ORF_ID e_value Gene_name EC_number CAZy COGs Description
NKCFMEJF_00011 1.3e-09
NKCFMEJF_00012 7.8e-08
NKCFMEJF_00021 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NKCFMEJF_00022 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NKCFMEJF_00023 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NKCFMEJF_00024 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NKCFMEJF_00025 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NKCFMEJF_00026 9.9e-77 tspO T membrane
NKCFMEJF_00027 1.8e-206 cotI S Spore coat protein
NKCFMEJF_00028 1.8e-217 cotSA M Glycosyl transferases group 1
NKCFMEJF_00029 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
NKCFMEJF_00031 3.6e-235 ytcC M Glycosyltransferase Family 4
NKCFMEJF_00032 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NKCFMEJF_00033 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NKCFMEJF_00034 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
NKCFMEJF_00035 2.6e-132 dksA T COG1734 DnaK suppressor protein
NKCFMEJF_00036 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
NKCFMEJF_00037 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NKCFMEJF_00038 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NKCFMEJF_00039 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NKCFMEJF_00040 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NKCFMEJF_00041 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NKCFMEJF_00042 1.8e-113 troA P Belongs to the bacterial solute-binding protein 9 family
NKCFMEJF_00043 2.4e-45 troA P Belongs to the bacterial solute-binding protein 9 family
NKCFMEJF_00044 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NKCFMEJF_00045 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NKCFMEJF_00046 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NKCFMEJF_00047 1.1e-24 S Domain of Unknown Function (DUF1540)
NKCFMEJF_00048 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NKCFMEJF_00049 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
NKCFMEJF_00050 3.6e-41 rpmE2 J Ribosomal protein L31
NKCFMEJF_00051 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NKCFMEJF_00052 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NKCFMEJF_00053 3.6e-73 ytkA S YtkA-like
NKCFMEJF_00055 2.1e-76 dps P Belongs to the Dps family
NKCFMEJF_00056 5.4e-63 ytkC S Bacteriophage holin family
NKCFMEJF_00057 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NKCFMEJF_00058 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NKCFMEJF_00059 1.4e-144 ytlC P ABC transporter
NKCFMEJF_00060 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NKCFMEJF_00061 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NKCFMEJF_00062 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NKCFMEJF_00063 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NKCFMEJF_00064 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NKCFMEJF_00065 0.0 asnB 6.3.5.4 E Asparagine synthase
NKCFMEJF_00066 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NKCFMEJF_00067 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NKCFMEJF_00068 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NKCFMEJF_00069 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NKCFMEJF_00070 3.3e-106 ytqB J Putative rRNA methylase
NKCFMEJF_00071 2.1e-190 yhcC S Fe-S oxidoreductase
NKCFMEJF_00072 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NKCFMEJF_00074 5.1e-66 ytrA K GntR family transcriptional regulator
NKCFMEJF_00075 1.1e-161 ytrB P abc transporter atp-binding protein
NKCFMEJF_00076 6.1e-169 P ABC-2 family transporter protein
NKCFMEJF_00077 5.9e-148
NKCFMEJF_00078 3.1e-127 ytrE V ABC transporter, ATP-binding protein
NKCFMEJF_00079 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NKCFMEJF_00080 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_00081 5.6e-186 T PhoQ Sensor
NKCFMEJF_00082 1.1e-138 bceA V ABC transporter, ATP-binding protein
NKCFMEJF_00083 0.0 bceB V ABC transporter (permease)
NKCFMEJF_00084 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
NKCFMEJF_00085 2.1e-211 yttB EGP Major facilitator Superfamily
NKCFMEJF_00086 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NKCFMEJF_00087 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NKCFMEJF_00088 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NKCFMEJF_00089 2.1e-51 ytwF P Sulfurtransferase
NKCFMEJF_00090 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NKCFMEJF_00091 1.5e-144 amyC P ABC transporter (permease)
NKCFMEJF_00092 1.5e-169 amyD P ABC transporter
NKCFMEJF_00093 2.3e-248 msmE G Bacterial extracellular solute-binding protein
NKCFMEJF_00094 2.3e-190 msmR K Transcriptional regulator
NKCFMEJF_00095 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
NKCFMEJF_00096 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NKCFMEJF_00097 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NKCFMEJF_00098 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NKCFMEJF_00099 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NKCFMEJF_00100 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NKCFMEJF_00101 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
NKCFMEJF_00102 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NKCFMEJF_00103 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
NKCFMEJF_00104 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NKCFMEJF_00105 0.0 ytdP K Transcriptional regulator
NKCFMEJF_00106 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NKCFMEJF_00107 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NKCFMEJF_00108 4.6e-73 yteS G transport
NKCFMEJF_00109 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NKCFMEJF_00110 4.8e-117 yteU S Integral membrane protein
NKCFMEJF_00111 3.1e-26 yteV S Sporulation protein Cse60
NKCFMEJF_00112 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NKCFMEJF_00113 8.2e-232 ytfP S HI0933-like protein
NKCFMEJF_00114 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKCFMEJF_00115 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NKCFMEJF_00116 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NKCFMEJF_00117 4.3e-132 ythP V ABC transporter
NKCFMEJF_00118 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
NKCFMEJF_00119 7.2e-226 pbuO S permease
NKCFMEJF_00120 7.1e-272 pepV 3.5.1.18 E Dipeptidase
NKCFMEJF_00121 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NKCFMEJF_00122 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NKCFMEJF_00123 1.3e-165 ytlQ
NKCFMEJF_00124 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NKCFMEJF_00125 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NKCFMEJF_00126 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NKCFMEJF_00127 2e-45 ytzH S YtzH-like protein
NKCFMEJF_00128 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NKCFMEJF_00129 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NKCFMEJF_00130 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NKCFMEJF_00131 9.8e-52 ytzB S small secreted protein
NKCFMEJF_00132 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NKCFMEJF_00133 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NKCFMEJF_00134 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NKCFMEJF_00135 9.8e-149 ytpQ S Belongs to the UPF0354 family
NKCFMEJF_00136 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NKCFMEJF_00137 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NKCFMEJF_00138 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NKCFMEJF_00139 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NKCFMEJF_00140 6.6e-17 ytxH S COG4980 Gas vesicle protein
NKCFMEJF_00141 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
NKCFMEJF_00142 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NKCFMEJF_00143 1.7e-182 ccpA K catabolite control protein A
NKCFMEJF_00144 7.1e-147 motA N flagellar motor
NKCFMEJF_00145 3.8e-18 motA N flagellar motor
NKCFMEJF_00146 1.4e-125 motS N Flagellar motor protein
NKCFMEJF_00147 1.9e-225 acuC BQ histone deacetylase
NKCFMEJF_00148 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NKCFMEJF_00149 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NKCFMEJF_00150 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NKCFMEJF_00151 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NKCFMEJF_00153 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NKCFMEJF_00154 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NKCFMEJF_00155 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NKCFMEJF_00156 3.4e-109 yttP K Transcriptional regulator
NKCFMEJF_00157 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NKCFMEJF_00158 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NKCFMEJF_00159 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NKCFMEJF_00160 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
NKCFMEJF_00161 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NKCFMEJF_00162 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NKCFMEJF_00163 0.0 ytcJ S amidohydrolase
NKCFMEJF_00164 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NKCFMEJF_00165 2.4e-181 sppA OU signal peptide peptidase SppA
NKCFMEJF_00166 1.3e-87 yteJ S RDD family
NKCFMEJF_00167 5.6e-116 ytfI S Protein of unknown function (DUF2953)
NKCFMEJF_00168 8.7e-70 ytfJ S Sporulation protein YtfJ
NKCFMEJF_00169 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NKCFMEJF_00170 7e-165 ytxK 2.1.1.72 L DNA methylase
NKCFMEJF_00171 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NKCFMEJF_00172 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NKCFMEJF_00173 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NKCFMEJF_00174 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
NKCFMEJF_00176 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKCFMEJF_00177 1.7e-130 ytkL S Belongs to the UPF0173 family
NKCFMEJF_00178 2.9e-173 ytlI K LysR substrate binding domain
NKCFMEJF_00179 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
NKCFMEJF_00180 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
NKCFMEJF_00181 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
NKCFMEJF_00182 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
NKCFMEJF_00183 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
NKCFMEJF_00184 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NKCFMEJF_00185 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKCFMEJF_00186 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
NKCFMEJF_00187 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKCFMEJF_00188 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NKCFMEJF_00189 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
NKCFMEJF_00190 1.2e-158 ytnM S membrane transporter protein
NKCFMEJF_00191 8e-241 ytoI K transcriptional regulator containing CBS domains
NKCFMEJF_00192 2.4e-47 ytpI S YtpI-like protein
NKCFMEJF_00193 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NKCFMEJF_00194 9.2e-29
NKCFMEJF_00195 8.2e-69 ytrI
NKCFMEJF_00196 3.2e-56 ytrH S Sporulation protein YtrH
NKCFMEJF_00197 0.0 dnaE 2.7.7.7 L DNA polymerase
NKCFMEJF_00198 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NKCFMEJF_00199 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NKCFMEJF_00200 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NKCFMEJF_00201 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NKCFMEJF_00202 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NKCFMEJF_00203 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NKCFMEJF_00204 2.6e-192 ytvI S sporulation integral membrane protein YtvI
NKCFMEJF_00205 4.7e-71 yeaL S membrane
NKCFMEJF_00206 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NKCFMEJF_00207 1.8e-242 icd 1.1.1.42 C isocitrate
NKCFMEJF_00208 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NKCFMEJF_00209 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_00210 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NKCFMEJF_00211 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NKCFMEJF_00212 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NKCFMEJF_00213 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NKCFMEJF_00214 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NKCFMEJF_00215 8.9e-161 ytbE S reductase
NKCFMEJF_00216 4.9e-205 ytbD EGP Major facilitator Superfamily
NKCFMEJF_00217 9.9e-67 ytcD K Transcriptional regulator
NKCFMEJF_00218 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NKCFMEJF_00219 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NKCFMEJF_00220 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NKCFMEJF_00221 3.5e-266 dnaB L Membrane attachment protein
NKCFMEJF_00222 3e-173 dnaI L Primosomal protein DnaI
NKCFMEJF_00223 4.9e-111 ytxB S SNARE associated Golgi protein
NKCFMEJF_00224 3.8e-159 ytxC S YtxC-like family
NKCFMEJF_00225 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NKCFMEJF_00226 1.5e-149 ysaA S HAD-hyrolase-like
NKCFMEJF_00227 0.0 lytS 2.7.13.3 T Histidine kinase
NKCFMEJF_00228 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
NKCFMEJF_00229 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NKCFMEJF_00230 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NKCFMEJF_00232 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NKCFMEJF_00233 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NKCFMEJF_00234 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NKCFMEJF_00235 7.5e-45 ysdA S Membrane
NKCFMEJF_00236 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NKCFMEJF_00237 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
NKCFMEJF_00238 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NKCFMEJF_00239 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NKCFMEJF_00240 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NKCFMEJF_00241 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NKCFMEJF_00242 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NKCFMEJF_00243 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NKCFMEJF_00244 2.8e-254 araN G carbohydrate transport
NKCFMEJF_00245 1.4e-167 araP G carbohydrate transport
NKCFMEJF_00246 3.4e-144 araQ G transport system permease
NKCFMEJF_00247 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NKCFMEJF_00248 0.0 cstA T Carbon starvation protein
NKCFMEJF_00250 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
NKCFMEJF_00251 5.6e-258 glcF C Glycolate oxidase
NKCFMEJF_00252 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
NKCFMEJF_00253 4.4e-208 ysfB KT regulator
NKCFMEJF_00254 2.6e-32 sspI S Belongs to the SspI family
NKCFMEJF_00255 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKCFMEJF_00256 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NKCFMEJF_00257 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NKCFMEJF_00258 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NKCFMEJF_00259 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NKCFMEJF_00260 1.3e-85 cvpA S membrane protein, required for colicin V production
NKCFMEJF_00261 0.0 polX L COG1796 DNA polymerase IV (family X)
NKCFMEJF_00262 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NKCFMEJF_00263 3.6e-67 yshE S membrane
NKCFMEJF_00264 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NKCFMEJF_00265 2.7e-100 fadR K Transcriptional regulator
NKCFMEJF_00266 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NKCFMEJF_00267 1.2e-135 etfB C Electron transfer flavoprotein
NKCFMEJF_00268 4.2e-178 etfA C Electron transfer flavoprotein
NKCFMEJF_00270 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NKCFMEJF_00271 2e-52 trxA O Belongs to the thioredoxin family
NKCFMEJF_00272 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NKCFMEJF_00273 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NKCFMEJF_00274 1.2e-79 yslB S Protein of unknown function (DUF2507)
NKCFMEJF_00275 2.4e-107 sdhC C succinate dehydrogenase
NKCFMEJF_00276 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NKCFMEJF_00277 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NKCFMEJF_00278 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NKCFMEJF_00279 3.3e-30 gerE K Transcriptional regulator
NKCFMEJF_00280 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NKCFMEJF_00281 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NKCFMEJF_00282 2.9e-196 gerM S COG5401 Spore germination protein
NKCFMEJF_00283 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NKCFMEJF_00284 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NKCFMEJF_00285 1.4e-92 ysnB S Phosphoesterase
NKCFMEJF_00287 9.1e-134 ysnF S protein conserved in bacteria
NKCFMEJF_00288 7.6e-82 ysnE K acetyltransferase
NKCFMEJF_00290 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NKCFMEJF_00291 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NKCFMEJF_00292 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NKCFMEJF_00293 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NKCFMEJF_00294 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NKCFMEJF_00295 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NKCFMEJF_00296 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NKCFMEJF_00297 2.3e-187 ysoA H Tetratricopeptide repeat
NKCFMEJF_00298 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NKCFMEJF_00299 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NKCFMEJF_00300 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NKCFMEJF_00301 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NKCFMEJF_00302 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NKCFMEJF_00303 1.4e-89 ysxD
NKCFMEJF_00304 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NKCFMEJF_00305 3.6e-146 hemX O cytochrome C
NKCFMEJF_00306 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NKCFMEJF_00307 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NKCFMEJF_00308 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
NKCFMEJF_00309 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NKCFMEJF_00310 1.9e-226 spoVID M stage VI sporulation protein D
NKCFMEJF_00311 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NKCFMEJF_00312 1.6e-25
NKCFMEJF_00313 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NKCFMEJF_00314 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NKCFMEJF_00315 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NKCFMEJF_00316 1.1e-168 spoIIB S Sporulation related domain
NKCFMEJF_00317 2.8e-102 maf D septum formation protein Maf
NKCFMEJF_00318 5.9e-126 radC E Belongs to the UPF0758 family
NKCFMEJF_00319 1.8e-184 mreB D Rod shape-determining protein MreB
NKCFMEJF_00320 2.8e-157 mreC M Involved in formation and maintenance of cell shape
NKCFMEJF_00321 1.4e-84 mreD M shape-determining protein
NKCFMEJF_00322 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NKCFMEJF_00323 2.5e-144 minD D Belongs to the ParA family
NKCFMEJF_00324 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NKCFMEJF_00325 9.2e-161 spoIVFB S Stage IV sporulation protein
NKCFMEJF_00326 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NKCFMEJF_00327 4.1e-56 ysxB J ribosomal protein
NKCFMEJF_00328 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NKCFMEJF_00329 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NKCFMEJF_00330 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NKCFMEJF_00331 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NKCFMEJF_00332 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
NKCFMEJF_00333 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NKCFMEJF_00334 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
NKCFMEJF_00335 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NKCFMEJF_00336 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NKCFMEJF_00337 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NKCFMEJF_00338 9.8e-158 safA M spore coat assembly protein SafA
NKCFMEJF_00339 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKCFMEJF_00340 1.9e-127 yebC K transcriptional regulatory protein
NKCFMEJF_00341 1.8e-262 alsT E Sodium alanine symporter
NKCFMEJF_00342 2.6e-35 S Family of unknown function (DUF5412)
NKCFMEJF_00344 6.5e-119 yrzF T serine threonine protein kinase
NKCFMEJF_00345 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NKCFMEJF_00346 5.3e-253 csbX EGP Major facilitator Superfamily
NKCFMEJF_00347 4.8e-93 bofC S BofC C-terminal domain
NKCFMEJF_00348 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NKCFMEJF_00349 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NKCFMEJF_00350 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NKCFMEJF_00351 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NKCFMEJF_00352 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NKCFMEJF_00353 1.1e-38 yajC U Preprotein translocase subunit YajC
NKCFMEJF_00354 1.2e-74 yrzE S Protein of unknown function (DUF3792)
NKCFMEJF_00355 2.2e-114 yrbG S membrane
NKCFMEJF_00356 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKCFMEJF_00357 9.4e-49 yrzD S Post-transcriptional regulator
NKCFMEJF_00358 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NKCFMEJF_00359 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NKCFMEJF_00360 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NKCFMEJF_00361 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NKCFMEJF_00362 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NKCFMEJF_00363 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NKCFMEJF_00364 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NKCFMEJF_00365 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
NKCFMEJF_00367 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NKCFMEJF_00368 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NKCFMEJF_00369 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NKCFMEJF_00370 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NKCFMEJF_00371 1.2e-70 cymR K Transcriptional regulator
NKCFMEJF_00372 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
NKCFMEJF_00373 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NKCFMEJF_00374 1.4e-15 S COG0457 FOG TPR repeat
NKCFMEJF_00375 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NKCFMEJF_00376 1.8e-83 yrrD S protein conserved in bacteria
NKCFMEJF_00377 9.8e-31 yrzR
NKCFMEJF_00378 8e-08 S Protein of unknown function (DUF3918)
NKCFMEJF_00379 7.6e-107 glnP P ABC transporter
NKCFMEJF_00380 3.6e-109 gluC P ABC transporter
NKCFMEJF_00381 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
NKCFMEJF_00382 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NKCFMEJF_00383 2.7e-170 yrrI S AI-2E family transporter
NKCFMEJF_00384 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NKCFMEJF_00385 1.7e-41 yrzL S Belongs to the UPF0297 family
NKCFMEJF_00386 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NKCFMEJF_00387 1.2e-45 yrzB S Belongs to the UPF0473 family
NKCFMEJF_00388 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NKCFMEJF_00389 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
NKCFMEJF_00390 7.8e-174 yegQ O Peptidase U32
NKCFMEJF_00391 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NKCFMEJF_00392 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NKCFMEJF_00393 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NKCFMEJF_00394 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NKCFMEJF_00395 4.2e-63 yrrS S Protein of unknown function (DUF1510)
NKCFMEJF_00396 7e-27 yrzA S Protein of unknown function (DUF2536)
NKCFMEJF_00397 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NKCFMEJF_00398 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NKCFMEJF_00399 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NKCFMEJF_00400 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NKCFMEJF_00401 4.6e-35 yrhC S YrhC-like protein
NKCFMEJF_00402 1.4e-78 yrhD S Protein of unknown function (DUF1641)
NKCFMEJF_00403 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NKCFMEJF_00404 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
NKCFMEJF_00405 1.8e-142 focA P Formate nitrite
NKCFMEJF_00408 4.5e-97 yrhH Q methyltransferase
NKCFMEJF_00409 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NKCFMEJF_00410 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NKCFMEJF_00411 1.5e-46 yrhK S YrhK-like protein
NKCFMEJF_00412 0.0 yrhL I Acyltransferase family
NKCFMEJF_00413 1.7e-151 rsiV S Protein of unknown function (DUF3298)
NKCFMEJF_00414 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NKCFMEJF_00415 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
NKCFMEJF_00416 3.6e-106 yrhP E LysE type translocator
NKCFMEJF_00417 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NKCFMEJF_00418 0.0 levR K PTS system fructose IIA component
NKCFMEJF_00419 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
NKCFMEJF_00420 8.2e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NKCFMEJF_00421 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NKCFMEJF_00422 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NKCFMEJF_00423 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NKCFMEJF_00424 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NKCFMEJF_00425 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
NKCFMEJF_00426 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
NKCFMEJF_00427 4.3e-47 yraB K helix_turn_helix, mercury resistance
NKCFMEJF_00428 1.1e-49 yraD M Spore coat protein
NKCFMEJF_00429 2.6e-26 yraE
NKCFMEJF_00430 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NKCFMEJF_00431 6.4e-63 yraF M Spore coat protein
NKCFMEJF_00432 5.3e-37 yraG
NKCFMEJF_00433 1.3e-66 E Glyoxalase-like domain
NKCFMEJF_00434 2.4e-61 T sh3 domain protein
NKCFMEJF_00435 1.7e-60 T sh3 domain protein
NKCFMEJF_00436 3.2e-155 S Alpha beta hydrolase
NKCFMEJF_00437 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKCFMEJF_00438 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NKCFMEJF_00440 2.4e-206 yraM S PrpF protein
NKCFMEJF_00441 1.2e-163 yraN K Transcriptional regulator
NKCFMEJF_00442 9.5e-226 yraO C Citrate transporter
NKCFMEJF_00443 4.5e-188 yrpG C Aldo/keto reductase family
NKCFMEJF_00444 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NKCFMEJF_00445 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NKCFMEJF_00447 3e-125 yrpD S Domain of unknown function, YrpD
NKCFMEJF_00448 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NKCFMEJF_00449 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NKCFMEJF_00450 7.6e-168 aadK G Streptomycin adenylyltransferase
NKCFMEJF_00451 1.2e-91 yrdA S DinB family
NKCFMEJF_00452 1.9e-57 S Protein of unknown function (DUF2568)
NKCFMEJF_00453 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
NKCFMEJF_00455 4.1e-231 cypA C Cytochrome P450
NKCFMEJF_00456 4.1e-46 yrdF K ribonuclease inhibitor
NKCFMEJF_00457 2.2e-79 bkdR K helix_turn_helix ASNC type
NKCFMEJF_00458 3.3e-138 azlC E AzlC protein
NKCFMEJF_00459 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NKCFMEJF_00460 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
NKCFMEJF_00462 7.7e-163 gltR K LysR substrate binding domain
NKCFMEJF_00463 1.3e-66 yodA S tautomerase
NKCFMEJF_00464 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
NKCFMEJF_00465 2e-199 trkA P Oxidoreductase
NKCFMEJF_00466 5.9e-160 yrdQ K Transcriptional regulator
NKCFMEJF_00467 1.7e-171 yrdR EG EamA-like transporter family
NKCFMEJF_00468 2.1e-17 S YrzO-like protein
NKCFMEJF_00469 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NKCFMEJF_00470 1.4e-83 bltD 2.3.1.57 K FR47-like protein
NKCFMEJF_00471 3.5e-211 blt EGP Major facilitator Superfamily
NKCFMEJF_00472 4.8e-151 bltR K helix_turn_helix, mercury resistance
NKCFMEJF_00473 2.6e-108 yrkC G Cupin domain
NKCFMEJF_00474 7.8e-39 yrkD S protein conserved in bacteria
NKCFMEJF_00475 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
NKCFMEJF_00476 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
NKCFMEJF_00477 1.1e-219 yrkH P Rhodanese Homology Domain
NKCFMEJF_00478 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
NKCFMEJF_00479 4.3e-117 yrkJ S membrane transporter protein
NKCFMEJF_00480 2.8e-79 S Protein of unknown function with HXXEE motif
NKCFMEJF_00481 1.5e-97 ywrO S Flavodoxin-like fold
NKCFMEJF_00482 6e-105 yrkN K Acetyltransferase (GNAT) family
NKCFMEJF_00483 8.2e-224 yrkO P Protein of unknown function (DUF418)
NKCFMEJF_00484 1.1e-127 T Transcriptional regulator
NKCFMEJF_00485 9e-237 yrkQ T Histidine kinase
NKCFMEJF_00486 2e-68 psiE S Protein PsiE homolog
NKCFMEJF_00487 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKCFMEJF_00488 1.4e-100 yqaB E IrrE N-terminal-like domain
NKCFMEJF_00489 1e-101 adk 2.7.4.3 F adenylate kinase activity
NKCFMEJF_00491 1.1e-56 K sequence-specific DNA binding
NKCFMEJF_00492 6.5e-37 K Helix-turn-helix XRE-family like proteins
NKCFMEJF_00494 1.2e-103
NKCFMEJF_00498 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
NKCFMEJF_00499 2.5e-155 recT L RecT family
NKCFMEJF_00500 4.7e-123 3.1.3.16 L DnaD domain protein
NKCFMEJF_00501 5.9e-168 xkdC L IstB-like ATP binding protein
NKCFMEJF_00503 7.2e-74 rusA L Endodeoxyribonuclease RusA
NKCFMEJF_00504 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
NKCFMEJF_00505 1.6e-166
NKCFMEJF_00506 1.2e-79 L Transposase
NKCFMEJF_00508 6.3e-107 yqaS L DNA packaging
NKCFMEJF_00509 2.4e-253 S phage terminase, large subunit
NKCFMEJF_00510 5.9e-296 yqbA S portal protein
NKCFMEJF_00511 5.7e-169 S Phage Mu protein F like protein
NKCFMEJF_00512 2e-115
NKCFMEJF_00513 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NKCFMEJF_00514 1.9e-167 xkdG S Phage capsid family
NKCFMEJF_00515 3.6e-51 S YqbF, hypothetical protein domain
NKCFMEJF_00516 2.1e-67 S Protein of unknown function (DUF3199)
NKCFMEJF_00517 6.7e-65 yqbH S Domain of unknown function (DUF3599)
NKCFMEJF_00518 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
NKCFMEJF_00519 1.4e-77
NKCFMEJF_00520 3.2e-26
NKCFMEJF_00521 5.5e-256 xkdK S Phage tail sheath C-terminal domain
NKCFMEJF_00522 3.6e-76 xkdM S Phage tail tube protein
NKCFMEJF_00524 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
NKCFMEJF_00525 0.0 xkdO L Transglycosylase SLT domain
NKCFMEJF_00526 9e-114 xkdP S Lysin motif
NKCFMEJF_00527 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
NKCFMEJF_00528 1.8e-38 xkdR S Protein of unknown function (DUF2577)
NKCFMEJF_00529 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NKCFMEJF_00530 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NKCFMEJF_00531 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NKCFMEJF_00532 9.6e-40
