ORF_ID e_value Gene_name EC_number CAZy COGs Description
KMCOHGGH_00001 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KMCOHGGH_00002 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KMCOHGGH_00003 7.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KMCOHGGH_00004 2.4e-33 yaaA S S4 domain
KMCOHGGH_00005 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KMCOHGGH_00006 8.1e-38 yaaB S Domain of unknown function (DUF370)
KMCOHGGH_00007 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMCOHGGH_00008 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMCOHGGH_00009 3.4e-39 S COG NOG14552 non supervised orthologous group
KMCOHGGH_00012 7.5e-183 yaaC S YaaC-like Protein
KMCOHGGH_00013 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KMCOHGGH_00014 4e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KMCOHGGH_00015 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KMCOHGGH_00016 4.7e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KMCOHGGH_00017 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KMCOHGGH_00018 1e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KMCOHGGH_00019 1.3e-09
KMCOHGGH_00020 4.1e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KMCOHGGH_00021 4.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KMCOHGGH_00022 5.8e-212 yaaH M Glycoside Hydrolase Family
KMCOHGGH_00023 2.2e-99 yaaI Q COG1335 Amidases related to nicotinamidase
KMCOHGGH_00024 7.8e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KMCOHGGH_00025 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMCOHGGH_00026 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KMCOHGGH_00027 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KMCOHGGH_00028 3.6e-32 yaaL S Protein of unknown function (DUF2508)
KMCOHGGH_00029 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
KMCOHGGH_00030 3.4e-39 S COG NOG14552 non supervised orthologous group
KMCOHGGH_00033 2.2e-30 csfB S Inhibitor of sigma-G Gin
KMCOHGGH_00034 1.1e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KMCOHGGH_00035 1.1e-190 yaaN P Belongs to the TelA family
KMCOHGGH_00036 2.1e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KMCOHGGH_00037 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KMCOHGGH_00038 7.5e-55 yaaQ S protein conserved in bacteria
KMCOHGGH_00039 1.2e-71 yaaR S protein conserved in bacteria
KMCOHGGH_00040 1.3e-182 holB 2.7.7.7 L DNA polymerase III
KMCOHGGH_00041 8.8e-145 yaaT S stage 0 sporulation protein
KMCOHGGH_00042 7.7e-37 yabA L Involved in initiation control of chromosome replication
KMCOHGGH_00043 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
KMCOHGGH_00044 4.7e-48 yazA L endonuclease containing a URI domain
KMCOHGGH_00045 5.3e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KMCOHGGH_00046 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KMCOHGGH_00047 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KMCOHGGH_00048 7.6e-143 tatD L hydrolase, TatD
KMCOHGGH_00049 1.8e-232 rpfB GH23 T protein conserved in bacteria
KMCOHGGH_00050 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KMCOHGGH_00051 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KMCOHGGH_00052 8.4e-146 yabG S peptidase
KMCOHGGH_00053 7.8e-39 veg S protein conserved in bacteria
KMCOHGGH_00054 2.9e-27 sspF S DNA topological change
KMCOHGGH_00055 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KMCOHGGH_00056 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KMCOHGGH_00057 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KMCOHGGH_00058 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KMCOHGGH_00059 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KMCOHGGH_00060 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KMCOHGGH_00061 1e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KMCOHGGH_00062 9.4e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KMCOHGGH_00063 3.7e-40 yabK S Peptide ABC transporter permease
KMCOHGGH_00064 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KMCOHGGH_00065 6.2e-91 spoVT K stage V sporulation protein
KMCOHGGH_00066 3.5e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMCOHGGH_00067 2e-277 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KMCOHGGH_00068 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KMCOHGGH_00069 1.9e-49 yabP S Sporulation protein YabP
KMCOHGGH_00070 5.8e-104 yabQ S spore cortex biosynthesis protein
KMCOHGGH_00071 4.1e-57 divIC D Septum formation initiator
KMCOHGGH_00072 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KMCOHGGH_00075 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KMCOHGGH_00076 3.2e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
KMCOHGGH_00077 1.8e-184 KLT serine threonine protein kinase
KMCOHGGH_00078 1.3e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KMCOHGGH_00079 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KMCOHGGH_00080 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KMCOHGGH_00081 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KMCOHGGH_00082 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KMCOHGGH_00083 1.4e-156 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KMCOHGGH_00084 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KMCOHGGH_00085 1.4e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KMCOHGGH_00086 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KMCOHGGH_00087 1.2e-160 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KMCOHGGH_00088 3.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KMCOHGGH_00089 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KMCOHGGH_00090 9.9e-91 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KMCOHGGH_00091 4.5e-29 yazB K transcriptional
KMCOHGGH_00092 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KMCOHGGH_00093 6.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KMCOHGGH_00094 3.4e-39 S COG NOG14552 non supervised orthologous group
KMCOHGGH_00096 1.3e-07
KMCOHGGH_00099 2e-08
KMCOHGGH_00104 3.4e-39 S COG NOG14552 non supervised orthologous group
KMCOHGGH_00105 7.5e-77 ctsR K Belongs to the CtsR family
KMCOHGGH_00106 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KMCOHGGH_00107 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KMCOHGGH_00108 0.0 clpC O Belongs to the ClpA ClpB family
KMCOHGGH_00109 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KMCOHGGH_00110 6.4e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KMCOHGGH_00111 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KMCOHGGH_00112 2.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KMCOHGGH_00113 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KMCOHGGH_00114 8.1e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KMCOHGGH_00115 1e-116 cysE 2.3.1.30 E Serine acetyltransferase
KMCOHGGH_00116 3.1e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KMCOHGGH_00117 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KMCOHGGH_00118 1.3e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMCOHGGH_00119 4.2e-89 yacP S RNA-binding protein containing a PIN domain
KMCOHGGH_00120 8.9e-116 sigH K Belongs to the sigma-70 factor family
KMCOHGGH_00121 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KMCOHGGH_00122 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
KMCOHGGH_00123 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KMCOHGGH_00124 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KMCOHGGH_00125 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KMCOHGGH_00126 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KMCOHGGH_00127 9.7e-109 rsmC 2.1.1.172 J Methyltransferase
KMCOHGGH_00128 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMCOHGGH_00129 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMCOHGGH_00130 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KMCOHGGH_00131 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KMCOHGGH_00132 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KMCOHGGH_00133 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KMCOHGGH_00134 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KMCOHGGH_00135 1.5e-188 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KMCOHGGH_00136 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KMCOHGGH_00137 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KMCOHGGH_00138 8.8e-105 rplD J Forms part of the polypeptide exit tunnel
KMCOHGGH_00139 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KMCOHGGH_00140 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KMCOHGGH_00141 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KMCOHGGH_00142 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KMCOHGGH_00143 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KMCOHGGH_00144 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KMCOHGGH_00145 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KMCOHGGH_00146 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KMCOHGGH_00147 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KMCOHGGH_00148 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KMCOHGGH_00149 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KMCOHGGH_00150 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMCOHGGH_00151 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KMCOHGGH_00152 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KMCOHGGH_00153 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KMCOHGGH_00154 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KMCOHGGH_00155 1.9e-23 rpmD J Ribosomal protein L30
KMCOHGGH_00156 1.1e-72 rplO J binds to the 23S rRNA
KMCOHGGH_00157 1.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KMCOHGGH_00158 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KMCOHGGH_00159 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
KMCOHGGH_00160 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KMCOHGGH_00161 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KMCOHGGH_00162 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KMCOHGGH_00163 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KMCOHGGH_00164 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMCOHGGH_00165 4.7e-58 rplQ J Ribosomal protein L17
KMCOHGGH_00166 8.7e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMCOHGGH_00167 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMCOHGGH_00168 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMCOHGGH_00169 2.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KMCOHGGH_00170 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KMCOHGGH_00171 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KMCOHGGH_00172 8.2e-145 ybaJ Q Methyltransferase domain
KMCOHGGH_00173 5.9e-85 yizA S Damage-inducible protein DinB
KMCOHGGH_00174 1.7e-78 ybaK S Protein of unknown function (DUF2521)
KMCOHGGH_00175 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KMCOHGGH_00176 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KMCOHGGH_00177 7.6e-76 gerD
KMCOHGGH_00178 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KMCOHGGH_00179 1.4e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
KMCOHGGH_00180 3.4e-39 S COG NOG14552 non supervised orthologous group
KMCOHGGH_00183 1.6e-08
KMCOHGGH_00186 3.4e-39 S COG NOG14552 non supervised orthologous group
KMCOHGGH_00187 1.2e-219 glcP G Major Facilitator Superfamily
KMCOHGGH_00188 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMCOHGGH_00189 8.8e-181 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
KMCOHGGH_00190 1.1e-200 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
KMCOHGGH_00191 6e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KMCOHGGH_00192 1.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
KMCOHGGH_00193 1.9e-114 ybbA S Putative esterase
KMCOHGGH_00194 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMCOHGGH_00195 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMCOHGGH_00196 2e-172 feuA P Iron-uptake system-binding protein
KMCOHGGH_00197 0.0 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KMCOHGGH_00198 1.2e-238 ybbC 3.2.1.52 S protein conserved in bacteria
KMCOHGGH_00199 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KMCOHGGH_00200 2.3e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KMCOHGGH_00201 2.3e-238 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMCOHGGH_00202 9.8e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KMCOHGGH_00203 9.1e-86 ybbJ J acetyltransferase
KMCOHGGH_00204 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KMCOHGGH_00210 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KMCOHGGH_00211 7.7e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KMCOHGGH_00212 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KMCOHGGH_00213 1.3e-223 ybbR S protein conserved in bacteria
KMCOHGGH_00214 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KMCOHGGH_00215 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KMCOHGGH_00216 9.9e-155 V ATPases associated with a variety of cellular activities
KMCOHGGH_00217 2.3e-31 L COG2963 Transposase and inactivated derivatives
KMCOHGGH_00218 0.0 nrsA Q Polyketide synthase of type I
KMCOHGGH_00219 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_00220 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
KMCOHGGH_00221 0.0 Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KMCOHGGH_00222 1.3e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_00223 2e-183 T PhoQ Sensor
KMCOHGGH_00224 3.7e-137 V ABC transporter, ATP-binding protein
KMCOHGGH_00225 0.0 V ABC transporter (permease)
KMCOHGGH_00226 0.0 cusA V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KMCOHGGH_00227 7.3e-163 dkgB S Aldo/keto reductase family
KMCOHGGH_00228 1e-93 yxaC M effector of murein hydrolase
KMCOHGGH_00229 7.1e-52 S LrgA family
KMCOHGGH_00230 8.8e-72 yxaD K helix_turn_helix multiple antibiotic resistance protein
KMCOHGGH_00231 1.2e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KMCOHGGH_00232 2.1e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KMCOHGGH_00233 3.3e-203 T COG4585 Signal transduction histidine kinase
KMCOHGGH_00234 1.2e-109 KT LuxR family transcriptional regulator
KMCOHGGH_00235 6.4e-168 V COG1131 ABC-type multidrug transport system, ATPase component
KMCOHGGH_00236 2.8e-205 V COG0842 ABC-type multidrug transport system, permease component
KMCOHGGH_00237 2.9e-199 V ABC-2 family transporter protein
KMCOHGGH_00238 2.2e-24
KMCOHGGH_00239 4.5e-77 S Domain of unknown function (DUF4879)
KMCOHGGH_00240 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
KMCOHGGH_00241 5e-109 yqeB
KMCOHGGH_00242 9.2e-40 ybyB
KMCOHGGH_00243 2.5e-292 ybeC E amino acid
KMCOHGGH_00244 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KMCOHGGH_00245 1.7e-259 glpT G -transporter
KMCOHGGH_00246 1.3e-16 S Protein of unknown function (DUF2651)
KMCOHGGH_00247 1.9e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KMCOHGGH_00249 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
KMCOHGGH_00250 1.3e-30
KMCOHGGH_00251 1.2e-82 K Helix-turn-helix XRE-family like proteins
KMCOHGGH_00252 3.9e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KMCOHGGH_00253 4e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KMCOHGGH_00254 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KMCOHGGH_00255 1.9e-86 ybfM S SNARE associated Golgi protein
KMCOHGGH_00256 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KMCOHGGH_00257 1.2e-42 ybfN
KMCOHGGH_00258 8.6e-192 yceA S Belongs to the UPF0176 family
KMCOHGGH_00259 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMCOHGGH_00260 3.3e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KMCOHGGH_00261 6.1e-258 mmuP E amino acid
KMCOHGGH_00262 1.6e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KMCOHGGH_00263 2.7e-258 agcS E Sodium alanine symporter
KMCOHGGH_00264 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
KMCOHGGH_00265 2.9e-211 phoQ 2.7.13.3 T Histidine kinase
KMCOHGGH_00266 1.9e-172 glnL T Regulator
KMCOHGGH_00267 2.7e-29 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KMCOHGGH_00268 1.2e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMCOHGGH_00269 9.6e-112 ydfN C nitroreductase
KMCOHGGH_00270 8.1e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
KMCOHGGH_00271 9.8e-62 mhqP S DoxX
KMCOHGGH_00272 1.6e-55 traF CO Thioredoxin
KMCOHGGH_00273 5.6e-62 ycbP S Protein of unknown function (DUF2512)
KMCOHGGH_00274 2.5e-79 sleB 3.5.1.28 M Cell wall
KMCOHGGH_00275 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KMCOHGGH_00276 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KMCOHGGH_00277 4.7e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KMCOHGGH_00278 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KMCOHGGH_00279 1.1e-209 ycbU E Selenocysteine lyase
KMCOHGGH_00280 1.1e-238 lmrB EGP the major facilitator superfamily
KMCOHGGH_00281 1.2e-100 yxaF K Transcriptional regulator
KMCOHGGH_00282 9.9e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KMCOHGGH_00283 3.4e-112 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KMCOHGGH_00284 1.3e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
KMCOHGGH_00285 7.3e-172 yccK C Aldo keto reductase
KMCOHGGH_00286 5.6e-178 ycdA S Domain of unknown function (DUF5105)
KMCOHGGH_00287 1.3e-260 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KMCOHGGH_00288 3.9e-267 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KMCOHGGH_00289 2.4e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
KMCOHGGH_00290 4.6e-189 S response regulator aspartate phosphatase
KMCOHGGH_00291 7.3e-141 IQ Enoyl-(Acyl carrier protein) reductase
KMCOHGGH_00292 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KMCOHGGH_00293 6.7e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
KMCOHGGH_00294 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KMCOHGGH_00295 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KMCOHGGH_00296 3.3e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMCOHGGH_00297 2.8e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KMCOHGGH_00298 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
KMCOHGGH_00299 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
KMCOHGGH_00300 9.7e-138 terC P Protein of unknown function (DUF475)
KMCOHGGH_00301 0.0 yceG S Putative component of 'biosynthetic module'
KMCOHGGH_00302 6.7e-193 yceH P Belongs to the TelA family
KMCOHGGH_00303 8.1e-216 naiP P Uncharacterised MFS-type transporter YbfB
KMCOHGGH_00304 3.9e-229 proV 3.6.3.32 E glycine betaine
KMCOHGGH_00305 1.6e-138 opuAB P glycine betaine
KMCOHGGH_00306 3.1e-164 opuAC E glycine betaine
KMCOHGGH_00307 6.6e-212 amhX S amidohydrolase
KMCOHGGH_00308 5.3e-230 ycgA S Membrane
KMCOHGGH_00309 2.2e-82 ycgB
KMCOHGGH_00310 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
KMCOHGGH_00311 3.7e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KMCOHGGH_00312 8.1e-261 mdr EGP Major facilitator Superfamily
KMCOHGGH_00313 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
KMCOHGGH_00314 4.7e-114 ycgF E Lysine exporter protein LysE YggA
KMCOHGGH_00315 4.2e-149 yqcI S YqcI/YcgG family
KMCOHGGH_00316 9.8e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KMCOHGGH_00317 9.9e-114 ycgI S Domain of unknown function (DUF1989)
KMCOHGGH_00318 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KMCOHGGH_00320 5.6e-109 tmrB S AAA domain
KMCOHGGH_00321 6.2e-148 4.2.1.118 G Xylose isomerase-like TIM barrel
KMCOHGGH_00322 2.7e-233 G COG0477 Permeases of the major facilitator superfamily
KMCOHGGH_00323 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KMCOHGGH_00324 2.2e-54 L COG2963 Transposase and inactivated derivatives
KMCOHGGH_00325 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_00326 4.5e-185 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KMCOHGGH_00327 4e-147 ycgL S Predicted nucleotidyltransferase
KMCOHGGH_00328 2.3e-170 ycgM E Proline dehydrogenase
KMCOHGGH_00329 3.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KMCOHGGH_00330 9.7e-239 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMCOHGGH_00331 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
KMCOHGGH_00332 4.9e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KMCOHGGH_00333 1.9e-280 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KMCOHGGH_00334 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
KMCOHGGH_00335 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KMCOHGGH_00336 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMCOHGGH_00337 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KMCOHGGH_00338 2.9e-221 nasA P COG2223 Nitrate nitrite transporter
KMCOHGGH_00339 2.7e-227 yciC S GTPases (G3E family)
KMCOHGGH_00340 3.9e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KMCOHGGH_00341 1.2e-73 yckC S membrane
KMCOHGGH_00342 2.2e-51 S Protein of unknown function (DUF2680)
KMCOHGGH_00343 6.1e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KMCOHGGH_00344 5.5e-68 nin S Competence protein J (ComJ)
KMCOHGGH_00345 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
KMCOHGGH_00346 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KMCOHGGH_00347 2.8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KMCOHGGH_00348 6.3e-63 hxlR K transcriptional
KMCOHGGH_00349 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_00350 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_00351 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KMCOHGGH_00352 6.4e-139 srfAD Q thioesterase
KMCOHGGH_00353 1.6e-249 bamJ E Aminotransferase class I and II
KMCOHGGH_00354 3.8e-64 S YcxB-like protein
KMCOHGGH_00355 5e-168 ycxC EG EamA-like transporter family
KMCOHGGH_00356 2.4e-245 ycxD K GntR family transcriptional regulator
KMCOHGGH_00357 1e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KMCOHGGH_00358 4.1e-110 yczE S membrane
KMCOHGGH_00359 1.4e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KMCOHGGH_00360 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
KMCOHGGH_00361 5.1e-142 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KMCOHGGH_00362 1.6e-157 bsdA K LysR substrate binding domain
KMCOHGGH_00363 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KMCOHGGH_00364 2.4e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KMCOHGGH_00365 2e-38 bsdD 4.1.1.61 S response to toxic substance
KMCOHGGH_00366 1.3e-76 yclD
KMCOHGGH_00367 4.1e-270 dtpT E amino acid peptide transporter
KMCOHGGH_00368 3.2e-277 yclG M Pectate lyase superfamily protein
KMCOHGGH_00370 9.2e-295 gerKA EG Spore germination protein
KMCOHGGH_00371 1.6e-235 gerKC S spore germination
KMCOHGGH_00372 7.3e-195 gerKB F Spore germination protein
KMCOHGGH_00373 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMCOHGGH_00374 5.1e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMCOHGGH_00375 2.7e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
KMCOHGGH_00376 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
KMCOHGGH_00377 2.7e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
KMCOHGGH_00378 3.4e-219 yxeP 3.5.1.47 E hydrolase activity
KMCOHGGH_00379 6.4e-254 yxeQ S MmgE/PrpD family
KMCOHGGH_00380 3.3e-121 yclH P ABC transporter
KMCOHGGH_00381 6.2e-223 yclI V ABC transporter (permease) YclI
KMCOHGGH_00382 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_00383 4e-262 T PhoQ Sensor
KMCOHGGH_00384 1.9e-81 S aspartate phosphatase
KMCOHGGH_00386 2.1e-252 lysC 2.7.2.4 E Belongs to the aspartokinase family
KMCOHGGH_00387 2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMCOHGGH_00388 1e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMCOHGGH_00389 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KMCOHGGH_00390 9.3e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KMCOHGGH_00391 2.3e-249 ycnB EGP Major facilitator Superfamily
KMCOHGGH_00392 4.6e-152 ycnC K Transcriptional regulator
KMCOHGGH_00393 1.5e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
KMCOHGGH_00394 1e-44 ycnE S Monooxygenase
KMCOHGGH_00395 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KMCOHGGH_00396 5.3e-259 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMCOHGGH_00397 3.8e-219 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMCOHGGH_00398 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMCOHGGH_00399 3.6e-149 glcU U Glucose uptake
KMCOHGGH_00400 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMCOHGGH_00401 7.8e-98 ycnI S protein conserved in bacteria
KMCOHGGH_00402 6.1e-299 ycnJ P protein, homolog of Cu resistance protein CopC
KMCOHGGH_00403 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KMCOHGGH_00404 1.6e-55
KMCOHGGH_00405 5.8e-229 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KMCOHGGH_00406 3e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KMCOHGGH_00407 1.2e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KMCOHGGH_00408 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KMCOHGGH_00410 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KMCOHGGH_00411 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
KMCOHGGH_00412 4.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KMCOHGGH_00413 2.1e-151 ycsI S Belongs to the D-glutamate cyclase family
KMCOHGGH_00414 9.2e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KMCOHGGH_00415 1.4e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KMCOHGGH_00416 4e-131 kipR K Transcriptional regulator
KMCOHGGH_00417 2.1e-117 ycsK E anatomical structure formation involved in morphogenesis
KMCOHGGH_00419 3.3e-55 yczJ S biosynthesis
KMCOHGGH_00420 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KMCOHGGH_00421 1.3e-173 ydhF S Oxidoreductase
KMCOHGGH_00422 0.0 mtlR K transcriptional regulator, MtlR
KMCOHGGH_00423 6.5e-287 ydaB IQ acyl-CoA ligase
KMCOHGGH_00424 3.7e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMCOHGGH_00425 2.7e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KMCOHGGH_00426 2.7e-114 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KMCOHGGH_00427 1.4e-77 ydaG 1.4.3.5 S general stress protein
KMCOHGGH_00428 1.6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KMCOHGGH_00429 2.2e-54 L COG2963 Transposase and inactivated derivatives
KMCOHGGH_00430 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_00431 2.7e-48 ydzA EGP Major facilitator Superfamily
KMCOHGGH_00432 1.5e-74 lrpC K Transcriptional regulator
KMCOHGGH_00433 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMCOHGGH_00434 6.7e-201 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
KMCOHGGH_00435 1.1e-147 ydaK T Diguanylate cyclase, GGDEF domain
KMCOHGGH_00436 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
KMCOHGGH_00437 8.5e-232 ydaM M Glycosyl transferase family group 2
KMCOHGGH_00438 0.0 ydaN S Bacterial cellulose synthase subunit
KMCOHGGH_00439 0.0 ydaO E amino acid
KMCOHGGH_00440 8e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KMCOHGGH_00441 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KMCOHGGH_00442 8.2e-59 K acetyltransferase
KMCOHGGH_00444 1.3e-39 yqbQ 3.2.1.96 G NLP P60 protein
KMCOHGGH_00445 5.9e-34 xkdR S Protein of unknown function (DUF2577)
KMCOHGGH_00446 2.5e-108 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KMCOHGGH_00447 7.5e-16 xkdS S Protein of unknown function (DUF2634)
KMCOHGGH_00448 6.2e-21 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KMCOHGGH_00450 2.5e-79
KMCOHGGH_00451 5.6e-98
KMCOHGGH_00452 2.1e-39
KMCOHGGH_00453 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
KMCOHGGH_00455 6.5e-34 ydaT
KMCOHGGH_00456 2.4e-71 yvaD S Family of unknown function (DUF5360)
KMCOHGGH_00457 4.1e-54 yvaE P Small Multidrug Resistance protein
KMCOHGGH_00458 2.6e-141 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KMCOHGGH_00460 3.1e-62 ydbB G Cupin domain
KMCOHGGH_00461 2e-61 ydbC S Domain of unknown function (DUF4937
KMCOHGGH_00462 2.5e-155 ydbD P Catalase
KMCOHGGH_00463 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KMCOHGGH_00464 2.1e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KMCOHGGH_00465 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
KMCOHGGH_00466 5e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMCOHGGH_00467 3.2e-160 ydbI S AI-2E family transporter
KMCOHGGH_00468 9.5e-172 ydbJ V ABC transporter, ATP-binding protein
KMCOHGGH_00469 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KMCOHGGH_00470 2.1e-52 ydbL
KMCOHGGH_00471 5.4e-206 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KMCOHGGH_00472 1.5e-10 S Fur-regulated basic protein B
