ORF_ID e_value Gene_name EC_number CAZy COGs Description
MDJIHKML_00001 1.3e-246 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDJIHKML_00002 3.8e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDJIHKML_00003 5.9e-35 yaaA S S4 domain protein YaaA
MDJIHKML_00004 1.3e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDJIHKML_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDJIHKML_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDJIHKML_00007 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
MDJIHKML_00008 2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDJIHKML_00009 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDJIHKML_00010 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MDJIHKML_00011 2.1e-71 rplI J Binds to the 23S rRNA
MDJIHKML_00012 5.5e-256 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MDJIHKML_00013 1.1e-172 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
MDJIHKML_00014 8.3e-176 degV S DegV family
MDJIHKML_00015 1.6e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MDJIHKML_00016 1e-16 S CsbD-like
MDJIHKML_00017 1e-30
MDJIHKML_00018 1.2e-238 I Protein of unknown function (DUF2974)
MDJIHKML_00020 6.7e-97 cadD P Cadmium resistance transporter
MDJIHKML_00021 1.6e-58 cadX K helix_turn_helix, Arsenical Resistance Operon Repressor
MDJIHKML_00022 5e-184
MDJIHKML_00023 4.6e-54
MDJIHKML_00024 1.1e-206 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDJIHKML_00025 8.6e-93
MDJIHKML_00026 4.9e-184 repB EP Plasmid replication protein
MDJIHKML_00027 1.5e-31
MDJIHKML_00028 4e-234 L Belongs to the 'phage' integrase family
MDJIHKML_00029 1.3e-31
MDJIHKML_00030 6.5e-69 doc S Fic/DOC family
MDJIHKML_00031 5.3e-20 S Protein of unknown function (DUF3923)
MDJIHKML_00034 3.9e-161 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
MDJIHKML_00035 2.3e-278 pipD E Dipeptidase
MDJIHKML_00036 1.3e-230 S LPXTG cell wall anchor motif
MDJIHKML_00037 3.6e-151 S Putative ABC-transporter type IV
MDJIHKML_00038 7.7e-100 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
MDJIHKML_00039 4.5e-86 S ECF transporter, substrate-specific component
MDJIHKML_00040 5.9e-54 S Domain of unknown function (DUF4430)
MDJIHKML_00041 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
MDJIHKML_00042 7.1e-176 K AI-2E family transporter
MDJIHKML_00043 3.6e-105 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
MDJIHKML_00044 5.5e-15
MDJIHKML_00045 7.6e-247 G Major Facilitator
MDJIHKML_00046 1.7e-52
MDJIHKML_00047 2.6e-135 XK27_08845 S ABC transporter, ATP-binding protein
MDJIHKML_00048 2.6e-126 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MDJIHKML_00049 1.5e-178 ABC-SBP S ABC transporter
MDJIHKML_00050 4e-138 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MDJIHKML_00051 0.0 tetP J elongation factor G
MDJIHKML_00052 1.3e-151 3.1.3.102, 3.1.3.104 S hydrolase
MDJIHKML_00053 6.5e-30 S endonuclease exonuclease phosphatase family protein
MDJIHKML_00054 2.7e-134 S endonuclease exonuclease phosphatase family protein
MDJIHKML_00055 2.8e-15 S endonuclease exonuclease phosphatase family protein
MDJIHKML_00056 1.4e-192 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDJIHKML_00057 1.8e-153 xth 3.1.11.2 L exodeoxyribonuclease III
MDJIHKML_00058 1e-273 E amino acid
MDJIHKML_00059 0.0 L Helicase C-terminal domain protein
MDJIHKML_00060 2.9e-215 pbpX1 V Beta-lactamase
MDJIHKML_00061 3.2e-71 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDJIHKML_00063 2.2e-51 K LysR substrate binding domain
MDJIHKML_00064 4.2e-56 1.3.5.4 S FMN_bind
MDJIHKML_00065 2.6e-230 1.3.5.4 C FAD binding domain
MDJIHKML_00066 5.6e-115 K Transcriptional regulator, LysR family
MDJIHKML_00067 1.5e-38 S Cytochrome B5
MDJIHKML_00068 5e-167 arbZ I Phosphate acyltransferases
MDJIHKML_00069 8.4e-184 arbY M Glycosyl transferase family 8
MDJIHKML_00070 2.2e-187 arbY M Glycosyl transferase family 8
MDJIHKML_00071 1.1e-158 arbx M Glycosyl transferase family 8
MDJIHKML_00072 2.1e-148 arbV 2.3.1.51 I Acyl-transferase
MDJIHKML_00073 3e-78
MDJIHKML_00074 2.8e-288 P ABC transporter
MDJIHKML_00075 1.4e-295 V ABC-type multidrug transport system, ATPase and permease components
MDJIHKML_00076 0.0 L Transposase
MDJIHKML_00079 9.7e-132 K response regulator
MDJIHKML_00080 5.3e-307 vicK 2.7.13.3 T Histidine kinase
MDJIHKML_00081 1e-259 yycH S YycH protein
MDJIHKML_00082 9.4e-147 yycI S YycH protein
MDJIHKML_00083 1.1e-149 vicX 3.1.26.11 S domain protein
MDJIHKML_00084 8.8e-149 htrA 3.4.21.107 O serine protease
MDJIHKML_00085 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDJIHKML_00086 2.4e-150 K Helix-turn-helix XRE-family like proteins
MDJIHKML_00088 2.1e-258 S CAAX protease self-immunity
MDJIHKML_00089 4.5e-18
MDJIHKML_00090 1.1e-121
MDJIHKML_00091 1.3e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
MDJIHKML_00092 8.9e-92 P Cobalt transport protein
MDJIHKML_00093 6e-252 cbiO1 S ABC transporter, ATP-binding protein
MDJIHKML_00094 3.9e-173 K helix_turn_helix, arabinose operon control protein
MDJIHKML_00095 1.6e-163 htpX O Belongs to the peptidase M48B family
MDJIHKML_00096 1.4e-93 lemA S LemA family
MDJIHKML_00097 2.5e-195 ybiR P Citrate transporter
MDJIHKML_00098 2.2e-69 S Iron-sulphur cluster biosynthesis
MDJIHKML_00099 1.1e-301 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
MDJIHKML_00100 1.2e-17
MDJIHKML_00101 1.6e-152
MDJIHKML_00103 1.6e-228 ydaM M Glycosyl transferase family group 2
MDJIHKML_00104 1.5e-211 G Glycosyl hydrolases family 8
MDJIHKML_00105 3.7e-122 yfbR S HD containing hydrolase-like enzyme
MDJIHKML_00106 4e-161 L HNH nucleases
MDJIHKML_00107 1.2e-182 S Protein of unknown function (DUF805)
MDJIHKML_00108 2.1e-137 glnQ E ABC transporter, ATP-binding protein
MDJIHKML_00109 1e-293 glnP P ABC transporter permease
MDJIHKML_00110 5.5e-123 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MDJIHKML_00111 2.5e-64 yeaO S Protein of unknown function, DUF488
MDJIHKML_00112 5.8e-138 terC P Integral membrane protein TerC family
MDJIHKML_00113 2.3e-133 cobB K SIR2 family
MDJIHKML_00114 1.7e-84
MDJIHKML_00115 1.2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDJIHKML_00116 1.9e-180 S Alpha/beta hydrolase of unknown function (DUF915)
MDJIHKML_00117 2.2e-142 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDJIHKML_00118 7.7e-137 ypuA S Protein of unknown function (DUF1002)
MDJIHKML_00119 7.3e-160 2.4.1.293 GT2 M Glycosyltransferase like family 2
MDJIHKML_00120 5.6e-126 S Alpha/beta hydrolase family
MDJIHKML_00121 8.3e-148 K Helix-turn-helix XRE-family like proteins
MDJIHKML_00122 2.9e-51
MDJIHKML_00123 1.2e-263 L COG2963 Transposase and inactivated derivatives
MDJIHKML_00124 4.1e-46
MDJIHKML_00125 3.3e-43 3.6.4.12
MDJIHKML_00126 1.6e-76 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MDJIHKML_00127 2e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDJIHKML_00128 2.2e-125 luxT K Bacterial regulatory proteins, tetR family
MDJIHKML_00129 2.1e-130
MDJIHKML_00130 1.4e-257 glnPH2 P ABC transporter permease
MDJIHKML_00131 1.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDJIHKML_00132 6.6e-229 S Cysteine-rich secretory protein family
MDJIHKML_00133 4.7e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MDJIHKML_00134 7.2e-90
MDJIHKML_00135 4.4e-203 yibE S overlaps another CDS with the same product name
MDJIHKML_00136 2.4e-131 yibF S overlaps another CDS with the same product name
MDJIHKML_00137 5.6e-160 I alpha/beta hydrolase fold
MDJIHKML_00138 0.0 G Belongs to the glycosyl hydrolase 31 family
MDJIHKML_00139 5.2e-228 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDJIHKML_00140 1.8e-89 ntd 2.4.2.6 F Nucleoside
MDJIHKML_00141 1.1e-86 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDJIHKML_00142 2.2e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
MDJIHKML_00143 1.6e-85 uspA T universal stress protein
MDJIHKML_00144 1.5e-164 phnD P Phosphonate ABC transporter
MDJIHKML_00145 2.3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MDJIHKML_00146 2.8e-132 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MDJIHKML_00147 7.6e-149 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MDJIHKML_00148 8.6e-107 tag 3.2.2.20 L glycosylase
MDJIHKML_00149 1.5e-83
MDJIHKML_00150 3.4e-274 S Calcineurin-like phosphoesterase
MDJIHKML_00151 0.0 asnB 6.3.5.4 E Asparagine synthase
MDJIHKML_00152 3.3e-252 yxbA 6.3.1.12 S ATP-grasp enzyme
MDJIHKML_00153 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MDJIHKML_00154 8.1e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDJIHKML_00155 6.5e-99 S Iron-sulfur cluster assembly protein
MDJIHKML_00156 1.1e-233 XK27_04775 S PAS domain
MDJIHKML_00157 1.1e-228 yttB EGP Major facilitator Superfamily
MDJIHKML_00158 0.0 pepO 3.4.24.71 O Peptidase family M13
MDJIHKML_00159 0.0 kup P Transport of potassium into the cell
MDJIHKML_00160 1.9e-69
MDJIHKML_00161 6.9e-11
MDJIHKML_00162 7.9e-212 S SLAP domain
MDJIHKML_00163 3e-60 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MDJIHKML_00164 2.4e-256 ica2 GT2 M Glycosyl transferase family group 2
MDJIHKML_00165 2.2e-175
MDJIHKML_00166 2.1e-228 S SLAP domain
MDJIHKML_00167 1.1e-207 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDJIHKML_00168 7.2e-211 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
MDJIHKML_00169 0.0 yjbQ P TrkA C-terminal domain protein
MDJIHKML_00170 9.8e-180 S Oxidoreductase family, NAD-binding Rossmann fold
MDJIHKML_00171 7.4e-141
MDJIHKML_00172 1.5e-135
MDJIHKML_00173 2.5e-132 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDJIHKML_00174 1.8e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDJIHKML_00175 1.6e-102 G Aldose 1-epimerase
MDJIHKML_00176 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDJIHKML_00177 6.4e-108 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDJIHKML_00178 0.0 XK27_08315 M Sulfatase
MDJIHKML_00179 6.2e-268 S Fibronectin type III domain
MDJIHKML_00180 3.3e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDJIHKML_00181 3.3e-56
MDJIHKML_00183 7.2e-258 pepC 3.4.22.40 E aminopeptidase
MDJIHKML_00184 1.2e-125 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDJIHKML_00185 5e-293 oppA E ABC transporter, substratebinding protein
MDJIHKML_00186 4.6e-307 oppA E ABC transporter, substratebinding protein
MDJIHKML_00187 7.5e-211 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDJIHKML_00188 1.1e-143 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDJIHKML_00189 4e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDJIHKML_00190 2.2e-201 oppD P Belongs to the ABC transporter superfamily
MDJIHKML_00191 1.9e-175 oppF P Belongs to the ABC transporter superfamily
MDJIHKML_00192 2.3e-256 pepC 3.4.22.40 E aminopeptidase
MDJIHKML_00193 2.4e-69 hsp O Belongs to the small heat shock protein (HSP20) family
MDJIHKML_00194 8.8e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDJIHKML_00195 1.3e-114
MDJIHKML_00197 4.2e-112 E Belongs to the SOS response-associated peptidase family
MDJIHKML_00198 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDJIHKML_00199 6.5e-92 comEB 3.5.4.12 F MafB19-like deaminase
MDJIHKML_00200 3.4e-109 S TPM domain
MDJIHKML_00201 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
MDJIHKML_00202 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDJIHKML_00203 3.5e-148 tatD L hydrolase, TatD family
MDJIHKML_00204 1.6e-92 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDJIHKML_00205 1.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDJIHKML_00206 3.5e-39 veg S Biofilm formation stimulator VEG
MDJIHKML_00207 1.6e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MDJIHKML_00208 1.4e-211 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDJIHKML_00209 9.6e-89 S SLAP domain
MDJIHKML_00210 8.4e-90 S SLAP domain
MDJIHKML_00211 1.5e-86
MDJIHKML_00212 7.3e-239 S SLAP domain
MDJIHKML_00213 1.6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDJIHKML_00214 5.2e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDJIHKML_00215 7.7e-129 K Helix-turn-helix domain, rpiR family
MDJIHKML_00216 1.2e-231 ptcC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDJIHKML_00217 3.3e-169 2.7.1.2 GK ROK family
MDJIHKML_00218 3.9e-44
MDJIHKML_00219 7.2e-269 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDJIHKML_00220 9.5e-68 S Domain of unknown function (DUF1934)
MDJIHKML_00221 3.3e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDJIHKML_00222 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDJIHKML_00223 1.8e-245 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDJIHKML_00224 1.9e-109 pipD E Dipeptidase
MDJIHKML_00225 4.4e-160 pipD E Dipeptidase
MDJIHKML_00226 7.4e-160 msmR K AraC-like ligand binding domain
MDJIHKML_00227 7e-107 S Protein of unknown function (DUF1211)
MDJIHKML_00228 5.2e-221 pbuX F xanthine permease
MDJIHKML_00229 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDJIHKML_00230 1.5e-135 K DNA-binding helix-turn-helix protein
MDJIHKML_00231 7.5e-172 K Helix-turn-helix
MDJIHKML_00232 6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MDJIHKML_00233 2.5e-155 cylA V ABC transporter
MDJIHKML_00234 4e-148 cylB V ABC-2 type transporter
MDJIHKML_00235 1.3e-73 K LytTr DNA-binding domain
MDJIHKML_00236 2.7e-43 S Protein of unknown function (DUF3021)
MDJIHKML_00237 1.9e-89 XK27_09675 K Acetyltransferase (GNAT) domain
MDJIHKML_00238 7e-135 S B3 4 domain
MDJIHKML_00239 5.4e-90 lmrB P Belongs to the major facilitator superfamily
MDJIHKML_00240 1.6e-32 P Belongs to the major facilitator superfamily
MDJIHKML_00241 1.9e-30
MDJIHKML_00242 7.7e-82 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDJIHKML_00243 2.5e-28 K NAD+ binding
MDJIHKML_00245 2.1e-96
MDJIHKML_00246 3.7e-51
MDJIHKML_00247 6.7e-44
MDJIHKML_00248 1.3e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDJIHKML_00249 1.1e-300 ybeC E amino acid
MDJIHKML_00250 3.7e-159 G Sucrose-6F-phosphate phosphohydrolase
MDJIHKML_00251 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
MDJIHKML_00252 1.9e-39 rpmE2 J Ribosomal protein L31
