ydiK S Domain of unknown function (DUF4305)
LEHADEAE_01350 1.8e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEHADEAE_01351 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LEHADEAE_01352 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LEHADEAE_01353 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LEHADEAE_01354 0.0 ydiF S ABC transporter
LEHADEAE_01355 6.2e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LEHADEAE_01356 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LEHADEAE_01357 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
LEHADEAE_01358 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
LEHADEAE_01359 6.7e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LEHADEAE_01361 7.8e-08
LEHADEAE_01362 3.4e-39 S COG NOG14552 non supervised orthologous group
LEHADEAE_01365 1.2e-250 iolT EGP Major facilitator Superfamily
LEHADEAE_01366 1.7e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
LEHADEAE_01367 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
LEHADEAE_01368 1.9e-163 ydhU P Catalase
LEHADEAE_01369 3.5e-296 yveA E amino acid
LEHADEAE_01370 2.9e-102 yvdT K Transcriptional regulator
LEHADEAE_01371 2.3e-51 ykkC P Small Multidrug Resistance protein
LEHADEAE_01372 2.6e-49 sugE P Small Multidrug Resistance protein
LEHADEAE_01373 8.2e-216 yeaN P COG2807 Cyanate permease
LEHADEAE_01374 9.9e-118 K FCD
LEHADEAE_01375 1.5e-132 ydhQ K UTRA
LEHADEAE_01376 2.9e-194 pbuE EGP Major facilitator Superfamily
LEHADEAE_01377 5.5e-98 ydhK M Protein of unknown function (DUF1541)
LEHADEAE_01379 1.2e-260 pbpE V Beta-lactamase
LEHADEAE_01382 9.2e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LEHADEAE_01383 6.9e-119 ydhC K FCD
LEHADEAE_01384 1e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
LEHADEAE_01385 2.3e-143 ycgJ_1 Q ubiE/COQ5 methyltransferase family
LEHADEAE_01386 1.3e-111 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
LEHADEAE_01387 1.8e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LEHADEAE_01388 2.2e-148 bltR K helix_turn_helix, mercury resistance
LEHADEAE_01389 2.2e-81 bltD 2.3.1.57 K FR47-like protein
LEHADEAE_01390 9.4e-122 ydhB S membrane transporter protein
LEHADEAE_01391 5e-156 K Helix-turn-helix XRE-family like proteins
LEHADEAE_01392 1.1e-223 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEHADEAE_01393 1.8e-210 tcaB EGP Major facilitator Superfamily
LEHADEAE_01394 5e-196 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
LEHADEAE_01395 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
LEHADEAE_01396 5.7e-97 ynaD J Acetyltransferase (GNAT) domain
LEHADEAE_01397 5.2e-298 expZ S ABC transporter
LEHADEAE_01398 3.3e-132 puuD S Peptidase C26
LEHADEAE_01399 0.0 ydfJ S drug exporters of the RND superfamily
LEHADEAE_01400 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEHADEAE_01401 3.9e-216 ydfH 2.7.13.3 T Histidine kinase
LEHADEAE_01402 1.3e-35 yraG
LEHADEAE_01403 8.4e-63 yraF M Spore coat protein
LEHADEAE_01404 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEHADEAE_01405 5.4e-24 yraE
LEHADEAE_01406 1.4e-47 yraD M Spore coat protein
LEHADEAE_01407 1.6e-100 ydeS K Transcriptional regulator
LEHADEAE_01408 6.7e-178 ydeR EGP Major facilitator Superfamily
LEHADEAE_01410 2.3e-113 paiB K Transcriptional regulator
LEHADEAE_01411 4.1e-256 K helix_turn_helix gluconate operon transcriptional repressor
LEHADEAE_01412 2.3e-224 mleN_2 C antiporter
LEHADEAE_01413 1.8e-66 yraB K helix_turn_helix, mercury resistance
LEHADEAE_01414 1.1e-200 adhA 1.1.1.1 C alcohol dehydrogenase
LEHADEAE_01415 8.4e-163 S Sodium Bile acid symporter family
LEHADEAE_01416 2.6e-51 ydeH
LEHADEAE_01417 6.9e-195 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
LEHADEAE_01419 3.3e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
LEHADEAE_01420 1.8e-14 ykkA S Protein of unknown function (DUF664)
LEHADEAE_01423 3.4e-194 trkA P Oxidoreductase
LEHADEAE_01424 6.4e-168 czcD P COG1230 Co Zn Cd efflux system component
LEHADEAE_01425 1.2e-09 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEHADEAE_01426 1.9e-266 ygaK C COG0277 FAD FMN-containing dehydrogenases
LEHADEAE_01429 5.1e-44 G Cupin domain
LEHADEAE_01430 5.5e-83 S DinB superfamily
LEHADEAE_01431 5.2e-181 S Patatin-like phospholipase
LEHADEAE_01432 2.4e-50 K Transcriptional regulator PadR-like family
LEHADEAE_01433 5.7e-103 S Protein of unknown function (DUF2812)
LEHADEAE_01434 3.7e-117 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LEHADEAE_01435 1.1e-117 yrkJ S membrane transporter protein
LEHADEAE_01436 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
LEHADEAE_01437 1.2e-200 yrkH P Rhodanese Homology Domain
LEHADEAE_01438 5e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
LEHADEAE_01439 6.2e-82 yrkE O DsrE/DsrF/DrsH-like family
LEHADEAE_01440 9.2e-40 yrkD S protein conserved in bacteria
LEHADEAE_01441 1.4e-30 cspL K Cold shock
LEHADEAE_01442 5.4e-110 ywnB S NAD(P)H-binding
LEHADEAE_01443 1.6e-71 ywnA K Transcriptional regulator
LEHADEAE_01444 8.2e-49 ohrR K Transcriptional regulator
LEHADEAE_01445 4.7e-46 ohrB O OsmC-like protein
LEHADEAE_01446 1e-136 I esterase
LEHADEAE_01447 9.8e-229 proP EGP Transporter
LEHADEAE_01448 2.3e-150 S Serine aminopeptidase, S33
LEHADEAE_01449 1.1e-95 ywrO S Flavodoxin-like fold
LEHADEAE_01458 1.6e-08
LEHADEAE_01461 2.9e-19 C Na+/H+ antiporter family
LEHADEAE_01462 2.4e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
LEHADEAE_01463 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LEHADEAE_01464 9e-264 ygaK C Berberine and berberine like
LEHADEAE_01466 4.4e-231 oppA5 E PFAM extracellular solute-binding protein family 5
LEHADEAE_01467 9.2e-138 appB P Binding-protein-dependent transport system inner membrane component
LEHADEAE_01468 1.2e-126 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEHADEAE_01469 1.3e-134 oppD3 P Belongs to the ABC transporter superfamily
LEHADEAE_01470 5.3e-133 oppF3 E Belongs to the ABC transporter superfamily
LEHADEAE_01471 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LEHADEAE_01472 6.6e-181 S Amidohydrolase
LEHADEAE_01473 1.8e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LEHADEAE_01474 1.7e-179 ssuA M Sulfonate ABC transporter
LEHADEAE_01475 3.7e-143 ssuC P ABC transporter (permease)
LEHADEAE_01476 3.8e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
LEHADEAE_01477 1.6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEHADEAE_01478 8.6e-81 ygaO
LEHADEAE_01479 4.8e-23 K Transcriptional regulator
LEHADEAE_01481 3.2e-107 yhzB S B3/4 domain
LEHADEAE_01482 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LEHADEAE_01483 2e-172 yhbB S Putative amidase domain
LEHADEAE_01484 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LEHADEAE_01485 3e-108 yhbD K Protein of unknown function (DUF4004)
LEHADEAE_01486 4.7e-62 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
LEHADEAE_01487 9.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
LEHADEAE_01489 0.0 prkA T Ser protein kinase
LEHADEAE_01490 3.9e-215 yhbH S Belongs to the UPF0229 family
LEHADEAE_01491 4.6e-74 yhbI K DNA-binding transcription factor activity
LEHADEAE_01492 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
LEHADEAE_01493 8.4e-285 yhcA EGP Major facilitator Superfamily
LEHADEAE_01494 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
LEHADEAE_01495 3.8e-55 yhcC
LEHADEAE_01496 1.6e-52
LEHADEAE_01497 2.8e-61 yhcF K Transcriptional regulator
LEHADEAE_01498 1.3e-123 yhcG V ABC transporter, ATP-binding protein
LEHADEAE_01499 7.7e-166 yhcH V ABC transporter, ATP-binding protein
LEHADEAE_01500 8.2e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LEHADEAE_01501 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
LEHADEAE_01502 8.3e-143 metQ M Belongs to the nlpA lipoprotein family
LEHADEAE_01503 2.5e-184 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
LEHADEAE_01504 1.1e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEHADEAE_01505 2.1e-50 yhcM
LEHADEAE_01506 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEHADEAE_01507 2.2e-160 yhcP
LEHADEAE_01508 8.4e-114 yhcQ M Spore coat protein
LEHADEAE_01509 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
LEHADEAE_01510 2.2e-105 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LEHADEAE_01511 4e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEHADEAE_01512 1.3e-69 yhcU S Family of unknown function (DUF5365)
LEHADEAE_01513 9.9e-68 yhcV S COG0517 FOG CBS domain
LEHADEAE_01514 1.9e-124 yhcW 5.4.2.6 S hydrolase
LEHADEAE_01515 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LEHADEAE_01516 2.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEHADEAE_01517 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LEHADEAE_01518 7.7e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
LEHADEAE_01519 1.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LEHADEAE_01520 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LEHADEAE_01521 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LEHADEAE_01522 1.5e-203 yhcY 2.7.13.3 T Histidine kinase
LEHADEAE_01523 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LEHADEAE_01525 1.8e-69 azr 1.7.1.6 S NADPH-dependent FMN reductase
LEHADEAE_01526 2.5e-39 yhdB S YhdB-like protein
LEHADEAE_01527 5.3e-53 yhdC S Protein of unknown function (DUF3889)
LEHADEAE_01528 2.9e-215 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LEHADEAE_01529 1.6e-73 nsrR K Transcriptional regulator
LEHADEAE_01530 3.4e-243 ygxB M Conserved TM helix
LEHADEAE_01531 5.1e-270 ycgB S Stage V sporulation protein R
LEHADEAE_01532 4.9e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LEHADEAE_01533 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LEHADEAE_01534 1.3e-162 citR K Transcriptional regulator
LEHADEAE_01535 4.1e-104 citA 2.3.3.1 C Belongs to the citrate synthase family
LEHADEAE_01536 2.3e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEHADEAE_01537 1.2e-250 yhdG E amino acid
LEHADEAE_01538 2.9e-198 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LEHADEAE_01539 8.1e-45 yhdK S Sigma-M inhibitor protein
LEHADEAE_01540 1.3e-201 yhdL S Sigma factor regulator N-terminal
LEHADEAE_01541 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
LEHADEAE_01542 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LEHADEAE_01543 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LEHADEAE_01544 2.8e-70 cueR K transcriptional
LEHADEAE_01545 1.9e-225 yhdR 2.6.1.1 E Aminotransferase
LEHADEAE_01546 1.1e-234 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEHADEAE_01547 1.3e-254 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
LEHADEAE_01548 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEHADEAE_01549 2e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LEHADEAE_01550 7.2e-127 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEHADEAE_01552 3.5e-205 yhdY M Mechanosensitive ion channel
LEHADEAE_01553 1.2e-137 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LEHADEAE_01554 1.1e-155 yheN G deacetylase
LEHADEAE_01555 3.4e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LEHADEAE_01556 3e-87 pksA K Transcriptional regulator
LEHADEAE_01557 1.8e-93 ymcC S Membrane
LEHADEAE_01558 6.2e-85 T universal stress protein
LEHADEAE_01560 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEHADEAE_01561 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
LEHADEAE_01562 1.6e-111 yheG GM NAD(P)H-binding
LEHADEAE_01564 1.3e-28 sspB S spore protein
LEHADEAE_01565 1.7e-36 yheE S Family of unknown function (DUF5342)
LEHADEAE_01566 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
LEHADEAE_01567 3.4e-213 yheC HJ YheC/D like ATP-grasp
LEHADEAE_01568 3.6e-205 yheB S Belongs to the UPF0754 family
LEHADEAE_01569 4.4e-53 yheA S Belongs to the UPF0342 family
LEHADEAE_01570 1.4e-201 yhaZ L DNA alkylation repair enzyme
LEHADEAE_01571 4.7e-157 yhaX S haloacid dehalogenase-like hydrolase
LEHADEAE_01572 2.7e-293 hemZ H coproporphyrinogen III oxidase
LEHADEAE_01573 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
LEHADEAE_01574 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
LEHADEAE_01575 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
LEHADEAE_01577 2e-135 yhaR 5.3.3.18 I enoyl-CoA hydratase
LEHADEAE_01578 2.8e-14 S YhzD-like protein
LEHADEAE_01579 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
LEHADEAE_01580 2.7e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
LEHADEAE_01581 4.7e-235 yhaO L DNA repair exonuclease
LEHADEAE_01582 0.0 yhaN L AAA domain
LEHADEAE_01583 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
LEHADEAE_01584 1.8e-31 yhaL S Sporulation protein YhaL
LEHADEAE_01585 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LEHADEAE_01586 7e-95 yhaK S Putative zincin peptidase
LEHADEAE_01587 9.9e-55 yhaI S Protein of unknown function (DUF1878)
LEHADEAE_01588 8.6e-113 hpr K Negative regulator of protease production and sporulation
LEHADEAE_01589 6.2e-39 yhaH S YtxH-like protein
LEHADEAE_01590 2e-17
LEHADEAE_01591 1.4e-76 trpP S Tryptophan transporter TrpP
LEHADEAE_01592 3e-201 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LEHADEAE_01593 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LEHADEAE_01594 1.1e-135 ecsA V transporter (ATP-binding protein)
LEHADEAE_01595 1.5e-220 ecsB U ABC transporter
LEHADEAE_01596 4e-122 ecsC S EcsC protein family
LEHADEAE_01597 2e-222 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LEHADEAE_01598 8.1e-244 yhfA C membrane
LEHADEAE_01599 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LEHADEAE_01600 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEHADEAE_01601 9.5e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LEHADEAE_01602 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LEHADEAE_01603 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LEHADEAE_01605 3.2e-101 yhgD K Transcriptional regulator
LEHADEAE_01606 4.7e-244 yhgE S YhgE Pip N-terminal domain protein
LEHADEAE_01607 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEHADEAE_01609 6.6e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
LEHADEAE_01610 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEHADEAE_01611 7.9e-11 yhfH S YhfH-like protein
LEHADEAE_01612 2.2e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LEHADEAE_01613 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
LEHADEAE_01614 7.9e-109 yhfK GM NmrA-like family
LEHADEAE_01615 4.1e-297 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LEHADEAE_01616 1.9e-65 yhfM
LEHADEAE_01617 5.3e-234 yhfN 3.4.24.84 O Peptidase M48
LEHADEAE_01618 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
LEHADEAE_01619 3.7e-149 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LEHADEAE_01620 1.7e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
LEHADEAE_01621 9.7e-200 vraB 2.3.1.9 I Belongs to the thiolase family
LEHADEAE_01622 1.6e-279 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LEHADEAE_01623 2.6e-87 bioY S BioY family
LEHADEAE_01624 3.1e-197 hemAT NT chemotaxis protein
LEHADEAE_01625 1.3e-295 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LEHADEAE_01626 3.2e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEHADEAE_01627 5.4e-31 yhzC S IDEAL
LEHADEAE_01628 1.9e-109 comK K Competence transcription factor
LEHADEAE_01629 4.7e-66 frataxin S Domain of unknown function (DU1801)
LEHADEAE_01630 1.4e-62 frataxin S Domain of unknown function (DU1801)
LEHADEAE_01631 8.7e-125 yrpD S Domain of unknown function, YrpD
LEHADEAE_01632 1.6e-42 yhjA S Excalibur calcium-binding domain
LEHADEAE_01633 3.3e-47 S Belongs to the UPF0145 family
LEHADEAE_01634 6.5e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEHADEAE_01635 3.1e-27 yhjC S Protein of unknown function (DUF3311)
LEHADEAE_01636 1.7e-60 yhjD
LEHADEAE_01637 1.5e-67 yhjE S SNARE associated Golgi protein
LEHADEAE_01638 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
LEHADEAE_01640 9.2e-270 yhjG CH FAD binding domain
LEHADEAE_01641 8.4e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
LEHADEAE_01642 1.8e-188 abrB S membrane
LEHADEAE_01643 6.6e-202 blt EGP Major facilitator Superfamily
LEHADEAE_01644 1.1e-107 K QacR-like protein, C-terminal region
LEHADEAE_01645 6.3e-93 yhjR S Rubrerythrin
LEHADEAE_01646 2.5e-119 ydfS S Protein of unknown function (DUF421)
LEHADEAE_01647 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
LEHADEAE_01648 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LEHADEAE_01649 9.7e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LEHADEAE_01650 0.0 sbcC L COG0419 ATPase involved in DNA repair
LEHADEAE_01651 1.3e-50 yisB V COG1403 Restriction endonuclease
LEHADEAE_01652 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
LEHADEAE_01653 1.1e-63 gerPE S Spore germination protein GerPE
LEHADEAE_01654 3.1e-23 gerPD S Spore germination protein
LEHADEAE_01655 1.4e-62 gerPC S Spore germination protein
LEHADEAE_01656 1.8e-34 gerPB S cell differentiation
LEHADEAE_01657 8.4e-34 gerPA S Spore germination protein
LEHADEAE_01658 4.8e-07 yisI S Spo0E like sporulation regulatory protein
LEHADEAE_01659 7.8e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LEHADEAE_01660 3.2e-59 yisL S UPF0344 protein
LEHADEAE_01661 3.4e-97 yisN S Protein of unknown function (DUF2777)
LEHADEAE_01662 0.0 asnO 6.3.5.4 E Asparagine synthase
LEHADEAE_01663 1.9e-130 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
LEHADEAE_01664 1.5e-245 yisQ V Mate efflux family protein
LEHADEAE_01665 5.9e-160 yisR K Transcriptional regulator
LEHADEAE_01666 6e-143 purR K helix_turn _helix lactose operon repressor
LEHADEAE_01667 5.8e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
LEHADEAE_01668 3.4e-83 yisT S DinB family
LEHADEAE_01669 7.8e-69 mcbG S Pentapeptide repeats (9 copies)
LEHADEAE_01670 2.4e-80 yjcF S Acetyltransferase (GNAT) domain
LEHADEAE_01671 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LEHADEAE_01672 6.6e-55 yajQ S Belongs to the UPF0234 family
LEHADEAE_01673 7.6e-160 cvfB S protein conserved in bacteria
LEHADEAE_01674 5.8e-172 yufN S ABC transporter substrate-binding protein PnrA-like
LEHADEAE_01675 1e-232 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LEHADEAE_01677 2.1e-157 yitS S protein conserved in bacteria