KMCOHGGH_00473 2.2e-08 S Fur-regulated basic protein A
KMCOHGGH_00474 8.1e-120 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMCOHGGH_00475 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KMCOHGGH_00476 5.1e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KMCOHGGH_00477 3.8e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KMCOHGGH_00478 1.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KMCOHGGH_00479 2.1e-82 ydbS S Bacterial PH domain
KMCOHGGH_00480 2.8e-263 ydbT S Membrane
KMCOHGGH_00481 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KMCOHGGH_00482 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KMCOHGGH_00483 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KMCOHGGH_00484 2.6e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMCOHGGH_00485 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KMCOHGGH_00486 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KMCOHGGH_00487 2.3e-145 rsbR T Positive regulator of sigma-B
KMCOHGGH_00488 1.8e-57 rsbS T antagonist
KMCOHGGH_00489 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KMCOHGGH_00490 4.6e-188 rsbU 3.1.3.3 KT phosphatase
KMCOHGGH_00491 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
KMCOHGGH_00492 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KMCOHGGH_00493 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMCOHGGH_00494 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KMCOHGGH_00495 0.0 yhgF K COG2183 Transcriptional accessory protein
KMCOHGGH_00496 1.7e-14
KMCOHGGH_00497 7.3e-58 ydcK S Belongs to the SprT family
KMCOHGGH_00505 1.1e-08
KMCOHGGH_00506 2.7e-29 S Doxx family
KMCOHGGH_00507 3.3e-78 K Transcriptional regulator
KMCOHGGH_00508 1.4e-97 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KMCOHGGH_00509 8.2e-96 ywrO 1.6.5.2 S Flavodoxin-like fold
KMCOHGGH_00510 8.8e-230 proP EGP Transporter
KMCOHGGH_00511 1.3e-48 ohrR K Transcriptional regulator
KMCOHGGH_00512 8e-74 S Domain of unknown function with cystatin-like fold (DUF4467)
KMCOHGGH_00513 1.3e-72 maoC I N-terminal half of MaoC dehydratase
KMCOHGGH_00514 6.6e-62 yyaQ S YjbR
KMCOHGGH_00515 3.1e-72 ywnA K Transcriptional regulator
KMCOHGGH_00516 5.3e-113 ywnB S NAD(P)H-binding
KMCOHGGH_00518 3.3e-90 K Bacterial regulatory proteins, tetR family
KMCOHGGH_00519 2.9e-110 C Enoyl-(Acyl carrier protein) reductase
KMCOHGGH_00520 2.9e-174 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KMCOHGGH_00521 3.4e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KMCOHGGH_00522 1.4e-30 cspL K Cold shock
KMCOHGGH_00523 1.2e-79 carD K Transcription factor
KMCOHGGH_00524 3.9e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KMCOHGGH_00525 5.4e-101 S Protein of unknown function (DUF2812)
KMCOHGGH_00526 1.4e-50 K Transcriptional regulator PadR-like family
KMCOHGGH_00527 3.8e-173 ybfA 3.4.15.5 K FR47-like protein
KMCOHGGH_00528 3.8e-235 ybfB G COG0477 Permeases of the major facilitator superfamily
KMCOHGGH_00529 2e-180 S Patatin-like phospholipase
KMCOHGGH_00530 1.1e-83 S DinB superfamily
KMCOHGGH_00531 4.1e-62 G Cupin domain
KMCOHGGH_00534 3e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
KMCOHGGH_00535 1.7e-75 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMCOHGGH_00536 1.2e-169 czcD P COG1230 Co Zn Cd efflux system component
KMCOHGGH_00537 1.3e-201 trkA P Oxidoreductase
KMCOHGGH_00539 1.5e-148 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
KMCOHGGH_00541 7.1e-200 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
KMCOHGGH_00542 5.5e-47 ydeH
KMCOHGGH_00543 2.4e-83 F nucleoside 2-deoxyribosyltransferase
KMCOHGGH_00544 6.6e-195 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KMCOHGGH_00545 1.2e-148 Q ubiE/COQ5 methyltransferase family
KMCOHGGH_00546 2.9e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KMCOHGGH_00547 1.4e-234 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KMCOHGGH_00548 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_00549 1.1e-40 L transposase activity
KMCOHGGH_00550 2.3e-165 S Sodium Bile acid symporter family
KMCOHGGH_00551 1.2e-202 adhA 1.1.1.1 C alcohol dehydrogenase
KMCOHGGH_00552 3.6e-67 yraB K helix_turn_helix, mercury resistance
KMCOHGGH_00553 1.3e-222 mleN_2 C antiporter
KMCOHGGH_00554 3.9e-262 K helix_turn_helix gluconate operon transcriptional repressor
KMCOHGGH_00555 6.7e-113 paiB K Transcriptional regulator
KMCOHGGH_00557 1.2e-179 ydeR EGP Major facilitator Superfamily
KMCOHGGH_00558 4.5e-103 ydeS K Transcriptional regulator
KMCOHGGH_00559 1.3e-157 ydeK EG -transporter
KMCOHGGH_00560 3.4e-266 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMCOHGGH_00561 4.3e-49 yraD M Spore coat protein
KMCOHGGH_00562 1.8e-24 yraE
KMCOHGGH_00563 7.2e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KMCOHGGH_00564 8.4e-63 yraF M Spore coat protein
KMCOHGGH_00565 4.5e-36 yraG
KMCOHGGH_00566 2.6e-220 ydfH 2.7.13.3 T Histidine kinase
KMCOHGGH_00567 4.3e-107 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMCOHGGH_00568 0.0 ydfJ S drug exporters of the RND superfamily
KMCOHGGH_00569 1.2e-133 puuD S Peptidase C26
KMCOHGGH_00570 9.4e-300 expZ S ABC transporter
KMCOHGGH_00571 1.3e-101 ynaD J Acetyltransferase (GNAT) domain
KMCOHGGH_00572 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
KMCOHGGH_00573 2.7e-197 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
KMCOHGGH_00574 8.8e-210 tcaB EGP Major facilitator Superfamily
KMCOHGGH_00575 3.7e-224 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KMCOHGGH_00576 5e-156 K Helix-turn-helix XRE-family like proteins
KMCOHGGH_00577 2.9e-123 ydhB S membrane transporter protein
KMCOHGGH_00578 2.2e-81 bltD 2.3.1.57 K FR47-like protein
KMCOHGGH_00579 2e-149 bltR K helix_turn_helix, mercury resistance
KMCOHGGH_00580 5.3e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KMCOHGGH_00581 2.7e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KMCOHGGH_00582 2e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
KMCOHGGH_00583 6.1e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KMCOHGGH_00584 1.3e-120 ydhC K FCD
KMCOHGGH_00585 3.7e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KMCOHGGH_00588 4.3e-266 pbpE V Beta-lactamase
KMCOHGGH_00590 2.5e-98 ydhK M Protein of unknown function (DUF1541)
KMCOHGGH_00591 1.2e-195 pbuE EGP Major facilitator Superfamily
KMCOHGGH_00592 1.3e-133 ydhQ K UTRA
KMCOHGGH_00593 2.6e-118 K FCD
KMCOHGGH_00594 1.7e-216 yeaN P COG2807 Cyanate permease
KMCOHGGH_00595 7.7e-49 sugE P Small Multidrug Resistance protein
KMCOHGGH_00596 2.3e-51 ykkC P Small Multidrug Resistance protein
KMCOHGGH_00597 5.3e-104 yvdT K Transcriptional regulator
KMCOHGGH_00598 9.3e-297 yveA E amino acid
KMCOHGGH_00599 3.2e-166 ydhU P Catalase
KMCOHGGH_00600 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
KMCOHGGH_00601 4.7e-185 yhfP 1.1.1.1 C Quinone oxidoreductase
KMCOHGGH_00602 2.2e-252 iolT EGP Major facilitator Superfamily
KMCOHGGH_00605 3.4e-39 S COG NOG14552 non supervised orthologous group
KMCOHGGH_00606 7.8e-08
KMCOHGGH_00608 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KMCOHGGH_00609 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KMCOHGGH_00610 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KMCOHGGH_00611 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KMCOHGGH_00612 3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KMCOHGGH_00613 0.0 ydiF S ABC transporter
KMCOHGGH_00614 1e-87 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KMCOHGGH_00615 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KMCOHGGH_00616 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KMCOHGGH_00617 2.1e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KMCOHGGH_00618 1.5e-26 ydiK S Domain of unknown function (DUF4305)
KMCOHGGH_00619 2.5e-127 ydiL S CAAX protease self-immunity
KMCOHGGH_00620 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KMCOHGGH_00621 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KMCOHGGH_00622 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
KMCOHGGH_00625 9.5e-65
KMCOHGGH_00626 0.0 K NB-ARC domain
KMCOHGGH_00627 4.3e-60 K NB-ARC domain
KMCOHGGH_00628 6.5e-201 gutB 1.1.1.14 E Dehydrogenase
KMCOHGGH_00629 2e-250 gutA G MFS/sugar transport protein
KMCOHGGH_00630 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KMCOHGGH_00631 2.8e-30 yjdJ S Domain of unknown function (DUF4306)
KMCOHGGH_00632 3e-114 pspA KT Phage shock protein A
KMCOHGGH_00633 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KMCOHGGH_00634 1.4e-120 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KMCOHGGH_00635 3.1e-144 ydjI S virion core protein (lumpy skin disease virus)
KMCOHGGH_00636 0.0 yrhL I Acyltransferase family
KMCOHGGH_00637 5.4e-145 rsiV S Protein of unknown function (DUF3298)
KMCOHGGH_00638 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KMCOHGGH_00639 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KMCOHGGH_00640 4.2e-62 ydjM M Lytic transglycolase
KMCOHGGH_00641 9.4e-136 ydjN U Involved in the tonB-independent uptake of proteins
KMCOHGGH_00643 7.2e-35 ydjO S Cold-inducible protein YdjO
KMCOHGGH_00644 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KMCOHGGH_00645 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KMCOHGGH_00646 2.4e-153 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMCOHGGH_00647 4.6e-177 yeaC S COG0714 MoxR-like ATPases
KMCOHGGH_00648 1.3e-213 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KMCOHGGH_00649 0.0 yebA E COG1305 Transglutaminase-like enzymes
KMCOHGGH_00650 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KMCOHGGH_00651 2.2e-126 K Acetyltransferase (GNAT) domain
KMCOHGGH_00652 7.8e-94 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KMCOHGGH_00653 7.6e-245 S Domain of unknown function (DUF4179)
KMCOHGGH_00654 6.2e-209 pbuG S permease
KMCOHGGH_00655 8.7e-126 yebC M Membrane
KMCOHGGH_00657 7.5e-92 yebE S UPF0316 protein
KMCOHGGH_00658 5.5e-29 yebG S NETI protein
KMCOHGGH_00659 3.7e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KMCOHGGH_00660 2.6e-222 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KMCOHGGH_00661 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KMCOHGGH_00662 6.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KMCOHGGH_00663 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMCOHGGH_00664 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMCOHGGH_00665 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMCOHGGH_00666 2.1e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KMCOHGGH_00667 5.1e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KMCOHGGH_00668 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KMCOHGGH_00669 4.6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KMCOHGGH_00670 4.8e-235 purD 6.3.4.13 F Belongs to the GARS family
KMCOHGGH_00671 4.9e-24 S Protein of unknown function (DUF2892)
KMCOHGGH_00672 0.0 yerA 3.5.4.2 F adenine deaminase
KMCOHGGH_00673 1.2e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
KMCOHGGH_00674 2.4e-50 yerC S protein conserved in bacteria
KMCOHGGH_00675 6.7e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KMCOHGGH_00676 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KMCOHGGH_00677 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KMCOHGGH_00678 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KMCOHGGH_00679 1.4e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
KMCOHGGH_00680 3.8e-195 yerI S homoserine kinase type II (protein kinase fold)
KMCOHGGH_00681 1.3e-120 sapB S MgtC SapB transporter
KMCOHGGH_00682 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMCOHGGH_00683 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMCOHGGH_00684 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KMCOHGGH_00685 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMCOHGGH_00686 7.6e-152 yerO K Transcriptional regulator
KMCOHGGH_00687 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KMCOHGGH_00688 2.1e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KMCOHGGH_00689 9.2e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMCOHGGH_00690 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
KMCOHGGH_00691 2.4e-99 3.1.21.3 V PFAM restriction modification system DNA specificity domain
KMCOHGGH_00692 0.0 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
KMCOHGGH_00693 1.5e-36 S Protein of unknown function (DUF1643)
KMCOHGGH_00694 2.5e-24 S Protein of unknown function, DUF600
KMCOHGGH_00695 2.1e-26 S Colicin immunity protein / pyocin immunity protein
KMCOHGGH_00696 1.1e-54 S Protein of unknown function, DUF600
KMCOHGGH_00697 5.9e-77 S Protein of unknown function, DUF600
KMCOHGGH_00698 2.7e-89 yobL L nucleic acid phosphodiester bond hydrolysis
KMCOHGGH_00699 3.9e-42 S Immunity protein 22
KMCOHGGH_00700 9.7e-240 yobL S Bacterial EndoU nuclease
KMCOHGGH_00701 9.4e-127 yeeN K transcriptional regulatory protein
KMCOHGGH_00703 2.4e-108 aadK G Streptomycin adenylyltransferase
KMCOHGGH_00704 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
KMCOHGGH_00705 3.3e-45 cotJB S CotJB protein
KMCOHGGH_00706 8.9e-104 cotJC P Spore Coat
KMCOHGGH_00707 5.2e-98 yesJ K Acetyltransferase (GNAT) family
KMCOHGGH_00709 9.6e-121 yetF S membrane
KMCOHGGH_00710 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KMCOHGGH_00711 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMCOHGGH_00712 3.4e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMCOHGGH_00713 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
KMCOHGGH_00714 1.8e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
KMCOHGGH_00715 1.1e-105 yetJ S Belongs to the BI1 family
KMCOHGGH_00716 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
KMCOHGGH_00717 2e-208 yetM CH FAD binding domain
KMCOHGGH_00718 2.6e-197 yetN S Protein of unknown function (DUF3900)
KMCOHGGH_00719 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KMCOHGGH_00720 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KMCOHGGH_00721 2.3e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
KMCOHGGH_00722 9.2e-172 yfnG 4.2.1.45 M dehydratase
KMCOHGGH_00723 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
KMCOHGGH_00724 3.9e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KMCOHGGH_00725 5.6e-188 yfnD M Nucleotide-diphospho-sugar transferase
KMCOHGGH_00726 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
KMCOHGGH_00727 7.8e-247 yfnA E amino acid
KMCOHGGH_00728 2e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMCOHGGH_00729 9.8e-115 yfmS NT chemotaxis protein
KMCOHGGH_00730 5.2e-167 IQ Enoyl-(Acyl carrier protein) reductase
KMCOHGGH_00731 6.5e-209 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KMCOHGGH_00732 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KMCOHGGH_00733 1.8e-69 yfmP K transcriptional
KMCOHGGH_00734 2.1e-208 yfmO EGP Major facilitator Superfamily
KMCOHGGH_00735 4.2e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KMCOHGGH_00736 1.1e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KMCOHGGH_00737 3.7e-65 yfmK 2.3.1.128 K acetyltransferase
KMCOHGGH_00738 3.2e-189 yfmJ S N-terminal domain of oxidoreductase
KMCOHGGH_00739 4.9e-24 S Protein of unknown function (DUF3212)
KMCOHGGH_00740 1.3e-57 yflT S Heat induced stress protein YflT
KMCOHGGH_00741 1.9e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KMCOHGGH_00742 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
KMCOHGGH_00743 1e-34 Q PFAM Collagen triple helix
KMCOHGGH_00744 2.5e-130 Q calcium- and calmodulin-responsive adenylate cyclase activity
KMCOHGGH_00745 1.8e-22 M1-820 Q Collagen triple helix repeat (20 copies)
KMCOHGGH_00746 8.9e-24 M1-820 Q Collagen triple helix repeat (20 copies)
KMCOHGGH_00747 5.7e-273 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KMCOHGGH_00748 4.7e-120 citT T response regulator
KMCOHGGH_00749 9.2e-178 yflP S Tripartite tricarboxylate transporter family receptor
KMCOHGGH_00750 3.8e-227 citM C Citrate transporter
KMCOHGGH_00751 8.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KMCOHGGH_00752 5.5e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KMCOHGGH_00753 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KMCOHGGH_00754 4.9e-122 yflK S protein conserved in bacteria
KMCOHGGH_00755 1.5e-14 yflJ S Protein of unknown function (DUF2639)
KMCOHGGH_00756 7e-19 yflI
KMCOHGGH_00757 3.1e-50 yflH S Protein of unknown function (DUF3243)
KMCOHGGH_00758 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
KMCOHGGH_00759 1.5e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KMCOHGGH_00760 2.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
KMCOHGGH_00761 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KMCOHGGH_00762 3.8e-63 yhdN S Domain of unknown function (DUF1992)
KMCOHGGH_00763 9.8e-79 cotP O Belongs to the small heat shock protein (HSP20) family
KMCOHGGH_00764 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
KMCOHGGH_00765 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
KMCOHGGH_00766 3.6e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMCOHGGH_00767 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KMCOHGGH_00768 2.6e-129 treR K transcriptional
KMCOHGGH_00769 1.2e-123 yfkO C nitroreductase
KMCOHGGH_00770 4.2e-125 yibF S YibE/F-like protein
KMCOHGGH_00771 4.1e-201 yibE S YibE/F-like protein
KMCOHGGH_00773 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
KMCOHGGH_00774 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
KMCOHGGH_00775 4e-187 K helix_turn _helix lactose operon repressor
KMCOHGGH_00776 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KMCOHGGH_00777 4.5e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KMCOHGGH_00778 1.5e-193 ydiM EGP Major facilitator Superfamily
KMCOHGGH_00779 2.7e-29 yfkK S Belongs to the UPF0435 family
KMCOHGGH_00780 3.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMCOHGGH_00781 1.3e-51 yfkI S gas vesicle protein
KMCOHGGH_00782 6.8e-145 yihY S Belongs to the UPF0761 family
KMCOHGGH_00783 2.5e-07
KMCOHGGH_00784 2.9e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KMCOHGGH_00785 1.3e-185 cax P COG0387 Ca2 H antiporter
KMCOHGGH_00786 1.9e-144 yfkD S YfkD-like protein
KMCOHGGH_00787 3.3e-147 yfkC M Mechanosensitive ion channel
KMCOHGGH_00788 1.1e-219 yfkA S YfkB-like domain
KMCOHGGH_00789 4.9e-27 yfjT
KMCOHGGH_00790 5.8e-154 pdaA G deacetylase
KMCOHGGH_00791 1.2e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KMCOHGGH_00792 7.1e-33
KMCOHGGH_00793 3.8e-184 corA P Mediates influx of magnesium ions
KMCOHGGH_00794 9.8e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KMCOHGGH_00795 5.6e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMCOHGGH_00796 1.7e-50 S YfzA-like protein
KMCOHGGH_00797 2.7e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KMCOHGGH_00798 3.3e-94 yfjM S Psort location Cytoplasmic, score
KMCOHGGH_00799 2.9e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMCOHGGH_00800 2.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMCOHGGH_00801 5.2e-215 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMCOHGGH_00802 5.4e-256 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMCOHGGH_00803 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KMCOHGGH_00804 4.2e-15 sspH S Belongs to the SspH family
KMCOHGGH_00805 7.6e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KMCOHGGH_00806 1.7e-139 glvR F Helix-turn-helix domain, rpiR family
KMCOHGGH_00807 2.4e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMCOHGGH_00808 0.0 yfiB3 V ABC transporter
KMCOHGGH_00809 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KMCOHGGH_00810 7e-63 mhqP S DoxX
KMCOHGGH_00811 7.7e-160 yfiE 1.13.11.2 S glyoxalase
KMCOHGGH_00812 1.3e-168 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KMCOHGGH_00813 1.5e-95 padR K transcriptional
KMCOHGGH_00814 1.9e-112 1.6.5.2 S NADPH-dependent FMN reductase
KMCOHGGH_00815 8.2e-183 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KMCOHGGH_00816 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
KMCOHGGH_00817 1.5e-45 yrdF K ribonuclease inhibitor
KMCOHGGH_00818 4.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
KMCOHGGH_00819 1.1e-289 yfiU EGP Major facilitator Superfamily
KMCOHGGH_00820 1.2e-82 yfiV K transcriptional
KMCOHGGH_00821 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KMCOHGGH_00822 5.1e-167 yfhB 5.3.3.17 S PhzF family
KMCOHGGH_00823 3.3e-106 yfhC C nitroreductase
KMCOHGGH_00824 8e-25 yfhD S YfhD-like protein
KMCOHGGH_00826 2.2e-165 yfhF S nucleoside-diphosphate sugar epimerase
KMCOHGGH_00827 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
KMCOHGGH_00828 8.8e-53 yfhH S Protein of unknown function (DUF1811)
KMCOHGGH_00829 1.5e-206 yfhI EGP Major facilitator Superfamily
KMCOHGGH_00831 3.4e-166 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KMCOHGGH_00832 2.2e-44 yfhJ S WVELL protein
KMCOHGGH_00833 1.7e-93 batE T Bacterial SH3 domain homologues
KMCOHGGH_00834 2.6e-34 yfhL S SdpI/YhfL protein family
KMCOHGGH_00835 1.7e-170 yfhM S Alpha/beta hydrolase family
KMCOHGGH_00836 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KMCOHGGH_00837 0.0 yfhO S Bacterial membrane protein YfhO
KMCOHGGH_00838 2.3e-184 yfhP S membrane-bound metal-dependent
KMCOHGGH_00839 4.7e-210 mutY L A G-specific
KMCOHGGH_00840 8.2e-37 yfhS
KMCOHGGH_00841 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMCOHGGH_00843 1.5e-37 ygaB S YgaB-like protein
KMCOHGGH_00844 2.2e-104 ygaC J Belongs to the UPF0374 family
KMCOHGGH_00845 2.7e-305 ygaD V ABC transporter
KMCOHGGH_00846 2.1e-178 ygaE S Membrane
KMCOHGGH_00847 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KMCOHGGH_00848 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
KMCOHGGH_00849 1.8e-80 perR P Belongs to the Fur family
KMCOHGGH_00850 1.5e-56 ygzB S UPF0295 protein
KMCOHGGH_00851 3.7e-165 ygxA S Nucleotidyltransferase-like
KMCOHGGH_00852 3.4e-39 S COG NOG14552 non supervised orthologous group
KMCOHGGH_00857 7.8e-08
KMCOHGGH_00865 1.6e-08
KMCOHGGH_00869 1.3e-277 C Na+/H+ antiporter family
KMCOHGGH_00870 3.6e-93 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KMCOHGGH_00871 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KMCOHGGH_00872 1.1e-264 ygaK C Berberine and berberine like
KMCOHGGH_00874 9.2e-229 oppA5 E PFAM extracellular solute-binding protein family 5
KMCOHGGH_00875 2.4e-138 appB P Binding-protein-dependent transport system inner membrane component
KMCOHGGH_00876 2.4e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMCOHGGH_00877 1.3e-134 oppD3 P Belongs to the ABC transporter superfamily
KMCOHGGH_00878 1.6e-134 oppF3 E Belongs to the ABC transporter superfamily
KMCOHGGH_00879 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KMCOHGGH_00880 3.9e-161 S Amidohydrolase
KMCOHGGH_00881 6.1e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KMCOHGGH_00882 2.7e-180 ssuA M Sulfonate ABC transporter
KMCOHGGH_00883 1.5e-144 ssuC P ABC transporter (permease)
KMCOHGGH_00884 1.4e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KMCOHGGH_00885 7.8e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMCOHGGH_00886 6.6e-81 ygaO
KMCOHGGH_00887 4.8e-23 K Transcriptional regulator
KMCOHGGH_00889 1.6e-111 yhzB S B3/4 domain
KMCOHGGH_00890 1.4e-225 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KMCOHGGH_00891 2.4e-175 yhbB S Putative amidase domain
KMCOHGGH_00892 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KMCOHGGH_00893 3.5e-109 yhbD K Protein of unknown function (DUF4004)
KMCOHGGH_00894 2.8e-62 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KMCOHGGH_00895 2.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KMCOHGGH_00897 0.0 prkA T Ser protein kinase
KMCOHGGH_00898 2.7e-216 yhbH S Belongs to the UPF0229 family
KMCOHGGH_00899 4.6e-74 yhbI K DNA-binding transcription factor activity
KMCOHGGH_00900 1.8e-97 yhbJ V COG1566 Multidrug resistance efflux pump
KMCOHGGH_00901 8.4e-285 yhcA EGP Major facilitator Superfamily
KMCOHGGH_00902 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
KMCOHGGH_00903 3.8e-55 yhcC
KMCOHGGH_00904 7.3e-53
KMCOHGGH_00905 7.3e-62 yhcF K Transcriptional regulator
KMCOHGGH_00906 1.1e-124 yhcG V ABC transporter, ATP-binding protein
KMCOHGGH_00907 5.3e-167 yhcH V ABC transporter, ATP-binding protein
KMCOHGGH_00908 7.4e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KMCOHGGH_00909 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
KMCOHGGH_00910 5.9e-149 metQ M Belongs to the nlpA lipoprotein family
KMCOHGGH_00911 8.4e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KMCOHGGH_00912 1.9e-221 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMCOHGGH_00913 6.5e-55 yhcM
KMCOHGGH_00914 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMCOHGGH_00915 1.8e-159 yhcP
KMCOHGGH_00916 2.9e-114 yhcQ M Spore coat protein
KMCOHGGH_00917 2e-255 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
KMCOHGGH_00918 5.6e-57 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
KMCOHGGH_00919 8.1e-108 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KMCOHGGH_00920 1.1e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KMCOHGGH_00921 1.3e-69 yhcU S Family of unknown function (DUF5365)
KMCOHGGH_00922 2.6e-68 yhcV S COG0517 FOG CBS domain
KMCOHGGH_00923 5.5e-124 yhcW 5.4.2.6 S hydrolase
KMCOHGGH_00924 1.1e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KMCOHGGH_00925 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_00926 2.2e-54 L COG2963 Transposase and inactivated derivatives
KMCOHGGH_00927 1.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMCOHGGH_00928 1.5e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KMCOHGGH_00929 4e-145 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KMCOHGGH_00930 7e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KMCOHGGH_00931 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KMCOHGGH_00932 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KMCOHGGH_00933 1.8e-204 yhcY 2.7.13.3 T Histidine kinase
KMCOHGGH_00934 3.8e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMCOHGGH_00935 8.8e-90 azr 1.7.1.6 S NADPH-dependent FMN reductase
KMCOHGGH_00936 2.5e-39 yhdB S YhdB-like protein
KMCOHGGH_00937 3.1e-53 yhdC S Protein of unknown function (DUF3889)
KMCOHGGH_00938 2e-216 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KMCOHGGH_00939 1.9e-74 nsrR K Transcriptional regulator
KMCOHGGH_00940 1.7e-255 ygxB M Conserved TM helix
KMCOHGGH_00941 1.2e-271 ycgB S Stage V sporulation protein R
KMCOHGGH_00942 4.9e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KMCOHGGH_00943 4.8e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KMCOHGGH_00944 9e-164 citR K Transcriptional regulator
KMCOHGGH_00945 1.8e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
KMCOHGGH_00946 5.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMCOHGGH_00947 9.1e-251 yhdG E amino acid
KMCOHGGH_00948 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KMCOHGGH_00949 8.1e-45 yhdK S Sigma-M inhibitor protein
KMCOHGGH_00950 4.3e-200 yhdL S Sigma factor regulator N-terminal
KMCOHGGH_00951 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KMCOHGGH_00952 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KMCOHGGH_00953 1.6e-241 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KMCOHGGH_00954 4.3e-71 cueR K transcriptional
KMCOHGGH_00955 7.7e-227 yhdR 2.6.1.1 E Aminotransferase
KMCOHGGH_00956 5.1e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KMCOHGGH_00957 3.2e-256 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KMCOHGGH_00958 2.5e-51 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMCOHGGH_00959 2e-62 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMCOHGGH_00960 2e-129 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KMCOHGGH_00962 1.6e-205 yhdY M Mechanosensitive ion channel
KMCOHGGH_00963 6.5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KMCOHGGH_00964 1.2e-157 yheN G deacetylase
KMCOHGGH_00965 4.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KMCOHGGH_00966 1.3e-87 pksA K Transcriptional regulator
KMCOHGGH_00967 1.2e-94 ymcC S Membrane
KMCOHGGH_00968 2.1e-85 T universal stress protein
KMCOHGGH_00970 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KMCOHGGH_00971 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KMCOHGGH_00972 1.6e-111 yheG GM NAD(P)H-binding
KMCOHGGH_00974 2.9e-28 sspB S spore protein
KMCOHGGH_00975 4.9e-36 yheE S Family of unknown function (DUF5342)
KMCOHGGH_00976 1.6e-260 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KMCOHGGH_00977 4.8e-215 yheC HJ YheC/D like ATP-grasp
