ORF_ID e_value Gene_name EC_number CAZy COGs Description
OBOLLGII_00001 1.2e-70 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OBOLLGII_00002 3.6e-218 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OBOLLGII_00003 1.8e-18 S YhfH-like protein
OBOLLGII_00004 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OBOLLGII_00005 1.2e-29 ykzG S Belongs to the UPF0356 family
OBOLLGII_00006 7.3e-203 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OBOLLGII_00007 1e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OBOLLGII_00008 3.7e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OBOLLGII_00009 4.8e-260 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OBOLLGII_00010 2.3e-32
OBOLLGII_00012 9.4e-275 speA 4.1.1.19 E Arginine
OBOLLGII_00013 4.5e-48 yktA S Belongs to the UPF0223 family
OBOLLGII_00014 3.6e-119 yktB S Belongs to the UPF0637 family
OBOLLGII_00015 4e-24
OBOLLGII_00016 8.7e-150 suhB 3.1.3.25 G Inositol monophosphatase
OBOLLGII_00017 6e-25 S Family of unknown function (DUF5325)
OBOLLGII_00018 0.0 typA T GTP-binding protein TypA
OBOLLGII_00019 2.1e-52 ylaH S YlaH-like protein
OBOLLGII_00020 2.6e-247 phoH T ATPase related to phosphate starvation-inducible protein PhoH
OBOLLGII_00021 9.1e-89 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OBOLLGII_00022 1.5e-43 ylaN S Belongs to the UPF0358 family
OBOLLGII_00023 4.4e-217 ftsW D Belongs to the SEDS family
OBOLLGII_00024 1.2e-174 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OBOLLGII_00025 1.6e-163 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OBOLLGII_00026 4.9e-196 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OBOLLGII_00027 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OBOLLGII_00028 2.1e-114 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OBOLLGII_00029 9.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OBOLLGII_00030 1.7e-168 ctaG S cytochrome c oxidase
OBOLLGII_00031 9.6e-64 ylbA S YugN-like family
OBOLLGII_00032 3.9e-167 ylbC S protein with SCP PR1 domains
OBOLLGII_00033 1.7e-84 yiiD Q protein, possibly involved in aromatic compounds catabolism
OBOLLGII_00034 2e-70 ylbD S Putative coat protein
OBOLLGII_00035 7.9e-38 ylbE S YlbE-like protein
OBOLLGII_00036 1.9e-62
OBOLLGII_00037 2.8e-73 ylbF S Belongs to the UPF0342 family
OBOLLGII_00038 4.1e-45 ylbG S UPF0298 protein
OBOLLGII_00039 7.7e-67 S Methylthioribose kinase
OBOLLGII_00040 1.7e-105 rsmD 2.1.1.171 L Methyltransferase
OBOLLGII_00041 6.6e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OBOLLGII_00042 5.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
OBOLLGII_00043 7.6e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
OBOLLGII_00044 6.5e-193 ylbL T Belongs to the peptidase S16 family
OBOLLGII_00046 6.3e-224 ylbM S Belongs to the UPF0348 family
OBOLLGII_00047 1.2e-93 yceD S metal-binding, possibly nucleic acid-binding protein
OBOLLGII_00048 1.1e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OBOLLGII_00049 1.6e-80 rsfA S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OBOLLGII_00050 2.3e-92 ylbP K n-acetyltransferase
OBOLLGII_00051 3e-159 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OBOLLGII_00052 0.0 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OBOLLGII_00053 1.4e-77 mraZ K Belongs to the MraZ family
OBOLLGII_00054 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OBOLLGII_00055 1.7e-39 ftsL D Essential cell division protein
OBOLLGII_00056 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OBOLLGII_00057 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
OBOLLGII_00058 4.8e-279 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OBOLLGII_00059 4.9e-78 murF 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OBOLLGII_00060 2.5e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OBOLLGII_00061 1.3e-257 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OBOLLGII_00062 7.7e-189 spoVE D Belongs to the SEDS family
OBOLLGII_00063 1.1e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OBOLLGII_00064 1.1e-117 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OBOLLGII_00065 6.4e-219 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OBOLLGII_00066 3.6e-189 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OBOLLGII_00067 4e-164 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OBOLLGII_00068 3.5e-113 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OBOLLGII_00069 1.8e-136 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OBOLLGII_00070 1.5e-43 ylmC S sporulation protein
OBOLLGII_00071 2.6e-73 yocH CBM50 M 3D domain
OBOLLGII_00072 8.2e-159 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
OBOLLGII_00073 7.3e-121 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OBOLLGII_00074 1.1e-64 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OBOLLGII_00075 1.4e-38 yggT S membrane
OBOLLGII_00076 3.7e-145 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
OBOLLGII_00077 2.5e-65 divIVA D Cell division initiation protein
OBOLLGII_00078 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OBOLLGII_00080 1.3e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OBOLLGII_00081 7.9e-179 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OBOLLGII_00082 9.7e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OBOLLGII_00083 1.2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OBOLLGII_00084 6.1e-257 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OBOLLGII_00085 3.8e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OBOLLGII_00086 0.0 carB 6.3.5.5 F Belongs to the CarB family
OBOLLGII_00087 2.8e-140 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OBOLLGII_00088 4e-181 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OBOLLGII_00089 3.3e-124 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OBOLLGII_00090 3.2e-110 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OBOLLGII_00092 2.6e-166 S Nuclease-related domain
OBOLLGII_00093 6.8e-209 L Transposase IS4 family protein
OBOLLGII_00094 6.8e-16 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 G Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
OBOLLGII_00095 3.8e-75 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
OBOLLGII_00096 7.1e-23 S double-stranded DNA endodeoxyribonuclease activity
OBOLLGII_00097 8e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OBOLLGII_00098 9e-224 EGP Major facilitator Superfamily
OBOLLGII_00099 1.7e-109 lmrB EGP the major facilitator superfamily
OBOLLGII_00100 3.2e-193 S AI-2E family transporter
OBOLLGII_00101 5e-88 L Transposase IS116/IS110/IS902 family
OBOLLGII_00102 1.9e-106 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OBOLLGII_00103 9.6e-167 yocS S -transporter
OBOLLGII_00104 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OBOLLGII_00105 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
OBOLLGII_00106 1.3e-151 yicC S stress-induced protein
OBOLLGII_00107 1.1e-44 ylzA S Belongs to the UPF0296 family
OBOLLGII_00108 3.7e-108 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OBOLLGII_00109 3.4e-29 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OBOLLGII_00110 1.1e-220 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OBOLLGII_00111 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OBOLLGII_00112 1.9e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OBOLLGII_00113 1.7e-179 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OBOLLGII_00114 5.8e-255 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OBOLLGII_00115 1.5e-135 stp 3.1.3.16 T phosphatase
OBOLLGII_00116 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OBOLLGII_00117 5.7e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OBOLLGII_00118 6.8e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OBOLLGII_00119 6.8e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
OBOLLGII_00120 5e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OBOLLGII_00121 8.5e-265 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00122 1.9e-59 asp S protein conserved in bacteria
OBOLLGII_00123 3e-301 yloV S kinase related to dihydroxyacetone kinase
OBOLLGII_00124 1.3e-119 sdaAB 4.3.1.17 E L-serine dehydratase
OBOLLGII_00125 2.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
OBOLLGII_00126 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OBOLLGII_00127 8.8e-99 fapR 5.3.1.23 Q Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OBOLLGII_00128 2.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OBOLLGII_00129 4.2e-159 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OBOLLGII_00130 2.1e-129 IQ reductase
OBOLLGII_00131 3.7e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OBOLLGII_00132 1.5e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OBOLLGII_00133 0.0 smc D Required for chromosome condensation and partitioning
OBOLLGII_00134 1.3e-179 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OBOLLGII_00135 2.9e-51 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OBOLLGII_00136 8.7e-243 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OBOLLGII_00137 1.7e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OBOLLGII_00138 5.5e-36 ylqC S Belongs to the UPF0109 family
OBOLLGII_00139 7.1e-60 ylqD S YlqD protein
OBOLLGII_00140 1.2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OBOLLGII_00141 2e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OBOLLGII_00142 2.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OBOLLGII_00143 1.2e-102 lepB 3.4.21.89 U Belongs to the peptidase S26 family
OBOLLGII_00144 4.7e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OBOLLGII_00145 1.7e-129 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OBOLLGII_00146 2.8e-227 CP_1081 D nuclear chromosome segregation
OBOLLGII_00147 3.6e-45 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
OBOLLGII_00148 1.6e-213 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OBOLLGII_00149 2.2e-165 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OBOLLGII_00150 1.2e-160 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
OBOLLGII_00151 8.8e-103 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00152 3.7e-134 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00153 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OBOLLGII_00154 4.3e-169 xerC L tyrosine recombinase XerC
OBOLLGII_00155 7.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OBOLLGII_00156 2.1e-226 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OBOLLGII_00157 3.3e-133 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OBOLLGII_00158 5.7e-62 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OBOLLGII_00159 4e-75 flgC N Belongs to the flagella basal body rod proteins family
OBOLLGII_00160 6.4e-40 fliE N Flagellar hook-basal body complex protein FliE
OBOLLGII_00161 6.5e-245 fliF N The M ring may be actively involved in energy transduction
OBOLLGII_00162 1.1e-162 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OBOLLGII_00163 3.5e-124 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
OBOLLGII_00164 7.3e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OBOLLGII_00165 1.6e-68 fliJ N Flagellar biosynthesis chaperone
OBOLLGII_00166 2.7e-37 ylxF S MgtE intracellular N domain
OBOLLGII_00167 6.9e-292 fliK N Flagellar hook-length control
OBOLLGII_00168 2.3e-108 flgD N Flagellar basal body rod modification protein
OBOLLGII_00169 3.2e-72 flg N Putative flagellar
OBOLLGII_00170 3.1e-115 flgG N Flagellar basal body rod
OBOLLGII_00171 1.3e-64 fliL N Controls the rotational direction of flagella during chemotaxis
OBOLLGII_00172 3.4e-183 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OBOLLGII_00173 1.2e-173 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OBOLLGII_00174 2.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
OBOLLGII_00175 3.2e-116 fliZ N Flagellar biosynthesis protein, FliO
OBOLLGII_00176 2.6e-107 fliP N Plays a role in the flagellum-specific transport system
OBOLLGII_00177 1.5e-37 fliQ N Role in flagellar biosynthesis
OBOLLGII_00178 8.6e-134 fliR N Flagellar biosynthetic protein FliR
OBOLLGII_00179 3.5e-186 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OBOLLGII_00180 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OBOLLGII_00181 4.9e-194 flhF N Flagellar biosynthesis regulator FlhF
OBOLLGII_00182 1.2e-144 flhG D Belongs to the ParA family
OBOLLGII_00183 3.2e-113 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OBOLLGII_00184 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
OBOLLGII_00185 8.2e-70 cheW NT COG0835 Chemotaxis signal transduction protein
OBOLLGII_00186 1.2e-112 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OBOLLGII_00187 8.9e-84 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OBOLLGII_00188 1.1e-136 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OBOLLGII_00189 2.4e-74 ylxL
OBOLLGII_00190 3.4e-135 rpsB J Belongs to the universal ribosomal protein uS2 family
OBOLLGII_00191 1.8e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OBOLLGII_00192 1.1e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OBOLLGII_00193 6.9e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OBOLLGII_00194 1.1e-147 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OBOLLGII_00195 3.2e-144 cdsA 2.7.7.41 S Belongs to the CDS family
OBOLLGII_00196 3.7e-194 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OBOLLGII_00197 3.3e-236 rasP M zinc metalloprotease
OBOLLGII_00198 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OBOLLGII_00199 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OBOLLGII_00200 7.1e-83 rimP S Required for maturation of 30S ribosomal subunits
OBOLLGII_00201 2.8e-224 nusA K Participates in both transcription termination and antitermination
OBOLLGII_00202 8.2e-45 ylxR K nucleic-acid-binding protein implicated in transcription termination
OBOLLGII_00203 2.9e-48 ylxQ J ribosomal protein
OBOLLGII_00204 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OBOLLGII_00205 8.6e-44 ylxP S protein conserved in bacteria
OBOLLGII_00206 3.2e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OBOLLGII_00207 2.4e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OBOLLGII_00208 3.6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OBOLLGII_00209 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OBOLLGII_00210 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OBOLLGII_00211 1.2e-208 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
OBOLLGII_00212 2.4e-231 pepR S Belongs to the peptidase M16 family
OBOLLGII_00213 1.4e-37 ymxH S YlmC YmxH family
OBOLLGII_00214 2.5e-186 dpaA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
OBOLLGII_00215 2.6e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OBOLLGII_00216 9.9e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OBOLLGII_00217 1.1e-228 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OBOLLGII_00218 3.9e-159 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OBOLLGII_00219 0.0 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OBOLLGII_00221 2.2e-131 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
OBOLLGII_00222 4.3e-35 S YlzJ-like protein
OBOLLGII_00223 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OBOLLGII_00224 9.1e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OBOLLGII_00225 8e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OBOLLGII_00226 5.8e-186 yufP S Belongs to the binding-protein-dependent transport system permease family
OBOLLGII_00227 1.8e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
OBOLLGII_00228 2.1e-238 ymfF S Peptidase M16
OBOLLGII_00229 2e-244 ymfH S zinc protease
OBOLLGII_00230 5e-128 1.1.1.100 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OBOLLGII_00231 6.4e-41 ymfJ S Protein of unknown function (DUF3243)
OBOLLGII_00232 1e-142 ymfK S Protein of unknown function (DUF3388)
OBOLLGII_00233 1.1e-135 ymfM S protein conserved in bacteria
OBOLLGII_00234 1.3e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OBOLLGII_00235 2.4e-223 cinA 3.5.1.42 S Belongs to the CinA family
OBOLLGII_00236 4.9e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OBOLLGII_00237 1.2e-216 rny S Endoribonuclease that initiates mRNA decay
OBOLLGII_00238 1.9e-152 ymdB S protein conserved in bacteria
OBOLLGII_00239 3.3e-37 spoVS S Stage V sporulation protein S
OBOLLGII_00240 3.7e-168 yegQ O Peptidase U32
OBOLLGII_00241 5.5e-247 yegQ O COG0826 Collagenase and related proteases
OBOLLGII_00242 5.6e-212 E Amino acid permease
OBOLLGII_00243 5.2e-300 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OBOLLGII_00244 2.1e-49 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OBOLLGII_00245 6.2e-99 cotE S Outer spore coat protein E (CotE)
OBOLLGII_00246 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OBOLLGII_00247 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OBOLLGII_00248 5.5e-40 yhjA S Excalibur calcium-binding domain
OBOLLGII_00249 1.1e-12 2.1.1.80, 3.1.1.61 S protein secretion by the type IV secretion system
OBOLLGII_00252 5.3e-187 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OBOLLGII_00253 1.2e-35 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OBOLLGII_00254 6e-174 spoVK O stage V sporulation protein K
OBOLLGII_00255 3.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OBOLLGII_00256 2.1e-246 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OBOLLGII_00257 4.6e-171 polA 2.7.7.7 L 5'3' exonuclease
OBOLLGII_00258 3.6e-27 ypeQ S Zinc-finger
OBOLLGII_00260 1.2e-31 cspD K Cold-shock protein
OBOLLGII_00261 3e-72 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OBOLLGII_00262 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
OBOLLGII_00263 3.3e-86
OBOLLGII_00264 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OBOLLGII_00265 1.3e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
OBOLLGII_00266 2.3e-75 yphP S Belongs to the UPF0403 family
OBOLLGII_00267 1.3e-105 ypjP S YpjP-like protein
OBOLLGII_00268 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OBOLLGII_00269 3.5e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OBOLLGII_00270 1.9e-110 hlyIII S protein, Hemolysin III
OBOLLGII_00271 1.2e-146 ypmR E COG2755 Lysophospholipase L1 and related esterases
OBOLLGII_00272 9.3e-98 ypmS S protein conserved in bacteria
OBOLLGII_00273 6.1e-276 rsmF 2.1.1.176, 2.1.1.178 J RNA-binding PUA-like domain of methyltransferase RsmF
OBOLLGII_00274 1.6e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OBOLLGII_00275 1.6e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OBOLLGII_00276 1.2e-09 S Protein of unknown function (Tiny_TM_bacill)
OBOLLGII_00277 2.1e-191 NT CHASE3 domain
OBOLLGII_00278 7.5e-35 yozE S Belongs to the UPF0346 family
OBOLLGII_00279 4.3e-115 yodN
OBOLLGII_00280 7.5e-25 yozD S YozD-like protein
OBOLLGII_00281 2e-146 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OBOLLGII_00282 2.4e-270 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OBOLLGII_00283 2.5e-66 ypoP K transcriptional
OBOLLGII_00285 5.4e-96 ykwD J protein with SCP PR1 domains
OBOLLGII_00286 3.4e-242 norM V Multidrug efflux pump
OBOLLGII_00288 2.9e-182 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OBOLLGII_00289 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
OBOLLGII_00290 6e-133 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OBOLLGII_00291 8.5e-111 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OBOLLGII_00293 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OBOLLGII_00294 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OBOLLGII_00295 1.8e-221 ymfD EGP Major facilitator Superfamily
OBOLLGII_00296 3.3e-207 L COG3547 Transposase and inactivated derivatives
OBOLLGII_00297 1.3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OBOLLGII_00298 2.7e-250 arlS 2.7.13.3 T Histidine kinase
OBOLLGII_00299 1.3e-260 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00300 1.5e-74 yozR S COG0071 Molecular chaperone (small heat shock protein)
OBOLLGII_00301 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OBOLLGII_00302 8.4e-203 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OBOLLGII_00303 1.7e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
OBOLLGII_00304 3.8e-83 rok S Repressor of ComK
OBOLLGII_00305 1.4e-115 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OBOLLGII_00307 5.2e-159 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OBOLLGII_00308 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OBOLLGII_00309 3.5e-193 yceA S Belongs to the UPF0176 family
OBOLLGII_00310 1.1e-129 yoqW S Belongs to the SOS response-associated peptidase family
OBOLLGII_00311 2.9e-105 thiT S Proton-coupled thiamine transporter YuaJ
OBOLLGII_00312 1.2e-168 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
OBOLLGII_00313 2.1e-79 S Domain in cystathionine beta-synthase and other proteins.
