ORF_ID e_value Gene_name EC_number CAZy COGs Description
NHPPAGDG_00001 1.9e-209 yfmO EGP Major facilitator Superfamily
NHPPAGDG_00002 1.4e-69 yfmP K transcriptional
NHPPAGDG_00003 5.7e-74 yfmQ S Uncharacterised protein from bacillus cereus group
NHPPAGDG_00004 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHPPAGDG_00005 4.6e-112 yfmS NT chemotaxis protein
NHPPAGDG_00006 1.8e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHPPAGDG_00007 1.4e-240 yfnA E amino acid
NHPPAGDG_00008 2.8e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NHPPAGDG_00009 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
NHPPAGDG_00010 2.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
NHPPAGDG_00011 5.1e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NHPPAGDG_00012 2.1e-179 yfnF M Nucleotide-diphospho-sugar transferase
NHPPAGDG_00013 1.9e-172 yfnG 4.2.1.45 M dehydratase
NHPPAGDG_00014 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
NHPPAGDG_00015 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NHPPAGDG_00016 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NHPPAGDG_00017 2.4e-195 yetN S Protein of unknown function (DUF3900)
NHPPAGDG_00018 7.2e-189 yfmJ S N-terminal domain of oxidoreductase
NHPPAGDG_00019 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
NHPPAGDG_00020 2.2e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NHPPAGDG_00021 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHPPAGDG_00026 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_00027 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NHPPAGDG_00028 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHPPAGDG_00029 8.3e-223 ybbR S protein conserved in bacteria
NHPPAGDG_00030 2.3e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHPPAGDG_00031 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHPPAGDG_00032 2.1e-168 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NHPPAGDG_00033 7.2e-36 adaA 3.2.2.21 K Transcriptional regulator
NHPPAGDG_00034 3e-37 adaA 3.2.2.21 K Transcriptional regulator
NHPPAGDG_00035 1.5e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHPPAGDG_00036 6.3e-274 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NHPPAGDG_00037 0.0 ybcC S Belongs to the UPF0753 family
NHPPAGDG_00038 1.5e-92 can 4.2.1.1 P carbonic anhydrase
NHPPAGDG_00040 8.7e-47
NHPPAGDG_00041 1.8e-60 ybcI S Uncharacterized conserved protein (DUF2294)
NHPPAGDG_00042 5.1e-50 ybzH K Helix-turn-helix domain
NHPPAGDG_00043 5.9e-203 ybcL EGP Major facilitator Superfamily
NHPPAGDG_00045 9.1e-239 J 4Fe-4S single cluster domain
NHPPAGDG_00046 3.3e-275 V CAAX protease self-immunity
NHPPAGDG_00047 6.7e-133 skfE V ABC transporter
NHPPAGDG_00048 8e-247 skfF S ABC transporter
NHPPAGDG_00049 7.8e-91 C HEAT repeats
NHPPAGDG_00050 9.6e-79 txn CO Thioredoxin-like
NHPPAGDG_00051 2.9e-179 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHPPAGDG_00052 1.3e-122 T Transcriptional regulatory protein, C terminal
NHPPAGDG_00053 1.8e-168 T His Kinase A (phospho-acceptor) domain
NHPPAGDG_00055 3.9e-139 KLT Protein tyrosine kinase
NHPPAGDG_00056 7.7e-152 ybdN
NHPPAGDG_00057 3.7e-213 ybdO S Domain of unknown function (DUF4885)
NHPPAGDG_00058 2.4e-256 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NHPPAGDG_00059 1.4e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
NHPPAGDG_00060 4.9e-30 ybxH S Family of unknown function (DUF5370)
NHPPAGDG_00061 3.4e-149 ybxI 3.5.2.6 V beta-lactamase
NHPPAGDG_00062 1.3e-243 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NHPPAGDG_00063 4.9e-41 ybyB
NHPPAGDG_00064 1.5e-289 ybeC E amino acid
NHPPAGDG_00065 2.4e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NHPPAGDG_00066 7.3e-258 glpT G -transporter
NHPPAGDG_00067 1.6e-33 S Protein of unknown function (DUF2651)
NHPPAGDG_00068 2.2e-168 ybfA 3.4.15.5 K FR47-like protein
NHPPAGDG_00069 1e-221 ybfB G COG0477 Permeases of the major facilitator superfamily
NHPPAGDG_00071 0.0 ybfG M Domain of unknown function (DUF1906)
NHPPAGDG_00072 3.7e-160 ybfH EG EamA-like transporter family
NHPPAGDG_00073 8.8e-145 msmR K AraC-like ligand binding domain
NHPPAGDG_00074 2.9e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NHPPAGDG_00075 1.3e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NHPPAGDG_00077 1.6e-163 S Alpha/beta hydrolase family
NHPPAGDG_00078 7e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHPPAGDG_00079 2.7e-85 ybfM S SNARE associated Golgi protein
NHPPAGDG_00080 1.6e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NHPPAGDG_00081 2e-45 ybfN
NHPPAGDG_00082 9e-248 S Erythromycin esterase
NHPPAGDG_00083 1.5e-191 yceA S Belongs to the UPF0176 family
NHPPAGDG_00084 1.4e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHPPAGDG_00085 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPPAGDG_00086 5.7e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHPPAGDG_00087 4.9e-128 K UTRA
NHPPAGDG_00089 2.3e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NHPPAGDG_00090 1.1e-259 mmuP E amino acid
NHPPAGDG_00091 4.6e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NHPPAGDG_00093 2.8e-255 agcS E Sodium alanine symporter
NHPPAGDG_00094 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
NHPPAGDG_00095 4.7e-228 phoQ 2.7.13.3 T Histidine kinase
NHPPAGDG_00096 3.8e-168 glnL T Regulator
NHPPAGDG_00097 1.9e-172 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NHPPAGDG_00098 2e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHPPAGDG_00099 2.2e-254 gudP G COG0477 Permeases of the major facilitator superfamily
NHPPAGDG_00100 5.7e-266 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NHPPAGDG_00101 2.1e-123 ycbG K FCD
NHPPAGDG_00102 1e-68 garD 4.2.1.42, 4.2.1.7 G Altronate
NHPPAGDG_00103 2.9e-78 garD 4.2.1.42, 4.2.1.7 G Altronate
NHPPAGDG_00104 1.1e-95 ycbJ S Macrolide 2'-phosphotransferase
NHPPAGDG_00105 2.4e-53 ycbJ S Macrolide 2'-phosphotransferase
NHPPAGDG_00106 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NHPPAGDG_00107 4.9e-168 eamA1 EG spore germination
NHPPAGDG_00108 6.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_00109 2.7e-77 T PhoQ Sensor
NHPPAGDG_00110 1.5e-77 T PhoQ Sensor
NHPPAGDG_00111 4.1e-167 ycbN V ABC transporter, ATP-binding protein
NHPPAGDG_00112 5.6e-113 S ABC-2 family transporter protein
NHPPAGDG_00113 8.2e-53 ycbP S Protein of unknown function (DUF2512)
NHPPAGDG_00114 3.4e-76 sleB 3.5.1.28 M Cell wall
NHPPAGDG_00115 3.3e-135 ycbR T vWA found in TerF C terminus
NHPPAGDG_00116 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NHPPAGDG_00117 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NHPPAGDG_00118 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHPPAGDG_00119 1.9e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NHPPAGDG_00120 1.6e-202 ycbU E Selenocysteine lyase
NHPPAGDG_00121 1.8e-230 lmrB EGP the major facilitator superfamily
NHPPAGDG_00122 3.1e-101 yxaF K Transcriptional regulator
NHPPAGDG_00123 1.9e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NHPPAGDG_00124 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NHPPAGDG_00125 4.6e-56 S RDD family
NHPPAGDG_00126 2.3e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
NHPPAGDG_00127 5.3e-50 2.7.13.3 T GHKL domain
NHPPAGDG_00128 3.4e-56 2.7.13.3 T GHKL domain
NHPPAGDG_00129 2.5e-124 lytR_2 T LytTr DNA-binding domain
NHPPAGDG_00130 3.4e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NHPPAGDG_00131 4.2e-201 natB CP ABC-2 family transporter protein
NHPPAGDG_00132 3.9e-173 yccK C Aldo keto reductase
NHPPAGDG_00133 3.3e-176 ycdA S Domain of unknown function (DUF5105)
NHPPAGDG_00134 5.3e-275 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_00135 3.1e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_00136 8.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
NHPPAGDG_00137 3.6e-173 S response regulator aspartate phosphatase
NHPPAGDG_00138 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
NHPPAGDG_00139 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NHPPAGDG_00140 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
NHPPAGDG_00141 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NHPPAGDG_00142 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NHPPAGDG_00143 2.6e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPPAGDG_00144 1.9e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NHPPAGDG_00145 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NHPPAGDG_00146 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NHPPAGDG_00147 1.4e-136 terC P Protein of unknown function (DUF475)
NHPPAGDG_00148 0.0 yceG S Putative component of 'biosynthetic module'
NHPPAGDG_00149 9.7e-192 yceH P Belongs to the TelA family
NHPPAGDG_00150 3.3e-217 naiP P Uncharacterised MFS-type transporter YbfB
NHPPAGDG_00151 3.4e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
NHPPAGDG_00152 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NHPPAGDG_00153 5.1e-229 proV 3.6.3.32 E glycine betaine
NHPPAGDG_00154 1.3e-127 opuAB P glycine betaine
NHPPAGDG_00155 1.5e-163 opuAC E glycine betaine
NHPPAGDG_00156 1.2e-216 amhX S amidohydrolase
NHPPAGDG_00157 1.6e-255 ycgA S Membrane
NHPPAGDG_00158 2.8e-46 ycgB
NHPPAGDG_00159 2.6e-269 amyE 3.2.1.1 GH13 G alpha-amylase
NHPPAGDG_00160 1.8e-98 amyE 3.2.1.1 GH13 G alpha-amylase
NHPPAGDG_00161 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHPPAGDG_00162 4.4e-289 lctP C L-lactate permease
NHPPAGDG_00163 1.2e-148 yqcI S YqcI/YcgG family
NHPPAGDG_00164 1.9e-101 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NHPPAGDG_00165 3.1e-37 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NHPPAGDG_00166 1.2e-93 ycgI S Domain of unknown function (DUF1989)
NHPPAGDG_00167 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHPPAGDG_00168 7.5e-106 tmrB S AAA domain
NHPPAGDG_00170 6.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHPPAGDG_00171 2.4e-141 yafE Q ubiE/COQ5 methyltransferase family
NHPPAGDG_00172 4e-173 oxyR3 K LysR substrate binding domain
NHPPAGDG_00173 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NHPPAGDG_00174 8.3e-145 ycgL S Predicted nucleotidyltransferase
NHPPAGDG_00175 5.1e-170 ycgM E Proline dehydrogenase
NHPPAGDG_00176 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NHPPAGDG_00177 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPPAGDG_00178 6.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NHPPAGDG_00179 1.2e-74 K Transcriptional regulator
NHPPAGDG_00180 1.8e-225 pre D plasmid recombination enzyme
NHPPAGDG_00181 3.5e-76 O Hsp20/alpha crystallin family
NHPPAGDG_00182 2.3e-16
NHPPAGDG_00183 2.5e-197 L Replication protein
NHPPAGDG_00184 5.2e-150 ydjN U Involved in the tonB-independent uptake of proteins
NHPPAGDG_00185 4.5e-64 ydjM M Lytic transglycolase
NHPPAGDG_00186 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NHPPAGDG_00187 5.9e-258 iolT EGP Major facilitator Superfamily
NHPPAGDG_00188 5.3e-27 S Ion transport 2 domain protein
NHPPAGDG_00189 4.1e-144 S Ion transport 2 domain protein
NHPPAGDG_00190 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
NHPPAGDG_00191 2.5e-130 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NHPPAGDG_00192 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHPPAGDG_00193 1.3e-112 pspA KT Phage shock protein A
NHPPAGDG_00194 5.8e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NHPPAGDG_00195 2.1e-252 gutA G MFS/sugar transport protein
NHPPAGDG_00196 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
NHPPAGDG_00197 0.0 K NB-ARC domain
NHPPAGDG_00198 3.8e-51
NHPPAGDG_00199 9.3e-59
NHPPAGDG_00201 2.3e-62
NHPPAGDG_00203 8.3e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHPPAGDG_00204 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHPPAGDG_00205 7.9e-129 ydiL S CAAX protease self-immunity
NHPPAGDG_00206 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NHPPAGDG_00207 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHPPAGDG_00208 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NHPPAGDG_00209 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHPPAGDG_00210 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NHPPAGDG_00211 0.0 ydiF S ABC transporter
NHPPAGDG_00212 3e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHPPAGDG_00213 2.8e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NHPPAGDG_00214 1.1e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NHPPAGDG_00215 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NHPPAGDG_00216 1.2e-180 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NHPPAGDG_00218 7.8e-08
NHPPAGDG_00219 6e-44 tnpIS3 L Transposase
NHPPAGDG_00222 1.3e-26 traI 2.5.1.15 U relaxase mobilization nuclease domain protein
NHPPAGDG_00223 3.3e-08
NHPPAGDG_00226 2.7e-180 L Replication protein
NHPPAGDG_00227 8.2e-98 S COG0457 FOG TPR repeat
NHPPAGDG_00231 3e-81 S Protein of unknown function (DUF2690)
NHPPAGDG_00232 2.3e-20 yjfB S Putative motility protein
NHPPAGDG_00233 3.1e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
NHPPAGDG_00234 1.2e-32 T PhoQ Sensor
NHPPAGDG_00235 9.9e-103 yjgB S Domain of unknown function (DUF4309)
NHPPAGDG_00236 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NHPPAGDG_00237 8.3e-72 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NHPPAGDG_00238 1.6e-94 yjgD S Protein of unknown function (DUF1641)
NHPPAGDG_00239 8.7e-07 S Domain of unknown function (DUF4352)
NHPPAGDG_00240 1.9e-115 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NHPPAGDG_00242 6.4e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NHPPAGDG_00243 5e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NHPPAGDG_00244 3.1e-29
NHPPAGDG_00245 1.3e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NHPPAGDG_00246 9.5e-122 ybbM S transport system, permease component
NHPPAGDG_00247 6.4e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NHPPAGDG_00248 5.6e-175 yjlA EG Putative multidrug resistance efflux transporter
NHPPAGDG_00249 1.1e-89 yjlB S Cupin domain
NHPPAGDG_00250 1.2e-65 yjlC S Protein of unknown function (DUF1641)
NHPPAGDG_00251 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NHPPAGDG_00252 5.1e-278 uxaC 5.3.1.12 G glucuronate isomerase
NHPPAGDG_00253 3.7e-249 yjmB G symporter YjmB
NHPPAGDG_00254 4.9e-190 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NHPPAGDG_00255 2.4e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NHPPAGDG_00256 1.4e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NHPPAGDG_00257 3.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPPAGDG_00258 9.1e-226 exuT G Sugar (and other) transporter
NHPPAGDG_00259 6.4e-182 exuR K transcriptional
NHPPAGDG_00260 3.8e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NHPPAGDG_00261 3.2e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NHPPAGDG_00262 1.3e-129 MA20_18170 S membrane transporter protein
NHPPAGDG_00263 2.3e-78 yjoA S DinB family
NHPPAGDG_00264 8.8e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NHPPAGDG_00265 1e-212 S response regulator aspartate phosphatase
NHPPAGDG_00267 1.2e-39 S YCII-related domain
NHPPAGDG_00268 1.6e-158 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NHPPAGDG_00269 1.8e-60 yjqA S Bacterial PH domain
NHPPAGDG_00270 7.9e-111 yjqB S Pfam:DUF867
NHPPAGDG_00271 1.7e-159 ydbD P Catalase
NHPPAGDG_00272 1e-110 xkdA E IrrE N-terminal-like domain
NHPPAGDG_00273 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NHPPAGDG_00275 2.9e-156 xkdB K sequence-specific DNA binding
NHPPAGDG_00276 9.2e-118 xkdC L Bacterial dnaA protein
NHPPAGDG_00279 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NHPPAGDG_00280 2.9e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NHPPAGDG_00281 4.1e-139 xtmA L phage terminase small subunit
NHPPAGDG_00282 3.4e-252 xtmB S phage terminase, large subunit
NHPPAGDG_00283 1.6e-285 yqbA S portal protein
NHPPAGDG_00284 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NHPPAGDG_00285 5.8e-169 xkdG S Phage capsid family
NHPPAGDG_00286 6.2e-61 yqbG S Protein of unknown function (DUF3199)
NHPPAGDG_00287 9.6e-64 yqbH S Domain of unknown function (DUF3599)
NHPPAGDG_00288 6.4e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
NHPPAGDG_00289 1.2e-76 xkdJ
NHPPAGDG_00290 2.5e-256 xkdK S Phage tail sheath C-terminal domain
NHPPAGDG_00291 1e-75 xkdM S Phage tail tube protein
NHPPAGDG_00292 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
NHPPAGDG_00293 0.0 xkdO L Transglycosylase SLT domain
NHPPAGDG_00294 3.7e-122 xkdP S Lysin motif
NHPPAGDG_00295 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NHPPAGDG_00296 2.1e-39 xkdR S Protein of unknown function (DUF2577)
NHPPAGDG_00297 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NHPPAGDG_00298 5.1e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NHPPAGDG_00299 2.4e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NHPPAGDG_00300 4.3e-40
NHPPAGDG_00301 0.0
NHPPAGDG_00302 6e-35 xkdW S XkdW protein
NHPPAGDG_00303 1.7e-23 xkdX
NHPPAGDG_00304 5.8e-152 xepA
NHPPAGDG_00305 1.8e-38 xhlA S Haemolysin XhlA
NHPPAGDG_00306 7.9e-39 xhlB S SPP1 phage holin
NHPPAGDG_00307 3.3e-161 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPPAGDG_00308 6.7e-23 spoIISB S Stage II sporulation protein SB
NHPPAGDG_00309 5.2e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NHPPAGDG_00310 7.6e-175 pit P phosphate transporter
NHPPAGDG_00311 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NHPPAGDG_00312 1.5e-239 steT E amino acid
NHPPAGDG_00313 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NHPPAGDG_00314 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHPPAGDG_00315 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPPAGDG_00317 3.2e-213 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHPPAGDG_00318 2.6e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NHPPAGDG_00319 5.1e-153 dppA E D-aminopeptidase
NHPPAGDG_00320 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPPAGDG_00321 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPPAGDG_00322 1.1e-186 dppD P Belongs to the ABC transporter superfamily
NHPPAGDG_00323 0.0 dppE E ABC transporter substrate-binding protein
NHPPAGDG_00325 8.4e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NHPPAGDG_00326 8.3e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NHPPAGDG_00327 4.4e-166 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NHPPAGDG_00328 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
NHPPAGDG_00329 7.6e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
NHPPAGDG_00330 1.7e-159 ykgA E Amidinotransferase
NHPPAGDG_00331 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NHPPAGDG_00332 2.4e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHPPAGDG_00333 2.6e-08
NHPPAGDG_00334 2.3e-128 ykjA S Protein of unknown function (DUF421)
NHPPAGDG_00335 9.7e-97 ykkA S Protein of unknown function (DUF664)
NHPPAGDG_00336 1.2e-96 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHPPAGDG_00337 1.3e-54 ykkC P Multidrug resistance protein
NHPPAGDG_00338 9.1e-50 ykkD P Multidrug resistance protein
NHPPAGDG_00339 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NHPPAGDG_00340 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHPPAGDG_00341 2.4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHPPAGDG_00343 4.8e-70 ohrA O Organic hydroperoxide resistance protein
NHPPAGDG_00344 3.9e-75 ohrR K COG1846 Transcriptional regulators
NHPPAGDG_00345 8.4e-72 ohrB O Organic hydroperoxide resistance protein
NHPPAGDG_00346 5.5e-83 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NHPPAGDG_00347 2.2e-100 5.4.2.11 G Belongs to the phosphoglycerate mutase family
NHPPAGDG_00348 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHPPAGDG_00349 1.5e-175 isp O Belongs to the peptidase S8 family
NHPPAGDG_00350 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHPPAGDG_00351 7.6e-135 ykoC P Cobalt transport protein
NHPPAGDG_00352 2e-283 P ABC transporter, ATP-binding protein
NHPPAGDG_00353 2e-98 ykoE S ABC-type cobalt transport system, permease component
NHPPAGDG_00354 9.7e-109 ykoF S YKOF-related Family
NHPPAGDG_00355 9.3e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_00356 1.8e-240 ykoH 2.7.13.3 T Histidine kinase
NHPPAGDG_00357 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
NHPPAGDG_00358 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
NHPPAGDG_00361 2.2e-222 mgtE P Acts as a magnesium transporter
NHPPAGDG_00362 1.4e-53 tnrA K transcriptional
NHPPAGDG_00363 5.9e-18
NHPPAGDG_00364 6.9e-26 ykoL
NHPPAGDG_00365 1.3e-81 mhqR K transcriptional
NHPPAGDG_00366 3.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NHPPAGDG_00367 6.3e-97 ykoP G polysaccharide deacetylase
NHPPAGDG_00368 6e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NHPPAGDG_00369 0.0 ykoS
NHPPAGDG_00370 3.1e-184 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPPAGDG_00371 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NHPPAGDG_00372 1.5e-158 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NHPPAGDG_00373 2.5e-272 ydcR 2.7.7.65 T Diguanylate cyclase
NHPPAGDG_00374 9.6e-161 ydcR 2.7.7.65 T Diguanylate cyclase
NHPPAGDG_00375 1.5e-107 ykoX S membrane-associated protein
NHPPAGDG_00376 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NHPPAGDG_00377 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPPAGDG_00378 5e-114 rsgI S Anti-sigma factor N-terminus
NHPPAGDG_00379 1.9e-26 sspD S small acid-soluble spore protein
NHPPAGDG_00380 1.9e-124 ykrK S Domain of unknown function (DUF1836)
NHPPAGDG_00381 3.5e-155 htpX O Belongs to the peptidase M48B family
NHPPAGDG_00382 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NHPPAGDG_00383 1.2e-10 ydfR S Protein of unknown function (DUF421)
NHPPAGDG_00384 4.1e-18 ykzE
NHPPAGDG_00385 1.6e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NHPPAGDG_00386 0.0 kinE 2.7.13.3 T Histidine kinase
NHPPAGDG_00387 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHPPAGDG_00389 8.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NHPPAGDG_00390 2.2e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NHPPAGDG_00391 3.3e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHPPAGDG_00392 3.4e-230 mtnE 2.6.1.83 E Aminotransferase
NHPPAGDG_00393 1.1e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NHPPAGDG_00394 3.5e-134 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NHPPAGDG_00395 2.3e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NHPPAGDG_00396 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NHPPAGDG_00397 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
NHPPAGDG_00398 6.4e-09 S Spo0E like sporulation regulatory protein
NHPPAGDG_00399 1.1e-61 eag
NHPPAGDG_00400 4.5e-272 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NHPPAGDG_00401 1.3e-75 ykvE K transcriptional
NHPPAGDG_00402 1.5e-122 motB N Flagellar motor protein
NHPPAGDG_00403 8.6e-137 motA N flagellar motor
NHPPAGDG_00404 0.0 clpE O Belongs to the ClpA ClpB family
NHPPAGDG_00405 2.4e-179 ykvI S membrane
NHPPAGDG_00406 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHPPAGDG_00407 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NHPPAGDG_00408 2.4e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NHPPAGDG_00409 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NHPPAGDG_00410 2e-61 ykvN K Transcriptional regulator
NHPPAGDG_00411 5.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
NHPPAGDG_00412 2.1e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
NHPPAGDG_00413 3.5e-35 3.5.1.104 M LysM domain
NHPPAGDG_00414 3.1e-162 G Glycosyl hydrolases family 18
NHPPAGDG_00415 2.8e-45 ykvR S Protein of unknown function (DUF3219)
NHPPAGDG_00416 6e-25 ykvS S protein conserved in bacteria
NHPPAGDG_00417 2.8e-28
NHPPAGDG_00418 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NHPPAGDG_00419 1.3e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPPAGDG_00420 1.8e-89 stoA CO thiol-disulfide
NHPPAGDG_00421 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NHPPAGDG_00422 1e-09
NHPPAGDG_00423 1.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NHPPAGDG_00424 9e-48 ykvZ 5.1.1.1 K Transcriptional regulator
NHPPAGDG_00425 8.3e-99 ykvZ 5.1.1.1 K Transcriptional regulator
NHPPAGDG_00427 7.6e-128 glcT K antiterminator
NHPPAGDG_00428 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPPAGDG_00429 2.1e-39 ptsH G phosphocarrier protein HPr
NHPPAGDG_00430 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHPPAGDG_00431 7.2e-39 splA S Transcriptional regulator
NHPPAGDG_00432 1.4e-200 splB 4.1.99.14 L Spore photoproduct lyase
NHPPAGDG_00433 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPPAGDG_00434 4.4e-259 mcpC NT chemotaxis protein
NHPPAGDG_00435 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NHPPAGDG_00439 5.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_00440 0.0 vicK 2.7.13.3 T Histidine kinase
NHPPAGDG_00441 7.5e-258 yycH S protein conserved in bacteria
NHPPAGDG_00442 7.3e-155 yycI S protein conserved in bacteria
NHPPAGDG_00443 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NHPPAGDG_00444 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHPPAGDG_00445 7.2e-17 S Peptidase propeptide and YPEB domain
NHPPAGDG_00446 1.2e-73 S Peptidase propeptide and YPEB domain
NHPPAGDG_00447 4.5e-94 K PFAM response regulator receiver
NHPPAGDG_00448 1.1e-171 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
NHPPAGDG_00449 3.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NHPPAGDG_00450 7.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NHPPAGDG_00451 2.8e-260 rocE E amino acid
NHPPAGDG_00452 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NHPPAGDG_00454 1.5e-187 S aspartate phosphatase
NHPPAGDG_00455 1.9e-83 yycN 2.3.1.128 K Acetyltransferase
NHPPAGDG_00456 1.9e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NHPPAGDG_00457 9.6e-206 yycP
NHPPAGDG_00458 3.3e-20 yycQ S Protein of unknown function (DUF2651)
NHPPAGDG_00460 3.7e-232 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NHPPAGDG_00461 1.4e-63
NHPPAGDG_00462 1.1e-09 S YyzF-like protein
NHPPAGDG_00463 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHPPAGDG_00464 1.7e-225 L Protein of unknown function (DUF2813)
NHPPAGDG_00465 4e-159 pcrA1 3.6.4.12 L UvrD/REP helicase N-terminal domain
NHPPAGDG_00466 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NHPPAGDG_00467 5.9e-109 prrC P ABC transporter
NHPPAGDG_00468 1.8e-117 S ABC-2 family transporter protein
NHPPAGDG_00469 1.7e-12
NHPPAGDG_00470 9.6e-124 yydK K Transcriptional regulator
NHPPAGDG_00471 2.4e-19 bglF G phosphotransferase system
NHPPAGDG_00472 7e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHPPAGDG_00473 1.2e-285 ahpF O Alkyl hydroperoxide reductase
NHPPAGDG_00474 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NHPPAGDG_00475 3.6e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHPPAGDG_00476 5.9e-231 gntP EG COG2610 H gluconate symporter and related permeases
NHPPAGDG_00477 1.2e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NHPPAGDG_00478 2.1e-126 gntR K transcriptional
NHPPAGDG_00479 2.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NHPPAGDG_00480 2e-191 yxaB GM Polysaccharide pyruvyl transferase
NHPPAGDG_00481 2.6e-118 yxaC M effector of murein hydrolase
NHPPAGDG_00482 1.9e-44 S LrgA family
NHPPAGDG_00483 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NHPPAGDG_00484 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPPAGDG_00485 7.1e-101 yxaF K Transcriptional regulator
NHPPAGDG_00486 1e-190 yxaG 1.13.11.24 S AraC-like ligand binding domain
NHPPAGDG_00487 1e-221 P Protein of unknown function (DUF418)
NHPPAGDG_00488 1.4e-75 yxaI S membrane protein domain
NHPPAGDG_00489 1.6e-62 S Family of unknown function (DUF5391)
NHPPAGDG_00490 2.8e-83 S PQQ-like domain
NHPPAGDG_00491 1.5e-11 yxaI S membrane protein domain
NHPPAGDG_00492 1.3e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NHPPAGDG_00493 2.7e-208 yxbF K Bacterial regulatory proteins, tetR family
NHPPAGDG_00494 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
NHPPAGDG_00496 0.0 htpG O Molecular chaperone. Has ATPase activity
NHPPAGDG_00497 2.8e-244 csbC EGP Major facilitator Superfamily
NHPPAGDG_00502 7.8e-08
NHPPAGDG_00508 2e-08
NHPPAGDG_00512 1.2e-238 L COG3328 Transposase and inactivated derivatives
NHPPAGDG_00513 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NHPPAGDG_00514 1.4e-45 L transposase activity
NHPPAGDG_00518 2e-08
NHPPAGDG_00525 1.3e-09
NHPPAGDG_00526 7.8e-08
NHPPAGDG_00535 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NHPPAGDG_00536 5.2e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NHPPAGDG_00537 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NHPPAGDG_00538 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NHPPAGDG_00539 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHPPAGDG_00540 4.5e-40 tspO T membrane
NHPPAGDG_00541 9.7e-205 cotI S Spore coat protein
NHPPAGDG_00542 5.9e-216 cotSA M Glycosyl transferases group 1
NHPPAGDG_00543 8.2e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
NHPPAGDG_00545 1.8e-226 ytcC M Glycosyltransferase Family 4
NHPPAGDG_00546 5.9e-177 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NHPPAGDG_00547 8.3e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHPPAGDG_00548 2.3e-153 galU 2.7.7.9 M Nucleotidyl transferase
NHPPAGDG_00549 7.4e-132 dksA T COG1734 DnaK suppressor protein
NHPPAGDG_00550 2.7e-271 menF 5.4.4.2 HQ Isochorismate synthase
NHPPAGDG_00551 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NHPPAGDG_00552 1.7e-151 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NHPPAGDG_00553 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NHPPAGDG_00554 1.3e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NHPPAGDG_00555 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NHPPAGDG_00556 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
NHPPAGDG_00557 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NHPPAGDG_00558 9.7e-117 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NHPPAGDG_00559 1.4e-96 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NHPPAGDG_00560 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NHPPAGDG_00561 4.3e-24 S Domain of Unknown Function (DUF1540)
NHPPAGDG_00562 5.2e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NHPPAGDG_00563 3.4e-247 cydA 1.10.3.14 C oxidase, subunit