NKCFMEJF_00533 2e-221
NKCFMEJF_00534 4.1e-56 xkdW S XkdW protein
NKCFMEJF_00535 1.3e-23
NKCFMEJF_00536 4.8e-165 xepA
NKCFMEJF_00537 2.6e-68 S Bacteriophage holin family
NKCFMEJF_00538 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NKCFMEJF_00540 5e-60
NKCFMEJF_00542 1.1e-104 S Suppressor of fused protein (SUFU)
NKCFMEJF_00543 3.8e-277 A Pre-toxin TG
NKCFMEJF_00546 1.6e-96 S Tetratricopeptide repeat
NKCFMEJF_00547 1.1e-152 yqcI S YqcI/YcgG family
NKCFMEJF_00548 1.6e-54 arsR K ArsR family transcriptional regulator
NKCFMEJF_00549 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKCFMEJF_00550 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
NKCFMEJF_00551 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NKCFMEJF_00552 1.4e-281 cisA2 L Recombinase
NKCFMEJF_00553 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKCFMEJF_00554 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NKCFMEJF_00555 2.3e-133 yqeB
NKCFMEJF_00556 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NKCFMEJF_00557 4.7e-106 yqeD S SNARE associated Golgi protein
NKCFMEJF_00558 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NKCFMEJF_00559 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NKCFMEJF_00561 5.3e-95 yqeG S hydrolase of the HAD superfamily
NKCFMEJF_00562 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NKCFMEJF_00563 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NKCFMEJF_00564 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NKCFMEJF_00565 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NKCFMEJF_00566 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NKCFMEJF_00567 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NKCFMEJF_00568 2.9e-139 yqeM Q Methyltransferase
NKCFMEJF_00569 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKCFMEJF_00570 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NKCFMEJF_00571 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NKCFMEJF_00572 0.0 comEC S Competence protein ComEC
NKCFMEJF_00573 4.1e-15 S YqzM-like protein
NKCFMEJF_00574 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NKCFMEJF_00575 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NKCFMEJF_00576 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NKCFMEJF_00577 6.9e-223 spoIIP M stage II sporulation protein P
NKCFMEJF_00578 1e-54 yqxA S Protein of unknown function (DUF3679)
NKCFMEJF_00579 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NKCFMEJF_00580 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
NKCFMEJF_00581 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NKCFMEJF_00582 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NKCFMEJF_00583 0.0 dnaK O Heat shock 70 kDa protein
NKCFMEJF_00584 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NKCFMEJF_00585 5.4e-175 prmA J Methylates ribosomal protein L11
NKCFMEJF_00586 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NKCFMEJF_00587 1e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NKCFMEJF_00588 1.6e-158 yqeW P COG1283 Na phosphate symporter
NKCFMEJF_00589 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NKCFMEJF_00590 2.5e-61 yqeY S Yqey-like protein
NKCFMEJF_00591 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NKCFMEJF_00592 4.3e-122 yqfA S UPF0365 protein
NKCFMEJF_00593 6e-25 yqfB
NKCFMEJF_00594 2.7e-45 yqfC S sporulation protein YqfC
NKCFMEJF_00595 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NKCFMEJF_00596 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
NKCFMEJF_00598 0.0 yqfF S membrane-associated HD superfamily hydrolase
NKCFMEJF_00599 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NKCFMEJF_00600 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NKCFMEJF_00601 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NKCFMEJF_00602 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NKCFMEJF_00603 8.4e-19 S YqzL-like protein
NKCFMEJF_00604 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
NKCFMEJF_00605 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NKCFMEJF_00606 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NKCFMEJF_00607 4.5e-112 ccpN K CBS domain
NKCFMEJF_00608 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NKCFMEJF_00609 4.5e-88 yaiI S Belongs to the UPF0178 family
NKCFMEJF_00610 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NKCFMEJF_00611 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NKCFMEJF_00612 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NKCFMEJF_00613 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
NKCFMEJF_00614 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NKCFMEJF_00615 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NKCFMEJF_00616 2.9e-14 yqfQ S YqfQ-like protein
NKCFMEJF_00617 2.4e-43 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NKCFMEJF_00618 2.6e-172 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NKCFMEJF_00619 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NKCFMEJF_00620 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NKCFMEJF_00621 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NKCFMEJF_00622 1.9e-77 zur P Belongs to the Fur family
NKCFMEJF_00623 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NKCFMEJF_00624 4.3e-62 yqfX S membrane
NKCFMEJF_00625 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NKCFMEJF_00626 5.2e-47 yqfZ M LysM domain
NKCFMEJF_00627 2.2e-75 yqgA
NKCFMEJF_00628 8.5e-134 yqgB S Protein of unknown function (DUF1189)
NKCFMEJF_00629 4e-73 yqgC S protein conserved in bacteria
NKCFMEJF_00630 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NKCFMEJF_00631 2.5e-231 yqgE EGP Major facilitator superfamily
NKCFMEJF_00632 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NKCFMEJF_00633 5.3e-151 pstS P Phosphate
NKCFMEJF_00634 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
NKCFMEJF_00635 4.4e-158 pstA P Phosphate transport system permease
NKCFMEJF_00636 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NKCFMEJF_00637 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NKCFMEJF_00638 1.9e-75 yqzC S YceG-like family
NKCFMEJF_00639 9.2e-51 yqzD
NKCFMEJF_00641 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NKCFMEJF_00642 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NKCFMEJF_00643 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NKCFMEJF_00644 2.5e-09 yqgO
NKCFMEJF_00645 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NKCFMEJF_00646 3.1e-33 yqgQ S Protein conserved in bacteria
NKCFMEJF_00647 5.2e-181 glcK 2.7.1.2 G Glucokinase
NKCFMEJF_00648 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NKCFMEJF_00649 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NKCFMEJF_00650 2.7e-199 yqgU
NKCFMEJF_00651 6.9e-50 yqgV S Thiamine-binding protein
NKCFMEJF_00652 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NKCFMEJF_00653 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NKCFMEJF_00654 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NKCFMEJF_00655 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NKCFMEJF_00657 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKCFMEJF_00658 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NKCFMEJF_00659 7.2e-175 corA P Mg2 transporter protein
NKCFMEJF_00661 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NKCFMEJF_00662 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
NKCFMEJF_00663 1.4e-47 comGC U Required for transformation and DNA binding
NKCFMEJF_00664 4.4e-71 gspH NU protein transport across the cell outer membrane
NKCFMEJF_00665 1.1e-59 comGE
NKCFMEJF_00666 5.5e-49 comGF U Putative Competence protein ComGF
NKCFMEJF_00667 3.7e-42 S ComG operon protein 7
NKCFMEJF_00668 1.4e-26 yqzE S YqzE-like protein
NKCFMEJF_00669 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NKCFMEJF_00670 2.1e-116 yqxM
NKCFMEJF_00671 6.7e-59 sipW 3.4.21.89 U Signal peptidase
NKCFMEJF_00672 2.3e-142 tasA S Cell division protein FtsN
NKCFMEJF_00673 1e-54 sinR K transcriptional
NKCFMEJF_00674 1.2e-24 sinI S Anti-repressor SinI
NKCFMEJF_00675 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
NKCFMEJF_00676 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NKCFMEJF_00677 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NKCFMEJF_00678 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NKCFMEJF_00679 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NKCFMEJF_00680 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NKCFMEJF_00681 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NKCFMEJF_00682 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NKCFMEJF_00683 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
NKCFMEJF_00684 2.2e-61 yqhP
NKCFMEJF_00685 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
NKCFMEJF_00686 2.3e-93 yqhR S Conserved membrane protein YqhR
NKCFMEJF_00687 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NKCFMEJF_00688 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NKCFMEJF_00689 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NKCFMEJF_00690 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NKCFMEJF_00691 1.2e-171 spoIIIAA S stage III sporulation protein AA
NKCFMEJF_00692 2.9e-85 spoIIIAB S Stage III sporulation protein
NKCFMEJF_00693 7.6e-29 spoIIIAC S stage III sporulation protein AC
NKCFMEJF_00694 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NKCFMEJF_00695 1.3e-197 spoIIIAE S stage III sporulation protein AE
NKCFMEJF_00696 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NKCFMEJF_00697 6.9e-103 spoIIIAG S stage III sporulation protein AG
NKCFMEJF_00698 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NKCFMEJF_00699 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NKCFMEJF_00700 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NKCFMEJF_00701 2.1e-67 yqhY S protein conserved in bacteria
NKCFMEJF_00702 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NKCFMEJF_00703 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NKCFMEJF_00704 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NKCFMEJF_00705 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NKCFMEJF_00706 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NKCFMEJF_00707 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NKCFMEJF_00708 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NKCFMEJF_00709 1.7e-78 argR K Regulates arginine biosynthesis genes
NKCFMEJF_00710 0.0 recN L May be involved in recombinational repair of damaged DNA
NKCFMEJF_00711 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NKCFMEJF_00712 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NKCFMEJF_00714 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NKCFMEJF_00715 5.9e-27
NKCFMEJF_00716 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NKCFMEJF_00717 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NKCFMEJF_00718 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
NKCFMEJF_00719 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
NKCFMEJF_00720 1.8e-212 mmgC I acyl-CoA dehydrogenase
NKCFMEJF_00721 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NKCFMEJF_00722 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NKCFMEJF_00723 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NKCFMEJF_00724 4e-34 yqzF S Protein of unknown function (DUF2627)
NKCFMEJF_00725 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NKCFMEJF_00726 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NKCFMEJF_00727 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NKCFMEJF_00728 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NKCFMEJF_00729 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NKCFMEJF_00730 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NKCFMEJF_00731 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NKCFMEJF_00732 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NKCFMEJF_00733 2.6e-152 bmrR K helix_turn_helix, mercury resistance
NKCFMEJF_00734 7.9e-208 norA EGP Major facilitator Superfamily
NKCFMEJF_00735 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NKCFMEJF_00736 9.3e-77 yqiW S Belongs to the UPF0403 family
NKCFMEJF_00737 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
NKCFMEJF_00738 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NKCFMEJF_00739 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NKCFMEJF_00740 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
NKCFMEJF_00741 1.4e-98 yqjB S protein conserved in bacteria
NKCFMEJF_00743 8e-45 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NKCFMEJF_00744 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NKCFMEJF_00745 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NKCFMEJF_00746 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
NKCFMEJF_00747 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NKCFMEJF_00748 4.5e-24 yqzJ
NKCFMEJF_00749 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKCFMEJF_00750 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NKCFMEJF_00751 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NKCFMEJF_00752 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NKCFMEJF_00753 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NKCFMEJF_00754 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NKCFMEJF_00755 0.0 rocB E arginine degradation protein
NKCFMEJF_00756 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKCFMEJF_00757 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NKCFMEJF_00758 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_00759 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NKCFMEJF_00760 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NKCFMEJF_00761 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKCFMEJF_00763 5.2e-226 yqjV G Major Facilitator Superfamily
NKCFMEJF_00765 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKCFMEJF_00766 2.2e-49 S YolD-like protein
NKCFMEJF_00767 3.6e-87 yqjY K acetyltransferase
NKCFMEJF_00768 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NKCFMEJF_00769 4.7e-196 yqkA K GrpB protein
NKCFMEJF_00770 2.8e-54 yqkB S Belongs to the HesB IscA family
NKCFMEJF_00771 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NKCFMEJF_00772 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NKCFMEJF_00773 4e-14 yqkE S Protein of unknown function (DUF3886)
NKCFMEJF_00774 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NKCFMEJF_00776 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NKCFMEJF_00777 2.5e-222 yqxK 3.6.4.12 L DNA helicase
NKCFMEJF_00778 4.5e-58 ansR K Transcriptional regulator
NKCFMEJF_00779 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
NKCFMEJF_00780 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NKCFMEJF_00781 3.1e-235 mleN C Na H antiporter
NKCFMEJF_00782 5.5e-242 mleA 1.1.1.38 C malic enzyme
NKCFMEJF_00783 2e-32 yqkK
NKCFMEJF_00784 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NKCFMEJF_00785 2.4e-80 fur P Belongs to the Fur family
NKCFMEJF_00786 3.7e-37 S Protein of unknown function (DUF4227)
NKCFMEJF_00787 2.6e-166 xerD L recombinase XerD
NKCFMEJF_00788 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NKCFMEJF_00789 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NKCFMEJF_00790 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NKCFMEJF_00791 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NKCFMEJF_00792 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NKCFMEJF_00793 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKCFMEJF_00794 7.4e-112 spoVAA S Stage V sporulation protein AA
NKCFMEJF_00795 1e-67 spoVAB S Stage V sporulation protein AB
NKCFMEJF_00796 2.3e-78 spoVAC S stage V sporulation protein AC
NKCFMEJF_00797 9e-192 spoVAD I Stage V sporulation protein AD
NKCFMEJF_00798 1.1e-56 spoVAEB S stage V sporulation protein
NKCFMEJF_00799 1.4e-110 spoVAEA S stage V sporulation protein
NKCFMEJF_00800 5.2e-273 spoVAF EG Stage V sporulation protein AF
NKCFMEJF_00801 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NKCFMEJF_00802 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NKCFMEJF_00803 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_00804 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_00805 2.1e-179 fhuD P ABC transporter
NKCFMEJF_00807 2.6e-237 yvsH E Arginine ornithine antiporter
NKCFMEJF_00808 6.5e-16 S Small spore protein J (Spore_SspJ)
NKCFMEJF_00809 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NKCFMEJF_00810 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NKCFMEJF_00811 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NKCFMEJF_00812 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NKCFMEJF_00813 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
NKCFMEJF_00814 9.1e-158 yvgN S reductase
NKCFMEJF_00815 5.4e-86 yvgO
NKCFMEJF_00816 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NKCFMEJF_00817 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NKCFMEJF_00818 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NKCFMEJF_00819 0.0 helD 3.6.4.12 L DNA helicase
NKCFMEJF_00820 4.1e-107 yvgT S membrane
NKCFMEJF_00821 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
NKCFMEJF_00822 1.6e-104 bdbD O Thioredoxin
NKCFMEJF_00823 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NKCFMEJF_00824 0.0 copA 3.6.3.54 P P-type ATPase
NKCFMEJF_00825 1.5e-29 copZ P Copper resistance protein CopZ
NKCFMEJF_00826 2.2e-48 csoR S transcriptional
NKCFMEJF_00827 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
NKCFMEJF_00828 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKCFMEJF_00829 0.0 yvaC S Fusaric acid resistance protein-like
NKCFMEJF_00830 5.7e-73 yvaD S Family of unknown function (DUF5360)
NKCFMEJF_00831 2.8e-55 yvaE P Small Multidrug Resistance protein
NKCFMEJF_00832 4.1e-101 K Bacterial regulatory proteins, tetR family
NKCFMEJF_00833 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_00835 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NKCFMEJF_00836 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NKCFMEJF_00837 5.6e-143 est 3.1.1.1 S Carboxylesterase
NKCFMEJF_00838 2.4e-23 secG U Preprotein translocase subunit SecG
NKCFMEJF_00839 3.7e-153 yvaM S Serine aminopeptidase, S33
NKCFMEJF_00840 7.5e-36 yvzC K Transcriptional
NKCFMEJF_00841 4e-69 K transcriptional
NKCFMEJF_00842 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
NKCFMEJF_00843 2.2e-54 yodB K transcriptional
NKCFMEJF_00844 4.2e-226 NT chemotaxis protein
NKCFMEJF_00845 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NKCFMEJF_00846 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NKCFMEJF_00847 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NKCFMEJF_00848 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NKCFMEJF_00849 8.7e-61 yvbF K Belongs to the GbsR family
NKCFMEJF_00850 7.9e-13 S Sporulation delaying protein SdpA
NKCFMEJF_00851 7.6e-172
NKCFMEJF_00852 4.4e-08
NKCFMEJF_00853 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NKCFMEJF_00854 4.5e-45 sdpR K transcriptional
NKCFMEJF_00855 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NKCFMEJF_00856 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NKCFMEJF_00857 3.9e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NKCFMEJF_00858 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NKCFMEJF_00859 4.2e-98 yvbF K Belongs to the GbsR family
NKCFMEJF_00860 6.4e-103 yvbG U UPF0056 membrane protein
NKCFMEJF_00861 8.6e-113 yvbH S YvbH-like oligomerisation region
NKCFMEJF_00862 4.2e-124 exoY M Membrane
NKCFMEJF_00863 0.0 tcaA S response to antibiotic
NKCFMEJF_00864 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
NKCFMEJF_00865 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NKCFMEJF_00866 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NKCFMEJF_00867 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NKCFMEJF_00868 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NKCFMEJF_00869 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NKCFMEJF_00870 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NKCFMEJF_00871 1.6e-252 araE EGP Major facilitator Superfamily
NKCFMEJF_00872 5.5e-203 araR K transcriptional
NKCFMEJF_00873 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKCFMEJF_00874 3.9e-159 yvbU K Transcriptional regulator
NKCFMEJF_00875 8.5e-157 yvbV EG EamA-like transporter family
NKCFMEJF_00876 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NKCFMEJF_00877 4.3e-197 yvbX S Glycosyl hydrolase
NKCFMEJF_00878 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NKCFMEJF_00879 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NKCFMEJF_00880 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NKCFMEJF_00881 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKCFMEJF_00882 8.9e-201 desK 2.7.13.3 T Histidine kinase
NKCFMEJF_00883 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
NKCFMEJF_00884 1.1e-161 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NKCFMEJF_00885 2.6e-157 rsbQ S Alpha/beta hydrolase family
NKCFMEJF_00886 1.4e-199 rsbU 3.1.3.3 T response regulator
NKCFMEJF_00887 2.6e-252 galA 3.2.1.89 G arabinogalactan
NKCFMEJF_00888 0.0 lacA 3.2.1.23 G beta-galactosidase
NKCFMEJF_00889 3.2e-150 ganQ P transport
NKCFMEJF_00890 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
NKCFMEJF_00891 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
NKCFMEJF_00892 1.8e-184 lacR K Transcriptional regulator
NKCFMEJF_00893 6.6e-111 yvfI K COG2186 Transcriptional regulators
NKCFMEJF_00894 1.4e-309 yvfH C L-lactate permease
NKCFMEJF_00895 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NKCFMEJF_00896 1e-31 yvfG S YvfG protein
NKCFMEJF_00897 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
NKCFMEJF_00898 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NKCFMEJF_00899 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NKCFMEJF_00900 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NKCFMEJF_00901 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKCFMEJF_00902 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NKCFMEJF_00903 3.6e-207 epsI GM pyruvyl transferase
NKCFMEJF_00904 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
NKCFMEJF_00905 4.8e-207 epsG S EpsG family
NKCFMEJF_00906 4e-220 epsF GT4 M Glycosyl transferases group 1
NKCFMEJF_00907 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NKCFMEJF_00908 2e-224 epsD GT4 M Glycosyl transferase 4-like
NKCFMEJF_00909 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NKCFMEJF_00910 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NKCFMEJF_00911 4e-122 ywqC M biosynthesis protein
NKCFMEJF_00912 5.7e-77 slr K transcriptional
NKCFMEJF_00913 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NKCFMEJF_00915 4.6e-93 padC Q Phenolic acid decarboxylase
NKCFMEJF_00916 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
NKCFMEJF_00917 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NKCFMEJF_00918 9.6e-266 pbpE V Beta-lactamase
NKCFMEJF_00919 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NKCFMEJF_00920 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NKCFMEJF_00921 1.8e-295 yveA E amino acid
NKCFMEJF_00922 2.6e-106 yvdT K Transcriptional regulator
NKCFMEJF_00923 6.7e-51 ykkC P Small Multidrug Resistance protein
NKCFMEJF_00924 4.1e-50 sugE P Small Multidrug Resistance protein
NKCFMEJF_00925 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
NKCFMEJF_00926 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
NKCFMEJF_00927 1.5e-183 S Patatin-like phospholipase
NKCFMEJF_00929 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NKCFMEJF_00930 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NKCFMEJF_00931 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NKCFMEJF_00932 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NKCFMEJF_00933 1.2e-158 malA S Protein of unknown function (DUF1189)
NKCFMEJF_00934 7.8e-149 malD P transport
NKCFMEJF_00935 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
NKCFMEJF_00936 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NKCFMEJF_00937 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NKCFMEJF_00938 3.6e-174 yvdE K Transcriptional regulator
NKCFMEJF_00939 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NKCFMEJF_00940 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
NKCFMEJF_00941 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NKCFMEJF_00942 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NKCFMEJF_00943 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKCFMEJF_00944 0.0 yxdM V ABC transporter (permease)
NKCFMEJF_00945 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NKCFMEJF_00946 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NKCFMEJF_00947 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_00948 1.8e-33
NKCFMEJF_00949 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NKCFMEJF_00950 1.6e-36 crh G Phosphocarrier protein Chr
NKCFMEJF_00951 1.4e-170 whiA K May be required for sporulation
NKCFMEJF_00952 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NKCFMEJF_00953 5.7e-166 rapZ S Displays ATPase and GTPase activities
NKCFMEJF_00954 9.2e-44 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NKCFMEJF_00955 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NKCFMEJF_00956 1.4e-102 usp CBM50 M protein conserved in bacteria
NKCFMEJF_00957 2.4e-278 S COG0457 FOG TPR repeat
NKCFMEJF_00958 0.0 msbA2 3.6.3.44 V ABC transporter
NKCFMEJF_00960 0.0
NKCFMEJF_00961 4.6e-121
NKCFMEJF_00962 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NKCFMEJF_00963 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NKCFMEJF_00964 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NKCFMEJF_00965 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NKCFMEJF_00966 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NKCFMEJF_00967 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NKCFMEJF_00968 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NKCFMEJF_00969 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NKCFMEJF_00970 4.5e-140 yvpB NU protein conserved in bacteria
NKCFMEJF_00971 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NKCFMEJF_00972 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NKCFMEJF_00973 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NKCFMEJF_00974 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
NKCFMEJF_00975 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NKCFMEJF_00976 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NKCFMEJF_00977 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NKCFMEJF_00978 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NKCFMEJF_00979 3.6e-134 yvoA K transcriptional
NKCFMEJF_00980 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NKCFMEJF_00981 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NKCFMEJF_00982 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
NKCFMEJF_00983 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
NKCFMEJF_00984 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NKCFMEJF_00985 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
NKCFMEJF_00986 2.7e-203 yvmA EGP Major facilitator Superfamily
NKCFMEJF_00987 1.2e-50 yvlD S Membrane
NKCFMEJF_00988 2.6e-26 pspB KT PspC domain
NKCFMEJF_00989 3.4e-168 yvlB S Putative adhesin
NKCFMEJF_00990 8e-49 yvlA
NKCFMEJF_00991 6.7e-34 yvkN
NKCFMEJF_00992 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NKCFMEJF_00993 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NKCFMEJF_00994 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NKCFMEJF_00995 1.2e-30 csbA S protein conserved in bacteria
NKCFMEJF_00996 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NKCFMEJF_00997 7e-101 yvkB K Transcriptional regulator
NKCFMEJF_00998 7.9e-228 yvkA EGP Major facilitator Superfamily
NKCFMEJF_00999 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKCFMEJF_01000 1e-54 swrA S Swarming motility protein
NKCFMEJF_01001 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NKCFMEJF_01002 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NKCFMEJF_01003 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NKCFMEJF_01004 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
NKCFMEJF_01005 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NKCFMEJF_01006 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NKCFMEJF_01007 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NKCFMEJF_01008 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NKCFMEJF_01009 2.8e-66
NKCFMEJF_01010 1.9e-08 fliT S bacterial-type flagellum organization
NKCFMEJF_01011 2.9e-69 fliS N flagellar protein FliS
NKCFMEJF_01012 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NKCFMEJF_01013 6.1e-57 flaG N flagellar protein FlaG
NKCFMEJF_01014 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NKCFMEJF_01015 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NKCFMEJF_01016 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NKCFMEJF_01017 2.6e-50 yviE
NKCFMEJF_01018 1.1e-156 flgL N Belongs to the bacterial flagellin family
NKCFMEJF_01019 1.2e-264 flgK N flagellar hook-associated protein
NKCFMEJF_01020 2.4e-78 flgN NOU FlgN protein
NKCFMEJF_01021 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
NKCFMEJF_01022 7e-74 yvyF S flagellar protein
NKCFMEJF_01023 2.7e-129 comFC S Phosphoribosyl transferase domain
NKCFMEJF_01024 5.7e-46 comFB S Late competence development protein ComFB
NKCFMEJF_01025 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NKCFMEJF_01026 7.3e-155 degV S protein conserved in bacteria
NKCFMEJF_01027 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKCFMEJF_01028 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NKCFMEJF_01029 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NKCFMEJF_01030 6e-163 yvhJ K Transcriptional regulator
NKCFMEJF_01031 2.2e-149 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NKCFMEJF_01032 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NKCFMEJF_01033 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
NKCFMEJF_01034 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
NKCFMEJF_01035 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