KMCOHGGH_00978 5.5e-206 yheB S Belongs to the UPF0754 family
KMCOHGGH_00979 1.5e-53 yheA S Belongs to the UPF0342 family
KMCOHGGH_00980 3e-204 yhaZ L DNA alkylation repair enzyme
KMCOHGGH_00981 3.3e-158 yhaX S haloacid dehalogenase-like hydrolase
KMCOHGGH_00982 9.3e-294 hemZ H coproporphyrinogen III oxidase
KMCOHGGH_00983 9.2e-250 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
KMCOHGGH_00984 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
KMCOHGGH_00985 1.7e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KMCOHGGH_00987 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
KMCOHGGH_00988 2.8e-14 S YhzD-like protein
KMCOHGGH_00989 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
KMCOHGGH_00990 8e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KMCOHGGH_00991 1.4e-236 yhaO L DNA repair exonuclease
KMCOHGGH_00992 0.0 yhaN L AAA domain
KMCOHGGH_00993 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KMCOHGGH_00994 1.1e-31 yhaL S Sporulation protein YhaL
KMCOHGGH_00995 3.3e-123 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KMCOHGGH_00996 7e-95 yhaK S Putative zincin peptidase
KMCOHGGH_00997 9.9e-55 yhaI S Protein of unknown function (DUF1878)
KMCOHGGH_00998 8.6e-113 hpr K Negative regulator of protease production and sporulation
KMCOHGGH_00999 6.2e-39 yhaH S YtxH-like protein
KMCOHGGH_01000 2e-17
KMCOHGGH_01001 3.8e-77 trpP S Tryptophan transporter TrpP
KMCOHGGH_01002 2.1e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KMCOHGGH_01003 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KMCOHGGH_01004 1.1e-135 ecsA V transporter (ATP-binding protein)
KMCOHGGH_01005 8.5e-221 ecsB U ABC transporter
KMCOHGGH_01006 9.5e-124 ecsC S EcsC protein family
KMCOHGGH_01007 6.1e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KMCOHGGH_01008 1.4e-243 yhfA C membrane
KMCOHGGH_01009 6e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KMCOHGGH_01010 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KMCOHGGH_01011 1.9e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KMCOHGGH_01012 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KMCOHGGH_01013 1.6e-274 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KMCOHGGH_01014 4.6e-100 yhgD K Transcriptional regulator
KMCOHGGH_01015 3.2e-277 yhgE S YhgE Pip N-terminal domain protein
KMCOHGGH_01016 7.4e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMCOHGGH_01018 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KMCOHGGH_01019 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMCOHGGH_01020 1.5e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KMCOHGGH_01021 3.5e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
KMCOHGGH_01022 2.6e-112 yhfK GM NmrA-like family
KMCOHGGH_01023 6.4e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KMCOHGGH_01024 1.9e-65 yhfM
KMCOHGGH_01025 9.6e-236 yhfN 3.4.24.84 O Peptidase M48
KMCOHGGH_01026 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KMCOHGGH_01027 1.1e-153 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KMCOHGGH_01028 1.7e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KMCOHGGH_01029 2.1e-202 vraB 2.3.1.9 I Belongs to the thiolase family
KMCOHGGH_01030 5e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KMCOHGGH_01031 6e-89 bioY S BioY family
KMCOHGGH_01032 9.1e-197 hemAT NT chemotaxis protein
KMCOHGGH_01033 1.8e-297 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KMCOHGGH_01034 1.4e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMCOHGGH_01035 1.4e-31 yhzC S IDEAL
KMCOHGGH_01036 1.9e-109 comK K Competence transcription factor
KMCOHGGH_01037 5.1e-68 frataxin S Domain of unknown function (DU1801)
KMCOHGGH_01038 2e-64 frataxin S Domain of unknown function (DU1801)
KMCOHGGH_01039 8.3e-168 els S Acetyltransferase, GNAT family
KMCOHGGH_01040 5.4e-127 yrpD S Domain of unknown function, YrpD
KMCOHGGH_01041 1.6e-42 yhjA S Excalibur calcium-binding domain
KMCOHGGH_01042 3.3e-47 S Belongs to the UPF0145 family
KMCOHGGH_01043 2.9e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMCOHGGH_01044 1.4e-27 yhjC S Protein of unknown function (DUF3311)
KMCOHGGH_01045 1.1e-59 yhjD
KMCOHGGH_01046 1.4e-110 yhjE S SNARE associated Golgi protein
KMCOHGGH_01047 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KMCOHGGH_01048 1.1e-275 yhjG CH FAD binding domain
KMCOHGGH_01049 1.7e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
KMCOHGGH_01050 4.8e-181 abrB S membrane
KMCOHGGH_01051 2.5e-209 blt EGP Major facilitator Superfamily
KMCOHGGH_01052 3.8e-108 K QacR-like protein, C-terminal region
KMCOHGGH_01053 1.4e-92 yhjR S Rubrerythrin
KMCOHGGH_01054 7.9e-126 ydfS S Protein of unknown function (DUF421)
KMCOHGGH_01055 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KMCOHGGH_01056 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KMCOHGGH_01057 3e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KMCOHGGH_01058 0.0 sbcC L COG0419 ATPase involved in DNA repair
KMCOHGGH_01059 2.9e-50 yisB V COG1403 Restriction endonuclease
KMCOHGGH_01060 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
KMCOHGGH_01061 8.1e-64 gerPE S Spore germination protein GerPE
KMCOHGGH_01062 3.1e-23 gerPD S Spore germination protein
KMCOHGGH_01063 4.1e-62 gerPC S Spore germination protein
KMCOHGGH_01064 6.2e-35 gerPB S cell differentiation
KMCOHGGH_01065 8.4e-34 gerPA S Spore germination protein
KMCOHGGH_01066 5e-07 yisI S Spo0E like sporulation regulatory protein
KMCOHGGH_01067 1.2e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KMCOHGGH_01068 1.1e-59 yisL S UPF0344 protein
KMCOHGGH_01069 1.5e-97 yisN S Protein of unknown function (DUF2777)
KMCOHGGH_01070 0.0 asnO 6.3.5.4 E Asparagine synthase
KMCOHGGH_01071 4.3e-135 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KMCOHGGH_01072 1.3e-244 yisQ V Mate efflux family protein
KMCOHGGH_01073 5e-159 yisR K Transcriptional regulator
KMCOHGGH_01074 6.3e-90 yisT S DinB family
KMCOHGGH_01075 1.3e-71 mcbG S Pentapeptide repeats (9 copies)
KMCOHGGH_01076 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
KMCOHGGH_01077 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KMCOHGGH_01078 6.6e-55 yajQ S Belongs to the UPF0234 family
KMCOHGGH_01079 1.8e-161 cvfB S protein conserved in bacteria
KMCOHGGH_01080 2.5e-175 yufN S ABC transporter substrate-binding protein PnrA-like
KMCOHGGH_01081 1e-232 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
KMCOHGGH_01082 5.3e-242 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KMCOHGGH_01084 1.9e-158 yitS S protein conserved in bacteria
KMCOHGGH_01085 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KMCOHGGH_01086 2.9e-81 ipi S Intracellular proteinase inhibitor
KMCOHGGH_01087 4.4e-26 S Protein of unknown function (DUF3813)
KMCOHGGH_01088 3.5e-07
KMCOHGGH_01089 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KMCOHGGH_01090 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KMCOHGGH_01091 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
KMCOHGGH_01092 1.4e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KMCOHGGH_01093 3.9e-273 yitY C D-arabinono-1,4-lactone oxidase
KMCOHGGH_01094 4.1e-90 norB G Major Facilitator Superfamily
KMCOHGGH_01095 4.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KMCOHGGH_01096 7.2e-228 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KMCOHGGH_01097 1.5e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
KMCOHGGH_01098 3.1e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KMCOHGGH_01099 8.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KMCOHGGH_01100 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KMCOHGGH_01101 2.1e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KMCOHGGH_01102 1.2e-27 yjzC S YjzC-like protein
KMCOHGGH_01103 1.5e-23 yjzD S Protein of unknown function (DUF2929)
KMCOHGGH_01104 9.9e-140 yjaU I carboxylic ester hydrolase activity
KMCOHGGH_01105 1.5e-106 yjaV
KMCOHGGH_01106 1.9e-166 med S Transcriptional activator protein med
KMCOHGGH_01107 1.9e-26 comZ S ComZ
KMCOHGGH_01108 5.9e-32 yjzB
KMCOHGGH_01109 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMCOHGGH_01110 5.8e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KMCOHGGH_01111 4.7e-148 yjaZ O Zn-dependent protease
KMCOHGGH_01112 6.3e-182 appD P Belongs to the ABC transporter superfamily
KMCOHGGH_01113 5.9e-188 appF E Belongs to the ABC transporter superfamily
KMCOHGGH_01114 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KMCOHGGH_01115 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMCOHGGH_01116 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMCOHGGH_01117 5.5e-146 yjbA S Belongs to the UPF0736 family
KMCOHGGH_01118 3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KMCOHGGH_01119 0.0 oppA E ABC transporter substrate-binding protein
KMCOHGGH_01120 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMCOHGGH_01121 6.4e-15 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMCOHGGH_01122 3.6e-109 yjbE P Integral membrane protein TerC family
KMCOHGGH_01123 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KMCOHGGH_01124 1.1e-220 yjbF S Competence protein
KMCOHGGH_01125 0.0 pepF E oligoendopeptidase F
KMCOHGGH_01126 5.8e-19
KMCOHGGH_01127 8.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KMCOHGGH_01128 4.8e-72 yjbI S Bacterial-like globin
KMCOHGGH_01129 4.5e-118 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KMCOHGGH_01130 4.6e-100 yjbK S protein conserved in bacteria
KMCOHGGH_01131 3.5e-61 yjbL S Belongs to the UPF0738 family
KMCOHGGH_01132 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
KMCOHGGH_01133 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KMCOHGGH_01134 2e-163 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KMCOHGGH_01135 1.4e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KMCOHGGH_01136 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KMCOHGGH_01137 2.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KMCOHGGH_01138 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KMCOHGGH_01139 1.3e-212 thiO 1.4.3.19 E Glycine oxidase
KMCOHGGH_01140 1.4e-30 thiS H Thiamine biosynthesis
KMCOHGGH_01141 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KMCOHGGH_01142 4.6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KMCOHGGH_01143 4.9e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KMCOHGGH_01144 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KMCOHGGH_01145 3e-89 yjbX S Spore coat protein
KMCOHGGH_01146 6.9e-80 cotZ S Spore coat protein
KMCOHGGH_01147 8.1e-90 cotY S Spore coat protein Z
KMCOHGGH_01148 4.4e-75 cotX S Spore Coat Protein X and V domain
KMCOHGGH_01149 1.1e-23 cotW
KMCOHGGH_01150 4.2e-57 cotV S Spore Coat Protein X and V domain
KMCOHGGH_01151 2.5e-56 yjcA S Protein of unknown function (DUF1360)
KMCOHGGH_01155 3.8e-38 spoVIF S Stage VI sporulation protein F
KMCOHGGH_01156 0.0 yjcD 3.6.4.12 L DNA helicase
KMCOHGGH_01157 2.1e-36
KMCOHGGH_01158 1.5e-138 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
KMCOHGGH_01159 4e-125 S ABC-2 type transporter
KMCOHGGH_01160 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
KMCOHGGH_01161 9.4e-36 K SpoVT / AbrB like domain
KMCOHGGH_01163 8.5e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMCOHGGH_01164 1.2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KMCOHGGH_01165 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
KMCOHGGH_01166 1.3e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KMCOHGGH_01167 2.6e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KMCOHGGH_01170 8.2e-57
KMCOHGGH_01171 0.0 yobL S Bacterial EndoU nuclease
KMCOHGGH_01174 3.5e-59 E Glyoxalase-like domain
KMCOHGGH_01176 8.5e-165 bla 3.5.2.6 V beta-lactamase
KMCOHGGH_01177 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
KMCOHGGH_01178 1.2e-250 yfjF EGP Belongs to the major facilitator superfamily
KMCOHGGH_01179 1.4e-81 napB K helix_turn_helix multiple antibiotic resistance protein
KMCOHGGH_01180 5.4e-222 ganA 3.2.1.89 G arabinogalactan
KMCOHGGH_01181 4.5e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KMCOHGGH_01182 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KMCOHGGH_01183 4.9e-218 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KMCOHGGH_01184 2.4e-311 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMCOHGGH_01185 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
KMCOHGGH_01186 4e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
KMCOHGGH_01187 5.1e-139 lacR K COG1349 Transcriptional regulators of sugar metabolism
KMCOHGGH_01188 1.3e-125 5.4.2.6 S Haloacid dehalogenase-like hydrolase
KMCOHGGH_01189 2.6e-34
KMCOHGGH_01190 2.2e-51 K helix_turn_helix multiple antibiotic resistance protein
KMCOHGGH_01191 8.1e-106 yhiD S MgtC SapB transporter
KMCOHGGH_01193 8.3e-21 yjfB S Putative motility protein
KMCOHGGH_01194 2.9e-69 T PhoQ Sensor
KMCOHGGH_01195 1.4e-101 yjgB S Domain of unknown function (DUF4309)
KMCOHGGH_01196 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KMCOHGGH_01197 1.3e-91 yjgD S Protein of unknown function (DUF1641)
KMCOHGGH_01198 1.6e-227 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KMCOHGGH_01199 1.2e-222 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KMCOHGGH_01200 6.8e-29
KMCOHGGH_01201 2.8e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KMCOHGGH_01202 3e-123 ybbM S transport system, permease component
KMCOHGGH_01203 1.7e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
KMCOHGGH_01204 2.5e-178 yjlA EG Putative multidrug resistance efflux transporter
KMCOHGGH_01205 6.8e-92 yjlB S Cupin domain
KMCOHGGH_01206 7e-66 yjlC S Protein of unknown function (DUF1641)
KMCOHGGH_01207 1.3e-218 yjlD 1.6.99.3 C NADH dehydrogenase
KMCOHGGH_01208 5.6e-277 uxaC 5.3.1.12 G glucuronate isomerase
KMCOHGGH_01209 3e-254 yjmB G symporter YjmB
KMCOHGGH_01210 3.4e-183 exuR K transcriptional
KMCOHGGH_01211 1.2e-277 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KMCOHGGH_01212 1.5e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KMCOHGGH_01213 1.5e-130 MA20_18170 S membrane transporter protein
KMCOHGGH_01214 1.5e-77 yjoA S DinB family
KMCOHGGH_01215 9.3e-214 S response regulator aspartate phosphatase
KMCOHGGH_01217 1.9e-167 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KMCOHGGH_01218 1.4e-31 yjqA S Bacterial PH domain
KMCOHGGH_01219 3.6e-111 yjqB S phage-related replication protein
KMCOHGGH_01220 1.3e-110 xkdA E IrrE N-terminal-like domain
KMCOHGGH_01221 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
KMCOHGGH_01223 2.5e-152 xkdC L Bacterial dnaA protein
KMCOHGGH_01226 2e-10 yqaO S Phage-like element PBSX protein XtrA
KMCOHGGH_01227 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KMCOHGGH_01228 1.2e-109 xtmA L phage terminase small subunit
KMCOHGGH_01229 6.1e-209 xtmB S phage terminase, large subunit
KMCOHGGH_01230 4.6e-242 yqbA S portal protein
KMCOHGGH_01231 5.7e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
KMCOHGGH_01232 1e-157 xkdG S Phage capsid family
KMCOHGGH_01233 3.3e-46 yqbG S Protein of unknown function (DUF3199)
KMCOHGGH_01234 4.2e-43 yqbH S Domain of unknown function (DUF3599)
KMCOHGGH_01235 1.4e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
KMCOHGGH_01236 2.2e-57 xkdJ
KMCOHGGH_01237 3.1e-14
KMCOHGGH_01238 2.2e-225 xkdK S Phage tail sheath C-terminal domain
KMCOHGGH_01239 2e-74 xkdM S Phage tail tube protein
KMCOHGGH_01240 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
KMCOHGGH_01241 3.4e-19
KMCOHGGH_01242 1.5e-202 xkdO L Transglycosylase SLT domain
KMCOHGGH_01243 6.2e-109 xkdP S Lysin motif
KMCOHGGH_01244 1.8e-160 xkdQ 3.2.1.96 G NLP P60 protein
KMCOHGGH_01245 7.2e-32 xkdR S Protein of unknown function (DUF2577)
KMCOHGGH_01246 4.2e-58 xkdS S Protein of unknown function (DUF2634)
KMCOHGGH_01247 1.8e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KMCOHGGH_01248 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KMCOHGGH_01249 1.2e-26
KMCOHGGH_01250 5.5e-90
KMCOHGGH_01252 1.5e-29 xkdX
KMCOHGGH_01253 2.5e-138 xepA
KMCOHGGH_01254 8.7e-38 xhlA S Haemolysin XhlA
KMCOHGGH_01255 1.3e-38 xhlB S SPP1 phage holin
KMCOHGGH_01256 6.4e-170 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KMCOHGGH_01257 8.7e-23 spoIISB S Stage II sporulation protein SB
KMCOHGGH_01258 1.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KMCOHGGH_01259 2e-175 pit P phosphate transporter
KMCOHGGH_01260 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KMCOHGGH_01261 1.5e-242 steT E amino acid
KMCOHGGH_01262 1.9e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KMCOHGGH_01263 3e-311 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KMCOHGGH_01264 1.4e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KMCOHGGH_01266 5e-206 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMCOHGGH_01267 4.3e-286 yubD P Major Facilitator Superfamily
KMCOHGGH_01269 6.5e-156 dppA E D-aminopeptidase
KMCOHGGH_01270 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMCOHGGH_01271 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMCOHGGH_01272 7.7e-191 dppD P Belongs to the ABC transporter superfamily
KMCOHGGH_01273 0.0 dppE E ABC transporter substrate-binding protein
KMCOHGGH_01274 2.6e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KMCOHGGH_01275 1.8e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KMCOHGGH_01276 3.2e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KMCOHGGH_01277 3.6e-182 ykfD E Belongs to the ABC transporter superfamily
KMCOHGGH_01278 1.5e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
KMCOHGGH_01279 1.3e-159 ykgA E Amidinotransferase
KMCOHGGH_01280 4.1e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KMCOHGGH_01281 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KMCOHGGH_01282 2.7e-52 ykkC P Multidrug resistance protein
KMCOHGGH_01283 3.4e-49 ykkD P Multidrug resistance protein
KMCOHGGH_01284 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KMCOHGGH_01285 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KMCOHGGH_01286 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KMCOHGGH_01287 5.7e-71 ohrA O Organic hydroperoxide resistance protein
KMCOHGGH_01288 2.2e-85 ohrR K COG1846 Transcriptional regulators
KMCOHGGH_01289 4.2e-71 ohrB O Organic hydroperoxide resistance protein
KMCOHGGH_01290 1.2e-58 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KMCOHGGH_01292 6.4e-215 M Glycosyl transferase family 2
KMCOHGGH_01293 3.1e-122 M PFAM Collagen triple helix repeat (20 copies)
KMCOHGGH_01294 9.4e-217 hcaT 1.5.1.2 EGP Major facilitator Superfamily
KMCOHGGH_01295 3.1e-119 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KMCOHGGH_01296 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KMCOHGGH_01297 2.9e-176 isp O Belongs to the peptidase S8 family
KMCOHGGH_01298 1.2e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMCOHGGH_01299 2.1e-132 ykoC P Cobalt transport protein
KMCOHGGH_01300 5.7e-305 P ABC transporter, ATP-binding protein
KMCOHGGH_01301 2e-98 ykoE S ABC-type cobalt transport system, permease component
KMCOHGGH_01302 1e-245 ydhD M Glycosyl hydrolase
KMCOHGGH_01304 5e-238 mgtE P Acts as a magnesium transporter
KMCOHGGH_01305 5.4e-53 tnrA K transcriptional
KMCOHGGH_01306 1.9e-16
KMCOHGGH_01307 3.1e-26 ykoL
KMCOHGGH_01308 5e-81 ykoM K transcriptional
KMCOHGGH_01309 2.2e-99 ykoP G polysaccharide deacetylase
KMCOHGGH_01310 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KMCOHGGH_01311 1.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KMCOHGGH_01312 4.1e-101 ykoX S membrane-associated protein
KMCOHGGH_01313 2.7e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KMCOHGGH_01314 1.3e-126 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMCOHGGH_01315 8.1e-120 rsgI S Anti-sigma factor N-terminus
KMCOHGGH_01316 2.5e-26 sspD S small acid-soluble spore protein
KMCOHGGH_01317 7.8e-126 ykrK S Domain of unknown function (DUF1836)
KMCOHGGH_01318 4.1e-156 htpX O Belongs to the peptidase M48B family
KMCOHGGH_01319 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_01320 1.1e-40 L transposase activity
KMCOHGGH_01321 1.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
KMCOHGGH_01322 1.5e-113 ydfR S Protein of unknown function (DUF421)
KMCOHGGH_01323 1.1e-22 ykzE
KMCOHGGH_01324 2e-191 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KMCOHGGH_01325 0.0 kinE 2.7.13.3 T Histidine kinase
KMCOHGGH_01326 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KMCOHGGH_01328 1.7e-193 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KMCOHGGH_01329 2.1e-224 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KMCOHGGH_01330 7.7e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KMCOHGGH_01331 1.1e-228 mtnE 2.6.1.83 E Aminotransferase
KMCOHGGH_01332 6.1e-227 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KMCOHGGH_01333 4.4e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KMCOHGGH_01334 2.7e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KMCOHGGH_01335 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KMCOHGGH_01336 2.6e-10 S Spo0E like sporulation regulatory protein
KMCOHGGH_01337 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KMCOHGGH_01338 1.5e-77 ykvE K transcriptional
KMCOHGGH_01339 2.7e-127 motB N Flagellar motor protein
KMCOHGGH_01340 1.1e-136 motA N flagellar motor
KMCOHGGH_01341 0.0 clpE O Belongs to the ClpA ClpB family
KMCOHGGH_01342 4.1e-184 ykvI S membrane
KMCOHGGH_01343 5.5e-190
KMCOHGGH_01344 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KMCOHGGH_01345 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KMCOHGGH_01346 2.2e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KMCOHGGH_01347 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KMCOHGGH_01348 6.6e-60 ykvN K HxlR-like helix-turn-helix
KMCOHGGH_01349 7.7e-132 IQ Enoyl-(Acyl carrier protein) reductase
KMCOHGGH_01350 1.1e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KMCOHGGH_01351 7.8e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
KMCOHGGH_01352 3.9e-34 3.5.1.104 M LysM domain
KMCOHGGH_01353 9e-162 G Glycosyl hydrolases family 18
KMCOHGGH_01355 1.3e-44 ykvR S Protein of unknown function (DUF3219)
KMCOHGGH_01356 7.8e-25 ykvS S protein conserved in bacteria
KMCOHGGH_01357 2.3e-27
KMCOHGGH_01358 6.3e-111 ykvT 3.5.1.28 M Cell Wall Hydrolase
KMCOHGGH_01359 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMCOHGGH_01360 2.7e-88 stoA CO thiol-disulfide
KMCOHGGH_01361 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KMCOHGGH_01362 7.4e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KMCOHGGH_01364 2.3e-176 ykvZ 5.1.1.1 K Transcriptional regulator
KMCOHGGH_01365 7.3e-155 glcT K antiterminator
KMCOHGGH_01366 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMCOHGGH_01367 2.1e-39 ptsH G phosphocarrier protein HPr
KMCOHGGH_01368 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KMCOHGGH_01369 6.1e-38 splA S Transcriptional regulator
KMCOHGGH_01370 7.2e-189 splB 4.1.99.14 L Spore photoproduct lyase
KMCOHGGH_01371 8.2e-266 mcpC NT chemotaxis protein
KMCOHGGH_01372 7.3e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KMCOHGGH_01373 4e-115 ykwD J protein with SCP PR1 domains
KMCOHGGH_01374 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KMCOHGGH_01375 1.2e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
KMCOHGGH_01376 2.5e-214 patA 2.6.1.1 E Aminotransferase
KMCOHGGH_01377 2.3e-09
KMCOHGGH_01378 1.8e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
KMCOHGGH_01379 1.4e-83 ykyB S YkyB-like protein
KMCOHGGH_01380 1.5e-239 ykuC EGP Major facilitator Superfamily
KMCOHGGH_01381 1.2e-88 ykuD S protein conserved in bacteria
KMCOHGGH_01382 3e-156 ykuE S Metallophosphoesterase
KMCOHGGH_01383 3.8e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMCOHGGH_01385 1.5e-233 ykuI T Diguanylate phosphodiesterase
KMCOHGGH_01386 3.9e-37 ykuJ S protein conserved in bacteria
KMCOHGGH_01387 4.9e-93 ykuK S Ribonuclease H-like
KMCOHGGH_01388 2.5e-26 ykzF S Antirepressor AbbA
KMCOHGGH_01389 1e-75 ykuL S CBS domain
KMCOHGGH_01390 6e-168 ccpC K Transcriptional regulator
KMCOHGGH_01391 8.7e-89 fld C Flavodoxin
KMCOHGGH_01392 9.4e-169 ykuO
KMCOHGGH_01393 9.3e-80 fld C Flavodoxin
KMCOHGGH_01394 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KMCOHGGH_01395 1.5e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KMCOHGGH_01396 4.8e-38 ykuS S Belongs to the UPF0180 family
KMCOHGGH_01397 1.7e-140 ykuT M Mechanosensitive ion channel
KMCOHGGH_01398 1.1e-80 ykuV CO thiol-disulfide
KMCOHGGH_01399 4.5e-98 rok K Repressor of ComK
KMCOHGGH_01400 1.1e-162 yknT
KMCOHGGH_01401 4.8e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KMCOHGGH_01402 1.9e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KMCOHGGH_01403 1.2e-241 moeA 2.10.1.1 H molybdopterin
KMCOHGGH_01404 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KMCOHGGH_01405 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KMCOHGGH_01406 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KMCOHGGH_01407 1.6e-102 yknW S Yip1 domain
KMCOHGGH_01408 8.9e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KMCOHGGH_01409 6.1e-123 macB V ABC transporter, ATP-binding protein
KMCOHGGH_01410 4.9e-213 yknZ V ABC transporter (permease)
KMCOHGGH_01411 1.1e-133 fruR K Transcriptional regulator
KMCOHGGH_01412 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KMCOHGGH_01413 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KMCOHGGH_01414 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KMCOHGGH_01415 1.2e-37 ykoA
KMCOHGGH_01416 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KMCOHGGH_01417 1.2e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMCOHGGH_01418 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KMCOHGGH_01419 5.5e-12 S Uncharacterized protein YkpC
KMCOHGGH_01420 6.9e-184 mreB D Rod-share determining protein MreBH
KMCOHGGH_01421 2.1e-45 abrB K of stationary sporulation gene expression
KMCOHGGH_01422 3.7e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KMCOHGGH_01423 3.1e-150 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KMCOHGGH_01424 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
KMCOHGGH_01425 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KMCOHGGH_01426 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMCOHGGH_01427 8.2e-31 ykzG S Belongs to the UPF0356 family
KMCOHGGH_01428 1.4e-147 ykrA S hydrolases of the HAD superfamily
KMCOHGGH_01429 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KMCOHGGH_01431 5.8e-104 recN L Putative cell-wall binding lipoprotein
KMCOHGGH_01432 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KMCOHGGH_01433 0.0 Q Polyketide synthase of type I
KMCOHGGH_01434 0.0 Q polyketide synthase
KMCOHGGH_01435 0.0 Q Polyketide synthase of type I
KMCOHGGH_01436 0.0 Q Polyketide synthase of type I
KMCOHGGH_01437 0.0 Q Polyketide synthase of type I
KMCOHGGH_01438 0.0 Q Polyketide synthase of type I
KMCOHGGH_01439 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
KMCOHGGH_01440 3.8e-212 V Beta-lactamase
KMCOHGGH_01441 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMCOHGGH_01442 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMCOHGGH_01443 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMCOHGGH_01444 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMCOHGGH_01445 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KMCOHGGH_01446 3.7e-140 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
KMCOHGGH_01447 7e-278 speA 4.1.1.19 E Arginine
KMCOHGGH_01448 1.6e-42 yktA S Belongs to the UPF0223 family
KMCOHGGH_01449 4.9e-119 yktB S Belongs to the UPF0637 family
KMCOHGGH_01450 9.7e-25 ykzI
KMCOHGGH_01451 2.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
KMCOHGGH_01452 5.2e-83 ykzC S Acetyltransferase (GNAT) family
KMCOHGGH_01453 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KMCOHGGH_01454 2.8e-13 sigC S Putative zinc-finger
KMCOHGGH_01455 7e-38 ylaE
KMCOHGGH_01456 6.7e-24 S Family of unknown function (DUF5325)
KMCOHGGH_01457 0.0 typA T GTP-binding protein TypA
KMCOHGGH_01458 3.9e-48 ylaH S YlaH-like protein
KMCOHGGH_01459 1e-33 ylaI S protein conserved in bacteria
KMCOHGGH_01460 2e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMCOHGGH_01461 8.3e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KMCOHGGH_01462 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KMCOHGGH_01463 5.4e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
KMCOHGGH_01464 8.7e-44 ylaN S Belongs to the UPF0358 family