LEHADEAE_01678 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
LEHADEAE_01679 5.5e-80 ipi S Intracellular proteinase inhibitor
LEHADEAE_01680 4.4e-26 S Protein of unknown function (DUF3813)
LEHADEAE_01681 3.5e-07
LEHADEAE_01682 1.1e-152 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LEHADEAE_01683 3.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
LEHADEAE_01684 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
LEHADEAE_01685 4.6e-73 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LEHADEAE_01686 2.5e-272 yitY C D-arabinono-1,4-lactone oxidase
LEHADEAE_01687 1.2e-89 norB G Major Facilitator Superfamily
LEHADEAE_01688 6.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LEHADEAE_01689 1.5e-225 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LEHADEAE_01690 7.8e-135 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
LEHADEAE_01691 1.2e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LEHADEAE_01692 1.3e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEHADEAE_01693 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
LEHADEAE_01694 6.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LEHADEAE_01695 3.6e-27 yjzC S YjzC-like protein
LEHADEAE_01696 3.3e-23 yjzD S Protein of unknown function (DUF2929)
LEHADEAE_01697 8.4e-139 yjaU I carboxylic ester hydrolase activity
LEHADEAE_01698 8.8e-104 yjaV
LEHADEAE_01699 8e-165 med S Transcriptional activator protein med
LEHADEAE_01700 1.1e-26 comZ S ComZ
LEHADEAE_01701 5.4e-25 yjzB
LEHADEAE_01702 1.6e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LEHADEAE_01703 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LEHADEAE_01704 5.6e-149 yjaZ O Zn-dependent protease
LEHADEAE_01705 4.8e-182 appD P Belongs to the ABC transporter superfamily
LEHADEAE_01706 5.9e-188 appF E Belongs to the ABC transporter superfamily
LEHADEAE_01707 4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
LEHADEAE_01708 1.2e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEHADEAE_01709 6.1e-155 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEHADEAE_01710 1.7e-86 2.1.1.265 H Tellurite resistance protein TehB
LEHADEAE_01711 2.1e-140 EGP Transmembrane secretion effector
LEHADEAE_01712 1.2e-145 yjbA S Belongs to the UPF0736 family
LEHADEAE_01713 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LEHADEAE_01714 0.0 oppA E ABC transporter substrate-binding protein
LEHADEAE_01715 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEHADEAE_01716 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEHADEAE_01717 2.7e-202 oppD P Belongs to the ABC transporter superfamily
LEHADEAE_01718 2.3e-170 oppF E Belongs to the ABC transporter superfamily
LEHADEAE_01719 9.8e-230 S Putative glycosyl hydrolase domain
LEHADEAE_01720 1.3e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEHADEAE_01721 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LEHADEAE_01722 4.7e-109 yjbE P Integral membrane protein TerC family
LEHADEAE_01723 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LEHADEAE_01724 3.2e-217 yjbF S Competence protein
LEHADEAE_01725 0.0 pepF E oligoendopeptidase F
LEHADEAE_01726 5.8e-19
LEHADEAE_01727 2.3e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LEHADEAE_01728 4.8e-72 yjbI S Bacterial-like globin
LEHADEAE_01729 5.5e-116 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LEHADEAE_01730 4e-96 yjbK S protein conserved in bacteria
LEHADEAE_01731 6e-61 yjbL S Belongs to the UPF0738 family
LEHADEAE_01732 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
LEHADEAE_01733 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEHADEAE_01734 1.1e-164 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEHADEAE_01735 2.6e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LEHADEAE_01736 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LEHADEAE_01737 9.9e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LEHADEAE_01738 2.1e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
LEHADEAE_01739 1.4e-209 thiO 1.4.3.19 E Glycine oxidase
LEHADEAE_01740 6.7e-30 thiS H Thiamine biosynthesis
LEHADEAE_01741 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LEHADEAE_01742 1.1e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LEHADEAE_01743 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LEHADEAE_01744 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LEHADEAE_01745 1.2e-87 yjbX S Spore coat protein
LEHADEAE_01746 6.7e-83 cotZ S Spore coat protein
LEHADEAE_01747 4.6e-93 cotY S Spore coat protein Z
LEHADEAE_01748 5.1e-71 cotX S Spore Coat Protein X and V domain
LEHADEAE_01749 6.8e-21 cotW
LEHADEAE_01750 1.4e-52 cotV S Spore Coat Protein X and V domain
LEHADEAE_01751 1.6e-55 yjcA S Protein of unknown function (DUF1360)
LEHADEAE_01755 3.8e-38 spoVIF S Stage VI sporulation protein F
LEHADEAE_01756 0.0 yjcD 3.6.4.12 L DNA helicase
LEHADEAE_01757 1.3e-35
LEHADEAE_01758 1.3e-139 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
LEHADEAE_01759 5.7e-124 S ABC-2 type transporter
LEHADEAE_01760 1.3e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
LEHADEAE_01761 2.7e-35 K SpoVT / AbrB like domain
LEHADEAE_01763 2.3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEHADEAE_01764 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
LEHADEAE_01765 3.6e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
LEHADEAE_01766 8.7e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LEHADEAE_01767 2.2e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LEHADEAE_01769 2.6e-21
LEHADEAE_01770 9.1e-227 yobL S Bacterial EndoU nuclease
LEHADEAE_01772 8.5e-58 E Glyoxalase-like domain
LEHADEAE_01773 1.4e-162 bla 3.5.2.6 V beta-lactamase
LEHADEAE_01774 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
LEHADEAE_01775 2.9e-249 yfjF EGP Belongs to the major facilitator superfamily
LEHADEAE_01776 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
LEHADEAE_01777 5.6e-219 ganA 3.2.1.89 G arabinogalactan
LEHADEAE_01778 3.2e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LEHADEAE_01779 2.1e-185 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LEHADEAE_01780 1.3e-213 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LEHADEAE_01781 1.7e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LEHADEAE_01782 2.6e-49 lacF 2.7.1.207 G phosphotransferase system
LEHADEAE_01783 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
LEHADEAE_01784 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
LEHADEAE_01785 2.3e-122 5.4.2.6 S Haloacid dehalogenase-like hydrolase
LEHADEAE_01787 2.4e-105 yhiD S MgtC SapB transporter
LEHADEAE_01788 3.7e-21 yjfB S Putative motility protein
LEHADEAE_01789 2.3e-66 T PhoQ Sensor
LEHADEAE_01790 1.3e-99 yjgB S Domain of unknown function (DUF4309)
LEHADEAE_01791 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
LEHADEAE_01792 4.3e-92 yjgD S Protein of unknown function (DUF1641)
LEHADEAE_01793 4.4e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
LEHADEAE_01794 1.6e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LEHADEAE_01795 6.8e-29
LEHADEAE_01796 5.1e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LEHADEAE_01797 2.1e-124 ybbM S transport system, permease component
LEHADEAE_01798 7.1e-130 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
LEHADEAE_01799 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
LEHADEAE_01800 5.7e-91 yjlB S Cupin domain
LEHADEAE_01801 7e-66 yjlC S Protein of unknown function (DUF1641)
LEHADEAE_01802 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
LEHADEAE_01803 1.8e-275 uxaC 5.3.1.12 G glucuronate isomerase
LEHADEAE_01804 6.7e-254 yjmB G symporter YjmB
LEHADEAE_01805 1.2e-180 exuR K transcriptional
LEHADEAE_01806 7.3e-280 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
LEHADEAE_01807 2.7e-152 uxaA 4.2.1.7, 4.4.1.24 G Altronate
LEHADEAE_01808 3.4e-106 uxaA 4.2.1.7, 4.4.1.24 G Altronate
LEHADEAE_01809 4e-87 T Transcriptional regulatory protein, C terminal
LEHADEAE_01810 1.4e-131 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LEHADEAE_01811 2.1e-15 V ABC transporter, ATP-binding protein
LEHADEAE_01813 2.5e-130 MA20_18170 S membrane transporter protein
LEHADEAE_01814 8.9e-78 yjoA S DinB family
LEHADEAE_01815 4.9e-215 S response regulator aspartate phosphatase
LEHADEAE_01817 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LEHADEAE_01818 8e-61 yjqA S Bacterial PH domain
LEHADEAE_01819 6.7e-110 yjqB S phage-related replication protein
LEHADEAE_01821 2.9e-110 xkdA E IrrE N-terminal-like domain
LEHADEAE_01822 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
LEHADEAE_01824 8.8e-150 xkdC L Bacterial dnaA protein
LEHADEAE_01827 2e-10 yqaO S Phage-like element PBSX protein XtrA
LEHADEAE_01828 8.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LEHADEAE_01829 4e-110 xtmA L phage terminase small subunit
LEHADEAE_01830 4.2e-210 xtmB S phage terminase, large subunit
LEHADEAE_01831 5.1e-241 yqbA S portal protein
LEHADEAE_01832 1.7e-87 yqbD 2.1.1.72 L Putative phage serine protease XkdF
LEHADEAE_01833 4.6e-158 xkdG S Phage capsid family
LEHADEAE_01834 3.3e-46 yqbG S Protein of unknown function (DUF3199)
LEHADEAE_01835 5.5e-43 yqbH S Domain of unknown function (DUF3599)
LEHADEAE_01836 2e-59 xkdI S Bacteriophage HK97-gp10, putative tail-component
LEHADEAE_01837 3.2e-56 xkdJ
LEHADEAE_01838 8.2e-15
LEHADEAE_01839 7.7e-226 xkdK S Phage tail sheath C-terminal domain
LEHADEAE_01840 2e-74 xkdM S Phage tail tube protein
LEHADEAE_01841 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
LEHADEAE_01842 3.4e-19
LEHADEAE_01843 2.5e-194 xkdO L Transglycosylase SLT domain
LEHADEAE_01844 6.6e-111 xkdP S Lysin motif
LEHADEAE_01845 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
LEHADEAE_01846 7.2e-32 xkdR S Protein of unknown function (DUF2577)
LEHADEAE_01847 4.2e-58 xkdS S Protein of unknown function (DUF2634)
LEHADEAE_01848 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LEHADEAE_01849 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
LEHADEAE_01850 3.6e-26
LEHADEAE_01851 1.7e-91
LEHADEAE_01853 2.3e-27 xkdX
LEHADEAE_01854 3.4e-135 xepA
LEHADEAE_01855 8.7e-38 xhlA S Haemolysin XhlA
LEHADEAE_01856 1.3e-38 xhlB S SPP1 phage holin
LEHADEAE_01857 1.6e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEHADEAE_01858 8.7e-23 spoIISB S Stage II sporulation protein SB
LEHADEAE_01859 5.9e-132 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
LEHADEAE_01860 5.8e-175 pit P phosphate transporter
LEHADEAE_01861 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
LEHADEAE_01862 9.4e-242 steT E amino acid
LEHADEAE_01863 1.2e-177 mhqA E COG0346 Lactoylglutathione lyase and related lyases
LEHADEAE_01864 1.1e-303 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LEHADEAE_01865 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEHADEAE_01866 1.5e-16 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LEHADEAE_01867 7.3e-205 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LEHADEAE_01868 6.3e-277 yubD P Major Facilitator Superfamily
LEHADEAE_01869 1.9e-155 dppA E D-aminopeptidase
LEHADEAE_01870 5.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEHADEAE_01871 6.1e-174 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LEHADEAE_01872 7.7e-191 dppD P Belongs to the ABC transporter superfamily
LEHADEAE_01873 0.0 dppE E ABC transporter substrate-binding protein
LEHADEAE_01874 3.7e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LEHADEAE_01875 5.9e-197 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LEHADEAE_01876 1.9e-169 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LEHADEAE_01877 1.6e-182 ykfD E Belongs to the ABC transporter superfamily
LEHADEAE_01878 3.3e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
LEHADEAE_01879 1.5e-158 ykgA E Amidinotransferase
LEHADEAE_01880 9.2e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
LEHADEAE_01881 3.1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LEHADEAE_01882 1.4e-51 ykkC P Multidrug resistance protein
LEHADEAE_01883 1e-48 ykkD P Multidrug resistance protein
LEHADEAE_01884 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LEHADEAE_01885 2.7e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEHADEAE_01886 1.1e-223 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LEHADEAE_01887 4.1e-69 ohrA O Organic hydroperoxide resistance protein
LEHADEAE_01888 1.1e-72 ohrR K COG1846 Transcriptional regulators
LEHADEAE_01889 4.2e-71 ohrB O Organic hydroperoxide resistance protein
LEHADEAE_01890 3.5e-55 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LEHADEAE_01892 3.8e-215 M Glycosyl transferase family 2
LEHADEAE_01893 9.3e-123 M PFAM Collagen triple helix repeat (20 copies)
LEHADEAE_01894 1.2e-214 hcaT 1.5.1.2 EGP Major facilitator Superfamily
LEHADEAE_01895 5.8e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LEHADEAE_01896 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LEHADEAE_01897 5e-176 isp O Belongs to the peptidase S8 family
LEHADEAE_01898 4.3e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEHADEAE_01899 2.1e-132 ykoC P Cobalt transport protein
LEHADEAE_01900 5e-301 P ABC transporter, ATP-binding protein
LEHADEAE_01901 1e-97 ykoE S ABC-type cobalt transport system, permease component
LEHADEAE_01902 3.3e-244 ydhD M Glycosyl hydrolase
LEHADEAE_01904 3e-235 mgtE P Acts as a magnesium transporter
LEHADEAE_01905 5.4e-53 tnrA K transcriptional
LEHADEAE_01906 1.9e-16
LEHADEAE_01907 3.1e-26 ykoL
LEHADEAE_01908 1.1e-80 ykoM K transcriptional
LEHADEAE_01909 3.7e-99 ykoP G polysaccharide deacetylase
LEHADEAE_01910 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
LEHADEAE_01911 4.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LEHADEAE_01912 3.8e-99 ykoX S membrane-associated protein
LEHADEAE_01913 8.6e-134 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LEHADEAE_01914 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEHADEAE_01915 1.5e-118 rsgI S Anti-sigma factor N-terminus
LEHADEAE_01916 2.5e-26 sspD S small acid-soluble spore protein
LEHADEAE_01917 8.6e-125 ykrK S Domain of unknown function (DUF1836)
LEHADEAE_01918 4.5e-155 htpX O Belongs to the peptidase M48B family
LEHADEAE_01919 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
LEHADEAE_01920 7.2e-113 ydfR S Protein of unknown function (DUF421)
LEHADEAE_01921 8.7e-23 ykzE
LEHADEAE_01922 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
LEHADEAE_01923 0.0 kinE 2.7.13.3 T Histidine kinase
LEHADEAE_01924 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LEHADEAE_01926 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LEHADEAE_01927 1.5e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LEHADEAE_01928 2.9e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LEHADEAE_01929 1.7e-226 mtnE 2.6.1.83 E Aminotransferase
LEHADEAE_01930 4.3e-225 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LEHADEAE_01931 2.7e-128 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LEHADEAE_01932 5.2e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LEHADEAE_01933 7.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LEHADEAE_01934 3.4e-10 S Spo0E like sporulation regulatory protein
LEHADEAE_01935 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
LEHADEAE_01936 5.5e-77 ykvE K transcriptional
LEHADEAE_01937 2.7e-127 motB N Flagellar motor protein
LEHADEAE_01938 3.3e-136 motA N flagellar motor
LEHADEAE_01939 0.0 clpE O Belongs to the ClpA ClpB family
LEHADEAE_01940 1.3e-182 ykvI S membrane
LEHADEAE_01941 1.4e-185
LEHADEAE_01942 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LEHADEAE_01943 1.7e-78 queD 4.1.2.50, 4.2.3.12 H synthase
LEHADEAE_01944 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LEHADEAE_01945 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LEHADEAE_01946 3.5e-45 ykvR S Protein of unknown function (DUF3219)
LEHADEAE_01947 7.8e-25 ykvS S protein conserved in bacteria
LEHADEAE_01948 3.9e-27
LEHADEAE_01949 6.9e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
LEHADEAE_01950 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEHADEAE_01951 1.7e-87 stoA CO thiol-disulfide
LEHADEAE_01952 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LEHADEAE_01953 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LEHADEAE_01955 3.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
LEHADEAE_01956 5.1e-156 glcT K antiterminator
LEHADEAE_01957 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEHADEAE_01958 2.1e-39 ptsH G phosphocarrier protein HPr
LEHADEAE_01959 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LEHADEAE_01960 6.1e-38 splA S Transcriptional regulator
LEHADEAE_01961 2.4e-192 splB 4.1.99.14 L Spore photoproduct lyase
LEHADEAE_01962 1.3e-263 mcpC NT chemotaxis protein
LEHADEAE_01963 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LEHADEAE_01964 7.4e-93 ykwD J protein with SCP PR1 domains
LEHADEAE_01965 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
LEHADEAE_01966 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
LEHADEAE_01967 4.3e-214 patA 2.6.1.1 E Aminotransferase
LEHADEAE_01968 2.3e-09
LEHADEAE_01969 5.3e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
LEHADEAE_01970 1.4e-83 ykyB S YkyB-like protein
LEHADEAE_01971 5.6e-239 ykuC EGP Major facilitator Superfamily
LEHADEAE_01972 4.1e-89 ykuD S protein conserved in bacteria
LEHADEAE_01973 1.4e-153 ykuE S Metallophosphoesterase
LEHADEAE_01974 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEHADEAE_01976 3.7e-232 ykuI T Diguanylate phosphodiesterase
LEHADEAE_01977 3.9e-37 ykuJ S protein conserved in bacteria
LEHADEAE_01978 1.4e-92 ykuK S Ribonuclease H-like
LEHADEAE_01979 2.1e-25 ykzF S Antirepressor AbbA
LEHADEAE_01980 1e-75 ykuL S CBS domain
LEHADEAE_01981 1.3e-167 ccpC K Transcriptional regulator
LEHADEAE_01982 3e-89 fld C Flavodoxin
LEHADEAE_01983 2.2e-165 ykuO
LEHADEAE_01984 6e-79 fld C Flavodoxin
LEHADEAE_01985 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LEHADEAE_01986 9.9e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LEHADEAE_01987 4.8e-38 ykuS S Belongs to the UPF0180 family
LEHADEAE_01988 1.9e-139 ykuT M Mechanosensitive ion channel
LEHADEAE_01989 7.4e-77 ykuV CO thiol-disulfide
LEHADEAE_01990 4.5e-98 rok K Repressor of ComK
LEHADEAE_01991 3.1e-160 yknT