NKCFMEJF_01036 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NKCFMEJF_01037 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NKCFMEJF_01038 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKCFMEJF_01039 2.7e-78 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NKCFMEJF_01040 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NKCFMEJF_01041 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NKCFMEJF_01042 6e-38
NKCFMEJF_01043 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NKCFMEJF_01044 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NKCFMEJF_01045 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NKCFMEJF_01046 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NKCFMEJF_01047 8.1e-257 ggaA M Glycosyltransferase like family 2
NKCFMEJF_01049 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NKCFMEJF_01050 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NKCFMEJF_01051 1.1e-150 tagG GM Transport permease protein
NKCFMEJF_01052 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NKCFMEJF_01053 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
NKCFMEJF_01054 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NKCFMEJF_01055 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NKCFMEJF_01056 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NKCFMEJF_01057 1.2e-260
NKCFMEJF_01058 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NKCFMEJF_01059 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NKCFMEJF_01060 3.5e-266 gerBA EG Spore germination protein
NKCFMEJF_01061 7.5e-200 gerBB E Spore germination protein
NKCFMEJF_01062 7.6e-216 gerAC S Spore germination protein
NKCFMEJF_01063 1.9e-248 ywtG EGP Major facilitator Superfamily
NKCFMEJF_01064 8.4e-171 ywtF K Transcriptional regulator
NKCFMEJF_01065 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NKCFMEJF_01066 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NKCFMEJF_01067 3.6e-21 ywtC
NKCFMEJF_01068 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NKCFMEJF_01069 8.6e-70 pgsC S biosynthesis protein
NKCFMEJF_01070 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NKCFMEJF_01071 1.5e-180 rbsR K transcriptional
NKCFMEJF_01072 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NKCFMEJF_01073 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NKCFMEJF_01074 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NKCFMEJF_01075 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NKCFMEJF_01076 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NKCFMEJF_01077 9.6e-71 batE T Sh3 type 3 domain protein
NKCFMEJF_01078 3.6e-48 ywsA S Protein of unknown function (DUF3892)
NKCFMEJF_01079 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NKCFMEJF_01080 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NKCFMEJF_01081 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NKCFMEJF_01082 1.1e-169 alsR K LysR substrate binding domain
NKCFMEJF_01083 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NKCFMEJF_01084 7.5e-126 ywrJ
NKCFMEJF_01085 7.6e-131 cotB
NKCFMEJF_01086 1.2e-210 cotH M Spore Coat
NKCFMEJF_01087 3.7e-12
NKCFMEJF_01088 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NKCFMEJF_01089 2.9e-54 S Domain of unknown function (DUF4181)
NKCFMEJF_01090 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NKCFMEJF_01091 2.1e-82 ywrC K Transcriptional regulator
NKCFMEJF_01092 2.4e-104 ywrB P Chromate transporter
NKCFMEJF_01093 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
NKCFMEJF_01095 2.7e-102 ywqN S NAD(P)H-dependent
NKCFMEJF_01096 2.9e-162 K Transcriptional regulator
NKCFMEJF_01097 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NKCFMEJF_01098 1.7e-52 S MORN repeat variant
NKCFMEJF_01099 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
NKCFMEJF_01100 1.3e-38 ywqI S Family of unknown function (DUF5344)
NKCFMEJF_01101 3.3e-15 S Domain of unknown function (DUF5082)
NKCFMEJF_01102 3.4e-154 ywqG S Domain of unknown function (DUF1963)
NKCFMEJF_01103 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NKCFMEJF_01104 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NKCFMEJF_01105 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NKCFMEJF_01106 2e-116 ywqC M biosynthesis protein
NKCFMEJF_01107 1.2e-17
NKCFMEJF_01108 3.8e-309 ywqB S SWIM zinc finger
NKCFMEJF_01109 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NKCFMEJF_01110 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NKCFMEJF_01111 6.1e-85 glcR K COG1349 Transcriptional regulators of sugar metabolism
NKCFMEJF_01112 1.7e-34 glcR K COG1349 Transcriptional regulators of sugar metabolism
NKCFMEJF_01113 9.8e-58 ssbB L Single-stranded DNA-binding protein
NKCFMEJF_01114 1.3e-66 ywpG
NKCFMEJF_01115 1.1e-66 ywpF S YwpF-like protein
NKCFMEJF_01116 8e-51 srtA 3.4.22.70 M Sortase family
NKCFMEJF_01117 1.9e-153 ywpD T Histidine kinase
NKCFMEJF_01118 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NKCFMEJF_01119 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NKCFMEJF_01120 2.1e-199 S aspartate phosphatase
NKCFMEJF_01121 1.5e-141 flhP N flagellar basal body
NKCFMEJF_01122 6.9e-126 flhO N flagellar basal body
NKCFMEJF_01123 3.5e-180 mbl D Rod shape-determining protein
NKCFMEJF_01124 3e-44 spoIIID K Stage III sporulation protein D
NKCFMEJF_01125 2.1e-70 ywoH K COG1846 Transcriptional regulators
NKCFMEJF_01126 2.7e-211 ywoG EGP Major facilitator Superfamily
NKCFMEJF_01127 1.2e-231 ywoF P Right handed beta helix region
NKCFMEJF_01128 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NKCFMEJF_01129 4.4e-242 ywoD EGP Major facilitator superfamily
NKCFMEJF_01130 4e-104 phzA Q Isochorismatase family
NKCFMEJF_01131 1.2e-77
NKCFMEJF_01132 2.5e-225 amt P Ammonium transporter
NKCFMEJF_01133 1.6e-58 nrgB K Belongs to the P(II) protein family
NKCFMEJF_01134 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NKCFMEJF_01135 3.5e-73 ywnJ S VanZ like family
NKCFMEJF_01136 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NKCFMEJF_01137 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NKCFMEJF_01138 2.7e-14 ywnC S Family of unknown function (DUF5362)
NKCFMEJF_01139 2.2e-70 ywnF S Family of unknown function (DUF5392)
NKCFMEJF_01140 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NKCFMEJF_01141 4.1e-144 mta K transcriptional
NKCFMEJF_01142 2.6e-59 ywnC S Family of unknown function (DUF5362)
NKCFMEJF_01143 1.6e-114 ywnB S NAD(P)H-binding
NKCFMEJF_01144 1.7e-64 ywnA K Transcriptional regulator
NKCFMEJF_01145 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NKCFMEJF_01146 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NKCFMEJF_01147 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NKCFMEJF_01149 3.8e-11 csbD K CsbD-like
NKCFMEJF_01150 3e-84 ywmF S Peptidase M50
NKCFMEJF_01151 1.3e-103 S response regulator aspartate phosphatase
NKCFMEJF_01152 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NKCFMEJF_01153 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NKCFMEJF_01155 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NKCFMEJF_01156 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NKCFMEJF_01157 2e-178 spoIID D Stage II sporulation protein D
NKCFMEJF_01158 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKCFMEJF_01159 1.6e-134 ywmB S TATA-box binding
NKCFMEJF_01160 1.3e-32 ywzB S membrane
NKCFMEJF_01161 4.3e-88 ywmA
NKCFMEJF_01162 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NKCFMEJF_01163 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NKCFMEJF_01164 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NKCFMEJF_01165 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NKCFMEJF_01166 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NKCFMEJF_01167 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NKCFMEJF_01168 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NKCFMEJF_01169 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NKCFMEJF_01170 2.5e-62 atpI S ATP synthase
NKCFMEJF_01171 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NKCFMEJF_01172 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NKCFMEJF_01173 7.2e-95 ywlG S Belongs to the UPF0340 family
NKCFMEJF_01174 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NKCFMEJF_01175 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NKCFMEJF_01176 1.7e-91 mntP P Probably functions as a manganese efflux pump
NKCFMEJF_01177 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NKCFMEJF_01178 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NKCFMEJF_01179 6.1e-112 spoIIR S stage II sporulation protein R
NKCFMEJF_01180 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
NKCFMEJF_01182 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NKCFMEJF_01183 1.5e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NKCFMEJF_01184 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKCFMEJF_01185 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NKCFMEJF_01186 8.6e-160 ywkB S Membrane transport protein
NKCFMEJF_01187 0.0 sfcA 1.1.1.38 C malic enzyme
NKCFMEJF_01188 2.4e-104 tdk 2.7.1.21 F thymidine kinase
NKCFMEJF_01189 1.1e-32 rpmE J Binds the 23S rRNA
NKCFMEJF_01190 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NKCFMEJF_01191 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NKCFMEJF_01192 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NKCFMEJF_01193 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NKCFMEJF_01194 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NKCFMEJF_01195 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NKCFMEJF_01196 2.4e-92 ywjG S Domain of unknown function (DUF2529)
NKCFMEJF_01197 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NKCFMEJF_01198 1.1e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NKCFMEJF_01199 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NKCFMEJF_01200 0.0 fadF C COG0247 Fe-S oxidoreductase
NKCFMEJF_01201 4.6e-63 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NKCFMEJF_01202 2e-140 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NKCFMEJF_01203 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NKCFMEJF_01204 2.7e-42 ywjC
NKCFMEJF_01205 4.8e-96 ywjB H RibD C-terminal domain
NKCFMEJF_01206 0.0 ywjA V ABC transporter
NKCFMEJF_01207 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NKCFMEJF_01208 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
NKCFMEJF_01209 2.4e-98 narJ 1.7.5.1 C nitrate reductase
NKCFMEJF_01210 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
NKCFMEJF_01211 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKCFMEJF_01212 7e-86 arfM T cyclic nucleotide binding
NKCFMEJF_01213 4.3e-140 ywiC S YwiC-like protein
NKCFMEJF_01214 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
NKCFMEJF_01215 9.8e-214 narK P COG2223 Nitrate nitrite transporter
NKCFMEJF_01216 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NKCFMEJF_01217 4.7e-73 ywiB S protein conserved in bacteria
NKCFMEJF_01218 1e-07 S Bacteriocin subtilosin A
NKCFMEJF_01219 2.6e-271 C Fe-S oxidoreductases
NKCFMEJF_01221 3.3e-132 cbiO V ABC transporter
NKCFMEJF_01222 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NKCFMEJF_01223 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
NKCFMEJF_01224 1.2e-249 L Peptidase, M16
NKCFMEJF_01226 2.9e-249 ywhL CO amine dehydrogenase activity
NKCFMEJF_01227 2.5e-205 ywhK CO amine dehydrogenase activity
NKCFMEJF_01228 2.3e-79 S aspartate phosphatase
NKCFMEJF_01230 1e-84 ywhH S Aminoacyl-tRNA editing domain
NKCFMEJF_01231 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NKCFMEJF_01232 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NKCFMEJF_01233 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NKCFMEJF_01234 5.2e-95 ywhD S YwhD family
NKCFMEJF_01235 5.1e-119 ywhC S Peptidase family M50
NKCFMEJF_01236 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NKCFMEJF_01237 3.3e-71 ywhA K Transcriptional regulator
NKCFMEJF_01238 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NKCFMEJF_01243 7.8e-08
NKCFMEJF_01251 2e-08
NKCFMEJF_01255 2.7e-143 spo0M S COG4326 Sporulation control protein
NKCFMEJF_01256 3e-27
NKCFMEJF_01257 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NKCFMEJF_01258 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NKCFMEJF_01259 1.9e-266 ygaK C Berberine and berberine like
NKCFMEJF_01261 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NKCFMEJF_01262 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NKCFMEJF_01263 1.7e-171 ssuA M Sulfonate ABC transporter
NKCFMEJF_01264 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NKCFMEJF_01265 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NKCFMEJF_01267 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NKCFMEJF_01268 4.1e-78 ygaO
NKCFMEJF_01269 4.4e-29 K Transcriptional regulator
NKCFMEJF_01271 7.9e-114 yhzB S B3/4 domain
NKCFMEJF_01272 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NKCFMEJF_01273 4.4e-177 yhbB S Putative amidase domain
NKCFMEJF_01274 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NKCFMEJF_01275 1.2e-109 yhbD K Protein of unknown function (DUF4004)
NKCFMEJF_01276 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NKCFMEJF_01277 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NKCFMEJF_01278 0.0 prkA T Ser protein kinase
NKCFMEJF_01279 2.5e-225 yhbH S Belongs to the UPF0229 family
NKCFMEJF_01280 2.2e-76 yhbI K DNA-binding transcription factor activity
NKCFMEJF_01281 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NKCFMEJF_01282 3.1e-271 yhcA EGP Major facilitator Superfamily
NKCFMEJF_01283 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NKCFMEJF_01284 2.8e-37 yhcC
NKCFMEJF_01285 7.8e-55
NKCFMEJF_01286 7.8e-42 yhcF K Transcriptional regulator
NKCFMEJF_01287 1.6e-123 yhcG V ABC transporter, ATP-binding protein
NKCFMEJF_01288 2.6e-166 yhcH V ABC transporter, ATP-binding protein
NKCFMEJF_01289 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NKCFMEJF_01290 1e-30 cspB K Cold-shock protein
NKCFMEJF_01291 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
NKCFMEJF_01292 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NKCFMEJF_01293 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKCFMEJF_01294 3.7e-44 yhcM
NKCFMEJF_01295 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKCFMEJF_01296 2.5e-167 yhcP
NKCFMEJF_01297 5.2e-100 yhcQ M Spore coat protein
NKCFMEJF_01298 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NKCFMEJF_01299 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NKCFMEJF_01300 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NKCFMEJF_01301 9.3e-68 yhcU S Family of unknown function (DUF5365)
NKCFMEJF_01302 9.9e-68 yhcV S COG0517 FOG CBS domain
NKCFMEJF_01303 4.6e-120 yhcW 5.4.2.6 S hydrolase
NKCFMEJF_01304 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NKCFMEJF_01305 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKCFMEJF_01306 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NKCFMEJF_01307 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NKCFMEJF_01308 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NKCFMEJF_01309 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NKCFMEJF_01310 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NKCFMEJF_01311 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
NKCFMEJF_01312 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKCFMEJF_01313 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
NKCFMEJF_01314 1.2e-38 yhdB S YhdB-like protein
NKCFMEJF_01315 4.8e-54 yhdC S Protein of unknown function (DUF3889)
NKCFMEJF_01316 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NKCFMEJF_01317 3.5e-76 nsrR K Transcriptional regulator
NKCFMEJF_01318 8.7e-239 ygxB M Conserved TM helix
NKCFMEJF_01319 2.1e-276 ycgB S Stage V sporulation protein R
NKCFMEJF_01320 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NKCFMEJF_01321 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NKCFMEJF_01322 3.8e-162 citR K Transcriptional regulator
NKCFMEJF_01323 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
NKCFMEJF_01324 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKCFMEJF_01325 3.4e-250 yhdG E amino acid
NKCFMEJF_01326 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NKCFMEJF_01327 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKCFMEJF_01328 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKCFMEJF_01329 8.1e-45 yhdK S Sigma-M inhibitor protein
NKCFMEJF_01330 6.6e-201 yhdL S Sigma factor regulator N-terminal
NKCFMEJF_01331 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NKCFMEJF_01332 1.5e-191 yhdN C Aldo keto reductase
NKCFMEJF_01333 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NKCFMEJF_01334 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NKCFMEJF_01335 4.1e-74 cueR K transcriptional
NKCFMEJF_01336 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
NKCFMEJF_01337 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NKCFMEJF_01338 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NKCFMEJF_01339 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NKCFMEJF_01340 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NKCFMEJF_01342 6.6e-204 yhdY M Mechanosensitive ion channel
NKCFMEJF_01343 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NKCFMEJF_01344 1.7e-151 yheN G deacetylase
NKCFMEJF_01345 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NKCFMEJF_01346 2.2e-233 nhaC C Na H antiporter
NKCFMEJF_01347 3.4e-84 nhaX T Belongs to the universal stress protein A family
NKCFMEJF_01348 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NKCFMEJF_01349 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NKCFMEJF_01350 3.7e-111 yheG GM NAD(P)H-binding
NKCFMEJF_01351 6.3e-28 sspB S spore protein
NKCFMEJF_01352 1.3e-36 yheE S Family of unknown function (DUF5342)
NKCFMEJF_01353 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NKCFMEJF_01354 4.3e-216 yheC HJ YheC/D like ATP-grasp
NKCFMEJF_01355 6.7e-204 yheB S Belongs to the UPF0754 family
NKCFMEJF_01356 9.5e-48 yheA S Belongs to the UPF0342 family
NKCFMEJF_01357 3.1e-206 yhaZ L DNA alkylation repair enzyme
NKCFMEJF_01358 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NKCFMEJF_01359 7.1e-294 hemZ H coproporphyrinogen III oxidase
NKCFMEJF_01360 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NKCFMEJF_01361 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NKCFMEJF_01363 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
NKCFMEJF_01364 1.1e-26 S YhzD-like protein
NKCFMEJF_01365 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
NKCFMEJF_01366 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NKCFMEJF_01367 3.6e-227 yhaO L DNA repair exonuclease
NKCFMEJF_01368 0.0 yhaN L AAA domain
NKCFMEJF_01369 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NKCFMEJF_01370 1.6e-21 yhaL S Sporulation protein YhaL
NKCFMEJF_01371 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NKCFMEJF_01372 8.7e-90 yhaK S Putative zincin peptidase
NKCFMEJF_01373 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NKCFMEJF_01374 1e-113 hpr K Negative regulator of protease production and sporulation
NKCFMEJF_01375 7e-39 yhaH S YtxH-like protein
NKCFMEJF_01376 3.6e-80 trpP S Tryptophan transporter TrpP
NKCFMEJF_01377 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NKCFMEJF_01378 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NKCFMEJF_01379 4.6e-137 ecsA V transporter (ATP-binding protein)
NKCFMEJF_01380 1.8e-215 ecsB U ABC transporter
NKCFMEJF_01381 4.8e-115 ecsC S EcsC protein family
NKCFMEJF_01382 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NKCFMEJF_01383 4.2e-248 yhfA C membrane
NKCFMEJF_01384 5.4e-10 1.15.1.2 C Rubrerythrin
NKCFMEJF_01385 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NKCFMEJF_01386 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NKCFMEJF_01387 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NKCFMEJF_01388 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NKCFMEJF_01389 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NKCFMEJF_01390 1.4e-101 yhgD K Transcriptional regulator
NKCFMEJF_01391 1e-238 yhgE S YhgE Pip N-terminal domain protein
NKCFMEJF_01392 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NKCFMEJF_01393 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
NKCFMEJF_01394 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NKCFMEJF_01395 1.7e-72 3.4.13.21 S ASCH
NKCFMEJF_01396 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKCFMEJF_01397 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NKCFMEJF_01398 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
NKCFMEJF_01399 2.6e-112 yhfK GM NmrA-like family
NKCFMEJF_01400 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NKCFMEJF_01401 1.9e-65 yhfM
NKCFMEJF_01402 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
NKCFMEJF_01403 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NKCFMEJF_01404 9.2e-80 VY92_01935 K acetyltransferase
NKCFMEJF_01405 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
NKCFMEJF_01406 4.3e-159 yfmC M Periplasmic binding protein
NKCFMEJF_01407 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NKCFMEJF_01408 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
NKCFMEJF_01409 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NKCFMEJF_01410 5e-91 bioY S BioY family
NKCFMEJF_01411 1.7e-182 hemAT NT chemotaxis protein
NKCFMEJF_01412 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NKCFMEJF_01413 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKCFMEJF_01414 1.3e-32 yhzC S IDEAL
NKCFMEJF_01415 4.2e-109 comK K Competence transcription factor
NKCFMEJF_01416 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
NKCFMEJF_01417 7.8e-42 yhjA S Excalibur calcium-binding domain
NKCFMEJF_01418 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKCFMEJF_01419 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NKCFMEJF_01420 5e-60 yhjD
NKCFMEJF_01421 9.1e-110 yhjE S SNARE associated Golgi protein
NKCFMEJF_01422 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NKCFMEJF_01423 1.1e-286 yhjG CH FAD binding domain
NKCFMEJF_01424 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NKCFMEJF_01425 6.9e-215 glcP G Major Facilitator Superfamily
NKCFMEJF_01426 6.4e-190 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NKCFMEJF_01427 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NKCFMEJF_01428 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NKCFMEJF_01429 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
NKCFMEJF_01430 3.8e-202 abrB S membrane
NKCFMEJF_01431 3.1e-215 EGP Transmembrane secretion effector
NKCFMEJF_01432 0.0 S Sugar transport-related sRNA regulator N-term
NKCFMEJF_01433 2e-36 yhjQ C COG1145 Ferredoxin
NKCFMEJF_01434 2.2e-78 yhjR S Rubrerythrin
NKCFMEJF_01435 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NKCFMEJF_01436 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NKCFMEJF_01437 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NKCFMEJF_01438 0.0 sbcC L COG0419 ATPase involved in DNA repair
NKCFMEJF_01439 6e-51 yisB V COG1403 Restriction endonuclease
NKCFMEJF_01440 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NKCFMEJF_01441 3e-66 gerPE S Spore germination protein GerPE
NKCFMEJF_01442 6.3e-24 gerPD S Spore germination protein
NKCFMEJF_01443 1.8e-54 gerPC S Spore germination protein
NKCFMEJF_01444 4e-34 gerPB S cell differentiation
NKCFMEJF_01445 1.9e-33 gerPA S Spore germination protein
NKCFMEJF_01446 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NKCFMEJF_01447 1.7e-176 cotH M Spore Coat
NKCFMEJF_01448 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NKCFMEJF_01449 3e-57 yisL S UPF0344 protein
NKCFMEJF_01450 0.0 wprA O Belongs to the peptidase S8 family
NKCFMEJF_01451 7.2e-106 yisN S Protein of unknown function (DUF2777)
NKCFMEJF_01452 0.0 asnO 6.3.5.4 E Asparagine synthase
NKCFMEJF_01453 2.1e-88 yizA S Damage-inducible protein DinB
NKCFMEJF_01454 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NKCFMEJF_01455 4e-243 yisQ V Mate efflux family protein
NKCFMEJF_01456 1.4e-161 yisR K Transcriptional regulator
NKCFMEJF_01457 2.4e-184 purR K helix_turn _helix lactose operon repressor
NKCFMEJF_01458 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NKCFMEJF_01459 1.3e-93 yisT S DinB family
NKCFMEJF_01460 6.4e-108 argO S Lysine exporter protein LysE YggA
NKCFMEJF_01461 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKCFMEJF_01462 4e-36 mcbG S Pentapeptide repeats (9 copies)
NKCFMEJF_01463 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NKCFMEJF_01464 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NKCFMEJF_01465 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NKCFMEJF_01466 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NKCFMEJF_01467 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
NKCFMEJF_01468 1.9e-141 yitD 4.4.1.19 S synthase
NKCFMEJF_01469 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NKCFMEJF_01470 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NKCFMEJF_01471 4e-229 yitG EGP Major facilitator Superfamily
NKCFMEJF_01472 1.8e-161 yitH K Acetyltransferase (GNAT) domain
NKCFMEJF_01473 2e-82 yjcF S Acetyltransferase (GNAT) domain
NKCFMEJF_01474 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NKCFMEJF_01475 8.6e-55 yajQ S Belongs to the UPF0234 family
NKCFMEJF_01476 1.5e-160 cvfB S protein conserved in bacteria
NKCFMEJF_01477 8.5e-94
NKCFMEJF_01478 2.8e-171
NKCFMEJF_01479 1.5e-97 S Sporulation delaying protein SdpA
NKCFMEJF_01480 1.5e-58 K Transcriptional regulator PadR-like family
NKCFMEJF_01481 2e-95
NKCFMEJF_01482 1.4e-44 yitR S Domain of unknown function (DUF3784)
NKCFMEJF_01483 2.2e-311 nprB 3.4.24.28 E Peptidase M4
NKCFMEJF_01484 8.4e-159 yitS S protein conserved in bacteria
NKCFMEJF_01485 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NKCFMEJF_01486 1.9e-72 ipi S Intracellular proteinase inhibitor
NKCFMEJF_01487 1.2e-17 S Protein of unknown function (DUF3813)
NKCFMEJF_01488 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NKCFMEJF_01489 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NKCFMEJF_01490 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NKCFMEJF_01491 1.5e-22 pilT S Proteolipid membrane potential modulator
NKCFMEJF_01492 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
NKCFMEJF_01493 1.7e-88 norB G Major Facilitator Superfamily
NKCFMEJF_01494 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NKCFMEJF_01495 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NKCFMEJF_01496 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NKCFMEJF_01497 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NKCFMEJF_01498 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NKCFMEJF_01499 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NKCFMEJF_01500 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NKCFMEJF_01501 9.5e-28 yjzC S YjzC-like protein
NKCFMEJF_01502 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NKCFMEJF_01503 6.2e-142 yjaU I carboxylic ester hydrolase activity
NKCFMEJF_01504 7.3e-103 yjaV
NKCFMEJF_01505 1.1e-183 med S Transcriptional activator protein med
NKCFMEJF_01506 7.3e-26 comZ S ComZ
NKCFMEJF_01507 2.7e-22 yjzB
NKCFMEJF_01508 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NKCFMEJF_01509 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NKCFMEJF_01510 7.8e-151 yjaZ O Zn-dependent protease
NKCFMEJF_01511 1.8e-184 appD P Belongs to the ABC transporter superfamily
NKCFMEJF_01512 6.5e-187 appF E Belongs to the ABC transporter superfamily
NKCFMEJF_01513 3.5e-48 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NKCFMEJF_01514 1.9e-190 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NKCFMEJF_01515 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKCFMEJF_01516 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKCFMEJF_01517 5e-147 yjbA S Belongs to the UPF0736 family
NKCFMEJF_01518 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NKCFMEJF_01519 0.0 oppA E ABC transporter substrate-binding protein
NKCFMEJF_01520 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKCFMEJF_01521 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKCFMEJF_01522 3e-198 oppD P Belongs to the ABC transporter superfamily
NKCFMEJF_01523 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NKCFMEJF_01524 8.6e-196 yjbB EGP Major Facilitator Superfamily
NKCFMEJF_01525 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKCFMEJF_01526 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NKCFMEJF_01527 6e-112 yjbE P Integral membrane protein TerC family
NKCFMEJF_01528 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NKCFMEJF_01529 2.3e-223 yjbF S Competence protein
NKCFMEJF_01530 0.0 pepF E oligoendopeptidase F
NKCFMEJF_01531 1.8e-20
NKCFMEJF_01533 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NKCFMEJF_01534 3.7e-72 yjbI S Bacterial-like globin
NKCFMEJF_01535 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NKCFMEJF_01536 2.4e-101 yjbK S protein conserved in bacteria
NKCFMEJF_01537 7.1e-62 yjbL S Belongs to the UPF0738 family
NKCFMEJF_01538 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NKCFMEJF_01539 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NKCFMEJF_01540 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NKCFMEJF_01541 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NKCFMEJF_01542 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NKCFMEJF_01543 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NKCFMEJF_01544 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NKCFMEJF_01545 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
NKCFMEJF_01546 3e-30 thiS H thiamine diphosphate biosynthetic process
NKCFMEJF_01547 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NKCFMEJF_01548 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NKCFMEJF_01549 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NKCFMEJF_01550 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NKCFMEJF_01551 5.9e-54 yjbX S Spore coat protein
NKCFMEJF_01552 5.2e-83 cotZ S Spore coat protein
NKCFMEJF_01553 3.4e-96 cotY S Spore coat protein Z
NKCFMEJF_01554 6.4e-77 cotX S Spore Coat Protein X and V domain
NKCFMEJF_01555 3e-32 cotW
NKCFMEJF_01556 2.3e-55 cotV S Spore Coat Protein X and V domain
NKCFMEJF_01557 8.7e-57 yjcA S Protein of unknown function (DUF1360)
NKCFMEJF_01560 2.9e-38 spoVIF S Stage VI sporulation protein F
NKCFMEJF_01561 0.0 yjcD 3.6.4.12 L DNA helicase