NHPPAGDG_00564 6.1e-41 rpmE2 J Ribosomal protein L31
NHPPAGDG_00565 2.2e-102 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NHPPAGDG_00566 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHPPAGDG_00567 1.1e-72 ytkA S YtkA-like
NHPPAGDG_00569 2.1e-76 dps P Belongs to the Dps family
NHPPAGDG_00570 1.7e-61 ytkC S Bacteriophage holin family
NHPPAGDG_00571 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NHPPAGDG_00572 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NHPPAGDG_00573 1.4e-144 ytlC P ABC transporter
NHPPAGDG_00574 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NHPPAGDG_00575 1.1e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NHPPAGDG_00576 1.6e-38 ytmB S Protein of unknown function (DUF2584)
NHPPAGDG_00577 3.3e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NHPPAGDG_00578 4.7e-224 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHPPAGDG_00579 0.0 asnB 6.3.5.4 E Asparagine synthase
NHPPAGDG_00580 2.3e-249 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NHPPAGDG_00581 2.7e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NHPPAGDG_00582 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NHPPAGDG_00583 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NHPPAGDG_00584 7.4e-106 ytqB J Putative rRNA methylase
NHPPAGDG_00585 8.1e-190 yhcC S Fe-S oxidoreductase
NHPPAGDG_00586 1.5e-40 ytzC S Protein of unknown function (DUF2524)
NHPPAGDG_00588 5.1e-66 ytrA K GntR family transcriptional regulator
NHPPAGDG_00589 6e-160 ytrB P abc transporter atp-binding protein
NHPPAGDG_00590 4.4e-151 P ABC-2 family transporter protein
NHPPAGDG_00591 2.1e-145
NHPPAGDG_00592 9.1e-127 ytrE V ABC transporter, ATP-binding protein
NHPPAGDG_00593 3.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NHPPAGDG_00594 1.2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_00595 5.6e-186 T PhoQ Sensor
NHPPAGDG_00596 1.1e-138 bceA V ABC transporter, ATP-binding protein
NHPPAGDG_00597 0.0 bceB V ABC transporter (permease)
NHPPAGDG_00598 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NHPPAGDG_00599 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHPPAGDG_00600 4.1e-30 yazB K transcriptional
NHPPAGDG_00601 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHPPAGDG_00602 2.2e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHPPAGDG_00603 1.9e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHPPAGDG_00604 1.9e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NHPPAGDG_00605 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NHPPAGDG_00606 2.8e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHPPAGDG_00607 1.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NHPPAGDG_00608 1.3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NHPPAGDG_00609 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHPPAGDG_00610 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NHPPAGDG_00611 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHPPAGDG_00612 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NHPPAGDG_00613 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHPPAGDG_00614 1.8e-184 KLT serine threonine protein kinase
NHPPAGDG_00615 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NHPPAGDG_00616 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NHPPAGDG_00619 1.1e-16 ydhU P Manganese containing catalase
NHPPAGDG_00620 1.8e-78 ydhU P Catalase
NHPPAGDG_00621 1.2e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NHPPAGDG_00622 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHPPAGDG_00623 7.5e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NHPPAGDG_00624 1.1e-132 ydhQ K UTRA
NHPPAGDG_00625 8.1e-284 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHPPAGDG_00626 7.1e-181 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHPPAGDG_00627 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NHPPAGDG_00628 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NHPPAGDG_00629 4.6e-200 pbuE EGP Major facilitator Superfamily
NHPPAGDG_00630 9.4e-98 ydhK M Protein of unknown function (DUF1541)
NHPPAGDG_00631 6.2e-182 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NHPPAGDG_00632 8.6e-84 K Acetyltransferase (GNAT) domain
NHPPAGDG_00634 1.4e-65 frataxin S Domain of unknown function (DU1801)
NHPPAGDG_00635 5.2e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NHPPAGDG_00636 1.9e-124
NHPPAGDG_00637 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NHPPAGDG_00638 2.2e-243 ydhD M Glycosyl hydrolase
NHPPAGDG_00639 6.5e-122 ydhC K FCD
NHPPAGDG_00640 1.2e-121 ydhB S membrane transporter protein
NHPPAGDG_00641 2.2e-208 tcaB EGP Major facilitator Superfamily
NHPPAGDG_00642 7.1e-69 ydgJ K Winged helix DNA-binding domain
NHPPAGDG_00643 1e-113 drgA C nitroreductase
NHPPAGDG_00644 0.0 ydgH S drug exporters of the RND superfamily
NHPPAGDG_00645 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
NHPPAGDG_00646 8.7e-90 dinB S DinB family
NHPPAGDG_00647 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NHPPAGDG_00648 6.5e-99 expZ S ABC transporter
NHPPAGDG_00649 1.8e-190 expZ S ABC transporter
NHPPAGDG_00650 1.7e-84 yycN 2.3.1.128 K Acetyltransferase
NHPPAGDG_00651 3.4e-50 S DoxX-like family
NHPPAGDG_00652 2e-98 K Bacterial regulatory proteins, tetR family
NHPPAGDG_00653 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NHPPAGDG_00654 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
NHPPAGDG_00655 1.9e-74 cotP O Belongs to the small heat shock protein (HSP20) family
NHPPAGDG_00656 1.5e-121 ydfS S Protein of unknown function (DUF421)
NHPPAGDG_00657 1e-28 ydfR S Protein of unknown function (DUF421)
NHPPAGDG_00658 1.9e-56 ydfR S Protein of unknown function (DUF421)
NHPPAGDG_00660 6.3e-29
NHPPAGDG_00661 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NHPPAGDG_00662 1.6e-55 traF CO Thioredoxin
NHPPAGDG_00663 8.8e-63 mhqP S DoxX
NHPPAGDG_00664 1.7e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NHPPAGDG_00665 8.4e-108 ydfN C nitroreductase
NHPPAGDG_00666 2.9e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHPPAGDG_00669 5.4e-13
NHPPAGDG_00670 5.6e-11 S response regulator aspartate phosphatase
NHPPAGDG_00672 6.6e-145 K Bacterial transcription activator, effector binding domain
NHPPAGDG_00673 8.5e-117 S Protein of unknown function (DUF554)
NHPPAGDG_00674 0.0 ydfJ S drug exporters of the RND superfamily
NHPPAGDG_00675 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPPAGDG_00676 3.2e-177 ydfH 2.7.13.3 T Histidine kinase
NHPPAGDG_00678 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHPPAGDG_00679 7.8e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NHPPAGDG_00680 5e-116 ydfE S Flavin reductase like domain
NHPPAGDG_00681 7.9e-274 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPPAGDG_00682 5.9e-158 ydfC EG EamA-like transporter family
NHPPAGDG_00683 6.5e-142 ydfB J GNAT acetyltransferase
NHPPAGDG_00684 3.5e-73 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NHPPAGDG_00685 2.9e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NHPPAGDG_00686 2.8e-57 arsR K transcriptional
NHPPAGDG_00687 1.2e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NHPPAGDG_00688 3e-56 K HxlR-like helix-turn-helix
NHPPAGDG_00689 1.6e-105 ydeN S Serine hydrolase
NHPPAGDG_00690 1.2e-73 maoC I N-terminal half of MaoC dehydratase
NHPPAGDG_00691 6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPPAGDG_00692 7e-153 ydeK EG -transporter
NHPPAGDG_00693 8.8e-85 K Transcriptional regulator C-terminal region
NHPPAGDG_00694 1.8e-14 ptsH G PTS HPr component phosphorylation site
NHPPAGDG_00695 2.6e-31 S SNARE associated Golgi protein
NHPPAGDG_00696 3e-111
NHPPAGDG_00697 6.6e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NHPPAGDG_00698 2.3e-154 ydeG EGP Major facilitator superfamily
NHPPAGDG_00699 1.5e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPPAGDG_00700 8.4e-162 ydeE K AraC family transcriptional regulator
NHPPAGDG_00701 6.3e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHPPAGDG_00702 3.2e-161 rhaS5 K AraC-like ligand binding domain
NHPPAGDG_00703 4.6e-35 ydzE EG spore germination
NHPPAGDG_00704 3e-78 carD K Transcription factor
NHPPAGDG_00705 2.5e-29 cspL K Cold shock
NHPPAGDG_00706 1.3e-190 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NHPPAGDG_00707 3.6e-39
NHPPAGDG_00708 3.4e-33 K Helix-turn-helix XRE-family like proteins
NHPPAGDG_00709 9.6e-11
NHPPAGDG_00710 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHPPAGDG_00711 5.2e-77 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPPAGDG_00712 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NHPPAGDG_00713 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NHPPAGDG_00715 1.9e-15 yycC K YycC-like protein
NHPPAGDG_00716 2.1e-219 yeaN P COG2807 Cyanate permease
NHPPAGDG_00717 6.5e-82 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHPPAGDG_00718 9.5e-265 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHPPAGDG_00719 1.9e-72 rplI J binds to the 23S rRNA
NHPPAGDG_00720 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NHPPAGDG_00721 8.3e-160 yybS S membrane
NHPPAGDG_00723 4e-14 cotF M Spore coat protein
NHPPAGDG_00724 1.7e-66 ydeP3 K Transcriptional regulator
NHPPAGDG_00725 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NHPPAGDG_00726 2.3e-33
NHPPAGDG_00727 3.2e-27
NHPPAGDG_00729 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NHPPAGDG_00730 3.7e-110 K TipAS antibiotic-recognition domain
NHPPAGDG_00731 3.4e-122
NHPPAGDG_00732 8.6e-66 yybH S SnoaL-like domain
NHPPAGDG_00733 6.9e-121 yybG S Pentapeptide repeat-containing protein
NHPPAGDG_00734 2e-214 ynfM EGP Major facilitator Superfamily
NHPPAGDG_00735 2.6e-163 yybE K Transcriptional regulator
NHPPAGDG_00736 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
NHPPAGDG_00737 3.6e-74 yybC
NHPPAGDG_00738 1.9e-126 S Metallo-beta-lactamase superfamily
NHPPAGDG_00739 5.6e-77 yybA 2.3.1.57 K transcriptional
NHPPAGDG_00740 4.2e-69 yjcF S Acetyltransferase (GNAT) domain
NHPPAGDG_00741 6.5e-97 yyaS S Membrane
NHPPAGDG_00742 6.4e-93 yyaR K Acetyltransferase (GNAT) domain
NHPPAGDG_00743 2.4e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NHPPAGDG_00744 3.1e-101 S Type II restriction endonuclease EcoO109I
NHPPAGDG_00745 3.3e-218 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
NHPPAGDG_00746 1.3e-23 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NHPPAGDG_00747 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NHPPAGDG_00748 4.4e-166 yyaK S CAAX protease self-immunity
NHPPAGDG_00749 1.8e-243 EGP Major facilitator superfamily
NHPPAGDG_00750 9.3e-90 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NHPPAGDG_00751 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPPAGDG_00752 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NHPPAGDG_00753 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
NHPPAGDG_00754 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHPPAGDG_00755 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHPPAGDG_00756 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NHPPAGDG_00757 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHPPAGDG_00758 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHPPAGDG_00759 2.3e-33 yyzM S protein conserved in bacteria
NHPPAGDG_00760 8.1e-177 yyaD S Membrane
NHPPAGDG_00761 3.6e-111 yyaC S Sporulation protein YyaC
NHPPAGDG_00762 2.1e-149 spo0J K Belongs to the ParB family
NHPPAGDG_00763 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NHPPAGDG_00764 4.1e-72 S Bacterial PH domain
NHPPAGDG_00765 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NHPPAGDG_00766 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NHPPAGDG_00767 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHPPAGDG_00768 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHPPAGDG_00769 6.5e-108 jag S single-stranded nucleic acid binding R3H
NHPPAGDG_00770 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHPPAGDG_00771 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHPPAGDG_00772 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHPPAGDG_00773 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHPPAGDG_00774 2.4e-33 yaaA S S4 domain
NHPPAGDG_00775 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHPPAGDG_00776 1.8e-37 yaaB S Domain of unknown function (DUF370)
NHPPAGDG_00777 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHPPAGDG_00778 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHPPAGDG_00779 1.2e-52 flaG N flagellar protein FlaG
NHPPAGDG_00780 7.7e-248 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NHPPAGDG_00781 1.9e-68 fliS N flagellar protein FliS
NHPPAGDG_00782 1.9e-08 fliT S bacterial-type flagellum organization
NHPPAGDG_00783 4.6e-51
NHPPAGDG_00784 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHPPAGDG_00785 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHPPAGDG_00786 1.8e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHPPAGDG_00787 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NHPPAGDG_00788 2e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
NHPPAGDG_00789 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NHPPAGDG_00790 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NHPPAGDG_00791 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NHPPAGDG_00792 5.3e-56 swrA S Swarming motility protein
NHPPAGDG_00793 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHPPAGDG_00794 7.9e-228 yvkA EGP Major facilitator Superfamily
NHPPAGDG_00795 1e-99 yvkB K Transcriptional regulator
NHPPAGDG_00796 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NHPPAGDG_00797 1.2e-30 csbA S protein conserved in bacteria
NHPPAGDG_00798 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHPPAGDG_00799 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHPPAGDG_00800 5.9e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NHPPAGDG_00801 2.4e-170 ywtF K Transcriptional regulator
NHPPAGDG_00802 2.5e-245 ywtG EGP Major facilitator Superfamily
NHPPAGDG_00803 1.4e-206 gerAC S Spore germination protein
NHPPAGDG_00804 5.8e-192 gerBB E Spore germination protein
NHPPAGDG_00805 2.2e-260 gerBA EG Spore germination protein
NHPPAGDG_00806 4.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NHPPAGDG_00807 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHPPAGDG_00808 3.5e-260
NHPPAGDG_00809 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NHPPAGDG_00810 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NHPPAGDG_00811 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NHPPAGDG_00812 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
NHPPAGDG_00813 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NHPPAGDG_00814 1.1e-150 tagG GM Transport permease protein
NHPPAGDG_00815 2.2e-277 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NHPPAGDG_00816 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHPPAGDG_00818 1.4e-256 ggaA M Glycosyltransferase like family 2
NHPPAGDG_00819 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NHPPAGDG_00820 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHPPAGDG_00821 1e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHPPAGDG_00822 4e-162 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NHPPAGDG_00823 6e-38
NHPPAGDG_00824 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NHPPAGDG_00825 5.6e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPPAGDG_00826 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NHPPAGDG_00827 5.7e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPPAGDG_00828 1.7e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NHPPAGDG_00829 7.6e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHPPAGDG_00830 2.7e-261 tuaE M Teichuronic acid biosynthesis protein
NHPPAGDG_00831 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
NHPPAGDG_00832 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
NHPPAGDG_00833 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NHPPAGDG_00834 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NHPPAGDG_00835 6e-163 yvhJ K Transcriptional regulator
NHPPAGDG_00836 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NHPPAGDG_00837 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NHPPAGDG_00838 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPPAGDG_00839 7.3e-155 degV S protein conserved in bacteria
NHPPAGDG_00840 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NHPPAGDG_00841 5.7e-46 comFB S Late competence development protein ComFB
NHPPAGDG_00842 1.5e-124 comFC S Phosphoribosyl transferase domain
NHPPAGDG_00843 4.6e-73 yvyF S flagellar protein
NHPPAGDG_00844 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
NHPPAGDG_00845 9.2e-78 flgN NOU FlgN protein
NHPPAGDG_00846 5.6e-262 flgK N flagellar hook-associated protein
NHPPAGDG_00847 7.8e-155 flgL N Belongs to the bacterial flagellin family
NHPPAGDG_00848 5.7e-50 yviE
NHPPAGDG_00849 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NHPPAGDG_00850 1.7e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NHPPAGDG_00851 1.3e-42 L Integrase core domain
NHPPAGDG_00852 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NHPPAGDG_00853 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NHPPAGDG_00854 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHPPAGDG_00855 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHPPAGDG_00856 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHPPAGDG_00857 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHPPAGDG_00858 1.4e-95 yaaI Q COG1335 Amidases related to nicotinamidase
NHPPAGDG_00859 2.1e-209 yaaH M Glycoside Hydrolase Family
NHPPAGDG_00860 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NHPPAGDG_00861 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NHPPAGDG_00862 1.3e-09
NHPPAGDG_00863 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHPPAGDG_00864 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NHPPAGDG_00865 2.8e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NHPPAGDG_00866 7.5e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NHPPAGDG_00867 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NHPPAGDG_00868 2.1e-179 yaaC S YaaC-like Protein
NHPPAGDG_00869 5.9e-97 S Protein of unknown function (DUF421)
NHPPAGDG_00870 5.4e-286 clsA_1 I PLD-like domain
NHPPAGDG_00871 1.2e-70 S Protein of unknown function (DUF421)
NHPPAGDG_00872 2.8e-07 S Protein of unknown function (DUF421)
NHPPAGDG_00873 1.2e-149 yetF1 S membrane
NHPPAGDG_00874 5.8e-29 S Protein of unknown function (DUF1657)
NHPPAGDG_00875 2.5e-56 spoVAE S stage V sporulation protein
NHPPAGDG_00876 1e-195 spoVAD I Stage V sporulation protein AD
NHPPAGDG_00877 2.6e-80 spoVAC S stage V sporulation protein AC
NHPPAGDG_00878 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHPPAGDG_00879 6e-26 S Protein of unknown function (DUF1657)
NHPPAGDG_00880 3.8e-159 rlmA 2.1.1.187 Q Methyltransferase domain
NHPPAGDG_00881 9.8e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NHPPAGDG_00882 9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHPPAGDG_00883 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NHPPAGDG_00884 4.8e-26 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NHPPAGDG_00885 1.8e-90 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NHPPAGDG_00886 1.8e-217 yxjG 2.1.1.14 E Methionine synthase
NHPPAGDG_00887 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
NHPPAGDG_00888 1.6e-85 yxjI S LURP-one-related
NHPPAGDG_00891 3.4e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NHPPAGDG_00892 3.2e-113 K helix_turn_helix, Lux Regulon
NHPPAGDG_00893 3.3e-188 yxjM T Signal transduction histidine kinase
NHPPAGDG_00894 2e-77 S Protein of unknown function (DUF1453)
NHPPAGDG_00895 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NHPPAGDG_00896 2.4e-73 yxkC S Domain of unknown function (DUF4352)
NHPPAGDG_00897 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHPPAGDG_00898 6.3e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHPPAGDG_00899 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
NHPPAGDG_00900 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NHPPAGDG_00901 3.3e-155 yxkH G Polysaccharide deacetylase
NHPPAGDG_00903 1.8e-309 3.4.24.84 O Peptidase family M48
NHPPAGDG_00904 6.1e-228 cimH C COG3493 Na citrate symporter
NHPPAGDG_00905 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
NHPPAGDG_00906 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NHPPAGDG_00907 1.2e-310 cydD V ATP-binding
NHPPAGDG_00908 0.0 cydD V ATP-binding protein
NHPPAGDG_00909 6.5e-156 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHPPAGDG_00910 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NHPPAGDG_00911 1.8e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_00912 3.9e-48 yxlC S Family of unknown function (DUF5345)
NHPPAGDG_00913 1.3e-28
NHPPAGDG_00914 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NHPPAGDG_00915 2.4e-147 yxlF V ABC transporter, ATP-binding protein
NHPPAGDG_00916 1.5e-98 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHPPAGDG_00917 3.8e-210 yxlH EGP Major facilitator Superfamily
NHPPAGDG_00918 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NHPPAGDG_00919 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NHPPAGDG_00920 1.1e-19 yxzF
NHPPAGDG_00921 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NHPPAGDG_00922 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NHPPAGDG_00923 4.5e-247 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHPPAGDG_00924 5.6e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NHPPAGDG_00925 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NHPPAGDG_00926 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NHPPAGDG_00927 6.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPPAGDG_00928 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHPPAGDG_00929 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPPAGDG_00930 2.7e-232 dltB M membrane protein involved in D-alanine export
NHPPAGDG_00931 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPPAGDG_00932 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NHPPAGDG_00933 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NHPPAGDG_00934 1e-130 ynfM EGP Major facilitator Superfamily
NHPPAGDG_00935 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
NHPPAGDG_00936 5.3e-92 K Helix-turn-helix XRE-family like proteins
NHPPAGDG_00937 8.3e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NHPPAGDG_00938 2.2e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHPPAGDG_00939 8.1e-88 ywaE K Transcriptional regulator
NHPPAGDG_00940 4.6e-126 ywaF S Integral membrane protein
NHPPAGDG_00941 4.5e-168 gspA M General stress
NHPPAGDG_00942 1.2e-152 sacY K transcriptional antiterminator
NHPPAGDG_00943 1.2e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPPAGDG_00944 2e-269 epr 3.4.21.62 O Belongs to the peptidase S8 family
NHPPAGDG_00945 3.3e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHPPAGDG_00946 8.3e-125 ywbB S Protein of unknown function (DUF2711)
NHPPAGDG_00947 2.9e-66 ywbC 4.4.1.5 E glyoxalase
NHPPAGDG_00948 7e-220 ywbD 2.1.1.191 J Methyltransferase
NHPPAGDG_00949 1.2e-26 ywbE S Uncharacterized conserved protein (DUF2196)
NHPPAGDG_00950 2.2e-205 ywbF EGP Major facilitator Superfamily
NHPPAGDG_00951 2.3e-111 ywbG M effector of murein hydrolase
NHPPAGDG_00952 1.9e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NHPPAGDG_00953 8.1e-152 ywbI K Transcriptional regulator
NHPPAGDG_00954 2.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NHPPAGDG_00955 5.5e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NHPPAGDG_00956 2.5e-248 P COG0672 High-affinity Fe2 Pb2 permease
NHPPAGDG_00957 2.1e-184 ycdO P periplasmic lipoprotein involved in iron transport
NHPPAGDG_00958 2.5e-223 ywbN P Dyp-type peroxidase family protein
NHPPAGDG_00959 2.4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NHPPAGDG_00960 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPPAGDG_00961 1.7e-48 ywcB S Protein of unknown function, DUF485
NHPPAGDG_00963 1.1e-121 ywcC K transcriptional regulator
NHPPAGDG_00964 9.5e-60 gtcA S GtrA-like protein
NHPPAGDG_00965 4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHPPAGDG_00966 3.3e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NHPPAGDG_00967 1e-35 ywzA S membrane
NHPPAGDG_00968 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NHPPAGDG_00969 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHPPAGDG_00970 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NHPPAGDG_00971 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NHPPAGDG_00972 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NHPPAGDG_00973 2.9e-202 rodA D Belongs to the SEDS family
NHPPAGDG_00974 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NHPPAGDG_00975 9.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPPAGDG_00976 0.0 vpr O Belongs to the peptidase S8 family
NHPPAGDG_00978 7e-150 sacT K transcriptional antiterminator
NHPPAGDG_00979 5.7e-138 focA P Formate/nitrite transporter
NHPPAGDG_00980 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPPAGDG_00981 2.5e-288 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NHPPAGDG_00982 1e-27 ywdA
NHPPAGDG_00983 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NHPPAGDG_00984 1.3e-57 pex K Transcriptional regulator PadR-like family
NHPPAGDG_00985 1.4e-113 ywdD
NHPPAGDG_00987 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
NHPPAGDG_00988 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHPPAGDG_00989 2.9e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NHPPAGDG_00990 1.7e-48 ywdI S Family of unknown function (DUF5327)
NHPPAGDG_00991 2e-172 ywdJ F Xanthine uracil
NHPPAGDG_00992 1.1e-53 ywdJ F Xanthine uracil
NHPPAGDG_00993 4.3e-59 ywdK S small membrane protein
NHPPAGDG_00994 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NHPPAGDG_00995 1.8e-144 spsA M Spore Coat
NHPPAGDG_00996 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
NHPPAGDG_00997 1.6e-221 spsC E Belongs to the DegT DnrJ EryC1 family
NHPPAGDG_00998 3.7e-162 spsD 2.3.1.210 K Spore Coat
NHPPAGDG_00999 2.1e-213 spsE 2.5.1.56 M acid synthase
NHPPAGDG_01000 1.3e-128 spsF M Spore Coat
NHPPAGDG_01001 2.3e-187 spsG M Spore Coat
NHPPAGDG_01002 4.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHPPAGDG_01003 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHPPAGDG_01004 1.7e-83 spsL 5.1.3.13 M Spore Coat
NHPPAGDG_01005 1.2e-77
NHPPAGDG_01006 6.9e-206 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NHPPAGDG_01007 2.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NHPPAGDG_01008 0.0 rocB E arginine degradation protein
NHPPAGDG_01009 5.7e-261 lysP E amino acid
NHPPAGDG_01010 9.6e-204 ywfA EGP Major facilitator Superfamily
NHPPAGDG_01011 2.1e-111 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NHPPAGDG_01012 3e-76 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NHPPAGDG_01013 5.6e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPPAGDG_01014 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NHPPAGDG_01015 1.9e-209 bacE EGP Major facilitator Superfamily
NHPPAGDG_01016 5.8e-230 ywfG 2.6.1.83 E Aminotransferase class I and II
NHPPAGDG_01017 1.3e-137 IQ Enoyl-(Acyl carrier protein) reductase
NHPPAGDG_01018 1.1e-146 ywfI C May function as heme-dependent peroxidase
NHPPAGDG_01019 6.2e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NHPPAGDG_01020 7.8e-163 cysL K Transcriptional regulator
NHPPAGDG_01021 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NHPPAGDG_01022 1.7e-154 ywfM EG EamA-like transporter family
NHPPAGDG_01023 2.4e-107 rsfA_1
NHPPAGDG_01024 3.1e-36 ywzC S Belongs to the UPF0741 family
NHPPAGDG_01025 4.3e-255 ywfO S COG1078 HD superfamily phosphohydrolases
NHPPAGDG_01026 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
NHPPAGDG_01027 6.2e-79 yffB K Transcriptional regulator
NHPPAGDG_01028 1.6e-234 mmr U Major Facilitator Superfamily
NHPPAGDG_01030 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHPPAGDG_01031 3.3e-71 ywhA K Transcriptional regulator
NHPPAGDG_01032 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NHPPAGDG_01033 5.6e-118 ywhC S Peptidase family M50
NHPPAGDG_01034 9.9e-94 ywhD S YwhD family
NHPPAGDG_01035 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NHPPAGDG_01036 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NHPPAGDG_01037 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NHPPAGDG_01039 7.5e-86 S aspartate phosphatase
NHPPAGDG_01040 3e-190 ywhK CO amine dehydrogenase activity
NHPPAGDG_01041 4.3e-245 ywhL CO amine dehydrogenase activity
NHPPAGDG_01043 1e-245 L Peptidase, M16
NHPPAGDG_01044 2.6e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
NHPPAGDG_01045 1.6e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NHPPAGDG_01046 3.7e-131 cbiO V ABC transporter
NHPPAGDG_01048 1.4e-269 C Fe-S oxidoreductases
NHPPAGDG_01049 1e-07 S Bacteriocin subtilosin A
NHPPAGDG_01050 4.7e-73 ywiB S protein conserved in bacteria
NHPPAGDG_01051 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NHPPAGDG_01052 2.3e-213 narK P COG2223 Nitrate nitrite transporter
NHPPAGDG_01053 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
NHPPAGDG_01054 1.7e-139 ywiC S YwiC-like protein
NHPPAGDG_01055 7e-86 arfM T cyclic nucleotide binding
NHPPAGDG_01056 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHPPAGDG_01057 4.3e-296 narH 1.7.5.1 C Nitrate reductase, beta
NHPPAGDG_01058 1.1e-93 narJ 1.7.5.1 C nitrate reductase
NHPPAGDG_01059 2.6e-123 narI 1.7.5.1 C nitrate reductase, gamma
NHPPAGDG_01060 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHPPAGDG_01061 3.9e-229 ywjA V ABC transporter
NHPPAGDG_01062 1.4e-57 ywjA V ABC transporter
NHPPAGDG_01063 2.6e-94 ywjB H RibD C-terminal domain
NHPPAGDG_01064 3.5e-42 ywjC
NHPPAGDG_01065 8e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NHPPAGDG_01066 1.1e-212 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NHPPAGDG_01067 0.0 fadF C COG0247 Fe-S oxidoreductase
NHPPAGDG_01068 2.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NHPPAGDG_01069 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHPPAGDG_01070 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHPPAGDG_01071 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NHPPAGDG_01072 1e-108 yttP K Transcriptional regulator