OBOLLGII_00314 2.4e-101 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OBOLLGII_00315 7.8e-55 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OBOLLGII_00316 1.5e-101 yocH CBM50 M COG1388 FOG LysM repeat
OBOLLGII_00317 0.0 topB2 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OBOLLGII_00318 3.5e-247 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
OBOLLGII_00319 1.2e-177 corA P Mg2 transporter protein
OBOLLGII_00320 2.7e-63 S CHY zinc finger
OBOLLGII_00321 1.3e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OBOLLGII_00322 1.8e-110 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OBOLLGII_00323 3.3e-231 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OBOLLGII_00324 2.9e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OBOLLGII_00325 6.1e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OBOLLGII_00326 2.4e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OBOLLGII_00327 1.3e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OBOLLGII_00328 3.1e-116 hisE 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
OBOLLGII_00329 1.7e-40 yedF O Belongs to the sulfur carrier protein TusA family
OBOLLGII_00330 1.8e-239 yedE S Sulphur transport
OBOLLGII_00331 6.1e-161 rarD S -transporter
OBOLLGII_00332 6.5e-219 ktrB P COG0168 Trk-type K transport systems, membrane components
OBOLLGII_00333 3.3e-121 P COG0569 K transport systems, NAD-binding component
OBOLLGII_00334 8.3e-134 ykrK S Domain of unknown function (DUF1836)
OBOLLGII_00335 4.6e-15
OBOLLGII_00336 1.1e-44 yxcD S Protein of unknown function (DUF2653)
OBOLLGII_00337 5.2e-215 yeaN P COG2807 Cyanate permease
OBOLLGII_00338 2.1e-310 ubiB S ABC1 family
OBOLLGII_00339 4.7e-24 S ATP synthase, subunit b
OBOLLGII_00340 7.7e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OBOLLGII_00342 2.7e-31 cspB K Cold shock
OBOLLGII_00343 3.2e-118 folE 3.5.4.16 H GTP cyclohydrolase
OBOLLGII_00344 1e-173 trxB_2 1.8.1.9 C FAD dependent oxidoreductase
OBOLLGII_00345 2.8e-45 S Protein of unknown function (DUF1292)
OBOLLGII_00346 5.2e-47 yxiS
OBOLLGII_00347 0.0 bceB V ABC transporter (permease)
OBOLLGII_00348 1.2e-135 bceA V ABC transporter, ATP-binding protein
OBOLLGII_00349 1.8e-184 bceS 2.7.13.3 T Signal transduction histidine kinase
OBOLLGII_00350 1.6e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OBOLLGII_00351 2.3e-230 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
OBOLLGII_00352 8.3e-191 yetN S Protein of unknown function (DUF3900)
OBOLLGII_00353 8.2e-233 ywoD EGP Major facilitator superfamily
OBOLLGII_00354 1.3e-48 iscA S Heme biosynthesis protein HemY
OBOLLGII_00355 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
OBOLLGII_00356 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
OBOLLGII_00357 9.4e-43 S Small, acid-soluble spore proteins, alpha/beta type
OBOLLGII_00358 3.8e-61 S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OBOLLGII_00359 8.9e-111 M effector of murein hydrolase
OBOLLGII_00360 0.0 alkK IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OBOLLGII_00361 4.4e-109 M lytic transglycosylase activity
OBOLLGII_00362 1.1e-08 S membrane
OBOLLGII_00363 8.6e-19 sspP S Belongs to the SspP family
OBOLLGII_00364 4.5e-39
OBOLLGII_00365 7.1e-239 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OBOLLGII_00366 4.4e-18 sspO S Belongs to the SspO family
OBOLLGII_00367 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OBOLLGII_00369 1.7e-19 sspN S Small acid-soluble spore protein N family
OBOLLGII_00370 4.1e-31 tlp S Belongs to the Tlp family
OBOLLGII_00371 2.2e-75 yneP S thioesterase
OBOLLGII_00372 7.1e-52 yneQ
OBOLLGII_00373 5.3e-52 yneR S Belongs to the HesB IscA family
OBOLLGII_00374 5e-97 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OBOLLGII_00375 1.9e-71 yccU S CoA-binding protein
OBOLLGII_00376 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OBOLLGII_00377 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OBOLLGII_00378 6.3e-145
OBOLLGII_00379 3.2e-215 yjjL G Major facilitator superfamily
OBOLLGII_00380 2.9e-148 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OBOLLGII_00381 0.0 ppdK 2.7.3.13, 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
OBOLLGII_00382 7.8e-55 E Glyoxalase
OBOLLGII_00385 1.1e-198 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OBOLLGII_00386 6.5e-93 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OBOLLGII_00388 2.8e-117 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
OBOLLGII_00389 7.2e-86 yvbK 3.1.3.25 K acetyltransferase
OBOLLGII_00390 2.4e-28 VPA1573 J acetyltransferase
OBOLLGII_00391 2.5e-74 MA20_02285 2.3.1.57 K Acetyltransferase (GNAT) family
OBOLLGII_00392 3e-248 L PFAM Transposase, IS4-like
OBOLLGII_00393 1.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
OBOLLGII_00394 2.7e-122 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OBOLLGII_00395 7e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OBOLLGII_00396 1.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OBOLLGII_00397 2.5e-08 ykyB S YkyB-like protein
OBOLLGII_00398 6.6e-127 yflK S protein conserved in bacteria
OBOLLGII_00399 4.3e-42 S COG NOG14552 non supervised orthologous group
OBOLLGII_00400 4e-297 L PFAM Integrase, catalytic core
OBOLLGII_00401 2.8e-84 2.3.1.57 K Acetyltransferase (GNAT) domain
OBOLLGII_00403 1.4e-218 S Psort location CytoplasmicMembrane, score
OBOLLGII_00404 1.5e-120 yfiR K Transcriptional regulator
OBOLLGII_00405 6.7e-145 yfiS EGP Major facilitator Superfamily
OBOLLGII_00406 2.1e-54 yfiS EGP Major facilitator Superfamily
OBOLLGII_00408 9.6e-138 thiX 2.7.1.50 P binding-protein-dependent transport systems inner membrane component
OBOLLGII_00409 1.6e-177 nrtA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OBOLLGII_00410 2.3e-74 S Glyoxalase bleomycin resistance protein dioxygenase
OBOLLGII_00411 6.3e-139 yitD 4.4.1.19 S synthase
OBOLLGII_00412 5.3e-127 comB 3.1.3.71 H Belongs to the ComB family
OBOLLGII_00413 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OBOLLGII_00414 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OBOLLGII_00415 4.8e-108
OBOLLGII_00416 5.1e-65 mta K transcriptional
OBOLLGII_00417 1.9e-37 mta K transcriptional
OBOLLGII_00419 8e-268 dapE 3.5.1.16, 3.5.1.18 E Peptidase dimerisation domain
OBOLLGII_00420 2.1e-177 yjlA EG Putative multidrug resistance efflux transporter
OBOLLGII_00421 8.2e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OBOLLGII_00422 1.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OBOLLGII_00423 2e-214 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OBOLLGII_00424 4.9e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OBOLLGII_00425 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OBOLLGII_00426 3.7e-180 kefA M Mechanosensitive ion channel
OBOLLGII_00427 5.6e-191 S COG0491 Zn-dependent hydrolases, including glyoxylases
OBOLLGII_00428 1.2e-109 nrdB 1.17.4.1 F Ribonucleotide reductase, small chain
OBOLLGII_00429 4e-104 S Appr-1'-p processing enzyme
OBOLLGII_00430 4.4e-25 sspH S small acid-soluble spore protein
OBOLLGII_00431 2.7e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OBOLLGII_00432 3.2e-209 2.3.1.16, 2.3.1.9 I Belongs to the thiolase family
OBOLLGII_00433 3.3e-291 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OBOLLGII_00434 1.9e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OBOLLGII_00435 5.1e-142 S Sucrose-6F-phosphate phosphohydrolase
OBOLLGII_00436 4.9e-74 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00437 7.3e-138 L SMART ATPase, AAA type, core
OBOLLGII_00438 3.6e-298 L PFAM Integrase, catalytic core
OBOLLGII_00439 4.5e-180 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00440 4.2e-104 yozB S membrane
OBOLLGII_00441 1.7e-58
OBOLLGII_00442 2.5e-75 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OBOLLGII_00443 1.5e-180 ldh1 1.1.1.27 C Belongs to the LDH MDH superfamily
OBOLLGII_00444 1.4e-117 kch P Ion channel
OBOLLGII_00445 4.9e-10
OBOLLGII_00447 1.4e-33 L COG3547 Transposase and inactivated derivatives
OBOLLGII_00448 9.2e-37 T AMP binding
OBOLLGII_00449 1.8e-134 MA20_14895 S Conserved hypothetical protein 698
OBOLLGII_00451 3.8e-59 L HTH-like domain
OBOLLGII_00452 2e-129 cysL K Bacterial regulatory helix-turn-helix protein, lysR family
OBOLLGII_00453 2.4e-105 S HTH-like domain
OBOLLGII_00454 1.3e-23 ymbI L Transposase
OBOLLGII_00455 6.8e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00456 1e-13
OBOLLGII_00457 7e-32
OBOLLGII_00458 1.4e-85 L Mu transposase, C-terminal
OBOLLGII_00459 6.4e-89 L Transposase
OBOLLGII_00460 2.5e-43 L Transposase
OBOLLGII_00461 1.1e-07 L Resolvase, N terminal domain
OBOLLGII_00462 2.7e-97 L Bacterial dnaA protein
OBOLLGII_00463 1.1e-59 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
OBOLLGII_00464 2.4e-179 arsB 1.20.4.1 P Sodium Bile acid symporter family
OBOLLGII_00465 4.2e-66 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
OBOLLGII_00466 6.1e-58 S Arsenical resistance operon trans-acting repressor ArsD
OBOLLGII_00467 2.1e-223 arsA 3.6.3.16 D 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family
OBOLLGII_00468 6.4e-11
OBOLLGII_00469 3.4e-130 U COG3267 Type II secretory pathway, component ExeA
OBOLLGII_00470 2.7e-231 L Mu transposase, C-terminal
OBOLLGII_00472 1e-131 IQ Enoyl-(Acyl carrier protein) reductase
OBOLLGII_00473 1.4e-215 fsr P COG0477 Permeases of the major facilitator superfamily
OBOLLGII_00474 2.2e-75 sleB 3.5.1.28 M Cell wall
OBOLLGII_00475 7.8e-148 xth 3.1.11.2 L exodeoxyribonuclease III
OBOLLGII_00476 3.7e-26 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OBOLLGII_00477 7.7e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
OBOLLGII_00478 7.6e-184 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
OBOLLGII_00479 7.1e-209 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OBOLLGII_00480 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OBOLLGII_00481 6.1e-193 G Glycosyl hydrolases family 15
OBOLLGII_00482 7.3e-21 S YpzG-like protein
OBOLLGII_00483 5e-82 Q protein disulfide oxidoreductase activity
OBOLLGII_00484 7.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
OBOLLGII_00485 5.3e-118 nudL L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OBOLLGII_00486 1.1e-223 mntH P H( )-stimulated, divalent metal cation uptake system
OBOLLGII_00487 1.6e-76 dps P Ferritin-like domain
OBOLLGII_00488 5e-81 V VanZ like family
OBOLLGII_00489 1.9e-167 yhcI S ABC-2 family transporter protein
OBOLLGII_00490 2e-169 ydbJ V ABC transporter, ATP-binding protein
OBOLLGII_00491 6.3e-57
OBOLLGII_00492 6.9e-167 murB 1.3.1.98 M cell wall formation
OBOLLGII_00493 8.1e-80 S Protein of unknown function (DUF1189)
OBOLLGII_00494 1.4e-37 S Protein of unknown function (DUF1450)
OBOLLGII_00495 8.5e-265 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00496 6.1e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OBOLLGII_00497 5.7e-39 I MaoC like domain
OBOLLGII_00498 4.8e-129 IQ Enoyl-(Acyl carrier protein) reductase
OBOLLGII_00499 3.6e-53 dld 1.1.1.303, 1.1.1.4, 1.1.2.4 C Glycolate oxidase subunit
OBOLLGII_00501 6.6e-198 selU S tRNA 2-selenouridine synthase
OBOLLGII_00502 1.4e-192 selD 2.7.9.3 E Synthesizes selenophosphate from selenide and ATP
OBOLLGII_00503 4.4e-132 T Calcineurin-like phosphoesterase superfamily domain
OBOLLGII_00505 3.1e-187 yraQ S Predicted permease
OBOLLGII_00506 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OBOLLGII_00507 2.1e-194 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OBOLLGII_00508 1.9e-72 yjlC S Protein of unknown function (DUF1641)
OBOLLGII_00509 6.3e-221 yjlD 1.6.99.3 C NADH dehydrogenase
OBOLLGII_00510 1.1e-228 nrnB S phosphohydrolase (DHH superfamily)
OBOLLGII_00511 4.5e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OBOLLGII_00512 2e-129 yvpB NU protein conserved in bacteria
OBOLLGII_00513 9.2e-50 tnrA K transcriptional
OBOLLGII_00514 7.9e-108 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OBOLLGII_00515 1.9e-23 S Virus attachment protein p12 family
OBOLLGII_00516 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
OBOLLGII_00517 2.4e-36 feoA P COG1918 Fe2 transport system protein A
OBOLLGII_00518 6.1e-263 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00519 7e-220 dapL 2.6.1.83 E Aminotransferase
OBOLLGII_00520 9.2e-264 argH 4.3.2.1 E argininosuccinate lyase
OBOLLGII_00521 4.8e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OBOLLGII_00522 2.6e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OBOLLGII_00523 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
OBOLLGII_00524 1.5e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OBOLLGII_00525 1.1e-223 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OBOLLGII_00526 4.3e-141 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
OBOLLGII_00527 6.8e-234 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OBOLLGII_00528 2e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OBOLLGII_00530 9.7e-77
OBOLLGII_00531 2.5e-36 P catalase activity
OBOLLGII_00532 1.6e-79
OBOLLGII_00533 2.3e-30 cspD K Cold shock
OBOLLGII_00535 6.7e-170 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OBOLLGII_00536 6.6e-276 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
OBOLLGII_00537 4.4e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OBOLLGII_00538 5.6e-77 yneK S Protein of unknown function (DUF2621)
OBOLLGII_00539 4.6e-77 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
OBOLLGII_00540 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
OBOLLGII_00541 6.4e-128 ccdA O cytochrome c biogenesis protein
OBOLLGII_00542 6.8e-28 yneF S UPF0154 protein
OBOLLGII_00543 5.3e-72 yneE S Sporulation inhibitor of replication protein sirA
OBOLLGII_00544 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OBOLLGII_00545 3.4e-33 ynzC S UPF0291 protein
OBOLLGII_00546 5.2e-116 yneB L resolvase
OBOLLGII_00547 8e-52 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OBOLLGII_00548 1.2e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OBOLLGII_00549 6.4e-262 glnA 6.3.1.2 E glutamine synthetase
OBOLLGII_00550 3e-63 glnR K transcriptional
OBOLLGII_00551 0.0 S Dynamin family
OBOLLGII_00552 5e-33
OBOLLGII_00553 2.4e-142 f42a O prohibitin homologues
OBOLLGII_00554 3e-232 pbuX F xanthine
OBOLLGII_00555 1.6e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OBOLLGII_00556 9.7e-299 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OBOLLGII_00557 2.2e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OBOLLGII_00558 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OBOLLGII_00559 3.4e-100 ypsA S Belongs to the UPF0398 family
OBOLLGII_00560 5.4e-45 cotD S Inner spore coat protein D
OBOLLGII_00561 1.1e-253 yprB L RNase_H superfamily
OBOLLGII_00562 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OBOLLGII_00563 2e-74 hspX O Belongs to the small heat shock protein (HSP20) family
OBOLLGII_00565 9.5e-62 yppG S YppG-like protein
OBOLLGII_00566 1.1e-62 yppE S Bacterial domain of unknown function (DUF1798)
OBOLLGII_00569 1.1e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OBOLLGII_00570 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OBOLLGII_00571 5.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OBOLLGII_00572 2.8e-128 dnaD L DNA replication protein DnaD
OBOLLGII_00573 2e-260 asnS 6.1.1.22 J asparaginyl-tRNA
OBOLLGII_00574 9.5e-217 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OBOLLGII_00575 1.3e-76 ypmB S protein conserved in bacteria
OBOLLGII_00576 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OBOLLGII_00577 7.9e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OBOLLGII_00578 5.9e-160 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OBOLLGII_00579 7.1e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OBOLLGII_00580 2.9e-171 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OBOLLGII_00581 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OBOLLGII_00582 8.8e-215 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
OBOLLGII_00583 6.2e-131 bshB1 S proteins, LmbE homologs
OBOLLGII_00584 2.8e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OBOLLGII_00585 1.7e-57 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
OBOLLGII_00586 2.4e-161 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
OBOLLGII_00587 3.1e-81 queT S QueT transporter
OBOLLGII_00588 3.4e-102 yugP S Zn-dependent protease
OBOLLGII_00589 6e-143 ypjB S sporulation protein
OBOLLGII_00590 1.6e-108 ypjA S membrane
OBOLLGII_00591 1.6e-145 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
OBOLLGII_00592 1.2e-126 petB C COG1290 Cytochrome b subunit of the bc complex
OBOLLGII_00593 1.3e-98 qcrA C Menaquinol-cytochrome c reductase
OBOLLGII_00594 2e-80 ypiF S Protein of unknown function (DUF2487)
OBOLLGII_00595 5.9e-97 ypiB S Belongs to the UPF0302 family
OBOLLGII_00596 1.9e-239 S COG0457 FOG TPR repeat
OBOLLGII_00597 6.7e-232 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OBOLLGII_00598 9.4e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OBOLLGII_00599 7.9e-210 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OBOLLGII_00600 3.8e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OBOLLGII_00601 4.4e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OBOLLGII_00602 1.1e-220 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OBOLLGII_00603 2.4e-144 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
OBOLLGII_00604 7.2e-77 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OBOLLGII_00605 1.9e-170 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OBOLLGII_00606 6.4e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OBOLLGII_00607 3.3e-144 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OBOLLGII_00608 8.7e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OBOLLGII_00609 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OBOLLGII_00610 8.3e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OBOLLGII_00611 1.7e-136 yphF
OBOLLGII_00612 3.2e-08 yphE S Protein of unknown function (DUF2768)
OBOLLGII_00613 1.6e-191 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OBOLLGII_00614 5.5e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OBOLLGII_00615 2.4e-19 yphA
OBOLLGII_00616 7.3e-14 S YpzI-like protein
OBOLLGII_00617 9.4e-206 rpsA 1.17.7.4 J Ribosomal protein S1
OBOLLGII_00618 1.1e-119 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OBOLLGII_00619 8.7e-116 ypfA M Flagellar protein YcgR
OBOLLGII_00620 2.9e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
OBOLLGII_00621 1e-145 sleB 3.5.1.28 M Spore cortex-lytic enzyme
OBOLLGII_00622 1.2e-123 prsW S Involved in the degradation of specific anti-sigma factors
OBOLLGII_00623 3e-184 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
OBOLLGII_00624 4.4e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OBOLLGII_00625 1.4e-107 mecB NOT Negative regulator of genetic competence (MecA)
OBOLLGII_00626 1.8e-144 ypbG S Calcineurin-like phosphoesterase superfamily domain
OBOLLGII_00627 2.6e-30 cotJA S Spore coat associated protein JA (CotJA)
OBOLLGII_00628 1.2e-44 cotJB S CotJB protein
OBOLLGII_00629 1.5e-103 cotJC P Spore Coat
OBOLLGII_00630 1.2e-79 ypbF S Protein of unknown function (DUF2663)
OBOLLGII_00632 1.2e-100 ypbD S metal-dependent membrane protease
OBOLLGII_00633 8.3e-279 recQ 3.6.4.12 L DNA helicase
OBOLLGII_00634 1.1e-203 ypbB 5.1.3.1 S protein conserved in bacteria
OBOLLGII_00635 3.2e-203 L PFAM Transposase, IS4-like
OBOLLGII_00636 7.8e-41 fer C Ferredoxin
OBOLLGII_00637 1.1e-96 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OBOLLGII_00638 4.8e-115 M COG0739 Membrane proteins related to metalloendopeptidases
OBOLLGII_00639 0.0 resE 2.7.13.3 T Histidine kinase
OBOLLGII_00640 3.3e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OBOLLGII_00641 2.2e-229 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OBOLLGII_00642 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OBOLLGII_00643 2.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OBOLLGII_00644 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OBOLLGII_00645 1.4e-87 spmB S Spore maturation protein
OBOLLGII_00646 5.2e-96 spmA S Spore maturation protein
OBOLLGII_00647 8.1e-202 dacB 3.4.16.4 M Belongs to the peptidase S11 family
OBOLLGII_00648 1.2e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OBOLLGII_00649 1.7e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OBOLLGII_00651 2.2e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OBOLLGII_00652 1.6e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OBOLLGII_00653 2.3e-268 spoVAF EG Stage V sporulation protein AF
OBOLLGII_00654 8e-105 spoVAEA S Stage V sporulation protein AE
OBOLLGII_00655 4.6e-65 spoVAB S Stage V sporulation protein AB
OBOLLGII_00656 6.5e-108 spoVAA S Stage V sporulation protein AA
OBOLLGII_00657 1.4e-133 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OBOLLGII_00658 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OBOLLGII_00659 2.5e-56 spoIIAA T Belongs to the anti-sigma-factor antagonist family
OBOLLGII_00660 7.6e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
OBOLLGII_00662 3.6e-168 xerD L recombinase XerD
OBOLLGII_00663 6.3e-34 S Protein of unknown function (DUF4227)
OBOLLGII_00664 3.5e-85 fur P Belongs to the Fur family
OBOLLGII_00665 1.5e-104 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OBOLLGII_00666 1.1e-228 yqxK 3.6.4.12 L DNA helicase
OBOLLGII_00667 1.6e-97 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
OBOLLGII_00669 1.4e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
OBOLLGII_00670 1.6e-09 S Protein of unknown function (DUF3886)
OBOLLGII_00671 5.6e-110 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
OBOLLGII_00672 1.3e-213 yaaN P Belongs to the TelA family
OBOLLGII_00673 8.2e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
OBOLLGII_00674 2.4e-235 yaaH_2 M Glycoside Hydrolase Family
OBOLLGII_00675 6.6e-54 S YolD-like protein
OBOLLGII_00676 1.3e-240 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OBOLLGII_00677 8.5e-145 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
OBOLLGII_00678 6.3e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OBOLLGII_00679 6.5e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OBOLLGII_00680 1.7e-292 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OBOLLGII_00681 1.1e-225 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OBOLLGII_00682 4.2e-76 cheW NT COG0835 Chemotaxis signal transduction protein
OBOLLGII_00683 2.1e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
OBOLLGII_00684 6.1e-263 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00685 3.6e-93 yqjB S protein conserved in bacteria
OBOLLGII_00686 2.1e-76 yqiW S Belongs to the UPF0403 family
OBOLLGII_00687 3.4e-166 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
OBOLLGII_00688 3e-216 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OBOLLGII_00689 3.9e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OBOLLGII_00690 5e-187 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OBOLLGII_00691 1.5e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OBOLLGII_00692 1.5e-208 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
OBOLLGII_00693 9.9e-18 T transcription factor binding
OBOLLGII_00694 1.4e-56 1.1.1.169, 1.3.1.12, 4.2.1.51, 5.4.99.5 E prephenate dehydrogenase (NADP+) activity
OBOLLGII_00695 4.4e-36 yqzF S Protein of unknown function (DUF2627)
OBOLLGII_00696 7.7e-132 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OBOLLGII_00697 4.4e-138 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OBOLLGII_00698 2.7e-233 rseP 3.4.21.116 M Stage IV sporulation protein B
OBOLLGII_00699 1.3e-291 recN L May be involved in recombinational repair of damaged DNA
OBOLLGII_00700 9.2e-80 argR K Regulates arginine biosynthesis genes
OBOLLGII_00701 8.5e-148 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
OBOLLGII_00702 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OBOLLGII_00703 2.9e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OBOLLGII_00704 3.1e-31 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OBOLLGII_00705 3.5e-228 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OBOLLGII_00706 1.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OBOLLGII_00707 1.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OBOLLGII_00708 1.1e-68 yqhY S protein conserved in bacteria
OBOLLGII_00709 1.8e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OBOLLGII_00710 6.8e-81 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OBOLLGII_00711 8.2e-67 spoIIIAH S SpoIIIAH-like protein
OBOLLGII_00712 6.6e-111 spoIIIAG S stage III sporulation protein AG
OBOLLGII_00713 1.8e-105 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
OBOLLGII_00714 1.7e-173 spoIIIAE S stage III sporulation protein AE
OBOLLGII_00715 2.3e-58 spoIIIAD S Stage III sporulation protein AD
OBOLLGII_00716 1.4e-27 spoIIIAC S stage III sporulation protein AC
OBOLLGII_00717 3.7e-85 spoIIIAB S Stage III sporulation protein
OBOLLGII_00718 8e-171 spoIIIAA S stage III sporulation protein AA
OBOLLGII_00719 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OBOLLGII_00720 5.4e-155 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OBOLLGII_00721 9.6e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
OBOLLGII_00722 3.1e-86 yqhR S Conserved membrane protein YqhR
OBOLLGII_00723 2.7e-163 yqhQ S Protein of unknown function (DUF1385)