NKCFMEJF_01562 1.7e-38
NKCFMEJF_01563 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKCFMEJF_01564 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NKCFMEJF_01565 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
NKCFMEJF_01566 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NKCFMEJF_01567 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NKCFMEJF_01568 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
NKCFMEJF_01569 1.1e-212 yjcL S Protein of unknown function (DUF819)
NKCFMEJF_01572 2.1e-190 S Putative amidase domain
NKCFMEJF_01573 2.6e-44 yjcN
NKCFMEJF_01576 8.5e-81 L Transposase
NKCFMEJF_01577 1.6e-72 yjcP
NKCFMEJF_01578 4.1e-49 S YjcQ protein
NKCFMEJF_01579 1.1e-92 yqaS L DNA packaging
NKCFMEJF_01580 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
NKCFMEJF_01581 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
NKCFMEJF_01583 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NKCFMEJF_01584 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NKCFMEJF_01585 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NKCFMEJF_01586 4.8e-51 yjdF S Protein of unknown function (DUF2992)
NKCFMEJF_01587 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NKCFMEJF_01589 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NKCFMEJF_01590 4.2e-29 S Domain of unknown function (DUF4177)
NKCFMEJF_01591 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
NKCFMEJF_01592 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NKCFMEJF_01594 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
NKCFMEJF_01595 5.5e-83 S Protein of unknown function (DUF2690)
NKCFMEJF_01596 3.6e-21 yjfB S Putative motility protein
NKCFMEJF_01597 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
NKCFMEJF_01598 1.2e-45 T PhoQ Sensor
NKCFMEJF_01599 8.9e-104 yjgB S Domain of unknown function (DUF4309)
NKCFMEJF_01600 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NKCFMEJF_01601 4.3e-95 yjgD S Protein of unknown function (DUF1641)
NKCFMEJF_01602 8.7e-07 S Domain of unknown function (DUF4352)
NKCFMEJF_01603 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NKCFMEJF_01605 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NKCFMEJF_01606 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NKCFMEJF_01607 8.2e-30
NKCFMEJF_01608 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NKCFMEJF_01609 1.9e-122 ybbM S transport system, permease component
NKCFMEJF_01610 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NKCFMEJF_01611 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
NKCFMEJF_01612 2.8e-93 yjlB S Cupin domain
NKCFMEJF_01613 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NKCFMEJF_01614 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NKCFMEJF_01615 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
NKCFMEJF_01616 5.8e-250 yjmB G symporter YjmB
NKCFMEJF_01617 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NKCFMEJF_01618 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NKCFMEJF_01619 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NKCFMEJF_01620 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_01621 3.7e-227 exuT G Sugar (and other) transporter
NKCFMEJF_01622 2.3e-184 exuR K transcriptional
NKCFMEJF_01623 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NKCFMEJF_01624 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NKCFMEJF_01625 4.3e-130 MA20_18170 S membrane transporter protein
NKCFMEJF_01626 3.3e-80 yjoA S DinB family
NKCFMEJF_01627 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NKCFMEJF_01628 2.1e-213 S response regulator aspartate phosphatase
NKCFMEJF_01630 6.3e-41 S YCII-related domain
NKCFMEJF_01631 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NKCFMEJF_01632 2.1e-61 yjqA S Bacterial PH domain
NKCFMEJF_01633 4.2e-112 yjqB S Pfam:DUF867
NKCFMEJF_01634 4.4e-160 ydbD P Catalase
NKCFMEJF_01635 1.6e-111 xkdA E IrrE N-terminal-like domain
NKCFMEJF_01636 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NKCFMEJF_01638 5.9e-157 xkdB K sequence-specific DNA binding
NKCFMEJF_01639 6.4e-119 xkdC L Bacterial dnaA protein
NKCFMEJF_01642 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NKCFMEJF_01643 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NKCFMEJF_01644 4.8e-140 xtmA L phage terminase small subunit
NKCFMEJF_01645 9.6e-255 xtmB S phage terminase, large subunit
NKCFMEJF_01646 5.4e-286 yqbA S portal protein
NKCFMEJF_01647 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NKCFMEJF_01648 5.8e-169 xkdG S Phage capsid family
NKCFMEJF_01649 5.5e-65 yqbG S Protein of unknown function (DUF3199)
NKCFMEJF_01650 8.7e-65 yqbH S Domain of unknown function (DUF3599)
NKCFMEJF_01651 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
NKCFMEJF_01652 1.9e-77 xkdJ
NKCFMEJF_01653 2.5e-256 xkdK S Phage tail sheath C-terminal domain
NKCFMEJF_01654 6.1e-76 xkdM S Phage tail tube protein
NKCFMEJF_01655 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
NKCFMEJF_01656 0.0 xkdO L Transglycosylase SLT domain
NKCFMEJF_01657 3.7e-122 xkdP S Lysin motif
NKCFMEJF_01658 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NKCFMEJF_01659 2.1e-39 xkdR S Protein of unknown function (DUF2577)
NKCFMEJF_01660 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NKCFMEJF_01661 1.2e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NKCFMEJF_01662 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NKCFMEJF_01663 6.7e-41
NKCFMEJF_01664 0.0
NKCFMEJF_01665 2.6e-55 xkdW S XkdW protein
NKCFMEJF_01666 1.7e-23 xkdX
NKCFMEJF_01667 1.2e-154 xepA
NKCFMEJF_01668 2.8e-39 xhlA S Haemolysin XhlA
NKCFMEJF_01669 9.3e-40 xhlB S SPP1 phage holin
NKCFMEJF_01670 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NKCFMEJF_01671 6.7e-23 spoIISB S Stage II sporulation protein SB
NKCFMEJF_01672 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NKCFMEJF_01673 5.8e-175 pit P phosphate transporter
NKCFMEJF_01674 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NKCFMEJF_01675 9.4e-242 steT E amino acid
NKCFMEJF_01676 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NKCFMEJF_01678 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NKCFMEJF_01679 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NKCFMEJF_01681 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKCFMEJF_01682 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NKCFMEJF_01683 7.9e-154 dppA E D-aminopeptidase
NKCFMEJF_01684 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKCFMEJF_01685 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NKCFMEJF_01686 3.4e-191 dppD P Belongs to the ABC transporter superfamily
NKCFMEJF_01687 0.0 dppE E ABC transporter substrate-binding protein
NKCFMEJF_01689 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NKCFMEJF_01690 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NKCFMEJF_01691 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NKCFMEJF_01692 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
NKCFMEJF_01693 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
NKCFMEJF_01694 5.3e-161 ykgA E Amidinotransferase
NKCFMEJF_01695 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NKCFMEJF_01696 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NKCFMEJF_01697 1e-07
NKCFMEJF_01698 6.3e-120 ykjA S Protein of unknown function (DUF421)
NKCFMEJF_01699 1e-98 ykkA S Protein of unknown function (DUF664)
NKCFMEJF_01700 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NKCFMEJF_01701 3.5e-55 ykkC P Multidrug resistance protein
NKCFMEJF_01702 1.1e-50 ykkD P Multidrug resistance protein
NKCFMEJF_01703 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NKCFMEJF_01704 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NKCFMEJF_01705 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NKCFMEJF_01706 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NKCFMEJF_01707 3.9e-75 ohrR K COG1846 Transcriptional regulators
NKCFMEJF_01708 8.4e-72 ohrB O Organic hydroperoxide resistance protein
NKCFMEJF_01710 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NKCFMEJF_01711 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NKCFMEJF_01712 1.7e-176 isp O Belongs to the peptidase S8 family
NKCFMEJF_01713 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKCFMEJF_01714 1.8e-136 ykoC P Cobalt transport protein
NKCFMEJF_01715 4.6e-311 P ABC transporter, ATP-binding protein
NKCFMEJF_01716 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
NKCFMEJF_01717 7.9e-111 ykoF S YKOF-related Family
NKCFMEJF_01718 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_01719 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
NKCFMEJF_01720 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
NKCFMEJF_01721 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
NKCFMEJF_01724 2.2e-222 mgtE P Acts as a magnesium transporter
NKCFMEJF_01725 1.4e-53 tnrA K transcriptional
NKCFMEJF_01726 5.9e-18
NKCFMEJF_01727 6.9e-26 ykoL
NKCFMEJF_01728 3.7e-61 mhqR K transcriptional
NKCFMEJF_01729 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NKCFMEJF_01730 3.7e-99 ykoP G polysaccharide deacetylase
NKCFMEJF_01731 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NKCFMEJF_01732 0.0 ykoS
NKCFMEJF_01733 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NKCFMEJF_01734 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NKCFMEJF_01735 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NKCFMEJF_01736 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NKCFMEJF_01737 1.4e-116 ykoX S membrane-associated protein
NKCFMEJF_01738 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NKCFMEJF_01739 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKCFMEJF_01740 8.2e-117 rsgI S Anti-sigma factor N-terminus
NKCFMEJF_01741 1.9e-26 sspD S small acid-soluble spore protein
NKCFMEJF_01742 1.5e-124 ykrK S Domain of unknown function (DUF1836)
NKCFMEJF_01743 7e-156 htpX O Belongs to the peptidase M48B family
NKCFMEJF_01744 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NKCFMEJF_01745 1.2e-10 ydfR S Protein of unknown function (DUF421)
NKCFMEJF_01746 4.5e-22 ykzE
NKCFMEJF_01747 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NKCFMEJF_01748 0.0 kinE 2.7.13.3 T Histidine kinase
NKCFMEJF_01749 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NKCFMEJF_01751 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NKCFMEJF_01752 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NKCFMEJF_01753 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NKCFMEJF_01754 8e-232 mtnE 2.6.1.83 E Aminotransferase
NKCFMEJF_01755 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NKCFMEJF_01756 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NKCFMEJF_01757 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NKCFMEJF_01758 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NKCFMEJF_01759 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
NKCFMEJF_01760 6.4e-09 S Spo0E like sporulation regulatory protein
NKCFMEJF_01761 1.4e-64 eag
NKCFMEJF_01762 2.1e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NKCFMEJF_01763 1.3e-75 ykvE K transcriptional
NKCFMEJF_01764 2.5e-125 motB N Flagellar motor protein
NKCFMEJF_01765 2.7e-138 motA N flagellar motor
NKCFMEJF_01766 0.0 clpE O Belongs to the ClpA ClpB family
NKCFMEJF_01767 8.7e-182 ykvI S membrane
NKCFMEJF_01768 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NKCFMEJF_01769 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NKCFMEJF_01770 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NKCFMEJF_01771 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NKCFMEJF_01772 7.6e-61 ykvN K Transcriptional regulator
NKCFMEJF_01773 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
NKCFMEJF_01774 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
NKCFMEJF_01775 1.2e-35 3.5.1.104 M LysM domain
NKCFMEJF_01776 8.5e-133 G Glycosyl hydrolases family 18
NKCFMEJF_01777 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NKCFMEJF_01778 6e-25 ykvS S protein conserved in bacteria
NKCFMEJF_01779 2.8e-28
NKCFMEJF_01780 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NKCFMEJF_01781 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKCFMEJF_01782 4.9e-90 stoA CO thiol-disulfide
NKCFMEJF_01783 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NKCFMEJF_01784 3.8e-09
NKCFMEJF_01785 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NKCFMEJF_01787 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
NKCFMEJF_01789 4.5e-128 glcT K antiterminator
NKCFMEJF_01790 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKCFMEJF_01791 2.1e-39 ptsH G phosphocarrier protein HPr
NKCFMEJF_01792 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NKCFMEJF_01793 7.2e-39 splA S Transcriptional regulator
NKCFMEJF_01794 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
NKCFMEJF_01795 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKCFMEJF_01796 2e-264 mcpC NT chemotaxis protein
NKCFMEJF_01797 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NKCFMEJF_01798 8e-124 ykwD J protein with SCP PR1 domains
NKCFMEJF_01799 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NKCFMEJF_01800 0.0 pilS 2.7.13.3 T Histidine kinase
NKCFMEJF_01801 8e-224 patA 2.6.1.1 E Aminotransferase
NKCFMEJF_01802 2.2e-15
NKCFMEJF_01803 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NKCFMEJF_01804 1.7e-84 ykyB S YkyB-like protein
NKCFMEJF_01805 1.6e-238 ykuC EGP Major facilitator Superfamily
NKCFMEJF_01806 4.6e-88 ykuD S protein conserved in bacteria
NKCFMEJF_01807 9.4e-166 ykuE S Metallophosphoesterase
NKCFMEJF_01808 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKCFMEJF_01809 0.0 3.2.1.132 M Putative peptidoglycan binding domain
NKCFMEJF_01810 1.7e-93 M Peptidoglycan-binding domain 1 protein
NKCFMEJF_01812 5.2e-234 ykuI T Diguanylate phosphodiesterase
NKCFMEJF_01813 3.9e-37 ykuJ S protein conserved in bacteria
NKCFMEJF_01814 4.4e-94 ykuK S Ribonuclease H-like
NKCFMEJF_01815 3.9e-27 ykzF S Antirepressor AbbA
NKCFMEJF_01816 1.6e-76 ykuL S CBS domain
NKCFMEJF_01817 3.5e-168 ccpC K Transcriptional regulator
NKCFMEJF_01818 5.7e-88 fld C Flavodoxin domain
NKCFMEJF_01819 3.2e-177 ykuO
NKCFMEJF_01820 3.2e-80 fld C Flavodoxin
NKCFMEJF_01821 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NKCFMEJF_01822 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NKCFMEJF_01823 9e-37 ykuS S Belongs to the UPF0180 family
NKCFMEJF_01824 8.8e-142 ykuT M Mechanosensitive ion channel
NKCFMEJF_01825 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NKCFMEJF_01826 4.4e-82 ykuV CO thiol-disulfide
NKCFMEJF_01827 5.8e-95 rok K Repressor of ComK
NKCFMEJF_01828 2.9e-147 yknT
NKCFMEJF_01829 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NKCFMEJF_01830 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NKCFMEJF_01831 8.1e-246 moeA 2.10.1.1 H molybdopterin
NKCFMEJF_01832 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NKCFMEJF_01833 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NKCFMEJF_01834 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NKCFMEJF_01835 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NKCFMEJF_01836 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NKCFMEJF_01837 1e-117 yknW S Yip1 domain
NKCFMEJF_01838 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NKCFMEJF_01839 2.5e-124 macB V ABC transporter, ATP-binding protein
NKCFMEJF_01840 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NKCFMEJF_01841 3.1e-136 fruR K Transcriptional regulator
NKCFMEJF_01842 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NKCFMEJF_01843 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NKCFMEJF_01844 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NKCFMEJF_01845 8.1e-39 ykoA
NKCFMEJF_01846 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NKCFMEJF_01847 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NKCFMEJF_01848 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NKCFMEJF_01849 1.1e-12 S Uncharacterized protein YkpC
NKCFMEJF_01850 7.7e-183 mreB D Rod-share determining protein MreBH
NKCFMEJF_01851 1.5e-43 abrB K of stationary sporulation gene expression
NKCFMEJF_01852 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NKCFMEJF_01853 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NKCFMEJF_01854 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NKCFMEJF_01855 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NKCFMEJF_01856 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NKCFMEJF_01857 8.2e-31 ykzG S Belongs to the UPF0356 family
NKCFMEJF_01858 1.4e-147 ykrA S hydrolases of the HAD superfamily
NKCFMEJF_01859 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NKCFMEJF_01861 2e-115 recN L Putative cell-wall binding lipoprotein
NKCFMEJF_01862 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NKCFMEJF_01863 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NKCFMEJF_01864 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NKCFMEJF_01865 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NKCFMEJF_01866 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NKCFMEJF_01867 3.5e-277 speA 4.1.1.19 E Arginine
NKCFMEJF_01868 1.6e-42 yktA S Belongs to the UPF0223 family
NKCFMEJF_01869 7.1e-118 yktB S Belongs to the UPF0637 family
NKCFMEJF_01870 7.1e-26 ykzI
NKCFMEJF_01871 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
NKCFMEJF_01872 6.9e-78 ykzC S Acetyltransferase (GNAT) family
NKCFMEJF_01873 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NKCFMEJF_01874 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NKCFMEJF_01875 0.0 ylaA
NKCFMEJF_01876 2.7e-42 ylaB
NKCFMEJF_01877 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NKCFMEJF_01878 1.2e-11 sigC S Putative zinc-finger
NKCFMEJF_01879 1.8e-38 ylaE
NKCFMEJF_01880 8.2e-22 S Family of unknown function (DUF5325)
NKCFMEJF_01881 0.0 typA T GTP-binding protein TypA
NKCFMEJF_01882 4.2e-47 ylaH S YlaH-like protein
NKCFMEJF_01883 2.5e-32 ylaI S protein conserved in bacteria
NKCFMEJF_01884 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKCFMEJF_01885 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NKCFMEJF_01886 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NKCFMEJF_01887 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NKCFMEJF_01888 8.7e-44 ylaN S Belongs to the UPF0358 family
NKCFMEJF_01889 4.5e-214 ftsW D Belongs to the SEDS family
NKCFMEJF_01890 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NKCFMEJF_01891 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NKCFMEJF_01892 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NKCFMEJF_01893 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NKCFMEJF_01894 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NKCFMEJF_01895 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NKCFMEJF_01896 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NKCFMEJF_01897 3e-167 ctaG S cytochrome c oxidase
NKCFMEJF_01898 7e-62 ylbA S YugN-like family
NKCFMEJF_01899 2.6e-74 ylbB T COG0517 FOG CBS domain
NKCFMEJF_01900 3e-201 ylbC S protein with SCP PR1 domains
NKCFMEJF_01901 4.1e-63 ylbD S Putative coat protein
NKCFMEJF_01902 6.7e-37 ylbE S YlbE-like protein
NKCFMEJF_01903 1.8e-75 ylbF S Belongs to the UPF0342 family
NKCFMEJF_01904 7.5e-39 ylbG S UPF0298 protein
NKCFMEJF_01905 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
NKCFMEJF_01906 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NKCFMEJF_01907 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
NKCFMEJF_01908 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
NKCFMEJF_01909 6.8e-187 ylbL T Belongs to the peptidase S16 family
NKCFMEJF_01910 2.8e-235 ylbM S Belongs to the UPF0348 family
NKCFMEJF_01912 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NKCFMEJF_01913 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NKCFMEJF_01914 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NKCFMEJF_01915 4e-89 ylbP K n-acetyltransferase
NKCFMEJF_01916 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NKCFMEJF_01917 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NKCFMEJF_01918 2.9e-78 mraZ K Belongs to the MraZ family
NKCFMEJF_01919 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NKCFMEJF_01920 3.7e-44 ftsL D Essential cell division protein
NKCFMEJF_01921 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NKCFMEJF_01922 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NKCFMEJF_01923 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NKCFMEJF_01924 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NKCFMEJF_01925 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NKCFMEJF_01926 5.7e-186 spoVE D Belongs to the SEDS family
NKCFMEJF_01927 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NKCFMEJF_01928 5.3e-167 murB 1.3.1.98 M cell wall formation
NKCFMEJF_01929 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NKCFMEJF_01930 2.4e-103 ylxW S protein conserved in bacteria
NKCFMEJF_01931 1e-102 ylxX S protein conserved in bacteria
NKCFMEJF_01932 6.2e-58 sbp S small basic protein
NKCFMEJF_01933 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NKCFMEJF_01934 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NKCFMEJF_01935 0.0 bpr O COG1404 Subtilisin-like serine proteases
NKCFMEJF_01936 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NKCFMEJF_01937 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKCFMEJF_01938 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKCFMEJF_01939 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NKCFMEJF_01940 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
NKCFMEJF_01941 2.4e-37 ylmC S sporulation protein
NKCFMEJF_01942 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NKCFMEJF_01943 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NKCFMEJF_01944 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NKCFMEJF_01945 1.3e-39 yggT S membrane
NKCFMEJF_01946 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NKCFMEJF_01947 2.6e-67 divIVA D Cell division initiation protein
NKCFMEJF_01948 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NKCFMEJF_01949 1.3e-63 dksA T COG1734 DnaK suppressor protein
NKCFMEJF_01950 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NKCFMEJF_01951 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NKCFMEJF_01952 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NKCFMEJF_01953 9e-232 pyrP F Xanthine uracil
NKCFMEJF_01954 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NKCFMEJF_01955 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NKCFMEJF_01956 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NKCFMEJF_01957 0.0 carB 6.3.5.5 F Belongs to the CarB family
NKCFMEJF_01958 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NKCFMEJF_01959 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NKCFMEJF_01960 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NKCFMEJF_01961 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NKCFMEJF_01963 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NKCFMEJF_01964 1.1e-179 cysP P phosphate transporter
NKCFMEJF_01965 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NKCFMEJF_01966 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NKCFMEJF_01967 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NKCFMEJF_01968 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NKCFMEJF_01969 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NKCFMEJF_01970 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NKCFMEJF_01971 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NKCFMEJF_01972 2.4e-156 yloC S stress-induced protein
NKCFMEJF_01973 1.5e-40 ylzA S Belongs to the UPF0296 family
NKCFMEJF_01974 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NKCFMEJF_01975 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NKCFMEJF_01976 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NKCFMEJF_01977 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NKCFMEJF_01978 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NKCFMEJF_01979 2.5e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NKCFMEJF_01980 8.4e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NKCFMEJF_01981 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NKCFMEJF_01982 2.4e-141 stp 3.1.3.16 T phosphatase
NKCFMEJF_01983 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NKCFMEJF_01984 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NKCFMEJF_01985 3.5e-91 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NKCFMEJF_01986 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NKCFMEJF_01987 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NKCFMEJF_01988 5.5e-59 asp S protein conserved in bacteria
NKCFMEJF_01989 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
NKCFMEJF_01990 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NKCFMEJF_01991 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NKCFMEJF_01992 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NKCFMEJF_01993 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NKCFMEJF_01994 7.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NKCFMEJF_01995 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NKCFMEJF_01996 4.1e-122 IQ reductase
NKCFMEJF_01997 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NKCFMEJF_01998 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NKCFMEJF_01999 0.0 smc D Required for chromosome condensation and partitioning
NKCFMEJF_02000 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NKCFMEJF_02001 2.9e-87
NKCFMEJF_02002 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NKCFMEJF_02003 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NKCFMEJF_02004 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NKCFMEJF_02005 1.2e-36 ylqC S Belongs to the UPF0109 family
NKCFMEJF_02006 1.3e-61 ylqD S YlqD protein
NKCFMEJF_02007 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NKCFMEJF_02008 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NKCFMEJF_02009 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NKCFMEJF_02010 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NKCFMEJF_02011 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NKCFMEJF_02012 8.5e-291 ylqG
NKCFMEJF_02013 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NKCFMEJF_02014 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NKCFMEJF_02015 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NKCFMEJF_02016 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NKCFMEJF_02017 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NKCFMEJF_02018 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NKCFMEJF_02019 2.5e-169 xerC L tyrosine recombinase XerC
NKCFMEJF_02020 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NKCFMEJF_02021 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NKCFMEJF_02022 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NKCFMEJF_02023 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NKCFMEJF_02024 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
NKCFMEJF_02025 1.9e-31 fliE N Flagellar hook-basal body
NKCFMEJF_02026 2.4e-255 fliF N The M ring may be actively involved in energy transduction
NKCFMEJF_02027 7.4e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NKCFMEJF_02028 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NKCFMEJF_02029 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NKCFMEJF_02030 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NKCFMEJF_02031 7.7e-37 ylxF S MgtE intracellular N domain
NKCFMEJF_02032 1.2e-221 fliK N Flagellar hook-length control protein
NKCFMEJF_02033 1.7e-72 flgD N Flagellar basal body rod modification protein
NKCFMEJF_02034 8.2e-140 flgG N Flagellar basal body rod
NKCFMEJF_02035 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NKCFMEJF_02036 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NKCFMEJF_02037 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NKCFMEJF_02038 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NKCFMEJF_02039 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
NKCFMEJF_02040 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NKCFMEJF_02041 2.2e-36 fliQ N Role in flagellar biosynthesis
NKCFMEJF_02042 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NKCFMEJF_02043 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NKCFMEJF_02044 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NKCFMEJF_02045 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
NKCFMEJF_02046 7.5e-158 flhG D Belongs to the ParA family
NKCFMEJF_02047 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NKCFMEJF_02048 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NKCFMEJF_02049 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NKCFMEJF_02050 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NKCFMEJF_02051 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NKCFMEJF_02052 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKCFMEJF_02053 4.3e-78 ylxL
NKCFMEJF_02054 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NKCFMEJF_02055 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NKCFMEJF_02056 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NKCFMEJF_02057 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NKCFMEJF_02058 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NKCFMEJF_02059 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NKCFMEJF_02060 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NKCFMEJF_02061 7.7e-233 rasP M zinc metalloprotease
NKCFMEJF_02062 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NKCFMEJF_02063 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKCFMEJF_02064 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NKCFMEJF_02065 1.1e-203 nusA K Participates in both transcription termination and antitermination
NKCFMEJF_02066 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NKCFMEJF_02067 3.1e-47 ylxQ J ribosomal protein
NKCFMEJF_02068 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NKCFMEJF_02069 3e-44 ylxP S protein conserved in bacteria
NKCFMEJF_02070 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NKCFMEJF_02071 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NKCFMEJF_02072 3e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NKCFMEJF_02073 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NKCFMEJF_02074 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NKCFMEJF_02075 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NKCFMEJF_02076 4.4e-233 pepR S Belongs to the peptidase M16 family