KMCOHGGH_01465 9e-215 ftsW D Belongs to the SEDS family
KMCOHGGH_01466 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KMCOHGGH_01467 2.9e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KMCOHGGH_01468 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KMCOHGGH_01469 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KMCOHGGH_01470 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KMCOHGGH_01471 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KMCOHGGH_01472 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KMCOHGGH_01473 9.7e-166 ctaG S cytochrome c oxidase
KMCOHGGH_01474 8.5e-60 ylbA S YugN-like family
KMCOHGGH_01475 2.4e-72 ylbB T COG0517 FOG CBS domain
KMCOHGGH_01476 2.1e-199 ylbC S protein with SCP PR1 domains
KMCOHGGH_01477 6.5e-56 ylbD S Putative coat protein
KMCOHGGH_01478 8.8e-37 ylbE S YlbE-like protein
KMCOHGGH_01479 1.2e-71 ylbF S Belongs to the UPF0342 family
KMCOHGGH_01480 5.5e-43 ylbG S UPF0298 protein
KMCOHGGH_01482 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
KMCOHGGH_01483 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KMCOHGGH_01484 1.3e-216 ylbJ S Sporulation integral membrane protein YlbJ
KMCOHGGH_01485 8.9e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
KMCOHGGH_01486 2.1e-188 ylbL T Belongs to the peptidase S16 family
KMCOHGGH_01487 3.3e-228 ylbM S Belongs to the UPF0348 family
KMCOHGGH_01488 7.8e-91 yceD S metal-binding, possibly nucleic acid-binding protein
KMCOHGGH_01489 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KMCOHGGH_01490 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KMCOHGGH_01491 1.2e-88 ylbP K n-acetyltransferase
KMCOHGGH_01492 1.1e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMCOHGGH_01493 9.3e-311 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KMCOHGGH_01494 8.9e-78 mraZ K Belongs to the MraZ family
KMCOHGGH_01495 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KMCOHGGH_01496 2.9e-52 ftsL D Essential cell division protein
KMCOHGGH_01497 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KMCOHGGH_01498 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KMCOHGGH_01499 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KMCOHGGH_01500 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KMCOHGGH_01501 1.3e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KMCOHGGH_01502 2.2e-185 spoVE D Belongs to the SEDS family
KMCOHGGH_01503 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KMCOHGGH_01504 5.6e-169 murB 1.3.1.98 M cell wall formation
KMCOHGGH_01505 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KMCOHGGH_01506 1e-227 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KMCOHGGH_01507 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KMCOHGGH_01508 0.0 bpr O COG1404 Subtilisin-like serine proteases
KMCOHGGH_01509 4.1e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KMCOHGGH_01510 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMCOHGGH_01511 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMCOHGGH_01512 5e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KMCOHGGH_01513 5.2e-253 argE 3.5.1.16 E Acetylornithine deacetylase
KMCOHGGH_01514 2.2e-38 ylmC S sporulation protein
KMCOHGGH_01515 3.4e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KMCOHGGH_01516 7.2e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KMCOHGGH_01517 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KMCOHGGH_01518 5.2e-41 yggT S membrane
KMCOHGGH_01519 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KMCOHGGH_01520 8.9e-68 divIVA D Cell division initiation protein
KMCOHGGH_01521 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KMCOHGGH_01522 3.4e-64 dksA T COG1734 DnaK suppressor protein
KMCOHGGH_01523 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KMCOHGGH_01524 4.6e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KMCOHGGH_01525 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KMCOHGGH_01526 8e-233 pyrP F Xanthine uracil
KMCOHGGH_01527 1.6e-168 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KMCOHGGH_01528 5e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KMCOHGGH_01529 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KMCOHGGH_01530 0.0 carB 6.3.5.5 F Belongs to the CarB family
KMCOHGGH_01531 1.1e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KMCOHGGH_01532 3e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KMCOHGGH_01533 9.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KMCOHGGH_01534 1.9e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KMCOHGGH_01536 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KMCOHGGH_01537 3.9e-177 cysP P phosphate transporter
KMCOHGGH_01538 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KMCOHGGH_01539 1.9e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KMCOHGGH_01540 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KMCOHGGH_01541 5.8e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KMCOHGGH_01542 8.5e-79 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KMCOHGGH_01543 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KMCOHGGH_01544 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KMCOHGGH_01545 7.7e-155 yloC S stress-induced protein
KMCOHGGH_01546 1.5e-40 ylzA S Belongs to the UPF0296 family
KMCOHGGH_01547 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KMCOHGGH_01548 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KMCOHGGH_01549 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KMCOHGGH_01550 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KMCOHGGH_01551 2.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KMCOHGGH_01552 8.6e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KMCOHGGH_01553 3.3e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KMCOHGGH_01554 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KMCOHGGH_01555 1.7e-139 stp 3.1.3.16 T phosphatase
KMCOHGGH_01556 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KMCOHGGH_01557 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KMCOHGGH_01558 1.8e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KMCOHGGH_01559 8.4e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
KMCOHGGH_01560 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KMCOHGGH_01561 5.5e-59 asp S protein conserved in bacteria
KMCOHGGH_01562 4.9e-304 yloV S kinase related to dihydroxyacetone kinase
KMCOHGGH_01563 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
KMCOHGGH_01564 3.9e-154 sdaAA 4.3.1.17 E L-serine dehydratase
KMCOHGGH_01565 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KMCOHGGH_01566 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KMCOHGGH_01567 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KMCOHGGH_01568 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KMCOHGGH_01569 4.6e-129 IQ reductase
KMCOHGGH_01570 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMCOHGGH_01571 2.6e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KMCOHGGH_01572 0.0 smc D Required for chromosome condensation and partitioning
KMCOHGGH_01573 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KMCOHGGH_01574 3.4e-143 S Phosphotransferase enzyme family
KMCOHGGH_01575 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KMCOHGGH_01576 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KMCOHGGH_01577 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KMCOHGGH_01578 1.7e-35 ylqC S Belongs to the UPF0109 family
KMCOHGGH_01579 1.3e-61 ylqD S YlqD protein
KMCOHGGH_01580 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KMCOHGGH_01581 8.3e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KMCOHGGH_01582 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KMCOHGGH_01583 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KMCOHGGH_01584 2e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMCOHGGH_01585 9.2e-306 ylqG
KMCOHGGH_01586 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KMCOHGGH_01587 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KMCOHGGH_01588 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KMCOHGGH_01589 1.5e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KMCOHGGH_01590 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMCOHGGH_01591 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KMCOHGGH_01592 7.2e-172 xerC L tyrosine recombinase XerC
KMCOHGGH_01593 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KMCOHGGH_01594 1.6e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KMCOHGGH_01595 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KMCOHGGH_01596 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KMCOHGGH_01597 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
KMCOHGGH_01598 2.5e-31 fliE N Flagellar hook-basal body
KMCOHGGH_01599 2e-262 fliF N The M ring may be actively involved in energy transduction
KMCOHGGH_01600 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KMCOHGGH_01601 1.4e-88 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KMCOHGGH_01602 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KMCOHGGH_01603 4.5e-71 fliJ N Flagellar biosynthesis chaperone
KMCOHGGH_01604 4.4e-48 ylxF S MgtE intracellular N domain
KMCOHGGH_01605 7.2e-205 fliK N Flagellar hook-length control protein
KMCOHGGH_01606 1.4e-72 flgD N Flagellar basal body rod modification protein
KMCOHGGH_01607 4e-139 flgG N Flagellar basal body rod
KMCOHGGH_01608 9.2e-58 fliL N Controls the rotational direction of flagella during chemotaxis
KMCOHGGH_01609 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KMCOHGGH_01610 2.7e-189 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KMCOHGGH_01611 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KMCOHGGH_01612 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
KMCOHGGH_01613 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
KMCOHGGH_01614 2e-37 fliQ N Role in flagellar biosynthesis
KMCOHGGH_01615 5.2e-131 fliR N Flagellar biosynthetic protein FliR
KMCOHGGH_01616 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KMCOHGGH_01617 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KMCOHGGH_01618 3e-193 flhF N Flagellar biosynthesis regulator FlhF
KMCOHGGH_01619 1.6e-155 flhG D Belongs to the ParA family
KMCOHGGH_01620 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KMCOHGGH_01621 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KMCOHGGH_01622 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
KMCOHGGH_01623 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KMCOHGGH_01624 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KMCOHGGH_01625 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMCOHGGH_01626 2.7e-50 ylxL
KMCOHGGH_01627 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
KMCOHGGH_01628 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KMCOHGGH_01629 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KMCOHGGH_01630 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KMCOHGGH_01631 2.2e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KMCOHGGH_01632 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
KMCOHGGH_01633 1.9e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KMCOHGGH_01634 1.5e-233 rasP M zinc metalloprotease
KMCOHGGH_01635 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KMCOHGGH_01636 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMCOHGGH_01637 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KMCOHGGH_01638 5.4e-206 nusA K Participates in both transcription termination and antitermination
KMCOHGGH_01639 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
KMCOHGGH_01640 1.8e-47 ylxQ J ribosomal protein
KMCOHGGH_01641 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KMCOHGGH_01642 3.9e-44 ylxP S protein conserved in bacteria
KMCOHGGH_01643 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KMCOHGGH_01644 3.6e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KMCOHGGH_01645 6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KMCOHGGH_01646 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KMCOHGGH_01647 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KMCOHGGH_01648 3e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KMCOHGGH_01649 1.8e-234 pepR S Belongs to the peptidase M16 family
KMCOHGGH_01650 2.6e-42 ymxH S YlmC YmxH family
KMCOHGGH_01651 1.2e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KMCOHGGH_01652 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KMCOHGGH_01653 7.6e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KMCOHGGH_01654 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KMCOHGGH_01655 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KMCOHGGH_01656 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMCOHGGH_01657 7.6e-132 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KMCOHGGH_01658 6.3e-31 S YlzJ-like protein
KMCOHGGH_01659 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KMCOHGGH_01660 1.8e-133 ymfC K Transcriptional regulator
KMCOHGGH_01661 2.4e-229 ymfD EGP Major facilitator Superfamily
KMCOHGGH_01662 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
KMCOHGGH_01663 0.0 ydgH S drug exporters of the RND superfamily
KMCOHGGH_01664 4e-237 ymfF S Peptidase M16
KMCOHGGH_01665 1.2e-244 ymfH S zinc protease
KMCOHGGH_01666 6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KMCOHGGH_01667 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
KMCOHGGH_01668 3.5e-143 ymfK S Protein of unknown function (DUF3388)
KMCOHGGH_01669 1.7e-125 ymfM S protein conserved in bacteria
KMCOHGGH_01670 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KMCOHGGH_01671 1.7e-232 cinA 3.5.1.42 S Belongs to the CinA family
KMCOHGGH_01672 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KMCOHGGH_01673 5e-194 pbpX V Beta-lactamase
KMCOHGGH_01674 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
KMCOHGGH_01675 4.9e-153 ymdB S protein conserved in bacteria
KMCOHGGH_01676 1.2e-36 spoVS S Stage V sporulation protein S
KMCOHGGH_01677 1.5e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KMCOHGGH_01678 6.7e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KMCOHGGH_01679 1e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KMCOHGGH_01680 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KMCOHGGH_01681 1.7e-88 cotE S Spore coat protein
KMCOHGGH_01682 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KMCOHGGH_01683 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KMCOHGGH_01684 1.3e-68 L Belongs to the 'phage' integrase family
KMCOHGGH_01685 9.1e-31
KMCOHGGH_01687 3.3e-129 pksB 3.1.2.6 S Polyketide biosynthesis
KMCOHGGH_01688 2.9e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KMCOHGGH_01689 5.6e-183 pksD Q Acyl transferase domain
KMCOHGGH_01690 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KMCOHGGH_01691 6.5e-35 acpK IQ Phosphopantetheine attachment site
KMCOHGGH_01692 6.9e-242 pksG 2.3.3.10 I synthase
KMCOHGGH_01693 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
KMCOHGGH_01694 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KMCOHGGH_01695 0.0 rhiB IQ polyketide synthase
KMCOHGGH_01696 0.0 Q Polyketide synthase of type I
KMCOHGGH_01697 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
KMCOHGGH_01698 0.0 dhbF IQ polyketide synthase
KMCOHGGH_01699 0.0 pks13 HQ Beta-ketoacyl synthase
KMCOHGGH_01700 2.4e-231 cypA C Cytochrome P450
KMCOHGGH_01701 3.2e-77 nucB M Deoxyribonuclease NucA/NucB
KMCOHGGH_01702 3.6e-118 yoaK S Membrane
KMCOHGGH_01703 1.1e-40 L transposase activity
KMCOHGGH_01704 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_01705 1.4e-62 ymzB
KMCOHGGH_01706 1.8e-256 aprX O Belongs to the peptidase S8 family
KMCOHGGH_01708 4.1e-127 ymaC S Replication protein
KMCOHGGH_01709 3.9e-78 ymaD O redox protein, regulator of disulfide bond formation
KMCOHGGH_01710 5.2e-54 ebrB P Small Multidrug Resistance protein
KMCOHGGH_01711 3.1e-48 ebrA P Small Multidrug Resistance protein
KMCOHGGH_01713 4.1e-47 ymaF S YmaF family
KMCOHGGH_01714 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KMCOHGGH_01715 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KMCOHGGH_01716 8.5e-44
KMCOHGGH_01717 1.8e-20 ymzA
KMCOHGGH_01718 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KMCOHGGH_01719 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMCOHGGH_01720 1.3e-182 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMCOHGGH_01721 2.4e-110 ymaB S MutT family
KMCOHGGH_01722 1.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KMCOHGGH_01723 1.3e-176 spoVK O stage V sporulation protein K
KMCOHGGH_01724 2.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KMCOHGGH_01725 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KMCOHGGH_01726 4.3e-68 glnR K transcriptional
KMCOHGGH_01727 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
KMCOHGGH_01728 1.4e-214 mrjp G Major royal jelly protein
KMCOHGGH_01729 9.6e-253 xynT G MFS/sugar transport protein
KMCOHGGH_01730 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
KMCOHGGH_01731 3.2e-217 xylR GK ROK family
KMCOHGGH_01732 5.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KMCOHGGH_01733 3.2e-286 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
KMCOHGGH_01734 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
KMCOHGGH_01737 5.4e-17
KMCOHGGH_01738 1.9e-186 adhP 1.1.1.1 C alcohol dehydrogenase
KMCOHGGH_01739 8.6e-11 ccmM S Bacterial transferase hexapeptide (six repeats)
KMCOHGGH_01740 4.2e-16
KMCOHGGH_01742 1.8e-43
KMCOHGGH_01744 3.1e-144 yoaP 3.1.3.18 K YoaP-like
KMCOHGGH_01745 7.4e-100 J Acetyltransferase (GNAT) domain
KMCOHGGH_01746 7.8e-60
KMCOHGGH_01748 1.6e-42 ynaE S Domain of unknown function (DUF3885)
KMCOHGGH_01749 3.2e-52 ynaE S Domain of unknown function (DUF3885)
KMCOHGGH_01750 2.3e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMCOHGGH_01751 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
KMCOHGGH_01753 6.5e-64 2.3.1.128 J Acetyltransferase (GNAT) domain
KMCOHGGH_01754 3.5e-94 yvgO
KMCOHGGH_01756 0.0 yobO M Pectate lyase superfamily protein
KMCOHGGH_01757 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KMCOHGGH_01758 3e-145 yndL S Replication protein
KMCOHGGH_01759 1.6e-07
KMCOHGGH_01760 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
KMCOHGGH_01761 2.7e-71 yndM S Protein of unknown function (DUF2512)
KMCOHGGH_01762 2.4e-13 yoaW
KMCOHGGH_01763 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KMCOHGGH_01764 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KMCOHGGH_01765 3.5e-112 yneB L resolvase
KMCOHGGH_01766 2.8e-32 ynzC S UPF0291 protein
KMCOHGGH_01767 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KMCOHGGH_01768 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
KMCOHGGH_01769 2.3e-28 yneF S UPF0154 protein
KMCOHGGH_01770 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
KMCOHGGH_01771 2.3e-125 ccdA O cytochrome c biogenesis protein
KMCOHGGH_01772 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KMCOHGGH_01773 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KMCOHGGH_01774 8.5e-75 yneK S Protein of unknown function (DUF2621)
KMCOHGGH_01775 3.2e-62 hspX O Spore coat protein
KMCOHGGH_01776 2.3e-19 sspP S Belongs to the SspP family
KMCOHGGH_01777 7.5e-15 sspO S Belongs to the SspO family
KMCOHGGH_01778 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KMCOHGGH_01779 1.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KMCOHGGH_01781 2.7e-33 tlp S Belongs to the Tlp family
KMCOHGGH_01782 8.3e-75 yneP S Thioesterase-like superfamily
KMCOHGGH_01783 4.4e-54 yneQ
KMCOHGGH_01784 1.3e-50 yneR S Belongs to the HesB IscA family
KMCOHGGH_01785 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KMCOHGGH_01786 1.5e-68 yccU S CoA-binding protein
KMCOHGGH_01787 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KMCOHGGH_01788 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KMCOHGGH_01789 1.6e-13
KMCOHGGH_01790 1.1e-40 ynfC
KMCOHGGH_01791 1.6e-250 agcS E Sodium alanine symporter
KMCOHGGH_01792 1.1e-40 L transposase activity
KMCOHGGH_01793 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_01794 3e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KMCOHGGH_01795 1.4e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KMCOHGGH_01796 8.9e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KMCOHGGH_01797 7e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KMCOHGGH_01798 7e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMCOHGGH_01799 6.4e-182 kdgR_1 K transcriptional
KMCOHGGH_01800 1.2e-222 exuT G Sugar (and other) transporter
KMCOHGGH_01801 4.4e-157 yndG S DoxX-like family
KMCOHGGH_01802 2.3e-78 yndH S Domain of unknown function (DUF4166)
KMCOHGGH_01803 1.5e-302 yndJ S YndJ-like protein
KMCOHGGH_01804 1e-215 S Platelet-activating factor acetylhydrolase, isoform II
KMCOHGGH_01805 5.1e-292 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KMCOHGGH_01806 2.8e-51 S Domain of unknown function (DUF4870)
KMCOHGGH_01807 2.8e-236 T PhoQ Sensor
KMCOHGGH_01808 2.2e-128 T Transcriptional regulatory protein, C terminal
KMCOHGGH_01809 4.3e-252 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
KMCOHGGH_01810 3.5e-288 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KMCOHGGH_01811 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_01812 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_01813 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_01814 1.3e-221 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KMCOHGGH_01815 1.8e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KMCOHGGH_01816 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KMCOHGGH_01817 3.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KMCOHGGH_01818 1.9e-256 yxjC EG COG2610 H gluconate symporter and related permeases
KMCOHGGH_01819 2.1e-224 bioI 1.14.14.46 C Cytochrome P450
KMCOHGGH_01820 9.7e-194 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KMCOHGGH_01821 4.4e-129 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KMCOHGGH_01822 1.6e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KMCOHGGH_01823 9.3e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KMCOHGGH_01824 1.3e-145 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KMCOHGGH_01825 3.7e-72 yngA S membrane
KMCOHGGH_01826 6.2e-160 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KMCOHGGH_01827 3.2e-104 yngC S SNARE associated Golgi protein
KMCOHGGH_01828 5.7e-291 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KMCOHGGH_01829 5.2e-139 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KMCOHGGH_01830 2.5e-169 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KMCOHGGH_01831 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KMCOHGGH_01832 3.5e-252 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KMCOHGGH_01833 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMCOHGGH_01834 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KMCOHGGH_01835 2e-304 yngK T Glycosyl hydrolase-like 10
KMCOHGGH_01836 4.1e-65 yngL S Protein of unknown function (DUF1360)
KMCOHGGH_01837 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
KMCOHGGH_01838 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_01839 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_01840 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_01841 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_01842 1.7e-268 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KMCOHGGH_01843 1.3e-184 yoxA 5.1.3.3 G Aldose 1-epimerase
KMCOHGGH_01844 2.7e-247 yoeA V MATE efflux family protein
KMCOHGGH_01845 1.3e-96 yoeB S IseA DL-endopeptidase inhibitor
KMCOHGGH_01847 2.2e-96 L Integrase
KMCOHGGH_01848 1.8e-34 yoeD G Helix-turn-helix domain
KMCOHGGH_01849 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KMCOHGGH_01850 1.2e-200 ybcL EGP Major facilitator Superfamily
KMCOHGGH_01851 6.7e-50 ybzH K Helix-turn-helix domain
KMCOHGGH_01852 2.8e-271 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KMCOHGGH_01853 2.3e-156 gltR1 K Transcriptional regulator
KMCOHGGH_01854 1.7e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KMCOHGGH_01855 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KMCOHGGH_01856 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KMCOHGGH_01857 8.7e-146 gltC K Transcriptional regulator
KMCOHGGH_01858 1.3e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KMCOHGGH_01859 2e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMCOHGGH_01860 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KMCOHGGH_01861 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KMCOHGGH_01862 2.2e-40 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KMCOHGGH_01863 9.3e-141 yoxB
KMCOHGGH_01864 1.5e-204 yoaB EGP Major facilitator Superfamily
KMCOHGGH_01865 1.4e-273 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
KMCOHGGH_01866 1.9e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMCOHGGH_01867 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMCOHGGH_01868 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_01869 1.1e-40 L transposase activity
KMCOHGGH_01870 1.1e-25 yoaF
KMCOHGGH_01872 5.6e-98 hpr K helix_turn_helix multiple antibiotic resistance protein
KMCOHGGH_01873 3.9e-44
KMCOHGGH_01874 3.6e-55 S SMI1-KNR4 cell-wall
KMCOHGGH_01875 3.8e-302 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KMCOHGGH_01876 1.9e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KMCOHGGH_01877 7.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
KMCOHGGH_01878 3.1e-93 yobS K Transcriptional regulator
KMCOHGGH_01879 3.8e-136 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KMCOHGGH_01880 1.9e-92 yobW
KMCOHGGH_01881 1.7e-54 czrA K transcriptional
KMCOHGGH_01882 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KMCOHGGH_01883 2.8e-91 yozB S membrane
KMCOHGGH_01884 5.6e-141 yocB J Protein required for attachment to host cells
KMCOHGGH_01885 1.9e-94 yocC
KMCOHGGH_01886 3.5e-185 yocD 3.4.17.13 V peptidase S66
KMCOHGGH_01888 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
KMCOHGGH_01889 0.0 recQ 3.6.4.12 L DNA helicase
KMCOHGGH_01890 2.8e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KMCOHGGH_01892 2.1e-53 dksA T general stress protein
KMCOHGGH_01893 1.3e-09 yocL
KMCOHGGH_01894 1.7e-08
KMCOHGGH_01895 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
KMCOHGGH_01896 3.8e-44 yozN
KMCOHGGH_01897 8.5e-37 yocN
KMCOHGGH_01898 2.4e-56 yozO S Bacterial PH domain
KMCOHGGH_01900 1.6e-31 yozC
KMCOHGGH_01901 1.1e-286 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KMCOHGGH_01902 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KMCOHGGH_01903 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
KMCOHGGH_01904 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KMCOHGGH_01905 1.8e-160 yocS S -transporter
KMCOHGGH_01906 2.6e-143 S Metallo-beta-lactamase superfamily
KMCOHGGH_01907 1.9e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KMCOHGGH_01908 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KMCOHGGH_01909 0.0 yojO P Von Willebrand factor
KMCOHGGH_01910 5.9e-163 yojN S ATPase family associated with various cellular activities (AAA)
KMCOHGGH_01911 5.9e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KMCOHGGH_01912 3.1e-226 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KMCOHGGH_01913 3e-226 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KMCOHGGH_01914 7.4e-112 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KMCOHGGH_01916 1.1e-240 norM V Multidrug efflux pump
KMCOHGGH_01917 6.5e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMCOHGGH_01918 2.5e-126 yojG S deacetylase
KMCOHGGH_01919 3.7e-60 yojF S Protein of unknown function (DUF1806)
KMCOHGGH_01920 4.9e-23
KMCOHGGH_01921 3.5e-163 rarD S -transporter
KMCOHGGH_01922 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
KMCOHGGH_01924 5.9e-67 yodA S tautomerase
KMCOHGGH_01925 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
KMCOHGGH_01926 1.4e-56 yodB K transcriptional
KMCOHGGH_01927 4.5e-106 yodC C nitroreductase
KMCOHGGH_01928 1.9e-109 mhqD S Carboxylesterase
KMCOHGGH_01929 2e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
KMCOHGGH_01930 1.4e-19 S Protein of unknown function (DUF3311)
KMCOHGGH_01931 1.3e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMCOHGGH_01932 4.7e-282 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
KMCOHGGH_01933 2.7e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KMCOHGGH_01934 5.2e-133 yydK K Transcriptional regulator