OBOLLGII_00724 4.3e-11 yqhP
OBOLLGII_00725 5.6e-40 yqhO S esterase of the alpha-beta hydrolase superfamily
OBOLLGII_00726 4.2e-264 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00727 5.8e-113 yqhO S esterase of the alpha-beta hydrolase superfamily
OBOLLGII_00728 2.3e-71 bktB 2.3.1.9 I Belongs to the thiolase family
OBOLLGII_00729 0.0 nrdA 1.17.4.1 F Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
OBOLLGII_00730 6.8e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OBOLLGII_00731 2.2e-66 yqhL P COG0607 Rhodanese-related sulfurtransferase
OBOLLGII_00732 3.7e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OBOLLGII_00733 5.3e-256 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OBOLLGII_00734 5.4e-214 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
OBOLLGII_00735 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OBOLLGII_00736 2.7e-151 yqhG S Bacterial protein YqhG of unknown function
OBOLLGII_00737 2.3e-10 yqzE S YqzE-like protein
OBOLLGII_00738 3.8e-99 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OBOLLGII_00739 7.6e-56 S ComG operon protein 7
OBOLLGII_00740 2.9e-79 comGF U COG4940 Competence protein ComGF
OBOLLGII_00742 5.7e-74 gspH NU COG2165 Type II secretory pathway, pseudopilin PulG
OBOLLGII_00743 9.9e-49 comGC U Required for transformation and DNA binding
OBOLLGII_00744 3.7e-171 comGB NU COG1459 Type II secretory pathway, component PulF
OBOLLGII_00745 1.6e-202 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OBOLLGII_00746 1e-128 K Helix-turn-helix domain
OBOLLGII_00747 5.7e-36 yqgY S Protein of unknown function (DUF2626)
OBOLLGII_00748 5e-124 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OBOLLGII_00749 2.9e-21 yqgW S Protein of unknown function (DUF2759)
OBOLLGII_00750 1.6e-169 glcK 2.7.1.2 G Glucokinase
OBOLLGII_00751 2.8e-29 yqgQ S protein conserved in bacteria
OBOLLGII_00752 6.4e-202 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
OBOLLGII_00754 1.6e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OBOLLGII_00755 1.1e-54 yqzD
OBOLLGII_00756 0.0 mrdA 3.4.16.4 M penicillin-binding protein
OBOLLGII_00757 1.2e-219 yqgE EGP Major facilitator superfamily
OBOLLGII_00758 3.7e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
OBOLLGII_00759 4.4e-55 fimV NU Tfp pilus assembly protein FimV
OBOLLGII_00760 6.8e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OBOLLGII_00761 4.4e-114 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
OBOLLGII_00762 1.5e-74 zur P Belongs to the Fur family
OBOLLGII_00763 4e-140 znuB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OBOLLGII_00764 2.7e-140 zurA P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OBOLLGII_00765 1e-19 yqfT S Protein of unknown function (DUF2624)
OBOLLGII_00766 1.8e-126 cwlO CBM50 M protein conserved in bacteria
OBOLLGII_00767 1.5e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OBOLLGII_00768 7.2e-242 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OBOLLGII_00770 9.8e-180 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OBOLLGII_00771 8.4e-207 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OBOLLGII_00772 7.7e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
OBOLLGII_00773 1.4e-64 cccA C Cytochrome C oxidase, cbb3-type, subunit III
OBOLLGII_00774 6.4e-88
OBOLLGII_00775 2.8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OBOLLGII_00776 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OBOLLGII_00777 5.5e-144 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OBOLLGII_00778 2.2e-111 ccpN K CBS domain
OBOLLGII_00779 8.8e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00780 8.2e-145 recO L Involved in DNA repair and RecF pathway recombination
OBOLLGII_00781 8.7e-08 S YqzL-like protein
OBOLLGII_00782 5.6e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OBOLLGII_00783 7.9e-67 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OBOLLGII_00784 4.2e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OBOLLGII_00785 2e-163 yqfF S membrane-associated HD superfamily hydrolase
OBOLLGII_00786 5.4e-55 yqfF S membrane-associated HD superfamily hydrolase
OBOLLGII_00787 6.1e-174 phoH T Phosphate starvation-inducible protein PhoH
OBOLLGII_00788 3.6e-224 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
OBOLLGII_00789 3.2e-46 yqfC S sporulation protein YqfC
OBOLLGII_00790 6.6e-70 yqeY S Yqey-like protein
OBOLLGII_00791 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OBOLLGII_00792 2.2e-47 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OBOLLGII_00793 4.3e-156 yqeW P COG1283 Na phosphate symporter
OBOLLGII_00794 1.2e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
OBOLLGII_00795 2.7e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OBOLLGII_00796 1.9e-172 prmA J Methylates ribosomal protein L11
OBOLLGII_00797 1.6e-205 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OBOLLGII_00798 3.6e-308 dnaK O Heat shock 70 kDa protein
OBOLLGII_00799 1.4e-89 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OBOLLGII_00800 8.3e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OBOLLGII_00801 3.7e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
OBOLLGII_00802 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OBOLLGII_00803 2.9e-221 spoIIP M stage II sporulation protein P
OBOLLGII_00804 4.7e-202 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OBOLLGII_00805 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
OBOLLGII_00806 1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
OBOLLGII_00808 0.0 comEC S Competence protein ComEC
OBOLLGII_00809 2.1e-111 comEB 3.5.4.12 F COG2131 Deoxycytidylate deaminase
OBOLLGII_00810 8.8e-93 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
OBOLLGII_00811 1.1e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OBOLLGII_00812 2.5e-146 cmoA S Methyltransferase domain
OBOLLGII_00813 1.1e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OBOLLGII_00814 3.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OBOLLGII_00815 5e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OBOLLGII_00816 3.6e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
OBOLLGII_00817 4e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OBOLLGII_00818 2e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OBOLLGII_00819 9.9e-94 yqeG S hydrolase of the HAD superfamily
OBOLLGII_00820 2.8e-257 glcF C Glycolate oxidase
OBOLLGII_00821 7.7e-258 glcD 1.1.3.15 C Glycolate oxidase subunit
OBOLLGII_00822 1.6e-205 ysfB KT regulator
OBOLLGII_00823 4.3e-224 mco 1.16.3.3 Q multicopper oxidases
OBOLLGII_00824 9.6e-74 hsp18 O Belongs to the small heat shock protein (HSP20) family
OBOLLGII_00825 7.8e-22 S Short C-terminal domain
OBOLLGII_00826 2.1e-103 CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OBOLLGII_00827 1.3e-116 S TPM domain
OBOLLGII_00828 6.5e-78 lemA S LemA family
OBOLLGII_00829 4.3e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OBOLLGII_00830 1.2e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OBOLLGII_00831 9.1e-119 S VIT family
OBOLLGII_00832 5.1e-154 czcD P COG1230 Co Zn Cd efflux system component
OBOLLGII_00833 2.7e-14 sda S Sporulation inhibitor A
OBOLLGII_00834 4.8e-91 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OBOLLGII_00835 6.1e-126 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OBOLLGII_00836 6.2e-293 ahpF O Alkyl hydroperoxide reductase
OBOLLGII_00837 3.8e-107 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
OBOLLGII_00839 1.7e-10 S YrhC-like protein
OBOLLGII_00840 4.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OBOLLGII_00841 6.4e-28 yrzA S Protein of unknown function (DUF2536)
OBOLLGII_00842 7.9e-58 yrrS S Protein of unknown function (DUF1510)
OBOLLGII_00843 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OBOLLGII_00844 1.7e-111 udk 2.7.1.48 F Cytidine monophosphokinase
OBOLLGII_00845 7.4e-115 yrrM 2.1.1.104 S O-methyltransferase
OBOLLGII_00846 1.5e-203 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OBOLLGII_00847 1.5e-41 yrzB S Belongs to the UPF0473 family
OBOLLGII_00848 6.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OBOLLGII_00849 2.2e-44 yrzL S Belongs to the UPF0297 family
OBOLLGII_00850 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OBOLLGII_00851 3.8e-172 yrrI S AI-2E family transporter
OBOLLGII_00853 4e-29 yrzR
OBOLLGII_00854 8.2e-73 yndM S Protein of unknown function (DUF2512)
OBOLLGII_00855 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OBOLLGII_00856 1.3e-125 S COG0457 FOG TPR repeat
OBOLLGII_00857 9.8e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OBOLLGII_00858 2.6e-208 iscS 2.8.1.7 E Cysteine desulfurase
OBOLLGII_00859 2.3e-72 cymR K Transcriptional regulator
OBOLLGII_00860 8.5e-265 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00862 1.8e-17 gerLA EG Spore germination protein
OBOLLGII_00863 1.7e-72 S membrane transporter protein
OBOLLGII_00864 2.5e-25 yrkI O Sulfurtransferase TusA
OBOLLGII_00865 6.2e-157 yrkH P COG0607 Rhodanese-related sulfurtransferase
OBOLLGII_00866 2.1e-56 S DsrE/DsrF-like family
OBOLLGII_00867 1.7e-67 yrkF OP Belongs to the sulfur carrier protein TusA family
OBOLLGII_00868 3.7e-26 P Sulfurtransferase
OBOLLGII_00869 2.1e-28 yrkD S Metal-sensitive transcriptional repressor
OBOLLGII_00870 5.2e-39 3.2.1.23 S Domain of unknown function DUF302
OBOLLGII_00871 4.4e-42 Q ubiE/COQ5 methyltransferase family
OBOLLGII_00872 1.2e-15 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OBOLLGII_00873 9.4e-29 CO Thioredoxin-like
OBOLLGII_00874 1.2e-33 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
OBOLLGII_00875 1.9e-84 ccdA O Cytochrome C biogenesis protein transmembrane region
OBOLLGII_00876 4.9e-29 O OsmC-like protein
OBOLLGII_00877 3.6e-59 K Transcriptional regulator
OBOLLGII_00878 4.1e-73 yneN CO Thioredoxin-like
OBOLLGII_00879 7.3e-138 L SMART ATPase, AAA type, core
OBOLLGII_00880 3.6e-298 L PFAM Integrase, catalytic core
OBOLLGII_00881 6.2e-110 S Protein of unknown function (DUF4236)
OBOLLGII_00882 3.8e-265 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00883 8.8e-136 IQ Short-chain dehydrogenase reductase sdr
OBOLLGII_00884 3e-248 L PFAM Transposase, IS4-like
OBOLLGII_00885 2.8e-238 cshA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OBOLLGII_00886 4.1e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OBOLLGII_00887 6.5e-163 ybaS 1.1.1.58 S Na -dependent transporter
OBOLLGII_00889 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OBOLLGII_00890 7.8e-249 hisS 6.1.1.21 J histidyl-tRNA synthetase
OBOLLGII_00892 1.8e-273 lytH 3.5.1.28, 6.1.1.12 M COG3103 SH3 domain protein
OBOLLGII_00893 5.2e-307 yhcA5 EGP Major facilitator Superfamily
OBOLLGII_00894 1.4e-105 emrA V COG1566 Multidrug resistance efflux pump
OBOLLGII_00895 1.6e-68 K helix_turn_helix multiple antibiotic resistance protein
OBOLLGII_00896 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OBOLLGII_00897 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OBOLLGII_00898 5.3e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OBOLLGII_00899 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OBOLLGII_00900 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OBOLLGII_00901 3.6e-60 yrzD S Post-transcriptional regulator
OBOLLGII_00902 1.9e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OBOLLGII_00903 6e-104 yrbG S membrane
OBOLLGII_00904 4.9e-61 yrzE S Protein of unknown function (DUF3792)
OBOLLGII_00905 1.2e-44 yajC U Preprotein translocase subunit YajC
OBOLLGII_00906 6.9e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OBOLLGII_00907 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OBOLLGII_00908 5.4e-27 yrzS S Protein of unknown function (DUF2905)
OBOLLGII_00909 2.3e-184 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OBOLLGII_00910 1.7e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OBOLLGII_00911 1.7e-128 yebC K transcriptional regulatory protein
OBOLLGII_00912 2.3e-189 1.1.1.34, 2.7.1.89 M choline kinase involved in LPS biosynthesis
OBOLLGII_00913 3.4e-140 safA M spore coat assembly protein SafA
OBOLLGII_00914 3.5e-97 niaR S small molecule binding protein (contains 3H domain)
OBOLLGII_00915 7.8e-157 pheA 4.2.1.51 E Prephenate dehydratase
OBOLLGII_00916 1.2e-74 pheB 5.4.99.5 S Belongs to the UPF0735 family
OBOLLGII_00917 3.4e-244 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OBOLLGII_00918 7.5e-97 spo0B T Sporulation initiation phospho-transferase B, C-terminal
OBOLLGII_00919 1.1e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OBOLLGII_00920 4.6e-52 ysxB J ribosomal protein
OBOLLGII_00921 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
OBOLLGII_00922 1.8e-260 rng J ribonuclease, Rne Rng family
OBOLLGII_00923 4.3e-158 spoIVFB S Stage IV sporulation protein
OBOLLGII_00924 1.4e-133 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
OBOLLGII_00925 2.5e-144 minD D Belongs to the ParA family
OBOLLGII_00926 1.4e-119 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OBOLLGII_00927 9e-87 mreD M shape-determining protein
OBOLLGII_00928 5.3e-140 mreC M Involved in formation and maintenance of cell shape
OBOLLGII_00929 1.1e-184 mreB D Rod shape-determining protein MreB
OBOLLGII_00930 1.1e-37 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00931 9.5e-217 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00932 6.9e-100 radC E Belongs to the UPF0758 family
OBOLLGII_00933 1.1e-165 spoIIB
OBOLLGII_00934 3.8e-142 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OBOLLGII_00935 1.2e-97
OBOLLGII_00936 2.3e-81 pilN NU PFAM Fimbrial assembly family protein
OBOLLGII_00937 1.6e-180 NU COG4972 Tfp pilus assembly protein, ATPase PilM
OBOLLGII_00938 1.2e-16 NU cell adhesion
OBOLLGII_00939 1.9e-201 pilC NU type II secretion system
OBOLLGII_00940 1.3e-193 pilT NU twitching motility protein
OBOLLGII_00941 5.8e-289 pilB NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OBOLLGII_00942 1.1e-195 V G5
OBOLLGII_00943 5.1e-120 S PRC-barrel domain
OBOLLGII_00944 2.9e-145
OBOLLGII_00945 6.1e-263 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_00946 5.6e-207 NU Pilus assembly protein PilX
OBOLLGII_00947 1.8e-76
OBOLLGII_00949 2.3e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OBOLLGII_00950 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OBOLLGII_00951 3e-27
OBOLLGII_00952 1.7e-190 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OBOLLGII_00953 2e-200 spoVID M stage VI sporulation protein D
OBOLLGII_00954 3.5e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OBOLLGII_00955 7.1e-186 hemB 4.2.1.24 H Belongs to the ALAD family
OBOLLGII_00956 1.9e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OBOLLGII_00957 3e-165 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OBOLLGII_00958 1.7e-148 hemX O cytochrome C
OBOLLGII_00959 2.1e-241 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OBOLLGII_00960 2.2e-87 ysxD
OBOLLGII_00961 1.3e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
OBOLLGII_00962 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OBOLLGII_00963 1.5e-308 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
OBOLLGII_00964 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OBOLLGII_00965 8.4e-211 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OBOLLGII_00966 6.8e-184 trxA2 O COG0457 FOG TPR repeat
OBOLLGII_00967 5.9e-71 S Protein of unknown function (DUF2512)
OBOLLGII_00968 1.5e-46
OBOLLGII_00970 7e-92 ysnB S Phosphoesterase
OBOLLGII_00971 6.6e-105 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OBOLLGII_00972 1.5e-189 gerM S COG5401 Spore germination protein
OBOLLGII_00974 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OBOLLGII_00975 3.9e-78 ysmB 2.4.2.28 K transcriptional
OBOLLGII_00976 3e-79 S GDYXXLXY protein
OBOLLGII_00978 1.4e-105 S HTH-like domain
OBOLLGII_00979 1.3e-23 ymbI L Transposase
OBOLLGII_00980 5.8e-166 L Transposase
OBOLLGII_00981 1.1e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_00982 2.3e-31 gerE K Transcriptional regulator
OBOLLGII_00983 6.7e-89 ysmA S thioesterase
OBOLLGII_00984 6.5e-150 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OBOLLGII_00985 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OBOLLGII_00986 2.5e-104 sdhC C succinate dehydrogenase
OBOLLGII_00987 3e-78 yslB S Protein of unknown function (DUF2507)
OBOLLGII_00988 2e-222 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OBOLLGII_00989 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OBOLLGII_00990 5.1e-53 trxA O Belongs to the thioredoxin family
OBOLLGII_00991 7.4e-175 etfA C Electron transfer flavoprotein
OBOLLGII_00992 4.8e-129 etfB C Electron transfer flavoprotein
OBOLLGII_00993 1.5e-138 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OBOLLGII_00994 6e-103 fadR K Transcriptional regulator
OBOLLGII_00995 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OBOLLGII_00996 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OBOLLGII_00997 0.0 polX L COG1796 DNA polymerase IV (family X)
OBOLLGII_00998 1.9e-87 cvpA S membrane protein, required for colicin V production
OBOLLGII_00999 7.3e-46 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OBOLLGII_01000 9.9e-169 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OBOLLGII_01001 5.7e-45 KT Transcriptional
OBOLLGII_01002 1.2e-31 V Mate efflux family protein
OBOLLGII_01003 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OBOLLGII_01004 9.6e-181 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OBOLLGII_01005 8.9e-136 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OBOLLGII_01006 6.4e-31 sspI S Belongs to the SspI family
OBOLLGII_01007 2.2e-134
OBOLLGII_01008 2.5e-29 sidE D nuclear chromosome segregation
OBOLLGII_01009 1.3e-23 ymbI L Transposase
OBOLLGII_01010 2.4e-105 S HTH-like domain
OBOLLGII_01011 1.5e-63 M1-1017 S Protein of unknown function (DUF1129)
OBOLLGII_01012 1.8e-56 K Transcriptional regulator
OBOLLGII_01013 2.3e-11 S NADPH-dependent FMN reductase
OBOLLGII_01014 1.3e-127 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OBOLLGII_01015 1.5e-177 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OBOLLGII_01016 2.3e-101 yieF S NAD(P)H-dependent FMN reductase
OBOLLGII_01017 4.3e-97 ypdE 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OBOLLGII_01018 9.6e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
OBOLLGII_01020 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OBOLLGII_01021 3.4e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OBOLLGII_01022 1e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OBOLLGII_01023 4.5e-220 G Transmembrane secretion effector
OBOLLGII_01024 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OBOLLGII_01025 8.3e-151 ytxC S YtxC-like family
OBOLLGII_01026 8.4e-176 dnaI L Primosomal protein DnaI
OBOLLGII_01027 2.1e-260 dnaB L Membrane attachment protein
OBOLLGII_01028 2.1e-79 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OBOLLGII_01029 3.2e-86 2.3.1.178 J Benzoate transporter
OBOLLGII_01030 1.2e-191 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OBOLLGII_01031 3.6e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OBOLLGII_01032 2.4e-105 ytaF P Probably functions as a manganese efflux pump
OBOLLGII_01033 8.5e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OBOLLGII_01034 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OBOLLGII_01035 3e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01036 2.9e-168 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
OBOLLGII_01037 4e-245 icd 1.1.1.42 C isocitrate
OBOLLGII_01038 4.1e-206 citZ 2.3.3.1 C Belongs to the citrate synthase family
OBOLLGII_01039 1e-73 yeaL S Membrane
OBOLLGII_01040 1e-156 ytvI S sporulation integral membrane protein YtvI
OBOLLGII_01041 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OBOLLGII_01042 4.1e-178 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OBOLLGII_01043 4.6e-177 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OBOLLGII_01044 1.1e-164 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OBOLLGII_01045 6.8e-226 ytsJ 1.1.1.38 C Malate dehydrogenase
OBOLLGII_01046 0.0 dnaE 2.7.7.7 L DNA polymerase
OBOLLGII_01047 1.6e-41 ytrH S Sporulation protein YtrH
OBOLLGII_01048 7.9e-88 ytrI
OBOLLGII_01049 9.1e-176 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
OBOLLGII_01050 7.1e-39 ytpI S YtpI-like protein
OBOLLGII_01051 2.3e-240 ytoI K transcriptional regulator containing CBS domains
OBOLLGII_01052 1.1e-129 ytkL S Belongs to the UPF0173 family
OBOLLGII_01053 1.6e-178 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OBOLLGII_01054 7.8e-197 ald 1.4.1.1 E Belongs to the AlaDH PNT family
OBOLLGII_01055 3.1e-78 uspA T Belongs to the universal stress protein A family
OBOLLGII_01056 3.1e-150 S EcsC protein family
OBOLLGII_01057 3e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OBOLLGII_01058 2.4e-176 ytxK 2.1.1.72 L DNA methylase
OBOLLGII_01059 2.2e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OBOLLGII_01060 2e-66 ytfJ S Sporulation protein YtfJ
OBOLLGII_01061 3.9e-119 ytfI S Protein of unknown function (DUF2953)
OBOLLGII_01062 4.2e-84 yteJ S RDD family
OBOLLGII_01063 6.7e-179 sppA OU signal peptide peptidase SppA
OBOLLGII_01064 2.2e-311 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OBOLLGII_01065 1.4e-27 sspB S spore protein
OBOLLGII_01066 1.9e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OBOLLGII_01067 5.2e-212 iscS2 2.8.1.7 E Cysteine desulfurase
OBOLLGII_01068 1.6e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OBOLLGII_01069 1.3e-116 yttP K Transcriptional regulator
OBOLLGII_01070 7e-86 ytsP 1.8.4.14 T GAF domain-containing protein
OBOLLGII_01071 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
OBOLLGII_01072 1.9e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OBOLLGII_01073 1.3e-145
OBOLLGII_01074 2e-126
OBOLLGII_01075 5.4e-181 putA E Proline dehydrogenase
OBOLLGII_01076 1.1e-297 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OBOLLGII_01077 4.5e-255 prdR KT Transcriptional regulator
OBOLLGII_01078 2.2e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OBOLLGII_01079 3.3e-152 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OBOLLGII_01080 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OBOLLGII_01081 5.7e-89 yrhD S Protein of unknown function (DUF1641)
OBOLLGII_01082 4e-192 moeB 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OBOLLGII_01083 1e-84 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OBOLLGII_01084 1.1e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OBOLLGII_01085 1.2e-79 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
OBOLLGII_01086 1.6e-85 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
OBOLLGII_01087 1.4e-234 moeA 2.10.1.1 H molybdopterin
OBOLLGII_01088 7.8e-123 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OBOLLGII_01089 1.4e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
OBOLLGII_01090 7.8e-188 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OBOLLGII_01091 1.5e-129 modC 3.6.3.29 P ATPases associated with a variety of cellular activities
OBOLLGII_01092 6.5e-120 P COG4149 ABC-type molybdate transport system, permease component
OBOLLGII_01093 1.5e-133 modA P Molybdenum ABC transporter
OBOLLGII_01094 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OBOLLGII_01095 2.5e-123 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OBOLLGII_01096 3.8e-119 acuB S Acetoin utilization protein AcuB
OBOLLGII_01097 1.6e-232 acuC BQ histone deacetylase
OBOLLGII_01098 1.7e-182 ccpA K catabolite control protein A
OBOLLGII_01099 1.4e-190 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OBOLLGII_01100 1.7e-34 XK27_07760 S COG4980 Gas vesicle protein
OBOLLGII_01101 2.5e-44 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OBOLLGII_01102 2.2e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OBOLLGII_01103 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OBOLLGII_01104 4.6e-71 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OBOLLGII_01105 5.2e-110 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OBOLLGII_01106 4.8e-148 ytpQ S Belongs to the UPF0354 family
OBOLLGII_01107 1.9e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OBOLLGII_01108 7.5e-195 rsbU 3.1.3.3 T response regulator
OBOLLGII_01109 8.9e-153 cheR 2.1.1.80 NT chemotaxis
OBOLLGII_01110 0.0 T PhoQ Sensor
OBOLLGII_01111 6.6e-53 ytzB S small secreted protein
OBOLLGII_01112 1.6e-170 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
OBOLLGII_01114 3e-127 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OBOLLGII_01115 1e-54 ytzH S YtzH-like protein
OBOLLGII_01116 4.8e-156 ytmP 2.7.1.89 M Phosphotransferase
OBOLLGII_01118 3.8e-144 ytlQ
OBOLLGII_01119 2.3e-104 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OBOLLGII_01121 2.3e-159 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OBOLLGII_01122 1.7e-273 pepV 3.5.1.18 E Dipeptidase
OBOLLGII_01123 1.2e-32 ytzE K COG1349 Transcriptional regulators of sugar metabolism
OBOLLGII_01124 1.2e-286 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OBOLLGII_01125 6.4e-27 yteV S Sporulation protein Cse60
OBOLLGII_01126 5e-10
OBOLLGII_01128 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OBOLLGII_01129 1.6e-187 yttB EGP Major facilitator Superfamily
OBOLLGII_01130 9.4e-43 ytzC S Protein of unknown function (DUF2524)