LEHADEAE_01992 4.1e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LEHADEAE_01993 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LEHADEAE_01994 1.4e-242 moeA 2.10.1.1 H molybdopterin
LEHADEAE_01995 1.4e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
LEHADEAE_01996 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
LEHADEAE_01997 1.7e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LEHADEAE_01998 8.3e-104 yknW S Yip1 domain
LEHADEAE_01999 2.3e-167 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LEHADEAE_02000 2e-121 macB V ABC transporter, ATP-binding protein
LEHADEAE_02001 3e-210 yknZ V ABC transporter (permease)
LEHADEAE_02002 1.1e-130 fruR K Transcriptional regulator
LEHADEAE_02003 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
LEHADEAE_02004 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LEHADEAE_02005 3.3e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LEHADEAE_02006 1.7e-36 ykoA
LEHADEAE_02007 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LEHADEAE_02008 1.7e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEHADEAE_02009 3.6e-235 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LEHADEAE_02010 5.5e-12 S Uncharacterized protein YkpC
LEHADEAE_02011 6.9e-184 mreB D Rod-share determining protein MreBH
LEHADEAE_02012 1.8e-44 abrB K of stationary sporulation gene expression
LEHADEAE_02013 3.4e-244 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
LEHADEAE_02014 1e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
LEHADEAE_02015 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
LEHADEAE_02016 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LEHADEAE_02017 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEHADEAE_02018 8.2e-31 ykzG S Belongs to the UPF0356 family
LEHADEAE_02019 7.4e-146 ykrA S hydrolases of the HAD superfamily
LEHADEAE_02020 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEHADEAE_02022 1.6e-101 recN L Putative cell-wall binding lipoprotein
LEHADEAE_02023 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LEHADEAE_02024 0.0 Q Polyketide synthase of type I
LEHADEAE_02025 0.0 Q polyketide synthase
LEHADEAE_02026 0.0 Q Polyketide synthase of type I
LEHADEAE_02027 0.0 Q Polyketide synthase of type I
LEHADEAE_02028 0.0 Q Polyketide synthase of type I
LEHADEAE_02029 0.0 Q Polyketide synthase of type I
LEHADEAE_02030 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
LEHADEAE_02031 7.4e-208 V Beta-lactamase
LEHADEAE_02032 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEHADEAE_02033 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEHADEAE_02034 1.1e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEHADEAE_02035 1.2e-250 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEHADEAE_02036 8.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
LEHADEAE_02037 4.6e-135 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
LEHADEAE_02038 3.2e-275 speA 4.1.1.19 E Arginine
LEHADEAE_02039 3.5e-42 yktA S Belongs to the UPF0223 family
LEHADEAE_02040 5.4e-118 yktB S Belongs to the UPF0637 family
LEHADEAE_02041 6.3e-24 ykzI
LEHADEAE_02042 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
LEHADEAE_02043 4e-83 ykzC S Acetyltransferase (GNAT) family
LEHADEAE_02044 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
LEHADEAE_02045 8.3e-186 ylaA
LEHADEAE_02046 1.9e-43 ylaB
LEHADEAE_02047 1.2e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
LEHADEAE_02048 1.3e-13 sigC S Putative zinc-finger
LEHADEAE_02049 1.3e-36 ylaE
LEHADEAE_02050 6.7e-24 S Family of unknown function (DUF5325)
LEHADEAE_02051 0.0 typA T GTP-binding protein TypA
LEHADEAE_02052 6.6e-48 ylaH S YlaH-like protein
LEHADEAE_02053 1.4e-33 ylaI S protein conserved in bacteria
LEHADEAE_02054 9.7e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEHADEAE_02055 1.3e-243 phoH T ATPase related to phosphate starvation-inducible protein PhoH
LEHADEAE_02056 8.5e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LEHADEAE_02057 1.3e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
LEHADEAE_02058 8.7e-44 ylaN S Belongs to the UPF0358 family
LEHADEAE_02059 1.9e-212 ftsW D Belongs to the SEDS family
LEHADEAE_02060 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LEHADEAE_02061 5.9e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LEHADEAE_02062 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LEHADEAE_02063 1.2e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LEHADEAE_02064 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LEHADEAE_02065 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LEHADEAE_02066 1.9e-50 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LEHADEAE_02067 2e-163 ctaG S cytochrome c oxidase
LEHADEAE_02068 3.2e-59 ylbA S YugN-like family
LEHADEAE_02069 2.2e-73 ylbB T COG0517 FOG CBS domain
LEHADEAE_02070 2.3e-198 ylbC S protein with SCP PR1 domains
LEHADEAE_02071 2.1e-54 ylbD S Putative coat protein
LEHADEAE_02072 8.8e-37 ylbE S YlbE-like protein
LEHADEAE_02073 1.2e-71 ylbF S Belongs to the UPF0342 family
LEHADEAE_02074 9.4e-43 ylbG S UPF0298 protein
LEHADEAE_02076 6e-97 rsmD 2.1.1.171 L Methyltransferase
LEHADEAE_02077 9.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LEHADEAE_02078 6.3e-216 ylbJ S Sporulation integral membrane protein YlbJ
LEHADEAE_02079 4.4e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
LEHADEAE_02080 1.6e-188 ylbL T Belongs to the peptidase S16 family
LEHADEAE_02081 2.5e-228 ylbM S Belongs to the UPF0348 family
LEHADEAE_02082 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
LEHADEAE_02083 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LEHADEAE_02084 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LEHADEAE_02085 1.2e-88 ylbP K n-acetyltransferase
LEHADEAE_02086 7.2e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LEHADEAE_02087 6.3e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LEHADEAE_02088 1.2e-77 mraZ K Belongs to the MraZ family
LEHADEAE_02089 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LEHADEAE_02090 2.9e-52 ftsL D Essential cell division protein
LEHADEAE_02091 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LEHADEAE_02092 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
LEHADEAE_02093 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LEHADEAE_02094 2.2e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LEHADEAE_02095 6.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LEHADEAE_02096 2.2e-185 spoVE D Belongs to the SEDS family
LEHADEAE_02097 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LEHADEAE_02098 6.9e-167 murB 1.3.1.98 M cell wall formation
LEHADEAE_02099 4.8e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LEHADEAE_02100 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LEHADEAE_02101 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LEHADEAE_02102 0.0 bpr O COG1404 Subtilisin-like serine proteases
LEHADEAE_02103 1.9e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LEHADEAE_02104 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEHADEAE_02105 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEHADEAE_02106 1.6e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LEHADEAE_02107 1.1e-250 argE 3.5.1.16 E Acetylornithine deacetylase
LEHADEAE_02108 2.2e-38 ylmC S sporulation protein
LEHADEAE_02109 1.5e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
LEHADEAE_02110 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LEHADEAE_02111 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LEHADEAE_02112 5.2e-41 yggT S membrane
LEHADEAE_02113 1.6e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
LEHADEAE_02114 8.9e-68 divIVA D Cell division initiation protein
LEHADEAE_02115 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LEHADEAE_02116 1.2e-61 dksA T COG1734 DnaK suppressor protein
LEHADEAE_02117 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LEHADEAE_02118 5.1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LEHADEAE_02119 1.4e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LEHADEAE_02120 8.8e-232 pyrP F Xanthine uracil
LEHADEAE_02121 5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LEHADEAE_02122 3.6e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LEHADEAE_02123 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LEHADEAE_02124 0.0 carB 6.3.5.5 F Belongs to the CarB family
LEHADEAE_02125 5.9e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LEHADEAE_02126 1.1e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LEHADEAE_02127 6.1e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LEHADEAE_02128 2.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LEHADEAE_02130 1.1e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LEHADEAE_02131 1.1e-176 cysP P phosphate transporter
LEHADEAE_02132 2.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LEHADEAE_02133 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
LEHADEAE_02134 4.5e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LEHADEAE_02135 3.2e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
LEHADEAE_02136 2.7e-77 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
LEHADEAE_02137 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LEHADEAE_02138 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
LEHADEAE_02139 8.5e-154 yloC S stress-induced protein
LEHADEAE_02140 1.5e-40 ylzA S Belongs to the UPF0296 family
LEHADEAE_02141 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LEHADEAE_02142 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LEHADEAE_02143 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LEHADEAE_02144 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LEHADEAE_02145 1.5e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LEHADEAE_02146 1.2e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LEHADEAE_02147 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LEHADEAE_02148 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LEHADEAE_02149 2.3e-139 stp 3.1.3.16 T phosphatase
LEHADEAE_02150 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LEHADEAE_02151 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LEHADEAE_02152 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LEHADEAE_02153 5.8e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
LEHADEAE_02154 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LEHADEAE_02155 5.5e-59 asp S protein conserved in bacteria
LEHADEAE_02156 2.4e-303 yloV S kinase related to dihydroxyacetone kinase
LEHADEAE_02157 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
LEHADEAE_02158 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
LEHADEAE_02159 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LEHADEAE_02160 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LEHADEAE_02161 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LEHADEAE_02162 5.9e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LEHADEAE_02163 4.6e-129 IQ reductase
LEHADEAE_02164 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LEHADEAE_02165 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LEHADEAE_02166 0.0 smc D Required for chromosome condensation and partitioning
LEHADEAE_02167 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LEHADEAE_02168 7.9e-140 S Phosphotransferase enzyme family
LEHADEAE_02169 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LEHADEAE_02170 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LEHADEAE_02171 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LEHADEAE_02172 1.7e-35 ylqC S Belongs to the UPF0109 family
LEHADEAE_02173 1.3e-61 ylqD S YlqD protein
LEHADEAE_02174 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LEHADEAE_02175 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LEHADEAE_02176 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LEHADEAE_02177 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LEHADEAE_02178 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEHADEAE_02179 1.7e-304 ylqG
LEHADEAE_02180 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
LEHADEAE_02181 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LEHADEAE_02182 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LEHADEAE_02183 1.6e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
LEHADEAE_02184 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEHADEAE_02185 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LEHADEAE_02186 1.6e-171 xerC L tyrosine recombinase XerC
LEHADEAE_02187 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LEHADEAE_02188 4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LEHADEAE_02189 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LEHADEAE_02190 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LEHADEAE_02191 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
LEHADEAE_02192 2.5e-31 fliE N Flagellar hook-basal body
LEHADEAE_02193 1.4e-263 fliF N The M ring may be actively involved in energy transduction
LEHADEAE_02194 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LEHADEAE_02195 1.5e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
LEHADEAE_02196 5.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LEHADEAE_02197 2e-71 fliJ N Flagellar biosynthesis chaperone
LEHADEAE_02198 1.3e-47 ylxF S MgtE intracellular N domain
LEHADEAE_02199 8e-204 fliK N Flagellar hook-length control protein
LEHADEAE_02200 2.4e-72 flgD N Flagellar basal body rod modification protein
LEHADEAE_02201 5.7e-138 flgG N Flagellar basal body rod
LEHADEAE_02202 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
LEHADEAE_02203 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LEHADEAE_02204 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LEHADEAE_02205 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
LEHADEAE_02206 1.9e-110 fliZ N Flagellar biosynthesis protein, FliO
LEHADEAE_02207 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
LEHADEAE_02208 2e-37 fliQ N Role in flagellar biosynthesis
LEHADEAE_02209 1.2e-130 fliR N Flagellar biosynthetic protein FliR
LEHADEAE_02210 9e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEHADEAE_02211 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LEHADEAE_02212 6.3e-191 flhF N Flagellar biosynthesis regulator FlhF
LEHADEAE_02213 7e-156 flhG D Belongs to the ParA family
LEHADEAE_02214 1.2e-191 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LEHADEAE_02215 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
LEHADEAE_02216 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
LEHADEAE_02217 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LEHADEAE_02218 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LEHADEAE_02219 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEHADEAE_02220 8e-50 ylxL
LEHADEAE_02221 1.9e-130 rpsB J Belongs to the universal ribosomal protein uS2 family
LEHADEAE_02222 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LEHADEAE_02223 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LEHADEAE_02224 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LEHADEAE_02225 6.4e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LEHADEAE_02226 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
LEHADEAE_02227 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LEHADEAE_02228 5.9e-233 rasP M zinc metalloprotease
LEHADEAE_02229 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LEHADEAE_02230 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LEHADEAE_02231 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
LEHADEAE_02232 5.4e-206 nusA K Participates in both transcription termination and antitermination
LEHADEAE_02233 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
LEHADEAE_02234 1.8e-47 ylxQ J ribosomal protein
LEHADEAE_02235 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LEHADEAE_02236 3.9e-44 ylxP S protein conserved in bacteria
LEHADEAE_02237 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LEHADEAE_02238 4.7e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LEHADEAE_02239 6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LEHADEAE_02240 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LEHADEAE_02241 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LEHADEAE_02242 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
LEHADEAE_02243 1.2e-233 pepR S Belongs to the peptidase M16 family
LEHADEAE_02244 2.6e-42 ymxH S YlmC YmxH family
LEHADEAE_02245 1e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
LEHADEAE_02246 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LEHADEAE_02247 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LEHADEAE_02248 2.1e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LEHADEAE_02249 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LEHADEAE_02250 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LEHADEAE_02251 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
LEHADEAE_02252 6.3e-31 S YlzJ-like protein
LEHADEAE_02253 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LEHADEAE_02254 4.4e-132 ymfC K Transcriptional regulator
LEHADEAE_02255 3e-227 ymfD EGP Major facilitator Superfamily
LEHADEAE_02256 2.1e-76 K helix_turn_helix multiple antibiotic resistance protein
LEHADEAE_02257 0.0 ydgH S drug exporters of the RND superfamily
LEHADEAE_02258 1.3e-235 ymfF S Peptidase M16
LEHADEAE_02259 6e-241 ymfH S zinc protease
LEHADEAE_02260 6.6e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LEHADEAE_02261 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
LEHADEAE_02262 1e-142 ymfK S Protein of unknown function (DUF3388)
LEHADEAE_02263 2.5e-124 ymfM S protein conserved in bacteria
LEHADEAE_02264 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEHADEAE_02265 1.2e-230 cinA 3.5.1.42 S Belongs to the CinA family
LEHADEAE_02266 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LEHADEAE_02267 1.1e-193 pbpX V Beta-lactamase
LEHADEAE_02268 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
LEHADEAE_02269 4.9e-153 ymdB S protein conserved in bacteria
LEHADEAE_02270 1.2e-36 spoVS S Stage V sporulation protein S
LEHADEAE_02271 5.3e-195 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LEHADEAE_02272 3.7e-213 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LEHADEAE_02273 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LEHADEAE_02274 4.6e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LEHADEAE_02275 1.7e-88 cotE S Spore coat protein