NHPPAGDG_01073 1e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NHPPAGDG_01074 5.4e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHPPAGDG_01075 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NHPPAGDG_01076 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
NHPPAGDG_01077 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHPPAGDG_01078 2.2e-28 sspB S spore protein
NHPPAGDG_01079 1e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NHPPAGDG_01080 0.0 ytcJ S amidohydrolase
NHPPAGDG_01081 5.9e-146 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHPPAGDG_01082 1.1e-178 sppA OU signal peptide peptidase SppA
NHPPAGDG_01083 1.5e-86 yteJ S RDD family
NHPPAGDG_01084 9.6e-108 ytfI S Protein of unknown function (DUF2953)
NHPPAGDG_01085 1.5e-66 ytfJ S Sporulation protein YtfJ
NHPPAGDG_01086 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NHPPAGDG_01087 9.5e-162 ytxK 2.1.1.72 L DNA methylase
NHPPAGDG_01088 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHPPAGDG_01089 2.2e-85 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NHPPAGDG_01090 5.1e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHPPAGDG_01091 5.8e-266 argH 4.3.2.1 E argininosuccinate lyase
NHPPAGDG_01093 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPPAGDG_01094 3.9e-130 ytkL S Belongs to the UPF0173 family
NHPPAGDG_01095 2.9e-173 ytlI K LysR substrate binding domain
NHPPAGDG_01096 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
NHPPAGDG_01097 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
NHPPAGDG_01098 1.3e-145 tcyK M Bacterial periplasmic substrate-binding proteins
NHPPAGDG_01099 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
NHPPAGDG_01100 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
NHPPAGDG_01101 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NHPPAGDG_01102 4.2e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPPAGDG_01103 7.9e-45 ytnI O COG0695 Glutaredoxin and related proteins
NHPPAGDG_01104 1.8e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPPAGDG_01105 3.4e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NHPPAGDG_01106 7.3e-188 ytnL 3.5.1.47 E hydrolase activity
NHPPAGDG_01107 6e-155 ytnM S membrane transporter protein
NHPPAGDG_01108 8e-241 ytoI K transcriptional regulator containing CBS domains
NHPPAGDG_01109 2.4e-47 ytpI S YtpI-like protein
NHPPAGDG_01110 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NHPPAGDG_01111 9.2e-29
NHPPAGDG_01112 8.2e-69 ytrI
NHPPAGDG_01113 3.2e-56 ytrH S Sporulation protein YtrH
NHPPAGDG_01114 0.0 dnaE 2.7.7.7 L DNA polymerase
NHPPAGDG_01115 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NHPPAGDG_01116 3.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHPPAGDG_01117 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NHPPAGDG_01118 2.8e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHPPAGDG_01119 4.9e-311 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NHPPAGDG_01120 3.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NHPPAGDG_01121 2.6e-192 ytvI S sporulation integral membrane protein YtvI
NHPPAGDG_01122 4.7e-71 yeaL S membrane
NHPPAGDG_01123 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NHPPAGDG_01124 4.1e-242 icd 1.1.1.42 C isocitrate
NHPPAGDG_01125 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NHPPAGDG_01126 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_01127 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NHPPAGDG_01128 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHPPAGDG_01129 3.3e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHPPAGDG_01130 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NHPPAGDG_01131 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHPPAGDG_01132 1.7e-159 ytbE S reductase
NHPPAGDG_01133 3.3e-201 ytbD EGP Major facilitator Superfamily
NHPPAGDG_01134 6.5e-15 ytcD K Transcriptional regulator
NHPPAGDG_01135 2.8e-41 ytcD K Transcriptional regulator
NHPPAGDG_01136 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHPPAGDG_01137 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NHPPAGDG_01138 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHPPAGDG_01139 8.5e-265 dnaB L Membrane attachment protein
NHPPAGDG_01140 3.3e-172 dnaI L Primosomal protein DnaI
NHPPAGDG_01141 1.1e-107 ytxB S SNARE associated Golgi protein
NHPPAGDG_01142 1.6e-157 ytxC S YtxC-like family
NHPPAGDG_01144 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHPPAGDG_01145 7.3e-149 ysaA S HAD-hyrolase-like
NHPPAGDG_01146 0.0 lytS 2.7.13.3 T Histidine kinase
NHPPAGDG_01147 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
NHPPAGDG_01148 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NHPPAGDG_01149 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NHPPAGDG_01151 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHPPAGDG_01152 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NHPPAGDG_01153 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHPPAGDG_01154 7.5e-45 ysdA S Membrane
NHPPAGDG_01155 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NHPPAGDG_01156 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
NHPPAGDG_01157 4e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NHPPAGDG_01158 1e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NHPPAGDG_01159 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NHPPAGDG_01160 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NHPPAGDG_01161 2.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NHPPAGDG_01162 3.1e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NHPPAGDG_01163 6.4e-251 araN G carbohydrate transport
NHPPAGDG_01164 4.2e-167 araP G carbohydrate transport
NHPPAGDG_01165 2.9e-143 araQ G transport system permease
NHPPAGDG_01166 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NHPPAGDG_01167 0.0 cstA T Carbon starvation protein
NHPPAGDG_01168 3.6e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
NHPPAGDG_01169 7.1e-253 glcF C Glycolate oxidase
NHPPAGDG_01170 2.2e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
NHPPAGDG_01171 2.4e-206 ysfB KT regulator
NHPPAGDG_01172 2.6e-32 sspI S Belongs to the SspI family
NHPPAGDG_01173 1.7e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHPPAGDG_01174 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHPPAGDG_01175 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHPPAGDG_01176 2.1e-166 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHPPAGDG_01177 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NHPPAGDG_01178 3.9e-85 cvpA S membrane protein, required for colicin V production
NHPPAGDG_01179 0.0 polX L COG1796 DNA polymerase IV (family X)
NHPPAGDG_01180 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHPPAGDG_01181 7.3e-68 yshE S membrane
NHPPAGDG_01182 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NHPPAGDG_01183 1.4e-99 fadR K Transcriptional regulator
NHPPAGDG_01184 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NHPPAGDG_01185 3.8e-134 etfB C Electron transfer flavoprotein
NHPPAGDG_01186 1.1e-175 etfA C Electron transfer flavoprotein
NHPPAGDG_01188 7.8e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NHPPAGDG_01189 2e-52 trxA O Belongs to the thioredoxin family
NHPPAGDG_01190 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHPPAGDG_01191 5.4e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NHPPAGDG_01192 1.2e-79 yslB S Protein of unknown function (DUF2507)
NHPPAGDG_01193 2.4e-107 sdhC C succinate dehydrogenase
NHPPAGDG_01194 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NHPPAGDG_01195 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NHPPAGDG_01196 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NHPPAGDG_01197 1.2e-17 gerE K Transcriptional regulator
NHPPAGDG_01199 2.3e-66 M NLP P60 protein
NHPPAGDG_01201 3.6e-63 K Protein of unknown function (DUF4065)
NHPPAGDG_01202 5.9e-47 S YolD-like protein
NHPPAGDG_01203 5.2e-167 L Recombinase
NHPPAGDG_01204 3.4e-48 yqaB E IrrE N-terminal-like domain
NHPPAGDG_01205 2.9e-20
NHPPAGDG_01206 3.7e-24 K sequence-specific DNA binding
NHPPAGDG_01207 8.1e-14 K Helix-turn-helix XRE-family like proteins
NHPPAGDG_01209 5e-24
NHPPAGDG_01211 4.1e-45 S DNA binding
NHPPAGDG_01212 3e-83
NHPPAGDG_01217 2.9e-152 yqaJ L YqaJ-like viral recombinase domain
NHPPAGDG_01218 1.8e-116 recT L RecT family
NHPPAGDG_01219 2e-36 3.1.3.16 L DnaD domain protein
NHPPAGDG_01220 1.5e-120 xkdC L IstB-like ATP binding protein
NHPPAGDG_01222 1.3e-07
NHPPAGDG_01223 4e-54 S Protein of unknown function (DUF1064)
NHPPAGDG_01225 4.7e-19 S HNH endonuclease
NHPPAGDG_01226 7.1e-27 yqaO S Phage-like element PBSX protein XtrA
NHPPAGDG_01229 7.9e-96 ydiP 2.1.1.37 H C-5 cytosine-specific DNA methylase
NHPPAGDG_01232 5.8e-70 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NHPPAGDG_01234 2.1e-13 K Transcriptional regulator
NHPPAGDG_01237 6.2e-22 S Inner spore coat protein D
NHPPAGDG_01240 1.8e-80 yqaS L DNA packaging
NHPPAGDG_01241 1.4e-162 S Terminase RNAseH like domain
NHPPAGDG_01242 1e-161 S Phage portal protein, SPP1 Gp6-like
NHPPAGDG_01243 3.2e-58 S Domain of unknown function (DUF4355)
NHPPAGDG_01244 1.5e-123 S P22 coat protein - gene protein 5
NHPPAGDG_01246 7.6e-30 S Phage Mu protein F like protein
NHPPAGDG_01247 1.5e-18 S Phage gp6-like head-tail connector protein
NHPPAGDG_01248 2.6e-46
NHPPAGDG_01249 1.8e-23
NHPPAGDG_01250 2.4e-30
NHPPAGDG_01251 7.2e-104 Z012_02110 S Protein of unknown function (DUF3383)
NHPPAGDG_01252 3e-34
NHPPAGDG_01253 3.6e-16
NHPPAGDG_01254 1.4e-127 N phage tail tape measure protein
NHPPAGDG_01255 1.4e-40 3.5.1.28 M LysM domain
NHPPAGDG_01256 6.3e-31
NHPPAGDG_01257 5.5e-90
NHPPAGDG_01258 3e-22
NHPPAGDG_01259 1.8e-22 S Protein of unknown function (DUF2634)
NHPPAGDG_01260 2e-105 Z012_12235 S homolog of phage Mu protein gp47
NHPPAGDG_01261 6.6e-60
NHPPAGDG_01262 1.2e-44
NHPPAGDG_01264 1e-14 xkdX
NHPPAGDG_01265 1.5e-27 xhlA S Haemolysin XhlA
NHPPAGDG_01266 7.9e-31 xhlB S SPP1 phage holin
NHPPAGDG_01267 4.9e-103 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NHPPAGDG_01268 6.1e-52 V HNH endonuclease
NHPPAGDG_01269 5.2e-93 yokH G SMI1 / KNR4 family
NHPPAGDG_01270 4.1e-24 S SMI1-KNR4 cell-wall
NHPPAGDG_01271 5.1e-161 yobL S Bacterial EndoU nuclease
NHPPAGDG_01272 1.3e-182 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHPPAGDG_01273 1.4e-204 rpsA 1.17.7.4 J Ribosomal protein S1
NHPPAGDG_01274 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NHPPAGDG_01275 1.8e-23 S Family of unknown function (DUF5359)
NHPPAGDG_01276 1.5e-107 ypfA M Flagellar protein YcgR
NHPPAGDG_01277 2.1e-252 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NHPPAGDG_01278 7e-151 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NHPPAGDG_01279 2.5e-118 prsW S Involved in the degradation of specific anti-sigma factors
NHPPAGDG_01280 1.5e-175 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NHPPAGDG_01281 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NHPPAGDG_01282 9.1e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NHPPAGDG_01283 3.4e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
NHPPAGDG_01284 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NHPPAGDG_01285 5.5e-74 ypbE M Lysin motif
NHPPAGDG_01286 6.9e-99 ypbD S metal-dependent membrane protease
NHPPAGDG_01287 4.6e-285 recQ 3.6.4.12 L DNA helicase
NHPPAGDG_01288 6.5e-201 ypbB 5.1.3.1 S protein conserved in bacteria
NHPPAGDG_01289 6.1e-41 fer C Ferredoxin
NHPPAGDG_01290 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHPPAGDG_01291 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPPAGDG_01292 5e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NHPPAGDG_01293 6.6e-188 rsiX
NHPPAGDG_01294 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_01295 0.0 resE 2.7.13.3 T Histidine kinase
NHPPAGDG_01296 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_01297 5.3e-212 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NHPPAGDG_01298 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NHPPAGDG_01299 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NHPPAGDG_01300 2e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHPPAGDG_01301 1.9e-87 spmB S Spore maturation protein
NHPPAGDG_01302 5.9e-103 spmA S Spore maturation protein
NHPPAGDG_01303 4e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NHPPAGDG_01304 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NHPPAGDG_01305 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHPPAGDG_01306 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHPPAGDG_01307 1e-90 ypuF S Domain of unknown function (DUF309)
NHPPAGDG_01308 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPPAGDG_01309 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHPPAGDG_01310 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NHPPAGDG_01311 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
NHPPAGDG_01312 8.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHPPAGDG_01313 7.8e-55 ypuD
NHPPAGDG_01314 3.6e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NHPPAGDG_01316 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NHPPAGDG_01319 4.7e-09 eaeH M Domain of Unknown Function (DUF1259)
NHPPAGDG_01321 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHPPAGDG_01322 3.6e-149 ypuA S Secreted protein
NHPPAGDG_01323 1.5e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHPPAGDG_01324 3.7e-271 spoVAF EG Stage V sporulation protein AF
NHPPAGDG_01325 4e-110 spoVAEA S stage V sporulation protein
NHPPAGDG_01326 2.9e-57 spoVAEB S stage V sporulation protein
NHPPAGDG_01327 9e-192 spoVAD I Stage V sporulation protein AD
NHPPAGDG_01328 4.3e-77 spoVAC S stage V sporulation protein AC
NHPPAGDG_01329 1.7e-67 spoVAB S Stage V sporulation protein AB
NHPPAGDG_01330 2.8e-111 spoVAA S Stage V sporulation protein AA
NHPPAGDG_01331 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPPAGDG_01332 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NHPPAGDG_01333 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NHPPAGDG_01334 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NHPPAGDG_01335 3.8e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NHPPAGDG_01336 6.7e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHPPAGDG_01337 2.6e-166 xerD L recombinase XerD
NHPPAGDG_01338 1.4e-36 S Protein of unknown function (DUF4227)
NHPPAGDG_01339 2.4e-80 fur P Belongs to the Fur family
NHPPAGDG_01340 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NHPPAGDG_01341 2.2e-31 yqkK
NHPPAGDG_01342 5.5e-242 mleA 1.1.1.38 C malic enzyme
NHPPAGDG_01343 9.1e-235 mleN C Na H antiporter
NHPPAGDG_01344 1.9e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NHPPAGDG_01345 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase
NHPPAGDG_01346 1.3e-57 ansR K Transcriptional regulator
NHPPAGDG_01347 3.1e-220 yqxK 3.6.4.12 L DNA helicase
NHPPAGDG_01348 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NHPPAGDG_01350 7e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NHPPAGDG_01351 9.1e-12 yqkE S Protein of unknown function (DUF3886)
NHPPAGDG_01352 1.2e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NHPPAGDG_01353 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NHPPAGDG_01354 2.8e-54 yqkB S Belongs to the HesB IscA family
NHPPAGDG_01355 9.8e-194 yqkA K GrpB protein
NHPPAGDG_01356 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NHPPAGDG_01357 8.1e-87 yqjY K acetyltransferase
NHPPAGDG_01358 1.7e-49 S YolD-like protein
NHPPAGDG_01359 2e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHPPAGDG_01361 5.8e-225 yqjV G Major Facilitator Superfamily
NHPPAGDG_01363 3e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPPAGDG_01364 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
NHPPAGDG_01365 4.6e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NHPPAGDG_01366 6.6e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPPAGDG_01367 1.6e-177 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NHPPAGDG_01368 1.3e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHPPAGDG_01369 0.0 rocB E arginine degradation protein
NHPPAGDG_01370 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NHPPAGDG_01371 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHPPAGDG_01373 1.4e-34 ydjO S Cold-inducible protein YdjO
NHPPAGDG_01374 5.8e-157 ydjP I Alpha/beta hydrolase family
NHPPAGDG_01375 8e-177 yeaA S Protein of unknown function (DUF4003)
NHPPAGDG_01376 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NHPPAGDG_01377 7.5e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NHPPAGDG_01378 3.5e-152 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHPPAGDG_01379 3e-176 yeaC S COG0714 MoxR-like ATPases
NHPPAGDG_01380 1.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NHPPAGDG_01381 0.0 yebA E COG1305 Transglutaminase-like enzymes
NHPPAGDG_01382 1.9e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NHPPAGDG_01383 4.5e-37 K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_01384 1.5e-43 K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_01385 9.8e-256 S Domain of unknown function (DUF4179)
NHPPAGDG_01386 3.3e-210 pbuG S permease
NHPPAGDG_01387 4.4e-117 yebC M Membrane
NHPPAGDG_01389 4e-93 yebE S UPF0316 protein
NHPPAGDG_01390 8e-28 yebG S NETI protein
NHPPAGDG_01391 1.4e-81 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHPPAGDG_01392 8.5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHPPAGDG_01393 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHPPAGDG_01394 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NHPPAGDG_01395 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHPPAGDG_01396 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHPPAGDG_01397 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHPPAGDG_01398 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHPPAGDG_01399 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NHPPAGDG_01400 4.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHPPAGDG_01401 1.7e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NHPPAGDG_01402 2e-233 purD 6.3.4.13 F Belongs to the GARS family
NHPPAGDG_01403 1e-72 K helix_turn_helix ASNC type
NHPPAGDG_01404 5.4e-226 yjeH E Amino acid permease
NHPPAGDG_01405 2.7e-27 S Protein of unknown function (DUF2892)
NHPPAGDG_01406 0.0 yerA 3.5.4.2 F adenine deaminase
NHPPAGDG_01407 1e-187 yerB S Protein of unknown function (DUF3048) C-terminal domain
NHPPAGDG_01408 4.8e-51 yerC S protein conserved in bacteria
NHPPAGDG_01409 1.9e-197 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NHPPAGDG_01410 4.9e-32 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NHPPAGDG_01412 8.4e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NHPPAGDG_01413 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NHPPAGDG_01414 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHPPAGDG_01415 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NHPPAGDG_01416 1.2e-196 yerI S homoserine kinase type II (protein kinase fold)
NHPPAGDG_01417 1.6e-123 sapB S MgtC SapB transporter
NHPPAGDG_01418 7.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPPAGDG_01419 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHPPAGDG_01420 1e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHPPAGDG_01421 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHPPAGDG_01422 3.1e-145 yerO K Transcriptional regulator
NHPPAGDG_01423 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NHPPAGDG_01424 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHPPAGDG_01425 1.9e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHPPAGDG_01427 3.7e-101 S response regulator aspartate phosphatase
NHPPAGDG_01429 2.6e-29 S Colicin immunity protein / pyocin immunity protein
NHPPAGDG_01431 2.7e-82 S Protein of unknown function, DUF600
NHPPAGDG_01432 0.0 L nucleic acid phosphodiester bond hydrolysis
NHPPAGDG_01433 5.9e-96 3.4.24.40 CO amine dehydrogenase activity
NHPPAGDG_01434 3.6e-58 3.4.24.40 CO amine dehydrogenase activity
NHPPAGDG_01435 7.4e-211 S Tetratricopeptide repeat
NHPPAGDG_01437 2.7e-126 yeeN K transcriptional regulatory protein
NHPPAGDG_01439 6.7e-99 dhaR3 K Transcriptional regulator
NHPPAGDG_01440 6.9e-45 cotJA S Spore coat associated protein JA (CotJA)
NHPPAGDG_01441 5.6e-45 cotJB S CotJB protein
NHPPAGDG_01442 2e-103 cotJC P Spore Coat
NHPPAGDG_01443 6e-102 yesJ K Acetyltransferase (GNAT) family
NHPPAGDG_01445 5e-100 yesL S Protein of unknown function, DUF624
NHPPAGDG_01446 0.0 yesM 2.7.13.3 T Histidine kinase
NHPPAGDG_01447 8.8e-201 yesN K helix_turn_helix, arabinose operon control protein
NHPPAGDG_01448 3.6e-246 yesO G Bacterial extracellular solute-binding protein
NHPPAGDG_01449 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
NHPPAGDG_01450 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
NHPPAGDG_01451 3.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NHPPAGDG_01452 0.0 yesS K Transcriptional regulator
NHPPAGDG_01453 1.1e-129 E GDSL-like Lipase/Acylhydrolase
NHPPAGDG_01454 2.8e-125 yesU S Domain of unknown function (DUF1961)
NHPPAGDG_01455 2.4e-110 yesV S Protein of unknown function, DUF624
NHPPAGDG_01456 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NHPPAGDG_01457 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NHPPAGDG_01458 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
NHPPAGDG_01459 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NHPPAGDG_01460 2.7e-100 yetA
NHPPAGDG_01461 8.2e-156 yetA
NHPPAGDG_01462 1.4e-289 lplA G Bacterial extracellular solute-binding protein
NHPPAGDG_01463 1.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NHPPAGDG_01464 1.4e-161 lplC G Binding-protein-dependent transport system inner membrane component
NHPPAGDG_01465 2.3e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NHPPAGDG_01466 1.7e-120 yetF S membrane
NHPPAGDG_01467 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NHPPAGDG_01468 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPPAGDG_01469 1.1e-33
NHPPAGDG_01470 2.7e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHPPAGDG_01471 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NHPPAGDG_01472 9.1e-105 yetJ S Belongs to the BI1 family
NHPPAGDG_01473 2.4e-30 yetM CH FAD binding domain
NHPPAGDG_01474 5.6e-134 M Membrane
NHPPAGDG_01475 1.6e-94 ywlG S Belongs to the UPF0340 family
NHPPAGDG_01476 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NHPPAGDG_01477 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHPPAGDG_01478 1.1e-90 mntP P Probably functions as a manganese efflux pump
NHPPAGDG_01479 2.2e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHPPAGDG_01480 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NHPPAGDG_01481 6.1e-112 spoIIR S stage II sporulation protein R
NHPPAGDG_01482 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
NHPPAGDG_01484 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHPPAGDG_01485 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHPPAGDG_01486 2.6e-53 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPPAGDG_01487 5.1e-88 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NHPPAGDG_01488 8.6e-160 ywkB S Membrane transport protein
NHPPAGDG_01489 0.0 sfcA 1.1.1.38 C malic enzyme
NHPPAGDG_01490 1.6e-103 tdk 2.7.1.21 F thymidine kinase
NHPPAGDG_01491 1.1e-32 rpmE J Binds the 23S rRNA
NHPPAGDG_01492 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NHPPAGDG_01493 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NHPPAGDG_01494 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHPPAGDG_01495 9.9e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NHPPAGDG_01496 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NHPPAGDG_01497 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NHPPAGDG_01498 1.3e-90 ywjG S Domain of unknown function (DUF2529)
NHPPAGDG_01499 2.9e-76 ctsR K Belongs to the CtsR family
NHPPAGDG_01500 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NHPPAGDG_01501 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NHPPAGDG_01502 0.0 clpC O Belongs to the ClpA ClpB family
NHPPAGDG_01503 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHPPAGDG_01504 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NHPPAGDG_01505 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NHPPAGDG_01506 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NHPPAGDG_01507 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NHPPAGDG_01508 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHPPAGDG_01509 9.5e-118 cysE 2.3.1.30 E Serine acetyltransferase
NHPPAGDG_01510 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHPPAGDG_01511 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHPPAGDG_01512 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHPPAGDG_01513 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NHPPAGDG_01514 4.4e-115 sigH K Belongs to the sigma-70 factor family
NHPPAGDG_01515 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NHPPAGDG_01516 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NHPPAGDG_01517 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHPPAGDG_01518 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHPPAGDG_01519 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHPPAGDG_01520 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHPPAGDG_01521 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NHPPAGDG_01522 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPPAGDG_01523 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPPAGDG_01524 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NHPPAGDG_01525 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHPPAGDG_01526 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHPPAGDG_01527 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHPPAGDG_01528 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHPPAGDG_01529 1.7e-184 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NHPPAGDG_01530 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NHPPAGDG_01531 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHPPAGDG_01532 3e-105 rplD J Forms part of the polypeptide exit tunnel
NHPPAGDG_01533 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHPPAGDG_01534 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHPPAGDG_01535 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHPPAGDG_01536 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHPPAGDG_01537 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHPPAGDG_01538 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHPPAGDG_01539 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NHPPAGDG_01540 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHPPAGDG_01541 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHPPAGDG_01542 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHPPAGDG_01543 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHPPAGDG_01544 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHPPAGDG_01545 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHPPAGDG_01546 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHPPAGDG_01547 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHPPAGDG_01548 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHPPAGDG_01549 1.9e-23 rpmD J Ribosomal protein L30
NHPPAGDG_01550 1.8e-72 rplO J binds to the 23S rRNA
NHPPAGDG_01551 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHPPAGDG_01552 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHPPAGDG_01553 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NHPPAGDG_01554 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHPPAGDG_01555 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NHPPAGDG_01556 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHPPAGDG_01557 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHPPAGDG_01558 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPPAGDG_01559 3.6e-58 rplQ J Ribosomal protein L17
NHPPAGDG_01560 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHPPAGDG_01561 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHPPAGDG_01562 2.6e-117 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHPPAGDG_01563 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHPPAGDG_01564 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHPPAGDG_01565 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NHPPAGDG_01566 1.2e-143 ybaJ Q Methyltransferase domain
NHPPAGDG_01567 3.5e-71 ybaK S Protein of unknown function (DUF2521)
NHPPAGDG_01568 2.8e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPPAGDG_01569 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NHPPAGDG_01570 1.2e-84 gerD
NHPPAGDG_01571 6.6e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NHPPAGDG_01572 3.5e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NHPPAGDG_01573 1.7e-111 yokF 3.1.31.1 L RNA catabolic process
NHPPAGDG_01574 6.8e-254 iolT EGP Major facilitator Superfamily
NHPPAGDG_01575 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHPPAGDG_01576 5.3e-83 yncE S Protein of unknown function (DUF2691)
NHPPAGDG_01577 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NHPPAGDG_01578 5.2e-15
NHPPAGDG_01581 5.6e-163 S Thymidylate synthase
NHPPAGDG_01582 5.4e-32
NHPPAGDG_01584 6.6e-131 S Domain of unknown function, YrpD
NHPPAGDG_01587 7.9e-25 tatA U protein secretion
NHPPAGDG_01588 1.8e-71
NHPPAGDG_01589 2.9e-78 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NHPPAGDG_01592 6.9e-284 gerAA EG Spore germination protein
NHPPAGDG_01593 1e-193 gerAB U Spore germination
NHPPAGDG_01594 5.5e-182 gerLC S Spore germination protein
NHPPAGDG_01595 2.9e-153 yndG S DoxX-like family
NHPPAGDG_01596 5.2e-113 yndH S Domain of unknown function (DUF4166)
NHPPAGDG_01597 1.6e-307 yndJ S YndJ-like protein
NHPPAGDG_01599 1.5e-135 yndL S Replication protein
NHPPAGDG_01600 2.9e-73 yndM S Protein of unknown function (DUF2512)
NHPPAGDG_01601 1.1e-77 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NHPPAGDG_01602 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHPPAGDG_01603 2.2e-48 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NHPPAGDG_01604 4.5e-112 yneB L resolvase
NHPPAGDG_01605 1.1e-31 ynzC S UPF0291 protein
NHPPAGDG_01606 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHPPAGDG_01607 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NHPPAGDG_01608 1.8e-28 yneF S UPF0154 protein