MDJIHKML_00253 7.7e-263 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDJIHKML_00254 3.9e-252 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDJIHKML_00255 7.6e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDJIHKML_00256 1.4e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDJIHKML_00257 5.8e-129 S (CBS) domain
MDJIHKML_00258 2.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDJIHKML_00259 1.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDJIHKML_00260 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDJIHKML_00261 2.4e-34 yabO J S4 domain protein
MDJIHKML_00262 1.1e-57 divIC D Septum formation initiator
MDJIHKML_00263 2.8e-63 yabR J S1 RNA binding domain
MDJIHKML_00264 2.2e-240 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDJIHKML_00265 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDJIHKML_00266 2.6e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDJIHKML_00267 1.4e-195 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDJIHKML_00268 1.5e-302 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MDJIHKML_00269 7.8e-08
MDJIHKML_00270 7.8e-08
MDJIHKML_00272 4.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
MDJIHKML_00273 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDJIHKML_00274 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDJIHKML_00275 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDJIHKML_00276 7.9e-123 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MDJIHKML_00277 1.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDJIHKML_00278 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDJIHKML_00279 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDJIHKML_00280 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MDJIHKML_00281 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDJIHKML_00282 4.6e-106 rplD J Forms part of the polypeptide exit tunnel
MDJIHKML_00283 1.2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDJIHKML_00284 4.3e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDJIHKML_00285 9.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDJIHKML_00286 3.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDJIHKML_00287 4.9e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDJIHKML_00288 6e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDJIHKML_00289 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MDJIHKML_00290 3.8e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDJIHKML_00291 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDJIHKML_00292 4.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDJIHKML_00293 7.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDJIHKML_00294 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDJIHKML_00295 9.3e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDJIHKML_00296 2.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDJIHKML_00297 2.1e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDJIHKML_00298 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDJIHKML_00299 2.3e-24 rpmD J Ribosomal protein L30
MDJIHKML_00300 2e-71 rplO J Binds to the 23S rRNA
MDJIHKML_00301 4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDJIHKML_00302 2e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDJIHKML_00303 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDJIHKML_00304 2.7e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MDJIHKML_00305 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDJIHKML_00306 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDJIHKML_00307 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDJIHKML_00308 8.2e-61 rplQ J Ribosomal protein L17
MDJIHKML_00309 2.8e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDJIHKML_00310 2.4e-161 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDJIHKML_00311 9.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDJIHKML_00312 3e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDJIHKML_00313 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDJIHKML_00314 3.5e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
MDJIHKML_00315 1e-198 L Phage integrase family
MDJIHKML_00316 6.5e-27
MDJIHKML_00317 5.5e-211 repB EP Plasmid replication protein
MDJIHKML_00318 6.6e-45
MDJIHKML_00319 3.1e-206 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDJIHKML_00320 1.1e-52
MDJIHKML_00322 0.0 V Type II restriction enzyme, methylase subunits
MDJIHKML_00323 6.9e-65 S YjcQ protein
MDJIHKML_00324 1.7e-13
MDJIHKML_00325 2.8e-11
MDJIHKML_00326 2.5e-109 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MDJIHKML_00327 2.5e-118 3.1.3.102, 3.1.3.104, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MDJIHKML_00328 5.8e-111 S membrane transporter protein
MDJIHKML_00329 4.7e-128 pgm3 5.4.2.11 G Belongs to the phosphoglycerate mutase family
MDJIHKML_00330 2.1e-163 czcD P cation diffusion facilitator family transporter
MDJIHKML_00331 2.2e-19
MDJIHKML_00332 2.4e-80 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDJIHKML_00333 6.4e-184 S AAA domain
MDJIHKML_00334 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
MDJIHKML_00335 7e-52
MDJIHKML_00336 9.5e-103 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MDJIHKML_00337 9.2e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDJIHKML_00338 9.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDJIHKML_00339 6.8e-278 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDJIHKML_00340 2.3e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDJIHKML_00341 1.6e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDJIHKML_00342 3.5e-94 sigH K Belongs to the sigma-70 factor family
MDJIHKML_00343 2.2e-34
MDJIHKML_00344 3.5e-114
MDJIHKML_00345 3.7e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MDJIHKML_00346 8.1e-173 K helix_turn_helix, arabinose operon control protein
MDJIHKML_00347 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDJIHKML_00348 7.8e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDJIHKML_00349 6.2e-102 nusG K Participates in transcription elongation, termination and antitermination
MDJIHKML_00350 6.9e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDJIHKML_00351 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDJIHKML_00352 1.5e-158 pstS P Phosphate
MDJIHKML_00353 5.2e-176 pstC P probably responsible for the translocation of the substrate across the membrane
MDJIHKML_00354 2.6e-155 pstA P Phosphate transport system permease protein PstA
MDJIHKML_00355 4.2e-144 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDJIHKML_00356 7e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDJIHKML_00357 2e-118 phoU P Plays a role in the regulation of phosphate uptake
MDJIHKML_00358 2.2e-210 yfdV S Membrane transport protein
MDJIHKML_00359 2.2e-10
MDJIHKML_00360 1.6e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDJIHKML_00361 2.2e-47 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDJIHKML_00362 1.5e-123 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
MDJIHKML_00363 6.4e-116 rsmC 2.1.1.172 J Methyltransferase
MDJIHKML_00364 1.4e-23
MDJIHKML_00365 6.9e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDJIHKML_00366 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDJIHKML_00367 3.5e-224 tnpB L Putative transposase DNA-binding domain
MDJIHKML_00368 2e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDJIHKML_00369 3.7e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDJIHKML_00370 1.1e-34 S Protein of unknown function (DUF2508)
MDJIHKML_00371 2.3e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDJIHKML_00372 5.8e-52 yaaQ S Cyclic-di-AMP receptor
MDJIHKML_00373 2.6e-155 holB 2.7.7.7 L DNA polymerase III
MDJIHKML_00374 3e-60 yabA L Involved in initiation control of chromosome replication
MDJIHKML_00375 6.7e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDJIHKML_00376 9.6e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
MDJIHKML_00377 5.2e-87 S ECF transporter, substrate-specific component
MDJIHKML_00378 1.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MDJIHKML_00379 3.3e-106 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MDJIHKML_00380 1.1e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDJIHKML_00381 1.3e-131 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MDJIHKML_00382 2.1e-182 S Oxidoreductase family, NAD-binding Rossmann fold
MDJIHKML_00383 4.9e-128 yegW K UTRA
MDJIHKML_00384 6.5e-234 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDJIHKML_00385 4.3e-266 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDJIHKML_00386 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MDJIHKML_00387 0.0 uup S ABC transporter, ATP-binding protein
MDJIHKML_00388 1.3e-111 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDJIHKML_00389 1e-184 scrR K helix_turn _helix lactose operon repressor
MDJIHKML_00390 5.6e-296 scrB 3.2.1.26 GH32 G invertase
MDJIHKML_00391 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
MDJIHKML_00392 5.8e-75
MDJIHKML_00393 1.1e-77 XK27_02470 K LytTr DNA-binding domain
MDJIHKML_00394 6.9e-128 liaI S membrane
MDJIHKML_00395 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDJIHKML_00396 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDJIHKML_00397 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDJIHKML_00398 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDJIHKML_00399 2.7e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDJIHKML_00400 4.6e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDJIHKML_00401 1.1e-47 yajC U Preprotein translocase
MDJIHKML_00402 5.3e-286 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDJIHKML_00403 2.2e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDJIHKML_00404 6.1e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MDJIHKML_00405 3.3e-229 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDJIHKML_00406 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDJIHKML_00407 2e-42 yrzL S Belongs to the UPF0297 family
MDJIHKML_00408 2.7e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDJIHKML_00409 2.8e-51 yrzB S Belongs to the UPF0473 family
MDJIHKML_00410 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDJIHKML_00411 6e-54 trxA O Belongs to the thioredoxin family
MDJIHKML_00412 4e-36 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDJIHKML_00413 2.3e-69 yslB S Protein of unknown function (DUF2507)
MDJIHKML_00414 3.8e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MDJIHKML_00415 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDJIHKML_00416 8.2e-130 ykuT M mechanosensitive ion channel
MDJIHKML_00417 3.6e-09 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDJIHKML_00418 2.1e-45
MDJIHKML_00419 7.5e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MDJIHKML_00420 2.9e-182 ccpA K catabolite control protein A
MDJIHKML_00421 3.9e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MDJIHKML_00422 1.9e-55
MDJIHKML_00423 5.2e-275 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MDJIHKML_00424 1.3e-81 yutD S Protein of unknown function (DUF1027)
MDJIHKML_00425 7.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDJIHKML_00426 1.1e-107 S Protein of unknown function (DUF1461)
MDJIHKML_00427 2.3e-116 dedA S SNARE-like domain protein
MDJIHKML_00428 1.1e-150 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MDJIHKML_00447 7.1e-74 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
MDJIHKML_00448 0.0 L Helicase C-terminal domain protein
MDJIHKML_00449 1.6e-45 L Helicase C-terminal domain protein
MDJIHKML_00461 2.3e-223 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
MDJIHKML_00462 2.9e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
MDJIHKML_00463 4.7e-180 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDJIHKML_00464 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDJIHKML_00465 7.5e-25 secG U Preprotein translocase
MDJIHKML_00466 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDJIHKML_00467 7.4e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDJIHKML_00469 4.2e-189 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MDJIHKML_00470 2.5e-136 manY G PTS system
MDJIHKML_00471 6.3e-176 manN G system, mannose fructose sorbose family IID component
MDJIHKML_00472 4e-65 manO S Domain of unknown function (DUF956)
MDJIHKML_00473 3.7e-160 K Transcriptional regulator
MDJIHKML_00474 3.9e-69 S transferase hexapeptide repeat
MDJIHKML_00475 9.2e-248 cycA E Amino acid permease
MDJIHKML_00476 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MDJIHKML_00477 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDJIHKML_00478 7.3e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDJIHKML_00479 1.3e-136 4.1.1.44 S Carboxymuconolactone decarboxylase family
MDJIHKML_00480 2.1e-70 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MDJIHKML_00481 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MDJIHKML_00482 0.0 S TerB-C domain
MDJIHKML_00483 1.4e-253 P P-loop Domain of unknown function (DUF2791)
MDJIHKML_00484 0.0 lhr L DEAD DEAH box helicase
MDJIHKML_00485 4.3e-62
MDJIHKML_00486 7.1e-231 amtB P ammonium transporter
MDJIHKML_00487 6.8e-144 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MDJIHKML_00489 0.0 L Type III restriction enzyme, res subunit
MDJIHKML_00490 0.0 S AAA ATPase domain
MDJIHKML_00491 3.4e-163 dam2 2.1.1.72 L DNA methyltransferase
MDJIHKML_00492 7.1e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
MDJIHKML_00494 6.3e-57
MDJIHKML_00495 1.9e-211 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDJIHKML_00497 7.7e-186 repB EP Plasmid replication protein
MDJIHKML_00498 2.8e-12
MDJIHKML_00499 1.3e-229 L Belongs to the 'phage' integrase family
MDJIHKML_00500 1.3e-69 S Iron-sulphur cluster biosynthesis
MDJIHKML_00501 5.1e-33
MDJIHKML_00502 5.9e-67
MDJIHKML_00503 3.1e-172 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
MDJIHKML_00504 5.6e-13
MDJIHKML_00505 2.1e-252 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDJIHKML_00506 2.5e-161 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MDJIHKML_00507 7.8e-70 M LysM domain protein
MDJIHKML_00508 4.1e-195 D nuclear chromosome segregation