LEHADEAE_02276 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LEHADEAE_02277 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LEHADEAE_02279 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
LEHADEAE_02280 5.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LEHADEAE_02281 1.1e-183 pksD Q Acyl transferase domain
LEHADEAE_02282 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LEHADEAE_02283 5.5e-34 acpK IQ Phosphopantetheine attachment site
LEHADEAE_02284 2.6e-241 pksG 2.3.3.10 I synthase
LEHADEAE_02285 3.5e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
LEHADEAE_02286 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
LEHADEAE_02287 0.0 rhiB IQ polyketide synthase
LEHADEAE_02288 0.0 Q Polyketide synthase of type I
LEHADEAE_02289 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
LEHADEAE_02290 0.0 dhbF IQ polyketide synthase
LEHADEAE_02291 0.0 pks13 HQ Beta-ketoacyl synthase
LEHADEAE_02292 4.2e-228 cypA C Cytochrome P450
LEHADEAE_02293 1.9e-77 nucB M Deoxyribonuclease NucA/NucB
LEHADEAE_02294 3.6e-118 yoaK S Membrane
LEHADEAE_02295 4.1e-62 ymzB
LEHADEAE_02296 5.7e-255 aprX O Belongs to the peptidase S8 family
LEHADEAE_02297 3e-125 ymaC S Replication protein
LEHADEAE_02298 6e-79 ymaD O redox protein, regulator of disulfide bond formation
LEHADEAE_02299 2.6e-53 ebrB P Small Multidrug Resistance protein
LEHADEAE_02300 2.6e-47 ebrA P Small Multidrug Resistance protein
LEHADEAE_02302 3.3e-44 ymaF S YmaF family
LEHADEAE_02303 4.3e-172 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LEHADEAE_02304 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LEHADEAE_02305 1.8e-41
LEHADEAE_02306 1.8e-20 ymzA
LEHADEAE_02307 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LEHADEAE_02308 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEHADEAE_02309 1.4e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LEHADEAE_02310 3.4e-109 ymaB S MutT family
LEHADEAE_02311 2.4e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEHADEAE_02312 1.3e-176 spoVK O stage V sporulation protein K
LEHADEAE_02313 1.9e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LEHADEAE_02314 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LEHADEAE_02315 4.3e-68 glnR K transcriptional
LEHADEAE_02316 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
LEHADEAE_02317 7e-94
LEHADEAE_02319 3.2e-11
LEHADEAE_02321 1.2e-40 S Protein of unknown function (DUF2568)
LEHADEAE_02322 7.4e-25 T Histidine kinase
LEHADEAE_02323 4.3e-208 mrjp G Major royal jelly protein
LEHADEAE_02324 4.9e-249 xynT G MFS/sugar transport protein
LEHADEAE_02325 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
LEHADEAE_02326 7.3e-206 xylR GK ROK family
LEHADEAE_02327 1.2e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
LEHADEAE_02328 1.6e-285 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
LEHADEAE_02329 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
LEHADEAE_02334 3.1e-184 adhP 1.1.1.1 C alcohol dehydrogenase
LEHADEAE_02335 1e-09
LEHADEAE_02337 1.4e-141 yoaP 3.1.3.18 K YoaP-like
LEHADEAE_02338 1.6e-99 J Acetyltransferase (GNAT) domain
LEHADEAE_02339 5.6e-115 ynaE S Domain of unknown function (DUF3885)
LEHADEAE_02340 3.3e-200 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEHADEAE_02341 3.4e-117 AA10,CBM73 S Pfam:Chitin_bind_3
LEHADEAE_02343 1.6e-91 yvgO
LEHADEAE_02345 0.0 yobO M Pectate lyase superfamily protein
LEHADEAE_02346 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LEHADEAE_02347 9.4e-139 yndL S Replication protein
LEHADEAE_02348 9.1e-08
LEHADEAE_02349 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
LEHADEAE_02350 1.2e-71 yndM S Protein of unknown function (DUF2512)
LEHADEAE_02351 2.1e-12 yoaW
LEHADEAE_02352 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LEHADEAE_02353 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LEHADEAE_02354 3.5e-112 yneB L resolvase
LEHADEAE_02355 9.8e-33 ynzC S UPF0291 protein
LEHADEAE_02356 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LEHADEAE_02357 1.4e-80 yneE S Sporulation inhibitor of replication protein sirA
LEHADEAE_02358 2.3e-28 yneF S UPF0154 protein
LEHADEAE_02359 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
LEHADEAE_02360 1.7e-125 ccdA O cytochrome c biogenesis protein
LEHADEAE_02361 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
LEHADEAE_02362 4.3e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
LEHADEAE_02363 5.5e-74 yneK S Protein of unknown function (DUF2621)
LEHADEAE_02364 1.4e-62 hspX O Spore coat protein
LEHADEAE_02365 2.3e-19 sspP S Belongs to the SspP family
LEHADEAE_02366 7.5e-15 sspO S Belongs to the SspO family
LEHADEAE_02367 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LEHADEAE_02368 3.7e-93 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LEHADEAE_02371 7.1e-18 tlp S Belongs to the Tlp family
LEHADEAE_02372 8.3e-75 yneP S Thioesterase-like superfamily
LEHADEAE_02373 1.4e-52 yneQ
LEHADEAE_02374 1.1e-49 yneR S Belongs to the HesB IscA family
LEHADEAE_02375 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LEHADEAE_02376 1.5e-68 yccU S CoA-binding protein
LEHADEAE_02377 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEHADEAE_02378 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LEHADEAE_02379 6e-13
LEHADEAE_02380 5.1e-41 ynfC
LEHADEAE_02381 5.2e-246 agcS E Sodium alanine symporter
LEHADEAE_02382 5.7e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
LEHADEAE_02383 1.3e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
LEHADEAE_02384 6.8e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
LEHADEAE_02385 6e-210 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LEHADEAE_02386 1.4e-94 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEHADEAE_02387 1.2e-38 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LEHADEAE_02388 1.5e-178 kdgR_1 K transcriptional
LEHADEAE_02389 4e-221 exuT G Sugar (and other) transporter
LEHADEAE_02390 5.4e-155 yndG S DoxX-like family
LEHADEAE_02391 9.5e-80 yndH S Domain of unknown function (DUF4166)
LEHADEAE_02392 1.2e-294 yndJ S YndJ-like protein
LEHADEAE_02393 2e-33 S Platelet-activating factor acetylhydrolase, isoform II
LEHADEAE_02394 5.7e-25 S Platelet-activating factor acetylhydrolase, isoform II
LEHADEAE_02395 6e-285 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
LEHADEAE_02396 1.2e-49 S Domain of unknown function (DUF4870)
LEHADEAE_02397 2.3e-230 T PhoQ Sensor
LEHADEAE_02398 2.3e-125 T Transcriptional regulatory protein, C terminal
LEHADEAE_02399 7e-250 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
LEHADEAE_02400 4.7e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
LEHADEAE_02401 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02402 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02403 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02404 9.6e-217 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LEHADEAE_02405 6.4e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LEHADEAE_02406 5.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LEHADEAE_02407 9.9e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LEHADEAE_02408 4.2e-251 yxjC EG COG2610 H gluconate symporter and related permeases
LEHADEAE_02409 5.6e-217 bioI 1.14.14.46 C Cytochrome P450
LEHADEAE_02410 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LEHADEAE_02411 2e-126 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LEHADEAE_02412 3.1e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LEHADEAE_02413 1.1e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LEHADEAE_02414 8.2e-145 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LEHADEAE_02415 9.6e-68 yngA S membrane
LEHADEAE_02416 8.9e-159 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LEHADEAE_02417 3.2e-104 yngC S SNARE associated Golgi protein
LEHADEAE_02418 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LEHADEAE_02419 1.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LEHADEAE_02420 3.6e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
LEHADEAE_02421 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
LEHADEAE_02422 6.7e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
LEHADEAE_02423 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEHADEAE_02424 1.8e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
LEHADEAE_02425 7.3e-302 yngK T Glycosyl hydrolase-like 10
LEHADEAE_02426 1.2e-64 yngL S Protein of unknown function (DUF1360)
LEHADEAE_02427 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
LEHADEAE_02428 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02429 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02430 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02431 5.5e-239 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02432 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
LEHADEAE_02433 3.4e-140 srfAD Q thioesterase
LEHADEAE_02434 6.7e-248 bamJ E Aminotransferase class I and II
LEHADEAE_02435 3.2e-129 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
LEHADEAE_02436 1.7e-108 yczE S membrane
LEHADEAE_02437 4.5e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEHADEAE_02438 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
LEHADEAE_02439 5.5e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LEHADEAE_02440 3.9e-159 bsdA K LysR substrate binding domain
LEHADEAE_02441 1.2e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LEHADEAE_02442 3.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LEHADEAE_02443 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
LEHADEAE_02445 7.1e-62 yclD
LEHADEAE_02446 1.2e-269 dtpT E amino acid peptide transporter
LEHADEAE_02447 9.2e-277 yclG M Pectate lyase superfamily protein
LEHADEAE_02449 7.8e-294 gerKA EG Spore germination protein
LEHADEAE_02450 5.2e-234 gerKC S spore germination
LEHADEAE_02451 1.1e-195 gerKB F Spore germination protein
LEHADEAE_02452 1.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEHADEAE_02453 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEHADEAE_02454 2.1e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
LEHADEAE_02455 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
LEHADEAE_02456 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
LEHADEAE_02457 6.4e-218 yxeP 3.5.1.47 E hydrolase activity
LEHADEAE_02458 1.9e-250 yxeQ S MmgE/PrpD family
LEHADEAE_02459 1.6e-120 yclH P ABC transporter
LEHADEAE_02460 1e-225 yclI V ABC transporter (permease) YclI
LEHADEAE_02461 6.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEHADEAE_02462 6.4e-260 T PhoQ Sensor
LEHADEAE_02463 9.5e-81 S aspartate phosphatase
LEHADEAE_02465 4.5e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
LEHADEAE_02466 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEHADEAE_02467 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEHADEAE_02468 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
LEHADEAE_02469 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
LEHADEAE_02470 2.1e-247 ycnB EGP Major facilitator Superfamily
LEHADEAE_02471 3e-151 ycnC K Transcriptional regulator
LEHADEAE_02472 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
LEHADEAE_02473 1e-44 ycnE S Monooxygenase
LEHADEAE_02474 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
LEHADEAE_02475 7e-259 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LEHADEAE_02476 4.2e-218 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEHADEAE_02477 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LEHADEAE_02478 3.6e-149 glcU U Glucose uptake
LEHADEAE_02479 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEHADEAE_02480 2.3e-97 ycnI S protein conserved in bacteria
LEHADEAE_02481 3.3e-297 ycnJ P protein, homolog of Cu resistance protein CopC
LEHADEAE_02482 9.5e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
LEHADEAE_02483 1.6e-55
LEHADEAE_02484 1.8e-225 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
LEHADEAE_02485 5.2e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LEHADEAE_02486 1.1e-206 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
LEHADEAE_02487 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
LEHADEAE_02489 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LEHADEAE_02490 2.5e-138 ycsF S Belongs to the UPF0271 (lamB) family
LEHADEAE_02491 7.4e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
LEHADEAE_02492 4.3e-149 ycsI S Belongs to the D-glutamate cyclase family
LEHADEAE_02493 2.1e-137 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
LEHADEAE_02494 3.5e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
LEHADEAE_02495 1.3e-129 kipR K Transcriptional regulator
LEHADEAE_02496 2.5e-115 ycsK E anatomical structure formation involved in morphogenesis
LEHADEAE_02498 5.1e-56 yczJ S biosynthesis
LEHADEAE_02499 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
LEHADEAE_02500 5.1e-75 ydhF S Oxidoreductase
LEHADEAE_02501 4.5e-88 ydhF S Oxidoreductase
LEHADEAE_02502 0.0 mtlR K transcriptional regulator, MtlR
LEHADEAE_02503 5.5e-286 ydaB IQ acyl-CoA ligase
LEHADEAE_02504 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEHADEAE_02505 3.9e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
LEHADEAE_02506 2.1e-114 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LEHADEAE_02507 6.8e-77 ydaG 1.4.3.5 S general stress protein
LEHADEAE_02508 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LEHADEAE_02509 1.3e-47 ydzA EGP Major facilitator Superfamily
LEHADEAE_02510 4.3e-74 lrpC K Transcriptional regulator
LEHADEAE_02511 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LEHADEAE_02512 8.7e-201 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
LEHADEAE_02513 9.6e-147 ydaK T Diguanylate cyclase, GGDEF domain
LEHADEAE_02514 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
LEHADEAE_02515 7.2e-231 ydaM M Glycosyl transferase family group 2
LEHADEAE_02516 0.0 ydaN S Bacterial cellulose synthase subunit
LEHADEAE_02517 0.0 ydaO E amino acid
LEHADEAE_02518 1.1e-72 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LEHADEAE_02519 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LEHADEAE_02520 5.3e-64 K acetyltransferase
LEHADEAE_02522 1.4e-56 S Domain of unknown function (DUF4145)
LEHADEAE_02523 2.6e-24
LEHADEAE_02524 4.5e-22
LEHADEAE_02525 4e-23 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEHADEAE_02526 7.7e-85 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LEHADEAE_02527 6.3e-69
LEHADEAE_02528 3.4e-208 S Histidine kinase
LEHADEAE_02530 6.5e-13
LEHADEAE_02532 9.3e-74
LEHADEAE_02533 2.9e-97
LEHADEAE_02534 1.8e-38
LEHADEAE_02535 9.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
LEHADEAE_02537 6.5e-34 ydaT
LEHADEAE_02538 1.2e-70 yvaD S Family of unknown function (DUF5360)
LEHADEAE_02539 7.8e-53 yvaE P Small Multidrug Resistance protein
LEHADEAE_02540 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
LEHADEAE_02542 3.4e-58 ydbB G Cupin domain
LEHADEAE_02543 8.5e-60 ydbC S Domain of unknown function (DUF4937
LEHADEAE_02544 1.2e-154 ydbD P Catalase
LEHADEAE_02545 6.5e-201 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LEHADEAE_02546 1e-298 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LEHADEAE_02547 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
LEHADEAE_02548 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEHADEAE_02549 4e-158 ydbI S AI-2E family transporter
LEHADEAE_02550 2.3e-170 ydbJ V ABC transporter, ATP-binding protein
LEHADEAE_02551 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LEHADEAE_02552 4.6e-52 ydbL
LEHADEAE_02553 3e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
LEHADEAE_02554 1.5e-10 S Fur-regulated basic protein B
LEHADEAE_02555 5.8e-09 S Fur-regulated basic protein A
LEHADEAE_02556 4e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEHADEAE_02557 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LEHADEAE_02558 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LEHADEAE_02559 2.3e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LEHADEAE_02560 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LEHADEAE_02561 1.3e-60 ydbS S Bacterial PH domain
LEHADEAE_02562 2.9e-260 ydbT S Membrane
LEHADEAE_02563 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
LEHADEAE_02564 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LEHADEAE_02565 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
LEHADEAE_02566 2.6e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEHADEAE_02567 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LEHADEAE_02568 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
LEHADEAE_02569 2.3e-145 rsbR T Positive regulator of sigma-B
LEHADEAE_02570 1.8e-57 rsbS T antagonist
LEHADEAE_02571 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LEHADEAE_02572 1.7e-187 rsbU 3.1.3.3 KT phosphatase
LEHADEAE_02573 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
LEHADEAE_02574 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LEHADEAE_02575 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEHADEAE_02576 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
LEHADEAE_02577 0.0 yhgF K COG2183 Transcriptional accessory protein
LEHADEAE_02578 1.7e-14
LEHADEAE_02579 8.6e-59 ydcK S Belongs to the SprT family
LEHADEAE_02580 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02581 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02582 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02583 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_02584 4.6e-74 yobL S Bacterial EndoU nuclease
LEHADEAE_02585 6.8e-27 S SMI1 / KNR4 family
LEHADEAE_02586 5.5e-15 S Membrane
LEHADEAE_02587 6.7e-70 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEHADEAE_02588 1.2e-31 xhlB S SPP1 phage holin
LEHADEAE_02589 5e-28 bhlA S BhlA holin family
LEHADEAE_02592 1.5e-143 S Domain of unknown function (DUF2479)
LEHADEAE_02593 0.0 M Pectate lyase superfamily protein
LEHADEAE_02594 6.3e-230 NU Prophage endopeptidase tail
LEHADEAE_02595 4.1e-105 S Phage tail protein
LEHADEAE_02596 0.0 D phage tail tape measure protein
LEHADEAE_02598 4e-78 S Phage tail tube protein