NHPPAGDG_01609 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NHPPAGDG_01610 7.1e-127 ccdA O cytochrome c biogenesis protein
NHPPAGDG_01611 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NHPPAGDG_01612 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NHPPAGDG_01613 3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NHPPAGDG_01614 0.0 oppA E ABC transporter substrate-binding protein
NHPPAGDG_01615 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPPAGDG_01616 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPPAGDG_01617 3.4e-197 oppD P Belongs to the ABC transporter superfamily
NHPPAGDG_01618 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NHPPAGDG_01619 2e-203 yjbB EGP Major Facilitator Superfamily
NHPPAGDG_01620 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPPAGDG_01621 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHPPAGDG_01622 6e-112 yjbE P Integral membrane protein TerC family
NHPPAGDG_01623 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NHPPAGDG_01624 4e-220 yjbF S Competence protein
NHPPAGDG_01625 0.0 pepF E oligoendopeptidase F
NHPPAGDG_01626 1.8e-20
NHPPAGDG_01628 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NHPPAGDG_01629 3.7e-72 yjbI S Bacterial-like globin
NHPPAGDG_01630 3.2e-98 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NHPPAGDG_01631 4.1e-101 yjbK S protein conserved in bacteria
NHPPAGDG_01632 7.1e-62 yjbL S Belongs to the UPF0738 family
NHPPAGDG_01633 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NHPPAGDG_01634 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHPPAGDG_01635 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHPPAGDG_01636 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NHPPAGDG_01637 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NHPPAGDG_01638 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHPPAGDG_01639 1.1e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NHPPAGDG_01640 2.6e-216 thiO 1.4.3.19 E Glycine oxidase
NHPPAGDG_01641 6.7e-30 thiS H thiamine diphosphate biosynthetic process
NHPPAGDG_01642 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NHPPAGDG_01643 1.9e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHPPAGDG_01644 1.3e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NHPPAGDG_01645 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NHPPAGDG_01646 1.4e-52 yjbX S Spore coat protein
NHPPAGDG_01647 5.2e-83 cotZ S Spore coat protein
NHPPAGDG_01648 3.4e-96 cotY S Spore coat protein Z
NHPPAGDG_01649 6.4e-77 cotX S Spore Coat Protein X and V domain
NHPPAGDG_01650 3e-32 cotW
NHPPAGDG_01651 2.3e-55 cotV S Spore Coat Protein X and V domain
NHPPAGDG_01652 4.3e-56 yjcA S Protein of unknown function (DUF1360)
NHPPAGDG_01655 2.9e-38 spoVIF S Stage VI sporulation protein F
NHPPAGDG_01656 0.0 yjcD 3.6.4.12 L DNA helicase
NHPPAGDG_01657 1.7e-38
NHPPAGDG_01658 4.3e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPPAGDG_01659 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NHPPAGDG_01660 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
NHPPAGDG_01661 8.6e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NHPPAGDG_01662 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NHPPAGDG_01663 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
NHPPAGDG_01664 3.9e-210 yjcL S Protein of unknown function (DUF819)
NHPPAGDG_01666 2.3e-18
NHPPAGDG_01667 8.7e-31
NHPPAGDG_01669 8.5e-60
NHPPAGDG_01670 2.8e-11
NHPPAGDG_01672 5.9e-11
NHPPAGDG_01673 1.6e-43
NHPPAGDG_01677 1.1e-81 S aspartate phosphatase
NHPPAGDG_01678 3.9e-18 S aspartate phosphatase
NHPPAGDG_01679 3.6e-281 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NHPPAGDG_01680 7.3e-80 S SMI1-KNR4 cell-wall
NHPPAGDG_01681 1e-07 S YpzI-like protein
NHPPAGDG_01682 3.3e-101 yphA
NHPPAGDG_01683 2.5e-161 seaA S YIEGIA protein
NHPPAGDG_01684 6e-28 ypzH
NHPPAGDG_01685 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NHPPAGDG_01686 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NHPPAGDG_01687 2e-18 yphE S Protein of unknown function (DUF2768)
NHPPAGDG_01688 3.3e-135 yphF
NHPPAGDG_01689 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NHPPAGDG_01690 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHPPAGDG_01691 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NHPPAGDG_01692 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NHPPAGDG_01693 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NHPPAGDG_01694 4.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NHPPAGDG_01695 7.6e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHPPAGDG_01696 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NHPPAGDG_01697 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NHPPAGDG_01698 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHPPAGDG_01699 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NHPPAGDG_01700 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NHPPAGDG_01701 1.1e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHPPAGDG_01702 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHPPAGDG_01703 2.1e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NHPPAGDG_01704 1.8e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NHPPAGDG_01705 7.6e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHPPAGDG_01706 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHPPAGDG_01707 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NHPPAGDG_01708 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NHPPAGDG_01709 1.1e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHPPAGDG_01710 5.9e-233 S COG0457 FOG TPR repeat
NHPPAGDG_01711 3.1e-98 ypiB S Belongs to the UPF0302 family
NHPPAGDG_01712 1.4e-75 ypiF S Protein of unknown function (DUF2487)
NHPPAGDG_01713 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NHPPAGDG_01714 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NHPPAGDG_01715 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NHPPAGDG_01716 1.1e-99 ypjA S membrane
NHPPAGDG_01717 7.4e-141 ypjB S sporulation protein
NHPPAGDG_01718 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NHPPAGDG_01719 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NHPPAGDG_01720 1.2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHPPAGDG_01721 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NHPPAGDG_01722 7.6e-129 bshB1 S proteins, LmbE homologs
NHPPAGDG_01723 5e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NHPPAGDG_01724 3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHPPAGDG_01725 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHPPAGDG_01726 3.1e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NHPPAGDG_01727 6.8e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NHPPAGDG_01728 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NHPPAGDG_01729 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NHPPAGDG_01730 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NHPPAGDG_01731 2.2e-79 ypmB S protein conserved in bacteria
NHPPAGDG_01732 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NHPPAGDG_01733 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NHPPAGDG_01734 5.7e-129 dnaD L DNA replication protein DnaD
NHPPAGDG_01735 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHPPAGDG_01736 8e-93 ypoC
NHPPAGDG_01737 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NHPPAGDG_01738 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHPPAGDG_01739 2.6e-188 yppC S Protein of unknown function (DUF2515)
NHPPAGDG_01742 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
NHPPAGDG_01744 1.2e-48 yppG S YppG-like protein
NHPPAGDG_01745 2.5e-71 hspX O Belongs to the small heat shock protein (HSP20) family
NHPPAGDG_01746 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NHPPAGDG_01747 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NHPPAGDG_01748 1.9e-236 yprB L RNase_H superfamily
NHPPAGDG_01749 5.3e-90 ypsA S Belongs to the UPF0398 family
NHPPAGDG_01750 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHPPAGDG_01751 9.2e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NHPPAGDG_01753 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NHPPAGDG_01754 1.3e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPPAGDG_01755 4.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NHPPAGDG_01756 3.3e-186 ptxS K transcriptional
NHPPAGDG_01757 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NHPPAGDG_01758 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NHPPAGDG_01759 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NHPPAGDG_01760 9.3e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NHPPAGDG_01761 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHPPAGDG_01762 2.9e-227 pbuX F xanthine
NHPPAGDG_01763 6.3e-207 bcsA Q Naringenin-chalcone synthase
NHPPAGDG_01764 6.7e-87 ypbQ S protein conserved in bacteria
NHPPAGDG_01766 0.0 ypbR S Dynamin family
NHPPAGDG_01767 2.9e-38 ypbS S Protein of unknown function (DUF2533)
NHPPAGDG_01768 2e-07
NHPPAGDG_01769 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NHPPAGDG_01771 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
NHPPAGDG_01772 2.8e-120 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NHPPAGDG_01773 1.7e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NHPPAGDG_01774 2.6e-27 ypeQ S Zinc-finger
NHPPAGDG_01775 8.1e-31 S Protein of unknown function (DUF2564)
NHPPAGDG_01776 3.8e-16 degR
NHPPAGDG_01777 1e-30 cspD K Cold-shock protein
NHPPAGDG_01778 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NHPPAGDG_01779 1.2e-174 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHPPAGDG_01780 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NHPPAGDG_01781 6.7e-58 ypgQ S phosphohydrolase
NHPPAGDG_01782 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
NHPPAGDG_01783 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NHPPAGDG_01784 1.7e-75 yphP S Belongs to the UPF0403 family
NHPPAGDG_01785 6.5e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NHPPAGDG_01786 5.5e-104 ypjP S YpjP-like protein
NHPPAGDG_01787 3.6e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NHPPAGDG_01788 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHPPAGDG_01789 4.8e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHPPAGDG_01790 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NHPPAGDG_01791 4.2e-110 hlyIII S protein, Hemolysin III
NHPPAGDG_01792 6.8e-184 pspF K Transcriptional regulator
NHPPAGDG_01793 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHPPAGDG_01794 3.1e-40 ypmP S Protein of unknown function (DUF2535)
NHPPAGDG_01795 1.3e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NHPPAGDG_01796 1.1e-136 ypmR E GDSL-like Lipase/Acylhydrolase
NHPPAGDG_01797 1.1e-98 ypmS S protein conserved in bacteria
NHPPAGDG_01798 1.2e-28 ypmT S Uncharacterized ympT
NHPPAGDG_01799 1.9e-221 mepA V MATE efflux family protein
NHPPAGDG_01800 1.6e-70 ypoP K transcriptional
NHPPAGDG_01801 3.9e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHPPAGDG_01802 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NHPPAGDG_01803 9.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
NHPPAGDG_01804 1.9e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NHPPAGDG_01805 7.7e-177 cgeB S Spore maturation protein
NHPPAGDG_01806 8.2e-64 cgeA
NHPPAGDG_01807 1e-37 cgeC
NHPPAGDG_01808 8e-254 cgeD M maturation of the outermost layer of the spore
NHPPAGDG_01809 9.2e-144 yiiD K acetyltransferase
NHPPAGDG_01811 3.2e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHPPAGDG_01812 2.4e-09 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHPPAGDG_01813 1.8e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NHPPAGDG_01814 9.3e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NHPPAGDG_01815 6.7e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NHPPAGDG_01816 2.6e-277 kamA 5.4.3.2 E lysine 2,3-aminomutase
NHPPAGDG_01817 2.9e-47 yokU S YokU-like protein, putative antitoxin
NHPPAGDG_01818 1.4e-36 yozE S Belongs to the UPF0346 family
NHPPAGDG_01819 6e-123 yodN
NHPPAGDG_01821 2.8e-24 yozD S YozD-like protein
NHPPAGDG_01822 4.3e-104 yodM 3.6.1.27 I Acid phosphatase homologues
NHPPAGDG_01823 7.9e-54 yodL S YodL-like
NHPPAGDG_01824 5.3e-09
NHPPAGDG_01825 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NHPPAGDG_01826 2.1e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NHPPAGDG_01827 2e-23 yodI
NHPPAGDG_01828 2.4e-127 yodH Q Methyltransferase
NHPPAGDG_01829 2.4e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NHPPAGDG_01830 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPPAGDG_01831 6.2e-28 S Protein of unknown function (DUF3311)
NHPPAGDG_01832 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
NHPPAGDG_01833 2.7e-111 mhqD S Carboxylesterase
NHPPAGDG_01834 1.2e-145 yknT
NHPPAGDG_01835 2.5e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NHPPAGDG_01836 2.2e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHPPAGDG_01837 5.2e-245 moeA 2.10.1.1 H molybdopterin
NHPPAGDG_01838 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NHPPAGDG_01839 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NHPPAGDG_01840 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NHPPAGDG_01841 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NHPPAGDG_01842 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NHPPAGDG_01843 1e-117 yknW S Yip1 domain
NHPPAGDG_01844 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHPPAGDG_01845 7.2e-124 macB V ABC transporter, ATP-binding protein
NHPPAGDG_01846 8.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NHPPAGDG_01847 3.1e-136 fruR K Transcriptional regulator
NHPPAGDG_01848 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NHPPAGDG_01849 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NHPPAGDG_01850 2.4e-104 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NHPPAGDG_01851 1.1e-38 ykoA
NHPPAGDG_01852 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHPPAGDG_01853 9e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHPPAGDG_01854 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NHPPAGDG_01855 1.1e-12 S Uncharacterized protein YkpC
NHPPAGDG_01856 7.7e-183 mreB D Rod-share determining protein MreBH
NHPPAGDG_01857 1.5e-43 abrB K of stationary sporulation gene expression
NHPPAGDG_01858 5.1e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NHPPAGDG_01859 2.5e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NHPPAGDG_01860 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NHPPAGDG_01861 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NHPPAGDG_01862 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHPPAGDG_01863 8.2e-31 ykzG S Belongs to the UPF0356 family
NHPPAGDG_01864 1e-145 ykrA S hydrolases of the HAD superfamily
NHPPAGDG_01865 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHPPAGDG_01867 2e-115 recN L Putative cell-wall binding lipoprotein
NHPPAGDG_01868 2.2e-191 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHPPAGDG_01869 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHPPAGDG_01870 2.4e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHPPAGDG_01871 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHPPAGDG_01872 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NHPPAGDG_01873 1.3e-276 speA 4.1.1.19 E Arginine
NHPPAGDG_01874 2e-42 yktA S Belongs to the UPF0223 family
NHPPAGDG_01875 2.1e-117 yktB S Belongs to the UPF0637 family
NHPPAGDG_01876 7.1e-26 ykzI
NHPPAGDG_01877 2.5e-149 suhB 3.1.3.25 G Inositol monophosphatase
NHPPAGDG_01878 6.9e-78 ykzC S Acetyltransferase (GNAT) family
NHPPAGDG_01879 1.9e-169 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NHPPAGDG_01880 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NHPPAGDG_01881 0.0 ylaA
NHPPAGDG_01882 6.6e-41 ylaB
NHPPAGDG_01883 1.1e-87 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_01884 2e-11 sigC S Putative zinc-finger
NHPPAGDG_01885 2.6e-37 ylaE
NHPPAGDG_01886 8.2e-22 S Family of unknown function (DUF5325)
NHPPAGDG_01887 0.0 typA T GTP-binding protein TypA
NHPPAGDG_01888 4.2e-47 ylaH S YlaH-like protein
NHPPAGDG_01889 2.5e-32 ylaI S protein conserved in bacteria
NHPPAGDG_01890 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHPPAGDG_01891 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NHPPAGDG_01892 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NHPPAGDG_01893 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NHPPAGDG_01894 8.7e-44 ylaN S Belongs to the UPF0358 family
NHPPAGDG_01895 3.6e-211 ftsW D Belongs to the SEDS family
NHPPAGDG_01896 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NHPPAGDG_01897 2.2e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NHPPAGDG_01898 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NHPPAGDG_01899 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NHPPAGDG_01900 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHPPAGDG_01901 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NHPPAGDG_01902 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NHPPAGDG_01903 1.6e-163 ctaG S cytochrome c oxidase
NHPPAGDG_01904 7.7e-61 ylbA S YugN-like family
NHPPAGDG_01905 2.6e-74 ylbB T COG0517 FOG CBS domain
NHPPAGDG_01906 4.3e-200 ylbC S protein with SCP PR1 domains
NHPPAGDG_01907 4.1e-63 ylbD S Putative coat protein
NHPPAGDG_01908 6.7e-37 ylbE S YlbE-like protein
NHPPAGDG_01909 1.8e-75 ylbF S Belongs to the UPF0342 family
NHPPAGDG_01910 7.5e-39 ylbG S UPF0298 protein
NHPPAGDG_01911 2.5e-95 rsmD 2.1.1.171 L Methyltransferase
NHPPAGDG_01912 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHPPAGDG_01913 4.7e-219 ylbJ S Sporulation integral membrane protein YlbJ
NHPPAGDG_01914 6.4e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
NHPPAGDG_01915 2.6e-186 ylbL T Belongs to the peptidase S16 family
NHPPAGDG_01916 2.8e-235 ylbM S Belongs to the UPF0348 family
NHPPAGDG_01918 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NHPPAGDG_01919 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NHPPAGDG_01920 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NHPPAGDG_01921 1.5e-88 ylbP K n-acetyltransferase
NHPPAGDG_01922 5.7e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHPPAGDG_01923 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NHPPAGDG_01924 2.9e-78 mraZ K Belongs to the MraZ family
NHPPAGDG_01925 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHPPAGDG_01926 3.7e-44 ftsL D Essential cell division protein
NHPPAGDG_01927 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NHPPAGDG_01928 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NHPPAGDG_01929 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHPPAGDG_01930 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHPPAGDG_01931 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHPPAGDG_01932 5.7e-186 spoVE D Belongs to the SEDS family
NHPPAGDG_01933 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHPPAGDG_01934 5.3e-167 murB 1.3.1.98 M cell wall formation
NHPPAGDG_01935 2.3e-126 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHPPAGDG_01936 2.8e-99 ylxW S protein conserved in bacteria
NHPPAGDG_01937 1.5e-101 ylxX S protein conserved in bacteria
NHPPAGDG_01938 6.2e-58 sbp S small basic protein
NHPPAGDG_01939 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHPPAGDG_01940 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHPPAGDG_01941 0.0 bpr O COG1404 Subtilisin-like serine proteases
NHPPAGDG_01942 1.6e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NHPPAGDG_01943 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPPAGDG_01944 6.8e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPPAGDG_01945 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NHPPAGDG_01946 5.2e-242 argE 3.5.1.16 E Acetylornithine deacetylase
NHPPAGDG_01947 2.4e-37 ylmC S sporulation protein
NHPPAGDG_01948 7e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NHPPAGDG_01949 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHPPAGDG_01950 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHPPAGDG_01951 1.3e-39 yggT S membrane
NHPPAGDG_01952 9.7e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NHPPAGDG_01953 2.6e-67 divIVA D Cell division initiation protein
NHPPAGDG_01954 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHPPAGDG_01955 1.3e-63 dksA T COG1734 DnaK suppressor protein
NHPPAGDG_01956 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHPPAGDG_01957 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHPPAGDG_01958 3.6e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHPPAGDG_01959 2.6e-231 pyrP F Xanthine uracil
NHPPAGDG_01960 2.9e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NHPPAGDG_01961 9.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHPPAGDG_01962 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NHPPAGDG_01963 0.0 carB 6.3.5.5 F Belongs to the CarB family
NHPPAGDG_01964 4.1e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NHPPAGDG_01965 5.4e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHPPAGDG_01966 3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHPPAGDG_01967 1.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHPPAGDG_01969 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NHPPAGDG_01970 4.1e-179 cysP P phosphate transporter
NHPPAGDG_01971 7.2e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NHPPAGDG_01972 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NHPPAGDG_01973 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NHPPAGDG_01974 1.6e-143 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NHPPAGDG_01975 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NHPPAGDG_01976 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NHPPAGDG_01977 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NHPPAGDG_01978 3.1e-156 yloC S stress-induced protein
NHPPAGDG_01979 1.5e-40 ylzA S Belongs to the UPF0296 family
NHPPAGDG_01980 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NHPPAGDG_01981 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHPPAGDG_01982 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHPPAGDG_01983 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHPPAGDG_01984 1.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHPPAGDG_01985 5.2e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHPPAGDG_01986 2.3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHPPAGDG_01987 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NHPPAGDG_01988 1.6e-140 stp 3.1.3.16 T phosphatase
NHPPAGDG_01989 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NHPPAGDG_01990 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHPPAGDG_01991 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NHPPAGDG_01992 2e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
NHPPAGDG_01993 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NHPPAGDG_01994 5.5e-59 asp S protein conserved in bacteria
NHPPAGDG_01995 1.6e-299 yloV S kinase related to dihydroxyacetone kinase
NHPPAGDG_01996 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NHPPAGDG_01997 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NHPPAGDG_01998 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHPPAGDG_01999 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NHPPAGDG_02000 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHPPAGDG_02001 1.7e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NHPPAGDG_02002 2.3e-128 IQ reductase
NHPPAGDG_02003 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHPPAGDG_02004 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHPPAGDG_02005 0.0 smc D Required for chromosome condensation and partitioning
NHPPAGDG_02006 2.6e-175 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHPPAGDG_02007 3.2e-125 S Phosphotransferase enzyme family
NHPPAGDG_02008 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHPPAGDG_02009 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHPPAGDG_02010 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NHPPAGDG_02011 4.5e-36 ylqC S Belongs to the UPF0109 family
NHPPAGDG_02012 1.4e-60 ylqD S YlqD protein
NHPPAGDG_02013 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHPPAGDG_02014 3.5e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NHPPAGDG_02015 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHPPAGDG_02016 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHPPAGDG_02017 2.9e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHPPAGDG_02018 6.1e-289 ylqG
NHPPAGDG_02019 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NHPPAGDG_02020 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NHPPAGDG_02021 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NHPPAGDG_02022 8e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NHPPAGDG_02023 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHPPAGDG_02024 3.7e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHPPAGDG_02025 2.5e-169 xerC L tyrosine recombinase XerC
NHPPAGDG_02026 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NHPPAGDG_02027 2.2e-249 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NHPPAGDG_02028 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NHPPAGDG_02029 3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NHPPAGDG_02030 7.6e-74 flgC N Belongs to the flagella basal body rod proteins family
NHPPAGDG_02031 1.9e-31 fliE N Flagellar hook-basal body
NHPPAGDG_02032 9.1e-255 fliF N The M ring may be actively involved in energy transduction
NHPPAGDG_02033 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NHPPAGDG_02034 9.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NHPPAGDG_02035 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NHPPAGDG_02036 4.2e-69 fliJ N Flagellar biosynthesis chaperone
NHPPAGDG_02037 3.8e-36 ylxF S MgtE intracellular N domain
NHPPAGDG_02038 2.3e-220 fliK N Flagellar hook-length control protein
NHPPAGDG_02039 8.7e-72 flgD N Flagellar basal body rod modification protein
NHPPAGDG_02040 1.3e-137 flgG N Flagellar basal body rod
NHPPAGDG_02041 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NHPPAGDG_02042 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NHPPAGDG_02043 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NHPPAGDG_02044 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NHPPAGDG_02045 6e-96 fliZ N Flagellar biosynthesis protein, FliO
NHPPAGDG_02046 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NHPPAGDG_02047 6.4e-36 fliQ N Role in flagellar biosynthesis
NHPPAGDG_02048 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NHPPAGDG_02049 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NHPPAGDG_02050 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NHPPAGDG_02051 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
NHPPAGDG_02052 1.6e-155 flhG D Belongs to the ParA family
NHPPAGDG_02053 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NHPPAGDG_02054 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NHPPAGDG_02055 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NHPPAGDG_02056 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NHPPAGDG_02057 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NHPPAGDG_02058 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPPAGDG_02059 3.1e-76 ylxL
NHPPAGDG_02060 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NHPPAGDG_02061 8.2e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHPPAGDG_02062 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NHPPAGDG_02063 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHPPAGDG_02064 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHPPAGDG_02065 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NHPPAGDG_02066 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NHPPAGDG_02067 7.7e-233 rasP M zinc metalloprotease
NHPPAGDG_02068 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHPPAGDG_02069 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHPPAGDG_02070 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NHPPAGDG_02071 1.1e-203 nusA K Participates in both transcription termination and antitermination
NHPPAGDG_02072 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NHPPAGDG_02073 3.1e-47 ylxQ J ribosomal protein
NHPPAGDG_02074 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHPPAGDG_02075 5e-44 ylxP S protein conserved in bacteria
NHPPAGDG_02076 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHPPAGDG_02077 7.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHPPAGDG_02078 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NHPPAGDG_02079 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHPPAGDG_02080 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NHPPAGDG_02081 2.2e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NHPPAGDG_02082 4.4e-233 pepR S Belongs to the peptidase M16 family
NHPPAGDG_02083 2.6e-42 ymxH S YlmC YmxH family
NHPPAGDG_02084 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NHPPAGDG_02085 1.4e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NHPPAGDG_02086 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHPPAGDG_02087 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NHPPAGDG_02088 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHPPAGDG_02089 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHPPAGDG_02090 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NHPPAGDG_02091 4.4e-32 S YlzJ-like protein
NHPPAGDG_02092 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NHPPAGDG_02093 1.4e-133 ymfC K Transcriptional regulator
NHPPAGDG_02094 3.8e-205 ymfD EGP Major facilitator Superfamily
NHPPAGDG_02095 3.9e-232 ymfF S Peptidase M16
NHPPAGDG_02096 1.4e-242 ymfH S zinc protease
NHPPAGDG_02097 5e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NHPPAGDG_02098 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NHPPAGDG_02099 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NHPPAGDG_02100 2.1e-115 ymfM S protein conserved in bacteria
NHPPAGDG_02101 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHPPAGDG_02102 8.1e-235 cinA 3.5.1.42 S Belongs to the CinA family
NHPPAGDG_02103 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHPPAGDG_02104 4.4e-214 pbpX V Beta-lactamase
NHPPAGDG_02105 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NHPPAGDG_02106 1.9e-152 ymdB S protein conserved in bacteria
NHPPAGDG_02107 1.2e-36 spoVS S Stage V sporulation protein S