NKCFMEJF_02077 2.6e-42 ymxH S YlmC YmxH family
NKCFMEJF_02078 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NKCFMEJF_02079 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NKCFMEJF_02080 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NKCFMEJF_02081 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NKCFMEJF_02082 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NKCFMEJF_02083 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NKCFMEJF_02084 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NKCFMEJF_02085 4.4e-32 S YlzJ-like protein
NKCFMEJF_02086 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NKCFMEJF_02087 1.4e-133 ymfC K Transcriptional regulator
NKCFMEJF_02088 1.5e-206 ymfD EGP Major facilitator Superfamily
NKCFMEJF_02089 2.6e-236 ymfF S Peptidase M16
NKCFMEJF_02090 1.4e-242 ymfH S zinc protease
NKCFMEJF_02091 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NKCFMEJF_02092 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NKCFMEJF_02093 2.4e-76 ymfK S Protein of unknown function (DUF3388)
NKCFMEJF_02094 3.1e-53 ymfK S Protein of unknown function (DUF3388)
NKCFMEJF_02095 1.9e-124 ymfM S protein conserved in bacteria
NKCFMEJF_02096 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NKCFMEJF_02097 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
NKCFMEJF_02098 4.4e-43 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NKCFMEJF_02099 4.2e-126 catB 2.3.1.28 V Chloramphenicol acetyltransferase
NKCFMEJF_02100 1.1e-136 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NKCFMEJF_02101 1e-215 pbpX V Beta-lactamase
NKCFMEJF_02102 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NKCFMEJF_02103 1.9e-152 ymdB S protein conserved in bacteria
NKCFMEJF_02104 1.2e-36 spoVS S Stage V sporulation protein S
NKCFMEJF_02105 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NKCFMEJF_02106 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NKCFMEJF_02107 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NKCFMEJF_02108 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NKCFMEJF_02109 2.2e-88 cotE S Spore coat protein
NKCFMEJF_02110 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NKCFMEJF_02111 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NKCFMEJF_02112 2.3e-70 S Regulatory protein YrvL
NKCFMEJF_02114 1.2e-97 ymcC S Membrane
NKCFMEJF_02115 4.4e-109 pksA K Transcriptional regulator
NKCFMEJF_02116 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
NKCFMEJF_02117 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NKCFMEJF_02119 2.4e-186 pksD Q Acyl transferase domain
NKCFMEJF_02120 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NKCFMEJF_02121 1.4e-37 acpK IQ Phosphopantetheine attachment site
NKCFMEJF_02122 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NKCFMEJF_02123 1.3e-245 pksG 2.3.3.10 I synthase
NKCFMEJF_02124 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
NKCFMEJF_02125 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NKCFMEJF_02126 0.0 rhiB IQ polyketide synthase
NKCFMEJF_02127 0.0 pfaA Q Polyketide synthase of type I
NKCFMEJF_02128 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NKCFMEJF_02129 0.0 dhbF IQ polyketide synthase
NKCFMEJF_02130 0.0 pks13 HQ Beta-ketoacyl synthase
NKCFMEJF_02131 2.5e-233 cypA C Cytochrome P450
NKCFMEJF_02132 1.2e-61 ymzB
NKCFMEJF_02133 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
NKCFMEJF_02134 4.6e-252 aprX O Belongs to the peptidase S8 family
NKCFMEJF_02135 2.1e-126 ymaC S Replication protein
NKCFMEJF_02136 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
NKCFMEJF_02137 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NKCFMEJF_02138 4.9e-51 ebrA P Small Multidrug Resistance protein
NKCFMEJF_02140 2.1e-46 ymaF S YmaF family
NKCFMEJF_02141 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NKCFMEJF_02142 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NKCFMEJF_02143 6.3e-23
NKCFMEJF_02144 4.5e-22 ymzA
NKCFMEJF_02145 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NKCFMEJF_02146 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKCFMEJF_02147 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKCFMEJF_02148 2e-109 ymaB
NKCFMEJF_02149 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NKCFMEJF_02150 1.7e-176 spoVK O stage V sporulation protein K
NKCFMEJF_02151 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NKCFMEJF_02152 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NKCFMEJF_02153 1.1e-68 glnR K transcriptional
NKCFMEJF_02154 7e-261 glnA 6.3.1.2 E glutamine synthetase
NKCFMEJF_02155 5e-10
NKCFMEJF_02156 2.5e-32
NKCFMEJF_02157 5.8e-39
NKCFMEJF_02158 6.8e-80 G regulation of fungal-type cell wall biogenesis
NKCFMEJF_02159 4.9e-145 ynaC
NKCFMEJF_02160 2e-99 ynaD J Acetyltransferase (GNAT) domain
NKCFMEJF_02161 1.9e-123 ynaE S Domain of unknown function (DUF3885)
NKCFMEJF_02162 6.4e-60 ynaF
NKCFMEJF_02165 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NKCFMEJF_02166 2.7e-255 xynT G MFS/sugar transport protein
NKCFMEJF_02167 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NKCFMEJF_02168 1e-215 xylR GK ROK family
NKCFMEJF_02169 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NKCFMEJF_02170 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NKCFMEJF_02171 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
NKCFMEJF_02172 3.5e-247 iolT EGP Major facilitator Superfamily
NKCFMEJF_02173 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NKCFMEJF_02174 6.3e-84 yncE S Protein of unknown function (DUF2691)
NKCFMEJF_02175 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NKCFMEJF_02176 5.2e-15
NKCFMEJF_02179 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NKCFMEJF_02181 1.3e-134 S Domain of unknown function, YrpD
NKCFMEJF_02184 7.9e-25 tatA U protein secretion
NKCFMEJF_02185 1.8e-71
NKCFMEJF_02186 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NKCFMEJF_02189 5.7e-286 gerAA EG Spore germination protein
NKCFMEJF_02190 4.5e-197 gerAB U Spore germination
NKCFMEJF_02191 4.2e-220 gerLC S Spore germination protein
NKCFMEJF_02192 7.7e-154 yndG S DoxX-like family
NKCFMEJF_02193 2.6e-117 yndH S Domain of unknown function (DUF4166)
NKCFMEJF_02194 0.0 yndJ S YndJ-like protein
NKCFMEJF_02196 8.6e-139 yndL S Replication protein
NKCFMEJF_02197 5.8e-74 yndM S Protein of unknown function (DUF2512)
NKCFMEJF_02198 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NKCFMEJF_02200 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NKCFMEJF_02201 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NKCFMEJF_02202 9.2e-113 yneB L resolvase
NKCFMEJF_02203 1.3e-32 ynzC S UPF0291 protein
NKCFMEJF_02204 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NKCFMEJF_02205 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NKCFMEJF_02206 1.8e-28 yneF S UPF0154 protein
NKCFMEJF_02207 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NKCFMEJF_02208 7.1e-127 ccdA O cytochrome c biogenesis protein
NKCFMEJF_02209 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NKCFMEJF_02210 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NKCFMEJF_02211 4.2e-74 yneK S Protein of unknown function (DUF2621)
NKCFMEJF_02212 4.1e-65 hspX O Spore coat protein
NKCFMEJF_02213 3.9e-19 sspP S Belongs to the SspP family
NKCFMEJF_02214 2.2e-14 sspO S Belongs to the SspO family
NKCFMEJF_02215 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NKCFMEJF_02216 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NKCFMEJF_02218 3.1e-08 sspN S Small acid-soluble spore protein N family
NKCFMEJF_02219 3.9e-35 tlp S Belongs to the Tlp family
NKCFMEJF_02220 1.2e-73 yneP S Thioesterase-like superfamily
NKCFMEJF_02221 1.3e-53 yneQ
NKCFMEJF_02222 4.1e-49 yneR S Belongs to the HesB IscA family
NKCFMEJF_02223 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NKCFMEJF_02224 6.6e-69 yccU S CoA-binding protein
NKCFMEJF_02225 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NKCFMEJF_02226 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NKCFMEJF_02227 2.3e-12
NKCFMEJF_02228 1.3e-57 ynfC
NKCFMEJF_02229 8.2e-252 agcS E Sodium alanine symporter
NKCFMEJF_02230 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NKCFMEJF_02232 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NKCFMEJF_02233 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NKCFMEJF_02234 2.4e-80 yngA S membrane
NKCFMEJF_02235 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NKCFMEJF_02236 5.5e-104 yngC S membrane-associated protein
NKCFMEJF_02237 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
NKCFMEJF_02238 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NKCFMEJF_02239 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NKCFMEJF_02240 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NKCFMEJF_02241 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NKCFMEJF_02242 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NKCFMEJF_02243 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NKCFMEJF_02244 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NKCFMEJF_02245 1.8e-31 S Family of unknown function (DUF5367)
NKCFMEJF_02246 1.3e-306 yngK T Glycosyl hydrolase-like 10
NKCFMEJF_02247 2.8e-64 yngL S Protein of unknown function (DUF1360)
NKCFMEJF_02248 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NKCFMEJF_02249 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_02250 7.8e-08
NKCFMEJF_02252 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NKCFMEJF_02253 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NKCFMEJF_02254 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NKCFMEJF_02255 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NKCFMEJF_02256 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NKCFMEJF_02257 0.0 ydiF S ABC transporter
NKCFMEJF_02258 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NKCFMEJF_02259 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NKCFMEJF_02260 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NKCFMEJF_02261 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NKCFMEJF_02262 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NKCFMEJF_02263 7.9e-129 ydiL S CAAX protease self-immunity
NKCFMEJF_02264 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NKCFMEJF_02265 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NKCFMEJF_02267 6.4e-66 KL Phage plasmid primase P4 family
NKCFMEJF_02268 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
NKCFMEJF_02269 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NKCFMEJF_02271 1.2e-199 V AAA domain (dynein-related subfamily)
NKCFMEJF_02272 4.9e-257 J LlaJI restriction endonuclease
NKCFMEJF_02273 1.1e-08 ydjC S Abhydrolase domain containing 18
NKCFMEJF_02274 0.0 K NB-ARC domain
NKCFMEJF_02275 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
NKCFMEJF_02276 7.1e-256 gutA G MFS/sugar transport protein
NKCFMEJF_02277 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NKCFMEJF_02278 5.1e-114 pspA KT Phage shock protein A
NKCFMEJF_02279 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NKCFMEJF_02280 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NKCFMEJF_02281 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
NKCFMEJF_02282 4.7e-196 S Ion transport 2 domain protein
NKCFMEJF_02283 2.7e-258 iolT EGP Major facilitator Superfamily
NKCFMEJF_02284 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NKCFMEJF_02285 4.5e-64 ydjM M Lytic transglycolase
NKCFMEJF_02286 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
NKCFMEJF_02288 1.4e-34 ydjO S Cold-inducible protein YdjO
NKCFMEJF_02289 9.5e-160 ydjP I Alpha/beta hydrolase family
NKCFMEJF_02290 2.4e-181 yeaA S Protein of unknown function (DUF4003)
NKCFMEJF_02291 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NKCFMEJF_02292 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NKCFMEJF_02293 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKCFMEJF_02294 1.6e-177 yeaC S COG0714 MoxR-like ATPases
NKCFMEJF_02295 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NKCFMEJF_02296 0.0 yebA E COG1305 Transglutaminase-like enzymes
NKCFMEJF_02297 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NKCFMEJF_02298 6e-212 pbuG S permease
NKCFMEJF_02299 1.1e-118 yebC M Membrane
NKCFMEJF_02301 4e-93 yebE S UPF0316 protein
NKCFMEJF_02302 8e-28 yebG S NETI protein
NKCFMEJF_02303 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NKCFMEJF_02304 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NKCFMEJF_02305 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NKCFMEJF_02306 4.4e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NKCFMEJF_02307 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKCFMEJF_02308 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKCFMEJF_02309 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NKCFMEJF_02310 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NKCFMEJF_02311 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NKCFMEJF_02312 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NKCFMEJF_02313 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NKCFMEJF_02314 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
NKCFMEJF_02315 3.5e-73 K helix_turn_helix ASNC type
NKCFMEJF_02316 2.3e-232 yjeH E Amino acid permease
NKCFMEJF_02317 2.7e-27 S Protein of unknown function (DUF2892)
NKCFMEJF_02318 0.0 yerA 3.5.4.2 F adenine deaminase
NKCFMEJF_02319 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
NKCFMEJF_02320 4.8e-51 yerC S protein conserved in bacteria
NKCFMEJF_02321 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NKCFMEJF_02323 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NKCFMEJF_02324 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NKCFMEJF_02325 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NKCFMEJF_02326 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NKCFMEJF_02327 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
NKCFMEJF_02328 1.6e-123 sapB S MgtC SapB transporter
NKCFMEJF_02329 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKCFMEJF_02330 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKCFMEJF_02331 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NKCFMEJF_02332 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NKCFMEJF_02333 4e-156 yerO K Transcriptional regulator
NKCFMEJF_02334 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NKCFMEJF_02335 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NKCFMEJF_02336 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKCFMEJF_02337 3.2e-98 L Recombinase
NKCFMEJF_02338 3.2e-53 L Resolvase, N terminal domain
NKCFMEJF_02339 0.0 yeeA V Type II restriction enzyme, methylase subunits
NKCFMEJF_02340 0.0 yeeB L DEAD-like helicases superfamily
NKCFMEJF_02341 6.8e-212 pstS P T5orf172
NKCFMEJF_02343 6.2e-31 S Colicin immunity protein / pyocin immunity protein
NKCFMEJF_02344 5.5e-83 S Protein of unknown function, DUF600
NKCFMEJF_02345 0.0 L nucleic acid phosphodiester bond hydrolysis
NKCFMEJF_02346 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
NKCFMEJF_02347 5.5e-214 S Tetratricopeptide repeat
NKCFMEJF_02349 9.4e-127 yeeN K transcriptional regulatory protein
NKCFMEJF_02351 1.2e-103 dhaR3 K Transcriptional regulator
NKCFMEJF_02352 9.7e-82 yesE S SnoaL-like domain
NKCFMEJF_02353 2.2e-159 yesF GM NAD(P)H-binding
NKCFMEJF_02354 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NKCFMEJF_02355 1.5e-45 cotJB S CotJB protein
NKCFMEJF_02356 5.2e-104 cotJC P Spore Coat
NKCFMEJF_02357 4.2e-103 yesJ K Acetyltransferase (GNAT) family
NKCFMEJF_02359 4.4e-104 yesL S Protein of unknown function, DUF624
NKCFMEJF_02360 0.0 yesM 2.7.13.3 T Histidine kinase
NKCFMEJF_02361 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
NKCFMEJF_02362 5e-248 yesO G Bacterial extracellular solute-binding protein
NKCFMEJF_02363 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
NKCFMEJF_02364 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
NKCFMEJF_02365 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NKCFMEJF_02366 0.0 yesS K Transcriptional regulator
NKCFMEJF_02367 3.8e-133 E GDSL-like Lipase/Acylhydrolase
NKCFMEJF_02368 8.9e-132 yesU S Domain of unknown function (DUF1961)
NKCFMEJF_02369 1e-113 yesV S Protein of unknown function, DUF624
NKCFMEJF_02370 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NKCFMEJF_02371 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NKCFMEJF_02372 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
NKCFMEJF_02373 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NKCFMEJF_02374 0.0 yetA
NKCFMEJF_02375 9.6e-291 lplA G Bacterial extracellular solute-binding protein
NKCFMEJF_02376 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NKCFMEJF_02377 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
NKCFMEJF_02378 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NKCFMEJF_02379 6.1e-123 yetF S membrane
NKCFMEJF_02380 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NKCFMEJF_02381 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKCFMEJF_02382 2.2e-34
NKCFMEJF_02383 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKCFMEJF_02384 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKCFMEJF_02385 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NKCFMEJF_02386 5.3e-105 yetJ S Belongs to the BI1 family
NKCFMEJF_02387 5.4e-159 yetK EG EamA-like transporter family
NKCFMEJF_02388 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
NKCFMEJF_02389 7.8e-213 yetM CH FAD binding domain
NKCFMEJF_02390 3.6e-199 yetN S Protein of unknown function (DUF3900)
NKCFMEJF_02391 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NKCFMEJF_02392 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NKCFMEJF_02393 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
NKCFMEJF_02394 1.9e-172 yfnG 4.2.1.45 M dehydratase
NKCFMEJF_02395 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
NKCFMEJF_02396 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NKCFMEJF_02397 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
NKCFMEJF_02398 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
NKCFMEJF_02399 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NKCFMEJF_02400 1.3e-241 yfnA E amino acid
NKCFMEJF_02401 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKCFMEJF_02402 1.1e-113 yfmS NT chemotaxis protein
NKCFMEJF_02403 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NKCFMEJF_02404 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
NKCFMEJF_02405 2.8e-70 yfmP K transcriptional
NKCFMEJF_02406 1.5e-209 yfmO EGP Major facilitator Superfamily
NKCFMEJF_02407 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NKCFMEJF_02408 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NKCFMEJF_02409 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
NKCFMEJF_02410 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
NKCFMEJF_02411 7.7e-214 G Major Facilitator Superfamily
NKCFMEJF_02412 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
NKCFMEJF_02413 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NKCFMEJF_02414 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_02415 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_02416 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NKCFMEJF_02417 2.9e-24 S Protein of unknown function (DUF3212)
NKCFMEJF_02418 7.6e-58 yflT S Heat induced stress protein YflT
NKCFMEJF_02419 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NKCFMEJF_02420 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
NKCFMEJF_02421 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NKCFMEJF_02422 8.9e-119 citT T response regulator
NKCFMEJF_02423 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
NKCFMEJF_02425 8.5e-227 citM C Citrate transporter
NKCFMEJF_02426 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NKCFMEJF_02427 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NKCFMEJF_02428 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NKCFMEJF_02429 9e-124 yflK S protein conserved in bacteria
NKCFMEJF_02430 4e-18 yflJ S Protein of unknown function (DUF2639)
NKCFMEJF_02431 4.1e-19 yflI
NKCFMEJF_02432 2.4e-50 yflH S Protein of unknown function (DUF3243)
NKCFMEJF_02433 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NKCFMEJF_02434 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NKCFMEJF_02435 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NKCFMEJF_02436 6e-67 yhdN S Domain of unknown function (DUF1992)
NKCFMEJF_02437 3.2e-256 agcS_1 E Sodium alanine symporter
NKCFMEJF_02438 1.6e-194 E Spore germination protein
NKCFMEJF_02440 5.1e-207 yfkR S spore germination
NKCFMEJF_02441 1.5e-283 yfkQ EG Spore germination protein
NKCFMEJF_02442 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKCFMEJF_02443 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NKCFMEJF_02444 1.8e-133 treR K transcriptional
NKCFMEJF_02445 1.6e-125 yfkO C nitroreductase
NKCFMEJF_02446 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NKCFMEJF_02447 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
NKCFMEJF_02448 6.8e-207 ydiM EGP Major facilitator Superfamily
NKCFMEJF_02449 2.1e-29 yfkK S Belongs to the UPF0435 family
NKCFMEJF_02450 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NKCFMEJF_02451 8.4e-51 yfkI S gas vesicle protein
NKCFMEJF_02452 9.7e-144 yihY S Belongs to the UPF0761 family
NKCFMEJF_02453 5e-08
NKCFMEJF_02454 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NKCFMEJF_02455 6.1e-183 cax P COG0387 Ca2 H antiporter
NKCFMEJF_02456 1.2e-146 yfkD S YfkD-like protein
NKCFMEJF_02457 6e-149 yfkC M Mechanosensitive ion channel
NKCFMEJF_02458 5.4e-222 yfkA S YfkB-like domain
NKCFMEJF_02459 1.1e-26 yfjT
NKCFMEJF_02460 2.6e-154 pdaA G deacetylase
NKCFMEJF_02461 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NKCFMEJF_02462 1.7e-184 corA P Mediates influx of magnesium ions
NKCFMEJF_02463 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NKCFMEJF_02464 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NKCFMEJF_02465 1.6e-39 S YfzA-like protein
NKCFMEJF_02466 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NKCFMEJF_02467 3.9e-86 yfjM S Psort location Cytoplasmic, score
NKCFMEJF_02468 3e-29 yfjL
NKCFMEJF_02469 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NKCFMEJF_02470 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NKCFMEJF_02471 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NKCFMEJF_02472 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NKCFMEJF_02473 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NKCFMEJF_02474 1.2e-25 sspH S Belongs to the SspH family
NKCFMEJF_02475 4e-56 yfjF S UPF0060 membrane protein
NKCFMEJF_02476 1.3e-80 S Family of unknown function (DUF5381)
NKCFMEJF_02477 1.8e-101 yfjD S Family of unknown function (DUF5381)
NKCFMEJF_02478 4.1e-144 yfjC
NKCFMEJF_02479 9.2e-191 yfjB
NKCFMEJF_02480 1.1e-44 yfjA S Belongs to the WXG100 family
NKCFMEJF_02481 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NKCFMEJF_02482 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
NKCFMEJF_02483 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKCFMEJF_02484 2.1e-310 yfiB3 V ABC transporter
NKCFMEJF_02485 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NKCFMEJF_02486 9.8e-65 mhqP S DoxX
NKCFMEJF_02487 5.7e-163 yfiE 1.13.11.2 S glyoxalase
NKCFMEJF_02488 1.5e-177 K AraC-like ligand binding domain
NKCFMEJF_02489 1.8e-262 iolT EGP Major facilitator Superfamily
NKCFMEJF_02490 4.2e-183 G Xylose isomerase
NKCFMEJF_02491 1.1e-233 S Oxidoreductase
NKCFMEJF_02493 1.1e-214 yxjM T Histidine kinase
NKCFMEJF_02494 3.2e-113 KT LuxR family transcriptional regulator
NKCFMEJF_02495 6.2e-171 V ABC transporter, ATP-binding protein
NKCFMEJF_02496 9.8e-214 V ABC-2 family transporter protein
NKCFMEJF_02497 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
NKCFMEJF_02498 8.3e-99 padR K transcriptional
NKCFMEJF_02499 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NKCFMEJF_02500 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NKCFMEJF_02501 2e-109 yfiR K Transcriptional regulator
NKCFMEJF_02502 5.1e-221 yfiS EGP Major facilitator Superfamily
NKCFMEJF_02503 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
NKCFMEJF_02504 8.7e-287 yfiU EGP Major facilitator Superfamily
NKCFMEJF_02505 3.1e-81 yfiV K transcriptional
NKCFMEJF_02506 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NKCFMEJF_02507 6.2e-182 yfiY P ABC transporter substrate-binding protein
NKCFMEJF_02508 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_02509 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_02510 1.8e-167 yfhB 5.3.3.17 S PhzF family
NKCFMEJF_02511 3.9e-107 yfhC C nitroreductase
NKCFMEJF_02512 2.1e-25 yfhD S YfhD-like protein
NKCFMEJF_02514 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
NKCFMEJF_02515 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NKCFMEJF_02516 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NKCFMEJF_02518 1.1e-209 yfhI EGP Major facilitator Superfamily
NKCFMEJF_02519 6.2e-20 sspK S reproduction
NKCFMEJF_02520 1.3e-44 yfhJ S WVELL protein
NKCFMEJF_02521 9.2e-92 batE T Bacterial SH3 domain homologues
NKCFMEJF_02522 3.5e-51 yfhL S SdpI/YhfL protein family
NKCFMEJF_02523 6.7e-172 yfhM S Alpha beta hydrolase
NKCFMEJF_02524 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NKCFMEJF_02525 0.0 yfhO S Bacterial membrane protein YfhO
NKCFMEJF_02526 5.5e-186 yfhP S membrane-bound metal-dependent
NKCFMEJF_02527 7.8e-212 mutY L A G-specific
NKCFMEJF_02528 6.9e-36 yfhS
NKCFMEJF_02529 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKCFMEJF_02530 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NKCFMEJF_02531 4.9e-48 ygaB S YgaB-like protein
NKCFMEJF_02532 1.3e-104 ygaC J Belongs to the UPF0374 family
NKCFMEJF_02533 1.8e-301 ygaD V ABC transporter
NKCFMEJF_02534 8.7e-180 ygaE S Membrane
NKCFMEJF_02535 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NKCFMEJF_02536 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
NKCFMEJF_02537 4e-80 perR P Belongs to the Fur family
NKCFMEJF_02538 1.5e-56 ygzB S UPF0295 protein
NKCFMEJF_02539 6.7e-167 ygxA S Nucleotidyltransferase-like
NKCFMEJF_02540 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
NKCFMEJF_02541 3.4e-94 M1-753 M FR47-like protein
NKCFMEJF_02542 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
NKCFMEJF_02543 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NKCFMEJF_02544 3.9e-84 yuaE S DinB superfamily
NKCFMEJF_02545 7.9e-108 yuaD
NKCFMEJF_02546 1.1e-29 gbsB 1.1.1.1 C alcohol dehydrogenase
NKCFMEJF_02547 3.7e-185 gbsB 1.1.1.1 C alcohol dehydrogenase
NKCFMEJF_02548 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NKCFMEJF_02549 1.1e-95 yuaC K Belongs to the GbsR family
NKCFMEJF_02550 2.2e-91 yuaB
NKCFMEJF_02551 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
NKCFMEJF_02552 5.4e-237 ktrB P Potassium
NKCFMEJF_02553 1e-38 yiaA S yiaA/B two helix domain
NKCFMEJF_02554 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NKCFMEJF_02555 6.2e-277 yubD P Major Facilitator Superfamily
NKCFMEJF_02556 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NKCFMEJF_02558 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NKCFMEJF_02559 6.3e-197 yubA S transporter activity
NKCFMEJF_02560 3.3e-183 ygjR S Oxidoreductase
NKCFMEJF_02561 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NKCFMEJF_02562 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NKCFMEJF_02563 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NKCFMEJF_02564 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NKCFMEJF_02565 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NKCFMEJF_02566 5.1e-239 mcpA NT chemotaxis protein
NKCFMEJF_02567 2.2e-295 mcpA NT chemotaxis protein
NKCFMEJF_02568 1.5e-222 mcpA NT chemotaxis protein
NKCFMEJF_02569 3.2e-225 mcpA NT chemotaxis protein
NKCFMEJF_02570 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NKCFMEJF_02571 1e-35
NKCFMEJF_02572 2.1e-72 yugU S Uncharacterised protein family UPF0047
NKCFMEJF_02573 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NKCFMEJF_02574 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NKCFMEJF_02575 1.4e-116 yugP S Zn-dependent protease
NKCFMEJF_02576 4.6e-39
NKCFMEJF_02577 1.1e-53 mstX S Membrane-integrating protein Mistic
NKCFMEJF_02578 1.7e-182 yugO P COG1226 Kef-type K transport systems
NKCFMEJF_02579 1.3e-72 yugN S YugN-like family
NKCFMEJF_02581 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NKCFMEJF_02582 2.8e-229 yugK C Dehydrogenase
NKCFMEJF_02583 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NKCFMEJF_02584 1.1e-34 yuzA S Domain of unknown function (DUF378)
NKCFMEJF_02585 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NKCFMEJF_02586 4.3e-200 yugH 2.6.1.1 E Aminotransferase
NKCFMEJF_02587 1.6e-85 alaR K Transcriptional regulator
NKCFMEJF_02588 1e-156 yugF I Hydrolase
NKCFMEJF_02589 9.8e-42 yugE S Domain of unknown function (DUF1871)
NKCFMEJF_02590 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NKCFMEJF_02591 4.6e-233 T PhoQ Sensor
NKCFMEJF_02592 2e-70 kapB G Kinase associated protein B
NKCFMEJF_02593 1.9e-115 kapD L the KinA pathway to sporulation
NKCFMEJF_02595 3.5e-186 yuxJ EGP Major facilitator Superfamily
NKCFMEJF_02596 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NKCFMEJF_02597 6.3e-75 yuxK S protein conserved in bacteria
NKCFMEJF_02598 6e-76 yufK S Family of unknown function (DUF5366)
NKCFMEJF_02599 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NKCFMEJF_02600 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NKCFMEJF_02601 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NKCFMEJF_02602 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NKCFMEJF_02603 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
NKCFMEJF_02604 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
NKCFMEJF_02605 1.3e-233 maeN C COG3493 Na citrate symporter
NKCFMEJF_02606 1.9e-14
NKCFMEJF_02607 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NKCFMEJF_02608 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKCFMEJF_02609 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKCFMEJF_02610 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKCFMEJF_02611 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKCFMEJF_02612 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NKCFMEJF_02613 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NKCFMEJF_02614 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