MDJIHKML_00509 4.9e-110 5.4.2.11 G Phosphoglycerate mutase family
MDJIHKML_00510 6.6e-107 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
MDJIHKML_00511 1e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
MDJIHKML_00512 5.4e-52 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MDJIHKML_00513 3.9e-184 msmR K helix_turn _helix lactose operon repressor
MDJIHKML_00514 2.7e-249 G Bacterial extracellular solute-binding protein
MDJIHKML_00515 4.5e-163 msmF P ABC-type sugar transport systems, permease components
MDJIHKML_00516 3.3e-155 msmG G Binding-protein-dependent transport system inner membrane component
MDJIHKML_00517 5.8e-260 sacA 3.2.1.26 GH32 G Glycosyl hydrolases family 32
MDJIHKML_00518 6.5e-212 msmX P Belongs to the ABC transporter superfamily
MDJIHKML_00519 2.6e-285 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
MDJIHKML_00520 6.1e-70 EGP Major facilitator Superfamily
MDJIHKML_00522 1.3e-177 pfoS S Phosphotransferase system, EIIC
MDJIHKML_00523 3.9e-276 slpX S SLAP domain
MDJIHKML_00526 4e-209
MDJIHKML_00527 7.3e-124 gntR1 K UTRA
MDJIHKML_00528 1.5e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MDJIHKML_00529 8e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDJIHKML_00530 1.1e-206 csaB M Glycosyl transferases group 1
MDJIHKML_00531 1.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDJIHKML_00532 6.1e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDJIHKML_00533 0.0 pacL 3.6.3.8 P P-type ATPase
MDJIHKML_00534 2.9e-226 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDJIHKML_00535 1.1e-256 epsU S Polysaccharide biosynthesis protein
MDJIHKML_00536 9.7e-137 M Glycosyltransferase sugar-binding region containing DXD motif
MDJIHKML_00537 4.3e-64 ydcK S Belongs to the SprT family
MDJIHKML_00539 2.8e-114 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
MDJIHKML_00540 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MDJIHKML_00541 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDJIHKML_00542 1.1e-201 camS S sex pheromone
MDJIHKML_00543 2.6e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDJIHKML_00544 1.5e-261 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDJIHKML_00545 1.9e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDJIHKML_00546 4.2e-172 yegS 2.7.1.107 G Lipid kinase
MDJIHKML_00547 2.2e-112 ybhL S Belongs to the BI1 family
MDJIHKML_00548 4.1e-56
MDJIHKML_00549 1.5e-245 nhaC C Na H antiporter NhaC
MDJIHKML_00550 9.6e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDJIHKML_00551 1.6e-22
MDJIHKML_00552 1.1e-62
MDJIHKML_00553 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MDJIHKML_00554 3.9e-34 copZ C Heavy-metal-associated domain
MDJIHKML_00555 5e-96 dps P Belongs to the Dps family
MDJIHKML_00556 8.1e-114 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MDJIHKML_00557 2.8e-113 ung2 3.2.2.27 L Uracil-DNA glycosylase
MDJIHKML_00558 1.2e-48 5.1.1.13 M Asp/Glu/Hydantoin racemase
MDJIHKML_00559 6.5e-57 5.1.1.13 M Asp/Glu/Hydantoin racemase
MDJIHKML_00560 9e-192 L Recombinase
MDJIHKML_00561 7.8e-94 L Resolvase, N terminal domain
MDJIHKML_00562 1.4e-178 L Recombinase zinc beta ribbon domain
MDJIHKML_00563 6.6e-95 MA20_25245 K Acetyltransferase (GNAT) domain
MDJIHKML_00568 3.9e-244 emrY EGP Major facilitator Superfamily
MDJIHKML_00569 6.8e-136 S CAAX protease self-immunity
MDJIHKML_00570 5e-90 yxdD K Bacterial regulatory proteins, tetR family
MDJIHKML_00571 0.0 4.2.1.53 S Myosin-crossreactive antigen
MDJIHKML_00572 8.4e-78 2.3.1.128 K acetyltransferase
MDJIHKML_00573 8e-162 S reductase
MDJIHKML_00574 3.6e-109 V ABC-type multidrug transport system, ATPase and permease components
MDJIHKML_00575 5.1e-128 cydD V cysteine transport
MDJIHKML_00576 2.1e-241 pyrP F Permease
MDJIHKML_00577 9.5e-92 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDJIHKML_00578 1.5e-86 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MDJIHKML_00579 2.4e-50 3.1.3.102, 3.1.3.104 Q phosphatase activity
MDJIHKML_00580 1.6e-253 emrY EGP Major facilitator Superfamily
MDJIHKML_00581 4e-215 mdtG EGP Major facilitator Superfamily
MDJIHKML_00582 1.8e-165 mleP3 S Membrane transport protein
MDJIHKML_00583 2.1e-210 pepA E M42 glutamyl aminopeptidase
MDJIHKML_00584 0.0 ybiT S ABC transporter, ATP-binding protein
MDJIHKML_00585 9.8e-146
MDJIHKML_00586 9e-150 glnH ET ABC transporter
MDJIHKML_00587 2.3e-78 K Transcriptional regulator, MarR family
MDJIHKML_00588 1.1e-306 XK27_09600 V ABC transporter, ATP-binding protein
MDJIHKML_00589 0.0 V ABC transporter transmembrane region
MDJIHKML_00590 2.9e-102 S ABC-type cobalt transport system, permease component
MDJIHKML_00591 7.2e-115 udk 2.7.1.48 F Zeta toxin
MDJIHKML_00592 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDJIHKML_00593 1.3e-148 glnH ET ABC transporter substrate-binding protein
MDJIHKML_00594 6.1e-93 gluC P ABC transporter permease
MDJIHKML_00595 1.9e-110 glnP P ABC transporter permease
MDJIHKML_00596 1.5e-174 S Protein of unknown function (DUF2974)
MDJIHKML_00597 1.2e-63
MDJIHKML_00598 4.8e-238 G Bacterial extracellular solute-binding protein
MDJIHKML_00599 4.1e-163 2.7.7.12 C Domain of unknown function (DUF4931)
MDJIHKML_00600 5.9e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDJIHKML_00601 2e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDJIHKML_00602 0.0 kup P Transport of potassium into the cell
MDJIHKML_00603 6.3e-176 rihB 3.2.2.1 F Nucleoside
MDJIHKML_00604 3.3e-135 gntR K UbiC transcription regulator-associated domain protein
MDJIHKML_00605 2.6e-22
MDJIHKML_00606 1.2e-112
MDJIHKML_00607 2.9e-285 V ABC transporter transmembrane region
MDJIHKML_00608 1.8e-153 S hydrolase
MDJIHKML_00609 5.3e-72 K helix_turn_helix multiple antibiotic resistance protein
MDJIHKML_00610 0.0 lmrA 3.6.3.44 V ABC transporter
MDJIHKML_00611 1.9e-59 S Enterocin A Immunity
MDJIHKML_00612 1.3e-137 glcR K DeoR C terminal sensor domain
MDJIHKML_00613 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MDJIHKML_00614 5.3e-161 rssA S Phospholipase, patatin family
MDJIHKML_00615 3.8e-224 2.7.13.3 T GHKL domain
MDJIHKML_00616 5e-145 K LytTr DNA-binding domain
MDJIHKML_00617 3.4e-222 S CAAX protease self-immunity
MDJIHKML_00618 2.3e-153 S hydrolase
MDJIHKML_00619 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
MDJIHKML_00620 7.6e-149 glvR K Helix-turn-helix domain, rpiR family
MDJIHKML_00621 2.9e-82
MDJIHKML_00622 1.1e-86 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MDJIHKML_00623 1.9e-40
MDJIHKML_00624 1.6e-120 C nitroreductase
MDJIHKML_00625 1.1e-248 yhdP S Transporter associated domain
MDJIHKML_00626 2.2e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDJIHKML_00627 1.2e-263 L COG2963 Transposase and inactivated derivatives
MDJIHKML_00628 1.5e-228 potE E amino acid
MDJIHKML_00629 1.1e-130 M Glycosyl hydrolases family 25
MDJIHKML_00630 2.6e-209 yfmL 3.6.4.13 L DEAD DEAH box helicase
MDJIHKML_00631 1.2e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDJIHKML_00633 4.1e-217 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDJIHKML_00634 4.3e-89 gtcA S Teichoic acid glycosylation protein
MDJIHKML_00635 1.2e-79 fld C Flavodoxin
MDJIHKML_00636 1.1e-163 map 3.4.11.18 E Methionine Aminopeptidase
MDJIHKML_00637 4.1e-151 yihY S Belongs to the UPF0761 family
MDJIHKML_00638 3.3e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MDJIHKML_00639 5.1e-215 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
MDJIHKML_00640 4.6e-219 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MDJIHKML_00641 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MDJIHKML_00642 1.9e-46
MDJIHKML_00643 1.5e-177 D Alpha beta
MDJIHKML_00644 6e-263 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDJIHKML_00645 1.7e-145 recX 2.4.1.337 GT4 S Regulatory protein RecX
MDJIHKML_00646 9.1e-86
MDJIHKML_00647 1.2e-71
MDJIHKML_00648 9.5e-158 hlyX S Transporter associated domain
MDJIHKML_00649 1e-303 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDJIHKML_00650 6.7e-44 XK27_09445 S Domain of unknown function (DUF1827)
MDJIHKML_00651 0.0 clpE O Belongs to the ClpA ClpB family
MDJIHKML_00652 8.5e-41 ptsH G phosphocarrier protein HPR
MDJIHKML_00653 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDJIHKML_00654 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDJIHKML_00655 8.8e-128 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MDJIHKML_00656 1.4e-161 coiA 3.6.4.12 S Competence protein
MDJIHKML_00657 1.2e-114 yjbH Q Thioredoxin
MDJIHKML_00658 9.5e-112 yjbK S CYTH
MDJIHKML_00659 2.3e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
MDJIHKML_00660 1.6e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDJIHKML_00661 8.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDJIHKML_00662 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MDJIHKML_00663 2e-118 S SNARE associated Golgi protein
MDJIHKML_00664 1.7e-201 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MDJIHKML_00665 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
MDJIHKML_00666 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MDJIHKML_00667 3.2e-212 yubA S AI-2E family transporter
MDJIHKML_00668 1.3e-104 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDJIHKML_00669 1.8e-68 WQ51_03320 S Protein of unknown function (DUF1149)
MDJIHKML_00670 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MDJIHKML_00671 3.5e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
MDJIHKML_00672 4.5e-241 S Peptidase M16
MDJIHKML_00673 2e-132 IQ Enoyl-(Acyl carrier protein) reductase
MDJIHKML_00674 6.6e-119 ymfM S Helix-turn-helix domain
MDJIHKML_00675 9.3e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDJIHKML_00676 7.9e-194 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDJIHKML_00677 1e-221 rny S Endoribonuclease that initiates mRNA decay
MDJIHKML_00678 1.8e-212 tagO 2.7.8.33, 2.7.8.35 M transferase
MDJIHKML_00679 9.6e-118 yvyE 3.4.13.9 S YigZ family
MDJIHKML_00680 3.3e-247 comFA L Helicase C-terminal domain protein
MDJIHKML_00681 3.1e-135 comFC S Competence protein
MDJIHKML_00682 5.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDJIHKML_00683 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDJIHKML_00684 3.5e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDJIHKML_00686 5.4e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDJIHKML_00687 1.4e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDJIHKML_00688 6.1e-188 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MDJIHKML_00689 1.2e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDJIHKML_00690 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MDJIHKML_00691 2.9e-223 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MDJIHKML_00692 7.2e-214 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
MDJIHKML_00693 2.8e-287 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
MDJIHKML_00694 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MDJIHKML_00695 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
MDJIHKML_00696 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MDJIHKML_00697 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDJIHKML_00698 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDJIHKML_00699 1.1e-90 S Short repeat of unknown function (DUF308)
MDJIHKML_00700 4.8e-165 rapZ S Displays ATPase and GTPase activities
MDJIHKML_00701 8.1e-196 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MDJIHKML_00702 6.8e-170 whiA K May be required for sporulation
MDJIHKML_00703 4.7e-100 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDJIHKML_00704 0.0 S SH3-like domain
MDJIHKML_00705 1.3e-276 ycaM E amino acid
MDJIHKML_00707 8.6e-190 cggR K Putative sugar-binding domain
MDJIHKML_00708 3.8e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDJIHKML_00709 3.5e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MDJIHKML_00710 9.9e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDJIHKML_00711 1.3e-96
MDJIHKML_00712 3.1e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
MDJIHKML_00713 2.6e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDJIHKML_00714 1.8e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MDJIHKML_00715 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MDJIHKML_00716 1e-98 dnaQ 2.7.7.7 L DNA polymerase III
MDJIHKML_00717 2.4e-164 murB 1.3.1.98 M Cell wall formation
MDJIHKML_00718 9.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDJIHKML_00719 1.1e-136 potB P ABC transporter permease
MDJIHKML_00720 2.9e-132 potC P ABC transporter permease
MDJIHKML_00721 1e-206 potD P ABC transporter
MDJIHKML_00722 1.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDJIHKML_00723 1.2e-172 ybbR S YbbR-like protein
MDJIHKML_00724 3.9e-259 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDJIHKML_00725 1.3e-148 S hydrolase
MDJIHKML_00726 1.3e-145 S Sucrose-6F-phosphate phosphohydrolase
MDJIHKML_00727 1e-120
MDJIHKML_00728 1.7e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDJIHKML_00729 6.7e-212 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MDJIHKML_00730 3.4e-152 licT K CAT RNA binding domain
MDJIHKML_00731 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDJIHKML_00732 3.1e-286 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDJIHKML_00733 4.2e-175 D Alpha beta
MDJIHKML_00734 0.0 E Amino acid permease
MDJIHKML_00736 2.2e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDJIHKML_00737 1.9e-92 S VanZ like family
MDJIHKML_00738 2e-132 yebC K Transcriptional regulatory protein
MDJIHKML_00739 5.4e-178 comGA NU Type II IV secretion system protein
MDJIHKML_00740 9.9e-175 comGB NU type II secretion system
MDJIHKML_00741 2.4e-46 comGC U competence protein ComGC
MDJIHKML_00742 2e-71
MDJIHKML_00743 1e-19
MDJIHKML_00744 1.3e-86 comGF U Putative Competence protein ComGF
MDJIHKML_00745 3e-187 ytxK 2.1.1.72 L N-6 DNA Methylase
MDJIHKML_00746 2.7e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDJIHKML_00748 4.3e-121 M Protein of unknown function (DUF3737)
MDJIHKML_00749 8.1e-176 patB 4.4.1.8 E Aminotransferase, class I
