ORF_ID e_value Gene_name EC_number CAZy COGs Description
BBKJAIEB_00001 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BBKJAIEB_00002 4.8e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
BBKJAIEB_00003 1.1e-29 yyzM S Protein conserved in bacteria
BBKJAIEB_00004 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
BBKJAIEB_00005 7.5e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
BBKJAIEB_00006 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBKJAIEB_00007 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
BBKJAIEB_00008 2.7e-61 divIC D Septum formation initiator
BBKJAIEB_00010 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
BBKJAIEB_00011 5.5e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
BBKJAIEB_00012 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
BBKJAIEB_00013 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBKJAIEB_00014 3e-30
BBKJAIEB_00015 5.4e-133 L Transposase
BBKJAIEB_00016 1.9e-46 L transposase activity
BBKJAIEB_00017 5.7e-23 L Transposase
BBKJAIEB_00018 2.7e-28 L transposition
BBKJAIEB_00019 4.3e-96 L Transposase and inactivated derivatives
BBKJAIEB_00023 5.3e-11
BBKJAIEB_00028 2.8e-138 mreC M Involved in formation and maintenance of cell shape
BBKJAIEB_00029 1.4e-87 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BBKJAIEB_00030 4.4e-86 usp 3.5.1.28 CBM50 S CHAP domain
BBKJAIEB_00031 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBKJAIEB_00032 6.5e-218 araT 2.6.1.1 E Aminotransferase
BBKJAIEB_00033 7e-144 recO L Involved in DNA repair and RecF pathway recombination
BBKJAIEB_00034 2.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BBKJAIEB_00035 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBKJAIEB_00036 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
BBKJAIEB_00037 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBKJAIEB_00038 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BBKJAIEB_00039 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
BBKJAIEB_00040 2e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBKJAIEB_00041 3.1e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
BBKJAIEB_00042 5.7e-48 L transposition
BBKJAIEB_00043 9.5e-53 L transposition
BBKJAIEB_00044 1.4e-33 L Integrase core domain protein
BBKJAIEB_00045 1.2e-160 S CHAP domain
BBKJAIEB_00046 2.6e-241 purD 6.3.4.13 F Belongs to the GARS family
BBKJAIEB_00047 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBKJAIEB_00048 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BBKJAIEB_00049 6e-140 1.1.1.169 H Ketopantoate reductase
BBKJAIEB_00050 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBKJAIEB_00051 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
BBKJAIEB_00052 8.2e-70 argR K Regulates arginine biosynthesis genes
BBKJAIEB_00053 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
BBKJAIEB_00054 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBKJAIEB_00055 1.3e-35 S Protein of unknown function (DUF3021)
BBKJAIEB_00056 6.2e-51 KT phosphorelay signal transduction system
BBKJAIEB_00058 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BBKJAIEB_00060 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
BBKJAIEB_00061 1.4e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
BBKJAIEB_00062 2.9e-232 cinA 3.5.1.42 S Belongs to the CinA family
BBKJAIEB_00063 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BBKJAIEB_00064 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
BBKJAIEB_00068 5.3e-11
BBKJAIEB_00071 1.9e-07
BBKJAIEB_00076 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBKJAIEB_00077 5.6e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
BBKJAIEB_00078 5.5e-36 XK27_02060 S Transglycosylase associated protein
BBKJAIEB_00079 1.8e-26 badR K DNA-binding transcription factor activity
BBKJAIEB_00080 1.5e-50 S reductase
BBKJAIEB_00081 7.5e-37 S reductase
BBKJAIEB_00083 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
BBKJAIEB_00084 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BBKJAIEB_00085 9.3e-83 S Putative small multi-drug export protein
BBKJAIEB_00086 6.2e-76 ctsR K Belongs to the CtsR family
BBKJAIEB_00087 0.0 clpC O Belongs to the ClpA ClpB family
BBKJAIEB_00088 2.5e-129 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BBKJAIEB_00089 4.3e-58 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BBKJAIEB_00090 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
BBKJAIEB_00091 6.6e-114 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
BBKJAIEB_00092 3.4e-270 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
BBKJAIEB_00093 1.7e-142 S SseB protein N-terminal domain
BBKJAIEB_00094 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
BBKJAIEB_00095 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
BBKJAIEB_00096 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BBKJAIEB_00099 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBKJAIEB_00100 7e-92 yacP S RNA-binding protein containing a PIN domain
BBKJAIEB_00101 3.7e-154 degV S DegV family
BBKJAIEB_00102 1.7e-13 K PFAM helix-turn-helix domain protein
BBKJAIEB_00103 3.2e-33 K helix-turn-helix
BBKJAIEB_00104 3.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BBKJAIEB_00105 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBKJAIEB_00106 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
BBKJAIEB_00107 4.1e-36 K sequence-specific DNA binding
BBKJAIEB_00109 6.8e-78 S Lantibiotic dehydratase, C terminus
BBKJAIEB_00110 0.0 S Lantibiotic dehydratase, C terminus
BBKJAIEB_00111 9.5e-231 spaC2 V Lanthionine synthetase C family protein
BBKJAIEB_00112 1.7e-65 EGP Major facilitator Superfamily
BBKJAIEB_00113 4.2e-104 EGP Major facilitator Superfamily
BBKJAIEB_00114 1.1e-120
BBKJAIEB_00115 3.9e-25 isp2 S pathogenesis
BBKJAIEB_00116 3.1e-37 isp2 S pathogenesis
BBKJAIEB_00117 5.7e-91 tnp L Transposase
BBKJAIEB_00118 2e-142 capA M Bacterial capsule synthesis protein
BBKJAIEB_00119 2.5e-58 capA M Bacterial capsule synthesis protein
BBKJAIEB_00120 6.1e-39 gcvR T UPF0237 protein
BBKJAIEB_00121 8.7e-243 XK27_08635 S UPF0210 protein
BBKJAIEB_00122 2e-134 ais G Phosphoglycerate mutase
BBKJAIEB_00123 5.7e-141 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
BBKJAIEB_00124 1.5e-101 acmA 3.2.1.17 NU amidase activity
BBKJAIEB_00125 6.9e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BBKJAIEB_00126 5.7e-70 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BBKJAIEB_00127 7.5e-298 dnaK O Heat shock 70 kDa protein
BBKJAIEB_00128 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BBKJAIEB_00129 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
BBKJAIEB_00130 3.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
BBKJAIEB_00131 1e-71 hmpT S cog cog4720
BBKJAIEB_00133 0.0 amiA E ABC transporter, substrate-binding protein, family 5
BBKJAIEB_00134 1.1e-159 L Transposase
BBKJAIEB_00135 9.9e-19 S Domain of unknown function (DUF4649)
BBKJAIEB_00136 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
BBKJAIEB_00137 5.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
BBKJAIEB_00138 8.5e-87
BBKJAIEB_00139 1.6e-77 sigH K DNA-templated transcription, initiation
BBKJAIEB_00140 1e-148 ykuT M mechanosensitive ion channel
BBKJAIEB_00141 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BBKJAIEB_00142 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
BBKJAIEB_00143 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
BBKJAIEB_00144 1.4e-83 XK27_03960 S Protein of unknown function (DUF3013)
BBKJAIEB_00145 3.1e-80 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
BBKJAIEB_00146 2.6e-177 prmA J Ribosomal protein L11 methyltransferase
BBKJAIEB_00147 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
BBKJAIEB_00148 5.5e-30 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BBKJAIEB_00149 3.6e-86 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BBKJAIEB_00150 7.6e-46 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BBKJAIEB_00151 9.5e-144 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BBKJAIEB_00152 1.5e-33 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
BBKJAIEB_00153 5.3e-83 nrdI F Belongs to the NrdI family
BBKJAIEB_00154 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBKJAIEB_00155 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BBKJAIEB_00156 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
BBKJAIEB_00157 2.8e-26 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
BBKJAIEB_00158 1.7e-63 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
BBKJAIEB_00159 8.7e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
BBKJAIEB_00160 2.1e-14 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBKJAIEB_00161 5.1e-212 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBKJAIEB_00162 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BBKJAIEB_00163 1.7e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
BBKJAIEB_00164 4.6e-200 yhjX P Major Facilitator
BBKJAIEB_00165 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BBKJAIEB_00166 5e-94 V VanZ like family
BBKJAIEB_00169 1.7e-123 glnQ E abc transporter atp-binding protein
BBKJAIEB_00170 1.5e-275 glnP P ABC transporter
BBKJAIEB_00171 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
BBKJAIEB_00172 8.8e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BBKJAIEB_00173 1.9e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
BBKJAIEB_00174 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
BBKJAIEB_00175 1.4e-234 sufD O assembly protein SufD
BBKJAIEB_00176 1.5e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBKJAIEB_00177 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
BBKJAIEB_00178 2.2e-273 sufB O assembly protein SufB
BBKJAIEB_00179 1.6e-18 oppA E ABC transporter substrate-binding protein
BBKJAIEB_00180 1.4e-139 oppA E ABC transporter substrate-binding protein
BBKJAIEB_00181 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBKJAIEB_00182 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBKJAIEB_00183 3.4e-71 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBKJAIEB_00184 1.7e-58 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBKJAIEB_00185 1e-27 oppD P Belongs to the ABC transporter superfamily
BBKJAIEB_00186 2.5e-32 oppD P Belongs to the ABC transporter superfamily
BBKJAIEB_00187 1.1e-68 oppD P Belongs to the ABC transporter superfamily
BBKJAIEB_00188 2.6e-45 oppD P Belongs to the ABC transporter superfamily
BBKJAIEB_00189 3.8e-16 oppF P Belongs to the ABC transporter superfamily
BBKJAIEB_00190 1.3e-11 oppF P Belongs to the ABC transporter superfamily
BBKJAIEB_00191 4.3e-89 oppF P Belongs to the ABC transporter superfamily
BBKJAIEB_00193 5.1e-11
BBKJAIEB_00194 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BBKJAIEB_00195 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBKJAIEB_00196 2.6e-197 EGP Major facilitator Superfamily
BBKJAIEB_00197 3.1e-72 adcR K transcriptional
BBKJAIEB_00198 2.2e-136 adcC P ABC transporter, ATP-binding protein
BBKJAIEB_00199 4.6e-130 adcB P ABC transporter (Permease
BBKJAIEB_00200 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
BBKJAIEB_00201 6.9e-28 ptsG 2.7.1.199, 2.7.1.208 G pts system
BBKJAIEB_00202 4.3e-148 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
BBKJAIEB_00203 1.7e-82 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
BBKJAIEB_00204 1e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
BBKJAIEB_00205 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
BBKJAIEB_00206 9.4e-127 yeeN K transcriptional regulatory protein
BBKJAIEB_00207 3.7e-49 yajC U protein transport
BBKJAIEB_00208 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BBKJAIEB_00209 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
BBKJAIEB_00210 7.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
BBKJAIEB_00211 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
BBKJAIEB_00212 1.2e-165 L integrase core domain
BBKJAIEB_00213 0.0 WQ51_06230 S ABC transporter substrate binding protein
BBKJAIEB_00214 5.2e-142 cmpC S abc transporter atp-binding protein
BBKJAIEB_00215 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BBKJAIEB_00216 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
BBKJAIEB_00217 2.4e-75 L transposase activity
BBKJAIEB_00220 3e-42
BBKJAIEB_00221 3.4e-55 S TM2 domain
BBKJAIEB_00222 4e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BBKJAIEB_00223 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BBKJAIEB_00224 1.6e-24 secE U Belongs to the SecE SEC61-gamma family
BBKJAIEB_00225 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
BBKJAIEB_00226 2.8e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
BBKJAIEB_00227 6e-55 cof Q phosphatase activity
BBKJAIEB_00228 3.1e-34 cof Q phosphatase activity
BBKJAIEB_00229 4.7e-79 glcR K transcriptional regulator (DeoR family)
BBKJAIEB_00230 4.5e-38 glcR K transcriptional regulator (DeoR family)
BBKJAIEB_00231 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
BBKJAIEB_00232 7.6e-41 K transcriptional
BBKJAIEB_00233 7.4e-89 S thiolester hydrolase activity
BBKJAIEB_00234 2.2e-142 S COG1073 Hydrolases of the alpha beta superfamily
BBKJAIEB_00235 1.4e-278 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BBKJAIEB_00236 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
BBKJAIEB_00237 3.2e-77 yhaI L Membrane
BBKJAIEB_00238 6e-260 pepC 3.4.22.40 E aminopeptidase
BBKJAIEB_00239 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BBKJAIEB_00240 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
BBKJAIEB_00241 3.1e-95 ypsA S Belongs to the UPF0398 family
BBKJAIEB_00242 1.6e-49 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
BBKJAIEB_00243 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
BBKJAIEB_00244 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
BBKJAIEB_00245 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
BBKJAIEB_00246 1.4e-21