KMCOHGGH_01935 4.6e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KMCOHGGH_01936 2.8e-128 yodH Q Methyltransferase
KMCOHGGH_01937 1.1e-34 yodI
KMCOHGGH_01938 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KMCOHGGH_01939 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KMCOHGGH_01941 3.3e-55 yodL S YodL-like
KMCOHGGH_01942 2.8e-103 yodM 3.6.1.27 I Acid phosphatase homologues
KMCOHGGH_01943 6.2e-24 yozD S YozD-like protein
KMCOHGGH_01945 1.7e-125 yodN
KMCOHGGH_01946 4.1e-36 yozE S Belongs to the UPF0346 family
KMCOHGGH_01947 1.4e-46 yokU S YokU-like protein, putative antitoxin
KMCOHGGH_01948 3.2e-280 kamA 5.4.3.2 E lysine 2,3-aminomutase
KMCOHGGH_01949 4.3e-158 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KMCOHGGH_01950 5.1e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
KMCOHGGH_01951 6.1e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KMCOHGGH_01952 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KMCOHGGH_01953 8.1e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMCOHGGH_01954 8.7e-53 yosT L Bacterial transcription activator, effector binding domain
KMCOHGGH_01956 3.2e-144 yiiD K acetyltransferase
KMCOHGGH_01957 2.1e-246 cgeD M maturation of the outermost layer of the spore
KMCOHGGH_01958 1.1e-41 cgeC
KMCOHGGH_01959 1.6e-52 cgeA
KMCOHGGH_01960 1.2e-180 cgeB S Spore maturation protein
KMCOHGGH_01961 1e-220 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KMCOHGGH_01962 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
KMCOHGGH_01964 4.8e-15 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KMCOHGGH_01968 3.6e-76 yoqH M LysM domain
KMCOHGGH_01969 8.1e-194 S aspartate phosphatase
KMCOHGGH_01971 2.8e-39 H Acetyltransferase (GNAT) domain
KMCOHGGH_01972 1.5e-85 yokK S SMI1 / KNR4 family
KMCOHGGH_01973 9.7e-210 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KMCOHGGH_01974 5.6e-84 G SMI1-KNR4 cell-wall
KMCOHGGH_01975 4.1e-77 yokF 3.1.31.1 L RNA catabolic process
KMCOHGGH_01976 1.8e-306 yokA L Recombinase
KMCOHGGH_01977 1.4e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
KMCOHGGH_01978 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KMCOHGGH_01979 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KMCOHGGH_01980 1.4e-66 ypoP K transcriptional
KMCOHGGH_01981 5.5e-98 ypmS S protein conserved in bacteria
KMCOHGGH_01982 8.9e-136 ypmR E GDSL-like Lipase/Acylhydrolase
KMCOHGGH_01983 3e-107 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KMCOHGGH_01984 2.6e-39 ypmP S Protein of unknown function (DUF2535)
KMCOHGGH_01985 8.2e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KMCOHGGH_01986 1.9e-178 pspF K Transcriptional regulator
KMCOHGGH_01987 9.3e-110 hlyIII S protein, Hemolysin III
KMCOHGGH_01988 3.3e-112 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KMCOHGGH_01989 4.8e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KMCOHGGH_01990 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KMCOHGGH_01991 2.7e-114 ypjP S YpjP-like protein
KMCOHGGH_01992 1.1e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KMCOHGGH_01993 1e-75 yphP S Belongs to the UPF0403 family
KMCOHGGH_01994 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KMCOHGGH_01995 7.5e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
KMCOHGGH_01996 2e-98 ypgQ S phosphohydrolase
KMCOHGGH_01997 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KMCOHGGH_01998 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KMCOHGGH_01999 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KMCOHGGH_02000 1e-30 cspD K Cold-shock protein
KMCOHGGH_02001 1.3e-11 degR
KMCOHGGH_02002 1.2e-36 S Protein of unknown function (DUF2564)
KMCOHGGH_02003 1.5e-28 ypeQ S Zinc-finger
KMCOHGGH_02004 1.5e-123 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KMCOHGGH_02005 8.9e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KMCOHGGH_02006 1.6e-67 rnhA 3.1.26.4 L Ribonuclease
KMCOHGGH_02008 4.1e-164 polA 2.7.7.7 L 5'3' exonuclease
KMCOHGGH_02010 1e-38 ypbS S Protein of unknown function (DUF2533)
KMCOHGGH_02011 0.0 ypbR S Dynamin family
KMCOHGGH_02012 3.2e-89 ypbQ S protein conserved in bacteria
KMCOHGGH_02013 2.2e-204 bcsA Q Naringenin-chalcone synthase
KMCOHGGH_02014 2.8e-108 J Acetyltransferase (GNAT) domain
KMCOHGGH_02015 8.9e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
KMCOHGGH_02016 8.7e-09 S Bacillus cereus group antimicrobial protein
KMCOHGGH_02017 2.2e-97 ydfR S Protein of unknown function (DUF421)
KMCOHGGH_02018 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
KMCOHGGH_02020 2.9e-235 pbuX F xanthine
KMCOHGGH_02021 1.5e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KMCOHGGH_02022 5.4e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KMCOHGGH_02023 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KMCOHGGH_02025 6.6e-22 S YpzG-like protein
KMCOHGGH_02026 4.2e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KMCOHGGH_02027 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KMCOHGGH_02028 4.8e-99 ypsA S Belongs to the UPF0398 family
KMCOHGGH_02029 9.9e-33 cotD S Inner spore coat protein D
KMCOHGGH_02031 5.6e-236 yprB L RNase_H superfamily
KMCOHGGH_02032 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KMCOHGGH_02033 2.3e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KMCOHGGH_02034 3.6e-70 hspX O Belongs to the small heat shock protein (HSP20) family
KMCOHGGH_02035 3.4e-47 yppG S YppG-like protein
KMCOHGGH_02037 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
KMCOHGGH_02040 9.2e-186 yppC S Protein of unknown function (DUF2515)
KMCOHGGH_02041 1e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KMCOHGGH_02042 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KMCOHGGH_02043 2.4e-89 ypoC
KMCOHGGH_02044 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KMCOHGGH_02045 6.8e-130 dnaD L DNA replication protein DnaD
KMCOHGGH_02046 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KMCOHGGH_02047 4.8e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KMCOHGGH_02048 4e-81 ypmB S protein conserved in bacteria
KMCOHGGH_02049 6.7e-23 ypmA S Protein of unknown function (DUF4264)
KMCOHGGH_02050 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KMCOHGGH_02051 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KMCOHGGH_02052 1.1e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KMCOHGGH_02053 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KMCOHGGH_02054 2.8e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KMCOHGGH_02055 3.9e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KMCOHGGH_02056 4.1e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KMCOHGGH_02057 6.2e-131 bshB1 S proteins, LmbE homologs
KMCOHGGH_02058 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KMCOHGGH_02059 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KMCOHGGH_02060 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KMCOHGGH_02061 6.2e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KMCOHGGH_02062 5.9e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
KMCOHGGH_02063 7.3e-141 ypjB S sporulation protein
KMCOHGGH_02064 1.2e-103 ypjA S membrane
KMCOHGGH_02065 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KMCOHGGH_02066 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KMCOHGGH_02067 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KMCOHGGH_02068 3.2e-77 ypiF S Protein of unknown function (DUF2487)
KMCOHGGH_02069 2.1e-99 ypiB S Belongs to the UPF0302 family
KMCOHGGH_02070 1e-232 S COG0457 FOG TPR repeat
KMCOHGGH_02071 2e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KMCOHGGH_02072 2.3e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KMCOHGGH_02073 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KMCOHGGH_02074 2.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KMCOHGGH_02075 4.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KMCOHGGH_02076 9.5e-118 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KMCOHGGH_02077 5e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KMCOHGGH_02078 1.2e-159 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KMCOHGGH_02079 4.3e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KMCOHGGH_02080 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KMCOHGGH_02081 9.3e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KMCOHGGH_02082 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KMCOHGGH_02083 7.2e-140 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KMCOHGGH_02084 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KMCOHGGH_02085 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KMCOHGGH_02086 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KMCOHGGH_02087 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KMCOHGGH_02088 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KMCOHGGH_02089 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
KMCOHGGH_02090 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KMCOHGGH_02091 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KMCOHGGH_02092 3.6e-134 yphF
KMCOHGGH_02093 3.3e-16 yphE S Protein of unknown function (DUF2768)
KMCOHGGH_02094 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KMCOHGGH_02095 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KMCOHGGH_02096 1.4e-104 yphA
KMCOHGGH_02097 4.7e-08 S YpzI-like protein
KMCOHGGH_02098 4.5e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KMCOHGGH_02099 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
KMCOHGGH_02100 3.3e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KMCOHGGH_02101 1.4e-12 S Family of unknown function (DUF5359)
KMCOHGGH_02102 2.2e-61 ypfA M Flagellar protein YcgR
KMCOHGGH_02103 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KMCOHGGH_02104 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KMCOHGGH_02105 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
KMCOHGGH_02106 9e-189 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KMCOHGGH_02107 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KMCOHGGH_02108 5.7e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KMCOHGGH_02109 3.6e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
KMCOHGGH_02110 5.7e-85 ypbF S Protein of unknown function (DUF2663)
KMCOHGGH_02111 1.2e-76 ypbE M Lysin motif
KMCOHGGH_02112 9.9e-100 ypbD S metal-dependent membrane protease
KMCOHGGH_02113 2.7e-271 recQ 3.6.4.12 L DNA helicase
KMCOHGGH_02114 7.9e-199 ypbB 5.1.3.1 S protein conserved in bacteria
KMCOHGGH_02115 3.6e-41 fer C Ferredoxin
KMCOHGGH_02116 1.4e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KMCOHGGH_02117 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMCOHGGH_02118 5.4e-198 rsiX
KMCOHGGH_02119 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KMCOHGGH_02120 0.0 resE 2.7.13.3 T Histidine kinase
KMCOHGGH_02121 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_02122 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KMCOHGGH_02123 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KMCOHGGH_02124 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KMCOHGGH_02125 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KMCOHGGH_02126 2.9e-88 spmB S Spore maturation protein
KMCOHGGH_02127 2e-103 spmA S Spore maturation protein
KMCOHGGH_02128 5e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KMCOHGGH_02129 1.1e-92 ypuI S Protein of unknown function (DUF3907)
KMCOHGGH_02130 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KMCOHGGH_02131 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KMCOHGGH_02133 2.9e-93 ypuF S Domain of unknown function (DUF309)
KMCOHGGH_02134 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMCOHGGH_02135 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KMCOHGGH_02136 1.4e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KMCOHGGH_02137 1e-111 ribE 2.5.1.9 H Riboflavin synthase
KMCOHGGH_02138 4.7e-210 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KMCOHGGH_02139 1.7e-49 ypuD
KMCOHGGH_02140 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KMCOHGGH_02141 8.2e-82 ccdC1 O Protein of unknown function (DUF1453)
KMCOHGGH_02142 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KMCOHGGH_02143 6e-155 ypuA S Secreted protein
KMCOHGGH_02144 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KMCOHGGH_02145 1.4e-270 spoVAF EG Stage V sporulation protein AF
KMCOHGGH_02146 1.8e-110 spoVAEA S stage V sporulation protein
KMCOHGGH_02147 3.8e-57 spoVAEB S stage V sporulation protein
KMCOHGGH_02148 9.3e-189 spoVAD I Stage V sporulation protein AD
KMCOHGGH_02149 2.1e-79 spoVAC S stage V sporulation protein AC
KMCOHGGH_02150 3e-60 spoVAB S Stage V sporulation protein AB
KMCOHGGH_02151 3.7e-111 spoVAA S Stage V sporulation protein AA
KMCOHGGH_02152 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMCOHGGH_02153 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KMCOHGGH_02154 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KMCOHGGH_02155 4.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KMCOHGGH_02156 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KMCOHGGH_02157 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KMCOHGGH_02158 5.3e-164 xerD L recombinase XerD
KMCOHGGH_02159 9.2e-36 S Protein of unknown function (DUF4227)
KMCOHGGH_02160 1.9e-80 fur P Belongs to the Fur family
KMCOHGGH_02161 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KMCOHGGH_02163 1.7e-34 yqkK
KMCOHGGH_02164 5.7e-22
KMCOHGGH_02165 7.7e-244 mleA 1.1.1.38 C malic enzyme
KMCOHGGH_02166 9.4e-240 mleN C Na H antiporter
KMCOHGGH_02167 3.7e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KMCOHGGH_02168 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
KMCOHGGH_02169 3e-57 ansR K Transcriptional regulator
KMCOHGGH_02170 1.2e-219 yqxK 3.6.4.12 L DNA helicase
KMCOHGGH_02171 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KMCOHGGH_02173 2.2e-168 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KMCOHGGH_02175 5.1e-178 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KMCOHGGH_02176 3.2e-39 yqkC S Protein of unknown function (DUF2552)
KMCOHGGH_02177 7.7e-61 yqkB S Belongs to the HesB IscA family
KMCOHGGH_02178 4.1e-178 yqkA K GrpB protein
KMCOHGGH_02179 4.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KMCOHGGH_02180 6.6e-89 yqjY K acetyltransferase
KMCOHGGH_02181 2.7e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMCOHGGH_02182 7.6e-58 S YolD-like protein
KMCOHGGH_02184 5.1e-185 yueF S transporter activity
KMCOHGGH_02186 6.6e-74 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMCOHGGH_02187 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
KMCOHGGH_02188 1.9e-258 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KMCOHGGH_02189 4.2e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KMCOHGGH_02190 2.8e-174 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KMCOHGGH_02191 3.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMCOHGGH_02192 7.5e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KMCOHGGH_02193 3e-240 pksG 2.3.3.10 I synthase
KMCOHGGH_02194 9.8e-219 eryK 1.14.13.154 C Cytochrome P450
KMCOHGGH_02195 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KMCOHGGH_02196 0.0 Q Polyketide synthase of type I
KMCOHGGH_02197 0.0 pfaA Q Polyketide synthase of type I
KMCOHGGH_02198 0.0 pksJ Q Polyketide synthase of type I
KMCOHGGH_02199 0.0 Q Polyketide synthase of type I
KMCOHGGH_02200 0.0 1.1.1.320 Q Polyketide synthase of type I
KMCOHGGH_02201 0.0 pksJ Q Polyketide synthase of type I
KMCOHGGH_02202 5.5e-130 IQ reductase
KMCOHGGH_02203 4.1e-248 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMCOHGGH_02206 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KMCOHGGH_02207 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
KMCOHGGH_02208 4.9e-162 K LysR substrate binding domain
KMCOHGGH_02209 3.2e-50 S GlpM protein
KMCOHGGH_02210 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KMCOHGGH_02211 1.3e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KMCOHGGH_02212 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KMCOHGGH_02213 9.5e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KMCOHGGH_02214 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KMCOHGGH_02215 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KMCOHGGH_02216 1.5e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMCOHGGH_02217 2.4e-25 yqzJ
KMCOHGGH_02218 3.5e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KMCOHGGH_02219 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KMCOHGGH_02220 5.7e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KMCOHGGH_02221 2.5e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KMCOHGGH_02223 1.4e-95 yqjB S protein conserved in bacteria
KMCOHGGH_02224 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
KMCOHGGH_02225 1e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KMCOHGGH_02226 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
KMCOHGGH_02227 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
KMCOHGGH_02228 1e-75 yqiW S Belongs to the UPF0403 family
KMCOHGGH_02229 2.7e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KMCOHGGH_02230 2.3e-205 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMCOHGGH_02231 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMCOHGGH_02232 3e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMCOHGGH_02233 7.7e-266 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMCOHGGH_02234 7.5e-208 buk 2.7.2.7 C Belongs to the acetokinase family
KMCOHGGH_02235 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KMCOHGGH_02236 3.1e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KMCOHGGH_02237 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KMCOHGGH_02238 3.2e-34 yqzF S Protein of unknown function (DUF2627)
KMCOHGGH_02239 4.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KMCOHGGH_02240 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KMCOHGGH_02241 1.7e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KMCOHGGH_02242 6.1e-205 mmgC I acyl-CoA dehydrogenase
KMCOHGGH_02243 4.3e-155 hbdA 1.1.1.157 I Dehydrogenase
KMCOHGGH_02244 9.8e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
KMCOHGGH_02245 2.5e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KMCOHGGH_02246 2e-104 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KMCOHGGH_02247 2.5e-17
KMCOHGGH_02248 1.5e-101 ytaF P Probably functions as a manganese efflux pump
KMCOHGGH_02249 1.8e-113 K Protein of unknown function (DUF1232)
KMCOHGGH_02251 3.2e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KMCOHGGH_02254 1.4e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMCOHGGH_02255 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KMCOHGGH_02256 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
KMCOHGGH_02257 1.2e-305 recN L May be involved in recombinational repair of damaged DNA
KMCOHGGH_02258 3.9e-78 argR K Regulates arginine biosynthesis genes
KMCOHGGH_02259 4.3e-155 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KMCOHGGH_02260 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KMCOHGGH_02261 3.6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KMCOHGGH_02262 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KMCOHGGH_02263 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KMCOHGGH_02264 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KMCOHGGH_02265 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KMCOHGGH_02266 8.1e-67 yqhY S protein conserved in bacteria
KMCOHGGH_02267 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KMCOHGGH_02268 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KMCOHGGH_02269 2.5e-62 spoIIIAH S SpoIIIAH-like protein
KMCOHGGH_02270 2.2e-117 spoIIIAG S stage III sporulation protein AG
KMCOHGGH_02271 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KMCOHGGH_02272 6.3e-200 spoIIIAE S stage III sporulation protein AE
KMCOHGGH_02273 2.5e-41 spoIIIAD S Stage III sporulation protein AD
KMCOHGGH_02274 7.6e-29 spoIIIAC S stage III sporulation protein AC
KMCOHGGH_02275 1.7e-85 spoIIIAB S Stage III sporulation protein
KMCOHGGH_02276 4.2e-172 spoIIIAA S stage III sporulation protein AA
KMCOHGGH_02277 1.8e-36 yqhV S Protein of unknown function (DUF2619)
KMCOHGGH_02278 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KMCOHGGH_02279 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KMCOHGGH_02280 3.7e-88 yqhR S Conserved membrane protein YqhR
KMCOHGGH_02281 1e-173 yqhQ S Protein of unknown function (DUF1385)
KMCOHGGH_02282 3.4e-62 yqhP
KMCOHGGH_02283 2e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
KMCOHGGH_02284 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KMCOHGGH_02285 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KMCOHGGH_02286 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
KMCOHGGH_02287 1.5e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KMCOHGGH_02288 4.6e-252 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KMCOHGGH_02289 1.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KMCOHGGH_02290 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KMCOHGGH_02291 3.2e-152 yqhG S Bacterial protein YqhG of unknown function
KMCOHGGH_02292 5.2e-23 sinI S Anti-repressor SinI
KMCOHGGH_02293 7.8e-55 sinR K transcriptional
KMCOHGGH_02294 3.3e-141 tasA S Cell division protein FtsN
KMCOHGGH_02295 1.3e-70 sipW 3.4.21.89 U Signal peptidase
KMCOHGGH_02296 3.8e-122 yqxM
KMCOHGGH_02297 8.3e-54 yqzG S Protein of unknown function (DUF3889)
KMCOHGGH_02298 2.3e-26 yqzE S YqzE-like protein
KMCOHGGH_02299 4.3e-62 S ComG operon protein 7
KMCOHGGH_02300 9.6e-65 comGF U Putative Competence protein ComGF
KMCOHGGH_02301 7.6e-20 comGE
KMCOHGGH_02302 6.2e-73 gspH NU Tfp pilus assembly protein FimT
KMCOHGGH_02303 1e-41 comGC U Required for transformation and DNA binding
KMCOHGGH_02304 1.7e-182 comGB NU COG1459 Type II secretory pathway, component PulF
KMCOHGGH_02305 6.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KMCOHGGH_02306 4.1e-186 corA P Mg2 transporter protein
KMCOHGGH_02307 1.6e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KMCOHGGH_02308 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMCOHGGH_02310 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
KMCOHGGH_02311 3.1e-37 yqgY S Protein of unknown function (DUF2626)
KMCOHGGH_02312 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KMCOHGGH_02313 5.4e-20 yqgW S Protein of unknown function (DUF2759)
KMCOHGGH_02314 6.9e-50 yqgV S Thiamine-binding protein
KMCOHGGH_02315 1.7e-198 yqgU
KMCOHGGH_02316 8.4e-223 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KMCOHGGH_02317 2.2e-179 glcK 2.7.1.2 G Glucokinase
KMCOHGGH_02318 4.6e-223 nhaC C Na H antiporter
KMCOHGGH_02319 4e-07 yqgO
KMCOHGGH_02320 1e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KMCOHGGH_02321 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KMCOHGGH_02322 1.2e-50 yqzD
KMCOHGGH_02323 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KMCOHGGH_02324 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KMCOHGGH_02325 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KMCOHGGH_02326 1.8e-156 pstA P Phosphate transport system permease
KMCOHGGH_02327 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
KMCOHGGH_02328 1.7e-157 pstS P Phosphate
KMCOHGGH_02329 0.0 pbpA 3.4.16.4 M penicillin-binding protein
KMCOHGGH_02330 4.5e-228 yqgE EGP Major facilitator superfamily
KMCOHGGH_02331 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KMCOHGGH_02332 6e-77 yqgC S protein conserved in bacteria
KMCOHGGH_02333 1.2e-127 yqgB S Protein of unknown function (DUF1189)
KMCOHGGH_02334 3.7e-48 yqfZ M LysM domain
KMCOHGGH_02335 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KMCOHGGH_02336 2.3e-52 yqfX S membrane
KMCOHGGH_02337 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KMCOHGGH_02338 2.9e-72 zur P Belongs to the Fur family
KMCOHGGH_02339 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KMCOHGGH_02340 9.3e-37 yqfT S Protein of unknown function (DUF2624)
KMCOHGGH_02341 1.3e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KMCOHGGH_02342 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KMCOHGGH_02343 1.4e-50 yqfQ S YqfQ-like protein
KMCOHGGH_02344 4.9e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KMCOHGGH_02345 4.3e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KMCOHGGH_02346 5.8e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
KMCOHGGH_02347 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
KMCOHGGH_02348 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KMCOHGGH_02349 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KMCOHGGH_02350 6.1e-88 yaiI S Belongs to the UPF0178 family
KMCOHGGH_02351 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KMCOHGGH_02352 4.5e-112 ccpN K CBS domain
KMCOHGGH_02353 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KMCOHGGH_02354 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KMCOHGGH_02355 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
KMCOHGGH_02356 1.8e-16 S YqzL-like protein
KMCOHGGH_02357 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KMCOHGGH_02358 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KMCOHGGH_02359 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KMCOHGGH_02360 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KMCOHGGH_02361 0.0 yqfF S membrane-associated HD superfamily hydrolase
KMCOHGGH_02362 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
KMCOHGGH_02363 4.2e-217 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KMCOHGGH_02364 9.3e-46 yqfC S sporulation protein YqfC
KMCOHGGH_02365 3.4e-55 yqfB
KMCOHGGH_02366 1.6e-121 yqfA S UPF0365 protein
KMCOHGGH_02367 3.4e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KMCOHGGH_02368 1.2e-68 yqeY S Yqey-like protein
KMCOHGGH_02369 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KMCOHGGH_02370 1e-157 yqeW P COG1283 Na phosphate symporter
KMCOHGGH_02371 1.2e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KMCOHGGH_02372 7.9e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KMCOHGGH_02373 4.6e-174 prmA J Methylates ribosomal protein L11
KMCOHGGH_02374 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KMCOHGGH_02375 0.0 dnaK O Heat shock 70 kDa protein
KMCOHGGH_02376 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KMCOHGGH_02377 2.3e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KMCOHGGH_02378 6.3e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
KMCOHGGH_02379 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KMCOHGGH_02380 3.8e-54 yqxA S Protein of unknown function (DUF3679)
KMCOHGGH_02381 1.6e-219 spoIIP M stage II sporulation protein P
KMCOHGGH_02382 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KMCOHGGH_02383 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
KMCOHGGH_02384 2.5e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
KMCOHGGH_02385 0.0 comEC S Competence protein ComEC
KMCOHGGH_02386 1e-104 comEB 3.5.4.12 F ComE operon protein 2
KMCOHGGH_02387 1.2e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KMCOHGGH_02388 6.5e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMCOHGGH_02389 1.1e-138 yqeM Q Methyltransferase
KMCOHGGH_02390 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KMCOHGGH_02391 5.6e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KMCOHGGH_02392 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KMCOHGGH_02393 1.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KMCOHGGH_02394 2.1e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KMCOHGGH_02395 1.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KMCOHGGH_02396 2e-94 yqeG S hydrolase of the HAD superfamily
KMCOHGGH_02398 7.7e-140 yqeF E GDSL-like Lipase/Acylhydrolase
KMCOHGGH_02399 5.8e-140 3.5.1.104 G Polysaccharide deacetylase
KMCOHGGH_02400 9.4e-107 yqeD S SNARE associated Golgi protein
KMCOHGGH_02401 8.5e-35 2.3.1.57 K Acetyltransferase (GNAT) domain
KMCOHGGH_02402 5e-216 EGP Major facilitator Superfamily
KMCOHGGH_02403 4e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMCOHGGH_02404 2.2e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
KMCOHGGH_02405 8e-91 K Transcriptional regulator PadR-like family
KMCOHGGH_02406 1.2e-147 ydeE K AraC family transcriptional regulator
KMCOHGGH_02407 3.9e-21 leuB1 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
KMCOHGGH_02408 4e-98 adk 2.7.4.3 F adenylate kinase activity
KMCOHGGH_02409 5.3e-219 tetL EGP Major facilitator Superfamily
KMCOHGGH_02410 4.4e-81 yyaR K Acetyltransferase (GNAT) domain