MDJIHKML_00750 5.7e-29 4.4.1.8 E Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MDJIHKML_00751 2.3e-192 manA 5.3.1.8 G mannose-6-phosphate isomerase
MDJIHKML_00752 4.9e-61 S SdpI/YhfL protein family
MDJIHKML_00753 2.2e-131 K Transcriptional regulatory protein, C terminal
MDJIHKML_00754 6.2e-271 T PhoQ Sensor
MDJIHKML_00755 1.6e-61 limB 1.14.13.107, 1.14.13.162 C Luciferase-like monooxygenase
MDJIHKML_00756 2.2e-123 XK27_00915 C Luciferase-like monooxygenase
MDJIHKML_00757 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDJIHKML_00758 4.1e-107 vanZ V VanZ like family
MDJIHKML_00759 1.6e-260 pgi 5.3.1.9 G Belongs to the GPI family
MDJIHKML_00760 9.9e-250 EGP Major facilitator Superfamily
MDJIHKML_00761 1.6e-196 ampC V Beta-lactamase
MDJIHKML_00764 2e-64
MDJIHKML_00765 2.9e-287 S DNA primase
MDJIHKML_00766 1.6e-35
MDJIHKML_00767 1.9e-33
MDJIHKML_00768 8.1e-69
MDJIHKML_00769 1.4e-36
MDJIHKML_00770 2.9e-12 S Helix-turn-helix domain
MDJIHKML_00771 3.2e-58 K Transcriptional
MDJIHKML_00772 9.5e-208 sip L Belongs to the 'phage' integrase family
MDJIHKML_00773 2e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MDJIHKML_00774 4.5e-114 tdk 2.7.1.21 F thymidine kinase
MDJIHKML_00775 3.4e-181 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDJIHKML_00776 7.8e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDJIHKML_00777 3.7e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDJIHKML_00778 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDJIHKML_00779 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
MDJIHKML_00780 6.6e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDJIHKML_00781 1.7e-50 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDJIHKML_00782 1.5e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDJIHKML_00783 4.3e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDJIHKML_00784 9.8e-172 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDJIHKML_00785 2.1e-255 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDJIHKML_00786 6.9e-64 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MDJIHKML_00787 2.6e-30 ywzB S Protein of unknown function (DUF1146)
MDJIHKML_00788 1.9e-178 mbl D Cell shape determining protein MreB Mrl
MDJIHKML_00789 2.5e-49 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MDJIHKML_00790 1.5e-33 S Protein of unknown function (DUF2969)
MDJIHKML_00791 9.5e-217 rodA D Belongs to the SEDS family
MDJIHKML_00792 5.8e-77 uspA T universal stress protein
MDJIHKML_00793 4e-33
MDJIHKML_00794 4.2e-242 rarA L recombination factor protein RarA
MDJIHKML_00795 1.9e-83 yueI S Protein of unknown function (DUF1694)
MDJIHKML_00796 1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDJIHKML_00797 1.5e-292 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDJIHKML_00798 1.1e-217 iscS2 2.8.1.7 E Aminotransferase class V
MDJIHKML_00799 5.9e-230 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDJIHKML_00800 2.2e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDJIHKML_00801 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDJIHKML_00802 8.5e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MDJIHKML_00803 8.9e-127 S Haloacid dehalogenase-like hydrolase
MDJIHKML_00804 1.2e-114 radC L DNA repair protein
MDJIHKML_00805 1.1e-176 mreB D cell shape determining protein MreB
MDJIHKML_00806 7.2e-150 mreC M Involved in formation and maintenance of cell shape
MDJIHKML_00807 7.1e-95 mreD
MDJIHKML_00808 8.8e-10 S Protein of unknown function (DUF4044)
MDJIHKML_00809 3.2e-53 S Protein of unknown function (DUF3397)
MDJIHKML_00810 4e-72 mraZ K Belongs to the MraZ family
MDJIHKML_00811 2.2e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDJIHKML_00812 2.4e-54 ftsL D Cell division protein FtsL
MDJIHKML_00813 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MDJIHKML_00814 2.1e-177 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDJIHKML_00815 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDJIHKML_00816 4e-209 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDJIHKML_00817 1.2e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDJIHKML_00818 2.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDJIHKML_00819 4.2e-245 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDJIHKML_00820 2.1e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDJIHKML_00821 7.8e-29 yggT S YGGT family
MDJIHKML_00822 6.7e-150 ylmH S S4 domain protein
MDJIHKML_00823 1.9e-75 gpsB D DivIVA domain protein
MDJIHKML_00824 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDJIHKML_00825 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
MDJIHKML_00826 8.9e-104 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MDJIHKML_00827 3.4e-28
MDJIHKML_00828 5.9e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDJIHKML_00829 9.8e-58 XK27_04120 S Putative amino acid metabolism
MDJIHKML_00830 9.3e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDJIHKML_00831 4.3e-126 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MDJIHKML_00832 5.7e-115 S Repeat protein
MDJIHKML_00833 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDJIHKML_00834 3.7e-304 L Nuclease-related domain
MDJIHKML_00835 9.3e-183 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MDJIHKML_00836 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDJIHKML_00837 3.2e-33 ykzG S Belongs to the UPF0356 family
MDJIHKML_00838 1.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDJIHKML_00839 0.0 typA T GTP-binding protein TypA
MDJIHKML_00840 7.7e-211 ftsW D Belongs to the SEDS family
MDJIHKML_00841 4.3e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MDJIHKML_00842 4.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MDJIHKML_00843 6.2e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDJIHKML_00844 7.6e-194 ylbL T Belongs to the peptidase S16 family
MDJIHKML_00845 1.7e-72 comEA L Competence protein ComEA
MDJIHKML_00846 0.0 comEC S Competence protein ComEC
MDJIHKML_00847 8.8e-176 holA 2.7.7.7 L DNA polymerase III delta subunit
MDJIHKML_00848 3e-35 rpsT J Binds directly to 16S ribosomal RNA
MDJIHKML_00849 1.1e-40 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDJIHKML_00850 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDJIHKML_00851 2.2e-151
MDJIHKML_00852 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDJIHKML_00853 3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDJIHKML_00854 1.2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDJIHKML_00855 2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MDJIHKML_00856 8.9e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDJIHKML_00857 2.5e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
MDJIHKML_00858 2.9e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDJIHKML_00859 5.7e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDJIHKML_00860 2.8e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDJIHKML_00861 3.7e-176 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDJIHKML_00862 3.9e-142 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDJIHKML_00863 5.3e-220 aspC 2.6.1.1 E Aminotransferase
MDJIHKML_00864 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDJIHKML_00865 9.2e-206 pbpX1 V Beta-lactamase
MDJIHKML_00866 1.3e-298 I Protein of unknown function (DUF2974)
MDJIHKML_00867 8.6e-41 C FMN_bind
MDJIHKML_00868 1.6e-80
MDJIHKML_00869 1.9e-286
MDJIHKML_00870 5.2e-178 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
MDJIHKML_00871 8.5e-145
MDJIHKML_00872 2.7e-10
MDJIHKML_00875 6.1e-19 alkD L DNA alkylation repair enzyme
MDJIHKML_00876 1.5e-67 alkD L DNA alkylation repair enzyme
MDJIHKML_00877 6e-39 S Transglycosylase associated protein
MDJIHKML_00879 2.4e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDJIHKML_00880 2.2e-128 K UTRA domain
MDJIHKML_00881 4.5e-55 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MDJIHKML_00882 6.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MDJIHKML_00883 1.2e-80
MDJIHKML_00884 4.4e-138 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDJIHKML_00885 1.2e-70 S Domain of unknown function (DUF3284)
MDJIHKML_00886 6.3e-303 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDJIHKML_00887 4.7e-134 gmuR K UTRA
MDJIHKML_00888 3.5e-41
MDJIHKML_00889 2.4e-267 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDJIHKML_00890 9.5e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDJIHKML_00891 6.8e-156 ypbG 2.7.1.2 GK ROK family
MDJIHKML_00892 1.6e-85 C Nitroreductase family
MDJIHKML_00893 1.3e-108 S Domain of unknown function (DUF4767)
MDJIHKML_00894 8.1e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDJIHKML_00895 6.8e-153 yitS S Uncharacterised protein, DegV family COG1307
MDJIHKML_00896 1.7e-99 3.6.1.27 I Acid phosphatase homologues
MDJIHKML_00897 8.7e-192 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDJIHKML_00899 4.3e-180 L Belongs to the 'phage' integrase family
MDJIHKML_00900 2.4e-11
MDJIHKML_00901 5.8e-83
MDJIHKML_00903 1.2e-55 ansR 3.4.21.88 K Cro/C1-type HTH DNA-binding domain
MDJIHKML_00904 4.4e-29 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MDJIHKML_00905 8.1e-252 yifK E Amino acid permease
MDJIHKML_00906 6.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDJIHKML_00907 5.6e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDJIHKML_00908 0.0 aha1 P E1-E2 ATPase
MDJIHKML_00909 5e-159 metQ1 P Belongs to the nlpA lipoprotein family
MDJIHKML_00910 2.2e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDJIHKML_00911 7.6e-81 metI P ABC transporter permease
MDJIHKML_00912 1e-265 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDJIHKML_00913 2e-266 frdC 1.3.5.4 C FAD binding domain
MDJIHKML_00914 8e-293 M domain protein
MDJIHKML_00915 2.6e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDJIHKML_00916 1.2e-257 pepC 3.4.22.40 E Peptidase C1-like family
MDJIHKML_00917 1.2e-274 P Sodium:sulfate symporter transmembrane region
MDJIHKML_00918 1.1e-155 ydjP I Alpha/beta hydrolase family
MDJIHKML_00919 8.2e-196 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MDJIHKML_00920 4.1e-44 citD C Covalent carrier of the coenzyme of citrate lyase
MDJIHKML_00921 1.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
MDJIHKML_00922 9.2e-289 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
MDJIHKML_00924 9.3e-72 yeaL S Protein of unknown function (DUF441)
MDJIHKML_00925 3.3e-13
MDJIHKML_00926 3.8e-148 cbiQ P cobalt transport
MDJIHKML_00927 0.0 ykoD P ABC transporter, ATP-binding protein
MDJIHKML_00928 7.4e-95 S UPF0397 protein
MDJIHKML_00929 1.3e-63 S Domain of unknown function DUF1828
MDJIHKML_00930 2.2e-54
MDJIHKML_00931 1.2e-177 citR K Putative sugar-binding domain
MDJIHKML_00932 5.5e-245 yjjP S Putative threonine/serine exporter
MDJIHKML_00933 1.5e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDJIHKML_00934 2.1e-174 prmA J Ribosomal protein L11 methyltransferase
MDJIHKML_00935 4e-49
MDJIHKML_00936 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDJIHKML_00937 1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDJIHKML_00938 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MDJIHKML_00939 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MDJIHKML_00940 2.5e-225 patA 2.6.1.1 E Aminotransferase
MDJIHKML_00941 2.8e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDJIHKML_00942 3.5e-154 S reductase
MDJIHKML_00943 1.6e-151 yxeH S hydrolase
MDJIHKML_00944 3.1e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDJIHKML_00945 3.9e-230 yfnA E Amino Acid
MDJIHKML_00946 2.2e-108 dedA 3.1.3.1 S SNARE associated Golgi protein
MDJIHKML_00947 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDJIHKML_00948 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDJIHKML_00949 0.0 I Acyltransferase
MDJIHKML_00950 2.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDJIHKML_00951 7.2e-144 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MDJIHKML_00952 5.1e-32 yrvD S Lipopolysaccharide assembly protein A domain
MDJIHKML_00953 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MDJIHKML_00954 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MDJIHKML_00956 0.0 dnaE 2.7.7.7 L DNA polymerase
MDJIHKML_00957 7.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDJIHKML_00958 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MDJIHKML_00959 5e-170 cvfB S S1 domain
MDJIHKML_00960 1.6e-168 xerD D recombinase XerD
MDJIHKML_00961 1.7e-60 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDJIHKML_00962 1.3e-131 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDJIHKML_00963 3.2e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDJIHKML_00964 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDJIHKML_00965 2.2e-117 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDJIHKML_00966 1.1e-46 M Lysin motif
MDJIHKML_00967 8.4e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MDJIHKML_00968 2.3e-202 rpsA 1.17.7.4 J Ribosomal protein S1
MDJIHKML_00969 1.3e-246 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MDJIHKML_00970 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDJIHKML_00971 2.1e-230 S Tetratricopeptide repeat protein
MDJIHKML_00972 1.3e-162 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDJIHKML_00973 1.1e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDJIHKML_00974 1.2e-107 hlyIII S protein, hemolysin III
MDJIHKML_00975 2.1e-149 DegV S Uncharacterised protein, DegV family COG1307
MDJIHKML_00976 2.7e-35 yozE S Belongs to the UPF0346 family
MDJIHKML_00977 3.5e-283 yjcE P Sodium proton antiporter
MDJIHKML_00978 1e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDJIHKML_00979 1.1e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDJIHKML_00980 3.6e-157 dprA LU DNA protecting protein DprA
MDJIHKML_00981 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDJIHKML_00982 6.1e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDJIHKML_00983 7.3e-169 xerC D Phage integrase, N-terminal SAM-like domain
MDJIHKML_00984 1.1e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDJIHKML_00985 1.7e-233 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDJIHKML_00986 1.8e-180 lacX 5.1.3.3 G Aldose 1-epimerase