OBOLLGII_01132 2.9e-102 ytqB J Putative rRNA methylase
OBOLLGII_01133 5.7e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
OBOLLGII_01134 4.5e-154 ytpA 3.1.1.5 I Alpha beta hydrolase
OBOLLGII_01135 7.3e-73 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OBOLLGII_01136 0.0 asnB 6.3.5.4 E Asparagine synthase
OBOLLGII_01137 3.2e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OBOLLGII_01138 5.3e-308 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OBOLLGII_01139 2e-67 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
OBOLLGII_01140 2.5e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_01141 3.2e-206 L Transposase
OBOLLGII_01142 1.9e-208 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OBOLLGII_01143 2.3e-101 ywqN S NAD(P)H-dependent
OBOLLGII_01144 8.4e-54 gntK 2.7.1.12, 2.7.1.17 G FGGY family of carbohydrate kinases, N-terminal domain
OBOLLGII_01145 5.6e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OBOLLGII_01146 2.3e-139 ytlC P ABC transporter
OBOLLGII_01147 1.2e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OBOLLGII_01148 9.8e-85 ytkD 3.6.1.55 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OBOLLGII_01149 7.4e-39
OBOLLGII_01150 3.6e-76 dps P Belongs to the Dps family
OBOLLGII_01151 6.4e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
OBOLLGII_01153 3.4e-158 adcA P Belongs to the bacterial solute-binding protein 9 family
OBOLLGII_01154 4.8e-23 S Domain of Unknown Function (DUF1540)
OBOLLGII_01155 4.7e-210 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OBOLLGII_01156 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OBOLLGII_01157 1.9e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OBOLLGII_01158 7.7e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OBOLLGII_01159 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OBOLLGII_01160 7.9e-252 menF 5.4.4.2 HQ Isochorismate synthase
OBOLLGII_01161 9.4e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
OBOLLGII_01171 3e-09
OBOLLGII_01177 5.1e-08
OBOLLGII_01182 4.3e-42 S COG NOG14552 non supervised orthologous group
OBOLLGII_01183 4.4e-29 K Helix-turn-helix XRE-family like proteins
OBOLLGII_01185 9.2e-233 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
OBOLLGII_01186 2.2e-26
OBOLLGII_01187 3.4e-150 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OBOLLGII_01188 9.3e-116 sapB S MgtC SapB transporter
OBOLLGII_01189 1.2e-165 S Protein of unknown function (DUF1646)
OBOLLGII_01190 7.3e-30 EGP Major facilitator Superfamily
OBOLLGII_01191 0.0 copA 3.6.3.54 P P-type ATPase
OBOLLGII_01192 4e-30 P Copper resistance protein CopZ
OBOLLGII_01193 8.4e-57 S protein conserved in bacteria
OBOLLGII_01194 2.5e-68 lrpC K Transcriptional regulator
OBOLLGII_01195 8.6e-72 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OBOLLGII_01197 5.5e-225 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OBOLLGII_01198 1.3e-27 yhjC S Protein of unknown function (DUF3311)
OBOLLGII_01199 1.2e-266 E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OBOLLGII_01200 6.1e-263 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01203 9.1e-33 S Protein of unknown function (DUF2933)
OBOLLGII_01205 3.2e-248 T PhoQ Sensor
OBOLLGII_01206 1.5e-126 KT COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OBOLLGII_01207 4.9e-91 ydhK M Protein of unknown function (DUF1541)
OBOLLGII_01208 5.2e-93 VY92_08700 S Enoyl-(Acyl carrier protein) reductase
OBOLLGII_01209 4.1e-12 recN L Putative cell-wall binding lipoprotein
OBOLLGII_01210 2.7e-174 nodB1 G deacetylase
OBOLLGII_01211 7.7e-150 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01215 1.8e-240 P Voltage gated chloride channel
OBOLLGII_01216 9.4e-49 P Rhodanese domain protein
OBOLLGII_01217 2.8e-36 yhjE S protein conserved in bacteria
OBOLLGII_01218 3e-142 yokF 3.1.31.1 L RNA catabolic process
OBOLLGII_01219 4e-71 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
OBOLLGII_01220 1.3e-218 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01221 1.3e-23 ymbI L Transposase
OBOLLGII_01222 1.4e-105 S HTH-like domain
OBOLLGII_01223 1.3e-36 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01224 2.8e-210 L Transposase
OBOLLGII_01225 8.1e-132 IQ Enoyl-(Acyl carrier protein) reductase
OBOLLGII_01226 9.6e-72 yuiD S protein conserved in bacteria
OBOLLGII_01227 2.1e-221 solA 1.5.3.1 E FAD dependent oxidoreductase
OBOLLGII_01228 1.3e-226 FOXRED 1.5.3.1 E FAD dependent oxidoreductase
OBOLLGII_01229 6.5e-276 ycbD 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OBOLLGII_01230 5.8e-169 4.3.1.12 E ornithine cyclodeaminase
OBOLLGII_01233 1.9e-181 yugO P COG1226 Kef-type K transport systems
OBOLLGII_01234 1.3e-259 pgi 5.3.1.9 G Belongs to the GPI family
OBOLLGII_01235 3.3e-33 yuzA S Domain of unknown function (DUF378)
OBOLLGII_01236 4e-86 K Bacterial transcription activator, effector binding domain
OBOLLGII_01237 1.2e-64 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
OBOLLGII_01238 5.9e-29 K Helix-turn-helix XRE-family like proteins
OBOLLGII_01239 1.6e-196 namA C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OBOLLGII_01240 1e-164 S reductase
OBOLLGII_01241 2.4e-158 dkgB S Aldo/keto reductase family
OBOLLGII_01242 3e-237 S protein conserved in bacteria
OBOLLGII_01244 2.7e-111 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OBOLLGII_01245 8.4e-19 S Domain of unknown function (DUF4391)
OBOLLGII_01246 3.5e-268 L Transposase
OBOLLGII_01247 4e-297 L PFAM Integrase, catalytic core
OBOLLGII_01248 7.3e-138 L SMART ATPase, AAA type, core
OBOLLGII_01249 2.9e-251 L PFAM transposase IS4 family protein
OBOLLGII_01250 9.6e-195 mod 2.1.1.72 L DNA methylase
OBOLLGII_01251 0.0 res 3.1.21.5 V Type III restriction enzyme, res subunit
OBOLLGII_01252 3e-194 yuxJ EGP Major facilitator Superfamily
OBOLLGII_01253 9.4e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
OBOLLGII_01254 2.8e-55 yuzC
OBOLLGII_01256 1e-191 E Spore germination protein
OBOLLGII_01257 9.3e-228 gerKC S spore germination
OBOLLGII_01258 2.6e-297 gerKA EG Spore germination protein
OBOLLGII_01260 1.4e-298 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OBOLLGII_01261 1.9e-107 yuiC S protein conserved in bacteria
OBOLLGII_01262 1.2e-46 yuiB S Putative membrane protein
OBOLLGII_01263 1.4e-228 yumB 1.6.99.3 C NADH dehydrogenase
OBOLLGII_01264 6.1e-185 yumC 1.18.1.2, 1.19.1.1 C reductase
OBOLLGII_01265 9.5e-173 icaC G transferase activity, transferring acyl groups other than amino-acyl groups
OBOLLGII_01266 8.4e-148 icaB G Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl- D-glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide
OBOLLGII_01267 1.1e-47 icaD
OBOLLGII_01268 7.9e-233 pgaC GT2 M N-acetylglucosaminyltransferase that catalyzes the polymerization of single monomer units of UDP-N-acetylglucosamine to produce the linear homopolymer poly-beta-1,6-N-acetyl-D- glucosamine (PNAG, also referred to as PIA), a biofilm adhesin polysaccharide. Requires IcaD for full activity
OBOLLGII_01270 9.7e-154 L COG2801 Transposase and inactivated derivatives
OBOLLGII_01271 2.3e-209 L Transposase
OBOLLGII_01272 1.1e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_01273 2.2e-63 erpA S Belongs to the HesB IscA family
OBOLLGII_01274 1.1e-59 yuzD S protein conserved in bacteria
OBOLLGII_01275 1.3e-23 ymbI L Transposase
OBOLLGII_01276 3e-96 S HTH-like domain
OBOLLGII_01277 5.2e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01278 8.6e-37 nifU O COG0694 Thioredoxin-like proteins and domains
OBOLLGII_01279 5.8e-199 yutH S Spore coat protein
OBOLLGII_01280 4.8e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OBOLLGII_01281 3.3e-07 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OBOLLGII_01282 3.3e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OBOLLGII_01283 4.3e-74 yutE S Protein of unknown function DUF86
OBOLLGII_01284 2.6e-48 yutD S protein conserved in bacteria
OBOLLGII_01285 1e-173 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OBOLLGII_01286 6.7e-200 lytH M Peptidase, M23
OBOLLGII_01287 9.4e-127 yunB S Sporulation protein YunB (Spo_YunB)
OBOLLGII_01288 3.7e-48 yunC S Domain of unknown function (DUF1805)
OBOLLGII_01289 2.6e-277 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OBOLLGII_01290 2.2e-273 sufB O FeS cluster assembly
OBOLLGII_01291 9.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
OBOLLGII_01292 1.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OBOLLGII_01293 4.2e-242 sufD O assembly protein SufD
OBOLLGII_01294 1.7e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OBOLLGII_01296 1.5e-49 traF CO Thioredoxin
OBOLLGII_01297 5.1e-63 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OBOLLGII_01298 3.1e-62 arsC 1.20.4.1 P Belongs to the ArsC family
OBOLLGII_01299 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
OBOLLGII_01300 3.9e-215 fadA 2.3.1.16 I Belongs to the thiolase family
OBOLLGII_01301 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
OBOLLGII_01302 2.6e-14 S YuzL-like protein
OBOLLGII_01303 2.4e-40
OBOLLGII_01304 7.1e-56 yusN M Coat F domain
OBOLLGII_01305 1.3e-213 rodA D Belongs to the SEDS family
OBOLLGII_01306 5.7e-70 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OBOLLGII_01308 1.8e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01309 2.7e-171 tnp4 L Transposase, Mutator family
OBOLLGII_01310 2.3e-281 cls2 I PLD-like domain
OBOLLGII_01312 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OBOLLGII_01313 1.5e-189 M1-600 T Putative diguanylate phosphodiesterase
OBOLLGII_01314 3.1e-297 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OBOLLGII_01315 3.5e-100 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OBOLLGII_01316 2.9e-139 pgdA 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
OBOLLGII_01317 1.3e-240 ugtP 2.4.1.315 GT28 M Monogalactosyldiacylglycerol (MGDG) synthase
OBOLLGII_01318 4.9e-122
OBOLLGII_01319 1.5e-83 S Putative zinc-finger
OBOLLGII_01320 1.3e-88 K Belongs to the sigma-70 factor family. ECF subfamily
OBOLLGII_01321 6.9e-220 ykoN 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
OBOLLGII_01322 0.0 M Dolichyl-phosphate-mannose-protein mannosyltransferase
OBOLLGII_01323 7.4e-243 NU cell adhesion
OBOLLGII_01324 1.1e-186 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OBOLLGII_01325 6.4e-179 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
OBOLLGII_01326 9.5e-163 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OBOLLGII_01327 1.4e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OBOLLGII_01328 4.9e-260 yjmB G MFS/sugar transport protein
OBOLLGII_01329 9e-283 uxaC 5.3.1.12 G glucuronate isomerase
OBOLLGII_01330 1.5e-283 uxaA 4.2.1.7, 4.4.1.24 G Altronate
OBOLLGII_01331 5.6e-272 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
OBOLLGII_01332 3.2e-189 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
OBOLLGII_01333 4e-119 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
OBOLLGII_01334 1.1e-136 K helix_turn_helix isocitrate lyase regulation
OBOLLGII_01335 7e-53 S SMI1 / KNR4 family (SUKH-1)
OBOLLGII_01336 2.9e-39
OBOLLGII_01337 6e-280 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OBOLLGII_01339 8.4e-196 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01340 1.1e-22
OBOLLGII_01341 1.3e-23 ymbI L Transposase
OBOLLGII_01342 9.3e-105 S HTH-like domain
OBOLLGII_01343 8.7e-42 L COG4584 Transposase and inactivated derivatives
OBOLLGII_01344 1.3e-126 U COG3267 Type II secretory pathway, component ExeA
OBOLLGII_01345 2.7e-231 L Mu transposase, C-terminal
OBOLLGII_01347 4.9e-157 L PFAM Integrase catalytic
OBOLLGII_01348 1.9e-111 L Bacterial dnaA protein
OBOLLGII_01349 2.6e-49 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01350 9.7e-19
OBOLLGII_01351 6.3e-09 S transposase or invertase
OBOLLGII_01352 5e-81 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OBOLLGII_01353 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OBOLLGII_01354 3.4e-143 est 3.1.1.1 S Carboxylesterase
OBOLLGII_01355 4.2e-28 secG U Preprotein translocase subunit SecG
OBOLLGII_01356 1.3e-240 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OBOLLGII_01358 2.3e-300 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
OBOLLGII_01359 1.1e-122 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OBOLLGII_01360 5.9e-219 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OBOLLGII_01361 9.9e-183 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OBOLLGII_01362 2.2e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OBOLLGII_01363 2.3e-39 XAC3035 O Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OBOLLGII_01364 1.2e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OBOLLGII_01365 8.5e-265 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01367 1.3e-07 S Heavy-metal-associated domain
OBOLLGII_01368 4.5e-56 S Protein of unknown function (DUF1641)
OBOLLGII_01370 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OBOLLGII_01371 1.7e-31
OBOLLGII_01373 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OBOLLGII_01374 6.2e-85 uspF T Universal stress protein
OBOLLGII_01376 3.4e-191 ykfD E Belongs to the ABC transporter superfamily
OBOLLGII_01377 3.6e-176 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OBOLLGII_01378 0.0 dppE E ABC transporter substrate-binding protein
OBOLLGII_01379 9.3e-189 dppD P Belongs to the ABC transporter superfamily
OBOLLGII_01380 4.1e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OBOLLGII_01381 4.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OBOLLGII_01382 9.2e-127 S Peptidase C26
OBOLLGII_01383 2.5e-183 corA P Mediates influx of magnesium ions
OBOLLGII_01384 1.8e-46 yhdB S YhdB-like protein
OBOLLGII_01386 1.5e-274 ycgB S Stage V sporulation protein R
OBOLLGII_01387 4.1e-181 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
OBOLLGII_01388 1.6e-134 3.2.1.18 GH33 E GDSL-like Lipase/Acylhydrolase
OBOLLGII_01389 2.1e-73 bdbC O Required for disulfide bond formation in some proteins
OBOLLGII_01390 5.8e-88 bdbA CO Thioredoxin
OBOLLGII_01391 3.9e-66 yhcU S Family of unknown function (DUF5365)
OBOLLGII_01392 1.2e-10 yhcU S Family of unknown function (DUF5365)
OBOLLGII_01393 5.6e-112 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
OBOLLGII_01394 3.4e-175 pit P phosphate transporter
OBOLLGII_01395 1.9e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
OBOLLGII_01397 5.3e-220 yhbH S Belongs to the UPF0229 family
OBOLLGII_01398 0.0 prkA T Ser protein kinase
OBOLLGII_01399 2e-88 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OBOLLGII_01400 1.1e-161 yhbB S Putative amidase domain
OBOLLGII_01401 6e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OBOLLGII_01402 8.2e-103 yvbG U UPF0056 membrane protein
OBOLLGII_01403 1.6e-166 ppaC 3.6.1.1 C Inorganic pyrophosphatase
OBOLLGII_01404 2.4e-83 S Rubrerythrin
OBOLLGII_01405 1.4e-144 tcyA ET Belongs to the bacterial solute-binding protein 3 family
OBOLLGII_01406 1.2e-115 tcyB P COG0765 ABC-type amino acid transport system, permease component
OBOLLGII_01407 2.1e-66 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OBOLLGII_01408 1.8e-22 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OBOLLGII_01409 3.5e-149 focA P Formate/nitrite transporter
OBOLLGII_01412 0.0 pflB 2.3.1.54 C formate acetyltransferase
OBOLLGII_01413 2.1e-145 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OBOLLGII_01414 1.1e-95 1.5.1.38 S FMN reductase
OBOLLGII_01415 6.4e-88
OBOLLGII_01416 1.6e-174 bcrB S ABC transporter (permease)
OBOLLGII_01417 5.6e-169 bcrA V ABC transporter, ATP-binding protein
OBOLLGII_01418 6.3e-132 ypmR1 E G-D-S-L family
OBOLLGII_01419 1.9e-53 P Domain of unknown function (DUF2935)
OBOLLGII_01421 8.5e-265 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01422 1.7e-190 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OBOLLGII_01423 1.1e-198 adhC 1.1.1.1 C Zinc-binding dehydrogenase
OBOLLGII_01426 1.6e-08
OBOLLGII_01430 8.7e-08
OBOLLGII_01431 1.7e-07
OBOLLGII_01439 5.3e-43
OBOLLGII_01440 4.3e-42 S COG NOG14552 non supervised orthologous group
OBOLLGII_01441 3.4e-163 ygxA S Nucleotidyltransferase-like
OBOLLGII_01442 5e-57 ygzB S UPF0295 protein
OBOLLGII_01443 2.9e-139 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
OBOLLGII_01444 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OBOLLGII_01445 1.5e-163 alsR K Transcriptional regulator
OBOLLGII_01446 5.4e-87 iprA K Transcriptional regulator
OBOLLGII_01448 2.9e-81 perR P Belongs to the Fur family
OBOLLGII_01449 2.3e-101 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Adenosyltransferase
OBOLLGII_01451 3.4e-65 P Ion transport
OBOLLGII_01452 1.1e-247 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OBOLLGII_01453 7e-38 yqhV S Protein of unknown function (DUF2619)
OBOLLGII_01454 3.2e-187 ygaE S Membrane
OBOLLGII_01455 2.6e-147 K transcriptional
OBOLLGII_01456 6.2e-250 sacX 2.7.1.201, 2.7.1.211 G phosphotransferase system
OBOLLGII_01457 1.7e-149 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OBOLLGII_01458 1.8e-206 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
OBOLLGII_01459 2.4e-250 L PFAM transposase IS4 family protein
OBOLLGII_01460 0.0 ygaD V ABC transporter
OBOLLGII_01461 4.1e-103 ygaC J Belongs to the UPF0374 family
OBOLLGII_01462 1.3e-35 ygaB S YgaB-like protein
OBOLLGII_01463 1.7e-08 sspE S Small, acid-soluble spore protein, gamma-type
OBOLLGII_01464 7.7e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OBOLLGII_01465 1.7e-165 gltC K Transcriptional regulator
OBOLLGII_01466 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
OBOLLGII_01468 6.1e-282 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OBOLLGII_01469 8.8e-31
OBOLLGII_01470 3.1e-198 mutY L A G-specific
OBOLLGII_01471 2.9e-179 yfhP S membrane-bound metal-dependent
OBOLLGII_01472 4.2e-19 sspK S reproduction
OBOLLGII_01473 3.5e-49 yfhH S Protein of unknown function (DUF1811)
OBOLLGII_01474 1.8e-131 recX 2.4.1.337 GT4 S Modulates RecA activity
OBOLLGII_01476 3.2e-24 yfhD S YfhD-like protein
OBOLLGII_01477 6.9e-139 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OBOLLGII_01479 1.6e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OBOLLGII_01480 1.2e-245 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpC family
OBOLLGII_01481 1.1e-181 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OBOLLGII_01482 5.3e-107 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
OBOLLGII_01483 9.5e-261 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OBOLLGII_01484 3.8e-48 bacI V COG0577 ABC-type antimicrobial peptide transport system, permease component
OBOLLGII_01485 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
OBOLLGII_01487 7e-241 mcpA NT chemotaxis protein
OBOLLGII_01488 2.8e-182 serA1 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OBOLLGII_01489 4e-220 dhsS 1.12.1.2 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OBOLLGII_01490 1e-301 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OBOLLGII_01491 1.5e-178 S Phosphotransferase system, EIIC
OBOLLGII_01492 3.3e-219 2.6.1.9 S HAD-hyrolase-like
OBOLLGII_01493 7.4e-189 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OBOLLGII_01494 7.8e-111 leuD 4.2.1.33, 4.2.1.35, 4.2.1.36 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OBOLLGII_01495 9.7e-269 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OBOLLGII_01496 1.7e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OBOLLGII_01497 1.3e-282 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OBOLLGII_01498 1.8e-195 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OBOLLGII_01499 1.1e-84 ilvN 2.2.1.6 E Acetolactate synthase
OBOLLGII_01500 0.0 ilvB 2.2.1.6 E Acetolactate synthase
OBOLLGII_01501 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OBOLLGII_01502 4.6e-244 braB E Component of the transport system for branched-chain amino acids
OBOLLGII_01503 3.8e-151 T STAS domain
OBOLLGII_01504 4.6e-246
OBOLLGII_01505 2.1e-37 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
OBOLLGII_01506 2.6e-104 yetJ S Belongs to the BI1 family
OBOLLGII_01507 7e-214 yxjG 2.1.1.14 E Methionine synthase
OBOLLGII_01508 2.3e-218 yhjX P Major facilitator superfamily
OBOLLGII_01509 2.1e-137 ypdB KT LytTr DNA-binding domain
OBOLLGII_01510 7.5e-308 ypdA 2.7.13.3 T Signal transduction histidine kinase
OBOLLGII_01511 3.6e-193 ansA 3.5.1.1 EJ L-asparaginase
OBOLLGII_01512 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OBOLLGII_01513 3.8e-20 yhgD K Transcriptional regulator
OBOLLGII_01514 2.3e-54 yhgE S YhgE Pip N-terminal domain protein
OBOLLGII_01515 6.6e-248 S Protein of unknown function N-terminus (DUF3323)
OBOLLGII_01516 0.0 D Putative exonuclease SbcCD, C subunit
OBOLLGII_01517 6.8e-85 D Putative exonuclease SbcCD, C subunit
OBOLLGII_01518 2.4e-228 S Protein of unknown function (DUF2398)
OBOLLGII_01520 8.6e-260 S Protein of unknown function (DUF2397)
OBOLLGII_01521 1.6e-13 yoaT S Protein of unknown function (DUF817)
OBOLLGII_01522 5.1e-28 yozG K Transcriptional regulator
OBOLLGII_01523 1.6e-69 yoaS S Protein of unknown function (DUF2975)
OBOLLGII_01524 4.2e-43
OBOLLGII_01525 5.6e-237 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OBOLLGII_01526 8.6e-76 yqgC S protein conserved in bacteria
OBOLLGII_01527 3.6e-274 ydbT S Bacterial PH domain
OBOLLGII_01528 9.4e-86 S Bacterial PH domain
OBOLLGII_01529 9.6e-86 S AAA domain
OBOLLGII_01530 2.8e-31 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
OBOLLGII_01531 1.2e-188 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OBOLLGII_01532 1.1e-64 argO S Lysine exporter protein LysE YggA
OBOLLGII_01533 3.5e-260 L Transposase DDE domain group 1
OBOLLGII_01535 1.1e-104 lmrA 3.6.3.44 V ABC transporter
OBOLLGII_01536 0.0 L Domain of unknown function (DUF4277)
OBOLLGII_01537 4.7e-190 lmrA 3.6.3.44 V ABC transporter
OBOLLGII_01538 8.2e-100 K DNA-binding transcription factor activity
OBOLLGII_01539 3.3e-253 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OBOLLGII_01540 3.2e-166 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OBOLLGII_01541 7.3e-149 pdaA G deacetylase
OBOLLGII_01542 1.5e-26 yfjT
OBOLLGII_01543 9e-147 yfkD S YfkD-like protein
OBOLLGII_01544 2.9e-172 cax P COG0387 Ca2 H antiporter
OBOLLGII_01545 7e-220 yfkF EGP Major facilitator Superfamily
OBOLLGII_01546 3.1e-145 yihY S Belongs to the UPF0761 family
OBOLLGII_01547 7.3e-33 yfkK S Belongs to the UPF0435 family
OBOLLGII_01548 1.2e-143 map 3.4.11.18 E Methionine aminopeptidase
OBOLLGII_01549 1.3e-90 yfkM 3.5.1.124 S protease
OBOLLGII_01550 6.1e-263 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01551 4.2e-139 motB N Flagellar motor protein
OBOLLGII_01552 6.6e-137 motA N flagellar motor
OBOLLGII_01553 2e-60 yhdN S Domain of unknown function (DUF1992)
OBOLLGII_01555 3.7e-60 yeaO S Protein of unknown function, DUF488
OBOLLGII_01556 1.5e-228 EGP Major facilitator Superfamily
OBOLLGII_01557 1.5e-146 dksA T COG1734 DnaK suppressor protein
OBOLLGII_01558 5.8e-86 ykhA 3.1.2.20 I Acyl-CoA hydrolase
OBOLLGII_01559 2.6e-183 mreB D Rod-share determining protein MreBH
OBOLLGII_01560 1.7e-170 yuaG S protein conserved in bacteria
OBOLLGII_01561 3.6e-89 yuaF OU Membrane protein implicated in regulation of membrane protease activity
OBOLLGII_01562 1.9e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OBOLLGII_01563 5.7e-169 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
OBOLLGII_01564 1.4e-86 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OBOLLGII_01565 1.9e-115 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
OBOLLGII_01566 2.8e-102 4.2.1.1 P Reversible hydration of carbon dioxide
OBOLLGII_01567 1.1e-21 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OBOLLGII_01568 2e-89 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OBOLLGII_01570 1.2e-293 K helix_turn_helix, Lux Regulon
OBOLLGII_01571 1.3e-105 che
OBOLLGII_01572 2.6e-68 S response to pH
OBOLLGII_01573 2e-105
OBOLLGII_01574 2.8e-144 ypuA S Secreted protein
OBOLLGII_01575 5.3e-153 K RpiR family transcriptional regulator
OBOLLGII_01576 2.5e-222 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OBOLLGII_01577 2.1e-225 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OBOLLGII_01578 4.9e-116 cobC 3.1.3.3, 3.1.3.73, 5.4.2.12 G Histidine phosphatase superfamily (branch 1)
OBOLLGII_01579 4.3e-71 K Transcriptional
OBOLLGII_01580 5.8e-39 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OBOLLGII_01581 2.8e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
OBOLLGII_01582 4.9e-98 cas4 3.1.12.1 L RecB family exonuclease
OBOLLGII_01583 9.5e-134 csd2 L CRISPR-associated protein
OBOLLGII_01584 2.6e-211 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
OBOLLGII_01585 1.2e-263 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01586 2.9e-53 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
OBOLLGII_01587 6.3e-56 cas5d S CRISPR-associated protein (Cas_Cas5)
OBOLLGII_01588 7.2e-37 L COG1484 DNA replication protein
OBOLLGII_01589 1.4e-289 L Transposase
OBOLLGII_01591 7.6e-168 L Transposase
OBOLLGII_01593 7.8e-55 L Bacterial dnaA protein
OBOLLGII_01594 4e-157 L PFAM Integrase catalytic
OBOLLGII_01595 1.4e-105 S HTH-like domain
OBOLLGII_01596 1.3e-23 ymbI L Transposase
OBOLLGII_01597 3.3e-64 L COG4584 Transposase and inactivated derivatives
OBOLLGII_01598 1.6e-47 cas5d S CRISPR-associated protein (Cas_Cas5)
OBOLLGII_01599 0.0 cas3 L Metal dependent phosphohydrolases with conserved 'HD' motif.