NKCFMEJF_02615 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKCFMEJF_02616 0.0 comP 2.7.13.3 T Histidine kinase
NKCFMEJF_02618 2.5e-162 comQ H Polyprenyl synthetase
NKCFMEJF_02620 1.1e-22 yuzC
NKCFMEJF_02621 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NKCFMEJF_02622 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NKCFMEJF_02623 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
NKCFMEJF_02624 1.6e-67 yueI S Protein of unknown function (DUF1694)
NKCFMEJF_02625 7.4e-39 yueH S YueH-like protein
NKCFMEJF_02626 2.1e-32 yueG S Spore germination protein gerPA/gerPF
NKCFMEJF_02627 1.9e-190 yueF S transporter activity
NKCFMEJF_02628 6.1e-72 S Protein of unknown function (DUF2283)
NKCFMEJF_02629 2.9e-24 S Protein of unknown function (DUF2642)
NKCFMEJF_02630 4.8e-96 yueE S phosphohydrolase
NKCFMEJF_02631 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKCFMEJF_02632 6.6e-65 yueC S Family of unknown function (DUF5383)
NKCFMEJF_02633 0.0 esaA S type VII secretion protein EsaA
NKCFMEJF_02634 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NKCFMEJF_02635 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NKCFMEJF_02636 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NKCFMEJF_02637 2.8e-45 esxA S Belongs to the WXG100 family
NKCFMEJF_02638 6.5e-229 yukF QT Transcriptional regulator
NKCFMEJF_02639 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NKCFMEJF_02640 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NKCFMEJF_02641 3.8e-36 mbtH S MbtH-like protein
NKCFMEJF_02642 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_02643 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NKCFMEJF_02644 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NKCFMEJF_02645 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
NKCFMEJF_02646 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_02647 1.3e-167 besA S Putative esterase
NKCFMEJF_02648 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NKCFMEJF_02649 1.1e-93 bioY S Biotin biosynthesis protein
NKCFMEJF_02650 3.9e-211 yuiF S antiporter
NKCFMEJF_02651 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NKCFMEJF_02652 1.2e-77 yuiD S protein conserved in bacteria
NKCFMEJF_02653 5.6e-118 yuiC S protein conserved in bacteria
NKCFMEJF_02654 8.4e-27 yuiB S Putative membrane protein
NKCFMEJF_02655 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
NKCFMEJF_02656 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
NKCFMEJF_02658 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NKCFMEJF_02659 9e-118 paiB K Putative FMN-binding domain
NKCFMEJF_02660 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKCFMEJF_02661 3.7e-63 erpA S Belongs to the HesB IscA family
NKCFMEJF_02662 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NKCFMEJF_02663 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NKCFMEJF_02664 3.2e-39 yuzB S Belongs to the UPF0349 family
NKCFMEJF_02665 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NKCFMEJF_02666 3.5e-57 yuzD S protein conserved in bacteria
NKCFMEJF_02667 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NKCFMEJF_02668 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NKCFMEJF_02669 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NKCFMEJF_02670 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NKCFMEJF_02671 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
NKCFMEJF_02672 2e-199 yutH S Spore coat protein
NKCFMEJF_02673 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NKCFMEJF_02674 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NKCFMEJF_02675 1e-75 yutE S Protein of unknown function DUF86
NKCFMEJF_02676 9.7e-48 yutD S protein conserved in bacteria
NKCFMEJF_02677 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NKCFMEJF_02678 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NKCFMEJF_02679 4.5e-196 lytH M Peptidase, M23
NKCFMEJF_02680 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
NKCFMEJF_02681 4.8e-48 yunC S Domain of unknown function (DUF1805)
NKCFMEJF_02682 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NKCFMEJF_02683 2e-141 yunE S membrane transporter protein
NKCFMEJF_02684 4.3e-171 yunF S Protein of unknown function DUF72
NKCFMEJF_02685 3e-62 yunG
NKCFMEJF_02686 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NKCFMEJF_02687 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
NKCFMEJF_02688 2.1e-236 pbuX F Permease family
NKCFMEJF_02689 1.3e-224 pbuX F xanthine
NKCFMEJF_02690 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NKCFMEJF_02691 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NKCFMEJF_02692 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NKCFMEJF_02693 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NKCFMEJF_02694 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NKCFMEJF_02695 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NKCFMEJF_02696 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NKCFMEJF_02698 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NKCFMEJF_02699 7.8e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NKCFMEJF_02700 2.4e-169 bsn L Ribonuclease
NKCFMEJF_02701 1.2e-205 msmX P Belongs to the ABC transporter superfamily
NKCFMEJF_02702 1.2e-134 yurK K UTRA
NKCFMEJF_02703 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NKCFMEJF_02704 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
NKCFMEJF_02705 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
NKCFMEJF_02706 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NKCFMEJF_02707 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NKCFMEJF_02708 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NKCFMEJF_02709 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NKCFMEJF_02711 1e-41
NKCFMEJF_02712 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKCFMEJF_02713 3.5e-271 sufB O FeS cluster assembly
NKCFMEJF_02714 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NKCFMEJF_02715 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NKCFMEJF_02716 1.4e-245 sufD O assembly protein SufD
NKCFMEJF_02717 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NKCFMEJF_02718 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NKCFMEJF_02719 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
NKCFMEJF_02720 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NKCFMEJF_02721 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NKCFMEJF_02722 2.4e-56 yusD S SCP-2 sterol transfer family
NKCFMEJF_02723 5.6e-55 traF CO Thioredoxin
NKCFMEJF_02724 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NKCFMEJF_02725 1.1e-39 yusG S Protein of unknown function (DUF2553)
NKCFMEJF_02726 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NKCFMEJF_02727 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NKCFMEJF_02728 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NKCFMEJF_02729 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NKCFMEJF_02730 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NKCFMEJF_02731 4.7e-09 S YuzL-like protein
NKCFMEJF_02732 2.2e-165 fadM E Proline dehydrogenase
NKCFMEJF_02733 5.1e-40
NKCFMEJF_02734 3.2e-53 yusN M Coat F domain
NKCFMEJF_02735 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
NKCFMEJF_02736 3.8e-293 yusP P Major facilitator superfamily
NKCFMEJF_02737 8.4e-66 yusQ S Tautomerase enzyme
NKCFMEJF_02738 1e-63 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_02739 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_02740 2.7e-160 yusT K LysR substrate binding domain
NKCFMEJF_02741 3.8e-47 yusU S Protein of unknown function (DUF2573)
NKCFMEJF_02742 1e-153 yusV 3.6.3.34 HP ABC transporter
NKCFMEJF_02743 5.6e-66 S YusW-like protein
NKCFMEJF_02744 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
NKCFMEJF_02745 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
NKCFMEJF_02746 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_02747 1.2e-79 dps P Ferritin-like domain
NKCFMEJF_02748 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKCFMEJF_02749 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_02750 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NKCFMEJF_02751 4.3e-158 yuxN K Transcriptional regulator
NKCFMEJF_02752 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NKCFMEJF_02753 2.3e-24 S Protein of unknown function (DUF3970)
NKCFMEJF_02754 2.2e-247 gerAA EG Spore germination protein
NKCFMEJF_02755 9.1e-198 gerAB E Spore germination protein
NKCFMEJF_02756 4.6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
NKCFMEJF_02757 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKCFMEJF_02758 5.5e-187 vraS 2.7.13.3 T Histidine kinase
NKCFMEJF_02759 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NKCFMEJF_02760 9.3e-129 liaG S Putative adhesin
NKCFMEJF_02761 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NKCFMEJF_02762 5.6e-62 liaI S membrane
NKCFMEJF_02763 4.8e-227 yvqJ EGP Major facilitator Superfamily
NKCFMEJF_02764 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
NKCFMEJF_02765 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NKCFMEJF_02766 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_02767 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NKCFMEJF_02768 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_02769 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NKCFMEJF_02770 0.0 T PhoQ Sensor
NKCFMEJF_02771 9.4e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_02772 3.6e-22
NKCFMEJF_02773 1.8e-96 yvrI K RNA polymerase
NKCFMEJF_02774 2.4e-19 S YvrJ protein family
NKCFMEJF_02775 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
NKCFMEJF_02776 1.3e-64 yvrL S Regulatory protein YrvL
NKCFMEJF_02777 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NKCFMEJF_02778 7.1e-124 macB V ABC transporter, ATP-binding protein
NKCFMEJF_02779 4.9e-119 M Efflux transporter rnd family, mfp subunit
NKCFMEJF_02780 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NKCFMEJF_02782 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
NKCFMEJF_02783 2.2e-142 ybbA S Putative esterase
NKCFMEJF_02784 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_02785 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_02786 7.2e-167 feuA P Iron-uptake system-binding protein
NKCFMEJF_02787 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NKCFMEJF_02788 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
NKCFMEJF_02789 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NKCFMEJF_02790 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NKCFMEJF_02791 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKCFMEJF_02792 1.1e-150 ybbH K transcriptional
NKCFMEJF_02793 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NKCFMEJF_02794 6.4e-87 ybbJ J acetyltransferase
NKCFMEJF_02795 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NKCFMEJF_02801 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NKCFMEJF_02802 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NKCFMEJF_02803 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NKCFMEJF_02804 3e-225 ybbR S protein conserved in bacteria
NKCFMEJF_02805 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NKCFMEJF_02806 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NKCFMEJF_02807 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NKCFMEJF_02808 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
NKCFMEJF_02809 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NKCFMEJF_02810 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NKCFMEJF_02811 0.0 ybcC S Belongs to the UPF0753 family
NKCFMEJF_02812 3.7e-96 can 4.2.1.1 P carbonic anhydrase
NKCFMEJF_02813 3.9e-47
NKCFMEJF_02814 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NKCFMEJF_02815 5.1e-50 ybzH K Helix-turn-helix domain
NKCFMEJF_02816 2e-203 ybcL EGP Major facilitator Superfamily
NKCFMEJF_02818 9.1e-239 J 4Fe-4S single cluster domain
NKCFMEJF_02819 1.6e-277 V CAAX protease self-immunity
NKCFMEJF_02820 1.9e-135 skfE V ABC transporter
NKCFMEJF_02821 4e-248 skfF S ABC transporter
NKCFMEJF_02822 7.8e-91 C HEAT repeats
NKCFMEJF_02823 9.6e-79 txn CO Thioredoxin-like
NKCFMEJF_02824 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NKCFMEJF_02825 1.5e-123 T Transcriptional regulatory protein, C terminal
NKCFMEJF_02826 1.8e-173 T His Kinase A (phospho-acceptor) domain
NKCFMEJF_02828 1.6e-140 KLT Protein tyrosine kinase
NKCFMEJF_02829 4.8e-154 ybdN
NKCFMEJF_02830 1.5e-217 ybdO S Domain of unknown function (DUF4885)
NKCFMEJF_02831 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NKCFMEJF_02832 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NKCFMEJF_02833 4.9e-30 ybxH S Family of unknown function (DUF5370)
NKCFMEJF_02834 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
NKCFMEJF_02835 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NKCFMEJF_02836 4.9e-41 ybyB
NKCFMEJF_02837 3e-91 ybeC E amino acid
NKCFMEJF_02838 1.2e-103 ybeC E amino acid
NKCFMEJF_02839 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NKCFMEJF_02840 7.3e-258 glpT G -transporter
NKCFMEJF_02841 2.9e-35 S Protein of unknown function (DUF2651)
NKCFMEJF_02842 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
NKCFMEJF_02843 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
NKCFMEJF_02845 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NKCFMEJF_02846 8.8e-162 ybfH EG EamA-like transporter family
NKCFMEJF_02847 2.3e-145 msmR K AraC-like ligand binding domain
NKCFMEJF_02848 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NKCFMEJF_02849 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NKCFMEJF_02851 2.5e-169 S Alpha/beta hydrolase family
NKCFMEJF_02852 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NKCFMEJF_02853 2.7e-85 ybfM S SNARE associated Golgi protein
NKCFMEJF_02854 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NKCFMEJF_02855 3.2e-46 ybfN
NKCFMEJF_02856 4.3e-258 S Erythromycin esterase
NKCFMEJF_02857 6.7e-167 ybfP K Transcriptional regulator
NKCFMEJF_02858 3.9e-192 yceA S Belongs to the UPF0176 family
NKCFMEJF_02859 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKCFMEJF_02860 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKCFMEJF_02861 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NKCFMEJF_02862 4.9e-128 K UTRA
NKCFMEJF_02864 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NKCFMEJF_02865 6.7e-262 mmuP E amino acid
NKCFMEJF_02866 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NKCFMEJF_02867 2.3e-257 agcS E Sodium alanine symporter
NKCFMEJF_02868 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
NKCFMEJF_02869 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
NKCFMEJF_02870 9e-170 glnL T Regulator
NKCFMEJF_02871 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NKCFMEJF_02872 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKCFMEJF_02873 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NKCFMEJF_02874 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NKCFMEJF_02875 1.5e-124 ycbG K FCD
NKCFMEJF_02876 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
NKCFMEJF_02877 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
NKCFMEJF_02878 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NKCFMEJF_02879 7.3e-172 eamA1 EG spore germination
NKCFMEJF_02880 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_02881 2.4e-170 T PhoQ Sensor
NKCFMEJF_02882 4.8e-168 ycbN V ABC transporter, ATP-binding protein
NKCFMEJF_02883 2.1e-115 S ABC-2 family transporter protein
NKCFMEJF_02884 8.2e-53 ycbP S Protein of unknown function (DUF2512)
NKCFMEJF_02885 1.3e-78 sleB 3.5.1.28 M Cell wall
NKCFMEJF_02886 6.6e-136 ycbR T vWA found in TerF C terminus
NKCFMEJF_02887 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NKCFMEJF_02888 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NKCFMEJF_02889 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NKCFMEJF_02890 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NKCFMEJF_02891 6.2e-210 ycbU E Selenocysteine lyase
NKCFMEJF_02892 5.8e-229 lmrB EGP the major facilitator superfamily
NKCFMEJF_02893 4.8e-102 yxaF K Transcriptional regulator
NKCFMEJF_02894 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NKCFMEJF_02895 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NKCFMEJF_02896 2e-59 S RDD family
NKCFMEJF_02897 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
NKCFMEJF_02898 2e-161 2.7.13.3 T GHKL domain
NKCFMEJF_02899 1.2e-126 lytR_2 T LytTr DNA-binding domain
NKCFMEJF_02900 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NKCFMEJF_02901 4.5e-203 natB CP ABC-2 family transporter protein
NKCFMEJF_02902 1.6e-174 yccK C Aldo keto reductase
NKCFMEJF_02903 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NKCFMEJF_02904 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NKCFMEJF_02905 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NKCFMEJF_02906 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
NKCFMEJF_02907 5.5e-174 S response regulator aspartate phosphatase
NKCFMEJF_02908 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
NKCFMEJF_02909 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NKCFMEJF_02910 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
NKCFMEJF_02911 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NKCFMEJF_02912 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NKCFMEJF_02913 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKCFMEJF_02914 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NKCFMEJF_02915 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NKCFMEJF_02916 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NKCFMEJF_02917 6.3e-137 terC P Protein of unknown function (DUF475)
NKCFMEJF_02918 0.0 yceG S Putative component of 'biosynthetic module'
NKCFMEJF_02919 2e-192 yceH P Belongs to the TelA family
NKCFMEJF_02920 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
NKCFMEJF_02921 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
NKCFMEJF_02922 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NKCFMEJF_02923 5.1e-229 proV 3.6.3.32 E glycine betaine
NKCFMEJF_02924 1.3e-127 opuAB P glycine betaine
NKCFMEJF_02925 5.3e-164 opuAC E glycine betaine
NKCFMEJF_02926 1.2e-219 amhX S amidohydrolase
NKCFMEJF_02927 1e-257 ycgA S Membrane
NKCFMEJF_02928 1.1e-98 ycgB
NKCFMEJF_02929 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NKCFMEJF_02930 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NKCFMEJF_02931 6.5e-293 lctP C L-lactate permease
NKCFMEJF_02932 6.2e-269 mdr EGP Major facilitator Superfamily
NKCFMEJF_02933 7.5e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
NKCFMEJF_02934 6.8e-113 ycgF E Lysine exporter protein LysE YggA
NKCFMEJF_02935 1.2e-151 yqcI S YqcI/YcgG family
NKCFMEJF_02936 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NKCFMEJF_02937 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NKCFMEJF_02938 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NKCFMEJF_02939 2.5e-109 tmrB S AAA domain
NKCFMEJF_02940 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NKCFMEJF_02941 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
NKCFMEJF_02942 2.2e-179 oxyR3 K LysR substrate binding domain
NKCFMEJF_02943 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NKCFMEJF_02944 2.9e-145 ycgL S Predicted nucleotidyltransferase
NKCFMEJF_02945 5.1e-170 ycgM E Proline dehydrogenase
NKCFMEJF_02946 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NKCFMEJF_02947 5.3e-212 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKCFMEJF_02948 1e-24 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKCFMEJF_02949 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NKCFMEJF_02950 2.6e-147 ycgQ S membrane
NKCFMEJF_02951 1.2e-139 ycgR S permeases
NKCFMEJF_02952 5.7e-163 I alpha/beta hydrolase fold
NKCFMEJF_02953 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NKCFMEJF_02954 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NKCFMEJF_02955 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NKCFMEJF_02956 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NKCFMEJF_02957 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKCFMEJF_02958 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NKCFMEJF_02959 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
NKCFMEJF_02960 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NKCFMEJF_02961 5.5e-109 yciB M ErfK YbiS YcfS YnhG
NKCFMEJF_02962 1.4e-228 yciC S GTPases (G3E family)
NKCFMEJF_02963 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NKCFMEJF_02964 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NKCFMEJF_02967 3.3e-77 yckC S membrane
NKCFMEJF_02968 3.5e-52 yckD S Protein of unknown function (DUF2680)
NKCFMEJF_02969 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NKCFMEJF_02970 3.4e-70 nin S Competence protein J (ComJ)
NKCFMEJF_02971 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
NKCFMEJF_02972 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
NKCFMEJF_02973 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NKCFMEJF_02974 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NKCFMEJF_02975 1.3e-63 hxlR K transcriptional
NKCFMEJF_02978 9.3e-116
NKCFMEJF_02979 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NKCFMEJF_02980 6.2e-145 S Phage tail protein
NKCFMEJF_02981 0.0 S Pfam Transposase IS66
NKCFMEJF_02982 6.4e-115
NKCFMEJF_02983 0.0 G Exopolysaccharide biosynthesis protein
NKCFMEJF_02984 6.5e-164
NKCFMEJF_02986 1.6e-186 3.5.1.28 M Ami_2
NKCFMEJF_02987 4.4e-32 bhlA S BhlA holin family
NKCFMEJF_02988 5.5e-40 S SPP1 phage holin
NKCFMEJF_02989 3.4e-74 O protein disulfide oxidoreductase activity
NKCFMEJF_02990 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NKCFMEJF_02991 1.2e-70 CO cell redox homeostasis
NKCFMEJF_02992 0.0 V Peptidase C39 family
NKCFMEJF_02995 1.9e-239 S impB/mucB/samB family C-terminal domain
NKCFMEJF_02996 5.8e-55 S YolD-like protein
NKCFMEJF_02997 2.5e-42
NKCFMEJF_02999 6.8e-09 S Domain of unknown function (DUF4879)
NKCFMEJF_03001 2.8e-99 J Acetyltransferase (GNAT) domain
NKCFMEJF_03002 3.2e-109 yokK S SMI1 / KNR4 family
NKCFMEJF_03003 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
NKCFMEJF_03004 1.2e-302 UW nuclease activity
NKCFMEJF_03005 6.7e-92 yokH G SMI1 / KNR4 family
NKCFMEJF_03006 4.1e-203
NKCFMEJF_03007 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
NKCFMEJF_03008 1.1e-83 S Bacterial PH domain
NKCFMEJF_03009 8.4e-156 aacC 2.3.1.81 V aminoglycoside
NKCFMEJF_03012 8.9e-95
NKCFMEJF_03013 1.6e-107
NKCFMEJF_03014 2.7e-307 yokA L Recombinase
NKCFMEJF_03015 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
NKCFMEJF_03016 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NKCFMEJF_03017 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NKCFMEJF_03018 1.6e-70 ypoP K transcriptional
NKCFMEJF_03019 2.6e-223 mepA V MATE efflux family protein
NKCFMEJF_03020 5.5e-29 ypmT S Uncharacterized ympT
NKCFMEJF_03021 5e-99 ypmS S protein conserved in bacteria
NKCFMEJF_03022 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NKCFMEJF_03023 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NKCFMEJF_03024 3.1e-40 ypmP S Protein of unknown function (DUF2535)
NKCFMEJF_03025 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NKCFMEJF_03026 1.6e-185 pspF K Transcriptional regulator
NKCFMEJF_03027 4.2e-110 hlyIII S protein, Hemolysin III
NKCFMEJF_03028 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NKCFMEJF_03029 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NKCFMEJF_03030 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NKCFMEJF_03031 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NKCFMEJF_03032 7.8e-114 ypjP S YpjP-like protein
NKCFMEJF_03033 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NKCFMEJF_03034 1.7e-75 yphP S Belongs to the UPF0403 family
NKCFMEJF_03035 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NKCFMEJF_03036 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
NKCFMEJF_03037 3.1e-110 ypgQ S phosphohydrolase
NKCFMEJF_03038 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NKCFMEJF_03039 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NKCFMEJF_03040 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NKCFMEJF_03041 7.9e-31 cspD K Cold-shock protein
NKCFMEJF_03042 3.8e-16 degR
NKCFMEJF_03043 8.1e-31 S Protein of unknown function (DUF2564)
NKCFMEJF_03044 2.6e-27 ypeQ S Zinc-finger
NKCFMEJF_03045 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NKCFMEJF_03046 1.1e-121 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NKCFMEJF_03047 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
NKCFMEJF_03049 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NKCFMEJF_03050 2e-07
NKCFMEJF_03051 1e-38 ypbS S Protein of unknown function (DUF2533)
NKCFMEJF_03052 0.0 ypbR S Dynamin family
NKCFMEJF_03053 5.1e-87 ypbQ S protein conserved in bacteria
NKCFMEJF_03054 4.4e-208 bcsA Q Naringenin-chalcone synthase
NKCFMEJF_03055 1.6e-228 pbuX F xanthine
NKCFMEJF_03056 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NKCFMEJF_03057 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NKCFMEJF_03058 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NKCFMEJF_03059 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NKCFMEJF_03060 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NKCFMEJF_03061 3.9e-187 ptxS K transcriptional
NKCFMEJF_03062 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NKCFMEJF_03063 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKCFMEJF_03064 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NKCFMEJF_03066 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NKCFMEJF_03067 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NKCFMEJF_03068 3.3e-92 ypsA S Belongs to the UPF0398 family
NKCFMEJF_03069 1.3e-237 yprB L RNase_H superfamily
NKCFMEJF_03070 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NKCFMEJF_03071 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NKCFMEJF_03072 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
NKCFMEJF_03073 1.2e-48 yppG S YppG-like protein
NKCFMEJF_03075 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
NKCFMEJF_03078 2.6e-188 yppC S Protein of unknown function (DUF2515)
NKCFMEJF_03079 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NKCFMEJF_03080 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NKCFMEJF_03081 4.7e-93 ypoC
NKCFMEJF_03082 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NKCFMEJF_03083 5.7e-129 dnaD L DNA replication protein DnaD
NKCFMEJF_03084 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NKCFMEJF_03085 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NKCFMEJF_03086 3.4e-80 ypmB S protein conserved in bacteria
NKCFMEJF_03087 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NKCFMEJF_03088 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NKCFMEJF_03089 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NKCFMEJF_03090 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NKCFMEJF_03091 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NKCFMEJF_03092 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NKCFMEJF_03093 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NKCFMEJF_03094 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NKCFMEJF_03095 6.9e-130 bshB1 S proteins, LmbE homologs
NKCFMEJF_03096 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NKCFMEJF_03097 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NKCFMEJF_03098 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NKCFMEJF_03099 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NKCFMEJF_03100 6.1e-143 ypjB S sporulation protein
NKCFMEJF_03101 4.4e-98 ypjA S membrane
NKCFMEJF_03102 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NKCFMEJF_03103 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NKCFMEJF_03104 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NKCFMEJF_03105 8.5e-78 ypiF S Protein of unknown function (DUF2487)
NKCFMEJF_03106 2.8e-99 ypiB S Belongs to the UPF0302 family
NKCFMEJF_03107 4.1e-234 S COG0457 FOG TPR repeat
NKCFMEJF_03108 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NKCFMEJF_03109 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NKCFMEJF_03110 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NKCFMEJF_03111 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NKCFMEJF_03112 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NKCFMEJF_03113 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NKCFMEJF_03114 2.3e-115 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NKCFMEJF_03115 9.7e-170 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NKCFMEJF_03116 7.3e-278 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NKCFMEJF_03117 3.7e-61 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NKCFMEJF_03118 7.4e-200 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NKCFMEJF_03119 7.2e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NKCFMEJF_03120 3.2e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NKCFMEJF_03121 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NKCFMEJF_03122 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NKCFMEJF_03123 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NKCFMEJF_03124 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NKCFMEJF_03125 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NKCFMEJF_03126 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NKCFMEJF_03127 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NKCFMEJF_03128 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NKCFMEJF_03129 5.4e-138 yphF
NKCFMEJF_03130 1.6e-18 yphE S Protein of unknown function (DUF2768)
NKCFMEJF_03131 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NKCFMEJF_03132 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NKCFMEJF_03133 1.6e-28 ypzH
NKCFMEJF_03134 2.5e-161 seaA S YIEGIA protein
NKCFMEJF_03135 1.3e-102 yphA
NKCFMEJF_03136 1e-07 S YpzI-like protein
NKCFMEJF_03137 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NKCFMEJF_03138 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