BBKJAIEB_00247 9.8e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
BBKJAIEB_00248 1.7e-81 XK27_09675 K -acetyltransferase
BBKJAIEB_00249 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BBKJAIEB_00250 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BBKJAIEB_00252 5.1e-84 L Integrase core domain protein
BBKJAIEB_00253 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BBKJAIEB_00254 2.7e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
BBKJAIEB_00255 2.5e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBKJAIEB_00256 2.3e-92 XK27_09705 6.1.1.14 S HD superfamily hydrolase
BBKJAIEB_00257 8.8e-98 ybhL S Belongs to the BI1 family
BBKJAIEB_00260 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
BBKJAIEB_00261 9.6e-92 K transcriptional regulator
BBKJAIEB_00262 7.6e-36 yneF S UPF0154 protein
BBKJAIEB_00263 3.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
BBKJAIEB_00264 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BBKJAIEB_00265 3.5e-99 XK27_09740 S Phosphoesterase
BBKJAIEB_00266 2.1e-85 ykuL S CBS domain
BBKJAIEB_00267 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
BBKJAIEB_00268 6.9e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BBKJAIEB_00269 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBKJAIEB_00270 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BBKJAIEB_00271 8e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
BBKJAIEB_00272 1.2e-258 trkH P Cation transport protein
BBKJAIEB_00273 1.5e-247 trkA P Potassium transporter peripheral membrane component
BBKJAIEB_00274 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BBKJAIEB_00275 1.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BBKJAIEB_00276 2.5e-110 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
BBKJAIEB_00277 3.3e-161 K sequence-specific DNA binding
BBKJAIEB_00278 3.6e-32 V protein secretion by the type I secretion system
BBKJAIEB_00279 4.1e-108 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BBKJAIEB_00280 1.5e-43 V protein secretion by the type I secretion system
BBKJAIEB_00281 1.8e-27 comA V protein secretion by the type I secretion system
BBKJAIEB_00282 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BBKJAIEB_00283 1.9e-44 yhaI L Membrane
BBKJAIEB_00284 2.2e-84 S Domain of unknown function (DUF4173)
BBKJAIEB_00285 6.8e-95 ureI S AmiS/UreI family transporter
BBKJAIEB_00286 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
BBKJAIEB_00287 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
BBKJAIEB_00288 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
BBKJAIEB_00289 6.6e-78 ureE O enzyme active site formation
BBKJAIEB_00290 1.2e-129 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BBKJAIEB_00291 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BBKJAIEB_00292 2e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BBKJAIEB_00293 8.7e-176 cbiM P PDGLE domain
BBKJAIEB_00294 1.1e-136 P cobalt transport protein
BBKJAIEB_00295 3.1e-130 cbiO P ABC transporter
BBKJAIEB_00296 6.8e-95 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BBKJAIEB_00297 8.7e-176 cbiM P PDGLE domain
BBKJAIEB_00298 1.1e-136 P cobalt transport protein
BBKJAIEB_00299 3.1e-130 cbiO P ABC transporter
BBKJAIEB_00300 1.1e-142 ET amino acid transport
BBKJAIEB_00301 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
BBKJAIEB_00302 6.7e-23 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
BBKJAIEB_00303 1.2e-45 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
BBKJAIEB_00304 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
BBKJAIEB_00305 6.5e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
BBKJAIEB_00306 4.4e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBKJAIEB_00307 3e-98 metI P ABC transporter (Permease
BBKJAIEB_00308 3.5e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BBKJAIEB_00309 5.2e-33 salL 2.5.1.63, 2.5.1.94 F Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
BBKJAIEB_00310 2e-109 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
BBKJAIEB_00311 8e-94 S UPF0397 protein
BBKJAIEB_00312 0.0 ykoD P abc transporter atp-binding protein
BBKJAIEB_00313 8.5e-148 cbiQ P cobalt transport
BBKJAIEB_00314 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BBKJAIEB_00315 2.3e-11 ulaG S L-ascorbate 6-phosphate lactonase
BBKJAIEB_00316 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
BBKJAIEB_00317 2.7e-244 P COG0168 Trk-type K transport systems, membrane components
BBKJAIEB_00318 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
BBKJAIEB_00319 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
BBKJAIEB_00320 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BBKJAIEB_00321 5.3e-281 T PhoQ Sensor
BBKJAIEB_00322 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBKJAIEB_00323 3.2e-217 dnaB L Replication initiation and membrane attachment
BBKJAIEB_00324 4e-167 dnaI L Primosomal protein DnaI
BBKJAIEB_00325 7.4e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
BBKJAIEB_00326 3.5e-283 P ABC transporter transmembrane region
BBKJAIEB_00327 5.5e-30 L COG2801 Transposase and inactivated derivatives
BBKJAIEB_00328 1.5e-22 L COG2801 Transposase and inactivated derivatives
BBKJAIEB_00330 6.2e-97
BBKJAIEB_00331 8.6e-34 S ABC-2 type transporter
BBKJAIEB_00332 1.6e-126 V AAA domain, putative AbiEii toxin, Type IV TA system
BBKJAIEB_00333 5e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BBKJAIEB_00334 6.5e-63 manO S protein conserved in bacteria
BBKJAIEB_00335 8.2e-168 manN G PTS system mannose fructose sorbose family IID component
BBKJAIEB_00336 7.8e-117 manM G pts system
BBKJAIEB_00337 1.1e-181 manL 2.7.1.191 G pts system
BBKJAIEB_00338 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
BBKJAIEB_00339 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
BBKJAIEB_00340 5.6e-248 pbuO S permease
BBKJAIEB_00341 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
BBKJAIEB_00342 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
BBKJAIEB_00343 5.2e-218 brpA K Transcriptional
BBKJAIEB_00344 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
BBKJAIEB_00345 3.1e-212 nusA K Participates in both transcription termination and antitermination
BBKJAIEB_00346 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
BBKJAIEB_00347 1.4e-41 ylxQ J ribosomal protein
BBKJAIEB_00348 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BBKJAIEB_00349 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BBKJAIEB_00350 2.6e-43 yvdD 3.2.2.10 S cytokinin biosynthetic process
BBKJAIEB_00351 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
BBKJAIEB_00353 1.1e-231 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
BBKJAIEB_00354 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBKJAIEB_00355 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
BBKJAIEB_00356 4.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
BBKJAIEB_00357 1.5e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
BBKJAIEB_00358 5.1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
BBKJAIEB_00360 4e-09 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
BBKJAIEB_00361 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BBKJAIEB_00362 8.3e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BBKJAIEB_00363 9.8e-74 ylbF S Belongs to the UPF0342 family
BBKJAIEB_00364 9.3e-46 ylbG S UPF0298 protein
BBKJAIEB_00365 1.5e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
BBKJAIEB_00366 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
BBKJAIEB_00367 9.2e-138 livM E Belongs to the binding-protein-dependent transport system permease family
BBKJAIEB_00368 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
BBKJAIEB_00369 6.9e-122 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
BBKJAIEB_00370 2.3e-69 acuB S IMP dehydrogenase activity
BBKJAIEB_00371 1.2e-42 acuB S IMP dehydrogenase activity
BBKJAIEB_00372 4.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BBKJAIEB_00373 1.1e-110 yvyE 3.4.13.9 S YigZ family
BBKJAIEB_00374 1.7e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BBKJAIEB_00375 3.4e-123 comFC S Competence protein
BBKJAIEB_00376 4.4e-92 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBKJAIEB_00380 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
BBKJAIEB_00381 4.1e-107 S Domain of unknown function (DUF1803)
BBKJAIEB_00382 7.8e-102 ygaC J Belongs to the UPF0374 family
BBKJAIEB_00383 2.1e-132 recX 2.4.1.337 GT4 S Regulatory protein RecX
BBKJAIEB_00384 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBKJAIEB_00385 2.3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
BBKJAIEB_00386 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
BBKJAIEB_00387 1.1e-113 S Haloacid dehalogenase-like hydrolase
BBKJAIEB_00388 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
BBKJAIEB_00389 4e-72 marR K Transcriptional regulator, MarR family
BBKJAIEB_00390 6.8e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBKJAIEB_00391 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBKJAIEB_00392 3.4e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
BBKJAIEB_00393 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
BBKJAIEB_00394 1.3e-126 IQ reductase
BBKJAIEB_00395 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
BBKJAIEB_00396 3.8e-55 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
BBKJAIEB_00397 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BBKJAIEB_00398 4.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
BBKJAIEB_00399 4.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BBKJAIEB_00400 3.3e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
BBKJAIEB_00401 1.1e-105 L COG2801 Transposase and inactivated derivatives
BBKJAIEB_00402 1.5e-37 L transposase activity
BBKJAIEB_00403 3.6e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
BBKJAIEB_00404 3.2e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
BBKJAIEB_00405 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
BBKJAIEB_00406 6.5e-72 M Glycosyltransferase sugar-binding region containing DXD motif
BBKJAIEB_00407 5.3e-29 L transposase activity
BBKJAIEB_00408 1.5e-204 rny D Endoribonuclease that initiates mRNA decay
BBKJAIEB_00409 1.8e-84 L Transposase
BBKJAIEB_00410 3.6e-113 fruR K transcriptional
BBKJAIEB_00411 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
BBKJAIEB_00412 1.1e-116 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
BBKJAIEB_00413 7.3e-140 fruA 2.7.1.202 G phosphotransferase system
BBKJAIEB_00414 1.1e-47 fruA 2.7.1.202 G phosphotransferase system
BBKJAIEB_00415 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBKJAIEB_00416 2.8e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BBKJAIEB_00418 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
BBKJAIEB_00419 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBKJAIEB_00420 3.5e-293 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
BBKJAIEB_00421 9.5e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
BBKJAIEB_00422 6.4e-29 2.3.1.128 K acetyltransferase
BBKJAIEB_00423 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
BBKJAIEB_00424 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
BBKJAIEB_00425 2.1e-123 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBKJAIEB_00426 3.8e-63 WQ51_03320 S cog cog4835
BBKJAIEB_00427 3.2e-60 XK27_08360 S EDD domain protein, DegV family
BBKJAIEB_00428 2.2e-76 XK27_08360 T EDD domain protein, DegV family
BBKJAIEB_00429 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
BBKJAIEB_00430 7.4e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BBKJAIEB_00431 0.0 yfmR S abc transporter atp-binding protein
BBKJAIEB_00432 1.6e-24 U response to pH
BBKJAIEB_00433 1.7e-69 3.6.1.13, 3.6.1.55 F Nudix family
BBKJAIEB_00434 2.7e-43 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
BBKJAIEB_00435 7.6e-82 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
BBKJAIEB_00436 1.1e-86 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
BBKJAIEB_00437 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
BBKJAIEB_00438 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
BBKJAIEB_00439 9.4e-77 K DNA-binding transcription factor activity
BBKJAIEB_00440 0.0 lmrA1 V abc transporter atp-binding protein
BBKJAIEB_00441 2.2e-97 lmrA2 V abc transporter atp-binding protein
BBKJAIEB_00442 8.1e-213 lmrA2 V abc transporter atp-binding protein
BBKJAIEB_00443 1.2e-44 K Acetyltransferase (GNAT) family
BBKJAIEB_00444 2.3e-122 sptS 2.7.13.3 T Histidine kinase
BBKJAIEB_00445 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
BBKJAIEB_00446 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BBKJAIEB_00447 1.7e-159 cvfB S Protein conserved in bacteria
BBKJAIEB_00448 7.4e-35 yozE S Belongs to the UPF0346 family
BBKJAIEB_00449 9.5e-49 usp 3.5.1.28 CBM50 S CHAP domain
BBKJAIEB_00450 1.1e-59 rlpA M LysM domain protein
BBKJAIEB_00451 8e-191 phoH T phosphate starvation-inducible protein PhoH
BBKJAIEB_00455 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBKJAIEB_00456 1.2e-166 K transcriptional regulator (lysR family)
BBKJAIEB_00457 5.3e-186 coiA 3.6.4.12 S Competence protein
BBKJAIEB_00458 0.0 pepF E oligoendopeptidase F
BBKJAIEB_00459 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
BBKJAIEB_00460 7.1e-174 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
BBKJAIEB_00461 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BBKJAIEB_00462 3.5e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
BBKJAIEB_00463 5e-92 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
BBKJAIEB_00464 3.7e-66 3.4.17.14, 3.5.1.28 NU amidase activity
BBKJAIEB_00465 1.1e-117 3.4.17.14, 3.5.1.28 NU amidase activity
BBKJAIEB_00466 6.9e-147 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
BBKJAIEB_00467 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
BBKJAIEB_00468 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BBKJAIEB_00469 1.7e-221 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BBKJAIEB_00470 1.2e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