OBOLLGII_01600 0.0 snf 2.7.11.1 L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OBOLLGII_01601 4e-107 C Nitroreductase family
OBOLLGII_01602 2e-88 1.8.5.2 S DoxX
OBOLLGII_01604 6.2e-210 fni 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OBOLLGII_01605 4.8e-117 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
OBOLLGII_01606 6e-35 yoeD G Helix-turn-helix domain
OBOLLGII_01607 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
OBOLLGII_01608 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OBOLLGII_01609 1.3e-131 fruR K Transcriptional regulator
OBOLLGII_01610 3.8e-204 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OBOLLGII_01611 3.2e-95 D Hemerythrin HHE cation binding
OBOLLGII_01612 8.2e-32
OBOLLGII_01613 2.5e-152 yidA S hydrolases of the HAD superfamily
OBOLLGII_01614 3.5e-57 ygbA S Nitrous oxide-stimulated promoter
OBOLLGII_01615 7.8e-85 G phosphoenolpyruvate-dependent sugar phosphotransferase system
OBOLLGII_01616 1.1e-254 iolT EGP Major facilitator Superfamily
OBOLLGII_01617 2.2e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OBOLLGII_01619 3.8e-70 ywnF S Family of unknown function (DUF5392)
OBOLLGII_01620 2.1e-73 ywaC 2.7.6.5 S protein conserved in bacteria
OBOLLGII_01621 2e-29 ywaC 2.7.6.5 S protein conserved in bacteria
OBOLLGII_01622 2.3e-82 yjjM K FCD
OBOLLGII_01623 7.9e-82 S Carbon-nitrogen hydrolase
OBOLLGII_01624 2.6e-189 puuP E Amino acid permease
OBOLLGII_01625 1e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OBOLLGII_01626 2.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
OBOLLGII_01627 3.6e-100 dhaL 2.7.1.121 S Dak2
OBOLLGII_01628 8.8e-184 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase DhaK, subunit
OBOLLGII_01629 2.6e-173 pfoS S Phosphotransferase system, EIIC
OBOLLGII_01630 6.1e-112 ureH S PFAM Nickel cobalt transporter, high-affinity
OBOLLGII_01631 9.9e-157 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
OBOLLGII_01632 7.3e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OBOLLGII_01633 1.6e-104 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
OBOLLGII_01634 6e-79 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
OBOLLGII_01635 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OBOLLGII_01636 6.7e-56 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OBOLLGII_01637 3.7e-48 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OBOLLGII_01638 6.8e-200 amiF 3.5.1.49 S Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide
OBOLLGII_01639 4.1e-309 F COG1457 Purine-cytosine permease and related proteins
OBOLLGII_01640 6.3e-190 amiE 3.5.1.4 S Carbon-nitrogen hydrolase
OBOLLGII_01641 0.0 KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OBOLLGII_01642 8.8e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
OBOLLGII_01643 8.1e-241 E COG1113 Gamma-aminobutyrate permease and related permeases
OBOLLGII_01644 7.2e-167 ytnM S membrane transporter protein
OBOLLGII_01645 4.6e-225 ywdJ F Xanthine uracil
OBOLLGII_01646 0.0 yjcD 3.6.4.12 L DNA helicase
OBOLLGII_01647 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OBOLLGII_01648 1.9e-70 L Transposase, IS4 family protein
OBOLLGII_01650 4.2e-127 L Transposase, IS4 family protein
OBOLLGII_01651 3.3e-09 L Transposase DDE domain
OBOLLGII_01652 3.6e-82 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
OBOLLGII_01653 7.2e-98 O HI0933-like protein
OBOLLGII_01654 1.6e-79 K Acetyltransferase (GNAT) domain
OBOLLGII_01655 3.3e-46 L COG2963 Transposase and inactivated derivatives
OBOLLGII_01656 2e-126 L COG2801 Transposase and inactivated derivatives
OBOLLGII_01657 2e-254 L Transposase, IS4 family protein
OBOLLGII_01659 1.1e-231 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OBOLLGII_01660 7.1e-253 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OBOLLGII_01661 2.1e-255 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
OBOLLGII_01662 1.4e-267 hsdM 2.1.1.72 V Type I restriction-modification system
OBOLLGII_01664 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
OBOLLGII_01665 3.7e-271 lysP E amino acid
OBOLLGII_01666 3.5e-112 K Transcriptional regulator
OBOLLGII_01667 5e-205 ybhR V COG0842 ABC-type multidrug transport system, permease component
OBOLLGII_01669 5e-128 V COG1131 ABC-type multidrug transport system, ATPase component
OBOLLGII_01670 2.5e-161 fda 4.1.2.13 G Belongs to the class I fructose-bisphosphate aldolase family
OBOLLGII_01672 2.4e-51
OBOLLGII_01674 1.8e-153 galM 5.1.3.3 G Aldose 1-epimerase
OBOLLGII_01675 6.6e-149 L Transposase, IS4 family protein
OBOLLGII_01676 2.6e-75 L Transposase, IS4 family protein
OBOLLGII_01677 2.1e-174 L HKD family nuclease
OBOLLGII_01678 8.4e-53 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OBOLLGII_01679 3.9e-170 mrr V Mrr N-terminal domain
OBOLLGII_01680 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
OBOLLGII_01681 3.1e-66 hsdS-1 3.1.21.3 V Type I restriction modification DNA specificity domain
OBOLLGII_01682 0.0 hsdM 2.1.1.72 V Type I restriction-modification system
OBOLLGII_01683 4e-27
OBOLLGII_01684 9.7e-115 E LysE type translocator
OBOLLGII_01685 2e-85 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OBOLLGII_01686 7.6e-80 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OBOLLGII_01687 2.9e-157 3.2.1.122, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OBOLLGII_01688 1.5e-22 L PFAM Transposase, IS4-like
OBOLLGII_01689 3.5e-36 L PFAM Transposase, IS4-like
OBOLLGII_01690 1.1e-112 L PFAM Transposase, IS4-like
OBOLLGII_01691 3e-118 S YqcI/YcgG family
OBOLLGII_01692 1.6e-97 L Integrase
OBOLLGII_01693 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OBOLLGII_01694 1.3e-23 ymbI L Transposase
OBOLLGII_01695 1.4e-105 S HTH-like domain
OBOLLGII_01696 3.1e-38 K transcriptional
OBOLLGII_01697 1.8e-286 L Transposase
OBOLLGII_01698 1.3e-165 mleR K LysR substrate binding domain
OBOLLGII_01699 5.7e-220 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OBOLLGII_01701 9.4e-91 nrdG 1.97.1.4 O 4Fe-4S single cluster domain
OBOLLGII_01702 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
OBOLLGII_01703 5.2e-206 U protein localization to endoplasmic reticulum
OBOLLGII_01704 1.9e-111 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OBOLLGII_01705 5.8e-197 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OBOLLGII_01706 2.5e-64 L Transposase
OBOLLGII_01707 5.1e-96 S HTH-like domain
OBOLLGII_01708 1.3e-23 ymbI L Transposase
OBOLLGII_01709 2.6e-148 S transposase or invertase
OBOLLGII_01711 9.9e-101 ycnI S Domain of unkown function (DUF1775)
OBOLLGII_01712 3.4e-289 ycnJ P protein, homolog of Cu resistance protein CopC
OBOLLGII_01713 3.5e-26
OBOLLGII_01715 1.4e-289 L Transposase
OBOLLGII_01717 1.4e-289 L Transposase
OBOLLGII_01719 1.1e-237 2.7.13.3 T His Kinase A (phosphoacceptor) domain
OBOLLGII_01720 7.8e-227 2.3.1.179 IQ Beta-ketoacyl synthase, C-terminal domain
OBOLLGII_01721 4.6e-31 cspL K Cold shock
OBOLLGII_01722 3.1e-50 L Transposase
OBOLLGII_01723 1.8e-46 L Transposase IS200 like
OBOLLGII_01724 0.0 nagA 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
OBOLLGII_01725 1.9e-308 ampC V Belongs to the UPF0214 family
OBOLLGII_01726 3.4e-233 ybbC 3.2.1.52 S protein conserved in bacteria
OBOLLGII_01727 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
OBOLLGII_01728 0.0 yfiB V ABC transporter
OBOLLGII_01729 2.5e-80 K helix_turn_helix multiple antibiotic resistance protein
OBOLLGII_01730 1.5e-93 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OBOLLGII_01731 1.3e-11 L Transposase, IS4 family protein
OBOLLGII_01732 1.9e-102 P Integral membrane protein TerC family
OBOLLGII_01733 1.5e-30 S Domain of unknown function (DUF202)
OBOLLGII_01735 3e-248 L PFAM Transposase, IS4-like
OBOLLGII_01736 1.6e-142 XK27_04815 S Membrane transport protein
OBOLLGII_01737 3.5e-304 yhcX K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OBOLLGII_01738 7e-23 S Uncharacterized small protein (DUF2292)
OBOLLGII_01739 6e-94 ssuE 1.5.1.38 S FMN reductase
OBOLLGII_01740 8e-137 ssuB P Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
OBOLLGII_01741 9.9e-135 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OBOLLGII_01742 2.1e-213 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
OBOLLGII_01743 1.7e-163 P ABC transporter substrate-binding protein
OBOLLGII_01744 8.5e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OBOLLGII_01745 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OBOLLGII_01746 4e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OBOLLGII_01747 5e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OBOLLGII_01748 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
OBOLLGII_01749 4.3e-233 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OBOLLGII_01750 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OBOLLGII_01751 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OBOLLGII_01752 1.9e-209 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OBOLLGII_01753 6.2e-225 pbuO_1 S permease
OBOLLGII_01754 1.6e-117 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OBOLLGII_01755 3e-165 S Protein of unknown function (DUF979)
OBOLLGII_01756 8.5e-117 S Protein of unknown function (DUF969)
OBOLLGII_01757 7.4e-138 ycsF S Belongs to the UPF0271 (lamB) family
OBOLLGII_01758 1.4e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
OBOLLGII_01759 5.1e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
OBOLLGII_01760 1.1e-212 EGP Major facilitator Superfamily
OBOLLGII_01761 1.1e-77 ymaD O redox protein, regulator of disulfide bond formation
OBOLLGII_01762 5e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OBOLLGII_01763 6.4e-114 artQ E COG0765 ABC-type amino acid transport system, permease component
OBOLLGII_01764 2e-130 artP ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
OBOLLGII_01765 3.3e-206 hipO3 3.5.1.47 S amidohydrolase
OBOLLGII_01766 0.0 htpG O Molecular chaperone. Has ATPase activity
OBOLLGII_01767 5.7e-184 M FFAT motif binding
OBOLLGII_01768 1.4e-56 I Domain of unknown function (DUF4430)
OBOLLGII_01769 1.9e-90 S Psort location CytoplasmicMembrane, score
OBOLLGII_01770 4.5e-114 crtF 2.1.1.210, 2.1.1.281, 2.1.1.79 M Methyltransferase
OBOLLGII_01771 4.3e-211 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
OBOLLGII_01772 2.5e-30 S Nucleotidyltransferase domain
OBOLLGII_01773 1e-190 adhP 1.1.1.1 C alcohol dehydrogenase
OBOLLGII_01775 1.1e-123 S LXG domain of WXG superfamily
OBOLLGII_01776 3.3e-54 S LXG domain of WXG superfamily
OBOLLGII_01779 3.8e-140 S Protein of unknown function
OBOLLGII_01780 3.4e-267 L Transposase, IS4 family protein
OBOLLGII_01781 2.4e-250 L PFAM transposase IS4 family protein
OBOLLGII_01782 6.4e-11
OBOLLGII_01783 3.4e-130 U COG3267 Type II secretory pathway, component ExeA
OBOLLGII_01784 2.7e-231 L Mu transposase, C-terminal
OBOLLGII_01787 3.5e-154 L COG2801 Transposase and inactivated derivatives
OBOLLGII_01788 3.3e-46 L COG2963 Transposase and inactivated derivatives
OBOLLGII_01789 3.1e-128 V AAA domain (dynein-related subfamily)
OBOLLGII_01790 1e-61 V DNA restriction-modification system
OBOLLGII_01794 3.5e-154 L COG2801 Transposase and inactivated derivatives
OBOLLGII_01795 3.3e-46 L COG2963 Transposase and inactivated derivatives
OBOLLGII_01796 4e-75 U AAA domain
OBOLLGII_01797 0.0 L Domain of unknown function (DUF4277)
OBOLLGII_01799 1.5e-115 L Mu transposase, C-terminal
OBOLLGII_01800 2.9e-149 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01801 1.3e-199 L COG4584 Transposase and inactivated derivatives
OBOLLGII_01802 1.9e-111 L Bacterial dnaA protein
OBOLLGII_01803 4.6e-119 L Mu transposase, C-terminal
OBOLLGII_01804 2.5e-288 L Transposase
OBOLLGII_01807 9.3e-55
OBOLLGII_01808 2.6e-112 L Transposase, IS4 family protein
OBOLLGII_01809 9.9e-109 L Transposase, IS4 family protein
OBOLLGII_01810 1.2e-35 S HTH-like domain
OBOLLGII_01811 3.4e-24 ymbI L Transposase
OBOLLGII_01812 4.6e-112 2.1.1.37 H C-5 cytosine-specific DNA methylase
OBOLLGII_01813 7.4e-31
OBOLLGII_01814 1.8e-193 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01816 9.7e-141
OBOLLGII_01817 2.9e-241 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OBOLLGII_01818 8.1e-267 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OBOLLGII_01819 9.3e-172 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OBOLLGII_01820 7.3e-149 Q N-acetyltransferase
OBOLLGII_01823 3.3e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OBOLLGII_01824 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OBOLLGII_01825 4.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OBOLLGII_01826 1.4e-245 aceA 4.1.3.1 C Isocitrate lyase
OBOLLGII_01827 0.0 aceB 2.3.3.9 C Belongs to the malate synthase family
OBOLLGII_01828 2.7e-216 camS S COG4851 Protein involved in sex pheromone biosynthesis
OBOLLGII_01829 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OBOLLGII_01830 1.2e-283 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OBOLLGII_01831 3.2e-211 L RNA-directed DNA polymerase (reverse transcriptase)
OBOLLGII_01832 7.7e-126 pcrA 3.6.4.12 L AAA domain
OBOLLGII_01833 1.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OBOLLGII_01834 2.2e-54 yerC S protein conserved in bacteria
OBOLLGII_01835 4.2e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
OBOLLGII_01836 0.0 yerA 3.5.4.2 F adenine deaminase
OBOLLGII_01837 3.2e-36 S Protein of unknown function (DUF2892)
OBOLLGII_01838 3.5e-230 purD 6.3.4.13 F Belongs to the GARS family
OBOLLGII_01840 2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OBOLLGII_01841 4.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OBOLLGII_01842 1.3e-190 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OBOLLGII_01843 4.2e-272 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OBOLLGII_01844 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OBOLLGII_01845 3.8e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OBOLLGII_01846 7.1e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OBOLLGII_01847 3.9e-125 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OBOLLGII_01848 4.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OBOLLGII_01849 4.7e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OBOLLGII_01850 3.4e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OBOLLGII_01851 1.1e-30 yebG S NETI protein
OBOLLGII_01852 2.4e-90 yebE S UPF0316 protein
OBOLLGII_01853 1.7e-131 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OBOLLGII_01854 5.3e-43
OBOLLGII_01855 4.3e-42 S COG NOG14552 non supervised orthologous group
OBOLLGII_01856 4.9e-24
OBOLLGII_01857 3.3e-100 L Transposase
OBOLLGII_01858 1.3e-23 ymbI L Transposase
OBOLLGII_01859 2.4e-105 S HTH-like domain
OBOLLGII_01860 2.7e-65 L Transposase
OBOLLGII_01861 2.5e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_01862 9.3e-223 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OBOLLGII_01863 0.0 2.7.1.201, 2.7.1.211 G phosphotransferase system
OBOLLGII_01864 4.8e-154 glcT K antiterminator
OBOLLGII_01865 4.3e-234 pbuG S permease
OBOLLGII_01867 0.0 ywjA V ABC transporter
OBOLLGII_01868 8e-211 ynfM EGP Major facilitator Superfamily
OBOLLGII_01870 3.4e-13 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01872 2.7e-253 ybhI P Sodium:sulfate symporter transmembrane region
OBOLLGII_01873 3.2e-50 L deoxyribonuclease I activity
OBOLLGII_01874 0.0 XK27_11280 S Psort location CytoplasmicMembrane, score
OBOLLGII_01878 6.8e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01879 2.6e-171 tnp4 L Transposase, Mutator family
OBOLLGII_01880 1.9e-57
OBOLLGII_01881 1.1e-135 tnp L PFAM Transposase, Mutator
OBOLLGII_01882 2.5e-56
OBOLLGII_01883 9e-122 yhcG V ABC transporter, ATP-binding protein
OBOLLGII_01884 3.1e-57 yhcF K Transcriptional regulator
OBOLLGII_01885 4.6e-97 padR K transcriptional
OBOLLGII_01886 5.1e-95 padC Q Phenolic acid decarboxylase
OBOLLGII_01887 6.2e-114 ywnB S NAD(P)H-binding
OBOLLGII_01888 9.9e-71 ywnA K Transcriptional regulator
OBOLLGII_01889 3.9e-11
OBOLLGII_01890 2.7e-156 S Radical SAM superfamily
OBOLLGII_01891 8.7e-99 yydH O Peptidase M50
OBOLLGII_01892 1.2e-82 prrC P ABC transporter
OBOLLGII_01893 6.4e-91 S ABC-2 family transporter protein
OBOLLGII_01894 5.5e-13
OBOLLGII_01896 1.3e-23 L Transposase IS66 family
OBOLLGII_01897 1.1e-31 rcfB K Bacterial regulatory proteins, crp family
OBOLLGII_01898 3.2e-16 yeeD O Belongs to the sulfur carrier protein TusA family
OBOLLGII_01899 8.8e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OBOLLGII_01900 9.8e-64 argO S Lysine exporter protein LysE YggA
OBOLLGII_01901 6.6e-11 S transposase or invertase
OBOLLGII_01902 9.5e-14 S transposase or invertase
OBOLLGII_01903 2.7e-158 S transposase or invertase
OBOLLGII_01904 6.9e-36 yeeD O Belongs to the sulfur carrier protein TusA family
OBOLLGII_01905 1.9e-192 yeeE S Sulphur transport
OBOLLGII_01906 1.1e-214 yihS 5.1.3.11, 5.3.1.9 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
OBOLLGII_01907 4.9e-173 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OBOLLGII_01908 1.5e-08
OBOLLGII_01909 2.9e-30 ybxH S Family of unknown function (DUF5370)
OBOLLGII_01910 1.9e-189 P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
OBOLLGII_01911 9.6e-138 fecE 3.6.3.34 HP ABC transporter
OBOLLGII_01912 2.7e-170 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OBOLLGII_01913 5.5e-193 L Transposase DDE domain group 1
OBOLLGII_01914 3.1e-93
OBOLLGII_01916 5.4e-75 P nitrite transmembrane transporter activity
OBOLLGII_01917 2.4e-250 L PFAM transposase IS4 family protein
OBOLLGII_01918 8.8e-63 EGP Major facilitator Superfamily
OBOLLGII_01919 1.4e-27 K Helix-turn-helix domain
OBOLLGII_01920 4.7e-31
OBOLLGII_01921 7.7e-31 S Domain of unknown function (DUF4177)
OBOLLGII_01922 1.2e-299 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OBOLLGII_01924 8e-154 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OBOLLGII_01925 9.4e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OBOLLGII_01926 2.4e-106 pncA Q COG1335 Amidases related to nicotinamidase
OBOLLGII_01927 4.7e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OBOLLGII_01928 0.0 ykoS
OBOLLGII_01929 6.6e-187 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OBOLLGII_01930 4.1e-68 yngA S GtrA-like protein
OBOLLGII_01931 1.6e-283 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OBOLLGII_01932 5.7e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OBOLLGII_01933 2.9e-123 ydiL S CAAX protease self-immunity
OBOLLGII_01934 9.6e-13 S Domain of unknown function (DUF4305)
OBOLLGII_01935 2.9e-251 L PFAM transposase IS4 family protein
OBOLLGII_01936 5.7e-130 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OBOLLGII_01937 4.6e-123 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OBOLLGII_01938 1.1e-09 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OBOLLGII_01939 0.0 ydiF S ABC transporter
OBOLLGII_01940 8.1e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OBOLLGII_01941 2.2e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OBOLLGII_01942 2.8e-128 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
OBOLLGII_01943 5.3e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
OBOLLGII_01945 5.3e-43
OBOLLGII_01946 1.6e-41 S COG NOG14552 non supervised orthologous group
OBOLLGII_01951 1.6e-08
OBOLLGII_01959 3e-92 ydcK S Belongs to the SprT family
OBOLLGII_01960 0.0 yhgF K COG2183 Transcriptional accessory protein
OBOLLGII_01961 5.2e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
OBOLLGII_01962 9.2e-136 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OBOLLGII_01963 6.7e-81 rsbW 2.7.11.1 T Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OBOLLGII_01964 4e-54 rsbV T Belongs to the anti-sigma-factor antagonist family
OBOLLGII_01965 2.5e-186 rsbU 3.1.3.3 KT phosphatase
OBOLLGII_01966 2.9e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OBOLLGII_01967 8.1e-55 rsbS T antagonist
OBOLLGII_01968 4.8e-151 rsbR T Positive regulator of sigma-B
OBOLLGII_01969 7.2e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
OBOLLGII_01970 2e-40 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OBOLLGII_01971 1.7e-215 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OBOLLGII_01972 1.1e-189 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
OBOLLGII_01973 4.2e-56 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OBOLLGII_01974 3.5e-103 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
OBOLLGII_01975 5.8e-208 L Transposase
OBOLLGII_01976 8.2e-64 L Transposase IS200 like
OBOLLGII_01977 8.3e-260 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OBOLLGII_01978 5.5e-107 E Lysine exporter protein LysE YggA
OBOLLGII_01979 4.3e-121 otsB2 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
OBOLLGII_01980 6.1e-174 yvdE K Transcriptional regulator
OBOLLGII_01981 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
OBOLLGII_01982 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
OBOLLGII_01983 4.4e-236 mdxE G COG2182 Maltose-binding periplasmic proteins domains
OBOLLGII_01984 3.3e-239 malC P COG1175 ABC-type sugar transport systems, permease components
OBOLLGII_01985 6.7e-156 malD P transport
OBOLLGII_01986 1.9e-147 malA S Protein of unknown function (DUF1189)
OBOLLGII_01987 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
OBOLLGII_01988 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
OBOLLGII_01989 9.8e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OBOLLGII_01990 5.7e-197 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OBOLLGII_01991 1.2e-21
OBOLLGII_01992 8.5e-265 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_01993 3.2e-118
OBOLLGII_01994 6.1e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OBOLLGII_01995 2.7e-74 cueR K transcriptional
OBOLLGII_01996 1.7e-249 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OBOLLGII_01998 3e-248 L PFAM Transposase, IS4-like
OBOLLGII_01999 1.3e-306 ywqB S Zinc finger, swim domain protein
OBOLLGII_02000 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OBOLLGII_02002 1.9e-71 ywpF S YwpF-like protein
OBOLLGII_02003 3.3e-64 ssbB L Single-stranded DNA-binding protein
OBOLLGII_02005 8.7e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OBOLLGII_02006 1.9e-139 flhP N flagellar basal body
OBOLLGII_02007 5.4e-144 flhO N flagellar basal body
OBOLLGII_02008 1.9e-178 mbl D Rod shape-determining protein
OBOLLGII_02009 6.5e-41 spoIIID K Stage III sporulation protein D
OBOLLGII_02010 1.8e-128 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
OBOLLGII_02011 8.1e-185 spoIID D Stage II sporulation protein D
OBOLLGII_02012 1.2e-08 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OBOLLGII_02013 4.8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OBOLLGII_02014 1.1e-135 ywmB S TATA-box binding
OBOLLGII_02015 6.8e-34 ywzB S membrane
OBOLLGII_02016 1.8e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OBOLLGII_02017 4.5e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OBOLLGII_02018 4.7e-149 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OBOLLGII_02019 5.9e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OBOLLGII_02020 4.9e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OBOLLGII_02021 1.3e-37 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OBOLLGII_02022 1.3e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OBOLLGII_02023 8.2e-131 atpB C it plays a direct role in the translocation of protons across the membrane
OBOLLGII_02024 8e-53 atpI S ATP synthase I chain
OBOLLGII_02025 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OBOLLGII_02026 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OBOLLGII_02027 2.9e-251 L PFAM transposase IS4 family protein
OBOLLGII_02028 3.7e-94 ywlG S Belongs to the UPF0340 family
OBOLLGII_02029 6.9e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
OBOLLGII_02030 4.1e-165 mcpA NT Chemotaxis
OBOLLGII_02031 3.5e-70 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OBOLLGII_02032 7.2e-49 L PFAM transposase, IS4 family protein
OBOLLGII_02033 4.5e-245 L Transposase, IS4 family protein
OBOLLGII_02034 3.8e-145 pdaC 3.5.1.104 G Polysaccharide deacetylase
OBOLLGII_02036 3e-26 L Transposase DDE domain
OBOLLGII_02037 3.8e-183 L Transposase, IS4 family protein
OBOLLGII_02038 3.8e-145 pdaC 3.5.1.104 G Polysaccharide deacetylase
OBOLLGII_02040 3e-26 L Transposase DDE domain
OBOLLGII_02041 3.8e-183 L Transposase, IS4 family protein
OBOLLGII_02042 1.6e-86 mntP P Probably functions as a manganese efflux pump
OBOLLGII_02043 4.2e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OBOLLGII_02044 5.4e-133 spoIIR S Stage II sporulation protein R (spore_II_R)
OBOLLGII_02045 4.1e-161 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OBOLLGII_02046 8.6e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OBOLLGII_02048 1.3e-110 tdk 2.7.1.21 F thymidine kinase
OBOLLGII_02049 2.2e-33 rpmE J Ribosomal protein L31
OBOLLGII_02050 2.7e-230 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OBOLLGII_02052 2.7e-174 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
OBOLLGII_02053 8.1e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OBOLLGII_02054 2.6e-115 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OBOLLGII_02055 3.6e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
OBOLLGII_02056 1.3e-60 spo0F T response regulator
OBOLLGII_02057 2.5e-288 L Transposase
OBOLLGII_02058 2.9e-207
OBOLLGII_02059 3e-140
OBOLLGII_02060 1.3e-23 ymbI L Transposase