NKCFMEJF_03139 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NKCFMEJF_03140 1.8e-23 S Family of unknown function (DUF5359)
NKCFMEJF_03141 9.2e-113 ypfA M Flagellar protein YcgR
NKCFMEJF_03142 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NKCFMEJF_03143 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NKCFMEJF_03144 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
NKCFMEJF_03145 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NKCFMEJF_03146 7.3e-247 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NKCFMEJF_03147 7.7e-103 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NKCFMEJF_03148 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
NKCFMEJF_03149 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NKCFMEJF_03150 4.6e-81 ypbE M Lysin motif
NKCFMEJF_03151 2.2e-100 ypbD S metal-dependent membrane protease
NKCFMEJF_03152 3.2e-286 recQ 3.6.4.12 L DNA helicase
NKCFMEJF_03153 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
NKCFMEJF_03154 4.7e-41 fer C Ferredoxin
NKCFMEJF_03155 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NKCFMEJF_03156 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKCFMEJF_03157 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NKCFMEJF_03158 6.8e-201 rsiX
NKCFMEJF_03159 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NKCFMEJF_03160 0.0 resE 2.7.13.3 T Histidine kinase
NKCFMEJF_03161 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_03162 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NKCFMEJF_03163 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NKCFMEJF_03164 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NKCFMEJF_03165 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NKCFMEJF_03166 1.9e-87 spmB S Spore maturation protein
NKCFMEJF_03167 3.5e-103 spmA S Spore maturation protein
NKCFMEJF_03168 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NKCFMEJF_03169 8.4e-84 ypuI S Protein of unknown function (DUF3907)
NKCFMEJF_03172 1.1e-16 ydhU P Manganese containing catalase
NKCFMEJF_03173 8.7e-78 ydhU P Catalase
NKCFMEJF_03174 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NKCFMEJF_03175 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
NKCFMEJF_03176 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NKCFMEJF_03177 3.9e-133 ydhQ K UTRA
NKCFMEJF_03178 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NKCFMEJF_03179 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKCFMEJF_03180 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NKCFMEJF_03181 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NKCFMEJF_03182 2.3e-199 pbuE EGP Major facilitator Superfamily
NKCFMEJF_03183 1.7e-99 ydhK M Protein of unknown function (DUF1541)
NKCFMEJF_03184 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NKCFMEJF_03185 4.1e-86 K Acetyltransferase (GNAT) domain
NKCFMEJF_03187 4.6e-69 frataxin S Domain of unknown function (DU1801)
NKCFMEJF_03188 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NKCFMEJF_03189 1.9e-127
NKCFMEJF_03190 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NKCFMEJF_03191 3.3e-244 ydhD M Glycosyl hydrolase
NKCFMEJF_03192 6.5e-122 ydhC K FCD
NKCFMEJF_03193 1.2e-121 ydhB S membrane transporter protein
NKCFMEJF_03194 2.5e-209 tcaB EGP Major facilitator Superfamily
NKCFMEJF_03195 1.1e-69 ydgJ K Winged helix DNA-binding domain
NKCFMEJF_03196 1e-113 drgA C nitroreductase
NKCFMEJF_03197 0.0 ydgH S drug exporters of the RND superfamily
NKCFMEJF_03198 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
NKCFMEJF_03199 4.6e-91 dinB S DinB family
NKCFMEJF_03200 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NKCFMEJF_03201 4.2e-308 expZ S ABC transporter
NKCFMEJF_03202 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
NKCFMEJF_03203 1.9e-53 S DoxX-like family
NKCFMEJF_03204 1.5e-101 K Bacterial regulatory proteins, tetR family
NKCFMEJF_03205 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NKCFMEJF_03206 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
NKCFMEJF_03207 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
NKCFMEJF_03208 5.2e-122 ydfS S Protein of unknown function (DUF421)
NKCFMEJF_03209 4.4e-118 ydfR S Protein of unknown function (DUF421)
NKCFMEJF_03211 6.3e-29
NKCFMEJF_03212 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NKCFMEJF_03213 1.3e-57 traF CO Thioredoxin
NKCFMEJF_03214 8.8e-63 mhqP S DoxX
NKCFMEJF_03215 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NKCFMEJF_03216 9.6e-112 ydfN C nitroreductase
NKCFMEJF_03217 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKCFMEJF_03218 3.2e-147 K Bacterial transcription activator, effector binding domain
NKCFMEJF_03219 5.9e-118 S Protein of unknown function (DUF554)
NKCFMEJF_03220 1.9e-177 S Alpha/beta hydrolase family
NKCFMEJF_03221 0.0 ydfJ S drug exporters of the RND superfamily
NKCFMEJF_03222 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKCFMEJF_03223 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
NKCFMEJF_03225 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NKCFMEJF_03226 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NKCFMEJF_03227 5.9e-117 ydfE S Flavin reductase like domain
NKCFMEJF_03228 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKCFMEJF_03229 1e-162 ydfC EG EamA-like transporter family
NKCFMEJF_03230 7.2e-149 ydfB J GNAT acetyltransferase
NKCFMEJF_03231 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NKCFMEJF_03232 1.3e-57 arsR K transcriptional
NKCFMEJF_03233 8.4e-105 ydeS K Transcriptional regulator
NKCFMEJF_03234 1.2e-195 ydeR EGP Major facilitator Superfamily
NKCFMEJF_03235 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
NKCFMEJF_03236 4.8e-69 ydeP K Transcriptional regulator
NKCFMEJF_03237 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NKCFMEJF_03238 1.1e-58 K HxlR-like helix-turn-helix
NKCFMEJF_03239 8.6e-107 ydeN S Serine hydrolase
NKCFMEJF_03240 4.2e-74 maoC I N-terminal half of MaoC dehydratase
NKCFMEJF_03241 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKCFMEJF_03242 1.8e-153 ydeK EG -transporter
NKCFMEJF_03243 4e-116
NKCFMEJF_03244 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NKCFMEJF_03245 2.9e-47 ydeH
NKCFMEJF_03246 3.4e-220 ydeG EGP Major facilitator superfamily
NKCFMEJF_03247 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKCFMEJF_03248 2.5e-166 ydeE K AraC family transcriptional regulator
NKCFMEJF_03249 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NKCFMEJF_03250 1.1e-166 rhaS5 K AraC-like ligand binding domain
NKCFMEJF_03251 4.6e-35 ydzE EG spore germination
NKCFMEJF_03252 6.1e-79 carD K Transcription factor
NKCFMEJF_03253 8.7e-30 cspL K Cold shock
NKCFMEJF_03254 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NKCFMEJF_03259 5e-227 ydeG EGP Major facilitator Superfamily
NKCFMEJF_03260 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
NKCFMEJF_03261 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
NKCFMEJF_03262 3.9e-78 lrpB K transcriptional
NKCFMEJF_03263 2.4e-71 lrpA K transcriptional
NKCFMEJF_03264 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKCFMEJF_03272 1.6e-84 ydcK S Belongs to the SprT family
NKCFMEJF_03273 0.0 yhgF K COG2183 Transcriptional accessory protein
NKCFMEJF_03274 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
NKCFMEJF_03275 1.5e-82 ydcG S EVE domain
NKCFMEJF_03279 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NKCFMEJF_03280 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NKCFMEJF_03281 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NKCFMEJF_03282 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NKCFMEJF_03283 7.1e-189 rsbU 3.1.3.3 KT phosphatase
NKCFMEJF_03284 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NKCFMEJF_03285 5.2e-57 rsbS T antagonist
NKCFMEJF_03286 1.3e-143 rsbR T Positive regulator of sigma-B
NKCFMEJF_03287 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NKCFMEJF_03288 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NKCFMEJF_03289 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NKCFMEJF_03290 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NKCFMEJF_03291 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NKCFMEJF_03292 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NKCFMEJF_03293 2.2e-263 ydbT S Membrane
NKCFMEJF_03294 2.1e-82 ydbS S Bacterial PH domain
NKCFMEJF_03295 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NKCFMEJF_03296 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NKCFMEJF_03297 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NKCFMEJF_03298 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NKCFMEJF_03299 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NKCFMEJF_03300 2.2e-07 S Fur-regulated basic protein A
NKCFMEJF_03301 1.1e-18 S Fur-regulated basic protein B
NKCFMEJF_03302 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NKCFMEJF_03303 2.7e-52 ydbL
NKCFMEJF_03304 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NKCFMEJF_03305 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
NKCFMEJF_03306 4.4e-181 ydbI S AI-2E family transporter
NKCFMEJF_03307 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NKCFMEJF_03308 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
NKCFMEJF_03309 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NKCFMEJF_03310 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NKCFMEJF_03311 3.2e-155 ydbD P Catalase
NKCFMEJF_03312 2.8e-63 ydbC S Domain of unknown function (DUF4937
NKCFMEJF_03313 8.9e-59 ydbB G Cupin domain
NKCFMEJF_03315 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NKCFMEJF_03316 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NKCFMEJF_03318 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NKCFMEJF_03319 9.4e-40
NKCFMEJF_03320 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NKCFMEJF_03321 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NKCFMEJF_03322 0.0 ydaO E amino acid
NKCFMEJF_03323 0.0 ydaN S Bacterial cellulose synthase subunit
NKCFMEJF_03324 4.5e-233 ydaM M Glycosyl transferase family group 2
NKCFMEJF_03325 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NKCFMEJF_03326 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
NKCFMEJF_03327 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NKCFMEJF_03328 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NKCFMEJF_03329 2.5e-74 lrpC K Transcriptional regulator
NKCFMEJF_03330 5.1e-47 ydzA EGP Major facilitator Superfamily
NKCFMEJF_03331 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NKCFMEJF_03332 6.8e-77 ydaG 1.4.3.5 S general stress protein
NKCFMEJF_03333 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NKCFMEJF_03334 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NKCFMEJF_03335 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKCFMEJF_03336 1.1e-99 ydaC Q Methyltransferase domain
NKCFMEJF_03337 1.4e-294 ydaB IQ acyl-CoA ligase
NKCFMEJF_03338 0.0 mtlR K transcriptional regulator, MtlR
NKCFMEJF_03339 2.8e-176 ydhF S Oxidoreductase
NKCFMEJF_03340 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NKCFMEJF_03341 1.4e-49 yczJ S biosynthesis
NKCFMEJF_03343 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
NKCFMEJF_03344 1.2e-132 kipR K Transcriptional regulator
NKCFMEJF_03345 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NKCFMEJF_03346 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NKCFMEJF_03347 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
NKCFMEJF_03348 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NKCFMEJF_03349 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
NKCFMEJF_03350 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NKCFMEJF_03352 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NKCFMEJF_03353 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NKCFMEJF_03354 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NKCFMEJF_03355 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NKCFMEJF_03356 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NKCFMEJF_03357 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NKCFMEJF_03358 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NKCFMEJF_03359 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NKCFMEJF_03360 7.3e-56
NKCFMEJF_03361 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NKCFMEJF_03362 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NKCFMEJF_03363 1.3e-100 ycnI S protein conserved in bacteria
NKCFMEJF_03364 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKCFMEJF_03365 6.1e-149 glcU U Glucose uptake
NKCFMEJF_03366 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKCFMEJF_03367 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKCFMEJF_03368 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NKCFMEJF_03369 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NKCFMEJF_03370 1.6e-45 ycnE S Monooxygenase
NKCFMEJF_03371 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NKCFMEJF_03372 6.5e-154 ycnC K Transcriptional regulator
NKCFMEJF_03373 1.4e-251 ycnB EGP Major facilitator Superfamily
NKCFMEJF_03374 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NKCFMEJF_03375 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NKCFMEJF_03376 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_03377 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NKCFMEJF_03378 1.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
NKCFMEJF_03381 5.2e-71 S aspartate phosphatase
NKCFMEJF_03382 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NKCFMEJF_03383 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_03384 1.7e-204 yclI V ABC transporter (permease) YclI
NKCFMEJF_03385 3.9e-122 yclH P ABC transporter
NKCFMEJF_03386 9.9e-200 gerKB F Spore germination protein
NKCFMEJF_03387 1.3e-232 gerKC S spore germination
NKCFMEJF_03388 6.8e-282 gerKA EG Spore germination protein
NKCFMEJF_03390 2.9e-310 yclG M Pectate lyase superfamily protein
NKCFMEJF_03391 1.5e-267 dtpT E amino acid peptide transporter
NKCFMEJF_03392 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
NKCFMEJF_03393 1.1e-83 yclD
NKCFMEJF_03394 4e-39 bsdD 4.1.1.61 S response to toxic substance
NKCFMEJF_03395 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NKCFMEJF_03396 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NKCFMEJF_03397 4.9e-162 bsdA K LysR substrate binding domain
NKCFMEJF_03398 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NKCFMEJF_03399 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NKCFMEJF_03400 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NKCFMEJF_03401 4.4e-115 yczE S membrane
NKCFMEJF_03402 4.4e-75 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NKCFMEJF_03403 4.4e-255 ycxD K GntR family transcriptional regulator
NKCFMEJF_03404 7.4e-164 ycxC EG EamA-like transporter family
NKCFMEJF_03405 4.9e-91 S YcxB-like protein
NKCFMEJF_03406 4.2e-228 EGP Major Facilitator Superfamily
NKCFMEJF_03407 5.7e-140 srfAD Q thioesterase
NKCFMEJF_03408 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NKCFMEJF_03409 7.2e-250 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_03410 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NKCFMEJF_03411 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NKCFMEJF_03412 1.7e-190 spsG M Spore Coat
NKCFMEJF_03413 9.7e-132 spsF M Spore Coat
NKCFMEJF_03414 3.2e-214 spsE 2.5.1.56 M acid synthase
NKCFMEJF_03415 4e-164 spsD 2.3.1.210 K Spore Coat
NKCFMEJF_03416 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
NKCFMEJF_03417 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
NKCFMEJF_03418 2.8e-145 spsA M Spore Coat
NKCFMEJF_03419 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NKCFMEJF_03420 4.3e-59 ywdK S small membrane protein
NKCFMEJF_03421 3.2e-209 ywdJ F Xanthine uracil
NKCFMEJF_03422 1.2e-13 ywdJ F Xanthine uracil
NKCFMEJF_03423 7.7e-49 ywdI S Family of unknown function (DUF5327)
NKCFMEJF_03424 7.8e-252 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NKCFMEJF_03425 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NKCFMEJF_03426 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
NKCFMEJF_03428 1.4e-113 ywdD
NKCFMEJF_03429 1.3e-57 pex K Transcriptional regulator PadR-like family
NKCFMEJF_03430 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NKCFMEJF_03431 2e-28 ywdA
NKCFMEJF_03432 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NKCFMEJF_03433 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKCFMEJF_03434 1e-139 focA P Formate/nitrite transporter
NKCFMEJF_03435 2.4e-150 sacT K transcriptional antiterminator
NKCFMEJF_03437 0.0 vpr O Belongs to the peptidase S8 family
NKCFMEJF_03438 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKCFMEJF_03439 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NKCFMEJF_03440 2.9e-202 rodA D Belongs to the SEDS family
NKCFMEJF_03441 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NKCFMEJF_03442 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NKCFMEJF_03443 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NKCFMEJF_03444 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NKCFMEJF_03445 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NKCFMEJF_03446 1e-35 ywzA S membrane
NKCFMEJF_03447 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NKCFMEJF_03448 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NKCFMEJF_03449 9.5e-60 gtcA S GtrA-like protein
NKCFMEJF_03450 2.2e-122 ywcC K transcriptional regulator
NKCFMEJF_03452 9.8e-49 ywcB S Protein of unknown function, DUF485
NKCFMEJF_03453 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKCFMEJF_03454 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NKCFMEJF_03455 2.6e-225 ywbN P Dyp-type peroxidase family protein
NKCFMEJF_03456 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
NKCFMEJF_03457 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
NKCFMEJF_03458 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NKCFMEJF_03459 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NKCFMEJF_03460 4.3e-153 ywbI K Transcriptional regulator
NKCFMEJF_03461 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NKCFMEJF_03462 2.3e-111 ywbG M effector of murein hydrolase
NKCFMEJF_03463 1.9e-209 ywbF EGP Major facilitator Superfamily
NKCFMEJF_03464 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
NKCFMEJF_03465 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
NKCFMEJF_03466 4.4e-67 ywbC 4.4.1.5 E glyoxalase
NKCFMEJF_03467 1.8e-127 ywbB S Protein of unknown function (DUF2711)
NKCFMEJF_03468 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKCFMEJF_03469 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
NKCFMEJF_03470 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKCFMEJF_03471 4e-153 sacY K transcriptional antiterminator
NKCFMEJF_03472 7e-169 gspA M General stress
NKCFMEJF_03473 1.7e-128 ywaF S Integral membrane protein
NKCFMEJF_03474 8.1e-88 ywaE K Transcriptional regulator
NKCFMEJF_03475 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NKCFMEJF_03476 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NKCFMEJF_03477 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NKCFMEJF_03478 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NKCFMEJF_03479 5e-14 S D-Ala-teichoic acid biosynthesis protein
NKCFMEJF_03480 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_03481 1.2e-232 dltB M membrane protein involved in D-alanine export
NKCFMEJF_03482 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_03483 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NKCFMEJF_03484 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_03485 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NKCFMEJF_03486 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NKCFMEJF_03487 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NKCFMEJF_03488 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NKCFMEJF_03489 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NKCFMEJF_03490 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NKCFMEJF_03491 1.1e-19 yxzF
NKCFMEJF_03492 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NKCFMEJF_03493 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NKCFMEJF_03494 2.1e-216 yxlH EGP Major facilitator Superfamily
NKCFMEJF_03495 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NKCFMEJF_03496 5.1e-167 yxlF V ABC transporter, ATP-binding protein
NKCFMEJF_03497 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NKCFMEJF_03498 1.2e-31
NKCFMEJF_03499 3.9e-48 yxlC S Family of unknown function (DUF5345)
NKCFMEJF_03500 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NKCFMEJF_03501 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NKCFMEJF_03502 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NKCFMEJF_03503 0.0 cydD V ATP-binding protein
NKCFMEJF_03504 0.0 cydD V ATP-binding
NKCFMEJF_03505 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NKCFMEJF_03506 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
NKCFMEJF_03507 1.5e-229 cimH C COG3493 Na citrate symporter
NKCFMEJF_03508 0.0 3.4.24.84 O Peptidase family M48
NKCFMEJF_03510 3e-156 yxkH G Polysaccharide deacetylase
NKCFMEJF_03511 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NKCFMEJF_03512 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
NKCFMEJF_03513 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKCFMEJF_03514 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NKCFMEJF_03515 4.1e-73 yxkC S Domain of unknown function (DUF4352)
NKCFMEJF_03516 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NKCFMEJF_03517 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
NKCFMEJF_03518 1.9e-166 yxjO K LysR substrate binding domain
NKCFMEJF_03519 2.4e-78 S Protein of unknown function (DUF1453)
NKCFMEJF_03520 1.5e-193 yxjM T Signal transduction histidine kinase
NKCFMEJF_03521 8.9e-116 K helix_turn_helix, Lux Regulon
NKCFMEJF_03522 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NKCFMEJF_03525 1e-87 yxjI S LURP-one-related
NKCFMEJF_03526 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
NKCFMEJF_03527 1e-220 yxjG 2.1.1.14 E Methionine synthase
NKCFMEJF_03528 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NKCFMEJF_03529 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NKCFMEJF_03530 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NKCFMEJF_03531 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NKCFMEJF_03532 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
NKCFMEJF_03533 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NKCFMEJF_03534 1.2e-22 T Domain of unknown function (DUF4163)
NKCFMEJF_03535 2.7e-48 yxiS
NKCFMEJF_03536 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NKCFMEJF_03537 6.6e-224 citH C Citrate transporter
NKCFMEJF_03538 5e-144 exoK GH16 M licheninase activity
NKCFMEJF_03539 8.3e-151 licT K transcriptional antiterminator
NKCFMEJF_03540 6.6e-114
NKCFMEJF_03541 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
NKCFMEJF_03542 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NKCFMEJF_03543 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NKCFMEJF_03546 1.6e-48 yxiJ S YxiJ-like protein
NKCFMEJF_03547 1.2e-96 yxiI S Protein of unknown function (DUF2716)
NKCFMEJF_03548 3.8e-81
NKCFMEJF_03549 4.9e-46
NKCFMEJF_03550 3.7e-75 yxiG
NKCFMEJF_03551 6.4e-63
NKCFMEJF_03552 1.7e-84
NKCFMEJF_03553 1.5e-71 yxxG
NKCFMEJF_03554 0.0 wapA M COG3209 Rhs family protein
NKCFMEJF_03555 2.9e-168 yxxF EG EamA-like transporter family
NKCFMEJF_03556 1.1e-72 yxiE T Belongs to the universal stress protein A family
NKCFMEJF_03557 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NKCFMEJF_03558 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NKCFMEJF_03559 3.6e-51
NKCFMEJF_03560 2.2e-78 S SMI1 / KNR4 family
NKCFMEJF_03561 0.0 S nuclease activity
NKCFMEJF_03562 3.6e-39 yxiC S Family of unknown function (DUF5344)
NKCFMEJF_03563 2.1e-21 S Domain of unknown function (DUF5082)
NKCFMEJF_03564 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NKCFMEJF_03565 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NKCFMEJF_03566 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
NKCFMEJF_03567 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NKCFMEJF_03568 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NKCFMEJF_03569 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NKCFMEJF_03570 6.1e-252 lysP E amino acid
NKCFMEJF_03571 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NKCFMEJF_03572 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NKCFMEJF_03573 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NKCFMEJF_03574 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NKCFMEJF_03575 3e-153 yxxB S Domain of Unknown Function (DUF1206)
NKCFMEJF_03576 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
NKCFMEJF_03577 2e-255 yxeQ S MmgE/PrpD family
NKCFMEJF_03578 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
NKCFMEJF_03579 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NKCFMEJF_03580 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
NKCFMEJF_03581 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NKCFMEJF_03582 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKCFMEJF_03583 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NKCFMEJF_03585 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NKCFMEJF_03586 6.2e-151 yidA S hydrolases of the HAD superfamily
NKCFMEJF_03589 1.3e-20 yxeE
NKCFMEJF_03590 1.9e-16 yxeD
NKCFMEJF_03591 8.5e-69
NKCFMEJF_03592 6e-177 fhuD P ABC transporter
NKCFMEJF_03593 1.5e-58 yxeA S Protein of unknown function (DUF1093)
NKCFMEJF_03594 0.0 yxdM V ABC transporter (permease)
NKCFMEJF_03595 9.4e-141 yxdL V ABC transporter, ATP-binding protein
NKCFMEJF_03596 1.3e-182 T PhoQ Sensor
NKCFMEJF_03597 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_03598 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NKCFMEJF_03599 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NKCFMEJF_03600 2.3e-167 iolH G Xylose isomerase-like TIM barrel
NKCFMEJF_03601 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NKCFMEJF_03602 1.3e-235 iolF EGP Major facilitator Superfamily
NKCFMEJF_03603 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NKCFMEJF_03604 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NKCFMEJF_03605 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NKCFMEJF_03606 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NKCFMEJF_03607 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NKCFMEJF_03608 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NKCFMEJF_03609 3.7e-176 iolS C Aldo keto reductase
NKCFMEJF_03611 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NKCFMEJF_03612 2.3e-246 csbC EGP Major facilitator Superfamily
NKCFMEJF_03613 0.0 htpG O Molecular chaperone. Has ATPase activity
NKCFMEJF_03615 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
NKCFMEJF_03616 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
NKCFMEJF_03617 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NKCFMEJF_03618 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
NKCFMEJF_03619 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
NKCFMEJF_03620 3.3e-127 yxbB Q Met-10+ like-protein
NKCFMEJF_03621 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
NKCFMEJF_03622 1.1e-86 yxnB
NKCFMEJF_03623 0.0 asnB 6.3.5.4 E Asparagine synthase
NKCFMEJF_03624 7.6e-214 yxaM U MFS_1 like family
NKCFMEJF_03625 6.8e-93 S PQQ-like domain
NKCFMEJF_03626 3.5e-65 S Family of unknown function (DUF5391)
NKCFMEJF_03627 1.1e-75 yxaI S membrane protein domain
NKCFMEJF_03628 1.4e-228 P Protein of unknown function (DUF418)
NKCFMEJF_03629 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
NKCFMEJF_03630 7.1e-101 yxaF K Transcriptional regulator
NKCFMEJF_03631 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_03632 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NKCFMEJF_03633 5.2e-50 S LrgA family
NKCFMEJF_03634 2.6e-118 yxaC M effector of murein hydrolase
NKCFMEJF_03635 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
NKCFMEJF_03636 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NKCFMEJF_03637 7.3e-127 gntR K transcriptional
NKCFMEJF_03638 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NKCFMEJF_03639 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
NKCFMEJF_03640 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NKCFMEJF_03641 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NKCFMEJF_03642 3.8e-287 ahpF O Alkyl hydroperoxide reductase
NKCFMEJF_03643 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NKCFMEJF_03644 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
NKCFMEJF_03645 1.3e-128 yydK K Transcriptional regulator
NKCFMEJF_03646 7.6e-13
NKCFMEJF_03647 3.3e-119 S ABC-2 family transporter protein
NKCFMEJF_03648 1.8e-110 prrC P ABC transporter
NKCFMEJF_03649 8.4e-134 yydH O Peptidase M50
NKCFMEJF_03650 7.7e-185 S Radical SAM superfamily
NKCFMEJF_03651 8e-12
NKCFMEJF_03652 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NKCFMEJF_03653 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
NKCFMEJF_03654 3.5e-65
NKCFMEJF_03655 7.3e-280 S Calcineurin-like phosphoesterase
NKCFMEJF_03656 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NKCFMEJF_03657 1.1e-09 S YyzF-like protein
NKCFMEJF_03658 4.2e-71
NKCFMEJF_03659 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NKCFMEJF_03661 2.1e-33 yycQ S Protein of unknown function (DUF2651)
NKCFMEJF_03662 1.6e-221 yycP
NKCFMEJF_03663 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NKCFMEJF_03664 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
NKCFMEJF_03665 5e-188 S aspartate phosphatase
NKCFMEJF_03667 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NKCFMEJF_03668 9.7e-261 rocE E amino acid
NKCFMEJF_03669 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NKCFMEJF_03670 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NKCFMEJF_03671 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NKCFMEJF_03672 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NKCFMEJF_03673 7.3e-155 yycI S protein conserved in bacteria
NKCFMEJF_03674 3.6e-260 yycH S protein conserved in bacteria
NKCFMEJF_03675 0.0 vicK 2.7.13.3 T Histidine kinase