KMCOHGGH_02411 1.1e-92 yrdA S DinB family
KMCOHGGH_02413 9.1e-147 S hydrolase
KMCOHGGH_02414 5.6e-144 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
KMCOHGGH_02415 2.3e-128 glvR K Helix-turn-helix domain, rpiR family
KMCOHGGH_02416 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
KMCOHGGH_02417 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KMCOHGGH_02418 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KMCOHGGH_02419 2.1e-184 romA S Beta-lactamase superfamily domain
KMCOHGGH_02420 2.3e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KMCOHGGH_02421 2.4e-164 yybE K Transcriptional regulator
KMCOHGGH_02422 5.5e-212 ynfM EGP Major facilitator Superfamily
KMCOHGGH_02423 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KMCOHGGH_02424 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KMCOHGGH_02425 3.9e-93 yrhH Q methyltransferase
KMCOHGGH_02427 8e-143 focA P Formate nitrite
KMCOHGGH_02428 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
KMCOHGGH_02429 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
KMCOHGGH_02430 7e-81 yrhD S Protein of unknown function (DUF1641)
KMCOHGGH_02431 1.8e-34 yrhC S YrhC-like protein
KMCOHGGH_02432 1.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KMCOHGGH_02433 4.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KMCOHGGH_02434 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KMCOHGGH_02435 7.1e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KMCOHGGH_02436 1.6e-26 yrzA S Protein of unknown function (DUF2536)
KMCOHGGH_02437 3.1e-69 yrrS S Protein of unknown function (DUF1510)
KMCOHGGH_02438 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KMCOHGGH_02439 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KMCOHGGH_02440 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
KMCOHGGH_02441 1.6e-246 yegQ O COG0826 Collagenase and related proteases
KMCOHGGH_02442 1.7e-173 yegQ O Peptidase U32
KMCOHGGH_02443 2.1e-117 yrrM 2.1.1.104 S O-methyltransferase
KMCOHGGH_02444 9.7e-192 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KMCOHGGH_02445 7.1e-46 yrzB S Belongs to the UPF0473 family
KMCOHGGH_02446 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KMCOHGGH_02447 8.5e-41 yrzL S Belongs to the UPF0297 family
KMCOHGGH_02448 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KMCOHGGH_02449 5.2e-166 yrrI S AI-2E family transporter
KMCOHGGH_02450 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KMCOHGGH_02451 3.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
KMCOHGGH_02452 1.2e-109 gluC P ABC transporter
KMCOHGGH_02453 1.3e-106 glnP P ABC transporter
KMCOHGGH_02454 2.1e-08 S Protein of unknown function (DUF3918)
KMCOHGGH_02455 2.9e-30 yrzR
KMCOHGGH_02456 1.8e-83 yrrD S protein conserved in bacteria
KMCOHGGH_02457 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KMCOHGGH_02458 1.7e-18 S COG0457 FOG TPR repeat
KMCOHGGH_02459 5.4e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KMCOHGGH_02460 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
KMCOHGGH_02461 7.8e-64 cymR K Transcriptional regulator
KMCOHGGH_02462 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KMCOHGGH_02463 3.7e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KMCOHGGH_02464 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KMCOHGGH_02465 2.8e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
KMCOHGGH_02468 1.1e-278 lytH 3.5.1.28 M COG3103 SH3 domain protein
KMCOHGGH_02469 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KMCOHGGH_02470 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KMCOHGGH_02471 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KMCOHGGH_02472 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KMCOHGGH_02473 3.3e-47 yrvD S Lipopolysaccharide assembly protein A domain
KMCOHGGH_02474 1.5e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KMCOHGGH_02475 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KMCOHGGH_02476 1.3e-50 yrzD S Post-transcriptional regulator
KMCOHGGH_02477 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMCOHGGH_02478 9.5e-110 yrbG S membrane
KMCOHGGH_02479 2.4e-60 yrzE S Protein of unknown function (DUF3792)
KMCOHGGH_02480 5.6e-37 yajC U Preprotein translocase subunit YajC
KMCOHGGH_02481 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KMCOHGGH_02482 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KMCOHGGH_02483 1.6e-20 yrzS S Protein of unknown function (DUF2905)
KMCOHGGH_02484 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KMCOHGGH_02485 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KMCOHGGH_02486 1.4e-92 bofC S BofC C-terminal domain
KMCOHGGH_02488 2.7e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMCOHGGH_02489 4.6e-147 safA M spore coat assembly protein SafA
KMCOHGGH_02490 4.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KMCOHGGH_02491 1.8e-153 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KMCOHGGH_02492 4.5e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KMCOHGGH_02493 1.7e-223 nifS 2.8.1.7 E Cysteine desulfurase
KMCOHGGH_02494 1.1e-95 niaR S small molecule binding protein (contains 3H domain)
KMCOHGGH_02495 3.5e-160 pheA 4.2.1.51 E Prephenate dehydratase
KMCOHGGH_02496 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KMCOHGGH_02497 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KMCOHGGH_02498 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KMCOHGGH_02499 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KMCOHGGH_02500 3.2e-56 ysxB J ribosomal protein
KMCOHGGH_02501 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
KMCOHGGH_02502 1.2e-160 spoIVFB S Stage IV sporulation protein
KMCOHGGH_02503 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KMCOHGGH_02504 2.3e-142 minD D Belongs to the ParA family
KMCOHGGH_02505 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KMCOHGGH_02506 1.4e-84 mreD M shape-determining protein
KMCOHGGH_02507 1.2e-157 mreC M Involved in formation and maintenance of cell shape
KMCOHGGH_02508 4e-184 mreB D Rod shape-determining protein MreB
KMCOHGGH_02509 1.8e-127 radC E Belongs to the UPF0758 family
KMCOHGGH_02510 1.2e-100 maf D septum formation protein Maf
KMCOHGGH_02511 2.8e-137 spoIIB S Sporulation related domain
KMCOHGGH_02512 1e-131 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KMCOHGGH_02513 3.9e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KMCOHGGH_02514 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KMCOHGGH_02515 2.1e-25
KMCOHGGH_02516 2.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KMCOHGGH_02517 1.2e-218 spoVID M stage VI sporulation protein D
KMCOHGGH_02518 6.8e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KMCOHGGH_02519 1e-184 hemB 4.2.1.24 H Belongs to the ALAD family
KMCOHGGH_02520 2.9e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KMCOHGGH_02521 2.1e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KMCOHGGH_02522 3.6e-146 hemX O cytochrome C
KMCOHGGH_02523 1.2e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KMCOHGGH_02524 8.5e-87 ysxD
KMCOHGGH_02525 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
KMCOHGGH_02526 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KMCOHGGH_02527 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KMCOHGGH_02528 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KMCOHGGH_02529 3.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KMCOHGGH_02530 9.2e-189 ysoA H Tetratricopeptide repeat
KMCOHGGH_02531 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KMCOHGGH_02532 6.3e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KMCOHGGH_02533 5.3e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KMCOHGGH_02534 1.4e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KMCOHGGH_02535 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KMCOHGGH_02536 5.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
KMCOHGGH_02537 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KMCOHGGH_02542 7e-92 ysnB S Phosphoesterase
KMCOHGGH_02543 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KMCOHGGH_02544 5.8e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KMCOHGGH_02545 2.4e-198 gerM S COG5401 Spore germination protein
KMCOHGGH_02546 7.8e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KMCOHGGH_02547 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KMCOHGGH_02548 2e-30 gerE K Transcriptional regulator
KMCOHGGH_02549 3.2e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KMCOHGGH_02550 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KMCOHGGH_02551 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KMCOHGGH_02552 4.8e-108 sdhC C succinate dehydrogenase
KMCOHGGH_02553 7.7e-79 yslB S Protein of unknown function (DUF2507)
KMCOHGGH_02554 4.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KMCOHGGH_02555 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KMCOHGGH_02556 2.5e-52 trxA O Belongs to the thioredoxin family
KMCOHGGH_02557 5.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KMCOHGGH_02558 4.2e-178 etfA C Electron transfer flavoprotein
KMCOHGGH_02559 2e-138 etfB C Electron transfer flavoprotein
KMCOHGGH_02560 1.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KMCOHGGH_02561 9.2e-104 fadR K Transcriptional regulator
KMCOHGGH_02562 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMCOHGGH_02563 6.6e-122 ywbB S Protein of unknown function (DUF2711)
KMCOHGGH_02564 4.7e-67 yshE S membrane
KMCOHGGH_02565 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KMCOHGGH_02566 0.0 polX L COG1796 DNA polymerase IV (family X)
KMCOHGGH_02567 3.6e-83 cvpA S membrane protein, required for colicin V production
KMCOHGGH_02568 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KMCOHGGH_02569 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMCOHGGH_02570 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KMCOHGGH_02571 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KMCOHGGH_02572 1.4e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMCOHGGH_02573 2e-32 sspI S Belongs to the SspI family
KMCOHGGH_02574 2.2e-204 ysfB KT regulator
KMCOHGGH_02575 2.4e-259 glcD 1.1.3.15 C FAD binding domain
KMCOHGGH_02576 9.8e-255 glcF C Glycolate oxidase
KMCOHGGH_02577 0.0 cstA T Carbon starvation protein
KMCOHGGH_02578 1.1e-299 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KMCOHGGH_02579 1.2e-144 araQ G transport system permease
KMCOHGGH_02580 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
KMCOHGGH_02581 7.6e-252 araN G carbohydrate transport
KMCOHGGH_02582 1.6e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KMCOHGGH_02583 3.2e-142 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KMCOHGGH_02584 1.6e-131 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KMCOHGGH_02585 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KMCOHGGH_02586 3.1e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KMCOHGGH_02587 3e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KMCOHGGH_02588 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
KMCOHGGH_02589 9.2e-68 ysdB S Sigma-w pathway protein YsdB
KMCOHGGH_02590 7e-43 ysdA S Membrane
KMCOHGGH_02591 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KMCOHGGH_02592 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KMCOHGGH_02593 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KMCOHGGH_02594 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KMCOHGGH_02595 3.1e-40 lrgA S effector of murein hydrolase LrgA
KMCOHGGH_02596 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
KMCOHGGH_02597 0.0 lytS 2.7.13.3 T Histidine kinase
KMCOHGGH_02598 3.5e-151 ysaA S HAD-hyrolase-like
KMCOHGGH_02599 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KMCOHGGH_02600 8.8e-153 ytxC S YtxC-like family
KMCOHGGH_02601 2.7e-109 ytxB S SNARE associated Golgi protein
KMCOHGGH_02602 9.5e-172 dnaI L Primosomal protein DnaI
KMCOHGGH_02603 1.3e-257 dnaB L Membrane attachment protein
KMCOHGGH_02604 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KMCOHGGH_02605 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KMCOHGGH_02606 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KMCOHGGH_02607 2e-67 ytcD K Transcriptional regulator
KMCOHGGH_02608 9.9e-206 ytbD EGP Major facilitator Superfamily
KMCOHGGH_02609 1.5e-160 ytbE S reductase
KMCOHGGH_02610 1.3e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KMCOHGGH_02611 2.1e-106 ytaF P Probably functions as a manganese efflux pump
KMCOHGGH_02612 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KMCOHGGH_02613 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KMCOHGGH_02614 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KMCOHGGH_02615 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_02616 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KMCOHGGH_02617 3.1e-242 icd 1.1.1.42 C isocitrate
KMCOHGGH_02618 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KMCOHGGH_02619 4.2e-47 yjdF S Protein of unknown function (DUF2992)
KMCOHGGH_02620 1.5e-72 yeaL S membrane
KMCOHGGH_02621 1.1e-193 ytvI S sporulation integral membrane protein YtvI
KMCOHGGH_02622 7.9e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KMCOHGGH_02623 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KMCOHGGH_02624 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KMCOHGGH_02625 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KMCOHGGH_02626 5.1e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KMCOHGGH_02627 3.7e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
KMCOHGGH_02628 0.0 dnaE 2.7.7.7 L DNA polymerase
KMCOHGGH_02629 3.2e-56 ytrH S Sporulation protein YtrH
KMCOHGGH_02630 5.1e-87 ytrI
KMCOHGGH_02631 4.4e-23
KMCOHGGH_02632 4.6e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KMCOHGGH_02633 2.4e-47 ytpI S YtpI-like protein
KMCOHGGH_02634 2.8e-238 ytoI K transcriptional regulator containing CBS domains
KMCOHGGH_02635 2.5e-129 ytkL S Belongs to the UPF0173 family
KMCOHGGH_02636 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMCOHGGH_02638 7e-264 argH 4.3.2.1 E argininosuccinate lyase
KMCOHGGH_02639 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KMCOHGGH_02640 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KMCOHGGH_02641 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KMCOHGGH_02642 1.4e-184 ytxK 2.1.1.72 L DNA methylase
KMCOHGGH_02643 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KMCOHGGH_02644 1.6e-60 ytfJ S Sporulation protein YtfJ
KMCOHGGH_02645 3.8e-109 ytfI S Protein of unknown function (DUF2953)
KMCOHGGH_02646 4.5e-88 yteJ S RDD family
KMCOHGGH_02647 2.4e-181 sppA OU signal peptide peptidase SppA
KMCOHGGH_02648 6.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KMCOHGGH_02649 0.0 ytcJ S amidohydrolase
KMCOHGGH_02650 8.5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KMCOHGGH_02651 3.9e-31 sspB S spore protein
KMCOHGGH_02652 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KMCOHGGH_02653 4.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
KMCOHGGH_02654 6.9e-240 braB E Component of the transport system for branched-chain amino acids
KMCOHGGH_02655 7.3e-263 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KMCOHGGH_02656 4.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KMCOHGGH_02657 7.7e-109 yttP K Transcriptional regulator
KMCOHGGH_02658 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
KMCOHGGH_02659 2.7e-284 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KMCOHGGH_02660 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KMCOHGGH_02661 3.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KMCOHGGH_02662 2.6e-49 yokH G SMI1 / KNR4 family
KMCOHGGH_02665 1.1e-58 UW Hep Hag repeat protein
KMCOHGGH_02666 2e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KMCOHGGH_02667 7.3e-09
KMCOHGGH_02668 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
KMCOHGGH_02670 5.9e-140 E GDSL-like Lipase/Acylhydrolase family
KMCOHGGH_02671 1.9e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMCOHGGH_02672 4.4e-149 K Transcriptional regulator
KMCOHGGH_02673 1.5e-124 azlC E AzlC protein
KMCOHGGH_02674 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
KMCOHGGH_02675 7.9e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KMCOHGGH_02676 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KMCOHGGH_02677 8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KMCOHGGH_02678 7.1e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
KMCOHGGH_02679 2.3e-231 acuC BQ histone deacetylase
KMCOHGGH_02680 1.4e-119 motS N Flagellar motor protein
KMCOHGGH_02681 5.1e-145 motA N flagellar motor
KMCOHGGH_02682 6.4e-182 ccpA K catabolite control protein A
KMCOHGGH_02683 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KMCOHGGH_02684 2.9e-43 ytxJ O Protein of unknown function (DUF2847)
KMCOHGGH_02685 1.7e-16 ytxH S COG4980 Gas vesicle protein
KMCOHGGH_02686 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KMCOHGGH_02687 4.2e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KMCOHGGH_02688 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KMCOHGGH_02689 2e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KMCOHGGH_02690 3.7e-148 ytpQ S Belongs to the UPF0354 family
KMCOHGGH_02691 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KMCOHGGH_02692 4.5e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KMCOHGGH_02693 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KMCOHGGH_02694 1.7e-51 ytzB S small secreted protein
KMCOHGGH_02695 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KMCOHGGH_02696 7.1e-166 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KMCOHGGH_02697 4e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KMCOHGGH_02698 3.5e-45 ytzH S YtzH-like protein
KMCOHGGH_02699 1.8e-155 ytmP 2.7.1.89 M Phosphotransferase
KMCOHGGH_02700 8e-179 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KMCOHGGH_02701 2.2e-168 ytlQ
KMCOHGGH_02702 1.8e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KMCOHGGH_02703 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KMCOHGGH_02704 1.9e-269 pepV 3.5.1.18 E Dipeptidase
KMCOHGGH_02705 9.1e-229 pbuO S permease
KMCOHGGH_02706 1.1e-217 ythQ U Bacterial ABC transporter protein EcsB
KMCOHGGH_02707 4.9e-128 ythP V ABC transporter
KMCOHGGH_02708 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KMCOHGGH_02709 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KMCOHGGH_02710 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMCOHGGH_02711 3.3e-236 ytfP S HI0933-like protein
KMCOHGGH_02712 5.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KMCOHGGH_02713 9e-26 yteV S Sporulation protein Cse60
KMCOHGGH_02714 2.6e-186 msmR K Transcriptional regulator
KMCOHGGH_02715 1.2e-246 msmE G Bacterial extracellular solute-binding protein
KMCOHGGH_02716 4.8e-168 amyD G Binding-protein-dependent transport system inner membrane component
KMCOHGGH_02717 1.4e-142 amyC P ABC transporter (permease)
KMCOHGGH_02718 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KMCOHGGH_02719 2.4e-86 M Acetyltransferase (GNAT) domain
KMCOHGGH_02720 5.6e-52 ytwF P Sulfurtransferase
KMCOHGGH_02721 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KMCOHGGH_02722 6.1e-52 ytvB S Protein of unknown function (DUF4257)
KMCOHGGH_02723 6.6e-140 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KMCOHGGH_02724 7.3e-209 yttB EGP Major facilitator Superfamily
KMCOHGGH_02725 2.2e-128 ywaF S Integral membrane protein
KMCOHGGH_02726 0.0 bceB V ABC transporter (permease)
KMCOHGGH_02727 9.8e-135 bceA V ABC transporter, ATP-binding protein
KMCOHGGH_02728 1.1e-170 T PhoQ Sensor
KMCOHGGH_02729 8.2e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_02730 4.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KMCOHGGH_02731 1.3e-125 ytrE V ABC transporter, ATP-binding protein
KMCOHGGH_02732 8.8e-160
KMCOHGGH_02733 5.6e-145 P ABC-2 family transporter protein
KMCOHGGH_02734 3.6e-169 S ABC-2 family transporter protein
KMCOHGGH_02735 1.9e-161 ytrB P abc transporter atp-binding protein
KMCOHGGH_02736 3.9e-66 ytrA K GntR family transcriptional regulator
KMCOHGGH_02737 7.4e-40 ytzC S Protein of unknown function (DUF2524)
KMCOHGGH_02738 1.2e-192 K helix_turn_helix, Arsenical Resistance Operon Repressor
KMCOHGGH_02739 3.5e-286 norB EGP COG0477 Permeases of the major facilitator superfamily
KMCOHGGH_02740 2.1e-190 yhcC S Fe-S oxidoreductase
KMCOHGGH_02741 6.7e-107 ytqB J Putative rRNA methylase
KMCOHGGH_02743 8.6e-145 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
KMCOHGGH_02744 9.9e-213 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KMCOHGGH_02745 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
KMCOHGGH_02746 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KMCOHGGH_02747 1.9e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KMCOHGGH_02748 0.0 asnB 6.3.5.4 E Asparagine synthase
KMCOHGGH_02749 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KMCOHGGH_02750 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KMCOHGGH_02751 1.6e-38 ytmB S Protein of unknown function (DUF2584)
KMCOHGGH_02752 6.1e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KMCOHGGH_02753 3.3e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KMCOHGGH_02754 2.1e-143 ytlC P ABC transporter
KMCOHGGH_02755 4.6e-130 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KMCOHGGH_02756 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KMCOHGGH_02757 1.7e-61 ytkC S Bacteriophage holin family
KMCOHGGH_02758 1.6e-76 dps P Belongs to the Dps family
KMCOHGGH_02760 1.8e-75 ytkA S YtkA-like
KMCOHGGH_02761 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KMCOHGGH_02762 6.2e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KMCOHGGH_02763 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KMCOHGGH_02764 3e-40 rpmE2 J Ribosomal protein L31
KMCOHGGH_02765 7.6e-239 cydA 1.10.3.14 C oxidase, subunit
KMCOHGGH_02766 1.7e-185 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KMCOHGGH_02767 2.3e-24 S Domain of Unknown Function (DUF1540)
KMCOHGGH_02768 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KMCOHGGH_02769 2.9e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KMCOHGGH_02770 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KMCOHGGH_02771 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KMCOHGGH_02772 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KMCOHGGH_02773 3.2e-272 menF 5.4.4.2 HQ Isochorismate synthase
KMCOHGGH_02774 2e-132 dksA T COG1734 DnaK suppressor protein
KMCOHGGH_02775 1.5e-77 tspO T membrane
KMCOHGGH_02776 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_02777 1.1e-40 L transposase activity
KMCOHGGH_02786 7.8e-08
KMCOHGGH_02787 1.3e-09
KMCOHGGH_02794 1.6e-08
KMCOHGGH_02799 3.4e-39 S COG NOG14552 non supervised orthologous group
KMCOHGGH_02800 9.7e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
KMCOHGGH_02801 5.9e-179 yuaG 3.4.21.72 S protein conserved in bacteria
KMCOHGGH_02802 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KMCOHGGH_02803 2.2e-82 yuaE S DinB superfamily
KMCOHGGH_02804 2.5e-109 yuaD S MOSC domain
KMCOHGGH_02805 1.6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
KMCOHGGH_02806 7.2e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KMCOHGGH_02807 2.7e-97 yuaC K Belongs to the GbsR family
KMCOHGGH_02808 7.9e-94 yuaB
KMCOHGGH_02809 7.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
KMCOHGGH_02810 6.7e-148 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KMCOHGGH_02811 2e-219 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KMCOHGGH_02812 7.3e-123 G Cupin
KMCOHGGH_02813 1.8e-38 yjcN
KMCOHGGH_02817 1.9e-115 S Aspartate phosphatase response regulator
KMCOHGGH_02818 2.6e-12
KMCOHGGH_02821 3.4e-51
KMCOHGGH_02822 1.6e-25 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KMCOHGGH_02823 1.8e-19 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KMCOHGGH_02824 3.2e-11
KMCOHGGH_02826 5e-52 gepA S Protein of unknown function (DUF4065)
KMCOHGGH_02827 1.9e-192 M nucleic acid phosphodiester bond hydrolysis
KMCOHGGH_02828 2.2e-30 S SMI1-KNR4 cell-wall
KMCOHGGH_02829 5e-123 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KMCOHGGH_02830 2.9e-59 S Pfam:Phage_holin_4_1
KMCOHGGH_02834 4.4e-200 sidC L Phage minor structural protein
KMCOHGGH_02835 1e-46
KMCOHGGH_02836 1.3e-123
KMCOHGGH_02838 3.3e-25 S Phage tail assembly chaperone protein, TAC
KMCOHGGH_02839 8.2e-32 N domain, Protein
KMCOHGGH_02840 7.7e-30 S Protein of unknown function (DUF3168)
KMCOHGGH_02841 3.6e-38 S Bacteriophage HK97-gp10, putative tail-component
KMCOHGGH_02842 2.8e-28 S Phage head-tail joining protein
KMCOHGGH_02843 3e-37 S Phage gp6-like head-tail connector protein
KMCOHGGH_02846 9.8e-145 S Phage capsid family
KMCOHGGH_02847 2.7e-55 S Domain of unknown function (DUF4355)
KMCOHGGH_02848 2.5e-92 S Phage Mu protein F like protein
KMCOHGGH_02849 2.6e-197 S Phage portal protein, SPP1 Gp6-like
KMCOHGGH_02850 2e-185 ps334 S Terminase-like family
KMCOHGGH_02851 2.2e-70 yqaS L DNA packaging
KMCOHGGH_02852 6.8e-46 L Transposase
KMCOHGGH_02855 4.4e-86 V restriction endodeoxyribonuclease activity
KMCOHGGH_02860 5e-17 yqaO S Phage-like element PBSX protein XtrA
KMCOHGGH_02861 1e-86 xkdC L IstB-like ATP binding protein
KMCOHGGH_02862 3.7e-75 3.1.3.16 L DnaD domain protein
KMCOHGGH_02864 9.9e-69 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
KMCOHGGH_02865 7.6e-97
KMCOHGGH_02869 4.2e-85
KMCOHGGH_02870 1.1e-45 S Phage regulatory protein Rha (Phage_pRha)
KMCOHGGH_02871 3.4e-15 S Helix-turn-helix domain
KMCOHGGH_02872 9.4e-17 K Helix-turn-helix domain
KMCOHGGH_02873 8.3e-18 xre K Helix-turn-helix XRE-family like proteins
KMCOHGGH_02874 1.3e-25 S Short C-terminal domain
KMCOHGGH_02875 4.4e-49 xkdA E IrrE N-terminal-like domain
KMCOHGGH_02876 1.9e-167 L Belongs to the 'phage' integrase family
KMCOHGGH_02878 3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KMCOHGGH_02879 9e-196 yubA S transporter activity
KMCOHGGH_02880 2.1e-185 ygjR S Oxidoreductase
KMCOHGGH_02881 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KMCOHGGH_02882 8.2e-237 mcpA NT chemotaxis protein
KMCOHGGH_02883 3.2e-225 mcpA NT chemotaxis protein
KMCOHGGH_02884 5.1e-239 mcpA NT chemotaxis protein
KMCOHGGH_02885 1.5e-219 mcpA NT chemotaxis protein
KMCOHGGH_02886 1.3e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KMCOHGGH_02887 4.8e-41
KMCOHGGH_02888 4.3e-189 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KMCOHGGH_02889 1.2e-76 yugU S Uncharacterised protein family UPF0047
KMCOHGGH_02890 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KMCOHGGH_02891 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KMCOHGGH_02892 8.3e-117 yugP S Zn-dependent protease
KMCOHGGH_02893 9e-18
KMCOHGGH_02894 3.9e-27 mstX S Membrane-integrating protein Mistic
KMCOHGGH_02895 1.8e-181 yugO P COG1226 Kef-type K transport systems
KMCOHGGH_02896 1.3e-72 yugN S YugN-like family
KMCOHGGH_02898 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
KMCOHGGH_02900 1.5e-95 S NADPH-dependent FMN reductase
KMCOHGGH_02901 4.2e-118 ycaC Q Isochorismatase family
KMCOHGGH_02902 2.1e-229 yugK C Dehydrogenase
KMCOHGGH_02903 1.7e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KMCOHGGH_02904 1.8e-34 yuzA S Domain of unknown function (DUF378)
KMCOHGGH_02905 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KMCOHGGH_02906 7.2e-209 yugH 2.6.1.1 E Aminotransferase
KMCOHGGH_02907 2e-83 alaR K Transcriptional regulator
KMCOHGGH_02908 1.1e-155 yugF I Hydrolase
KMCOHGGH_02909 1.4e-40 yugE S Domain of unknown function (DUF1871)
KMCOHGGH_02910 3.2e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KMCOHGGH_02911 1.1e-229 T PhoQ Sensor
KMCOHGGH_02912 6.9e-68 kapB G Kinase associated protein B
KMCOHGGH_02913 5.3e-118 kapD L the KinA pathway to sporulation
KMCOHGGH_02914 1.5e-185 yuxJ EGP Major facilitator Superfamily
KMCOHGGH_02915 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KMCOHGGH_02916 3.8e-72 yuxK S protein conserved in bacteria
KMCOHGGH_02917 9.3e-74 yufK S Family of unknown function (DUF5366)
KMCOHGGH_02918 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KMCOHGGH_02919 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
KMCOHGGH_02920 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KMCOHGGH_02921 3.3e-286 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KMCOHGGH_02922 1.1e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
KMCOHGGH_02923 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