NHPPAGDG_02108 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NHPPAGDG_02109 2.5e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NHPPAGDG_02110 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NHPPAGDG_02111 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NHPPAGDG_02112 2.2e-88 cotE S Spore coat protein
NHPPAGDG_02113 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHPPAGDG_02114 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHPPAGDG_02115 2.2e-68 S Regulatory protein YrvL
NHPPAGDG_02116 1.1e-95 ymcC S Membrane
NHPPAGDG_02117 1.2e-103 pksA K Transcriptional regulator
NHPPAGDG_02118 4.4e-61 ymzB
NHPPAGDG_02119 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
NHPPAGDG_02120 1.2e-249 aprX O Belongs to the peptidase S8 family
NHPPAGDG_02121 1.9e-07 K Transcriptional regulator
NHPPAGDG_02122 2.1e-126 ymaC S Replication protein
NHPPAGDG_02123 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
NHPPAGDG_02124 6.2e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NHPPAGDG_02125 4.9e-51 ebrA P Small Multidrug Resistance protein
NHPPAGDG_02127 2.1e-46 ymaF S YmaF family
NHPPAGDG_02128 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHPPAGDG_02129 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NHPPAGDG_02130 8.2e-23
NHPPAGDG_02131 4.5e-22 ymzA
NHPPAGDG_02132 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NHPPAGDG_02133 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPPAGDG_02134 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPPAGDG_02135 2e-109 ymaB
NHPPAGDG_02136 2.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPPAGDG_02137 2.4e-97 spoVK O stage V sporulation protein K
NHPPAGDG_02139 2.4e-53 S SMI1 / KNR4 family
NHPPAGDG_02140 3.9e-106 yokF 3.1.31.1 L RNA catabolic process
NHPPAGDG_02141 3.9e-13
NHPPAGDG_02142 1.3e-102 yokH G SMI1 / KNR4 family
NHPPAGDG_02143 9.2e-230 L nucleic acid phosphodiester bond hydrolysis
NHPPAGDG_02144 1e-60 S Protein of unknown function, DUF600
NHPPAGDG_02145 2.2e-54 yokK S SMI1 / KNR4 family
NHPPAGDG_02148 1.3e-40
NHPPAGDG_02149 4.9e-54 S YolD-like protein
NHPPAGDG_02150 1.3e-215 S impB/mucB/samB family C-terminal domain
NHPPAGDG_02151 3.5e-12 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHPPAGDG_02154 0.0 V Peptidase C39 family
NHPPAGDG_02155 1.2e-70 CO cell redox homeostasis
NHPPAGDG_02156 7.7e-241 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPPAGDG_02157 3.4e-74 O protein disulfide oxidoreductase activity
NHPPAGDG_02158 5.5e-40 S SPP1 phage holin
NHPPAGDG_02159 4.4e-32 bhlA S BhlA holin family
NHPPAGDG_02160 2e-80 S N-acetylmuramoyl-L-alanine amidase activity
NHPPAGDG_02161 0.0 G Exopolysaccharide biosynthesis protein
NHPPAGDG_02162 1.1e-134
NHPPAGDG_02163 0.0 S Pfam Transposase IS66
NHPPAGDG_02164 1.8e-144 S Phage tail protein
NHPPAGDG_02165 0.0 S peptidoglycan catabolic process
NHPPAGDG_02166 5.4e-46
NHPPAGDG_02169 1.1e-13 S Protein of unknown function (DUF3990)
NHPPAGDG_02170 3.7e-190 xerH A Belongs to the 'phage' integrase family
NHPPAGDG_02171 8.7e-56
NHPPAGDG_02172 1.2e-56
NHPPAGDG_02173 1.5e-10 xkdX
NHPPAGDG_02174 8.1e-07
NHPPAGDG_02175 4.9e-168
NHPPAGDG_02176 6.6e-57
NHPPAGDG_02179 4.2e-59
NHPPAGDG_02180 1.8e-72
NHPPAGDG_02181 4.4e-78
NHPPAGDG_02182 1.6e-120
NHPPAGDG_02184 3.2e-68
NHPPAGDG_02185 1.1e-80
NHPPAGDG_02186 1.3e-185
NHPPAGDG_02187 7.8e-94
NHPPAGDG_02188 8.1e-255
NHPPAGDG_02189 9.1e-281
NHPPAGDG_02190 0.0 gp17a S Terminase-like family
NHPPAGDG_02191 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NHPPAGDG_02192 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NHPPAGDG_02193 2.3e-212 xylR GK ROK family
NHPPAGDG_02194 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NHPPAGDG_02195 6.2e-32 xynT G MFS/sugar transport protein
NHPPAGDG_02196 3.1e-212 xynT G MFS/sugar transport protein
NHPPAGDG_02197 4.2e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NHPPAGDG_02198 6.5e-71 S CAAX protease self-immunity
NHPPAGDG_02199 2.5e-141 spo0M S COG4326 Sporulation control protein
NHPPAGDG_02200 1.2e-26
NHPPAGDG_02201 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NHPPAGDG_02202 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NHPPAGDG_02203 7.6e-263 ygaK C Berberine and berberine like
NHPPAGDG_02205 2.3e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NHPPAGDG_02206 6.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NHPPAGDG_02207 1.6e-169 ssuA M Sulfonate ABC transporter
NHPPAGDG_02208 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NHPPAGDG_02209 2.6e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NHPPAGDG_02211 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHPPAGDG_02212 1.7e-76 ygaO
NHPPAGDG_02213 4.4e-29 K Transcriptional regulator
NHPPAGDG_02215 3.9e-113 yhzB S B3/4 domain
NHPPAGDG_02216 5.1e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHPPAGDG_02217 3.5e-174 yhbB S Putative amidase domain
NHPPAGDG_02218 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHPPAGDG_02219 7.9e-109 yhbD K Protein of unknown function (DUF4004)
NHPPAGDG_02220 3.5e-57 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NHPPAGDG_02221 9.4e-71 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NHPPAGDG_02222 0.0 prkA T Ser protein kinase
NHPPAGDG_02223 2.5e-225 yhbH S Belongs to the UPF0229 family
NHPPAGDG_02224 2.4e-75 yhbI K DNA-binding transcription factor activity
NHPPAGDG_02225 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NHPPAGDG_02226 3.1e-271 yhcA EGP Major facilitator Superfamily
NHPPAGDG_02227 5.2e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NHPPAGDG_02228 2.8e-37 yhcC
NHPPAGDG_02229 4.6e-55
NHPPAGDG_02230 6.6e-60 yhcF K Transcriptional regulator
NHPPAGDG_02231 8.8e-122 yhcG V ABC transporter, ATP-binding protein
NHPPAGDG_02232 2.6e-166 yhcH V ABC transporter, ATP-binding protein
NHPPAGDG_02233 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHPPAGDG_02234 1e-30 cspB K Cold-shock protein
NHPPAGDG_02235 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
NHPPAGDG_02236 8.4e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NHPPAGDG_02237 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHPPAGDG_02238 4.9e-41 yhcM
NHPPAGDG_02239 2.1e-61 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHPPAGDG_02240 1e-158 yhcP
NHPPAGDG_02241 1.6e-96 yhcQ M Spore coat protein
NHPPAGDG_02242 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NHPPAGDG_02243 1.1e-101 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NHPPAGDG_02244 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHPPAGDG_02245 9.3e-68 yhcU S Family of unknown function (DUF5365)
NHPPAGDG_02246 3.8e-67 yhcV S COG0517 FOG CBS domain
NHPPAGDG_02247 1e-119 yhcW 5.4.2.6 S hydrolase
NHPPAGDG_02248 2.3e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHPPAGDG_02249 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHPPAGDG_02250 3.4e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NHPPAGDG_02251 1.4e-150 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NHPPAGDG_02252 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHPPAGDG_02253 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NHPPAGDG_02254 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NHPPAGDG_02255 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
NHPPAGDG_02256 2e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPPAGDG_02257 7.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
NHPPAGDG_02258 3.6e-38 yhdB S YhdB-like protein
NHPPAGDG_02259 1.8e-53 yhdC S Protein of unknown function (DUF3889)
NHPPAGDG_02260 1e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NHPPAGDG_02261 1e-75 nsrR K Transcriptional regulator
NHPPAGDG_02262 9.6e-238 ygxB M Conserved TM helix
NHPPAGDG_02263 2e-261 ycgB S Stage V sporulation protein R
NHPPAGDG_02264 1.5e-250 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NHPPAGDG_02265 7.2e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NHPPAGDG_02266 3.8e-162 citR K Transcriptional regulator
NHPPAGDG_02267 1.3e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
NHPPAGDG_02268 6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPPAGDG_02269 7.6e-250 yhdG E amino acid
NHPPAGDG_02270 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NHPPAGDG_02271 2.1e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPPAGDG_02272 5.9e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPPAGDG_02273 8.1e-45 yhdK S Sigma-M inhibitor protein
NHPPAGDG_02274 6.6e-201 yhdL S Sigma factor regulator N-terminal
NHPPAGDG_02275 1e-84 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_02276 8.3e-190 yhdN C Aldo keto reductase
NHPPAGDG_02277 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NHPPAGDG_02278 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
NHPPAGDG_02280 2.8e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NHPPAGDG_02281 4.2e-29 S Domain of unknown function (DUF4177)
NHPPAGDG_02282 6.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHPPAGDG_02283 1.3e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NHPPAGDG_02284 4.8e-51 yjdF S Protein of unknown function (DUF2992)
NHPPAGDG_02285 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHPPAGDG_02286 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NHPPAGDG_02287 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NHPPAGDG_02289 5.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
NHPPAGDG_02290 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
NHPPAGDG_02292 9e-19
NHPPAGDG_02293 2.1e-35
NHPPAGDG_02295 1.8e-42 S Super-infection exclusion protein B
NHPPAGDG_02300 1.4e-15 K Cro/C1-type HTH DNA-binding domain
NHPPAGDG_02305 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NHPPAGDG_02306 4.6e-123 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHPPAGDG_02307 5.1e-129 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHPPAGDG_02308 1e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NHPPAGDG_02310 4.4e-97 yqjB S protein conserved in bacteria
NHPPAGDG_02311 1.7e-171 yqjA S Putative aromatic acid exporter C-terminal domain
NHPPAGDG_02312 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NHPPAGDG_02313 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NHPPAGDG_02314 1.8e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
NHPPAGDG_02315 9.3e-77 yqiW S Belongs to the UPF0403 family
NHPPAGDG_02316 3.4e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHPPAGDG_02317 7.9e-208 norA EGP Major facilitator Superfamily
NHPPAGDG_02318 1.7e-151 bmrR K helix_turn_helix, mercury resistance
NHPPAGDG_02319 7.5e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHPPAGDG_02320 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHPPAGDG_02321 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHPPAGDG_02322 6.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHPPAGDG_02323 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NHPPAGDG_02324 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NHPPAGDG_02325 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NHPPAGDG_02326 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NHPPAGDG_02327 4e-34 yqzF S Protein of unknown function (DUF2627)
NHPPAGDG_02328 8.7e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NHPPAGDG_02329 8.2e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NHPPAGDG_02330 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NHPPAGDG_02331 6.7e-212 mmgC I acyl-CoA dehydrogenase
NHPPAGDG_02332 2.6e-155 hbdA 1.1.1.157 I Dehydrogenase
NHPPAGDG_02333 1.3e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
NHPPAGDG_02334 2.3e-128 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NHPPAGDG_02335 8.6e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NHPPAGDG_02336 6e-27
NHPPAGDG_02338 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NHPPAGDG_02340 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NHPPAGDG_02341 2.3e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
NHPPAGDG_02342 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
NHPPAGDG_02343 6.6e-78 argR K Regulates arginine biosynthesis genes
NHPPAGDG_02344 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NHPPAGDG_02345 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHPPAGDG_02346 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHPPAGDG_02347 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHPPAGDG_02348 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHPPAGDG_02349 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHPPAGDG_02350 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHPPAGDG_02351 8.1e-67 yqhY S protein conserved in bacteria
NHPPAGDG_02352 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NHPPAGDG_02353 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHPPAGDG_02354 2.9e-90 spoIIIAH S SpoIIIAH-like protein
NHPPAGDG_02355 2.2e-109 spoIIIAG S stage III sporulation protein AG
NHPPAGDG_02356 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NHPPAGDG_02357 1.3e-197 spoIIIAE S stage III sporulation protein AE
NHPPAGDG_02358 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NHPPAGDG_02359 7.6e-29 spoIIIAC S stage III sporulation protein AC
NHPPAGDG_02360 1.1e-84 spoIIIAB S Stage III sporulation protein
NHPPAGDG_02361 4e-170 spoIIIAA S stage III sporulation protein AA
NHPPAGDG_02362 1.8e-36 yqhV S Protein of unknown function (DUF2619)
NHPPAGDG_02363 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHPPAGDG_02364 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NHPPAGDG_02365 1.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NHPPAGDG_02366 6.6e-93 yqhR S Conserved membrane protein YqhR
NHPPAGDG_02367 1.4e-173 yqhQ S Protein of unknown function (DUF1385)
NHPPAGDG_02368 2.2e-61 yqhP
NHPPAGDG_02369 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
NHPPAGDG_02370 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NHPPAGDG_02371 1.3e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NHPPAGDG_02372 3.3e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
NHPPAGDG_02373 9.1e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NHPPAGDG_02374 5.5e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NHPPAGDG_02375 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NHPPAGDG_02376 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NHPPAGDG_02377 1.6e-151 yqhG S Bacterial protein YqhG of unknown function
NHPPAGDG_02378 1.2e-24 sinI S Anti-repressor SinI
NHPPAGDG_02379 1e-54 sinR K transcriptional
NHPPAGDG_02380 4.3e-141 tasA S Cell division protein FtsN
NHPPAGDG_02381 5.7e-58 sipW 3.4.21.89 U Signal peptidase
NHPPAGDG_02382 4.8e-97 yqxM
NHPPAGDG_02383 2.8e-53 yqzG S Protein of unknown function (DUF3889)
NHPPAGDG_02384 5.2e-26 yqzE S YqzE-like protein
NHPPAGDG_02385 1.2e-43 S ComG operon protein 7
NHPPAGDG_02386 6e-45 comGF U Putative Competence protein ComGF
NHPPAGDG_02387 1.3e-57 comGE
NHPPAGDG_02388 1.3e-67 gspH NU protein transport across the cell outer membrane
NHPPAGDG_02389 1.2e-46 comGC U Required for transformation and DNA binding
NHPPAGDG_02390 1.4e-168 comGB NU COG1459 Type II secretory pathway, component PulF
NHPPAGDG_02391 5e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHPPAGDG_02392 1.5e-172 corA P Mg2 transporter protein
NHPPAGDG_02393 2.2e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NHPPAGDG_02394 1.5e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHPPAGDG_02396 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NHPPAGDG_02397 2e-36 yqgY S Protein of unknown function (DUF2626)
NHPPAGDG_02398 2.3e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NHPPAGDG_02399 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NHPPAGDG_02400 6.9e-50 yqgV S Thiamine-binding protein
NHPPAGDG_02401 8.8e-198 yqgU
NHPPAGDG_02402 1.6e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NHPPAGDG_02403 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NHPPAGDG_02404 5.8e-180 glcK 2.7.1.2 G Glucokinase
NHPPAGDG_02405 4.3e-33 yqgQ S Protein conserved in bacteria
NHPPAGDG_02406 1.3e-211 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NHPPAGDG_02407 2.5e-09 yqgO
NHPPAGDG_02408 6.7e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHPPAGDG_02409 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHPPAGDG_02410 1.2e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NHPPAGDG_02412 9.2e-51 yqzD
NHPPAGDG_02413 2.1e-71 yqzC S YceG-like family
NHPPAGDG_02414 6.4e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHPPAGDG_02415 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHPPAGDG_02416 8.2e-157 pstA P Phosphate transport system permease
NHPPAGDG_02417 9.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NHPPAGDG_02418 2.9e-148 pstS P Phosphate
NHPPAGDG_02419 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NHPPAGDG_02420 1.8e-229 yqgE EGP Major facilitator superfamily
NHPPAGDG_02421 3.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NHPPAGDG_02422 4e-73 yqgC S protein conserved in bacteria
NHPPAGDG_02423 3.9e-131 yqgB S Protein of unknown function (DUF1189)
NHPPAGDG_02424 4.4e-46 yqfZ M LysM domain
NHPPAGDG_02425 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NHPPAGDG_02426 2.8e-61 yqfX S membrane
NHPPAGDG_02427 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NHPPAGDG_02428 1.9e-77 zur P Belongs to the Fur family
NHPPAGDG_02429 8.2e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NHPPAGDG_02430 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NHPPAGDG_02431 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NHPPAGDG_02432 8.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHPPAGDG_02434 2.9e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NHPPAGDG_02435 2.6e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHPPAGDG_02436 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
NHPPAGDG_02437 2.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NHPPAGDG_02438 4.4e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHPPAGDG_02439 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHPPAGDG_02440 7.7e-88 yaiI S Belongs to the UPF0178 family
NHPPAGDG_02441 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NHPPAGDG_02442 4.5e-112 ccpN K CBS domain
NHPPAGDG_02443 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NHPPAGDG_02444 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NHPPAGDG_02445 9e-144 recO L Involved in DNA repair and RecF pathway recombination
NHPPAGDG_02446 8.4e-19 S YqzL-like protein
NHPPAGDG_02447 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHPPAGDG_02448 3.5e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NHPPAGDG_02449 4.3e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NHPPAGDG_02450 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHPPAGDG_02451 0.0 yqfF S membrane-associated HD superfamily hydrolase
NHPPAGDG_02453 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NHPPAGDG_02454 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NHPPAGDG_02455 2.7e-45 yqfC S sporulation protein YqfC
NHPPAGDG_02456 1.1e-21 yqfB
NHPPAGDG_02457 6.3e-121 yqfA S UPF0365 protein
NHPPAGDG_02458 1e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NHPPAGDG_02459 1.4e-64 yqeY S Yqey-like protein
NHPPAGDG_02460 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NHPPAGDG_02461 1.1e-156 yqeW P COG1283 Na phosphate symporter
NHPPAGDG_02462 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NHPPAGDG_02463 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHPPAGDG_02464 5.4e-175 prmA J Methylates ribosomal protein L11
NHPPAGDG_02465 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHPPAGDG_02466 0.0 dnaK O Heat shock 70 kDa protein
NHPPAGDG_02467 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHPPAGDG_02468 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHPPAGDG_02469 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
NHPPAGDG_02470 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHPPAGDG_02471 7.2e-53 yqxA S Protein of unknown function (DUF3679)
NHPPAGDG_02472 9.9e-222 spoIIP M stage II sporulation protein P
NHPPAGDG_02473 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NHPPAGDG_02474 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NHPPAGDG_02475 6.2e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
NHPPAGDG_02476 4.1e-15 S YqzM-like protein
NHPPAGDG_02477 0.0 comEC S Competence protein ComEC
NHPPAGDG_02478 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NHPPAGDG_02479 3.3e-104 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NHPPAGDG_02480 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHPPAGDG_02481 3.2e-138 yqeM Q Methyltransferase
NHPPAGDG_02482 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHPPAGDG_02483 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NHPPAGDG_02484 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHPPAGDG_02485 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NHPPAGDG_02486 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHPPAGDG_02487 1.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NHPPAGDG_02488 5.3e-95 yqeG S hydrolase of the HAD superfamily
NHPPAGDG_02490 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NHPPAGDG_02491 5.4e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPPAGDG_02492 1.8e-105 yqeD S SNARE associated Golgi protein
NHPPAGDG_02493 4.2e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NHPPAGDG_02494 1.8e-130 yqeB
NHPPAGDG_02495 1.6e-35 nucB M Deoxyribonuclease NucA/NucB
NHPPAGDG_02496 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPPAGDG_02497 3.5e-42 S Putative amidase domain
NHPPAGDG_02498 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NHPPAGDG_02499 3.2e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NHPPAGDG_02500 1.1e-07 ywnC S Family of unknown function (DUF5362)
NHPPAGDG_02501 3.2e-69 ywnF S Family of unknown function (DUF5392)
NHPPAGDG_02502 2.7e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHPPAGDG_02503 5.9e-143 mta K transcriptional
NHPPAGDG_02504 1.7e-58 ywnC S Family of unknown function (DUF5362)
NHPPAGDG_02505 4.2e-110 ywnB S NAD(P)H-binding
NHPPAGDG_02506 1.7e-64 ywnA K Transcriptional regulator
NHPPAGDG_02507 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NHPPAGDG_02508 1.6e-61 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NHPPAGDG_02509 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NHPPAGDG_02510 1.4e-111 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NHPPAGDG_02511 1.4e-120 urtD S ATPases associated with a variety of cellular activities
NHPPAGDG_02512 3.6e-183 urtC E Belongs to the binding-protein-dependent transport system permease family
NHPPAGDG_02513 4.6e-147 urtB E Belongs to the binding-protein-dependent transport system permease family
NHPPAGDG_02514 2.2e-219 urtA E Receptor family ligand binding region
NHPPAGDG_02515 3.6e-09 csbD K CsbD-like
NHPPAGDG_02516 5.1e-84 ywmF S Peptidase M50
NHPPAGDG_02517 7.9e-104 S response regulator aspartate phosphatase
NHPPAGDG_02518 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NHPPAGDG_02519 2.9e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NHPPAGDG_02521 2.7e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NHPPAGDG_02522 3.3e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NHPPAGDG_02523 9.8e-178 spoIID D Stage II sporulation protein D
NHPPAGDG_02524 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHPPAGDG_02525 3.4e-132 ywmB S TATA-box binding
NHPPAGDG_02526 1.3e-32 ywzB S membrane
NHPPAGDG_02527 4.8e-87 ywmA
NHPPAGDG_02528 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NHPPAGDG_02529 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHPPAGDG_02530 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHPPAGDG_02531 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHPPAGDG_02532 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHPPAGDG_02533 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHPPAGDG_02534 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHPPAGDG_02535 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NHPPAGDG_02536 2.5e-62 atpI S ATP synthase
NHPPAGDG_02537 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHPPAGDG_02538 6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHPPAGDG_02539 2.4e-47 yxcD S Protein of unknown function (DUF2653)
NHPPAGDG_02541 8.3e-176 iolS C Aldo keto reductase
NHPPAGDG_02542 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NHPPAGDG_02543 1.5e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHPPAGDG_02544 2.3e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NHPPAGDG_02545 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NHPPAGDG_02546 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NHPPAGDG_02547 8.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NHPPAGDG_02548 6.2e-233 iolF EGP Major facilitator Superfamily
NHPPAGDG_02549 1.8e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NHPPAGDG_02550 3.3e-166 iolH G Xylose isomerase-like TIM barrel
NHPPAGDG_02551 2.1e-146 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NHPPAGDG_02552 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NHPPAGDG_02553 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_02554 4e-181 T PhoQ Sensor
NHPPAGDG_02555 9.7e-138 yxdL V ABC transporter, ATP-binding protein
NHPPAGDG_02556 0.0 yxdM V ABC transporter (permease)
NHPPAGDG_02557 1.5e-58 yxeA S Protein of unknown function (DUF1093)
NHPPAGDG_02558 2.3e-176 fhuD P ABC transporter
NHPPAGDG_02559 8.5e-69
NHPPAGDG_02560 5.6e-16 yxeD
NHPPAGDG_02561 1.3e-20 yxeE
NHPPAGDG_02564 1.4e-150 yidA S hydrolases of the HAD superfamily
NHPPAGDG_02565 5.9e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NHPPAGDG_02566 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPPAGDG_02567 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPPAGDG_02568 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NHPPAGDG_02569 2.9e-106 yxeN P COG0765 ABC-type amino acid transport system, permease component
NHPPAGDG_02570 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NHPPAGDG_02571 2.7e-213 yxeP 3.5.1.47 E hydrolase activity
NHPPAGDG_02572 1.5e-247 yxeQ S MmgE/PrpD family
NHPPAGDG_02573 7.1e-198 eutH E Ethanolamine utilisation protein, EutH
NHPPAGDG_02574 2e-152 yxxB S Domain of Unknown Function (DUF1206)
NHPPAGDG_02575 1.8e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NHPPAGDG_02576 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHPPAGDG_02577 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NHPPAGDG_02578 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NHPPAGDG_02579 6.3e-249 lysP E amino acid
NHPPAGDG_02580 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NHPPAGDG_02581 1.7e-72 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NHPPAGDG_02582 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NHPPAGDG_02583 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
NHPPAGDG_02584 2.8e-76 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NHPPAGDG_02585 1.4e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NHPPAGDG_02586 6.4e-77 L NgoFVII restriction endonuclease
NHPPAGDG_02587 1.7e-96 S GTP binding
NHPPAGDG_02588 4.9e-183 2.1.1.37 H C-5 cytosine-specific DNA methylase
NHPPAGDG_02589 2.8e-49 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
NHPPAGDG_02590 1e-20 S Domain of unknown function (DUF5082)
NHPPAGDG_02591 4.7e-39 yxiC S Family of unknown function (DUF5344)
NHPPAGDG_02592 1.1e-303 S nuclease activity
NHPPAGDG_02593 1.1e-77 S SMI1 / KNR4 family
NHPPAGDG_02594 2.9e-40
NHPPAGDG_02595 5.9e-67 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHPPAGDG_02596 2.9e-173 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHPPAGDG_02597 1.1e-72 yxiE T Belongs to the universal stress protein A family
NHPPAGDG_02598 1.4e-162 yxxF EG EamA-like transporter family
NHPPAGDG_02599 0.0 wapA M COG3209 Rhs family protein
NHPPAGDG_02600 7e-55
NHPPAGDG_02602 7.2e-139
NHPPAGDG_02603 4e-93 S Protein of unknown function (DUF4240)
NHPPAGDG_02604 4.9e-76
NHPPAGDG_02605 8.4e-45
NHPPAGDG_02606 4.3e-68 yxiG
NHPPAGDG_02607 3.4e-52 yxxG
NHPPAGDG_02608 1.9e-38 S Protein of unknown function (DUF2750)
NHPPAGDG_02609 5.3e-16 yxiG
NHPPAGDG_02610 8.3e-13 yxiG
NHPPAGDG_02611 6.5e-135
NHPPAGDG_02612 3.9e-84 yxiI S Protein of unknown function (DUF2716)
NHPPAGDG_02613 7.7e-43 yxiJ S YxiJ-like protein
NHPPAGDG_02616 6.6e-215 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NHPPAGDG_02617 8.1e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NHPPAGDG_02618 6.8e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
NHPPAGDG_02619 4e-111
NHPPAGDG_02620 8.8e-139 licT K transcriptional antiterminator
NHPPAGDG_02621 3.3e-143 exoK GH16 M licheninase activity
NHPPAGDG_02622 6.6e-224 citH C Citrate transporter
NHPPAGDG_02623 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NHPPAGDG_02624 3e-47 yxiS
NHPPAGDG_02625 8.3e-103 T Domain of unknown function (DUF4163)
NHPPAGDG_02626 2.1e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NHPPAGDG_02627 1.8e-50 L Transposase and inactivated derivatives, TnpA family
NHPPAGDG_02628 3.5e-271 sufB O FeS cluster assembly
NHPPAGDG_02629 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NHPPAGDG_02630 7.9e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHPPAGDG_02631 9.1e-245 sufD O assembly protein SufD
NHPPAGDG_02632 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NHPPAGDG_02633 5.6e-46 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHPPAGDG_02634 1.8e-145 metQ P Belongs to the NlpA lipoprotein family
NHPPAGDG_02635 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NHPPAGDG_02636 2.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHPPAGDG_02637 3.2e-56 yusD S SCP-2 sterol transfer family
NHPPAGDG_02638 1.2e-54 traF CO Thioredoxin
NHPPAGDG_02639 1.4e-72 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NHPPAGDG_02640 2.4e-39 yusG S Protein of unknown function (DUF2553)
NHPPAGDG_02641 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NHPPAGDG_02642 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NHPPAGDG_02643 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NHPPAGDG_02644 3.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NHPPAGDG_02645 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NHPPAGDG_02646 8.1e-09 S YuzL-like protein