OBOLLGII_02061 2.4e-105 S HTH-like domain
OBOLLGII_02062 3.8e-114 yhcG V ABC transporter, ATP-binding protein
OBOLLGII_02063 2e-65 K helix_turn_helix gluconate operon transcriptional repressor
OBOLLGII_02064 9.8e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OBOLLGII_02065 5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OBOLLGII_02067 5.1e-131 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OBOLLGII_02068 1.1e-40 icmF 5.4.99.13 EI Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
OBOLLGII_02069 1.3e-111 kstR2_2 K Transcriptional regulator
OBOLLGII_02070 3.2e-214 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
OBOLLGII_02071 2e-208 mmgC I acyl-CoA dehydrogenase
OBOLLGII_02072 2.9e-218 mmgA 2.3.1.9 I Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
OBOLLGII_02073 0.0 fadF C COG0247 Fe-S oxidoreductase
OBOLLGII_02074 2.7e-211 cls I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OBOLLGII_02075 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OBOLLGII_02076 1.1e-74 ywiB S Domain of unknown function (DUF1934)
OBOLLGII_02077 4.1e-169 speB 3.5.3.11 E Belongs to the arginase family
OBOLLGII_02078 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OBOLLGII_02079 1.7e-93 ywhD S YwhD family
OBOLLGII_02080 6.6e-119 ywhC S Peptidase M50
OBOLLGII_02081 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
OBOLLGII_02082 8.7e-90 ywgA 2.1.1.72, 3.1.21.3
OBOLLGII_02083 6.1e-257 ywfO S COG1078 HD superfamily phosphohydrolases
OBOLLGII_02084 5.7e-100 rsfA S Transcriptional regulator
OBOLLGII_02085 1.8e-153 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OBOLLGII_02087 4.3e-175 pta 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
OBOLLGII_02088 8e-145 ywfI C May function as heme-dependent peroxidase
OBOLLGII_02089 2.5e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_02090 4e-173 L Transposase
OBOLLGII_02091 1.1e-23 ymbI L Transposase
OBOLLGII_02092 1.4e-105 S HTH-like domain
OBOLLGII_02093 2.2e-81 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OBOLLGII_02094 1.1e-57 ywdK S small membrane protein
OBOLLGII_02095 1.9e-34 S Family of unknown function (DUF5327)
OBOLLGII_02096 4.4e-134 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OBOLLGII_02097 2.5e-56 S Heat induced stress protein YflT
OBOLLGII_02099 7.9e-268 L Transposase
OBOLLGII_02100 1.1e-264 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02101 7.6e-165 S membrane
OBOLLGII_02102 1.2e-216 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OBOLLGII_02103 6.8e-158 4.2.3.5 M carboxylic acid catabolic process
OBOLLGII_02104 2.9e-215 amhX S amidohydrolase
OBOLLGII_02105 1e-156 K Helix-turn-helix domain, rpiR family
OBOLLGII_02106 6.2e-151 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OBOLLGII_02107 5.7e-61 yojF S Protein of unknown function (DUF1806)
OBOLLGII_02108 1.6e-128 bshB2 S deacetylase
OBOLLGII_02109 4.4e-163 ycsE S hydrolases of the HAD superfamily
OBOLLGII_02110 0.0 recQ 3.6.4.12 L DNA helicase
OBOLLGII_02111 7.7e-233 phoA 3.1.3.1 P Belongs to the alkaline phosphatase family
OBOLLGII_02112 3.7e-154 ybbH_2 K Transcriptional regulator
OBOLLGII_02113 1.8e-161 S Alpha/beta hydrolase of unknown function (DUF915)
OBOLLGII_02114 7.7e-14
OBOLLGII_02115 8e-230 T His Kinase A (phosphoacceptor) domain
OBOLLGII_02116 1e-78 T Two component transcriptional regulator, winged helix family
OBOLLGII_02117 2e-33 T Two component transcriptional regulator, winged helix family
OBOLLGII_02118 2.4e-77
OBOLLGII_02119 3.3e-115 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OBOLLGII_02121 3.8e-117 ywbG M effector of murein hydrolase
OBOLLGII_02122 5e-55 ywbH S LrgA family
OBOLLGII_02123 9.9e-177 ywbI K Transcriptional regulator
OBOLLGII_02124 0.0 asnO 6.3.5.4 E Asparagine synthase
OBOLLGII_02125 9.7e-154 S Protein of unknown function (DUF1646)
OBOLLGII_02126 1.4e-105 S HTH-like domain
OBOLLGII_02127 1.1e-23 ymbI L Transposase
OBOLLGII_02128 2.3e-16 L Transposase
OBOLLGII_02129 1.9e-288 L Transposase
OBOLLGII_02130 1.3e-145 L Transposase
OBOLLGII_02134 3e-13
OBOLLGII_02135 4.3e-49
OBOLLGII_02138 2.5e-44 XK27_09665 5.4.2.11 G Phosphoglycerate mutase
OBOLLGII_02139 1.4e-72 S Threonine/Serine exporter, ThrE
OBOLLGII_02140 2.6e-127 thrE S Putative threonine/serine exporter
OBOLLGII_02141 2.1e-207 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OBOLLGII_02142 0.0 cstA T Carbon starvation protein
OBOLLGII_02143 2.1e-154 metQ M Belongs to the nlpA lipoprotein family
OBOLLGII_02144 2.9e-98 metI P COG2011 ABC-type metal ion transport system, permease component
OBOLLGII_02145 3.3e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OBOLLGII_02146 6.2e-140 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OBOLLGII_02147 4e-96
OBOLLGII_02148 1.8e-220 pilM NU Pilus assembly protein
OBOLLGII_02149 3.1e-240 yisQ V Mate efflux family protein
OBOLLGII_02150 6.5e-153 M Glycosyl transferase family 8
OBOLLGII_02151 3.7e-232 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OBOLLGII_02154 2.9e-271 EGP Major facilitator Superfamily
OBOLLGII_02155 1.2e-09 S Leucine-rich repeat (LRR) protein
OBOLLGII_02156 2.1e-225 uraA F Xanthine uracil
OBOLLGII_02157 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OBOLLGII_02158 7.3e-225 L PFAM Transposase, IS116 IS110 IS902
OBOLLGII_02159 4.6e-156 L Transposase DDE domain group 1
OBOLLGII_02160 2e-36 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02161 1.2e-29 3.2.1.78 GH26 O cellulase activity
OBOLLGII_02162 1.4e-206 ugpC 3.6.3.20 P Belongs to the ABC transporter superfamily
OBOLLGII_02163 2.2e-168 ugpA G ABC transporter (permease)
OBOLLGII_02164 1.9e-147 ugpE P Glycerol-3-phosphate ABC transporter permease
OBOLLGII_02166 4e-248 ugpB G Glycerol-3-phosphate ABC transporter substrate-binding protein
OBOLLGII_02167 4.5e-146 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OBOLLGII_02168 1.3e-60 S Domain of unknown function (DUF2935)
OBOLLGII_02169 2.9e-32 tnp4 L Transposase, Mutator family
OBOLLGII_02170 2.6e-201 L Transposase, IS4 family protein
OBOLLGII_02171 6.8e-48 L Transposase, IS4 family protein
OBOLLGII_02172 9.1e-301 msbA2 3.6.3.44 V ABC transporter
OBOLLGII_02173 3.2e-113 yhhQ_2 S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OBOLLGII_02174 2.9e-98 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OBOLLGII_02175 7.7e-104 S MMPL domain protein
OBOLLGII_02176 1.5e-264 S MMPL domain protein
OBOLLGII_02177 1.4e-299 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
OBOLLGII_02178 2.4e-43 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
OBOLLGII_02179 1.2e-143 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OBOLLGII_02180 2.4e-250 L PFAM transposase IS4 family protein
OBOLLGII_02181 8.9e-239 LYS1 1.5.1.7 E Saccharopine dehydrogenase
OBOLLGII_02182 4.9e-223 nspC 4.1.1.96 E Pyridoxal-dependent decarboxylase, C-terminal sheet domain
OBOLLGII_02183 8.1e-207 S Domain of unknown function (DUF1611_N) Rossmann-like domain
OBOLLGII_02184 4.3e-214 5.1.1.12 E Alanine racemase, N-terminal domain
OBOLLGII_02185 6.2e-138 cjaA ET Belongs to the bacterial solute-binding protein 3 family
OBOLLGII_02186 1.8e-128 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
OBOLLGII_02187 1.4e-103 E amino acid ABC transporter
OBOLLGII_02188 1.2e-75 papP E amino acid ABC transporter
OBOLLGII_02189 3e-248 L PFAM Transposase, IS4-like
OBOLLGII_02190 2.3e-60 L Transposase, IS4 family protein
OBOLLGII_02191 8e-136 L Transposase, IS4 family protein
OBOLLGII_02192 6.6e-31 papP E amino acid ABC transporter
OBOLLGII_02193 4.2e-294 mqo 1.1.5.4 S malate quinone oxidoreductase
OBOLLGII_02194 1.3e-119 L Transposase IS4 family protein
OBOLLGII_02195 2.2e-75 5.4.2.11 G Phosphoglycerate mutase family
OBOLLGII_02196 1.8e-162 L Transposase
OBOLLGII_02197 1.9e-39 L IstB-like ATP binding protein
OBOLLGII_02198 7.3e-138 L SMART ATPase, AAA type, core
OBOLLGII_02199 7.3e-266 L PFAM Integrase, catalytic core
OBOLLGII_02200 1.5e-208 L PFAM Transposase, IS4-like
OBOLLGII_02201 3.5e-239 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02202 6.4e-11
OBOLLGII_02203 3.4e-130 U COG3267 Type II secretory pathway, component ExeA
OBOLLGII_02204 2.7e-231 L Mu transposase, C-terminal
OBOLLGII_02207 9.2e-46 L IstB-like ATP binding protein
OBOLLGII_02209 1.4e-264 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02211 5.6e-75 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OBOLLGII_02212 1.4e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OBOLLGII_02213 9e-147 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OBOLLGII_02214 4.3e-141 yycI S protein conserved in bacteria
OBOLLGII_02215 2.9e-243 yycH S protein conserved in bacteria
OBOLLGII_02216 0.0 vicK 2.7.13.3 T Histidine kinase
OBOLLGII_02217 1.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OBOLLGII_02221 5.6e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OBOLLGII_02222 2.2e-249 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OBOLLGII_02223 5.3e-72 rplI J binds to the 23S rRNA
OBOLLGII_02224 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OBOLLGII_02225 4.6e-158 yybS S membrane
OBOLLGII_02226 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OBOLLGII_02227 3.2e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OBOLLGII_02228 5e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
OBOLLGII_02229 1.6e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OBOLLGII_02230 2.2e-221 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OBOLLGII_02231 1.6e-117 ribE 2.5.1.9 H Riboflavin synthase
OBOLLGII_02232 4e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OBOLLGII_02233 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OBOLLGII_02234 1.1e-32 yyzM S protein conserved in bacteria
OBOLLGII_02235 5.9e-158 ykuT M Mechanosensitive ion channel
OBOLLGII_02236 1.5e-112 yyaC S Sporulation protein YyaC
OBOLLGII_02237 3.2e-119 ydfK S Protein of unknown function (DUF554)
OBOLLGII_02238 5e-151 spo0J K Belongs to the ParB family
OBOLLGII_02239 6.9e-136 soj D COG1192 ATPases involved in chromosome partitioning
OBOLLGII_02241 9.1e-153 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OBOLLGII_02242 7.4e-132 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OBOLLGII_02243 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OBOLLGII_02244 5.3e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OBOLLGII_02245 1.3e-108 jag S single-stranded nucleic acid binding R3H
OBOLLGII_02246 3.2e-128 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OBOLLGII_02247 4.2e-56 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OBOLLGII_02248 9e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OBOLLGII_02249 1e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OBOLLGII_02250 6.8e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02252 2.7e-32 yaaA S S4 domain
OBOLLGII_02253 3.5e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OBOLLGII_02254 9.6e-11 yaaB S Domain of unknown function (DUF370)
OBOLLGII_02255 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OBOLLGII_02256 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OBOLLGII_02257 7.5e-197 M1-161 T HD domain
OBOLLGII_02258 4.3e-42 S COG NOG14552 non supervised orthologous group
OBOLLGII_02261 5.3e-43
OBOLLGII_02262 2.4e-30 csfB S Inhibitor of sigma-G Gin
OBOLLGII_02263 1.4e-281 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
OBOLLGII_02264 2.3e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OBOLLGII_02265 9.8e-55 yaaQ S protein conserved in bacteria
OBOLLGII_02266 1.5e-71 yaaR S protein conserved in bacteria
OBOLLGII_02267 6.8e-184 holB 2.7.7.7 L DNA polymerase III
OBOLLGII_02268 1.7e-148 yaaT S stage 0 sporulation protein
OBOLLGII_02269 1.9e-65 yabA L Involved in initiation control of chromosome replication
OBOLLGII_02270 1.6e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
OBOLLGII_02271 7.1e-49 yazA L endonuclease containing a URI domain
OBOLLGII_02272 2.6e-163 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OBOLLGII_02273 4.8e-55 abrB K COG2002 Regulators of stationary sporulation gene expression
OBOLLGII_02274 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OBOLLGII_02275 8e-148 tatD L hydrolase, TatD
OBOLLGII_02276 5e-105 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OBOLLGII_02277 2.7e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OBOLLGII_02278 6.4e-162 yabG S peptidase
OBOLLGII_02279 2.4e-37 veg S protein conserved in bacteria
OBOLLGII_02280 1.9e-26 sspF S DNA topological change
OBOLLGII_02281 7.3e-158 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OBOLLGII_02282 1.3e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OBOLLGII_02283 1.2e-61 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
OBOLLGII_02284 1.4e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OBOLLGII_02286 1.2e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OBOLLGII_02287 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OBOLLGII_02288 1.7e-108 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OBOLLGII_02289 2.7e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OBOLLGII_02290 1.8e-36 yabK S Peptide ABC transporter permease
OBOLLGII_02291 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OBOLLGII_02292 2.1e-91 spoVT K stage V sporulation protein
OBOLLGII_02293 2.1e-275 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OBOLLGII_02294 3.1e-190 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OBOLLGII_02295 2.4e-41 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OBOLLGII_02296 3e-50 yabP S Sporulation protein YabP
OBOLLGII_02297 8e-106 yabQ S spore cortex biosynthesis protein
OBOLLGII_02298 1.9e-60 divIC D Septum formation initiator
OBOLLGII_02299 3.7e-54 yabR J RNA binding protein (contains ribosomal protein S1 domain)
OBOLLGII_02301 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
OBOLLGII_02302 8.7e-120 yabS S protein containing a von Willebrand factor type A (vWA) domain
OBOLLGII_02303 2.8e-166 KLT serine threonine protein kinase
OBOLLGII_02304 4e-278 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OBOLLGII_02305 2.9e-96 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OBOLLGII_02306 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OBOLLGII_02307 1.7e-159 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OBOLLGII_02308 8.4e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OBOLLGII_02309 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OBOLLGII_02310 1.7e-156 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OBOLLGII_02311 6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OBOLLGII_02312 1.1e-97 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OBOLLGII_02315 2.7e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OBOLLGII_02316 4.3e-42 S COG NOG14552 non supervised orthologous group
OBOLLGII_02317 5.3e-43
OBOLLGII_02320 1.6e-08
OBOLLGII_02321 4e-08
OBOLLGII_02325 4.3e-42 S COG NOG14552 non supervised orthologous group
OBOLLGII_02326 5.3e-43
OBOLLGII_02327 8.1e-179 yaaC S YaaC-like Protein
OBOLLGII_02328 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OBOLLGII_02329 2.7e-241 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OBOLLGII_02330 3.7e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OBOLLGII_02331 1.3e-102 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OBOLLGII_02332 2.9e-211 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OBOLLGII_02333 2.9e-09
OBOLLGII_02334 3.3e-126 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
OBOLLGII_02335 1.4e-118 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
OBOLLGII_02336 1.1e-142 yaaH M Glycoside Hydrolase Family
OBOLLGII_02338 2.1e-88 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OBOLLGII_02339 5.3e-306 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OBOLLGII_02340 1.3e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OBOLLGII_02341 1.5e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OBOLLGII_02342 3.4e-08 yaaL S Protein of unknown function (DUF2508)
OBOLLGII_02343 7.5e-37 bofA S Sigma-K factor-processing regulatory protein BofA
OBOLLGII_02344 4.3e-42 S COG NOG14552 non supervised orthologous group
OBOLLGII_02347 5.3e-43
OBOLLGII_02348 5.4e-75 ctsR K Belongs to the CtsR family
OBOLLGII_02349 1.3e-99 mcsA 2.7.14.1 S protein with conserved CXXC pairs
OBOLLGII_02350 7.3e-192 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OBOLLGII_02351 0.0 clpC O Belongs to the ClpA ClpB family
OBOLLGII_02352 2.9e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OBOLLGII_02353 6.9e-198 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
OBOLLGII_02354 2.6e-118 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OBOLLGII_02355 2.1e-82 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OBOLLGII_02356 1.9e-283 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OBOLLGII_02357 7.7e-115 cysE 2.3.1.30 E Serine acetyltransferase
OBOLLGII_02358 1.6e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OBOLLGII_02359 3e-69 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OBOLLGII_02360 8.2e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OBOLLGII_02361 4.6e-69 yacP S RNA-binding protein containing a PIN domain
OBOLLGII_02362 1.8e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02363 7.2e-110 sigH K Belongs to the sigma-70 factor family
OBOLLGII_02364 6.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OBOLLGII_02365 9.2e-95 nusG K Participates in transcription elongation, termination and antitermination
OBOLLGII_02366 1.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OBOLLGII_02367 4.3e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OBOLLGII_02368 1e-08 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OBOLLGII_02369 5.4e-81 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OBOLLGII_02370 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OBOLLGII_02371 6.5e-113 rsmC 2.1.1.172 J Methyltransferase
OBOLLGII_02372 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OBOLLGII_02373 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OBOLLGII_02374 1.2e-36 rplGB J Belongs to the eukaryotic ribosomal protein eL8 family
OBOLLGII_02375 8.6e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OBOLLGII_02376 9.3e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OBOLLGII_02377 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OBOLLGII_02378 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OBOLLGII_02379 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OBOLLGII_02380 2.6e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OBOLLGII_02381 1.1e-107 rplD J Forms part of the polypeptide exit tunnel
OBOLLGII_02382 6.3e-42 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OBOLLGII_02383 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OBOLLGII_02384 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OBOLLGII_02385 6.6e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OBOLLGII_02386 1.4e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OBOLLGII_02387 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OBOLLGII_02388 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
OBOLLGII_02389 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OBOLLGII_02390 1.5e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OBOLLGII_02391 9.6e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OBOLLGII_02392 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OBOLLGII_02393 5.8e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OBOLLGII_02394 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OBOLLGII_02395 1.1e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OBOLLGII_02396 2.3e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OBOLLGII_02397 6.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OBOLLGII_02398 4.1e-23 rpmD J Ribosomal protein L30
OBOLLGII_02399 1.2e-71 rplO J binds to the 23S rRNA
OBOLLGII_02400 6.9e-229 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OBOLLGII_02401 9.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OBOLLGII_02402 2.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OBOLLGII_02403 1.8e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OBOLLGII_02404 2e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OBOLLGII_02405 5.8e-169 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OBOLLGII_02406 1.6e-59 rplQ J Ribosomal protein L17
OBOLLGII_02407 1.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OBOLLGII_02408 2.2e-162 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OBOLLGII_02409 2.7e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OBOLLGII_02410 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OBOLLGII_02411 3.8e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OBOLLGII_02412 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OBOLLGII_02413 5.7e-09 S Protein conserved in bacteria
OBOLLGII_02415 1.9e-225 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OBOLLGII_02416 1.1e-110 cysC 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
OBOLLGII_02417 6.8e-273 lysP E amino acid
OBOLLGII_02418 9.7e-82 ybaK S Protein of unknown function (DUF2521)
OBOLLGII_02419 2.4e-130 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OBOLLGII_02420 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OBOLLGII_02422 1.4e-61 gerD S Spore gernimation protein
OBOLLGII_02423 2.3e-100 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OBOLLGII_02424 5.3e-211 S Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
OBOLLGII_02425 1.3e-173 K Transcriptional regulator
OBOLLGII_02426 1.2e-58 yrkC G Cupin domain
OBOLLGII_02427 1.6e-210 L COG4584 Transposase and inactivated derivatives
OBOLLGII_02428 3.3e-207 L COG3547 Transposase and inactivated derivatives
OBOLLGII_02429 1.9e-111 L Bacterial dnaA protein
OBOLLGII_02430 4.9e-76
OBOLLGII_02431 5.5e-138 pdaB 3.5.1.104 G xylanase chitin deacetylase
OBOLLGII_02432 1.2e-30
OBOLLGII_02433 1.6e-260 cydA 1.10.3.14 C oxidase, subunit
OBOLLGII_02434 2.2e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
OBOLLGII_02435 0.0 cydD V ATP-binding
OBOLLGII_02436 0.0 cydD V ATP-binding protein
OBOLLGII_02437 4.3e-42 S COG NOG14552 non supervised orthologous group
OBOLLGII_02438 5.3e-43
OBOLLGII_02443 1.7e-07
OBOLLGII_02444 1.5e-07
OBOLLGII_02448 6.3e-131 L Phage integrase, N-terminal SAM-like domain
OBOLLGII_02449 6.9e-74 yokF 3.1.31.1 L RNA catabolic process
OBOLLGII_02451 4.5e-16 S IrrE N-terminal-like domain
OBOLLGII_02452 1.8e-18 K Helix-turn-helix XRE-family like proteins
OBOLLGII_02453 1.3e-16 2.3.1.19 K sequence-specific DNA binding
OBOLLGII_02454 7.8e-58 K BRO family, N-terminal domain
OBOLLGII_02455 7.3e-15 S Helix-turn-helix domain
OBOLLGII_02456 1.4e-15
OBOLLGII_02461 3.6e-10 S Hypothetical protein Yqai
OBOLLGII_02462 7.7e-137 yqaJ L YqaJ-like viral recombinase domain
OBOLLGII_02463 8e-123 recT L RecT family
OBOLLGII_02464 9.6e-27 L Replication initiation and membrane attachment
OBOLLGII_02465 1.3e-13 xkdC L Bacterial dnaA protein
OBOLLGII_02466 5e-90 xkdC L Bacterial dnaA protein
OBOLLGII_02470 4.6e-45 S dUTPase
OBOLLGII_02471 1.5e-53 S Protein of unknown function (DUF1064)
OBOLLGII_02472 1.7e-48 V N-6 DNA Methylase
OBOLLGII_02473 2.5e-13 S Protein of unknown function (DUF3954)
OBOLLGII_02478 1.3e-07
OBOLLGII_02479 3.3e-207 L COG3547 Transposase and inactivated derivatives
OBOLLGII_02480 8.9e-48 L crispr-associated protein
OBOLLGII_02481 2.9e-08
OBOLLGII_02482 6.5e-11 S Pfam:DUF2276
OBOLLGII_02483 4.4e-13 cysH 1.8.4.10, 1.8.4.8 EH Belongs to the PAPS reductase family. CysH subfamily
OBOLLGII_02484 1.3e-23 ymbI L Transposase
OBOLLGII_02485 3e-96 S HTH-like domain
OBOLLGII_02486 1.2e-37 L Transposase
OBOLLGII_02488 7.5e-82 yqaS L DNA packaging
OBOLLGII_02489 4.6e-201 S Terminase RNAseH like domain
OBOLLGII_02490 8.6e-154 S portal protein
OBOLLGII_02491 4.8e-130 M Phage minor capsid protein 2
OBOLLGII_02494 3.7e-12
OBOLLGII_02495 5.9e-22
OBOLLGII_02496 1e-125
OBOLLGII_02497 6.7e-13
OBOLLGII_02498 1.5e-14
OBOLLGII_02499 4.7e-07 S Minor capsid protein
OBOLLGII_02500 6.2e-31 S Minor capsid protein
OBOLLGII_02501 6.1e-39 S Minor capsid protein from bacteriophage
OBOLLGII_02502 5.5e-16
OBOLLGII_02503 3.8e-17 L PFAM Transposase, IS4-like
OBOLLGII_02504 1.4e-92 L PFAM Transposase, IS4-like
OBOLLGII_02506 8.5e-52 S Bacteriophage Gp15 protein
OBOLLGII_02507 1.1e-128 L Transglycosylase SLT domain
OBOLLGII_02508 7.3e-271 S Phage tail protein
OBOLLGII_02509 1.2e-30 S HNH endonuclease
OBOLLGII_02510 1.4e-168
OBOLLGII_02511 5.2e-33 D nuclear chromosome segregation
OBOLLGII_02512 7.4e-26 S Protein of unknown function (DUF1617)
OBOLLGII_02514 2.9e-251 L PFAM transposase IS4 family protein
OBOLLGII_02515 3.2e-42
OBOLLGII_02516 8.5e-24 S SPP1 phage holin
OBOLLGII_02517 1.1e-69 ampD 3.5.1.104, 3.5.1.28 M family 25
OBOLLGII_02518 3e-248 L PFAM Transposase, IS4-like
OBOLLGII_02520 7.4e-86
OBOLLGII_02521 2.9e-63 S Streptococcus thermophilus bacteriophage Gp111 protein
OBOLLGII_02522 3.3e-14 S Protein of unknown function (DUF3006)
OBOLLGII_02523 7.9e-136 S Metallo-beta-lactamase superfamily
OBOLLGII_02524 6.3e-131 L Phage integrase, N-terminal SAM-like domain
OBOLLGII_02525 6.9e-74 yokF 3.1.31.1 L RNA catabolic process
OBOLLGII_02527 4.5e-16 S IrrE N-terminal-like domain
OBOLLGII_02528 1.8e-18 K Helix-turn-helix XRE-family like proteins