BBKJAIEB_00471 1.1e-49 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
BBKJAIEB_00472 1.8e-133 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
BBKJAIEB_00473 2.2e-137 yxkH G deacetylase
BBKJAIEB_00474 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
BBKJAIEB_00475 3.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BBKJAIEB_00476 3e-151 rarD S Transporter
BBKJAIEB_00477 3.7e-15 T peptidase
BBKJAIEB_00478 8.9e-14 coiA 3.6.4.12 S Competence protein
BBKJAIEB_00479 8e-51 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BBKJAIEB_00480 2e-45 S FMN binding
BBKJAIEB_00481 6.5e-53 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBKJAIEB_00482 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
BBKJAIEB_00483 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBKJAIEB_00484 2.1e-123 atpB C it plays a direct role in the translocation of protons across the membrane
BBKJAIEB_00485 3.3e-78 atpF C ATP synthase F(0) sector subunit b
BBKJAIEB_00486 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBKJAIEB_00487 9.3e-278 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BBKJAIEB_00488 5.6e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BBKJAIEB_00489 1.4e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BBKJAIEB_00490 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
BBKJAIEB_00491 2.8e-230 ftsW D Belongs to the SEDS family
BBKJAIEB_00492 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBKJAIEB_00493 5.2e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BBKJAIEB_00494 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BBKJAIEB_00495 3.2e-161 holB 2.7.7.7 L dna polymerase iii
BBKJAIEB_00496 5.2e-134 yaaT S stage 0 sporulation protein
BBKJAIEB_00497 9.5e-55 yabA L Involved in initiation control of chromosome replication
BBKJAIEB_00498 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BBKJAIEB_00499 5.8e-233 amt P Ammonium Transporter
BBKJAIEB_00500 6.6e-54 glnB K Belongs to the P(II) protein family
BBKJAIEB_00501 3.2e-105 mur1 NU mannosyl-glycoprotein
BBKJAIEB_00502 2.2e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
BBKJAIEB_00503 4.4e-114 nptA P COG1283 Na phosphate symporter
BBKJAIEB_00504 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBKJAIEB_00505 3.1e-53
BBKJAIEB_00506 1.1e-24
BBKJAIEB_00507 4.7e-21
BBKJAIEB_00508 1.8e-62 S membrane
BBKJAIEB_00509 1.4e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
BBKJAIEB_00510 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
BBKJAIEB_00511 3.8e-38 ynzC S UPF0291 protein
BBKJAIEB_00512 9e-251 cycA E permease
BBKJAIEB_00513 4.1e-09 uvrX 2.7.7.7 L impB/mucB/samB family
BBKJAIEB_00514 7.4e-25 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
BBKJAIEB_00515 2.1e-151 pts33BCA G pts system
BBKJAIEB_00516 1.9e-138 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBKJAIEB_00521 1.7e-165 fhuR K transcriptional regulator (lysR family)
BBKJAIEB_00522 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BBKJAIEB_00523 1.9e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
BBKJAIEB_00524 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BBKJAIEB_00525 4.9e-227 pyrP F uracil Permease
BBKJAIEB_00526 2.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
BBKJAIEB_00527 2.3e-209 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
BBKJAIEB_00528 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
BBKJAIEB_00529 9.3e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
BBKJAIEB_00530 1.3e-29 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBKJAIEB_00531 3.6e-35 V efflux transmembrane transporter activity
BBKJAIEB_00532 3.1e-31 V efflux transmembrane transporter activity
BBKJAIEB_00533 2.1e-23 ytrF V efflux transmembrane transporter activity
BBKJAIEB_00534 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BBKJAIEB_00535 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
BBKJAIEB_00536 0.0 2.1.1.72 LV TaqI-like C-terminal specificity domain
BBKJAIEB_00537 8e-113 2.1.1.72 LV TaqI-like C-terminal specificity domain
BBKJAIEB_00539 3.9e-140 L COG2801 Transposase and inactivated derivatives
BBKJAIEB_00540 1.5e-37 L transposase activity
BBKJAIEB_00541 0.0 mdlB V abc transporter atp-binding protein
BBKJAIEB_00542 0.0 lmrA V abc transporter atp-binding protein
BBKJAIEB_00543 1.7e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BBKJAIEB_00544 2.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BBKJAIEB_00545 1.9e-205 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
BBKJAIEB_00546 1.9e-132 rr02 KT response regulator
BBKJAIEB_00547 1.9e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
BBKJAIEB_00548 2.8e-168 V ABC transporter
BBKJAIEB_00549 5.4e-122 sagI S ABC-2 type transporter
BBKJAIEB_00550 6.9e-197 yceA S Belongs to the UPF0176 family
BBKJAIEB_00551 5.4e-33 XK27_00085 K Transcriptional
BBKJAIEB_00552 1.9e-22
BBKJAIEB_00553 2.2e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
BBKJAIEB_00554 1.1e-111 S VIT family
BBKJAIEB_00555 5.7e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BBKJAIEB_00556 1.8e-86 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
BBKJAIEB_00557 3.5e-117 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
BBKJAIEB_00558 6.4e-16 ald 1.4.1.1 E alanine dehydrogenase activity
BBKJAIEB_00559 1e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
BBKJAIEB_00560 1.8e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBKJAIEB_00561 2e-94 GBS0088 J protein conserved in bacteria
BBKJAIEB_00562 5.1e-143 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
BBKJAIEB_00563 4.3e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
BBKJAIEB_00564 4.7e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
BBKJAIEB_00565 4.4e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
BBKJAIEB_00566 5.6e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBKJAIEB_00567 1.3e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
BBKJAIEB_00568 6.4e-17
BBKJAIEB_00569 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBKJAIEB_00571 3.5e-07 U protein secretion
BBKJAIEB_00572 1.4e-71 U protein secretion
BBKJAIEB_00573 5.2e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
BBKJAIEB_00574 6.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
BBKJAIEB_00575 4.9e-21 XK27_13030
BBKJAIEB_00576 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BBKJAIEB_00577 1.7e-148 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
BBKJAIEB_00578 5.2e-164 S Protein of unknown function (DUF3114)
BBKJAIEB_00579 4.6e-22 S Protein of unknown function (DUF3114)
BBKJAIEB_00580 1.9e-116 yqfA K protein, Hemolysin III
BBKJAIEB_00581 7.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
BBKJAIEB_00582 8.5e-218 mvaS 2.3.3.10 I synthase
BBKJAIEB_00583 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BBKJAIEB_00584 9e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBKJAIEB_00585 9.7e-22
BBKJAIEB_00586 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BBKJAIEB_00587 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
BBKJAIEB_00588 1.9e-248 mmuP E amino acid
BBKJAIEB_00589 1.2e-174 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
BBKJAIEB_00590 1.4e-29 S Domain of unknown function (DUF1912)
BBKJAIEB_00592 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BBKJAIEB_00593 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BBKJAIEB_00594 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BBKJAIEB_00595 5.3e-200 ilvE 2.6.1.42 E Aminotransferase
BBKJAIEB_00596 4.8e-16 S Protein of unknown function (DUF2969)
BBKJAIEB_00599 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
BBKJAIEB_00602 5.1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
BBKJAIEB_00603 3.9e-31 S Domain of Unknown Function with PDB structure (DUF3862)
BBKJAIEB_00604 5.2e-55 M Pfam SNARE associated Golgi protein
BBKJAIEB_00605 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
BBKJAIEB_00606 7.8e-08 S oxidoreductase
BBKJAIEB_00607 9.9e-33 S oxidoreductase
BBKJAIEB_00608 1.9e-66 S oxidoreductase
BBKJAIEB_00609 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
BBKJAIEB_00610 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
BBKJAIEB_00611 0.0 clpE O Belongs to the ClpA ClpB family
BBKJAIEB_00612 1.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBKJAIEB_00613 1.3e-34 ykuJ S protein conserved in bacteria
BBKJAIEB_00614 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
BBKJAIEB_00615 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
BBKJAIEB_00616 1.1e-78 feoA P FeoA domain protein
BBKJAIEB_00617 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
BBKJAIEB_00618 6.6e-08
BBKJAIEB_00619 2.5e-33 yugF I carboxylic ester hydrolase activity
BBKJAIEB_00620 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BBKJAIEB_00621 4.6e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BBKJAIEB_00622 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
BBKJAIEB_00623 9.3e-112 L integrase core domain
BBKJAIEB_00624 8.4e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BBKJAIEB_00625 2.9e-44 licT K transcriptional antiterminator
BBKJAIEB_00626 6.8e-53 licT K transcriptional antiterminator
BBKJAIEB_00627 2.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BBKJAIEB_00628 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
BBKJAIEB_00629 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBKJAIEB_00630 7.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
BBKJAIEB_00631 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BBKJAIEB_00632 5.6e-156 mdtG EGP Major facilitator Superfamily
BBKJAIEB_00633 2e-33 secG U Preprotein translocase subunit SecG
BBKJAIEB_00634 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BBKJAIEB_00635 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
BBKJAIEB_00636 4.1e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BBKJAIEB_00637 4.9e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
BBKJAIEB_00638 2.7e-210 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
BBKJAIEB_00639 4.4e-183 ccpA K Catabolite control protein A
BBKJAIEB_00640 2.8e-28 yyaQ S YjbR
BBKJAIEB_00641 2.8e-43 yyaQ S YjbR
BBKJAIEB_00642 4.1e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
BBKJAIEB_00643 1.3e-78 yueI S Protein of unknown function (DUF1694)
BBKJAIEB_00644 2.8e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BBKJAIEB_00645 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
BBKJAIEB_00646 4.5e-219 ywbD 2.1.1.191 J Methyltransferase
BBKJAIEB_00647 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
BBKJAIEB_00648 4.1e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBKJAIEB_00649 2.5e-200 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BBKJAIEB_00650 9.9e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BBKJAIEB_00651 9.2e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
BBKJAIEB_00652 3.2e-53 yheA S Belongs to the UPF0342 family
BBKJAIEB_00653 4.3e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
BBKJAIEB_00654 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
BBKJAIEB_00655 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BBKJAIEB_00656 2.5e-152 pheA 4.2.1.51 E Prephenate dehydratase
BBKJAIEB_00657 2.4e-246 msrR K Transcriptional regulator
BBKJAIEB_00658 4e-140 ydiA P C4-dicarboxylate transporter malic acid transport protein
BBKJAIEB_00659 4e-184 I acyl-CoA dehydrogenase
BBKJAIEB_00660 5.9e-97 mip S hydroperoxide reductase activity
BBKJAIEB_00661 5e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBKJAIEB_00662 5.8e-104
BBKJAIEB_00663 1.5e-18 K Cro/C1-type HTH DNA-binding domain
BBKJAIEB_00664 3e-45 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
BBKJAIEB_00665 7.3e-28 estA E GDSL-like Lipase/Acylhydrolase
BBKJAIEB_00666 1.7e-11
BBKJAIEB_00667 3.8e-83
BBKJAIEB_00668 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BBKJAIEB_00669 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBKJAIEB_00670 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBKJAIEB_00671 1.7e-185 S CRISPR-associated protein Csn2 subfamily St
BBKJAIEB_00672 1.2e-146 ycgQ S TIGR03943 family
BBKJAIEB_00673 8.7e-154 XK27_03015 S permease
BBKJAIEB_00675 0.0 yhgF K Transcriptional accessory protein
BBKJAIEB_00676 4.7e-84 ydcK S Belongs to the SprT family
BBKJAIEB_00677 2.9e-41 pspC KT PspC domain
BBKJAIEB_00678 1.2e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BBKJAIEB_00679 5.3e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BBKJAIEB_00681 6.5e-62 ytxH S General stress protein
BBKJAIEB_00683 8.9e-178 yegQ O Peptidase U32
BBKJAIEB_00684 3.4e-252 yegQ O Peptidase U32
BBKJAIEB_00685 9.3e-87 bioY S biotin synthase
BBKJAIEB_00687 1.1e-33 XK27_12190 S protein conserved in bacteria
BBKJAIEB_00688 2.7e-236 mntH P H( )-stimulated, divalent metal cation uptake system
BBKJAIEB_00689 2.8e-11
BBKJAIEB_00690 3.1e-68 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
BBKJAIEB_00691 0.0 L helicase
BBKJAIEB_00692 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
BBKJAIEB_00693 2e-21 M LysM domain
BBKJAIEB_00694 6e-125 M LysM domain
BBKJAIEB_00695 3.8e-15
BBKJAIEB_00696 2.3e-175 S hydrolase
BBKJAIEB_00697 5.1e-116 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
BBKJAIEB_00698 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBKJAIEB_00699 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
BBKJAIEB_00700 2.7e-27 P Hemerythrin HHE cation binding domain protein
BBKJAIEB_00701 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBKJAIEB_00702 1.6e-08 MA20_36090 S Protein of unknown function (DUF2974)
BBKJAIEB_00703 1.1e-33 MA20_36090 S Protein of unknown function (DUF2974)
BBKJAIEB_00704 2.7e-39 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BBKJAIEB_00705 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
BBKJAIEB_00706 9.7e-22
BBKJAIEB_00707 2.6e-121 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