NHPPAGDG_02647 1.2e-163 fadM E Proline dehydrogenase
NHPPAGDG_02648 5.1e-40
NHPPAGDG_02649 1.6e-52 yusN M Coat F domain
NHPPAGDG_02650 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
NHPPAGDG_02651 4.2e-292 yusP P Major facilitator superfamily
NHPPAGDG_02652 1.8e-63 yusQ S Tautomerase enzyme
NHPPAGDG_02653 2.9e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPPAGDG_02654 8.2e-157 yusT K LysR substrate binding domain
NHPPAGDG_02655 6.6e-47 yusU S Protein of unknown function (DUF2573)
NHPPAGDG_02656 1e-153 yusV 3.6.3.34 HP ABC transporter
NHPPAGDG_02657 3.3e-66 S YusW-like protein
NHPPAGDG_02658 1.6e-300 pepF2 E COG1164 Oligoendopeptidase F
NHPPAGDG_02659 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPPAGDG_02660 2.7e-79 dps P Ferritin-like domain
NHPPAGDG_02661 4.4e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHPPAGDG_02662 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_02663 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
NHPPAGDG_02664 4.8e-157 yuxN K Transcriptional regulator
NHPPAGDG_02665 2.8e-260 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHPPAGDG_02666 8.6e-24 S Protein of unknown function (DUF3970)
NHPPAGDG_02667 5.9e-245 gerAA EG Spore germination protein
NHPPAGDG_02668 3.8e-196 gerAB E Spore germination protein
NHPPAGDG_02669 5e-183 gerAC S Spore germination B3/ GerAC like, C-terminal
NHPPAGDG_02670 6.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPPAGDG_02671 1.6e-186 vraS 2.7.13.3 T Histidine kinase
NHPPAGDG_02672 1.2e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NHPPAGDG_02673 3.1e-116 liaG S Putative adhesin
NHPPAGDG_02674 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NHPPAGDG_02675 7.3e-62 liaI S membrane
NHPPAGDG_02676 5.9e-225 yvqJ EGP Major facilitator Superfamily
NHPPAGDG_02677 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
NHPPAGDG_02678 2.7e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NHPPAGDG_02679 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_02680 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NHPPAGDG_02681 7.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPPAGDG_02682 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NHPPAGDG_02683 0.0 T PhoQ Sensor
NHPPAGDG_02684 8.1e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_02685 3.6e-22
NHPPAGDG_02686 4e-96 yvrI K RNA polymerase
NHPPAGDG_02687 6.9e-19 S YvrJ protein family
NHPPAGDG_02688 3.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
NHPPAGDG_02689 1.3e-64 yvrL S Regulatory protein YrvL
NHPPAGDG_02690 9e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NHPPAGDG_02691 2.1e-123 macB V ABC transporter, ATP-binding protein
NHPPAGDG_02692 6.9e-175 M Efflux transporter rnd family, mfp subunit
NHPPAGDG_02693 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NHPPAGDG_02694 4.5e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_02695 1.3e-180 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_02696 2.6e-177 fhuD P ABC transporter
NHPPAGDG_02697 4.9e-236 yvsH E Arginine ornithine antiporter
NHPPAGDG_02698 6.5e-16 S Small spore protein J (Spore_SspJ)
NHPPAGDG_02699 2.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NHPPAGDG_02700 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NHPPAGDG_02701 2e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NHPPAGDG_02702 1.4e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NHPPAGDG_02703 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NHPPAGDG_02704 3.2e-155 yvgN S reductase
NHPPAGDG_02705 5.4e-86 yvgO
NHPPAGDG_02706 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NHPPAGDG_02707 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NHPPAGDG_02708 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NHPPAGDG_02709 0.0 helD 3.6.4.12 L DNA helicase
NHPPAGDG_02710 4.1e-107 yvgT S membrane
NHPPAGDG_02711 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
NHPPAGDG_02712 2.7e-104 bdbD O Thioredoxin
NHPPAGDG_02713 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NHPPAGDG_02714 0.0 copA 3.6.3.54 P P-type ATPase
NHPPAGDG_02715 5.9e-29 copZ P Copper resistance protein CopZ
NHPPAGDG_02716 4.8e-48 csoR S transcriptional
NHPPAGDG_02717 1.1e-195 yvaA 1.1.1.371 S Oxidoreductase
NHPPAGDG_02718 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHPPAGDG_02719 0.0 yvaC S Fusaric acid resistance protein-like
NHPPAGDG_02720 1.3e-72 yvaD S Family of unknown function (DUF5360)
NHPPAGDG_02721 2.4e-54 yvaE P Small Multidrug Resistance protein
NHPPAGDG_02722 4.3e-98 K Bacterial regulatory proteins, tetR family
NHPPAGDG_02723 1e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPPAGDG_02725 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NHPPAGDG_02726 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHPPAGDG_02727 9.6e-143 est 3.1.1.1 S Carboxylesterase
NHPPAGDG_02728 2.4e-23 secG U Preprotein translocase subunit SecG
NHPPAGDG_02729 1.5e-151 yvaM S Serine aminopeptidase, S33
NHPPAGDG_02730 9.8e-36 yvzC K Transcriptional
NHPPAGDG_02731 4e-69 K transcriptional
NHPPAGDG_02732 1.2e-68 yvaO K Cro/C1-type HTH DNA-binding domain
NHPPAGDG_02733 2.2e-54 yodB K transcriptional
NHPPAGDG_02734 1.2e-19 NT chemotaxis protein
NHPPAGDG_02735 2.2e-170 NT chemotaxis protein
NHPPAGDG_02736 3.5e-95 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NHPPAGDG_02737 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NHPPAGDG_02738 1.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NHPPAGDG_02739 2.7e-208 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NHPPAGDG_02740 7.4e-60 yvbF K Belongs to the GbsR family
NHPPAGDG_02741 7.9e-13 S Sporulation delaying protein SdpA
NHPPAGDG_02742 4.9e-171
NHPPAGDG_02743 4.4e-08
NHPPAGDG_02744 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NHPPAGDG_02745 4.5e-45 sdpR K transcriptional
NHPPAGDG_02746 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NHPPAGDG_02747 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NHPPAGDG_02748 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NHPPAGDG_02749 8.4e-48 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NHPPAGDG_02750 2.7e-155 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NHPPAGDG_02751 3.5e-97 yvbF K Belongs to the GbsR family
NHPPAGDG_02752 6e-101 yvbG U UPF0056 membrane protein
NHPPAGDG_02753 1.9e-112 yvbH S YvbH-like oligomerisation region
NHPPAGDG_02754 5.2e-122 exoY M Membrane
NHPPAGDG_02755 0.0 tcaA S response to antibiotic
NHPPAGDG_02756 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
NHPPAGDG_02757 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHPPAGDG_02758 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NHPPAGDG_02759 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHPPAGDG_02760 8.5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NHPPAGDG_02761 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHPPAGDG_02762 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NHPPAGDG_02763 1.6e-252 araE EGP Major facilitator Superfamily
NHPPAGDG_02764 4.6e-202 araR K transcriptional
NHPPAGDG_02765 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPPAGDG_02766 1.6e-157 yvbU K Transcriptional regulator
NHPPAGDG_02767 1.6e-155 yvbV EG EamA-like transporter family
NHPPAGDG_02768 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NHPPAGDG_02769 2.6e-194 yvbX S Glycosyl hydrolase
NHPPAGDG_02770 6.7e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NHPPAGDG_02771 3.5e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NHPPAGDG_02772 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NHPPAGDG_02773 5.8e-29 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPPAGDG_02774 2.7e-154 rsbQ S Alpha/beta hydrolase family
NHPPAGDG_02775 2.7e-195 rsbU 3.1.3.3 T response regulator
NHPPAGDG_02776 3.2e-250 galA 3.2.1.89 G arabinogalactan
NHPPAGDG_02777 0.0 lacA 3.2.1.23 G beta-galactosidase
NHPPAGDG_02778 2.7e-149 ganQ P transport
NHPPAGDG_02779 1e-96 malC P COG1175 ABC-type sugar transport systems, permease components
NHPPAGDG_02780 5.3e-117 malC P COG1175 ABC-type sugar transport systems, permease components
NHPPAGDG_02781 4.1e-195 cycB G COG2182 Maltose-binding periplasmic proteins domains
NHPPAGDG_02782 1.8e-184 lacR K Transcriptional regulator
NHPPAGDG_02783 1e-112 yvfI K COG2186 Transcriptional regulators
NHPPAGDG_02784 8.8e-309 yvfH C L-lactate permease
NHPPAGDG_02785 3.9e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NHPPAGDG_02786 1e-31 yvfG S YvfG protein
NHPPAGDG_02787 2.9e-187 yvfF GM Exopolysaccharide biosynthesis protein
NHPPAGDG_02788 1.5e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NHPPAGDG_02789 2.1e-56 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NHPPAGDG_02790 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NHPPAGDG_02791 7.8e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPPAGDG_02792 1e-190 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPPAGDG_02793 2.2e-204 epsI GM pyruvyl transferase
NHPPAGDG_02794 1.7e-193 epsH GT2 S Glycosyltransferase like family 2
NHPPAGDG_02795 1.6e-205 epsG S EpsG family
NHPPAGDG_02796 2.9e-218 epsF GT4 M Glycosyl transferases group 1
NHPPAGDG_02797 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPPAGDG_02798 1.2e-221 epsD GT4 M Glycosyl transferase 4-like
NHPPAGDG_02799 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NHPPAGDG_02800 3.9e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NHPPAGDG_02801 4e-122 ywqC M biosynthesis protein
NHPPAGDG_02802 3.1e-75 slr K transcriptional
NHPPAGDG_02803 5.3e-278 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NHPPAGDG_02805 4.6e-93 padC Q Phenolic acid decarboxylase
NHPPAGDG_02806 1.9e-46 MA20_18690 S Protein of unknown function (DUF3237)
NHPPAGDG_02807 3e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NHPPAGDG_02808 1.4e-261 pbpE V Beta-lactamase
NHPPAGDG_02809 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NHPPAGDG_02810 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NHPPAGDG_02811 3.3e-120 yveA E amino acid
NHPPAGDG_02812 2.7e-137 yveA E amino acid
NHPPAGDG_02813 7.4e-106 yvdT K Transcriptional regulator
NHPPAGDG_02814 4.3e-50 ykkC P Small Multidrug Resistance protein
NHPPAGDG_02815 7.1e-50 sugE P Small Multidrug Resistance protein
NHPPAGDG_02816 3e-72 yvdQ S Protein of unknown function (DUF3231)
NHPPAGDG_02818 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHPPAGDG_02819 1.3e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NHPPAGDG_02820 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NHPPAGDG_02821 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NHPPAGDG_02822 5e-154 malA S Protein of unknown function (DUF1189)
NHPPAGDG_02823 3.9e-148 malD P transport
NHPPAGDG_02824 8.5e-243 malC P COG1175 ABC-type sugar transport systems, permease components
NHPPAGDG_02825 5.3e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NHPPAGDG_02826 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NHPPAGDG_02827 6.1e-174 yvdE K Transcriptional regulator
NHPPAGDG_02828 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
NHPPAGDG_02829 8.4e-41 yvdC S MazG nucleotide pyrophosphohydrolase domain
NHPPAGDG_02830 1.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NHPPAGDG_02831 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NHPPAGDG_02832 8.7e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPPAGDG_02833 0.0 yxdM V ABC transporter (permease)
NHPPAGDG_02834 2.1e-140 yvcR V ABC transporter, ATP-binding protein
NHPPAGDG_02835 2.6e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NHPPAGDG_02836 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_02837 5.5e-21
NHPPAGDG_02838 8.3e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NHPPAGDG_02839 1.6e-36 crh G Phosphocarrier protein Chr
NHPPAGDG_02840 1.4e-170 whiA K May be required for sporulation
NHPPAGDG_02841 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NHPPAGDG_02842 5.7e-166 rapZ S Displays ATPase and GTPase activities
NHPPAGDG_02843 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHPPAGDG_02844 9.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHPPAGDG_02845 1.1e-97 usp CBM50 M protein conserved in bacteria
NHPPAGDG_02846 4.5e-277 S COG0457 FOG TPR repeat
NHPPAGDG_02847 3.3e-83 msbA2 3.6.3.44 V ABC transporter
NHPPAGDG_02849 0.0
NHPPAGDG_02850 1.6e-118
NHPPAGDG_02851 8.8e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NHPPAGDG_02852 6.2e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHPPAGDG_02853 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NHPPAGDG_02854 4.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHPPAGDG_02855 1.8e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NHPPAGDG_02856 3.2e-226 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHPPAGDG_02857 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NHPPAGDG_02858 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NHPPAGDG_02859 2.3e-139 yvpB NU protein conserved in bacteria
NHPPAGDG_02860 9.3e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NHPPAGDG_02861 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NHPPAGDG_02862 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NHPPAGDG_02863 4.5e-161 yvoD P COG0370 Fe2 transport system protein B
NHPPAGDG_02864 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHPPAGDG_02865 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHPPAGDG_02866 6.4e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHPPAGDG_02867 2.3e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHPPAGDG_02868 3.6e-134 yvoA K transcriptional
NHPPAGDG_02869 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NHPPAGDG_02870 4.2e-83 adcR K helix_turn_helix multiple antibiotic resistance protein
NHPPAGDG_02871 3.8e-229 cypX 1.14.15.13 C Cytochrome P450
NHPPAGDG_02872 1.8e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NHPPAGDG_02873 7.4e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
NHPPAGDG_02874 2.7e-203 yvmA EGP Major facilitator Superfamily
NHPPAGDG_02875 1.2e-50 yvlD S Membrane
NHPPAGDG_02876 2.6e-26 pspB KT PspC domain
NHPPAGDG_02877 2.4e-166 yvlB S Putative adhesin
NHPPAGDG_02878 8e-49 yvlA
NHPPAGDG_02879 5.7e-33 yvkN
NHPPAGDG_02880 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NHPPAGDG_02881 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NHPPAGDG_02882 4.7e-194 gerM S COG5401 Spore germination protein
NHPPAGDG_02883 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NHPPAGDG_02884 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHPPAGDG_02885 4.1e-92 ysnB S Phosphoesterase
NHPPAGDG_02887 3.8e-132 ysnF S protein conserved in bacteria
NHPPAGDG_02888 1.8e-78 ysnE K acetyltransferase
NHPPAGDG_02890 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NHPPAGDG_02891 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NHPPAGDG_02892 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHPPAGDG_02893 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHPPAGDG_02894 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NHPPAGDG_02895 1.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHPPAGDG_02896 2.6e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHPPAGDG_02897 5.1e-187 ysoA H Tetratricopeptide repeat
NHPPAGDG_02898 1.6e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHPPAGDG_02899 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHPPAGDG_02900 1.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NHPPAGDG_02901 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NHPPAGDG_02902 5.7e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NHPPAGDG_02903 1.4e-89 ysxD
NHPPAGDG_02904 4.6e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NHPPAGDG_02905 3.6e-146 hemX O cytochrome C
NHPPAGDG_02906 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NHPPAGDG_02907 1.3e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NHPPAGDG_02908 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
NHPPAGDG_02909 1.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NHPPAGDG_02910 1.2e-210 spoVID M stage VI sporulation protein D
NHPPAGDG_02911 2.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NHPPAGDG_02912 1.6e-25
NHPPAGDG_02913 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHPPAGDG_02914 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHPPAGDG_02915 2.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NHPPAGDG_02916 4e-160 spoIIB S Sporulation related domain
NHPPAGDG_02917 2.8e-102 maf D septum formation protein Maf
NHPPAGDG_02918 1e-125 radC E Belongs to the UPF0758 family
NHPPAGDG_02919 1.8e-184 mreB D Rod shape-determining protein MreB
NHPPAGDG_02920 1.1e-156 mreC M Involved in formation and maintenance of cell shape
NHPPAGDG_02921 1.4e-84 mreD M shape-determining protein
NHPPAGDG_02922 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NHPPAGDG_02923 2.5e-144 minD D Belongs to the ParA family
NHPPAGDG_02924 5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NHPPAGDG_02925 1.6e-160 spoIVFB S Stage IV sporulation protein
NHPPAGDG_02926 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NHPPAGDG_02927 4.1e-56 ysxB J ribosomal protein
NHPPAGDG_02928 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NHPPAGDG_02929 7.4e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NHPPAGDG_02930 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHPPAGDG_02931 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NHPPAGDG_02932 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
NHPPAGDG_02933 8.7e-93 niaR S small molecule binding protein (contains 3H domain)
NHPPAGDG_02934 4.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
NHPPAGDG_02935 7e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NHPPAGDG_02936 4.4e-155 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NHPPAGDG_02937 9.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NHPPAGDG_02938 2.6e-134 safA M spore coat assembly protein SafA
NHPPAGDG_02939 6e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHPPAGDG_02940 6.1e-126 yebC K transcriptional regulatory protein
NHPPAGDG_02941 4.5e-261 alsT E Sodium alanine symporter
NHPPAGDG_02942 4e-51 S Family of unknown function (DUF5412)
NHPPAGDG_02944 7.9e-117 yrzF T serine threonine protein kinase
NHPPAGDG_02945 2.2e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NHPPAGDG_02946 2e-252 csbX EGP Major facilitator Superfamily
NHPPAGDG_02947 1.1e-92 bofC S BofC C-terminal domain
NHPPAGDG_02948 4.5e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHPPAGDG_02949 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHPPAGDG_02950 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NHPPAGDG_02951 5.7e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHPPAGDG_02952 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHPPAGDG_02953 8e-39 yajC U Preprotein translocase subunit YajC
NHPPAGDG_02954 3.8e-73 yrzE S Protein of unknown function (DUF3792)
NHPPAGDG_02955 6.6e-111 yrbG S membrane
NHPPAGDG_02956 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPPAGDG_02957 1.6e-48 yrzD S Post-transcriptional regulator
NHPPAGDG_02958 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NHPPAGDG_02959 1.1e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NHPPAGDG_02960 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NHPPAGDG_02961 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NHPPAGDG_02962 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHPPAGDG_02963 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHPPAGDG_02964 1.9e-69 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHPPAGDG_02965 5.9e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
NHPPAGDG_02967 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NHPPAGDG_02968 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NHPPAGDG_02969 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NHPPAGDG_02970 5.8e-95 rok K Repressor of ComK
NHPPAGDG_02971 7e-80 ykuV CO thiol-disulfide
NHPPAGDG_02972 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NHPPAGDG_02973 8.8e-142 ykuT M Mechanosensitive ion channel
NHPPAGDG_02974 9e-37 ykuS S Belongs to the UPF0180 family
NHPPAGDG_02975 8.4e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHPPAGDG_02976 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHPPAGDG_02977 8.7e-78 fld C Flavodoxin
NHPPAGDG_02978 2.6e-174 ykuO
NHPPAGDG_02979 4.2e-83 fld C Flavodoxin domain
NHPPAGDG_02980 3.5e-168 ccpC K Transcriptional regulator
NHPPAGDG_02981 2.1e-76 ykuL S CBS domain
NHPPAGDG_02982 3.9e-27 ykzF S Antirepressor AbbA
NHPPAGDG_02983 4.4e-94 ykuK S Ribonuclease H-like
NHPPAGDG_02984 3.9e-37 ykuJ S protein conserved in bacteria
NHPPAGDG_02986 3.3e-233 ykuI T Diguanylate phosphodiesterase
NHPPAGDG_02988 0.0 3.2.1.132 M Putative peptidoglycan binding domain
NHPPAGDG_02989 6.4e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPPAGDG_02990 1.6e-165 ykuE S Metallophosphoesterase
NHPPAGDG_02991 1.5e-86 ykuD S protein conserved in bacteria
NHPPAGDG_02992 4.8e-238 ykuC EGP Major facilitator Superfamily
NHPPAGDG_02993 1.7e-84 ykyB S YkyB-like protein
NHPPAGDG_02994 2.4e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
NHPPAGDG_02995 2.2e-15
NHPPAGDG_02996 3.7e-221 patA 2.6.1.1 E Aminotransferase
NHPPAGDG_02997 0.0 pilS 2.7.13.3 T Histidine kinase
NHPPAGDG_02998 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NHPPAGDG_02999 7.5e-108 ykwD J protein with SCP PR1 domains
NHPPAGDG_03000 3.4e-31 csfB S Inhibitor of sigma-G Gin
NHPPAGDG_03001 2e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NHPPAGDG_03002 9.9e-203 yaaN P Belongs to the TelA family
NHPPAGDG_03003 4.8e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NHPPAGDG_03004 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHPPAGDG_03005 2.2e-54 yaaQ S protein conserved in bacteria
NHPPAGDG_03006 1e-70 yaaR S protein conserved in bacteria
NHPPAGDG_03007 1.1e-181 holB 2.7.7.7 L DNA polymerase III
NHPPAGDG_03008 6.1e-146 yaaT S stage 0 sporulation protein
NHPPAGDG_03009 4.8e-31 yabA L Involved in initiation control of chromosome replication
NHPPAGDG_03010 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NHPPAGDG_03011 1.5e-49 yazA L endonuclease containing a URI domain
NHPPAGDG_03012 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHPPAGDG_03013 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NHPPAGDG_03014 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHPPAGDG_03015 3.8e-142 tatD L hydrolase, TatD
NHPPAGDG_03016 5.8e-167 rpfB GH23 T protein conserved in bacteria
NHPPAGDG_03017 7.9e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHPPAGDG_03018 4.2e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHPPAGDG_03019 1.6e-136 yabG S peptidase
NHPPAGDG_03020 7.8e-39 veg S protein conserved in bacteria
NHPPAGDG_03021 2e-26 sspF S DNA topological change
NHPPAGDG_03022 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NHPPAGDG_03023 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NHPPAGDG_03024 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NHPPAGDG_03025 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NHPPAGDG_03026 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHPPAGDG_03027 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHPPAGDG_03028 4.3e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NHPPAGDG_03029 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHPPAGDG_03030 2.4e-39 yabK S Peptide ABC transporter permease
NHPPAGDG_03031 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHPPAGDG_03032 1.5e-92 spoVT K stage V sporulation protein
NHPPAGDG_03033 7.8e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPPAGDG_03034 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NHPPAGDG_03035 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NHPPAGDG_03036 1.5e-49 yabP S Sporulation protein YabP
NHPPAGDG_03037 4.3e-107 yabQ S spore cortex biosynthesis protein
NHPPAGDG_03038 1.1e-44 divIC D Septum formation initiator
NHPPAGDG_03039 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NHPPAGDG_03041 4.8e-123 yrpD S Domain of unknown function, YrpD
NHPPAGDG_03043 1.3e-113 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NHPPAGDG_03044 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_03045 1.7e-187 yrpG C Aldo/keto reductase family
NHPPAGDG_03046 9.5e-226 yraO C Citrate transporter
NHPPAGDG_03047 3.4e-163 yraN K Transcriptional regulator
NHPPAGDG_03048 5.9e-205 yraM S PrpF protein
NHPPAGDG_03049 1.1e-14 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NHPPAGDG_03050 3.2e-37 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPPAGDG_03051 4.7e-151 S Alpha beta hydrolase
NHPPAGDG_03052 0.0 levR K PTS system fructose IIA component
NHPPAGDG_03053 6.2e-252 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NHPPAGDG_03054 1.4e-105 yrhP E LysE type translocator
NHPPAGDG_03055 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
NHPPAGDG_03056 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NHPPAGDG_03057 7.2e-150 rsiV S Protein of unknown function (DUF3298)
NHPPAGDG_03058 0.0 yrhL I Acyltransferase family
NHPPAGDG_03059 9e-44 yrhK S YrhK-like protein
NHPPAGDG_03060 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NHPPAGDG_03061 6.5e-96 yrhH Q methyltransferase
NHPPAGDG_03064 1.5e-141 focA P Formate nitrite
NHPPAGDG_03065 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
NHPPAGDG_03066 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NHPPAGDG_03067 2.4e-78 yrhD S Protein of unknown function (DUF1641)
NHPPAGDG_03068 1.8e-34 yrhC S YrhC-like protein
NHPPAGDG_03069 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NHPPAGDG_03070 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NHPPAGDG_03071 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHPPAGDG_03072 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NHPPAGDG_03073 3.5e-26 yrzA S Protein of unknown function (DUF2536)
NHPPAGDG_03074 4.2e-63 yrrS S Protein of unknown function (DUF1510)
NHPPAGDG_03075 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NHPPAGDG_03076 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHPPAGDG_03077 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NHPPAGDG_03078 1.4e-245 yegQ O COG0826 Collagenase and related proteases
NHPPAGDG_03079 7.8e-174 yegQ O Peptidase U32
NHPPAGDG_03080 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
NHPPAGDG_03081 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHPPAGDG_03082 1.2e-45 yrzB S Belongs to the UPF0473 family
NHPPAGDG_03083 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHPPAGDG_03084 1.7e-41 yrzL S Belongs to the UPF0297 family
NHPPAGDG_03085 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHPPAGDG_03086 2.5e-168 yrrI S AI-2E family transporter
NHPPAGDG_03087 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NHPPAGDG_03088 2.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
NHPPAGDG_03089 2.3e-108 gluC P ABC transporter
NHPPAGDG_03090 7.6e-107 glnP P ABC transporter
NHPPAGDG_03091 8e-08 S Protein of unknown function (DUF3918)
NHPPAGDG_03092 9.8e-31 yrzR
NHPPAGDG_03093 6.6e-81 yrrD S protein conserved in bacteria
NHPPAGDG_03094 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHPPAGDG_03095 1.4e-15 S COG0457 FOG TPR repeat
NHPPAGDG_03096 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHPPAGDG_03097 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
NHPPAGDG_03098 1.2e-70 cymR K Transcriptional regulator
NHPPAGDG_03099 1.3e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NHPPAGDG_03100 1.1e-13 yoaF
NHPPAGDG_03101 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHPPAGDG_03102 3.1e-184 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPPAGDG_03103 3e-273 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NHPPAGDG_03104 6.2e-235 yoaB EGP Major facilitator Superfamily
NHPPAGDG_03105 3.9e-93 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHPPAGDG_03106 4.6e-124 yoxB
NHPPAGDG_03107 7.1e-39 yoxC S Bacterial protein of unknown function (DUF948)
NHPPAGDG_03108 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPPAGDG_03109 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NHPPAGDG_03110 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHPPAGDG_03111 7.8e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHPPAGDG_03112 7.8e-155 gltC K Transcriptional regulator
NHPPAGDG_03113 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NHPPAGDG_03114 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NHPPAGDG_03115 1.8e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NHPPAGDG_03116 8.8e-156 gltR1 K Transcriptional regulator
NHPPAGDG_03117 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NHPPAGDG_03118 8.7e-34 yoeD G Helix-turn-helix domain
NHPPAGDG_03119 2.2e-96 L Integrase
NHPPAGDG_03121 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NHPPAGDG_03122 2.3e-246 yoeA V MATE efflux family protein
NHPPAGDG_03123 6.9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
NHPPAGDG_03124 1.7e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NHPPAGDG_03125 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPPAGDG_03126 7.1e-262 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NHPPAGDG_03127 1e-154 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NHPPAGDG_03128 3.8e-221 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NHPPAGDG_03129 2.8e-64 yngL S Protein of unknown function (DUF1360)
NHPPAGDG_03130 8.5e-303 yngK T Glycosyl hydrolase-like 10
NHPPAGDG_03131 3.1e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NHPPAGDG_03132 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NHPPAGDG_03133 5.6e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NHPPAGDG_03134 7.3e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NHPPAGDG_03135 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NHPPAGDG_03136 1.7e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NHPPAGDG_03137 4.5e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHPPAGDG_03138 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
NHPPAGDG_03139 5.5e-104 yngC S membrane-associated protein
NHPPAGDG_03140 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHPPAGDG_03141 1.4e-75 yngA S membrane