OBOLLGII_02529 1.3e-16 2.3.1.19 K sequence-specific DNA binding
OBOLLGII_02530 7.8e-58 K BRO family, N-terminal domain
OBOLLGII_02531 7.3e-15 S Helix-turn-helix domain
OBOLLGII_02532 1.4e-15
OBOLLGII_02537 3.6e-10 S Hypothetical protein Yqai
OBOLLGII_02538 7.7e-137 yqaJ L YqaJ-like viral recombinase domain
OBOLLGII_02539 8e-123 recT L RecT family
OBOLLGII_02540 9.6e-27 L Replication initiation and membrane attachment
OBOLLGII_02541 1.3e-13 xkdC L Bacterial dnaA protein
OBOLLGII_02542 5e-90 xkdC L Bacterial dnaA protein
OBOLLGII_02546 4.6e-45 S dUTPase
OBOLLGII_02547 1.5e-53 S Protein of unknown function (DUF1064)
OBOLLGII_02548 1.7e-48 V N-6 DNA Methylase
OBOLLGII_02549 2.5e-13 S Protein of unknown function (DUF3954)
OBOLLGII_02554 1.3e-07
OBOLLGII_02555 9.8e-31 L COG3547 Transposase and inactivated derivatives
OBOLLGII_02556 6.5e-155 L COG3547 Transposase and inactivated derivatives
OBOLLGII_02559 6.5e-11 S Pfam:DUF2276
OBOLLGII_02560 4.4e-13 cysH 1.8.4.10, 1.8.4.8 EH Belongs to the PAPS reductase family. CysH subfamily
OBOLLGII_02561 1.3e-23 ymbI L Transposase
OBOLLGII_02562 1.4e-105 S HTH-like domain
OBOLLGII_02563 1.2e-37 L Transposase
OBOLLGII_02565 7.5e-82 yqaS L DNA packaging
OBOLLGII_02566 4.6e-201 S Terminase RNAseH like domain
OBOLLGII_02567 8.6e-154 S portal protein
OBOLLGII_02568 4.8e-130 M Phage minor capsid protein 2
OBOLLGII_02571 3.7e-12
OBOLLGII_02572 5.9e-22
OBOLLGII_02573 1e-125
OBOLLGII_02574 6.7e-13
OBOLLGII_02575 1.5e-14
OBOLLGII_02576 4.7e-07 S Minor capsid protein
OBOLLGII_02577 6.2e-31 S Minor capsid protein
OBOLLGII_02578 6.1e-39 S Minor capsid protein from bacteriophage
OBOLLGII_02579 5.5e-16
OBOLLGII_02580 3e-248 L PFAM Transposase, IS4-like
OBOLLGII_02582 8.5e-52 S Bacteriophage Gp15 protein
OBOLLGII_02583 1.1e-128 L Transglycosylase SLT domain
OBOLLGII_02584 7.3e-271 S Phage tail protein
OBOLLGII_02585 1.2e-30 S HNH endonuclease
OBOLLGII_02586 1.4e-168
OBOLLGII_02587 5.2e-33 D nuclear chromosome segregation
OBOLLGII_02588 7.4e-26 S Protein of unknown function (DUF1617)
OBOLLGII_02590 2.9e-251 L PFAM transposase IS4 family protein
OBOLLGII_02591 3.2e-42
OBOLLGII_02592 8.5e-24 S SPP1 phage holin
OBOLLGII_02593 1.1e-69 ampD 3.5.1.104, 3.5.1.28 M family 25
OBOLLGII_02594 6.9e-231 L PFAM Transposase, IS4-like
OBOLLGII_02596 7.4e-86
OBOLLGII_02597 2.9e-63 S Streptococcus thermophilus bacteriophage Gp111 protein
OBOLLGII_02598 3.3e-14 S Protein of unknown function (DUF3006)
OBOLLGII_02599 7.9e-136 S Metallo-beta-lactamase superfamily
OBOLLGII_02600 1.1e-169 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OBOLLGII_02602 2.8e-11 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OBOLLGII_02603 1.4e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02604 1.2e-78 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OBOLLGII_02605 3.2e-115 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OBOLLGII_02606 2.4e-105 S HTH-like domain
OBOLLGII_02607 1.3e-23 ymbI L Transposase
OBOLLGII_02608 2.4e-250 L PFAM transposase IS4 family protein
OBOLLGII_02609 4.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OBOLLGII_02610 1e-216 ybbR S protein conserved in bacteria
OBOLLGII_02611 5.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OBOLLGII_02612 6.8e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02613 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OBOLLGII_02614 1.7e-67 K helix_turn_helix, Arsenical Resistance Operon Repressor
OBOLLGII_02615 3.6e-48 ykvR S Protein of unknown function (DUF3219)
OBOLLGII_02616 3.7e-174 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OBOLLGII_02617 6.7e-58 V CAAX protease self-immunity
OBOLLGII_02619 3.1e-55 L Transposase, IS4 family protein
OBOLLGII_02620 9.7e-172 L Transposase, IS4 family protein
OBOLLGII_02621 2.9e-251 L PFAM transposase IS4 family protein
OBOLLGII_02622 5e-213 G Major facilitator Superfamily
OBOLLGII_02623 3.7e-65 S Pfam:DUF1399
OBOLLGII_02624 3.3e-09 S Pfam:DUF1399
OBOLLGII_02625 1.5e-236 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 I Hydroxymethylglutaryl-coenzyme A reductase
OBOLLGII_02626 1.6e-221 mvaS 2.3.3.10 I synthase
OBOLLGII_02627 1.5e-209 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
OBOLLGII_02628 5e-54 S DsrE/DsrF-like family
OBOLLGII_02629 1.5e-74
OBOLLGII_02630 1.4e-181 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OBOLLGII_02631 7e-178 proV E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OBOLLGII_02632 8.9e-268 proWX EM COG1174 ABC-type proline glycine betaine transport systems, permease component
OBOLLGII_02633 1.1e-81 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OBOLLGII_02634 6.5e-265 treP 2.7.1.201, 2.7.1.211 G phosphotransferase system
OBOLLGII_02635 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OBOLLGII_02636 7.4e-132 treR K transcriptional
OBOLLGII_02637 1.7e-230 EG COG2610 H gluconate symporter and related permeases
OBOLLGII_02638 2.9e-306 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
OBOLLGII_02639 5e-125 gntR K transcriptional
OBOLLGII_02640 4.9e-173 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
OBOLLGII_02641 6.5e-81 fld C Flavodoxin
OBOLLGII_02642 1.9e-200 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OBOLLGII_02643 2.1e-137 4.1.99.16, 4.2.3.22, 4.2.3.75 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
OBOLLGII_02644 0.0 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
OBOLLGII_02645 1.3e-29 P Heavy-metal-associated domain
OBOLLGII_02646 5.6e-40
OBOLLGII_02648 0.0 nrdA 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OBOLLGII_02649 5.6e-88 fld C Flavodoxin
OBOLLGII_02650 4.9e-193 nrdB 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OBOLLGII_02651 3.6e-103 plsY 2.3.1.15 I Belongs to the PlsY family
OBOLLGII_02652 6.9e-206 crtQ M Glycosyl transferase family 21
OBOLLGII_02653 4.8e-20 S transposase or invertase
OBOLLGII_02654 1e-92 Q Thioesterase superfamily
OBOLLGII_02655 5e-48 sugE P Multidrug resistance protein
OBOLLGII_02656 1.1e-53 ykkC P Multidrug resistance protein
OBOLLGII_02657 4.1e-136 yfcA S membrane transporter protein
OBOLLGII_02658 1.3e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OBOLLGII_02659 3.7e-180 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OBOLLGII_02660 2.9e-171 fhuD P Periplasmic binding protein
OBOLLGII_02661 1.4e-150 fhuC 3.6.3.34 HP ABC transporter
OBOLLGII_02662 2.8e-196 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OBOLLGII_02663 1.9e-105
OBOLLGII_02664 3.2e-98
OBOLLGII_02665 3.2e-127 yeeN K transcriptional regulatory protein
OBOLLGII_02666 1.4e-187 T Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)
OBOLLGII_02667 1.9e-236 MA20_26760 1.3.8.7 I COG1960 Acyl-CoA dehydrogenases
OBOLLGII_02668 2.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OBOLLGII_02669 2.1e-28 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OBOLLGII_02670 6.1e-134 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OBOLLGII_02671 3.3e-109 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OBOLLGII_02672 1.2e-97 K Transcriptional regulator
OBOLLGII_02673 4.6e-70 S Thioesterase-like superfamily
OBOLLGII_02674 3.9e-206 S Phosphotransferase enzyme family
OBOLLGII_02675 1.5e-231 L PFAM Transposase, IS4-like
OBOLLGII_02676 2e-24 L PFAM Transposase, IS4-like
OBOLLGII_02677 6.4e-11
OBOLLGII_02678 3.4e-130 U COG3267 Type II secretory pathway, component ExeA
OBOLLGII_02679 4.2e-73 L Mu transposase, C-terminal
OBOLLGII_02680 5.7e-136 L Mu transposase, C-terminal
OBOLLGII_02682 2e-85 L PFAM Transposase, IS4-like
OBOLLGII_02683 1.2e-106 L PFAM Transposase, IS4-like
OBOLLGII_02684 5.9e-88 L Transposase DDE domain
OBOLLGII_02685 3.7e-247 L Transposase, IS4 family protein
OBOLLGII_02686 1.3e-96 ymcC S Membrane
OBOLLGII_02687 6.5e-102 pksA K Transcriptional regulator
OBOLLGII_02688 1e-289 L Transposase
OBOLLGII_02689 2.2e-50 L Transposase
OBOLLGII_02690 4e-270 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OBOLLGII_02694 2.4e-283 yobO M Pectate lyase superfamily protein
OBOLLGII_02695 1.1e-07
OBOLLGII_02696 4.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OBOLLGII_02697 2.3e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OBOLLGII_02698 6.3e-126 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
OBOLLGII_02699 1.7e-103 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
OBOLLGII_02700 3.1e-95 ywhH S Aminoacyl-tRNA editing domain
OBOLLGII_02701 6.5e-204 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OBOLLGII_02702 1.3e-36 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02703 3.4e-13 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02704 2.8e-309 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OBOLLGII_02705 1.5e-77 L transposase, IS605 OrfB family
OBOLLGII_02707 2.6e-169 EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OBOLLGII_02709 1.7e-178 S Nuclease-related domain
OBOLLGII_02710 9e-89
OBOLLGII_02711 7.3e-172 czcD P COG1230 Co Zn Cd efflux system component
OBOLLGII_02712 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OBOLLGII_02713 7.9e-293 M Glycosyltransferase like family 2
OBOLLGII_02714 1.6e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases C terminal
OBOLLGII_02715 6.9e-181 mvaD 4.1.1.33 I GHMP kinases N terminal domain
OBOLLGII_02716 1.6e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases C terminal
OBOLLGII_02717 2e-112 yhfK GM NmrA-like family
OBOLLGII_02718 2.5e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_02719 7.3e-211 L Transposase
OBOLLGII_02720 4.8e-229 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OBOLLGII_02721 6.7e-108 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OBOLLGII_02722 2.9e-251 L PFAM transposase IS4 family protein
OBOLLGII_02723 5.2e-38 gcvR T Belongs to the UPF0237 family
OBOLLGII_02724 4.8e-249 XK27_08635 S UPF0210 protein
OBOLLGII_02726 3e-248 L PFAM Transposase, IS4-like
OBOLLGII_02728 2.6e-35 ptxS K transcriptional
OBOLLGII_02729 2.6e-92 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M SIS domain
OBOLLGII_02730 1.2e-83 cotF M Spore coat protein
OBOLLGII_02731 5.4e-175 iolS C Aldo keto reductase
OBOLLGII_02732 1.2e-97 ydjA C Nitroreductase family
OBOLLGII_02733 1.2e-244 E COG1113 Gamma-aminobutyrate permease and related permeases
OBOLLGII_02734 3.3e-46 L COG2963 Transposase and inactivated derivatives
OBOLLGII_02735 3.5e-154 L COG2801 Transposase and inactivated derivatives
OBOLLGII_02737 4.8e-274 dtpT E amino acid peptide transporter
OBOLLGII_02738 8.4e-279 lysP E amino acid
OBOLLGII_02740 4.3e-98 puuR K Cupin domain
OBOLLGII_02741 1.2e-210 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
OBOLLGII_02742 1.8e-139 potB E COG1176 ABC-type spermidine putrescine transport system, permease component I
OBOLLGII_02743 5.4e-139 potC E COG1177 ABC-type spermidine putrescine transport system, permease component II
OBOLLGII_02744 9.8e-205 potD E COG0687 Spermidine putrescine-binding periplasmic protein
OBOLLGII_02745 3.4e-250 H HemY protein
OBOLLGII_02746 6.3e-252 E amino acid
OBOLLGII_02747 1e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OBOLLGII_02748 8.6e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OBOLLGII_02749 2.5e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OBOLLGII_02750 1.5e-250 E Amino acid permease
OBOLLGII_02751 8.6e-223 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
OBOLLGII_02752 2.6e-233 amt P Ammonium transporter
OBOLLGII_02753 1.4e-295 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OBOLLGII_02754 4.6e-123 citT T response regulator
OBOLLGII_02755 1.2e-247 citH C Citrate transporter
OBOLLGII_02756 3.8e-182 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OBOLLGII_02757 0.0 helD 3.6.4.12 L DNA helicase
OBOLLGII_02760 6.8e-209 L Transposase
OBOLLGII_02761 1.1e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_02762 2.2e-19
OBOLLGII_02765 3.8e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OBOLLGII_02766 4.1e-147 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
OBOLLGII_02767 5.8e-288 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OBOLLGII_02768 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OBOLLGII_02769 1.5e-212 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OBOLLGII_02770 1.1e-121 K COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
OBOLLGII_02771 1.3e-23 ymbI L Transposase
OBOLLGII_02772 1.4e-105 S HTH-like domain
OBOLLGII_02774 1.6e-123 ric D Di-iron-containing protein involved in the repair of iron-sulfur clusters
OBOLLGII_02775 2.6e-89 S Belongs to the UPF0312 family
OBOLLGII_02776 1.1e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OBOLLGII_02778 2.3e-187 T HD domain
OBOLLGII_02780 2.3e-278 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
OBOLLGII_02782 0.0 ydaO E amino acid
OBOLLGII_02783 1.4e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OBOLLGII_02784 3e-24 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OBOLLGII_02785 1.1e-173 ydbI S AI-2E family transporter
OBOLLGII_02786 4.9e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OBOLLGII_02788 1.2e-135 glnH ET Belongs to the bacterial solute-binding protein 3 family
OBOLLGII_02789 4e-108 gluC P ABC transporter
OBOLLGII_02790 9.6e-116 glnP P ABC transporter
OBOLLGII_02791 1.3e-69 K helix_turn_helix gluconate operon transcriptional repressor
OBOLLGII_02792 4.6e-194 S Protein of unknown function (DUF1648)
OBOLLGII_02793 2.4e-53 yodB K transcriptional
OBOLLGII_02794 5.7e-228 S SNARE associated Golgi protein
OBOLLGII_02795 5.3e-99 yngC S membrane-associated protein
OBOLLGII_02796 6e-153 msrR K COG1316 Transcriptional regulator
OBOLLGII_02799 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OBOLLGII_02800 0.0 metH 2.1.1.13 E Methionine synthase
OBOLLGII_02802 1.6e-09 csbD S Belongs to the UPF0337 (CsbD) family
OBOLLGII_02804 1.5e-88 K ComK protein
OBOLLGII_02805 3.2e-96 sigS 2.7.7.6 K Belongs to the sigma-70 factor family. ECF subfamily
OBOLLGII_02806 2.5e-144 E lipolytic protein G-D-S-L family
OBOLLGII_02807 1.5e-119 ywqC M biosynthesis protein
OBOLLGII_02808 1.2e-111 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
OBOLLGII_02809 1.2e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
OBOLLGII_02810 8.9e-159 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OBOLLGII_02811 5.8e-89 cpsE M Bacterial sugar transferase
OBOLLGII_02812 2.3e-92 2.4.1.21 GT4,GT5 G Glycosyl transferase 4-like
OBOLLGII_02813 1.6e-20 I CDP-alcohol phosphatidyltransferase
OBOLLGII_02814 1.5e-35 GT2 M transferase activity, transferring glycosyl groups
OBOLLGII_02815 1.1e-54 M Glycosyltransferase like family 2
OBOLLGII_02816 4.3e-147 cps1C S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OBOLLGII_02817 5e-63
OBOLLGII_02818 8.2e-171 L Transposase, IS4 family protein
OBOLLGII_02819 2.2e-72 L Transposase, IS4 family protein
OBOLLGII_02820 3e-248 L PFAM Transposase, IS4-like
OBOLLGII_02821 4.9e-157 L PFAM Transposase, IS4-like
OBOLLGII_02822 4.1e-195 L Domain of unknown function (DUF4277)
OBOLLGII_02823 1.2e-103 L Domain of unknown function (DUF4277)
OBOLLGII_02824 8.7e-63 L PFAM Transposase, IS4-like
OBOLLGII_02825 0.0 M Non-essential cell division protein that could be required for efficient cell constriction
OBOLLGII_02826 3.2e-59 croE S Helix-turn-helix
OBOLLGII_02827 3.5e-135 E IrrE N-terminal-like domain
OBOLLGII_02828 1.1e-38
OBOLLGII_02829 4.1e-78 yicJ G MFS/sugar transport protein
OBOLLGII_02830 2.2e-154 yicJ G MFS/sugar transport protein
OBOLLGII_02831 1.5e-299 2.7.1.12, 2.7.1.17 G xylulose kinase
OBOLLGII_02833 3.6e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OBOLLGII_02834 1.6e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OBOLLGII_02835 5.2e-178 3.1.1.5 I Alpha beta hydrolase
OBOLLGII_02837 0.0 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OBOLLGII_02839 1.9e-29 yodI
OBOLLGII_02840 3.4e-146 yjaZ O Zn-dependent protease
OBOLLGII_02841 3.2e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_02842 1.6e-210 L Transposase
OBOLLGII_02843 2.1e-12 yodH Q Methyltransferase
OBOLLGII_02844 7.3e-66 yodH Q Methyltransferase
OBOLLGII_02845 0.0 gtfC 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
OBOLLGII_02846 2.1e-162 S HipA-like C-terminal domain
OBOLLGII_02847 1.6e-145 S HIRAN domain
OBOLLGII_02848 6e-67 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
OBOLLGII_02850 3.2e-178 1.13.12.16, 1.3.1.9 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OBOLLGII_02851 5.4e-67 yjbR S YjbR
OBOLLGII_02852 1.9e-65 S Protein of unknown function (DUF1648)
OBOLLGII_02853 2.3e-240 L Metallo-beta-lactamase superfamily
OBOLLGII_02854 2.8e-26 S Protein of unknown function (DUF3006)
OBOLLGII_02855 0.0 L Metal dependent phosphohydrolases with conserved 'HD' motif.
OBOLLGII_02856 2.1e-42 S CRISPR-associated protein
OBOLLGII_02857 8.5e-265 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_02858 2e-45 S CRISPR-associated protein
OBOLLGII_02859 0.0 csd1 S CRISPR-associated protein (Cas_Csd1)
OBOLLGII_02860 1.6e-163 csd2 L CRISPR-associated protein Cas7
OBOLLGII_02861 5.7e-13 cmr6 L TIGRFAM CRISPR-associated RAMP protein, Cmr6 family
OBOLLGII_02863 1.6e-27
OBOLLGII_02864 0.0 ybeC E amino acid
OBOLLGII_02865 0.0 3.2.1.78 GH26 O cellulase activity
OBOLLGII_02866 2.4e-173 K cell envelope-related transcriptional attenuator
OBOLLGII_02868 2.8e-50
OBOLLGII_02869 2.1e-171 ydhF S Oxidoreductase
OBOLLGII_02870 2e-150 S transposase or invertase
OBOLLGII_02871 7.6e-17 S transposase or invertase
OBOLLGII_02872 1.1e-33 C acyl-CoA transferases carnitine dehydratase
OBOLLGII_02873 6.5e-182 yfmJ S N-terminal domain of oxidoreductase
OBOLLGII_02874 9.4e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_02875 9.2e-206 L Transposase
OBOLLGII_02876 3.3e-207 L COG3547 Transposase and inactivated derivatives
OBOLLGII_02877 3.4e-214 EGP Major facilitator Superfamily
OBOLLGII_02878 6.7e-44 2.7.1.202 K transcriptional regulator, MtlR
OBOLLGII_02879 8e-255 gph G MFS/sugar transport protein
OBOLLGII_02880 4.4e-114 K helix_turn_helix, arabinose operon control protein
OBOLLGII_02881 6.9e-74 G Glycosyl hydrolases family 39
OBOLLGII_02882 1.5e-166 ydjE EGP Major facilitator superfamily
OBOLLGII_02884 1.4e-289 L Transposase
OBOLLGII_02886 1.4e-289 L Transposase
OBOLLGII_02887 1.6e-19 ydjE EGP Major facilitator superfamily
OBOLLGII_02888 4.2e-74 K transcriptional
OBOLLGII_02889 3e-210 EGP Major facilitator Superfamily
OBOLLGII_02890 1.7e-179 K Transcriptional regulator
OBOLLGII_02892 0.0 bga2 3.2.1.23 G beta-galactosidase
OBOLLGII_02894 2e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OBOLLGII_02895 1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OBOLLGII_02896 3.4e-115 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OBOLLGII_02897 4.4e-211 opuCA E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OBOLLGII_02898 8.5e-96 yvbF K Belongs to the GbsR family
OBOLLGII_02899 1e-96 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
OBOLLGII_02900 2.1e-37 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OBOLLGII_02901 6.9e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OBOLLGII_02902 3.2e-46
OBOLLGII_02903 2.6e-111 yjlB S Cupin domain
OBOLLGII_02904 6.9e-150 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
OBOLLGII_02905 6.5e-136 yflN_1 S Metallo-beta-lactamase superfamily
OBOLLGII_02906 4.7e-51 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OBOLLGII_02907 5.7e-302 comM O Mg chelatase subunit ChlI
OBOLLGII_02908 4.1e-149 S transposase or invertase
OBOLLGII_02909 4.6e-21
OBOLLGII_02910 3.9e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OBOLLGII_02911 4.4e-208 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OBOLLGII_02912 3.2e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
OBOLLGII_02913 2.1e-304 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
OBOLLGII_02914 8e-205 nifS 2.8.1.7 E Cysteine desulfurase
OBOLLGII_02915 5.4e-144 L Transposase DDE domain
OBOLLGII_02916 1.7e-259 L Transposase DDE domain group 1
OBOLLGII_02917 5.6e-42
OBOLLGII_02918 2.6e-129 V ABC transporter
OBOLLGII_02919 1.8e-108 L PFAM Integrase, catalytic core
OBOLLGII_02920 1e-88 S NYN domain
OBOLLGII_02921 1.9e-16 focA P Formate nitrite
OBOLLGII_02922 1.5e-115 focA P Formate nitrite
OBOLLGII_02923 1.6e-149 cbiQ P COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters
OBOLLGII_02924 0.0 ykoD P ABC transporter, ATP-binding protein
OBOLLGII_02925 6.8e-93 S UPF0397 protein
OBOLLGII_02926 1.5e-163 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
OBOLLGII_02927 5.3e-59 xylS 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
OBOLLGII_02928 4.9e-295 Otg1 S Predicted membrane protein (DUF2339)
OBOLLGII_02929 2e-52
OBOLLGII_02931 9.7e-152 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
OBOLLGII_02932 3.8e-195 S Metallo-beta-lactamase superfamily
OBOLLGII_02933 3.5e-135 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OBOLLGII_02934 2.3e-134 phnE 3.6.1.63 P ABC transporter
OBOLLGII_02935 3.7e-20 phnE 3.6.1.63 P ABC transporter
OBOLLGII_02936 6.4e-11
OBOLLGII_02937 3.4e-130 U COG3267 Type II secretory pathway, component ExeA
OBOLLGII_02938 2.7e-231 L Mu transposase, C-terminal
OBOLLGII_02940 3.4e-113 phnE 3.6.1.63 P ABC transporter
OBOLLGII_02941 6.3e-171 phnD P Phosphonate ABC transporter
OBOLLGII_02942 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OBOLLGII_02943 2.1e-207 ysdC G COG1363 Cellulase M and related proteins
OBOLLGII_02944 4e-10 S double-stranded DNA endodeoxyribonuclease activity
OBOLLGII_02945 3e-12 S double-stranded DNA endodeoxyribonuclease activity
OBOLLGII_02946 2.3e-21 S Zinc-ribbon containing domain
OBOLLGII_02947 6.3e-299 yvfH C L-lactate permease
OBOLLGII_02948 6.9e-122 yvfI K COG2186 Transcriptional regulators
OBOLLGII_02949 1.8e-228 lysN EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OBOLLGII_02950 7e-62
OBOLLGII_02952 2.2e-168 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OBOLLGII_02953 5.2e-202 EGP Major facilitator Superfamily
OBOLLGII_02955 2.2e-16 S YvrJ protein family
OBOLLGII_02956 9.8e-11 S Protein of unknown function (DUF2922)
OBOLLGII_02957 2.6e-11 S Protein of unknown function (DUF1659)
OBOLLGII_02958 0.0 O Belongs to the peptidase S8 family
OBOLLGII_02959 6.6e-69 S Protein of unknown function (DUF2512)
OBOLLGII_02960 3.1e-52 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
OBOLLGII_02961 6.9e-53 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
OBOLLGII_02962 3.7e-12
OBOLLGII_02963 2.5e-288 L Transposase
OBOLLGII_02964 3.7e-249 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OBOLLGII_02965 3.9e-289 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OBOLLGII_02966 5.6e-265 L Transposase, IS4 family protein
OBOLLGII_02967 0.0 2.7.1.202 K transcriptional regulator, MtlR
OBOLLGII_02968 6.6e-156 kdsA 2.5.1.55 M Belongs to the KdsA family
OBOLLGII_02969 2.5e-175 kdsD 5.3.1.13 M Belongs to the SIS family. GutQ KpsF subfamily
OBOLLGII_02970 8.4e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OBOLLGII_02971 6.7e-215 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OBOLLGII_02972 0.0 treP 2.4.1.64 GH65 G Glycoside hydrolase, family 65
OBOLLGII_02973 9.4e-147 G Binding-protein-dependent transport system inner membrane component
OBOLLGII_02974 6.5e-221 sugA G Binding-protein-dependent transport system inner membrane component
OBOLLGII_02975 3.3e-228 G Bacterial extracellular solute-binding protein
OBOLLGII_02976 8e-129 K helix_turn_helix, arabinose operon control protein
OBOLLGII_02977 2.9e-136 gumM 2.4.1.187, 2.4.1.252 GT26,GT4 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OBOLLGII_02978 9.7e-52 S Iron-sulphur cluster biosynthesis
OBOLLGII_02979 1.1e-175 yhfP 1.1.1.1 C Quinone oxidoreductase
OBOLLGII_02980 1.3e-159 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OBOLLGII_02981 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OBOLLGII_02982 5.4e-73 3.4.21.121 O Belongs to the peptidase S8 family
OBOLLGII_02983 2e-83
OBOLLGII_02984 6e-146 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OBOLLGII_02985 9.5e-29 IQ Short-chain dehydrogenase reductase sdr
OBOLLGII_02986 3e-28 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OBOLLGII_02987 7.5e-109 cyoC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OBOLLGII_02988 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OBOLLGII_02989 4.6e-158 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OBOLLGII_02990 7.5e-123 yhcW 5.4.2.6 S hydrolase
OBOLLGII_02991 3.2e-164 lytR_1 K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OBOLLGII_02992 1.3e-125 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
OBOLLGII_02993 0.0 mapA 2.4.1.8 GH65 G Glycoside hydrolase, family 65
OBOLLGII_02994 5.7e-261 G Major facilitator Superfamily
OBOLLGII_02995 4.9e-187 malR K Transcriptional regulator
OBOLLGII_02996 0.0 ppc 4.1.1.31 C Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OBOLLGII_02998 9.9e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OBOLLGII_02999 1.8e-74 yabE S 3D domain
OBOLLGII_03000 2.6e-97 relA_2 2.7.6.5, 3.1.7.2 KT HD domain
OBOLLGII_03001 0.0 pip S YhgE Pip N-terminal domain protein
OBOLLGII_03002 6.1e-263 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_03003 2.9e-48 yqgV S Thiamine-binding protein
OBOLLGII_03004 2.9e-201 pgl 3.1.1.31 G 6-phosphogluconolactonase