BBKJAIEB_00708 4.8e-105
BBKJAIEB_00709 7.5e-135 S Protein conserved in bacteria
BBKJAIEB_00710 3.4e-302 hsdM 2.1.1.72 V type I restriction-modification system
BBKJAIEB_00711 2.9e-16 S double-stranded DNA endodeoxyribonuclease activity
BBKJAIEB_00712 3.4e-175 spd F DNA RNA non-specific endonuclease
BBKJAIEB_00713 1.1e-90 lemA S LemA family
BBKJAIEB_00714 1.8e-135 htpX O Belongs to the peptidase M48B family
BBKJAIEB_00715 4.2e-75 S Psort location CytoplasmicMembrane, score
BBKJAIEB_00716 6.2e-56 S Domain of unknown function (DUF4430)
BBKJAIEB_00717 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BBKJAIEB_00718 3.2e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
BBKJAIEB_00719 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
BBKJAIEB_00720 2.5e-197 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
BBKJAIEB_00721 3e-116 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
BBKJAIEB_00722 1.6e-91 dps P Belongs to the Dps family
BBKJAIEB_00723 4e-80 perR P Belongs to the Fur family
BBKJAIEB_00724 8.4e-28 yqgQ S protein conserved in bacteria
BBKJAIEB_00725 2.9e-179 glk 2.7.1.2 G Glucokinase
BBKJAIEB_00726 0.0 typA T GTP-binding protein TypA
BBKJAIEB_00728 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBKJAIEB_00729 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBKJAIEB_00730 6.9e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
BBKJAIEB_00731 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
BBKJAIEB_00732 2.7e-236 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBKJAIEB_00733 5.1e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBKJAIEB_00734 1.2e-95 sepF D cell septum assembly
BBKJAIEB_00735 2e-34 yggT D integral membrane protein
BBKJAIEB_00736 4.7e-143 ylmH T S4 RNA-binding domain
BBKJAIEB_00737 2.5e-134 divIVA D Cell division protein DivIVA
BBKJAIEB_00738 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BBKJAIEB_00739 8e-48 L Transposase
BBKJAIEB_00740 1.3e-10
BBKJAIEB_00741 8.3e-154 mntH P Mn2 and Fe2 transporters of the NRAMP family
BBKJAIEB_00742 2.3e-63 mntH P Mn2 and Fe2 transporters of the NRAMP family
BBKJAIEB_00743 2e-45 rpmE2 J 50S ribosomal protein L31
BBKJAIEB_00744 1.2e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
BBKJAIEB_00745 7.6e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
BBKJAIEB_00746 8.9e-155 gst O Glutathione S-transferase
BBKJAIEB_00747 1.5e-186 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BBKJAIEB_00748 3.5e-111 tdk 2.7.1.21 F thymidine kinase
BBKJAIEB_00749 1.8e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BBKJAIEB_00750 4.7e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BBKJAIEB_00751 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BBKJAIEB_00752 9e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BBKJAIEB_00753 6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
BBKJAIEB_00754 2e-106 pvaA M lytic transglycosylase activity
BBKJAIEB_00755 0.0 yfiB1 V abc transporter atp-binding protein
BBKJAIEB_00756 0.0 XK27_10035 V abc transporter atp-binding protein
BBKJAIEB_00757 1.6e-09 S D-Ala-teichoic acid biosynthesis protein
BBKJAIEB_00758 4.6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BBKJAIEB_00759 1.7e-237 dltB M Membrane protein involved in D-alanine export
BBKJAIEB_00760 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BBKJAIEB_00761 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BBKJAIEB_00762 4.2e-53 L transposition
BBKJAIEB_00763 7.9e-79 L transposase activity
BBKJAIEB_00764 0.0 3.6.3.8 P cation transport ATPase
BBKJAIEB_00765 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
BBKJAIEB_00772 2.1e-296 hsdM 2.1.1.72 V HsdM N-terminal domain
BBKJAIEB_00773 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
BBKJAIEB_00775 3.1e-122 4.1.1.22 H Histidine carboxylase PI chain
BBKJAIEB_00776 1.1e-169 aaxC E Arginine ornithine antiporter
BBKJAIEB_00778 8.3e-22 L RePlication protein
BBKJAIEB_00779 6.5e-25 L Replication protein
BBKJAIEB_00781 4.6e-13
BBKJAIEB_00783 1.1e-283 S DNA primase
BBKJAIEB_00784 3.5e-118 KL Phage plasmid primase P4 family
BBKJAIEB_00785 1.3e-20
BBKJAIEB_00786 6.5e-14
BBKJAIEB_00789 8e-20 K TRANSCRIPTIONal
BBKJAIEB_00790 7.6e-15 K Cro/C1-type HTH DNA-binding domain
BBKJAIEB_00791 4e-212 sip L Belongs to the 'phage' integrase family
BBKJAIEB_00792 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
BBKJAIEB_00793 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BBKJAIEB_00794 3.4e-140 metF 1.5.1.20 C reductase
BBKJAIEB_00795 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
BBKJAIEB_00796 1.1e-93 panT S ECF transporter, substrate-specific component
BBKJAIEB_00797 4.8e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBKJAIEB_00798 8.1e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
BBKJAIEB_00799 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
BBKJAIEB_00800 8.8e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BBKJAIEB_00801 1.6e-40 T PhoQ Sensor
BBKJAIEB_00802 3.2e-42 T PhoQ Sensor
BBKJAIEB_00803 4.3e-124 T PhoQ Sensor
BBKJAIEB_00804 2.1e-30 rpsT J rRNA binding
BBKJAIEB_00805 3.2e-172 coaA 2.7.1.33 F Pantothenic acid kinase
BBKJAIEB_00806 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
BBKJAIEB_00807 1.3e-24 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
BBKJAIEB_00808 1.1e-22 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
BBKJAIEB_00809 1.7e-100 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
BBKJAIEB_00810 3.2e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBKJAIEB_00811 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBKJAIEB_00812 2.9e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
BBKJAIEB_00813 6.8e-190 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
BBKJAIEB_00814 1.1e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
BBKJAIEB_00815 3.4e-189 yufP S Belongs to the binding-protein-dependent transport system permease family
BBKJAIEB_00816 1.4e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
BBKJAIEB_00817 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
BBKJAIEB_00818 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
BBKJAIEB_00819 6.8e-81 ypmB S Protein conserved in bacteria
BBKJAIEB_00820 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
BBKJAIEB_00821 6.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
BBKJAIEB_00822 1.5e-07
BBKJAIEB_00823 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
BBKJAIEB_00824 7.5e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BBKJAIEB_00825 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
BBKJAIEB_00826 7.2e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
BBKJAIEB_00827 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
BBKJAIEB_00828 7.3e-20 D nuclear chromosome segregation
BBKJAIEB_00829 7e-136 yejC S cyclic nucleotide-binding protein
BBKJAIEB_00830 4.5e-163 rapZ S Displays ATPase and GTPase activities
BBKJAIEB_00831 1.4e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
BBKJAIEB_00832 8.7e-162 whiA K May be required for sporulation
BBKJAIEB_00833 9.8e-106 pepD E Dipeptidase
BBKJAIEB_00834 6.6e-45 pepD E Dipeptidase
BBKJAIEB_00835 5.4e-32 cspD K Cold shock protein domain
BBKJAIEB_00836 2.7e-42 K Cold-Shock Protein
BBKJAIEB_00837 3.3e-184 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
BBKJAIEB_00839 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
BBKJAIEB_00840 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
BBKJAIEB_00841 3.3e-98 cysE 2.3.1.30 E serine acetyltransferase
BBKJAIEB_00842 6.3e-54 L Transposase
BBKJAIEB_00843 3.3e-86 L Transposase
BBKJAIEB_00844 1.4e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
BBKJAIEB_00845 1.8e-113 hsdM 2.1.1.72 V type I restriction-modification system
BBKJAIEB_00846 2e-16 glcU U Glucose uptake
BBKJAIEB_00847 1.8e-128 glcU U Glucose uptake
BBKJAIEB_00848 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
BBKJAIEB_00849 1.5e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
BBKJAIEB_00850 3.7e-88 XK27_10720 D peptidase activity
BBKJAIEB_00851 2.1e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
BBKJAIEB_00852 5.8e-09
BBKJAIEB_00853 1e-171 yeiH S Membrane
BBKJAIEB_00854 2.9e-115 mur1 NU muramidase
BBKJAIEB_00855 4.2e-20 L transposase activity
BBKJAIEB_00856 3.5e-72 L transposition
BBKJAIEB_00857 2.2e-165 cpsY K Transcriptional regulator
BBKJAIEB_00858 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
BBKJAIEB_00859 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
BBKJAIEB_00860 2e-104 artQ P ABC transporter (Permease
BBKJAIEB_00861 3.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
BBKJAIEB_00862 7.1e-158 aatB ET ABC transporter substrate-binding protein
BBKJAIEB_00863 1.4e-139 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBKJAIEB_00864 2.1e-07
BBKJAIEB_00865 2.7e-58 adhP 1.1.1.1 C alcohol dehydrogenase
BBKJAIEB_00866 1.6e-109 adhP 1.1.1.1 C alcohol dehydrogenase
BBKJAIEB_00868 1.1e-48 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
BBKJAIEB_00869 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
BBKJAIEB_00870 1.6e-126 gntR1 K transcriptional
BBKJAIEB_00871 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BBKJAIEB_00872 4.8e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBKJAIEB_00873 2.4e-87 niaX
BBKJAIEB_00874 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
BBKJAIEB_00875 2.8e-128 K DNA-binding helix-turn-helix protein
BBKJAIEB_00876 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BBKJAIEB_00877 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBKJAIEB_00878 1.8e-167 GK ROK family
BBKJAIEB_00879 3.5e-157 dprA LU DNA protecting protein DprA
BBKJAIEB_00880 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBKJAIEB_00881 1.7e-151 S TraX protein
BBKJAIEB_00882 2.1e-120 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BBKJAIEB_00883 8.7e-254 T PhoQ Sensor
BBKJAIEB_00884 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BBKJAIEB_00885 1.1e-152 XK27_05470 E Methionine synthase
BBKJAIEB_00886 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
BBKJAIEB_00887 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBKJAIEB_00888 1.3e-49 IQ Acetoin reductase
BBKJAIEB_00889 9.1e-46 IQ Acetoin reductase
BBKJAIEB_00891 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BBKJAIEB_00893 1.7e-73 dinF V Mate efflux family protein
BBKJAIEB_00894 8.2e-41 dinF V Mate efflux family protein
BBKJAIEB_00895 6e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
BBKJAIEB_00897 2e-113 S TraX protein
BBKJAIEB_00898 7.2e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
BBKJAIEB_00899 1.1e-127 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
BBKJAIEB_00900 7.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
BBKJAIEB_00901 7.6e-183 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBKJAIEB_00902 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBKJAIEB_00903 1.4e-116 cas6 S Pfam:DUF2276
BBKJAIEB_00904 0.0 csm1 S CRISPR-associated protein Csm1 family
BBKJAIEB_00905 3.7e-52 csm2 L Pfam:DUF310
BBKJAIEB_00906 1.6e-117 csm3 L RAMP superfamily
BBKJAIEB_00907 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
BBKJAIEB_00908 1.9e-203 csm5 L CRISPR-associated RAMP protein, Csm5 family
BBKJAIEB_00909 1e-14 csm6 S Psort location Cytoplasmic, score
BBKJAIEB_00910 9.8e-73 csm6 S Psort location Cytoplasmic, score
BBKJAIEB_00911 2e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
BBKJAIEB_00912 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BBKJAIEB_00914 8.1e-48 nylA 3.5.1.4 J Belongs to the amidase family
BBKJAIEB_00915 2.3e-265 dtpT U POT family
BBKJAIEB_00916 3.1e-56 nylA 3.5.1.4 J Belongs to the amidase family
BBKJAIEB_00917 1.7e-31 nylA 3.5.1.4 J Belongs to the amidase family
BBKJAIEB_00918 2.3e-97 yckB ET Belongs to the bacterial solute-binding protein 3 family
BBKJAIEB_00919 7.9e-12 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
BBKJAIEB_00920 9.2e-22 yecS P amino acid transport
BBKJAIEB_00922 3.5e-230 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
BBKJAIEB_00923 1.4e-59 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
BBKJAIEB_00924 9.8e-106 yfiF3 K sequence-specific DNA binding
BBKJAIEB_00925 1e-22 bglC K Transcriptional regulator
BBKJAIEB_00926 7.8e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBKJAIEB_00927 4.5e-239 agcS E (Alanine) symporter
BBKJAIEB_00928 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
BBKJAIEB_00929 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
BBKJAIEB_00930 9.3e-62 S haloacid dehalogenase-like hydrolase
BBKJAIEB_00931 5.5e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BBKJAIEB_00932 3.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
BBKJAIEB_00933 3.6e-217 XK27_04775 S hemerythrin HHE cation binding domain
BBKJAIEB_00934 8.4e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BBKJAIEB_00935 4.9e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
BBKJAIEB_00936 5.5e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BBKJAIEB_00937 2.3e-44 yktA S Belongs to the UPF0223 family
BBKJAIEB_00938 6.5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
BBKJAIEB_00939 1.5e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
BBKJAIEB_00940 3.3e-158 pstS P phosphate
BBKJAIEB_00941 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
BBKJAIEB_00942 1.2e-155 pstA P phosphate transport system permease
BBKJAIEB_00943 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BBKJAIEB_00944 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BBKJAIEB_00945 2.7e-112 phoU P Plays a role in the regulation of phosphate uptake
BBKJAIEB_00946 0.0 pepN 3.4.11.2 E aminopeptidase
BBKJAIEB_00947 2.7e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
BBKJAIEB_00949 2.9e-187 lplA 6.3.1.20 H Lipoate-protein ligase
BBKJAIEB_00950 5.7e-17
BBKJAIEB_00951 3.2e-08