MDJIHKML_00987 1.5e-65
MDJIHKML_00988 3.8e-232 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDJIHKML_00989 3.2e-158 S Alpha/beta hydrolase of unknown function (DUF915)
MDJIHKML_00990 1.4e-150 xerD L Phage integrase, N-terminal SAM-like domain
MDJIHKML_00991 3.5e-67 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDJIHKML_00992 1.1e-62 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDJIHKML_00993 6.9e-275 pepV 3.5.1.18 E dipeptidase PepV
MDJIHKML_00994 5.3e-286 E Amino acid permease
MDJIHKML_00995 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MDJIHKML_00996 3.2e-247 ynbB 4.4.1.1 P aluminum resistance
MDJIHKML_00997 3.9e-119 ktrA P domain protein
MDJIHKML_00998 4e-240 ktrB P Potassium uptake protein
MDJIHKML_00999 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MDJIHKML_01000 1.7e-81 C Flavodoxin
MDJIHKML_01001 0.0 uvrA3 L excinuclease ABC, A subunit
MDJIHKML_01002 5.9e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MDJIHKML_01003 1.8e-113 3.6.1.27 I Acid phosphatase homologues
MDJIHKML_01004 4.5e-67 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDJIHKML_01005 1.9e-208 pbpX1 V Beta-lactamase
MDJIHKML_01006 1.5e-155 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MDJIHKML_01007 3.1e-93 S ECF-type riboflavin transporter, S component
MDJIHKML_01008 2.1e-216 S Putative peptidoglycan binding domain
MDJIHKML_01009 6.5e-241
MDJIHKML_01010 0.0 treB 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDJIHKML_01011 2.9e-128 treR K UTRA
MDJIHKML_01012 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MDJIHKML_01013 2.8e-128 M Glycosyl transferases group 1
MDJIHKML_01014 3.8e-99 UW LPXTG-motif cell wall anchor domain protein
MDJIHKML_01015 2.4e-164 M domain protein
MDJIHKML_01016 2.6e-21 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
MDJIHKML_01017 0.0 UW LPXTG-motif cell wall anchor domain protein
MDJIHKML_01018 0.0 UW LPXTG-motif cell wall anchor domain protein
MDJIHKML_01019 1.2e-28 K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MDJIHKML_01020 8.8e-164 rocF 3.5.3.1, 3.5.3.11 E Arginase family
MDJIHKML_01021 2.1e-114 ylbE GM NAD dependent epimerase dehydratase family protein
MDJIHKML_01022 6.6e-159 K Transcriptional regulator
MDJIHKML_01023 7.7e-168 S Oxidoreductase, aldo keto reductase family protein
MDJIHKML_01024 4.3e-166 akr5f 1.1.1.346 S reductase
MDJIHKML_01025 2.7e-165 yvgN C Aldo keto reductase
MDJIHKML_01026 4.1e-217 S SLAP domain
MDJIHKML_01027 4.1e-103 yyaR K Acetyltransferase (GNAT) domain
MDJIHKML_01030 6.8e-104
MDJIHKML_01031 6.8e-78 K Transcriptional regulator
MDJIHKML_01032 1.9e-245 brnQ U Component of the transport system for branched-chain amino acids
MDJIHKML_01033 3e-164 S reductase
MDJIHKML_01034 1.3e-170
MDJIHKML_01035 4.2e-33 K Transcriptional regulator
MDJIHKML_01036 9.3e-113 papP P ABC transporter, permease protein
MDJIHKML_01037 2.2e-77 P ABC transporter permease
MDJIHKML_01038 3.5e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDJIHKML_01039 7.7e-160 cjaA ET ABC transporter substrate-binding protein
MDJIHKML_01040 8.3e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MDJIHKML_01041 8.7e-110 5.4.2.11 G Phosphoglycerate mutase family
MDJIHKML_01042 3.4e-174 4.1.1.45 S Amidohydrolase
MDJIHKML_01043 1.1e-29
MDJIHKML_01044 2.5e-109
MDJIHKML_01045 4.9e-108
MDJIHKML_01046 1.3e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
MDJIHKML_01047 2.3e-215 ynfM EGP Major facilitator Superfamily
MDJIHKML_01048 1e-153 K Bacterial regulatory helix-turn-helix protein, lysR family
MDJIHKML_01049 8.2e-119 3.6.1.55 F NUDIX domain
MDJIHKML_01050 1.3e-76
MDJIHKML_01051 3.6e-87 FG HIT domain
MDJIHKML_01052 1.1e-62
MDJIHKML_01053 3.7e-93 rimL J Acetyltransferase (GNAT) domain
MDJIHKML_01054 1.1e-101 S Alpha/beta hydrolase family
MDJIHKML_01055 9.7e-101
MDJIHKML_01056 1.3e-71
MDJIHKML_01057 1.5e-146 2.4.2.3 F Phosphorylase superfamily
MDJIHKML_01058 6.2e-108 5.4.2.11 G Phosphoglycerate mutase family
MDJIHKML_01059 5.1e-147 2.4.2.3 F Phosphorylase superfamily
MDJIHKML_01060 1.4e-144 2.4.2.3 F Phosphorylase superfamily
MDJIHKML_01061 1.4e-112 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MDJIHKML_01062 7.2e-36
MDJIHKML_01063 8.3e-53 mleP S Sodium Bile acid symporter family
MDJIHKML_01064 1.5e-91
MDJIHKML_01065 1.3e-38
MDJIHKML_01066 1.8e-167 mleR K LysR family
MDJIHKML_01067 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MDJIHKML_01068 1.9e-101 ltrA S Bacterial low temperature requirement A protein (LtrA)
MDJIHKML_01069 4.4e-244 yrvN L AAA C-terminal domain
MDJIHKML_01070 2.9e-195 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDJIHKML_01071 7.7e-114 S L,D-transpeptidase catalytic domain
MDJIHKML_01072 4.7e-218 2.1.1.14 E methionine synthase, vitamin-B12 independent
MDJIHKML_01073 2.3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDJIHKML_01074 7.9e-67 L nuclease
MDJIHKML_01075 3.3e-155 F DNA/RNA non-specific endonuclease
MDJIHKML_01076 4.3e-115 ywnB S NAD(P)H-binding
MDJIHKML_01077 1.8e-240 steT E amino acid
MDJIHKML_01078 4.4e-106 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MDJIHKML_01079 2.4e-40 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MDJIHKML_01080 2.2e-148 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MDJIHKML_01081 0.0 ppc 4.1.1.31 C phosphoenolpyruvate carboxylase activity
MDJIHKML_01082 0.0
MDJIHKML_01083 0.0
MDJIHKML_01084 3.5e-174 yobV1 K WYL domain
MDJIHKML_01085 3.1e-83 XK26_02160 S Pyridoxamine 5'-phosphate oxidase
MDJIHKML_01086 2.6e-146 IQ reductase
MDJIHKML_01087 7.1e-55 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MDJIHKML_01088 7.2e-115 tas C Aldo/keto reductase family
MDJIHKML_01089 2.9e-60 C aldo keto reductase
MDJIHKML_01090 3.6e-146 glcU U ribose uptake protein RbsU
MDJIHKML_01091 1e-20 C Flavodoxin
MDJIHKML_01093 2.7e-98 fldA C Flavodoxin
MDJIHKML_01094 7.7e-100 P esterase
MDJIHKML_01095 2.4e-261 gor 1.8.1.7 C Glutathione reductase
MDJIHKML_01096 4.1e-23
MDJIHKML_01097 4.2e-141 fldA C Flavodoxin
MDJIHKML_01098 7.8e-97 S LexA-binding, inner membrane-associated putative hydrolase
MDJIHKML_01099 2.3e-14 C Flavodoxin
MDJIHKML_01100 2.6e-149 P FAD-binding domain
MDJIHKML_01101 3.3e-77 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MDJIHKML_01103 3e-251 yagE E amino acid
MDJIHKML_01104 1.3e-12 S Alpha beta hydrolase
MDJIHKML_01105 5e-44 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDJIHKML_01106 9.2e-17 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDJIHKML_01107 2.2e-18 magIII L Base excision DNA repair protein, HhH-GPD family
MDJIHKML_01108 1.9e-168 MA20_14895 S Conserved hypothetical protein 698
MDJIHKML_01109 7e-101
MDJIHKML_01110 1.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDJIHKML_01111 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDJIHKML_01112 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDJIHKML_01113 7.8e-185 K Transcriptional regulator
MDJIHKML_01114 2.3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
MDJIHKML_01115 1.7e-113 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDJIHKML_01116 1.2e-39 K Helix-turn-helix domain
MDJIHKML_01117 1.1e-127 yoaK S Protein of unknown function (DUF1275)
MDJIHKML_01118 8.2e-66 fic D Fic/DOC family
MDJIHKML_01120 1.5e-286 V ABC-type multidrug transport system, ATPase and permease components
MDJIHKML_01121 2.3e-287 V ABC-type multidrug transport system, ATPase and permease components
MDJIHKML_01122 1e-213 EGP Transmembrane secretion effector
MDJIHKML_01123 3.9e-84 K transcriptional
MDJIHKML_01124 3.3e-58 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDJIHKML_01126 4.3e-200 M Glycosyl hydrolases family 25
MDJIHKML_01127 2.4e-107 XK27_00160 S Domain of unknown function (DUF5052)
MDJIHKML_01128 1.5e-91 adk 2.7.4.3 F topology modulation protein
MDJIHKML_01129 3.1e-59
MDJIHKML_01130 8.4e-196 xerS L Belongs to the 'phage' integrase family
MDJIHKML_01131 6.1e-160 degV S EDD domain protein, DegV family
MDJIHKML_01132 9e-66
MDJIHKML_01133 0.0 FbpA K Fibronectin-binding protein
MDJIHKML_01134 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
MDJIHKML_01135 3e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MDJIHKML_01136 3.2e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDJIHKML_01137 3.6e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDJIHKML_01138 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MDJIHKML_01139 7.2e-244 cpdA S Calcineurin-like phosphoesterase
MDJIHKML_01140 1.8e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MDJIHKML_01141 6.7e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDJIHKML_01142 9.4e-106 ypsA S Belongs to the UPF0398 family
MDJIHKML_01143 7.8e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDJIHKML_01144 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MDJIHKML_01145 1.5e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDJIHKML_01146 5.7e-115 dnaD L DnaD domain protein
MDJIHKML_01147 2.4e-253 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MDJIHKML_01148 1.4e-89 ypmB S Protein conserved in bacteria
MDJIHKML_01149 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MDJIHKML_01150 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MDJIHKML_01151 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MDJIHKML_01152 6.6e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
MDJIHKML_01153 4.1e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MDJIHKML_01154 8.4e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MDJIHKML_01155 4.2e-189 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDJIHKML_01156 5.2e-145 K SIS domain
MDJIHKML_01157 1.3e-107 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MDJIHKML_01158 4.4e-55 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MDJIHKML_01159 4.6e-216 iscS 2.8.1.7 E Aminotransferase class V
MDJIHKML_01160 1.1e-267 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
MDJIHKML_01161 3.8e-179
MDJIHKML_01162 4.1e-141
MDJIHKML_01163 8.9e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MDJIHKML_01164 2.2e-27
MDJIHKML_01165 6.8e-131
MDJIHKML_01166 4e-145
MDJIHKML_01167 3.9e-132
MDJIHKML_01168 1.1e-122 skfE V ATPases associated with a variety of cellular activities
MDJIHKML_01169 8e-61 yvoA_1 K Transcriptional regulator, GntR family
MDJIHKML_01170 1.3e-245 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MDJIHKML_01171 7.7e-154 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDJIHKML_01172 1.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
MDJIHKML_01173 5.6e-82 mutT 3.6.1.55 F NUDIX domain
MDJIHKML_01174 1.1e-126 S Peptidase family M23
MDJIHKML_01175 1.4e-198 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDJIHKML_01176 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDJIHKML_01177 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MDJIHKML_01178 2.3e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MDJIHKML_01179 1.7e-134 recO L Involved in DNA repair and RecF pathway recombination
MDJIHKML_01180 8.7e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDJIHKML_01181 7.9e-99 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDJIHKML_01182 1.3e-176 phoH T phosphate starvation-inducible protein PhoH
MDJIHKML_01183 6.5e-70 yqeY S YqeY-like protein
MDJIHKML_01184 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MDJIHKML_01185 4e-153 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDJIHKML_01186 1.3e-95 S Peptidase family M23
MDJIHKML_01187 2.8e-110 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDJIHKML_01188 2.2e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDJIHKML_01189 4.8e-122
MDJIHKML_01190 4.8e-162 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDJIHKML_01191 1.3e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MDJIHKML_01192 6.4e-287 thrC 4.2.3.1 E Threonine synthase
MDJIHKML_01193 9.4e-261 lysC 2.7.2.4 E Belongs to the aspartokinase family
MDJIHKML_01194 0.0 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
MDJIHKML_01195 1.1e-18 yjgN S Bacterial protein of unknown function (DUF898)
MDJIHKML_01196 2.8e-103 lacA 2.3.1.79 S Transferase hexapeptide repeat
MDJIHKML_01197 0.0
MDJIHKML_01198 2e-10
MDJIHKML_01199 4.5e-252 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MDJIHKML_01200 6.4e-201 brnQ U Component of the transport system for branched-chain amino acids
MDJIHKML_01201 1.3e-295
MDJIHKML_01202 1.1e-121 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
MDJIHKML_01203 1.3e-99
MDJIHKML_01204 2.2e-108 K LysR substrate binding domain
MDJIHKML_01205 3.7e-15
MDJIHKML_01206 4.8e-229 S Sterol carrier protein domain
MDJIHKML_01207 4.8e-99 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MDJIHKML_01208 1.5e-155 lysR5 K LysR substrate binding domain
MDJIHKML_01209 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
MDJIHKML_01210 1.8e-87 3.4.21.96 S SLAP domain
MDJIHKML_01211 3.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDJIHKML_01212 4.6e-151 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MDJIHKML_01213 1.6e-171 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MDJIHKML_01214 1.1e-211 S Bacterial protein of unknown function (DUF871)
MDJIHKML_01215 4.7e-151 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MDJIHKML_01217 2.9e-78 K Acetyltransferase (GNAT) domain
MDJIHKML_01218 3.7e-96 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDJIHKML_01219 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MDJIHKML_01220 4.8e-120 srtA 3.4.22.70 M sortase family
MDJIHKML_01221 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDJIHKML_01222 7.8e-200 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDJIHKML_01223 0.0 dnaK O Heat shock 70 kDa protein
MDJIHKML_01224 1.9e-77 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDJIHKML_01225 1.7e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDJIHKML_01226 2.5e-283 lsa S ABC transporter