KMCOHGGH_02924 1.8e-12
KMCOHGGH_02925 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KMCOHGGH_02926 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMCOHGGH_02927 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMCOHGGH_02928 1.5e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMCOHGGH_02929 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMCOHGGH_02930 1.2e-37 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMCOHGGH_02931 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KMCOHGGH_02932 2.1e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
KMCOHGGH_02933 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMCOHGGH_02934 4.2e-264 comP 2.7.13.3 T Histidine kinase
KMCOHGGH_02935 1.2e-27 comP 2.7.13.3 T Histidine kinase
KMCOHGGH_02937 2.1e-94 comQ H Polyprenyl synthetase
KMCOHGGH_02939 8.9e-51 yuzC
KMCOHGGH_02940 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KMCOHGGH_02941 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KMCOHGGH_02942 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
KMCOHGGH_02943 7.2e-68 yueI S Protein of unknown function (DUF1694)
KMCOHGGH_02944 8.2e-38 yueH S YueH-like protein
KMCOHGGH_02945 6.4e-34 yueG S Spore germination protein gerPA/gerPF
KMCOHGGH_02946 2.5e-187 yueF S transporter activity
KMCOHGGH_02947 1.6e-22 S Protein of unknown function (DUF2642)
KMCOHGGH_02948 6.3e-96 yueE S phosphohydrolase
KMCOHGGH_02949 4.9e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMCOHGGH_02950 7.7e-77 yueC S Family of unknown function (DUF5383)
KMCOHGGH_02951 0.0 esaA S type VII secretion protein EsaA
KMCOHGGH_02952 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KMCOHGGH_02953 6.2e-206 essB S WXG100 protein secretion system (Wss), protein YukC
KMCOHGGH_02954 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
KMCOHGGH_02955 3.3e-46 esxA S Belongs to the WXG100 family
KMCOHGGH_02956 1.5e-228 yukF QT Transcriptional regulator
KMCOHGGH_02957 3e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KMCOHGGH_02958 1.4e-132 yukJ S Uncharacterized conserved protein (DUF2278)
KMCOHGGH_02959 1.3e-34 mbtH S MbtH-like protein
KMCOHGGH_02960 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_02961 1.2e-174 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KMCOHGGH_02962 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KMCOHGGH_02963 5.6e-225 entC 5.4.4.2 HQ Isochorismate synthase
KMCOHGGH_02964 6.6e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMCOHGGH_02965 7.3e-166 besA S Putative esterase
KMCOHGGH_02966 1.2e-119 yuiH S Oxidoreductase molybdopterin binding domain
KMCOHGGH_02967 1.1e-101 bioY S Biotin biosynthesis protein
KMCOHGGH_02968 1.2e-207 yuiF S antiporter
KMCOHGGH_02969 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KMCOHGGH_02970 3.5e-77 yuiD S protein conserved in bacteria
KMCOHGGH_02971 9.3e-118 yuiC S protein conserved in bacteria
KMCOHGGH_02972 9.9e-28 yuiB S Putative membrane protein
KMCOHGGH_02973 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
KMCOHGGH_02974 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
KMCOHGGH_02976 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KMCOHGGH_02977 4.8e-29
KMCOHGGH_02978 7e-71 CP Membrane
KMCOHGGH_02979 2.1e-123 V ABC transporter
KMCOHGGH_02981 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
KMCOHGGH_02983 1.7e-91 rimJ 2.3.1.128 J Alanine acetyltransferase
KMCOHGGH_02984 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KMCOHGGH_02985 2.4e-62 erpA S Belongs to the HesB IscA family
KMCOHGGH_02986 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KMCOHGGH_02987 3.8e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMCOHGGH_02988 2.4e-39 yuzB S Belongs to the UPF0349 family
KMCOHGGH_02989 1.2e-207 yutJ 1.6.99.3 C NADH dehydrogenase
KMCOHGGH_02990 1.7e-54 yuzD S protein conserved in bacteria
KMCOHGGH_02991 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KMCOHGGH_02992 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KMCOHGGH_02993 8.9e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KMCOHGGH_02994 4e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KMCOHGGH_02995 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
KMCOHGGH_02996 3.2e-197 yutH S Spore coat protein
KMCOHGGH_02997 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KMCOHGGH_02998 8.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KMCOHGGH_02999 9.5e-74 yutE S Protein of unknown function DUF86
KMCOHGGH_03000 1.7e-47 yutD S protein conserved in bacteria
KMCOHGGH_03001 2.3e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KMCOHGGH_03002 1.2e-193 lytH M Peptidase, M23
KMCOHGGH_03003 5.1e-131 yunB S Sporulation protein YunB (Spo_YunB)
KMCOHGGH_03004 2.4e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KMCOHGGH_03005 3.9e-145 yunE S membrane transporter protein
KMCOHGGH_03006 5.3e-169 yunF S Protein of unknown function DUF72
KMCOHGGH_03007 1.5e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
KMCOHGGH_03008 4.1e-264 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KMCOHGGH_03009 4.7e-304 pucR QT COG2508 Regulator of polyketide synthase expression
KMCOHGGH_03012 1e-88 S Aspartate phosphatase response regulator
KMCOHGGH_03013 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_03014 2.2e-54 L COG2963 Transposase and inactivated derivatives
KMCOHGGH_03015 3.8e-66
KMCOHGGH_03016 1.9e-212 blt EGP Major facilitator Superfamily
KMCOHGGH_03017 3e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KMCOHGGH_03018 2.3e-234 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KMCOHGGH_03019 4.1e-169 bsn L Ribonuclease
KMCOHGGH_03020 4.1e-206 msmX P Belongs to the ABC transporter superfamily
KMCOHGGH_03021 1e-133 yurK K UTRA
KMCOHGGH_03022 1e-159 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KMCOHGGH_03023 2.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
KMCOHGGH_03024 4.4e-158 yurN G Binding-protein-dependent transport system inner membrane component
KMCOHGGH_03025 1.1e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KMCOHGGH_03026 7.9e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KMCOHGGH_03027 5.9e-166 K helix_turn_helix, mercury resistance
KMCOHGGH_03028 3e-14
KMCOHGGH_03029 2.6e-76
KMCOHGGH_03030 7.9e-22 S Sporulation delaying protein SdpA
KMCOHGGH_03032 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KMCOHGGH_03033 1.9e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KMCOHGGH_03034 3.6e-123 Q ubiE/COQ5 methyltransferase family
KMCOHGGH_03035 1.9e-80 yncE S Protein of unknown function (DUF2691)
KMCOHGGH_03036 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KMCOHGGH_03037 3e-270 sufB O FeS cluster assembly
KMCOHGGH_03038 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KMCOHGGH_03039 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KMCOHGGH_03040 2.6e-244 sufD O assembly protein SufD
KMCOHGGH_03041 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KMCOHGGH_03042 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KMCOHGGH_03043 5.1e-145 metQ P Belongs to the NlpA lipoprotein family
KMCOHGGH_03044 4.4e-94 metI P COG2011 ABC-type metal ion transport system, permease component
KMCOHGGH_03045 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KMCOHGGH_03046 5e-57 yusD S SCP-2 sterol transfer family
KMCOHGGH_03047 1.1e-53 yusE CO Thioredoxin
KMCOHGGH_03048 2.2e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KMCOHGGH_03049 3.7e-40 yusG S Protein of unknown function (DUF2553)
KMCOHGGH_03050 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KMCOHGGH_03051 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KMCOHGGH_03052 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KMCOHGGH_03053 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
KMCOHGGH_03054 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KMCOHGGH_03055 2.9e-165 fadM E Proline dehydrogenase
KMCOHGGH_03056 6.7e-43
KMCOHGGH_03057 1.1e-53 yusN M Coat F domain
KMCOHGGH_03058 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
KMCOHGGH_03059 8.1e-288 yusP P Major facilitator superfamily
KMCOHGGH_03060 4.4e-158 ywbI2 K Transcriptional regulator
KMCOHGGH_03061 2.6e-140 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
KMCOHGGH_03062 2.5e-189 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMCOHGGH_03063 3.3e-39 yusU S Protein of unknown function (DUF2573)
KMCOHGGH_03064 3.1e-150 yusV 3.6.3.34 HP ABC transporter
KMCOHGGH_03065 1.4e-45 S YusW-like protein
KMCOHGGH_03066 0.0 pepF2 E COG1164 Oligoendopeptidase F
KMCOHGGH_03067 4e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMCOHGGH_03068 1.6e-79 dps P Belongs to the Dps family
KMCOHGGH_03069 8.3e-241 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMCOHGGH_03070 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_03071 2.3e-251 cssS 2.7.13.3 T PhoQ Sensor
KMCOHGGH_03072 1.3e-23
KMCOHGGH_03073 2.7e-158 yuxN K Transcriptional regulator
KMCOHGGH_03074 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KMCOHGGH_03075 6.6e-24 S Protein of unknown function (DUF3970)
KMCOHGGH_03076 3.2e-259 gerAA EG Spore germination protein
KMCOHGGH_03077 2e-184 gerAB E Spore germination protein
KMCOHGGH_03078 9.6e-203 gerAC S Spore germination B3/ GerAC like, C-terminal
KMCOHGGH_03079 3.3e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMCOHGGH_03080 1.1e-192 vraS 2.7.13.3 T Histidine kinase
KMCOHGGH_03081 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KMCOHGGH_03082 2.3e-127 liaG S Putative adhesin
KMCOHGGH_03083 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KMCOHGGH_03084 3.3e-46 liaI S membrane
KMCOHGGH_03085 7.5e-228 yvqJ EGP Major facilitator Superfamily
KMCOHGGH_03086 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
KMCOHGGH_03087 4.7e-227 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KMCOHGGH_03088 4.3e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMCOHGGH_03089 9.3e-167 yvrC P ABC transporter substrate-binding protein
KMCOHGGH_03090 1.2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMCOHGGH_03091 1.3e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
KMCOHGGH_03092 0.0 T PhoQ Sensor
KMCOHGGH_03093 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_03094 1.1e-36
KMCOHGGH_03095 9.9e-103 yvrI K RNA polymerase
KMCOHGGH_03096 2.7e-15 S YvrJ protein family
KMCOHGGH_03097 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
KMCOHGGH_03098 5.4e-66 yvrL S Regulatory protein YrvL
KMCOHGGH_03099 8.3e-148 fhuC 3.6.3.34 HP ABC transporter
KMCOHGGH_03100 1.2e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMCOHGGH_03101 5.6e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMCOHGGH_03102 1.5e-177 fhuD P ABC transporter
KMCOHGGH_03103 5e-125 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KMCOHGGH_03104 2.9e-236 yvsH E Arginine ornithine antiporter
KMCOHGGH_03105 3.6e-14 S Small spore protein J (Spore_SspJ)
KMCOHGGH_03106 1.1e-83 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KMCOHGGH_03107 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KMCOHGGH_03108 2.7e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KMCOHGGH_03109 4.5e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KMCOHGGH_03110 1.8e-98 modB P COG4149 ABC-type molybdate transport system, permease component
KMCOHGGH_03111 2.4e-113 yfiK K Regulator
KMCOHGGH_03112 2.3e-180 T Histidine kinase
KMCOHGGH_03113 7.3e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
KMCOHGGH_03114 2.6e-192 yfiM V ABC-2 type transporter
KMCOHGGH_03115 6.6e-199 yfiN V COG0842 ABC-type multidrug transport system, permease component
KMCOHGGH_03116 5e-156 yvgN S reductase
KMCOHGGH_03117 1.6e-85 yvgO
KMCOHGGH_03118 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KMCOHGGH_03119 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KMCOHGGH_03120 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KMCOHGGH_03121 0.0 helD 3.6.4.12 L DNA helicase
KMCOHGGH_03122 3.1e-99 yvgT S membrane
KMCOHGGH_03123 5.2e-142 S Metallo-peptidase family M12
KMCOHGGH_03124 6e-73 bdbC O Required for disulfide bond formation in some proteins
KMCOHGGH_03125 2.7e-99 bdbD O Thioredoxin
KMCOHGGH_03126 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KMCOHGGH_03127 0.0 copA 3.6.3.54 P P-type ATPase
KMCOHGGH_03128 2.6e-29 copZ P Heavy-metal-associated domain
KMCOHGGH_03129 3.7e-48 csoR S transcriptional
KMCOHGGH_03130 5.8e-194 yvaA 1.1.1.371 S Oxidoreductase
KMCOHGGH_03131 5.6e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KMCOHGGH_03132 1.9e-163 K Helix-turn-helix XRE-family like proteins
KMCOHGGH_03133 4.7e-219 ynfM EGP Major Facilitator Superfamily
KMCOHGGH_03134 2.7e-70 4.1.1.44 S Carboxymuconolactone decarboxylase family
KMCOHGGH_03135 1.4e-147 S Amidohydrolase
KMCOHGGH_03137 1.4e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMCOHGGH_03138 1.2e-45 ytnI O COG0695 Glutaredoxin and related proteins
KMCOHGGH_03139 1.6e-180 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMCOHGGH_03140 5.6e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KMCOHGGH_03141 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
KMCOHGGH_03142 2.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
KMCOHGGH_03143 3e-145 tcyK M Bacterial periplasmic substrate-binding proteins
KMCOHGGH_03144 4.2e-131 ytmJ ET Bacterial periplasmic substrate-binding proteins
KMCOHGGH_03145 3e-101 ytmI K Acetyltransferase (GNAT) domain
KMCOHGGH_03146 6.1e-160 ytlI K LysR substrate binding domain
KMCOHGGH_03147 3.8e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMCOHGGH_03148 4.2e-44 yrdF K ribonuclease inhibitor
KMCOHGGH_03149 7.9e-56
KMCOHGGH_03152 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KMCOHGGH_03153 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KMCOHGGH_03154 7.4e-143 est 3.1.1.1 S Carboxylesterase
KMCOHGGH_03155 4.8e-24 secG U Preprotein translocase subunit SecG
KMCOHGGH_03156 6e-35 yvzC K Transcriptional
KMCOHGGH_03157 3e-69 K transcriptional
KMCOHGGH_03158 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
KMCOHGGH_03159 8.8e-53 yodB K transcriptional
KMCOHGGH_03160 2.6e-258 T His Kinase A (phosphoacceptor) domain
KMCOHGGH_03161 2.6e-123 K Transcriptional regulatory protein, C terminal
KMCOHGGH_03162 9.7e-138 mutG S ABC-2 family transporter protein
KMCOHGGH_03163 1.7e-123 spaE S ABC-2 family transporter protein
KMCOHGGH_03164 4.2e-127 mutF V ABC transporter, ATP-binding protein
KMCOHGGH_03165 1.1e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMCOHGGH_03166 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KMCOHGGH_03167 5.4e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMCOHGGH_03168 3.1e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KMCOHGGH_03169 4.3e-76 yvbF K Belongs to the GbsR family
KMCOHGGH_03170 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMCOHGGH_03171 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KMCOHGGH_03172 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMCOHGGH_03173 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KMCOHGGH_03174 2.1e-85 yvbF K Belongs to the GbsR family
KMCOHGGH_03175 1.1e-55 yvbG U UPF0056 membrane protein
KMCOHGGH_03176 2.5e-161 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KMCOHGGH_03177 5.4e-113 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMCOHGGH_03178 3.1e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KMCOHGGH_03179 4.3e-76 yvbF K Belongs to the GbsR family
KMCOHGGH_03180 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMCOHGGH_03181 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KMCOHGGH_03182 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMCOHGGH_03183 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KMCOHGGH_03184 1.9e-98 yvbF K Belongs to the GbsR family
KMCOHGGH_03185 5.2e-105 yvbG U UPF0056 membrane protein
KMCOHGGH_03186 4.5e-121 exoY M Membrane
KMCOHGGH_03187 0.0 tcaA S response to antibiotic
KMCOHGGH_03188 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
KMCOHGGH_03189 6.6e-213 EGP Major facilitator Superfamily
KMCOHGGH_03190 3.6e-179
KMCOHGGH_03191 4.4e-126 S GlcNAc-PI de-N-acetylase
KMCOHGGH_03192 2.5e-143 C WbqC-like protein family
KMCOHGGH_03193 2.6e-150 M Protein involved in cellulose biosynthesis
KMCOHGGH_03194 1.1e-236 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KMCOHGGH_03195 4.7e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
KMCOHGGH_03196 5.3e-217 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KMCOHGGH_03197 4e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMCOHGGH_03198 4.7e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
KMCOHGGH_03199 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KMCOHGGH_03200 1.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KMCOHGGH_03201 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KMCOHGGH_03202 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KMCOHGGH_03203 3.1e-184 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KMCOHGGH_03204 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KMCOHGGH_03206 7.4e-253 araE EGP Major facilitator Superfamily
KMCOHGGH_03207 1.1e-204 araR K transcriptional
KMCOHGGH_03208 1.1e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMCOHGGH_03210 1.5e-155 yvbU K Transcriptional regulator
KMCOHGGH_03211 1.5e-156 yvbV EG EamA-like transporter family
KMCOHGGH_03212 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_03213 1.1e-40 L transposase activity
KMCOHGGH_03214 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KMCOHGGH_03215 8.4e-259
KMCOHGGH_03216 1.4e-181 purR7 5.1.1.1 K Transcriptional regulator
KMCOHGGH_03217 1.5e-115 yyaS S Membrane
KMCOHGGH_03218 2.6e-166 3.1.3.104 S hydrolases of the HAD superfamily
KMCOHGGH_03219 6.5e-151 ybbH_1 K RpiR family transcriptional regulator
KMCOHGGH_03220 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
KMCOHGGH_03221 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
KMCOHGGH_03222 6.7e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KMCOHGGH_03223 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KMCOHGGH_03224 3.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KMCOHGGH_03225 1.6e-76 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMCOHGGH_03226 8.8e-136 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMCOHGGH_03227 1.3e-120 yvfI K COG2186 Transcriptional regulators
KMCOHGGH_03228 3.8e-304 yvfH C L-lactate permease
KMCOHGGH_03229 3.8e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KMCOHGGH_03230 2.7e-32 yvfG S YvfG protein
KMCOHGGH_03231 8.9e-189 yvfF GM Exopolysaccharide biosynthesis protein
KMCOHGGH_03232 5.7e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KMCOHGGH_03233 3.3e-54 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KMCOHGGH_03234 9.8e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KMCOHGGH_03235 1.4e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMCOHGGH_03236 3.1e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KMCOHGGH_03237 5.4e-203 epsI GM pyruvyl transferase
KMCOHGGH_03238 3.1e-195 epsH GT2 S Glycosyltransferase like family 2
KMCOHGGH_03239 2.2e-204 epsG S EpsG family
KMCOHGGH_03240 1.9e-214 epsF GT4 M Glycosyl transferases group 1
KMCOHGGH_03241 3.1e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KMCOHGGH_03242 1.3e-218 epsD GT4 M Glycosyl transferase 4-like
KMCOHGGH_03243 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KMCOHGGH_03244 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KMCOHGGH_03245 1.9e-119 ywqC M biosynthesis protein
KMCOHGGH_03246 5.1e-78 slr K transcriptional
KMCOHGGH_03247 1.3e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KMCOHGGH_03248 7.5e-97 ywjB H RibD C-terminal domain
KMCOHGGH_03249 2.8e-111 yyaS S Membrane
KMCOHGGH_03250 6.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMCOHGGH_03251 5.5e-94 padC Q Phenolic acid decarboxylase
KMCOHGGH_03252 5.2e-13 S Protein of unknown function (DUF1433)
KMCOHGGH_03253 3.5e-24 S Protein of unknown function (DUF1433)
KMCOHGGH_03254 4.8e-13 S Protein of unknown function (DUF1433)
KMCOHGGH_03255 9.8e-20 S Protein of unknown function (DUF1433)
KMCOHGGH_03256 3.3e-214 I Pfam Lipase (class 3)
KMCOHGGH_03257 3.1e-34
KMCOHGGH_03259 2e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
KMCOHGGH_03260 2.8e-219 rafB P LacY proton/sugar symporter
KMCOHGGH_03261 3.3e-183 scrR K transcriptional
KMCOHGGH_03262 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KMCOHGGH_03263 3.3e-163 yraN K Transcriptional regulator
KMCOHGGH_03264 1.3e-215 yraM S PrpF protein
KMCOHGGH_03265 9.8e-250 EGP Sugar (and other) transporter
KMCOHGGH_03266 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KMCOHGGH_03267 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
KMCOHGGH_03268 7.3e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KMCOHGGH_03269 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KMCOHGGH_03270 8.6e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMCOHGGH_03271 1.6e-79 M Ribonuclease
KMCOHGGH_03272 2.6e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KMCOHGGH_03273 4.7e-36 crh G Phosphocarrier protein Chr
KMCOHGGH_03274 3.1e-170 whiA K May be required for sporulation
KMCOHGGH_03275 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KMCOHGGH_03276 1.1e-166 rapZ S Displays ATPase and GTPase activities
KMCOHGGH_03277 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KMCOHGGH_03278 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KMCOHGGH_03279 5e-124 usp CBM50 M protein conserved in bacteria
KMCOHGGH_03280 5e-276 S COG0457 FOG TPR repeat
KMCOHGGH_03281 1.6e-191 sasA T Histidine kinase
KMCOHGGH_03282 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_03283 0.0 msbA2 3.6.3.44 V ABC transporter
KMCOHGGH_03284 5.6e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KMCOHGGH_03285 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KMCOHGGH_03286 7.6e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KMCOHGGH_03287 1.5e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KMCOHGGH_03288 1.1e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KMCOHGGH_03289 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KMCOHGGH_03290 1.3e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KMCOHGGH_03291 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KMCOHGGH_03292 2e-137 yvpB NU protein conserved in bacteria
KMCOHGGH_03293 1.9e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KMCOHGGH_03294 2.4e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KMCOHGGH_03295 2.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KMCOHGGH_03296 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KMCOHGGH_03297 8.6e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KMCOHGGH_03298 8e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KMCOHGGH_03299 4e-133 yvoA K transcriptional
KMCOHGGH_03300 1.8e-104 yxaF K Transcriptional regulator
KMCOHGGH_03301 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KMCOHGGH_03302 3.9e-41 yvlD S Membrane
KMCOHGGH_03303 9.6e-26 pspB KT PspC domain
KMCOHGGH_03304 9.2e-166 yvlB S Putative adhesin
KMCOHGGH_03305 4e-48 yvlA
KMCOHGGH_03306 6.6e-38 yvkN
KMCOHGGH_03307 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KMCOHGGH_03308 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KMCOHGGH_03309 7.6e-33 csbA S protein conserved in bacteria
KMCOHGGH_03310 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KMCOHGGH_03311 2.4e-110 yvkB K Transcriptional regulator
KMCOHGGH_03312 3e-227 yvkA EGP Major facilitator Superfamily
KMCOHGGH_03313 5.8e-25 bacT Q Thioesterase domain
KMCOHGGH_03315 1.1e-176 S Psort location CytoplasmicMembrane, score
KMCOHGGH_03316 2.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMCOHGGH_03317 1.5e-55 swrA S Swarming motility protein
KMCOHGGH_03318 2.7e-255 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KMCOHGGH_03319 4.1e-227 ywoF P Right handed beta helix region
KMCOHGGH_03320 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KMCOHGGH_03321 1e-122 ftsE D cell division ATP-binding protein FtsE
KMCOHGGH_03322 4e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
KMCOHGGH_03323 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KMCOHGGH_03324 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KMCOHGGH_03325 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KMCOHGGH_03326 4.8e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KMCOHGGH_03327 6.8e-68
KMCOHGGH_03328 2.6e-10 fliT S bacterial-type flagellum organization
KMCOHGGH_03329 3e-66 fliS N flagellar protein FliS
KMCOHGGH_03330 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KMCOHGGH_03331 2e-103 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KMCOHGGH_03332 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KMCOHGGH_03333 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KMCOHGGH_03334 1.4e-80 yviE
KMCOHGGH_03335 6.1e-163 flgL N Belongs to the bacterial flagellin family
KMCOHGGH_03336 3.7e-274 flgK N flagellar hook-associated protein
KMCOHGGH_03337 8.9e-81 flgN NOU FlgN protein
KMCOHGGH_03338 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
KMCOHGGH_03339 9.2e-74 yvyF S flagellar protein
KMCOHGGH_03340 1.3e-67 comFC S Phosphoribosyl transferase domain
KMCOHGGH_03341 1.5e-43 comFB S Late competence development protein ComFB
KMCOHGGH_03342 8.6e-262 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KMCOHGGH_03343 1.6e-157 degV S protein conserved in bacteria
KMCOHGGH_03344 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMCOHGGH_03345 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KMCOHGGH_03346 2.2e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KMCOHGGH_03347 3e-173 yvhJ K Transcriptional regulator
KMCOHGGH_03348 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KMCOHGGH_03349 2.3e-239 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KMCOHGGH_03350 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
KMCOHGGH_03351 1.6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
KMCOHGGH_03352 2.5e-256 tuaE M Teichuronic acid biosynthesis protein
KMCOHGGH_03353 6.6e-251 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMCOHGGH_03354 3.6e-224 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KMCOHGGH_03355 1.3e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMCOHGGH_03356 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KMCOHGGH_03357 9.3e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KMCOHGGH_03358 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KMCOHGGH_03359 5.9e-49
KMCOHGGH_03360 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KMCOHGGH_03361 4.4e-211 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KMCOHGGH_03362 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KMCOHGGH_03363 8.9e-284 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KMCOHGGH_03364 1.7e-151 tagG GM Transport permease protein
KMCOHGGH_03365 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KMCOHGGH_03366 3.3e-294 M Glycosyltransferase like family 2
KMCOHGGH_03367 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KMCOHGGH_03368 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KMCOHGGH_03369 4e-220 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KMCOHGGH_03370 2.7e-235 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KMCOHGGH_03371 1.3e-187 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KMCOHGGH_03372 1.3e-265 gerBA EG Spore germination protein
KMCOHGGH_03373 4.9e-199 gerBB E Spore germination protein
KMCOHGGH_03374 4.2e-214 gerAC S Spore germination protein
KMCOHGGH_03375 4e-267 GT2,GT4 J Glycosyl transferase family 2
KMCOHGGH_03376 3.7e-249 ywtG EGP Major facilitator Superfamily
KMCOHGGH_03377 1.9e-178 ywtF K Transcriptional regulator
KMCOHGGH_03378 4.5e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KMCOHGGH_03379 2e-36 yttA 2.7.13.3 S Pfam Transposase IS66
KMCOHGGH_03380 9.8e-241 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KMCOHGGH_03381 1.3e-20 ywtC
KMCOHGGH_03382 1.7e-133 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KMCOHGGH_03383 1.6e-58 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KMCOHGGH_03384 2.3e-70 pgsC S biosynthesis protein
KMCOHGGH_03385 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KMCOHGGH_03386 7.7e-184 gerKA EG Spore germination protein
KMCOHGGH_03387 2.8e-191 gerKB E Spore germination protein
KMCOHGGH_03388 6.7e-204 gerKC S Spore germination B3/ GerAC like, C-terminal
KMCOHGGH_03389 7.2e-178 rbsR K transcriptional