BBKJAIEB_00952 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
BBKJAIEB_00953 5.4e-46 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
BBKJAIEB_00954 1.6e-243 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
BBKJAIEB_00955 2.1e-177 malR K Transcriptional regulator
BBKJAIEB_00956 2e-19 malX G ABC transporter
BBKJAIEB_00957 4.5e-17 malX G maltose binding
BBKJAIEB_00958 8.5e-50 malX G maltose binding
BBKJAIEB_00959 2.4e-111 malF P ABC transporter (Permease
BBKJAIEB_00960 4.6e-25 tatA U protein secretion
BBKJAIEB_00961 1.3e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBKJAIEB_00962 3e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
BBKJAIEB_00963 1.5e-233 ycdB P peroxidase
BBKJAIEB_00964 2.1e-152 ycdO P periplasmic lipoprotein involved in iron transport
BBKJAIEB_00965 9.5e-119 fatB P ABC-type enterochelin transport system, periplasmic component
BBKJAIEB_00966 6e-50 fatB P ABC-type enterochelin transport system, periplasmic component
BBKJAIEB_00967 9.8e-135 yclP 3.6.3.34 P abc transporter atp-binding protein
BBKJAIEB_00968 1.9e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBKJAIEB_00969 2.6e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBKJAIEB_00970 6e-136 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBKJAIEB_00971 2e-61 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBKJAIEB_00972 4.6e-206 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
BBKJAIEB_00973 4.9e-74 3.5.1.28 M GBS Bsp-like repeat
BBKJAIEB_00974 1.3e-98 3.5.1.28 NU amidase activity
BBKJAIEB_00975 1.7e-177 3.5.1.28 NU amidase activity
BBKJAIEB_00976 2.3e-21 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
BBKJAIEB_00977 8.5e-293 lpdA 1.8.1.4 C Dehydrogenase
BBKJAIEB_00978 8.4e-171 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
BBKJAIEB_00979 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
BBKJAIEB_00980 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
BBKJAIEB_00981 7.8e-38 P membrane protein (DUF2207)
BBKJAIEB_00982 1.3e-90 S the current gene model (or a revised gene model) may contain a frame shift
BBKJAIEB_00983 7e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BBKJAIEB_00984 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BBKJAIEB_00985 3.3e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBKJAIEB_00986 3.8e-17 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
BBKJAIEB_00987 5.8e-17 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
BBKJAIEB_00988 7.9e-77 3.4.16.4 M Belongs to the peptidase S11 family
BBKJAIEB_00989 1.9e-158 rssA S Phospholipase, patatin family
BBKJAIEB_00990 1.1e-104 estA E Lysophospholipase L1 and related esterases
BBKJAIEB_00991 3.7e-293 S unusual protein kinase
BBKJAIEB_00992 4.9e-39 S granule-associated protein
BBKJAIEB_00993 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BBKJAIEB_00994 1.8e-137 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BBKJAIEB_00995 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BBKJAIEB_00996 1.3e-199 S hmm pf01594
BBKJAIEB_00997 2.8e-88 G Belongs to the phosphoglycerate mutase family
BBKJAIEB_00998 5.3e-59 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
BBKJAIEB_00999 2.1e-14 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
BBKJAIEB_01000 4.9e-94 V VanZ like family
BBKJAIEB_01001 7.7e-103 L Transposase
BBKJAIEB_01002 3.6e-97 2.7.8.12 GT2 S Glycosyltransferase like family 2
BBKJAIEB_01003 6.9e-40 L Integrase core domain
BBKJAIEB_01004 1.6e-82 L Integrase core domain
BBKJAIEB_01005 1e-15 L Transposase
BBKJAIEB_01006 2.7e-62 tnp L DDE domain
BBKJAIEB_01007 7.6e-24 rgpAc GT4 M group 1 family protein
BBKJAIEB_01008 5.5e-253 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
BBKJAIEB_01009 1.6e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
BBKJAIEB_01010 1.8e-106 cps4C M biosynthesis protein
BBKJAIEB_01011 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
BBKJAIEB_01012 4.5e-253 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
BBKJAIEB_01013 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
BBKJAIEB_01014 9.6e-24 yfeJ 6.3.5.2 F glutamine amidotransferase
BBKJAIEB_01015 1.5e-106 yfeJ 6.3.5.2 F glutamine amidotransferase
BBKJAIEB_01016 2.3e-55 clcA_2 P chloride
BBKJAIEB_01017 2.6e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BBKJAIEB_01018 1.4e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
BBKJAIEB_01019 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BBKJAIEB_01022 7.7e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
BBKJAIEB_01023 3.4e-274 pepV 3.5.1.18 E Dipeptidase
BBKJAIEB_01024 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
BBKJAIEB_01025 6.9e-86 XK27_03610 K Gnat family
BBKJAIEB_01026 4.7e-24 L Transposase
BBKJAIEB_01027 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BBKJAIEB_01028 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
BBKJAIEB_01029 9.8e-89 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBKJAIEB_01030 1.1e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
BBKJAIEB_01031 5e-23 M LysM domain
BBKJAIEB_01032 2.9e-90 ebsA S Family of unknown function (DUF5322)
BBKJAIEB_01033 5.7e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
BBKJAIEB_01034 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BBKJAIEB_01035 4.9e-224 G COG0457 FOG TPR repeat
BBKJAIEB_01036 5e-178 yubA S permease
BBKJAIEB_01037 1.7e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
BBKJAIEB_01038 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
BBKJAIEB_01039 2.5e-124 ftsE D cell division ATP-binding protein FtsE
BBKJAIEB_01040 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBKJAIEB_01041 2.7e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BBKJAIEB_01042 9.2e-183 yjjH S Calcineurin-like phosphoesterase
BBKJAIEB_01043 1.7e-134 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
BBKJAIEB_01044 0.0 pacL 3.6.3.8 P cation transport ATPase
BBKJAIEB_01045 2.6e-67 ywiB S Domain of unknown function (DUF1934)
BBKJAIEB_01046 4.9e-50 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
BBKJAIEB_01047 2e-146 yidA S hydrolases of the HAD superfamily
BBKJAIEB_01048 5.3e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
BBKJAIEB_01049 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
BBKJAIEB_01050 1.3e-233 vicK 2.7.13.3 T Histidine kinase
BBKJAIEB_01051 8.4e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BBKJAIEB_01052 8.7e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
BBKJAIEB_01053 4.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
BBKJAIEB_01054 5e-117 gltJ P ABC transporter (Permease
BBKJAIEB_01055 1.5e-110 tcyB_2 P ABC transporter (permease)
BBKJAIEB_01056 5.5e-129 endA F DNA RNA non-specific endonuclease
BBKJAIEB_01057 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
BBKJAIEB_01058 5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBKJAIEB_01059 2.6e-09 S Protein of unknown function (DUF1146)
BBKJAIEB_01060 7.9e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BBKJAIEB_01061 7.1e-15 G Domain of unknown function (DUF4832)
BBKJAIEB_01062 2.7e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BBKJAIEB_01063 9.6e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
BBKJAIEB_01065 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBKJAIEB_01066 6.1e-88 ytsP 1.8.4.14 T GAF domain-containing protein
BBKJAIEB_01067 1.3e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBKJAIEB_01068 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
BBKJAIEB_01071 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BBKJAIEB_01072 4e-218 XK27_05110 P chloride
BBKJAIEB_01073 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
BBKJAIEB_01074 8.3e-282 clcA P Chloride transporter, ClC family
BBKJAIEB_01075 5.1e-75 fld C Flavodoxin
BBKJAIEB_01077 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
BBKJAIEB_01078 1.6e-151 estA CE1 S Putative esterase
BBKJAIEB_01079 6.6e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBKJAIEB_01080 1.2e-135 XK27_08845 S abc transporter atp-binding protein
BBKJAIEB_01081 2.2e-146 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
BBKJAIEB_01082 1.1e-176 XK27_08835 S ABC transporter substrate binding protein
BBKJAIEB_01083 3.5e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
BBKJAIEB_01084 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
BBKJAIEB_01085 0.0 dnaE 2.7.7.7 L DNA polymerase
BBKJAIEB_01086 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
BBKJAIEB_01087 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBKJAIEB_01088 5.8e-274 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BBKJAIEB_01089 2.5e-43 ysdA L Membrane
BBKJAIEB_01090 3.8e-179 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
BBKJAIEB_01091 4.5e-255 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBKJAIEB_01092 1.3e-11 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BBKJAIEB_01093 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BBKJAIEB_01094 4.3e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
BBKJAIEB_01096 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BBKJAIEB_01097 1.3e-94 ypmS S Protein conserved in bacteria
BBKJAIEB_01098 1.9e-145 ypmR E lipolytic protein G-D-S-L family
BBKJAIEB_01099 1.7e-148 DegV S DegV family
BBKJAIEB_01100 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
BBKJAIEB_01101 1.1e-72 argR K arginine binding
BBKJAIEB_01102 2.5e-158 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
BBKJAIEB_01103 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
BBKJAIEB_01104 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
BBKJAIEB_01105 3.4e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BBKJAIEB_01108 1e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBKJAIEB_01109 8.5e-125 dnaD
BBKJAIEB_01110 1e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BBKJAIEB_01111 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBKJAIEB_01112 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
BBKJAIEB_01113 1.1e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
BBKJAIEB_01114 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BBKJAIEB_01115 1.2e-117 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
BBKJAIEB_01116 4.6e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBKJAIEB_01117 1.4e-238 rodA D Belongs to the SEDS family
BBKJAIEB_01118 1.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
BBKJAIEB_01119 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BBKJAIEB_01120 1.9e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
BBKJAIEB_01121 1.8e-125 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BBKJAIEB_01122 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BBKJAIEB_01123 7.4e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
BBKJAIEB_01124 5.6e-231 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BBKJAIEB_01125 3.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
BBKJAIEB_01126 1.3e-47 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BBKJAIEB_01127 5.7e-118 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BBKJAIEB_01128 1.6e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBKJAIEB_01130 3e-27 L Integrase core domain protein
BBKJAIEB_01131 1.3e-49 L transposition
BBKJAIEB_01132 3.2e-10 L transposase activity
BBKJAIEB_01133 6.1e-37 L Transposase
BBKJAIEB_01134 1.2e-31 XK27_08085
BBKJAIEB_01135 1e-88 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
BBKJAIEB_01136 3.9e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
BBKJAIEB_01137 5.8e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
BBKJAIEB_01138 2e-120 ylfI S tigr01906
BBKJAIEB_01139 1.7e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
BBKJAIEB_01140 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
BBKJAIEB_01141 2.4e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
BBKJAIEB_01144 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
BBKJAIEB_01145 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
BBKJAIEB_01146 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BBKJAIEB_01147 1.3e-207 yurR 1.4.5.1 E oxidoreductase
BBKJAIEB_01148 1.6e-130 zupT P Mediates zinc uptake. May also transport other divalent cations
BBKJAIEB_01149 1.6e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBKJAIEB_01150 6e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
BBKJAIEB_01151 1.3e-70 gtrA S GtrA-like protein
BBKJAIEB_01152 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBKJAIEB_01153 3.9e-168 ybbR S Protein conserved in bacteria
BBKJAIEB_01154 4.7e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BBKJAIEB_01155 6.3e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
BBKJAIEB_01156 8.7e-150 cobQ S glutamine amidotransferase
BBKJAIEB_01157 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BBKJAIEB_01158 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
BBKJAIEB_01159 6.3e-13 MA20_06245 S yiaA/B two helix domain
BBKJAIEB_01161 0.0 uup S abc transporter atp-binding protein
BBKJAIEB_01162 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
BBKJAIEB_01163 1.6e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
BBKJAIEB_01164 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
BBKJAIEB_01165 1.5e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
BBKJAIEB_01166 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBKJAIEB_01167 7.9e-39 ptsH G phosphocarrier protein Hpr
BBKJAIEB_01168 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
BBKJAIEB_01169 1.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
BBKJAIEB_01170 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BBKJAIEB_01171 2.2e-34 nrdH O Glutaredoxin
BBKJAIEB_01172 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBKJAIEB_01173 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBKJAIEB_01175 3.1e-56 L Transposase (IS116 IS110 IS902 family)
BBKJAIEB_01176 1.6e-61 L Transposase (IS116 IS110 IS902 family)
BBKJAIEB_01177 4.9e-163 ypuA S secreted protein