NKCFMEJF_03676 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NKCFMEJF_03681 1.1e-245 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NKCFMEJF_03682 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKCFMEJF_03683 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NKCFMEJF_03684 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NKCFMEJF_03686 1.9e-15 yycC K YycC-like protein
NKCFMEJF_03687 8.4e-221 yeaN P COG2807 Cyanate permease
NKCFMEJF_03688 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NKCFMEJF_03689 2.2e-73 rplI J binds to the 23S rRNA
NKCFMEJF_03690 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NKCFMEJF_03691 2.9e-160 yybS S membrane
NKCFMEJF_03693 3.9e-84 cotF M Spore coat protein
NKCFMEJF_03694 1.4e-68 ydeP3 K Transcriptional regulator
NKCFMEJF_03695 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NKCFMEJF_03696 1.3e-70
NKCFMEJF_03698 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NKCFMEJF_03699 1e-16
NKCFMEJF_03700 1.3e-78 yybN S Protein of unknown function (DUF2712)
NKCFMEJF_03701 4.1e-125
NKCFMEJF_03702 9e-122
NKCFMEJF_03703 2e-127 S Protein of unknown function (DUF2705)
NKCFMEJF_03704 2.6e-115 V ATPases associated with a variety of cellular activities
NKCFMEJF_03705 6.2e-132
NKCFMEJF_03706 5.9e-67 yybH S SnoaL-like domain
NKCFMEJF_03707 3e-124 yybG S Pentapeptide repeat-containing protein
NKCFMEJF_03708 5.5e-220 ynfM EGP Major facilitator Superfamily
NKCFMEJF_03709 2.1e-165 yybE K Transcriptional regulator
NKCFMEJF_03710 2e-79 yjcF S Acetyltransferase (GNAT) domain
NKCFMEJF_03711 2.7e-77 yybC
NKCFMEJF_03712 3e-127 S Metallo-beta-lactamase superfamily
NKCFMEJF_03713 5.6e-77 yybA 2.3.1.57 K transcriptional
NKCFMEJF_03714 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
NKCFMEJF_03715 1.5e-101 yyaS S Membrane
NKCFMEJF_03716 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
NKCFMEJF_03717 5.4e-67 yyaQ S YjbR
NKCFMEJF_03718 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
NKCFMEJF_03719 1.7e-249 tetL EGP Major facilitator Superfamily
NKCFMEJF_03720 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
NKCFMEJF_03721 5.1e-61 yyaN K MerR HTH family regulatory protein
NKCFMEJF_03722 3.3e-161 yyaM EG EamA-like transporter family
NKCFMEJF_03723 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NKCFMEJF_03724 9.5e-169 yyaK S CAAX protease self-immunity
NKCFMEJF_03725 3.8e-246 EGP Major facilitator superfamily
NKCFMEJF_03726 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NKCFMEJF_03727 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NKCFMEJF_03728 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NKCFMEJF_03729 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
NKCFMEJF_03730 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NKCFMEJF_03731 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NKCFMEJF_03732 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NKCFMEJF_03733 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NKCFMEJF_03734 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKCFMEJF_03735 2.3e-33 yyzM S protein conserved in bacteria
NKCFMEJF_03736 8.1e-177 yyaD S Membrane
NKCFMEJF_03737 1.6e-111 yyaC S Sporulation protein YyaC
NKCFMEJF_03738 2.1e-149 spo0J K Belongs to the ParB family
NKCFMEJF_03739 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NKCFMEJF_03740 1.5e-74 S Bacterial PH domain
NKCFMEJF_03741 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NKCFMEJF_03742 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NKCFMEJF_03743 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NKCFMEJF_03744 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NKCFMEJF_03745 6.5e-108 jag S single-stranded nucleic acid binding R3H
NKCFMEJF_03746 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NKCFMEJF_03747 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NKCFMEJF_03748 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NKCFMEJF_03749 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NKCFMEJF_03750 2.4e-33 yaaA S S4 domain
NKCFMEJF_03751 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NKCFMEJF_03752 1.8e-37 yaaB S Domain of unknown function (DUF370)
NKCFMEJF_03753 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NKCFMEJF_03754 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NKCFMEJF_03755 9.5e-100 M Parallel beta-helix repeats
NKCFMEJF_03760 1.3e-170
NKCFMEJF_03761 7.6e-180 L AAA domain
NKCFMEJF_03762 1.4e-86
NKCFMEJF_03763 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
NKCFMEJF_03764 1.2e-224 L DNA primase activity
NKCFMEJF_03765 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NKCFMEJF_03766 0.0 2.7.7.7 L DNA polymerase
NKCFMEJF_03767 9.9e-115 DR0488 S protein conserved in bacteria
NKCFMEJF_03772 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
NKCFMEJF_03773 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NKCFMEJF_03775 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
NKCFMEJF_03792 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NKCFMEJF_03793 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKCFMEJF_03794 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKCFMEJF_03795 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKCFMEJF_03796 3.3e-97 L HNH endonuclease
NKCFMEJF_03797 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NKCFMEJF_03798 6.1e-38 O Glutaredoxin
NKCFMEJF_03799 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NKCFMEJF_03800 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
NKCFMEJF_03805 2.5e-30 sspB S spore protein
NKCFMEJF_03806 1.9e-168 S Calcineurin-like phosphoesterase
NKCFMEJF_03814 1.4e-10 K Cro/C1-type HTH DNA-binding domain
NKCFMEJF_03815 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NKCFMEJF_03817 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
NKCFMEJF_03818 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NKCFMEJF_03819 3.3e-188 cgeB S Spore maturation protein
NKCFMEJF_03820 1.2e-65 cgeA
NKCFMEJF_03821 3.5e-38 cgeC
NKCFMEJF_03822 1e-256 cgeD M maturation of the outermost layer of the spore
NKCFMEJF_03823 2.9e-145 yiiD K acetyltransferase
NKCFMEJF_03826 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NKCFMEJF_03827 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NKCFMEJF_03828 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NKCFMEJF_03829 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NKCFMEJF_03830 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NKCFMEJF_03831 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NKCFMEJF_03832 2.9e-47 yokU S YokU-like protein, putative antitoxin
NKCFMEJF_03833 1.4e-36 yozE S Belongs to the UPF0346 family
NKCFMEJF_03834 1.4e-124 yodN
NKCFMEJF_03836 2.8e-24 yozD S YozD-like protein
NKCFMEJF_03837 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
NKCFMEJF_03838 3.6e-54 yodL S YodL-like
NKCFMEJF_03839 5.3e-09
NKCFMEJF_03840 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NKCFMEJF_03841 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NKCFMEJF_03842 5.2e-24 yodI
NKCFMEJF_03843 1.7e-128 yodH Q Methyltransferase
NKCFMEJF_03844 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NKCFMEJF_03845 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NKCFMEJF_03846 6.2e-28 S Protein of unknown function (DUF3311)
NKCFMEJF_03847 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
NKCFMEJF_03848 3.8e-113 mhqD S Carboxylesterase
NKCFMEJF_03849 4.8e-108 yodC C nitroreductase
NKCFMEJF_03850 1.7e-57 yodB K transcriptional
NKCFMEJF_03851 3.8e-66 yodA S tautomerase
NKCFMEJF_03852 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
NKCFMEJF_03853 3.4e-09
NKCFMEJF_03854 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
NKCFMEJF_03855 1.7e-149 rarD S -transporter
NKCFMEJF_03856 1.5e-43
NKCFMEJF_03857 2.2e-60 yojF S Protein of unknown function (DUF1806)
NKCFMEJF_03858 2.1e-125 yojG S deacetylase
NKCFMEJF_03859 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NKCFMEJF_03860 4.2e-245 norM V Multidrug efflux pump
NKCFMEJF_03862 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NKCFMEJF_03863 5.3e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NKCFMEJF_03864 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NKCFMEJF_03865 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NKCFMEJF_03866 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
NKCFMEJF_03867 0.0 yojO P Von Willebrand factor
NKCFMEJF_03868 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NKCFMEJF_03869 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NKCFMEJF_03870 5.1e-168 yocS S -transporter
NKCFMEJF_03871 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NKCFMEJF_03872 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
NKCFMEJF_03873 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NKCFMEJF_03874 1.1e-239 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NKCFMEJF_03875 1.6e-14 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NKCFMEJF_03876 2.7e-31 yozC
NKCFMEJF_03877 4.2e-56 yozO S Bacterial PH domain
NKCFMEJF_03878 1.9e-36 yocN
NKCFMEJF_03879 1.1e-40 yozN
NKCFMEJF_03880 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NKCFMEJF_03881 6.6e-34
NKCFMEJF_03882 6.4e-54 yocL
NKCFMEJF_03883 3.3e-83 dksA T general stress protein
NKCFMEJF_03884 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NKCFMEJF_03885 0.0 recQ 3.6.4.12 L DNA helicase
NKCFMEJF_03886 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NKCFMEJF_03887 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NKCFMEJF_03888 3.2e-198 desK 2.7.13.3 T Histidine kinase
NKCFMEJF_03889 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NKCFMEJF_03890 6.9e-189 yocD 3.4.17.13 V peptidase S66
NKCFMEJF_03891 1.9e-94 yocC
NKCFMEJF_03892 2.2e-145
NKCFMEJF_03893 1.5e-92 yozB S membrane
NKCFMEJF_03894 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NKCFMEJF_03895 1e-51 czrA K transcriptional
NKCFMEJF_03896 2.5e-95 yobW
NKCFMEJF_03897 9e-178 yobV K WYL domain
NKCFMEJF_03898 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
NKCFMEJF_03899 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NKCFMEJF_03900 3e-99 yobS K Transcriptional regulator
NKCFMEJF_03901 2.5e-143 yobR 2.3.1.1 J FR47-like protein
NKCFMEJF_03902 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
NKCFMEJF_03903 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NKCFMEJF_03904 0.0 yobO M Pectate lyase superfamily protein
NKCFMEJF_03905 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NKCFMEJF_03906 7.9e-105 yokH G SMI1 / KNR4 family
NKCFMEJF_03907 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NKCFMEJF_03908 3e-86 S SMI1-KNR4 cell-wall
NKCFMEJF_03909 2.7e-157 yobJ
NKCFMEJF_03910 0.0 K Psort location Cytoplasmic, score
NKCFMEJF_03911 1.2e-49
NKCFMEJF_03912 2.6e-38 S YolD-like protein
NKCFMEJF_03913 4.1e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKCFMEJF_03914 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NKCFMEJF_03916 1.7e-207 S aspartate phosphatase
NKCFMEJF_03921 1.8e-178 yobF
NKCFMEJF_03922 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
NKCFMEJF_03923 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
NKCFMEJF_03925 5.7e-58 K Helix-turn-helix
NKCFMEJF_03926 1.4e-37 S TM2 domain
NKCFMEJF_03927 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NKCFMEJF_03928 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NKCFMEJF_03932 2.3e-170 bla 3.5.2.6 V beta-lactamase
NKCFMEJF_03933 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NKCFMEJF_03934 3.7e-78 yoaW
NKCFMEJF_03935 6e-160 yijE EG EamA-like transporter family
NKCFMEJF_03936 8.6e-159 yoaU K LysR substrate binding domain
NKCFMEJF_03937 3.7e-87 yoaT S Protein of unknown function (DUF817)
NKCFMEJF_03938 5.2e-23 yoaT S Protein of unknown function (DUF817)
NKCFMEJF_03939 4.2e-37 yozG K Transcriptional regulator
NKCFMEJF_03940 4.3e-75 yoaS S Protein of unknown function (DUF2975)
NKCFMEJF_03941 2.4e-172 yoaR V vancomycin resistance protein
NKCFMEJF_03942 4.1e-89
NKCFMEJF_03943 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
NKCFMEJF_03944 1.5e-146 yoaP 3.1.3.18 K YoaP-like
NKCFMEJF_03946 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
NKCFMEJF_03948 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
NKCFMEJF_03949 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NKCFMEJF_03950 2.3e-111 yoaK S Membrane
NKCFMEJF_03951 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NKCFMEJF_03952 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NKCFMEJF_03953 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
NKCFMEJF_03954 1.5e-38 S Protein of unknown function (DUF4025)
NKCFMEJF_03955 7e-14
NKCFMEJF_03956 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
NKCFMEJF_03957 1.9e-33 yoaF
NKCFMEJF_03958 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NKCFMEJF_03959 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NKCFMEJF_03960 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NKCFMEJF_03961 6.2e-235 yoaB EGP Major facilitator Superfamily
NKCFMEJF_03962 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NKCFMEJF_03963 3.1e-144 yoxB
NKCFMEJF_03964 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
NKCFMEJF_03965 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NKCFMEJF_03966 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NKCFMEJF_03967 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NKCFMEJF_03968 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NKCFMEJF_03969 7.8e-155 gltC K Transcriptional regulator
NKCFMEJF_03970 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NKCFMEJF_03971 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NKCFMEJF_03972 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NKCFMEJF_03973 2.5e-158 gltR1 K Transcriptional regulator
NKCFMEJF_03974 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NKCFMEJF_03975 3e-34 yoeD G Helix-turn-helix domain
NKCFMEJF_03976 2.2e-96 L Integrase
NKCFMEJF_03978 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NKCFMEJF_03979 2.3e-246 yoeA V MATE efflux family protein
NKCFMEJF_03980 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
NKCFMEJF_03981 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NKCFMEJF_03982 2.9e-76 ctsR K Belongs to the CtsR family
NKCFMEJF_03983 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NKCFMEJF_03984 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NKCFMEJF_03985 0.0 clpC O Belongs to the ClpA ClpB family
NKCFMEJF_03986 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NKCFMEJF_03987 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NKCFMEJF_03988 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NKCFMEJF_03989 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NKCFMEJF_03990 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NKCFMEJF_03991 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NKCFMEJF_03992 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NKCFMEJF_03993 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NKCFMEJF_03994 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NKCFMEJF_03995 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NKCFMEJF_03996 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NKCFMEJF_03997 4.4e-115 sigH K Belongs to the sigma-70 factor family
NKCFMEJF_03998 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NKCFMEJF_03999 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NKCFMEJF_04000 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NKCFMEJF_04001 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NKCFMEJF_04002 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NKCFMEJF_04003 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NKCFMEJF_04004 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NKCFMEJF_04005 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKCFMEJF_04006 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKCFMEJF_04007 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NKCFMEJF_04008 1.9e-71 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NKCFMEJF_04009 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NKCFMEJF_04010 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NKCFMEJF_04011 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NKCFMEJF_04012 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NKCFMEJF_04013 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NKCFMEJF_04014 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NKCFMEJF_04015 3e-105 rplD J Forms part of the polypeptide exit tunnel
NKCFMEJF_04016 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NKCFMEJF_04017 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NKCFMEJF_04018 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NKCFMEJF_04019 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NKCFMEJF_04020 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NKCFMEJF_04021 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NKCFMEJF_04022 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NKCFMEJF_04023 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NKCFMEJF_04024 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NKCFMEJF_04025 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NKCFMEJF_04026 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NKCFMEJF_04027 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NKCFMEJF_04028 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NKCFMEJF_04029 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NKCFMEJF_04030 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NKCFMEJF_04031 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NKCFMEJF_04032 1.9e-23 rpmD J Ribosomal protein L30
NKCFMEJF_04033 1.8e-72 rplO J binds to the 23S rRNA
NKCFMEJF_04034 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NKCFMEJF_04035 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NKCFMEJF_04036 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NKCFMEJF_04037 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NKCFMEJF_04038 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NKCFMEJF_04039 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NKCFMEJF_04040 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NKCFMEJF_04041 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NKCFMEJF_04042 3.6e-58 rplQ J Ribosomal protein L17
NKCFMEJF_04043 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKCFMEJF_04044 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKCFMEJF_04045 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NKCFMEJF_04046 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NKCFMEJF_04047 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NKCFMEJF_04048 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NKCFMEJF_04049 6.9e-144 ybaJ Q Methyltransferase domain
NKCFMEJF_04050 9.7e-66 ybaK S Protein of unknown function (DUF2521)
NKCFMEJF_04051 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NKCFMEJF_04052 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NKCFMEJF_04053 1.2e-84 gerD
NKCFMEJF_04054 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NKCFMEJF_04055 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NKCFMEJF_04057 2.1e-193 xerH A Belongs to the 'phage' integrase family
NKCFMEJF_04058 6.3e-70
NKCFMEJF_04059 2.5e-86
NKCFMEJF_04060 2.5e-10 xkdX
NKCFMEJF_04061 8.1e-07
NKCFMEJF_04062 1.1e-172
NKCFMEJF_04063 1e-57
NKCFMEJF_04066 1.6e-90
NKCFMEJF_04067 8.1e-131
NKCFMEJF_04068 2.6e-91
NKCFMEJF_04069 1.4e-121
NKCFMEJF_04071 1.1e-68
NKCFMEJF_04072 5.1e-81
NKCFMEJF_04073 5.7e-186
NKCFMEJF_04074 1.6e-94
NKCFMEJF_04075 2.1e-266
NKCFMEJF_04076 6.3e-282
NKCFMEJF_04077 0.0 gp17a S Terminase-like family
NKCFMEJF_04078 1.8e-175
NKCFMEJF_04081 2.6e-230
NKCFMEJF_04083 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NKCFMEJF_04084 0.0
NKCFMEJF_04087 5.7e-55 bldD K domain, Protein
NKCFMEJF_04088 4e-17
NKCFMEJF_04090 5.9e-238
NKCFMEJF_04092 1.4e-256
NKCFMEJF_04093 4.6e-35 K Cro/C1-type HTH DNA-binding domain
NKCFMEJF_04094 3.8e-259
NKCFMEJF_04095 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
NKCFMEJF_04100 1.1e-96 S Super-infection exclusion protein B
NKCFMEJF_04101 1.2e-86
NKCFMEJF_04103 6.6e-106
NKCFMEJF_04108 6.8e-198 L Belongs to the 'phage' integrase family
NKCFMEJF_04109 6e-263 S DNA-sulfur modification-associated
NKCFMEJF_04110 2.1e-177
NKCFMEJF_04111 1.1e-33 K Transcriptional regulator
NKCFMEJF_04122 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
NKCFMEJF_04123 8.8e-12 S Protein of unknown function (DUF2815)
NKCFMEJF_04126 3e-78 yoqH M LysM domain
NKCFMEJF_04128 1.5e-97 S Protein of unknown function (DUF1273)
NKCFMEJF_04130 1e-44
NKCFMEJF_04137 2.3e-77
NKCFMEJF_04138 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
NKCFMEJF_04139 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
NKCFMEJF_04142 1.1e-147 S Pfam:DUF867
NKCFMEJF_04143 3.4e-31 csfB S Inhibitor of sigma-G Gin
NKCFMEJF_04144 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NKCFMEJF_04145 4.5e-203 yaaN P Belongs to the TelA family
NKCFMEJF_04146 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NKCFMEJF_04147 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NKCFMEJF_04148 2.2e-54 yaaQ S protein conserved in bacteria
NKCFMEJF_04149 1.5e-71 yaaR S protein conserved in bacteria
NKCFMEJF_04150 2.2e-182 holB 2.7.7.7 L DNA polymerase III
NKCFMEJF_04151 2.1e-146 yaaT S stage 0 sporulation protein
NKCFMEJF_04152 4.8e-31 yabA L Involved in initiation control of chromosome replication
NKCFMEJF_04153 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NKCFMEJF_04154 1.5e-49 yazA L endonuclease containing a URI domain
NKCFMEJF_04155 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NKCFMEJF_04156 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NKCFMEJF_04157 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NKCFMEJF_04158 1.8e-144 tatD L hydrolase, TatD
NKCFMEJF_04159 4.3e-194 rpfB GH23 T protein conserved in bacteria
NKCFMEJF_04160 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NKCFMEJF_04161 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NKCFMEJF_04162 3.3e-137 yabG S peptidase
NKCFMEJF_04163 7.8e-39 veg S protein conserved in bacteria
NKCFMEJF_04164 8.3e-27 sspF S DNA topological change
NKCFMEJF_04165 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NKCFMEJF_04166 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NKCFMEJF_04167 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NKCFMEJF_04168 1e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NKCFMEJF_04169 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NKCFMEJF_04170 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NKCFMEJF_04171 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NKCFMEJF_04172 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NKCFMEJF_04173 2.4e-39 yabK S Peptide ABC transporter permease
NKCFMEJF_04174 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NKCFMEJF_04175 1.5e-92 spoVT K stage V sporulation protein
NKCFMEJF_04176 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NKCFMEJF_04177 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NKCFMEJF_04178 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NKCFMEJF_04179 1.5e-49 yabP S Sporulation protein YabP
NKCFMEJF_04180 3.9e-108 yabQ S spore cortex biosynthesis protein
NKCFMEJF_04181 1.1e-44 divIC D Septum formation initiator
NKCFMEJF_04182 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NKCFMEJF_04185 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NKCFMEJF_04186 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NKCFMEJF_04187 6.7e-187 KLT serine threonine protein kinase
NKCFMEJF_04188 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NKCFMEJF_04189 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NKCFMEJF_04190 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NKCFMEJF_04191 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NKCFMEJF_04192 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NKCFMEJF_04193 1.6e-160 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NKCFMEJF_04194 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NKCFMEJF_04195 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NKCFMEJF_04196 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NKCFMEJF_04197 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NKCFMEJF_04198 9.4e-46 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NKCFMEJF_04199 1.5e-94 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NKCFMEJF_04200 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NKCFMEJF_04201 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NKCFMEJF_04202 4.1e-30 yazB K transcriptional
NKCFMEJF_04203 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NKCFMEJF_04204 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NKCFMEJF_04205 3.4e-39 S COG NOG14552 non supervised orthologous group
NKCFMEJF_04207 2.6e-242 mmr U Major Facilitator Superfamily
NKCFMEJF_04208 2.8e-79 yffB K Transcriptional regulator
NKCFMEJF_04209 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NKCFMEJF_04210 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
NKCFMEJF_04211 3.1e-36 ywzC S Belongs to the UPF0741 family
NKCFMEJF_04212 1.6e-111 rsfA_1
NKCFMEJF_04213 5.2e-159 ywfM EG EamA-like transporter family
NKCFMEJF_04214 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NKCFMEJF_04215 9.2e-164 cysL K Transcriptional regulator
NKCFMEJF_04216 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NKCFMEJF_04217 1.1e-146 ywfI C May function as heme-dependent peroxidase
NKCFMEJF_04218 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
NKCFMEJF_04219 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
NKCFMEJF_04220 2.9e-210 bacE EGP Major facilitator Superfamily
NKCFMEJF_04221 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NKCFMEJF_04222 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NKCFMEJF_04223 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NKCFMEJF_04224 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NKCFMEJF_04225 4.6e-206 ywfA EGP Major facilitator Superfamily
NKCFMEJF_04226 5.1e-251 lysP E amino acid
NKCFMEJF_04227 0.0 rocB E arginine degradation protein
NKCFMEJF_04228 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NKCFMEJF_04229 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NKCFMEJF_04230 1.8e-78
NKCFMEJF_04231 3.5e-87 spsL 5.1.3.13 M Spore Coat
NKCFMEJF_04232 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_04233 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_04234 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
NKCFMEJF_04235 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NKCFMEJF_04236 6e-55 ypuD
NKCFMEJF_04237 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NKCFMEJF_04238 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NKCFMEJF_04239 1.5e-17 S SNARE associated Golgi protein
NKCFMEJF_04242 9.8e-15
NKCFMEJF_04243 1.4e-138
NKCFMEJF_04244 5.5e-103 GH23 M Transglycosylase SLT domain
NKCFMEJF_04245 7e-90
NKCFMEJF_04246 8.6e-59
NKCFMEJF_04247 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_04248 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NKCFMEJF_04249 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NKCFMEJF_04250 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NKCFMEJF_04251 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NKCFMEJF_04252 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NKCFMEJF_04253 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NKCFMEJF_04254 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
NKCFMEJF_04255 3.7e-194 yaaH M Glycoside Hydrolase Family
NKCFMEJF_04256 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NKCFMEJF_04257 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NKCFMEJF_04258 1.3e-09
NKCFMEJF_04259 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NKCFMEJF_04260 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NKCFMEJF_04261 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NKCFMEJF_04262 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NKCFMEJF_04263 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NKCFMEJF_04264 2.7e-182 yaaC S YaaC-like Protein
NKCFMEJF_04265 7.6e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NKCFMEJF_04266 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NKCFMEJF_04267 1.9e-11 ypuI S Protein of unknown function (DUF3907)
NKCFMEJF_04268 9.4e-88
NKCFMEJF_04269 1.4e-62
NKCFMEJF_04270 9.1e-33 MU LPXTG cell wall anchor motif
NKCFMEJF_04271 1.2e-29 K Helix-turn-helix XRE-family like proteins
NKCFMEJF_04272 3e-284 repE K Primase C terminal 1 (PriCT-1)
NKCFMEJF_04274 4.3e-96 tnpR L Resolvase, N terminal domain
NKCFMEJF_04275 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_04276 3.3e-83 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_04277 5.1e-131 traI 5.99.1.2 L Bacterial DNA topoisomeraes I ATP-binding domain
NKCFMEJF_04278 1.3e-162 D sporulation initiation inhibitor
NKCFMEJF_04279 2.8e-31 S Omega Transcriptional Repressor
NKCFMEJF_04280 1.2e-34 S Bacterial epsilon antitoxin
NKCFMEJF_04281 2.6e-147 2.7.1.176 S Zeta toxin
NKCFMEJF_04282 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NKCFMEJF_04283 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NKCFMEJF_04284 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKCFMEJF_04285 4.5e-94 ypuF S Domain of unknown function (DUF309)
NKCFMEJF_04286 5.9e-160 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NKCFMEJF_04287 5.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NKCFMEJF_04288 1.1e-62 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NKCFMEJF_04289 6.2e-88 ypuF S Domain of unknown function (DUF309)
NKCFMEJF_04291 1.6e-160 penP 3.5.2.6 V beta-lactamase
NKCFMEJF_04292 2.6e-14 ypuD
NKCFMEJF_04293 6.2e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NKCFMEJF_04294 7.2e-110 ribE 2.5.1.9 H Riboflavin synthase
NKCFMEJF_04295 3.6e-29 S Plasmid replication protein
NKCFMEJF_04296 1.2e-242 tetL EGP Major Facilitator Superfamily
NKCFMEJF_04297 1.8e-34 L Replication protein
NKCFMEJF_04298 1.6e-81 S KNTase C-terminal domain
NKCFMEJF_04299 1.3e-57 ble E Glyoxalase-like domain
NKCFMEJF_04300 1.6e-134 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
NKCFMEJF_04301 3.1e-125 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NKCFMEJF_04302 2.2e-96 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NKCFMEJF_04307 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)