NHPPAGDG_03142 6.2e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NHPPAGDG_03143 3.5e-76 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NHPPAGDG_03144 2.4e-155 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NHPPAGDG_03146 4.2e-294 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NHPPAGDG_03147 7.6e-250 agcS E Sodium alanine symporter
NHPPAGDG_03148 8.6e-57 ynfC
NHPPAGDG_03149 2.3e-12
NHPPAGDG_03150 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHPPAGDG_03151 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHPPAGDG_03152 6.6e-69 yccU S CoA-binding protein
NHPPAGDG_03153 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHPPAGDG_03154 4.1e-49 yneR S Belongs to the HesB IscA family
NHPPAGDG_03155 1.9e-52 yneQ
NHPPAGDG_03156 1.2e-73 yneP S Thioesterase-like superfamily
NHPPAGDG_03157 3.9e-35 tlp S Belongs to the Tlp family
NHPPAGDG_03158 3.1e-08 sspN S Small acid-soluble spore protein N family
NHPPAGDG_03160 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NHPPAGDG_03161 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NHPPAGDG_03162 2.2e-14 sspO S Belongs to the SspO family
NHPPAGDG_03163 3.9e-19 sspP S Belongs to the SspP family
NHPPAGDG_03164 5.9e-64 hspX O Spore coat protein
NHPPAGDG_03165 1.2e-73 yneK S Protein of unknown function (DUF2621)
NHPPAGDG_03166 1.6e-76 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NHPPAGDG_03167 6.3e-60 ybbJ J acetyltransferase
NHPPAGDG_03168 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NHPPAGDG_03169 7.4e-147 ybbH K transcriptional
NHPPAGDG_03170 1.3e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPPAGDG_03171 7e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NHPPAGDG_03172 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NHPPAGDG_03173 1.6e-235 ybbC 3.2.1.52 S protein conserved in bacteria
NHPPAGDG_03174 1.4e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NHPPAGDG_03175 8.3e-163 feuA P Iron-uptake system-binding protein
NHPPAGDG_03176 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_03177 8.7e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_03178 1.4e-141 ybbA S Putative esterase
NHPPAGDG_03179 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
NHPPAGDG_03180 1.8e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NHPPAGDG_03182 3.3e-113 tetR3 K Transcriptional regulator
NHPPAGDG_03183 1.9e-118 mepA V Multidrug transporter MatE
NHPPAGDG_03184 5.3e-70 mepA V Multidrug transporter MatE
NHPPAGDG_03185 6e-165 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NHPPAGDG_03186 2.1e-111 yrkJ S membrane transporter protein
NHPPAGDG_03187 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
NHPPAGDG_03188 9.3e-206 yrkH P Rhodanese Homology Domain
NHPPAGDG_03189 4.7e-16 perX S Sulfur reduction protein DsrE
NHPPAGDG_03190 4.2e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
NHPPAGDG_03191 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
NHPPAGDG_03192 7.8e-39 yrkD S protein conserved in bacteria
NHPPAGDG_03193 8.6e-21
NHPPAGDG_03194 1.8e-104 yrkC G Cupin domain
NHPPAGDG_03195 3.1e-150 bltR K helix_turn_helix, mercury resistance
NHPPAGDG_03196 3.5e-211 blt EGP Major facilitator Superfamily
NHPPAGDG_03197 1.5e-82 bltD 2.3.1.57 K FR47-like protein
NHPPAGDG_03198 1.1e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NHPPAGDG_03199 3.9e-16 S YrzO-like protein
NHPPAGDG_03200 1.9e-170 yrdR EG EamA-like transporter family
NHPPAGDG_03201 6.6e-159 yrdQ K Transcriptional regulator
NHPPAGDG_03202 3.6e-196 trkA P Oxidoreductase
NHPPAGDG_03203 2.6e-153 czcD P COG1230 Co Zn Cd efflux system component
NHPPAGDG_03204 4.2e-65 yodA S tautomerase
NHPPAGDG_03205 5e-162 gltR K LysR substrate binding domain
NHPPAGDG_03206 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
NHPPAGDG_03207 5.6e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NHPPAGDG_03208 2.2e-91 azlC E AzlC protein
NHPPAGDG_03209 1.1e-78 bkdR K helix_turn_helix ASNC type
NHPPAGDG_03210 2.6e-40 yrdF K ribonuclease inhibitor
NHPPAGDG_03211 2.1e-227 cypA C Cytochrome P450
NHPPAGDG_03212 4.2e-23 K Acetyltransferase (GNAT) family
NHPPAGDG_03213 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
NHPPAGDG_03214 1.9e-57 S Protein of unknown function (DUF2568)
NHPPAGDG_03216 6.4e-90 yrdA S DinB family
NHPPAGDG_03217 5.9e-171 L COG3666 Transposase and inactivated derivatives
NHPPAGDG_03218 1.1e-23 cat P Catalase
NHPPAGDG_03219 2.1e-91 cat P Catalase
NHPPAGDG_03220 1.4e-107 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NHPPAGDG_03221 2.2e-80 yokK S SMI1 / KNR4 family
NHPPAGDG_03222 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
NHPPAGDG_03223 3.8e-291 UW nuclease activity
NHPPAGDG_03224 1.1e-101 yokH G SMI1 / KNR4 family
NHPPAGDG_03225 1.1e-275 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NHPPAGDG_03226 1e-198 yobO M Pectate lyase superfamily protein
NHPPAGDG_03227 6.9e-221 yobO M Pectate lyase superfamily protein
NHPPAGDG_03228 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NHPPAGDG_03229 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
NHPPAGDG_03230 1.2e-140 yobR 2.3.1.1 J FR47-like protein
NHPPAGDG_03231 1.3e-97 yobS K Transcriptional regulator
NHPPAGDG_03232 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NHPPAGDG_03233 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
NHPPAGDG_03234 2.7e-174 yobV K WYL domain
NHPPAGDG_03235 2.6e-92 yobW
NHPPAGDG_03236 1e-51 czrA K transcriptional
NHPPAGDG_03237 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NHPPAGDG_03238 1.5e-92 yozB S membrane
NHPPAGDG_03239 5.1e-142
NHPPAGDG_03240 1.5e-91 yocC
NHPPAGDG_03241 6e-185 yocD 3.4.17.13 V peptidase S66
NHPPAGDG_03242 1.2e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NHPPAGDG_03243 7.1e-198 desK 2.7.13.3 T Histidine kinase
NHPPAGDG_03244 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPPAGDG_03245 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NHPPAGDG_03246 0.0 recQ 3.6.4.12 L DNA helicase
NHPPAGDG_03247 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHPPAGDG_03248 3.3e-83 dksA T general stress protein
NHPPAGDG_03249 3.2e-53 yocL
NHPPAGDG_03250 1.4e-31
NHPPAGDG_03251 7e-86 yocM O Belongs to the small heat shock protein (HSP20) family
NHPPAGDG_03252 1.1e-40 yozN
NHPPAGDG_03253 1.9e-36 yocN
NHPPAGDG_03254 4.2e-56 yozO S Bacterial PH domain
NHPPAGDG_03255 2.7e-31 yozC
NHPPAGDG_03256 2e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NHPPAGDG_03257 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NHPPAGDG_03258 6e-165 sodA 1.15.1.1 P Superoxide dismutase
NHPPAGDG_03259 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NHPPAGDG_03260 6.2e-166 yocS S -transporter
NHPPAGDG_03261 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NHPPAGDG_03262 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NHPPAGDG_03263 0.0 yojO P Von Willebrand factor
NHPPAGDG_03264 2.5e-161 yojN S ATPase family associated with various cellular activities (AAA)
NHPPAGDG_03265 5.6e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NHPPAGDG_03266 9.6e-196 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NHPPAGDG_03267 1e-229 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NHPPAGDG_03268 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHPPAGDG_03270 2.2e-241 norM V Multidrug efflux pump
NHPPAGDG_03271 1.6e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHPPAGDG_03272 2.1e-125 yojG S deacetylase
NHPPAGDG_03273 2.2e-60 yojF S Protein of unknown function (DUF1806)
NHPPAGDG_03274 1.5e-43
NHPPAGDG_03275 6.6e-162 rarD S -transporter
NHPPAGDG_03276 4.3e-64 yozR S COG0071 Molecular chaperone (small heat shock protein)
NHPPAGDG_03277 2e-09
NHPPAGDG_03278 1.2e-204 gntP EG COG2610 H gluconate symporter and related permeases
NHPPAGDG_03279 1.5e-62 yodA S tautomerase
NHPPAGDG_03280 4.4e-55 yodB K transcriptional
NHPPAGDG_03281 4.8e-108 yodC C nitroreductase
NHPPAGDG_03282 1.7e-20 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NHPPAGDG_03283 2.8e-179 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NHPPAGDG_03284 9.3e-48 S SMI1-KNR4 cell-wall
NHPPAGDG_03286 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
NHPPAGDG_03294 0.0 yhgF K COG2183 Transcriptional accessory protein
NHPPAGDG_03295 1.4e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NHPPAGDG_03296 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPPAGDG_03297 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NHPPAGDG_03298 3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
NHPPAGDG_03299 7.1e-189 rsbU 3.1.3.3 KT phosphatase
NHPPAGDG_03300 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NHPPAGDG_03301 5.2e-57 rsbS T antagonist
NHPPAGDG_03302 1.3e-143 rsbR T Positive regulator of sigma-B
NHPPAGDG_03303 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NHPPAGDG_03304 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NHPPAGDG_03305 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHPPAGDG_03306 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NHPPAGDG_03307 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHPPAGDG_03308 6.9e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NHPPAGDG_03309 8.6e-260 ydbT S Membrane
NHPPAGDG_03310 2.1e-82 ydbS S Bacterial PH domain
NHPPAGDG_03311 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHPPAGDG_03312 5.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHPPAGDG_03313 5.6e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NHPPAGDG_03314 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NHPPAGDG_03315 4.8e-149 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHPPAGDG_03316 2.2e-07 S Fur-regulated basic protein A
NHPPAGDG_03317 1.1e-18 S Fur-regulated basic protein B
NHPPAGDG_03318 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NHPPAGDG_03319 2.7e-52 ydbL
NHPPAGDG_03320 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHPPAGDG_03321 1.3e-168 ydbJ V ABC transporter, ATP-binding protein
NHPPAGDG_03322 2.8e-180 ydbI S AI-2E family transporter
NHPPAGDG_03323 3.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHPPAGDG_03324 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
NHPPAGDG_03325 1.5e-294 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NHPPAGDG_03326 1.1e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NHPPAGDG_03327 1.2e-138 ydbD P Catalase
NHPPAGDG_03328 2.6e-61 ydbC S Domain of unknown function (DUF4937
NHPPAGDG_03329 2.6e-58 ydbB G Cupin domain
NHPPAGDG_03331 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NHPPAGDG_03332 3.7e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NHPPAGDG_03334 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NHPPAGDG_03335 3.6e-39
NHPPAGDG_03336 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NHPPAGDG_03337 5.2e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NHPPAGDG_03338 0.0 ydaO E amino acid
NHPPAGDG_03339 2.4e-99 ydaN S Bacterial cellulose synthase subunit
NHPPAGDG_03340 5.5e-67 ydaN S Bacterial cellulose synthase subunit
NHPPAGDG_03341 1e-185 ydaN S Bacterial cellulose synthase subunit
NHPPAGDG_03342 5.9e-233 ydaM M Glycosyl transferase family group 2
NHPPAGDG_03343 1e-176 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NHPPAGDG_03344 5e-132 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NHPPAGDG_03345 3.9e-30 ydaK T Diguanylate cyclase, GGDEF domain
NHPPAGDG_03346 1.2e-89 ydaK T Diguanylate cyclase, GGDEF domain
NHPPAGDG_03347 1.2e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NHPPAGDG_03348 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHPPAGDG_03349 2.5e-74 lrpC K Transcriptional regulator
NHPPAGDG_03350 1.1e-44 ydzA EGP Major facilitator Superfamily
NHPPAGDG_03351 4.6e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NHPPAGDG_03352 6.4e-75 ydaG 1.4.3.5 S general stress protein
NHPPAGDG_03353 8e-102 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHPPAGDG_03354 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NHPPAGDG_03355 7e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPPAGDG_03356 2e-98 ydaC Q Methyltransferase domain
NHPPAGDG_03357 1.8e-292 ydaB IQ acyl-CoA ligase
NHPPAGDG_03358 0.0 mtlR K transcriptional regulator, MtlR
NHPPAGDG_03359 9.2e-172 ydhF S Oxidoreductase
NHPPAGDG_03360 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NHPPAGDG_03362 6.9e-32 yczJ S biosynthesis
NHPPAGDG_03364 4.9e-119 ycsK E anatomical structure formation involved in morphogenesis
NHPPAGDG_03365 3.9e-131 kipR K Transcriptional regulator
NHPPAGDG_03366 6.9e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NHPPAGDG_03367 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NHPPAGDG_03368 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
NHPPAGDG_03369 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NHPPAGDG_03370 3.6e-140 ycsF S Belongs to the UPF0271 (lamB) family
NHPPAGDG_03371 5.2e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NHPPAGDG_03373 5e-76
NHPPAGDG_03374 8.6e-119 L COG2801 Transposase and inactivated derivatives
NHPPAGDG_03375 9.1e-50 L Transposase
NHPPAGDG_03376 1.5e-38 EG Spore germination protein
NHPPAGDG_03377 1.2e-13 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPPAGDG_03378 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
NHPPAGDG_03379 5.1e-210 yttB EGP Major facilitator Superfamily
NHPPAGDG_03380 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NHPPAGDG_03381 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NHPPAGDG_03382 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHPPAGDG_03383 2.1e-51 ytwF P Sulfurtransferase
NHPPAGDG_03384 1.2e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NHPPAGDG_03385 5.7e-144 amyC P ABC transporter (permease)
NHPPAGDG_03386 6.2e-168 amyD P ABC transporter
NHPPAGDG_03387 1.4e-245 msmE G Bacterial extracellular solute-binding protein
NHPPAGDG_03388 1.5e-189 msmR K Transcriptional regulator
NHPPAGDG_03389 3.2e-172 ytaP S Acetyl xylan esterase (AXE1)
NHPPAGDG_03390 5.5e-149 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NHPPAGDG_03391 1.5e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NHPPAGDG_03392 3.7e-213 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NHPPAGDG_03393 2.3e-122 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NHPPAGDG_03394 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NHPPAGDG_03395 1.8e-223 bioI 1.14.14.46 C Cytochrome P450
NHPPAGDG_03396 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NHPPAGDG_03397 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
NHPPAGDG_03398 2.7e-285 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NHPPAGDG_03399 0.0 ytdP K Transcriptional regulator
NHPPAGDG_03400 2.2e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NHPPAGDG_03401 6.6e-220 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NHPPAGDG_03402 2.1e-70 yteS G transport
NHPPAGDG_03403 7.3e-255 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NHPPAGDG_03404 8.5e-114 yteU S Integral membrane protein
NHPPAGDG_03405 3.1e-26 yteV S Sporulation protein Cse60
NHPPAGDG_03406 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NHPPAGDG_03407 9e-231 ytfP S HI0933-like protein
NHPPAGDG_03408 2.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPPAGDG_03409 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHPPAGDG_03410 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NHPPAGDG_03411 4.8e-131 ythP V ABC transporter
NHPPAGDG_03412 1.7e-202 ythQ U Bacterial ABC transporter protein EcsB
NHPPAGDG_03413 2.1e-225 pbuO S permease
NHPPAGDG_03414 1.5e-269 pepV 3.5.1.18 E Dipeptidase
NHPPAGDG_03415 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NHPPAGDG_03416 3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NHPPAGDG_03417 2.2e-165 ytlQ
NHPPAGDG_03418 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NHPPAGDG_03419 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NHPPAGDG_03420 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NHPPAGDG_03421 2e-45 ytzH S YtzH-like protein
NHPPAGDG_03422 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHPPAGDG_03423 3.9e-148 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NHPPAGDG_03424 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NHPPAGDG_03425 2.2e-51 ytzB S small secreted protein
NHPPAGDG_03426 1.3e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NHPPAGDG_03427 3.5e-21 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NHPPAGDG_03428 6.7e-48 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NHPPAGDG_03429 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NHPPAGDG_03430 4.8e-148 ytpQ S Belongs to the UPF0354 family
NHPPAGDG_03431 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHPPAGDG_03432 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NHPPAGDG_03433 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NHPPAGDG_03434 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHPPAGDG_03435 6.6e-17 ytxH S COG4980 Gas vesicle protein
NHPPAGDG_03436 2.4e-53 ytxJ O Protein of unknown function (DUF2847)
NHPPAGDG_03437 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NHPPAGDG_03438 3.8e-182 ccpA K catabolite control protein A
NHPPAGDG_03439 2.1e-146 motA N flagellar motor
NHPPAGDG_03440 5.2e-125 motS N Flagellar motor protein
NHPPAGDG_03441 5.4e-225 acuC BQ histone deacetylase
NHPPAGDG_03442 3.5e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NHPPAGDG_03443 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NHPPAGDG_03444 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NHPPAGDG_03445 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHPPAGDG_03447 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHPPAGDG_03448 2.5e-306 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NHPPAGDG_03449 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
NHPPAGDG_03450 4.1e-142 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHPPAGDG_03451 4.5e-24 yqzJ
NHPPAGDG_03452 3.4e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHPPAGDG_03453 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHPPAGDG_03454 1.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NHPPAGDG_03455 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHPPAGDG_03456 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHPPAGDG_03457 5e-86 thiT S Thiamine transporter protein (Thia_YuaJ)
NHPPAGDG_03458 3.4e-94 M1-753 M FR47-like protein
NHPPAGDG_03459 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
NHPPAGDG_03460 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NHPPAGDG_03461 3.9e-84 yuaE S DinB superfamily
NHPPAGDG_03462 7.4e-106 yuaD
NHPPAGDG_03463 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
NHPPAGDG_03464 1.2e-280 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NHPPAGDG_03465 5.5e-95 yuaC K Belongs to the GbsR family
NHPPAGDG_03466 2.2e-91 yuaB
NHPPAGDG_03467 6.7e-167 ygxA S Nucleotidyltransferase-like
NHPPAGDG_03468 9.5e-56 ygzB S UPF0295 protein
NHPPAGDG_03469 4e-80 perR P Belongs to the Fur family
NHPPAGDG_03470 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
NHPPAGDG_03471 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NHPPAGDG_03472 5.6e-179 ygaE S Membrane
NHPPAGDG_03473 1.8e-301 ygaD V ABC transporter
NHPPAGDG_03474 2.8e-104 ygaC J Belongs to the UPF0374 family
NHPPAGDG_03475 4.9e-48 ygaB S YgaB-like protein
NHPPAGDG_03476 5.3e-08 sspE S Small, acid-soluble spore protein, gamma-type
NHPPAGDG_03477 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPPAGDG_03478 6.9e-36 yfhS
NHPPAGDG_03479 8.6e-211 mutY L A G-specific
NHPPAGDG_03480 6.1e-185 yfhP S membrane-bound metal-dependent
NHPPAGDG_03481 0.0 yfhO S Bacterial membrane protein YfhO
NHPPAGDG_03482 8.1e-182 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPPAGDG_03483 1.1e-169 yfhM S Alpha beta hydrolase
NHPPAGDG_03484 1e-47 yfhL S SdpI/YhfL protein family
NHPPAGDG_03485 1.3e-85 batE T Bacterial SH3 domain homologues
NHPPAGDG_03486 5.1e-72 ywnJ S VanZ like family
NHPPAGDG_03487 6.5e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NHPPAGDG_03488 1.6e-58 nrgB K Belongs to the P(II) protein family
NHPPAGDG_03489 7.4e-225 amt P Ammonium transporter
NHPPAGDG_03490 2.2e-76
NHPPAGDG_03491 8.9e-104 phzA Q Isochorismatase family
NHPPAGDG_03492 2.7e-239 ywoD EGP Major facilitator superfamily
NHPPAGDG_03493 3.5e-263 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NHPPAGDG_03494 2e-57 ywoF P Right handed beta helix region
NHPPAGDG_03495 8.1e-130 ywoF P Right handed beta helix region
NHPPAGDG_03496 2.7e-211 ywoG EGP Major facilitator Superfamily
NHPPAGDG_03497 2.1e-70 ywoH K COG1846 Transcriptional regulators
NHPPAGDG_03498 3e-44 spoIIID K Stage III sporulation protein D
NHPPAGDG_03499 3.5e-180 mbl D Rod shape-determining protein
NHPPAGDG_03500 6.9e-126 flhO N flagellar basal body
NHPPAGDG_03501 2.6e-141 flhP N flagellar basal body
NHPPAGDG_03502 4.8e-196 S aspartate phosphatase
NHPPAGDG_03503 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHPPAGDG_03504 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHPPAGDG_03505 2.4e-153 ywpD T Histidine kinase
NHPPAGDG_03506 2e-49 srtA 3.4.22.70 M Sortase family
NHPPAGDG_03507 2.4e-66 ywpF S YwpF-like protein
NHPPAGDG_03508 3.8e-66 ywpG
NHPPAGDG_03509 3.7e-57 ssbB L Single-stranded DNA-binding protein
NHPPAGDG_03510 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NHPPAGDG_03511 3.9e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NHPPAGDG_03512 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NHPPAGDG_03513 7.8e-307 ywqB S SWIM zinc finger
NHPPAGDG_03514 1.2e-17
NHPPAGDG_03515 5.9e-116 ywqC M biosynthesis protein
NHPPAGDG_03516 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NHPPAGDG_03517 1.1e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NHPPAGDG_03518 4.9e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHPPAGDG_03519 3.3e-30 ywqG S Domain of unknown function (DUF1963)
NHPPAGDG_03520 5.7e-85 ywqG S Domain of unknown function (DUF1963)
NHPPAGDG_03521 1e-19 S Domain of unknown function (DUF5082)
NHPPAGDG_03522 6.9e-38 ywqI S Family of unknown function (DUF5344)
NHPPAGDG_03523 1.6e-242 ywqJ S Pre-toxin TG
NHPPAGDG_03524 3.9e-25
NHPPAGDG_03525 3.9e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NHPPAGDG_03526 1.4e-161 K Transcriptional regulator
NHPPAGDG_03527 3.3e-100 ywqN S NAD(P)H-dependent
NHPPAGDG_03529 1.7e-88 ywrA P COG2059 Chromate transport protein ChrA
NHPPAGDG_03530 7.8e-103 ywrB P Chromate transporter
NHPPAGDG_03531 8e-82 ywrC K Transcriptional regulator
NHPPAGDG_03532 1.8e-300 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NHPPAGDG_03533 2.7e-52 S Domain of unknown function (DUF4181)
NHPPAGDG_03534 9.9e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHPPAGDG_03535 1.1e-12
NHPPAGDG_03536 2.4e-206 cotH M Spore Coat
NHPPAGDG_03537 1.4e-23 cotB
NHPPAGDG_03538 8.8e-77 cotB
NHPPAGDG_03539 1.4e-124 ywrJ
NHPPAGDG_03540 6.2e-155 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NHPPAGDG_03541 1.1e-169 alsR K LysR substrate binding domain
NHPPAGDG_03542 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NHPPAGDG_03543 4.1e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NHPPAGDG_03544 3.3e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NHPPAGDG_03545 8e-48 ywsA S Protein of unknown function (DUF3892)
NHPPAGDG_03546 1.2e-91 batE T Sh3 type 3 domain protein
NHPPAGDG_03547 3.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NHPPAGDG_03548 9.3e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NHPPAGDG_03549 4e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NHPPAGDG_03550 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NHPPAGDG_03551 8.4e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHPPAGDG_03552 5.5e-178 rbsR K transcriptional
NHPPAGDG_03553 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NHPPAGDG_03554 8.6e-70 pgsC S biosynthesis protein
NHPPAGDG_03555 1.8e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NHPPAGDG_03556 3.6e-21 ywtC
NHPPAGDG_03557 4.9e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NHPPAGDG_03558 3.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NHPPAGDG_03559 4.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NHPPAGDG_03560 1e-164 aadK G Streptomycin adenylyltransferase
NHPPAGDG_03561 2.5e-11 tnpIS3 L Transposase
NHPPAGDG_03562 1e-154 yitG EGP Major facilitator Superfamily
NHPPAGDG_03563 1.8e-156 yitH K Acetyltransferase (GNAT) domain
NHPPAGDG_03564 1e-70 yjcF S Acetyltransferase (GNAT) domain
NHPPAGDG_03565 1.2e-129 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NHPPAGDG_03566 8.6e-55 yajQ S Belongs to the UPF0234 family
NHPPAGDG_03567 1.3e-159 cvfB S protein conserved in bacteria
NHPPAGDG_03568 1.3e-58
NHPPAGDG_03569 4.1e-87
NHPPAGDG_03570 1.5e-97 S Sporulation delaying protein SdpA
NHPPAGDG_03571 1.5e-58 K Transcriptional regulator PadR-like family
NHPPAGDG_03572 1.6e-92
NHPPAGDG_03573 1.4e-44 yitR S Domain of unknown function (DUF3784)
NHPPAGDG_03574 3.2e-308 nprB 3.4.24.28 E Peptidase M4
NHPPAGDG_03575 9.3e-158 yitS S protein conserved in bacteria
NHPPAGDG_03576 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NHPPAGDG_03577 1.4e-72 ipi S Intracellular proteinase inhibitor
NHPPAGDG_03578 1.2e-17 S Protein of unknown function (DUF3813)
NHPPAGDG_03580 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NHPPAGDG_03581 1.1e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NHPPAGDG_03582 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NHPPAGDG_03583 1.5e-22 pilT S Proteolipid membrane potential modulator
NHPPAGDG_03584 9.2e-267 yitY C D-arabinono-1,4-lactone oxidase
NHPPAGDG_03585 4.9e-88 norB G Major Facilitator Superfamily
NHPPAGDG_03586 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NHPPAGDG_03587 1e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHPPAGDG_03588 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NHPPAGDG_03589 2.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NHPPAGDG_03590 1.1e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NHPPAGDG_03591 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NHPPAGDG_03592 2.8e-174 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHPPAGDG_03593 9.5e-28 yjzC S YjzC-like protein
NHPPAGDG_03594 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NHPPAGDG_03595 6.8e-141 yjaU I carboxylic ester hydrolase activity
NHPPAGDG_03596 1.7e-99 yjaV
NHPPAGDG_03597 4.2e-183 med S Transcriptional activator protein med
NHPPAGDG_03598 7.3e-26 comZ S ComZ
NHPPAGDG_03599 2.7e-22 yjzB
NHPPAGDG_03600 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHPPAGDG_03601 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHPPAGDG_03602 3.3e-149 yjaZ O Zn-dependent protease
NHPPAGDG_03603 1.8e-184 appD P Belongs to the ABC transporter superfamily
NHPPAGDG_03604 2.7e-185 appF E Belongs to the ABC transporter superfamily
NHPPAGDG_03605 1.4e-279 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NHPPAGDG_03606 1.9e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPPAGDG_03607 1.8e-154 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPPAGDG_03608 1.9e-146 yjbA S Belongs to the UPF0736 family
NHPPAGDG_03609 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NHPPAGDG_03610 8.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NHPPAGDG_03611 1.2e-73 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NHPPAGDG_03612 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NHPPAGDG_03613 1.1e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NHPPAGDG_03614 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NHPPAGDG_03615 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NHPPAGDG_03616 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NHPPAGDG_03617 7.3e-56
NHPPAGDG_03618 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NHPPAGDG_03619 9.7e-305 ycnJ P protein, homolog of Cu resistance protein CopC
NHPPAGDG_03620 6.6e-97 ycnI S protein conserved in bacteria
NHPPAGDG_03621 1.4e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPPAGDG_03622 6.1e-149 glcU U Glucose uptake
NHPPAGDG_03623 1.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHPPAGDG_03624 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHPPAGDG_03625 4e-270 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPPAGDG_03626 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NHPPAGDG_03627 1.6e-45 ycnE S Monooxygenase
NHPPAGDG_03628 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NHPPAGDG_03629 5.5e-153 ycnC K Transcriptional regulator
NHPPAGDG_03630 4.1e-251 ycnB EGP Major facilitator Superfamily
NHPPAGDG_03631 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NHPPAGDG_03632 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NHPPAGDG_03633 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_03634 1e-160 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_03635 2.8e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
NHPPAGDG_03639 1.4e-71 S aspartate phosphatase
NHPPAGDG_03640 1.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NHPPAGDG_03641 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPPAGDG_03642 4.8e-202 yclI V ABC transporter (permease) YclI
NHPPAGDG_03643 7.3e-121 yclH P ABC transporter
NHPPAGDG_03644 1.3e-194 gerKB F Spore germination protein
NHPPAGDG_03645 4e-226 gerKC S spore germination
NHPPAGDG_03646 7.8e-278 gerKA EG Spore germination protein
NHPPAGDG_03648 4.6e-292 yclG M Pectate lyase superfamily protein
NHPPAGDG_03649 9.2e-262 dtpT E amino acid peptide transporter
NHPPAGDG_03650 6e-157 yclE 3.4.11.5 S Alpha beta hydrolase
NHPPAGDG_03651 1.6e-39 yclD
NHPPAGDG_03652 3.4e-38 bsdD 4.1.1.61 S response to toxic substance
NHPPAGDG_03653 4.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NHPPAGDG_03654 5.4e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NHPPAGDG_03655 1.9e-161 bsdA K LysR substrate binding domain
NHPPAGDG_03656 4.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NHPPAGDG_03657 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NHPPAGDG_03658 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NHPPAGDG_03659 9.7e-115 yczE S membrane
NHPPAGDG_03660 9.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NHPPAGDG_03661 1.8e-248 ycxD K GntR family transcriptional regulator
NHPPAGDG_03662 5.8e-161 ycxC EG EamA-like transporter family
NHPPAGDG_03663 1.1e-07 S YcxB-like protein
NHPPAGDG_03664 1.3e-38 S YcxB-like protein
NHPPAGDG_03665 2.3e-102 EGP Major Facilitator Superfamily
NHPPAGDG_03666 2.2e-139 srfAD Q thioesterase