BBKJAIEB_01178 3.6e-54 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
BBKJAIEB_01179 8.7e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
BBKJAIEB_01180 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBKJAIEB_01181 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
BBKJAIEB_01182 2.8e-257 noxE P NADH oxidase
BBKJAIEB_01183 9.5e-294 yfmM S abc transporter atp-binding protein
BBKJAIEB_01184 6e-44 XK27_01265 S ECF-type riboflavin transporter, S component
BBKJAIEB_01185 1.5e-11 XK27_01265 S ECF-type riboflavin transporter, S component
BBKJAIEB_01186 3.9e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
BBKJAIEB_01187 1e-43 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
BBKJAIEB_01188 2e-86 S ECF-type riboflavin transporter, S component
BBKJAIEB_01190 4.2e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BBKJAIEB_01191 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
BBKJAIEB_01194 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BBKJAIEB_01195 9.2e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BBKJAIEB_01196 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BBKJAIEB_01197 0.0 smc D Required for chromosome condensation and partitioning
BBKJAIEB_01198 3.2e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BBKJAIEB_01199 2.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBKJAIEB_01200 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BBKJAIEB_01201 3.1e-92 pat 2.3.1.183 M acetyltransferase
BBKJAIEB_01202 1.9e-13
BBKJAIEB_01203 4.3e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBKJAIEB_01204 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
BBKJAIEB_01205 6.3e-35 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
BBKJAIEB_01206 5.6e-21 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
BBKJAIEB_01207 1.1e-121 sdaAB 4.3.1.17 E L-serine dehydratase
BBKJAIEB_01208 1.8e-148 sdaAA 4.3.1.17 E L-serine dehydratase
BBKJAIEB_01209 5.1e-142 S ABC-2 family transporter protein
BBKJAIEB_01210 4.1e-34 S transport system, permease component
BBKJAIEB_01211 1.5e-43 S transport system, permease component
BBKJAIEB_01212 7.7e-42 S transport system, permease component
BBKJAIEB_01213 1.5e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BBKJAIEB_01214 5.7e-192 desK 2.7.13.3 T Histidine kinase
BBKJAIEB_01215 4.8e-134 yvfS V ABC-2 type transporter
BBKJAIEB_01216 2.6e-155 XK27_09825 V abc transporter atp-binding protein
BBKJAIEB_01219 3.9e-165 yocS S Transporter
BBKJAIEB_01220 1.2e-73 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
BBKJAIEB_01222 7.5e-115 yvfS V Transporter
BBKJAIEB_01223 1.3e-154 XK27_09825 V abc transporter atp-binding protein
BBKJAIEB_01224 1.6e-14 liaI KT membrane
BBKJAIEB_01225 1.3e-29 liaI KT membrane
BBKJAIEB_01226 1.4e-92 XK27_05000 S Fe-S-cluster oxidoreductase
BBKJAIEB_01227 1.2e-251 V ABC transporter (permease)
BBKJAIEB_01228 1.8e-58 V ABC transporter (permease)
BBKJAIEB_01229 9.3e-133 macB2 V ABC transporter, ATP-binding protein
BBKJAIEB_01230 4e-165 T Histidine kinase
BBKJAIEB_01231 7.8e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BBKJAIEB_01232 3.9e-76 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
BBKJAIEB_01234 7.9e-74 pbuX F xanthine permease
BBKJAIEB_01235 4.6e-48 pbuX F Permease family
BBKJAIEB_01236 1.3e-35 pbuX F xanthine permease
BBKJAIEB_01237 7.6e-247 norM V Multidrug efflux pump
BBKJAIEB_01238 4.1e-186 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBKJAIEB_01239 2e-78 yxeM ET Belongs to the bacterial solute-binding protein 3 family
BBKJAIEB_01240 2.9e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
BBKJAIEB_01241 7.3e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
BBKJAIEB_01242 4.1e-63 yxeN U ABC transporter, permease protein
BBKJAIEB_01243 5.4e-58 yxeL K Acetyltransferase (GNAT) domain
BBKJAIEB_01244 8.8e-115 yxeQ S MmgE/PrpD family
BBKJAIEB_01245 1.1e-148 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
BBKJAIEB_01246 3e-42 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
BBKJAIEB_01247 1.5e-50 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
BBKJAIEB_01248 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
BBKJAIEB_01249 3e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
BBKJAIEB_01250 2.1e-233 brnQ E Component of the transport system for branched-chain amino acids
BBKJAIEB_01251 5.7e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
BBKJAIEB_01252 2.8e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
BBKJAIEB_01253 9.6e-26 csbD K CsbD-like
BBKJAIEB_01254 1.1e-227 yfnA E amino acid
BBKJAIEB_01255 1.9e-77 S dextransucrase activity
BBKJAIEB_01256 1.7e-106 S dextransucrase activity
BBKJAIEB_01257 8e-138 S dextransucrase activity
BBKJAIEB_01258 2.7e-32 L Integrase core domain protein
BBKJAIEB_01261 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
BBKJAIEB_01262 3e-114 yxeN P ABC transporter, permease protein
BBKJAIEB_01263 6.1e-107 ytmL P ABC transporter (Permease
BBKJAIEB_01264 3.5e-160 ET ABC transporter substrate-binding protein
BBKJAIEB_01265 8.1e-161 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
BBKJAIEB_01266 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
BBKJAIEB_01267 1.9e-40 S Sugar efflux transporter for intercellular exchange
BBKJAIEB_01268 1.1e-24 P FtsX-like permease family
BBKJAIEB_01269 1.1e-36 V abc transporter atp-binding protein
BBKJAIEB_01270 1.7e-67 K WHG domain
BBKJAIEB_01271 5e-148 ydhF S Aldo keto reductase
BBKJAIEB_01273 5.3e-107 XK27_02070 S nitroreductase
BBKJAIEB_01274 5.8e-67 1.13.11.2 S glyoxalase
BBKJAIEB_01275 3.6e-76 ywnA K Transcriptional regulator
BBKJAIEB_01276 1.9e-147 E Alpha/beta hydrolase of unknown function (DUF915)
BBKJAIEB_01277 1.3e-230 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BBKJAIEB_01278 1.3e-111 drgA C Nitroreductase
BBKJAIEB_01279 1.1e-88 yoaK S Protein of unknown function (DUF1275)
BBKJAIEB_01280 1.7e-159 yvgN C reductase
BBKJAIEB_01281 2.2e-96 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BBKJAIEB_01282 1.3e-51 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BBKJAIEB_01283 8.1e-279 XK27_07020 S Belongs to the UPF0371 family
BBKJAIEB_01285 9.6e-37 BP1961 P nitric oxide dioxygenase activity
BBKJAIEB_01286 2.4e-54 K response regulator
BBKJAIEB_01287 6.7e-70 S Signal peptide protein, YSIRK family
BBKJAIEB_01289 8.7e-57
BBKJAIEB_01290 2.4e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBKJAIEB_01291 1.8e-61
BBKJAIEB_01292 2e-11 IQ PFAM AMP-dependent synthetase and ligase
BBKJAIEB_01293 5.8e-109 MA20_06410 E LysE type translocator
BBKJAIEB_01294 2.7e-09
BBKJAIEB_01295 0.0 M family 8
BBKJAIEB_01296 2.2e-23 L Transposase
BBKJAIEB_01297 3.1e-185 cps1C S Polysaccharide biosynthesis protein
BBKJAIEB_01298 5.9e-19
BBKJAIEB_01300 1e-81 L Transposase and inactivated derivatives
BBKJAIEB_01301 9e-44 L COG2963 Transposase and inactivated derivatives
BBKJAIEB_01302 1e-31
BBKJAIEB_01303 0.0 sbcC L ATPase involved in DNA repair
BBKJAIEB_01304 2.6e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
BBKJAIEB_01305 0.0 lacL 3.2.1.23 G -beta-galactosidase
BBKJAIEB_01306 0.0 lacS G transporter
BBKJAIEB_01307 1.7e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
BBKJAIEB_01308 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
BBKJAIEB_01309 1.6e-293 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
BBKJAIEB_01310 5.8e-219 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BBKJAIEB_01311 8.9e-184 galR K Transcriptional regulator
BBKJAIEB_01312 7.1e-09 L Integrase core domain protein
BBKJAIEB_01313 1.2e-25 L transposition
BBKJAIEB_01314 1.3e-182 M translation initiation factor activity
BBKJAIEB_01315 1e-33 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
BBKJAIEB_01316 4.6e-18 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
BBKJAIEB_01317 1.3e-102 V abc transporter atp-binding protein
BBKJAIEB_01318 1e-41 V (ABC) transporter
BBKJAIEB_01319 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
BBKJAIEB_01320 4.6e-73 L Transposase
BBKJAIEB_01321 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
BBKJAIEB_01322 2.7e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
BBKJAIEB_01323 4.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
BBKJAIEB_01324 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BBKJAIEB_01327 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BBKJAIEB_01328 5.8e-175 vraS 2.7.13.3 T Histidine kinase
BBKJAIEB_01329 3.7e-120 yvqF KT membrane
BBKJAIEB_01330 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
BBKJAIEB_01331 2e-132 stp 3.1.3.16 T phosphatase
BBKJAIEB_01332 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBKJAIEB_01333 3.5e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BBKJAIEB_01334 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBKJAIEB_01335 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
BBKJAIEB_01336 3.4e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
BBKJAIEB_01337 2.2e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BBKJAIEB_01338 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
BBKJAIEB_01339 5.3e-147 supH S overlaps another CDS with the same product name
BBKJAIEB_01340 8.6e-63 yvoA_1 K Transcriptional
BBKJAIEB_01341 9.8e-121 skfE V abc transporter atp-binding protein
BBKJAIEB_01342 3.3e-133 V ATPase activity
BBKJAIEB_01343 6.6e-40 oppF P Belongs to the ABC transporter superfamily
BBKJAIEB_01344 2e-46 oppF P Belongs to the ABC transporter superfamily
BBKJAIEB_01345 6.9e-22 tatD L hydrolase, TatD family'
BBKJAIEB_01346 2.8e-216 oxlT P COG0477 Permeases of the major facilitator superfamily
BBKJAIEB_01347 1e-84 L PFAM Integrase catalytic region
BBKJAIEB_01348 5.1e-27 L transposition
BBKJAIEB_01349 2.8e-22 L transposase activity
BBKJAIEB_01350 1.1e-43 L transposase activity
BBKJAIEB_01351 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
BBKJAIEB_01352 4.9e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
BBKJAIEB_01353 4e-153 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BBKJAIEB_01354 4.2e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
BBKJAIEB_01355 1.5e-103 yjbK S Adenylate cyclase
BBKJAIEB_01356 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBKJAIEB_01357 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
BBKJAIEB_01358 3.1e-59 XK27_04120 S Putative amino acid metabolism
BBKJAIEB_01359 1.2e-115 radC E Belongs to the UPF0758 family
BBKJAIEB_01360 0.0 rgpF M Rhamnan synthesis protein F
BBKJAIEB_01361 3.1e-195 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
BBKJAIEB_01362 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
BBKJAIEB_01363 1.4e-142 rgpC GM Transport permease protein
BBKJAIEB_01364 1.4e-178 rgpB GT2 M Glycosyltransferase, group 2 family protein
BBKJAIEB_01365 7.7e-224 rgpA GT4 M Domain of unknown function (DUF1972)
BBKJAIEB_01366 1.7e-141 S Predicted membrane protein (DUF2142)
BBKJAIEB_01367 1.5e-183 tagF 2.7.8.12 M Glycosyl transferase, family 2
BBKJAIEB_01368 5.8e-220 amrA S polysaccharide biosynthetic process
BBKJAIEB_01369 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
BBKJAIEB_01370 2.2e-125 ycbB S Glycosyl transferase family 2
BBKJAIEB_01371 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
BBKJAIEB_01372 5.3e-122
BBKJAIEB_01373 5.3e-25
BBKJAIEB_01374 6.5e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
BBKJAIEB_01375 7.6e-55 yitW K metal-sulfur cluster biosynthetic enzyme
BBKJAIEB_01376 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BBKJAIEB_01377 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BBKJAIEB_01378 2.5e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
BBKJAIEB_01379 3.6e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
BBKJAIEB_01380 4.2e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
BBKJAIEB_01381 5.2e-201 arcT 2.6.1.1 E Aminotransferase
BBKJAIEB_01382 4.2e-136 ET ABC transporter
BBKJAIEB_01383 1.1e-142 ET Belongs to the bacterial solute-binding protein 3 family
BBKJAIEB_01384 2.9e-84 mutT 3.6.1.55 F Nudix family
BBKJAIEB_01385 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
BBKJAIEB_01387 1.6e-55 V CAAX protease self-immunity
BBKJAIEB_01388 7.6e-32 S CAAX amino terminal protease family protein
BBKJAIEB_01389 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
BBKJAIEB_01390 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
BBKJAIEB_01391 1.1e-16 XK27_00735
BBKJAIEB_01392 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBKJAIEB_01394 2.3e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
BBKJAIEB_01397 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
BBKJAIEB_01398 3e-37 ycaO O OsmC-like protein
BBKJAIEB_01400 5e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
BBKJAIEB_01401 6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
BBKJAIEB_01402 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBKJAIEB_01403 3.4e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBKJAIEB_01404 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BBKJAIEB_01405 7.7e-198 V (ABC) transporter
BBKJAIEB_01406 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
BBKJAIEB_01407 8e-277 S Protein of unknown function (DUF3114)
BBKJAIEB_01409 7.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
BBKJAIEB_01410 2.1e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BBKJAIEB_01411 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBKJAIEB_01412 1.3e-108 3.1.3.18 S IA, variant 1
BBKJAIEB_01413 2.2e-117 lrgB M effector of murein hydrolase
BBKJAIEB_01414 5e-55 lrgA S Effector of murein hydrolase LrgA
BBKJAIEB_01416 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
BBKJAIEB_01417 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
BBKJAIEB_01418 1.2e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBKJAIEB_01419 1.3e-104 wecD M Acetyltransferase (GNAT) domain
BBKJAIEB_01420 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BBKJAIEB_01421 5.5e-29 GK ROK family