MDJIHKML_01227 5.2e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MDJIHKML_01228 1e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDJIHKML_01229 3.3e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDJIHKML_01230 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDJIHKML_01231 8.4e-48 rplGA J ribosomal protein
MDJIHKML_01232 1.4e-47 ylxR K Protein of unknown function (DUF448)
MDJIHKML_01233 3.3e-198 nusA K Participates in both transcription termination and antitermination
MDJIHKML_01234 7.2e-83 rimP J Required for maturation of 30S ribosomal subunits
MDJIHKML_01235 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDJIHKML_01236 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDJIHKML_01237 2.6e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MDJIHKML_01238 1.7e-145 cdsA 2.7.7.41 I Belongs to the CDS family
MDJIHKML_01239 9.3e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDJIHKML_01240 8.7e-88 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDJIHKML_01241 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MDJIHKML_01242 2.4e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDJIHKML_01243 1.1e-141 rpsB J Belongs to the universal ribosomal protein uS2 family
MDJIHKML_01244 1.3e-198 yabB 2.1.1.223 L Methyltransferase small domain
MDJIHKML_01245 6.4e-116 plsC 2.3.1.51 I Acyltransferase
MDJIHKML_01246 1e-231 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MDJIHKML_01247 0.0 pepO 3.4.24.71 O Peptidase family M13
MDJIHKML_01248 3.6e-292 mdlB V ABC transporter
MDJIHKML_01249 0.0 mdlA V ABC transporter
MDJIHKML_01250 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
MDJIHKML_01251 1.1e-37 ynzC S UPF0291 protein
MDJIHKML_01252 1.5e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDJIHKML_01253 3.1e-144 E GDSL-like Lipase/Acylhydrolase family
MDJIHKML_01254 3.7e-122 ung2 3.2.2.27 L Uracil-DNA glycosylase
MDJIHKML_01255 3.4e-177 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MDJIHKML_01256 0.0 S Bacterial membrane protein, YfhO
MDJIHKML_01257 3.7e-70 2.4.1.83 GT2 S GtrA-like protein
MDJIHKML_01258 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDJIHKML_01259 5e-128 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MDJIHKML_01260 4.7e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDJIHKML_01261 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MDJIHKML_01262 2.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDJIHKML_01263 1.6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDJIHKML_01264 3.2e-259 yfnA E amino acid
MDJIHKML_01265 2.8e-67
MDJIHKML_01266 2.5e-288 pipD E Dipeptidase
MDJIHKML_01267 2.1e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDJIHKML_01268 0.0 smc D Required for chromosome condensation and partitioning
MDJIHKML_01269 3.8e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDJIHKML_01270 1.2e-263 L COG2963 Transposase and inactivated derivatives
MDJIHKML_01271 0.0 oppA E ABC transporter substrate-binding protein
MDJIHKML_01272 0.0 oppA E ABC transporter substrate-binding protein
MDJIHKML_01273 2.9e-144 oppC P Binding-protein-dependent transport system inner membrane component
MDJIHKML_01274 2.3e-176 oppB P ABC transporter permease
MDJIHKML_01275 6.1e-177 oppF P Belongs to the ABC transporter superfamily
MDJIHKML_01276 2.5e-197 oppD P Belongs to the ABC transporter superfamily
MDJIHKML_01277 5.7e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDJIHKML_01278 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDJIHKML_01279 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDJIHKML_01280 2.4e-306 yloV S DAK2 domain fusion protein YloV
MDJIHKML_01281 6.8e-57 asp S Asp23 family, cell envelope-related function
MDJIHKML_01282 3.7e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MDJIHKML_01283 4.2e-52
MDJIHKML_01284 6.9e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
MDJIHKML_01285 4.5e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MDJIHKML_01286 8e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDJIHKML_01287 0.0 KLT serine threonine protein kinase
MDJIHKML_01288 2.3e-139 stp 3.1.3.16 T phosphatase
MDJIHKML_01289 1.3e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDJIHKML_01290 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDJIHKML_01291 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDJIHKML_01292 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDJIHKML_01293 1.5e-112 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MDJIHKML_01294 1.8e-80 6.3.3.2 S ASCH
MDJIHKML_01295 4.7e-310 recN L May be involved in recombinational repair of damaged DNA
MDJIHKML_01296 3.5e-154 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MDJIHKML_01297 6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDJIHKML_01298 3.4e-36 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDJIHKML_01299 7.3e-213 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDJIHKML_01300 1.9e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDJIHKML_01301 3.6e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDJIHKML_01302 6.8e-72 yqhY S Asp23 family, cell envelope-related function
MDJIHKML_01303 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDJIHKML_01304 3.2e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MDJIHKML_01305 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MDJIHKML_01306 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MDJIHKML_01307 2e-149 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDJIHKML_01308 6.8e-259 S Uncharacterized protein conserved in bacteria (DUF2325)
MDJIHKML_01309 1.8e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MDJIHKML_01310 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MDJIHKML_01311 1.3e-105 Q Imidazolonepropionase and related amidohydrolases
MDJIHKML_01312 3.2e-109 Q Imidazolonepropionase and related amidohydrolases
MDJIHKML_01314 6.7e-60 oppA E ABC transporter
MDJIHKML_01315 9.2e-98 E ABC transporter
MDJIHKML_01316 3.7e-153 neo 2.7.1.87, 2.7.1.95 F Belongs to the aminoglycoside phosphotransferase family
MDJIHKML_01317 5e-311 S Predicted membrane protein (DUF2207)
MDJIHKML_01318 3.6e-154 cinI S Serine hydrolase (FSH1)
MDJIHKML_01319 1.7e-115 M Glycosyl hydrolases family 25
MDJIHKML_01320 1.6e-74 M Glycosyl hydrolases family 25
MDJIHKML_01322 1.7e-165 S Membrane
MDJIHKML_01323 6.5e-178 I Carboxylesterase family
MDJIHKML_01324 1e-65 arsC 1.20.4.1 P Belongs to the ArsC family
MDJIHKML_01325 5.2e-295 V ABC-type multidrug transport system, ATPase and permease components
MDJIHKML_01326 8.5e-290 V ABC-type multidrug transport system, ATPase and permease components
MDJIHKML_01327 1.5e-152 S haloacid dehalogenase-like hydrolase
MDJIHKML_01328 1.8e-206
MDJIHKML_01329 1.2e-163
MDJIHKML_01330 0.0 lacA 3.2.1.23 G -beta-galactosidase
MDJIHKML_01331 0.0 yic1 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
MDJIHKML_01332 7.7e-309 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDJIHKML_01333 1.1e-166 bglK 2.7.1.2, 2.7.1.85 GK ROK family
MDJIHKML_01334 7.3e-206 xylR GK ROK family
MDJIHKML_01335 1.8e-237 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDJIHKML_01336 6.4e-100 S Bacterial PH domain
MDJIHKML_01337 3.4e-16
MDJIHKML_01338 4.2e-65 ps301 K sequence-specific DNA binding
MDJIHKML_01339 2.3e-47 S Motility quorum-sensing regulator, toxin of MqsA
MDJIHKML_01340 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MDJIHKML_01341 8.1e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MDJIHKML_01342 4.9e-47
MDJIHKML_01343 6.6e-151 glcU U sugar transport
MDJIHKML_01344 0.0
MDJIHKML_01346 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MDJIHKML_01347 7.1e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MDJIHKML_01348 6.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDJIHKML_01349 8.5e-184 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MDJIHKML_01350 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDJIHKML_01351 9.8e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDJIHKML_01352 1.5e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDJIHKML_01353 6.4e-119 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDJIHKML_01354 1.2e-117 GM NmrA-like family
MDJIHKML_01355 0.0 3.6.3.8 P P-type ATPase
MDJIHKML_01356 1.8e-248 clcA P chloride
MDJIHKML_01357 5.2e-103 O Matrixin
MDJIHKML_01358 0.0 UW LPXTG-motif cell wall anchor domain protein
MDJIHKML_01359 8.8e-95 wecD K acetyltransferase
MDJIHKML_01360 1e-50
MDJIHKML_01361 1.5e-147 metQ2 P Belongs to the nlpA lipoprotein family
MDJIHKML_01362 8.8e-47
MDJIHKML_01363 8.1e-125 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MDJIHKML_01364 9e-156 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MDJIHKML_01365 5.7e-52 S Iron-sulfur cluster assembly protein
MDJIHKML_01366 0.0 oppA E ABC transporter substrate-binding protein
MDJIHKML_01368 9.1e-264 npr 1.11.1.1 C NADH oxidase
MDJIHKML_01369 3.9e-62 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
MDJIHKML_01370 4.6e-45 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MDJIHKML_01371 1.5e-115 ylbE GM NAD(P)H-binding
MDJIHKML_01372 1.7e-57 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDJIHKML_01373 2.4e-65 S ASCH domain
MDJIHKML_01374 1.1e-118 S GyrI-like small molecule binding domain
MDJIHKML_01376 3.4e-160 K Bacterial regulatory helix-turn-helix protein, lysR family
MDJIHKML_01377 0.0 1.3.5.4 C FMN_bind
MDJIHKML_01380 2e-208 2.7.7.65 T GGDEF domain
MDJIHKML_01381 1e-130 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MDJIHKML_01382 3.6e-143 T EAL domain
MDJIHKML_01383 1.5e-244 pgaC GT2 M Glycosyl transferase
MDJIHKML_01384 1e-90
MDJIHKML_01385 5.7e-177 C Oxidoreductase
MDJIHKML_01386 8.1e-09 L Probable transposase
MDJIHKML_01387 9.3e-214 L TIGRFAM transposase, IS605 OrfB family
MDJIHKML_01388 6e-27 C pentaerythritol trinitrate reductase activity
MDJIHKML_01389 4e-109 pncA Q Isochorismatase family
MDJIHKML_01390 2.9e-13
MDJIHKML_01391 1.1e-278 yjeM E Amino Acid
MDJIHKML_01392 2.4e-127 S Alpha beta hydrolase
MDJIHKML_01394 2.4e-128
MDJIHKML_01395 9e-127 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
MDJIHKML_01396 9.2e-71 O OsmC-like protein
MDJIHKML_01397 1.8e-212 EGP Major facilitator Superfamily
MDJIHKML_01398 1.2e-233 sptS 2.7.13.3 T Histidine kinase
MDJIHKML_01399 1.5e-118 K response regulator
MDJIHKML_01400 1.7e-113 2.7.6.5 T Region found in RelA / SpoT proteins
MDJIHKML_01401 2.3e-187 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MDJIHKML_01402 1.2e-103 dhaL 2.7.1.121 S Dak2
MDJIHKML_01403 2.1e-61 dhaM 2.7.1.121 S PTS system fructose IIA component
MDJIHKML_01404 5.6e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MDJIHKML_01405 1.6e-282 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
MDJIHKML_01406 0.0 rafA 3.2.1.22 G alpha-galactosidase
MDJIHKML_01407 2.3e-209 msmX P Belongs to the ABC transporter superfamily
MDJIHKML_01408 1.5e-152 msmG P Binding-protein-dependent transport system inner membrane component
MDJIHKML_01409 1.8e-156 msmF P Binding-protein-dependent transport system inner membrane component
MDJIHKML_01410 4e-242 msmE G Bacterial extracellular solute-binding protein
MDJIHKML_01411 3.7e-159 msmR K helix_turn_helix, arabinose operon control protein
MDJIHKML_01412 5e-75 merR K MerR HTH family regulatory protein
MDJIHKML_01413 1.6e-266 lmrB EGP Major facilitator Superfamily
MDJIHKML_01414 1.1e-96 S Domain of unknown function (DUF4811)
MDJIHKML_01415 5.3e-52 S Domain of unknown function (DUF4160)
MDJIHKML_01416 1.2e-45
MDJIHKML_01418 1.1e-39 C FMN binding
MDJIHKML_01419 1.8e-167 S SLAP domain
MDJIHKML_01420 3.2e-194 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MDJIHKML_01421 4.3e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MDJIHKML_01422 2.3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDJIHKML_01423 2.3e-187 M domain protein
MDJIHKML_01424 8.8e-113
MDJIHKML_01425 0.0 lacZ 3.2.1.23 G -beta-galactosidase
MDJIHKML_01426 0.0 lacS G Transporter
MDJIHKML_01427 4.6e-224 L Putative transposase DNA-binding domain
MDJIHKML_01428 1.2e-188 lacR K Transcriptional regulator
MDJIHKML_01429 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MDJIHKML_01430 4.3e-188 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MDJIHKML_01431 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MDJIHKML_01432 4.7e-309 2.7.7.7 S Domain of unknown function (DUF5060)
MDJIHKML_01433 1.3e-216 uhpT EGP Major facilitator Superfamily
MDJIHKML_01434 2.1e-174 rbsR K helix_turn _helix lactose operon repressor
MDJIHKML_01435 0.0 3.2.1.40 G Alpha-L-rhamnosidase N-terminal domain
MDJIHKML_01436 8.1e-60 G polysaccharide catabolic process
MDJIHKML_01437 2.1e-263 L COG2963 Transposase and inactivated derivatives
MDJIHKML_01438 1e-78 G YdjC-like protein
MDJIHKML_01439 7.3e-177 I alpha/beta hydrolase fold
MDJIHKML_01440 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDJIHKML_01441 5.7e-155 licT K CAT RNA binding domain
MDJIHKML_01442 2.4e-258 G Protein of unknown function (DUF4038)
MDJIHKML_01443 5.7e-175 rbsB G Periplasmic binding protein domain
MDJIHKML_01444 2e-147 rbsC U Belongs to the binding-protein-dependent transport system permease family
MDJIHKML_01446 2.7e-277 rbsA 3.6.3.17 G ABC transporter
MDJIHKML_01447 3.9e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDJIHKML_01448 8e-163 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDJIHKML_01449 1.7e-289 G isomerase
MDJIHKML_01450 4.6e-224 L Putative transposase DNA-binding domain
MDJIHKML_01451 6e-188 purR13 K Bacterial regulatory proteins, lacI family
MDJIHKML_01452 1.2e-154 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
MDJIHKML_01453 1.3e-176 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
MDJIHKML_01454 1.6e-258 glpK_1 2.7.1.30 G FGGY family of carbohydrate kinases, C-terminal domain
MDJIHKML_01455 7.4e-225 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDJIHKML_01456 1.9e-248 lmrB EGP Major facilitator Superfamily
MDJIHKML_01459 4.1e-152
MDJIHKML_01460 4e-167
MDJIHKML_01461 1.8e-116 ybbL S ABC transporter, ATP-binding protein
MDJIHKML_01462 5.5e-133 ybbM S Uncharacterised protein family (UPF0014)
MDJIHKML_01463 8.9e-264 glnA 6.3.1.2 E glutamine synthetase