LEHADEAE_02600 2.6e-49 S Bacteriophage HK97-gp10, putative tail-component
LEHADEAE_02601 5.6e-39 S Phage head-tail joining protein
LEHADEAE_02602 1.1e-39 S Phage gp6-like head-tail connector protein
LEHADEAE_02603 2.7e-22
LEHADEAE_02604 3.9e-155 gp36 S capsid protein
LEHADEAE_02605 1.4e-81 S peptidase activity
LEHADEAE_02606 1.4e-168 S Phage portal protein
LEHADEAE_02607 3.2e-298 S Terminase
LEHADEAE_02608 2.3e-79 L phage terminase small subunit
LEHADEAE_02609 2.7e-14
LEHADEAE_02610 2.4e-91 S AAA ATPase domain
LEHADEAE_02612 1e-72 L Phage integrase family
LEHADEAE_02613 5.2e-52 wecC 1.1.1.336 M ArpU family transcriptional regulator
LEHADEAE_02616 2.7e-22
LEHADEAE_02619 7.6e-111 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
LEHADEAE_02623 3.6e-15 yqaO S Phage-like element PBSX protein XtrA
LEHADEAE_02627 1.2e-28
LEHADEAE_02630 6.3e-42 dnaC L IstB-like ATP binding protein
LEHADEAE_02631 2.7e-83 ybl78 L Conserved phage C-terminus (Phg_2220_C)
LEHADEAE_02633 3.7e-38 S Domain of unknown function (DUF771)
LEHADEAE_02635 7.8e-22 K Helix-turn-helix XRE-family like proteins
LEHADEAE_02638 2.1e-69
LEHADEAE_02639 3e-116 L Phage integrase family
LEHADEAE_02641 3.5e-97 L Integrase
LEHADEAE_02642 1.8e-34 yoeD G Helix-turn-helix domain
LEHADEAE_02643 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LEHADEAE_02644 5.2e-199 ybcL EGP Major facilitator Superfamily
LEHADEAE_02645 1.8e-50 ybzH K Helix-turn-helix domain
LEHADEAE_02646 1.5e-14 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEHADEAE_02647 1.1e-153 gltR1 K Transcriptional regulator
LEHADEAE_02648 2.1e-182 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LEHADEAE_02649 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LEHADEAE_02650 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
LEHADEAE_02651 2.9e-149 gltC K Transcriptional regulator
LEHADEAE_02652 6.2e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LEHADEAE_02653 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEHADEAE_02654 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LEHADEAE_02655 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LEHADEAE_02656 8.3e-40 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEHADEAE_02657 3.2e-133 yoxB
LEHADEAE_02658 7.4e-204 yoaB EGP Major facilitator Superfamily
LEHADEAE_02659 1.7e-268 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
LEHADEAE_02660 2.8e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEHADEAE_02661 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LEHADEAE_02664 6.9e-96 hpr K helix_turn_helix multiple antibiotic resistance protein
LEHADEAE_02665 1.5e-43
LEHADEAE_02666 1.9e-130 IQ Enoyl-(Acyl carrier protein) reductase
LEHADEAE_02667 1.7e-60 ykvN K Transcriptional regulator
LEHADEAE_02668 3.2e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
LEHADEAE_02669 1.1e-130 yobQ K helix_turn_helix, arabinose operon control protein
LEHADEAE_02670 1.2e-92 yobS K Transcriptional regulator
LEHADEAE_02671 7.2e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
LEHADEAE_02672 1.2e-91 yobW
LEHADEAE_02673 8.4e-54 czrA K transcriptional
LEHADEAE_02674 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LEHADEAE_02675 3.6e-91 yozB S membrane
LEHADEAE_02676 8.9e-139 yocB J Protein required for attachment to host cells
LEHADEAE_02677 1.6e-93 yocC
LEHADEAE_02678 2.4e-186 yocD 3.4.17.13 V peptidase S66
LEHADEAE_02680 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
LEHADEAE_02681 0.0 recQ 3.6.4.12 L DNA helicase
LEHADEAE_02682 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LEHADEAE_02684 2.5e-54 dksA T general stress protein
LEHADEAE_02685 7.8e-10 yocL
LEHADEAE_02686 7.5e-09
LEHADEAE_02687 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
LEHADEAE_02688 3.8e-44 yozN
LEHADEAE_02689 8.5e-37 yocN
LEHADEAE_02690 2.4e-56 yozO S Bacterial PH domain
LEHADEAE_02692 3.6e-31 yozC
LEHADEAE_02693 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
LEHADEAE_02694 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
LEHADEAE_02695 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
LEHADEAE_02696 8.7e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LEHADEAE_02697 1.9e-159 yocS S -transporter
LEHADEAE_02698 1.1e-138 S Metallo-beta-lactamase superfamily
LEHADEAE_02699 2.1e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LEHADEAE_02700 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LEHADEAE_02701 0.0 yojO P Von Willebrand factor
LEHADEAE_02702 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
LEHADEAE_02703 2.1e-108 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LEHADEAE_02704 5.8e-225 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LEHADEAE_02705 6.9e-223 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
LEHADEAE_02706 1.7e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEHADEAE_02708 1.4e-235 norM V Multidrug efflux pump
LEHADEAE_02709 2.2e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEHADEAE_02710 5.6e-126 yojG S deacetylase
LEHADEAE_02711 3.7e-60 yojF S Protein of unknown function (DUF1806)
LEHADEAE_02712 4.9e-23
LEHADEAE_02713 1.1e-161 rarD S -transporter
LEHADEAE_02714 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
LEHADEAE_02716 7.7e-67 yodA S tautomerase
LEHADEAE_02717 6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
LEHADEAE_02718 3e-56 yodB K transcriptional
LEHADEAE_02719 4.5e-106 yodC C nitroreductase
LEHADEAE_02720 3.7e-108 mhqD S Carboxylesterase
LEHADEAE_02721 8.5e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
LEHADEAE_02722 1.4e-19 S Protein of unknown function (DUF3311)
LEHADEAE_02723 1.1e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEHADEAE_02724 1.8e-278 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
LEHADEAE_02725 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEHADEAE_02726 2.6e-132 yydK K Transcriptional regulator
LEHADEAE_02727 2.3e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
LEHADEAE_02728 8.3e-128 yodH Q Methyltransferase
LEHADEAE_02729 1.9e-21 yodI
LEHADEAE_02730 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LEHADEAE_02731 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
LEHADEAE_02733 3.3e-55 yodL S YodL-like
LEHADEAE_02734 2.3e-102 yodM 3.6.1.27 I Acid phosphatase homologues
LEHADEAE_02735 6.2e-24 yozD S YozD-like protein
LEHADEAE_02737 1.7e-125 yodN
LEHADEAE_02738 5.5e-27 E lactoylglutathione lyase activity
LEHADEAE_02739 9.1e-36 yozE S Belongs to the UPF0346 family
LEHADEAE_02740 9.2e-46 yokU S YokU-like protein, putative antitoxin
LEHADEAE_02741 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
LEHADEAE_02742 4.9e-154 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
LEHADEAE_02743 9e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
LEHADEAE_02744 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LEHADEAE_02745 6.5e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LEHADEAE_02746 4.6e-244 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEHADEAE_02747 2.1e-30 yosT L Bacterial transcription activator, effector binding domain
LEHADEAE_02749 1.4e-144 yiiD K acetyltransferase
LEHADEAE_02750 1.6e-241 cgeD M maturation of the outermost layer of the spore
LEHADEAE_02751 1.2e-40 cgeC
LEHADEAE_02752 1.6e-52 cgeA
LEHADEAE_02753 1.4e-178 cgeB S Spore maturation protein
LEHADEAE_02754 8.3e-218 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
LEHADEAE_02755 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
LEHADEAE_02761 6.5e-77
LEHADEAE_02762 4.7e-19 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
LEHADEAE_02763 2.6e-08
LEHADEAE_02766 1.1e-75 yoqH M LysM domain
LEHADEAE_02767 5e-207 S aspartate phosphatase
LEHADEAE_02770 7.2e-157 3.4.24.40 S amine dehydrogenase activity
LEHADEAE_02772 2e-08 S Domain of unknown function (DUF4879)
LEHADEAE_02773 7e-24
LEHADEAE_02774 4.3e-29 S Acetyltransferase (GNAT) domain
LEHADEAE_02775 3.8e-89 yokK S SMI1 / KNR4 family
LEHADEAE_02776 2.8e-52 S SMI1-KNR4 cell-wall
LEHADEAE_02777 2.9e-65 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LEHADEAE_02778 1.9e-202 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LEHADEAE_02779 1.9e-87 G SMI1-KNR4 cell-wall
LEHADEAE_02780 8.7e-75 yokF 3.1.31.1 L RNA catabolic process
LEHADEAE_02783 1.2e-302 yokA L Recombinase
LEHADEAE_02784 6.8e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
LEHADEAE_02785 4.7e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LEHADEAE_02786 2.7e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LEHADEAE_02787 1.4e-66 ypoP K transcriptional
LEHADEAE_02788 6.1e-97 ypmS S protein conserved in bacteria
LEHADEAE_02789 6.4e-134 ypmR E GDSL-like Lipase/Acylhydrolase
LEHADEAE_02790 7.9e-114 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LEHADEAE_02791 1.4e-37 ypmP S Protein of unknown function (DUF2535)
LEHADEAE_02792 6.3e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LEHADEAE_02793 8.3e-174 pspF K Transcriptional regulator
LEHADEAE_02794 1.6e-109 hlyIII S protein, Hemolysin III
LEHADEAE_02795 3.9e-113 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LEHADEAE_02796 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LEHADEAE_02797 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LEHADEAE_02798 8.5e-113 ypjP S YpjP-like protein
LEHADEAE_02799 1.1e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
LEHADEAE_02800 1e-75 yphP S Belongs to the UPF0403 family
LEHADEAE_02801 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LEHADEAE_02802 8.3e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
LEHADEAE_02803 3.1e-99 ypgQ S phosphohydrolase
LEHADEAE_02804 7.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LEHADEAE_02805 3.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LEHADEAE_02806 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LEHADEAE_02807 1e-30 cspD K Cold-shock protein
LEHADEAE_02808 1.3e-11 degR
LEHADEAE_02809 1.2e-36 S Protein of unknown function (DUF2564)
LEHADEAE_02810 1.5e-28 ypeQ S Zinc-finger
LEHADEAE_02811 9.1e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
LEHADEAE_02812 1.7e-117 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LEHADEAE_02813 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
LEHADEAE_02815 2.2e-162 polA 2.7.7.7 L 5'3' exonuclease
LEHADEAE_02817 2.2e-38 ypbS S Protein of unknown function (DUF2533)
LEHADEAE_02818 0.0 ypbR S Dynamin family
LEHADEAE_02819 1.1e-89 ypbQ S protein conserved in bacteria
LEHADEAE_02820 6.1e-202 bcsA Q Naringenin-chalcone synthase
LEHADEAE_02821 4.5e-106 J Acetyltransferase (GNAT) domain
LEHADEAE_02822 6e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
LEHADEAE_02824 3.9e-22 ydfR S Protein of unknown function (DUF421)
LEHADEAE_02825 1.2e-56 ydfR S Protein of unknown function (DUF421)
LEHADEAE_02826 9.4e-98 yrdC 3.5.1.19 Q Isochorismatase family
LEHADEAE_02828 8.5e-235 pbuX F xanthine
LEHADEAE_02829 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LEHADEAE_02830 4.3e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LEHADEAE_02831 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
LEHADEAE_02833 6.6e-22 S YpzG-like protein
LEHADEAE_02834 2.7e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LEHADEAE_02835 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LEHADEAE_02836 1.6e-97 ypsA S Belongs to the UPF0398 family
LEHADEAE_02837 9.9e-33 cotD S Inner spore coat protein D
LEHADEAE_02839 4.7e-219 yprB L RNase_H superfamily
LEHADEAE_02840 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LEHADEAE_02841 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
LEHADEAE_02842 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
LEHADEAE_02843 2.1e-49 yppG S YppG-like protein
LEHADEAE_02845 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
LEHADEAE_02848 2.6e-188 yppC S Protein of unknown function (DUF2515)
LEHADEAE_02849 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LEHADEAE_02850 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LEHADEAE_02851 2.5e-91 ypoC
LEHADEAE_02852 2.7e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LEHADEAE_02853 3e-130 dnaD L DNA replication protein DnaD
LEHADEAE_02854 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
LEHADEAE_02855 4.1e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LEHADEAE_02856 1.5e-80 ypmB S protein conserved in bacteria
LEHADEAE_02857 6.7e-23 ypmA S Protein of unknown function (DUF4264)
LEHADEAE_02858 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LEHADEAE_02859 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LEHADEAE_02860 2.1e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LEHADEAE_02861 1.7e-148 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LEHADEAE_02862 3.7e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LEHADEAE_02863 2.3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LEHADEAE_02864 8.2e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
LEHADEAE_02865 1.9e-132 bshB1 S proteins, LmbE homologs
LEHADEAE_02866 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
LEHADEAE_02867 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LEHADEAE_02868 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
LEHADEAE_02869 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
LEHADEAE_02870 2.9e-226 oxdC 4.1.1.2 G Oxalate decarboxylase
LEHADEAE_02871 9.5e-141 ypjB S sporulation protein
LEHADEAE_02872 2.9e-105 ypjA S membrane
LEHADEAE_02873 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
LEHADEAE_02874 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
LEHADEAE_02875 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
LEHADEAE_02876 3.2e-77 ypiF S Protein of unknown function (DUF2487)
LEHADEAE_02877 2.1e-99 ypiB S Belongs to the UPF0302 family
LEHADEAE_02878 3.5e-233 S COG0457 FOG TPR repeat
LEHADEAE_02879 8.1e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LEHADEAE_02880 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LEHADEAE_02881 1.9e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LEHADEAE_02882 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LEHADEAE_02883 2.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LEHADEAE_02884 2.8e-114 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
LEHADEAE_02885 1.2e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LEHADEAE_02886 1.8e-152 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LEHADEAE_02887 4.2e-289 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LEHADEAE_02888 9e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LEHADEAE_02889 3.2e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LEHADEAE_02890 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LEHADEAE_02891 1.1e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
LEHADEAE_02892 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LEHADEAE_02893 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEHADEAE_02894 4.7e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LEHADEAE_02895 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LEHADEAE_02896 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LEHADEAE_02897 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
LEHADEAE_02898 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LEHADEAE_02899 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LEHADEAE_02900 1.1e-133 yphF
LEHADEAE_02901 2.5e-16 yphE S Protein of unknown function (DUF2768)
LEHADEAE_02902 1.9e-189 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LEHADEAE_02903 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LEHADEAE_02904 1.6e-103 yphA
LEHADEAE_02905 4.7e-08 S YpzI-like protein
LEHADEAE_02906 1.7e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LEHADEAE_02907 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
LEHADEAE_02908 1e-111 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LEHADEAE_02909 4.2e-12 S Family of unknown function (DUF5359)
LEHADEAE_02910 2.2e-61 ypfA M Flagellar protein YcgR
LEHADEAE_02911 4.6e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
LEHADEAE_02912 1.5e-158 sleB 3.5.1.28 M Spore cortex-lytic enzyme
LEHADEAE_02913 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
LEHADEAE_02914 3.4e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
LEHADEAE_02915 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LEHADEAE_02916 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LEHADEAE_02917 9e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
LEHADEAE_02918 1.7e-84 ypbF S Protein of unknown function (DUF2663)
LEHADEAE_02919 1.7e-73 ypbE M Lysin motif
LEHADEAE_02920 5.2e-99 ypbD S metal-dependent membrane protease
LEHADEAE_02921 3e-270 recQ 3.6.4.12 L DNA helicase
LEHADEAE_02922 1.1e-192 ypbB 5.1.3.1 S protein conserved in bacteria
LEHADEAE_02923 3.6e-41 fer C Ferredoxin
LEHADEAE_02924 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LEHADEAE_02925 4.8e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LEHADEAE_02926 5.7e-192 rsiX
LEHADEAE_02927 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
LEHADEAE_02928 0.0 resE 2.7.13.3 T Histidine kinase
LEHADEAE_02929 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEHADEAE_02930 7.2e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LEHADEAE_02931 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
LEHADEAE_02932 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LEHADEAE_02933 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEHADEAE_02934 1.3e-88 spmB S Spore maturation protein
LEHADEAE_02935 2e-103 spmA S Spore maturation protein
LEHADEAE_02936 8.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
LEHADEAE_02937 3.8e-93 ypuI S Protein of unknown function (DUF3907)
LEHADEAE_02938 5.1e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LEHADEAE_02939 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LEHADEAE_02941 2.9e-93 ypuF S Domain of unknown function (DUF309)
LEHADEAE_02942 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LEHADEAE_02943 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LEHADEAE_02944 3.2e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LEHADEAE_02945 1.1e-110 ribE 2.5.1.9 H Riboflavin synthase
LEHADEAE_02946 3.1e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LEHADEAE_02947 6.4e-49 ypuD