NHPPAGDG_03667 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NHPPAGDG_03668 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPPAGDG_03669 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPPAGDG_03670 6.3e-63 hxlR K transcriptional
NHPPAGDG_03671 4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NHPPAGDG_03672 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NHPPAGDG_03673 1.4e-176 tlpC 2.7.13.3 NT chemotaxis protein
NHPPAGDG_03674 5.6e-69 nucA M Deoxyribonuclease NucA/NucB
NHPPAGDG_03675 8.5e-69 nin S Competence protein J (ComJ)
NHPPAGDG_03676 1.2e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHPPAGDG_03677 7.8e-52 yckD S Protein of unknown function (DUF2680)
NHPPAGDG_03678 3.7e-42 yckC S membrane
NHPPAGDG_03680 1.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHPPAGDG_03681 1e-114 yecS P COG0765 ABC-type amino acid transport system, permease component
NHPPAGDG_03682 1.8e-98 yciC S GTPases (G3E family)
NHPPAGDG_03683 3.6e-112 yciC S GTPases (G3E family)
NHPPAGDG_03684 4.2e-101 yciB M ErfK YbiS YcfS YnhG
NHPPAGDG_03685 1.2e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NHPPAGDG_03686 1.7e-221 nasA P COG2223 Nitrate nitrite transporter
NHPPAGDG_03687 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NHPPAGDG_03688 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHPPAGDG_03689 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHPPAGDG_03690 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NHPPAGDG_03691 8.7e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NHPPAGDG_03692 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NHPPAGDG_03693 1.6e-157 I alpha/beta hydrolase fold
NHPPAGDG_03694 1.2e-139 ycgR S permeases
NHPPAGDG_03695 4.8e-146 ycgQ S membrane
NHPPAGDG_03696 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NHPPAGDG_03697 8e-74 cueR K transcriptional
NHPPAGDG_03698 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
NHPPAGDG_03699 3e-210 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NHPPAGDG_03700 1.1e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHPPAGDG_03701 6.2e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHPPAGDG_03702 6.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NHPPAGDG_03704 5.6e-203 yhdY M Mechanosensitive ion channel
NHPPAGDG_03705 2.6e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NHPPAGDG_03706 3.9e-148 yheN G deacetylase
NHPPAGDG_03707 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NHPPAGDG_03708 1.2e-231 nhaC C Na H antiporter
NHPPAGDG_03709 3.4e-84 nhaX T Belongs to the universal stress protein A family
NHPPAGDG_03710 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NHPPAGDG_03711 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NHPPAGDG_03712 6.5e-108 yheG GM NAD(P)H-binding
NHPPAGDG_03713 6.3e-28 sspB S spore protein
NHPPAGDG_03714 1.3e-36 yheE S Family of unknown function (DUF5342)
NHPPAGDG_03715 2.8e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NHPPAGDG_03716 4.8e-215 yheC HJ YheC/D like ATP-grasp
NHPPAGDG_03717 4.1e-201 yheB S Belongs to the UPF0754 family
NHPPAGDG_03718 9.5e-48 yheA S Belongs to the UPF0342 family
NHPPAGDG_03719 1.3e-204 yhaZ L DNA alkylation repair enzyme
NHPPAGDG_03720 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NHPPAGDG_03721 1e-292 hemZ H coproporphyrinogen III oxidase
NHPPAGDG_03722 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NHPPAGDG_03723 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NHPPAGDG_03725 6.4e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
NHPPAGDG_03726 3.2e-26 S YhzD-like protein
NHPPAGDG_03727 4e-167 yhaQ S ABC transporter, ATP-binding protein
NHPPAGDG_03728 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NHPPAGDG_03729 1.3e-224 yhaO L DNA repair exonuclease
NHPPAGDG_03730 0.0 yhaN L AAA domain
NHPPAGDG_03731 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NHPPAGDG_03732 1.6e-21 yhaL S Sporulation protein YhaL
NHPPAGDG_03733 1.8e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NHPPAGDG_03734 8.7e-90 yhaK S Putative zincin peptidase
NHPPAGDG_03735 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NHPPAGDG_03736 1e-113 hpr K Negative regulator of protease production and sporulation
NHPPAGDG_03737 7.1e-39 yhaH S YtxH-like protein
NHPPAGDG_03738 8.1e-80 trpP S Tryptophan transporter TrpP
NHPPAGDG_03739 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NHPPAGDG_03740 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NHPPAGDG_03741 4.6e-137 ecsA V transporter (ATP-binding protein)
NHPPAGDG_03742 1.6e-214 ecsB U ABC transporter
NHPPAGDG_03743 1.4e-114 ecsC S EcsC protein family
NHPPAGDG_03744 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHPPAGDG_03745 1.9e-245 yhfA C membrane
NHPPAGDG_03746 1.9e-34 1.15.1.2 C Rubrerythrin
NHPPAGDG_03747 9.2e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NHPPAGDG_03748 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NHPPAGDG_03749 4.5e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NHPPAGDG_03750 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NHPPAGDG_03751 1.2e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NHPPAGDG_03752 4.6e-100 yhgD K Transcriptional regulator
NHPPAGDG_03753 8.6e-214 yhgE S YhgE Pip N-terminal domain protein
NHPPAGDG_03754 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHPPAGDG_03755 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
NHPPAGDG_03756 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NHPPAGDG_03757 3.7e-72 3.4.13.21 S ASCH
NHPPAGDG_03758 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHPPAGDG_03759 3.4e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NHPPAGDG_03760 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NHPPAGDG_03761 2.9e-111 yhfK GM NmrA-like family
NHPPAGDG_03762 3.1e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NHPPAGDG_03763 1.9e-65 yhfM
NHPPAGDG_03764 2.5e-239 yhfN 3.4.24.84 O Peptidase M48
NHPPAGDG_03765 1.2e-203 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NHPPAGDG_03766 6.2e-76 VY92_01935 K acetyltransferase
NHPPAGDG_03767 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
NHPPAGDG_03768 1.1e-154 yfmC M Periplasmic binding protein
NHPPAGDG_03769 7.1e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NHPPAGDG_03770 6.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
NHPPAGDG_03771 1.8e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NHPPAGDG_03772 5e-91 bioY S BioY family
NHPPAGDG_03773 9.2e-181 hemAT NT chemotaxis protein
NHPPAGDG_03774 7.4e-97 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NHPPAGDG_03775 2.3e-184 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NHPPAGDG_03776 1.5e-155 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPPAGDG_03777 1.3e-32 yhzC S IDEAL
NHPPAGDG_03778 4.2e-109 comK K Competence transcription factor
NHPPAGDG_03779 3.9e-162 IQ Enoyl-(Acyl carrier protein) reductase
NHPPAGDG_03780 1.1e-40 yhjA S Excalibur calcium-binding domain
NHPPAGDG_03781 2.3e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPPAGDG_03782 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NHPPAGDG_03783 6.7e-60 yhjD
NHPPAGDG_03784 9.1e-110 yhjE S SNARE associated Golgi protein
NHPPAGDG_03785 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NHPPAGDG_03786 1.6e-282 yhjG CH FAD binding domain
NHPPAGDG_03787 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NHPPAGDG_03788 3.4e-214 glcP G Major Facilitator Superfamily
NHPPAGDG_03789 4.6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NHPPAGDG_03790 9e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NHPPAGDG_03791 5.9e-79 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NHPPAGDG_03792 5.4e-116 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NHPPAGDG_03793 1.7e-187 yhjM 5.1.1.1 K Transcriptional regulator
NHPPAGDG_03794 1.9e-201 abrB S membrane
NHPPAGDG_03795 2.2e-213 EGP Transmembrane secretion effector
NHPPAGDG_03796 0.0 S Sugar transport-related sRNA regulator N-term
NHPPAGDG_03797 2.2e-78 yhjR S Rubrerythrin
NHPPAGDG_03798 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NHPPAGDG_03799 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NHPPAGDG_03800 1.6e-100 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHPPAGDG_03801 0.0 sbcC L COG0419 ATPase involved in DNA repair
NHPPAGDG_03802 3.1e-47 yisB V COG1403 Restriction endonuclease
NHPPAGDG_03803 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NHPPAGDG_03804 3e-66 gerPE S Spore germination protein GerPE
NHPPAGDG_03805 6.3e-24 gerPD S Spore germination protein
NHPPAGDG_03806 5.3e-54 gerPC S Spore germination protein
NHPPAGDG_03807 4e-34 gerPB S cell differentiation
NHPPAGDG_03808 1.9e-33 gerPA S Spore germination protein
NHPPAGDG_03809 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NHPPAGDG_03810 8.5e-173 cotH M Spore Coat
NHPPAGDG_03811 2.1e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NHPPAGDG_03812 1.9e-56 yisL S UPF0344 protein
NHPPAGDG_03813 0.0 wprA O Belongs to the peptidase S8 family
NHPPAGDG_03814 2.8e-102 yisN S Protein of unknown function (DUF2777)
NHPPAGDG_03815 0.0 asnO 6.3.5.4 E Asparagine synthase
NHPPAGDG_03816 8.9e-118 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NHPPAGDG_03817 1.5e-242 yisQ V Mate efflux family protein
NHPPAGDG_03818 3.5e-160 yisR K Transcriptional regulator
NHPPAGDG_03819 5.2e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NHPPAGDG_03820 7e-92 yisT S DinB family
NHPPAGDG_03821 1.2e-106 argO S Lysine exporter protein LysE YggA
NHPPAGDG_03822 7.6e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPPAGDG_03823 2e-35 mcbG S Pentapeptide repeats (9 copies)
NHPPAGDG_03824 4.2e-152 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHPPAGDG_03825 6e-111 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NHPPAGDG_03826 5.1e-164 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NHPPAGDG_03827 5.4e-52 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NHPPAGDG_03828 1.5e-57 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NHPPAGDG_03829 5.5e-63 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NHPPAGDG_03830 2.5e-121 comB 3.1.3.71 H Belongs to the ComB family
NHPPAGDG_03831 3.5e-140 yitD 4.4.1.19 S synthase
NHPPAGDG_03832 1.1e-107 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHPPAGDG_03833 1e-144 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NHPPAGDG_03834 5.3e-67 S TIGRFAM germination protein, Ger(x)C family
NHPPAGDG_03835 3.6e-99 EG Spore germination protein
NHPPAGDG_03836 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPPAGDG_03837 6.6e-93 ynaD J Acetyltransferase (GNAT) domain
NHPPAGDG_03838 6e-90 ynaC
NHPPAGDG_03839 2.5e-40 ynaC
NHPPAGDG_03840 1.5e-89 G SMI1-KNR4 cell-wall
NHPPAGDG_03841 3.7e-38
NHPPAGDG_03842 6.2e-85
NHPPAGDG_03843 2.7e-32
NHPPAGDG_03844 1.1e-09
NHPPAGDG_03846 4.8e-247 M nucleic acid phosphodiester bond hydrolysis
NHPPAGDG_03847 2.2e-40
NHPPAGDG_03848 2.8e-24
NHPPAGDG_03849 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
NHPPAGDG_03850 3.3e-68 glnR K transcriptional
NHPPAGDG_03851 9.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NHPPAGDG_03852 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHPPAGDG_03853 8.7e-69 spoVK O stage V sporulation protein K
NHPPAGDG_03854 5.3e-245 cisA2 L Recombinase
NHPPAGDG_03856 2.6e-90 recU L DNA recombination
NHPPAGDG_03857 1.9e-10 K Cro/C1-type HTH DNA-binding domain
NHPPAGDG_03859 3.8e-31 S Macro domain
NHPPAGDG_03865 3.6e-29 sspB S spore protein
NHPPAGDG_03874 6.7e-30
NHPPAGDG_03876 2.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHPPAGDG_03877 8.9e-161 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHPPAGDG_03882 6.8e-75 yosT L Bacterial transcription activator, effector binding domain
NHPPAGDG_03883 3.6e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NHPPAGDG_03884 1.4e-09
NHPPAGDG_03886 5.4e-51 pth_2 3.1.1.29 S Peptidyl-tRNA hydrolase PTH2
NHPPAGDG_03888 6.4e-35 O Glutaredoxin
NHPPAGDG_03889 1e-67 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPPAGDG_03891 2.4e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPPAGDG_03892 3.6e-195 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPPAGDG_03893 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPPAGDG_03894 1.5e-65 S NrdI Flavodoxin like
NHPPAGDG_03896 3.3e-135 S HNH endonuclease
NHPPAGDG_03903 1.2e-25 S hydrolase activity
NHPPAGDG_03909 4.8e-68 yhdJ 2.1.1.72 L DNA methylase
NHPPAGDG_03910 2.4e-77 yhdJ 2.1.1.72 L DNA methylase
NHPPAGDG_03911 3.5e-91 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NHPPAGDG_03912 2.8e-85 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
NHPPAGDG_03917 2e-108 DR0488 S protein conserved in bacteria
NHPPAGDG_03918 0.0 S Bacterial DNA polymerase III alpha subunit
NHPPAGDG_03919 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NHPPAGDG_03920 1.6e-221 L DNA primase activity
NHPPAGDG_03921 1.1e-281 3.6.4.12 J DnaB-like helicase C terminal domain
NHPPAGDG_03922 2.6e-85
NHPPAGDG_03923 7.6e-180 L AAA domain
NHPPAGDG_03924 2.8e-168
NHPPAGDG_03929 8.5e-162
NHPPAGDG_03930 1.1e-31 S YopX protein
NHPPAGDG_03931 5.7e-185
NHPPAGDG_03933 4.7e-128 yoqW S Belongs to the SOS response-associated peptidase family
NHPPAGDG_03934 2.9e-148 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
NHPPAGDG_03945 1.2e-65
NHPPAGDG_03953 1.1e-33 K Transcriptional regulator
NHPPAGDG_03954 1.8e-176
NHPPAGDG_03955 6e-263 S DNA-sulfur modification-associated
NHPPAGDG_03956 3.4e-197 L Belongs to the 'phage' integrase family
NHPPAGDG_03961 1.2e-104
NHPPAGDG_03966 2.1e-35 S Protein conserved in bacteria
NHPPAGDG_03971 1.2e-78 L Restriction endonuclease
NHPPAGDG_03973 0.0 S ATP-dependent DNA helicase activity
NHPPAGDG_03975 1.7e-144 S serine-type endopeptidase activity
NHPPAGDG_03976 7.9e-149 S DNA binding
NHPPAGDG_03977 1.1e-204
NHPPAGDG_03978 7.7e-96
NHPPAGDG_03982 0.0 S RNA-directed RNA polymerase activity
NHPPAGDG_03983 5.8e-94
NHPPAGDG_03984 5.5e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHPPAGDG_03989 8.5e-229 S hydrolase activity
NHPPAGDG_03993 2.6e-174
NHPPAGDG_03994 1.3e-44 yfhJ S WVELL protein
NHPPAGDG_03995 6.2e-20 sspK S reproduction
NHPPAGDG_03996 1.6e-208 yfhI EGP Major facilitator Superfamily
NHPPAGDG_03998 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NHPPAGDG_03999 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NHPPAGDG_04000 7.9e-171 yfhF S nucleoside-diphosphate sugar epimerase
NHPPAGDG_04001 2.1e-25 yfhD S YfhD-like protein
NHPPAGDG_04002 3.9e-107 yfhC C nitroreductase
NHPPAGDG_04003 5.3e-164 yfhB 5.3.3.17 S PhzF family
NHPPAGDG_04004 4.4e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_04005 9.9e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_04006 6.3e-174 yfiY P ABC transporter substrate-binding protein
NHPPAGDG_04007 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHPPAGDG_04008 4.9e-79 yfiV K transcriptional
NHPPAGDG_04009 2.6e-283 yfiU EGP Major facilitator Superfamily
NHPPAGDG_04010 1.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
NHPPAGDG_04011 9.3e-195 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NHPPAGDG_04012 1.3e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NHPPAGDG_04013 8.3e-99 padR K transcriptional
NHPPAGDG_04014 8.9e-52 J Acetyltransferase (GNAT) domain
NHPPAGDG_04015 1.8e-204 V COG0842 ABC-type multidrug transport system, permease component
NHPPAGDG_04016 3.3e-209 V ABC-2 family transporter protein
NHPPAGDG_04017 1.5e-169 V ABC transporter, ATP-binding protein
NHPPAGDG_04018 6.9e-97 KT LuxR family transcriptional regulator
NHPPAGDG_04019 1.8e-212 yxjM T Histidine kinase
NHPPAGDG_04021 1.1e-230 S Oxidoreductase
NHPPAGDG_04022 3.2e-183 G Xylose isomerase
NHPPAGDG_04023 3.2e-259 iolT EGP Major facilitator Superfamily
NHPPAGDG_04024 3e-173 K AraC-like ligand binding domain
NHPPAGDG_04025 2.8e-162 yfiE 1.13.11.2 S glyoxalase
NHPPAGDG_04026 6.4e-64 mhqP S DoxX
NHPPAGDG_04027 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NHPPAGDG_04028 1.1e-306 yfiB3 V ABC transporter
NHPPAGDG_04029 3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPPAGDG_04030 7.9e-140 glvR K Helix-turn-helix domain, rpiR family
NHPPAGDG_04031 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NHPPAGDG_04032 7.4e-44 yfjA S Belongs to the WXG100 family
NHPPAGDG_04033 1.8e-186 yfjB
NHPPAGDG_04034 4.1e-144 yfjC
NHPPAGDG_04035 6.9e-101 yfjD S Family of unknown function (DUF5381)
NHPPAGDG_04036 5.2e-56 yfjF S UPF0060 membrane protein
NHPPAGDG_04037 1.2e-25 sspH S Belongs to the SspH family
NHPPAGDG_04038 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NHPPAGDG_04039 3.9e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHPPAGDG_04040 2.4e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHPPAGDG_04041 3.8e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHPPAGDG_04042 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHPPAGDG_04043 6.6e-29 yfjL
NHPPAGDG_04044 1.9e-85 yfjM S Psort location Cytoplasmic, score
NHPPAGDG_04045 9.3e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHPPAGDG_04046 5.1e-44 S YfzA-like protein
NHPPAGDG_04047 3.4e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHPPAGDG_04048 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NHPPAGDG_04049 4e-181 corA P Mediates influx of magnesium ions
NHPPAGDG_04050 4.4e-27 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NHPPAGDG_04051 1.6e-109 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NHPPAGDG_04052 3.8e-153 pdaA G deacetylase
NHPPAGDG_04053 1.1e-26 yfjT
NHPPAGDG_04054 5.4e-222 yfkA S YfkB-like domain
NHPPAGDG_04055 2.3e-148 yfkC M Mechanosensitive ion channel
NHPPAGDG_04056 2e-146 yfkD S YfkD-like protein
NHPPAGDG_04057 6.1e-183 cax P COG0387 Ca2 H antiporter
NHPPAGDG_04058 1.7e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NHPPAGDG_04060 1.3e-143 yihY S Belongs to the UPF0761 family
NHPPAGDG_04061 2.4e-50 yfkI S gas vesicle protein
NHPPAGDG_04062 6.3e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHPPAGDG_04063 1.3e-28 yfkK S Belongs to the UPF0435 family
NHPPAGDG_04064 4.4e-206 ydiM EGP Major facilitator Superfamily
NHPPAGDG_04065 5.2e-87 yfkM 1.11.1.6, 3.5.1.124 S protease
NHPPAGDG_04066 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NHPPAGDG_04067 1.5e-123 yfkO C nitroreductase
NHPPAGDG_04068 1.8e-133 treR K transcriptional
NHPPAGDG_04069 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NHPPAGDG_04070 5.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPPAGDG_04071 5.9e-113 yfkQ EG Spore germination protein
NHPPAGDG_04072 6e-67 yhdN S Domain of unknown function (DUF1992)
NHPPAGDG_04073 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NHPPAGDG_04074 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NHPPAGDG_04075 1.2e-137 map 3.4.11.18 E Methionine aminopeptidase
NHPPAGDG_04076 5.3e-50 yflH S Protein of unknown function (DUF3243)
NHPPAGDG_04077 4.1e-19 yflI
NHPPAGDG_04078 8.9e-18 yflJ S Protein of unknown function (DUF2639)
NHPPAGDG_04079 1.1e-121 yflK S protein conserved in bacteria
NHPPAGDG_04080 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NHPPAGDG_04081 3.3e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NHPPAGDG_04082 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NHPPAGDG_04083 8.5e-227 citM C Citrate transporter
NHPPAGDG_04084 2.4e-178 yflP S Tripartite tricarboxylate transporter family receptor
NHPPAGDG_04085 2.2e-117 citT T response regulator
NHPPAGDG_04086 2e-286 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NHPPAGDG_04087 5.6e-235 yflS P Sodium:sulfate symporter transmembrane region
NHPPAGDG_04088 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NHPPAGDG_04089 7.6e-58 yflT S Heat induced stress protein YflT
NHPPAGDG_04090 2.9e-24 S Protein of unknown function (DUF3212)
NHPPAGDG_04091 3.3e-164 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NHPPAGDG_04092 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_04093 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPPAGDG_04094 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NHPPAGDG_04095 1e-41
NHPPAGDG_04097 5.4e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NHPPAGDG_04098 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NHPPAGDG_04099 5.7e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NHPPAGDG_04100 1.1e-62 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NHPPAGDG_04101 1.5e-152 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NHPPAGDG_04102 9e-148 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NHPPAGDG_04103 7.3e-135 yurK K UTRA
NHPPAGDG_04104 1.5e-195 msmX P Belongs to the ABC transporter superfamily
NHPPAGDG_04106 9e-80 I Fatty acid desaturase
NHPPAGDG_04107 1.3e-22 I Fatty acid desaturase
NHPPAGDG_04108 1.8e-170 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E methionine gamma-lyase
NHPPAGDG_04109 4.1e-42 S B3/4 domain
NHPPAGDG_04110 9.5e-67 L COG3666 Transposase and inactivated derivatives
NHPPAGDG_04111 8.8e-36 L COG3666 Transposase and inactivated derivatives
NHPPAGDG_04112 1.2e-157 gntR9 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPPAGDG_04113 9.3e-74 azlC E AzlC protein
NHPPAGDG_04114 1.9e-23 S branched-chain amino acid
NHPPAGDG_04115 3.8e-167 bsn L Ribonuclease
NHPPAGDG_04116 3.4e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NHPPAGDG_04117 8.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NHPPAGDG_04118 5e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NHPPAGDG_04119 1.2e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NHPPAGDG_04120 4.3e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NHPPAGDG_04121 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NHPPAGDG_04122 4e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NHPPAGDG_04123 1e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NHPPAGDG_04124 1.6e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NHPPAGDG_04125 2.1e-222 pbuX F xanthine
NHPPAGDG_04126 6.7e-235 pbuX F Permease family
NHPPAGDG_04127 3.2e-300 pucR QT COG2508 Regulator of polyketide synthase expression
NHPPAGDG_04128 4.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NHPPAGDG_04129 6.6e-46 yunG
NHPPAGDG_04130 4.3e-171 yunF S Protein of unknown function DUF72
NHPPAGDG_04131 5.9e-141 yunE S membrane transporter protein
NHPPAGDG_04132 1.6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NHPPAGDG_04133 2e-46 yunC S Domain of unknown function (DUF1805)
NHPPAGDG_04134 4.6e-132 yunB S Sporulation protein YunB (Spo_YunB)
NHPPAGDG_04135 1.3e-195 lytH M Peptidase, M23
NHPPAGDG_04136 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHPPAGDG_04137 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHPPAGDG_04138 1.1e-46 yutD S protein conserved in bacteria
NHPPAGDG_04139 1e-75 yutE S Protein of unknown function DUF86
NHPPAGDG_04140 3.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHPPAGDG_04141 5.6e-86 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NHPPAGDG_04142 8.5e-198 yutH S Spore coat protein
NHPPAGDG_04143 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
NHPPAGDG_04144 5.2e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NHPPAGDG_04145 4.3e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHPPAGDG_04146 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NHPPAGDG_04147 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NHPPAGDG_04148 1.1e-55 yuzD S protein conserved in bacteria
NHPPAGDG_04149 7.7e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NHPPAGDG_04150 3.2e-39 yuzB S Belongs to the UPF0349 family
NHPPAGDG_04151 3.5e-198 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NHPPAGDG_04152 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHPPAGDG_04153 3.7e-63 erpA S Belongs to the HesB IscA family
NHPPAGDG_04154 4.3e-49 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPPAGDG_04155 6.1e-114 paiB K Putative FMN-binding domain
NHPPAGDG_04156 1.8e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHPPAGDG_04158 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
NHPPAGDG_04159 1.6e-235 yumB 1.6.99.3 C NADH dehydrogenase
NHPPAGDG_04160 3.2e-26 yuiB S Putative membrane protein
NHPPAGDG_04161 6.8e-116 yuiC S protein conserved in bacteria
NHPPAGDG_04162 2e-77 yuiD S protein conserved in bacteria
NHPPAGDG_04163 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NHPPAGDG_04164 7.4e-210 yuiF S antiporter
NHPPAGDG_04165 1.1e-93 bioY S Biotin biosynthesis protein
NHPPAGDG_04166 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NHPPAGDG_04167 3.9e-167 besA S Putative esterase
NHPPAGDG_04168 5.2e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPPAGDG_04169 4.7e-224 entC 5.4.4.2 HQ Isochorismate synthase
NHPPAGDG_04170 2.2e-311 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NHPPAGDG_04171 1.3e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NHPPAGDG_04172 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPPAGDG_04173 8.5e-36 mbtH S MbtH-like protein
NHPPAGDG_04174 5.4e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NHPPAGDG_04175 5.2e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NHPPAGDG_04176 3.6e-227 yukF QT Transcriptional regulator
NHPPAGDG_04177 2.8e-45 esxA S Belongs to the WXG100 family
NHPPAGDG_04178 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NHPPAGDG_04179 1.7e-209 essB S WXG100 protein secretion system (Wss), protein YukC
NHPPAGDG_04180 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NHPPAGDG_04181 0.0 esaA S type VII secretion protein EsaA
NHPPAGDG_04182 6.6e-65 yueC S Family of unknown function (DUF5383)
NHPPAGDG_04183 9.2e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPPAGDG_04184 1.1e-95 yueE S phosphohydrolase
NHPPAGDG_04185 1.1e-23 S Protein of unknown function (DUF2642)
NHPPAGDG_04186 5.2e-71 S Protein of unknown function (DUF2283)
NHPPAGDG_04187 7.8e-189 yueF S transporter activity
NHPPAGDG_04188 6.6e-31 yueG S Spore germination protein gerPA/gerPF
NHPPAGDG_04189 6.3e-38 yueH S YueH-like protein
NHPPAGDG_04190 3.6e-67 yueI S Protein of unknown function (DUF1694)
NHPPAGDG_04191 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
NHPPAGDG_04192 1e-265 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHPPAGDG_04193 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NHPPAGDG_04194 1.1e-22 yuzC
NHPPAGDG_04196 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
NHPPAGDG_04198 0.0 comP 2.7.13.3 T Histidine kinase
NHPPAGDG_04199 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPPAGDG_04200 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NHPPAGDG_04201 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NHPPAGDG_04202 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHPPAGDG_04203 2.4e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHPPAGDG_04204 2.1e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHPPAGDG_04205 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHPPAGDG_04206 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHPPAGDG_04207 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NHPPAGDG_04208 3.2e-14
NHPPAGDG_04209 1.3e-233 maeN C COG3493 Na citrate symporter
NHPPAGDG_04210 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NHPPAGDG_04211 4.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
NHPPAGDG_04212 2.7e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NHPPAGDG_04213 4.9e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NHPPAGDG_04214 6.6e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NHPPAGDG_04215 1.3e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NHPPAGDG_04216 1.8e-77 yufK S Family of unknown function (DUF5366)
NHPPAGDG_04217 1.8e-74 yuxK S protein conserved in bacteria
NHPPAGDG_04218 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NHPPAGDG_04219 1.2e-183 yuxJ EGP Major facilitator Superfamily
NHPPAGDG_04221 2.7e-114 kapD L the KinA pathway to sporulation
NHPPAGDG_04222 4.1e-68 kapB G Kinase associated protein B
NHPPAGDG_04223 1.7e-232 T PhoQ Sensor
NHPPAGDG_04224 8.4e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NHPPAGDG_04225 4.6e-39 yugE S Domain of unknown function (DUF1871)
NHPPAGDG_04226 4.9e-156 yugF I Hydrolase
NHPPAGDG_04227 1.6e-85 alaR K Transcriptional regulator
NHPPAGDG_04228 2.1e-199 yugH 2.6.1.1 E Aminotransferase
NHPPAGDG_04229 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NHPPAGDG_04230 1.1e-34 yuzA S Domain of unknown function (DUF378)
NHPPAGDG_04231 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NHPPAGDG_04232 2.8e-229 yugK C Dehydrogenase
NHPPAGDG_04233 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NHPPAGDG_04235 1.4e-71 yugN S YugN-like family
NHPPAGDG_04236 8.2e-182 yugO P COG1226 Kef-type K transport systems
NHPPAGDG_04237 1.2e-52 mstX S Membrane-integrating protein Mistic
NHPPAGDG_04238 3.7e-36
NHPPAGDG_04239 1.4e-116 yugP S Zn-dependent protease
NHPPAGDG_04240 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NHPPAGDG_04241 4.1e-222 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NHPPAGDG_04242 1.8e-71 yugU S Uncharacterised protein family UPF0047
NHPPAGDG_04243 1.8e-35
NHPPAGDG_04244 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NHPPAGDG_04245 6e-224 mcpA NT chemotaxis protein
NHPPAGDG_04246 2.6e-175 mcpA NT chemotaxis protein
NHPPAGDG_04247 2.8e-41 mcpA NT chemotaxis protein
NHPPAGDG_04248 2.7e-293 mcpA NT chemotaxis protein
NHPPAGDG_04249 7.3e-238 mcpA NT chemotaxis protein
NHPPAGDG_04250 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NHPPAGDG_04251 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NHPPAGDG_04252 1.8e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NHPPAGDG_04253 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NHPPAGDG_04254 9.7e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NHPPAGDG_04255 9.7e-183 ygjR S Oxidoreductase
NHPPAGDG_04256 1.3e-194 yubA S transporter activity
NHPPAGDG_04257 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHPPAGDG_04259 6.5e-81 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NHPPAGDG_04260 2.7e-272 yubD P Major Facilitator Superfamily
NHPPAGDG_04261 1.5e-149 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHPPAGDG_04262 1e-38 yiaA S yiaA/B two helix domain
NHPPAGDG_04263 1.6e-236 ktrB P Potassium
NHPPAGDG_04264 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)