MDJIHKML_01464 1.9e-239 ynbB 4.4.1.1 P aluminum resistance
MDJIHKML_01465 2.1e-171 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDJIHKML_01466 3.3e-65 yqhL P Rhodanese-like protein
MDJIHKML_01467 1.6e-32 yqgQ S Bacterial protein of unknown function (DUF910)
MDJIHKML_01468 1.2e-118 gluP 3.4.21.105 S Rhomboid family
MDJIHKML_01469 1.1e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDJIHKML_01470 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDJIHKML_01471 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MDJIHKML_01472 0.0 S membrane
MDJIHKML_01473 2.3e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
MDJIHKML_01474 0.0 O Belongs to the peptidase S8 family
MDJIHKML_01475 1.7e-35 ltrA S Bacterial low temperature requirement A protein (LtrA)
MDJIHKML_01476 1.1e-12 ltrA S Bacterial low temperature requirement A protein (LtrA)
MDJIHKML_01477 3.6e-254 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MDJIHKML_01478 6.7e-170 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
MDJIHKML_01479 4.9e-63 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDJIHKML_01480 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDJIHKML_01481 1.2e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDJIHKML_01482 4.7e-63 yodB K Transcriptional regulator, HxlR family
MDJIHKML_01483 1.9e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDJIHKML_01484 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MDJIHKML_01485 4.3e-159 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDJIHKML_01486 1.9e-249 arlS 2.7.13.3 T Histidine kinase
MDJIHKML_01487 2.5e-127 K response regulator
MDJIHKML_01488 2.4e-98 yceD S Uncharacterized ACR, COG1399
MDJIHKML_01489 2.7e-216 ylbM S Belongs to the UPF0348 family
MDJIHKML_01490 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDJIHKML_01491 1.4e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MDJIHKML_01492 5.2e-124 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDJIHKML_01493 1e-212 yqeH S Ribosome biogenesis GTPase YqeH
MDJIHKML_01494 1.6e-93 yqeG S HAD phosphatase, family IIIA
MDJIHKML_01495 1.9e-198 tnpB L Putative transposase DNA-binding domain
MDJIHKML_01496 3.5e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MDJIHKML_01497 1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDJIHKML_01498 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MDJIHKML_01499 2.9e-73 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDJIHKML_01500 3.2e-92
MDJIHKML_01501 5.7e-71 S Protein of unknown function (DUF3021)
MDJIHKML_01502 5.6e-74 K LytTr DNA-binding domain
MDJIHKML_01503 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDJIHKML_01504 6.9e-167 dnaI L Primosomal protein DnaI
MDJIHKML_01505 1.7e-251 dnaB L Replication initiation and membrane attachment
MDJIHKML_01506 2.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDJIHKML_01507 6.9e-107 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDJIHKML_01508 4.8e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDJIHKML_01509 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDJIHKML_01510 5.3e-250 purD 6.3.4.13 F Belongs to the GARS family
MDJIHKML_01511 5e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MDJIHKML_01512 2.7e-111 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MDJIHKML_01513 2e-199 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MDJIHKML_01514 1.5e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDJIHKML_01515 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDJIHKML_01516 6.1e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDJIHKML_01517 7.6e-39 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDJIHKML_01518 2.1e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MDJIHKML_01519 3.6e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDJIHKML_01520 9.6e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDJIHKML_01521 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MDJIHKML_01522 1.1e-124 darA C Flavodoxin
MDJIHKML_01523 9.7e-142 qmcA O prohibitin homologues
MDJIHKML_01524 1.1e-50 L RelB antitoxin
MDJIHKML_01525 2.4e-194 S Bacteriocin helveticin-J
MDJIHKML_01526 7.9e-293 M Peptidase family M1 domain
MDJIHKML_01527 3.2e-178 S SLAP domain
MDJIHKML_01528 1.9e-112 L Putative transposase DNA-binding domain
MDJIHKML_01529 1.2e-97 L Putative transposase DNA-binding domain
MDJIHKML_01530 2.9e-238 mepA V MATE efflux family protein
MDJIHKML_01531 6.6e-167 rocF 3.5.3.1, 3.5.3.11 E Arginase family
MDJIHKML_01532 1.8e-92 S Membrane
MDJIHKML_01533 3.1e-294 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDJIHKML_01534 5.5e-295 G phosphotransferase system
MDJIHKML_01535 1.2e-29 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MDJIHKML_01536 1.7e-148 ybbH K Helix-turn-helix domain, rpiR family
MDJIHKML_01537 0.0
MDJIHKML_01538 4.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MDJIHKML_01539 7.4e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDJIHKML_01540 1.1e-53 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MDJIHKML_01541 1.5e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDJIHKML_01542 7.4e-201 ecsB U ABC transporter
MDJIHKML_01543 2e-135 ecsA V ABC transporter, ATP-binding protein
MDJIHKML_01544 2.8e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
MDJIHKML_01545 1.4e-56
MDJIHKML_01546 1.1e-148 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDJIHKML_01547 8.4e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDJIHKML_01548 0.0 L AAA domain
MDJIHKML_01549 2.4e-231 yhaO L Ser Thr phosphatase family protein
MDJIHKML_01550 6.8e-54 yheA S Belongs to the UPF0342 family
MDJIHKML_01551 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MDJIHKML_01552 2.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDJIHKML_01553 1.6e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MDJIHKML_01554 6.8e-119
MDJIHKML_01555 4.1e-192 5.3.3.2 C FMN-dependent dehydrogenase
MDJIHKML_01556 2.7e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MDJIHKML_01557 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MDJIHKML_01558 6.9e-127 M ErfK YbiS YcfS YnhG
MDJIHKML_01559 8.1e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDJIHKML_01560 1.7e-243 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MDJIHKML_01562 6.4e-54 pspC KT PspC domain
MDJIHKML_01563 5.5e-197 V Beta-lactamase
MDJIHKML_01564 3e-54 yvlA
MDJIHKML_01565 7e-258 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
MDJIHKML_01566 9.1e-40 S Enterocin A Immunity
MDJIHKML_01567 0.0 S domain, Protein
MDJIHKML_01568 3.8e-80 yphH S Cupin domain
MDJIHKML_01569 0.0 sprD D Domain of Unknown Function (DUF1542)
MDJIHKML_01570 2.8e-17 K transcriptional regulator
MDJIHKML_01571 5.5e-71 K transcriptional regulator
MDJIHKML_01572 4.8e-16
MDJIHKML_01573 2.2e-296 ytgP S Polysaccharide biosynthesis protein
MDJIHKML_01574 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDJIHKML_01575 3.9e-119 3.6.1.27 I Acid phosphatase homologues
MDJIHKML_01576 4.4e-91 ndh 1.6.99.3 C NADH dehydrogenase
MDJIHKML_01577 1.5e-112 ndh 1.6.99.3 C NADH dehydrogenase
MDJIHKML_01578 1.5e-30 cydA 1.10.3.14 C ubiquinol oxidase
MDJIHKML_01579 2.9e-260 qacA EGP Major facilitator Superfamily
MDJIHKML_01580 2.4e-220 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDJIHKML_01585 1.8e-253 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDJIHKML_01586 1.4e-101 J Acetyltransferase (GNAT) domain
MDJIHKML_01587 2.7e-111 yjbF S SNARE associated Golgi protein
MDJIHKML_01588 3.2e-152 I alpha/beta hydrolase fold
MDJIHKML_01589 4.5e-160 hipB K Helix-turn-helix
MDJIHKML_01590 2.1e-93 F Nucleoside 2-deoxyribosyltransferase
MDJIHKML_01591 2.1e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MDJIHKML_01592 0.0 fhaB M Rib/alpha-like repeat
MDJIHKML_01593 0.0 fhaB M Rib/alpha-like repeat
MDJIHKML_01594 2.4e-163
MDJIHKML_01595 0.0 ydgH S MMPL family
MDJIHKML_01596 2.3e-96 yobS K Bacterial regulatory proteins, tetR family
MDJIHKML_01597 1.5e-148 3.5.2.6 V Beta-lactamase enzyme family
MDJIHKML_01598 4e-154 corA P CorA-like Mg2+ transporter protein
MDJIHKML_01599 1.3e-235 G Bacterial extracellular solute-binding protein
MDJIHKML_01600 3.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
MDJIHKML_01601 9.4e-147 gtsC P Binding-protein-dependent transport system inner membrane component
MDJIHKML_01602 2.2e-154 gtsB P ABC-type sugar transport systems, permease components
MDJIHKML_01603 7.1e-203 malK P ATPases associated with a variety of cellular activities
MDJIHKML_01604 2.8e-284 pipD E Dipeptidase
MDJIHKML_01605 1.6e-157 endA F DNA RNA non-specific endonuclease
MDJIHKML_01606 1.9e-183 dnaQ 2.7.7.7 L EXOIII
MDJIHKML_01607 1.4e-155 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MDJIHKML_01608 1.5e-115 yviA S Protein of unknown function (DUF421)
MDJIHKML_01609 3.4e-74 S Protein of unknown function (DUF3290)
MDJIHKML_01610 0.0 sdrF M domain protein
MDJIHKML_01611 4.5e-140 pnuC H nicotinamide mononucleotide transporter
MDJIHKML_01612 6.2e-264
MDJIHKML_01613 3.5e-48
MDJIHKML_01614 1.5e-143 S PAS domain
MDJIHKML_01615 4.8e-296 V ABC transporter transmembrane region
MDJIHKML_01616 1.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MDJIHKML_01617 1.8e-127 T Transcriptional regulatory protein, C terminal
MDJIHKML_01618 5.4e-245 T GHKL domain
MDJIHKML_01619 2.1e-86 S Peptidase propeptide and YPEB domain
MDJIHKML_01620 2.3e-97 S Peptidase propeptide and YPEB domain
MDJIHKML_01621 2.8e-76 yybA 2.3.1.57 K Transcriptional regulator
MDJIHKML_01622 6.8e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MDJIHKML_01623 0.0 E ABC transporter, substratebinding protein
MDJIHKML_01624 1.1e-54 ypaA S Protein of unknown function (DUF1304)
MDJIHKML_01625 4.6e-100 S Peptidase propeptide and YPEB domain
MDJIHKML_01626 9.9e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDJIHKML_01627 3.5e-171 coaA 2.7.1.33 F Pantothenic acid kinase
MDJIHKML_01628 6.7e-104 E GDSL-like Lipase/Acylhydrolase
MDJIHKML_01629 9.9e-82 yjcF S Acetyltransferase (GNAT) domain
MDJIHKML_01630 2.8e-151 aatB ET ABC transporter substrate-binding protein
MDJIHKML_01631 9e-110 glnQ 3.6.3.21 E ABC transporter
MDJIHKML_01632 3e-108 glnP P ABC transporter permease
MDJIHKML_01633 1.1e-22 helD 3.6.4.12 L DNA helicase
MDJIHKML_01634 0.0 helD 3.6.4.12 L DNA helicase
MDJIHKML_01635 9.9e-126 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MDJIHKML_01636 8.5e-127 pgm3 5.4.2.11 G Phosphoglycerate mutase family
MDJIHKML_01637 0.0 V FtsX-like permease family
MDJIHKML_01638 1.7e-134 cysA V ABC transporter, ATP-binding protein
MDJIHKML_01639 1.6e-241 S response to antibiotic
MDJIHKML_01640 1.1e-127
MDJIHKML_01641 0.0 3.6.3.8 P P-type ATPase
MDJIHKML_01642 2.1e-64 2.7.1.191 G PTS system fructose IIA component
MDJIHKML_01643 2.1e-48
MDJIHKML_01644 1.9e-15
MDJIHKML_01645 4.2e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
MDJIHKML_01646 1.5e-138 glvR K Helix-turn-helix domain, rpiR family
MDJIHKML_01647 4.1e-269 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
MDJIHKML_01648 4.3e-155
MDJIHKML_01649 3.4e-91
MDJIHKML_01650 4.2e-106 3.2.2.20 K acetyltransferase
MDJIHKML_01653 4.4e-311 asdA 4.1.1.12 E Aminotransferase
MDJIHKML_01654 3.2e-303 aspT P Predicted Permease Membrane Region
MDJIHKML_01655 4.2e-189 S Domain of unknown function (DUF4767)
MDJIHKML_01656 2.5e-184 S Membrane
MDJIHKML_01657 6.4e-150 xth 3.1.11.2 L exodeoxyribonuclease III
MDJIHKML_01658 7.9e-188 K helix_turn_helix, arabinose operon control protein
MDJIHKML_01659 7.8e-188 K helix_turn_helix, arabinose operon control protein
MDJIHKML_01660 4.7e-149 K Helix-turn-helix domain, rpiR family
MDJIHKML_01661 7.7e-202 yleB 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MDJIHKML_01662 3.7e-157 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDJIHKML_01663 0.0 sacX 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDJIHKML_01664 1.6e-298 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MDJIHKML_01665 0.0 2.7.1.208, 2.7.1.211 G phosphotransferase system
MDJIHKML_01666 2.5e-158 K CAT RNA binding domain
MDJIHKML_01667 0.0 M Leucine-rich repeat (LRR) protein
MDJIHKML_01669 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MDJIHKML_01670 1.2e-91
MDJIHKML_01671 1.6e-182
MDJIHKML_01672 9.7e-271 S Uncharacterised protein conserved in bacteria (DUF2326)
MDJIHKML_01673 7.6e-10
MDJIHKML_01679 2.2e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MDJIHKML_01680 4.1e-217 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDJIHKML_01681 2.3e-63 L PFAM Integrase catalytic region
MDJIHKML_01682 1e-136 L transposase activity
MDJIHKML_01683 5.2e-234 L COG3547 Transposase and inactivated derivatives
MDJIHKML_01684 4.6e-266 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
MDJIHKML_01685 4.8e-96 glf 5.4.99.9 M UDP-galactopyranose mutase
MDJIHKML_01686 9.1e-71 glf 5.4.99.9 M Flavin containing amine oxidoreductase
MDJIHKML_01687 4.2e-218 S Psort location CytoplasmicMembrane, score 9.99
MDJIHKML_01688 1.2e-188 M Glycosyltransferase like family 2
MDJIHKML_01689 1.4e-121 M transferase activity, transferring glycosyl groups
MDJIHKML_01690 4.9e-24 M transferase activity, transferring glycosyl groups
MDJIHKML_01691 2.5e-166 glfT1 1.1.1.133 S Glycosyltransferase like family 2
MDJIHKML_01692 1.6e-148 cps1D M Domain of unknown function (DUF4422)
MDJIHKML_01693 1.1e-123 rfbP M Bacterial sugar transferase
MDJIHKML_01694 3.6e-148 ywqE 3.1.3.48 GM PHP domain protein
MDJIHKML_01695 1.5e-125 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MDJIHKML_01696 1.6e-141 epsB M biosynthesis protein
MDJIHKML_01697 4e-174 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDJIHKML_01698 4e-205 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDJIHKML_01699 3.2e-189 S Cysteine-rich secretory protein family
MDJIHKML_01700 0.0 2.7.13.3 M Mycoplasma protein of unknown function, DUF285
MDJIHKML_01701 3.7e-128 M NlpC/P60 family
MDJIHKML_01702 2.3e-126 M NlpC P60 family protein
MDJIHKML_01703 7.6e-84 M NlpC/P60 family
MDJIHKML_01704 1.8e-85 gmk2 2.7.4.8 F Guanylate kinase homologues.