LEHADEAE_02948 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LEHADEAE_02949 1.2e-80 ccdC1 O Protein of unknown function (DUF1453)
LEHADEAE_02950 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LEHADEAE_02951 1.9e-153 ypuA S Secreted protein
LEHADEAE_02952 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LEHADEAE_02953 3.2e-270 spoVAF EG Stage V sporulation protein AF
LEHADEAE_02954 5.2e-110 spoVAEA S stage V sporulation protein
LEHADEAE_02955 5e-57 spoVAEB S stage V sporulation protein
LEHADEAE_02956 1.2e-188 spoVAD I Stage V sporulation protein AD
LEHADEAE_02957 6e-79 spoVAC S stage V sporulation protein AC
LEHADEAE_02958 5.1e-60 spoVAB S Stage V sporulation protein AB
LEHADEAE_02959 1.8e-110 spoVAA S Stage V sporulation protein AA
LEHADEAE_02960 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEHADEAE_02961 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LEHADEAE_02962 1.9e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
LEHADEAE_02963 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
LEHADEAE_02964 2.4e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LEHADEAE_02965 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LEHADEAE_02966 2.8e-165 xerD L recombinase XerD
LEHADEAE_02967 3.7e-37 S Protein of unknown function (DUF4227)
LEHADEAE_02968 1.9e-80 fur P Belongs to the Fur family
LEHADEAE_02969 7.2e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LEHADEAE_02971 3.9e-34 yqkK
LEHADEAE_02972 5.7e-22
LEHADEAE_02973 3.8e-243 mleA 1.1.1.38 C malic enzyme
LEHADEAE_02974 1.6e-239 mleN C Na H antiporter
LEHADEAE_02975 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
LEHADEAE_02976 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
LEHADEAE_02977 1e-57 ansR K Transcriptional regulator
LEHADEAE_02978 4e-220 yqxK 3.6.4.12 L DNA helicase
LEHADEAE_02979 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
LEHADEAE_02981 2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
LEHADEAE_02983 9e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
LEHADEAE_02984 3.2e-39 yqkC S Protein of unknown function (DUF2552)
LEHADEAE_02985 7.7e-61 yqkB S Belongs to the HesB IscA family
LEHADEAE_02986 1.2e-172 yqkA K GrpB protein
LEHADEAE_02987 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
LEHADEAE_02988 8.7e-89 yqjY K acetyltransferase
LEHADEAE_02989 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEHADEAE_02990 2.1e-55 S YolD-like protein
LEHADEAE_02992 1.3e-185 yueF S transporter activity
LEHADEAE_02994 2.5e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LEHADEAE_02995 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
LEHADEAE_02996 9.6e-250 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
LEHADEAE_02997 5.5e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
LEHADEAE_02998 6.8e-173 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
LEHADEAE_02999 2e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEHADEAE_03000 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
LEHADEAE_03001 1.7e-238 pksG 2.3.3.10 I synthase
LEHADEAE_03002 2.6e-219 eryK 1.14.13.154 C Cytochrome P450
LEHADEAE_03003 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LEHADEAE_03004 0.0 Q Polyketide synthase of type I
LEHADEAE_03005 0.0 pfaA Q Polyketide synthase of type I
LEHADEAE_03006 0.0 pksJ Q Polyketide synthase of type I
LEHADEAE_03007 0.0 pksJ Q Polyketide synthase of type I
LEHADEAE_03008 0.0 Q Polyketide synthase of type I
LEHADEAE_03009 0.0 1.1.1.320 Q Polyketide synthase of type I
LEHADEAE_03010 0.0 pksJ Q Polyketide synthase of type I
LEHADEAE_03012 2e-08
LEHADEAE_03013 3.4e-39 S COG NOG14552 non supervised orthologous group
LEHADEAE_03014 1.3e-76 ctsR K Belongs to the CtsR family
LEHADEAE_03015 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
LEHADEAE_03016 7.2e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LEHADEAE_03017 0.0 clpC O Belongs to the ClpA ClpB family
LEHADEAE_03018 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LEHADEAE_03019 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LEHADEAE_03020 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
LEHADEAE_03021 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LEHADEAE_03022 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LEHADEAE_03023 1.2e-277 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LEHADEAE_03024 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
LEHADEAE_03025 5.3e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEHADEAE_03026 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LEHADEAE_03027 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEHADEAE_03028 4.2e-89 yacP S RNA-binding protein containing a PIN domain
LEHADEAE_03029 8.9e-116 sigH K Belongs to the sigma-70 factor family
LEHADEAE_03030 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LEHADEAE_03031 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
LEHADEAE_03032 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LEHADEAE_03033 1.2e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LEHADEAE_03034 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LEHADEAE_03035 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LEHADEAE_03036 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
LEHADEAE_03037 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEHADEAE_03038 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEHADEAE_03039 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
LEHADEAE_03040 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LEHADEAE_03041 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LEHADEAE_03042 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LEHADEAE_03043 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LEHADEAE_03044 6.2e-182 ybaC 3.4.11.5 S Alpha/beta hydrolase family
LEHADEAE_03045 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LEHADEAE_03046 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LEHADEAE_03047 3e-105 rplD J Forms part of the polypeptide exit tunnel
LEHADEAE_03048 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LEHADEAE_03049 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LEHADEAE_03050 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LEHADEAE_03051 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LEHADEAE_03052 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LEHADEAE_03053 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LEHADEAE_03054 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
LEHADEAE_03055 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LEHADEAE_03056 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LEHADEAE_03057 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LEHADEAE_03058 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LEHADEAE_03059 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LEHADEAE_03060 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LEHADEAE_03061 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LEHADEAE_03062 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LEHADEAE_03063 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LEHADEAE_03064 1.9e-23 rpmD J Ribosomal protein L30
LEHADEAE_03065 4.1e-72 rplO J binds to the 23S rRNA
LEHADEAE_03066 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LEHADEAE_03067 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LEHADEAE_03068 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
LEHADEAE_03069 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LEHADEAE_03070 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LEHADEAE_03071 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LEHADEAE_03072 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LEHADEAE_03073 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LEHADEAE_03074 4.7e-58 rplQ J Ribosomal protein L17
LEHADEAE_03075 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEHADEAE_03076 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEHADEAE_03077 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LEHADEAE_03078 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LEHADEAE_03079 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LEHADEAE_03080 6.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
LEHADEAE_03081 3.1e-144 ybaJ Q Methyltransferase domain
LEHADEAE_03082 1.4e-83 yizA S Damage-inducible protein DinB
LEHADEAE_03083 1.4e-77 ybaK S Protein of unknown function (DUF2521)
LEHADEAE_03084 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LEHADEAE_03085 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LEHADEAE_03086 1.7e-75 gerD
LEHADEAE_03087 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
LEHADEAE_03088 2.1e-132 pdaB 3.5.1.104 G Polysaccharide deacetylase
LEHADEAE_03091 3.4e-39 S COG NOG14552 non supervised orthologous group
LEHADEAE_03092 9.4e-220 glcP G Major Facilitator Superfamily
LEHADEAE_03093 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LEHADEAE_03094 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
LEHADEAE_03095 4.4e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
LEHADEAE_03096 5.1e-225 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
LEHADEAE_03097 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
LEHADEAE_03098 6e-108 ybbA S Putative esterase
LEHADEAE_03099 4e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEHADEAE_03100 1.4e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LEHADEAE_03101 2e-172 feuA P Iron-uptake system-binding protein
LEHADEAE_03102 1.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
LEHADEAE_03103 8.6e-237 ybbC 3.2.1.52 S protein conserved in bacteria
LEHADEAE_03104 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
LEHADEAE_03105 5.8e-244 yfeW 3.4.16.4 V Belongs to the UPF0214 family
LEHADEAE_03106 3.5e-239 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LEHADEAE_03107 2.4e-159 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LEHADEAE_03108 7.7e-85 ybbJ J acetyltransferase
LEHADEAE_03109 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
LEHADEAE_03110 2.5e-256 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_03111 1e-265 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
LEHADEAE_03112 5.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
LEHADEAE_03113 8.7e-246 yoeA V MATE efflux family protein
LEHADEAE_03114 2.9e-96 yoeB S IseA DL-endopeptidase inhibitor
LEHADEAE_03117 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
LEHADEAE_03118 1.3e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LEHADEAE_03119 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LEHADEAE_03120 1.3e-223 ybbR S protein conserved in bacteria
LEHADEAE_03121 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LEHADEAE_03122 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LEHADEAE_03123 3.8e-154 V ATPases associated with a variety of cellular activities
LEHADEAE_03124 3.7e-106 S ABC-2 family transporter protein
LEHADEAE_03125 7.3e-100 ybdN
LEHADEAE_03126 1.2e-131 ybdO S Domain of unknown function (DUF4885)
LEHADEAE_03127 3.6e-162 dkgB S Aldo/keto reductase family
LEHADEAE_03128 2.9e-93 yxaC M effector of murein hydrolase
LEHADEAE_03129 6.9e-52 S LrgA family
LEHADEAE_03130 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
LEHADEAE_03131 3.1e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
LEHADEAE_03132 2.7e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LEHADEAE_03133 8.9e-196 T COG4585 Signal transduction histidine kinase
LEHADEAE_03134 3.2e-110 KT LuxR family transcriptional regulator
LEHADEAE_03135 3e-165 V COG1131 ABC-type multidrug transport system, ATPase component
LEHADEAE_03136 6e-203 V COG0842 ABC-type multidrug transport system, permease component
LEHADEAE_03137 1.4e-193 V ABC-2 family transporter protein
LEHADEAE_03138 9.2e-23
LEHADEAE_03139 8.5e-76 S Domain of unknown function (DUF4879)
LEHADEAE_03140 7.5e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
LEHADEAE_03141 2.3e-106 yqeB
LEHADEAE_03142 9.2e-40 ybyB
LEHADEAE_03143 5.5e-292 ybeC E amino acid
LEHADEAE_03144 3.7e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEHADEAE_03145 1.7e-259 glpT G -transporter
LEHADEAE_03146 1e-16 S Protein of unknown function (DUF2651)
LEHADEAE_03147 1.6e-210 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
LEHADEAE_03149 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
LEHADEAE_03150 9.2e-32
LEHADEAE_03151 1.2e-82 K Helix-turn-helix XRE-family like proteins
LEHADEAE_03152 2.4e-195 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
LEHADEAE_03153 1.2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LEHADEAE_03154 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LEHADEAE_03155 1.9e-86 ybfM S SNARE associated Golgi protein
LEHADEAE_03156 4.7e-151 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LEHADEAE_03157 6.1e-42 ybfN
LEHADEAE_03158 2.5e-191 yceA S Belongs to the UPF0176 family
LEHADEAE_03159 1.3e-213 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LEHADEAE_03160 1.4e-198 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LEHADEAE_03161 1.5e-256 mmuP E amino acid
LEHADEAE_03162 1.6e-179 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
LEHADEAE_03163 2.7e-258 agcS E Sodium alanine symporter
LEHADEAE_03164 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
LEHADEAE_03165 3.1e-205 phoQ 2.7.13.3 T Histidine kinase
LEHADEAE_03166 7.4e-172 glnL T Regulator
LEHADEAE_03167 1.3e-125 ycbJ S Macrolide 2'-phosphotransferase
LEHADEAE_03168 1.2e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
LEHADEAE_03169 8.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEHADEAE_03170 4.5e-109 ydfN C nitroreductase
LEHADEAE_03171 4.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
LEHADEAE_03172 1.5e-62 mhqP S DoxX
LEHADEAE_03173 2.4e-56 traF CO Thioredoxin
LEHADEAE_03174 5.6e-62 ycbP S Protein of unknown function (DUF2512)
LEHADEAE_03175 5.3e-77 sleB 3.5.1.28 M Cell wall
LEHADEAE_03176 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
LEHADEAE_03177 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LEHADEAE_03178 1.4e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LEHADEAE_03179 7.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LEHADEAE_03180 1.3e-204 ycbU E Selenocysteine lyase
LEHADEAE_03181 1e-241 lmrB EGP the major facilitator superfamily
LEHADEAE_03182 1e-99 yxaF K Transcriptional regulator
LEHADEAE_03183 1.9e-195 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LEHADEAE_03184 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LEHADEAE_03185 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
LEHADEAE_03186 3.1e-170 yccK C Aldo keto reductase
LEHADEAE_03187 1.5e-175 ycdA S Domain of unknown function (DUF5105)
LEHADEAE_03188 1.5e-253 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
LEHADEAE_03189 1.3e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
LEHADEAE_03190 8.4e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
LEHADEAE_03191 1e-188 S response regulator aspartate phosphatase
LEHADEAE_03192 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
LEHADEAE_03193 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
LEHADEAE_03194 2.2e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
LEHADEAE_03195 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LEHADEAE_03196 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LEHADEAE_03197 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LEHADEAE_03198 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
LEHADEAE_03199 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
LEHADEAE_03200 6.7e-107 yceE T proteins involved in stress response, homologs of TerZ and
LEHADEAE_03201 3.7e-137 terC P Protein of unknown function (DUF475)
LEHADEAE_03202 0.0 yceG S Putative component of 'biosynthetic module'
LEHADEAE_03203 2.3e-193 yceH P Belongs to the TelA family
LEHADEAE_03204 9.9e-214 naiP P Uncharacterised MFS-type transporter YbfB
LEHADEAE_03205 3.9e-229 proV 3.6.3.32 E glycine betaine
LEHADEAE_03206 1.6e-138 opuAB P glycine betaine
LEHADEAE_03207 1.5e-163 opuAC E glycine betaine
LEHADEAE_03208 2.4e-209 amhX S amidohydrolase
LEHADEAE_03209 2.5e-227 ycgA S Membrane
LEHADEAE_03210 1.5e-80 ycgB
LEHADEAE_03211 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
LEHADEAE_03212 5.9e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LEHADEAE_03213 8.1e-261 mdr EGP Major facilitator Superfamily
LEHADEAE_03214 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
LEHADEAE_03215 3e-113 ycgF E Lysine exporter protein LysE YggA
LEHADEAE_03216 1.3e-150 yqcI S YqcI/YcgG family
LEHADEAE_03217 5.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
LEHADEAE_03218 1.3e-113 ycgI S Domain of unknown function (DUF1989)
LEHADEAE_03219 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LEHADEAE_03221 4.7e-108 tmrB S AAA domain
LEHADEAE_03222 2.5e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
LEHADEAE_03223 4.8e-222 G COG0477 Permeases of the major facilitator superfamily
LEHADEAE_03224 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LEHADEAE_03225 6.5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
LEHADEAE_03226 2e-146 ycgL S Predicted nucleotidyltransferase
LEHADEAE_03227 8.7e-170 ycgM E Proline dehydrogenase
LEHADEAE_03228 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LEHADEAE_03229 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LEHADEAE_03230 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
LEHADEAE_03231 3.2e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LEHADEAE_03232 1.1e-275 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LEHADEAE_03233 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
LEHADEAE_03234 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LEHADEAE_03235 4.6e-227 yciC S GTPases (G3E family)
LEHADEAE_03236 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LEHADEAE_03237 4.8e-73 yckC S membrane
LEHADEAE_03238 3.9e-48 S Protein of unknown function (DUF2680)
LEHADEAE_03239 9e-11 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEHADEAE_03240 5e-34 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LEHADEAE_03241 5.1e-66 nin S Competence protein J (ComJ)
LEHADEAE_03242 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