OBOLLGII_03005 0.0 S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OBOLLGII_03006 0.0 levR K PTS system fructose IIA component
OBOLLGII_03007 2e-83 manX 2.7.1.191 G PTS system sorbose subfamily IIB component
OBOLLGII_03008 6e-177 manL 2.7.1.191 G PTS system mannose fructose sorbose family
OBOLLGII_03009 1.5e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
OBOLLGII_03010 4.8e-168 manN G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
OBOLLGII_03011 2.9e-63 manO S Domain of unknown function (DUF956)
OBOLLGII_03012 7.8e-213 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
OBOLLGII_03013 2.9e-276 prpD 4.2.1.79 S 2-methylcitrate dehydratase
OBOLLGII_03014 1.5e-161 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OBOLLGII_03015 2.7e-85 S Heat induced stress protein YflT
OBOLLGII_03016 6.9e-265 nylA 3.5.1.4 J Belongs to the amidase family
OBOLLGII_03017 1.5e-83 M1-594 S Thiamine-binding protein
OBOLLGII_03018 3.2e-136 ssuC_1 P binding-protein-dependent transport systems inner membrane component
OBOLLGII_03019 9.8e-183 M1-596 P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OBOLLGII_03020 2.6e-135 P ABC transporter, ATP-binding protein
OBOLLGII_03021 3.1e-159 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OBOLLGII_03022 5.2e-190 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OBOLLGII_03023 5.4e-242 hom 1.1.1.3 E homoserine dehydrogenase
OBOLLGII_03024 4.2e-149 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OBOLLGII_03025 3e-16 S Protein of unknown function (DUF4064)
OBOLLGII_03026 1.7e-284 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OBOLLGII_03027 9.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OBOLLGII_03028 9.6e-48 yhdT S Sodium pantothenate symporter
OBOLLGII_03029 8e-234 panF H Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OBOLLGII_03032 1.3e-171 corA P Mg2 transporter protein CorA family protein
OBOLLGII_03033 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
OBOLLGII_03034 3.6e-197 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
OBOLLGII_03035 3.2e-76
OBOLLGII_03036 3.6e-76 lytE CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OBOLLGII_03037 5e-139 map 3.4.11.18 E Methionine aminopeptidase
OBOLLGII_03038 7.9e-100 bioY S Biotin biosynthesis protein
OBOLLGII_03039 1.7e-143 S Protein of unknown function (DUF1672)
OBOLLGII_03040 3.7e-45
OBOLLGII_03041 4.9e-129
OBOLLGII_03042 3.1e-246 L Transposase, IS4 family protein
OBOLLGII_03043 1e-151 yetF1 S membrane
OBOLLGII_03044 3.8e-28 S Protein of unknown function (DUF1657)
OBOLLGII_03045 7.4e-194 spoVAD I Stage V sporulation protein AD
OBOLLGII_03046 5.1e-25 S Protein of unknown function (DUF1657)
OBOLLGII_03047 2.2e-173 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OBOLLGII_03048 2.1e-146 aacC 2.3.1.81 V aminoglycoside
OBOLLGII_03049 3.6e-217 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OBOLLGII_03050 2.1e-70 yxiE T Belongs to the universal stress protein A family
OBOLLGII_03051 2.4e-27
OBOLLGII_03052 4e-74
OBOLLGII_03053 4.1e-225 yfkA S YfkB-like domain
OBOLLGII_03054 1.3e-62 hxlB 4.1.2.43, 5.3.1.27 M arabinose-5-phosphate isomerase activity
OBOLLGII_03055 9.2e-144 ykrA S hydrolases of the HAD superfamily
OBOLLGII_03057 1.1e-146 yvaK 3.1.1.1 S BAAT / Acyl-CoA thioester hydrolase C terminal
OBOLLGII_03058 3.5e-21 M Spore coat protein
OBOLLGII_03059 7.7e-140 I alpha/beta hydrolase fold
OBOLLGII_03060 9.5e-98 1.5.1.38 S FMN reductase
OBOLLGII_03061 2.9e-251 L PFAM transposase IS4 family protein
OBOLLGII_03062 1.2e-29 K sequence-specific DNA binding
OBOLLGII_03063 2.7e-241 yhaO L Calcineurin-like phosphoesterase superfamily domain
OBOLLGII_03064 0.0 L AAA domain
OBOLLGII_03066 8.1e-157 mmgB 1.1.1.157 I Dehydrogenase
OBOLLGII_03067 5.7e-245 yeeO V Mate efflux family protein
OBOLLGII_03070 5.7e-112 yhbD K Protein of unknown function (DUF4004)
OBOLLGII_03071 1.4e-225 yhdR 2.6.1.1 E Aminotransferase
OBOLLGII_03072 1.5e-109 proA_2 H Methyltransferase
OBOLLGII_03073 0.0 rafA 3.2.1.22 G Alpha-galactosidase
OBOLLGII_03074 2.9e-51 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OBOLLGII_03075 8.1e-276 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OBOLLGII_03077 3.5e-154 L COG2801 Transposase and inactivated derivatives
OBOLLGII_03078 2.3e-10 L COG2963 Transposase and inactivated derivatives
OBOLLGII_03079 5e-27 L COG2963 Transposase and inactivated derivatives
OBOLLGII_03080 3.3e-58 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
OBOLLGII_03081 4.7e-54 arsD S Arsenical resistance operon trans-acting repressor ArsD
OBOLLGII_03082 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
OBOLLGII_03083 1.2e-97 padR K Domain of unknown function (DUF2703)
OBOLLGII_03084 8e-191 arsB P Arsenic resistance protein
OBOLLGII_03085 2.4e-71 arsC 1.20.4.1 T Low molecular weight phosphotyrosine protein phosphatase
OBOLLGII_03086 4.4e-146 ubiE Q Methyltransferase type 11
OBOLLGII_03087 3.6e-210 M Glycosyl hydrolases family 25
OBOLLGII_03088 1.2e-166 yfhF S nucleoside-diphosphate sugar epimerase
OBOLLGII_03089 1.8e-158 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OBOLLGII_03090 1.1e-84 thiW S Thiamine-precursor transporter protein (ThiW)
OBOLLGII_03091 2e-40 yjhE S Phage tail protein
OBOLLGII_03092 3.2e-141 hel M 5'-nucleotidase, lipoprotein e(P4)
OBOLLGII_03095 1.7e-210 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OBOLLGII_03096 2.5e-35 K ArsR family transcriptional regulator
OBOLLGII_03097 4.2e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OBOLLGII_03098 1.8e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OBOLLGII_03099 8.3e-279 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OBOLLGII_03100 4.1e-200 galM 2.7.1.6, 5.1.3.3 G Converts alpha-aldose to the beta-anomer
OBOLLGII_03101 3.7e-182 K Transcriptional regulator
OBOLLGII_03103 5.1e-32 S Cold-inducible protein YdjO
OBOLLGII_03104 1.5e-14
OBOLLGII_03106 3.3e-207 L COG3547 Transposase and inactivated derivatives
OBOLLGII_03107 2.6e-163 cvfB S protein conserved in bacteria
OBOLLGII_03108 5.8e-70 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OBOLLGII_03109 3.9e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
OBOLLGII_03110 2.8e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OBOLLGII_03111 3.5e-07 yusP P Major facilitator superfamily
OBOLLGII_03112 1.2e-274 yusP P Major facilitator superfamily
OBOLLGII_03113 1.4e-214 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OBOLLGII_03114 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OBOLLGII_03115 4.3e-124 gntR1 K transcriptional
OBOLLGII_03116 3.2e-170 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OBOLLGII_03117 1e-239 NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
OBOLLGII_03118 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
OBOLLGII_03119 2.4e-168 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OBOLLGII_03120 1.1e-115 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
OBOLLGII_03121 1.3e-205 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OBOLLGII_03122 4.9e-125 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OBOLLGII_03123 2.4e-259 yfnA E amino acid
OBOLLGII_03124 1.5e-152 degV S protein conserved in bacteria
OBOLLGII_03125 1.9e-253 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OBOLLGII_03126 1.5e-132 comFC S Phosphoribosyl transferase domain
OBOLLGII_03127 2.1e-67 yvyF S flagellar protein
OBOLLGII_03128 1e-38 flgM KNU Negative regulator of flagellin synthesis
OBOLLGII_03129 5.9e-69 flgN NOU FlgN protein
OBOLLGII_03130 7.7e-286 flgK N flagellar hook-associated protein
OBOLLGII_03131 4.3e-153 flgL N Belongs to the bacterial flagellin family
OBOLLGII_03132 3.6e-76 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OBOLLGII_03133 2.4e-34 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OBOLLGII_03134 2.4e-84 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OBOLLGII_03135 5.5e-98 K Glycerol-3-phosphate responsive antiterminator
OBOLLGII_03136 8e-115 sapB S MgtC SapB transporter
OBOLLGII_03137 3.2e-155 araL 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OBOLLGII_03138 7.5e-146 G myo-inosose-2 dehydratase activity
OBOLLGII_03139 1.5e-245 EGP Sugar (and other) transporter
OBOLLGII_03141 1.3e-169 E COG1113 Gamma-aminobutyrate permease and related permeases
OBOLLGII_03142 0.0 ycbZ 3.4.21.53 O AAA domain
OBOLLGII_03144 3.2e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_03145 5e-60 L PFAM Transposase, IS4-like
OBOLLGII_03146 8.3e-70 L PFAM Transposase, IS4-like
OBOLLGII_03147 6.4e-11
OBOLLGII_03148 3.4e-130 U COG3267 Type II secretory pathway, component ExeA
OBOLLGII_03149 2.7e-231 L Mu transposase, C-terminal
OBOLLGII_03151 4.8e-61 L PFAM Transposase, IS4-like
OBOLLGII_03152 9.6e-211 L Transposase
OBOLLGII_03153 3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OBOLLGII_03155 7.8e-61 flaG N flagellar protein FlaG
OBOLLGII_03156 0.0 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OBOLLGII_03157 1.1e-68 fliS N flagellar protein FliS
OBOLLGII_03158 7.9e-55 fliT S bacterial-type flagellum organization
OBOLLGII_03159 1.3e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OBOLLGII_03160 1.2e-306 ggtA 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OBOLLGII_03161 1.1e-15 S Ribbon-helix-helix protein, copG family
OBOLLGII_03162 1.5e-208 L Transposase
OBOLLGII_03163 1.4e-262 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_03164 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OBOLLGII_03165 2.3e-168 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OBOLLGII_03166 4.7e-157 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
OBOLLGII_03167 5.5e-50 cccB C COG2010 Cytochrome c, mono- and diheme variants
OBOLLGII_03168 9.3e-124 ftsE D cell division ATP-binding protein FtsE
OBOLLGII_03169 4.5e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OBOLLGII_03170 5.5e-96 D peptidase
OBOLLGII_03171 6.2e-271 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OBOLLGII_03172 4.3e-247 metY 2.5.1.49 E O-acetylhomoserine
OBOLLGII_03173 2.8e-182 1.1.1.3 E homoserine dehydrogenase
OBOLLGII_03174 3.5e-266 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
OBOLLGII_03175 1.1e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OBOLLGII_03176 3.9e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OBOLLGII_03177 4.1e-162 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OBOLLGII_03178 6.2e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
OBOLLGII_03179 3.8e-168 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
OBOLLGII_03180 5.4e-39 fdxA C 4Fe-4S binding domain
OBOLLGII_03181 4.9e-244 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_03182 6.3e-49 S Family of unknown function (DUF5316)
OBOLLGII_03183 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OBOLLGII_03184 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
OBOLLGII_03186 2e-258 hemY2 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OBOLLGII_03187 5.5e-161 pstS P Phosphate
OBOLLGII_03188 1.4e-157 pstC P probably responsible for the translocation of the substrate across the membrane
OBOLLGII_03189 4.8e-157 pstA P Phosphate transport system permease
OBOLLGII_03190 2.1e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OBOLLGII_03191 6e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OBOLLGII_03192 2.5e-30 S EamA-like transporter family
OBOLLGII_03193 1.4e-118 yfbR S HD containing hydrolase-like enzyme
OBOLLGII_03194 2.4e-34 csbA S protein conserved in bacteria
OBOLLGII_03195 1.6e-09 S Uncharacterized conserved protein (DUF2164)
OBOLLGII_03196 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OBOLLGII_03197 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OBOLLGII_03198 2.8e-72 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OBOLLGII_03199 2.4e-228 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OBOLLGII_03200 7.8e-145 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OBOLLGII_03201 4.2e-164 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OBOLLGII_03202 3.1e-75 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OBOLLGII_03203 5.9e-79 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OBOLLGII_03204 3.9e-53 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OBOLLGII_03205 1.9e-288 L Transposase
OBOLLGII_03206 4.3e-24 L Archaeal putative transposase ISC1217
OBOLLGII_03207 1.3e-25 L Archaeal putative transposase ISC1217
OBOLLGII_03209 1.2e-47 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OBOLLGII_03210 2.8e-72 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OBOLLGII_03211 1.9e-90 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OBOLLGII_03212 4.1e-194 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OBOLLGII_03213 4.9e-108 tagG GM Transport permease protein
OBOLLGII_03214 1.4e-138 M Glycosyltransferase like family 2
OBOLLGII_03215 4.4e-171 yvlB S Putative adhesin
OBOLLGII_03216 3.5e-31 yvlD S Membrane
OBOLLGII_03217 2.8e-171 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OBOLLGII_03218 9.2e-155 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OBOLLGII_03219 2.8e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OBOLLGII_03220 6.8e-71 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
OBOLLGII_03221 3.4e-251 S COG0457 FOG TPR repeat
OBOLLGII_03222 3.1e-178 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OBOLLGII_03223 5.1e-86 yvcI 3.6.1.55 F Nudix hydrolase
OBOLLGII_03224 1.8e-167 rapZ S Displays ATPase and GTPase activities
OBOLLGII_03225 8.5e-179 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OBOLLGII_03226 2e-172 whiA K May be required for sporulation
OBOLLGII_03227 4.3e-40 crh G Phosphocarrier protein Chr
OBOLLGII_03228 8.3e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OBOLLGII_03230 1.7e-147 S transposase or invertase
OBOLLGII_03231 1.3e-15 S transposase or invertase
OBOLLGII_03232 4.4e-18 S transposase or invertase
OBOLLGII_03233 3.2e-264 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OBOLLGII_03234 3.4e-29 sspB S spore protein
OBOLLGII_03235 3.8e-204 msmK P Belongs to the ABC transporter superfamily
OBOLLGII_03236 3.4e-166 lrp QT PucR C-terminal helix-turn-helix domain
OBOLLGII_03237 5.3e-228 HJ COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)
OBOLLGII_03238 1.7e-270 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OBOLLGII_03240 4.9e-212 yheC HJ YheC/D like ATP-grasp
OBOLLGII_03241 7.8e-260 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OBOLLGII_03242 6.5e-207 yheB S Belongs to the UPF0754 family
OBOLLGII_03243 3.9e-54 yheA S Belongs to the UPF0342 family
OBOLLGII_03244 2.7e-160 yhaX S hydrolases of the HAD superfamily
OBOLLGII_03245 6.4e-137 yhaR 5.3.3.18 I enoyl-CoA hydratase
OBOLLGII_03246 1.7e-27 S YhzD-like protein
OBOLLGII_03247 8.1e-121 P Integral membrane protein TerC family
OBOLLGII_03248 3.3e-145 ycgR S permeases
OBOLLGII_03249 5.3e-153 ycgQ S membrane
OBOLLGII_03250 6.5e-248 yhaO L DNA repair exonuclease
OBOLLGII_03251 0.0 L AAA domain
OBOLLGII_03252 1.1e-178 yhaM L Shows a 3'-5' exoribonuclease activity
OBOLLGII_03253 3e-27 yhaL S Sporulation protein YhaL
OBOLLGII_03254 6.2e-149 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OBOLLGII_03257 1.1e-53 yhaI S Protein of unknown function (DUF1878)
OBOLLGII_03258 7.5e-103 hpr K Negative regulator of protease production and sporulation
OBOLLGII_03259 2.1e-18 yhaH S YtxH-like protein
OBOLLGII_03260 9.4e-84 trpP S Tryptophan transporter TrpP
OBOLLGII_03261 4.1e-74 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OBOLLGII_03262 2.5e-138 ecsA V transporter (ATP-binding protein)
OBOLLGII_03263 7.2e-220 ecsB U ABC transporter
OBOLLGII_03264 3.7e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OBOLLGII_03265 2.3e-238 yhfA C membrane
OBOLLGII_03267 6.3e-93 traP 1.14.99.57 S enzyme involved in biosynthesis of extracellular polysaccharides
OBOLLGII_03268 4.3e-197 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OBOLLGII_03269 2.7e-182 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OBOLLGII_03270 1.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OBOLLGII_03271 8.3e-102 yhgD K Transcriptional regulator
OBOLLGII_03272 1.7e-149 yhgE S YhgE Pip N-terminal domain protein
OBOLLGII_03273 5.1e-59 EGP Major facilitator Superfamily
OBOLLGII_03274 2e-164 EG EamA-like transporter family
OBOLLGII_03275 4.1e-18 aldA 1.2.1.21, 1.2.1.22 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OBOLLGII_03276 5e-26 aldA 1.2.1.21, 1.2.1.22 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OBOLLGII_03277 1.7e-102 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OBOLLGII_03278 4e-63 ytkA S YtkA-like
OBOLLGII_03279 3e-21 yhfH S YhfH-like protein
OBOLLGII_03280 3.2e-186 lplJ 6.3.1.20 H Lipoate-protein ligase
OBOLLGII_03281 2.8e-293 fadD 6.2.1.3 IQ Activates fatty acids by binding to coenzyme A
OBOLLGII_03282 7.9e-118 azlC E AzlC protein
OBOLLGII_03283 5.7e-41 azlD S branched-chain amino acid
OBOLLGII_03284 2.2e-208 yhfN 3.4.24.84 O Peptidase M48
OBOLLGII_03285 1.7e-08 S IDEAL
OBOLLGII_03286 8.2e-96 comK K Competence transcription factor
OBOLLGII_03287 1.2e-143 S Mitochondrial biogenesis AIM24
OBOLLGII_03288 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
OBOLLGII_03289 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OBOLLGII_03290 4.7e-29 gerPF S Spore germination protein gerPA/gerPF
OBOLLGII_03291 8.4e-70 gerPE S Spore germination protein GerPE
OBOLLGII_03292 2e-25 gerPD S Spore germination protein
OBOLLGII_03293 8e-98 gerPC S Spore germination protein
OBOLLGII_03294 3e-31 gerPA S Spore germination protein
OBOLLGII_03295 6.4e-226 P Protein of unknown function (DUF418)
OBOLLGII_03296 2.3e-167 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OBOLLGII_03297 3.3e-59 yisL S UPF0344 protein
OBOLLGII_03298 6.6e-104 yisN S Protein of unknown function (DUF2777)
OBOLLGII_03299 5.5e-158 yitS S protein conserved in bacteria
OBOLLGII_03300 6.3e-25 S Protein of unknown function (DUF3813)
OBOLLGII_03301 1.1e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
OBOLLGII_03302 9.5e-52 yitW S metal-sulfur cluster biosynthetic enzyme
OBOLLGII_03303 6.8e-26 yjzC S YjzC-like protein
OBOLLGII_03304 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
OBOLLGII_03306 3.9e-147 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
OBOLLGII_03308 6.1e-263 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_03309 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OBOLLGII_03310 6.2e-235 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OBOLLGII_03311 2.3e-150 yjaZ O Zn-dependent protease
OBOLLGII_03312 7.8e-191 oppD P Belongs to the ABC transporter superfamily
OBOLLGII_03313 1.3e-176 oppF P Belongs to the ABC transporter superfamily
OBOLLGII_03314 1.7e-168 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OBOLLGII_03315 4.5e-134 oppC EP binding-protein-dependent transport systems inner membrane component
OBOLLGII_03316 0.0 oppA1 E COG0747 ABC-type dipeptide transport system, periplasmic component
OBOLLGII_03317 1.1e-146 yjbA S Belongs to the UPF0736 family
OBOLLGII_03318 1e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OBOLLGII_03319 8.3e-49 S Domain of unknown function (DUF3899)
OBOLLGII_03320 6.1e-263 S PFAM Uncharacterised protein family UPF0236
OBOLLGII_03321 1.5e-300 dppE_1 E ABC transporter substrate-binding protein
OBOLLGII_03322 4.4e-153 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OBOLLGII_03323 1.2e-180 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OBOLLGII_03324 1.5e-197 oppD P Belongs to the ABC transporter superfamily
OBOLLGII_03325 3e-173 oppF E Belongs to the ABC transporter superfamily
OBOLLGII_03326 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OBOLLGII_03327 1.7e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OBOLLGII_03328 2.6e-226 yjbF S Competence protein
OBOLLGII_03329 0.0 pepF E oligoendopeptidase F
OBOLLGII_03331 1.2e-160 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OBOLLGII_03332 4.4e-73 yjbI S COG2346 Truncated hemoglobins
OBOLLGII_03333 4.5e-98 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OBOLLGII_03334 1.1e-101 yjbK S protein conserved in bacteria
OBOLLGII_03335 4.9e-66 yjbL S Belongs to the UPF0738 family
OBOLLGII_03336 9.4e-121 yjbM 2.7.6.5 S GTP pyrophosphokinase
OBOLLGII_03337 4.9e-153 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OBOLLGII_03338 1.5e-163 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OBOLLGII_03339 3.1e-138 prpE 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OBOLLGII_03340 7.3e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OBOLLGII_03342 1.6e-06 yjbX S Spore coat protein CotO
OBOLLGII_03343 3.9e-83 cotY S Spore coat protein
OBOLLGII_03344 8.4e-60 S Protein of unknown function (DUF1360)
OBOLLGII_03346 3.6e-79 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OBOLLGII_03347 1.6e-82 spoVAC S stage V sporulation protein AC
OBOLLGII_03348 5.1e-187 spoVAD I Stage V sporulation protein AD
OBOLLGII_03349 3.3e-56 spoVAE S stage V sporulation protein
OBOLLGII_03351 4.5e-39 spoVIF S Stage VI sporulation protein F
OBOLLGII_03353 2.3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OBOLLGII_03354 2.4e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
OBOLLGII_03355 2.1e-134 yjcH P COG2382 Enterochelin esterase and related enzymes
OBOLLGII_03361 4.6e-168 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
OBOLLGII_03362 4.1e-78 IQ Enoyl-(Acyl carrier protein) reductase
OBOLLGII_03363 2e-166 yhaQ S ABC transporter, ATP-binding protein
OBOLLGII_03364 2.6e-209 yhaP CP COG1668 ABC-type Na efflux pump, permease component
OBOLLGII_03365 4.7e-257 pepC 3.4.22.40 E Papain family cysteine protease
OBOLLGII_03366 0.0 pepF2 E COG1164 Oligoendopeptidase F
OBOLLGII_03367 7e-34 ykuS S Belongs to the UPF0180 family
OBOLLGII_03368 0.0 6.2.1.1, 6.2.1.16 I AMP-dependent synthetase
OBOLLGII_03369 9e-90 ywrA P COG2059 Chromate transport protein ChrA
OBOLLGII_03370 5.9e-98 chrA P Chromate transporter
OBOLLGII_03371 3.6e-82 ywrC K Transcriptional regulator
OBOLLGII_03372 1.4e-37 L Belongs to the 'phage' integrase family
OBOLLGII_03374 4.7e-144 pocR K Sensory domain found in PocR
OBOLLGII_03375 1.8e-223 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OBOLLGII_03376 1.2e-210 yxjG 2.1.1.14 E Methionine synthase
OBOLLGII_03377 7.7e-231 esaA S domain protein
OBOLLGII_03379 4.4e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
OBOLLGII_03380 1.5e-218 essB S WXG100 protein secretion system (Wss), protein YukC
OBOLLGII_03381 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OBOLLGII_03382 1.3e-23 ymbI L Transposase
OBOLLGII_03383 1.4e-105 S HTH-like domain
OBOLLGII_03384 1e-151 yetF1 S membrane
OBOLLGII_03385 3.8e-28 S Protein of unknown function (DUF1657)
OBOLLGII_03386 3e-56 spoVAD I Stage V sporulation protein AD
OBOLLGII_03387 1.7e-259 L Transposase DDE domain group 1
OBOLLGII_03388 1.1e-127 spoVAD I Stage V sporulation protein AD
OBOLLGII_03389 5.1e-25 S Protein of unknown function (DUF1657)
OBOLLGII_03390 3e-255 L Transposase, IS4 family protein
OBOLLGII_03392 2.6e-175 ldhA 1.1.1.28 CH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
OBOLLGII_03393 3.1e-246 proP EGP Transporter
OBOLLGII_03394 6.4e-142 tesE Q COG3971 2-keto-4-pentenoate hydratase
OBOLLGII_03395 3.9e-75 nsrR K Transcriptional regulator
OBOLLGII_03396 9e-231 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OBOLLGII_03397 1.6e-124 S membrane transporter protein
OBOLLGII_03398 4e-75 dps P Ferritin-like domain
OBOLLGII_03399 2.6e-180 mocA S Oxidoreductase
OBOLLGII_03400 1.1e-206 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
OBOLLGII_03401 4.3e-302 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OBOLLGII_03402 6.7e-81
OBOLLGII_03403 2.1e-127 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OBOLLGII_03404 8.1e-28 sspD S small acid-soluble spore protein
OBOLLGII_03405 4.3e-19 S Stage 0 Sporulation Regulatory protein
OBOLLGII_03407 7.7e-288 kinE 2.7.13.3 T Histidine kinase
OBOLLGII_03408 4e-78 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OBOLLGII_03409 4.3e-71 XK27_09985 S Protein of unknown function (DUF1232)
OBOLLGII_03411 0.0 clpE O Belongs to the ClpA ClpB family
OBOLLGII_03412 1.1e-179 ykvI S membrane
OBOLLGII_03413 7.3e-104 S Abortive infection protein
OBOLLGII_03414 4.2e-26 ykvS S protein conserved in bacteria
OBOLLGII_03415 5e-26
OBOLLGII_03416 3.2e-40 ptsH G phosphocarrier protein HPr
OBOLLGII_03417 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OBOLLGII_03418 1.1e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OBOLLGII_03419 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OBOLLGII_03420 4.4e-219 patA 2.6.1.1 E Aminotransferase
OBOLLGII_03421 6.4e-165 cheV 2.7.13.3 T Chemotaxis protein CheV
OBOLLGII_03422 2.6e-85 ykyB S YkyB-like protein
OBOLLGII_03423 0.0 ydgH S drug exporters of the RND superfamily
OBOLLGII_03424 3e-16 T Diguanylate cyclase
OBOLLGII_03425 1e-32 T Diguanylate cyclase
OBOLLGII_03426 1e-31
OBOLLGII_03427 9.3e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OBOLLGII_03428 6.7e-162 3.5.1.4 C Acetamidase
OBOLLGII_03429 5.8e-39 ykuJ S protein conserved in bacteria
OBOLLGII_03430 6.5e-78 ykuL S CBS domain
OBOLLGII_03431 3.4e-56 ccpC K Transcriptional regulator

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)