MDJIHKML_01705 5.6e-33
MDJIHKML_01706 1e-279 S O-antigen ligase like membrane protein
MDJIHKML_01707 8.1e-111
MDJIHKML_01708 3.8e-78 nrdI F NrdI Flavodoxin like
MDJIHKML_01709 1.7e-181 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDJIHKML_01710 7.8e-78
MDJIHKML_01711 7.7e-137 yvpB S Peptidase_C39 like family
MDJIHKML_01712 5.2e-53 yitW S Iron-sulfur cluster assembly protein
MDJIHKML_01713 8.8e-47 sufB O assembly protein SufB
MDJIHKML_01714 4.6e-35 sufC O FeS assembly ATPase SufC
MDJIHKML_01715 7.8e-85 S Threonine/Serine exporter, ThrE
MDJIHKML_01716 4.4e-138 thrE S Putative threonine/serine exporter
MDJIHKML_01717 2.1e-293 S ABC transporter
MDJIHKML_01718 3.6e-61
MDJIHKML_01719 1.3e-45 rimL J Acetyltransferase (GNAT) domain
MDJIHKML_01720 1.5e-223 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDJIHKML_01721 0.0 pepF E oligoendopeptidase F
MDJIHKML_01722 6.7e-44 P transmembrane transport
MDJIHKML_01723 7e-265 lctP C L-lactate permease
MDJIHKML_01724 1.4e-62 pdxH S Pyridoxamine 5'-phosphate oxidase
MDJIHKML_01725 7.9e-135 znuB U ABC 3 transport family
MDJIHKML_01726 1e-116 fhuC P ABC transporter
MDJIHKML_01727 6.4e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
MDJIHKML_01728 2.5e-43 K helix_turn_helix, Arsenical Resistance Operon Repressor
MDJIHKML_01729 5.1e-75 K LytTr DNA-binding domain
MDJIHKML_01730 5.5e-47 S Protein of unknown function (DUF3021)
MDJIHKML_01731 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
MDJIHKML_01732 3.3e-169 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MDJIHKML_01733 2.3e-136 fruR K DeoR C terminal sensor domain
MDJIHKML_01734 7.4e-197 fic S Fic/DOC family
MDJIHKML_01735 3.9e-218 natB CP ABC-2 family transporter protein
MDJIHKML_01736 2.6e-166 natA S ABC transporter, ATP-binding protein
MDJIHKML_01737 6.2e-08
MDJIHKML_01738 4e-69
MDJIHKML_01739 2.1e-25
MDJIHKML_01740 8.2e-31 yozG K Transcriptional regulator
MDJIHKML_01741 9e-90
MDJIHKML_01742 8.8e-21
MDJIHKML_01747 8.1e-209 blpT
MDJIHKML_01748 3.4e-106 M Transport protein ComB
MDJIHKML_01749 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MDJIHKML_01750 4.2e-07
MDJIHKML_01752 1.2e-146 K LytTr DNA-binding domain
MDJIHKML_01753 2.8e-233 2.7.13.3 T GHKL domain
MDJIHKML_01757 7e-110
MDJIHKML_01759 5.1e-109 S CAAX protease self-immunity
MDJIHKML_01760 1.2e-216 S CAAX protease self-immunity
MDJIHKML_01761 1.4e-37 S Enterocin A Immunity
MDJIHKML_01762 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MDJIHKML_01763 1.1e-26
MDJIHKML_01764 1.5e-33
MDJIHKML_01765 4e-53 S Enterocin A Immunity
MDJIHKML_01766 9.4e-49 S Enterocin A Immunity
MDJIHKML_01767 7.2e-146 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MDJIHKML_01768 2.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDJIHKML_01769 5.8e-195 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
MDJIHKML_01770 2.5e-121 K response regulator
MDJIHKML_01771 0.0 V ABC transporter
MDJIHKML_01772 1.3e-304 V ABC transporter, ATP-binding protein
MDJIHKML_01773 2e-138 XK27_01040 S Protein of unknown function (DUF1129)
MDJIHKML_01774 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDJIHKML_01775 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
MDJIHKML_01776 3.4e-155 spo0J K Belongs to the ParB family
MDJIHKML_01777 1.3e-137 soj D Sporulation initiation inhibitor
MDJIHKML_01778 7.2e-147 noc K Belongs to the ParB family
MDJIHKML_01779 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MDJIHKML_01780 7.9e-54 cvpA S Colicin V production protein
MDJIHKML_01781 3.5e-182 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDJIHKML_01782 2.5e-149 3.1.3.48 T Tyrosine phosphatase family
MDJIHKML_01783 3.1e-98 azr 1.5.1.36 S NADPH-dependent FMN reductase
MDJIHKML_01784 7.6e-97 nqr 1.5.1.36 S NADPH-dependent FMN reductase
MDJIHKML_01785 1.3e-111 K WHG domain
MDJIHKML_01786 6.9e-19
MDJIHKML_01787 1.1e-277 pipD E Dipeptidase
MDJIHKML_01788 9.8e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MDJIHKML_01789 1.3e-180 hrtB V ABC transporter permease
MDJIHKML_01790 4.8e-96 ygfC K Bacterial regulatory proteins, tetR family
MDJIHKML_01791 2.4e-112 3.1.3.73 G phosphoglycerate mutase
MDJIHKML_01792 2e-140 aroD S Alpha/beta hydrolase family
MDJIHKML_01793 2e-143 S Belongs to the UPF0246 family
MDJIHKML_01794 3.8e-119
MDJIHKML_01795 1.1e-157 2.7.7.12 C Domain of unknown function (DUF4931)
MDJIHKML_01796 9.3e-220 S Putative peptidoglycan binding domain
MDJIHKML_01797 2.6e-26
MDJIHKML_01798 1.3e-252 dtpT U amino acid peptide transporter
MDJIHKML_01799 0.0 pepN 3.4.11.2 E aminopeptidase
MDJIHKML_01800 4.5e-61 lysM M LysM domain
MDJIHKML_01801 4.7e-177
MDJIHKML_01802 2.8e-102 mdtG EGP Major Facilitator Superfamily
MDJIHKML_01803 2.9e-114 mdtG EGP Major facilitator Superfamily
MDJIHKML_01805 6e-213 I transferase activity, transferring acyl groups other than amino-acyl groups
MDJIHKML_01806 1.2e-91 ymdB S Macro domain protein
MDJIHKML_01807 0.0 nisT V ABC transporter
MDJIHKML_01808 3.7e-07
MDJIHKML_01810 1.6e-146 K Helix-turn-helix XRE-family like proteins
MDJIHKML_01811 6.7e-84
MDJIHKML_01812 1.4e-148 malG P ABC transporter permease
MDJIHKML_01813 7.9e-252 malF P Binding-protein-dependent transport system inner membrane component
MDJIHKML_01814 5.9e-214 malE G Bacterial extracellular solute-binding protein
MDJIHKML_01815 1.6e-210 msmX P Belongs to the ABC transporter superfamily
MDJIHKML_01816 7e-264 L COG2963 Transposase and inactivated derivatives
MDJIHKML_01817 9.6e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MDJIHKML_01818 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MDJIHKML_01819 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MDJIHKML_01820 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
MDJIHKML_01821 9.4e-217 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDJIHKML_01822 4.8e-179 yvdE K helix_turn _helix lactose operon repressor
MDJIHKML_01823 6.7e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
MDJIHKML_01824 6.8e-295 V ABC transporter transmembrane region
MDJIHKML_01825 5e-75
MDJIHKML_01826 3.4e-16
MDJIHKML_01827 1.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDJIHKML_01828 2.4e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MDJIHKML_01829 3.3e-57 S Protein conserved in bacteria
MDJIHKML_01830 2.2e-170 L transposase, IS605 OrfB family
MDJIHKML_01831 7.6e-134 cobQ S glutamine amidotransferase
MDJIHKML_01832 9.5e-83 M NlpC/P60 family
MDJIHKML_01833 1.6e-166 EG EamA-like transporter family
MDJIHKML_01834 3.2e-167 EG EamA-like transporter family
MDJIHKML_01835 1.6e-163 yicL EG EamA-like transporter family
MDJIHKML_01836 3.1e-105
MDJIHKML_01837 1.5e-56
MDJIHKML_01838 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDJIHKML_01839 3.2e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDJIHKML_01840 2e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDJIHKML_01843 1.5e-202 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MDJIHKML_01844 3e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
MDJIHKML_01845 1.1e-118 frnE Q DSBA-like thioredoxin domain
MDJIHKML_01846 1.3e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDJIHKML_01847 3.6e-117 M1-798 K Rhodanese Homology Domain
MDJIHKML_01849 1.1e-52 yusE CO Thioredoxin
MDJIHKML_01850 1.7e-241 steT_1 E amino acid
MDJIHKML_01851 8e-142 puuD S peptidase C26
MDJIHKML_01852 3.6e-220 yifK E Amino acid permease
MDJIHKML_01853 3.2e-205 cycA E Amino acid permease
MDJIHKML_01854 7.1e-122
MDJIHKML_01855 0.0 L Transposase
MDJIHKML_01856 6.6e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MDJIHKML_01857 0.0 clpE O AAA domain (Cdc48 subfamily)
MDJIHKML_01858 5.1e-170 S Alpha/beta hydrolase of unknown function (DUF915)
MDJIHKML_01859 1.4e-229 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDJIHKML_01860 5e-125 XK27_06785 V ABC transporter, ATP-binding protein
MDJIHKML_01861 0.0 XK27_06780 V ABC transporter permease
MDJIHKML_01862 9.6e-36
MDJIHKML_01863 7.4e-289 ytgP S Polysaccharide biosynthesis protein
MDJIHKML_01864 4.3e-167 lysA2 M Glycosyl hydrolases family 25
MDJIHKML_01865 4.4e-126 S Protein of unknown function (DUF975)
MDJIHKML_01866 2.7e-61
MDJIHKML_01867 2e-177 pbpX2 V Beta-lactamase
MDJIHKML_01868 3.9e-248 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDJIHKML_01869 7.4e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDJIHKML_01870 2.6e-241 dltB M MBOAT, membrane-bound O-acyltransferase family
MDJIHKML_01871 2e-296 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDJIHKML_01872 7.6e-18 S D-Ala-teichoic acid biosynthesis protein
MDJIHKML_01873 3.6e-40
MDJIHKML_01874 9.1e-217 ywhK S Membrane
MDJIHKML_01875 2.1e-82 ykuL S (CBS) domain
MDJIHKML_01876 0.0 cadA P P-type ATPase
MDJIHKML_01877 5e-194 napA P Sodium/hydrogen exchanger family
MDJIHKML_01878 3.5e-72 S Putative adhesin
MDJIHKML_01879 4.3e-286 V ABC transporter transmembrane region
MDJIHKML_01880 2.8e-154 mutR K Helix-turn-helix XRE-family like proteins
MDJIHKML_01881 3.2e-97 M CHAP domain
MDJIHKML_01882 1.5e-68 K Helix-turn-helix XRE-family like proteins
MDJIHKML_01883 2.7e-120 S CAAX protease self-immunity
MDJIHKML_01884 1.6e-194 S DUF218 domain
MDJIHKML_01885 0.0 macB_3 V ABC transporter, ATP-binding protein
MDJIHKML_01886 1.6e-103 S ECF transporter, substrate-specific component
MDJIHKML_01887 5.6e-186 tcsA S ABC transporter substrate-binding protein PnrA-like
MDJIHKML_01888 5.6e-200 tcsA S ABC transporter substrate-binding protein PnrA-like
MDJIHKML_01889 1.7e-287 xylG 3.6.3.17 S ABC transporter
MDJIHKML_01890 5.1e-207 yufP S Belongs to the binding-protein-dependent transport system permease family
MDJIHKML_01891 2.4e-170 yufQ S Belongs to the binding-protein-dependent transport system permease family
MDJIHKML_01892 1.7e-159 yeaE S Aldo/keto reductase family
MDJIHKML_01893 2.5e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDJIHKML_01894 4.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MDJIHKML_01895 1.4e-127 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MDJIHKML_01896 8.5e-145 cof S haloacid dehalogenase-like hydrolase
MDJIHKML_01897 1.1e-231 pbuG S permease
MDJIHKML_01898 1.2e-263 L COG2963 Transposase and inactivated derivatives
MDJIHKML_01899 5.1e-128 K helix_turn_helix, mercury resistance
MDJIHKML_01900 5e-227 pbuG S permease
MDJIHKML_01901 5.6e-177 pepL 3.4.11.5 E Releases the N-terminal proline from various substrates
MDJIHKML_01902 0.0 oppA2 E Bacterial extracellular solute-binding proteins, family 5 Middle
MDJIHKML_01903 3.4e-223 pbuG S permease
MDJIHKML_01904 1.2e-23
MDJIHKML_01905 3.8e-309 E ABC transporter, substratebinding protein
MDJIHKML_01906 3.9e-75 atkY K Penicillinase repressor
MDJIHKML_01907 1.8e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MDJIHKML_01908 3.7e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MDJIHKML_01909 0.0 copA 3.6.3.54 P P-type ATPase
MDJIHKML_01910 2.7e-175 XK27_05540 S DUF218 domain
MDJIHKML_01911 2.4e-130 WQ51_05710 S Mitochondrial biogenesis AIM24
MDJIHKML_01912 5.5e-118 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MDJIHKML_01913 1.5e-18
MDJIHKML_01914 1.2e-213
MDJIHKML_01915 1.1e-281 clcA P chloride
MDJIHKML_01916 5.8e-274 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDJIHKML_01917 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MDJIHKML_01918 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDJIHKML_01919 3.9e-254 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDJIHKML_01920 5.1e-151 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDJIHKML_01921 3.5e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDJIHKML_01922 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)