LEHADEAE_03243 1.6e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
LEHADEAE_03244 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
LEHADEAE_03245 2.6e-61 hxlR K transcriptional
LEHADEAE_03246 2.2e-78 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_03247 7.7e-39 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_03248 1e-20 pksJ Q Polyketide synthase of type I
LEHADEAE_03249 1.1e-127 IQ reductase
LEHADEAE_03250 1.7e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEHADEAE_03253 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LEHADEAE_03254 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
LEHADEAE_03255 1.1e-161 K LysR substrate binding domain
LEHADEAE_03256 1.6e-49 S GlpM protein
LEHADEAE_03257 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LEHADEAE_03258 3.7e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LEHADEAE_03259 2.6e-10 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LEHADEAE_03260 2.3e-170 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LEHADEAE_03261 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LEHADEAE_03262 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LEHADEAE_03263 8.1e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LEHADEAE_03264 2.4e-25 yqzJ
LEHADEAE_03265 5e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LEHADEAE_03266 1.8e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
LEHADEAE_03267 3.2e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LEHADEAE_03268 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
LEHADEAE_03270 3.1e-95 yqjB S protein conserved in bacteria
LEHADEAE_03271 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
LEHADEAE_03272 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEHADEAE_03273 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
LEHADEAE_03274 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
LEHADEAE_03275 1e-75 yqiW S Belongs to the UPF0403 family
LEHADEAE_03276 1.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LEHADEAE_03277 6.8e-189 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LEHADEAE_03278 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LEHADEAE_03279 2.1e-161 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LEHADEAE_03280 8.6e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LEHADEAE_03281 1.6e-205 buk 2.7.2.7 C Belongs to the acetokinase family
LEHADEAE_03282 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
LEHADEAE_03283 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
LEHADEAE_03284 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
LEHADEAE_03285 3.2e-34 yqzF S Protein of unknown function (DUF2627)
LEHADEAE_03286 2.4e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LEHADEAE_03287 8.3e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
LEHADEAE_03288 7.2e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
LEHADEAE_03289 1.5e-203 mmgC I acyl-CoA dehydrogenase
LEHADEAE_03290 2.5e-155 hbdA 1.1.1.157 I Dehydrogenase
LEHADEAE_03291 1.4e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
LEHADEAE_03292 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LEHADEAE_03293 8.8e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
LEHADEAE_03294 2.1e-16
LEHADEAE_03295 4.5e-101 ytaF P Probably functions as a manganese efflux pump
LEHADEAE_03296 2.6e-112 K Protein of unknown function (DUF1232)
LEHADEAE_03298 9.2e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LEHADEAE_03301 7.5e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LEHADEAE_03302 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LEHADEAE_03303 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
LEHADEAE_03304 7.9e-305 recN L May be involved in recombinational repair of damaged DNA
LEHADEAE_03305 3.9e-78 argR K Regulates arginine biosynthesis genes
LEHADEAE_03306 1.6e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
LEHADEAE_03307 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LEHADEAE_03308 2.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LEHADEAE_03309 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEHADEAE_03310 3e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LEHADEAE_03311 5.7e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LEHADEAE_03312 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LEHADEAE_03313 8.1e-67 yqhY S protein conserved in bacteria
LEHADEAE_03314 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LEHADEAE_03315 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LEHADEAE_03316 2.5e-62 spoIIIAH S SpoIIIAH-like protein
LEHADEAE_03317 1.1e-116 spoIIIAG S stage III sporulation protein AG
LEHADEAE_03318 2.6e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
LEHADEAE_03319 6.3e-200 spoIIIAE S stage III sporulation protein AE
LEHADEAE_03320 2.5e-41 spoIIIAD S Stage III sporulation protein AD
LEHADEAE_03321 7.6e-29 spoIIIAC S stage III sporulation protein AC
LEHADEAE_03322 1.7e-82 spoIIIAB S Stage III sporulation protein
LEHADEAE_03323 5.5e-172 spoIIIAA S stage III sporulation protein AA
LEHADEAE_03324 1.8e-36 yqhV S Protein of unknown function (DUF2619)
LEHADEAE_03325 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LEHADEAE_03326 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LEHADEAE_03327 3.7e-88 yqhR S Conserved membrane protein YqhR
LEHADEAE_03328 8e-174 yqhQ S Protein of unknown function (DUF1385)
LEHADEAE_03329 5.8e-62 yqhP
LEHADEAE_03330 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
LEHADEAE_03331 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LEHADEAE_03332 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LEHADEAE_03333 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
LEHADEAE_03334 5.9e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEHADEAE_03335 1.1e-250 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LEHADEAE_03336 5.7e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
LEHADEAE_03337 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LEHADEAE_03338 5.5e-152 yqhG S Bacterial protein YqhG of unknown function
LEHADEAE_03339 5.2e-23 sinI S Anti-repressor SinI
LEHADEAE_03340 7.8e-55 sinR K transcriptional
LEHADEAE_03341 1.6e-140 tasA S Cell division protein FtsN
LEHADEAE_03342 3.5e-71 sipW 3.4.21.89 U Signal peptidase
LEHADEAE_03343 2.7e-120 yqxM
LEHADEAE_03344 1.1e-53 yqzG S Protein of unknown function (DUF3889)
LEHADEAE_03345 2.3e-26 yqzE S YqzE-like protein
LEHADEAE_03346 2.1e-61 S ComG operon protein 7
LEHADEAE_03347 2.5e-65 comGF U Putative Competence protein ComGF
LEHADEAE_03348 2.6e-20 comGE
LEHADEAE_03349 1.5e-71 gspH NU Tfp pilus assembly protein FimT
LEHADEAE_03350 8.9e-50 comGC U Required for transformation and DNA binding
LEHADEAE_03351 4.6e-183 comGB NU COG1459 Type II secretory pathway, component PulF
LEHADEAE_03352 2.3e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LEHADEAE_03353 4.5e-185 corA P Mg2 transporter protein
LEHADEAE_03354 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LEHADEAE_03355 2.5e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LEHADEAE_03357 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
LEHADEAE_03358 3.1e-37 yqgY S Protein of unknown function (DUF2626)
LEHADEAE_03359 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LEHADEAE_03360 1.2e-19 yqgW S Protein of unknown function (DUF2759)
LEHADEAE_03361 4.5e-49 yqgV S Thiamine-binding protein
LEHADEAE_03362 3.3e-197 yqgU
LEHADEAE_03363 2.4e-217 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
LEHADEAE_03364 7.5e-180 glcK 2.7.1.2 G Glucokinase
LEHADEAE_03365 6.5e-28 yqgQ S Protein conserved in bacteria
LEHADEAE_03366 1e-230 nhaC C Na H antiporter
LEHADEAE_03367 4e-07 yqgO
LEHADEAE_03368 1e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LEHADEAE_03369 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LEHADEAE_03370 2.3e-49 yqzD
LEHADEAE_03371 3.2e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEHADEAE_03372 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEHADEAE_03373 6.1e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LEHADEAE_03374 2.9e-154 pstA P Phosphate transport system permease
LEHADEAE_03375 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
LEHADEAE_03376 7.6e-158 pstS P Phosphate
LEHADEAE_03377 0.0 pbpA 3.4.16.4 M penicillin-binding protein
LEHADEAE_03378 3.4e-228 yqgE EGP Major facilitator superfamily
LEHADEAE_03379 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
LEHADEAE_03380 2.9e-71 yqgC S protein conserved in bacteria
LEHADEAE_03381 1.1e-130 yqgB S Protein of unknown function (DUF1189)
LEHADEAE_03382 3.1e-47 yqfZ M LysM domain
LEHADEAE_03383 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LEHADEAE_03384 2.3e-52 yqfX S membrane
LEHADEAE_03385 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
LEHADEAE_03386 2.9e-72 zur P Belongs to the Fur family
LEHADEAE_03387 5.3e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LEHADEAE_03388 9.3e-37 yqfT S Protein of unknown function (DUF2624)
LEHADEAE_03389 1.4e-164 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LEHADEAE_03390 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LEHADEAE_03391 3.7e-43 yqfQ S YqfQ-like protein
LEHADEAE_03392 2.5e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LEHADEAE_03393 2.4e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LEHADEAE_03394 9.9e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
LEHADEAE_03395 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
LEHADEAE_03396 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LEHADEAE_03397 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LEHADEAE_03398 1.3e-87 yaiI S Belongs to the UPF0178 family
LEHADEAE_03399 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LEHADEAE_03400 4.5e-112 ccpN K CBS domain
LEHADEAE_03401 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LEHADEAE_03402 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LEHADEAE_03403 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
LEHADEAE_03404 1.8e-16 S YqzL-like protein
LEHADEAE_03405 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LEHADEAE_03406 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LEHADEAE_03407 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LEHADEAE_03408 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LEHADEAE_03409 0.0 yqfF S membrane-associated HD superfamily hydrolase
LEHADEAE_03410 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
LEHADEAE_03411 5.7e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
LEHADEAE_03412 9.3e-46 yqfC S sporulation protein YqfC
LEHADEAE_03413 1.9e-42 yqfB
LEHADEAE_03414 3.8e-118 yqfA S UPF0365 protein
LEHADEAE_03415 2.2e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
LEHADEAE_03416 8e-68 yqeY S Yqey-like protein
LEHADEAE_03417 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LEHADEAE_03418 4.8e-155 yqeW P COG1283 Na phosphate symporter
LEHADEAE_03419 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
LEHADEAE_03420 5.1e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LEHADEAE_03421 6.6e-173 prmA J Methylates ribosomal protein L11
LEHADEAE_03422 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LEHADEAE_03423 0.0 dnaK O Heat shock 70 kDa protein
LEHADEAE_03424 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LEHADEAE_03425 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LEHADEAE_03426 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
LEHADEAE_03427 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LEHADEAE_03428 2.5e-53 yqxA S Protein of unknown function (DUF3679)
LEHADEAE_03429 3.5e-219 spoIIP M stage II sporulation protein P
LEHADEAE_03430 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LEHADEAE_03431 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
LEHADEAE_03432 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
LEHADEAE_03433 0.0 comEC S Competence protein ComEC
LEHADEAE_03434 8e-105 comEB 3.5.4.12 F ComE operon protein 2
LEHADEAE_03435 8.9e-102 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
LEHADEAE_03436 3.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LEHADEAE_03437 1.1e-138 yqeM Q Methyltransferase
LEHADEAE_03438 2.2e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LEHADEAE_03439 2.5e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LEHADEAE_03440 2.1e-105 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LEHADEAE_03441 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
LEHADEAE_03442 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LEHADEAE_03443 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LEHADEAE_03444 7.6e-94 yqeG S hydrolase of the HAD superfamily
LEHADEAE_03446 2.5e-138 yqeF E GDSL-like Lipase/Acylhydrolase
LEHADEAE_03447 2.9e-139 3.5.1.104 G Polysaccharide deacetylase
LEHADEAE_03448 8e-106 yqeD S SNARE associated Golgi protein
LEHADEAE_03449 7e-210 EGP Major facilitator Superfamily
LEHADEAE_03450 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LEHADEAE_03451 1.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
LEHADEAE_03452 3.6e-91 K Transcriptional regulator PadR-like family
LEHADEAE_03453 1e-146 ydeE K AraC family transcriptional regulator
LEHADEAE_03454 4.1e-95 adk 2.7.4.3 F adenylate kinase activity
LEHADEAE_03455 1.1e-219 tetL EGP Major facilitator Superfamily
LEHADEAE_03457 1.3e-24 L nucleic acid phosphodiester bond hydrolysis
LEHADEAE_03459 1.3e-96 est S Lecithin:cholesterol acyltransferase
LEHADEAE_03460 4.1e-21
LEHADEAE_03461 2.8e-39 yyaR K acetyltransferase
LEHADEAE_03462 1.5e-91 yrdA S DinB family
LEHADEAE_03463 9.5e-144 S hydrolase
LEHADEAE_03464 1.1e-144 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
LEHADEAE_03465 7.8e-129 glvR K Helix-turn-helix domain, rpiR family
LEHADEAE_03466 7.6e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
LEHADEAE_03467 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
LEHADEAE_03468 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
LEHADEAE_03469 2.5e-180 romA S Beta-lactamase superfamily domain
LEHADEAE_03470 1.7e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LEHADEAE_03471 4.1e-164 yybE K Transcriptional regulator
LEHADEAE_03472 1.9e-212 ynfM EGP Major facilitator Superfamily
LEHADEAE_03473 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LEHADEAE_03474 1.7e-99 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
LEHADEAE_03475 7.1e-79 yrhH Q methyltransferase
LEHADEAE_03477 8e-143 focA P Formate nitrite
LEHADEAE_03478 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
LEHADEAE_03479 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
LEHADEAE_03480 7e-81 yrhD S Protein of unknown function (DUF1641)
LEHADEAE_03481 5.1e-34 yrhC S YrhC-like protein
LEHADEAE_03482 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LEHADEAE_03483 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
LEHADEAE_03484 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LEHADEAE_03485 2.3e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
LEHADEAE_03486 5.3e-27 yrzA S Protein of unknown function (DUF2536)
LEHADEAE_03487 8.1e-70 yrrS S Protein of unknown function (DUF1510)
LEHADEAE_03488 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
LEHADEAE_03489 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LEHADEAE_03490 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
LEHADEAE_03491 6.1e-246 yegQ O COG0826 Collagenase and related proteases
LEHADEAE_03492 2.9e-173 yegQ O Peptidase U32
LEHADEAE_03493 6.1e-117 yrrM 2.1.1.104 S O-methyltransferase
LEHADEAE_03494 4.1e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LEHADEAE_03495 7.1e-46 yrzB S Belongs to the UPF0473 family
LEHADEAE_03496 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LEHADEAE_03497 8.5e-41 yrzL S Belongs to the UPF0297 family
LEHADEAE_03498 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LEHADEAE_03499 2e-162 yrrI S AI-2E family transporter
LEHADEAE_03500 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LEHADEAE_03501 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
LEHADEAE_03502 6.1e-109 gluC P ABC transporter
LEHADEAE_03503 4.9e-106 glnP P ABC transporter
LEHADEAE_03504 2.1e-08 S Protein of unknown function (DUF3918)
LEHADEAE_03505 2.9e-30 yrzR
LEHADEAE_03506 3.4e-82 yrrD S protein conserved in bacteria
LEHADEAE_03507 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LEHADEAE_03508 1.7e-18 S COG0457 FOG TPR repeat
LEHADEAE_03509 2e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LEHADEAE_03510 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
LEHADEAE_03511 7.8e-64 cymR K Transcriptional regulator
LEHADEAE_03512 2.8e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LEHADEAE_03513 1.4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LEHADEAE_03514 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LEHADEAE_03515 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
LEHADEAE_03518 1.4e-273 lytH 3.5.1.28 M COG3103 SH3 domain protein
LEHADEAE_03519 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LEHADEAE_03520 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LEHADEAE_03521 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LEHADEAE_03522 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LEHADEAE_03523 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
LEHADEAE_03524 7.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
LEHADEAE_03525 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LEHADEAE_03526 8.5e-50 yrzD S Post-transcriptional regulator
LEHADEAE_03527 4.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEHADEAE_03528 9.5e-110 yrbG S membrane
LEHADEAE_03529 2.4e-60 yrzE S Protein of unknown function (DUF3792)
LEHADEAE_03530 2.5e-37 yajC U Preprotein translocase subunit YajC
LEHADEAE_03531 1.2e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LEHADEAE_03532 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LEHADEAE_03533 1.6e-20 yrzS S Protein of unknown function (DUF2905)
LEHADEAE_03534 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LEHADEAE_03535 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LEHADEAE_03536 3.7e-93 bofC S BofC C-terminal domain
LEHADEAE_03538 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LEHADEAE_03539 1.2e-126 safA M spore coat assembly protein SafA