KMCOHGGH_03390 3e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMCOHGGH_03391 9.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KMCOHGGH_03392 4.9e-279 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KMCOHGGH_03393 3.2e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
KMCOHGGH_03394 2e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KMCOHGGH_03395 5.2e-90 batE T Sh3 type 3 domain protein
KMCOHGGH_03396 1.1e-95 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
KMCOHGGH_03397 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KMCOHGGH_03398 1.2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KMCOHGGH_03399 9e-167 alsR K LysR substrate binding domain
KMCOHGGH_03400 3.6e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KMCOHGGH_03401 4.4e-126 ywrJ
KMCOHGGH_03402 1.6e-128 cotB
KMCOHGGH_03403 3.8e-212 cotH M Spore Coat
KMCOHGGH_03404 2e-09
KMCOHGGH_03405 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KMCOHGGH_03406 6.1e-07 S Domain of unknown function (DUF4181)
KMCOHGGH_03407 3.3e-302 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KMCOHGGH_03408 1.1e-83 ywrC K Transcriptional regulator
KMCOHGGH_03409 4.6e-103 ywrB P Chromate transporter
KMCOHGGH_03410 8.4e-88 ywrA P COG2059 Chromate transport protein ChrA
KMCOHGGH_03411 1.5e-97 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KMCOHGGH_03412 1.1e-24
KMCOHGGH_03413 1.7e-257 ywqJ S Pre-toxin TG
KMCOHGGH_03414 9.5e-37 ywqI S Family of unknown function (DUF5344)
KMCOHGGH_03415 8.5e-22 S Domain of unknown function (DUF5082)
KMCOHGGH_03417 3e-150 ywqG S Domain of unknown function (DUF1963)
KMCOHGGH_03418 1.5e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMCOHGGH_03419 3.2e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KMCOHGGH_03420 1.5e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KMCOHGGH_03421 5.2e-112 ywqC M biosynthesis protein
KMCOHGGH_03422 1.3e-14
KMCOHGGH_03423 3.2e-308 ywqB S SWIM zinc finger
KMCOHGGH_03424 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KMCOHGGH_03425 1.1e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KMCOHGGH_03426 5.4e-136 glcR K DeoR C terminal sensor domain
KMCOHGGH_03427 1.7e-57 ssbB L Single-stranded DNA-binding protein
KMCOHGGH_03428 4e-62 ywpG
KMCOHGGH_03429 1.1e-68 ywpF S YwpF-like protein
KMCOHGGH_03430 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KMCOHGGH_03431 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KMCOHGGH_03432 2.9e-201 S aspartate phosphatase
KMCOHGGH_03433 2.6e-144 flhP N flagellar basal body
KMCOHGGH_03434 4.7e-127 flhO N flagellar basal body
KMCOHGGH_03435 2.7e-180 mbl D Rod shape-determining protein
KMCOHGGH_03436 1.8e-44 spoIIID K Stage III sporulation protein D
KMCOHGGH_03437 8.5e-72 ywoH K transcriptional
KMCOHGGH_03438 2.4e-212 ywoG EGP Major facilitator Superfamily
KMCOHGGH_03439 1.6e-274 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KMCOHGGH_03440 1.5e-242 ywoD EGP Major facilitator superfamily
KMCOHGGH_03441 1.4e-101 phzA Q Isochorismatase family
KMCOHGGH_03442 3.5e-227 amt P Ammonium transporter
KMCOHGGH_03443 2e-58 nrgB K Belongs to the P(II) protein family
KMCOHGGH_03444 2.4e-209 ftsW D Belongs to the SEDS family
KMCOHGGH_03445 4.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KMCOHGGH_03446 5.1e-72 ywnJ S VanZ like family
KMCOHGGH_03447 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KMCOHGGH_03448 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KMCOHGGH_03449 1.2e-10 ywnC S Family of unknown function (DUF5362)
KMCOHGGH_03450 1.6e-68 ywnF S Family of unknown function (DUF5392)
KMCOHGGH_03451 8.4e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMCOHGGH_03452 1.7e-53 ywnC S Family of unknown function (DUF5362)
KMCOHGGH_03453 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
KMCOHGGH_03454 6.1e-67 ywnA K Transcriptional regulator
KMCOHGGH_03455 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KMCOHGGH_03456 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KMCOHGGH_03457 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KMCOHGGH_03458 6.5e-11 csbD K CsbD-like
KMCOHGGH_03459 2.1e-82 ywmF S Peptidase M50
KMCOHGGH_03460 2.8e-93 S response regulator aspartate phosphatase
KMCOHGGH_03461 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KMCOHGGH_03462 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KMCOHGGH_03464 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KMCOHGGH_03465 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KMCOHGGH_03466 3.6e-188 spoIID D Stage II sporulation protein D
KMCOHGGH_03467 1.4e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMCOHGGH_03468 4.8e-134 ywmB S TATA-box binding
KMCOHGGH_03469 4.8e-32 ywzB S membrane
KMCOHGGH_03470 1.2e-90 ywmA
KMCOHGGH_03471 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KMCOHGGH_03472 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KMCOHGGH_03473 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KMCOHGGH_03474 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KMCOHGGH_03475 2.2e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMCOHGGH_03476 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KMCOHGGH_03477 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMCOHGGH_03478 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
KMCOHGGH_03479 2.1e-61 atpI S ATP synthase
KMCOHGGH_03480 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KMCOHGGH_03481 2.8e-235 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KMCOHGGH_03482 5.9e-97 ywlG S Belongs to the UPF0340 family
KMCOHGGH_03483 1.9e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KMCOHGGH_03484 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMCOHGGH_03485 9e-85 mntP P Probably functions as a manganese efflux pump
KMCOHGGH_03486 1e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KMCOHGGH_03487 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KMCOHGGH_03488 8.9e-119 spoIIR S stage II sporulation protein R
KMCOHGGH_03489 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
KMCOHGGH_03491 3.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KMCOHGGH_03492 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KMCOHGGH_03493 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMCOHGGH_03494 1.1e-93 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KMCOHGGH_03495 3.6e-158 ywkB S Membrane transport protein
KMCOHGGH_03496 0.0 sfcA 1.1.1.38 C malic enzyme
KMCOHGGH_03497 1.4e-104 tdk 2.7.1.21 F thymidine kinase
KMCOHGGH_03498 1.1e-32 rpmE J Binds the 23S rRNA
KMCOHGGH_03499 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KMCOHGGH_03500 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KMCOHGGH_03501 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMCOHGGH_03502 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KMCOHGGH_03503 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KMCOHGGH_03504 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
KMCOHGGH_03505 1.7e-93 ywjG S Domain of unknown function (DUF2529)
KMCOHGGH_03506 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KMCOHGGH_03507 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KMCOHGGH_03508 0.0 fadF C COG0247 Fe-S oxidoreductase
KMCOHGGH_03509 9.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KMCOHGGH_03510 1.2e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KMCOHGGH_03511 4.2e-43 ywjC
KMCOHGGH_03512 0.0 ywjA V ABC transporter
KMCOHGGH_03513 9e-289 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMCOHGGH_03514 1.4e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMCOHGGH_03515 4.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
KMCOHGGH_03516 1.9e-95 narJ 1.7.5.1 C nitrate reductase
KMCOHGGH_03517 6.9e-294 narH 1.7.5.1 C Nitrate reductase, beta
KMCOHGGH_03518 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMCOHGGH_03519 2e-85 arfM T cyclic nucleotide binding
KMCOHGGH_03520 3.1e-138 ywiC S YwiC-like protein
KMCOHGGH_03521 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
KMCOHGGH_03522 5.8e-214 narK P COG2223 Nitrate nitrite transporter
KMCOHGGH_03523 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KMCOHGGH_03524 1.2e-73 ywiB S protein conserved in bacteria
KMCOHGGH_03525 1.3e-230 ywhL CO amine dehydrogenase activity
KMCOHGGH_03526 1.1e-221 ywhK CO amine dehydrogenase activity
KMCOHGGH_03527 1.4e-76 S aspartate phosphatase
KMCOHGGH_03529 2.6e-29 ydcG K sequence-specific DNA binding
KMCOHGGH_03530 5e-33
KMCOHGGH_03531 2e-28 S Domain of unknown function (DUF4177)
KMCOHGGH_03533 1.8e-76 CP Membrane
KMCOHGGH_03536 2.7e-168 speB 3.5.3.11 E Belongs to the arginase family
KMCOHGGH_03537 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KMCOHGGH_03538 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KMCOHGGH_03539 8.5e-83
KMCOHGGH_03540 1.4e-95 ywhD S YwhD family
KMCOHGGH_03541 1.2e-117 ywhC S Peptidase family M50
KMCOHGGH_03542 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KMCOHGGH_03543 8e-70 ywhA K Transcriptional regulator
KMCOHGGH_03544 1.3e-246 yhdG_1 E C-terminus of AA_permease
KMCOHGGH_03545 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
KMCOHGGH_03546 7.9e-257 ywfO S COG1078 HD superfamily phosphohydrolases
KMCOHGGH_03547 6.9e-36 ywzC S Belongs to the UPF0741 family
KMCOHGGH_03548 6.6e-110 rsfA_1
KMCOHGGH_03549 8.2e-51 padR K PadR family transcriptional regulator
KMCOHGGH_03550 5.2e-93 S membrane
KMCOHGGH_03551 9.1e-167 V ABC transporter, ATP-binding protein
KMCOHGGH_03552 4.5e-169 yhcI S ABC transporter (permease)
KMCOHGGH_03555 1.4e-186
KMCOHGGH_03557 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KMCOHGGH_03558 3e-162 cysL K Transcriptional regulator
KMCOHGGH_03559 1.8e-157 MA20_14895 S Conserved hypothetical protein 698
KMCOHGGH_03560 1.1e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KMCOHGGH_03561 1.1e-146 ywfI C May function as heme-dependent peroxidase
KMCOHGGH_03562 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
KMCOHGGH_03563 1.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
KMCOHGGH_03564 4.7e-208 bacE EGP Major facilitator Superfamily
KMCOHGGH_03565 4.4e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KMCOHGGH_03566 4.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMCOHGGH_03567 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KMCOHGGH_03568 3.3e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KMCOHGGH_03569 3.2e-223 ywfA EGP Major facilitator Superfamily
KMCOHGGH_03570 9e-207 tcaB EGP Major facilitator Superfamily
KMCOHGGH_03571 1.4e-259 lysP E amino acid
KMCOHGGH_03572 0.0 rocB E arginine degradation protein
KMCOHGGH_03573 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KMCOHGGH_03574 2.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KMCOHGGH_03575 8.4e-60
KMCOHGGH_03576 7.9e-87 spsL 5.1.3.13 M Spore Coat
KMCOHGGH_03577 8.1e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KMCOHGGH_03578 9.3e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KMCOHGGH_03579 6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KMCOHGGH_03580 3.6e-185 spsG M Spore Coat
KMCOHGGH_03581 6.3e-134 spsF M Spore Coat
KMCOHGGH_03582 8.4e-215 spsE 2.5.1.56 M acid synthase
KMCOHGGH_03583 1e-159 spsD 2.3.1.210 K Spore Coat
KMCOHGGH_03584 3.3e-222 spsC E Belongs to the DegT DnrJ EryC1 family
KMCOHGGH_03585 1.7e-276 spsB M Capsule polysaccharide biosynthesis protein
KMCOHGGH_03586 2.6e-143 spsA M Spore Coat
KMCOHGGH_03587 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KMCOHGGH_03588 1.6e-45 ywdK S small membrane protein
KMCOHGGH_03589 7.5e-231 ywdJ F Xanthine uracil
KMCOHGGH_03590 4.7e-41 ywdI S Family of unknown function (DUF5327)
KMCOHGGH_03591 2.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KMCOHGGH_03592 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
KMCOHGGH_03594 7.6e-88 ywdD
KMCOHGGH_03595 6.3e-57 pex K Transcriptional regulator PadR-like family
KMCOHGGH_03596 1e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KMCOHGGH_03597 9.7e-20 ywdA
KMCOHGGH_03598 8.6e-289 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
KMCOHGGH_03599 1.8e-251 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMCOHGGH_03600 2e-07 sacT K transcriptional antiterminator
KMCOHGGH_03601 8.3e-151 sacT K transcriptional antiterminator
KMCOHGGH_03603 0.0 vpr O Belongs to the peptidase S8 family
KMCOHGGH_03604 4.4e-183 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMCOHGGH_03605 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KMCOHGGH_03606 2.8e-208 rodA D Belongs to the SEDS family
KMCOHGGH_03607 3.7e-80 ysnE K acetyltransferase
KMCOHGGH_03608 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
KMCOHGGH_03609 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KMCOHGGH_03610 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KMCOHGGH_03611 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KMCOHGGH_03612 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KMCOHGGH_03613 8.4e-27 ywzA S membrane
KMCOHGGH_03614 3.5e-296 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KMCOHGGH_03615 5.7e-230 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KMCOHGGH_03616 2.7e-62 gtcA S GtrA-like protein
KMCOHGGH_03617 1.6e-111 ywcC K Bacterial regulatory proteins, tetR family
KMCOHGGH_03619 1.9e-129 H Methionine biosynthesis protein MetW
KMCOHGGH_03620 3.7e-133 S Streptomycin biosynthesis protein StrF
KMCOHGGH_03621 1.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KMCOHGGH_03622 3.7e-243 ywbN P Dyp-type peroxidase family protein
KMCOHGGH_03623 1.9e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KMCOHGGH_03624 4.3e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KMCOHGGH_03625 8.2e-152 ywbI K Transcriptional regulator
KMCOHGGH_03626 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KMCOHGGH_03627 3.4e-110 ywbG M effector of murein hydrolase
KMCOHGGH_03628 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
KMCOHGGH_03629 5.5e-225 ywbD 2.1.1.191 J Methyltransferase
KMCOHGGH_03630 7.6e-67 ywbC 4.4.1.5 E glyoxalase
KMCOHGGH_03631 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMCOHGGH_03632 9.5e-266 epr 3.4.21.62 O Belongs to the peptidase S8 family
KMCOHGGH_03633 1.1e-163 gspA M General stress
KMCOHGGH_03634 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
KMCOHGGH_03635 1.7e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KMCOHGGH_03636 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
KMCOHGGH_03637 3.5e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_03638 3.1e-228 dltB M membrane protein involved in D-alanine export
KMCOHGGH_03639 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMCOHGGH_03640 1.8e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KMCOHGGH_03641 1.1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KMCOHGGH_03642 9.2e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KMCOHGGH_03643 7.8e-52 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KMCOHGGH_03644 2.8e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMCOHGGH_03645 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KMCOHGGH_03646 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KMCOHGGH_03647 2.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KMCOHGGH_03648 1.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMCOHGGH_03649 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMCOHGGH_03650 4e-167 cbrA3 P Periplasmic binding protein
KMCOHGGH_03651 2.2e-57 arsR K transcriptional
KMCOHGGH_03652 2.2e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KMCOHGGH_03653 6.2e-35 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KMCOHGGH_03654 9.1e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KMCOHGGH_03655 1.4e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMCOHGGH_03656 1.5e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KMCOHGGH_03657 2.3e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KMCOHGGH_03658 9e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
KMCOHGGH_03659 4.2e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KMCOHGGH_03660 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KMCOHGGH_03661 7.2e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KMCOHGGH_03662 3.6e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KMCOHGGH_03663 5.9e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KMCOHGGH_03664 1.7e-291 cydD V ATP-binding protein
KMCOHGGH_03665 4.7e-311 cydD V ATP-binding
KMCOHGGH_03666 1.5e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KMCOHGGH_03667 2.6e-266 cydA 1.10.3.14 C oxidase, subunit
KMCOHGGH_03668 4.5e-215 cimH C COG3493 Na citrate symporter
KMCOHGGH_03669 1.6e-157 yxkH G Polysaccharide deacetylase
KMCOHGGH_03670 2.6e-205 msmK P Belongs to the ABC transporter superfamily
KMCOHGGH_03671 3e-167 lrp QT PucR C-terminal helix-turn-helix domain
KMCOHGGH_03672 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMCOHGGH_03673 1.4e-86 yxkC S Domain of unknown function (DUF4352)
KMCOHGGH_03674 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KMCOHGGH_03675 4.2e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KMCOHGGH_03678 1.2e-69 yxjI S LURP-one-related
KMCOHGGH_03679 1.1e-217 yxjG 2.1.1.14 E Methionine synthase
KMCOHGGH_03680 2.2e-162 rlmA 2.1.1.187 Q Methyltransferase domain
KMCOHGGH_03681 4.6e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMCOHGGH_03682 2.7e-75 T Domain of unknown function (DUF4163)
KMCOHGGH_03683 1.4e-50 yxiS
KMCOHGGH_03684 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KMCOHGGH_03685 2.8e-222 citH C Citrate transporter
KMCOHGGH_03686 1.5e-143 exoK GH16 M licheninase activity
KMCOHGGH_03687 7.7e-149 licT K transcriptional antiterminator
KMCOHGGH_03688 2.4e-223 yxiO S COG2270 Permeases of the major facilitator superfamily
KMCOHGGH_03689 3.1e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KMCOHGGH_03692 1.8e-30 S SMI1-KNR4 cell-wall
KMCOHGGH_03693 3.9e-81 yxiI S Protein of unknown function (DUF2716)
KMCOHGGH_03695 8.1e-22
KMCOHGGH_03696 1.3e-12 S YxiJ-like protein
KMCOHGGH_03701 6.2e-36
KMCOHGGH_03702 0.0 wapA M COG3209 Rhs family protein
KMCOHGGH_03703 1.7e-201 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
KMCOHGGH_03704 3e-146 yxxF EG EamA-like transporter family
KMCOHGGH_03705 9.8e-74 yxiE T Belongs to the universal stress protein A family
KMCOHGGH_03706 1.2e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KMCOHGGH_03707 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMCOHGGH_03708 0.0 L HKD family nuclease
KMCOHGGH_03709 1.9e-65 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KMCOHGGH_03710 2.1e-171 3.6.4.12 L AAA domain
KMCOHGGH_03711 6.7e-278 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KMCOHGGH_03712 3.8e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KMCOHGGH_03713 1.5e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
KMCOHGGH_03714 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KMCOHGGH_03715 4.7e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
KMCOHGGH_03716 7.7e-177 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KMCOHGGH_03717 2e-253 lysP E amino acid
KMCOHGGH_03718 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KMCOHGGH_03719 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMCOHGGH_03720 1.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KMCOHGGH_03721 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KMCOHGGH_03722 4.4e-149 yidA S hydrolases of the HAD superfamily
KMCOHGGH_03725 6.4e-13 yxeE
KMCOHGGH_03727 8.4e-23 yxeD
KMCOHGGH_03728 6e-35
KMCOHGGH_03729 3.9e-176 fhuD P Periplasmic binding protein
KMCOHGGH_03730 1.3e-57 yxeA S Protein of unknown function (DUF1093)
KMCOHGGH_03731 0.0 yxdM V ABC transporter (permease)
KMCOHGGH_03732 6.1e-140 yxdL V ABC transporter, ATP-binding protein
KMCOHGGH_03733 4.8e-174 T PhoQ Sensor
KMCOHGGH_03734 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_03735 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KMCOHGGH_03736 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KMCOHGGH_03737 1.1e-166 iolH G Xylose isomerase-like TIM barrel
KMCOHGGH_03738 5.6e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KMCOHGGH_03739 6.7e-232 iolF EGP Major facilitator Superfamily
KMCOHGGH_03740 1.9e-177 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KMCOHGGH_03741 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KMCOHGGH_03742 4.4e-183 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KMCOHGGH_03743 1.5e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KMCOHGGH_03744 9.7e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMCOHGGH_03745 5.2e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
KMCOHGGH_03746 4.9e-176 iolS C Aldo keto reductase
KMCOHGGH_03747 6.7e-246 csbC EGP Major facilitator Superfamily
KMCOHGGH_03748 0.0 htpG O Molecular chaperone. Has ATPase activity
KMCOHGGH_03750 2.1e-151 IQ Enoyl-(Acyl carrier protein) reductase
KMCOHGGH_03751 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMCOHGGH_03752 5.9e-200 desK 2.7.13.3 T Histidine kinase
KMCOHGGH_03753 2.6e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KMCOHGGH_03754 1.6e-216 yxbF K Bacterial regulatory proteins, tetR family
KMCOHGGH_03755 2.5e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KMCOHGGH_03756 6.8e-141 S PQQ-like domain
KMCOHGGH_03757 7.6e-60 S Family of unknown function (DUF5391)
KMCOHGGH_03758 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
KMCOHGGH_03759 5e-202 EGP Major facilitator Superfamily
KMCOHGGH_03760 2.2e-73 yxaI S membrane protein domain
KMCOHGGH_03761 2.1e-128 E Ring-cleavage extradiol dioxygenase
KMCOHGGH_03762 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KMCOHGGH_03763 2.9e-287 ahpF O Alkyl hydroperoxide reductase
KMCOHGGH_03764 1e-229 XK27_00240 S Fic/DOC family
KMCOHGGH_03765 1.4e-245 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
KMCOHGGH_03766 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KMCOHGGH_03767 7.4e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KMCOHGGH_03768 1.6e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KMCOHGGH_03769 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KMCOHGGH_03770 7.9e-90 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KMCOHGGH_03771 9.7e-186 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KMCOHGGH_03772 2.3e-177 S Fusaric acid resistance protein-like
KMCOHGGH_03773 3.8e-11 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KMCOHGGH_03774 8.1e-63 K ParB-like nuclease domain
KMCOHGGH_03775 6e-21 S Restriction endonuclease
KMCOHGGH_03776 3.7e-96 cca 2.7.7.19, 2.7.7.72 J COG0617 tRNA nucleotidyltransferase poly(A) polymerase
KMCOHGGH_03777 3e-238 dgt 3.1.5.1 F dGTP triphosphohydrolase
KMCOHGGH_03778 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KMCOHGGH_03779 7.9e-08 S YyzF-like protein
KMCOHGGH_03781 1.4e-217 yycP
KMCOHGGH_03782 8.3e-134 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KMCOHGGH_03783 3.5e-185 C oxidoreductases (related to aryl-alcohol dehydrogenases)
KMCOHGGH_03784 3.7e-87 yycN 2.3.1.128 K Acetyltransferase
KMCOHGGH_03786 2.2e-199 S Histidine kinase
KMCOHGGH_03787 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KMCOHGGH_03788 2.6e-258 rocE E amino acid
KMCOHGGH_03789 1.9e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KMCOHGGH_03790 3.4e-261 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KMCOHGGH_03791 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
KMCOHGGH_03792 5.7e-305 S ABC transporter
KMCOHGGH_03793 3.4e-198 S Major Facilitator Superfamily
KMCOHGGH_03794 1e-259
KMCOHGGH_03795 3.4e-191 2.7.7.73, 2.7.7.80 H ThiF family
KMCOHGGH_03796 2.9e-252 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
KMCOHGGH_03797 5.2e-09 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_03798 1.2e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMCOHGGH_03799 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KMCOHGGH_03800 7.5e-152 yycI S protein conserved in bacteria
KMCOHGGH_03801 1.8e-259 yycH S protein conserved in bacteria
KMCOHGGH_03802 0.0 vicK 2.7.13.3 T Histidine kinase
KMCOHGGH_03803 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMCOHGGH_03808 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KMCOHGGH_03809 9.1e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMCOHGGH_03810 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KMCOHGGH_03811 6.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KMCOHGGH_03813 3.5e-17 yycC K YycC-like protein
KMCOHGGH_03814 6e-241 M Glycosyltransferase Family 4
KMCOHGGH_03815 5.1e-206 S Ecdysteroid kinase
KMCOHGGH_03816 6.5e-234 S Carbamoyl-phosphate synthase L chain, ATP binding domain
KMCOHGGH_03817 1.9e-242 M Glycosyltransferase Family 4
KMCOHGGH_03818 1.7e-122 S GlcNAc-PI de-N-acetylase
KMCOHGGH_03819 3.8e-122 KLT COG0515 Serine threonine protein kinase
KMCOHGGH_03820 1.4e-72 rplI J binds to the 23S rRNA
KMCOHGGH_03821 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KMCOHGGH_03822 1.6e-158 yybS S membrane
KMCOHGGH_03824 6e-85 cotF M Spore coat protein
KMCOHGGH_03825 8.2e-66 ydeP3 K Transcriptional regulator
KMCOHGGH_03826 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KMCOHGGH_03827 2.2e-54 L COG2963 Transposase and inactivated derivatives
KMCOHGGH_03828 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
KMCOHGGH_03829 4.4e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KMCOHGGH_03830 2.2e-273 sacB 2.4.1.10 GH68 M levansucrase activity
KMCOHGGH_03831 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
KMCOHGGH_03832 1.8e-116 K FCD domain
KMCOHGGH_03833 2.4e-76 dinB S PFAM DinB family protein
KMCOHGGH_03834 8.9e-162 G Major Facilitator Superfamily
KMCOHGGH_03835 1.9e-14 comA K response regulator
KMCOHGGH_03836 2e-244 trpE 2.6.1.85, 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KMCOHGGH_03837 9e-77 eamA1 EG spore germination
KMCOHGGH_03838 4.9e-77 H porphobilinogen synthase activity
KMCOHGGH_03839 6e-160 yfiE K LysR substrate binding domain
KMCOHGGH_03840 4.3e-100 E LysE type translocator
KMCOHGGH_03841 9.9e-56 ypaA S Protein of unknown function (DUF1304)
KMCOHGGH_03842 5.6e-115 drgA C nitroreductase
KMCOHGGH_03843 3.2e-69 ydgJ K Winged helix DNA-binding domain
KMCOHGGH_03844 9.3e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KMCOHGGH_03845 2.5e-77 yybA 2.3.1.57 K transcriptional
KMCOHGGH_03846 8.5e-75 yjcF S Acetyltransferase (GNAT) domain
KMCOHGGH_03847 9.8e-163 eaeH M Domain of Unknown Function (DUF1259)
KMCOHGGH_03848 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
KMCOHGGH_03849 4.5e-166 K Transcriptional regulator
KMCOHGGH_03850 3.1e-142 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KMCOHGGH_03851 1.8e-249 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMCOHGGH_03852 1.2e-129 ydfC EG EamA-like transporter family
KMCOHGGH_03853 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KMCOHGGH_03854 1.4e-164 yyaK S CAAX protease self-immunity
KMCOHGGH_03855 1.2e-247 ydjK G Sugar (and other) transporter
KMCOHGGH_03856 1.7e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMCOHGGH_03857 1.3e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KMCOHGGH_03858 1.6e-145 xth 3.1.11.2 L exodeoxyribonuclease III
KMCOHGGH_03859 3.1e-101 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KMCOHGGH_03860 4.3e-106 adaA 3.2.2.21 K Transcriptional regulator
KMCOHGGH_03861 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KMCOHGGH_03862 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KMCOHGGH_03863 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
KMCOHGGH_03864 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KMCOHGGH_03865 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMCOHGGH_03866 2.3e-33 yyzM S protein conserved in bacteria
KMCOHGGH_03867 2.4e-176 yyaD S Membrane
KMCOHGGH_03868 1.1e-84 4.2.1.103 K FR47-like protein
KMCOHGGH_03869 6.2e-111 yyaC S Sporulation protein YyaC
KMCOHGGH_03870 8.8e-148 spo0J K Belongs to the ParB family
KMCOHGGH_03871 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
KMCOHGGH_03872 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KMCOHGGH_03873 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KMCOHGGH_03874 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KMCOHGGH_03875 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KMCOHGGH_03876 4.2e-110 jag S single-stranded nucleic acid binding R3H
KMCOHGGH_03877 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)