BBKJAIEB_01422 5e-53 GK ROK family
BBKJAIEB_01423 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
BBKJAIEB_01424 1.4e-49 XK27_08050 O HflC and HflK could regulate a protease
BBKJAIEB_01425 1.7e-36 XK27_08050 O HflC and HflK could regulate a protease
BBKJAIEB_01426 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
BBKJAIEB_01427 9.8e-205 potD P spermidine putrescine ABC transporter
BBKJAIEB_01428 1.1e-133 potC P ABC-type spermidine putrescine transport system, permease component II
BBKJAIEB_01429 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
BBKJAIEB_01430 4.7e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
BBKJAIEB_01431 3.9e-170 murB 1.3.1.98 M cell wall formation
BBKJAIEB_01432 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBKJAIEB_01433 7.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BBKJAIEB_01434 1.3e-295 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
BBKJAIEB_01435 2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BBKJAIEB_01436 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
BBKJAIEB_01437 0.0 ydaO E amino acid
BBKJAIEB_01438 7.2e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
BBKJAIEB_01439 4.1e-37 ylqC L Belongs to the UPF0109 family
BBKJAIEB_01440 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
BBKJAIEB_01441 6.9e-172 tehB 2.1.1.265 Q Methyltransferase
BBKJAIEB_01442 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
BBKJAIEB_01443 2.1e-74 S QueT transporter
BBKJAIEB_01444 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
BBKJAIEB_01445 3.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
BBKJAIEB_01446 1.6e-185 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
BBKJAIEB_01447 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBKJAIEB_01448 1.4e-84 ccl S cog cog4708
BBKJAIEB_01449 2.2e-160 rbn E Belongs to the UPF0761 family
BBKJAIEB_01450 3.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
BBKJAIEB_01451 6.6e-232 ytoI K transcriptional regulator containing CBS domains
BBKJAIEB_01452 1.8e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
BBKJAIEB_01453 1.3e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBKJAIEB_01454 1.1e-300 comEC S Competence protein ComEC
BBKJAIEB_01455 1.6e-98 comEC S Competence protein ComEC
BBKJAIEB_01456 1.2e-97 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
BBKJAIEB_01457 1.3e-142 plsC 2.3.1.51 I Acyltransferase
BBKJAIEB_01458 6.4e-80 nodB3 G polysaccharide deacetylase
BBKJAIEB_01459 8e-42 nodB3 G polysaccharide deacetylase
BBKJAIEB_01460 2.9e-27 L Transposase
BBKJAIEB_01461 3.7e-137 yabB 2.1.1.223 L Methyltransferase
BBKJAIEB_01462 3e-41 yazA L endonuclease containing a URI domain
BBKJAIEB_01463 1.4e-247 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
BBKJAIEB_01464 2.3e-154 corA P CorA-like protein
BBKJAIEB_01465 2.5e-62 yjqA S Bacterial PH domain
BBKJAIEB_01466 2.3e-99 thiT S Thiamine transporter
BBKJAIEB_01467 9.5e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
BBKJAIEB_01468 9.7e-119 yjbB G Permeases of the major facilitator superfamily
BBKJAIEB_01469 1.5e-47 yjbB G Permeases of the major facilitator superfamily
BBKJAIEB_01470 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BBKJAIEB_01471 1.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
BBKJAIEB_01472 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
BBKJAIEB_01476 1.5e-155 cjaA ET ABC transporter substrate-binding protein
BBKJAIEB_01477 4.4e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
BBKJAIEB_01478 1.5e-99 papP P ABC transporter (Permease
BBKJAIEB_01479 3.2e-192 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
BBKJAIEB_01480 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
BBKJAIEB_01481 0.0 copA 3.6.3.54 P P-type ATPase
BBKJAIEB_01482 1.8e-72 copY K negative regulation of transcription, DNA-templated
BBKJAIEB_01483 2.3e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
BBKJAIEB_01484 4.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BBKJAIEB_01485 5.5e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
BBKJAIEB_01486 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
BBKJAIEB_01487 2.5e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBKJAIEB_01488 4.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
BBKJAIEB_01489 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BBKJAIEB_01490 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
BBKJAIEB_01491 3.2e-56
BBKJAIEB_01492 0.0 ctpE P E1-E2 ATPase
BBKJAIEB_01493 6.1e-27
BBKJAIEB_01494 2.1e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BBKJAIEB_01495 5.1e-47 L transposase activity
BBKJAIEB_01496 1.3e-94 K transcriptional regulator, MerR family
BBKJAIEB_01497 6.2e-12 K transcriptional regulator, MerR family
BBKJAIEB_01498 2.3e-102 dnaQ 2.7.7.7 L DNA polymerase III
BBKJAIEB_01499 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
BBKJAIEB_01500 1.2e-57 XK27_02560 S cog cog2151
BBKJAIEB_01501 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
BBKJAIEB_01502 7.7e-227 ytfP S Flavoprotein
BBKJAIEB_01504 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
BBKJAIEB_01505 3.5e-151 ytmP 2.7.1.89 M Phosphotransferase
BBKJAIEB_01506 3.6e-180 ecsB U ABC transporter
BBKJAIEB_01507 1.1e-130 ecsA V abc transporter atp-binding protein
BBKJAIEB_01508 2.5e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
BBKJAIEB_01510 1.2e-106
BBKJAIEB_01512 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
BBKJAIEB_01513 1.3e-204 ylbM S Belongs to the UPF0348 family
BBKJAIEB_01514 3.5e-140 yqeM Q Methyltransferase domain protein
BBKJAIEB_01515 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
BBKJAIEB_01516 1.5e-106 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
BBKJAIEB_01517 9.2e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBKJAIEB_01518 3.5e-49 yhbY J RNA-binding protein
BBKJAIEB_01519 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
BBKJAIEB_01520 1.8e-98 yqeG S hydrolase of the HAD superfamily
BBKJAIEB_01521 1.5e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
BBKJAIEB_01522 1.4e-65
BBKJAIEB_01523 5.1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBKJAIEB_01524 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
BBKJAIEB_01525 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBKJAIEB_01526 2.2e-254 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
BBKJAIEB_01527 5.1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBKJAIEB_01528 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
BBKJAIEB_01529 3.4e-100 pncA Q isochorismatase
BBKJAIEB_01530 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BBKJAIEB_01531 8.5e-234 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
BBKJAIEB_01532 4.4e-74 XK27_03180 T universal stress protein
BBKJAIEB_01534 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBKJAIEB_01535 9.9e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
BBKJAIEB_01536 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
BBKJAIEB_01537 0.0 yjcE P NhaP-type Na H and K H antiporters
BBKJAIEB_01539 2.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
BBKJAIEB_01540 8.4e-184 yhcC S radical SAM protein
BBKJAIEB_01541 3.2e-195 ylbL T Belongs to the peptidase S16 family
BBKJAIEB_01542 1e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBKJAIEB_01543 1.1e-92 rsmD 2.1.1.171 L Methyltransferase
BBKJAIEB_01544 9.4e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
BBKJAIEB_01545 1.9e-09 S Protein of unknown function (DUF4059)
BBKJAIEB_01546 8.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
BBKJAIEB_01547 2e-161 yxeN P ABC transporter (Permease
BBKJAIEB_01548 4.8e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
BBKJAIEB_01550 6.8e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBKJAIEB_01551 0.0 pflB 2.3.1.54 C formate acetyltransferase'
BBKJAIEB_01552 4.7e-64 cah 4.2.1.1 P carbonic anhydrase
BBKJAIEB_01553 1.3e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BBKJAIEB_01554 2.5e-46 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
BBKJAIEB_01555 4.9e-31 D nuclear chromosome segregation
BBKJAIEB_01556 2.7e-32 L DNA integration
BBKJAIEB_01557 3.2e-124 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
BBKJAIEB_01558 1e-123 ybbM S transport system, permease component
BBKJAIEB_01559 9.4e-118 ybbL S abc transporter atp-binding protein
BBKJAIEB_01560 2.9e-29
BBKJAIEB_01561 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
BBKJAIEB_01562 2.1e-48 cppA E CppA N-terminal
BBKJAIEB_01563 2.4e-75 cppA E CppA N-terminal
BBKJAIEB_01564 9.1e-30 V CAAX protease self-immunity
BBKJAIEB_01565 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
BBKJAIEB_01566 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
BBKJAIEB_01569 3e-47 spiA K sequence-specific DNA binding
BBKJAIEB_01570 9.5e-140 blpT
BBKJAIEB_01575 5.1e-17 S Bacteriocin class II with double-glycine leader peptide
BBKJAIEB_01576 1.5e-71 agrA KT phosphorelay signal transduction system
BBKJAIEB_01577 6e-45 agrA KT phosphorelay signal transduction system
BBKJAIEB_01578 3.8e-238 blpH 2.7.13.3 T protein histidine kinase activity
BBKJAIEB_01580 4e-235 mesE M Transport protein ComB
BBKJAIEB_01581 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BBKJAIEB_01582 0.0 mdlB V abc transporter atp-binding protein
BBKJAIEB_01583 0.0 mdlA V abc transporter atp-binding protein
BBKJAIEB_01585 5e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
BBKJAIEB_01586 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BBKJAIEB_01587 2.4e-66 yutD J protein conserved in bacteria
BBKJAIEB_01588 4.8e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
BBKJAIEB_01590 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
BBKJAIEB_01591 5.9e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBKJAIEB_01592 0.0 ftsI 3.4.16.4 M penicillin-binding protein
BBKJAIEB_01593 4.3e-47 ftsL D cell division protein FtsL
BBKJAIEB_01594 1.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BBKJAIEB_01595 9.9e-86
BBKJAIEB_01596 3.4e-58
BBKJAIEB_01597 2.4e-20 yhaI J Protein of unknown function (DUF805)
BBKJAIEB_01599 6.9e-210 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BBKJAIEB_01600 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BBKJAIEB_01601 9.2e-284 XK27_00765
BBKJAIEB_01602 2.1e-129 ecsA_2 V abc transporter atp-binding protein
BBKJAIEB_01603 9.3e-122 S Protein of unknown function (DUF554)
BBKJAIEB_01604 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
BBKJAIEB_01605 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BBKJAIEB_01606 2.6e-66 liaI S membrane
BBKJAIEB_01607 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
BBKJAIEB_01608 8.5e-68 KT response to antibiotic
BBKJAIEB_01609 3.5e-17 KT response to antibiotic
BBKJAIEB_01610 1.6e-79 yebC M Membrane
BBKJAIEB_01611 2.9e-18 yebC M Membrane
BBKJAIEB_01612 2.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
BBKJAIEB_01613 3.2e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
BBKJAIEB_01614 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBKJAIEB_01615 2e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBKJAIEB_01616 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
BBKJAIEB_01617 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBKJAIEB_01618 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBKJAIEB_01619 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BBKJAIEB_01621 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
BBKJAIEB_01622 3.1e-26 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
BBKJAIEB_01623 2e-135 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
BBKJAIEB_01624 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
BBKJAIEB_01625 1.2e-290 scrB 3.2.1.26 GH32 G invertase
BBKJAIEB_01626 2.9e-179 scrR K Transcriptional
BBKJAIEB_01627 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBKJAIEB_01628 3.4e-62 yqhY S protein conserved in bacteria
BBKJAIEB_01629 1.6e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BBKJAIEB_01630 1.4e-83 comEB 3.5.4.12 F ComE operon protein 2
BBKJAIEB_01631 8e-191 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
BBKJAIEB_01633 2.3e-43 V 'abc transporter, ATP-binding protein
BBKJAIEB_01636 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBKJAIEB_01637 2e-169 corA P COG0598 Mg2 and Co2 transporters
BBKJAIEB_01638 3.1e-124 XK27_01040 S Pfam PF06570
BBKJAIEB_01640 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BBKJAIEB_01641 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BBKJAIEB_01642 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
BBKJAIEB_01643 1.2e-41 XK27_05745
BBKJAIEB_01644 4.2e-230 mutY L A G-specific adenine glycosylase
BBKJAIEB_01648 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBKJAIEB_01649 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BBKJAIEB_01650 1e-93 cvpA S toxin biosynthetic process
BBKJAIEB_01651 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BBKJAIEB_01652 1.8e-159 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBKJAIEB_01653 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
BBKJAIEB_01654 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BBKJAIEB_01655 8.8e-48 azlD E branched-chain amino acid
BBKJAIEB_01656 5.5e-116 azlC E AzlC protein
BBKJAIEB_01657 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBKJAIEB_01658 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
BBKJAIEB_01659 2.1e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
BBKJAIEB_01660 2.5e-33 ykzG S Belongs to the UPF0356 family
BBKJAIEB_01661 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBKJAIEB_01662 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
BBKJAIEB_01663 1.9e-62 glnR K Transcriptional regulator
BBKJAIEB_01664 1.3e-87 S Fusaric acid resistance protein-like
BBKJAIEB_01665 5.1e-13
BBKJAIEB_01666 1.1e-30
BBKJAIEB_01667 3.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