LEHADEAE_03540 5.9e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LEHADEAE_03541 3.2e-150 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
LEHADEAE_03542 5.7e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
LEHADEAE_03543 2.5e-222 nifS 2.8.1.7 E Cysteine desulfurase
LEHADEAE_03544 1.3e-93 niaR S small molecule binding protein (contains 3H domain)
LEHADEAE_03545 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
LEHADEAE_03546 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
LEHADEAE_03547 2.4e-234 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LEHADEAE_03548 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
LEHADEAE_03549 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LEHADEAE_03550 3.2e-56 ysxB J ribosomal protein
LEHADEAE_03551 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
LEHADEAE_03552 1.2e-160 spoIVFB S Stage IV sporulation protein
LEHADEAE_03553 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
LEHADEAE_03554 2.3e-142 minD D Belongs to the ParA family
LEHADEAE_03555 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LEHADEAE_03556 5.4e-84 mreD M shape-determining protein
LEHADEAE_03557 3.6e-157 mreC M Involved in formation and maintenance of cell shape
LEHADEAE_03558 5.8e-183 mreB D Rod shape-determining protein MreB
LEHADEAE_03559 5.3e-127 radC E Belongs to the UPF0758 family
LEHADEAE_03560 9.5e-98 maf D septum formation protein Maf
LEHADEAE_03561 2.8e-137 spoIIB S Sporulation related domain
LEHADEAE_03562 2.5e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LEHADEAE_03563 8.1e-238 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LEHADEAE_03564 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LEHADEAE_03565 2.1e-25
LEHADEAE_03566 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LEHADEAE_03567 2.2e-225 spoVID M stage VI sporulation protein D
LEHADEAE_03568 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LEHADEAE_03569 8.7e-184 hemB 4.2.1.24 H Belongs to the ALAD family
LEHADEAE_03570 1.6e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LEHADEAE_03571 2e-129 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LEHADEAE_03572 1.6e-23 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LEHADEAE_03573 1e-145 hemX O cytochrome C
LEHADEAE_03574 3.8e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LEHADEAE_03575 3.8e-87 ysxD
LEHADEAE_03576 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
LEHADEAE_03577 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LEHADEAE_03578 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
LEHADEAE_03579 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LEHADEAE_03580 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LEHADEAE_03581 2.3e-187 ysoA H Tetratricopeptide repeat
LEHADEAE_03582 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEHADEAE_03583 2.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LEHADEAE_03584 1.1e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LEHADEAE_03585 1.8e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LEHADEAE_03586 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LEHADEAE_03587 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
LEHADEAE_03588 0.0 ilvB 2.2.1.6 E Acetolactate synthase
LEHADEAE_03593 5.9e-91 ysnB S Phosphoesterase
LEHADEAE_03594 4.2e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LEHADEAE_03595 3.4e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LEHADEAE_03596 1.5e-197 gerM S COG5401 Spore germination protein
LEHADEAE_03597 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LEHADEAE_03598 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
LEHADEAE_03599 2e-30 gerE K Transcriptional regulator
LEHADEAE_03600 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
LEHADEAE_03601 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LEHADEAE_03602 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LEHADEAE_03603 2.4e-107 sdhC C succinate dehydrogenase
LEHADEAE_03604 2e-79 yslB S Protein of unknown function (DUF2507)
LEHADEAE_03605 9.2e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LEHADEAE_03606 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LEHADEAE_03607 2.5e-52 trxA O Belongs to the thioredoxin family
LEHADEAE_03608 4.3e-299 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
LEHADEAE_03609 6e-177 etfA C Electron transfer flavoprotein
LEHADEAE_03610 1.7e-137 etfB C Electron transfer flavoprotein
LEHADEAE_03611 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LEHADEAE_03612 1e-102 fadR K Transcriptional regulator
LEHADEAE_03613 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LEHADEAE_03614 8.6e-89 ywbB S Protein of unknown function (DUF2711)
LEHADEAE_03615 4.7e-67 yshE S membrane
LEHADEAE_03616 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LEHADEAE_03617 0.0 polX L COG1796 DNA polymerase IV (family X)
LEHADEAE_03618 3.6e-83 cvpA S membrane protein, required for colicin V production
LEHADEAE_03619 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LEHADEAE_03620 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LEHADEAE_03621 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEHADEAE_03622 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LEHADEAE_03623 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LEHADEAE_03624 2e-32 sspI S Belongs to the SspI family
LEHADEAE_03625 2.7e-202 ysfB KT regulator
LEHADEAE_03626 1.6e-258 glcD 1.1.3.15 C FAD binding domain
LEHADEAE_03627 1.3e-254 glcF C Glycolate oxidase
LEHADEAE_03628 0.0 cstA T Carbon starvation protein
LEHADEAE_03629 2.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
LEHADEAE_03630 1.2e-144 araQ G transport system permease
LEHADEAE_03631 1.1e-167 araP P PFAM binding-protein-dependent transport systems inner membrane component
LEHADEAE_03632 2.9e-251 araN G carbohydrate transport
LEHADEAE_03633 1.2e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LEHADEAE_03634 7.8e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LEHADEAE_03635 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LEHADEAE_03636 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
LEHADEAE_03637 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
LEHADEAE_03638 6.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LEHADEAE_03639 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
LEHADEAE_03640 1.9e-65 ysdB S Sigma-w pathway protein YsdB
LEHADEAE_03641 2.6e-42 ysdA S Membrane
LEHADEAE_03642 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LEHADEAE_03643 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LEHADEAE_03644 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LEHADEAE_03645 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LEHADEAE_03646 2.9e-38 lrgA S effector of murein hydrolase LrgA
LEHADEAE_03647 5.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
LEHADEAE_03648 0.0 lytS 2.7.13.3 T Histidine kinase
LEHADEAE_03649 3.9e-150 ysaA S HAD-hyrolase-like
LEHADEAE_03650 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LEHADEAE_03651 6.7e-153 ytxC S YtxC-like family
LEHADEAE_03652 2.1e-106 ytxB S SNARE associated Golgi protein
LEHADEAE_03653 9.5e-172 dnaI L Primosomal protein DnaI
LEHADEAE_03654 3.1e-251 dnaB L Membrane attachment protein
LEHADEAE_03655 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LEHADEAE_03656 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LEHADEAE_03657 9.7e-194 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LEHADEAE_03658 2e-67 ytcD K Transcriptional regulator
LEHADEAE_03659 4.5e-206 ytbD EGP Major facilitator Superfamily
LEHADEAE_03660 1.7e-159 ytbE S reductase
LEHADEAE_03661 6.8e-99 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LEHADEAE_03662 2.1e-106 ytaF P Probably functions as a manganese efflux pump
LEHADEAE_03663 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LEHADEAE_03664 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LEHADEAE_03665 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
LEHADEAE_03666 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEHADEAE_03667 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
LEHADEAE_03668 1.2e-241 icd 1.1.1.42 C isocitrate
LEHADEAE_03669 2.8e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
LEHADEAE_03670 1.4e-39 yjdF S Protein of unknown function (DUF2992)
LEHADEAE_03671 1.1e-72 yeaL S membrane
LEHADEAE_03672 6.9e-193 ytvI S sporulation integral membrane protein YtvI
LEHADEAE_03673 3.5e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
LEHADEAE_03674 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LEHADEAE_03675 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LEHADEAE_03676 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LEHADEAE_03677 4.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LEHADEAE_03678 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
LEHADEAE_03679 0.0 dnaE 2.7.7.7 L DNA polymerase
LEHADEAE_03680 3.2e-56 ytrH S Sporulation protein YtrH
LEHADEAE_03681 4.3e-86 ytrI
LEHADEAE_03682 5.8e-23
LEHADEAE_03683 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
LEHADEAE_03684 1.5e-46 ytpI S YtpI-like protein
LEHADEAE_03685 2.2e-235 ytoI K transcriptional regulator containing CBS domains
LEHADEAE_03686 1.3e-128 ytkL S Belongs to the UPF0173 family
LEHADEAE_03687 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LEHADEAE_03689 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
LEHADEAE_03690 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LEHADEAE_03691 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
LEHADEAE_03692 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LEHADEAE_03693 9.1e-181 ytxK 2.1.1.72 L DNA methylase
LEHADEAE_03694 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LEHADEAE_03695 1.6e-60 ytfJ S Sporulation protein YtfJ
LEHADEAE_03696 1e-93 ytfI S Protein of unknown function (DUF2953)
LEHADEAE_03697 4.5e-88 yteJ S RDD family
LEHADEAE_03698 6.4e-182 sppA OU signal peptide peptidase SppA
LEHADEAE_03699 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LEHADEAE_03700 0.0 ytcJ S amidohydrolase
LEHADEAE_03701 4.7e-304 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LEHADEAE_03702 3.9e-31 sspB S spore protein
LEHADEAE_03703 5.6e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LEHADEAE_03704 1.3e-207 iscS2 2.8.1.7 E Cysteine desulfurase
LEHADEAE_03705 2.9e-238 braB E Component of the transport system for branched-chain amino acids
LEHADEAE_03706 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LEHADEAE_03707 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LEHADEAE_03708 7.7e-109 yttP K Transcriptional regulator
LEHADEAE_03709 1.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
LEHADEAE_03710 2.3e-283 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
LEHADEAE_03711 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LEHADEAE_03712 2.3e-251 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LEHADEAE_03713 6.4e-99 yokH G SMI1 / KNR4 family
LEHADEAE_03714 5e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LEHADEAE_03715 2.5e-09
LEHADEAE_03716 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
LEHADEAE_03718 2.3e-136 E GDSL-like Lipase/Acylhydrolase family
LEHADEAE_03719 3.6e-149 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LEHADEAE_03720 2.8e-148 K Transcriptional regulator
LEHADEAE_03721 1e-108 azlC E AzlC protein
LEHADEAE_03722 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
LEHADEAE_03723 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LEHADEAE_03724 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LEHADEAE_03725 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LEHADEAE_03726 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
LEHADEAE_03727 1.1e-228 acuC BQ histone deacetylase
LEHADEAE_03728 3.7e-120 motS N Flagellar motor protein
LEHADEAE_03729 6.6e-145 motA N flagellar motor
LEHADEAE_03730 2.4e-181 ccpA K catabolite control protein A
LEHADEAE_03731 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LEHADEAE_03732 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
LEHADEAE_03733 1.7e-16 ytxH S COG4980 Gas vesicle protein
LEHADEAE_03734 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LEHADEAE_03735 5.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LEHADEAE_03736 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
LEHADEAE_03737 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LEHADEAE_03738 1.4e-147 ytpQ S Belongs to the UPF0354 family
LEHADEAE_03739 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LEHADEAE_03740 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
LEHADEAE_03741 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LEHADEAE_03742 1.7e-51 ytzB S small secreted protein
LEHADEAE_03743 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
LEHADEAE_03744 2.1e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
LEHADEAE_03745 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LEHADEAE_03746 3.5e-45 ytzH S YtzH-like protein
LEHADEAE_03747 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
LEHADEAE_03748 1.7e-176 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LEHADEAE_03749 1.7e-165 ytlQ
LEHADEAE_03750 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LEHADEAE_03751 3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LEHADEAE_03752 1.4e-267 pepV 3.5.1.18 E Dipeptidase
LEHADEAE_03753 1.3e-227 pbuO S permease
LEHADEAE_03754 1e-215 ythQ U Bacterial ABC transporter protein EcsB
LEHADEAE_03755 3.7e-128 ythP V ABC transporter
LEHADEAE_03756 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
LEHADEAE_03757 2.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LEHADEAE_03758 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LEHADEAE_03759 5.7e-236 ytfP S HI0933-like protein
LEHADEAE_03760 1.4e-281 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LEHADEAE_03761 9e-26 yteV S Sporulation protein Cse60
LEHADEAE_03762 2.8e-185 msmR K Transcriptional regulator
LEHADEAE_03763 4.9e-243 msmE G Bacterial extracellular solute-binding protein
LEHADEAE_03764 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
LEHADEAE_03765 5.3e-142 amyC P ABC transporter (permease)
LEHADEAE_03766 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LEHADEAE_03767 4.7e-79 M Acetyltransferase (GNAT) domain
LEHADEAE_03768 3.6e-51 ytwF P Sulfurtransferase
LEHADEAE_03769 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LEHADEAE_03770 1.2e-52 ytvB S Protein of unknown function (DUF4257)
LEHADEAE_03771 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LEHADEAE_03772 1.8e-207 yttB EGP Major facilitator Superfamily
LEHADEAE_03773 3.8e-109 ywaF S Integral membrane protein
LEHADEAE_03774 0.0 bceB V ABC transporter (permease)
LEHADEAE_03775 4.9e-134 bceA V ABC transporter, ATP-binding protein
LEHADEAE_03776 9.2e-170 T PhoQ Sensor
LEHADEAE_03777 3.3e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LEHADEAE_03778 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
LEHADEAE_03779 2.2e-125 ytrE V ABC transporter, ATP-binding protein
LEHADEAE_03780 6.8e-152
LEHADEAE_03781 8.5e-171 P ABC-2 family transporter protein
LEHADEAE_03782 5.9e-164 S ABC-2 family transporter protein
LEHADEAE_03783 1.9e-161 ytrB P abc transporter atp-binding protein
LEHADEAE_03784 3.9e-66 ytrA K GntR family transcriptional regulator
LEHADEAE_03786 7.4e-40 ytzC S Protein of unknown function (DUF2524)
LEHADEAE_03787 1.3e-304 IQ AMP-binding enzyme
LEHADEAE_03788 5.2e-201 K helix_turn_helix, Arsenical Resistance Operon Repressor
LEHADEAE_03789 0.0 Q Polyketide synthase of type I
LEHADEAE_03790 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_03791 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LEHADEAE_03792 3.2e-186 C Nitroreductase
LEHADEAE_03793 1.4e-127 nrsA Q Thioesterase domain
LEHADEAE_03794 4.1e-282 norB EGP COG0477 Permeases of the major facilitator superfamily
LEHADEAE_03795 1.1e-189 yhcC S Fe-S oxidoreductase
LEHADEAE_03796 9.7e-106 ytqB J Putative rRNA methylase
LEHADEAE_03798 1.5e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
LEHADEAE_03799 1.6e-210 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
LEHADEAE_03800 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
LEHADEAE_03801 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LEHADEAE_03802 6.3e-260 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
LEHADEAE_03803 0.0 asnB 6.3.5.4 E Asparagine synthase
LEHADEAE_03804 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LEHADEAE_03805 7.7e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LEHADEAE_03806 1.6e-38 ytmB S Protein of unknown function (DUF2584)
LEHADEAE_03807 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LEHADEAE_03808 8.9e-184 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LEHADEAE_03809 3.2e-144 ytlC P ABC transporter
LEHADEAE_03810 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LEHADEAE_03811 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
LEHADEAE_03812 5e-61 ytkC S Bacteriophage holin family
LEHADEAE_03813 7.8e-76 dps P Belongs to the Dps family
LEHADEAE_03815 6.7e-75 ytkA S YtkA-like
LEHADEAE_03816 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LEHADEAE_03817 1.2e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LEHADEAE_03818 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LEHADEAE_03819 7.9e-41 rpmE2 J Ribosomal protein L31
LEHADEAE_03820 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
LEHADEAE_03821 1.5e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LEHADEAE_03822 2e-23 S Domain of Unknown Function (DUF1540)
LEHADEAE_03823 3.5e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LEHADEAE_03824 4.1e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LEHADEAE_03825 2.1e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LEHADEAE_03826 2.7e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LEHADEAE_03827 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LEHADEAE_03828 5.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
LEHADEAE_03829 2.4e-130 dksA T COG1734 DnaK suppressor protein
LEHADEAE_03830 4.5e-77 tspO T membrane
LEHADEAE_03836 1.6e-08
LEHADEAE_03838 1.3e-09

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)