BBKJAIEB_01668 5.5e-42 L Transposase
BBKJAIEB_01669 4.5e-89 L Transposase and inactivated derivatives
BBKJAIEB_01670 2.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BBKJAIEB_01671 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBKJAIEB_01672 4.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
BBKJAIEB_01673 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BBKJAIEB_01674 1.1e-142 purR 2.4.2.7 F operon repressor
BBKJAIEB_01675 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
BBKJAIEB_01676 6.9e-173 rmuC S RmuC domain protein
BBKJAIEB_01677 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
BBKJAIEB_01678 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
BBKJAIEB_01679 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BBKJAIEB_01681 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
BBKJAIEB_01682 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BBKJAIEB_01683 4.1e-144 tatD L Hydrolase, tatd
BBKJAIEB_01684 1.5e-74 yccU S CoA-binding protein
BBKJAIEB_01685 6.3e-51 trxA O Belongs to the thioredoxin family
BBKJAIEB_01686 6.6e-142 S Macro domain protein
BBKJAIEB_01687 6.3e-11 L thioesterase
BBKJAIEB_01688 2.9e-54 bta 1.8.1.8 CO cell redox homeostasis
BBKJAIEB_01691 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
BBKJAIEB_01692 1.1e-83 L Transposase
BBKJAIEB_01693 1e-13 rpmH J Ribosomal protein L34
BBKJAIEB_01694 3.8e-185 jag S RNA-binding protein
BBKJAIEB_01695 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BBKJAIEB_01696 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
BBKJAIEB_01697 9.2e-264 argH 4.3.2.1 E Argininosuccinate lyase
BBKJAIEB_01698 1.3e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
BBKJAIEB_01699 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBKJAIEB_01700 9.5e-63 amiA E transmembrane transport
BBKJAIEB_01701 4.2e-74 amiA E transmembrane transport
BBKJAIEB_01702 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
BBKJAIEB_01703 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BBKJAIEB_01704 9.2e-51 S Protein of unknown function (DUF3397)
BBKJAIEB_01705 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
BBKJAIEB_01706 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
BBKJAIEB_01707 8.1e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
BBKJAIEB_01708 4.8e-227 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BBKJAIEB_01709 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
BBKJAIEB_01710 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
BBKJAIEB_01711 5.8e-74 XK27_09620 S reductase
BBKJAIEB_01712 8.4e-60 XK27_09615 C reductase
BBKJAIEB_01713 1e-142 XK27_09615 C reductase
BBKJAIEB_01714 2.3e-52 fnt P Formate nitrite transporter
BBKJAIEB_01715 9.6e-49 fnt P Formate nitrite transporter
BBKJAIEB_01716 1.1e-48 XK27_08585 S Psort location CytoplasmicMembrane, score
BBKJAIEB_01717 2.2e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
BBKJAIEB_01718 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
BBKJAIEB_01719 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
BBKJAIEB_01720 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBKJAIEB_01721 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
BBKJAIEB_01722 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
BBKJAIEB_01723 6e-48 S glycolate biosynthetic process
BBKJAIEB_01724 4e-65 S phosphatase activity
BBKJAIEB_01725 2e-157 rrmA 2.1.1.187 Q methyltransferase
BBKJAIEB_01728 4.6e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
BBKJAIEB_01729 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BBKJAIEB_01730 1.9e-36 yeeD O sulfur carrier activity
BBKJAIEB_01731 1e-187 yeeE S Sulphur transport
BBKJAIEB_01732 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BBKJAIEB_01733 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
BBKJAIEB_01734 4.1e-09 S Domain of unknown function (DUF4651)
BBKJAIEB_01735 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
BBKJAIEB_01736 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBKJAIEB_01737 8.7e-111 S CAAX amino terminal protease family protein
BBKJAIEB_01739 1.4e-66 V CAAX protease self-immunity
BBKJAIEB_01740 3.6e-34 V CAAX protease self-immunity
BBKJAIEB_01741 3.4e-26 lanR K sequence-specific DNA binding
BBKJAIEB_01742 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBKJAIEB_01743 5.9e-177 ytxK 2.1.1.72 L DNA methylase
BBKJAIEB_01744 6.8e-13 comGF U Putative Competence protein ComGF
BBKJAIEB_01745 2.9e-70 comGF U Competence protein ComGF
BBKJAIEB_01746 1.4e-15 NU Type II secretory pathway pseudopilin
BBKJAIEB_01747 1.8e-57 cglD NU Competence protein
BBKJAIEB_01748 2.5e-42 comGC U Required for transformation and DNA binding
BBKJAIEB_01749 2.8e-91 cglB NU type II secretion system
BBKJAIEB_01750 5.3e-44 cglB NU type II secretion system
BBKJAIEB_01751 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBKJAIEB_01752 2.5e-67 S cog cog4699
BBKJAIEB_01753 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBKJAIEB_01754 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBKJAIEB_01755 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
BBKJAIEB_01756 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BBKJAIEB_01757 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BBKJAIEB_01758 3.8e-76 ilvN 2.2.1.6 E Acetolactate synthase
BBKJAIEB_01759 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
BBKJAIEB_01760 1.8e-248 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
BBKJAIEB_01761 5.5e-66 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
BBKJAIEB_01762 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
BBKJAIEB_01763 8.9e-57 asp S cog cog1302
BBKJAIEB_01764 7.1e-226 norM V Mate efflux family protein
BBKJAIEB_01765 4.1e-278 thrC 4.2.3.1 E Threonine synthase
BBKJAIEB_01766 7.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BBKJAIEB_01767 3.8e-31 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
BBKJAIEB_01768 1.3e-66 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BBKJAIEB_01769 1.2e-133 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
BBKJAIEB_01770 2.1e-52 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
BBKJAIEB_01771 0.0 pepO 3.4.24.71 O Peptidase family M13
BBKJAIEB_01772 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
BBKJAIEB_01773 1.7e-59 treC 3.2.1.93 GH13 G COG0366 Glycosidases
BBKJAIEB_01774 8.3e-55 treB 2.7.1.201 G PTS System
BBKJAIEB_01775 5.8e-21 treR K DNA-binding transcription factor activity
BBKJAIEB_01776 1.5e-86 treR K trehalose operon
BBKJAIEB_01777 3.3e-95 ywlG S Belongs to the UPF0340 family
BBKJAIEB_01780 4.1e-33 L PFAM Integrase, catalytic core
BBKJAIEB_01781 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
BBKJAIEB_01783 6e-58 6.3.2.2 H ergothioneine biosynthetic process
BBKJAIEB_01784 7.9e-19 6.3.2.2 H gamma-glutamylcysteine synthetase
BBKJAIEB_01785 1.2e-11 6.3.2.2 H gamma-glutamylcysteine synthetase
BBKJAIEB_01786 5.6e-87 L PFAM Integrase, catalytic core
BBKJAIEB_01787 9.7e-62 rplQ J ribosomal protein l17
BBKJAIEB_01788 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBKJAIEB_01789 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BBKJAIEB_01790 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBKJAIEB_01791 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
BBKJAIEB_01792 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBKJAIEB_01793 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
BBKJAIEB_01794 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BBKJAIEB_01795 7.4e-58 rplO J binds to the 23S rRNA
BBKJAIEB_01796 1.6e-22 rpmD J ribosomal protein l30
BBKJAIEB_01797 2.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BBKJAIEB_01798 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BBKJAIEB_01799 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BBKJAIEB_01800 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BBKJAIEB_01801 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BBKJAIEB_01802 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBKJAIEB_01803 2.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BBKJAIEB_01804 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BBKJAIEB_01805 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BBKJAIEB_01806 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
BBKJAIEB_01807 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BBKJAIEB_01808 3.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BBKJAIEB_01809 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BBKJAIEB_01810 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BBKJAIEB_01811 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBKJAIEB_01812 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
BBKJAIEB_01813 1.8e-102 rplD J Forms part of the polypeptide exit tunnel
BBKJAIEB_01814 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BBKJAIEB_01815 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
BBKJAIEB_01816 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
BBKJAIEB_01817 0.0 XK27_09800 I Acyltransferase
BBKJAIEB_01818 4.8e-35 XK27_09805 S MORN repeat protein
BBKJAIEB_01819 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBKJAIEB_01820 3.8e-102 L Transposase
BBKJAIEB_01821 7.2e-71 L Transposase
BBKJAIEB_01823 1.6e-167 cps1C S Polysaccharide biosynthesis protein
BBKJAIEB_01824 2.1e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BBKJAIEB_01825 7.7e-89 L Transposase
BBKJAIEB_01826 2.3e-87 L Transposase
BBKJAIEB_01827 8.3e-51 adk 2.7.4.3 F topology modulation protein
BBKJAIEB_01828 2.4e-23 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BBKJAIEB_01829 3.9e-114 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
BBKJAIEB_01830 4.8e-29 S Domain of unknown function (DUF4649)
BBKJAIEB_01832 7.5e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
BBKJAIEB_01833 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
BBKJAIEB_01834 2.2e-44 yrzL S Belongs to the UPF0297 family
BBKJAIEB_01835 9.5e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BBKJAIEB_01836 1.3e-45 yrzB S Belongs to the UPF0473 family
BBKJAIEB_01837 2.4e-295 ccs S the current gene model (or a revised gene model) may contain a frame shift
BBKJAIEB_01838 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
BBKJAIEB_01839 7.5e-14
BBKJAIEB_01840 3.4e-91 XK27_10930 K acetyltransferase
BBKJAIEB_01841 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBKJAIEB_01842 6.5e-145 yaaA S Belongs to the UPF0246 family
BBKJAIEB_01843 3.5e-166 XK27_01785 S cog cog1284
BBKJAIEB_01844 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
BBKJAIEB_01846 4.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
BBKJAIEB_01847 6.2e-134 metE 2.1.1.14 E Methionine synthase
BBKJAIEB_01848 1.5e-29 metE 2.1.1.14 E Methionine synthase
BBKJAIEB_01849 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
BBKJAIEB_01850 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
BBKJAIEB_01852 1.2e-48 yegS 2.7.1.107 I Diacylglycerol kinase
BBKJAIEB_01853 2.7e-95 S Hydrophobic domain protein
BBKJAIEB_01855 1e-99
BBKJAIEB_01856 1.8e-23 S Small integral membrane protein
BBKJAIEB_01857 1.7e-77 M Protein conserved in bacteria
BBKJAIEB_01858 9.2e-11 K CsbD-like
BBKJAIEB_01859 2.7e-97 nudL L hydrolase
BBKJAIEB_01860 5.5e-08 nudL L hydrolase
BBKJAIEB_01861 4e-19 K negative regulation of transcription, DNA-templated
BBKJAIEB_01862 1.7e-23 K negative regulation of transcription, DNA-templated
BBKJAIEB_01864 4.4e-18 XK27_06920 S Protein of unknown function (DUF1700)
BBKJAIEB_01865 1.2e-107 S Putative adhesin
BBKJAIEB_01866 1.5e-157 XK27_06930 V domain protein
BBKJAIEB_01867 6.4e-96 XK27_06935 K transcriptional regulator
BBKJAIEB_01868 6.6e-52 ypaA S membrane
BBKJAIEB_01869 1.8e-08
BBKJAIEB_01870 4.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BBKJAIEB_01871 8.2e-48 veg S Biofilm formation stimulator VEG
BBKJAIEB_01872 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
BBKJAIEB_01873 2e-69 rplI J binds to the 23S rRNA
BBKJAIEB_01874 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
BBKJAIEB_01875 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
BBKJAIEB_01876 1.5e-77 F NUDIX domain
BBKJAIEB_01877 1.1e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BBKJAIEB_01878 0.0 S Bacterial membrane protein, YfhO
BBKJAIEB_01879 1.7e-63 isaA GH23 M Immunodominant staphylococcal antigen A
BBKJAIEB_01880 3.1e-93 lytE M LysM domain protein
BBKJAIEB_01881 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBKJAIEB_01882 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBKJAIEB_01883 6.3e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBKJAIEB_01884 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBKJAIEB_01885 4.8e-138 ymfM S sequence-specific DNA binding
BBKJAIEB_01886 1.3e-240 ymfH S Peptidase M16
BBKJAIEB_01887 1.4e-124 ymfF S Peptidase M16
BBKJAIEB_01888 7.7e-100 ymfF S Peptidase M16
BBKJAIEB_01889 1.6e-45 yaaA S S4 domain protein YaaA
BBKJAIEB_01890 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BBKJAIEB_01891 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
BBKJAIEB_01892 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
BBKJAIEB_01893 4.2e-153 yvjA S membrane
BBKJAIEB_01894 2.2e-304 ybiT S abc transporter atp-binding protein
BBKJAIEB_01895 0.0 XK27_10405 S Bacterial membrane protein YfhO
BBKJAIEB_01899 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
BBKJAIEB_01900 6.2e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BBKJAIEB_01901 8.7e-197 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
BBKJAIEB_01902 8.5e-134 parB K Belongs to the ParB family
BBKJAIEB_01903 3.9e-122 L Transposase
BBKJAIEB_01905 5.8e-126 tnp L Transposase
BBKJAIEB_01906 2.1e-25 L Transposase and inactivated derivatives, TnpA family
BBKJAIEB_01907 1.7e-175 gadC E Psort location CytoplasmicMembrane, score 10.00
BBKJAIEB_01908 3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)